Result of FASTA (omim) for
pF1KB3990
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3990, 1058 aa
1>>>pF1KB3990 1058 - 1058 aa - 1058 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9677+/-0.000379; mu= 15.2420+/- 0.024
mean_var=149.1784+/-28.968, 0's: 0 Z-trim(117.9): 379 B-trim: 418 in 3/53
Lambda= 0.105008
statistics sampled from 29958 (30408) to 29958 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.357), width: 16
Scan time: 10.980
The best scores are: opt bits E(85289)
NP_001291738 (OMIM: 604589) bromodomain-containing (1058) 7216 1105.9 0
XP_016884209 (OMIM: 604589) PREDICTED: bromodomain ( 955) 5386 828.7 0
XP_016884208 (OMIM: 604589) PREDICTED: bromodomain ( 958) 5386 828.7 0
XP_016884207 (OMIM: 604589) PREDICTED: bromodomain (1023) 5386 828.7 0
XP_016884204 (OMIM: 604589) PREDICTED: bromodomain (1189) 5386 828.7 0
XP_016884205 (OMIM: 604589) PREDICTED: bromodomain (1189) 5386 828.7 0
XP_016884206 (OMIM: 604589) PREDICTED: bromodomain (1189) 5386 828.7 0
NP_001291737 (OMIM: 604589) bromodomain-containing (1189) 5386 828.7 0
XP_016884210 (OMIM: 604589) PREDICTED: bromodomain ( 941) 5383 828.2 0
XP_016884203 (OMIM: 604589) PREDICTED: bromodomain (1187) 5361 825.0 0
XP_016884212 (OMIM: 604589) PREDICTED: bromodomain ( 643) 4001 618.7 3.3e-176
NP_001305978 (OMIM: 602410) peregrin isoform 3 [Ho (1119) 3747 580.4 1.9e-164
XP_005265509 (OMIM: 602410) PREDICTED: peregrin is (1125) 3305 513.5 2.7e-144
NP_001305979 (OMIM: 602410) peregrin isoform 4 [Ho (1213) 3187 495.6 7e-139
XP_005265506 (OMIM: 602410) PREDICTED: peregrin is (1247) 3187 495.6 7.1e-139
NP_004625 (OMIM: 602410) peregrin isoform 2 [Homo (1214) 3027 471.4 1.4e-131
XP_011532404 (OMIM: 602410) PREDICTED: peregrin is (1248) 3027 471.4 1.4e-131
XP_011532403 (OMIM: 602410) PREDICTED: peregrin is (1248) 3027 471.4 1.4e-131
NP_001003694 (OMIM: 602410) peregrin isoform 1 [Ho (1220) 2615 409.0 8.5e-113
XP_005265507 (OMIM: 602410) PREDICTED: peregrin is (1219) 2610 408.2 1.4e-112
XP_011528375 (OMIM: 604589) PREDICTED: bromodomain ( 784) 2171 341.5 1.1e-92
XP_016884211 (OMIM: 604589) PREDICTED: bromodomain ( 802) 2171 341.5 1.1e-92
XP_011512794 (OMIM: 616856) PREDICTED: bromodomain ( 832) 1846 292.3 7.6e-78
XP_016866231 (OMIM: 616856) PREDICTED: bromodomain (1088) 1846 292.4 9.2e-78
XP_011512793 (OMIM: 616856) PREDICTED: bromodomain (1131) 1846 292.4 9.5e-78
XP_011512792 (OMIM: 616856) PREDICTED: bromodomain (1144) 1846 292.4 9.5e-78
XP_005249067 (OMIM: 616856) PREDICTED: bromodomain (1205) 1846 292.5 9.9e-78
XP_011512791 (OMIM: 616856) PREDICTED: bromodomain (1205) 1846 292.5 9.9e-78
XP_005249068 (OMIM: 616856) PREDICTED: bromodomain (1205) 1846 292.5 9.9e-78
NP_056510 (OMIM: 616856) bromodomain and PHD finge (1205) 1846 292.5 9.9e-78
NP_001274366 (OMIM: 610514) protein Jade-1 isoform ( 830) 701 118.9 1.2e-25
NP_056103 (OMIM: 610515) protein Jade-2 isoform 3 ( 790) 700 118.7 1.3e-25
NP_001276913 (OMIM: 610515) protein Jade-2 isoform ( 791) 700 118.7 1.3e-25
XP_016864771 (OMIM: 610515) PREDICTED: protein Jad ( 833) 700 118.7 1.4e-25
XP_005272005 (OMIM: 610515) PREDICTED: protein Jad ( 834) 700 118.7 1.4e-25
XP_005272002 (OMIM: 610515) PREDICTED: protein Jad ( 834) 700 118.7 1.4e-25
XP_011541593 (OMIM: 610515) PREDICTED: protein Jad ( 834) 700 118.7 1.4e-25
XP_005272003 (OMIM: 610515) PREDICTED: protein Jad ( 834) 700 118.7 1.4e-25
NP_001295072 (OMIM: 610515) protein Jade-2 isoform ( 834) 700 118.7 1.4e-25
NP_001276914 (OMIM: 610515) protein Jade-2 isoform ( 850) 700 118.7 1.4e-25
NP_055550 (OMIM: 300618) protein Jade-3 [Homo sapi ( 823) 688 116.9 4.8e-25
NP_001070913 (OMIM: 300618) protein Jade-3 [Homo s ( 823) 688 116.9 4.8e-25
NP_001274370 (OMIM: 610514) protein Jade-1 isoform ( 509) 683 115.9 5.8e-25
NP_079176 (OMIM: 610514) protein Jade-1 isoform 2 ( 509) 683 115.9 5.8e-25
XP_016864115 (OMIM: 610514) PREDICTED: protein Jad ( 529) 683 116.0 5.9e-25
XP_016864116 (OMIM: 610514) PREDICTED: protein Jad ( 529) 683 116.0 5.9e-25
