Result of FASTA (omim) for
pF1KB3668
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3668, 261 aa
1>>>pF1KB3668 261 - 261 aa - 261 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.5523+/-0.000468; mu= 6.0914+/- 0.029
mean_var=233.1294+/-48.870, 0's: 0 Z-trim(116.5): 40 B-trim: 0 in 0/51
Lambda= 0.083999
statistics sampled from 27732 (27757) to 27732 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.687), E-opt: 0.2 (0.325), width: 16
Scan time: 6.180
The best scores are: opt bits E(85289)
NP_056251 (OMIM: 607680) RING finger and CHY zinc ( 261) 1932 246.8 2.9e-65
NP_001265467 (OMIM: 607680) RING finger and CHY zi ( 239) 1720 221.1 1.5e-57
NP_001265465 (OMIM: 607680) RING finger and CHY zi ( 221) 1410 183.5 2.9e-46
NP_001009922 (OMIM: 607680) RING finger and CHY zi ( 252) 1285 168.4 1.2e-41
XP_011530140 (OMIM: 607680) PREDICTED: RING finger ( 134) 961 128.8 5.1e-30
XP_011530141 (OMIM: 607680) PREDICTED: RING finger ( 134) 961 128.8 5.1e-30
NP_001265468 (OMIM: 607680) RING finger and CHY zi ( 134) 961 128.8 5.1e-30
NP_001265466 (OMIM: 607680) RING finger and CHY zi ( 212) 763 105.0 1.1e-22
>>NP_056251 (OMIM: 607680) RING finger and CHY zinc fing (261 aa)
initn: 1932 init1: 1932 opt: 1932 Z-score: 1292.6 bits: 246.8 E(85289): 2.9e-65
Smith-Waterman score: 1932; 99.6% identity (100.0% similar) in 261 aa overlap (1-261:1-261)
10 20 30 40 50 60
pF1KB3 MAATAREDGASGQERGQRGCEHYDRGCLLKAPCCDKLYTCRLCHDNNEDHQLDRFKVKEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MAATAREDGASGQERGQRGCEHYDRGCLLKAPCCDKLYTCRLCHDNNEDHQLDRFKVKEV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 QCINCEKIQHAQQTCEECSTLFGEYYCDICHLFDKDKKQYHCENCGICRIGPKEDFFHCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QCINCEKIQHAQQTCEECSTLFGEYYCDICHLFDKDKKQYHCENCGICRIGPKEDFFHCL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 KCNLCLAMNLQGRHKCIENVSRQNCPICLEDIHTSRVVAHVLPCGHLLHRTCYEEMLKEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KCNLCLAMNLQGRHKCIENVSRQNCPICLEDIHTSRVVAHVLPCGHLLHRTCYEEMLKEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 YRCPLCMHSALDMTRYWRQLDDEVAQTPMPSEYQNMTVDFLCNDCNGRSTVQFHILGMKC
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
NP_056 YRCPLCMHSALDMTRYWRQLDDEVAQTPMPSEYQNMTVDILCNDCNGRSTVQFHILGMKC
190 200 210 220 230 240
250 260
pF1KB3 KICESYNTAQAGGRRISLDQQ
:::::::::::::::::::::
NP_056 KICESYNTAQAGGRRISLDQQ
250 260
>>NP_001265467 (OMIM: 607680) RING finger and CHY zinc f (239 aa)
initn: 1720 init1: 1720 opt: 1720 Z-score: 1154.2 bits: 221.1 E(85289): 1.5e-57
Smith-Waterman score: 1720; 99.1% identity (100.0% similar) in 232 aa overlap (30-261:8-239)
10 20 30 40 50 60
pF1KB3 MAATAREDGASGQERGQRGCEHYDRGCLLKAPCCDKLYTCRLCHDNNEDHQLDRFKVKEV
.::::::::::::::::::::::::::::::
NP_001 MAPAVKSEAPCCDKLYTCRLCHDNNEDHQLDRFKVKEV
10 20 30
70 80 90 100 110 120
pF1KB3 QCINCEKIQHAQQTCEECSTLFGEYYCDICHLFDKDKKQYHCENCGICRIGPKEDFFHCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QCINCEKIQHAQQTCEECSTLFGEYYCDICHLFDKDKKQYHCENCGICRIGPKEDFFHCL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB3 KCNLCLAMNLQGRHKCIENVSRQNCPICLEDIHTSRVVAHVLPCGHLLHRTCYEEMLKEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCNLCLAMNLQGRHKCIENVSRQNCPICLEDIHTSRVVAHVLPCGHLLHRTCYEEMLKEG
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB3 YRCPLCMHSALDMTRYWRQLDDEVAQTPMPSEYQNMTVDFLCNDCNGRSTVQFHILGMKC
