Result of FASTA (omim) for
pF1KB4091
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4091, 480 aa
1>>>pF1KB4091 480 - 480 aa - 480 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6421+/-0.000561; mu= 11.8702+/- 0.034
mean_var=191.9235+/-38.836, 0's: 0 Z-trim(113.5): 333 B-trim: 414 in 1/52
Lambda= 0.092578
statistics sampled from 22431 (22820) to 22431 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.622), E-opt: 0.2 (0.268), width: 16
Scan time: 8.240
The best scores are: opt bits E(85289)
NP_005702 (OMIM: 606018) EGF-like repeat and disco ( 480) 3439 472.8 9.2e-133
NP_001265571 (OMIM: 606018) EGF-like repeat and di ( 470) 2910 402.1 1.7e-111
NP_001297249 (OMIM: 602281) lactadherin isoform c ( 379) 1348 193.4 9.4e-49
NP_005919 (OMIM: 602281) lactadherin isoform a pre ( 387) 1334 191.5 3.5e-48
NP_001297248 (OMIM: 602281) lactadherin isoform d ( 343) 1228 177.3 5.9e-44
NP_001297250 (OMIM: 602281) lactadherin isoform e ( 275) 1069 156.0 1.3e-37
NP_001108086 (OMIM: 602281) lactadherin isoform b ( 335) 929 137.4 6.1e-32
XP_016856149 (OMIM: 188055,227400,600880,601367,61 (2087) 924 137.7 3e-31
NP_000121 (OMIM: 188055,227400,600880,601367,61230 (2224) 924 137.7 3.1e-31
NP_000123 (OMIM: 134500,300841,306700) coagulation (2351) 884 132.4 1.3e-29
XP_016877695 (OMIM: 602281) PREDICTED: lactadherin ( 243) 674 103.1 9e-22
NP_063916 (OMIM: 134500,300841,306700) coagulation ( 216) 625 96.5 7.8e-20
NP_001019800 (OMIM: 602069) neuropilin-1 isoform c ( 609) 539 85.6 4.2e-16
XP_011518058 (OMIM: 602069) PREDICTED: neuropilin- ( 628) 539 85.6 4.3e-16
NP_001019799 (OMIM: 602069) neuropilin-1 isoform b ( 644) 539 85.6 4.4e-16
XP_011518057 (OMIM: 602069) PREDICTED: neuropilin- ( 656) 539 85.6 4.4e-16
XP_006717589 (OMIM: 602069) PREDICTED: neuropilin- ( 663) 539 85.7 4.5e-16
XP_016872355 (OMIM: 602069) PREDICTED: neuropilin- ( 742) 539 85.7 4.8e-16
XP_006717588 (OMIM: 602069) PREDICTED: neuropilin- ( 888) 539 85.8 5.3e-16
XP_006717587 (OMIM: 602069) PREDICTED: neuropilin- ( 889) 539 85.8 5.3e-16
XP_016872354 (OMIM: 602069) PREDICTED: neuropilin- ( 899) 539 85.8 5.4e-16
NP_001316997 (OMIM: 602069) neuropilin-1 isoform f ( 906) 539 85.8 5.4e-16
XP_006717585 (OMIM: 602069) PREDICTED: neuropilin- ( 907) 539 85.8 5.4e-16
NP_001231902 (OMIM: 602069) neuropilin-1 isoform e ( 916) 539 85.8 5.4e-16
NP_001231901 (OMIM: 602069) neuropilin-1 isoform d ( 917) 539 85.8 5.4e-16
NP_003864 (OMIM: 602069) neuropilin-1 isoform a pr ( 923) 539 85.8 5.5e-16
XP_006717584 (OMIM: 602069) PREDICTED: neuropilin- ( 924) 539 85.8 5.5e-16
XP_011510721 (OMIM: 608698) PREDICTED: discoidin, ( 699) 478 77.5 1.3e-13
NP_563615 (OMIM: 608698) discoidin, CUB and LCCL d ( 775) 478 77.6 1.4e-13
NP_957716 (OMIM: 602070) neuropilin-2 isoform 6 pr ( 555) 361 61.8 5.7e-09
XP_016860677 (OMIM: 602070) PREDICTED: neuropilin- ( 848) 361 62.0 7.4e-09
XP_016860676 (OMIM: 602070) PREDICTED: neuropilin- ( 853) 361 62.0 7.5e-09
XP_016860675 (OMIM: 602070) PREDICTED: neuropilin- ( 901) 361 62.1 7.7e-09
NP_957719 (OMIM: 602070) neuropilin-2 isoform 5 pr ( 901) 361 62.1 7.7e-09
