Result of FASTA (omim) for
pF1KB0487
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0487, 529 aa
1>>>pF1KB0487 529 - 529 aa - 529 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.8846+/-0.000485; mu= 1.9553+/- 0.030
mean_var=197.8108+/-40.328, 0's: 0 Z-trim(115.1): 19 B-trim: 660 in 2/52
Lambda= 0.091190
statistics sampled from 25272 (25287) to 25272 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.622), E-opt: 0.2 (0.296), width: 16
Scan time: 10.290
The best scores are: opt bits E(85289)
NP_057018 (OMIM: 616742) nucleolar protein 58 [Hom ( 529) 3358 454.9 2.8e-127
NP_006383 (OMIM: 614153,614154) nucleolar protein ( 594) 1130 161.8 5.3e-39
XP_006723200 (OMIM: 600138,606419) PREDICTED: U4/U ( 499) 430 69.6 2.4e-11
NP_056444 (OMIM: 600138,606419) U4/U6 small nuclea ( 499) 430 69.6 2.4e-11
>>NP_057018 (OMIM: 616742) nucleolar protein 58 [Homo sa (529 aa)
initn: 3358 init1: 3358 opt: 3358 Z-score: 2406.0 bits: 454.9 E(85289): 2.8e-127
Smith-Waterman score: 3358; 100.0% identity (100.0% similar) in 529 aa overlap (1-529:1-529)
10 20 30 40 50 60
pF1KB0 MLVLFETSVGYAIFKVLNEKKLQEVDSLWKEFETPEKANKIVKLKHFEKFQDTAEALAAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MLVLFETSVGYAIFKVLNEKKLQEVDSLWKEFETPEKANKIVKLKHFEKFQDTAEALAAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 TALMEGKINKQLKKVLKKIVKEAHEPLAVADAKLGGVIKEKLNLSCIHSPVVNELMRGIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 TALMEGKINKQLKKVLKKIVKEAHEPLAVADAKLGGVIKEKLNLSCIHSPVVNELMRGIR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SQMDGLIPGVEPREMAAMCLGLAHSLSRYRLKFSADKVDTMIVQAISLLDDLDKELNNYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SQMDGLIPGVEPREMAAMCLGLAHSLSRYRLKFSADKVDTMIVQAISLLDDLDKELNNYI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 MRCREWYGWHFPELGKIISDNLTYCKCLQKVGDRKNYASAKLSELLPEEVEAEVKAAAEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MRCREWYGWHFPELGKIISDNLTYCKCLQKVGDRKNYASAKLSELLPEEVEAEVKAAAEI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 SMGTEVSEEDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGELVGARLIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SMGTEVSEEDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGELVGARLIA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 HAGSLLNLAKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQTSPKHKGKISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 HAGSLLNLAKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQTSPKHKGKISR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 MLAAKTVLAIRYDAFGEDSSSAMGVENRAKLEARLRTLEDRGIRKISGTGKALAKTEKYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MLAAKTVLAIRYDAFGEDSSSAMGVENRAKLEARLRTLEDRGIRKISGTGKALAKTEKYE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 HKSEVKTYDPSGDSTLPTCSKKRKIEQVDKEDEITEKKAKKAKIKVKVEEEEEEKVAEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 HKSEVKTYDPSGDSTLPTCSKKRKIEQVDKEDEITEKKAKKAKIKVKVEEEEEEKVAEEE
430 440 450 460 470 480
490 500 510 520
pF1KB0 ETSVKKKKKRGKKKHIKEEPLSEEEPCTSTAIASPEKKKKKKKKRENED
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ETSVKKKKKRGKKKHIKEEPLSEEEPCTSTAIASPEKKKKKKKKRENED
490 500 510 520
>>NP_006383 (OMIM: 614153,614154) nucleolar protein 56 [ (594 aa)
initn: 1146 init1: 553 opt: 1130 Z-score: 821.2 bits: 161.8 E(85289): 5.3e-39
Smith-Waterman score: 1147; 39.8% identity (66.6% similar) in 548 aa overlap (3-529:6-546)
10 20 30 40 50
pF1KB0 MLVLFETSVGYAIFKVLNEKKLQEVDSLWKEFETPE----KANKIVKLKHFEKFQDT
:::: .::::. : :...:.. : . : : ..::.: : : ..
