Result of FASTA (omim) for
pF1KB3547
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3547, 1091 aa
1>>>pF1KB3547 1091 - 1091 aa - 1091 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9606+/-0.000493; mu= 18.2317+/- 0.030
mean_var=72.0562+/-15.217, 0's: 0 Z-trim(108.1): 57 B-trim: 726 in 1/49
Lambda= 0.151091
statistics sampled from 16160 (16215) to 16160 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.532), E-opt: 0.2 (0.19), width: 16
Scan time: 9.400
The best scores are: opt bits E(85289)
NP_000713 (OMIM: 114204) voltage-dependent calcium (1091) 7301 1601.8 0
XP_005250629 (OMIM: 114204) PREDICTED: voltage-dep (1086) 7246 1589.8 0
XP_005250630 (OMIM: 114204) PREDICTED: voltage-dep (1084) 7223 1584.8 0
XP_016868077 (OMIM: 114204) PREDICTED: voltage-dep (1052) 7050 1547.1 0
XP_011514874 (OMIM: 114204) PREDICTED: voltage-dep (1098) 6601 1449.2 0
XP_005250631 (OMIM: 114204) PREDICTED: voltage-dep (1079) 4033 889.5 0
NP_006021 (OMIM: 607082) voltage-dependent calcium (1143) 3954 872.2 0
XP_005265638 (OMIM: 607082) PREDICTED: voltage-dep (1144) 3952 871.8 0
NP_001005505 (OMIM: 607082) voltage-dependent calc (1145) 3937 868.5 0
NP_001278030 (OMIM: 607082) voltage-dependent calc (1076) 3907 862.0 0
XP_006716183 (OMIM: 114204) PREDICTED: voltage-dep (1071) 3832 845.6 0
XP_006716182 (OMIM: 114204) PREDICTED: voltage-dep (1085) 3832 845.6 0
XP_006716181 (OMIM: 114204) PREDICTED: voltage-dep (1110) 3832 845.6 0
XP_011514873 (OMIM: 114204) PREDICTED: voltage-dep (1105) 3830 845.2 0
XP_006716184 (OMIM: 114204) PREDICTED: voltage-dep ( 580) 3821 843.2 0
XP_011514872 (OMIM: 114204) PREDICTED: voltage-dep (1110) 3573 789.2 0
XP_005250627 (OMIM: 114204) PREDICTED: voltage-dep (1103) 3483 769.6 0
XP_011532545 (OMIM: 607082) PREDICTED: voltage-dep (1151) 3196 707.0 1.6e-202
NP_001167522 (OMIM: 607082) voltage-dependent calc (1150) 3186 704.8 7.1e-202
NP_001289819 (OMIM: 114204) voltage-dependent calc ( 309) 1898 423.9 7.2e-118
XP_005265375 (OMIM: 606399) PREDICTED: voltage-dep (1085) 1387 312.7 7.5e-84
NP_758952 (OMIM: 608171,610478) voltage-dependent (1137) 1291 291.8 1.6e-77
XP_011532255 (OMIM: 606399) PREDICTED: voltage-dep ( 617) 1079 245.5 7.4e-64
NP_060868 (OMIM: 606399) voltage-dependent calcium (1091) 1015 231.6 1.9e-59
XP_011519343 (OMIM: 608171,610478) PREDICTED: volt (1133) 988 225.7 1.2e-57
XP_011532250 (OMIM: 606399) PREDICTED: voltage-dep ( 819) 948 217.0 3.7e-55
XP_011532249 (OMIM: 606399) PREDICTED: voltage-dep (1012) 948 217.0 4.5e-55
XP_016862339 (OMIM: 606399) PREDICTED: voltage-dep (1061) 898 206.1 9e-52
XP_011532254 (OMIM: 606399) PREDICTED: voltage-dep ( 617) 894 205.1 1e-51
XP_011532253 (OMIM: 606399) PREDICTED: voltage-dep ( 619) 894 205.1 1e-51
XP_011532252 (OMIM: 606399) PREDICTED: voltage-dep ( 623) 894 205.1 1e-51
XP_011532251 (OMIM: 606399) PREDICTED: voltage-dep ( 653) 894 205.1 1.1e-51
XP_016862341 (OMIM: 606399) PREDICTED: voltage-dep ( 654) 894 205.1 1.1e-51
XP_011532248 (OMIM: 606399) PREDICTED: voltage-dep (1043) 894 205.2 1.6e-51
XP_016862340 (OMIM: 606399) PREDICTED: voltage-dep ( 914) 847 195.0 1.8e-48
XP_016862343 (OMIM: 606399) PREDICTED: voltage-dep ( 628) 533 126.5 5e-28
XP_016862342 (OMIM: 606399) PREDICTED: voltage-dep ( 631) 533 126.5 5e-28
XP_011532256 (OMIM: 606399) PREDICTED: voltage-dep ( 616) 528 125.4 1.1e-27
XP_011532257 (OMIM: 606399) PREDICTED: voltage-dep ( 603) 354 87.4 2.7e-16
NP_002208 (OMIM: 146650) inter-alpha-trypsin inhib ( 890) 211 56.3 9.3e-07
XP_005265162 (OMIM: 146650) PREDICTED: inter-alpha ( 927) 211 56.3 9.6e-07
NP_002207 (OMIM: 146640) inter-alpha-trypsin inhib ( 946) 167 46.7 0.00075
XP_016861845 (OMIM: 146650) PREDICTED: inter-alpha ( 596) 155 44.0 0.003
NP_001159921 (OMIM: 143890,600564) inter-alpha-try ( 900) 157 44.5 0.0033
NP_002209 (OMIM: 143890,600564) inter-alpha-trypsi ( 930) 157 44.5 0.0034
NP_002370 (OMIM: 115437) cartilage matrix protein ( 496) 150 42.9 0.0055
>>NP_000713 (OMIM: 114204) voltage-dependent calcium cha (1091 aa)
initn: 7301 init1: 7301 opt: 7301 Z-score: 8593.3 bits: 1601.8 E(85289): 0
Smith-Waterman score: 7301; 100.0% identity (100.0% similar) in 1091 aa overlap (1-1091:1-1091)
10 20 30 40 50 60
pF1KB3 MAAGCLLALTLTLFQSLLIGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MAAGCLLALTLTLFQSLLIGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 YEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 EVVYYNAKDDLDPEKNDSEPGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EVVYYNAKDDLDPEKNDSEPGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 NELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 RPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 VSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIML
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 FTDGGEERAQEIFNKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FTDGGEERAQEIFNKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 INTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 INTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 NQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKNPKSQEPVTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKNPKSQEPVTL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 DFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 ALVLPTYSFYYIKAKLEETITQARSKKGKMKDSETLKPDNFEESGYTFIAPRDYCNDLKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ALVLPTYSFYYIKAKLEETITQARSKKGKMKDSETLKPDNFEESGYTFIAPRDYCNDLKI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 SDNNTEFLLNFNEFIDRKTPNNPSCNADLINRVLLDAGFTNELVQNYWSKQKNIKGVKAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SDNNTEFLLNFNEFIDRKTPNNPSCNADLINRVLLDAGFTNELVQNYWSKQKNIKGVKAR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 FVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGAYESGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGAYESGI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 MVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVI
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 LDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAAPKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAAPKQ
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 GAGHRSAYVPSVADILQIGWWATAAAWSILQQFLLSLTFPRLLEAVEMEDDDFTASLSKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GAGHRSAYVPSVADILQIGWWATAAAWSILQQFLLSLTFPRLLEAVEMEDDDFTASLSKQ
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 SCITEQTQYFFDNDSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIMVESKGTCPCDTRLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SCITEQTQYFFDNDSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIMVESKGTCPCDTRLLI
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 QAEQTSDGPNPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWYIIGIQFLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QAEQTSDGPNPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWYIIGIQFLLL
1030 1040 1050 1060 1070 1080
1090
pF1KB3 WLVSGSTHRLL
:::::::::::
NP_000 WLVSGSTHRLL
1090
>>XP_005250629 (OMIM: 114204) PREDICTED: voltage-depende (1086 aa)
initn: 3789 init1: 3789 opt: 7246 Z-score: 8528.5 bits: 1589.8 E(85289): 0
Smith-Waterman score: 7246; 99.5% identity (99.5% similar) in 1091 aa overlap (1-1091:1-1086)
10 20 30 40 50 60
pF1KB3 MAAGCLLALTLTLFQSLLIGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAAGCLLALTLTLFQSLLIGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 YEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 EVVYYNAKDDLDPEKNDSEPGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVVYYNAKDDLDPEKNDSEPGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 NELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 RPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 VSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIML
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 FTDGGEERAQEIFNKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FTDGGEERAQEIFNKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 INTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 INTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 NQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKNPKSQEPVTL
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_005 NQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPK-----EPVTL
490 500 510 520 530
550 560 570 580 590 600
pF1KB3 DFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSL
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB3 ALVLPTYSFYYIKAKLEETITQARSKKGKMKDSETLKPDNFEESGYTFIAPRDYCNDLKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALVLPTYSFYYIKAKLEETITQARSKKGKMKDSETLKPDNFEESGYTFIAPRDYCNDLKI
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 SDNNTEFLLNFNEFIDRKTPNNPSCNADLINRVLLDAGFTNELVQNYWSKQKNIKGVKAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDNNTEFLLNFNEFIDRKTPNNPSCNADLINRVLLDAGFTNELVQNYWSKQKNIKGVKAR
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 FVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGAYESGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGAYESGI
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB3 MVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVI
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB3 LDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAAPKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAAPKQ
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB3 GAGHRSAYVPSVADILQIGWWATAAAWSILQQFLLSLTFPRLLEAVEMEDDDFTASLSKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GAGHRSAYVPSVADILQIGWWATAAAWSILQQFLLSLTFPRLLEAVEMEDDDFTASLSKQ
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB3 SCITEQTQYFFDNDSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIMVESKGTCPCDTRLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCITEQTQYFFDNDSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIMVESKGTCPCDTRLLI
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB3 QAEQTSDGPNPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWYIIGIQFLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QAEQTSDGPNPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWYIIGIQFLLL
1020 1030 1040 1050 1060 1070
1090
pF1KB3 WLVSGSTHRLL
:::::::::::
XP_005 WLVSGSTHRLL
1080
>>XP_005250630 (OMIM: 114204) PREDICTED: voltage-depende (1084 aa)
initn: 4088 init1: 4088 opt: 7223 Z-score: 8501.5 bits: 1584.8 E(85289): 0
Smith-Waterman score: 7223; 99.3% identity (99.3% similar) in 1091 aa overlap (1-1091:1-1084)
10 20 30 40 50 60
pF1KB3 MAAGCLLALTLTLFQSLLIGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAAGCLLALTLTLFQSLLIGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 YEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 EVVYYNAKDDLDPEKNDSEPGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVVYYNAKDDLDPEKNDSEPGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 NELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 RPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 VSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIML
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 FTDGGEERAQEIFNKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FTDGGEERAQEIFNKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 INTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 INTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 NQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKNPKSQEPVTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKNPKSQEPVTL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 DFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 ALVLPTYSFYYIKAKLEETITQARSKKGKMKDSETLKPDNFEESGYTFIAPRDYCNDLKI
:::::::::::::::::::::::: ::::::::::::::::::::::::::::
XP_005 ALVLPTYSFYYIKAKLEETITQARY-------SETLKPDNFEESGYTFIAPRDYCNDLKI
610 620 630 640 650
670 680 690 700 710 720
pF1KB3 SDNNTEFLLNFNEFIDRKTPNNPSCNADLINRVLLDAGFTNELVQNYWSKQKNIKGVKAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDNNTEFLLNFNEFIDRKTPNNPSCNADLINRVLLDAGFTNELVQNYWSKQKNIKGVKAR
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 FVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGAYESGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGAYESGI
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB3 MVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVI
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB3 LDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAAPKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAAPKQ
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB3 GAGHRSAYVPSVADILQIGWWATAAAWSILQQFLLSLTFPRLLEAVEMEDDDFTASLSKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GAGHRSAYVPSVADILQIGWWATAAAWSILQQFLLSLTFPRLLEAVEMEDDDFTASLSKQ
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB3 SCITEQTQYFFDNDSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIMVESKGTCPCDTRLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCITEQTQYFFDNDSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIMVESKGTCPCDTRLLI
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB3 QAEQTSDGPNPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWYIIGIQFLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QAEQTSDGPNPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWYIIGIQFLLL
1020 1030 1040 1050 1060 1070
1090
pF1KB3 WLVSGSTHRLL
:::::::::::
XP_005 WLVSGSTHRLL
1080
>>XP_016868077 (OMIM: 114204) PREDICTED: voltage-depende (1052 aa)
initn: 7050 init1: 7050 opt: 7050 Z-score: 8297.9 bits: 1547.1 E(85289): 0
Smith-Waterman score: 7050; 100.0% identity (100.0% similar) in 1052 aa overlap (40-1091:1-1052)
10 20 30 40 50 60
pF1KB3 TLTLFQSLLIGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDIYEKYQDLYT
::::::::::::::::::::::::::::::
XP_016 MQEDLVTLAKTASGVNQLVDIYEKYQDLYT
10 20 30
70 80 90 100 110 120
pF1KB3 VEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASNEVVYYNAKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASNEVVYYNAKD
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB3 DLDPEKNDSEPGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVLNELNWTSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLDPEKNDSEPGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVLNELNWTSAL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB3 DEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRRRPWYIQGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRRRPWYIQGAA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB3 SPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQDVSCFQHLVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQDVSCFQHLVQ
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB3 ANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIMLFTDGGEERA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIMLFTDGGEERA
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB3 QEIFNKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIRINTQEYLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEIFNKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIRINTQEYLDV
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB3 LGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLKNQLILGVMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLKNQLILGVMG
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB3 VDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKNPKSQEPVTLDFLDAELEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKNPKSQEPVTLDFLDAELEN
460 470 480 490 500 510
550 560 570 580 590 600
pF1KB3 DIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSLALVLPTYSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSLALVLPTYSF
520 530 540 550 560 570
610 620 630 640 650 660
pF1KB3 YYIKAKLEETITQARSKKGKMKDSETLKPDNFEESGYTFIAPRDYCNDLKISDNNTEFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYIKAKLEETITQARSKKGKMKDSETLKPDNFEESGYTFIAPRDYCNDLKISDNNTEFLL
580 590 600 610 620 630
670 680 690 700 710 720
pF1KB3 NFNEFIDRKTPNNPSCNADLINRVLLDAGFTNELVQNYWSKQKNIKGVKARFVVTDGGIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFNEFIDRKTPNNPSCNADLINRVLLDAGFTNELVQNYWSKQKNIKGVKARFVVTDGGIT
640 650 660 670 680 690
730 740 750 760 770 780
pF1KB3 RVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGAYESGIMVSKAVEIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGAYESGIMVSKAVEIY
700 710 720 730 740 750
790 800 810 820 830 840
pF1KB3 IQGKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVILDDGGFLLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQGKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVILDDGGFLLM
760 770 780 790 800 810
850 860 870 880 890 900
pF1KB3 ANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAAPKQGAGHRSAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAAPKQGAGHRSAYV
820 830 840 850 860 870
910 920 930 940 950 960
pF1KB3 PSVADILQIGWWATAAAWSILQQFLLSLTFPRLLEAVEMEDDDFTASLSKQSCITEQTQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSVADILQIGWWATAAAWSILQQFLLSLTFPRLLEAVEMEDDDFTASLSKQSCITEQTQY
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KB3 FFDNDSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIMVESKGTCPCDTRLLIQAEQTSDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFDNDSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIMVESKGTCPCDTRLLIQAEQTSDGP
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KB3 NPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWYIIGIQFLLLWLVSGSTHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWYIIGIQFLLLWLVSGSTHR
1000 1010 1020 1030 1040 1050
1090
pF1KB3 LL
::
XP_016 LL
>>XP_011514874 (OMIM: 114204) PREDICTED: voltage-depende (1098 aa)
initn: 6631 init1: 3483 opt: 6601 Z-score: 7768.6 bits: 1449.2 E(85289): 0
Smith-Waterman score: 7163; 97.7% identity (97.8% similar) in 1105 aa overlap (1-1091:1-1098)
10 20 30 40 50 60
pF1KB3 MAAGCLLALTLTLFQSLLIGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAGCLLALTLTLFQSLLIGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 YEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 EVVYYNAKDDLDPEKNDSEPGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVVYYNAKDDLDPEKNDSEPGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 NELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 RPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 VSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIML
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 FTDGGEERAQEIFNKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTDGGEERAQEIFNKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 INTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLK
430 440 450 460 470 480
490 500 510 520 530
pF1KB3 NQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPK----------
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKPIGVGIPTIN
490 500 510 520 530 540
540 550 560 570 580
pF1KB3 ----NPKSQEPVTLDFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNR
:. ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRKRRPNIQEPVTLDFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNR
550 560 570 580 590 600
590 600 610 620 630 640
pF1KB3 TYTWTPVNGTDYSLALVLPTYSFYYIKAKLEETITQARSKKGKMKDSETLKPDNFEESGY
:::::::::::::::::::::::::::::::::::::: ::::::::::::::
XP_011 TYTWTPVNGTDYSLALVLPTYSFYYIKAKLEETITQARY-------SETLKPDNFEESGY
610 620 630 640 650
650 660 670 680 690 700
pF1KB3 TFIAPRDYCNDLKISDNNTEFLLNFNEFIDRKTPNNPSCNADLINRVLLDAGFTNELVQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFIAPRDYCNDLKISDNNTEFLLNFNEFIDRKTPNNPSCNADLINRVLLDAGFTNELVQN
660 670 680 690 700 710
710 720 730 740 750 760
pF1KB3 YWSKQKNIKGVKARFVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YWSKQKNIKGVKARFVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAP
720 730 740 750 760 770
770 780 790 800 810 820
pF1KB3 YFNKSGPGAYESGIMVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFNKSGPGAYESGIMVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPV
780 790 800 810 820 830
830 840 850 860 870 880
pF1KB3 CDCKRNSDVMDCVILDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CDCKRNSDVMDCVILDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSY
840 850 860 870 880 890
890 900 910 920 930 940
pF1KB3 DYQSVCEPGAAPKQGAGHRSAYVPSVADILQIGWWATAAAWSILQQFLLSLTFPRLLEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYQSVCEPGAAPKQGAGHRSAYVPSVADILQIGWWATAAAWSILQQFLLSLTFPRLLEAV
900 910 920 930 940 950
950 960 970 980 990 1000
pF1KB3 EMEDDDFTASLSKQSCITEQTQYFFDNDSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EMEDDDFTASLSKQSCITEQTQYFFDNDSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIMV
960 970 980 990 1000 1010
1010 1020 1030 1040 1050 1060
