Result of FASTA (omim) for
pF1KB4237
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4237, 817 aa
1>>>pF1KB4237 817 - 817 aa - 817 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.2815+/-0.000473; mu= 8.2731+/- 0.029
mean_var=277.1918+/-61.633, 0's: 0 Z-trim(118.1): 385 B-trim: 1440 in 2/54
Lambda= 0.077034
statistics sampled from 30268 (30800) to 30268 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.361), width: 16
Scan time: 13.310
The best scores are: opt bits E(85289)
NP_066943 (OMIM: 300189,300850) disks large homolo ( 817) 5527 628.8 2.9e-179
XP_006724689 (OMIM: 300189,300850) PREDICTED: disk ( 831) 4133 473.9 1.3e-132
XP_011529185 (OMIM: 300189,300850) PREDICTED: disk ( 835) 4012 460.5 1.4e-128
XP_006724688 (OMIM: 300189,300850) PREDICTED: disk ( 849) 4012 460.5 1.4e-128
XP_016884813 (OMIM: 300189,300850) PREDICTED: disk ( 480) 2884 334.8 5.5e-91
NP_001136172 (OMIM: 603583) disks large homolog 2 ( 749) 2420 283.5 2.4e-75
XP_011543090 (OMIM: 603583) PREDICTED: disks large ( 767) 2420 283.5 2.5e-75
XP_016872774 (OMIM: 603583) PREDICTED: disks large ( 796) 2420 283.5 2.5e-75
XP_016872772 (OMIM: 603583) PREDICTED: disks large ( 810) 2420 283.5 2.6e-75
XP_005273868 (OMIM: 603583) PREDICTED: disks large ( 819) 2420 283.5 2.6e-75
XP_016872770 (OMIM: 603583) PREDICTED: disks large ( 820) 2420 283.5 2.6e-75
XP_016872769 (OMIM: 603583) PREDICTED: disks large ( 820) 2420 283.5 2.6e-75
XP_016872768 (OMIM: 603583) PREDICTED: disks large ( 821) 2420 283.5 2.6e-75
XP_016872767 (OMIM: 603583) PREDICTED: disks large ( 839) 2420 283.5 2.6e-75
XP_016872765 (OMIM: 603583) PREDICTED: disks large ( 848) 2420 283.5 2.6e-75
NP_001287912 (OMIM: 603583) disks large homolog 2 ( 852) 2420 283.5 2.6e-75
XP_016872761 (OMIM: 603583) PREDICTED: disks large ( 871) 2420 283.5 2.7e-75
XP_016872760 (OMIM: 603583) PREDICTED: disks large ( 872) 2420 283.5 2.7e-75
XP_016872759 (OMIM: 603583) PREDICTED: disks large ( 873) 2420 283.5 2.7e-75
XP_016872755 (OMIM: 603583) PREDICTED: disks large ( 891) 2420 283.6 2.7e-75
XP_016872750 (OMIM: 603583) PREDICTED: disks large ( 955) 2420 283.6 2.8e-75
XP_016872749 (OMIM: 603583) PREDICTED: disks large ( 968) 2420 283.6 2.9e-75
XP_016872748 (OMIM: 603583) PREDICTED: disks large ( 969) 2420 283.6 2.9e-75
XP_011543082 (OMIM: 603583) PREDICTED: disks large (1007) 2420 283.6 2.9e-75
NP_001191317 (OMIM: 601014) disks large homolog 1 ( 788) 2381 279.2 5.1e-74
XP_016861311 (OMIM: 601014) PREDICTED: disks large ( 821) 2381 279.2 5.2e-74
XP_011510808 (OMIM: 601014) PREDICTED: disks large ( 853) 2381 279.2 5.3e-74
XP_016861309 (OMIM: 601014) PREDICTED: disks large ( 853) 2381 279.2 5.3e-74
XP_016861307 (OMIM: 601014) PREDICTED: disks large ( 871) 2381 279.2 5.4e-74
XP_016861305 (OMIM: 601014) PREDICTED: disks large ( 871) 2381 279.2 5.4e-74
XP_016861308 (OMIM: 601014) PREDICTED: disks large ( 871) 2381 279.2 5.4e-74
XP_011510807 (OMIM: 601014) PREDICTED: disks large ( 871) 2381 279.2 5.4e-74
XP_016861306 (OMIM: 601014) PREDICTED: disks large ( 871) 2381 279.2 5.4e-74
NP_001091894 (OMIM: 601014) disks large homolog 1 ( 904) 2381 279.2 5.5e-74
XP_016861294 (OMIM: 601014) PREDICTED: disks large ( 904) 2381 279.2 5.5e-74
XP_011510804 (OMIM: 601014) PREDICTED: disks large ( 904) 2381 279.2 5.5e-74
NP_001277912 (OMIM: 601014) disks large homolog 1 ( 904) 2381 279.2 5.5e-74
XP_016884816 (OMIM: 300189,300850) PREDICTED: disk ( 334) 2226 261.5 4.5e-69
NP_001308004 (OMIM: 602887) disks large homolog 4 ( 724) 2188 257.7 1.4e-67
NP_001356 (OMIM: 602887) disks large homolog 4 iso ( 767) 2188 257.7 1.4e-67
XP_016879777 (OMIM: 602887) PREDICTED: disks large ( 702) 2185 257.3 1.7e-67
NP_001122299 (OMIM: 602887) disks large homolog 4 ( 721) 2179 256.7 2.7e-67