NP_061004 (OMIM: 602070) neuropilin-2 isoform 4 pr ( 906) 361 62.1 7.7e-09
NP_958436 (OMIM: 602070) neuropilin-2 isoform 3 pr ( 909) 361 62.1 7.8e-09
XP_016860674 (OMIM: 602070) PREDICTED: neuropilin- ( 926) 361 62.1 7.8e-09
NP_003863 (OMIM: 602070) neuropilin-2 isoform 2 pr ( 926) 361 62.1 7.8e-09
XP_005246991 (OMIM: 602070) PREDICTED: neuropilin- ( 931) 361 62.1 7.9e-09
XP_005246990 (OMIM: 602070) PREDICTED: neuropilin- ( 931) 361 62.1 7.9e-09
NP_957718 (OMIM: 602070) neuropilin-2 isoform 1 pr ( 931) 361 62.1 7.9e-09
XP_011513464 (OMIM: 602981) PREDICTED: adipocyte e (1132) 348 60.4 3e-08
NP_001120 (OMIM: 602981) adipocyte enhancer-bindin (1158) 348 60.5 3e-08
NP_000321 (OMIM: 300839,312700) retinoschisin prec ( 224) 333 57.5 4.4e-08
NP_001171628 (OMIM: 609555) probable carboxypeptid ( 660) 333 58.1 8.5e-08
NP_062555 (OMIM: 609555) probable carboxypeptidase ( 734) 333 58.2 9.1e-08
XP_011516860 (OMIM: 219730,609720,616220) PREDICTE (1220) 328 57.8 2e-07
XP_011516859 (OMIM: 219730,609720,616220) PREDICTE (1220) 328 57.8 2e-07
XP_011516858 (OMIM: 219730,609720,616220) PREDICTE (1276) 328 57.8 2e-07
NP_775960 (OMIM: 219730,609720,616220) protein cru (1285) 328 57.8 2e-07
>>NP_005702 (OMIM: 606018) EGF-like repeat and discoidin (480 aa)
initn: 3439 init1: 3439 opt: 3439 Z-score: 2504.5 bits: 472.8 E(85289): 9.2e-133
Smith-Waterman score: 3439; 100.0% identity (100.0% similar) in 480 aa overlap (1-480:1-480)
10 20 30 40 50 60
pF1KB4 MKRSVAVWLLVGLSLGVPQFGKGDICDPNPCENGGICLPGLADGSFSCECPDGFTDPNCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MKRSVAVWLLVGLSLGVPQFGKGDICDPNPCENGGICLPGLADGSFSCECPDGFTDPNCS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 SVVEVASDEEEPTSAGPCTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SVVEVASDEEEPTSAGPCTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 NECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 RALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 CRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 QGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 VYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCTEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCTEEE
430 440 450 460 470 480
>>NP_001265571 (OMIM: 606018) EGF-like repeat and discoi (470 aa)
initn: 2897 init1: 2897 opt: 2910 Z-score: 2122.7 bits: 402.1 E(85289): 1.7e-111
Smith-Waterman score: 3348; 97.9% identity (97.9% similar) in 480 aa overlap (1-480:1-470)
10 20 30 40 50 60
pF1KB4 MKRSVAVWLLVGLSLGVPQFGKGDICDPNPCENGGICLPGLADGSFSCECPDGFTDPNCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKRSVAVWLLVGLSLGVPQFGKGDICDPNPCENGGICLPGLADGSFSCECPDGFTDPNCS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 SVVEVASDEEEPTSAGPCTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNI
::::: :::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVVEV----------GPCTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNI
70 80 90 100 110
130 140 150 160 170 180
pF1KB4 NECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTH
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB4 RALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSP
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB4 EYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQV
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB4 CRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDK
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB4 QGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWT
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB4 VYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCTEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCTEEE
420 430 440 450 460 470
>>NP_001297249 (OMIM: 602281) lactadherin isoform c [Hom (379 aa)
initn: 1343 init1: 851 opt: 1348 Z-score: 996.3 bits: 193.4 E(85289): 9.4e-49
Smith-Waterman score: 1348; 51.1% identity (76.7% similar) in 378 aa overlap (108-476:5-379)
80 90 100 110 120 130
pF1KB4 CTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNINECEVEPCKNGGICT--
:.: : : :. . : .::.:::.:
NP_001 MWPFPEGGNTIPILHT-DICSKNPCHNGGLCEEI
10 20 30
140 150 160 170 180
pF1KB4 ------DLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTHRALFGLQKW
:. .:.: : . : .:. :: :::.:.: :.:.::.:::.. ...:::.:
NP_001 SQEVRGDVFPSYTCTCLKGYAGNHCETKCVEPLGLENGNIANSQIAASSVRVTFLGLQHW
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB4 YPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIA
: ::::. :..:::: . :: ::::.:: :.: ::::.::::.:..: ::.:..:.:
NP_001 VPELARLNRAGMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVA
100 110 120 130 140 150
250 260 270 280 290 300
pF1KB4 YSNDGKTWA-MYKVKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQVCRRHCTLR
:: .:. . .. :. ....: :: ..:. ..: : :..:::::::: :. ::::
NP_001 YSLNGHEFDFIHDVNKKHKEFV--GNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLR
160 170 180 190 200 210
310 320 330 340 350 360
pF1KB4 MELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDKQGKVNAWT
.:::::::.::..:::.:.. : : :::::: ..: .. .:.:.: :::::::. :::.
NP_001 FELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWV
220 230 240 250 260 270
370 380 390 400 410 420
pF1KB4 SGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDEKQR
.: ..::::::: .:::::::::..:: ::::.:::.:::::. .:: ::: .
NP_001 AGSYGNDQWLQVDLGSSKEVTGIITQGARNFGSVQFVASYKVAYSNDSANWTEYQDPRTG
280 290 300 310 320 330
430 440 450 460 470 480
pF1KB4 KDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCTEEE
..:.: ::.:: .:.::... :: ::..:::: .:..::.:: :::::
NP_001 SSKIFPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIALRLELLGC
340 350 360 370
>>NP_005919 (OMIM: 602281) lactadherin isoform a preprop (387 aa)
initn: 1343 init1: 851 opt: 1334 Z-score: 986.1 bits: 191.5 E(85289): 3.5e-48
Smith-Waterman score: 1339; 49.4% identity (72.6% similar) in 401 aa overlap (78-476:27-387)
50 60 70 80 90 100
pF1KB4 CECPDGFTDPNCSSVVEVASDEEEPTSAGPCTPNPCHNGGTCE-ISEAYRGDTFIGYVCK
:. ::::::: :: ::. :::.: .:.:
NP_005 MPRPRLLAALCGALLCAPSLLVALDICSKNPCHNGGLCEEISQEVRGDVFPSYTCT
10 20 30 40 50
110 120 130 140 150 160
pF1KB4 CPRGFNGIHCQHNINECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEG
: .:. : ::. :: :::.:.