pF1KB3 ESKGTCPCDTRLLIQAEQTSDGPNPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESKGTCPCDTRLLIQAEQTSDGPNPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLN
1020 1030 1040 1050 1060 1070
1070 1080 1090
pF1KB3 PSLWYIIGIQFLLLWLVSGSTHRLL
:::::::::::::::::::::::::
XP_011 PSLWYIIGIQFLLLWLVSGSTHRLL
1080 1090
>>XP_005250631 (OMIM: 114204) PREDICTED: voltage-depende (1079 aa)
initn: 6641 init1: 3493 opt: 4033 Z-score: 4743.5 bits: 889.5 E(85289): 0
Smith-Waterman score: 7168; 98.8% identity (98.8% similar) in 1091 aa overlap (1-1091:1-1079)
10 20 30 40 50 60
pF1KB3 MAAGCLLALTLTLFQSLLIGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAAGCLLALTLTLFQSLLIGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 YEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 EVVYYNAKDDLDPEKNDSEPGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVVYYNAKDDLDPEKNDSEPGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 NELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 RPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 VSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIML
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 FTDGGEERAQEIFNKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FTDGGEERAQEIFNKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 INTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 INTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 NQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKNPKSQEPVTL
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_005 NQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPK-----EPVTL
490 500 510 520 530
550 560 570 580 590 600
pF1KB3 DFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSL
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB3 ALVLPTYSFYYIKAKLEETITQARSKKGKMKDSETLKPDNFEESGYTFIAPRDYCNDLKI
:::::::::::::::::::::::: ::::::::::::::::::::::::::::
XP_005 ALVLPTYSFYYIKAKLEETITQARY-------SETLKPDNFEESGYTFIAPRDYCNDLKI
600 610 620 630 640
670 680 690 700 710 720
pF1KB3 SDNNTEFLLNFNEFIDRKTPNNPSCNADLINRVLLDAGFTNELVQNYWSKQKNIKGVKAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDNNTEFLLNFNEFIDRKTPNNPSCNADLINRVLLDAGFTNELVQNYWSKQKNIKGVKAR
650 660 670 680 690 700
730 740 750 760 770 780
pF1KB3 FVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGAYESGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGAYESGI
710 720 730 740 750 760
790 800 810 820 830 840
pF1KB3 MVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVI
770 780 790 800 810 820
850 860 870 880 890 900
pF1KB3 LDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAAPKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAAPKQ
830 840 850 860 870 880
910 920 930 940 950 960
pF1KB3 GAGHRSAYVPSVADILQIGWWATAAAWSILQQFLLSLTFPRLLEAVEMEDDDFTASLSKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GAGHRSAYVPSVADILQIGWWATAAAWSILQQFLLSLTFPRLLEAVEMEDDDFTASLSKQ
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KB3 SCITEQTQYFFDNDSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIMVESKGTCPCDTRLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCITEQTQYFFDNDSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIMVESKGTCPCDTRLLI
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KB3 QAEQTSDGPNPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWYIIGIQFLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QAEQTSDGPNPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWYIIGIQFLLL
1010 1020 1030 1040 1050 1060
1090
pF1KB3 WLVSGSTHRLL
:::::::::::
XP_005 WLVSGSTHRLL
1070
>>NP_006021 (OMIM: 607082) voltage-dependent calcium cha (1143 aa)
initn: 3297 init1: 779 opt: 3954 Z-score: 4650.0 bits: 872.2 E(85289): 0
Smith-Waterman score: 3954; 54.6% identity (78.9% similar) in 1097 aa overlap (7-1080:44-1124)
10 20 30
pF1KB3 MAAGCLLALTLTLFQSLLIGP-SSEEPFPSAVTIKS
: : : :. :: .: .: ::. :..
NP_006 GPARTARPWPGCGPHPGPGTRRPTSGPPRPLWLLLPLLP-LLAAPGASAYSFPQQHTMQH
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB3 WVDKMQEDLVTLAKTASGVNQLVDIYEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSK
:. ...... . . .::.:: .::. ..:. :. :. ..::: .: :::.::. . .
NP_006 WARRLEQEVDGVMRIFGGVQQLREIYKDNRNLFEVQENEPQKLVEKVAGDIESLLDRKVQ
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB3 ALVRLALEAEKVQAAHQWREDFASNEVVYYNAKDDL---DPEKNDSEPGSQ--RIKPVFI
:: ::: ::. : ::.:.... ...:::.:: : :::..: : ::. .. ::
NP_006 ALKRLADAAENFQKAHRWQDNIKEEDIVYYDAKADAELDDPESEDVERGSKASTLRLDFI
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB3 EDANFGRQISYQHAAVHIPTDIYEGSTIVLNELNWTSALDEVFKKNREEDPSLLWQVFGS
:: :: ...:..:::.::::::.:::..::::::: ::..:: .::..::.::::::::
NP_006 EDPNFKNKVNYSYAAVQIPTDIYKGSTVILNELNWTEALENVFMENRRQDPTLLWQVFGS
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB3 ATGLARYYPASPWVDNSRTPNKIDLYDVRRRPWYIQGAASPKDMLILVDVSGSVSGLTLK
:::..:::::.:: :.:.:::::::::::::::::.:::::.:.:::::::::::::
NP_006 ATGVTRYYPATPW----RAPKKIDLYDVRRRPWYIQGASSPKDMVIIVDVSGSVSGLTLK
260 270 280 290 300
280 290 300 310 320 330
pF1KB3 LIRTSVSEMLETLSDDDFVNVASFNSNAQDVSCFQHLVQANVRNKKVLKDAVNNITAKGI
:..::: :::.::::::.::::::: .:: :::: ::::::::::::.:.::....:::
NP_006 LMKTSVCEMLDTLSDDDYVNVASFNEKAQPVSCFTHLVQANVRNKKVFKEAVQGMVAKGT
310 320 330 340 350 360
340 350 360 370 380
pF1KB3 TDYKKGFSFAFEQLLNYNVSRANCNKIIMLFTDGGEERAQEIFNKYN-KDKKVRVFTFSV
: :: :: .::.:: : :..::::::.::.::::::.:.:..:.::: .. ::::::::
NP_006 TGYKAGFEYAFDQLQNSNITRANCNKMIMMFTDGGEDRVQDVFEKYNWPNRTVRVFTFSV
370 380 390 400 410 420
390 400 410 420 430 440
pF1KB3 GQHNYDRGPIQWMACENKGYYYEIPSIGAIRINTQEYLDVLGRPMVLAGDKAKQVQWTNV
:::::: :.::::: :::::.::::::::::::::::::::::::::: .:::::::::
NP_006 GQHNYDVTPLQWMACANKGYYFEIPSIGAIRINTQEYLDVLGRPMVLAGKEAKQVQWTNV
430 440 450 460 470 480
450 460 470 480 490 500
pF1KB3 YLDALELGLVITGTLPVFNITGQFENKTNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPN
: ::: ::::.::::::::.: .. . ::::::::::.::.:.::::::: .:: :
NP_006 YEDALGLGLVVTGTLPVFNLTQ--DGPGEKKNQLILGVMGIDVALNDIKRLTPNYTLGAN
490 500 510 520 530 540
510 520 530 540 550 560
pF1KB3 GYYFAIDPNGYVLLHPNLQPKNPKSQEPVTLDFLDAELENDIKVEIRNKMIDGESGEKTF
:: :::: ::::::::::.:.. . .:::::::::::::.. : ::: .::::..:.: .
NP_006 GYVFAIDLNGYVLLHPNLKPQTTNFREPVTLDFLDAELEDENKEEIRRSMIDGNKGHKQI
550 560 570 580 590 600
570 580 590 600 610 620
pF1KB3 RTLVKSQDERYIDKGNRTYTWTPVNGTDYSLALVLPTYSFYYIKAKLEETITQARSKKGK
:::::: ::::::. .:.:::.:. .:.:::.:::: :: .:..:.: . : :
NP_006 RTLVKSLDERYIDEVTRNYTWVPIRSTNYSLGLVLPPYSTFYLQANLSDQILQ-------
610 620 630 640 650
630 640 650 660 670 680
pF1KB3 MKDSETLKPDNFEESGYTFIAPRDYCNDLKISDNNTEFLLNFNEFIDRKTPNNPSCNADL
.: : : :..:: :..:::::.::.::. :::::::: :: :.... ::.. .:: :
NP_006 VKYFEFLLPSSFESEGHVFIAPREYCKDLNASDNNTEFLKNFIELMEKVTPDSKQCNNFL
660 670 680 690 700 710
690 700 710 720 730 740
pF1KB3 INRVLLDAGFTNELVQNYWSKQK-NIKGVKARFVVTDGGITRVYPKEAGENWQENPETYE
.. ..::.:.:..::. : : : .. : :..::::::::.:..:.:.: :::: ..