XP_005263289 (OMIM: 610514) PREDICTED: protein Jad ( 842) 683 116.1 8.3e-25
NP_001274372 (OMIM: 610514) protein Jade-1 isoform ( 842) 683 116.1 8.3e-25
NP_955352 (OMIM: 610514) protein Jade-1 isoform 1 ( 842) 683 116.1 8.3e-25
NP_001274369 (OMIM: 610514) protein Jade-1 isoform ( 842) 683 116.1 8.3e-25
>>NP_001291738 (OMIM: 604589) bromodomain-containing pro (1058 aa)
initn: 7216 init1: 7216 opt: 7216 Z-score: 5913.9 bits: 1105.9 E(85289): 0
Smith-Waterman score: 7216; 100.0% identity (100.0% similar) in 1058 aa overlap (1-1058:1-1058)
10 20 30 40 50 60
pF1KB3 MRRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASALPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASALPEP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 KVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKESSVKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKESSVKTV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 RSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LLKRLSRNGAPLLRRLQSSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKRLSRNGAPLLRRLQSSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 LLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 DHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 VVLRQARREVDSIGLEEASGMHLPERPAAAPRRPFSWEDVDRLLDPANRAHLGLEEQLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVLRQARREVDSIGLEEASGMHLPERPAAAPRRPFSWEDVDRLLDPANRAHLGLEEQLRE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 LLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQPLPTGPGLEGFEEDGAALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQPLPTGPGLEGFEEDGAALG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 PEAGEEVLPRLETLLQPRKRSRSTCGDSEVEEESPGKRLDAGLTNGFGGARSEQEPGGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEAGEEVLPRLETLLQPRKRSRSTCGDSEVEEESPGKRLDAGLTNGFGGARSEQEPGGGL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 GRKATPRRRCASESSISSSNSPLCDSSFNAPKCGRGKPALVRRHTLEDRSELISCIENGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRKATPRRRCASESSISSSNSPLCDSSFNAPKCGRGKPALVRRHTLEDRSELISCIENGN
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 YAKAARIAAEVGQSSMWISTDAAASVLEPLKVVWAKCSGYPSYPALIIDPKMPRVPGHHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YAKAARIAAEVGQSSMWISTDAAASVLEPLKVVWAKCSGYPSYPALIIDPKMPRVPGHHN
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 GVTIPAPPLDVLKIGEHMQTKSDEKLFLVLFFDNKRSWQWLPKSKMVPLGIDETIDKLKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVTIPAPPLDVLKIGEHMQTKSDEKLFLVLFFDNKRSWQWLPKSKMVPLGIDETIDKLKM
970 980 990 1000 1010 1020
1030 1040 1050
pF1KB3 MEGRNSSIRKAVRIAFDRAMNHLSRVHGEPTSDLSDID
::::::::::::::::::::::::::::::::::::::
NP_001 MEGRNSSIRKAVRIAFDRAMNHLSRVHGEPTSDLSDID
1030 1040 1050
>>XP_016884209 (OMIM: 604589) PREDICTED: bromodomain-con (955 aa)
initn: 5596 init1: 5381 opt: 5386 Z-score: 4416.2 bits: 828.7 E(85289): 0
Smith-Waterman score: 5386; 86.2% identity (91.2% similar) in 942 aa overlap (1-937:1-936)
10 20 30 40 50 60
pF1KB3 MRRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASALPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASALPEP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 KVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKESSVKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKESSVKTV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 RSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LLKRLSRNGAPLLRRLQSSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKRLSRNGAPLLRRLQSSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 LLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 DHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 VVLRQARREVDSIGLEEASGMHLPERPAAAPRRPFSWEDVDRLLDPANRAHLGLEEQLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVLRQARREVDSIGLEEASGMHLPERPAAAPRRPFSWEDVDRLLDPANRAHLGLEEQLRE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 LLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQPLPTGPGLEGFEEDGAALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQPLPTGPGLEGFEEDGAALG
730 740 750 760 770 780
790 800 810 820 830
pF1KB3 PEAGEEVLPRLETLLQPRKRSRSTCGDSEVEEESPGKR---LDAGLTNGFGGARSEQEPG
:::::: . :.: . . ..::.. : : . :. .. : . ..:
XP_016 PEAGEEG-DKSPPKLEP-SDALPLPSNSETNSEPPTLKPVELNPEQSKLFKRVTFDNESH
790 800 810 820 830
840 850 860 870 880 890
pF1KB3 GGLGRKATPRRRCASESSISSSNSPLCDSSFNA-PKCGRGKPALVRRHTLEDRSELISCI
.. ..: : . ::.. : .: : : .. : .: .:. .:
XP_016 SACTQSALVSGRPPEPTRASSGDVPAAAASAVAEPASDVNR----RTSVLFCKSKSVSPP
840 850 860 870 880 890
900 910 920 930 940 950
pF1KB3 ENGNYAKAARIAAEVGQSS-MWISTDAAASVLEPLKVVWAKCSGYPSYPALIIDPKMPRV
.... ... . ..: .. . . ..:.: : . :
XP_016 KSAKNTETQPTSPQLGTKTFLSVVLPRLETLLQPRKRSRSTCGDSEVEEESPGKRLDAEP
900 910 920 930 940 950
960 970 980 990 1000 1010
pF1KB3 PGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLVLFFDNKRSWQWLPKSKMVPLGIDETI
XP_016 V
>>XP_016884208 (OMIM: 604589) PREDICTED: bromodomain-con (958 aa)
initn: 5604 init1: 5381 opt: 5386 Z-score: 4416.1 bits: 828.7 E(85289): 0
Smith-Waterman score: 5386; 86.2% identity (91.2% similar) in 942 aa overlap (1-937:1-936)
10 20 30 40 50 60
pF1KB3 MRRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASALPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASALPEP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 KVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKESSVKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKESSVKTV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 RSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LLKRLSRNGAPLLRRLQSSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKRLSRNGAPLLRRLQSSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 LLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 DHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 VVLRQARREVDSIGLEEASGMHLPERPAAAPRRPFSWEDVDRLLDPANRAHLGLEEQLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVLRQARREVDSIGLEEASGMHLPERPAAAPRRPFSWEDVDRLLDPANRAHLGLEEQLRE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 LLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQPLPTGPGLEGFEEDGAALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQPLPTGPGLEGFEEDGAALG
730 740 750 760 770 780
790 800 810 820 830
pF1KB3 PEAGEEVLPRLETLLQPRKRSRSTCGDSEVEEESPGKR---LDAGLTNGFGGARSEQEPG
:::::: . :.: . . ..::.. : : . :. .. : . ..:
XP_016 PEAGEEG-DKSPPKLEP-SDALPLPSNSETNSEPPTLKPVELNPEQSKLFKRVTFDNESH
790 800 810 820 830
840 850 860 870 880 890
pF1KB3 GGLGRKATPRRRCASESSISSSNSPLCDSSFNA-PKCGRGKPALVRRHTLEDRSELISCI
.. ..: : . ::.. : .: : : .. : .: .:. .:
XP_016 SACTQSALVSGRPPEPTRASSGDVPAAAASAVAEPASDVNR----RTSVLFCKSKSVSPP
840 850 860 870 880 890
900 910 920 930 940 950
pF1KB3 ENGNYAKAARIAAEVGQSS-MWISTDAAASVLEPLKVVWAKCSGYPSYPALIIDPKMPRV
.... ... . ..: .. . . ..:.: : . :
XP_016 KSAKNTETQPTSPQLGTKTFLSVVLPRLETLLQPRKRSRSTCGDSEVEEESPGKRLDAGS
900 910 920 930 940 950
960 970 980 990 1000 1010
pF1KB3 PGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLVLFFDNKRSWQWLPKSKMVPLGIDETI
XP_016 HFNH
>>XP_016884207 (OMIM: 604589) PREDICTED: bromodomain-con (1023 aa)
initn: 5382 init1: 5382 opt: 5386 Z-score: 4415.8 bits: 828.7 E(85289): 0
Smith-Waterman score: 6907; 96.7% identity (96.7% similar) in 1058 aa overlap (1-1058:1-1023)
10 20 30 40 50 60
pF1KB3 MRRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASALPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASALPEP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 KVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKESSVKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKESSVKTV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 RSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LLKRLSRNGAPLLRRLQSSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKRLSRNGAPLLRRLQSSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 LLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 DHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 VVLRQARREVDSIGLEEASGMHLPERPAAAPRRPFSWEDVDRLLDPANRAHLGLEEQLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVLRQARREVDSIGLEEASGMHLPERPAAAPRRPFSWEDVDRLLDPANRAHLGLEEQLRE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 LLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQPLPTGPGLEGFEEDGAALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQPLPTGPGLEGFEEDGAALG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 PEAGEEVLPRLETLLQPRKRSRSTCGDSEVEEESPGKRLDAGLTNGFGGARSEQEPGGGL
