Result of FASTA (omim) for
pF1KB4327
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4327, 538 aa
1>>>pF1KB4327 538 - 538 aa - 538 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2586+/-0.000309; mu= 19.4925+/- 0.019
mean_var=83.2734+/-17.016, 0's: 0 Z-trim(117.4): 182 B-trim: 0 in 0/51
Lambda= 0.140547
statistics sampled from 29219 (29421) to 29219 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.704), E-opt: 0.2 (0.345), width: 16
Scan time: 11.290
The best scores are: opt bits E(85289)
XP_005267804 (OMIM: 611461) PREDICTED: solute carr ( 538) 3645 748.9 8.7e-216
NP_065105 (OMIM: 611461) solute carrier family 22 ( 538) 3645 748.9 8.7e-216
XP_016876850 (OMIM: 611461) PREDICTED: solute carr ( 538) 3645 748.9 8.7e-216
NP_057693 (OMIM: 611461) solute carrier family 22 ( 520) 2634 543.9 4.4e-154
XP_016876851 (OMIM: 611461) PREDICTED: solute carr ( 520) 2634 543.9 4.4e-154
XP_005267805 (OMIM: 611461) PREDICTED: solute carr ( 412) 1931 401.3 3e-111
NP_001275979 (OMIM: 611461) solute carrier family ( 302) 1134 239.6 1.1e-62
NP_056297 (OMIM: 611697) solute carrier family 22 ( 686) 936 199.7 2.4e-50
XP_016866669 (OMIM: 611697) PREDICTED: solute carr ( 512) 895 191.3 6e-48
XP_011513103 (OMIM: 611697) PREDICTED: solute carr ( 710) 889 190.2 1.8e-47
XP_016866670 (OMIM: 611697) PREDICTED: solute carr ( 405) 751 162.0 3.1e-39
NP_001273384 (OMIM: 611697) solute carrier family ( 405) 751 162.0 3.1e-39
XP_016866675 (OMIM: 611697) PREDICTED: solute carr ( 405) 751 162.0 3.1e-39
NP_068764 (OMIM: 611697) solute carrier family 22 ( 405) 751 162.0 3.1e-39
XP_016866671 (OMIM: 611697) PREDICTED: solute carr ( 389) 682 148.0 4.9e-35
XP_016866673 (OMIM: 611697) PREDICTED: solute carr ( 371) 640 139.5 1.7e-32
NP_001273385 (OMIM: 611697) solute carrier family ( 361) 417 94.3 7e-19
NP_695009 (OMIM: 607582) solute carrier family 22 ( 506) 379 86.7 1.9e-16
NP_695010 (OMIM: 607582) solute carrier family 22 ( 519) 379 86.7 1.9e-16
NP_695008 (OMIM: 607582) solute carrier family 22 ( 550) 379 86.7 2e-16
NP_004781 (OMIM: 607582) solute carrier family 22 ( 563) 379 86.7 2e-16
XP_016874051 (OMIM: 607582) PREDICTED: solute carr ( 551) 371 85.1 6.1e-16
NP_068812 (OMIM: 604842) solute carrier family 22 ( 556) 368 84.5 9.4e-16
NP_001171662 (OMIM: 607581) solute carrier family ( 451) 362 83.2 1.9e-15
NP_004245 (OMIM: 607581) solute carrier family 22 ( 542) 362 83.3 2.1e-15
NP_001171661 (OMIM: 607581) solute carrier family ( 542) 362 83.3 2.1e-15
XP_005267164 (OMIM: 604842) PREDICTED: solute carr ( 337) 355 81.7 4e-15
XP_005267163 (OMIM: 604842) PREDICTED: solute carr ( 425) 341 78.9 3.4e-14
XP_016873188 (OMIM: 607580) PREDICTED: solute carr ( 489) 340 78.8 4.4e-14
XP_011543318 (OMIM: 607580) PREDICTED: solute carr ( 541) 340 78.8 4.7e-14
NP_001034841 (OMIM: 607580) solute carrier family ( 541) 340 78.8 4.7e-14
XP_016873176 (OMIM: 610792) PREDICTED: solute carr ( 547) 339 78.6 5.5e-14
NP_955384 (OMIM: 610792) solute carrier family 22 ( 547) 339 78.6 5.5e-14
XP_016872648 (OMIM: 607579) PREDICTED: solute carr ( 445) 336 77.9 7.2e-14
NP_543142 (OMIM: 607579) solute carrier family 22 ( 553) 336 78.0 8.4e-14
XP_011534507 (OMIM: 608276) PREDICTED: solute carr ( 515) 331 77.0 1.6e-13
XP_011534506 (OMIM: 608276) PREDICTED: solute carr ( 534) 331 77.0 1.7e-13