NP_005 CLKGYAGNHCET--------------------------------------KCVEPLGLEN
60 70
170 180 190 200 210 220
pF1KB4 GIISNQQITASSTHRALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRV
: :.:.::.:::.. ...:::.: : ::::. :..:::: . :: ::::.:: :.: :
NP_005 GNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWIQVNLLRRMWV
80 90 100 110 120 130
230 240 250 260 270 280
pF1KB4 TGVITQGAKRIGSPEYIKSYKIAYSNDGKTWA-MYKVKGTNEDMVFRGNIDNNTPYANSF
:::.::::.:..: ::.:..:.::: .:. . .. :. ....: :: ..:. ..: :
NP_005 TGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKEFV--GNWNKNAVHVNLF
140 150 160 170 180 190
290 300 310 320 330 340
pF1KB4 TPPIKAQYVRLYPQVCRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLN
:..:::::::: :. ::::.:::::::.::..:::.:.. : : :::::: ..: .
NP_005 ETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWG
200 210 220 230 240 250
350 360 370 380 390 400
pF1KB4 MDMFTWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFV
. .:.:.: :::::::. :::..: ..::::::: .:::::::::..:: ::::
NP_005 LHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQVDLGSSKEVTGIITQGARNFGSVQFV
260 270 280 290 300 310
410 420 430 440 450 460
pF1KB4 GSYKLAYSNDGEHWTVYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYG
.:::.:::::. .:: ::: . ..:.: ::.:: .:.::... :: ::..:::: .:..
NP_005 ASYKVAYSNDSANWTEYQDPRTGSSKIFPGNWDNHSHKKNLFETPILARYVRILPVAWHN
320 330 340 350 360 370
470 480
pF1KB4 RITLRSELLGCTEEE
::.:: :::::
NP_005 RIALRLELLGC
380
>>NP_001297248 (OMIM: 602281) lactadherin isoform d prec (343 aa)
initn: 1224 init1: 851 opt: 1228 Z-score: 910.1 bits: 177.3 E(85289): 5.9e-44
Smith-Waterman score: 1228; 54.2% identity (80.7% similar) in 321 aa overlap (157-476:25-343)
130 140 150 160 170 180
pF1KB4 PCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTHRALFGL
.: :::.:.: :.:.::.:::.. ...::
NP_001 MPRPRLLAALCGALLCAPSLLVALECVEPLGLENGNIANSQIAASSVRVTFLGL
10 20 30 40 50
190 200 210 220 230 240
pF1KB4 QKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSY
:.: : ::::. :..:::: . :: ::::.:: :.: ::::.::::.:..: ::.:..
NP_001 QHWVPELARLNRAGMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAF
60 70 80 90 100 110
250 260 270 280 290 300
pF1KB4 KIAYSNDGKTWA-MYKVKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQVCRRHC
:.::: .:. . .. :. ... : :: ..:. ..: : :..:::::::: :. :
NP_001 KVAYSLNGHEFDFIHDVNKKHKE--FVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTAC
120 130 140 150 160 170
310 320 330 340 350 360
pF1KB4 TLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDKQGKVN
:::.:::::::.::..:::.:.. : : :::::: ..: .. .:.:.: :::::::. :
NP_001 TLRFELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFN
180 190 200 210 220 230
370 380 390 400 410 420
pF1KB4 AWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDE
::..: ..::::::: .:::::::::..:: ::::.:::.:::::. .:: :::
NP_001 AWVAGSYGNDQWLQVDLGSSKEVTGIITQGARNFGSVQFVASYKVAYSNDSANWTEYQDP
240 250 260 270 280 290
430 440 450 460 470 480
pF1KB4 KQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCTEEE
. ..:.: ::.:: .:.::... :: ::..:::: .:..::.:: :::::
NP_001 RTGSSKIFPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIALRLELLGC
300 310 320 330 340
>>NP_001297250 (OMIM: 602281) lactadherin isoform e [Hom (275 aa)
initn: 1074 init1: 851 opt: 1069 Z-score: 796.4 bits: 156.0 E(85289): 1.3e-37
Smith-Waterman score: 1069; 54.5% identity (80.9% similar) in 277 aa overlap (201-476:1-275)
180 190 200 210 220 230
pF1KB4 NQQITASSTHRALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVI
..:::: . :: ::::.:: :.: ::::.
