Result of FASTA (omim) for
pF1KB4126
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4126, 433 aa
1>>>pF1KB4126 433 - 433 aa - 433 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2247+/-0.000506; mu= 18.1891+/- 0.031
mean_var=94.5797+/-23.321, 0's: 0 Z-trim(108.0): 270 B-trim: 1998 in 2/51
Lambda= 0.131879
statistics sampled from 15622 (16026) to 15622 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.524), E-opt: 0.2 (0.188), width: 16
Scan time: 8.190
The best scores are: opt bits E(85289)
NP_005286 (OMIM: 601910) probable G-protein couple ( 433) 2782 540.6 3e-153
XP_011514358 (OMIM: 601910) PREDICTED: probable G- ( 433) 2782 540.6 3e-153
NP_000721 (OMIM: 118444) cholecystokinin receptor ( 428) 339 75.8 2.5e-13
NP_000854 (OMIM: 182131) 5-hydroxytryptamine recep ( 390) 265 61.6 4e-09
XP_011531954 (OMIM: 600167) PREDICTED: histamine H ( 487) 237 56.4 1.9e-07
NP_001091683 (OMIM: 600167) histamine H1 receptor ( 487) 237 56.4 1.9e-07
XP_016861773 (OMIM: 600167) PREDICTED: histamine H ( 487) 237 56.4 1.9e-07
NP_001091681 (OMIM: 600167) histamine H1 receptor ( 487) 237 56.4 1.9e-07
XP_016861772 (OMIM: 600167) PREDICTED: histamine H ( 487) 237 56.4 1.9e-07
XP_011531955 (OMIM: 600167) PREDICTED: histamine H ( 487) 237 56.4 1.9e-07
NP_000852 (OMIM: 600167) histamine H1 receptor [Ho ( 487) 237 56.4 1.9e-07
NP_001091682 (OMIM: 600167) histamine H1 receptor ( 487) 237 56.4 1.9e-07
XP_006712545 (OMIM: 601122) PREDICTED: 5-hydroxytr ( 456) 227 54.5 6.7e-07
NP_000857 (OMIM: 182134) 5-hydroxytryptamine recep ( 366) 218 52.7 1.9e-06
NP_001309139 (OMIM: 182134) 5-hydroxytryptamine re ( 366) 218 52.7 1.9e-06
NP_001309138 (OMIM: 182134) 5-hydroxytryptamine re ( 366) 218 52.7 1.9e-06
XP_011531966 (OMIM: 182134) PREDICTED: 5-hydroxytr ( 366) 218 52.7 1.9e-06
NP_001309137 (OMIM: 182134) 5-hydroxytryptamine re ( 366) 218 52.7 1.9e-06
XP_005264808 (OMIM: 182134) PREDICTED: 5-hydroxytr ( 366) 218 52.7 1.9e-06
NP_795344 (OMIM: 118445) gastrin/cholecystokinin t ( 447) 219 52.9 1.9e-06
NP_387512 (OMIM: 126451,181500,190300) D(3) dopami ( 367) 217 52.5 2.2e-06
NP_001307687 (OMIM: 601122) 5-hydroxytryptamine re ( 439) 216 52.4 2.8e-06
NP_000858 (OMIM: 601122) 5-hydroxytryptamine recep ( 481) 216 52.4 3e-06
XP_016874005 (OMIM: 118445) PREDICTED: gastrin/cho ( 381) 213 51.7 3.8e-06
NP_000675 (OMIM: 109630,607276) beta-1 adrenergic ( 477) 204 50.1 1.4e-05
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 201 49.6 2.1e-05
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 201 49.6 2.3e-05
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 194 48.2 5e-05
NP_000665 (OMIM: 102775) adenosine receptor A1 [Ho ( 326) 191 47.5 6.1e-05
NP_001041695 (OMIM: 102775) adenosine receptor A1 ( 326) 191 47.5 6.1e-05
NP_004239 (OMIM: 600895) prolactin-releasing pepti ( 370) 184 46.2 0.00017
NP_444264 (OMIM: 607449) neuropeptide FF receptor ( 420) 180 45.5 0.00031
NP_001138228 (OMIM: 607449) neuropeptide FF recept ( 423) 180 45.5 0.00031
NP_004113 (OMIM: 601898) growth hormone secretagog ( 289) 178 45.0 0.00031
NP_004876 (OMIM: 607449) neuropeptide FF receptor ( 522) 180 45.6 0.00036
