Result of FASTA (omim) for
pF1KB3652
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3652, 768 aa
1>>>pF1KB3652 768 - 768 aa - 768 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.2939+/-0.000419; mu= -6.9003+/- 0.026
mean_var=342.4322+/-69.114, 0's: 0 Z-trim(121.8): 33 B-trim: 57 in 1/59
Lambda= 0.069309
statistics sampled from 38789 (38823) to 38789 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.752), E-opt: 0.2 (0.455), width: 16
Scan time: 14.800
The best scores are: opt bits E(85289)
NP_054908 (OMIM: 102680,145500) alpha-adducin isof ( 768) 5124 526.7 1.4e-148
XP_016863193 (OMIM: 102680,145500) PREDICTED: alph ( 768) 5124 526.7 1.4e-148
XP_016863194 (OMIM: 102680,145500) PREDICTED: alph ( 768) 4430 457.3 1.1e-127
XP_005247992 (OMIM: 102680,145500) PREDICTED: alph ( 768) 4430 457.3 1.1e-127
NP_789771 (OMIM: 102680,145500) alpha-adducin isof ( 662) 4336 447.8 6.7e-125
XP_016863192 (OMIM: 102680,145500) PREDICTED: alph ( 799) 3792 393.5 1.8e-108
XP_005247990 (OMIM: 102680,145500) PREDICTED: alph ( 799) 3792 393.5 1.8e-108
XP_005247991 (OMIM: 102680,145500) PREDICTED: alph ( 799) 3792 393.5 1.8e-108
XP_005247993 (OMIM: 102680,145500) PREDICTED: alph ( 693) 3777 392.0 4.6e-108
XP_016863197 (OMIM: 102680,145500) PREDICTED: alph ( 662) 3642 378.4 5.2e-104
NP_001273574 (OMIM: 102680,145500) alpha-adducin i ( 662) 3642 378.4 5.2e-104
XP_005247994 (OMIM: 102680,145500) PREDICTED: alph ( 662) 3642 378.4 5.2e-104
XP_016863199 (OMIM: 102680,145500) PREDICTED: alph ( 631) 3135 327.7 9.1e-89
XP_016863198 (OMIM: 102680,145500) PREDICTED: alph ( 631) 3135 327.7 9.1e-89
NP_054909 (OMIM: 102680,145500) alpha-adducin isof ( 631) 3135 327.7 9.1e-89
XP_016863196 (OMIM: 102680,145500) PREDICTED: alph ( 737) 3135 327.8 1e-88
XP_016863195 (OMIM: 102680,145500) PREDICTED: alph ( 737) 3135 327.8 1e-88
NP_001110 (OMIM: 102680,145500) alpha-adducin isof ( 737) 3135 327.8 1e-88
NP_063968 (OMIM: 601568,617008) gamma-adducin isof ( 674) 1882 202.5 5e-51
NP_001112 (OMIM: 601568,617008) gamma-adducin isof ( 674) 1882 202.5 5e-51
NP_001307520 (OMIM: 601568,617008) gamma-adducin i ( 706) 1882 202.5 5.2e-51
NP_001307522 (OMIM: 601568,617008) gamma-adducin i ( 706) 1882 202.5 5.2e-51
NP_058432 (OMIM: 601568,617008) gamma-adducin isof ( 706) 1882 202.5 5.2e-51
NP_001307521 (OMIM: 601568,617008) gamma-adducin i ( 706) 1882 202.5 5.2e-51
NP_059516 (OMIM: 102681) beta-adducin isoform b [H ( 559) 1620 176.2 3.3e-43
NP_001171984 (OMIM: 102681) beta-adducin isoform f ( 575) 1620 176.2 3.4e-43
NP_059522 (OMIM: 102681) beta-adducin isoform e [H ( 643) 1620 176.3 3.7e-43
XP_011530804 (OMIM: 102681) PREDICTED: beta-adduci ( 726) 1620 176.3 4.1e-43
NP_001608 (OMIM: 102681) beta-adducin isoform a [H ( 726) 1620 176.3 4.1e-43
NP_001171983 (OMIM: 102681) beta-adducin isoform a ( 726) 1620 176.3 4.1e-43
NP_001307523 (OMIM: 601568,617008) gamma-adducin i ( 628) 1472 161.4 1e-38
>>NP_054908 (OMIM: 102680,145500) alpha-adducin isoform (768 aa)
initn: 5124 init1: 5124 opt: 5124 Z-score: 2788.3 bits: 526.7 E(85289): 1.4e-148
Smith-Waterman score: 5124; 100.0% identity (100.0% similar) in 768 aa overlap (1-768:1-768)
10 20 30 40 50 60
pF1KB3 MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 DDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 DDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA
670 680 690 700 710 720
730 740 750 760
pF1KB3 EEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKKSDS
::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 EEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKKSDS
730 740 750 760
>>XP_016863193 (OMIM: 102680,145500) PREDICTED: alpha-ad (768 aa)
initn: 5124 init1: 5124 opt: 5124 Z-score: 2788.3 bits: 526.7 E(85289): 1.4e-148
Smith-Waterman score: 5124; 100.0% identity (100.0% similar) in 768 aa overlap (1-768:1-768)
10 20 30 40 50 60
pF1KB3 MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 DDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA
670 680 690 700 710 720
730 740 750 760
pF1KB3 EEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKKSDS
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKKSDS
730 740 750 760
>>XP_016863194 (OMIM: 102680,145500) PREDICTED: alpha-ad (768 aa)
initn: 4387 init1: 4387 opt: 4430 Z-score: 2413.3 bits: 457.3 E(85289): 1.1e-127
Smith-Waterman score: 4758; 92.2% identity (92.2% similar) in 799 aa overlap (1-768:1-768)
10 20 30 40 50 60
pF1KB3 MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTK---------
430 440 450 460 470
490 500 510 520 530 540
pF1KB3 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
::::::::::::::::::::::::::::::::::::::
XP_016 ----------------------WTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
480 490 500
550 560
pF1KB3 NLQDIKTAGPQSQVLCGVVMDRSLVQ-------------------------------GEL
:::::::::::::::::::::::::: :::
XP_016 NLQDIKTAGPQSQVLCGVVMDRSLVQDAPLSDCTETIEGLELTEQTFSPAKSLSFRKGEL
510 520 530 540 550 560
570 580 590 600 610 620
pF1KB3 VTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKE
570 580 590 600 610 620
630 640 650 660 670 680
pF1KB3 KSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPML
630 640 650 660 670 680
690 700 710 720 730 740
pF1KB3 EKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKK
690 700 710 720 730 740
750 760
pF1KB3 KKKFRTPSFLKKSKKKSDS
:::::::::::::::::::
XP_016 KKKFRTPSFLKKSKKKSDS
750 760
>>XP_005247992 (OMIM: 102680,145500) PREDICTED: alpha-ad (768 aa)
initn: 4387 init1: 4387 opt: 4430 Z-score: 2413.3 bits: 457.3 E(85289): 1.1e-127
Smith-Waterman score: 4758; 92.2% identity (92.2% similar) in 799 aa overlap (1-768:1-768)
10 20 30 40 50 60
pF1KB3 MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTK---------
430 440 450 460 470
490 500 510 520 530 540
pF1KB3 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
::::::::::::::::::::::::::::::::::::::
XP_005 ----------------------WTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
480 490 500
550 560
pF1KB3 NLQDIKTAGPQSQVLCGVVMDRSLVQ-------------------------------GEL
:::::::::::::::::::::::::: :::
XP_005 NLQDIKTAGPQSQVLCGVVMDRSLVQDAPLSDCTETIEGLELTEQTFSPAKSLSFRKGEL
510 520 530 540 550 560
570 580 590 600 610 620
pF1KB3 VTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKE
570 580 590 600 610 620
630 640 650 660 670 680
pF1KB3 KSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPML
630 640 650 660 670 680
690 700 710 720 730 740
pF1KB3 EKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKK
690 700 710 720 730 740
750 760
pF1KB3 KKKFRTPSFLKKSKKKSDS
:::::::::::::::::::
XP_005 KKKFRTPSFLKKSKKKSDS
750 760
>>NP_789771 (OMIM: 102680,145500) alpha-adducin isoform (662 aa)
initn: 4336 init1: 4336 opt: 4336 Z-score: 2363.4 bits: 447.8 E(85289): 6.7e-125
Smith-Waterman score: 4336; 100.0% identity (100.0% similar) in 651 aa overlap (1-651:1-651)
10 20 30 40 50 60
pF1KB3 MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 NLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTG
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEGDGCAREYL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 DDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA
NP_789 LP
>>XP_016863192 (OMIM: 102680,145500) PREDICTED: alpha-ad (799 aa)
initn: 3855 init1: 3777 opt: 3792 Z-score: 2068.3 bits: 393.5 E(85289): 1.8e-108
Smith-Waterman score: 5052; 96.1% identity (96.1% similar) in 799 aa overlap (1-768:1-799)
10 20 30 40 50 60
pF1KB3 MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
490 500 510 520 530 540
550 560
pF1KB3 NLQDIKTAGPQSQVLCGVVMDRSLVQ-------------------------------GEL
:::::::::::::::::::::::::: :::
XP_016 NLQDIKTAGPQSQVLCGVVMDRSLVQDAPLSDCTETIEGLELTEQTFSPAKSLSFRKGEL
550 560 570 580 590 600
570 580 590 600 610 620
pF1KB3 VTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKE
610 620 630 640 650 660
630 640 650 660 670 680
pF1KB3 KSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPML
670 680 690 700 710 720
690 700 710 720 730 740
pF1KB3 EKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKK
730 740 750 760 770 780
750 760
pF1KB3 KKKFRTPSFLKKSKKKSDS
:::::::::::::::::::
XP_016 KKKFRTPSFLKKSKKKSDS
790