NP_001 MVNAWTPSSNDDNPWIQVNLLRRMWVTGVV
10 20 30
240 250 260 270 280
pF1KB4 TQGAKRIGSPEYIKSYKIAYSNDGKTWA-MYKVKGTNEDMVFRGNIDNNTPYANSFTPPI
::::.:..: ::.:..:.::: .:. . .. :. ....: :: ..:. ..: : :.
NP_001 TQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKEFV--GNWNKNAVHVNLFETPV
40 50 60 70 80
290 300 310 320 330 340
pF1KB4 KAQYVRLYPQVCRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMF
.:::::::: :. ::::.:::::::.::..:::.:.. : : :::::: ..: .. .:
NP_001 EAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWGLHLF
90 100 110 120 130 140
350 360 370 380 390 400
pF1KB4 TWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYK
.:.: :::::::. :::..: ..::::::: .:::::::::..:: ::::.:::
NP_001 SWNPSYARLDKQGNFNAWVAGSYGNDQWLQVDLGSSKEVTGIITQGARNFGSVQFVASYK
150 160 170 180 190 200
410 420 430 440 450 460
pF1KB4 LAYSNDGEHWTVYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITL
.:::::. .:: ::: . ..:.: ::.:: .:.::... :: ::..:::: .:..::.:
NP_001 VAYSNDSANWTEYQDPRTGSSKIFPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIAL
210 220 230 240 250 260
470 480
pF1KB4 RSELLGCTEEE
: :::::
NP_001 RLELLGC
270
>>NP_001108086 (OMIM: 602281) lactadherin isoform b prec (335 aa)
initn: 933 init1: 441 opt: 929 Z-score: 694.4 bits: 137.4 E(85289): 6.1e-32
Smith-Waterman score: 1019; 41.4% identity (62.1% similar) in 401 aa overlap (78-476:27-335)
50 60 70 80 90 100
pF1KB4 CECPDGFTDPNCSSVVEVASDEEEPTSAGPCTPNPCHNGGTCE-ISEAYRGDTFIGYVCK
:. ::::::: :: ::. :::.: .:.:
NP_001 MPRPRLLAALCGALLCAPSLLVALDICSKNPCHNGGLCEEISQEVRGDVFPSYTCT
10 20 30 40 50
110 120 130 140 150 160
pF1KB4 CPRGFNGIHCQHNINECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEG
: .:. : ::. :: :::.:.
NP_001 CLKGYAGNHCET--------------------------------------KCVEPLGLEN
60 70
170 180 190 200 210 220
pF1KB4 GIISNQQITASSTHRALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRV
: :.:.::.:::.. ...:::.: : ::::. :..:::: . :: ::::.:: :.: :
NP_001 GNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWIQVNLLRRMWV
80 90 100 110 120 130
230 240 250 260 270 280
pF1KB4 TGVITQGAKRIGSPEYIKSYKIAYSNDGKTWA-MYKVKGTNEDMVFRGNIDNNTPYANSF
:::.::::.:..: ::.:..:.::: .:. . .. :. ....: :: ..:. ..: :
NP_001 TGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKEFV--GNWNKNAVHVNLF
140 150 160 170 180 190
290 300 310 320 330 340
pF1KB4 TPPIKAQYVRLYPQVCRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLN
:..:::::::: :. ::::.:::::::.::..:::.:.. : : :::::: ..: .
NP_001 ETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWG
200 210 220 230 240 250
350 360 370 380 390 400
pF1KB4 MDMFTWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFV
. .:.:.: :::::::. :::..: ..::::.
NP_001 LHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQI-------------------------
260 270 280 290
410 420 430 440 450 460
pF1KB4 GSYKLAYSNDGEHWTVYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYG
: ::.:: .:.::... :: ::..:::: .:..