NP_149116 (OMIM: 608276) solute carrier family 22 ( 577) 331 77.0 1.8e-13
NP_001129978 (OMIM: 611698) solute carrier family ( 552) 320 74.7 8e-13
NP_653186 (OMIM: 220150,607096) solute carrier fam ( 553) 315 73.7 1.6e-12
NP_060954 (OMIM: 607097) solute carrier family 22 ( 550) 310 72.7 3.2e-12
XP_016866692 (OMIM: 604842) PREDICTED: solute carr ( 404) 305 71.6 5.2e-12
XP_011534378 (OMIM: 604842) PREDICTED: solute carr ( 404) 305 71.6 5.2e-12
XP_011534377 (OMIM: 604842) PREDICTED: solute carr ( 404) 305 71.6 5.2e-12
NP_004247 (OMIM: 604047) solute carrier family 22 ( 551) 305 71.7 6.6e-12
XP_006715615 (OMIM: 602607) PREDICTED: solute carr ( 483) 304 71.5 6.8e-12
NP_694857 (OMIM: 602607) solute carrier family 22 ( 506) 304 71.5 7.1e-12
NP_696961 (OMIM: 604995) solute carrier family 22 ( 548) 304 71.5 7.5e-12
NP_003048 (OMIM: 602607) solute carrier family 22 ( 554) 304 71.5 7.6e-12
XP_005267160 (OMIM: 602607) PREDICTED: solute carr ( 573) 304 71.5 7.8e-12
>>XP_005267804 (OMIM: 611461) PREDICTED: solute carrier (538 aa)
initn: 3645 init1: 3645 opt: 3645 Z-score: 3995.0 bits: 748.9 E(85289): 8.7e-216
Smith-Waterman score: 3645; 100.0% identity (100.0% similar) in 538 aa overlap (1-538:1-538)
10 20 30 40 50 60
pF1KB4 MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 RFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA
430 440 450 460 470 480
490 500 510 520 530
pF1KB4 ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL
490 500 510 520 530
>>NP_065105 (OMIM: 611461) solute carrier family 22 memb (538 aa)
initn: 3645 init1: 3645 opt: 3645 Z-score: 3995.0 bits: 748.9 E(85289): 8.7e-216
Smith-Waterman score: 3645; 100.0% identity (100.0% similar) in 538 aa overlap (1-538:1-538)
10 20 30 40 50 60
pF1KB4 MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 RFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA
430 440 450 460 470 480
490 500 510 520 530
pF1KB4 ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL
490 500 510 520 530
>>XP_016876850 (OMIM: 611461) PREDICTED: solute carrier (538 aa)
initn: 3645 init1: 3645 opt: 3645 Z-score: 3995.0 bits: 748.9 E(85289): 8.7e-216
Smith-Waterman score: 3645; 100.0% identity (100.0% similar) in 538 aa overlap (1-538:1-538)
10 20 30 40 50 60
pF1KB4 MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 RFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA
430 440 450 460 470 480
490 500 510 520 530
pF1KB4 ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL
490 500 510 520 530
>>NP_057693 (OMIM: 611461) solute carrier family 22 memb (520 aa)
initn: 3478 init1: 2634 opt: 2634 Z-score: 2887.3 bits: 543.9 E(85289): 4.4e-154
Smith-Waterman score: 3443; 96.5% identity (96.5% similar) in 538 aa overlap (1-538:1-520)
10 20 30 40 50 60
pF1KB4 MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 RFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGL
::::::::::::::::::::::::::: ::::::::::::::
NP_057 RFGRRGILLLSMTLTGIASLVLLGLWDY------------------LNEAAITTFSVLGL
370 380 390 400
430 440 450 460 470 480
pF1KB4 FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA
410 420 430 440 450 460
490 500 510 520 530
pF1KB4 ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL
470 480 490 500 510 520
>>XP_016876851 (OMIM: 611461) PREDICTED: solute carrier (520 aa)
