Result of FASTA (omim) for
pF1KB3889
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3889, 808 aa
1>>>pF1KB3889 808 - 808 aa - 808 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0950+/-0.000499; mu= 17.5124+/- 0.031
mean_var=209.5912+/-45.597, 0's: 0 Z-trim(112.9): 388 B-trim: 81 in 1/52
Lambda= 0.088591
statistics sampled from 21506 (22024) to 21506 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.61), E-opt: 0.2 (0.258), width: 16
Scan time: 13.310
The best scores are: opt bits E(85289)
NP_006444 (OMIM: 605915) transducin beta-like prot ( 808) 5416 706.9 9.1e-203
NP_006775 (OMIM: 604737) WD repeat-containing prot ( 943) 363 61.1 2.5e-08
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 328 56.0 3.2e-07
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 328 56.0 3.2e-07
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 328 56.0 3.2e-07
NP_942593 (OMIM: 610767,611081) autophagy-related ( 444) 323 55.5 5.9e-07
XP_005246143 (OMIM: 610767,611081) PREDICTED: auto ( 463) 323 55.6 6e-07
XP_005246141 (OMIM: 610767,611081) PREDICTED: auto ( 480) 323 55.6 6.1e-07
NP_001177196 (OMIM: 610767,611081) autophagy-relat ( 491) 323 55.6 6.2e-07
NP_001177195 (OMIM: 610767,611081) autophagy-relat ( 523) 323 55.6 6.4e-07
XP_006712671 (OMIM: 610767,611081) PREDICTED: auto ( 540) 323 55.7 6.5e-07
NP_060444 (OMIM: 610767,611081) autophagy-related ( 588) 323 55.7 6.8e-07
NP_110430 (OMIM: 610767,611081) autophagy-related ( 607) 323 55.7 6.9e-07
XP_005246139 (OMIM: 610767,611081) PREDICTED: auto ( 624) 323 55.8 7e-07
NP_620640 (OMIM: 601787) transcription initiation ( 745) 323 55.9 7.8e-07
XP_016880191 (OMIM: 601545,607432) PREDICTED: plat ( 345) 317 54.6 8.7e-07
XP_016880190 (OMIM: 601545,607432) PREDICTED: plat ( 410) 317 54.7 9.6e-07
NP_000421 (OMIM: 601545,607432) platelet-activatin ( 410) 317 54.7 9.6e-07
XP_016880189 (OMIM: 601545,607432) PREDICTED: plat ( 410) 317 54.7 9.6e-07
XP_016880188 (OMIM: 601545,607432) PREDICTED: plat ( 410) 317 54.7 9.6e-07
XP_011522204 (OMIM: 601545,607432) PREDICTED: plat ( 428) 317 54.7 9.8e-07
XP_011522205 (OMIM: 601545,607432) PREDICTED: plat ( 428) 317 54.7 9.8e-07
XP_011522203 (OMIM: 601545,607432) PREDICTED: plat ( 428) 317 54.7 9.8e-07
XP_016860387 (OMIM: 612173) PREDICTED: sperm-assoc ( 390) 308 53.5 2.1e-06
NP_387449 (OMIM: 605651) F-box/WD repeat-containin ( 508) 309 53.8 2.2e-06
XP_016864770 (OMIM: 605651) PREDICTED: F-box/WD re ( 510) 309 53.8 2.2e-06
XP_016864769 (OMIM: 605651) PREDICTED: F-box/WD re ( 510) 309 53.8 2.2e-06
XP_005265915 (OMIM: 605651) PREDICTED: F-box/WD re ( 510) 309 53.8 2.2e-06
XP_005265914 (OMIM: 605651) PREDICTED: F-box/WD re ( 515) 309 53.8 2.2e-06
NP_387448 (OMIM: 605651) F-box/WD repeat-containin ( 529) 309 53.9 2.2e-06
XP_005265913 (OMIM: 605651) PREDICTED: F-box/WD re ( 531) 309 53.9 2.2e-06
NP_036432 (OMIM: 605651) F-box/WD repeat-containin ( 542) 309 53.9 2.3e-06
XP_016864768 (OMIM: 605651) PREDICTED: F-box/WD re ( 542) 309 53.9 2.3e-06
XP_005265912 (OMIM: 605651) PREDICTED: F-box/WD re ( 563) 309 53.9 2.3e-06
NP_001290177 (OMIM: 609540) WD repeat-containing p ( 212) 303 52.5 2.3e-06
XP_016860385 (OMIM: 612173) PREDICTED: sperm-assoc ( 512) 308 53.7 2.4e-06
XP_016860386 (OMIM: 612173) PREDICTED: sperm-assoc ( 512) 308 53.7 2.4e-06
XP_011510126 (OMIM: 612173) PREDICTED: sperm-assoc ( 520) 308 53.7 2.4e-06
XP_011510125 (OMIM: 612173) PREDICTED: sperm-assoc ( 528) 308 53.7 2.4e-06
XP_011510124 (OMIM: 612173) PREDICTED: sperm-assoc ( 528) 308 53.7 2.4e-06