NP_001 ---------------------------FPGNWDNHSHKKNLFETPILARYVRILPVAWHN
300 310 320
470 480
pF1KB4 RITLRSELLGCTEEE
::.:: :::::
NP_001 RIALRLELLGC
330
>>XP_016856149 (OMIM: 188055,227400,600880,601367,612309 (2087 aa)
initn: 934 init1: 420 opt: 924 Z-score: 682.0 bits: 137.7 E(85289): 3e-31
Smith-Waterman score: 924; 43.0% identity (68.2% similar) in 337 aa overlap (144-476:1760-2084)
120 130 140 150 160 170
pF1KB4 IHCQHNINECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQ
. : .: :.:.. :.:. ::::..:
XP_016 GSFKTLEMKASKPGWWLLNTEVGENQRAGMQTPFLIMDRDCRM----PMGLSTGIISDSQ
1730 1740 1750 1760 1770 1780
180 190 200 210 220
pF1KB4 ITASSTHRALFGLQKWYPYYARLNKKGLINAWT----AAENDRWPWIQINLQRKMRVTGV
: :: : : : : ::::. : :::. ::: ::::...:... .::.
XP_016 IKASE-----F-LGYWEPRLARLNNGGSYNAWSVEKLAAEFASKPWIQVDMQKEVIITGI
1790 1800 1810 1820 1830
230 240 250 260 270 280
pF1KB4 ITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRGNIDNNTPYANSFTPPI
:::::. . : . .:::.. .: ..: ..: . : : :: : .: :.: :::
XP_016 QTQGAKHYLKSCYTTEFYVAYSSNQINWQIFKGNSTRNVMYFNGNSDASTIKENQFDPPI
1840 1850 1860 1870 1880 1890
290 300 310 320 330 340
pF1KB4 KAQYVRLYPQVCRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMF
:.:.:. : . :::.:: :::..::: ::::..:.:.. ::::::. .. :.
XP_016 VARYIRISPTRAYNRPTLRLELQGCEVNGCSTPLGMENGKIENKQITASSFKKSWWGDY-
1900 1910 1920 1930 1940 1950
350 360 370 380 390 400
pF1KB4 TWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYK
::: .:::. ::.:::: . :...:::..::: :.:.::::: :... ..: ::
XP_016 -WEPFRARLNAQGRVNAWQAKANNNKQWLEIDLLKIKKITAIITQGCKSLSSEMYVKSYT
1960 1970 1980 1990 2000 2010
410 420 430 440 450 460
pF1KB4 LAYSNDGEHWTVYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITL
. ::..: .: :. ... ::.:.:: .. : :: ..::: .: ::..: .: :.:
XP_016 IHYSEQGVEWKPYRLKSSMVDKIFEGNTNTKGHVKNFFNPPIISRFIRVIPKTWNQSIAL
2020 2030 2040 2050 2060 2070
470 480
pF1KB4 RSELLGCTEEE
: ::.::
XP_016 RLELFGCDIY
2080
>>NP_000121 (OMIM: 188055,227400,600880,601367,612309,61 (2224 aa)
initn: 934 init1: 420 opt: 924 Z-score: 681.7 bits: 137.7 E(85289): 3.1e-31
Smith-Waterman score: 924; 43.0% identity (68.2% similar) in 337 aa overlap (144-476:1897-2221)
120 130 140 150 160 170
pF1KB4 IHCQHNINECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQ
. : .: :.:.. :.:. ::::..:
NP_000 GSFKTLEMKASKPGWWLLNTEVGENQRAGMQTPFLIMDRDCRM----PMGLSTGIISDSQ
1870 1880 1890 1900 1910 1920
180 190 200 210 220
pF1KB4 ITASSTHRALFGLQKWYPYYARLNKKGLINAWT----AAENDRWPWIQINLQRKMRVTGV
: :: : : : : ::::. : :::. ::: ::::...:... .::.