NP_940799 (OMIM: 601898) growth hormone secretagog ( 366) 178 45.1 0.00037
NP_001025186 (OMIM: 606665) melanopsin isoform 2 [ ( 489) 179 45.4 0.0004
XP_016872444 (OMIM: 606665) PREDICTED: melanopsin ( 539) 179 45.4 0.00042
XP_016871876 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 174 44.3 0.00064
XP_011538239 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 174 44.3 0.00064
XP_016871875 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 174 44.3 0.00064
NP_005963 (OMIM: 601790) neuropeptide Y receptor t ( 375) 174 44.3 0.00064
XP_011538238 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 174 44.3 0.00064
NP_001265723 (OMIM: 601790) neuropeptide Y recepto ( 375) 174 44.3 0.00064
XP_005261778 (OMIM: 182453) PREDICTED: somatostati ( 418) 172 44.0 0.00089
XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 172 44.0 0.00089
XP_016884412 (OMIM: 182453) PREDICTED: somatostati ( 418) 172 44.0 0.00089
NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 172 44.0 0.00089
XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 172 44.0 0.00089
XP_011528651 (OMIM: 182453) PREDICTED: somatostati ( 418) 172 44.0 0.00089
>>NP_005286 (OMIM: 601910) probable G-protein coupled re (433 aa)
initn: 2782 init1: 2782 opt: 2782 Z-score: 2872.3 bits: 540.6 E(85289): 3e-153
Smith-Waterman score: 2782; 100.0% identity (100.0% similar) in 433 aa overlap (1-433:1-433)
10 20 30 40 50 60
pF1KB4 MCFSPILEINMQSESNITVRDDIDDINTNMYQPLSYPLSFQVSLTGFLMLEIVLGLGSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MCFSPILEINMQSESNITVRDDIDDINTNMYQPLSYPLSFQVSLTGFLMLEIVLGLGSNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 TVLVLYCMKSNLINSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLESNTALICCFHEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TVLVLYCMKSNLINSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLESNTALICCFHEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 CVSFASVSTAINVFAITLDRYDISVKPANRILTMGRAVMLMISIWIFSFFSFLIPFIEVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CVSFASVSTAINVFAITLDRYDISVKPANRILTMGRAVMLMISIWIFSFFSFLIPFIEVN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 FFSLQSGNTWENKTLLCVSTNEYYTELGMYYHLLVQIPIFFFTVVVMLITYTKILQALNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FFSLQSGNTWENKTLLCVSTNEYYTELGMYYHLLVQIPIFFFTVVVMLITYTKILQALNI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 RIGTRFSTGQKKKARKKKTISLTTQHEATDMSQSSGGRNVVFGVRTSVSVIIALRRAVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RIGTRFSTGQKKKARKKKTISLTTQHEATDMSQSSGGRNVVFGVRTSVSVIIALRRAVKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 HRERRERQKRVFRMSLLIISTFLLCWTPISVLNTTILCLGPSDLLVKLRLCFLVMAYGTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 HRERRERQKRVFRMSLLIISTFLLCWTPISVLNTTILCLGPSDLLVKLRLCFLVMAYGTT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 IFHPLLYAFTRQKFQKVLKSKMKKRVVSIVEADPLPNNAVIHNSWIDPKRNKKITFEDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IFHPLLYAFTRQKFQKVLKSKMKKRVVSIVEADPLPNNAVIHNSWIDPKRNKKITFEDSE
370 380 390 400 410 420
430
pF1KB4 IREKCLVPQVVTD
:::::::::::::
NP_005 IREKCLVPQVVTD
430
>>XP_011514358 (OMIM: 601910) PREDICTED: probable G-prot (433 aa)
