Result of FASTA (omim) for
pF1KB3129
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3129, 239 aa
1>>>pF1KB3129 239 - 239 aa - 239 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.8297+/-0.000337; mu= 0.0412+/- 0.021
mean_var=213.5536+/-43.576, 0's: 0 Z-trim(122.3): 36 B-trim: 325 in 1/60
Lambda= 0.087765
statistics sampled from 40266 (40302) to 40266 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.785), E-opt: 0.2 (0.473), width: 16
Scan time: 7.390
The best scores are: opt bits E(85289)
NP_000624 (OMIM: 151430) apoptosis regulator Bcl-2 ( 239) 1659 221.6 9.2e-58
XP_011524437 (OMIM: 151430) PREDICTED: apoptosis r ( 224) 1389 187.4 1.7e-47
XP_016881406 (OMIM: 151430) PREDICTED: apoptosis r ( 198) 1366 184.5 1.2e-46
NP_000648 (OMIM: 151430) apoptosis regulator Bcl-2 ( 205) 1366 184.5 1.2e-46
NP_001304850 (OMIM: 600039) bcl-2-like protein 1 i ( 233) 599 87.4 2.3e-17
NP_001309169 (OMIM: 600039) bcl-2-like protein 1 i ( 233) 599 87.4 2.3e-17
XP_016883482 (OMIM: 600039) PREDICTED: bcl-2-like ( 233) 599 87.4 2.3e-17
NP_001309168 (OMIM: 600039) bcl-2-like protein 1 i ( 233) 599 87.4 2.3e-17
NP_001304848 (OMIM: 600039) bcl-2-like protein 1 i ( 233) 599 87.4 2.3e-17
XP_011527266 (OMIM: 600039) PREDICTED: bcl-2-like ( 233) 599 87.4 2.3e-17
NP_612815 (OMIM: 600039) bcl-2-like protein 1 isof ( 233) 599 87.4 2.3e-17
NP_001309171 (OMIM: 600039) bcl-2-like protein 1 i ( 233) 599 87.4 2.3e-17
NP_001304849 (OMIM: 600039) bcl-2-like protein 1 i ( 233) 599 87.4 2.3e-17
NP_001186768 (OMIM: 601931) bcl-2-like protein 2 [ ( 193) 514 76.6 3.4e-14
NP_004041 (OMIM: 601931) bcl-2-like protein 2 [Hom ( 193) 514 76.6 3.4e-14
XP_011513081 (OMIM: 600516) PREDICTED: bcl-2 homol ( 211) 227 40.3 0.0032
NP_001179 (OMIM: 600516) bcl-2 homologous antagoni ( 211) 227 40.3 0.0032
XP_016882566 (OMIM: 600040) PREDICTED: apoptosis r ( 173) 225 40.0 0.0033
NP_620116 (OMIM: 600040) apoptosis regulator BAX i ( 192) 225 40.0 0.0035
XP_011513082 (OMIM: 600516) PREDICTED: bcl-2 homol ( 152) 218 39.0 0.0055
NP_001182 (OMIM: 600039) bcl-2-like protein 1 isof ( 170) 216 38.8 0.0071
NP_001278360 (OMIM: 600040) apoptosis regulator BA ( 114) 210 37.9 0.0088
>>NP_000624 (OMIM: 151430) apoptosis regulator Bcl-2 alp (239 aa)
initn: 1659 init1: 1659 opt: 1659 Z-score: 1158.0 bits: 221.6 E(85289): 9.2e-58
Smith-Waterman score: 1659; 100.0% identity (100.0% similar) in 239 aa overlap (1-239:1-239)
10 20 30 40 50 60
pF1KB3 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
130 140 150 160 170 180
190 200 210 220 230
pF1KB3 LNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
190 200 210 220 230
>>XP_011524437 (OMIM: 151430) PREDICTED: apoptosis regul (224 aa)
initn: 1423 init1: 1389 opt: 1389 Z-score: 973.6 bits: 187.4 E(85289): 1.7e-47
Smith-Waterman score: 1389; 98.0% identity (99.0% similar) in 203 aa overlap (1-203:1-203)
10 20 30 40 50 60
pF1KB3 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
130 140 150 160 170 180
190 200 210 220 230
pF1KB3 LNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
:::::::::::::::::.: . :
XP_011 LNRHLHTWIQDNGGWDALVLFAGLREFQHGPGNYFLKRNLNAKF
190 200 210 220
>>XP_016881406 (OMIM: 151430) PREDICTED: apoptosis regul (198 aa)
initn: 1366 init1: 1366 opt: 1366 Z-score: 958.6 bits: 184.5 E(85289): 1.2e-46
Smith-Waterman score: 1366; 100.0% identity (100.0% similar) in 195 aa overlap (1-195:1-195)
10 20 30 40 50 60
pF1KB3 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
130 140 150 160 170 180
190 200 210 220 230