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
NP_001 YRCPLCMHSALDMTRYWRQLDDEVAQTPMPSEYQNMTVDILCNDCNGRSTVQFHILGMKC
160 170 180 190 200 210
250 260
pF1KB3 KICESYNTAQAGGRRISLDQQ
:::::::::::::::::::::
NP_001 KICESYNTAQAGGRRISLDQQ
220 230
>>NP_001265465 (OMIM: 607680) RING finger and CHY zinc f (221 aa)
initn: 1410 init1: 1410 opt: 1410 Z-score: 951.5 bits: 183.5 E(85289): 2.9e-46
Smith-Waterman score: 1533; 84.3% identity (84.7% similar) in 261 aa overlap (1-261:1-221)
10 20 30 40 50 60
pF1KB3 MAATAREDGASGQERGQRGCEHYDRGCLLKAPCCDKLYTCRLCHDNNEDHQLDRFKVKEV
:::::::::::::::::::::::::::::::
NP_001 MAATAREDGASGQERGQRGCEHYDRGCLLKA-----------------------------
10 20 30
70 80 90 100 110 120
pF1KB3 QCINCEKIQHAQQTCEECSTLFGEYYCDICHLFDKDKKQYHCENCGICRIGPKEDFFHCL
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -----------QQTCEECSTLFGEYYCDICHLFDKDKKQYHCENCGICRIGPKEDFFHCL
40 50 60 70 80
130 140 150 160 170 180
pF1KB3 KCNLCLAMNLQGRHKCIENVSRQNCPICLEDIHTSRVVAHVLPCGHLLHRTCYEEMLKEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCNLCLAMNLQGRHKCIENVSRQNCPICLEDIHTSRVVAHVLPCGHLLHRTCYEEMLKEG
90 100 110 120 130 140
190 200 210 220 230 240
pF1KB3 YRCPLCMHSALDMTRYWRQLDDEVAQTPMPSEYQNMTVDFLCNDCNGRSTVQFHILGMKC
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
NP_001 YRCPLCMHSALDMTRYWRQLDDEVAQTPMPSEYQNMTVDILCNDCNGRSTVQFHILGMKC
150 160 170 180 190 200
250 260
pF1KB3 KICESYNTAQAGGRRISLDQQ
:::::::::::::::::::::
NP_001 KICESYNTAQAGGRRISLDQQ
210 220
>>NP_001009922 (OMIM: 607680) RING finger and CHY zinc f (252 aa)
initn: 1285 init1: 1285 opt: 1285 Z-score: 869.0 bits: 168.4 E(85289): 1.2e-41
Smith-Waterman score: 1842; 96.2% identity (96.6% similar) in 261 aa overlap (1-261:1-252)
10 20 30 40 50 60
pF1KB3 MAATAREDGASGQERGQRGCEHYDRGCLLKAPCCDKLYTCRLCHDNNEDHQLDRFKVKEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAATAREDGASGQERGQRGCEHYDRGCLLKAPCCDKLYTCRLCHDNNEDHQLDRFKVKEV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 QCINCEKIQHAQQTCEECSTLFGEYYCDICHLFDKDKKQYHCENCGICRIGPKEDFFHCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QCINCEKIQHAQQTCEECSTLFGEYYCDICHLFDKDKKQYHCENCGICRIGPKEDFFHCL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 KCNLCLAMNLQGRHKCIENVSRQNCPICLEDIHTSRVVAHVLPCGHLLHRTCYEEMLKEG
:::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_001 KCNLCLAMNLQGRHKCIENVSRQNCPICLEDIHTSRVVAHVLPCGHLLHR---------G
130 140 150 160 170
190 200 210 220 230 240
pF1KB3 YRCPLCMHSALDMTRYWRQLDDEVAQTPMPSEYQNMTVDFLCNDCNGRSTVQFHILGMKC
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
NP_001 YRCPLCMHSALDMTRYWRQLDDEVAQTPMPSEYQNMTVDILCNDCNGRSTVQFHILGMKC
180 190 200 210 220 230
250 260
pF1KB3 KICESYNTAQAGGRRISLDQQ
:::::::::::::::::::::
NP_001 KICESYNTAQAGGRRISLDQQ
240 250
>>XP_011530140 (OMIM: 607680) PREDICTED: RING finger and (134 aa)
initn: 961 init1: 961 opt: 961 Z-score: 659.9 bits: 128.8 E(85289): 5.1e-30
Smith-Waterman score: 961; 99.3% identity (100.0% similar) in 134 aa overlap (128-261:1-134)
100 110 120 130 140 150
pF1KB3 KQYHCENCGICRIGPKEDFFHCLKCNLCLAMNLQGRHKCIENVSRQNCPICLEDIHTSRV
::::::::::::::::::::::::::::::
XP_011 MNLQGRHKCIENVSRQNCPICLEDIHTSRV
10 20 30
160 170 180 190 200 210
pF1KB3 VAHVLPCGHLLHRTCYEEMLKEGYRCPLCMHSALDMTRYWRQLDDEVAQTPMPSEYQNMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAHVLPCGHLLHRTCYEEMLKEGYRCPLCMHSALDMTRYWRQLDDEVAQTPMPSEYQNMT