initn: 2782 init1: 2782 opt: 2782 Z-score: 2872.3 bits: 540.6 E(85289): 3e-153
Smith-Waterman score: 2782; 100.0% identity (100.0% similar) in 433 aa overlap (1-433:1-433)
10 20 30 40 50 60
pF1KB4 MCFSPILEINMQSESNITVRDDIDDINTNMYQPLSYPLSFQVSLTGFLMLEIVLGLGSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MCFSPILEINMQSESNITVRDDIDDINTNMYQPLSYPLSFQVSLTGFLMLEIVLGLGSNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 TVLVLYCMKSNLINSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLESNTALICCFHEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVLVLYCMKSNLINSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLESNTALICCFHEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 CVSFASVSTAINVFAITLDRYDISVKPANRILTMGRAVMLMISIWIFSFFSFLIPFIEVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CVSFASVSTAINVFAITLDRYDISVKPANRILTMGRAVMLMISIWIFSFFSFLIPFIEVN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 FFSLQSGNTWENKTLLCVSTNEYYTELGMYYHLLVQIPIFFFTVVVMLITYTKILQALNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFSLQSGNTWENKTLLCVSTNEYYTELGMYYHLLVQIPIFFFTVVVMLITYTKILQALNI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 RIGTRFSTGQKKKARKKKTISLTTQHEATDMSQSSGGRNVVFGVRTSVSVIIALRRAVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIGTRFSTGQKKKARKKKTISLTTQHEATDMSQSSGGRNVVFGVRTSVSVIIALRRAVKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 HRERRERQKRVFRMSLLIISTFLLCWTPISVLNTTILCLGPSDLLVKLRLCFLVMAYGTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRERRERQKRVFRMSLLIISTFLLCWTPISVLNTTILCLGPSDLLVKLRLCFLVMAYGTT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 IFHPLLYAFTRQKFQKVLKSKMKKRVVSIVEADPLPNNAVIHNSWIDPKRNKKITFEDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IFHPLLYAFTRQKFQKVLKSKMKKRVVSIVEADPLPNNAVIHNSWIDPKRNKKITFEDSE
370 380 390 400 410 420
430
pF1KB4 IREKCLVPQVVTD
:::::::::::::
XP_011 IREKCLVPQVVTD
430
>>NP_000721 (OMIM: 118444) cholecystokinin receptor type (428 aa)
initn: 168 init1: 96 opt: 339 Z-score: 360.4 bits: 75.8 E(85289): 2.5e-13
Smith-Waterman score: 339; 23.9% identity (59.5% similar) in 348 aa overlap (41-375:44-378)
20 30 40 50 60 70
pF1KB4 MQSESNITVRDDIDDINTNMYQPLSYPLSFQVSLTGFLMLEIVLGLGSNLTVLVLYCMKS
:. : ....: ::: ..:.. :: ...
NP_000 ITPPCELGLENETLFCLDQPRPSKEWQPAVQILLYSLIFLLSVLG--NTLVITVL--IRN
20 30 40 50 60
80 90 100 110 120 130
pF1KB4 NLINSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLESNTALICCFHEACVSFASVSTA
. . .:.::. ..: : :...:. :.:.... ::. . .: .. . : ..:..
NP_000 KRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVC---KTTTYFMGTSVS
70 80 90 100 110 120
140 150 160 170 180
pF1KB4 INVF---AITLDRYDISVKP-ANRIL-TMGRAVMLMISIWIFSFFSFLIPF-IEVNFFSL
...: ::.:.:: :: .:. : ..:. .. . : .:: ... :. : :. .
NP_000 VSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSF-TIMTPYPIYSNLVPF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 QSGNTWENKTLLCVSTNEYYTELGMYYHLLVQIPIFFFTVVVMLITYTKILQALNIRIGT
..:. . . :. . . .: .. . .:.. .::...: : .:.. :
NP_000 TKNNNQTANMCRFLLPNDV---MQQSWHTFLLLILFLIPGIVMMVAYGLI--SLELYQGI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 RFSTGQKKKARKKKTISLTT-QHEATD---MSQSSGGRNVVFGVRTSVSVIIALRRAVKR
.: ..:::.:...: . .. ..: .: .... :.. . .. : : : .