pF1KB3 LNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
:::::::::::::::
XP_016 LNRHLHTWIQDNGGWLYM
190
>>NP_000648 (OMIM: 151430) apoptosis regulator Bcl-2 bet (205 aa)
initn: 1366 init1: 1366 opt: 1366 Z-score: 958.4 bits: 184.5 E(85289): 1.2e-46
Smith-Waterman score: 1366; 100.0% identity (100.0% similar) in 195 aa overlap (1-195:1-195)
10 20 30 40 50 60
pF1KB3 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
130 140 150 160 170 180
190 200 210 220 230
pF1KB3 LNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
:::::::::::::::
NP_000 LNRHLHTWIQDNGGWVGALGDVSLG
190 200
>>NP_001304850 (OMIM: 600039) bcl-2-like protein 1 isofo (233 aa)
initn: 606 init1: 524 opt: 599 Z-score: 432.8 bits: 87.4 E(85289): 2.3e-17
Smith-Waterman score: 599; 51.0% identity (72.0% similar) in 200 aa overlap (11-203:5-196)
10 20 30 40 50
pF1KB3 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDA-GDVGAAPPGAAPAP-GIFSSQPGHTPH
:::.:. .. :::::.:: :. .:: . . :: : : . .::
NP_001 MSQSNRELVVDFLSYKLSQKGYSWSQFSDV---EENRTEAPEGTESEM--ETPS
10 20 30 40
60 70 80 90 100 110
pF1KB3 PAASRDPVARTSPLQTPAAPGAAAGP----ALSPVP-PVVHLTLRQAGDDFSRRYRRDFA
: . .: . . ..::. ::.. : .: .:. .::.:::.: :::: :.
NP_001 -AINGNPSWHLA--DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFS
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB3 EMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNI
...::::.:: :: : ::.:::::::::::::::: :::..:::::..::. ::. :
NP_001 DLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRI
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB3 ALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLG
: ::. ::: ::. :::.:::::.::::::
NP_001 AAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLL
170 180 190 200 210 220
>>NP_001309169 (OMIM: 600039) bcl-2-like protein 1 isofo (233 aa)
initn: 606 init1: 524 opt: 599 Z-score: 432.8 bits: 87.4 E(85289): 2.3e-17
Smith-Waterman score: 599; 51.0% identity (72.0% similar) in 200 aa overlap (11-203:5-196)
10 20 30 40 50
pF1KB3 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDA-GDVGAAPPGAAPAP-GIFSSQPGHTPH
:::.:. .. :::::.:: :. .:: . . :: : : . .::
NP_001 MSQSNRELVVDFLSYKLSQKGYSWSQFSDV---EENRTEAPEGTESEM--ETPS
10 20 30 40
60 70 80 90 100 110
pF1KB3 PAASRDPVARTSPLQTPAAPGAAAGP----ALSPVP-PVVHLTLRQAGDDFSRRYRRDFA
: . .: . . ..::. ::.. : .: .:. .::.:::.: :::: :.
NP_001 -AINGNPSWHLA--DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFS
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB3 EMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNI
...::::.:: :: : ::.:::::::::::::::: :::..:::::..::. ::. :
NP_001 DLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRI
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB3 ALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLG
: ::. ::: ::. :::.:::::.::::::
NP_001 AAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLL
170 180 190 200 210 220
>>XP_016883482 (OMIM: 600039) PREDICTED: bcl-2-like prot (233 aa)
initn: 606 init1: 524 opt: 599 Z-score: 432.8 bits: 87.4 E(85289): 2.3e-17
Smith-Waterman score: 599; 51.0% identity (72.0% similar) in 200 aa overlap (11-203:5-196)
10 20 30 40 50
pF1KB3 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDA-GDVGAAPPGAAPAP-GIFSSQPGHTPH
:::.:. .. :::::.:: :. .:: . . :: : : . .::
XP_016 MSQSNRELVVDFLSYKLSQKGYSWSQFSDV---EENRTEAPEGTESEM--ETPS
10 20 30 40
60 70 80 90 100 110
pF1KB3 PAASRDPVARTSPLQTPAAPGAAAGP----ALSPVP-PVVHLTLRQAGDDFSRRYRRDFA
: . .: . . ..::. ::.. : .: .:. .::.:::.: :::: :.
