Result of FASTA (omim) for
pF1KB4347
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4347, 212 aa
1>>>pF1KB4347 212 - 212 aa - 212 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2492+/-0.000443; mu= 14.2310+/- 0.028
mean_var=91.0074+/-18.096, 0's: 0 Z-trim(111.9): 436 B-trim: 899 in 1/53
Lambda= 0.134442
statistics sampled from 20093 (20604) to 20093 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.613), E-opt: 0.2 (0.242), width: 16
Scan time: 5.790
The best scores are: opt bits E(85289)
NP_002856 (OMIM: 179509) ras-related protein Rab-2 ( 212) 1392 280.1 1.8e-75
NP_116235 (OMIM: 607466) ras-related protein Rab-2 ( 216) 1191 241.1 1e-63
NP_001229573 (OMIM: 179509) ras-related protein Ra ( 188) 1132 229.6 2.5e-60
NP_001156852 (OMIM: 607466) ras-related protein Ra ( 170) 889 182.5 3.6e-46
NP_057406 (OMIM: 612673) ras-related protein Rab-1 ( 215) 825 170.1 2.3e-42
XP_016877199 (OMIM: 607466) PREDICTED: ras-related ( 171) 788 162.9 2.9e-40
NP_004569 (OMIM: 179511) ras-related protein Rab-4 ( 218) 713 148.4 8.2e-36
XP_016877200 (OMIM: 607466) PREDICTED: ras-related ( 151) 707 147.1 1.4e-35
NP_057238 (OMIM: 612945) ras-related protein Rab-4 ( 213) 694 144.7 1e-34
XP_016877201 (OMIM: 607466) PREDICTED: ras-related ( 147) 692 144.2 1e-34
NP_057614 (OMIM: 613532) ras-related protein Rab-8 ( 207) 635 133.3 2.8e-31
NP_004209 (OMIM: 604198) ras-related protein Rab-1 ( 218) 615 129.4 4.3e-30
NP_005361 (OMIM: 165040) ras-related protein Rab-8 ( 207) 609 128.2 9.3e-30
NP_004654 (OMIM: 605570) ras-related protein Rab-1 ( 216) 604 127.3 1.9e-29
NP_741995 (OMIM: 300774) ras-related protein Rab-3 ( 213) 599 126.3 3.7e-29
XP_011526322 (OMIM: 165040) PREDICTED: ras-related ( 215) 598 126.1 4.2e-29
NP_004152 (OMIM: 179508) ras-related protein Rab-1 ( 205) 597 125.9 4.7e-29
NP_002861 (OMIM: 602672) ras-related protein Rab-1 ( 203) 592 124.9 9.1e-29
NP_057215 (OMIM: 612672) ras-related protein Rab-1 ( 200) 588 124.1 1.5e-28
NP_112243 (OMIM: 612565) ras-related protein Rab-1 ( 201) 585 123.6 2.3e-28
NP_067075 (OMIM: 602207,614222) ras-related protei ( 206) 576 121.8 7.9e-28
NP_001006639 (OMIM: 609956) ras-related protein Ra ( 223) 569 120.5 2.1e-27
NP_001317400 (OMIM: 609956) ras-related protein Ra ( 196) 568 120.3 2.2e-27
NP_001157461 (OMIM: 609956) ras-related protein Ra ( 228) 568 120.3 2.5e-27
NP_783865 (OMIM: 609956) ras-related protein Rab-3 ( 216) 566 119.9 3.1e-27
NP_065120 (OMIM: 612942) ras-related protein Rab-2 ( 213) 561 118.9 6.1e-27
NP_001272989 (OMIM: 605693) ras-related protein Ra ( 203) 541 115.0 8.6e-26
NP_055303 (OMIM: 605693) ras-related protein Rab-3 ( 203) 541 115.0 8.6e-26
NP_001272988 (OMIM: 605693) ras-related protein Ra ( 203) 541 115.0 8.6e-26
NP_001272990 (OMIM: 605693) ras-related protein Ra ( 203) 541 115.0 8.6e-26
NP_055168 (OMIM: 605455) ras-related protein Rab-2 ( 256) 541 115.1 1e-25
NP_001294982 (OMIM: 605455) ras-related protein Ra ( 190) 525 111.9 7.1e-25
NP_001193765 (OMIM: 605570) ras-related protein Ra ( 155) 519 110.7 1.4e-24
XP_011526466 (OMIM: 179490) PREDICTED: ras-related ( 220) 515 110.0 3e-24
NP_002857 (OMIM: 179490) ras-related protein Rab-3 ( 220) 515 110.0 3e-24