NP_000 KFEASQKKSAKERKPSTTSSGKYEDSDGCYLQKTRPPRKLELRQLSTGSSSRANRIRSNS
250 260 270 280 290 300
310 320 330 340 350
pF1KB4 HRERRERQKRVFRMSLLIISTFLLCWTPISVLNT--TILCLGPSDLLVKLRLCF-LVMAY
.:::.:: ..:. :.::: :: :. . . : . : :...:
NP_000 SAANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTASAERRLSGTPISFILLLSY
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB4 GTTIFHPLLYAFTRQKFQKVLKSKMKKRVVSIVEADPLPNNAVIHNSWIDPKRNKKITFE
.. .:..: : ..:.
NP_000 TSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGARGEVGEEEEGGTTGASLSRFSYSH
370 380 390 400 410 420
>>NP_000854 (OMIM: 182131) 5-hydroxytryptamine receptor (390 aa)
initn: 135 init1: 61 opt: 265 Z-score: 284.8 bits: 61.6 E(85289): 4e-09
Smith-Waterman score: 265; 19.5% identity (55.3% similar) in 374 aa overlap (30-388:39-390)
10 20 30 40 50
pF1KB4 MCFSPILEINMQSESNITVRDDIDDINTNMYQPLSYPLSFQVSLTGFL-MLEIVLGLGS
.:: : : ..: :. .: .. .. :..
NP_000 APPPPAGSETWVPQANLSSAPSQNCSAKDYIYQD-SISLPWKVLLVMLLALITLATTLSN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 NLTVLVLYCMKSNLINSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLESNTALICCFH
... ..: .. ... .: . .: : :... . .:.. . . . . ..: :
NP_000 AFVIATVY--RTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFW
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB4 EACVSFASVSTAINVFAITLDRY----DISVKPANRILTMGRAVMLMISIWIFSFFSFLI
. ... ... .:.:::: : :.: : ::.... .:.::. :
NP_000 LSSDITCCTASILHLCVIALDRYWAITDAVEYSAKR--TPKRAAVMIALVWVFSISISLP
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB4 PFIEVNFFSLQSGNTWENKTLLCVSTNEYYTELGMYYHLLVQIPIFFFTVVVMLITY---
:: : :. :... :: .... . : . . :.: ..... :
NP_000 PF-----FWRQAKA--EEEVSECVVNTDH-----ILYTVYSTVGAFYFPTLLLIALYGRI
190 200 210 220 230
240 250 260 270 280
pF1KB4 -----TKILQALNIRIGTRFSTGQKKKARKKKTISLTT-QHEATDMSQSSGGRNVVFGVR
..::. : : :.. .: .: :.:. . .. :. . ::. : :.
NP_000 YVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVK
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB4 TSVSVIIALRRAVKRHRERRERQKRVFRMSLLIISTFLLCWTPISVLNTTI-LCLGPSDL
. :: . .. . ::: .. . .:...:..:: :. ... .. .: .
NP_000 VRVSDALLEKKKLMAARER-----KATKTLGIILGAFIVCWLPFFIISLVMPICKDACWF
300 310 320 330 340
350 360 370 380 390 400
pF1KB4 LVKLRLCFLVMAYGTTIFHPLLYAFTRQKFQKVLKSKMKKRVVSIVEADPLPNNAVIHNS
. . : ..: .....:..:... . :...... .. . .:
NP_000 HLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTS
350 360 370 380 390
410 420 430
pF1KB4 WIDPKRNKKITFEDSEIREKCLVPQVVTD
>>XP_011531954 (OMIM: 600167) PREDICTED: histamine H1 re (487 aa)
initn: 112 init1: 83 opt: 237 Z-score: 254.8 bits: 56.4 E(85289): 1.9e-07
Smith-Waterman score: 237; 28.8% identity (59.8% similar) in 229 aa overlap (15-238:6-217)
10 20 30 40 50
pF1KB4 MCFSPILEINMQSESNITVRDDIDDIN-TNMYQPLSYPLSFQVSLTGFLMLEIVLGLGSN
:. ..: . . : :.: .: .:: : :. . .. . : :
XP_011 MSLPNSSCLLEDKMCEGNKTTMASPQLMPLV--VVLSTICLVTV----GLN
10 20 30 40
60 70 80 90 100 110
pF1KB4 LTVLVLYCMKSNL-INSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLESNTALICCFH
: :::: ..:. ...:.:. ..: : :.:. . .:..:. ::.: : .: :
XP_011 L--LVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMNILYLLMSKWSLGRPLCLFW
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB4 EACVSFASVSTAINVFAITLDRYDISVKPANRIL---TMGRAVMLMISIWIFSFFSFLIP
. ::... ..:: . .::: ::. : : : :: ... :..::. ..::
XP_011 LSMDYVASTASIFSVFILCIDRYR-SVQQPLRYLKYRTKTRASATILGAWFLSFL-WVIP
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB4 FIEVNFFSLQSGNTWENKTLLCVSTNEYYTELGMYYHLLVQIPIFFFTVVVMLITYTKIL
.. : : :.. :.: : . ..: ...... : :.. ...:: :.::
XP_011 ILGWNHFMQQTSVRREDK---CET--DFYDV--TWFKVMTAIINFYLPTLLMLWFYAKIY
170 180 190 200 210
240 250 260 270 280 290
pF1KB4 QALNIRIGTRFSTGQKKKARKKKTISLTTQHEATDMSQSSGGRNVVFGVRTSVSVIIALR
.:.
