Result of FASTA (omim) for
pF1KB0476
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0476, 1019 aa
1>>>pF1KB0476 1019 - 1019 aa - 1019 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0013+/-0.000474; mu= 17.6443+/- 0.030
mean_var=72.6941+/-14.557, 0's: 0 Z-trim(109.1): 41 B-trim: 725 in 1/51
Lambda= 0.150427
statistics sampled from 17227 (17254) to 17227 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.553), E-opt: 0.2 (0.202), width: 16
Scan time: 12.960
The best scores are: opt bits E(85289)
NP_004960 (OMIM: 146680) insulin-degrading enzyme (1019) 6844 1495.6 0
NP_001309722 (OMIM: 146680) insulin-degrading enzy (1019) 6703 1465.0 0
XP_016871677 (OMIM: 146680) PREDICTED: insulin-deg ( 978) 6555 1432.8 0
XP_016871678 (OMIM: 146680) PREDICTED: insulin-deg ( 978) 6555 1432.8 0
NP_001309724 (OMIM: 146680) insulin-degrading enzy ( 978) 6555 1432.8 0
NP_001309725 (OMIM: 146680) insulin-degrading enzy ( 978) 6555 1432.8 0
XP_016871676 (OMIM: 146680) PREDICTED: insulin-deg ( 978) 6555 1432.8 0
XP_016871679 (OMIM: 146680) PREDICTED: insulin-deg ( 978) 6414 1402.2 0
NP_001309723 (OMIM: 146680) insulin-degrading enzy ( 980) 5083 1113.4 0
NP_001159418 (OMIM: 146680) insulin-degrading enzy ( 464) 3097 682.3 1.7e-195
NP_001309726 (OMIM: 146680) insulin-degrading enzy ( 464) 2956 651.7 2.7e-186
NP_001229290 (OMIM: 602651) nardilysin isoform c [ (1087) 1883 418.9 7.3e-116
XP_011539824 (OMIM: 602651) PREDICTED: nardilysin (1109) 1883 418.9 7.5e-116
NP_002516 (OMIM: 602651) nardilysin isoform a [Hom (1219) 1883 418.9 8.1e-116
XP_016856864 (OMIM: 602651) PREDICTED: nardilysin (1019) 1878 417.8 1.5e-115
XP_011539825 (OMIM: 602651) PREDICTED: nardilysin (1019) 1878 417.8 1.5e-115
NP_001095132 (OMIM: 602651) nardilysin isoform b p (1151) 1878 417.9 1.6e-115
XP_005270960 (OMIM: 602651) PREDICTED: nardilysin ( 914) 1772 394.8 1.1e-108
XP_011539827 (OMIM: 602651) PREDICTED: nardilysin ( 914) 1772 394.8 1.1e-108
NP_004270 (OMIM: 603131) mitochondrial-processing ( 489) 170 47.1 0.00029
XP_006716244 (OMIM: 603131) PREDICTED: mitochondri ( 506) 170 47.1 0.0003
XP_005250774 (OMIM: 603131) PREDICTED: mitochondri ( 508) 170 47.1 0.0003
NP_003356 (OMIM: 191328) cytochrome b-c1 complex s ( 480) 153 43.4 0.0037
>>NP_004960 (OMIM: 146680) insulin-degrading enzyme isof (1019 aa)
initn: 6844 init1: 6844 opt: 6844 Z-score: 8020.1 bits: 1495.6 E(85289): 0
Smith-Waterman score: 6844; 100.0% identity (100.0% similar) in 1019 aa overlap (1-1019:1-1019)
10 20 30 40 50 60
pF1KB0 MRYRLAWLLHPALPSTFRSVLGARLPPPERLCGFQKKTYSKMNNPAIKRIGNHITKSPED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MRYRLAWLLHPALPSTFRSVLGARLPPPERLCGFQKKTYSKMNNPAIKRIGNHITKSPED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 KREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 YPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 REVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 REVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 LLKFHSAYYSSNLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LLKFHSAYYSSNLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 LYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 GGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 AFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 VSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 EKEATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EKEATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 KDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 IIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 SRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 QRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 NGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 SAECAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SAECAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLA
910 920 930 940 950 960
970 980 990 1000 1010
pF1KB0 REMDSCPVVGEFPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 REMDSCPVVGEFPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
970 980 990 1000 1010
>>NP_001309722 (OMIM: 146680) insulin-degrading enzyme i (1019 aa)
initn: 6703 init1: 6703 opt: 6703 Z-score: 7854.8 bits: 1465.0 E(85289): 0
Smith-Waterman score: 6703; 97.7% identity (99.3% similar) in 1019 aa overlap (1-1019:1-1019)
10 20 30 40 50 60