initn: 3478 init1: 2634 opt: 2634 Z-score: 2887.3 bits: 543.9 E(85289): 4.4e-154
Smith-Waterman score: 3443; 96.5% identity (96.5% similar) in 538 aa overlap (1-538:1-520)
10 20 30 40 50 60
pF1KB4 MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 RFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGL
::::::::::::::::::::::::::: ::::::::::::::
XP_016 RFGRRGILLLSMTLTGIASLVLLGLWDY------------------LNEAAITTFSVLGL
370 380 390 400
430 440 450 460 470 480
pF1KB4 FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA
410 420 430 440 450 460
490 500 510 520 530
pF1KB4 ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL
470 480 490 500 510 520
>>XP_005267805 (OMIM: 611461) PREDICTED: solute carrier (412 aa)
initn: 1924 init1: 1924 opt: 1931 Z-score: 2118.3 bits: 401.3 E(85289): 3e-111
Smith-Waterman score: 2515; 76.6% identity (76.6% similar) in 538 aa overlap (1-538:1-412)
10 20 30 40 50 60
pF1KB4 MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN
:::::::::::::::::::::::::::::::::::::::::
XP_005 RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDL-------------------
250 260 270 280
310 320 330 340 350 360
pF1KB4 YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD
XP_005 ------------------------------------------------------------
370 380 390 400 410 420
pF1KB4 RFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGL
:::::::::::::
XP_005 -----------------------------------------------NEAAITTFSVLGL
290
430 440 450 460 470 480
pF1KB4 FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA
300 310 320 330 340 350
490 500 510 520 530
pF1KB4 ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL
360 370 380 390 400 410
>>NP_001275979 (OMIM: 611461) solute carrier family 22 m (302 aa)
initn: 1978 init1: 1134 opt: 1134 Z-score: 1246.7 bits: 239.6 E(85289): 1.1e-62
Smith-Waterman score: 1943; 94.1% identity (94.1% similar) in 320 aa overlap (219-538:1-302)
190 200 210 220 230 240
pF1KB4 ALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQ
::::::::::::::::::::::::::::::
NP_001 MITAPCILFLFYGWPGLFLESARWLIVKRQ
10 20 30
250 260 270 280 290 300
pF1KB4 IEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKNL
40 50 60 70 80 90
310 320 330 340 350 360
pF1KB4 LILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGIL
100 110 120 130 140 150
370 380 390 400 410 420
pF1KB4 LLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGLFSSQAAAI
::::::::::::::::::: ::::::::::::::::::::::
NP_001 LLSMTLTGIASLVLLGLWDY------------------LNEAAITTFSVLGLFSSQAAAI
160 170 180 190
430 440 450 460 470 480
pF1KB4 LSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCIL
200 210 220 230 240 250
490 500 510 520 530
pF1KB4 SIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL
260 270 280 290 300
>>NP_056297 (OMIM: 611697) solute carrier family 22 memb (686 aa)
initn: 945 init1: 402 opt: 936 Z-score: 1025.0 bits: 199.7 E(85289): 2.4e-50
Smith-Waterman score: 936; 32.9% identity (64.5% similar) in 529 aa overlap (23-533:148-654)
10 20 30 40 50
pF1KB4 MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVA
. ..: . :.. ... : . . : :
NP_056 SFLLDQPNFWCRGAGKGTELAGVTTTGRGGDMGNWTSLPTTPFATAPWEAAGNRSNSSGA
120 130 140 150 160 170
60 70 80 90 100
pF1KB4 TSTD-PSCSGFAPPD----FNHC-LKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQIL
. : : .::: ..: . :::. :. :....:::::: .:.: . ..