NP_006852 (OMIM: 604199) ras-related protein Rab-3 ( 201) 501 107.3 1.9e-23
XP_011523392 (OMIM: 604037) PREDICTED: ras-related ( 216) 498 106.7 2.9e-23
XP_011523393 (OMIM: 604037) PREDICTED: ras-related ( 216) 498 106.7 2.9e-23
NP_958842 (OMIM: 604037) ras-related protein Rab-5 ( 216) 498 106.7 2.9e-23
NP_004574 (OMIM: 604037) ras-related protein Rab-5 ( 216) 498 106.7 2.9e-23
NP_001238968 (OMIM: 604037) ras-related protein Ra ( 249) 498 106.8 3.2e-23
NP_001020471 (OMIM: 616448) ras-related protein Ra ( 244) 494 106.0 5.4e-23
XP_005269108 (OMIM: 179514) PREDICTED: ras-related ( 215) 488 104.8 1.1e-22
XP_005269109 (OMIM: 179514) PREDICTED: ras-related ( 215) 488 104.8 1.1e-22
NP_001238965 (OMIM: 179514) ras-related protein Ra ( 215) 488 104.8 1.1e-22
NP_002859 (OMIM: 179514) ras-related protein Rab-5 ( 215) 488 104.8 1.1e-22
NP_057661 (OMIM: 615852) ras-related protein Rab-6 ( 208) 483 103.8 2.1e-22
NP_004274 (OMIM: 604350) ras-related protein Rab-3 ( 219) 478 102.9 4.3e-22
XP_016857447 (OMIM: 179510) PREDICTED: ras-related ( 219) 476 102.5 5.7e-22
NP_002858 (OMIM: 179510) ras-related protein Rab-3 ( 219) 476 102.5 5.7e-22
>>NP_002856 (OMIM: 179509) ras-related protein Rab-2A is (212 aa)
initn: 1392 init1: 1392 opt: 1392 Z-score: 1475.8 bits: 280.1 E(85289): 1.8e-75
Smith-Waterman score: 1392; 100.0% identity (100.0% similar) in 212 aa overlap (1-212:1-212)
10 20 30 40 50 60
pF1KB4 MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 DTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 SDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINN
130 140 150 160 170 180
190 200 210
pF1KB4 EANGIKIGPQHAATNATHAGNQGGQQAGGGCC
::::::::::::::::::::::::::::::::
NP_002 EANGIKIGPQHAATNATHAGNQGGQQAGGGCC
190 200 210
>>NP_116235 (OMIM: 607466) ras-related protein Rab-2B is (216 aa)
initn: 1188 init1: 1165 opt: 1191 Z-score: 1265.0 bits: 241.1 E(85289): 1e-63
Smith-Waterman score: 1191; 83.8% identity (96.3% similar) in 216 aa overlap (1-212:1-216)
10 20 30 40 50 60
pF1KB4 MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIW
:.:::::::::::::::::::::::::::::::::::::::::::::..:::::::::::
NP_116 MTYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 DTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNK
:::::::::::::::::::::::::::::::.::::::.:::::::::.:::::::::::
NP_116 DTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 SDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINN
:::::::.::.:::::::::::::::::::::: ::::::::::::::.:::.:.::..:
NP_116 SDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDVHN
130 140 150 160 170 180
190 200 210
pF1KB4 EANGIKIGPQHAATNAT--HAGNQGGQQAGG--GCC
::::::::::.. .... :....... :. :::
NP_116 EANGIKIGPQQSISTSVGPSASQRNSRDIGSNSGCC
190 200 210
>>NP_001229573 (OMIM: 179509) ras-related protein Rab-2A (188 aa)
initn: 1132 init1: 1132 opt: 1132 Z-score: 1204.0 bits: 229.6 E(85289): 2.5e-60
Smith-Waterman score: 1170; 88.7% identity (88.7% similar) in 212 aa overlap (1-212:1-188)
10 20 30 40 50 60
pF1KB4 MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIW
::::::::::::::::: :::::::::::::::::::
NP_001 MAYAYLFKYIIIGDTGV------------------------EFGARMITIDGKQIKLQIW
