Result of FASTA (omim) for
pF1KB4124
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4124, 993 aa
1>>>pF1KB4124 993 - 993 aa - 993 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 16.4309+/-0.000689; mu= -34.3155+/- 0.042
mean_var=1043.7412+/-228.126, 0's: 0 Z-trim(114.3): 1094 B-trim: 0 in 0/59
Lambda= 0.039699
statistics sampled from 22937 (24099) to 22937 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.613), E-opt: 0.2 (0.283), width: 16
Scan time: 12.920
The best scores are: opt bits E(85289)
NP_001275558 (OMIM: 602190) ephrin type-A receptor ( 993) 6732 403.6 2.7e-111
NP_004431 (OMIM: 602190) ephrin type-A receptor 7 ( 998) 6712 402.5 5.9e-111
XP_016865854 (OMIM: 602190) PREDICTED: ephrin type ( 989) 6672 400.2 2.9e-110
XP_005248726 (OMIM: 602190) PREDICTED: ephrin type ( 994) 6652 399.0 6.4e-110
NP_001268695 (OMIM: 600004) ephrin type-A receptor (1016) 4454 273.1 5.1e-72
NP_872272 (OMIM: 600004) ephrin type-A receptor 5 (1015) 4453 273.1 5.3e-72
NP_001291465 (OMIM: 602188) ephrin type-A receptor ( 986) 4392 269.6 5.9e-71
NP_004429 (OMIM: 602188) ephrin type-A receptor 4 ( 986) 4392 269.6 5.9e-71
NP_005224 (OMIM: 179611) ephrin type-A receptor 3 ( 983) 4315 265.2 1.2e-69
NP_001291466 (OMIM: 602188) ephrin type-A receptor ( 935) 4309 264.8 1.5e-69
XP_005264772 (OMIM: 179611) PREDICTED: ephrin type ( 982) 4309 264.8 1.6e-69
XP_005246431 (OMIM: 602188) PREDICTED: ephrin type ( 949) 4261 262.1 1e-68
XP_005264773 (OMIM: 179611) PREDICTED: ephrin type ( 918) 4153 255.9 7.4e-67
XP_005248728 (OMIM: 602190) PREDICTED: ephrin type ( 610) 4019 248.0 1.2e-64
NP_004433 (OMIM: 600997,603688) ephrin type-B rece ( 987) 3966 245.2 1.3e-63
XP_006710504 (OMIM: 600997,603688) PREDICTED: ephr ( 980) 3959 244.8 1.7e-63
NP_059145 (OMIM: 600997,603688) ephrin type-B rece ( 986) 3958 244.7 1.8e-63
NP_001296122 (OMIM: 600997,603688) ephrin type-B r (1055) 3957 244.7 1.9e-63
NP_004432 (OMIM: 600600) ephrin type-B receptor 1 ( 984) 3861 239.2 8.4e-62
NP_004434 (OMIM: 601839) ephrin type-B receptor 3 ( 998) 3655 227.4 3e-58
NP_004435 (OMIM: 600011) ephrin type-B receptor 4 ( 987) 3217 202.3 1.1e-50
XP_016865855 (OMIM: 602190) PREDICTED: ephrin type ( 442) 3059 192.8 3.4e-48
NP_065387 (OMIM: 176945) ephrin type-A receptor 8 (1005) 2690 172.1 1.3e-41
NP_005223 (OMIM: 179610) ephrin type-A receptor 1 ( 976) 2599 166.9 4.8e-40
XP_016863369 (OMIM: 600004) PREDICTED: ephrin type ( 852) 2535 163.1 5.6e-39
XP_011539271 (OMIM: 176945) PREDICTED: ephrin type ( 930) 2536 163.3 5.7e-39
XP_011539275 (OMIM: 176945) PREDICTED: ephrin type ( 930) 2536 163.3 5.7e-39
XP_011539274 (OMIM: 176945) PREDICTED: ephrin type ( 930) 2536 163.3 5.7e-39
XP_011539272 (OMIM: 176945) PREDICTED: ephrin type ( 930) 2536 163.3 5.7e-39
XP_016863367 (OMIM: 600004) PREDICTED: ephrin type ( 904) 2531 163.0 6.8e-39
XP_016863370 (OMIM: 600004) PREDICTED: ephrin type ( 817) 2411 156.0 7.4e-37
XP_016863368 (OMIM: 600004) PREDICTED: ephrin type ( 869) 2407 155.8 9.1e-37
XP_016861357 (OMIM: 600600) PREDICTED: ephrin type (1016) 2303 150.0 6.2e-35
XP_016861356 (OMIM: 600600) PREDICTED: ephrin type (1032) 2303 150.0 6.3e-35
XP_016861355 (OMIM: 600600) PREDICTED: ephrin type (1038) 2303 150.0 6.3e-35
NP_872585 (OMIM: 179611) ephrin type-A receptor 3 ( 539) 2250 146.6 3.4e-34
XP_016861699 (OMIM: 600066) PREDICTED: ephrin type (1104) 2236 146.2 9.4e-34
XP_006710505 (OMIM: 600997,603688) PREDICTED: ephr ( 956) 2153 141.3 2.3e-32
XP_005265710 (OMIM: 600004) PREDICTED: ephrin type ( 874) 2127 139.8 6.1e-32
XP_011530037 (OMIM: 600004) PREDICTED: ephrin type ( 926) 2127 139.8 6.4e-32
NP_001305690 (OMIM: 600004) ephrin type-A receptor ( 969) 2127 139.8 6.5e-32
NP_004430 (OMIM: 600004) ephrin type-A receptor 5 (1037) 2127 139.9 6.8e-32
NP_001268694 (OMIM: 600004) ephrin type-A receptor (1038) 2127 139.9 6.8e-32
XP_016867305 (OMIM: 600011) PREDICTED: ephrin type (1005) 2076 136.9 5.1e-31
NP_001296121 (OMIM: 600997,603688) ephrin type-B r ( 928) 2053 135.6 1.2e-30
NP_001268696 (OMIM: 600004) ephrin type-A receptor (1004) 2004 132.8 8.8e-30
NP_001092909 (OMIM: 611123) ephrin type-A receptor (1008) 1987 131.8 1.7e-29
XP_011510844 (OMIM: 600600) PREDICTED: ephrin type ( 394) 1955 129.5 3.4e-29
XP_016856569 (OMIM: 611123) PREDICTED: ephrin type ( 617) 1959 130.0 3.8e-29
NP_001275559 (OMIM: 602190) ephrin type-A receptor ( 279) 1895 125.9 2.9e-28
>>NP_001275558 (OMIM: 602190) ephrin type-A receptor 7 i (993 aa)
initn: 6732 init1: 6732 opt: 6732 Z-score: 2119.1 bits: 403.6 E(85289): 2.7e-111
Smith-Waterman score: 6732; 100.0% identity (100.0% similar) in 993 aa overlap (1-993:1-993)
10 20 30 40 50 60
pF1KB4 MVFQTRYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVFQTRYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 LDENYTPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDENYTPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 ETFNLYYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETFNLYYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 GFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EAENAPRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAENAPRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 FSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 NDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 VSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 YEKDQRERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEKDQRERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 TAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFKFPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFKFPGT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 KTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 TLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 HDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIED
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 DPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB4 IKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB4 TCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMS
910 920 930 940 950 960
970 980 990
pF1KB4 LGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV
:::::::::::::::::::::::::::::::::
NP_001 LGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV
970 980 990
>>NP_004431 (OMIM: 602190) ephrin type-A receptor 7 isof (998 aa)
initn: 3688 init1: 3688 opt: 6712 Z-score: 2112.9 bits: 402.5 E(85289): 5.9e-111
Smith-Waterman score: 6712; 99.5% identity (99.5% similar) in 998 aa overlap (1-993:1-998)
10 20 30 40 50 60
pF1KB4 MVFQTRYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MVFQTRYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 LDENYTPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LDENYTPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 ETFNLYYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ETFNLYYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 GFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EAENAPRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EAENAPRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 FSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 NDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 VSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKY
430 440 450 460 470 480
490 500 510 520 530
pF1KB4 YEKDQRERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEAT-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YEKDQRERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATG
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB4 ----ATAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KMFEATAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHF
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB4 KFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDV
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB4 AVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALD
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB4 AFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLS
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB4 RVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDM
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB4 SNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSL
850 860 870 880 890 900
900 910 920 930 940 950
pF1KB4 KTPLGTCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KTPLGTCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTI
910 920 930 940 950 960
960 970 980 990
pF1KB4 EDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV
::::::::::::::::::::::::::::::::::::::
NP_004 EDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV
970 980 990
>>XP_016865854 (OMIM: 602190) PREDICTED: ephrin type-A r (989 aa)
initn: 6678 init1: 4039 opt: 6672 Z-score: 2100.6 bits: 400.2 E(85289): 2.9e-110
Smith-Waterman score: 6672; 99.5% identity (99.5% similar) in 993 aa overlap (1-993:1-989)
10 20 30 40 50 60
pF1KB4 MVFQTRYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVFQTRYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 LDENYTPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDENYTPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 ETFNLYYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETFNLYYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 GFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EAENAPRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAENAPRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 FSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 NDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 VSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 YEKDQRERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEKDQRERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 TAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFKFPGT
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_016 TAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHC----T
550 560 570 580 590
610 620 630 640 650 660
pF1KB4 KTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIK
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB4 TLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRK
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB4 HDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIED
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB4 DPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDV
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB4 IKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLG
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB4 TCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMS
