Result of FASTA (omim) for
pF1KB3404
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3404, 1691 aa
1>>>pF1KB3404 1691 - 1691 aa - 1691 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.7018+/-0.000745; mu= -22.1247+/- 0.046
mean_var=1123.6833+/-236.034, 0's: 0 Z-trim(117.6): 1185 B-trim: 0 in 0/61
Lambda= 0.038261
statistics sampled from 28429 (29694) to 28429 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.348), width: 16
Scan time: 17.950
The best scores are: opt bits E(85289)
XP_005273381 (OMIM: 603412) PREDICTED: serine/thre (1732) 6296 366.1 1.5e-99
XP_016858067 (OMIM: 603412) PREDICTED: serine/thre (1767) 6296 366.1 1.5e-99
XP_005273377 (OMIM: 603412) PREDICTED: serine/thre (1794) 6296 366.1 1.6e-99
XP_005273375 (OMIM: 603412) PREDICTED: serine/thre (1829) 6296 366.2 1.6e-99
XP_016858071 (OMIM: 603412) PREDICTED: serine/thre (1589) 6289 365.7 1.9e-99
NP_003598 (OMIM: 603412) serine/threonine-protein (1719) 6289 365.7 2e-99
XP_005273379 (OMIM: 603412) PREDICTED: serine/thre (1754) 6289 365.7 2e-99
XP_005273378 (OMIM: 603412) PREDICTED: serine/thre (1781) 6289 365.8 2e-99
XP_011542610 (OMIM: 603412) PREDICTED: serine/thre (1783) 6289 365.8 2e-99
XP_006711898 (OMIM: 603412) PREDICTED: serine/thre (1797) 6289 365.8 2e-99
XP_011542609 (OMIM: 603412) PREDICTED: serine/thre (1810) 6289 365.8 2e-99
XP_006711897 (OMIM: 603412) PREDICTED: serine/thre (1816) 6289 365.8 2.1e-99
XP_005273374 (OMIM: 603412) PREDICTED: serine/thre (1832) 6289 365.8 2.1e-99
XP_011542608 (OMIM: 603412) PREDICTED: serine/thre (1845) 6289 365.8 2.1e-99
XP_016858070 (OMIM: 603412) PREDICTED: serine/thre (1712) 5602 327.8 5.2e-88
XP_016858068 (OMIM: 603412) PREDICTED: serine/thre (1741) 5602 327.8 5.2e-88
XP_016858069 (OMIM: 603412) PREDICTED: serine/thre (1741) 5602 327.8 5.2e-88
NP_055641 (OMIM: 603412) serine/threonine-protein (1638) 5004 294.8 4.3e-78
XP_011535689 (OMIM: 614062) PREDICTED: serine/thre (1460) 4383 260.4 8.4e-68
XP_005268287 (OMIM: 614062) PREDICTED: serine/thre (1490) 4383 260.4 8.5e-68
XP_005268286 (OMIM: 614062) PREDICTED: serine/thre (1685) 4383 260.5 9.2e-68
XP_005268285 (OMIM: 614062) PREDICTED: serine/thre (1702) 4383 260.5 9.2e-68
NP_006026 (OMIM: 614062) serine/threonine-protein (1711) 4383 260.5 9.3e-68
XP_005268284 (OMIM: 614062) PREDICTED: serine/thre (1728) 4383 260.5 9.3e-68
XP_011542611 (OMIM: 603412) PREDICTED: serine/thre (1764) 4135 246.9 1.2e-63
XP_016873487 (OMIM: 613991) PREDICTED: serine/thre (1081) 2148 136.9 9.7e-31
XP_011543463 (OMIM: 613991) PREDICTED: serine/thre (1135) 2148 136.9 9.9e-31
XP_016873486 (OMIM: 613991) PREDICTED: serine/thre (1139) 2148 136.9 1e-30
XP_011543461 (OMIM: 613991) PREDICTED: serine/thre (1481) 2148 137.1 1.2e-30
XP_011543460 (OMIM: 613991) PREDICTED: serine/thre (1495) 2148 137.1 1.2e-30
XP_011543459 (OMIM: 613991) PREDICTED: serine/thre (1530) 2148 137.1 1.2e-30
NP_059995 (OMIM: 613991) serine/threonine-protein (1551) 2148 137.1 1.2e-30
XP_011543457 (OMIM: 613991) PREDICTED: serine/thre (1569) 2148 137.1 1.2e-30
XP_016873485 (OMIM: 613991) PREDICTED: serine/thre (1568) 2146 137.0 1.3e-30
XP_011543458 (OMIM: 613991) PREDICTED: serine/thre (1562) 2134 136.3 2.1e-30
XP_016873488 (OMIM: 613991) PREDICTED: serine/thre ( 865) 1957 126.2 1.3e-27
XP_011543462 (OMIM: 613991) PREDICTED: serine/thre (1471) 1798 117.7 7.6e-25
NP_004400 (OMIM: 160900,605377) myotonin-protein k ( 629) 1726 113.3 7.2e-24
NP_001275695 (OMIM: 160900,605377) myotonin-protei ( 530) 1712 112.4 1.1e-23
NP_001075029 (OMIM: 160900,605377) myotonin-protei ( 624) 1712 112.5 1.2e-23
NP_001075031 (OMIM: 160900,605377) myotonin-protei ( 625) 1712 112.5 1.2e-23
NP_001075032 (OMIM: 160900,605377) myotonin-protei ( 639) 1594 106.0 1.1e-21
NP_001275693 (OMIM: 160900,605377) myotonin-protei ( 655) 1594 106.0 1.1e-21
NP_005397 (OMIM: 601702) rho-associated protein ki (1354) 1528 102.8 2.2e-20
NP_004841 (OMIM: 604002) rho-associated protein ki (1388) 1519 102.3 3.2e-20
XP_016860867 (OMIM: 604002) PREDICTED: rho-associa (1404) 1519 102.3 3.2e-20
XP_005246247 (OMIM: 604002) PREDICTED: rho-associa (1417) 1519 102.3 3.2e-20