:::::: :::::::::::::::::::
XP_016 PEAGEE-----------------------------------GLTNGFGGARSEQEPGGGL
790 800
850 860 870 880 890 900
pF1KB3 GRKATPRRRCASESSISSSNSPLCDSSFNAPKCGRGKPALVRRHTLEDRSELISCIENGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRKATPRRRCASESSISSSNSPLCDSSFNAPKCGRGKPALVRRHTLEDRSELISCIENGN
810 820 830 840 850 860
910 920 930 940 950 960
pF1KB3 YAKAARIAAEVGQSSMWISTDAAASVLEPLKVVWAKCSGYPSYPALIIDPKMPRVPGHHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YAKAARIAAEVGQSSMWISTDAAASVLEPLKVVWAKCSGYPSYPALIIDPKMPRVPGHHN
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KB3 GVTIPAPPLDVLKIGEHMQTKSDEKLFLVLFFDNKRSWQWLPKSKMVPLGIDETIDKLKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVTIPAPPLDVLKIGEHMQTKSDEKLFLVLFFDNKRSWQWLPKSKMVPLGIDETIDKLKM
930 940 950 960 970 980
1030 1040 1050
pF1KB3 MEGRNSSIRKAVRIAFDRAMNHLSRVHGEPTSDLSDID
::::::::::::::::::::::::::::::::::::::
XP_016 MEGRNSSIRKAVRIAFDRAMNHLSRVHGEPTSDLSDID
990 1000 1010 1020
>>XP_016884204 (OMIM: 604589) PREDICTED: bromodomain-con (1189 aa)
initn: 7202 init1: 5381 opt: 5386 Z-score: 4414.9 bits: 828.7 E(85289): 0
Smith-Waterman score: 6282; 88.0% identity (88.0% similar) in 1090 aa overlap (1-959:1-1090)
10 20 30 40 50 60
pF1KB3 MRRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASALPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASALPEP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 KVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKESSVKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKESSVKTV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 RSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LLKRLSRNGAPLLRRLQSSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKRLSRNGAPLLRRLQSSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 LLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 DHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 VVLRQARREVDSIGLEEASGMHLPERPAAAPRRPFSWEDVDRLLDPANRAHLGLEEQLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVLRQARREVDSIGLEEASGMHLPERPAAAPRRPFSWEDVDRLLDPANRAHLGLEEQLRE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 LLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQPLPTGPGLEGFEEDGAALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQPLPTGPGLEGFEEDGAALG
730 740 750 760 770 780
pF1KB3 PEAGEE------------------------------------------------------
::::::
XP_016 PEAGEEGDKSPPKLEPSDALPLPSNSETNSEPPTLKPVELNPEQSKLFKRVTFDNESHSA
790 800 810 820 830 840
pF1KB3 ------------------------------------------------------------
XP_016 CTQSALVSGRPPEPTRASSGDVPAAAASAVAEPASDVNRRTSVLFCKSKSVSPPKSAKNT
850 860 870 880 890 900
790 800 810 820
pF1KB3 -----------------VLPRLETLLQPRKRSRSTCGDSEVEEESPGKRLDAGLTNGFGG
:::::::::::::::::::::::::::::::::::::::::::
XP_016 ETQPTSPQLGTKTFLSVVLPRLETLLQPRKRSRSTCGDSEVEEESPGKRLDAGLTNGFGG
910 920 930 940 950 960
830 840 850 860 870 880
pF1KB3 ARSEQEPGGGLGRKATPRRRCASESSISSSNSPLCDSSFNAPKCGRGKPALVRRHTLEDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARSEQEPGGGLGRKATPRRRCASESSISSSNSPLCDSSFNAPKCGRGKPALVRRHTLEDR
970 980 990 1000 1010 1020
890 900 910 920 930 940
pF1KB3 SELISCIENGNYAKAARIAAEVGQSSMWISTDAAASVLEPLKVVWAKCSGYPSYPALIID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SELISCIENGNYAKAARIAAEVGQSSMWISTDAAASVLEPLKVVWAKCSGYPSYPALIID
1030 1040 1050 1060 1070 1080
950 960 970 980 990 1000
pF1KB3 PKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLVLFFDNKRSWQWLPKSKMVPL
::::::::::
XP_016 PKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLVLFFDNKRSWQWLPKSKMVPL
1090 1100 1110 1120 1130 1140