NP_006 LHNLILDTGITQQLVERVWRDQDLNTYSLLAVFAATDGGITRVFPNKAAEDWTENPEPFN
720 730 740 750 760 770
750 760 770 780 790 800
pF1KB3 DSFYKRSLDNDNYVFTAPYFNKS-GPGAYES---GIMVSKAVEIYIQGKLLKPAVVGIKI
:::.::::: .::: :. . : :. ::.:: :::. . . :.:::::.:.
NP_006 ASFYRRSLDNHGYVFKPPHQDALLRPLELENDTVGILVSTAVELSLGRRTLRPAVVGVKL
780 790 800 810 820 830
810 820 830 840 850
pF1KB3 DVNSWIENF-----TKTSIRDP--CAGPV--C--DCKRNSDVMDCVILDDGGFLLMANHD
:...: :.: ..: .: : :: : ::. :.. . ::..::::::...:..
NP_006 DLEAWAEKFKVLASNRTHQDQPQKC-GPNSHCEMDCEVNNEDLLCVLIDDGGFLVLSNQN
840 850 860 870 880 890
860 870 880 890 900 910
pF1KB3 DYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAAPKQGAGHRSAYVPSVA
.:.::::.:.: .:: : : : :. ..:::::..: : . ::. :...::.::
NP_006 HQWDQVGRFFSEVDANLMLALYNNSFYTRKESYDYQAACAPQPPGNLGAAPRGVFVPTVA
900 910 920 930 940 950
920 930 940 950 960 970
pF1KB3 DILQIGWWATAAAWSILQQFLLSLTFPRLLEAVEMEDDDFTASLSKQSCITEQTQYFFDN
:.:...::..:::::..::.: .: . ..: : . . ..::. .::::.: .
NP_006 DFLNLAWWTSAAAWSLFQQLLYGLIYHSWFQADPAEAEG-SPETRESSCVMKQTQYYFGS
960 970 980 990 1000 1010
980 990 1000 1010 1020 1030
pF1KB3 DSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIMVESKGTCPCDTRLLIQAEQTSDGPNPCD
. :.....:::::::.::...: ::::.:...:. :.. :.: : ::::. :.
NP_006 VNASYNAIIDCGNCSRLFHAQRLTNTNLLFVVAEKPLCSQCEAGRLLQKETHSDGPEQCE
1020 1030 1040 1050 1060 1070
1040 1050 1060 1070 1080 1090
pF1KB3 MVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWYIIGIQFLLLWLVSGSTHRLL
.:..::::.:: .::: :. :: .::: ... ::: ....:.:::
NP_006 LVQRPRYRRGPHICFDYNATEDTSDCGRGASFPPSLGVLVSLQLLLLLGLPPRPQPQVLV
1080 1090 1100 1110 1120 1130
NP_006 HASRRL
1140
>>XP_005265638 (OMIM: 607082) PREDICTED: voltage-depende (1144 aa)
initn: 3314 init1: 779 opt: 3952 Z-score: 4647.7 bits: 871.8 E(85289): 0
Smith-Waterman score: 3952; 54.6% identity (78.9% similar) in 1098 aa overlap (7-1080:44-1125)
10 20 30
pF1KB3 MAAGCLLALTLTLFQSLLIGP-SSEEPFPSAVTIKS
: : : :. :: .: .: ::. :..
XP_005 GPARTARPWPGCGPHPGPGTRRPTSGPPRPLWLLLPLLP-LLAAPGASAYSFPQQHTMQH
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB3 WVDKMQEDLVTLAKTASGVNQLVDIYEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSK
:. ...... . . .::.:: .::. ..:. :. :. ..::: .: :::.::. . .
XP_005 WARRLEQEVDGVMRIFGGVQQLREIYKDNRNLFEVQENEPQKLVEKVAGDIESLLDRKVQ
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB3 ALVRLALEAEKVQAAHQWREDFASNEVVYYNAKDDL---DPEKNDSEPGSQ--RIKPVFI
:: ::: ::. : ::.:.... ...:::.:: : :::..: : ::. .. ::
XP_005 ALKRLADAAENFQKAHRWQDNIKEEDIVYYDAKADAELDDPESEDVERGSKASTLRLDFI
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB3 EDANFGRQISYQHAAVHIPTDIYEGSTIVLNELNWTSALDEVFKKNREEDPSLLWQVFGS
:: :: ...:..:::.::::::.:::..::::::: ::..:: .::..::.::::::::
XP_005 EDPNFKNKVNYSYAAVQIPTDIYKGSTVILNELNWTEALENVFMENRRQDPTLLWQVFGS
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB3 ATGLARYYPASPWVDNSRTPNKIDLYDVRRRPWYIQGAASPKDMLILVDVSGSVSGLTLK
:::..:::::.:: :.:.:::::::::::::::::.:::::.:.:::::::::::::
XP_005 ATGVTRYYPATPW----RAPKKIDLYDVRRRPWYIQGASSPKDMVIIVDVSGSVSGLTLK
260 270 280 290 300
280 290 300 310 320 330
pF1KB3 LIRTSVSEMLETLSDDDFVNVASFNSNAQDVSCFQHLVQANVRNKKVLKDAVNNITAKGI
:..::: :::.::::::.::::::: .:: :::: ::::::::::::.:.::....:::
XP_005 LMKTSVCEMLDTLSDDDYVNVASFNEKAQPVSCFTHLVQANVRNKKVFKEAVQGMVAKGT
310 320 330 340 350 360
340 350 360 370 380
pF1KB3 TDYKKGFSFAFEQLLNYNVSRANCNKIIMLFTDGGEERAQEIFNKYN-KDKKVRVFTFSV
: :: :: .::.:: : :..::::::.::.::::::.:.:..:.::: .. ::::::::
XP_005 TGYKAGFEYAFDQLQNSNITRANCNKMIMMFTDGGEDRVQDVFEKYNWPNRTVRVFTFSV
370 380 390 400 410 420
390 400 410 420 430 440
pF1KB3 GQHNYDRGPIQWMACENKGYYYEIPSIGAIRINTQEYLDVLGRPMVLAGDKAKQVQWTNV
:::::: :.::::: :::::.::::::::::::::::::::::::::: .:::::::::
XP_005 GQHNYDVTPLQWMACANKGYYFEIPSIGAIRINTQEYLDVLGRPMVLAGKEAKQVQWTNV
430 440 450 460 470 480
450 460 470 480 490 500
pF1KB3 YLDALELGLVITGTLPVFNITGQFENKTNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPN
: ::: ::::.::::::::.: .. . ::::::::::.::.:.::::::: .:: :
XP_005 YEDALGLGLVVTGTLPVFNLTQ--DGPGEKKNQLILGVMGIDVALNDIKRLTPNYTLGAN
490 500 510 520 530 540
510 520 530 540 550 560
pF1KB3 GYYFAIDPNGYVLLHPNLQPKNPKSQEPVTLDFLDAELENDIKVEIRNKMIDGESGEKTF
:: :::: ::::::::::.:.. . .:::::::::::::.. : ::: .::::..:.: .