NP_056 DGGDTPPLP--SPPDKGDNASNCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFS
180 190 200 210 220 230
110 120 130 140 150 160
pF1KB4 FILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLA
...:. :::. : :: ::: ..:... .. :. : . . : .:::. :: ::
NP_056 LLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLA
240 250 260 270 280 290
170 180 190 200 210 220
pF1KB4 GVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCIL
:. : .: .:.::: : .:. ..... .:...:.::. ::: . .::. :: .: : .:
NP_056 GIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLL
300 310 320 330 340 350
230 240 250 260 270 280
pF1KB4 FLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERNR--PHGQMLGEEAQEALQDLENT
.:.: : ..: :: :::.. .:.: :. .. ....:: :.:.. : .. .::.
NP_056 MLLY-W-SIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKG-----VIPELEKE
360 370 380 390 400
290 300 310 320 330
pF1KB4 CPLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGS---P--SDFYL
.. ...... ::.:::...: ... ...:.::. : : .::
NP_056 LSR-RPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYA
410 420 430 440 450 460
340 350 360 370 380 390
pF1KB4 CSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWD-----CEHPIFP
... : ..:. . :.: .:::: ::: : ::..:::. ::: . .::
NP_056 DYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHP---
470 480 490 500 510 520
400 410 420 430 440 450
pF1KB4 TVWAQQGNPNRDLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALG
..: . .. .:. ::..:.:.:.:.. ::... ::. ::..: ::::..: .
NP_056 ----DSGMSDSVKDKFSIA-FSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASA
530 540 550 560 570
460 470 480 490 500 510
pF1KB4 ALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRDGELCRRP
..: :..: .:: .: ::.:...: :.:.::. :.::::.. . ::: . .:: :
NP_056 GFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQ
580 590 600 610 620 630
520 530
pF1KB4 SLLRQPPPTRCDHVPLLATPNPAL
:: : . . ::: :
NP_056 PLL----PHKKGEQPLLLTNAELKDYSGLHDAAAAGDTLPEGATANGMKAM
640 650 660 670 680
>>XP_016866669 (OMIM: 611697) PREDICTED: solute carrier (512 aa)
initn: 908 init1: 365 opt: 895 Z-score: 981.8 bits: 191.3 E(85289): 6e-48
Smith-Waterman score: 895; 33.5% identity (64.9% similar) in 493 aa overlap (57-533:8-480)
30 40 50 60 70 80
pF1KB4 WEQPPNASGVSVASAALAASAASRVATSTDPSCSGFAPPDFNHCLKDWDYNGLPVLTTNA
:: . . :. : .. . ..:: : .
XP_016 MPVGPQHPSFKRSSLDTFHGCCQQQETGALPWDTDTK
10 20 30
90 100 110 120 130 140
pF1KB4 IGQ----WDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCG
. :::::: .:.: . .. ...:. :::. : :: ::: ..:... .. :
XP_016 RWRPELNWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFG
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB4 VGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFL
. : . . : .:::. :: :::. : .: .:.::: : .:. ..... .:...:.::
XP_016 LTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFL
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB4 FLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAER
. ::: . .::. :: .: : .:.:.: : ..: :: :::.. .:.: :. .. ....
XP_016 MPGLAALCRDWQVLQALIICPFLLMLLY-W-SIFPESLRWLMATQQFESAKRLILHFTQK
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB4 NR--PHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHA
:: :.:.. : .. .::. .. ...... ::.:::...: ... ...