XP_011510123 (OMIM: 612173) PREDICTED: sperm-assoc ( 537) 308 53.7 2.5e-06
XP_011510121 (OMIM: 612173) PREDICTED: sperm-assoc ( 577) 308 53.8 2.6e-06
XP_011510120 (OMIM: 612173) PREDICTED: sperm-assoc ( 577) 308 53.8 2.6e-06
XP_011510119 (OMIM: 612173) PREDICTED: sperm-assoc ( 582) 308 53.8 2.6e-06
XP_011510117 (OMIM: 612173) PREDICTED: sperm-assoc ( 592) 308 53.8 2.6e-06
XP_011510118 (OMIM: 612173) PREDICTED: sperm-assoc ( 592) 308 53.8 2.6e-06
XP_011510116 (OMIM: 612173) PREDICTED: sperm-assoc ( 600) 308 53.8 2.6e-06
NP_078808 (OMIM: 612173) sperm-associated antigen ( 631) 308 53.9 2.7e-06
NP_079510 (OMIM: 609540) WD repeat-containing prot ( 305) 303 52.7 2.8e-06
XP_011520396 (OMIM: 609540) PREDICTED: WD repeat-c ( 305) 303 52.7 2.8e-06
>>NP_006444 (OMIM: 605915) transducin beta-like protein (808 aa)
initn: 5416 init1: 5416 opt: 5416 Z-score: 3761.3 bits: 706.9 E(85289): 9.1e-203
Smith-Waterman score: 5416; 99.8% identity (99.9% similar) in 808 aa overlap (1-808:1-808)
10 20 30 40 50 60
pF1KB3 MAETAAGVGRFKTNYAVERKIEPFYKGGKAQLDQTGQHLFCVCGTRVNILEVASGAVLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MAETAAGVGRFKTNYAVERKIEPFYKGGKAQLDQTGQHLFCVCGTRVNILEVASGAVLRS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LEQEDQEDITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LEQEDQEDITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 STLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 STLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 SLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 AAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGRELTHCTL
::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
NP_006 AAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGQELTHCTL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 AHTAGVVLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AHTAGVVLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 VFELQTSACQILHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VFELQTSACQILHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 THSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLPKNTAPDNGPILLQAQTTQRCHDK
:::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::
NP_006 THSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 DINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 ADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 LDAHEDKVWGLHCSRLDDHALTGASDSRVILWKDVTEAEQAEEQARQEEQVVRQQELDNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LDAHEDKVWGLHCSRLDDHALTGASDSRVILWKDVTEAEQAEEQARQEEQVVRQQELDNL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 LHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPEACEKLEATMLRLRRDQKEALLRFCVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPEACEKLEATMLRLRRDQKEALLRFCVT
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 WNTNSRHCHEAQAVLGVLLRREAPEELLAYEGVRAALEALLPYTERHFQRLSRTLQAAAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 WNTNSRHCHEAQAVLGVLLRREAPEELLAYEGVRAALEALLPYTERHFQRLSRTLQAAAF
730 740 750 760 770 780
790 800
pF1KB3 LDFLWHNMKLPVPAAAPTPWETHKGALP
::::::::::::::::::::::::::::
NP_006 LDFLWHNMKLPVPAAAPTPWETHKGALP
790 800
>>NP_006775 (OMIM: 604737) WD repeat-containing protein (943 aa)
initn: 558 init1: 327 opt: 363 Z-score: 270.4 bits: 61.1 E(85289): 2.5e-08
Smith-Waterman score: 448; 21.9% identity (52.3% similar) in 702 aa overlap (57-656:60-732)
30 40 50 60 70 80
pF1KB3 GGKAQLDQTGQHLFCVCGTRVNILEVASGAVLRSLEQEDQEDITAFDLSPDNEVLVTASR
.:..:.:: .: . :::. :... .
