Result of FASTA (omim) for
pF1KB4447
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4447, 427 aa
1>>>pF1KB4447 427 - 427 aa - 427 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.2629+/-0.000454; mu= 6.1408+/- 0.028
mean_var=499.6810+/-111.058, 0's: 0 Z-trim(120.8): 1795 B-trim: 0 in 0/57
Lambda= 0.057376
statistics sampled from 33917 (36424) to 33917 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.766), E-opt: 0.2 (0.427), width: 16
Scan time: 9.340
The best scores are: opt bits E(85289)
NP_057360 (OMIM: 607589) serine/threonine-protein ( 427) 2981 261.6 2.7e-69
NP_001186193 (OMIM: 607589) serine/threonine-prote ( 367) 2506 222.2 1.7e-57
NP_733794 (OMIM: 607589) serine/threonine-protein ( 367) 2506 222.2 1.7e-57
NP_005618 (OMIM: 602958) serine/threonine-protein ( 431) 1818 165.4 2.6e-40
NP_001137150 (OMIM: 602958) serine/threonine-prote ( 445) 1818 165.4 2.6e-40
NP_001137149 (OMIM: 602958) serine/threonine-prote ( 459) 1818 165.4 2.7e-40
NP_001137148 (OMIM: 602958) serine/threonine-prote ( 526) 1818 165.5 2.8e-40
XP_011534373 (OMIM: 602958) PREDICTED: serine/thre ( 526) 1818 165.5 2.8e-40
NP_001028750 (OMIM: 607591) serine/threonine-prote ( 496) 1691 155.0 4e-37
NP_037389 (OMIM: 607591) serine/threonine-protein ( 496) 1691 155.0 4e-37
NP_001278924 (OMIM: 602958) serine/threonine-prote ( 387) 1252 118.4 3.1e-26
XP_016855474 (OMIM: 611223,615937) PREDICTED: RAC- ( 418) 1140 109.2 2e-23
NP_001193658 (OMIM: 611223,615937) RAC-gamma serin ( 465) 1140 109.3 2.1e-23
NP_859029 (OMIM: 611223,615937) RAC-gamma serine/t ( 465) 1140 109.3 2.1e-23
XP_005273052 (OMIM: 611223,615937) PREDICTED: RAC- ( 479) 1140 109.3 2.1e-23
NP_005456 (OMIM: 611223,615937) RAC-gamma serine/t ( 479) 1140 109.3 2.1e-23
XP_005273051 (OMIM: 611223,615937) PREDICTED: RAC- ( 479) 1140 109.3 2.1e-23
NP_001229956 (OMIM: 125853,164731,240900) RAC-beta ( 419) 1128 108.2 4e-23
NP_001229957 (OMIM: 125853,164731,240900) RAC-beta ( 419) 1128 108.2 4e-23
XP_011524918 (OMIM: 125853,164731,240900) PREDICTE ( 481) 1128 108.3 4.2e-23
XP_011524921 (OMIM: 125853,164731,240900) PREDICTE ( 481) 1128 108.3 4.2e-23
NP_001617 (OMIM: 125853,164731,240900) RAC-beta se ( 481) 1128 108.3 4.2e-23
XP_011524916 (OMIM: 125853,164731,240900) PREDICTE ( 481) 1128 108.3 4.2e-23
XP_016881959 (OMIM: 125853,164731,240900) PREDICTE ( 481) 1128 108.3 4.2e-23
XP_011524922 (OMIM: 125853,164731,240900) PREDICTE ( 481) 1128 108.3 4.2e-23
XP_011524920 (OMIM: 125853,164731,240900) PREDICTE ( 481) 1128 108.3 4.2e-23
XP_011524917 (OMIM: 125853,164731,240900) PREDICTE ( 481) 1128 108.3 4.2e-23
NP_001014432 (OMIM: 114480,114500,164730,167000,17 ( 480) 1117 107.4 8e-23
NP_005154 (OMIM: 114480,114500,164730,167000,17692 ( 480) 1117 107.4 8e-23
XP_005267458 (OMIM: 114480,114500,164730,167000,17 ( 480) 1117 107.4 8e-23
NP_001014431 (OMIM: 114480,114500,164730,167000,17 ( 480) 1117 107.4 8e-23
XP_011542314 (OMIM: 611223,615937) PREDICTED: RAC- ( 435) 1058 102.5 2.2e-21
NP_003943 (OMIM: 608939) ribosomal protein S6 kina ( 482) 1023 99.7 1.8e-20
XP_016876566 (OMIM: 114480,114500,164730,167000,17 ( 530) 1014 99.0 3.1e-20
XP_016876567 (OMIM: 114480,114500,164730,167000,17 ( 530) 1014 99.0 3.1e-20
XP_016876564 (OMIM: 114480,114500,164730,167000,17 ( 530) 1014 99.0 3.1e-20
XP_016876565 (OMIM: 114480,114500,164730,167000,17 ( 530) 1014 99.0 3.1e-20
NP_001258972 (OMIM: 608938) ribosomal protein S6 k ( 451) 1011 98.6 3.4e-20
NP_001258973 (OMIM: 608938) ribosomal protein S6 k ( 472) 1011 98.6 3.5e-20
NP_001258989 (OMIM: 608938) ribosomal protein S6 k ( 502) 1011 98.7 3.6e-20
NP_003152 (OMIM: 608938) ribosomal protein S6 kina ( 525) 1011 98.7 3.6e-20