>--
initn: 662 init1: 662 opt: 662 Z-score: 547.2 bits: 113.1 E(85289): 9.7e-24
Smith-Waterman score: 662; 100.0% identity (100.0% similar) in 99 aa overlap (960-1058:1091-1189)
930 940 950 960 970 980
pF1KB3 LKVVWAKCSGYPSYPALIIDPKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLV
::::::::::::::::::::::::::::::
XP_016 LKVVWAKCSGYPSYPALIIDPKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLV
1070 1080 1090 1100 1110 1120
990 1000 1010 1020 1030 1040
pF1KB3 LFFDNKRSWQWLPKSKMVPLGIDETIDKLKMMEGRNSSIRKAVRIAFDRAMNHLSRVHGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFFDNKRSWQWLPKSKMVPLGIDETIDKLKMMEGRNSSIRKAVRIAFDRAMNHLSRVHGE
1130 1140 1150 1160 1170 1180
1050
pF1KB3 PTSDLSDID
:::::::::
XP_016 PTSDLSDID
>>XP_016884205 (OMIM: 604589) PREDICTED: bromodomain-con (1189 aa)
initn: 7202 init1: 5381 opt: 5386 Z-score: 4414.9 bits: 828.7 E(85289): 0
Smith-Waterman score: 6282; 88.0% identity (88.0% similar) in 1090 aa overlap (1-959:1-1090)
10 20 30 40 50 60
pF1KB3 MRRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASALPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASALPEP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 KVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKESSVKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKESSVKTV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 RSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LLKRLSRNGAPLLRRLQSSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKRLSRNGAPLLRRLQSSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 LLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 DHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 VVLRQARREVDSIGLEEASGMHLPERPAAAPRRPFSWEDVDRLLDPANRAHLGLEEQLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVLRQARREVDSIGLEEASGMHLPERPAAAPRRPFSWEDVDRLLDPANRAHLGLEEQLRE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 LLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQPLPTGPGLEGFEEDGAALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQPLPTGPGLEGFEEDGAALG
730 740 750 760 770 780
pF1KB3 PEAGEE------------------------------------------------------
::::::
XP_016 PEAGEEGDKSPPKLEPSDALPLPSNSETNSEPPTLKPVELNPEQSKLFKRVTFDNESHSA
790 800 810 820 830 840
pF1KB3 ------------------------------------------------------------
XP_016 CTQSALVSGRPPEPTRASSGDVPAAAASAVAEPASDVNRRTSVLFCKSKSVSPPKSAKNT
850 860 870 880 890 900
790 800 810 820
pF1KB3 -----------------VLPRLETLLQPRKRSRSTCGDSEVEEESPGKRLDAGLTNGFGG
:::::::::::::::::::::::::::::::::::::::::::
XP_016 ETQPTSPQLGTKTFLSVVLPRLETLLQPRKRSRSTCGDSEVEEESPGKRLDAGLTNGFGG
910 920 930 940 950 960
830 840 850 860 870 880
pF1KB3 ARSEQEPGGGLGRKATPRRRCASESSISSSNSPLCDSSFNAPKCGRGKPALVRRHTLEDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARSEQEPGGGLGRKATPRRRCASESSISSSNSPLCDSSFNAPKCGRGKPALVRRHTLEDR
970 980 990 1000 1010 1020
890 900 910 920 930 940
pF1KB3 SELISCIENGNYAKAARIAAEVGQSSMWISTDAAASVLEPLKVVWAKCSGYPSYPALIID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SELISCIENGNYAKAARIAAEVGQSSMWISTDAAASVLEPLKVVWAKCSGYPSYPALIID
1030 1040 1050 1060 1070 1080
950 960 970 980 990 1000
pF1KB3 PKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLVLFFDNKRSWQWLPKSKMVPL
::::::::::
XP_016 PKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLVLFFDNKRSWQWLPKSKMVPL
1090 1100 1110 1120 1130 1140
>--
initn: 662 init1: 662 opt: 662 Z-score: 547.2 bits: 113.1 E(85289): 9.7e-24
Smith-Waterman score: 662; 100.0% identity (100.0% similar) in 99 aa overlap (960-1058:1091-1189)
930 940 950 960 970 980
pF1KB3 LKVVWAKCSGYPSYPALIIDPKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLV
::::::::::::::::::::::::::::::
XP_016 LKVVWAKCSGYPSYPALIIDPKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLV
1070 1080 1090 1100 1110 1120
990 1000 1010 1020 1030 1040
pF1KB3 LFFDNKRSWQWLPKSKMVPLGIDETIDKLKMMEGRNSSIRKAVRIAFDRAMNHLSRVHGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFFDNKRSWQWLPKSKMVPLGIDETIDKLKMMEGRNSSIRKAVRIAFDRAMNHLSRVHGE
1130 1140 1150 1160 1170 1180