XP_005 GYVFAIDLNGYVLLHPNLKPQTTNFREPVTLDFLDAELEDENKEEIRRSMIDGNKGHKQI
550 560 570 580 590 600
570 580 590 600 610 620
pF1KB3 RTLVKSQDERYIDKGNRTYTWTPVNGTDYSLALVLPTYSFYYIKAKLEETITQARSKKGK
:::::: ::::::. .:.:::.:. .:.:::.:::: :: .:..:.: . : :
XP_005 RTLVKSLDERYIDEVTRNYTWVPIRSTNYSLGLVLPPYSTFYLQANLSDQILQ-------
610 620 630 640 650
630 640 650 660 670 680
pF1KB3 MKDSETLKPDNFEESGYTFIAPRDYCNDLKISDNNTEFLLNFNEFIDRKTPNNPSCNADL
.: : : :..:: :..:::::.::.::. :::::::: :: :.... ::.. .:: :
XP_005 VKYFEFLLPSSFESEGHVFIAPREYCKDLNASDNNTEFLKNFIELMEKVTPDSKQCNNFL
660 670 680 690 700 710
690 700 710 720 730 740
pF1KB3 INRVLLDAGFTNELVQNYWSKQK-NIKGVKARFVVTDGGITRVYPKEAGENWQENPETYE
.. ..::.:.:..::. : : : .. : :..::::::::.:..:.:.: :::: ..
XP_005 LHNLILDTGITQQLVERVWRDQDLNTYSLLAVFAATDGGITRVFPNKAAEDWTENPEPFN
720 730 740 750 760 770
750 760 770 780 790 800
pF1KB3 DSFYKRSLDNDNYVFTAPYFNKS-GPGAYES---GIMVSKAVEIYIQGKLLKPAVVGIKI
:::.::::: .::: :. . : :. ::.:: :::. . . :.:::::.:.
XP_005 ASFYRRSLDNHGYVFKPPHQDALLRPLELENDTVGILVSTAVELSLGRRTLRPAVVGVKL
780 790 800 810 820 830
810 820 830 840 850
pF1KB3 DVNSWIENF-----TKTSIRDP---CAGPV--C--DCKRNSDVMDCVILDDGGFLLMANH
:...: :.: ..: .: : :: : ::. :.. . ::..::::::...:.
XP_005 DLEAWAEKFKVLASNRTHQDQPQKQC-GPNSHCEMDCEVNNEDLLCVLIDDGGFLVLSNQ
840 850 860 870 880 890
860 870 880 890 900 910
pF1KB3 DDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAAPKQGAGHRSAYVPSV
. .:.::::.:.: .:: : : : :. ..:::::..: : . ::. :...::.:
XP_005 NHQWDQVGRFFSEVDANLMLALYNNSFYTRKESYDYQAACAPQPPGNLGAAPRGVFVPTV
900 910 920 930 940 950
920 930 940 950 960 970
pF1KB3 ADILQIGWWATAAAWSILQQFLLSLTFPRLLEAVEMEDDDFTASLSKQSCITEQTQYFFD
::.:...::..:::::..::.: .: . ..: : . . ..::. .::::.:
XP_005 ADFLNLAWWTSAAAWSLFQQLLYGLIYHSWFQADPAEAEG-SPETRESSCVMKQTQYYFG
960 970 980 990 1000 1010
980 990 1000 1010 1020 1030
pF1KB3 NDSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIMVESKGTCPCDTRLLIQAEQTSDGPNPC
. . :.....:::::::.::...: ::::.:...:. :.. :.: : ::::. :
XP_005 SVNASYNAIIDCGNCSRLFHAQRLTNTNLLFVVAEKPLCSQCEAGRLLQKETHSDGPEQC
1020 1030 1040 1050 1060 1070
1040 1050 1060 1070 1080 1090
pF1KB3 DMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWYIIGIQFLLLWLVSGSTHRLL
..:..::::.:: .::: :. :: .::: ... ::: ....:.:::
XP_005 ELVQRPRYRRGPHICFDYNATEDTSDCGRGASFPPSLGVLVSLQLLLLLGLPPRPQPQVL
1080 1090 1100 1110 1120 1130
XP_005 VHASRRL
1140
>>NP_001005505 (OMIM: 607082) voltage-dependent calcium (1145 aa)
initn: 3345 init1: 779 opt: 3937 Z-score: 4630.0 bits: 868.5 E(85289): 0
Smith-Waterman score: 3937; 54.4% identity (78.8% similar) in 1099 aa overlap (7-1080:44-1126)
10 20 30
pF1KB3 MAAGCLLALTLTLFQSLLIGP-SSEEPFPSAVTIKS
: : : :. :: .: .: ::. :..
NP_001 GPARTARPWPGCGPHPGPGTRRPTSGPPRPLWLLLPLLP-LLAAPGASAYSFPQQHTMQH
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB3 WVDKMQEDLVTLAKTASGVNQLVDIYEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSK
:. ...... . . .::.:: .::. ..:. :. :. ..::: .: :::.::. . .