XP_016 -AINGNPSWHLA--DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFS
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB3 EMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNI
...::::.:: :: : ::.:::::::::::::::: :::..:::::..::. ::. :
XP_016 DLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRI
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB3 ALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLG
: ::. ::: ::. :::.:::::.::::::
XP_016 AAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLL
170 180 190 200 210 220
>>NP_001309168 (OMIM: 600039) bcl-2-like protein 1 isofo (233 aa)
initn: 606 init1: 524 opt: 599 Z-score: 432.8 bits: 87.4 E(85289): 2.3e-17
Smith-Waterman score: 599; 51.0% identity (72.0% similar) in 200 aa overlap (11-203:5-196)
10 20 30 40 50
pF1KB3 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDA-GDVGAAPPGAAPAP-GIFSSQPGHTPH
:::.:. .. :::::.:: :. .:: . . :: : : . .::
NP_001 MSQSNRELVVDFLSYKLSQKGYSWSQFSDV---EENRTEAPEGTESEM--ETPS
10 20 30 40
60 70 80 90 100 110
pF1KB3 PAASRDPVARTSPLQTPAAPGAAAGP----ALSPVP-PVVHLTLRQAGDDFSRRYRRDFA
: . .: . . ..::. ::.. : .: .:. .::.:::.: :::: :.
NP_001 -AINGNPSWHLA--DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFS
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB3 EMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNI
...::::.:: :: : ::.:::::::::::::::: :::..:::::..::. ::. :
NP_001 DLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRI
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB3 ALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLG
: ::. ::: ::. :::.:::::.::::::
NP_001 AAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLL
170 180 190 200 210 220
>>NP_001304848 (OMIM: 600039) bcl-2-like protein 1 isofo (233 aa)
initn: 606 init1: 524 opt: 599 Z-score: 432.8 bits: 87.4 E(85289): 2.3e-17
Smith-Waterman score: 599; 51.0% identity (72.0% similar) in 200 aa overlap (11-203:5-196)
10 20 30 40 50
pF1KB3 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDA-GDVGAAPPGAAPAP-GIFSSQPGHTPH
:::.:. .. :::::.:: :. .:: . . :: : : . .::
NP_001 MSQSNRELVVDFLSYKLSQKGYSWSQFSDV---EENRTEAPEGTESEM--ETPS
10 20 30 40
60 70 80 90 100 110
pF1KB3 PAASRDPVARTSPLQTPAAPGAAAGP----ALSPVP-PVVHLTLRQAGDDFSRRYRRDFA
: . .: . . ..::. ::.. : .: .:. .::.:::.: :::: :.
NP_001 -AINGNPSWHLA--DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFS
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB3 EMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNI
...::::.:: :: : ::.:::::::::::::::: :::..:::::..::. ::. :
NP_001 DLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRI
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB3 ALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLG
: ::. ::: ::. :::.:::::.::::::
NP_001 AAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLL
170 180 190 200 210 220
>>XP_011527266 (OMIM: 600039) PREDICTED: bcl-2-like prot (233 aa)
initn: 606 init1: 524 opt: 599 Z-score: 432.8 bits: 87.4 E(85289): 2.3e-17
Smith-Waterman score: 599; 51.0% identity (72.0% similar) in 200 aa overlap (11-203:5-196)
10 20 30 40 50
pF1KB3 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDA-GDVGAAPPGAAPAP-GIFSSQPGHTPH
:::.:. .. :::::.:: :. .:: . . :: : : . .::
XP_011 MSQSNRELVVDFLSYKLSQKGYSWSQFSDV---EENRTEAPEGTESEM--ETPS
10 20 30 40
60 70 80 90 100 110
pF1KB3 PAASRDPVARTSPLQTPAAPGAAAGP----ALSPVP-PVVHLTLRQAGDDFSRRYRRDFA
: . .: . . ..::. ::.. : .: .:. .::.:::.: :::: :.
XP_011 -AINGNPSWHLA--DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFS
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB3 EMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNI
...::::.:: :: : ::.:::::::::::::::: :::..:::::..::. ::. :
XP_011 DLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRI
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB3 ALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLG
: ::. ::: ::. :::.:::::.::::::
XP_011 AAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLL
170 180 190 200 210 220
239 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 12:29:36 2016 done: Thu Nov 3 12:29:37 2016
Total Scan time: 7.390 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]