40 50 60 70 80 90
220 230 240 250 260
pF1KB3 VDFLCNDCNGRSTVQFHILGMKCKICESYNTAQAGGRRISLDQQ
::.:::::::::::::::::::::::::::::::::::::::::
XP_011 VDILCNDCNGRSTVQFHILGMKCKICESYNTAQAGGRRISLDQQ
100 110 120 130
>>XP_011530141 (OMIM: 607680) PREDICTED: RING finger and (134 aa)
initn: 961 init1: 961 opt: 961 Z-score: 659.9 bits: 128.8 E(85289): 5.1e-30
Smith-Waterman score: 961; 99.3% identity (100.0% similar) in 134 aa overlap (128-261:1-134)
100 110 120 130 140 150
pF1KB3 KQYHCENCGICRIGPKEDFFHCLKCNLCLAMNLQGRHKCIENVSRQNCPICLEDIHTSRV
::::::::::::::::::::::::::::::
XP_011 MNLQGRHKCIENVSRQNCPICLEDIHTSRV
10 20 30
160 170 180 190 200 210
pF1KB3 VAHVLPCGHLLHRTCYEEMLKEGYRCPLCMHSALDMTRYWRQLDDEVAQTPMPSEYQNMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAHVLPCGHLLHRTCYEEMLKEGYRCPLCMHSALDMTRYWRQLDDEVAQTPMPSEYQNMT
40 50 60 70 80 90
220 230 240 250 260
pF1KB3 VDFLCNDCNGRSTVQFHILGMKCKICESYNTAQAGGRRISLDQQ
::.:::::::::::::::::::::::::::::::::::::::::
XP_011 VDILCNDCNGRSTVQFHILGMKCKICESYNTAQAGGRRISLDQQ
100 110 120 130
>>NP_001265468 (OMIM: 607680) RING finger and CHY zinc f (134 aa)
initn: 961 init1: 961 opt: 961 Z-score: 659.9 bits: 128.8 E(85289): 5.1e-30
Smith-Waterman score: 961; 99.3% identity (100.0% similar) in 134 aa overlap (128-261:1-134)
100 110 120 130 140 150
pF1KB3 KQYHCENCGICRIGPKEDFFHCLKCNLCLAMNLQGRHKCIENVSRQNCPICLEDIHTSRV
::::::::::::::::::::::::::::::
NP_001 MNLQGRHKCIENVSRQNCPICLEDIHTSRV
10 20 30
160 170 180 190 200 210
pF1KB3 VAHVLPCGHLLHRTCYEEMLKEGYRCPLCMHSALDMTRYWRQLDDEVAQTPMPSEYQNMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAHVLPCGHLLHRTCYEEMLKEGYRCPLCMHSALDMTRYWRQLDDEVAQTPMPSEYQNMT
40 50 60 70 80 90
220 230 240 250 260
pF1KB3 VDFLCNDCNGRSTVQFHILGMKCKICESYNTAQAGGRRISLDQQ
::.:::::::::::::::::::::::::::::::::::::::::
NP_001 VDILCNDCNGRSTVQFHILGMKCKICESYNTAQAGGRRISLDQQ
100 110 120 130
>>NP_001265466 (OMIM: 607680) RING finger and CHY zinc f (212 aa)
initn: 849 init1: 763 opt: 763 Z-score: 528.0 bits: 105.0 E(85289): 1.1e-22
Smith-Waterman score: 1443; 80.8% identity (81.2% similar) in 261 aa overlap (1-261:1-212)
10 20 30 40 50 60
pF1KB3 MAATAREDGASGQERGQRGCEHYDRGCLLKAPCCDKLYTCRLCHDNNEDHQLDRFKVKEV
:::::::::::::::::::::::::::::::
NP_001 MAATAREDGASGQERGQRGCEHYDRGCLLKA-----------------------------
10 20 30
70 80 90 100 110 120
pF1KB3 QCINCEKIQHAQQTCEECSTLFGEYYCDICHLFDKDKKQYHCENCGICRIGPKEDFFHCL
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -----------QQTCEECSTLFGEYYCDICHLFDKDKKQYHCENCGICRIGPKEDFFHCL
40 50 60 70 80
130 140 150 160 170 180
pF1KB3 KCNLCLAMNLQGRHKCIENVSRQNCPICLEDIHTSRVVAHVLPCGHLLHRTCYEEMLKEG
:::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_001 KCNLCLAMNLQGRHKCIENVSRQNCPICLEDIHTSRVVAHVLPCGHLLHR---------G
90 100 110 120 130
190 200 210 220 230 240
pF1KB3 YRCPLCMHSALDMTRYWRQLDDEVAQTPMPSEYQNMTVDFLCNDCNGRSTVQFHILGMKC
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
NP_001 YRCPLCMHSALDMTRYWRQLDDEVAQTPMPSEYQNMTVDILCNDCNGRSTVQFHILGMKC
140 150 160 170 180 190
250 260
pF1KB3 KICESYNTAQAGGRRISLDQQ
:::::::::::::::::::::
NP_001 KICESYNTAQAGGRRISLDQQ
200 210
261 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:58:05 2016 done: Fri Nov 4 20:58:06 2016
Total Scan time: 6.180 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]