NP_001308003 (OMIM: 602887) disks large homolog 4 ( 764) 2179 256.7 2.8e-67
XP_016879779 (OMIM: 602887) PREDICTED: disks large ( 697) 2176 256.3 3.4e-67
XP_016879778 (OMIM: 602887) PREDICTED: disks large ( 699) 2176 256.3 3.4e-67
XP_005256548 (OMIM: 602887) PREDICTED: disks large ( 754) 2176 256.4 3.6e-67
XP_011522000 (OMIM: 602887) PREDICTED: disks large ( 797) 2176 256.4 3.7e-67
XP_011522001 (OMIM: 602887) PREDICTED: disks large ( 797) 2176 256.4 3.7e-67
XP_011522004 (OMIM: 602887) PREDICTED: disks large ( 664) 2146 253.0 3.3e-66
NP_001308006 (OMIM: 602887) disks large homolog 4 ( 664) 2146 253.0 3.3e-66
>>NP_066943 (OMIM: 300189,300850) disks large homolog 3 (817 aa)
initn: 5527 init1: 5527 opt: 5527 Z-score: 3339.3 bits: 628.8 E(85289): 2.9e-179
Smith-Waterman score: 5527; 100.0% identity (100.0% similar) in 817 aa overlap (1-817:1-817)
10 20 30 40 50 60
pF1KB4 MHKHQHCCKCPECYEVTRLAALRRLEPPGYGDWQVPDPYGPGGGNGASAGYGGYSSQTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MHKHQHCCKCPECYEVTRLAALRRLEPPGYGDWQVPDPYGPGGGNGASAGYGGYSSQTLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 SQAGATPTPRTKAKLIPTGRDVGPVPPKPVPGKSTPKLNGSGPSWWPECTCTNRDWYEQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 SQAGATPTPRTKAKLIPTGRDVGPVPPKPVPGKSTPKLNGSGPSWWPECTCTNRDWYEQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 NGSDGMFKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 NGSDGMFKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 DCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLVVRRRQPPPETIMEVNLLKGPKGLGFSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 DCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLVVRRRQPPPETIMEVNLLKGPKGLGFSI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 AGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 AGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TSDMVYLKVAKPGSLHLNDMYAPPDYASTFTALADNHISHNSSLGYLGAVESKVSYPAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 TSDMVYLKVAKPGSLHLNDMYAPPDYASTFTALADNHISHNSSLGYLGAVESKVSYPAPP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 QVPPTRYSPIPRHMLAEEDFTREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 QVPPTRYSPIPRHMLAEEDFTREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 DLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 DLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 REQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 REQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 DEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPGLSDDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 DEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPGLSDDY
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 YGAKNLKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 YGAKNLKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 RPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 RPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 LDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEY
730 740 750 760 770 780
790 800 810
pF1KB4 FTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL
:::::::::::::::::::::::::::::::::::::
NP_066 FTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL
790 800 810
>>XP_006724689 (OMIM: 300189,300850) PREDICTED: disks la (831 aa)
initn: 4133 init1: 4133 opt: 4133 Z-score: 2502.0 bits: 473.9 E(85289): 1.3e-132
Smith-Waterman score: 5489; 98.3% identity (98.3% similar) in 831 aa overlap (1-817:1-831)
10 20 30 40 50 60