XP_011 KAVRQHCQHRELINRSLPSFSEIKLRPENPKGDAKKPGKESPWEVLKRKPKDAGGGSVLK
220 230 240 250 260 270
>>NP_001091683 (OMIM: 600167) histamine H1 receptor [Hom (487 aa)
initn: 112 init1: 83 opt: 237 Z-score: 254.8 bits: 56.4 E(85289): 1.9e-07
Smith-Waterman score: 237; 28.8% identity (59.8% similar) in 229 aa overlap (15-238:6-217)
10 20 30 40 50
pF1KB4 MCFSPILEINMQSESNITVRDDIDDIN-TNMYQPLSYPLSFQVSLTGFLMLEIVLGLGSN
:. ..: . . : :.: .: .:: : :. . .. . : :
NP_001 MSLPNSSCLLEDKMCEGNKTTMASPQLMPLV--VVLSTICLVTV----GLN
10 20 30 40
60 70 80 90 100 110
pF1KB4 LTVLVLYCMKSNL-INSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLESNTALICCFH
: :::: ..:. ...:.:. ..: : :.:. . .:..:. ::.: : .: :
NP_001 L--LVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMNILYLLMSKWSLGRPLCLFW
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB4 EACVSFASVSTAINVFAITLDRYDISVKPANRIL---TMGRAVMLMISIWIFSFFSFLIP
. ::... ..:: . .::: ::. : : : :: ... :..::. ..::
NP_001 LSMDYVASTASIFSVFILCIDRYR-SVQQPLRYLKYRTKTRASATILGAWFLSFL-WVIP
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB4 FIEVNFFSLQSGNTWENKTLLCVSTNEYYTELGMYYHLLVQIPIFFFTVVVMLITYTKIL
.. : : :.. :.: : . ..: ...... : :.. ...:: :.::
NP_001 ILGWNHFMQQTSVRREDK---CET--DFYDV--TWFKVMTAIINFYLPTLLMLWFYAKIY
170 180 190 200 210
240 250 260 270 280 290
pF1KB4 QALNIRIGTRFSTGQKKKARKKKTISLTTQHEATDMSQSSGGRNVVFGVRTSVSVIIALR
.:.
