Result of FASTA (omim) for
pF1KB4286
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4286, 235 aa
1>>>pF1KB4286 235 - 235 aa - 235 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9545+/-0.000405; mu= 16.9597+/- 0.025
mean_var=74.1594+/-15.181, 0's: 0 Z-trim(112.4): 20 B-trim: 70 in 1/46
Lambda= 0.148933
statistics sampled from 21226 (21245) to 21226 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.249), width: 16
Scan time: 6.080
The best scores are: opt bits E(85289)
NP_852006 (OMIM: 605214) calcium-activated potassi ( 235) 1581 348.8 4.6e-96
XP_011510627 (OMIM: 605214) PREDICTED: calcium-act ( 235) 1581 348.8 4.6e-96
NP_005823 (OMIM: 605214) calcium-activated potassi ( 235) 1581 348.8 4.6e-96
NP_001265840 (OMIM: 605214) calcium-activated pota ( 235) 1581 348.8 4.6e-96
NP_741979 (OMIM: 605222) calcium-activated potassi ( 277) 636 145.9 6.9e-35
NP_741980 (OMIM: 605222) calcium-activated potassi ( 257) 633 145.2 1e-34
NP_741981 (OMIM: 605222) calcium-activated potassi ( 275) 633 145.2 1.1e-34
NP_055222 (OMIM: 605222) calcium-activated potassi ( 279) 633 145.2 1.1e-34
NP_004128 (OMIM: 603951,608622) calcium-activated ( 191) 534 123.8 2.1e-28
NP_055320 (OMIM: 605223) calcium-activated potassi ( 210) 419 99.1 6.1e-21
NP_001157149 (OMIM: 605222) calcium-activated pota ( 173) 381 90.9 1.5e-18
XP_011536490 (OMIM: 605223) PREDICTED: calcium-act ( 189) 346 83.4 3e-16
>>NP_852006 (OMIM: 605214) calcium-activated potassium c (235 aa)
initn: 1581 init1: 1581 opt: 1581 Z-score: 1845.6 bits: 348.8 E(85289): 4.6e-96
Smith-Waterman score: 1581; 100.0% identity (100.0% similar) in 235 aa overlap (1-235:1-235)
10 20 30 40 50 60
pF1KB4 MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 MYFLLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 MYFLLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 TSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 TSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEG
130 140 150 160 170 180
190 200 210 220 230
pF1KB4 NQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 NQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR
190 200 210 220 230
>>XP_011510627 (OMIM: 605214) PREDICTED: calcium-activat (235 aa)
initn: 1581 init1: 1581 opt: 1581 Z-score: 1845.6 bits: 348.8 E(85289): 4.6e-96
Smith-Waterman score: 1581; 100.0% identity (100.0% similar) in 235 aa overlap (1-235:1-235)
10 20 30 40 50 60
pF1KB4 MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 MYFLLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MYFLLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 TSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEG
130 140 150 160 170 180
190 200 210 220 230
pF1KB4 NQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR
190 200 210 220 230
>>NP_005823 (OMIM: 605214) calcium-activated potassium c (235 aa)
initn: 1581 init1: 1581 opt: 1581 Z-score: 1845.6 bits: 348.8 E(85289): 4.6e-96
Smith-Waterman score: 1581; 100.0% identity (100.0% similar) in 235 aa overlap (1-235:1-235)
10 20 30 40 50 60
pF1KB4 MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 MYFLLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MYFLLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 TSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEG
130 140 150 160 170 180
190 200 210 220 230
pF1KB4 NQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR
190 200 210 220 230
>>NP_001265840 (OMIM: 605214) calcium-activated potassiu (235 aa)
initn: 1581 init1: 1581 opt: 1581 Z-score: 1845.6 bits: 348.8 E(85289): 4.6e-96
Smith-Waterman score: 1581; 100.0% identity (100.0% similar) in 235 aa overlap (1-235:1-235)
10 20 30 40 50 60