pF1KB4 MHKHQHCCKCPECYEVTRLAALRRLEPPGYGDWQVPDPYGPGGGNGASAGYGGYSSQTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MHKHQHCCKCPECYEVTRLAALRRLEPPGYGDWQVPDPYGPGGGNGASAGYGGYSSQTLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 SQAGATPTPRTKAKLIPTGRDVGPVPPKPVPGKSTPKLNGSGPSWWPECTCTNRDWYEQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQAGATPTPRTKAKLIPTGRDVGPVPPKPVPGKSTPKLNGSGPSWWPECTCTNRDWYEQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 NGSDGMFKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGSDGMFKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 DCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLVVRRRQPPPETIMEVNLLKGPKGLGFSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLVVRRRQPPPETIMEVNLLKGPKGLGFSI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 AGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TSDMVYLKVAKPGSLHLNDMYAPPDYASTFTALADNHISHNSSLGYLGAVESKVSYPAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TSDMVYLKVAKPGSLHLNDMYAPPDYASTFTALADNHISHNSSLGYLGAVESKVSYPAPP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 QVPPTRYSPIPRHMLAEEDFTREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVPPTRYSPIPRHMLAEEDFTREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 DLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 REQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 REQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 DEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPGLSDDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPGLSDDY
550 560 570 580 590 600
610 620 630 640
pF1KB4 YGAKNLKG--------------QEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLIS
:::::::: ::::::::::::::::::::::::::::::::::::::
XP_006 YGAKNLKGVTSNTSDSESSSKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLIS
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB4 EFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSI
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB4 QSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKI
730 740 750 760 770 780
770 780 790 800 810
pF1KB4 YDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL
790 800 810 820 830
>>XP_011529185 (OMIM: 300189,300850) PREDICTED: disks la (835 aa)
initn: 5402 init1: 4012 opt: 4012 Z-score: 2429.3 bits: 460.5 E(85289): 1.4e-128
Smith-Waterman score: 5371; 96.5% identity (97.2% similar) in 835 aa overlap (1-817:1-835)
10 20 30 40 50 60
pF1KB4 MHKHQHCCKCPECYEVTRLAALRRLEPPGYGDWQVPDPYGPGGGNGASAGYGGYSSQTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MHKHQHCCKCPECYEVTRLAALRRLEPPGYGDWQVPDPYGPGGGNGASAGYGGYSSQTLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 SQAGATPTPRTKAKLIPTGRDVGPVPPKPVPGKSTPKLNGSGPSWWPECTCTNRDWYEQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQAGATPTPRTKAKLIPTGRDVGPVPPKPVPGKSTPKLNGSGPSWWPECTCTNRDWYEQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 NGSDGMFKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGSDGMFKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 DCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLVVRRRQPPPETIMEVNLLKGPKGLGFSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLVVRRRQPPPETIMEVNLLKGPKGLGFSI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 AGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TSDMVYLKVAKPGSLHLNDMYAPPDYASTFTALADNHISHNSSLGYLGAVESKVSYPAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSDMVYLKVAKPGSLHLNDMYAPPDYASTFTALADNHISHNSSLGYLGAVESKVSYPAPP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 QVPPTRYSPIPRHMLAEEDFTREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVPPTRYSPIPRHMLAEEDFTREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 DLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 REQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASD
490 500 510 520 530 540
550 560 570 580 590
pF1KB4 DEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPG-----
:::::::::::::::::::::::::::::::::::::::::::::::::::..