900 910 920 930 940 950
970 980 990
pF1KB4 LGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV
:::::::::::::::::::::::::::::::::
XP_016 LGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV
960 970 980
>>XP_005248726 (OMIM: 602190) PREDICTED: ephrin type-A r (994 aa)
initn: 6327 init1: 3688 opt: 6652 Z-score: 2094.4 bits: 399.0 E(85289): 6.4e-110
Smith-Waterman score: 6652; 99.0% identity (99.0% similar) in 998 aa overlap (1-993:1-994)
10 20 30 40 50 60
pF1KB4 MVFQTRYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVFQTRYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 LDENYTPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDENYTPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 ETFNLYYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETFNLYYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 GFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EAENAPRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EAENAPRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 FSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 NDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 VSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKY
430 440 450 460 470 480
490 500 510 520 530
pF1KB4 YEKDQRERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEAT-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YEKDQRERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATG
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB4 ----ATAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMFEATAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHC
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB4 KFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ----TKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDV
610 620 630 640 650
660 670 680 690 700 710
pF1KB4 AVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALD
660 670 680 690 700 710
720 730 740 750 760 770
pF1KB4 AFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLS
720 730 740 750 760 770
780 790 800 810 820 830
pF1KB4 RVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDM
780 790 800 810 820 830
840 850 860 870 880 890
pF1KB4 SNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSL
840 850 860 870 880 890
900 910 920 930 940 950
pF1KB4 KTPLGTCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTPLGTCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTI
900 910 920 930 940 950
960 970 980 990
pF1KB4 EDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV
::::::::::::::::::::::::::::::::::::::
XP_005 EDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV
960 970 980 990
>>NP_001268695 (OMIM: 600004) ephrin type-A receptor 5 i (1016 aa)
initn: 4295 init1: 3045 opt: 4454 Z-score: 1413.9 bits: 273.1 E(85289): 5.1e-72
Smith-Waterman score: 4454; 65.2% identity (86.5% similar) in 985 aa overlap (6-985:37-1011)
10 20 30
pF1KB4 MVFQTRYPSWIILCYIWLLRFAHTGEAQAAKEVLL
: : : : :: : :. ..:: :
NP_001 RGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALR---TLLASPSNEVNL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB4 LDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQVCQVMEPNQNNWLRTNWISKGNA
:::.. . .: ::. : ::::::. .::::.::.:::::.::: :::::: :.:::. .:
NP_001 LDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGA
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB4 QRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIRENLYVKIDTIAADESF
.:::.:::::::::::::: :::::::::.::.:.: ..::::.:: :.:::::::::::
NP_001 SRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAADESF
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB4 TQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIF
:. :::.: ::::::::..::::::::::::::::::::::::.:::::: :....::.:
NP_001 TELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVF
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB4 PDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCICKAGYQQKGDT
:::.::.. :.:.:: :.::. . ... :.::::::::::::::::.:::::..:. :
NP_001 PDTITGADSSQLLEVSGSCVNHS--VTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNGT
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB4 CEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAP
:. : ::.:.: . .:..:: ::.. .:.:. : :: :.: :::: .:::::::::
NP_001 CQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSAP
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB4 QNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGL
.: : :.:.:.: ::: ::::.:::.::.: : ::.:. . : : ::... :.:.:.::
NP_001 RNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGL
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB4 EDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVL
... : ..:::::.:::::.:::::::::: . : ...:..::.::::: :..: : ..
NP_001 KNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKIA
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB4 QRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSASINNLKPGTVYVFQI
. :. ::::::..:::.: ::::::.:::: : .:. .:.: :. . ..:::..::::::
NP_001 KNSISLSWQEPDRPNGIILEYEIKYFEKDQ-ETSYTIIKSKETTITAEGLKPASVYVFQI
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB4 RAFTAAGYGNYSPRLDVATLEEATATAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGR
:: :::::: .: :.. : ...:.::.:. . .::: ...: .::. .:.: ...