NP_006 MVLLHVLFEHAVGYAL---LALKEVEEISLLQPQVEESVLNLGKFHSIVRLVAFCPFASS
10 20 30 40 50
60 70 80 90 100 110
pF1KB0 AEALAAFTALMEGKINKQLKKVLKKIV--KEAHEPLAVADAKLGGVIKEKLNLSCIHSPV
:: .:. :: ....:. .:. . :. . :.:.: :.:..:.:.:. .: . :
NP_006 QVALENANAVSEGVVHEDLRLLLETHLPSKKKKVLLGVGDPKIGAAIQEELGYNCQTGGV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB0 VNELMRGIRSQMDGLIPGVEPREMAAMCLGLAHSLSRYRLKFSADKVDTMIVQAISLLDD
. :..::.: .. .:. :. :::.:: :: ..::....::.::.:.:::::.
NP_006 IAEILRGVRLHFHNLVKGLTDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB0 LDKELNNYIMRCREWYGWHFPELGKIISDNLTYCKCLQKVGDRKNYASAKLSELLPEEVE
:::..:.. :: :::::.::::: :::.:: :::. : .:.:.. :: .: ..
NP_006 LDKDINTFSMRVREWYGYHFPELVKIINDNATYCRLAQFIGNRRELNEDKLEKLEELTMD
180 190 200 210 220 230
240 250 260 270 280
pF1KB0 -AEVKA---AAEISMGTEVSEEDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVT
:..:: :.. ::: ..: :. :: . ..:. .:::: .:. ::...: .::...
NP_006 GAKAKAILDASRSSMGMDISAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB0 VMVGELVGARLIAHAGSLLNLAKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLV
...:: :::::::::::: ::::. ::::::::::::::::::.: .:::::::.:....
NP_006 ALIGEAVGARLIAHAGSLTNLAKYPASTVQILGAEKALFRALKTRGNTPKYGLIFHSTFI
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB0 GQTSPKHKGKISRMLAAKTVLAIRYDAFGEDSSSAMGVENRAKLEARLRTLEDRGI-RKI
:... :.::.:::.:: : .: : : :.: .:..: . : ..: :: : : ::
NP_006 GRAAAKNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKN
360 370 380 390 400 410
410 420 430 440 450
pF1KB0 SGTGK--------ALAKTEKYEHKSEVKTYDPSGD--STLPTCSKKRKIEQVDKEDEITE
. : : :. . .:.: : ..: :.. . .. .:..:
NP_006 LDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSE
420 430 440 450 460 470
460 470 480 490 500 510
pF1KB0 KKAKKAKIKVKVEEEEEEKVAEEEETSVKKKKKRGKKKHIKEEPLSEEEPCTSTAIASPE
: :: : : . : .:. :. : .: :: ::. ::: .: . :. . . :.
NP_006 KPKKKKKQKPQ--EVPQENGMEDPSISFSKPKK--KKSFSKEELMSSDLEETAGSTSIPK
480 490 500 510 520 530
520
pF1KB0 KKKKKKKKRENED
.::. :.. .:
NP_006 RKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQE
540 550 560 570 580 590
>>XP_006723200 (OMIM: 600138,606419) PREDICTED: U4/U6 sm (499 aa)
initn: 405 init1: 327 opt: 430 Z-score: 324.6 bits: 69.6 E(85289): 2.4e-11
Smith-Waterman score: 440; 23.6% identity (61.2% similar) in 381 aa overlap (161-521:92-471)
140 150 160 170 180 190
pF1KB0 EPREMAAMCLGLAHSLSRYRLKFSADKVDTMIVQAISLLDDLDKELNNYIMRCREWYGWH
.::.: .: ....::: :. :. .