10 20 30
70 80 90 100 110 120
pF1KB4 DTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNK
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB4 SDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINN
100 110 120 130 140 150
190 200 210
pF1KB4 EANGIKIGPQHAATNATHAGNQGGQQAGGGCC
::::::::::::::::::::::::::::::::
NP_001 EANGIKIGPQHAATNATHAGNQGGQQAGGGCC
160 170 180
>>NP_001156852 (OMIM: 607466) ras-related protein Rab-2B (170 aa)
initn: 882 init1: 859 opt: 889 Z-score: 949.8 bits: 182.5 E(85289): 3.6e-46
Smith-Waterman score: 889; 80.0% identity (95.3% similar) in 170 aa overlap (47-212:1-170)
20 30 40 50 60 70
pF1KB4 VGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYY
:..:::::::::::::::::::::::::::
NP_001 MVNIDGKQIKLQIWDTAGQESFRSITRSYY
10 20 30
80 90 100 110 120 130
pF1KB4 RGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEA
:::::::::::::::.::::::.:::::::::.::::::::::::::::::.::.:::::
NP_001 RGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEA
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB4 FAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNA
::::::::::::::::: ::::::::::::::.:::.:.::..:::::::::::.. ...
NP_001 FAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSISTS
100 110 120 130 140 150
200 210
pF1KB4 T--HAGNQGGQQAGG--GCC
. :....... :. :::
NP_001 VGPSASQRNSRDIGSNSGCC
160 170
>>NP_057406 (OMIM: 612673) ras-related protein Rab-14 [H (215 aa)
initn: 806 init1: 787 opt: 825 Z-score: 881.4 bits: 170.1 E(85289): 2.3e-42
Smith-Waterman score: 825; 58.9% identity (84.2% similar) in 209 aa overlap (3-211:8-215)
10 20 30 40 50
pF1KB4 MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQI
:.:.:::::::: :::::::: :::.:.:. :::::::.:.: ..:..:
NP_057 MATAPYNYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIM
::::::::::: ::..::::::::::::.:::::::.:.:::..:: :::. .: : ::.
NP_057 KLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVII
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB4 LIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGV
:::::.:::..:.: ::.. ::.:.::.:.:.::::. :::.::...::.::..::.:
NP_057 LIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGS
130 140 150 160 170 180
180 190 200 210
pF1KB4 FDINNEANGIKIGPQHAATNATHAGNQGGQQAGGGCC
.:.: .:.. :. : .. ... :. : ::
NP_057 LDLNAAESGVQHKPS-APQGGRLTSEPQPQREGCGC
190 200 210
>>XP_016877199 (OMIM: 607466) PREDICTED: ras-related pro (171 aa)
initn: 790 init1: 769 opt: 788 Z-score: 843.9 bits: 162.9 E(85289): 2.9e-40
Smith-Waterman score: 788; 79.2% identity (94.8% similar) in 154 aa overlap (63-212:18-171)
40 50 60 70 80 90
pF1KB4 PVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRD
:::::::::::::::::::::::::::::.
XP_016 MYANVFIVFIVLTGVPQAGQESFRSITRSYYRGAAGALLVYDITRRE
10 20 30 40
100 110 120 130 140 150
pF1KB4 TFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKT
::::::.:::::::::.::::::::::::::::::.::.:::::::::::::::::::::
XP_016 TFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKT
50 60 70 80 90 100
160 170 180 190 200
pF1KB4 ASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNAT--HAGNQGGQQAGG-
: ::::::::::::::.:::.:.::..:::::::::::.. .... :....... :.