NP_001 RARTAAGYGVFSRRFEFETTP--VSVAASSDQSQIPVIAVSVTVG-VILLAVVIGVLLSG
550 560 570 580 590
580 590 600 610 620 630
pF1KB4 RHCGYSKADQEGDEE-LYFH---FKFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIE
:.:::::: :. .:: ..:: .:.::..:::::.::::::.:::.::::..:::: ::
NP_001 RRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIE
600 610 620 630 640 650
640 650 660 670 680 690
pF1KB4 RVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVH
::::::::::::::::::::::.. ::::::::::::::::::: ::::::::::::..:
NP_001 RVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIH
660 670 680 690 700 710
700 710 720 730 740 750
pF1KB4 LEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVH
::::::..:::::: :.::::.::.::.:.::::::::::::::::.:::.::.::::::
NP_001 LEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVH
720 730 740 750 760 770
760 770 780 790 800 810
pF1KB4 RDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSA
:::::::::.::::::::::::::::.::::::.::: :::::.:::::::: .::::::
NP_001 RDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSA
780 790 800 810 820 830
820 830 840 850 860 870
pF1KB4 SDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKE
:::::::::::::.::::::::.:.:::::::.:::::::.::::::.:.::::::::::
NP_001 SDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKE
840 850 860 870 880 890
880 890 900 910 920 930
pF1KB4 RAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLDQNTPDFT-TFCSVGEWLQAI
: ::::..::..:::.::::.:::: ... : .: :: ...: . .. ::::::.::
NP_001 RNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCR-VSNLLAEHSPLGSGAYRSVGEWLEAI
900 910 920 930 940 950
940 950 960 970 980 990
pF1KB4 KMERYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTG
:: :: . : ::.:...::..:.::. ::.::::::::::.:.: :..:...
NP_001 KMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVPL
960 970 980 990 1000 1010
pF1KB4 IQV
>>NP_872272 (OMIM: 600004) ephrin type-A receptor 5 isof (1015 aa)
initn: 4342 init1: 2164 opt: 4453 Z-score: 1413.6 bits: 273.1 E(85289): 5.3e-72
Smith-Waterman score: 4453; 65.2% identity (86.5% similar) in 985 aa overlap (6-985:37-1010)
10 20 30
pF1KB4 MVFQTRYPSWIILCYIWLLRFAHTGEAQAAKEVLL
: : : : :: : :. ..:: :
NP_872 RGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALR---TLLASPSNEVNL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB4 LDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQVCQVMEPNQNNWLRTNWISKGNA
:::.. . .: ::. : ::::::. .::::.::.:::::.::: :::::: :.:::. .:
NP_872 LDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGA
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB4 QRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIRENLYVKIDTIAADESF
.:::.:::::::::::::: :::::::::.::.:.: ..::::.:: :.:::::::::::
NP_872 SRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAADESF
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB4 TQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIF
:. :::.: ::::::::..::::::::::::::::::::::::.:::::: :....::.:
NP_872 TELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVF
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB4 PDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCICKAGYQQKGDT
:::.::.. :.:.:: :.::. . ... :.::::::::::::::::.:::::..:. :
NP_872 PDTITGADSSQLLEVSGSCVNHS--VTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNGT
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB4 CEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAP
:. : ::.:.: . .:..:: ::.. .:.:. : :: :.: :::: .:::::::::
NP_872 CQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSAP
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB4 QNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGL
.: : :.:.:.: ::: ::::.:::.::.: : ::.:. . : : ::... :.:.:.::
NP_872 RNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGL
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB4 EDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVL
... : ..:::::.:::::.:::::::::: . : ...:..::.::::: :..: : ..
NP_872 KNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKIA
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB4 QRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSASINNLKPGTVYVFQI
. :. ::::::..:::.: ::::::.:::: : .:. .:.: :. . ..:::..::::::
NP_872 KNSISLSWQEPDRPNGIILEYEIKYFEKDQ-ETSYTIIKSKETTITAEGLKPASVYVFQI
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB4 RAFTAAGYGNYSPRLDVATLEEATATAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGR
:: :::::: .: :.. .: . . :.::.:. . .::: ...: .::. .:.: ...