pF1KB4 MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 MYFLLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYFLLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 TSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEG
130 140 150 160 170 180
190 200 210 220 230
pF1KB4 NQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR
190 200 210 220 230
>>NP_741979 (OMIM: 605222) calcium-activated potassium c (277 aa)
initn: 593 init1: 224 opt: 636 Z-score: 747.3 bits: 145.9 E(85289): 6.9e-35
Smith-Waterman score: 636; 41.8% identity (72.0% similar) in 232 aa overlap (7-235:20-247)
10 20 30 40
pF1KB4 MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRA
:::. .... :. : : :: .: . . .::::::
NP_741 MQPFSIPVQITLQGSRRRQGRTAFPASGKKRETDYS---DGDPLDVHKRLPS-SAGEDRA
10 20 30 40 50
50 60 70 80 90 100
pF1KB4 ILLGLAMMVCSIMMYFLLGITLLRSYMQSVWTEESQCTLLNASITETF-NCSFSCGPDCW
..::.::: :..:.:::: :.:. .: :. ::: :: ....: . . .:.:.:: :
NP_741 VMLGFAMMGFSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCH
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB4 KLSQYPCLQVYVNLTSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENF
..::::::.:::. :.: ::...::...:: :: : ::: .. .. .. . . : :
NP_741 GQGKYPCLQVFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFF
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB4 --RKYQHFSCYSDPEGNQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLS
.. :::. .: .....::: : :.. ..:: ::::. . ::. ::.::.:::.::
NP_741 DHKNGTPFSCFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLS
180 190 200 210 220 230
230
pF1KB4 LLCERIQRINR
::::. . . :
NP_741 LLCEKYSTVVRDEVGGKVPYIEQHQFKLCIMRRSKGRAEKS
240 250 260 270
>>NP_741980 (OMIM: 605222) calcium-activated potassium c (257 aa)
initn: 593 init1: 224 opt: 633 Z-score: 744.3 bits: 145.2 E(85289): 1e-34
Smith-Waterman score: 633; 43.9% identity (74.1% similar) in 212 aa overlap (27-235:17-227)
10 20 30 40 50 60
pF1KB4 MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIM
: : :: .: . . .::::::..::.::: :..
NP_741 MTAFPASGKKRETDYSDGDPLDVHKRLPS-SAGEDRAVMLGFAMMGFSVL
10 20 30 40
70 80 90 100 110
pF1KB4 MYFLLGITLLRSYMQSVWTEESQCTLLNASITETF-NCSFSCGPDCWKLSQYPCLQVYVN
:.:::: :.:. .: :. ::: :: ....: . . .:.:.:: : ..::::::.::
NP_741 MFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVN
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB4 LTSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENF--RKYQHFSCYSD
:. :.: ::...::...:: :: : ::: .. .. .. . . : : .. :::. .
NP_741 LSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB4 PEGNQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR
: .....::: : :.. ..:: ::::. . ::. ::.::.:::.::::::. . . :
NP_741 PASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDE
170 180 190 200 210 220
NP_741 VGGKVPYIEQHQFKLCIMRRSKGRAEKS
230 240 250
>>NP_741981 (OMIM: 605222) calcium-activated potassium c (275 aa)
initn: 593 init1: 224 opt: 633 Z-score: 743.9 bits: 145.2 E(85289): 1.1e-34
Smith-Waterman score: 633; 43.9% identity (74.1% similar) in 212 aa overlap (27-235:35-245)
10 20 30 40 50
pF1KB4 MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMV
: : :: .: . . .::::::..::.:::
NP_741 LYELTAVSPSPFPQRTAFPASGKKRETDYSDGDPLDVHKRLPS-SAGEDRAVMLGFAMMG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 CSIMMYFLLGITLLRSYMQSVWTEESQCTLLNASITETF-NCSFSCGPDCWKLSQYPCLQ
:..:.:::: :.:. .: :. ::: :: ....: . . .:.:.:: : ..:::::
NP_741 FSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB4 VYVNLTSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENF--RKYQHFS
:.:::. :.: ::...::...:: :: : ::: .. .. .. . . : : .. ::
NP_741 VFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB4 CYSDPEGNQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRI
:. .: .....::: : :.. ..:: ::::. . ::. ::.::.:::.::::::. . .