NP_001 KAVRQHCQHRELINRSLPSFSEIKLRPENPKGDAKKPGKESPWEVLKRKPKDAGGGSVLK
220 230 240 250 260 270
>>XP_016861773 (OMIM: 600167) PREDICTED: histamine H1 re (487 aa)
initn: 112 init1: 83 opt: 237 Z-score: 254.8 bits: 56.4 E(85289): 1.9e-07
Smith-Waterman score: 237; 28.8% identity (59.8% similar) in 229 aa overlap (15-238:6-217)
10 20 30 40 50
pF1KB4 MCFSPILEINMQSESNITVRDDIDDIN-TNMYQPLSYPLSFQVSLTGFLMLEIVLGLGSN
:. ..: . . : :.: .: .:: : :. . .. . : :
XP_016 MSLPNSSCLLEDKMCEGNKTTMASPQLMPLV--VVLSTICLVTV----GLN
10 20 30 40
60 70 80 90 100 110
pF1KB4 LTVLVLYCMKSNL-INSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLESNTALICCFH
: :::: ..:. ...:.:. ..: : :.:. . .:..:. ::.: : .: :
XP_016 L--LVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMNILYLLMSKWSLGRPLCLFW
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB4 EACVSFASVSTAINVFAITLDRYDISVKPANRIL---TMGRAVMLMISIWIFSFFSFLIP
. ::... ..:: . .::: ::. : : : :: ... :..::. ..::
XP_016 LSMDYVASTASIFSVFILCIDRYR-SVQQPLRYLKYRTKTRASATILGAWFLSFL-WVIP
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB4 FIEVNFFSLQSGNTWENKTLLCVSTNEYYTELGMYYHLLVQIPIFFFTVVVMLITYTKIL
.. : : :.. :.: : . ..: ...... : :.. ...:: :.::
XP_016 ILGWNHFMQQTSVRREDK---CET--DFYDV--TWFKVMTAIINFYLPTLLMLWFYAKIY
170 180 190 200 210
240 250 260 270 280 290
pF1KB4 QALNIRIGTRFSTGQKKKARKKKTISLTTQHEATDMSQSSGGRNVVFGVRTSVSVIIALR
.:.
XP_016 KAVRQHCQHRELINRSLPSFSEIKLRPENPKGDAKKPGKESPWEVLKRKPKDAGGGSVLK
220 230 240 250 260 270
>>NP_001091681 (OMIM: 600167) histamine H1 receptor [Hom (487 aa)
initn: 112 init1: 83 opt: 237 Z-score: 254.8 bits: 56.4 E(85289): 1.9e-07
Smith-Waterman score: 237; 28.8% identity (59.8% similar) in 229 aa overlap (15-238:6-217)
10 20 30 40 50
pF1KB4 MCFSPILEINMQSESNITVRDDIDDIN-TNMYQPLSYPLSFQVSLTGFLMLEIVLGLGSN
:. ..: . . : :.: .: .:: : :. . .. . : :
NP_001 MSLPNSSCLLEDKMCEGNKTTMASPQLMPLV--VVLSTICLVTV----GLN
10 20 30 40
60 70 80 90 100 110
pF1KB4 LTVLVLYCMKSNL-INSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLESNTALICCFH
: :::: ..:. ...:.:. ..: : :.:. . .:..:. ::.: : .: :
NP_001 L--LVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMNILYLLMSKWSLGRPLCLFW
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB4 EACVSFASVSTAINVFAITLDRYDISVKPANRIL---TMGRAVMLMISIWIFSFFSFLIP
. ::... ..:: . .::: ::. : : : :: ... :..::. ..::
NP_001 LSMDYVASTASIFSVFILCIDRYR-SVQQPLRYLKYRTKTRASATILGAWFLSFL-WVIP
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB4 FIEVNFFSLQSGNTWENKTLLCVSTNEYYTELGMYYHLLVQIPIFFFTVVVMLITYTKIL
.. : : :.. :.: : . ..: ...... : :.. ...:: :.::
NP_001 ILGWNHFMQQTSVRREDK---CET--DFYDV--TWFKVMTAIINFYLPTLLMLWFYAKIY
170 180 190 200 210
240 250 260 270 280 290
pF1KB4 QALNIRIGTRFSTGQKKKARKKKTISLTTQHEATDMSQSSGGRNVVFGVRTSVSVIIALR
.:.