XP_006 EIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKR
70 80 90 100 110 120
200 210 220 230 240
pF1KB0 FPELGKIISDNLTYCKCLQKVGDR--KNYASAKLSELLPEEVEAEVKAAAEISMGTEVSE
:::: ... . : : . ....:. : . .:...: . . :...: ..: ..::
XP_006 FPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLSE
130 140 150 160 170 180
250 260 270 280 290 300
pF1KB0 EDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGELVGARLIAHAGSLLNL
:.. . . : ...:.. . ..:::...:: ::::.....: ..:.... ::.: ::
XP_006 EELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTNL
190 200 210 220 230 240
310 320 330 340 350 360
pF1KB0 AKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQTSPKHKGKISRMLAAKTVL
.: : ....:::.. . ...: :. : :::...: . : . : .:..::: .:
XP_006 SKMPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCTL
250 260 270 280 290 300
370 380 390 400 410 420
pF1KB0 AIRYDAFGEDSSSAMGVENRAKLEARL-RTLEDRGIRKISGTGKAL-AKTEKYEHKSEVK
: : :.: :.. . .: : . ..: .. . : ..... : .. .: . :
XP_006 AARVDSFHESTEGKVGYELKDEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYRK
310 320 330 340 350 360
430 440 450 460 470
pF1KB0 TYDPSGDSTLPTCSKKRKIEQVDKEDEITEK---------KAKKAKIK-VKVEEEEEEKV
. : . . ... .. ... :: : :. ..... ..:.: . ..
XP_006 MKERLGLTEIRKQANRMSFGEIE-EDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARI
370 380 390 400 410 420
480 490 500 510 520
pF1KB0 AEEEETSVKKKKK-RGKKKHIKEEPLSEEE-----PCTSTAIASPEKKKKKKKKRENED
.. . ...:.. : :. :... . : . :..:. .::
XP_006 SKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYF
430 440 450 460 470 480
XP_006 SSMAEFLKVKGEKSGLMST
490
>>NP_056444 (OMIM: 600138,606419) U4/U6 small nuclear ri (499 aa)
initn: 405 init1: 327 opt: 430 Z-score: 324.6 bits: 69.6 E(85289): 2.4e-11
Smith-Waterman score: 440; 23.6% identity (61.2% similar) in 381 aa overlap (161-521:92-471)
140 150 160 170 180 190
pF1KB0 EPREMAAMCLGLAHSLSRYRLKFSADKVDTMIVQAISLLDDLDKELNNYIMRCREWYGWH
.::.: .: ....::: :. :. .
NP_056 EIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKR
70 80 90 100 110 120
200 210 220 230 240
pF1KB0 FPELGKIISDNLTYCKCLQKVGDR--KNYASAKLSELLPEEVEAEVKAAAEISMGTEVSE
:::: ... . : : . ....:. : . .:...: . . :...: ..: ..::
NP_056 FPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLSE
130 140 150 160 170 180
250 260 270 280 290 300
pF1KB0 EDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGELVGARLIAHAGSLLNL
:.. . . : ...:.. . ..:::...:: ::::.....: ..:.... ::.: ::
NP_056 EELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTNL
190 200 210 220 230 240
310 320 330 340 350 360
pF1KB0 AKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQTSPKHKGKISRMLAAKTVL
.: : ....:::.. . ...: :. : :::...: . : . : .:..::: .:
NP_056 SKMPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCTL
250 260 270 280 290 300
370 380 390 400 410 420
pF1KB0 AIRYDAFGEDSSSAMGVENRAKLEARL-RTLEDRGIRKISGTGKAL-AKTEKYEHKSEVK
: : :.: :.. . .: : . ..: .. . : ..... : .. .: . :
NP_056 AARVDSFHESTEGKVGYELKDEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYRK
310 320 330 340 350 360
430 440 450 460 470
pF1KB0 TYDPSGDSTLPTCSKKRKIEQVDKEDEITEK---------KAKKAKIK-VKVEEEEEEKV
. : . . ... .. ... :: : :. ..... ..:.: . ..
NP_056 MKERLGLTEIRKQANRMSFGEIE-EDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARI
370 380 390 400 410 420
480 490 500 510 520
pF1KB0 AEEEETSVKKKKK-RGKKKHIKEEPLSEEE-----PCTSTAIASPEKKKKKKKKRENED
.. . ...:.. : :. :... . : . :..:. .::
NP_056 SKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYF
430 440 450 460 470 480
NP_056 SSMAEFLKVKGEKSGLMST
490
529 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 08:04:08 2016 done: Sat Nov 5 08:04:09 2016
Total Scan time: 10.290 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]