NP_872 RARTAAGYGVFSRRFE---FETTPVFAASSDQSQIPVIAVSVTVG-VILLAVVIGVLLSG
550 560 570 580 590
580 590 600 610 620 630
pF1KB4 RHCGYSKADQEGDEE-LYFH---FKFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIE
:.:::::: :. .:: ..:: .:.::..:::::.::::::.:::.::::..:::: ::
NP_872 RRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIE
600 610 620 630 640 650
640 650 660 670 680 690
pF1KB4 RVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVH
::::::::::::::::::::::.. ::::::::::::::::::: ::::::::::::..:
NP_872 RVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIH
660 670 680 690 700 710
700 710 720 730 740 750
pF1KB4 LEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVH
::::::..:::::: :.::::.::.::.:.::::::::::::::::.:::.::.::::::
NP_872 LEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVH
720 730 740 750 760 770
760 770 780 790 800 810
pF1KB4 RDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSA
:::::::::.::::::::::::::::.::::::.::: :::::.:::::::: .::::::
NP_872 RDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSA
780 790 800 810 820 830
820 830 840 850 860 870
pF1KB4 SDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKE
:::::::::::::.::::::::.:.:::::::.:::::::.::::::.:.::::::::::
NP_872 SDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKE
840 850 860 870 880 890
880 890 900 910 920 930
pF1KB4 RAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLDQNTPDFT-TFCSVGEWLQAI
: ::::..::..:::.::::.:::: ... : .: :: ...: . .. ::::::.::
NP_872 RNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCR-VSNLLAEHSPLGSGAYRSVGEWLEAI
900 910 920 930 940 950
940 950 960 970 980 990
pF1KB4 KMERYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTG
:: :: . : ::.:...::..:.::. ::.::::::::::.:.: :..:...
NP_872 KMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVPL
960 970 980 990 1000 1010
pF1KB4 IQV
>>NP_001291465 (OMIM: 602188) ephrin type-A receptor 4 i (986 aa)
initn: 3676 init1: 2132 opt: 4392 Z-score: 1394.9 bits: 269.6 E(85289): 5.9e-71
Smith-Waterman score: 4392; 64.4% identity (86.3% similar) in 967 aa overlap (30-993:28-986)
10 20 30 40 50
pF1KB4 MVFQTRYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSP-PNGWEEIS
:.:: ::::.. : :: ::.:: .::::.:
NP_001 MAGIFYFALFSCLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVS
10 20 30 40 50
60 70 80 90 100 110
pF1KB4 GLDENYTPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTC
.::. :::::::::.::::.:::::::.::.. .:::...:.:::::::::::::.:::
NP_001 IMDEKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB4 KETFNLYYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSK
::::::::::.: : : :::: .:::::::::::::: :.:.: ::::::.:..:::::
NP_001 KETFNLYYYESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB4 KGFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAE
:::::::::::::::::::.:.:::: ..::: ::::.::.. ::::::::.::...:
NP_001 KGFYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB4 EEAENAPRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTH
: ...:.:.:.:.::::::::.:.:.::..... :. : :.::. : : :..:: :
NP_001 E--KDVPKMYCGADGEWLVPIGNCLCNAGHEERSGECQACKIGYYKALSTDATCAKCPPH
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB4 SFSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGG
:.: ::.. : :. :..:: .: . :::::::: ::: :.:.:.:.:::: : ..::
NP_001 SYSVWEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGG
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB4 RNDVTYRILCKRC-SWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAV
:.:..: ..::.: . . ..: ::::.. : :::.::. . :.. :::::.:::::. ::
NP_001 RQDISYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAV
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB4 NGVSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEI
:::: . . ..:..::.:::::... :. ..: . :: :.: ::..::::: :::.
NP_001 NGVSKYNPNPDQSVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEV
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB4 KYYEKDQRERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEA
::::::: ::.: :.: . ...:..:.: : :::..:: ::::::..: :.:.: . .
NP_001 KYYEKDQNERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTT-NTV
480 490 500 510 520 530
540 550 560 570 580 590
pF1KB4 TATAVSSEQNPVIIIAVVAVAGTIILV-FMVFGFIIGRRHCGYSKADQEGDEELYFHFKF
. ... : .... :.:.:...:: ... .:.:.::. :::: ::.::: ...