NP_001275694 (OMIM: 160900,605377) myotonin-protei ( 541) 1429 96.8 5.6e-19
NP_001308572 (OMIM: 604002) rho-associated protein (1302) 1425 97.1 1.1e-18
XP_011508719 (OMIM: 604002) PREDICTED: rho-associa (1331) 1425 97.1 1.1e-18
>>XP_005273381 (OMIM: 603412) PREDICTED: serine/threonin (1732 aa)
initn: 6296 init1: 6296 opt: 6296 Z-score: 1908.1 bits: 366.1 E(85289): 1.5e-99
Smith-Waterman score: 10995; 97.6% identity (97.6% similar) in 1723 aa overlap (1-1682:1-1723)
10 20 30 40 50 60
pF1KB3 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
910 920 930 940 950 960
970
pF1KB3 TDALDQFER-----------------------------------------KTHQFFVKSF
::::::::: ::::::::::
XP_005 TDALDQFERSPSCTPASKGRRTVDSTPLSVHTPTLRKKGCPGSTGFPPKRKTHQFFVKSF
970 980 990 1000 1010 1020
980 990 1000 1010 1020 1030
pF1KB3 TTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKG
1030 1040 1050 1060 1070 1080
1040 1050 1060 1070 1080 1090
pF1KB3 IGTAYEGHVRIPKPAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGTAYEGHVRIPKPAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEE
1090 1100 1110 1120 1130 1140
1100 1110 1120 1130 1140 1150
pF1KB3 FSVSSVLASDVIHASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSVSSVLASDVIHASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELH
1150 1160 1170 1180 1190 1200
1160 1170 1180 1190 1200 1210
pF1KB3 KILKKNKFRDRSVYVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KILKKNKFRDRSVYVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEII
1210 1220 1230 1240 1250 1260
1220 1230 1240 1250 1260 1270
pF1KB3 RVGDNKKIHQIELIPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVGDNKKIHQIELIPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSG
1270 1280 1290 1300 1310 1320
1280 1290 1300 1310 1320 1330
pF1KB3 KVRHGALTCLCVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVRHGALTCLCVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGF
1330 1340 1350 1360 1370 1380
1340 1350 1360 1370 1380 1390
pF1KB3 LRYPLNGEGNPYSMLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRYPLNGEGNPYSMLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRR
1390 1400 1410 1420 1430 1440
1400 1410 1420 1430 1440 1450
pF1KB3 SRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNL
1450 1460 1470 1480 1490 1500
1460 1470 1480 1490 1500 1510
pF1KB3 LGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREM
1510 1520 1530 1540 1550 1560
1520 1530 1540 1550 1560 1570
pF1KB3 LRDPEMRNKLISNPTNFNHIAHMGPGDGIQILKDLPMNPRPQESRTVFSGSVSIPSITKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRDPEMRNKLISNPTNFNHIAHMGPGDGIQILKDLPMNPRPQESRTVFSGSVSIPSITKS
1570 1580 1590 1600 1610 1620
1580 1590 1600 1610 1620 1630
pF1KB3 RPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSD
1630 1640 1650 1660 1670 1680
1640 1650 1660 1670 1680 1690
pF1KB3 APARDFDGEDSDSPRHSTASNSSNLSSPPSPVSPRKTKSLSLESTDRGSWDP
:::::::::::::::::::::::::::::::.:::::::::::
XP_005 APARDFDGEDSDSPRHSTASNSSNLSSPPSPASPRKTKSLSLESTDRGSWDP
1690 1700 1710 1720 1730
>>XP_016858067 (OMIM: 603412) PREDICTED: serine/threonin (1767 aa)
initn: 6296 init1: 6296 opt: 6296 Z-score: 1908.0 bits: 366.1 E(85289): 1.5e-99
Smith-Waterman score: 10707; 95.6% identity (95.6% similar) in 1723 aa overlap (1-1647:1-1723)
10 20 30 40 50 60
pF1KB3 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
910 920 930 940 950 960
pF1KB3 TDALDQFER---------------------------------------------------
:::::::::
XP_016 TDALDQFERSPSCTPASKGRRTDPVENTYVWNPSVKFHIQSRSTSPSTSSEAEPVKTVDS
970 980 990 1000 1010 1020
970 980 990 1000
pF1KB3 -------------------------KTHQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEV
:::::::::::::::::::::::::::::::::::
XP_016 TPLSVHTPTLRKKGCPGSTGFPPKRKTHQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEV
1030 1040 1050 1060 1070 1080
1010 1020 1030 1040 1050 1060
pF1KB3 CGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPKPAGVKKGWQRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPKPAGVKKGWQRAL
1090 1100 1110 1120 1130 1140
1070 1080 1090 1100 1110 1120
pF1KB3 AIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIHASRKDIPCIFRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIHASRKDIPCIFRV
1150 1160 1170 1180 1190 1200