XP_011 DEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRSIKTKRKKS
550 560 570 580 590 600
600 610 620 630 640
pF1KB4 --LSDDY--YGAK-NL--------KGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVND
:: . : .: :. .:::::::::::::::::::::::::::::::::::
XP_011 FRLSRKFPFYKSKENMAQESSIQEQGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVND
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB4 DLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLY
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB4 GTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQ
730 740 750 760 770 780
770 780 790 800 810
pF1KB4 ANKIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANKIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL
790 800 810 820 830
>>XP_006724688 (OMIM: 300189,300850) PREDICTED: disks la (849 aa)
initn: 5406 init1: 4012 opt: 4012 Z-score: 2429.2 bits: 460.5 E(85289): 1.4e-128
Smith-Waterman score: 5352; 94.8% identity (95.8% similar) in 849 aa overlap (1-817:1-849)
10 20 30 40 50 60
pF1KB4 MHKHQHCCKCPECYEVTRLAALRRLEPPGYGDWQVPDPYGPGGGNGASAGYGGYSSQTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MHKHQHCCKCPECYEVTRLAALRRLEPPGYGDWQVPDPYGPGGGNGASAGYGGYSSQTLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 SQAGATPTPRTKAKLIPTGRDVGPVPPKPVPGKSTPKLNGSGPSWWPECTCTNRDWYEQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQAGATPTPRTKAKLIPTGRDVGPVPPKPVPGKSTPKLNGSGPSWWPECTCTNRDWYEQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 NGSDGMFKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGSDGMFKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 DCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLVVRRRQPPPETIMEVNLLKGPKGLGFSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLVVRRRQPPPETIMEVNLLKGPKGLGFSI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 AGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TSDMVYLKVAKPGSLHLNDMYAPPDYASTFTALADNHISHNSSLGYLGAVESKVSYPAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TSDMVYLKVAKPGSLHLNDMYAPPDYASTFTALADNHISHNSSLGYLGAVESKVSYPAPP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 QVPPTRYSPIPRHMLAEEDFTREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVPPTRYSPIPRHMLAEEDFTREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 DLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 REQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 REQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASD
490 500 510 520 530 540
550 560 570 580 590
pF1KB4 DEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRD--------
:::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_006 DEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRSIKTKRKKS
550 560 570 580 590 600
600 610 620
pF1KB4 ------FP-----------------GLSDDYYGAKNL-KGQEDAILSYEPVTRQEIHYAR
:: :.... ... ::::::::::::::::::::::
XP_006 FRLSRKFPFYKSKENMAQESSIQEQGVTSNTSDSESSSKGQEDAILSYEPVTRQEIHYAR
610 620 630 640 650 660
630 640 650 660 670 680
pF1KB4 PVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQD
670 680 690 700 710 720
690 700 710 720 730 740
pF1KB4 NKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSI
730 740 750 760 770 780
750 760 770 780 790 800
pF1KB4 EALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHY
790 800 810 820 830 840
810
pF1KB4 IWVPSPEKL
:::::::::
XP_006 IWVPSPEKL
>>XP_016884813 (OMIM: 300189,300850) PREDICTED: disks la (480 aa)
initn: 2884 init1: 2884 opt: 2884 Z-score: 1754.5 bits: 334.8 E(85289): 5.5e-91
Smith-Waterman score: 2884; 100.0% identity (100.0% similar) in 436 aa overlap (382-817:45-480)
360 370 380 390 400 410
pF1KB4 SKVSYPAPPQVPPTRYSPIPRHMLAEEDFTREPRKIILHKGSTGLGFNIVGGEDGEGIFV
::::::::::::::::::::::::::::::
XP_016 GLGSASASAWRRASQRWAWPLRSLRPGGDAREPRKIILHKGSTGLGFNIVGGEDGEGIFV
20 30 40 50 60 70
420 430 440 450 460 470
pF1KB4 SFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYS
80 90 100 110 120 130
480 490 500 510 520 530
pF1KB4 RFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGD
140 150 160 170 180 190
540 550 560 570 580 590
pF1KB4 ILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNR
200 210 220 230 240 250
600 610 620 630 640 650
pF1KB4 DFPGLSDDYYGAKNLKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFPGLSDDYYGAKNLKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHK
260 270 280 290 300 310
660 670 680 690 700 710
pF1KB4 FGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRA
320 330 340 350 360 370
720 730 740 750 760 770
pF1KB4 VAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKAM
380 390 400 410 420 430
780 790 800 810
pF1KB4 KLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL
440 450 460 470 480
>>NP_001136172 (OMIM: 603583) disks large homolog 2 isof (749 aa)
initn: 3576 init1: 2420 opt: 2420 Z-score: 1473.6 bits: 283.5 E(85289): 2.4e-75
Smith-Waterman score: 3560; 72.6% identity (87.7% similar) in 733 aa overlap (108-817:24-749)
80 90 100 110 120 130
pF1KB4 TGRDVGPVPPKPVPGKSTPKLNGSGPSWWPECTCTNRDWYEQVNGSDGMFKYEEIVLERG
.: . . . :::.. ...:::.::::
NP_001 MQRPSVSRAENYQLLWDTIASLKQCEQAMQHAFIPVNGTEIEYEFEEITLERG
10 20 30 40 50
140 150 160 170 180 190
pF1KB4 NSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHS
::::::::::: ::::. ::::::::::::::::: :::: ::::.::::::::::: ::
NP_001 NSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHS
60 70 80 90 100 110
200 210 220 230 240 250
pF1KB4 RAVEALKEAGPVVRLVVRRRQPPPETIMEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYI
.::::::::: .::: ::::.: ::..:..:.:::::::::::::.::::::::::::.