NP_001 PSRIIGDGANSTVLL--VSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLN---
540 550 560 570 580 590
600 610 620 630 640 650
pF1KB4 PGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAV
:..::.:: ::::::.::..::::.::::::::.:::.::::::::::::.::::.. :
NP_001 QGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICV
600 610 620 630 640 650
660 670 680 690 700 710
pF1KB4 AIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAF
::::::.:::.::::::: ::::::::::::..:::::::. :::::. :.::::.::::
NP_001 AIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAF
660 670 680 690 700 710
720 730 740 750 760 770
pF1KB4 LRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRV
:::.::.:::::::::::::..::.::.::.:::::::::::::::::::::::::.:::
NP_001 LRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRV
720 730 740 750 760 770
780 790 800 810 820 830
pF1KB4 IEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN
.::::::.::: :::::.:::::::: :::::::::::::::::::::::::::::::::
NP_001 LEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN
780 790 800 810 820 830
840 850 860 870 880 890
pF1KB4 QDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKT
:::::::::::::: ::::: .:::::::::::::..:::: :::..:::.::::::::
NP_001 QDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKR
840 850 860 870 880 890
900 910 920 930 940 950
pF1KB4 PLGTCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIED
::: . ::: ..:.:.. :::.:::::::.:::::::::::..::.:.... ::
NP_001 TGTESSRPNTALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQED
900 910 920 930 940 950
960 970 980 990
pF1KB4 VMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV
. .::: . ::.::.::.:.::.:: ..:: . :
NP_001 LARIGITAITHQNKILSSVQAMRTQMQQMHGRMVPV
960 970 980
>>NP_004429 (OMIM: 602188) ephrin type-A receptor 4 isof (986 aa)
initn: 3676 init1: 2132 opt: 4392 Z-score: 1394.9 bits: 269.6 E(85289): 5.9e-71
Smith-Waterman score: 4392; 64.4% identity (86.3% similar) in 967 aa overlap (30-993:28-986)
10 20 30 40 50
pF1KB4 MVFQTRYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSP-PNGWEEIS
:.:: ::::.. : :: ::.:: .::::.:
NP_004 MAGIFYFALFSCLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVS
10 20 30 40 50
60 70 80 90 100 110
pF1KB4 GLDENYTPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTC
.::. :::::::::.::::.:::::::.::.. .:::...:.:::::::::::::.:::
NP_004 IMDEKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB4 KETFNLYYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSK
::::::::::.: : : :::: .:::::::::::::: :.:.: ::::::.:..:::::
NP_004 KETFNLYYYESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB4 KGFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAE
:::::::::::::::::::.:.:::: ..::: ::::.::.. ::::::::.::...:
NP_004 KGFYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB4 EEAENAPRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTH
: ...:.:.:.:.::::::::.:.:.::..... :. : :.::. : : :..:: :
NP_004 E--KDVPKMYCGADGEWLVPIGNCLCNAGHEERSGECQACKIGYYKALSTDATCAKCPPH
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB4 SFSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGG
:.: ::.. : :. :..:: .: . :::::::: ::: :.:.:.:.:::: : ..::
NP_004 SYSVWEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGG
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB4 RNDVTYRILCKRC-SWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAV
:.:..: ..::.: . . ..: ::::.. : :::.::. . :.. :::::.:::::. ::
NP_004 RQDISYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAV
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB4 NGVSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEI
:::: . . ..:..::.:::::... :. ..: . :: :.: ::..::::: :::.
NP_004 NGVSKYNPNPDQSVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEV
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB4 KYYEKDQRERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEA
::::::: ::.: :.: . ...:..:.: : :::..:: ::::::..: :.:.: . .
NP_004 KYYEKDQNERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTT-NTV
480 490 500 510 520 530
540 550 560 570 580 590
pF1KB4 TATAVSSEQNPVIIIAVVAVAGTIILV-FMVFGFIIGRRHCGYSKADQEGDEELYFHFKF
. ... : .... :.:.:...:: ... .:.:.::. :::: ::.::: ...
