Result of FASTA (ccds) for
pF1KB3946
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3946, 509 aa
1>>>pF1KB3946 509 - 509 aa - 509 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.4518+/-0.00113; mu= -9.4765+/- 0.069
mean_var=554.8741+/-114.288, 0's: 0 Z-trim(117.0): 42 B-trim: 493 in 1/52
Lambda= 0.054447
statistics sampled from 17686 (17727) to 17686 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.805), E-opt: 0.2 (0.545), width: 16
Scan time: 4.080
The best scores are: opt bits E(32554)
CCDS11689.1 SOX9 gene_id:6662|Hs108|chr17 ( 509) 3554 293.5 3.7e-79
CCDS13964.1 SOX10 gene_id:6663|Hs108|chr22 ( 466) 1350 120.3 4.6e-27
CCDS10428.1 SOX8 gene_id:30812|Hs108|chr16 ( 446) 1178 106.8 5.2e-23
>>CCDS11689.1 SOX9 gene_id:6662|Hs108|chr17 (509 aa)
initn: 3554 init1: 3554 opt: 3554 Z-score: 1534.6 bits: 293.5 E(32554): 3.7e-79
Smith-Waterman score: 3554; 100.0% identity (100.0% similar) in 509 aa overlap (1-509:1-509)
10 20 30 40 50 60
pF1KB3 MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 KKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 KKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAAR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 RKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 RKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 SVKNGQAEAEEATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPTPPTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SVKNGQAEAEEATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPTPPTT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 PKTDVQPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PKTDVQPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 NGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 NGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 QPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQIAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 QPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQIAY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 SPFNLPHYSPSYPPITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPAQRPMYTPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SPFNLPHYSPSYPPITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPAQRPMYTPI
430 440 450 460 470 480
490 500
pF1KB3 ADTSGVPSIPQTHSPQHWEQPVYTQLTRP
:::::::::::::::::::::::::::::
CCDS11 ADTSGVPSIPQTHSPQHWEQPVYTQLTRP
490 500
>>CCDS13964.1 SOX10 gene_id:6663|Hs108|chr22 (466 aa)
initn: 1439 init1: 805 opt: 1350 Z-score: 599.4 bits: 120.3 E(32554): 4.6e-27
Smith-Waterman score: 1682; 54.4% identity (72.1% similar) in 502 aa overlap (13-509:18-466)
10 20 30 40 50
pF1KB3 MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPK
:. . :: . .:... :..:. ::: . . . :
CCDS13 MAEEQDLSEVELSPVGSEEPRCLSPGSAPSLGPDGGGG----GSGLRASPGPGELGKVKK
10 20 30 40 50
60 70 80 90 100 110
pF1KB3 GEPDLKKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVW
. : :...:::::::::::::::.:::::::::::::::.::.::::::::::::::
CCDS13 EQQD--GEADDDKFPVCIREAVSQVLSGYDWTLVPMPVRVNGASKSKPHVKRPMNAFMVW
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB3 AQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQ
::::::::::::::::::::::::::::::::::.::::.:::::::.::::::::::::
CCDS13 AQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKYQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB3 PRRRKSVKNGQAEAE----EATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEH-SGQ
:::::. : .:.::: :: . . .: .:. . : : . : . :: :::
CCDS13 PRRRKNGKAAQGEAECPGGEAEQGGTAAIQAHYKSAHLDHRHPGEGSPMSDGNPEHPSGQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB3 SQGPPTPPTTPKTDVQPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFD
:.:::::::::::..: :::: ::.:: . :::. : ::: .:::::.: .:.::.::::
CCDS13 SHGPPTPPTTPKTELQSGKADPKRDGRSMGEGGK-PHIDFGNVDIGEISHEVMSNMETFD
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB3 VNEFDQYLPPNGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPP
: :.::::::::::: : . ...::..:. :. ::. .:.:: :: :
CCDS13 VAELDQYLPPNGHPG----HVSSYSAAGYGLGSALAV-ASGHSAWISK----PPGVALPT
300 310 320 330 340
360 370 380 390 400 410
pF1KB3 QAPPAPQAPPQPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQ
.::. .: : .. .: :: .: ::..:
CCDS13 VSPPGVDAKAQVKTE-----TAGPQ---------------------------GPPHYTDQ
350 360 370
420 430 440 450 460 470
pF1KB3 QQHSPQQIAYSPFNLPHYSPSYPPITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMN
: .::::. ..::::. ..: :.: :.::.::: :. ::.:. ::..::::.:.::.