NP_006 TLRGEKGRYVAVPACEHVFIWDLRKGEKILILQGLKQE----VTCLCPSPDGLHLAVGYE
30 40 50 60 70 80
90 100 110 120 130 140
pF1KB3 --ALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGT
.. . . ::.:: : : ..:. .: . ::.:. : . :::.. . :
NP_006 DGSIRIFSLLSGEGNVTF---NGHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGL
90 100 110 120 130 140
150 160 170 180 190 200
pF1KB3 HHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFS
....: .. . : . . :: .:. :. .. :.:. . :. ....: . : .:..
NP_006 YRLKGHKDAITQALFLREKN--LLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLL
150 160 170 180 190 200
210 220 230 240 250 260
pF1KB3 ADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEP-VSQLGVKSPGLYFL
.. . ..... :. .:: . .. .: :::: ... .:::.
NP_006 SEEKRLITGASDSELRVWD---------IAYLQEIED----PEEPDPKKIKGSSPGIQDT
210 220 230 240
270 280 290 300 310 320
pF1KB3 TAGDQGTLRVWEAASGQCVYTQAQPP--GPGRE-LTHCTLAHTAGVVLTATADHNLLLYE
...:.... :: . . . ::. ... .. .:. .. .: : :.
NP_006 LEAEDGAFETDEAPEDRILSCRKAGSIMREGRDRVVNLAVDKTGRILACHGTDSVLELFC
250 260 270 280 290 300
330 340
pF1KB3 ARSLR-LQKQF----------------AGYSEE---------------VLDVRFLGPEDS
: . .::.. : :. : ... . :
NP_006 ILSKKEIQKKMDKKMKKARKKAKLHSSKGEEEDPEVNVEMSLQDEIQRVTNIKTSAKIKS
310 320 330 340 350 360
350 360 370 380
pF1KB3 HVVVASNSPCLK-VFELQTSACQI-------------------LHGHTDIVLALDVFRKG
.. : :: :: ::.. .. . :: . : .:. .
NP_006 FDLIHSPHGELKAVFLLQNNLVELYSLNPSLPTPQPVRTSRITIGGHRSDVRTLSFSSDN
370 380 390 400 410 420
390 400 410
pF1KB3 WLFASCAKDQSVRIWRMN-----------------------------KAGQVMCVAQGSG
: : : :..:: . :.:... .::
NP_006 IAVLSAAAD-SIKIWNRSTLQCIRTMTCEYALCSFFVPGDRQVVIGTKTGKLQLYDLASG
430 440 450 460 470 480
420 430 440 450 460 470
pF1KB3 --------HTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLPKNTAPDNGPILLQA
: .. .. : ...: :::. : .::.: . :. ... .. . :.