NP_004 PSRIIGDGANSTVLL--VSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLN---
540 550 560 570 580 590
600 610 620 630 640 650
pF1KB4 PGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAV
:..::.:: ::::::.::..::::.::::::::.:::.::::::::::::.::::.. :
NP_004 QGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICV
600 610 620 630 640 650
660 670 680 690 700 710
pF1KB4 AIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAF
::::::.:::.::::::: ::::::::::::..:::::::. :::::. :.::::.::::
NP_004 AIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAF
660 670 680 690 700 710
720 730 740 750 760 770
pF1KB4 LRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRV
:::.::.:::::::::::::..::.::.::.:::::::::::::::::::::::::.:::
NP_004 LRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRV
720 730 740 750 760 770
780 790 800 810 820 830
pF1KB4 IEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN
.::::::.::: :::::.:::::::: :::::::::::::::::::::::::::::::::
NP_004 LEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN
780 790 800 810 820 830
840 850 860 870 880 890
pF1KB4 QDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKT
:::::::::::::: ::::: .:::::::::::::..:::: :::..:::.::::::::
NP_004 QDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKR
840 850 860 870 880 890
900 910 920 930 940 950
pF1KB4 PLGTCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIED
::: . ::: ..:.:.. :::.:::::::.:::::::::::..::.:.... ::
NP_004 TGTESSRPNTALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQED
900 910 920 930 940 950
960 970 980 990
pF1KB4 VMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV
. .::: . ::.::.::.:.::.:: ..:: . :
NP_004 LARIGITAITHQNKILSSVQAMRTQMQQMHGRMVPV
960 970 980
>>NP_005224 (OMIM: 179611) ephrin type-A receptor 3 isof (983 aa)
initn: 4275 init1: 1998 opt: 4315 Z-score: 1371.1 bits: 265.2 E(85289): 1.2e-69
Smith-Waterman score: 4315; 63.6% identity (87.4% similar) in 958 aa overlap (28-982:25-975)
10 20 30 40 50 60
pF1KB4 MVFQTRYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISG
: ..:: :::::. : :: ::: : .:::::::
NP_005 MDCQLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISG
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 LDENYTPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCK
.::.::::::::::.::. .:::::::::. ...::.:.::::::::::::.: ::::::
NP_005 VDEHYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB4 ETFNLYYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKK
:::::::.:.: : : ..::. ..::::::::::::: :::.: .:::::.::.::..::
NP_005 ETFNLYYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKK
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB4 GFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEE
::::::::::::.:::::.::.::: ..:::.::::: . .:::::::.::....:
NP_005 GFYLAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB4 EAENAPRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHS
:. :::.::.::::::::::: :.:::...: :. : ::::. . ...:..:: ::
NP_005 --EDPPRMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB4 FSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGR
....:: :.::..:.:: .::: .:::::::.:.:.: :::.:.: :.:: : :.:::
NP_005 STQEDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGR
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB4 NDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNG
.:::. :.::.:.:. .: ::. :. ..:.: :: .. ::: :::::.:::::..::::
NP_005 KDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNG
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB4 VSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKY
::.:: : ::::::::.::::: : . :.:. . :. :::::::::::.: .::.::
NP_005 VSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKY
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB4 YEKDQRERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATA
:::...: .:. .....:...:..::: :.::::::: ::::::. : ... : .. .
NP_005 YEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDSFS
480 490 500 510 520 530
550 560 570 580 590
pF1KB4 TAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYF---HFKF
.:.:.. :..::. :... :.:. ... .::: :::.. ...:.: :.:.
NP_005 --ISGESSQVVMIAISAAVAIILLTVVIY-VLIGR-FCGYKSKHGADEKRLHFGNGHLKL
540 550 560 570 580 590
600 610 620 630 640 650
pF1KB4 PGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAV
:: .::.::.:::::..:::.:::::::. :.:..:.::::::::::::::::.:....:
NP_005 PGLRTYVDPHTYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISV
600 610 620 630 640 650
660 670 680 690 700 710
pF1KB4 AIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAF
:::::::::::::::::: ::::::::::::...::::::..:::::: :.::::.::.:
NP_005 AIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSF
660 670 680 690 700 710
720 730 740 750 760 770
pF1KB4 LRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRV
:::::.:::::::::::::::.::.::.:::::::::::::::.::::::::::::::::
NP_005 LRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRV
720 730 740 750 760 770
780 790 800 810 820 830
pF1KB4 IEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN
.::::::.::: :::::.:::.:::: ::::::::::::::::.::::::::::::.:::
NP_005 LEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSN
780 790 800 810 820 830
840 850 860 870 880 890
pF1KB4 QDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKT
::::::..:::::: ::::::.:.:::::::::.: .::::::::.::::.::::.:::
NP_005 QDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKI
840 850 860 870 880 890
900 910 920 930 940 950
pF1KB4 PLGTCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIED
.. .:: . ::::.. :.::: ..:.::... . :. ::.. :.: ...:... .:
NP_005 ITSAAARPSNLLLDQSNVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDD
900 910 920 930 940 950
960 970 980 990
pF1KB4 VMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV
. ..:.:.:: ::::.:::.....:
NP_005 MKKVGVTVVGPQKKIISSIKALETQSKNGPVPV
960 970 980
>>NP_001291466 (OMIM: 602188) ephrin type-A receptor 4 i (935 aa)
initn: 3668 init1: 2132 opt: 4309 Z-score: 1369.5 bits: 264.8 E(85289): 1.5e-69
Smith-Waterman score: 4309; 64.6% identity (86.6% similar) in 941 aa overlap (55-993:3-935)
30 40 50 60 70 80
pF1KB4 GEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQVCQVMEPNQNNW
:::.: .::. :::::::::.::::.::::
NP_001 MKWEEVSIMDEKNTPIRTYQVCNVMEPSQNNW
10 20 30
90 100 110 120 130 140
pF1KB4 LRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIRENLYV
:::.::.. .:::...:.:::::::::::::.:::::::::::::.: : : :::: .:
NP_001 LRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFV
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB4 KIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKK
::::::::::::: :.:.: ::::::.:..::::::::::::::::::::::::.:.:::
NP_001 KIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKK
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB4 CWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCI
: ..::: ::::.::.. ::::::::.::...::. ..:.:.:.:.::::::::.:.