NP_001 WARRLEQEVDGVMRIFGGVQQLREIYKDNRNLFEVQENEPQKLVEKVAGDIESLLDRKVQ
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB3 ALVRLALEAEKVQAAHQWREDFASNEVVYYNAKDDL---DPEKNDSEPGSQ--RIKPVFI
:: ::: ::. : ::.:.... ...:::.:: : :::..: : ::. .. ::
NP_001 ALKRLADAAENFQKAHRWQDNIKEEDIVYYDAKADAELDDPESEDVERGSKASTLRLDFI
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB3 EDANFGRQISYQHAAVHIPTDIYEGSTIVLNELNWTSALDEVFKKNREEDPSLLWQVFGS
:: :: ...:..:::.::::::.:::..::::::: ::..:: .::..::.::::::::
NP_001 EDPNFKNKVNYSYAAVQIPTDIYKGSTVILNELNWTEALENVFMENRRQDPTLLWQVFGS
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB3 ATGLARYYPASPWVDNSRTPNKIDLYDVRRRPWYIQGAASPKDMLILVDVSGSVSGLTLK
:::..:::::.:: :.:.:::::::::::::::::.:::::.:.:::::::::::::
NP_001 ATGVTRYYPATPW----RAPKKIDLYDVRRRPWYIQGASSPKDMVIIVDVSGSVSGLTLK
260 270 280 290 300
280 290 300 310 320 330
pF1KB3 LIRTSVSEMLETLSDDDFVNVASFNSNAQDVSCFQHLVQANVRNKKVLKDAVNNITAKGI
:..::: :::.::::::.::::::: .:: :::: ::::::::::::.:.::....:::
NP_001 LMKTSVCEMLDTLSDDDYVNVASFNEKAQPVSCFTHLVQANVRNKKVFKEAVQGMVAKGT
310 320 330 340 350 360
340 350 360 370 380
pF1KB3 TDYKKGFSFAFEQLLNYNVSRANCNKIIMLFTDGGEERAQEIFNKYN-KDKKVRVFTFSV
: :: :: .::.:: : :..::::::.::.::::::.:.:..:.::: .. ::::::::
NP_001 TGYKAGFEYAFDQLQNSNITRANCNKMIMMFTDGGEDRVQDVFEKYNWPNRTVRVFTFSV
370 380 390 400 410 420
390 400 410 420 430 440
pF1KB3 GQHNYDRGPIQWMACENKGYYYEIPSIGAIRINTQEYLDVLGRPMVLAGDKAKQVQWTNV
:::::: :.::::: :::::.::::::::::::::::::::::::::: .:::::::::
NP_001 GQHNYDVTPLQWMACANKGYYFEIPSIGAIRINTQEYLDVLGRPMVLAGKEAKQVQWTNV
430 440 450 460 470 480
450 460 470 480 490 500
pF1KB3 YLDALELGLVITGTLPVFNITGQFENKTNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPN
: ::: ::::.::::::::.: .. . ::::::::::.::.:.::::::: .:: :
NP_001 YEDALGLGLVVTGTLPVFNLTQ--DGPGEKKNQLILGVMGIDVALNDIKRLTPNYTLGAN
490 500 510 520 530 540
510 520 530 540 550 560
pF1KB3 GYYFAIDPNGYVLLHPNLQPKNPKSQEPVTLDFLDAELENDIKVEIRNKMIDGESGEKTF
:: :::: ::::::::::.:.. . .:::::::::::::.. : ::: .::::..:.: .
NP_001 GYVFAIDLNGYVLLHPNLKPQTTNFREPVTLDFLDAELEDENKEEIRRSMIDGNKGHKQI
550 560 570 580 590 600
570 580 590 600 610 620
pF1KB3 RTLVKSQDERYIDKGNRTYTWTPVNGTDYSLALVLPTYSFYYIKAKLEETITQARSKKGK
:::::: ::::::. .:.:::.:. .:.:::.:::: :: .:..:.: . : :
NP_001 RTLVKSLDERYIDEVTRNYTWVPIRSTNYSLGLVLPPYSTFYLQANLSDQILQ-------
610 620 630 640 650
630 640 650 660 670 680
pF1KB3 MKDSETLKPDNFEESGYTFIAPRDYCNDLKISDNNTEFLLNFNEFIDRKTPNNPSCNADL
.: : : :..:: :..:::::.::.::. :::::::: :: :.... ::.. .:: :
NP_001 VKYFEFLLPSSFESEGHVFIAPREYCKDLNASDNNTEFLKNFIELMEKVTPDSKQCNNFL
660 670 680 690 700 710
690 700 710 720 730 740
pF1KB3 INRVLLDAGFTNELVQNYWSKQK-NIKGVKARFVVTDGGITRVYPKEAGENWQENPETYE
.. ..::.:.:..::. : : : .. : :..::::::::.:..:.:.: :::: ..
NP_001 LHNLILDTGITQQLVERVWRDQDLNTYSLLAVFAATDGGITRVFPNKAAEDWTENPEPFN
720 730 740 750 760 770
750 760 770 780 790 800
pF1KB3 DSFYKRSLDNDNYVFTAPYFNKS-GPGAYES---GIMVSKAVEIYIQGKLLKPAVVGIKI
:::.::::: .::: :. . : :. ::.:: :::. . . :.:::::.:.
NP_001 ASFYRRSLDNHGYVFKPPHQDALLRPLELENDTVGILVSTAVELSLGRRTLRPAVVGVKL
780 790 800 810 820 830
810 820 830 840 850
pF1KB3 DVNSWIENF-----TKTSIRDP--CAGPV--C--DCKRNSDVMDCVILDDGGFLLMANHD
:...: :.: ..: .: : :: : ::. :.. . ::..::::::...:..
NP_001 DLEAWAEKFKVLASNRTHQDQPQKC-GPNSHCEMDCEVNNEDLLCVLIDDGGFLVLSNQN
840 850 860 870 880 890
860 870 880 890 900 910
pF1KB3 DYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAAPKQGAGHRSAYVPSVA
.:.::::.:.: .:: : : : :. ..:::::..: : . ::. :...::.::
NP_001 HQWDQVGRFFSEVDANLMLALYNNSFYTRKESYDYQAACAPQPPGNLGAAPRGVFVPTVA
900 910 920 930 940 950
920 930 940 950 960 970
pF1KB3 DILQIGWWATAAAWSILQQFLLSLTFPRLLEAVEMEDDDFTASLSKQSCITEQTQYFFDN
:.:...::..:::::..::.: .: . ..: : . . ..::. .::::.: .
NP_001 DFLNLAWWTSAAAWSLFQQLLYGLIYHSWFQADPAEAEG-SPETRESSCVMKQTQYYFGS
960 970 980 990 1000 1010
980 990 1000 1010 1020 1030
pF1KB3 DSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIMVESKGTCPCDTRLLIQAEQ--TSDGPNP
. :.....:::::::.::...: ::::.:...:. :.. :.: : .:::.
NP_001 VNASYNAIIDCGNCSRLFHAQRLTNTNLLFVVAEKPLCSQCEAGRLLQKETHCPADGPEQ
1020 1030 1040 1050 1060 1070
1040 1050 1060 1070 1080 1090
pF1KB3 CDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWYIIGIQFLLLWLVSGSTHRLL
:..:..::::.:: .::: :. :: .::: ... ::: ....:.:::
NP_001 CELVQRPRYRRGPHICFDYNATEDTSDCGRGASFPPSLGVLVSLQLLLLLGLPPRPQPQV
1080 1090 1100 1110 1120 1130
NP_001 LVHASRRL
1140
>>NP_001278030 (OMIM: 607082) voltage-dependent calcium (1076 aa)
initn: 3345 init1: 779 opt: 3907 Z-score: 4595.1 bits: 862.0 E(85289): 0
Smith-Waterman score: 3907; 54.8% identity (79.4% similar) in 1072 aa overlap (33-1080:1-1057)
10 20 30 40 50 60
pF1KB3 AGCLLALTLTLFQSLLIGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDIYE
.. :. ...... . . .::.:: .::.
NP_001 MQHWARRLEQEVDGVMRIFGGVQQLREIYK
10 20 30
70 80 90 100 110 120
pF1KB3 KYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASNEV
..:. :. :. ..::: .: :::.::. . .:: ::: ::. : ::.:.... ...