NP_006 NLLETIDAHDGALWSMSLSPDQRGF-VTGGADKSVKFWDF--ELVKDENSTQKRLSVKQT
490 500 510 520 530 540
480 490 500 510 520 530
pF1KB3 QTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSP
.: : :.:. :. .::.::::.. : :.:.. . ... . ::. . :...:
NP_006 RTLQ--LDEDVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISH
550 560 570 580 590 600
540 550 560 570 580 590
pF1KB3 MDQVLATASADGTIKLWALQDFS-CLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLW
..::.::: ..:.:.: ::. : :.. .:: ::. . :: .. ....:.: .: :
NP_006 DGALIATGSADRNVKIWGL-DFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQW
610 620 630 640 650 660
600 610 620 630 640
pF1KB3 TIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILWKD------VTEAEQAEEQ
. : ..::..:....: : : :...... :. . ::. . : .. :..
NP_006 DADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLWERTREPLILEEEREMERE
670 680 690 700 710 720
650 660 670 680 690 700
pF1KB3 ARQEEQVVRQQELDNLLHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPEACEKLEATML
:. ::.:.....
NP_006 AEYEESVAKEDQPAVPGETQGDSYFTGKKTIETVKAAERIMEAIELYREETAKMKEHKAI
730 740 750 760 770 780
>>NP_060058 (OMIM: 609012) WD repeat-containing protein (334 aa)
initn: 574 init1: 297 opt: 328 Z-score: 250.6 bits: 56.0 E(85289): 3.2e-07
Smith-Waterman score: 367; 24.0% identity (58.6% similar) in 304 aa overlap (106-404:42-331)
80 90 100 110 120 130
pF1KB3 PDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGGCDGAVRV
: :: :... :.:.. ::... : ...
NP_060 AARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKI
20 30 40 50 60 70
140 150 160 170 180 190
pF1KB3 WDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTAHY
: . . : . ::. : . :: :.. : ....:.... .:: .: .:
NP_060 WGAYDGKFEKTISGHKLGISDVAWSSDSN--LLVSASDDKTLKIWDVSSGKCLKTLKGHS
80 90 100 110 120
200 210 220 230 240 250
pF1KB3 SAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEPVSQLGV
. : :. ... ..:.. :. :::... . .:.:. .::: .
NP_060 NYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHS----------DPVSAVHF
130 140 150 160 170
260 270 280 290 300 310
pF1KB3 KSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGRELTHCTLAHTAGVVLTATADHN
. : ..... .: :.:..:::::. : . .: .. .. .. .:.:: :..
NP_060 NRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNP--PVSFVKFSPNGKYILAATLDNT
180 190 200 210 220 230
320 330 340 350 360 370
pF1KB3 LLLYEARSLRLQKQFAGYSEEVLDV--RFLGPEDSHVVVASNSPCLKVFELQTSA-CQIL
: :.. . . : ..:...: . : . .: .:.. . ...:::. : :
NP_060 LKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKL
240 250 260 270 280 290
380 390 400 410 420 430
pF1KB3 HGHTDIVLALDVFRKGWLFASCA--KDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCS
.::::.:.. ..:: : .:.....:.
NP_060 QGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC
300 310 320 330
440 450 460 470 480 490
pF1KB3 RLKESFLVTGSQDCTVKLWPLPKALLPKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPN
>>XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-conta (334 aa)
initn: 574 init1: 297 opt: 328 Z-score: 250.6 bits: 56.0 E(85289): 3.2e-07
Smith-Waterman score: 367; 24.0% identity (58.6% similar) in 304 aa overlap (106-404:42-331)
80 90 100 110 120 130
pF1KB3 PDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGGCDGAVRV
: :: :... :.:.. ::... : ...
XP_005 AARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKI
20 30 40 50 60 70
140 150 160 170 180 190
pF1KB3 WDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTAHY
: . . : . ::. : . :: :.. : ....:.... .:: .: .:
XP_005 WGAYDGKFEKTISGHKLGISDVAWSSDSN--LLVSASDDKTLKIWDVSSGKCLKTLKGHS
80 90 100 110 120
200 210 220 230 240 250
pF1KB3 SAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEPVSQLGV
. : :. ... ..:.. :. :::... . .:.:. .::: .
XP_005 NYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHS----------DPVSAVHF
130 140 150 160 170
260 270 280 290 300 310
pF1KB3 KSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGRELTHCTLAHTAGVVLTATADHN
. : ..... .: :.:..:::::. : . .: .. .. .. .:.:: :..