NP_741 CFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTV
190 200 210 220 230 240
pF1KB4 NR
:
NP_741 VRDEVGGKVPYIEQHQFKLCIMRRSKGRAEKS
250 260 270
>>NP_055222 (OMIM: 605222) calcium-activated potassium c (279 aa)
initn: 593 init1: 224 opt: 633 Z-score: 743.8 bits: 145.2 E(85289): 1.1e-34
Smith-Waterman score: 633; 43.9% identity (74.1% similar) in 212 aa overlap (27-235:39-249)
10 20 30 40 50
pF1KB4 MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMV
: : :: .: . . .::::::..::.:::
NP_055 LGFHFVAFILLTRHRTAFPASGKKRETDYSDGDPLDVHKRLPS-SAGEDRAVMLGFAMMG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 CSIMMYFLLGITLLRSYMQSVWTEESQCTLLNASITETF-NCSFSCGPDCWKLSQYPCLQ
:..:.:::: :.:. .: :. ::: :: ....: . . .:.:.:: : ..:::::
NP_055 FSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB4 VYVNLTSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENF--RKYQHFS
:.:::. :.: ::...::...:: :: : ::: .. .. .. . . : : .. ::
NP_055 VFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB4 CYSDPEGNQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRI
:. .: .....::: : :.. ..:: ::::. . ::. ::.::.:::.::::::. . .
NP_055 CFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTV
190 200 210 220 230 240
pF1KB4 NR
:
NP_055 VRDEVGGKVPYIEQHQFKLCIMRRSKGRAEKS
250 260 270
>>NP_004128 (OMIM: 603951,608622) calcium-activated pota (191 aa)
initn: 532 init1: 339 opt: 534 Z-score: 631.0 bits: 123.8 E(85289): 2.1e-28
Smith-Waterman score: 534; 43.5% identity (73.1% similar) in 193 aa overlap (34-226:3-187)
10 20 30 40 50 60
pF1KB4 WTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIMMYF
.: : : : :: ::. ::..:.::... :.
NP_004 MVKKLVMAQKRGETRALCLGVTMVVCAVITYY
10 20 30
70 80 90 100 110 120
pF1KB4 LLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSS
.: :.: :..::::.::.: :....: . . . : :. ::::: .::....
NP_004 ILVTTVLPLYQKSVWTQESKCHLIETNIRDQEELK---GK---KVPQYPCL--WVNVSAA
40 50 60 70 80
130 140 150 160 170 180
pF1KB4 GEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEGNQK
:. .:::::.: ::.::::: :.. . . :. : .:.. : : :.: :.::.
NP_004 GRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQVFYCFSAPRGNET
90 100 110 120 130 140
190 200 210 220 230
pF1KB4 SVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR
::.. .::. ..:. :::::: ...::. :.:::: .::::.:
NP_004 SVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK
150 160 170 180 190
>>NP_055320 (OMIM: 605223) calcium-activated potassium c (210 aa)
initn: 332 init1: 243 opt: 419 Z-score: 496.9 bits: 99.1 E(85289): 6.1e-21
Smith-Waterman score: 419; 32.4% identity (65.2% similar) in 210 aa overlap (31-232:1-206)
10 20 30 40 50 60
pF1KB4 MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIM
. : ... .::..: ::: ... ...
NP_055 MAKLRVAYEYTEAEDKSIRLGLFLIISGVV
10 20 30
70 80 90 100 110
pF1KB4 MYFLLGITLLRSYMQSVWTEESQCTLLNAS-ITETFNCSFSCGPDCWKLSQYPCLQVYVN
:..:. : .:.. . :..::.:... : :.:.:.:.:: :: :::::.:::::
NP_055 SLFIFGFCWLSPALQDLQATEANCTVLSVQQIGEVFECTFTCGADCRGTSQYPCVQVYVN
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB4 LTSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKY-------QHF
. :. . ::. :. . : :::::: : . :... .. :: :...: : :
NP_055 NSESNSRALLHSDEHQLLTNPKCSYIPPCKR---ENQKNLESVM-NWQQYWKDEIGSQPF
100 110 120 130 140
180 190 200 210 220 230
pF1KB4 SCYSDPEGNQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQR
.:: . . .:.: . .. ::.: ..:: .. :: ::... .. :.. : ...
NP_055 TCYFNQHQRPDDVLLHRTHDEIVLLHCFLWPLVTFVVGVLIVVLTICAKSLAVKAEAMKK
150 160 170 180 190 200
pF1KB4 INR
NP_055 RKFS
210
235 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 05:46:35 2016 done: Sat Nov 5 05:46:36 2016
Total Scan time: 6.080 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]