NP_733827 (OMIM: 607591) serine/threonine-protein ( 464) 1009 98.5 3.9e-20
XP_011531285 (OMIM: 176975) PREDICTED: protein kin ( 436) 1002 97.8 5.6e-20
XP_006712113 (OMIM: 176975) PREDICTED: protein kin ( 460) 1002 97.9 5.7e-20
XP_011531284 (OMIM: 176975) PREDICTED: protein kin ( 497) 1002 97.9 5.9e-20
XP_016859978 (OMIM: 176975) PREDICTED: protein kin ( 587) 1002 98.1 6.4e-20
XP_011531283 (OMIM: 176975) PREDICTED: protein kin ( 587) 1002 98.1 6.4e-20
XP_016859979 (OMIM: 176975) PREDICTED: protein kin ( 587) 1002 98.1 6.4e-20
XP_016859980 (OMIM: 176975) PREDICTED: protein kin ( 587) 1002 98.1 6.4e-20
XP_011531282 (OMIM: 176975) PREDICTED: protein kin ( 587) 1002 98.1 6.4e-20
>>NP_057360 (OMIM: 607589) serine/threonine-protein kina (427 aa)
initn: 2981 init1: 2981 opt: 2981 Z-score: 1365.1 bits: 261.6 E(85289): 2.7e-69
Smith-Waterman score: 2981; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)
10 20 30 40 50 60
pF1KB4 MQGLLTSGRKPSGGGRCTGRGGWRGQWCLKPWMGGADPPTPTLSCLLLPVPPELPDHCYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MQGLLTSGRKPSGGGRCTGRGGWRGQWCLKPWMGGADPPTPTLSCLLLPVPPELPDHCYR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 MNSSPAGTPSPQPSRANGNINLGPSANPNAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MNSSPAGTPSPQPSRANGNINLGPSANPNAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 YAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 YAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 LFFHLQRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LFFHLQRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 CKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 CKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 QMYENILHQPLQIPGGRTVAACDLLQSLLHKDQRQRLGSKADFLEIKNHVFFSPINWDDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QMYENILHQPLQIPGGRTVAACDLLQSLLHKDQRQRLGSKADFLEIKNHVFFSPINWDDL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 YHKRLTPPFNPNVTGPADLKHFDPEFTQEAVSKSIGCTPDTVASSSGASSAFLGFSYAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 YHKRLTPPFNPNVTGPADLKHFDPEFTQEAVSKSIGCTPDTVASSSGASSAFLGFSYAPE
370 380 390 400 410 420
pF1KB4 DDDILDC
:::::::
NP_057 DDDILDC
>>NP_001186193 (OMIM: 607589) serine/threonine-protein k (367 aa)
initn: 2506 init1: 2506 opt: 2506 Z-score: 1153.1 bits: 222.2 E(85289): 1.7e-57
Smith-Waterman score: 2506; 100.0% identity (100.0% similar) in 367 aa overlap (61-427:1-367)
40 50 60 70 80 90
pF1KB4 PWMGGADPPTPTLSCLLLPVPPELPDHCYRMNSSPAGTPSPQPSRANGNINLGPSANPNA
::::::::::::::::::::::::::::::
NP_001 MNSSPAGTPSPQPSRANGNINLGPSANPNA
10 20 30
100 110 120 130 140 150
pF1KB4 QPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKN
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB4 VRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYL
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB4 HSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEP
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB4 YDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLH
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB4 KDQRQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDQRQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEA
280 290 300 310 320 330
400 410 420
pF1KB4 VSKSIGCTPDTVASSSGASSAFLGFSYAPEDDDILDC
:::::::::::::::::::::::::::::::::::::
NP_001 VSKSIGCTPDTVASSSGASSAFLGFSYAPEDDDILDC
340 350 360
>>NP_733794 (OMIM: 607589) serine/threonine-protein kina (367 aa)
initn: 2506 init1: 2506 opt: 2506 Z-score: 1153.1 bits: 222.2 E(85289): 1.7e-57
Smith-Waterman score: 2506; 100.0% identity (100.0% similar) in 367 aa overlap (61-427:1-367)
40 50 60 70 80 90
pF1KB4 PWMGGADPPTPTLSCLLLPVPPELPDHCYRMNSSPAGTPSPQPSRANGNINLGPSANPNA