NP_001 CPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEK--DVPKMYCGADGEWLVPIGNCL
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB4 CKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSDPP
:.::..... :. : :.::. : : :..:: ::.: ::.. : :. :..:: .:
NP_001 CNAGHEERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDAA
220 230 240 250 260 270
330 340 350 360 370 380
pF1KB4 YVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRC-SWEQGECVPCG
. :::::::: ::: :.:.:.:.:::: : ..:::.:..: ..::.: . . ..: :::
NP_001 SMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCG
280 290 300 310 320 330
390 400 410 420 430 440
pF1KB4 SNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAP
:.. : :::.::. . :.. :::::.:::::. :::::: . . ..:..::.::::
NP_001 SGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQAAP
340 350 360 370 380 390
450 460 470 480 490 500
pF1KB4 SQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSASIN
:... :. ..: . :: :.: ::..::::: :::.::::::: ::.: :.: . ...:.
NP_001 SSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDIK
400 410 420 430 440 450
510 520 530 540 550 560
pF1KB4 NLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATATAVSSEQNPVIIIAVVAVAGTII
.:.: : :::..:: ::::::..: :.:.: . . . ... : .... :.:.:...
NP_001 GLNPLTSYVFHVRARTAAGYGDFSEPLEVTT-NTVPSRIIGDGANSTVLL--VSVSGSVV
460 470 480 490 500
570 580 590 600 610 620
pF1KB4 LV-FMVFGFIIGRRHCGYSKADQEGDEELYFHFKFPGTKTYIDPETYEDPNRAVHQFAKE
:: ... .:.:.::. :::: ::.::: ... :..::.:: ::::::.::..::::
NP_001 LVVILIAAFVISRRRSKYSKAKQEADEEKHLN---QGVRTYVDPFTYEDPNQAVREFAKE
510 520 530 540 550 560
630 640 650 660 670 680
pF1KB4 LDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMG
.::::::::.:::.::::::::::::.::::.. :::::::.:::.::::::: ::::::
NP_001 IDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMG
570 580 590 600 610 620
690 700 710 720 730 740
pF1KB4 QFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMR
::::::..:::::::. :::::. :.::::.:::::::.::.:::::::::::::..::.
NP_001 QFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMK
630 640 650 660 670 680
750 760 770 780 790 800
pF1KB4 YLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEA
::.::.:::::::::::::::::::::::::.:::.::::::.::: :::::.:::::::
NP_001 YLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEA
690 700 710 720 730 740
810 820 830 840 850 860
pF1KB4 IQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQ
: ::::::::::::::::::::::::::::::::::::::::::::::: ::::: .:::
NP_001 IAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQ
750 760 770 780 790 800
870 880 890 900 910 920
pF1KB4 LMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLDQNTPDFTTFCS
::::::::::..:::: :::..:::.:::::::: ::: . ::: ..:.:.. :
NP_001 LMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSSPEFSAVVS
810 820 830 840 850 860
930 940 950 960 970 980
pF1KB4 VGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGHQKKIMSSIQTMRAQ
::.:::::::.:::::::::::..::.:.... ::. .::: . ::.::.::.:.::.:
NP_001 VGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSVQAMRTQ
870 880 890 900 910 920
990
pF1KB4 MLHLHGTGIQV
: ..:: . :
NP_001 MQQMHGRMVPV
930
993 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 00:17:37 2016 done: Sat Nov 5 00:17:39 2016
Total Scan time: 12.920 Total Display time: 0.350
Function used was FASTA [36.3.4 Apr, 2011]