XP_005 NRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNP--PVSFVKFSPNGKYILAATLDNT
180 190 200 210 220 230
320 330 340 350 360 370
pF1KB3 LLLYEARSLRLQKQFAGYSEEVLDV--RFLGPEDSHVVVASNSPCLKVFELQTSA-CQIL
: :.. . . : ..:...: . : . .: .:.. . ...:::. : :
XP_005 LKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKL
240 250 260 270 280 290
380 390 400 410 420 430
pF1KB3 HGHTDIVLALDVFRKGWLFASCA--KDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCS
.::::.:.. ..:: : .:.....:.
XP_005 QGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC
300 310 320 330
440 450 460 470 480 490
pF1KB3 RLKESFLVTGSQDCTVKLWPLPKALLPKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPN
>>NP_438172 (OMIM: 609012) WD repeat-containing protein (334 aa)
initn: 574 init1: 297 opt: 328 Z-score: 250.6 bits: 56.0 E(85289): 3.2e-07
Smith-Waterman score: 367; 24.0% identity (58.6% similar) in 304 aa overlap (106-404:42-331)
80 90 100 110 120 130
pF1KB3 PDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGGCDGAVRV
: :: :... :.:.. ::... : ...
NP_438 AARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKI
20 30 40 50 60 70
140 150 160 170 180 190
pF1KB3 WDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTAHY
: . . : . ::. : . :: :.. : ....:.... .:: .: .:
NP_438 WGAYDGKFEKTISGHKLGISDVAWSSDSN--LLVSASDDKTLKIWDVSSGKCLKTLKGHS
80 90 100 110 120
200 210 220 230 240 250
pF1KB3 SAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEPVSQLGV
. : :. ... ..:.. :. :::... . .:.:. .::: .
NP_438 NYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHS----------DPVSAVHF
130 140 150 160 170
260 270 280 290 300 310
pF1KB3 KSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGRELTHCTLAHTAGVVLTATADHN
. : ..... .: :.:..:::::. : . .: .. .. .. .:.:: :..
NP_438 NRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNP--PVSFVKFSPNGKYILAATLDNT
180 190 200 210 220 230
320 330 340 350 360 370
pF1KB3 LLLYEARSLRLQKQFAGYSEEVLDV--RFLGPEDSHVVVASNSPCLKVFELQTSA-CQIL
: :.. . . : ..:...: . : . .: .:.. . ...:::. : :
NP_438 LKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKL
240 250 260 270 280 290
380 390 400 410 420 430
pF1KB3 HGHTDIVLALDVFRKGWLFASCA--KDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCS
.::::.:.. ..:: : .:.....:.
NP_438 QGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC
300 310 320 330
440 450 460 470 480 490
pF1KB3 RLKESFLVTGSQDCTVKLWPLPKALLPKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPN
>>NP_942593 (OMIM: 610767,611081) autophagy-related prot (444 aa)
initn: 317 init1: 168 opt: 323 Z-score: 245.9 bits: 55.5 E(85289): 5.9e-07
Smith-Waterman score: 323; 26.9% identity (63.7% similar) in 223 aa overlap (445-658:124-332)
420 430 440 450 460 470
pF1KB3 AQGSGHTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLPKNTAPDNGPILLQAQTT
.:. .:.:. . .: : .: ... .:
NP_942 DDIEVIVDETSDHTEETSPVRAISRAATRRSVSSFPVPQDNV--DTHPGSGK-EVRVPAT
100 110 120 130 140 150
480 490 500 510 520
pF1KB3 QRC----HDKDINSVAIAPNDKLLATGSQDRTAKLWAL--PQCQLLGVFSGHRRGLWCVQ
: :: ..:.: ..:...:::::..:: .::: . .:.. : .:: :. ..