1130 1140 1150 1160 1170 1180
pF1KB3 TASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSVYVPKEAYDSTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSVYVPKEAYDSTLP
1210 1220 1230 1240 1250 1260
1190 1200 1210 1220 1230 1240
pF1KB3 LIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIELIPNDQLVAVISG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIELIPNDQLVAVISG
1270 1280 1290 1300 1310 1320
1250 1260 1270 1280 1290 1300
pF1KB3 RNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVAMKRQVLCYELFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVAMKRQVLCYELFQ
1330 1340 1350 1360 1370 1380
1310 1320 1330 1340 1350 1360
pF1KB3 SKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYSMLHSNDHTLSFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYSMLHSNDHTLSFI
1390 1400 1410 1420 1430 1440
1370 1380 1390 1400 1410 1420
pF1KB3 AHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVY
1450 1460 1470 1480 1490 1500
1430 1440 1450 1460 1470 1480
pF1KB3 SENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKNKMAEGDELVVPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKNKMAEGDELVVPE
1510 1520 1530 1540 1550 1560
1490 1500 1510 1520 1530 1540
pF1KB3 TSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISNPTNFNHIAHMGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISNPTNFNHIAHMGP
1570 1580 1590 1600 1610 1620
1550 1560 1570 1580 1590 1600
pF1KB3 GDGIQILKDLPMNPRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSGLSARSSAQNGSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDGIQILKDLPMNPRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSGLSARSSAQNGSA
1630 1640 1650 1660 1670 1680
1610 1620 1630 1640 1650 1660
pF1KB3 LKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDSPRHSTASNSSNL
:::::::::::::::::::::::::::::::::::::::::::
XP_016 LKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDSPRHSTASNSSNL
1690 1700 1710 1720 1730 1740
1670 1680 1690
pF1KB3 SSPPSPVSPRKTKSLSLESTDRGSWDP
XP_016 SSPPSPASPRKTKSLSLESTDRGSWDP
1750 1760
>>XP_005273377 (OMIM: 603412) PREDICTED: serine/threonin (1794 aa)
initn: 10286 init1: 6296 opt: 6296 Z-score: 1907.9 bits: 366.1 E(85289): 1.6e-99
Smith-Waterman score: 10454; 94.0% identity (94.0% similar) in 1723 aa overlap (1-1620:1-1723)
10 20 30 40 50 60
pF1KB3 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
910 920 930 940 950 960
970
pF1KB3 TDALDQFER-----------------------------------------KTHQFFVKSF
::::::::: ::::::::::
XP_005 TDALDQFERSPSCTPASKGRRTVDSTPLSVHTPTLRKKGCPGSTGFPPKRKTHQFFVKSF
970 980 990 1000 1010 1020
980 990 1000 1010 1020 1030
pF1KB3 TTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKG
1030 1040 1050 1060 1070 1080
1040 1050 1060 1070 1080 1090
pF1KB3 IGTAYEGHVRIPKPAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGTAYEGHVRIPKPAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEE
1090 1100 1110 1120 1130 1140
1100 1110 1120 1130 1140 1150
pF1KB3 FSVSSVLASDVIHASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSVSSVLASDVIHASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELH
1150 1160 1170 1180 1190 1200
1160 1170 1180 1190 1200 1210
pF1KB3 KILKKNKFRDRSVYVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KILKKNKFRDRSVYVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEII
1210 1220 1230 1240 1250 1260
1220 1230 1240 1250 1260 1270
pF1KB3 RVGDNKKIHQIELIPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVGDNKKIHQIELIPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSG
1270 1280 1290 1300 1310 1320
1280 1290 1300 1310 1320 1330
pF1KB3 KVRHGALTCLCVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVRHGALTCLCVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGF
1330 1340 1350 1360 1370 1380
1340 1350 1360 1370 1380 1390
pF1KB3 LRYPLNGEGNPYSMLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRYPLNGEGNPYSMLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRR
1390 1400 1410 1420 1430 1440
1400 1410 1420 1430 1440 1450
pF1KB3 SRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNL
1450 1460 1470 1480 1490 1500
1460 1470 1480 1490 1500 1510
pF1KB3 LGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREM
1510 1520 1530 1540 1550 1560