XP_016 NRMNPEGDIKG-----VIPELEKELSR-RPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYG
220 230 240 250 260
330 340 350 360 370
pF1KB4 IRHCYQPVGGGGS---P--SDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLT
:.::. : : .:: ... : ..:. . :.: .:::: ::: : ::
XP_016 IHHCFARSMMGHEVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILT
270 280 290 300 310 320
380 390 400 410 420 430
pF1KB4 GIASLVLLGLWD-----CEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGLFSSQAAAILS
..:::. ::: . .:: ..: . .. .:. ::..:.:.:.:.. ::
XP_016 ALASLLQLGLLNLIGKYSQHP-------DSGMSDSVKDKFSIA-FSIVGMFASHAVGSLS
330 340 350 360 370 380
440 450 460 470 480 490
pF1KB4 TLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSI
... ::. ::..: ::::..: ...: :..: .:: .: ::.:...: :.:.::. :
XP_016 VFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICI
390 400 410 420 430 440
500 510 520 530
pF1KB4 MLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL
.::::.. . ::: . .:: : :: : . . ::: :
XP_016 LLLPESRDQNLPENISNGEHYTRQPLL----PHKKGEQPLLLTNAELKDYSGLHDAAAAG
450 460 470 480 490
XP_016 DTLPEGATANGMKAM
500 510
>>XP_011513103 (OMIM: 611697) PREDICTED: solute carrier (710 aa)
initn: 908 init1: 365 opt: 889 Z-score: 973.3 bits: 190.2 E(85289): 1.8e-47
Smith-Waterman score: 892; 31.7% identity (63.5% similar) in 540 aa overlap (21-533:159-678)
10 20 30 40
pF1KB4 MASDPIFTLAPPLHCHYGAFPPNASGWEQP---PNASGVSVASAALAASA
: .. :: :.::.. ... :
XP_011 RGAGKGTELAGVTTTGRGGDMGNWTSLPTTPFATAPWEAAGNRSNSSGADGGDTPPLPSP
130 140 150 160 170 180
50 60 70 80 90
pF1KB4 ASRVATSTDPSC--------SGFAPPDFNHCLKDWDYNGLPVLTTNAIGQ----WDLVCD
.. .... .: .:.. ..: .. . ..:: : . . ::::::
XP_011 PDKGDNASNCDCRAWDYGIRAGLVQNVVSKCCQQQETGALPWDTDTKRWRPELNWDLVCD
190 200 210 220 230 240
100 110 120 130 140 150
pF1KB4 LGWQVILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVM
.:.: . .. ...:. :::. : :: ::: ..:... .. :. : . . :
XP_011 NAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFS
250 260 270 280 290 300
160 170 180 190 200 210
pF1KB4 ALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRF
.:::. :: :::. : .: .:.::: : .:. ..... .:...:.::. ::: . .::.
XP_011 TLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQV
310 320 330 340 350 360
220 230 240 250 260 270
pF1KB4 LQRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERNR--PHGQMLGEE
:: .: : .:.:.: : ..: :: :::.. .:.: :. .. ....:: :.:.. :
XP_011 LQALIICPFLLMLLY-W-SIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKG--
370 380 390 400 410 420
280 290 300 310 320 330
pF1KB4 AQEALQDLENTCPLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGS
.. .::. .. ...... ::.:::...: ... ...:.::. :
XP_011 ---VIPELEKELSR-RPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHE
430 440 450 460 470 480
340 350 360 370 380
pF1KB4 ---P--SDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWD-
: .:: ... : ..:. . :.: .:::: ::: : ::..:::. ::: .
XP_011 VKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNL
490 500 510 520 530 540
390 400 410 420 430 440
pF1KB4 ----CEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVR
.:: ..: . .. .:. ::..:.:.:.:.. ::... ::. ::..:
XP_011 IGKYSQHP-------DSGMSDSVKDKFSIA-FSIVGMFASHAVGSLSVFFCAEITPTVIR
550 560 570 580 590
450 460 470 480 490 500
pF1KB4 GRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPE
::::..: ...: :..: .:: .: ::.:...: :.:.::. :.::::.. . :::
XP_011 CGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPE
600 610 620 630 640 650
510 520 530
pF1KB4 VLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL
. .:: : :: : . . ::: :
XP_011 NISNGEHYTRQPLL----PHKKGEQPLLLTNAELKDYSGLHDAAAAGDTLPEGATANGMK
660 670 680 690 700
538 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 05:47:46 2016 done: Sat Nov 5 05:47:47 2016
Total Scan time: 11.290 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]