NP_942 ALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIE
160 170 180 190 200 210
530 540 550 560 570 580
pF1KB3 FSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVK
:. . : .:: : . ..:...:. .:. ::...::.. :. .....:.. : .:
NP_942 FDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLK
220 230 240 250 260 270
590 600 610 620 630 640
pF1KB3 LWTIKNNECVRTLDAHEDKVWGLHCSRL---DDHALTGASDSRVILWKDVTEAEQAEEQA
:: .... :..:. : : :. . .. ...: :... .: :. ..: .
NP_942 LWDLRSKVCIKTVFA------GSSCNDIVCTEQCVMSGHFDKKIRFW-DI----RSESIV
280 290 300 310
650 660 670 680 690 700
pF1KB3 RQEEQVVRQQELDNLLHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPEACEKLEATMLR
:. : . . ::
NP_942 REMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVF
320 330 340 350 360 370
>>XP_005246143 (OMIM: 610767,611081) PREDICTED: autophag (463 aa)
initn: 317 init1: 168 opt: 323 Z-score: 245.7 bits: 55.6 E(85289): 6e-07
Smith-Waterman score: 323; 26.9% identity (63.7% similar) in 223 aa overlap (445-658:143-351)
420 430 440 450 460 470
pF1KB3 AQGSGHTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLPKNTAPDNGPILLQAQTT
.:. .:.:. . .: : .: ... .:
XP_005 VRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSFPVPQDNV--DTHPGSGK-EVRVPAT
120 130 140 150 160
480 490 500 510 520
pF1KB3 QRC----HDKDINSVAIAPNDKLLATGSQDRTAKLWAL--PQCQLLGVFSGHRRGLWCVQ
: :: ..:.: ..:...:::::..:: .::: . .:.. : .:: :. ..
XP_005 ALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIE
170 180 190 200 210 220
530 540 550 560 570 580
pF1KB3 FSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVK
:. . : .:: : . ..:...:. .:. ::...::.. :. .....:.. : .:
XP_005 FDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLK
230 240 250 260 270 280
590 600 610 620 630 640
pF1KB3 LWTIKNNECVRTLDAHEDKVWGLHCSRL---DDHALTGASDSRVILWKDVTEAEQAEEQA
:: .... :..:. : : :. . .. ...: :... .: :. ..: .
XP_005 LWDLRSKVCIKTVFA------GSSCNDIVCTEQCVMSGHFDKKIRFW-DI----RSESIV
290 300 310 320 330
650 660 670 680 690 700
pF1KB3 RQEEQVVRQQELDNLLHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPEACEKLEATMLR
:. : . . ::
XP_005 REMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVF
340 350 360 370 380 390
>>XP_005246141 (OMIM: 610767,611081) PREDICTED: autophag (480 aa)
initn: 317 init1: 168 opt: 323 Z-score: 245.6 bits: 55.6 E(85289): 6.1e-07
Smith-Waterman score: 323; 26.9% identity (63.7% similar) in 223 aa overlap (445-658:160-368)
420 430 440 450 460 470
pF1KB3 AQGSGHTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLPKNTAPDNGPILLQAQTT
.:. .:.:. . .: : .: ... .:
XP_005 GLLDSITNIFGLSESPLLGHHSSSDAARRRSVSSFPVPQDNV--DTHPGSGK-EVRVPAT
130 140 150 160 170 180
480 490 500 510 520
pF1KB3 QRC----HDKDINSVAIAPNDKLLATGSQDRTAKLWAL--PQCQLLGVFSGHRRGLWCVQ
: :: ..:.: ..:...:::::..:: .::: . .:.. : .:: :. ..
XP_005 ALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIE
190 200 210 220 230 240
530 540 550 560 570 580
pF1KB3 FSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVK
:. . : .:: : . ..:...:. .:. ::...::.. :. .....:.. : .:
XP_005 FDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLK
250 260 270 280 290 300
590 600 610 620 630 640
pF1KB3 LWTIKNNECVRTLDAHEDKVWGLHCSRL---DDHALTGASDSRVILWKDVTEAEQAEEQA
:: .... :..:. : : :. . .. ...: :... .: :. ..: .