>>XP_005247990 (OMIM: 102680,145500) PREDICTED: alpha-ad (799 aa)
initn: 3855 init1: 3777 opt: 3792 Z-score: 2068.3 bits: 393.5 E(85289): 1.8e-108
Smith-Waterman score: 5052; 96.1% identity (96.1% similar) in 799 aa overlap (1-768:1-799)
10 20 30 40 50 60
pF1KB3 MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
490 500 510 520 530 540
550 560
pF1KB3 NLQDIKTAGPQSQVLCGVVMDRSLVQ-------------------------------GEL
:::::::::::::::::::::::::: :::
XP_005 NLQDIKTAGPQSQVLCGVVMDRSLVQDAPLSDCTETIEGLELTEQTFSPAKSLSFRKGEL
550 560 570 580 590 600
570 580 590 600 610 620
pF1KB3 VTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKE
610 620 630 640 650 660
630 640 650 660 670 680
pF1KB3 KSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPML
670 680 690 700 710 720
690 700 710 720 730 740
pF1KB3 EKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKK
730 740 750 760 770 780
750 760
pF1KB3 KKKFRTPSFLKKSKKKSDS
:::::::::::::::::::
XP_005 KKKFRTPSFLKKSKKKSDS
790
>>XP_005247991 (OMIM: 102680,145500) PREDICTED: alpha-ad (799 aa)
initn: 3855 init1: 3777 opt: 3792 Z-score: 2068.3 bits: 393.5 E(85289): 1.8e-108
Smith-Waterman score: 5052; 96.1% identity (96.1% similar) in 799 aa overlap (1-768:1-799)
10 20 30 40 50 60
pF1KB3 MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
490 500 510 520 530 540
550 560
pF1KB3 NLQDIKTAGPQSQVLCGVVMDRSLVQ-------------------------------GEL
:::::::::::::::::::::::::: :::
XP_005 NLQDIKTAGPQSQVLCGVVMDRSLVQDAPLSDCTETIEGLELTEQTFSPAKSLSFRKGEL
550 560 570 580 590 600
570 580 590 600 610 620
pF1KB3 VTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKE
610 620 630 640 650 660
630 640 650 660 670 680
pF1KB3 KSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPML
670 680 690 700 710 720
690 700 710 720 730 740
pF1KB3 EKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKK
730 740 750 760 770 780
750 760
pF1KB3 KKKFRTPSFLKKSKKKSDS
:::::::::::::::::::
XP_005 KKKFRTPSFLKKSKKKSDS
790
>>XP_005247993 (OMIM: 102680,145500) PREDICTED: alpha-ad (693 aa)
initn: 3777 init1: 3777 opt: 3777 Z-score: 2061.0 bits: 392.0 E(85289): 4.6e-108
Smith-Waterman score: 4264; 95.5% identity (95.5% similar) in 682 aa overlap (1-651:1-682)
10 20 30 40 50 60
pF1KB3 MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
490 500 510 520 530 540
550 560
pF1KB3 NLQDIKTAGPQSQVLCGVVMDRSLVQ-------------------------------GEL
:::::::::::::::::::::::::: :::
XP_005 NLQDIKTAGPQSQVLCGVVMDRSLVQDAPLSDCTETIEGLELTEQTFSPAKSLSFRKGEL
550 560 570 580 590 600
570 580 590 600 610 620
pF1KB3 VTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKE
610 620 630 640 650 660
630 640 650 660 670 680
pF1KB3 KSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPML
::::::::::::::::::::::
XP_005 KSPPDQPAVPHPPPSTPIKLEEGDGCAREYLLP
670 680 690
>>XP_016863197 (OMIM: 102680,145500) PREDICTED: alpha-ad (662 aa)
initn: 3599 init1: 3599 opt: 3642 Z-score: 1988.3 bits: 378.4 E(85289): 5.2e-104
Smith-Waterman score: 3970; 90.9% identity (90.9% similar) in 682 aa overlap (1-651:1-651)
10 20 30 40 50 60
pF1KB3 MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDH
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTK---------
430 440 450 460 470
490 500 510 520 530 540
pF1KB3 VKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
::::::::::::::::::::::::::::::::::::::
XP_016 ----------------------WTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQ
480 490 500
550 560
pF1KB3 NLQDIKTAGPQSQVLCGVVMDRSLVQ-------------------------------GEL
:::::::::::::::::::::::::: :::
XP_016 NLQDIKTAGPQSQVLCGVVMDRSLVQDAPLSDCTETIEGLELTEQTFSPAKSLSFRKGEL
510 520 530 540 550 560
570 580 590 600 610 620
pF1KB3 VTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKE
570 580 590 600 610 620
630 640 650 660 670 680
pF1KB3 KSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPML
::::::::::::::::::::::
XP_016 KSPPDQPAVPHPPPSTPIKLEEGDGCAREYLLP
630 640 650 660
768 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 02:37:28 2016 done: Fri Nov 4 02:37:30 2016
Total Scan time: 14.800 Total Display time: 0.270
Function used was FASTA [36.3.4 Apr, 2011]