pF1KB0 MRYRLAWLLHPALPSTFRSVLGARLPPPERLCGFQKKTYSKMNNPAIKRIGNHITKSPED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRYRLAWLLHPALPSTFRSVLGARLPPPERLCGFQKKTYSKMNNPAIKRIGNHITKSPED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 KREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 YPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 REVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 LLKFHSAYYSSNLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKFHSAYYSSNLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 LYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 GGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 AFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 VSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 EKEATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELL
:::::::::::::::::::::::::::::::::::::::: . :.:::::::.::...::
NP_001 EKEATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSRYIYADPLHCNMTYLFIRLL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 KDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFE
::.:.::.:::.:.:::: . . . .. ::::::::::::::::::::::::::::::::
NP_001 KDDLKEYTYAARLSGLSYGIASGMNAILLSVKGYNDKQPILLKKIIEKMATFEIDEKRFE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 IIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 SRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 QRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 NGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 SAECAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAECAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLA
910 920 930 940 950 960
970 980 990 1000 1010
pF1KB0 REMDSCPVVGEFPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REMDSCPVVGEFPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
970 980 990 1000 1010
>>XP_016871677 (OMIM: 146680) PREDICTED: insulin-degradi (978 aa)
initn: 6555 init1: 6555 opt: 6555 Z-score: 7681.5 bits: 1432.8 E(85289): 0
Smith-Waterman score: 6555; 100.0% identity (100.0% similar) in 978 aa overlap (42-1019:1-978)
20 30 40 50 60 70
pF1KB0 ALPSTFRSVLGARLPPPERLCGFQKKTYSKMNNPAIKRIGNHITKSPEDKREYRGLELAN
::::::::::::::::::::::::::::::
XP_016 MNNPAIKRIGNHITKSPEDKREYRGLELAN
10 20 30
80 90 100 110 120 130
pF1KB0 GIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB0 SEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHE
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB0 KNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSS
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB0 NLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIR
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB0 NLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFM
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB0 FFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPR
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB0 GYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDR
400 410 420 430 440 450
500 510 520 530 540 550
pF1KB0 TEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALI
460 470 480 490 500 510
560 570 580 590 600 610
pF1KB0 KDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAA
520 530 540 550 560 570
620 630 640 650 660 670
pF1KB0 ELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLN
580 590 600 610 620 630
680 690 700 710 720 730
pF1KB0 NFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHG
640 650 660 670 680 690
740 750 760 770 780 790
pF1KB0 NITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGI
700 710 720 730 740 750
800 810 820 830 840 850
pF1KB0 EIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQ
760 770 780 790 800 810
860 870 880 890 900 910
pF1KB0 SEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEI
820 830 840 850 860 870
920 930 940 950 960 970
pF1KB0 ISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVVGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVVGE
880 890 900 910 920 930
980 990 1000 1010
pF1KB0 FPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
940 950 960 970
>>XP_016871678 (OMIM: 146680) PREDICTED: insulin-degradi (978 aa)
initn: 6555 init1: 6555 opt: 6555 Z-score: 7681.5 bits: 1432.8 E(85289): 0
Smith-Waterman score: 6555; 100.0% identity (100.0% similar) in 978 aa overlap (42-1019:1-978)
20 30 40 50 60 70
pF1KB0 ALPSTFRSVLGARLPPPERLCGFQKKTYSKMNNPAIKRIGNHITKSPEDKREYRGLELAN
::::::::::::::::::::::::::::::
XP_016 MNNPAIKRIGNHITKSPEDKREYRGLELAN
10 20 30
80 90 100 110 120 130
pF1KB0 GIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB0 SEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHE
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB0 KNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSS
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB0 NLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIR
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB0 NLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFM
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB0 FFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPR
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB0 GYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDR
400 410 420 430 440 450
500 510 520 530 540 550
pF1KB0 TEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALI
460 470 480 490 500 510
560 570 580 590 600 610
pF1KB0 KDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAA
520 530 540 550 560 570
620 630 640 650 660 670
pF1KB0 ELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLN
580 590 600 610 620 630
680 690 700 710 720 730
pF1KB0 NFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHG
640 650 660 670 680 690
740 750 760 770 780 790
pF1KB0 NITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGI
700 710 720 730 740 750
800 810 820 830 840 850
pF1KB0 EIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQ
760 770 780 790 800 810
860 870 880 890 900 910
pF1KB0 SEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEI
820 830 840 850 860 870
920 930 940 950 960 970
pF1KB0 ISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVVGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVVGE
880 890 900 910 920 930
980 990 1000 1010
pF1KB0 FPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
940 950 960 970
>>NP_001309724 (OMIM: 146680) insulin-degrading enzyme i (978 aa)
initn: 6555 init1: 6555 opt: 6555 Z-score: 7681.5 bits: 1432.8 E(85289): 0
Smith-Waterman score: 6555; 100.0% identity (100.0% similar) in 978 aa overlap (42-1019:1-978)
20 30 40 50 60 70
pF1KB0 ALPSTFRSVLGARLPPPERLCGFQKKTYSKMNNPAIKRIGNHITKSPEDKREYRGLELAN
::::::::::::::::::::::::::::::
NP_001 MNNPAIKRIGNHITKSPEDKREYRGLELAN
10 20 30
80 90 100 110 120 130
pF1KB0 GIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB0 SEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHE
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB0 KNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSS
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB0 NLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIR
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB0 NLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFM
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB0 FFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPR
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB0 GYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDR
400 410 420 430 440 450
500 510 520 530 540 550
pF1KB0 TEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALI
460 470 480 490 500 510
560 570 580 590 600 610
pF1KB0 KDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAA
520 530 540 550 560 570
620 630 640 650 660 670
pF1KB0 ELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLN
580 590 600 610 620 630
680 690 700 710 720 730
pF1KB0 NFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHG
640 650 660 670 680 690
740 750 760 770 780 790
pF1KB0 NITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGI
700 710 720 730 740 750
800 810 820 830 840 850
pF1KB0 EIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQ
760 770 780 790 800 810
860 870 880 890 900 910
pF1KB0 SEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEI
820 830 840 850 860 870
920 930 940 950 960 970
pF1KB0 ISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVVGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVVGE
880 890 900 910 920 930
980 990 1000 1010
pF1KB0 FPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
940 950 960 970
>>NP_001309725 (OMIM: 146680) insulin-degrading enzyme i (978 aa)
initn: 6555 init1: 6555 opt: 6555 Z-score: 7681.5 bits: 1432.8 E(85289): 0
Smith-Waterman score: 6555; 100.0% identity (100.0% similar) in 978 aa overlap (42-1019:1-978)
20 30 40 50 60 70
pF1KB0 ALPSTFRSVLGARLPPPERLCGFQKKTYSKMNNPAIKRIGNHITKSPEDKREYRGLELAN
::::::::::::::::::::::::::::::
NP_001 MNNPAIKRIGNHITKSPEDKREYRGLELAN
10 20 30
80 90 100 110 120 130
pF1KB0 GIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB0 SEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHE
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB0 KNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSS
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB0 NLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIR
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB0 NLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFM
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB0 FFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPR
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB0 GYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDR
400 410 420 430 440 450
500 510 520 530 540 550
pF1KB0 TEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALI
460 470 480 490 500 510
560 570 580 590 600 610