NP_000 IKASE-----F-LGYWEPRLARLNNGGSYNAWSVEKLAAEFASKPWIQVDMQKEVIITGI
1930 1940 1950 1960 1970
230 240 250 260 270 280
pF1KB4 ITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRGNIDNNTPYANSFTPPI
:::::. . : . .:::.. .: ..: ..: . : : :: : .: :.: :::
NP_000 QTQGAKHYLKSCYTTEFYVAYSSNQINWQIFKGNSTRNVMYFNGNSDASTIKENQFDPPI
1980 1990 2000 2010 2020 2030
290 300 310 320 330 340
pF1KB4 KAQYVRLYPQVCRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMF
:.:.:. : . :::.:: :::..::: ::::..:.:.. ::::::. .. :.
NP_000 VARYIRISPTRAYNRPTLRLELQGCEVNGCSTPLGMENGKIENKQITASSFKKSWWGDY-
2040 2050 2060 2070 2080 2090
350 360 370 380 390 400
pF1KB4 TWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYK
::: .:::. ::.:::: . :...:::..::: :.:.::::: :... ..: ::
NP_000 -WEPFRARLNAQGRVNAWQAKANNNKQWLEIDLLKIKKITAIITQGCKSLSSEMYVKSYT
2100 2110 2120 2130 2140 2150
410 420 430 440 450 460
pF1KB4 LAYSNDGEHWTVYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITL
. ::..: .: :. ... ::.:.:: .. : :: ..::: .: ::..: .: :.:
NP_000 IHYSEQGVEWKPYRLKSSMVDKIFEGNTNTKGHVKNFFNPPIISRFIRVIPKTWNQSIAL
2160 2170 2180 2190 2200 2210
470 480
pF1KB4 RSELLGCTEEE
: ::.::
NP_000 RLELFGCDIY
2220
>>NP_000123 (OMIM: 134500,300841,306700) coagulation fac (2351 aa)
initn: 769 init1: 399 opt: 884 Z-score: 652.6 bits: 132.4 E(85289): 1.3e-29
Smith-Waterman score: 884; 44.9% identity (67.4% similar) in 325 aa overlap (157-480:2039-2349)
130 140 150 160 170 180
pF1KB4 PCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTHRALFGL
::. :::. .: : . :::::. .:
NP_000 PSKAGIWRVECLIGEHLHAGMSTLFLVYSNKCQTPLGMASGHIRDFQITASGQ----YG-
2010 2020 2030 2040 2050 2060
190 200 210 220 230 240
pF1KB4 QKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSY
.: : :::. .: ::::.. : . ::...: : . :. ::::.. : ::...
NP_000 -QWAPKLARLHYSGSINAWSTKEP--FSWIKVDLLAPMIIHGIKTQGARQKFSSLYISQF
2070 2080 2090 2100 2110 2120
250 260 270 280 290 300
pF1KB4 KIAYSNDGKTWAMYKVKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQVCRRHCT
: :: ::: : :. ..:. ::: ::.:.. : :.::: :.:.::.: . :
NP_000 IIMYSLDGKKWQTYRGNSTGTLMVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRST
2130 2140 2150 2160 2170 2180
310 320 330 340 350 360
pF1KB4 LRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMF-TWEPRKARLDKQGKVN
:::::.::.:..:: ::::.: :.: :::::: : .:: :: : :::: ::. :
NP_000 LRMELMGCDLNSCSMPLGMESKAISDAQITASSYFT----NMFATWSPSKARLHLQGRSN
2190 2200 2210 2220 2230
370 380 390 400 410 420
pF1KB4 AWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDE
:: :. ..:::::. ::::. :::.:.. ..: . .. :.::..::..
NP_000 AWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLF--F
2240 2250 2260 2270 2280 2290
430 440 450 460 470 480
pF1KB4 KQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCTEEE
.. : :::::: :. : : .:::. .:..:: : :: .:.:: :.::: ..
NP_000 QNGKVKVFQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQDLY
2300 2310 2320 2330 2340 2350
480 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 05:36:49 2016 done: Sat Nov 5 05:36:50 2016
Total Scan time: 8.240 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]