1050
pF1KB3 PTSDLSDID
:::::::::
XP_016 PTSDLSDID
>>XP_016884206 (OMIM: 604589) PREDICTED: bromodomain-con (1189 aa)
initn: 7202 init1: 5381 opt: 5386 Z-score: 4414.9 bits: 828.7 E(85289): 0
Smith-Waterman score: 6282; 88.0% identity (88.0% similar) in 1090 aa overlap (1-959:1-1090)
10 20 30 40 50 60
pF1KB3 MRRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASALPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASALPEP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 KVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKESSVKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKESSVKTV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 RSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LLKRLSRNGAPLLRRLQSSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKRLSRNGAPLLRRLQSSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 LLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 DHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 VVLRQARREVDSIGLEEASGMHLPERPAAAPRRPFSWEDVDRLLDPANRAHLGLEEQLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVLRQARREVDSIGLEEASGMHLPERPAAAPRRPFSWEDVDRLLDPANRAHLGLEEQLRE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 LLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQPLPTGPGLEGFEEDGAALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQPLPTGPGLEGFEEDGAALG
730 740 750 760 770 780
pF1KB3 PEAGEE------------------------------------------------------
::::::
XP_016 PEAGEEGDKSPPKLEPSDALPLPSNSETNSEPPTLKPVELNPEQSKLFKRVTFDNESHSA
790 800 810 820 830 840
pF1KB3 ------------------------------------------------------------
XP_016 CTQSALVSGRPPEPTRASSGDVPAAAASAVAEPASDVNRRTSVLFCKSKSVSPPKSAKNT
850 860 870 880 890 900
790 800 810 820
pF1KB3 -----------------VLPRLETLLQPRKRSRSTCGDSEVEEESPGKRLDAGLTNGFGG
:::::::::::::::::::::::::::::::::::::::::::
XP_016 ETQPTSPQLGTKTFLSVVLPRLETLLQPRKRSRSTCGDSEVEEESPGKRLDAGLTNGFGG
910 920 930 940 950 960
830 840 850 860 870 880
pF1KB3 ARSEQEPGGGLGRKATPRRRCASESSISSSNSPLCDSSFNAPKCGRGKPALVRRHTLEDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARSEQEPGGGLGRKATPRRRCASESSISSSNSPLCDSSFNAPKCGRGKPALVRRHTLEDR
970 980 990 1000 1010 1020
890 900 910 920 930 940
pF1KB3 SELISCIENGNYAKAARIAAEVGQSSMWISTDAAASVLEPLKVVWAKCSGYPSYPALIID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SELISCIENGNYAKAARIAAEVGQSSMWISTDAAASVLEPLKVVWAKCSGYPSYPALIID
1030 1040 1050 1060 1070 1080
950 960 970 980 990 1000
pF1KB3 PKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLVLFFDNKRSWQWLPKSKMVPL
::::::::::
XP_016 PKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLVLFFDNKRSWQWLPKSKMVPL
1090 1100 1110 1120 1130 1140
>--
initn: 662 init1: 662 opt: 662 Z-score: 547.2 bits: 113.1 E(85289): 9.7e-24
Smith-Waterman score: 662; 100.0% identity (100.0% similar) in 99 aa overlap (960-1058:1091-1189)
930 940 950 960 970 980
pF1KB3 LKVVWAKCSGYPSYPALIIDPKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLV
::::::::::::::::::::::::::::::
XP_016 LKVVWAKCSGYPSYPALIIDPKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLV
1070 1080 1090 1100 1110 1120
990 1000 1010 1020 1030 1040
pF1KB3 LFFDNKRSWQWLPKSKMVPLGIDETIDKLKMMEGRNSSIRKAVRIAFDRAMNHLSRVHGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFFDNKRSWQWLPKSKMVPLGIDETIDKLKMMEGRNSSIRKAVRIAFDRAMNHLSRVHGE
1130 1140 1150 1160 1170 1180
1050
pF1KB3 PTSDLSDID
:::::::::
XP_016 PTSDLSDID
>>NP_001291737 (OMIM: 604589) bromodomain-containing pro (1189 aa)
initn: 7202 init1: 5381 opt: 5386 Z-score: 4414.9 bits: 828.7 E(85289): 0
Smith-Waterman score: 6282; 88.0% identity (88.0% similar) in 1090 aa overlap (1-959:1-1090)
10 20 30 40 50 60