::::::::::::::::::::::::::::::
NP_733 MNSSPAGTPSPQPSRANGNINLGPSANPNA
10 20 30
100 110 120 130 140 150
pF1KB4 QPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 QPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKN
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB4 VRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 VRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYL
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB4 HSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 HSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEP
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB4 YDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 YDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLH
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB4 KDQRQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 KDQRQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEA
280 290 300 310 320 330
400 410 420
pF1KB4 VSKSIGCTPDTVASSSGASSAFLGFSYAPEDDDILDC
:::::::::::::::::::::::::::::::::::::
NP_733 VSKSIGCTPDTVASSSGASSAFLGFSYAPEDDDILDC
340 350 360
>>NP_005618 (OMIM: 602958) serine/threonine-protein kina (431 aa)
initn: 1816 init1: 1712 opt: 1818 Z-score: 844.8 bits: 165.4 E(85289): 2.6e-40
Smith-Waterman score: 1818; 68.6% identity (88.4% similar) in 388 aa overlap (41-425:52-431)
20 30 40 50 60 70
pF1KB4 PSGGGRCTGRGGWRGQWCLKPWMGGADPPTPTLSCLLLPVPPELPDHCYRMNSSPAGTPS
: .. .: :. :. ::..: .:
NP_005 AILIAFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPEL---MNANP--SPP
30 40 50 60 70
80 90 100 110 120 130
pF1KB4 PQPSRANGNINLGPSANPNAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKS
:.::. .::::::.::.:.:.:: ::::::::..::::::..:.. .::::::::::.
NP_005 PSPSQ---QINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKA
80 90 100 110 120 130
140 150 160 170 180 190
pF1KB4 ILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERR
::::::..:::.::.::::::.:::::::..:::: .::::::::.::::::.::::::
NP_005 ILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERC
140 150 160 170 180 190
200 210 220 230 240 250
pF1KB4 FLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDT
::::::::::::.:::.::::::::.:::::::::::: :::.::::::::::..: ..:
NP_005 FLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNST
200 210 220 230 240 250
260 270 280 290 300 310
pF1KB4 TSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQP
::::::::::::::::.:.::::.::::::::::::::.:::::::.....::.:::..:
NP_005 TSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKP
260 270 280 290 300 310
320 330 340 350 360 370
pF1KB4 LQIPGGRTVAACDLLQSLLHKDQRQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFN
::. . : .: ::..::.::. .:::.: ::.:::.::::: :::::: .:..:::::
NP_005 LQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFN
320 330 340 350 360 370
380 390 400 410 420
pF1KB4 PNVTGPADLKHFDPEFTQEAVSKSIGCTPDTV---ASSSGASSAFLGFSYAPEDDDILDC
:::.:: ::.:::::::.: : .::: .::.: :: . :. ::::::::: :..:
NP_005 PNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTDSFL
380 390 400 410 420 430
>>NP_001137150 (OMIM: 602958) serine/threonine-protein k (445 aa)
initn: 1816 init1: 1712 opt: 1818 Z-score: 844.6 bits: 165.4 E(85289): 2.6e-40
Smith-Waterman score: 1818; 68.6% identity (88.4% similar) in 388 aa overlap (41-425:66-445)
20 30 40 50 60 70
pF1KB4 PSGGGRCTGRGGWRGQWCLKPWMGGADPPTPTLSCLLLPVPPELPDHCYRMNSSPAGTPS
: .. .: :. :. ::..: .:
NP_001 LSGLAFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPEL---MNANP--SPP
40 50 60 70 80 90
80 90 100 110 120 130
pF1KB4 PQPSRANGNINLGPSANPNAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKS
:.::. .::::::.::.:.:.:: ::::::::..::::::..:.. .::::::::::.