1520 1530 1540 1550
pF1KB3 LRDPEMRNKLISNPTNFNHIAHMGPGDGIQILKDLPM-----------------------
:::::::::::::::::::::::::::::::::::::
XP_005 LRDPEMRNKLISNPTNFNHIAHMGPGDGIQILKDLPMPGFPYPSPHHHSGLISSPINFEH
1570 1580 1590 1600 1610 1620
1560 1570
pF1KB3 ---------------------------------------NPRPQESRTVFSGSVSIPSIT
:::::::::::::::::::::
XP_005 IYHMTVNSAEKFLSPDSINPEYSPSLRSVPGTPSFMTLRNPRPQESRTVFSGSVSIPSIT
1630 1640 1650 1660 1670 1680
1580 1590 1600 1610 1620 1630
pF1KB3 KSRPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQG
:::::::::::::::::::::::::::::::::::::::::::
XP_005 KSRPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQG
1690 1700 1710 1720 1730 1740
1640 1650 1660 1670 1680 1690
pF1KB3 SDAPARDFDGEDSDSPRHSTASNSSNLSSPPSPVSPRKTKSLSLESTDRGSWDP
XP_005 SDAPARDFDGEDSDSPRHSTASNSSNLSSPPSPASPRKTKSLSLESTDRGSWDP
1750 1760 1770 1780 1790
>>XP_005273375 (OMIM: 603412) PREDICTED: serine/threonin (1829 aa)
initn: 10286 init1: 6296 opt: 6296 Z-score: 1907.8 bits: 366.2 E(85289): 1.6e-99
Smith-Waterman score: 10169; 92.0% identity (92.0% similar) in 1723 aa overlap (1-1585:1-1723)
10 20 30 40 50 60
pF1KB3 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
910 920 930 940 950 960
pF1KB3 TDALDQFER---------------------------------------------------
:::::::::
XP_005 TDALDQFERSPSCTPASKGRRTDPVENTYVWNPSVKFHIQSRSTSPSTSSEAEPVKTVDS
970 980 990 1000 1010 1020
970 980 990 1000
pF1KB3 -------------------------KTHQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEV
:::::::::::::::::::::::::::::::::::
XP_005 TPLSVHTPTLRKKGCPGSTGFPPKRKTHQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEV
1030 1040 1050 1060 1070 1080
1010 1020 1030 1040 1050 1060
pF1KB3 CGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPKPAGVKKGWQRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPKPAGVKKGWQRAL
1090 1100 1110 1120 1130 1140
1070 1080 1090 1100 1110 1120
pF1KB3 AIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIHASRKDIPCIFRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIHASRKDIPCIFRV
1150 1160 1170 1180 1190 1200
1130 1140 1150 1160 1170 1180
pF1KB3 TASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSVYVPKEAYDSTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSVYVPKEAYDSTLP
1210 1220 1230 1240 1250 1260
1190 1200 1210 1220 1230 1240
pF1KB3 LIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIELIPNDQLVAVISG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIELIPNDQLVAVISG
1270 1280 1290 1300 1310 1320
1250 1260 1270 1280 1290 1300
pF1KB3 RNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVAMKRQVLCYELFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVAMKRQVLCYELFQ
1330 1340 1350 1360 1370 1380
1310 1320 1330 1340 1350 1360
pF1KB3 SKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYSMLHSNDHTLSFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYSMLHSNDHTLSFI
1390 1400 1410 1420 1430 1440
1370 1380 1390 1400 1410 1420
pF1KB3 AHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVY
1450 1460 1470 1480 1490 1500
1430 1440 1450 1460 1470 1480
pF1KB3 SENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKNKMAEGDELVVPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKNKMAEGDELVVPE
1510 1520 1530 1540 1550 1560
1490 1500 1510 1520 1530 1540
pF1KB3 TSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISNPTNFNHIAHMGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISNPTNFNHIAHMGP
1570 1580 1590 1600 1610 1620
1550
pF1KB3 GDGIQILKDLPM------------------------------------------------
::::::::::::
XP_005 GDGIQILKDLPMPGFPYPSPHHHSGLISSPINFEHIYHMTVNSAEKFLSPDSINPEYSPS
1630 1640 1650 1660 1670 1680
1560 1570 1580 1590 1600
pF1KB3 --------------NPRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSGLSARSSAQNG
:::::::::::::::::::::::::::::
XP_005 LRSVPGTPSFMTLRNPRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSGLSARSSAQNG
1690 1700 1710 1720 1730 1740
1610 1620 1630 1640 1650 1660
pF1KB3 SALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDSPRHSTASNSS
XP_005 SALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDSPRHSTASNSS
1750 1760 1770 1780 1790 1800
>--
initn: 693 init1: 693 opt: 693 Z-score: 236.4 bits: 56.9 E(85289): 2e-06