pF1KB3 MRRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASALPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASALPEP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 KVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKESSVKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKESSVKTV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 RSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LLKRLSRNGAPLLRRLQSSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKRLSRNGAPLLRRLQSSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 LLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 DHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 VVLRQARREVDSIGLEEASGMHLPERPAAAPRRPFSWEDVDRLLDPANRAHLGLEEQLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVLRQARREVDSIGLEEASGMHLPERPAAAPRRPFSWEDVDRLLDPANRAHLGLEEQLRE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 LLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQPLPTGPGLEGFEEDGAALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQPLPTGPGLEGFEEDGAALG
730 740 750 760 770 780
pF1KB3 PEAGEE------------------------------------------------------
::::::
NP_001 PEAGEEGDKSPPKLEPSDALPLPSNSETNSEPPTLKPVELNPEQSKLFKRVTFDNESHSA
790 800 810 820 830 840
pF1KB3 ------------------------------------------------------------
NP_001 CTQSALVSGRPPEPTRASSGDVPAAAASAVAEPASDVNRRTSVLFCKSKSVSPPKSAKNT
850 860 870 880 890 900
790 800 810 820
pF1KB3 -----------------VLPRLETLLQPRKRSRSTCGDSEVEEESPGKRLDAGLTNGFGG
:::::::::::::::::::::::::::::::::::::::::::
NP_001 ETQPTSPQLGTKTFLSVVLPRLETLLQPRKRSRSTCGDSEVEEESPGKRLDAGLTNGFGG
910 920 930 940 950 960
830 840 850 860 870 880
pF1KB3 ARSEQEPGGGLGRKATPRRRCASESSISSSNSPLCDSSFNAPKCGRGKPALVRRHTLEDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARSEQEPGGGLGRKATPRRRCASESSISSSNSPLCDSSFNAPKCGRGKPALVRRHTLEDR
970 980 990 1000 1010 1020
890 900 910 920 930 940
pF1KB3 SELISCIENGNYAKAARIAAEVGQSSMWISTDAAASVLEPLKVVWAKCSGYPSYPALIID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SELISCIENGNYAKAARIAAEVGQSSMWISTDAAASVLEPLKVVWAKCSGYPSYPALIID
1030 1040 1050 1060 1070 1080
950 960 970 980 990 1000
pF1KB3 PKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLVLFFDNKRSWQWLPKSKMVPL
::::::::::
NP_001 PKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLVLFFDNKRSWQWLPKSKMVPL
1090 1100 1110 1120 1130 1140
>--
initn: 662 init1: 662 opt: 662 Z-score: 547.2 bits: 113.1 E(85289): 9.7e-24
Smith-Waterman score: 662; 100.0% identity (100.0% similar) in 99 aa overlap (960-1058:1091-1189)
930 940 950 960 970 980
pF1KB3 LKVVWAKCSGYPSYPALIIDPKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLV
::::::::::::::::::::::::::::::
NP_001 LKVVWAKCSGYPSYPALIIDPKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLV
1070 1080 1090 1100 1110 1120
990 1000 1010 1020 1030 1040
pF1KB3 LFFDNKRSWQWLPKSKMVPLGIDETIDKLKMMEGRNSSIRKAVRIAFDRAMNHLSRVHGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFFDNKRSWQWLPKSKMVPLGIDETIDKLKMMEGRNSSIRKAVRIAFDRAMNHLSRVHGE
1130 1140 1150 1160 1170 1180
1050
pF1KB3 PTSDLSDID
:::::::::
NP_001 PTSDLSDID
>>XP_016884210 (OMIM: 604589) PREDICTED: bromodomain-con (941 aa)
initn: 5381 init1: 5381 opt: 5383 Z-score: 4413.8 bits: 828.2 E(85289): 0
Smith-Waterman score: 5383; 99.2% identity (99.4% similar) in 795 aa overlap (1-792:1-795)
10 20 30 40 50 60
pF1KB3 MRRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASALPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASALPEP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 KVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKESSVKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKESSVKTV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 RSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LLKRLSRNGAPLLRRLQSSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKRLSRNGAPLLRRLQSSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 LLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 DHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 VVLRQARREVDSIGLEEASGMHLPERPAAAPRRPFSWEDVDRLLDPANRAHLGLEEQLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVLRQARREVDSIGLEEASGMHLPERPAAAPRRPFSWEDVDRLLDPANRAHLGLEEQLRE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 LLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQPLPTGPGLEGFEEDGAALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQPLPTGPGLEGFEEDGAALG
730 740 750 760 770 780
790 800 810 820 830
pF1KB3 PEAGEE---VLPRLETLLQPRKRSRSTCGDSEVEEESPGKRLDAGLTNGFGGARSEQEPG
:::::: :.::
XP_016 PEAGEEGDKSPPKLEPSDALPLPSNSETNSEPPTLKPVELNPEQSKLFKRVTFDNESHSA
790 800 810 820 830 840
>>XP_016884203 (OMIM: 604589) PREDICTED: bromodomain-con (1187 aa)
initn: 5664 init1: 3843 opt: 5361 Z-score: 4394.5 bits: 825.0 E(85289): 0
Smith-Waterman score: 6272; 87.8% identity (87.8% similar) in 1092 aa overlap (1-961:1-1090)
10 20 30 40 50 60
pF1KB3 MRRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASALPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASALPEP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 KVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKESSVKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKESSVKTV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 RSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LLKRLSRNGAPLLRRLQSSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKRLSRNGAPLLRRLQSSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 LLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYL
::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRKREKLKREQV--EQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYL
550 560 570 580 590
610 620 630 640 650 660
pF1KB3 DHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGG
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 VVLRQARREVDSIGLEEASGMHLPERPAAAPRRPFSWEDVDRLLDPANRAHLGLEEQLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVLRQARREVDSIGLEEASGMHLPERPAAAPRRPFSWEDVDRLLDPANRAHLGLEEQLRE
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 LLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQPLPTGPGLEGFEEDGAALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQPLPTGPGLEGFEEDGAALG
720 730 740 750 760 770
pF1KB3 PEAGEE------------------------------------------------------
::::::
XP_016 PEAGEEGDKSPPKLEPSDALPLPSNSETNSEPPTLKPVELNPEQSKLFKRVTFDNESHSA
780 790 800 810 820 830
pF1KB3 ------------------------------------------------------------
XP_016 CTQSALVSGRPPEPTRASSGDVPAAAASAVAEPASDVNRRTSVLFCKSKSVSPPKSAKNT
840 850 860 870 880 890
790 800 810 820
pF1KB3 -----------------VLPRLETLLQPRKRSRSTCGDSEVEEESPGKRLDAGLTNGFGG
:::::::::::::::::::::::::::::::::::::::::::
XP_016 ETQPTSPQLGTKTFLSVVLPRLETLLQPRKRSRSTCGDSEVEEESPGKRLDAGLTNGFGG
900 910 920 930 940 950
830 840 850 860 870 880
pF1KB3 ARSEQEPGGGLGRKATPRRRCASESSISSSNSPLCDSSFNAPKCGRGKPALVRRHTLEDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARSEQEPGGGLGRKATPRRRCASESSISSSNSPLCDSSFNAPKCGRGKPALVRRHTLEDR
960 970 980 990 1000 1010
890 900 910 920 930 940
pF1KB3 SELISCIENGNYAKAARIAAEVGQSSMWISTDAAASVLEPLKVVWAKCSGYPSYPALIID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SELISCIENGNYAKAARIAAEVGQSSMWISTDAAASVLEPLKVVWAKCSGYPSYPALIID
1020 1030 1040 1050 1060 1070
950 960 970 980 990 1000
pF1KB3 PKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLVLFFDNKRSWQWLPKSKMVPL
::::::::::::
XP_016 PKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLVLFFDNKRSWQWLPKSKMVPL
1080 1090 1100 1110 1120 1130
>--
initn: 647 init1: 647 opt: 647 Z-score: 534.9 bits: 110.8 E(85289): 4.7e-23
Smith-Waterman score: 647; 100.0% identity (100.0% similar) in 97 aa overlap (962-1058:1091-1187)
940 950 960 970 980 990
pF1KB3 VVWAKCSGYPSYPALIIDPKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLVLF
::::::::::::::::::::::::::::::
XP_016 VVWAKCSGYPSYPALIIDPKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLVLF
1070 1080 1090 1100 1110 1120
1000 1010 1020 1030 1040 1050
pF1KB3 FDNKRSWQWLPKSKMVPLGIDETIDKLKMMEGRNSSIRKAVRIAFDRAMNHLSRVHGEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDNKRSWQWLPKSKMVPLGIDETIDKLKMMEGRNSSIRKAVRIAFDRAMNHLSRVHGEPT
1130 1140 1150 1160 1170 1180
pF1KB3 SDLSDID
:::::::
XP_016 SDLSDID
1058 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 02:47:29 2016 done: Fri Nov 4 02:47:31 2016
Total Scan time: 10.980 Total Display time: 0.420
Function used was FASTA [36.3.4 Apr, 2011]