NP_001 KAVEALKEAGSIVRLYVRRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYV
120 130 140 150 160 170
260 270 280 290 300 310
pF1KB4 TKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKVAKPGSLHL
::::.:::::::::::.::::: ::: .:..: :::::: :::::..:::::.:: ....
NP_001 TKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSEVVYLKVGKPTTIYM
180 190 200 210 220 230
320 330 340 350 360 370
pF1KB4 NDMYAPPDYASTFTALADNHISHNSSLGYLGAVESKVSYPAPPQVPPTRYSPIPRHMLAE
.: :.::: . ... .::. : :..: :.: :: . : ::::::.:::..
NP_001 TDPYGPPDITHSYSPPMENHLLS----GNNGTLEYKTSL--PP-ISPGRYSPIPKHMLVD
240 250 260 270 280
380 390 400 410
pF1KB4 EDFTR-----------------------EPRKIILHKGSTGLGFNIVGGEDGEGIFVSFI
.:.: ::::..::::::::::::::::::::::::::
NP_001 DDYTSHSQHSTATRQPSMTLQRAVSLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFI
290 300 310 320 330 340
420 430 440 450 460 470
pF1KB4 LAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFE
::::::::::::.:::.::::::..::.:.::::::::: :::.:::.:::.::.:.:::
NP_001 LAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFE
350 360 370 380 390 400
480 490 500 510 520 530
pF1KB4 SKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILH
.::::::::::: :::::::::::..::::::::.::::...:: ::::::::.::::::
NP_001 AKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILH
410 420 430 440 450 460
540 550 560 570 580 590
pF1KB4 VINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFP
::::::::::::: : .:.::..::::::.:::.:::::::::::.:. :.:.:. :.:
NP_001 VINASDDEWWQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIP
470 480 490 500 510 520
600 610 620 630 640 650
pF1KB4 GLSDDYYGAKNLKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGS
::.:: ::.:.:.:::: ::::::::::::.:.::::::::::::.::::::::: ::::
NP_001 GLGDDGYGTKTLRGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGS
530 540 550 560 570 580
660 670 680 690 700 710
pF1KB4 CVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAE
::::::::.:: ::::.:::::.::::::::::..:::::::.::::::::.:::: :::
NP_001 CVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAE
590 600 610 620 630 640
720 730 740 750 760 770
pF1KB4 RGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKAMKLE
:::::::::::::::::: ::::::::::::.:.: :::::.: : :::.: ::.:.:::
NP_001 RGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAIKLE
650 660 670 680 690 700
780 790 800 810
pF1KB4 QEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL
::::::::::::::.::.:::. : .::.::: .::.:: :::
NP_001 QEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL
710 720 730 740
>>XP_011543090 (OMIM: 603583) PREDICTED: disks large hom (767 aa)
initn: 3576 init1: 2420 opt: 2420 Z-score: 1473.5 bits: 283.5 E(85289): 2.5e-75
Smith-Waterman score: 3557; 73.3% identity (88.0% similar) in 726 aa overlap (115-817:49-767)
90 100 110 120 130 140
pF1KB4 VPPKPVPGKSTPKLNGSGPSWWPECTCTNRDWYEQVNGSDGMFKYEEIVLERGNSGLGFS
: :::.. ...:::.:::::::::::
XP_011 IASLKQCEQAMQHAFIPASPAPIIVNTDTLDTIPYVNGTEIEYEFEEITLERGNSGLGFS
20 30 40 50 60 70
150 160 170 180 190 200
pF1KB4 IAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALK
:::: ::::. ::::::::::::::::: :::: ::::.::::::::::: ::.::::::
XP_011 IAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALK
80 90 100 110 120 130
210 220 230 240 250 260
pF1KB4 EAGPVVRLVVRRRQPPPETIMEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGG
::: .::: ::::.: ::..:..:.:::::::::::::.::::::::::::.::::.::
XP_011 EAGSIVRLYVRRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGG
140 150 160 170 180 190
270 280 290 300 310 320
pF1KB4 AAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKVAKPGSLHLNDMYAPP
:::::::::.::::: ::: .:..: :::::: :::::..:::::.:: .....: :.::
XP_011 AAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSEVVYLKVGKPTTIYMTDPYGPP
200 210 220 230 240 250
330 340 350 360 370 380
pF1KB4 DYASTFTALADNHISHNSSLGYLGAVESKVSYPAPPQVPPTRYSPIPRHMLAEEDFTR--
: . ... .::. : :..: :.: : : . : ::::::.:::...:.:
XP_011 DITHSYSPPMENHLLS----GNNGTLEYKTSLP--P-ISPGRYSPIPKHMLVDDDYTSHS
260 270 280 290 300 310
390 400 410 420
pF1KB4 ---------------------EPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPAD
::::..:::::::::::::::::::::::::::::::::
XP_011 QHSTATRQPSMTLQRAVSLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPAD
320 330 340 350 360 370
430 440 450 460 470 480
pF1KB4 LSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLR
:::::.:::.::::::..::.:.::::::::: :::.:::.:::.::.:.:::.::::::
XP_011 LSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLR
380 390 400 410 420 430
490 500 510 520 530 540
pF1KB4 EQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDD
::::: :::::::::::..::::::::.::::...:: ::::::::.:::::::::::::
XP_011 EQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDD
440 450 460 470 480 490
550 560 570 580 590 600
pF1KB4 EWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPGLSDDYY
:::::: : .:.::..::::::.:::.:::::::::::.:. :.:.:. :.:::.:: :
XP_011 EWWQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGY
500 510 520 530 540 550
610 620 630 640 650 660
pF1KB4 GAKNLKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTR
:.:.:.:::: ::::::::::::.:.::::::::::::.::::::::: :::::::::::
XP_011 GTKTLRGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTR
560 570 580 590 600 610
670 680 690 700 710 720
pF1KB4 PRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCIL
:.:: ::::.:::::.::::::::::..:::::::.::::::::.:::: ::::::::::
XP_011 PKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCIL
620 630 640 650 660 670
730 740 750 760 770 780
pF1KB4 DVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYF
::::::::::: ::::::::::::.:.: :::::.: : :::.: ::.:.::::::::::
XP_011 DVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYF
680 690 700 710 720 730
790 800 810
pF1KB4 TAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL
:::::::.::.:::. : .::.::: .::.:: :::
XP_011 TAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL
740 750 760
>>XP_016872774 (OMIM: 603583) PREDICTED: disks large hom (796 aa)
initn: 3576 init1: 2420 opt: 2420 Z-score: 1473.3 bits: 283.5 E(85289): 2.5e-75
Smith-Waterman score: 3557; 73.3% identity (88.0% similar) in 726 aa overlap (115-817:78-796)
90 100 110 120 130 140
pF1KB4 VPPKPVPGKSTPKLNGSGPSWWPECTCTNRDWYEQVNGSDGMFKYEEIVLERGNSGLGFS
: :::.. ...:::.:::::::::::
XP_016 IENVHGYVLQSHISPLKASPAPIIVNTDTLDTIPYVNGTEIEYEFEEITLERGNSGLGFS
50 60 70 80 90 100
150 160 170 180 190 200
pF1KB4 IAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALK
:::: ::::. ::::::::::::::::: :::: ::::.::::::::::: ::.::::::
XP_016 IAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALK
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB4 EAGPVVRLVVRRRQPPPETIMEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGG
::: .::: ::::.: ::..:..:.:::::::::::::.::::::::::::.::::.::
XP_016 EAGSIVRLYVRRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGG
170 180 190 200 210 220
270 280 290 300 310 320
pF1KB4 AAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKVAKPGSLHLNDMYAPP
:::::::::.::::: ::: .:..: :::::: :::::..:::::.:: .....: :.::
XP_016 AAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSEVVYLKVGKPTTIYMTDPYGPP
230 240 250 260 270 280
330 340 350 360 370 380
pF1KB4 DYASTFTALADNHISHNSSLGYLGAVESKVSYPAPPQVPPTRYSPIPRHMLAEEDFTR--
: . ... .::. : :..: :.: : : . : ::::::.:::...:.:
XP_016 DITHSYSPPMENHLLS----GNNGTLEYKTSLP--P-ISPGRYSPIPKHMLVDDDYTSHS
290 300 310 320 330 340
390 400 410 420
pF1KB4 ---------------------EPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPAD
::::..:::::::::::::::::::::::::::::::::
XP_016 QHSTATRQPSMTLQRAVSLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPAD
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB4 LSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLR
:::::.:::.::::::..::.:.::::::::: :::.:::.:::.::.:.:::.::::::
XP_016 LSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLR
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB4 EQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDD
::::: :::::::::::..::::::::.::::...:: ::::::::.:::::::::::::
XP_016 EQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDD
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB4 EWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPGLSDDYY
:::::: : .:.::..::::::.:::.:::::::::::.:. :.:.:. :.:::.:: :
XP_016 EWWQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGY
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB4 GAKNLKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTR
:.:.:.:::: ::::::::::::.:.::::::::::::.::::::::: :::::::::::
XP_016 GTKTLRGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTR
590 600 610 620 630 640
670 680 690 700 710 720
pF1KB4 PRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCIL
:.:: ::::.:::::.::::::::::..:::::::.::::::::.:::: ::::::::::
XP_016 PKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCIL
650 660 670 680 690 700
730 740 750 760 770 780
pF1KB4 DVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYF
::::::::::: ::::::::::::.:.: :::::.: : :::.: ::.:.::::::::::
XP_016 DVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYF
710 720 730 740 750 760
790 800 810
pF1KB4 TAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL
:::::::.::.:::. : .::.::: .::.:: :::
XP_016 TAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL
770 780 790
>>XP_016872772 (OMIM: 603583) PREDICTED: disks large hom (810 aa)
initn: 3499 init1: 2420 opt: 2420 Z-score: 1473.2 bits: 283.5 E(85289): 2.6e-75
Smith-Waterman score: 3461; 68.5% identity (82.3% similar) in 778 aa overlap (115-817:40-810)
90 100 110 120 130 140
pF1KB4 VPPKPVPGKSTPKLNGSGPSWWPECTCTNRDWYEQVNGSDGMFKYEEIVLERGNSGLGFS
: :::.. ...:::.:::::::::::
XP_016 KLGRRFVHNARKAKSEKASPAPIIVNTDTLDTIPYVNGTEIEYEFEEITLERGNSGLGFS
10 20 30 40 50 60
150 160 170 180 190 200
pF1KB4 IAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALK
:::: ::::. ::::::::::::::::: :::: ::::.::::::::::: ::.::::::
XP_016 IAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALK
70 80 90 100 110 120
210 220 230 240 250 260
pF1KB4 EAGPVVRLVVRRRQPPPETIMEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGG
::: .::: ::::.: ::..:..:.:::::::::::::.::::::::::::.::::.::
XP_016 EAGSIVRLYVRRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGG
130 140 150 160 170 180
270 280 290 300 310 320
pF1KB4 AAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKVAKPGSLHLNDMYAPP
:::::::::.::::: ::: .:..: :::::: :::::..:::::.:: .....: :.::
XP_016 AAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSEVVYLKVGKPTTIYMTDPYGPP
190 200 210 220 230 240
330 340 350 360 370 380
pF1KB4 DYASTFTALADNHISHNSSLGYLGAVESKVSYPAPPQVPPTRYSPIPRHMLAEEDFTR--
: . ... .::. : :..: :.: : : . : ::::::.:::...:.::
XP_016 DITHSYSPPMENHLLS----GNNGTLEYKTSLP--P-ISPGRYSPIPKHMLVDDDYTRPP
250 260 270 280 290 300
pF1KB4 ------------------------------------------------------------
XP_016 EPVYSTVNKLCDKPASPRHYSPVECDKSFLLSAPYSHYHLGLLPDSEMTSHSQHSTATRQ
310 320 330 340 350 360
390 400 410 420
pF1KB4 -------------EPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRG
::::..::::::::::::::::::::::::::::::::::::::.::
XP_016 PSMTLQRAVSLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 DRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSM
:.::::::..::.:.::::::::: :::.:::.:::.::.:.:::.::::::::::: ::
XP_016 DQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 SSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLV
:::::::::..::::::::.::::...:: ::::::::.::::::::::::::::::: :
XP_016 SSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 TPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPGLSDDYYGAKNLKGQ
.:.::..::::::.:::.:::::::::::.:. :.:.:. :.:::.:: ::.:.:.::
XP_016 MLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTKTLRGQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 EDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVD
:: ::::::::::::.:.::::::::::::.::::::::: ::::::::::::.:: :::
XP_016 EDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 GQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIK
:.:::::.::::::::::..:::::::.::::::::.:::: ::::::::::::::::::
XP_016 GRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 RLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDS
::: ::::::::::::.:.: :::::.: : :::.: ::.:.:::::::::::::::::.