NP_001 DNRNLFEVQENEPQKLVEKVAGDIESLLDRKVQALKRLADAAENFQKAHRWQDNIKEEDI
40 50 60 70 80 90
130 140 150 160 170
pF1KB3 VYYNAKDDL---DPEKNDSEPGSQ--RIKPVFIEDANFGRQISYQHAAVHIPTDIYEGST
:::.:: : :::..: : ::. .. :::: :: ...:..:::.::::::.:::
NP_001 VYYDAKADAELDDPESEDVERGSKASTLRLDFIEDPNFKNKVNYSYAAVQIPTDIYKGST
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB3 IVLNELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYD
..::::::: ::..:: .::..::.:::::::::::..:::::.:: :.:.::::::
NP_001 VILNELNWTEALENVFMENRRQDPTLLWQVFGSATGVTRYYPATPW----RAPKKIDLYD
160 170 180 190 200
240 250 260 270 280 290
pF1KB3 VRRRPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSN
:::::::::::.:::::.:.::::::::::::::..::: :::.::::::.::::::: .
NP_001 VRRRPWYIQGASSPKDMVIIVDVSGSVSGLTLKLMKTSVCEMLDTLSDDDYVNVASFNEK
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB3 AQDVSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKI
:: :::: ::::::::::::.:.::....::: : :: :: .::.:: : :..::::::.
NP_001 AQPVSCFTHLVQANVRNKKVFKEAVQGMVAKGTTGYKAGFEYAFDQLQNSNITRANCNKM
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB3 IMLFTDGGEERAQEIFNKYN-KDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSI
::.::::::.:.:..:.::: .. :::::::::::::: :.::::: :::::.:::::
NP_001 IMMFTDGGEDRVQDVFEKYNWPNRTVRVFTFSVGQHNYDVTPLQWMACANKGYYFEIPSI
330 340 350 360 370 380
420 430 440 450 460 470
pF1KB3 GAIRINTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENK
:::::::::::::::::::::: .:::::::::: ::: ::::.::::::::.: ..
NP_001 GAIRINTQEYLDVLGRPMVLAGKEAKQVQWTNVYEDALGLGLVVTGTLPVFNLTQ--DGP
390 400 410 420 430 440
480 490 500 510 520 530
pF1KB3 TNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKNPKSQE
. ::::::::::.::.:.::::::: .:: ::: :::: ::::::::::.:.. . .:
NP_001 GEKKNQLILGVMGIDVALNDIKRLTPNYTLGANGYVFAIDLNGYVLLHPNLKPQTTNFRE
450 460 470 480 490 500
540 550 560 570 580 590
pF1KB3 PVTLDFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGT
::::::::::::.. : ::: .::::..:.: .:::::: ::::::. .:.:::.:. .:
NP_001 PVTLDFLDAELEDENKEEIRRSMIDGNKGHKQIRTLVKSLDERYIDEVTRNYTWVPIRST
510 520 530 540 550 560
600 610 620 630 640 650
pF1KB3 DYSLALVLPTYSFYYIKAKLEETITQARSKKGKMKDSETLKPDNFEESGYTFIAPRDYCN
.:::.:::: :: .:..:.: . : : .: : : :..:: :..:::::.::.
NP_001 NYSLGLVLPPYSTFYLQANLSDQILQ-------VKYFEFLLPSSFESEGHVFIAPREYCK
570 580 590 600 610
660 670 680 690 700 710
pF1KB3 DLKISDNNTEFLLNFNEFIDRKTPNNPSCNADLINRVLLDAGFTNELVQNYWSKQK-NIK
::. :::::::: :: :.... ::.. .:: :.. ..::.:.:..::. : : :
NP_001 DLNASDNNTEFLKNFIELMEKVTPDSKQCNNFLLHNLILDTGITQQLVERVWRDQDLNTY
620 630 640 650 660 670
720 730 740 750 760 770
pF1KB3 GVKARFVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKS-GPG
.. : :..::::::::.:..:.:.: :::: .. :::.::::: .::: :. . :
NP_001 SLLAVFAATDGGITRVFPNKAAEDWTENPEPFNASFYRRSLDNHGYVFKPPHQDALLRPL
680 690 700 710 720 730
780 790 800 810 820
pF1KB3 AYES---GIMVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENF-----TKTSIRDP--CAG
:. ::.:: :::. . . :.:::::.:.:...: :.: ..: .: : :
NP_001 ELENDTVGILVSTAVELSLGRRTLRPAVVGVKLDLEAWAEKFKVLASNRTHQDQPQKC-G
740 750 760 770 780 790
830 840 850 860 870 880
pF1KB3 PV--C--DCKRNSDVMDCVILDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVNISVY
: : ::. :.. . ::..::::::...:.. .:.::::.:.: .:: : : : :
NP_001 PNSHCEMDCEVNNEDLLCVLIDDGGFLVLSNQNHQWDQVGRFFSEVDANLMLALYNNSFY
800 810 820 830 840 850
890 900 910 920 930 940
pF1KB3 AFNKSYDYQSVCEPGAAPKQGAGHRSAYVPSVADILQIGWWATAAAWSILQQFLLSLTFP
. ..:::::..: : . ::. :...::.:::.:...::..:::::..::.: .: .
NP_001 TRKESYDYQAACAPQPPGNLGAAPRGVFVPTVADFLNLAWWTSAAAWSLFQQLLYGLIYH
860 870 880 890 900 910
950 960 970 980 990 1000
pF1KB3 RLLEAVEMEDDDFTASLSKQSCITEQTQYFFDNDSKSFSGVLDCGNCSRIFHGEKLMNTN
..: : . . ..::. .::::.: . . :.....:::::::.::...: :::
NP_001 SWFQADPAEAEG-SPETRESSCVMKQTQYYFGSVNASYNAIIDCGNCSRLFHAQRLTNTN
920 930 940 950 960 970
1010 1020 1030 1040 1050
pF1KB3 LIFIMVESKGTCPCDTRLLIQAEQ--TSDGPNPCDMVKQPRYRKGPDVCFDNNVLEDYTD
:.:...:. :.. :.: : .:::. :..:..::::.:: .::: :. :: .:
NP_001 LLFVVAEKPLCSQCEAGRLLQKETHCPADGPEQCELVQRPRYRRGPHICFDYNATEDTSD
980 990 1000 1010 1020 1030
1060 1070 1080 1090
pF1KB3 CGGVSGLNPSLWYIIGIQFLLLWLVSGSTHRLL
:: ... ::: ....:.:::
NP_001 CGRGASFPPSLGVLVSLQLLLLLGLPPRPQPQVLVHASRRL
1040 1050 1060 1070
1091 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 17:11:30 2016 done: Tue Nov 8 17:11:32 2016
Total Scan time: 9.400 Total Display time: 0.460
Function used was FASTA [36.3.4 Apr, 2011]