NP_001 KAVRQHCQHRELINRSLPSFSEIKLRPENPKGDAKKPGKESPWEVLKRKPKDAGGGSVLK
220 230 240 250 260 270
>>XP_016861772 (OMIM: 600167) PREDICTED: histamine H1 re (487 aa)
initn: 112 init1: 83 opt: 237 Z-score: 254.8 bits: 56.4 E(85289): 1.9e-07
Smith-Waterman score: 237; 28.8% identity (59.8% similar) in 229 aa overlap (15-238:6-217)
10 20 30 40 50
pF1KB4 MCFSPILEINMQSESNITVRDDIDDIN-TNMYQPLSYPLSFQVSLTGFLMLEIVLGLGSN
:. ..: . . : :.: .: .:: : :. . .. . : :
XP_016 MSLPNSSCLLEDKMCEGNKTTMASPQLMPLV--VVLSTICLVTV----GLN
10 20 30 40
60 70 80 90 100 110
pF1KB4 LTVLVLYCMKSNL-INSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLESNTALICCFH
: :::: ..:. ...:.:. ..: : :.:. . .:..:. ::.: : .: :
XP_016 L--LVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMNILYLLMSKWSLGRPLCLFW
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB4 EACVSFASVSTAINVFAITLDRYDISVKPANRIL---TMGRAVMLMISIWIFSFFSFLIP
. ::... ..:: . .::: ::. : : : :: ... :..::. ..::
XP_016 LSMDYVASTASIFSVFILCIDRYR-SVQQPLRYLKYRTKTRASATILGAWFLSFL-WVIP
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB4 FIEVNFFSLQSGNTWENKTLLCVSTNEYYTELGMYYHLLVQIPIFFFTVVVMLITYTKIL
.. : : :.. :.: : . ..: ...... : :.. ...:: :.::
XP_016 ILGWNHFMQQTSVRREDK---CET--DFYDV--TWFKVMTAIINFYLPTLLMLWFYAKIY
170 180 190 200 210
240 250 260 270 280 290
pF1KB4 QALNIRIGTRFSTGQKKKARKKKTISLTTQHEATDMSQSSGGRNVVFGVRTSVSVIIALR
.:.
XP_016 KAVRQHCQHRELINRSLPSFSEIKLRPENPKGDAKKPGKESPWEVLKRKPKDAGGGSVLK
220 230 240 250 260 270
>>XP_011531955 (OMIM: 600167) PREDICTED: histamine H1 re (487 aa)
initn: 112 init1: 83 opt: 237 Z-score: 254.8 bits: 56.4 E(85289): 1.9e-07
Smith-Waterman score: 237; 28.8% identity (59.8% similar) in 229 aa overlap (15-238:6-217)
10 20 30 40 50
pF1KB4 MCFSPILEINMQSESNITVRDDIDDIN-TNMYQPLSYPLSFQVSLTGFLMLEIVLGLGSN
:. ..: . . : :.: .: .:: : :. . .. . : :
XP_011 MSLPNSSCLLEDKMCEGNKTTMASPQLMPLV--VVLSTICLVTV----GLN
10 20 30 40
60 70 80 90 100 110
pF1KB4 LTVLVLYCMKSNL-INSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLESNTALICCFH
: :::: ..:. ...:.:. ..: : :.:. . .:..:. ::.: : .: :
XP_011 L--LVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMNILYLLMSKWSLGRPLCLFW
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB4 EACVSFASVSTAINVFAITLDRYDISVKPANRIL---TMGRAVMLMISIWIFSFFSFLIP
. ::... ..:: . .::: ::. : : : :: ... :..::. ..::
XP_011 LSMDYVASTASIFSVFILCIDRYR-SVQQPLRYLKYRTKTRASATILGAWFLSFL-WVIP
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB4 FIEVNFFSLQSGNTWENKTLLCVSTNEYYTELGMYYHLLVQIPIFFFTVVVMLITYTKIL
.. : : :.. :.: : . ..: ...... : :.. ...:: :.::
XP_011 ILGWNHFMQQTSVRREDK---CET--DFYDV--TWFKVMTAIINFYLPTLLMLWFYAKIY
170 180 190 200 210
240 250 260 270 280 290
pF1KB4 QALNIRIGTRFSTGQKKKARKKKTISLTTQHEATDMSQSSGGRNVVFGVRTSVSVIIALR
.:.
XP_011 KAVRQHCQHRELINRSLPSFSEIKLRPENPKGDAKKPGKESPWEVLKRKPKDAGGGSVLK
220 230 240 250 260 270
433 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 14:27:58 2016 done: Thu Nov 3 14:27:59 2016
Total Scan time: 8.190 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]