XP_016 RLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDT
730 740 750 760 770 780
790 800 810
pF1KB4 LEEIYNKIKQIIEDQSGHYIWVPSPEKL
::.:::. : .::.::: .::.:: :::
XP_016 LEDIYNQCKLVIEEQSGPFIWIPSKEKL
790 800 810
>>XP_005273868 (OMIM: 603583) PREDICTED: disks large hom (819 aa)
initn: 3499 init1: 2420 opt: 2420 Z-score: 1473.1 bits: 283.5 E(85289): 2.6e-75
Smith-Waterman score: 3461; 68.5% identity (82.3% similar) in 778 aa overlap (115-817:49-819)
90 100 110 120 130 140
pF1KB4 VPPKPVPGKSTPKLNGSGPSWWPECTCTNRDWYEQVNGSDGMFKYEEIVLERGNSGLGFS
: :::.. ...:::.:::::::::::
XP_005 IASLKQCEQAMQHAFIPASPAPIIVNTDTLDTIPYVNGTEIEYEFEEITLERGNSGLGFS
20 30 40 50 60 70
150 160 170 180 190 200
pF1KB4 IAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALK
:::: ::::. ::::::::::::::::: :::: ::::.::::::::::: ::.::::::
XP_005 IAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALK
80 90 100 110 120 130
210 220 230 240 250 260
pF1KB4 EAGPVVRLVVRRRQPPPETIMEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGG
::: .::: ::::.: ::..:..:.:::::::::::::.::::::::::::.::::.::
XP_005 EAGSIVRLYVRRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGG
140 150 160 170 180 190
270 280 290 300 310 320
pF1KB4 AAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKVAKPGSLHLNDMYAPP
:::::::::.::::: ::: .:..: :::::: :::::..:::::.:: .....: :.::
XP_005 AAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSEVVYLKVGKPTTIYMTDPYGPP
200 210 220 230 240 250
330 340 350 360 370 380
pF1KB4 DYASTFTALADNHISHNSSLGYLGAVESKVSYPAPPQVPPTRYSPIPRHMLAEEDFTR--
: . ... .::. : :..: :.: : : . : ::::::.:::...:.::
XP_005 DITHSYSPPMENHLLS----GNNGTLEYKTSLP--P-ISPGRYSPIPKHMLVDDDYTRPP
260 270 280 290 300 310
pF1KB4 ------------------------------------------------------------
XP_005 EPVYSTVNKLCDKPASPRHYSPVECDKSFLLSAPYSHYHLGLLPDSEMTSHSQHSTATRQ
320 330 340 350 360 370
390 400 410 420
pF1KB4 -------------EPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRG
::::..::::::::::::::::::::::::::::::::::::::.::
XP_005 PSMTLQRAVSLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRG
380 390 400 410 420 430
430 440 450 460 470 480
pF1KB4 DRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSM
:.::::::..::.:.::::::::: :::.:::.:::.::.:.:::.::::::::::: ::
XP_005 DQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSM
440 450 460 470 480 490
490 500 510 520 530 540
pF1KB4 SSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLV
:::::::::..::::::::.::::...:: ::::::::.::::::::::::::::::: :
XP_005 SSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRV
500 510 520 530 540 550
550 560 570 580 590 600
pF1KB4 TPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPGLSDDYYGAKNLKGQ
.:.::..::::::.:::.:::::::::::.:. :.:.:. :.:::.:: ::.:.:.::
XP_005 MLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTKTLRGQ
560 570 580 590 600 610
610 620 630 640 650 660
pF1KB4 EDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVD
:: ::::::::::::.:.::::::::::::.::::::::: ::::::::::::.:: :::
XP_005 EDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVD
620 630 640 650 660 670
670 680 690 700 710 720
pF1KB4 GQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIK
:.:::::.::::::::::..:::::::.::::::::.:::: ::::::::::::::::::
XP_005 GRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIK
680 690 700 710 720 730
730 740 750 760 770 780
pF1KB4 RLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDS
::: ::::::::::::.:.: :::::.: : :::.: ::.:.:::::::::::::::::.
XP_005 RLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDT
740 750 760 770 780 790
790 800 810
pF1KB4 LEEIYNKIKQIIEDQSGHYIWVPSPEKL
::.:::. : .::.::: .::.:: :::
XP_005 LEDIYNQCKLVIEEQSGPFIWIPSKEKL
800 810
817 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 14:38:31 2016 done: Thu Nov 3 14:38:33 2016
Total Scan time: 13.310 Total Display time: 0.260
Function used was FASTA [36.3.4 Apr, 2011]