XP_016 ACNVEEAFINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSISTSVGPSASQRNSRDIGSN
110 120 130 140 150 160
210
pF1KB4 -GCC
:::
XP_016 SGCC
170
>>NP_004569 (OMIM: 179511) ras-related protein Rab-4A is (218 aa)
initn: 713 init1: 713 opt: 713 Z-score: 763.9 bits: 148.4 E(85289): 8.2e-36
Smith-Waterman score: 713; 57.5% identity (82.8% similar) in 186 aa overlap (3-188:10-195)
10 20 30 40 50
pF1KB4 MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGK
: .:::...::..:.:::::: :: .:.:. . :::::::...:.. ::
NP_004 MSQTAMSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 QIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMV
.::::::::::: :::.:::::::::::::::::: :.:.: ::.:: :::. ...:.:
NP_004 YVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB4 IMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQE
:.: :::.::.. ::: :. ::.:. :.:.:::: :. ::::::.. :..: .::.
NP_004 IILCGNKKDLDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIES
130 140 150 160 170 180
180 190 200 210
pF1KB4 GVFDINNEANGIKIGPQHAATNATHAGNQGGQQAGGGCC
: .: . ..::. :
NP_004 GELDPERMGSGIQYGDAALRQLRSPRRAQAPNAQECGC
190 200 210
>>XP_016877200 (OMIM: 607466) PREDICTED: ras-related pro (151 aa)
initn: 703 init1: 680 opt: 707 Z-score: 759.7 bits: 147.1 E(85289): 1.4e-35
Smith-Waterman score: 707; 74.3% identity (91.9% similar) in 148 aa overlap (69-212:4-151)
40 50 60 70 80 90
pF1KB4 IGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLT
.: .: :::::::::::::::.::::::
XP_016 MENKSNCKSGIRGAAGALLVYDITRRETFNHLT
10 20 30
100 110 120 130 140 150
pF1KB4 TWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEE
.:::::::::.::::::::::::::::::.::.:::::::::::::::::::::: ::::
XP_016 SWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEE
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB4 AFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNAT--HAGNQGGQQAGG--GCC
::::::::::.:::.:.::..:::::::::::.. .... :....... :. :::
XP_016 AFINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSISTSVGPSASQRNSRDIGSNSGCC
100 110 120 130 140 150
>>NP_057238 (OMIM: 612945) ras-related protein Rab-4B [H (213 aa)
initn: 694 init1: 694 opt: 694 Z-score: 744.1 bits: 144.7 E(85289): 1e-34
Smith-Waterman score: 694; 55.9% identity (81.2% similar) in 186 aa overlap (3-188:5-190)
10 20 30 40 50
pF1KB4 MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQ
: .:::...::..:.:::::: :: ...:. . :::::::.:.... :: .:::
NP_057 MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 IWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIG
:::::::: :::.:::::::::::::::::: :.:.: :..:: ::: .. :.:..: :
NP_057 IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB4 NKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDI
::.::. .::: :. ::.:. :.:.:::: :. ::::::.. :. : .::. : .:
NP_057 NKKDLDPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIDSGELDP
130 140 150 160 170 180
180 190 200 210
pF1KB4 NNEANGIKIGPQHAATNATHAGNQGGQQAGGGCC
. ..::. :
NP_057 ERMGSGIQYGDASLRQLRQPRSAQAVAPQPCGC
190 200 210
>>XP_016877201 (OMIM: 607466) PREDICTED: ras-related pro (147 aa)
initn: 736 init1: 673 opt: 692 Z-score: 744.1 bits: 144.2 E(85289): 1e-34
Smith-Waterman score: 692; 77.0% identity (94.2% similar) in 139 aa overlap (78-212:9-147)
50 60 70 80 90 100
pF1KB4 ITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQH
::::::::::::::.::::::.::::::::
XP_016 MGTERLIWGAAGALLVYDITRRETFNHLTSWLEDARQH
10 20 30
110 120 130 140 150 160
pF1KB4 SNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEI
:.::::::::::::::::::.::.:::::::::::::::::::::: :::::::::::::
XP_016 SSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAFINTAKEI
40 50 60 70 80 90
170 180 190 200 210
pF1KB4 YEKIQEGVFDINNEANGIKIGPQHAATNAT--HAGNQGGQQAGG--GCC
:.:::.:.::..:::::::::::.. .... :....... :. :::
XP_016 YRKIQQGLFDVHNEANGIKIGPQQSISTSVGPSASQRNSRDIGSNSGCC
100 110 120 130 140
212 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:39:49 2016 done: Fri Nov 4 20:39:50 2016
Total Scan time: 5.790 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]