CCDS13 P--STSQIAYTSLSLPHYGSAFPSISRPQFDYSDHQPSGPYYGHS-GQASGLYSAFSYMG
380 390 400 410 420
480 490 500
pF1KB3 PAQRPMYTPIADTSGVPSIPQTHSPQHWEQPVYTQLTRP
:.:::.:: :.: : :: ::.::: :::::::: :.::
CCDS13 PSQRPLYTAISDPS--PSGPQSHSPTHWEQPVYTTLSRP
430 440 450 460
>>CCDS10428.1 SOX8 gene_id:30812|Hs108|chr16 (446 aa)
initn: 1081 init1: 586 opt: 1178 Z-score: 526.6 bits: 106.8 E(32554): 5.2e-23
Smith-Waterman score: 1339; 48.8% identity (67.6% similar) in 500 aa overlap (19-509:16-446)
10 20 30 40 50
pF1KB3 MNLLDPFMKMTDEQEKGLSG-APSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPD
:: : : . ::: .. :: .::. . .:.:
CCDS10 MLDMSEARSQPPCSPSGTASSMSHVEDSDSDAPPSPAGSEGLGRAGVAVGGARGDP-
10 20 30 40 50
60 70 80 90 100 110
pF1KB3 LKKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSS--KNKPHVKRPMNAFMVWAQ
:. ...::.:::.:::::::::::.::::::: .:.. : ::::::::::::::::
CCDS10 --AEAADERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGALKAKPHVKRPMNAFMVWAQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB3 AARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPR
:::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
CCDS10 AARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB3 RRKSVKNGQAEAEEATEQ-THISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPT
::::.: :..... ..: : . .:..:: .:... : :.:.::..::::
CCDS10 RRKSAKAGHSDSDSGAELGPHPGGGAVYKA--------EAGLGDGHHHGDHTGQTHGPPT
180 190 200 210 220
240 250 260 270 280 290
pF1KB3 PPTTPKTDVQPG--KADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEF
:::::::..: . : .:: ::: ..::: ::: .:::.::::.:......:::.::
CCDS10 PPTTPKTELQQAGAKPELKLEGRRPVDSGRQN-IDFSNVDISELSSEVMGTMDAFDVHEF
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB3 DQYLPPNGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPP
::::: .: :. : ::. : :.: :.:. :: :. :: .: :
CCDS10 DQYLPLGG-PA-PPEPGQA-YGGAY-------FHAGASPVWAHKS-APSA------SASP
290 300 310 320
360 370 380 390 400 410
pF1KB3 APQAPPQPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHS
. .::.: :::::: ::.::..: . :
CCDS10 TETGPPRP---------------------------------HIKTEQPSPGHYGDQPRGS
330 340 350
420 430 440 450 460 470
pF1KB3 PQQIAYSPFNLPHYSPSYP--PITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPA
:. . : . .:. : :.. :: :: : : .::::. : . :::. . .:
CCDS10 PDYGSCS--GQSSATPAAPAGPFAGSQGDYGDLQ-ASSYYGAYPGYAPGLYQYPCFHSP-
360 370 380 390 400 410
480 490 500
pF1KB3 QRPMYTPIADTSGVPSIPQTHSP-QHWEQPVYTQLTRP
.::. .:. . :. ..: .::: .::.::::: ::::
CCDS10 RRPYASPLLN--GL-ALPPAHSPTSHWDQPVYTTLTRP
420 430 440
509 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 14:11:31 2016 done: Thu Nov 3 14:11:31 2016
Total Scan time: 4.080 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]