Smith-Waterman score: 693; 99.1% identity (100.0% similar) in 106 aa overlap (1586-1691:1724-1829)
1560 1570 1580 1590 1600 1610
pF1KB3 MNPRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYS
::::::::::::::::::::::::::::::
XP_005 RNPRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYS
1700 1710 1720 1730 1740 1750
1620 1630 1640 1650 1660 1670
pF1KB3 AKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDSPRHSTASNSSNLSSPPSPVSPRK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_005 AKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDSPRHSTASNSSNLSSPPSPASPRK
1760 1770 1780 1790 1800 1810
1680 1690
pF1KB3 TKSLSLESTDRGSWDP
::::::::::::::::
XP_005 TKSLSLESTDRGSWDP
1820
>>XP_016858071 (OMIM: 603412) PREDICTED: serine/threonin (1589 aa)
initn: 10261 init1: 6289 opt: 6289 Z-score: 1906.4 bits: 365.7 E(85289): 1.9e-99
Smith-Waterman score: 10209; 98.0% identity (98.2% similar) in 1587 aa overlap (1-1559:1-1587)
10 20 30 40 50 60
pF1KB3 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
910 920 930 940 950 960
970 980 990
pF1KB3 TDALDQFE----------------------------RKTHQFFVKSFTTPTKCHQCTSLM
:::::::: ::::::::::::::::::::::::
XP_016 TDALDQFETVDSTPLSVHTPTLRKKGCPGSTGFPPKRKTHQFFVKSFTTPTKCHQCTSLM
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KB3 VGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPK
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KB3 PAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIH
1090 1100 1110 1120 1130 1140
1120 1130 1140 1150 1160 1170
pF1KB3 ASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSV
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210 1220 1230
pF1KB3 YVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIEL
1210 1220 1230 1240 1250 1260
1240 1250 1260 1270 1280 1290
pF1KB3 IPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVA
1270 1280 1290 1300 1310 1320
1300 1310 1320 1330 1340 1350
pF1KB3 MKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYS
1330 1340 1350 1360 1370 1380
1360 1370 1380 1390 1400 1410
pF1KB3 MLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPS
1390 1400 1410 1420 1430 1440
1420 1430 1440 1450 1460 1470
pF1KB3 SCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKN
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KB3 KMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISN
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KB3 PTNFNHIAHMGPGDGIQILKDLPMNPRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSG
::::::::::::::::::::::::. .
XP_016 PTNFNHIAHMGPGDGIQILKDLPMDKKLV
1570 1580
>>NP_003598 (OMIM: 603412) serine/threonine-protein kina (1719 aa)
initn: 6289 init1: 6289 opt: 6289 Z-score: 1906.0 bits: 365.7 E(85289): 2e-99
Smith-Waterman score: 11092; 98.3% identity (98.4% similar) in 1719 aa overlap (1-1691:1-1719)
10 20 30 40 50 60
pF1KB3 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
910 920 930 940 950 960
970 980 990
pF1KB3 TDALDQFE----------------------------RKTHQFFVKSFTTPTKCHQCTSLM
:::::::: ::::::::::::::::::::::::
NP_003 TDALDQFETVDSTPLSVHTPTLRKKGCPGSTGFPPKRKTHQFFVKSFTTPTKCHQCTSLM
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KB3 VGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPK
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KB3 PAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIH
1090 1100 1110 1120 1130 1140
1120 1130 1140 1150 1160 1170
pF1KB3 ASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSV
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210 1220 1230
pF1KB3 YVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIEL
1210 1220 1230 1240 1250 1260
1240 1250 1260 1270 1280 1290
pF1KB3 IPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVA
1270 1280 1290 1300 1310 1320
1300 1310 1320 1330 1340 1350
pF1KB3 MKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYS
1330 1340 1350 1360 1370 1380
1360 1370 1380 1390 1400 1410
pF1KB3 MLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPS
1390 1400 1410 1420 1430 1440
1420 1430 1440 1450 1460 1470
pF1KB3 SCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKN
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KB3 KMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISN
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KB3 PTNFNHIAHMGPGDGIQILKDLPMNPRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PTNFNHIAHMGPGDGIQILKDLPMNPRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSG
1570 1580 1590 1600 1610 1620
1600 1610 1620 1630 1640 1650
pF1KB3 LSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDS
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690
pF1KB3 PRHSTASNSSNLSSPPSPVSPRKTKSLSLESTDRGSWDP
::::::::::::::::::.::::::::::::::::::::
NP_003 PRHSTASNSSNLSSPPSPASPRKTKSLSLESTDRGSWDP
1690 1700 1710
>>XP_005273379 (OMIM: 603412) PREDICTED: serine/threonin (1754 aa)
initn: 6289 init1: 6289 opt: 6289 Z-score: 1906.0 bits: 365.7 E(85289): 2e-99
Smith-Waterman score: 10819; 96.3% identity (96.3% similar) in 1723 aa overlap (1-1660:1-1723)
10 20 30 40 50 60
pF1KB3 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
910 920 930 940 950 960
pF1KB3 TDALDQFE----------------------------------------------------
::::::::
XP_005 TDALDQFETDPVENTYVWNPSVKFHIQSRSTSPSTSSEAEPVKTVDSTPLSVHTPTLRKK
970 980 990 1000 1010 1020
970 980 990 1000 1010
pF1KB3 -----------RKTHQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKA
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GCPGSTGFPPKRKTHQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKA
1030 1040 1050 1060 1070 1080
1020 1030 1040 1050 1060 1070
pF1KB3 PTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPKPAGVKKGWQRALAIVCDFKLFLYDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPKPAGVKKGWQRALAIVCDFKLFLYDI
1090 1100 1110 1120 1130 1140
1080 1090 1100 1110 1120 1130
pF1KB3 AEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIHASRKDIPCIFRVTASQLSASNNKCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIHASRKDIPCIFRVTASQLSASNNKCS
1150 1160 1170 1180 1190 1200
1140 1150 1160 1170 1180 1190
pF1KB3 ILMLADTENEKNKWVGVLSELHKILKKNKFRDRSVYVPKEAYDSTLPLIKTTQAAAIIDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILMLADTENEKNKWVGVLSELHKILKKNKFRDRSVYVPKEAYDSTLPLIKTTQAAAIIDH
1210 1220 1230 1240 1250 1260
1200 1210 1220 1230 1240 1250
pF1KB3 ERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIELIPNDQLVAVISGRNRHVRLFPMSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIELIPNDQLVAVISGRNRHVRLFPMSAL
1270 1280 1290 1300 1310 1320
1260 1270 1280 1290 1300 1310
pF1KB3 DGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVAMKRQVLCYELFQSKTRHRKFKEIQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVAMKRQVLCYELFQSKTRHRKFKEIQV
1330 1340 1350 1360 1370 1380
1320 1330 1340 1350 1360 1370
pF1KB3 PYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYSMLHSNDHTLSFIAHQPMDAICAVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYSMLHSNDHTLSFIAHQPMDAICAVEI
1390 1400 1410 1420 1430 1440
1380 1390 1400 1410 1420 1430
pF1KB3 SSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSM
1450 1460 1470 1480 1490 1500
1440 1450 1460 1470 1480 1490
pF1KB3 EWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNI
1510 1520 1530 1540 1550 1560
1500 1510 1520 1530 1540 1550
pF1KB3 NNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISNPTNFNHIAHMGPGDGIQILKDLPMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISNPTNFNHIAHMGPGDGIQILKDLPMN
1570 1580 1590 1600 1610 1620
1560 1570 1580 1590 1600 1610
pF1KB3 PRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYSAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYSAK
1630 1640 1650 1660 1670 1680
1620 1630 1640 1650 1660 1670
pF1KB3 RQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDSPRHSTASNSSNLSSPPSPVSPRKTK
:::::::::::::::::::::::::::::::::::::::::::
XP_005 RQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDSPRHSTASNSSNLSSPPSPASPRKTK
1690 1700 1710 1720 1730 1740
1680 1690
pF1KB3 SLSLESTDRGSWDP
XP_005 SLSLESTDRGSWDP
1750
>>XP_005273378 (OMIM: 603412) PREDICTED: serine/threonin (1781 aa)
initn: 10279 init1: 6289 opt: 6289 Z-score: 1905.9 bits: 365.8 E(85289): 2e-99
Smith-Waterman score: 10567; 94.8% identity (94.8% similar) in 1723 aa overlap (1-1633:1-1723)
10 20 30 40 50 60
pF1KB3 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
910 920 930 940 950 960