XP_005 LWDLRSKVCIKTVFA------GSSCNDIVCTEQCVMSGHFDKKIRFW-DI----RSESIV
310 320 330 340 350
650 660 670 680 690 700
pF1KB3 RQEEQVVRQQELDNLLHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPEACEKLEATMLR
:. : . . ::
XP_005 REMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVF
360 370 380 390 400 410
>>NP_001177196 (OMIM: 610767,611081) autophagy-related p (491 aa)
initn: 317 init1: 168 opt: 323 Z-score: 245.5 bits: 55.6 E(85289): 6.2e-07
Smith-Waterman score: 323; 26.9% identity (63.7% similar) in 223 aa overlap (445-658:171-379)
420 430 440 450 460 470
pF1KB3 AQGSGHTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLPKNTAPDNGPILLQAQTT
.:. .:.:. . .: : .: ... .:
NP_001 VRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSFPVPQDNV--DTHPGSGK-EVRVPAT
150 160 170 180 190
480 490 500 510 520
pF1KB3 QRC----HDKDINSVAIAPNDKLLATGSQDRTAKLWAL--PQCQLLGVFSGHRRGLWCVQ
: :: ..:.: ..:...:::::..:: .::: . .:.. : .:: :. ..
NP_001 ALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIE
200 210 220 230 240 250
530 540 550 560 570 580
pF1KB3 FSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVK
:. . : .:: : . ..:...:. .:. ::...::.. :. .....:.. : .:
NP_001 FDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLK
260 270 280 290 300 310
590 600 610 620 630 640
pF1KB3 LWTIKNNECVRTLDAHEDKVWGLHCSRL---DDHALTGASDSRVILWKDVTEAEQAEEQA
:: .... :..:. : : :. . .. ...: :... .: :. ..: .
NP_001 LWDLRSKVCIKTVFA------GSSCNDIVCTEQCVMSGHFDKKIRFW-DI----RSESIV
320 330 340 350 360
650 660 670 680 690 700
pF1KB3 RQEEQVVRQQELDNLLHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPEACEKLEATMLR
:. : . . ::
NP_001 REMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVF
370 380 390 400 410 420
>>NP_001177195 (OMIM: 610767,611081) autophagy-related p (523 aa)
initn: 317 init1: 168 opt: 323 Z-score: 245.2 bits: 55.6 E(85289): 6.4e-07
Smith-Waterman score: 323; 26.9% identity (63.7% similar) in 223 aa overlap (445-658:203-411)
420 430 440 450 460 470
pF1KB3 AQGSGHTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLPKNTAPDNGPILLQAQTT
.:. .:.:. . .: : .: ... .:
NP_001 VRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSFPVPQDNV--DTHPGSGK-EVRVPAT
180 190 200 210 220
480 490 500 510 520
pF1KB3 QRC----HDKDINSVAIAPNDKLLATGSQDRTAKLWAL--PQCQLLGVFSGHRRGLWCVQ
: :: ..:.: ..:...:::::..:: .::: . .:.. : .:: :. ..
NP_001 ALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIE
230 240 250 260 270 280
530 540 550 560 570 580
pF1KB3 FSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVK
:. . : .:: : . ..:...:. .:. ::...::.. :. .....:.. : .:
NP_001 FDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLK
290 300 310 320 330 340
590 600 610 620 630 640
pF1KB3 LWTIKNNECVRTLDAHEDKVWGLHCSRL---DDHALTGASDSRVILWKDVTEAEQAEEQA
:: .... :..:. : : :. . .. ...: :... .: :. ..: .
NP_001 LWDLRSKVCIKTVFA------GSSCNDIVCTEQCVMSGHFDKKIRFW-DI----RSESIV
350 360 370 380 390
650 660 670 680 690 700
pF1KB3 RQEEQVVRQQELDNLLHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPEACEKLEATMLR
:. : . . ::
NP_001 REMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVF
400 410 420 430 440 450
808 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 14:07:59 2016 done: Thu Nov 3 14:08:01 2016
Total Scan time: 13.310 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]