NP_001 PSPSQ---QINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKA
100 110 120 130 140
140 150 160 170 180 190
pF1KB4 ILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERR
::::::..:::.::.::::::.:::::::..:::: .::::::::.::::::.::::::
NP_001 ILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERC
150 160 170 180 190 200
200 210 220 230 240 250
pF1KB4 FLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDT
::::::::::::.:::.::::::::.:::::::::::: :::.::::::::::..: ..:
NP_001 FLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNST
210 220 230 240 250 260
260 270 280 290 300 310
pF1KB4 TSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQP
::::::::::::::::.:.::::.::::::::::::::.:::::::.....::.:::..:
NP_001 TSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKP
270 280 290 300 310 320
320 330 340 350 360 370
pF1KB4 LQIPGGRTVAACDLLQSLLHKDQRQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFN
::. . : .: ::..::.::. .:::.: ::.:::.::::: :::::: .:..:::::
NP_001 LQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFN
330 340 350 360 370 380
380 390 400 410 420
pF1KB4 PNVTGPADLKHFDPEFTQEAVSKSIGCTPDTV---ASSSGASSAFLGFSYAPEDDDILDC
:::.:: ::.:::::::.: : .::: .::.: :: . :. ::::::::: :..:
NP_001 PNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTDSFL
390 400 410 420 430 440
>>NP_001137149 (OMIM: 602958) serine/threonine-protein k (459 aa)
initn: 1816 init1: 1712 opt: 1818 Z-score: 844.5 bits: 165.4 E(85289): 2.7e-40
Smith-Waterman score: 1818; 68.6% identity (88.4% similar) in 388 aa overlap (41-425:80-459)
20 30 40 50 60 70
pF1KB4 PSGGGRCTGRGGWRGQWCLKPWMGGADPPTPTLSCLLLPVPPELPDHCYRMNSSPAGTPS
: .. .: :. :. ::..: .:
NP_001 PPLKAFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPEL---MNANP--SPP
50 60 70 80 90 100
80 90 100 110 120 130
pF1KB4 PQPSRANGNINLGPSANPNAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKS
:.::. .::::::.::.:.:.:: ::::::::..::::::..:.. .::::::::::.
NP_001 PSPSQ---QINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKA
110 120 130 140 150 160
140 150 160 170 180 190
pF1KB4 ILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERR
::::::..:::.::.::::::.:::::::..:::: .::::::::.::::::.::::::
NP_001 ILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERC
170 180 190 200 210 220
200 210 220 230 240 250
pF1KB4 FLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDT
::::::::::::.:::.::::::::.:::::::::::: :::.::::::::::..: ..:
NP_001 FLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNST
230 240 250 260 270 280
260 270 280 290 300 310
pF1KB4 TSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQP
::::::::::::::::.:.::::.::::::::::::::.:::::::.....::.:::..:
NP_001 TSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKP
290 300 310 320 330 340
320 330 340 350 360 370
pF1KB4 LQIPGGRTVAACDLLQSLLHKDQRQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFN
::. . : .: ::..::.::. .:::.: ::.:::.::::: :::::: .:..:::::
NP_001 LQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFN
350 360 370 380 390 400
380 390 400 410 420
pF1KB4 PNVTGPADLKHFDPEFTQEAVSKSIGCTPDTV---ASSSGASSAFLGFSYAPEDDDILDC
:::.:: ::.:::::::.: : .::: .::.: :: . :. ::::::::: :..:
NP_001 PNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTDSFL
410 420 430 440 450
>>NP_001137148 (OMIM: 602958) serine/threonine-protein k (526 aa)
initn: 1840 init1: 1712 opt: 1818 Z-score: 844.0 bits: 165.5 E(85289): 2.8e-40
Smith-Waterman score: 1818; 68.6% identity (88.4% similar) in 388 aa overlap (41-425:147-526)
20 30 40 50 60 70
pF1KB4 PSGGGRCTGRGGWRGQWCLKPWMGGADPPTPTLSCLLLPVPPELPDHCYRMNSSPAGTPS
: .. .: :. :. ::..: .:
NP_001 NDDPAFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPEL---MNANP--SPP
120 130 140 150 160 170
80 90 100 110 120 130
pF1KB4 PQPSRANGNINLGPSANPNAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKS
:.::. .::::::.::.:.:.:: ::::::::..::::::..:.. .::::::::::.