970 980 990
pF1KB3 TDALDQFE----------------------------RKTHQFFVKSFTTPTKCHQCTSLM
:::::::: ::::::::::::::::::::::::
XP_005 TDALDQFETVDSTPLSVHTPTLRKKGCPGSTGFPPKRKTHQFFVKSFTTPTKCHQCTSLM
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KB3 VGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPK
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KB3 PAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIH
1090 1100 1110 1120 1130 1140
1120 1130 1140 1150 1160 1170
pF1KB3 ASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSV
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210 1220 1230
pF1KB3 YVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIEL
1210 1220 1230 1240 1250 1260
1240 1250 1260 1270 1280 1290
pF1KB3 IPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVA
1270 1280 1290 1300 1310 1320
1300 1310 1320 1330 1340 1350
pF1KB3 MKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYS
1330 1340 1350 1360 1370 1380
1360 1370 1380 1390 1400 1410
pF1KB3 MLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPS
1390 1400 1410 1420 1430 1440
1420 1430 1440 1450 1460 1470
pF1KB3 SCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKN
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KB3 KMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISN
1510 1520 1530 1540 1550 1560
1540 1550
pF1KB3 PTNFNHIAHMGPGDGIQILKDLPM------------------------------------
::::::::::::::::::::::::
XP_005 PTNFNHIAHMGPGDGIQILKDLPMPGFPYPSPHHHSGLISSPINFEHIYHMTVNSAEKFL
1570 1580 1590 1600 1610 1620
1560 1570 1580 1590
pF1KB3 --------------------------NPRPQESRTVFSGSVSIPSITKSRPEPGRSMSAS
::::::::::::::::::::::::::::::::::
XP_005 SPDSINPEYSPSLRSVPGTPSFMTLRNPRPQESRTVFSGSVSIPSITKSRPEPGRSMSAS
1630 1640 1650 1660 1670 1680
1600 1610 1620 1630 1640 1650
pF1KB3 SGLSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDS
:::::::::::::::::::::::::::::::::::::::::::
XP_005 SGLSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDS
1690 1700 1710 1720 1730 1740
1660 1670 1680 1690
pF1KB3 DSPRHSTASNSSNLSSPPSPVSPRKTKSLSLESTDRGSWDP
XP_005 DSPRHSTASNSSNLSSPPSPASPRKTKSLSLESTDRGSWDP
1750 1760 1770 1780
>>XP_011542610 (OMIM: 603412) PREDICTED: serine/threonin (1783 aa)
initn: 6289 init1: 6289 opt: 6289 Z-score: 1905.9 bits: 365.8 E(85289): 2e-99
Smith-Waterman score: 10557; 94.7% identity (94.7% similar) in 1723 aa overlap (1-1631:1-1723)
10 20 30 40 50 60
pF1KB3 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
910 920 930 940 950 960
pF1KB3 TDALDQFE----------------------------------------------------
::::::::
XP_011 TDALDQFEDSFSSSSSSLIDFLDDRSPSCTPASKGRRTDPVENTYVWNPSVKFHIQSRST
970 980 990 1000 1010 1020
970 980
pF1KB3 ----------------------------------------RKTHQFFVKSFTTPTKCHQC
::::::::::::::::::::
XP_011 SPSTSSEAEPVKTVDSTPLSVHTPTLRKKGCPGSTGFPPKRKTHQFFVKSFTTPTKCHQC
1030 1040 1050 1060 1070 1080
990 1000 1010 1020 1030 1040
pF1KB3 TSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHV
1090 1100 1110 1120 1130 1140
1050 1060 1070 1080 1090 1100
pF1KB3 RIPKPAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIPKPAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLAS
1150 1160 1170 1180 1190 1200
1110 1120 1130 1140 1150 1160
pF1KB3 DVIHASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVIHASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFR
1210 1220 1230 1240 1250 1260
1170 1180 1190 1200 1210 1220
pF1KB3 DRSVYVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRSVYVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIH
1270 1280 1290 1300 1310 1320
1230 1240 1250 1260 1270 1280
pF1KB3 QIELIPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIELIPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTC
1330 1340 1350 1360 1370 1380
1290 1300 1310 1320 1330 1340
pF1KB3 LCVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEG
1390 1400 1410 1420 1430 1440
1350 1360 1370 1380 1390 1400
pF1KB3 NPYSMLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPYSMLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWP
1450 1460 1470 1480 1490 1500
1410 1420 1430 1440 1450 1460
pF1KB3 ANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLI
1510 1520 1530 1540 1550 1560
1470 1480 1490 1500 1510 1520
pF1KB3 YFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNK
1570 1580 1590 1600 1610 1620
1530 1540 1550 1560 1570 1580
pF1KB3 LISNPTNFNHIAHMGPGDGIQILKDLPMNPRPQESRTVFSGSVSIPSITKSRPEPGRSMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LISNPTNFNHIAHMGPGDGIQILKDLPMNPRPQESRTVFSGSVSIPSITKSRPEPGRSMS
1630 1640 1650 1660 1670 1680
1590 1600 1610 1620 1630 1640
pF1KB3 ASSGLSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGE
:::::::::::::::::::::::::::::::::::::::::::
XP_011 ASSGLSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGE
1690 1700 1710 1720 1730 1740
1650 1660 1670 1680 1690
pF1KB3 DSDSPRHSTASNSSNLSSPPSPVSPRKTKSLSLESTDRGSWDP
XP_011 DSDSPRHSTASNSSNLSSPPSPASPRKTKSLSLESTDRGSWDP
1750 1760 1770 1780
>>XP_006711898 (OMIM: 603412) PREDICTED: serine/threonin (1797 aa)
initn: 10279 init1: 6289 opt: 6289 Z-score: 1905.8 bits: 365.8 E(85289): 2e-99
Smith-Waterman score: 10424; 93.8% identity (93.8% similar) in 1723 aa overlap (1-1617:1-1723)
10 20 30 40 50 60
pF1KB3 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
910 920 930 940 950 960
970
pF1KB3 TDALDQFE--------------------------------------------RKTHQFFV
:::::::: ::::::::
XP_006 TDALDQFEDSFSSSSSSLIDFLDDTVDSTPLSVHTPTLRKKGCPGSTGFPPKRKTHQFFV
970 980 990 1000 1010 1020
980 990 1000 1010 1020 1030
pF1KB3 KSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDP
1030 1040 1050 1060 1070 1080
1040 1050 1060 1070 1080 1090
pF1KB3 QKGIGTAYEGHVRIPKPAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QKGIGTAYEGHVRIPKPAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMR
1090 1100 1110 1120 1130 1140
1100 1110 1120 1130 1140 1150
pF1KB3 DEEFSVSSVLASDVIHASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DEEFSVSSVLASDVIHASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLS
1150 1160 1170 1180 1190 1200
1160 1170 1180 1190 1200 1210
pF1KB3 ELHKILKKNKFRDRSVYVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELHKILKKNKFRDRSVYVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKD
1210 1220 1230 1240 1250 1260
1220 1230 1240 1250 1260 1270
pF1KB3 EIIRVGDNKKIHQIELIPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EIIRVGDNKKIHQIELIPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTV
1270 1280 1290 1300 1310 1320
1280 1290 1300 1310 1320 1330
pF1KB3 TSGKVRHGALTCLCVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TSGKVRHGALTCLCVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQ
1330 1340 1350 1360 1370 1380
1340 1350 1360 1370 1380 1390
pF1KB3 SGFLRYPLNGEGNPYSMLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGFLRYPLNGEGNPYSMLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQ
1390 1400 1410 1420 1430 1440
1400 1410 1420 1430 1440 1450
pF1KB3 GRRSRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GRRSRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGS
1450 1460 1470 1480 1490 1500
1460 1470 1480 1490 1500 1510
pF1KB3 LNLLGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LNLLGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQR
1510 1520 1530 1540 1550 1560
1520 1530 1540 1550
pF1KB3 REMLRDPEMRNKLISNPTNFNHIAHMGPGDGIQILKDLPM--------------------
::::::::::::::::::::::::::::::::::::::::
XP_006 REMLRDPEMRNKLISNPTNFNHIAHMGPGDGIQILKDLPMPGFPYPSPHHHSGLISSPIN
1570 1580 1590 1600 1610 1620
1560 1570
pF1KB3 ------------------------------------------NPRPQESRTVFSGSVSIP
::::::::::::::::::
XP_006 FEHIYHMTVNSAEKFLSPDSINPEYSPSLRSVPGTPSFMTLRNPRPQESRTVFSGSVSIP
1630 1640 1650 1660 1670 1680
1580 1590 1600 1610 1620 1630
pF1KB3 SITKSRPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGM
:::::::::::::::::::::::::::::::::::::::::::
XP_006 SITKSRPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGM
1690 1700 1710 1720 1730 1740
1640 1650 1660 1670 1680 1690
pF1KB3 DQGSDAPARDFDGEDSDSPRHSTASNSSNLSSPPSPVSPRKTKSLSLESTDRGSWDP
XP_006 DQGSDAPARDFDGEDSDSPRHSTASNSSNLSSPPSPASPRKTKSLSLESTDRGSWDP
1750 1760 1770 1780 1790
1691 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 13:01:41 2016 done: Thu Nov 3 13:01:43 2016
Total Scan time: 17.950 Total Display time: 1.070
Function used was FASTA [36.3.4 Apr, 2011]