NP_001 PSPSQ---QINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKA
180 190 200 210 220
140 150 160 170 180 190
pF1KB4 ILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERR
::::::..:::.::.::::::.:::::::..:::: .::::::::.::::::.::::::
NP_001 ILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERC
230 240 250 260 270 280
200 210 220 230 240 250
pF1KB4 FLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDT
::::::::::::.:::.::::::::.:::::::::::: :::.::::::::::..: ..:
NP_001 FLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNST
290 300 310 320 330 340
260 270 280 290 300 310
pF1KB4 TSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQP
::::::::::::::::.:.::::.::::::::::::::.:::::::.....::.:::..:
NP_001 TSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKP
350 360 370 380 390 400
320 330 340 350 360 370
pF1KB4 LQIPGGRTVAACDLLQSLLHKDQRQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFN
::. . : .: ::..::.::. .:::.: ::.:::.::::: :::::: .:..:::::
NP_001 LQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFN
410 420 430 440 450 460
380 390 400 410 420
pF1KB4 PNVTGPADLKHFDPEFTQEAVSKSIGCTPDTV---ASSSGASSAFLGFSYAPEDDDILDC
:::.:: ::.:::::::.: : .::: .::.: :: . :. ::::::::: :..:
NP_001 PNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTDSFL
470 480 490 500 510 520
>>XP_011534373 (OMIM: 602958) PREDICTED: serine/threonin (526 aa)
initn: 1840 init1: 1712 opt: 1818 Z-score: 844.0 bits: 165.5 E(85289): 2.8e-40
Smith-Waterman score: 1818; 68.6% identity (88.4% similar) in 388 aa overlap (41-425:147-526)
20 30 40 50 60 70
pF1KB4 PSGGGRCTGRGGWRGQWCLKPWMGGADPPTPTLSCLLLPVPPELPDHCYRMNSSPAGTPS
: .. .: :. :. ::..: .:
XP_011 NDDPAFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPEL---MNANP--SPP
120 130 140 150 160 170
80 90 100 110 120 130
pF1KB4 PQPSRANGNINLGPSANPNAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKS
:.::. .::::::.::.:.:.:: ::::::::..::::::..:.. .::::::::::.
XP_011 PSPSQ---QINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKA
180 190 200 210 220
140 150 160 170 180 190
pF1KB4 ILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERR
::::::..:::.::.::::::.:::::::..:::: .::::::::.::::::.::::::
XP_011 ILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERC
230 240 250 260 270 280
200 210 220 230 240 250
pF1KB4 FLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDT
::::::::::::.:::.::::::::.:::::::::::: :::.::::::::::..: ..:
XP_011 FLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNST
290 300 310 320 330 340
260 270 280 290 300 310
pF1KB4 TSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQP
::::::::::::::::.:.::::.::::::::::::::.:::::::.....::.:::..:
XP_011 TSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKP
350 360 370 380 390 400
320 330 340 350 360 370
pF1KB4 LQIPGGRTVAACDLLQSLLHKDQRQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFN
::. . : .: ::..::.::. .:::.: ::.:::.::::: :::::: .:..:::::
XP_011 LQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFN
410 420 430 440 450 460
380 390 400 410 420
pF1KB4 PNVTGPADLKHFDPEFTQEAVSKSIGCTPDTV---ASSSGASSAFLGFSYAPEDDDILDC
:::.:: ::.:::::::.: : .::: .::.: :: . :. ::::::::: :..:
XP_011 PNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTDSFL
470 480 490 500 510 520
>>NP_001028750 (OMIM: 607591) serine/threonine-protein k (496 aa)
initn: 1695 init1: 1632 opt: 1691 Z-score: 787.4 bits: 155.0 E(85289): 4e-37
Smith-Waterman score: 1691; 69.4% identity (88.9% similar) in 350 aa overlap (79-425:146-495)
50 60 70 80 90 100
pF1KB4 PVPPELPDHCYRMNSSPAGTPSPQPSRANGNINLGPSANPNAQPTDFDFLKVIGKGNYGK
:::::::.::.:.:::::::::::::..::
NP_001 FLQMDSPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGK
120 130 140 150 160 170
110 120 130 140 150 160
pF1KB4 VLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEK
::::::: :: :::::::::: .:..:::.::::::.::::::.:::::::.::::: ::
NP_001 VLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEK
180 190 200 210 220 230
170 180 190 200 210 220
pF1KB4 LYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLD
::::::.:::::::::::::: : : ::::::::.:::.:::::..:.::::::::::::
NP_001 LYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLD
240 250 260 270 280 290
230 240 250 260 270 280
pF1KB4 CQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEML
::::::::::::::. :::.:::::::::::::.::.::: .::::::::::::::
NP_001 SVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEML
300 310 320 330 340 350
290 300 310 320 330 340
pF1KB4 HGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQRQRLGSKADFLEIKN
.:::::: .::..::.::::.::.. : ...: ..:. ::.::...:::.: :::::.:
NP_001 YGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQN
360 370 380 390 400 410
350 360 370 380 390 400
pF1KB4 HVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEAVSKSIGCTPD-TVASSS-
: :: ..: :: .:.. :::::::.:: :...:: ::.:.: :. . : .....:
NP_001 HPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASV
420 430 440 450 460 470
410 420
pF1KB4 -GASSAFLGFSYAPEDDDILDC
:..::.:::::: ..:..
NP_001 LEADDAFVGFSYAPPSEDLFL
480 490
>>NP_037389 (OMIM: 607591) serine/threonine-protein kina (496 aa)
initn: 1695 init1: 1632 opt: 1691 Z-score: 787.4 bits: 155.0 E(85289): 4e-37
Smith-Waterman score: 1691; 69.4% identity (88.9% similar) in 350 aa overlap (79-425:146-495)
50 60 70 80 90 100
pF1KB4 PVPPELPDHCYRMNSSPAGTPSPQPSRANGNINLGPSANPNAQPTDFDFLKVIGKGNYGK
:::::::.::.:.:::::::::::::..::
NP_037 FLQMDSPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGK
120 130 140 150 160 170
110 120 130 140 150 160
pF1KB4 VLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEK
::::::: :: :::::::::: .:..:::.::::::.::::::.:::::::.::::: ::
NP_037 VLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEK
180 190 200 210 220 230
170 180 190 200 210 220
pF1KB4 LYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLD
::::::.:::::::::::::: : : ::::::::.:::.:::::..:.::::::::::::
NP_037 LYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLD
240 250 260 270 280 290
230 240 250 260 270 280
pF1KB4 CQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEML
::::::::::::::. :::.:::::::::::::.::.::: .::::::::::::::
NP_037 SVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEML
300 310 320 330 340 350
290 300 310 320 330 340
pF1KB4 HGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQRQRLGSKADFLEIKN
.:::::: .::..::.::::.::.. : ...: ..:. ::.::...:::.: :::::.:
NP_037 YGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQN
360 370 380 390 400 410
350 360 370 380 390 400
pF1KB4 HVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEAVSKSIGCTPD-TVASSS-
: :: ..: :: .:.. :::::::.:: :...:: ::.:.: :. . : .....:
NP_037 HPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASV
420 430 440 450 460 470
410 420
pF1KB4 -GASSAFLGFSYAPEDDDILDC
:..::.:::::: ..:..
NP_037 LEADDAFVGFSYAPPSEDLFL
480 490
427 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 15:03:05 2016 done: Thu Nov 3 15:03:06 2016
Total Scan time: 9.340 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]