pF1KB0 KDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAA
520 530 540 550 560 570
620 630 640 650 660 670
pF1KB0 ELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLN
580 590 600 610 620 630
680 690 700 710 720 730
pF1KB0 NFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHG
640 650 660 670 680 690
740 750 760 770 780 790
pF1KB0 NITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGI
700 710 720 730 740 750
800 810 820 830 840 850
pF1KB0 EIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQ
760 770 780 790 800 810
860 870 880 890 900 910
pF1KB0 SEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEI
820 830 840 850 860 870
920 930 940 950 960 970
pF1KB0 ISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVVGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVVGE
880 890 900 910 920 930
980 990 1000 1010
pF1KB0 FPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
940 950 960 970
>>XP_016871676 (OMIM: 146680) PREDICTED: insulin-degradi (978 aa)
initn: 6555 init1: 6555 opt: 6555 Z-score: 7681.5 bits: 1432.8 E(85289): 0
Smith-Waterman score: 6555; 100.0% identity (100.0% similar) in 978 aa overlap (42-1019:1-978)
20 30 40 50 60 70
pF1KB0 ALPSTFRSVLGARLPPPERLCGFQKKTYSKMNNPAIKRIGNHITKSPEDKREYRGLELAN
::::::::::::::::::::::::::::::
XP_016 MNNPAIKRIGNHITKSPEDKREYRGLELAN
10 20 30
80 90 100 110 120 130
pF1KB0 GIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB0 SEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHE
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB0 KNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSS
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB0 NLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIR
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB0 NLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFM
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB0 FFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPR
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB0 GYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDR
400 410 420 430 440 450
500 510 520 530 540 550
pF1KB0 TEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALI
460 470 480 490 500 510
560 570 580 590 600 610
pF1KB0 KDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAA
520 530 540 550 560 570
620 630 640 650 660 670
pF1KB0 ELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLN
580 590 600 610 620 630
680 690 700 710 720 730
pF1KB0 NFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHG
640 650 660 670 680 690
740 750 760 770 780 790
pF1KB0 NITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGI
700 710 720 730 740 750
800 810 820 830 840 850
pF1KB0 EIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQ
760 770 780 790 800 810
860 870 880 890 900 910
pF1KB0 SEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEI
820 830 840 850 860 870
920 930 940 950 960 970
pF1KB0 ISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVVGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVVGE
880 890 900 910 920 930
980 990 1000 1010
pF1KB0 FPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
940 950 960 970
>>XP_016871679 (OMIM: 146680) PREDICTED: insulin-degradi (978 aa)
initn: 6414 init1: 6414 opt: 6414 Z-score: 7516.1 bits: 1402.2 E(85289): 0
Smith-Waterman score: 6414; 97.6% identity (99.3% similar) in 978 aa overlap (42-1019:1-978)
20 30 40 50 60 70
pF1KB0 ALPSTFRSVLGARLPPPERLCGFQKKTYSKMNNPAIKRIGNHITKSPEDKREYRGLELAN
::::::::::::::::::::::::::::::
XP_016 MNNPAIKRIGNHITKSPEDKREYRGLELAN
10 20 30
80 90 100 110 120 130
pF1KB0 GIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB0 SEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHE
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB0 KNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSS
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB0 NLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIR
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB0 NLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFM
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB0 FFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPR
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB0 GYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDR
400 410 420 430 440 450
500 510 520 530 540 550
pF1KB0 TEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALI
460 470 480 490 500 510
560 570 580 590 600 610
pF1KB0 KDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAA
::::::::::::::::::::::::::::: . :.:::::::.::...::::.:.::.:::
XP_016 KDTAMSKLWFKQDDKFFLPKACLNFEFFSRYIYADPLHCNMTYLFIRLLKDDLKEYTYAA
520 530 540 550 560 570
620 630 640 650 660 670
pF1KB0 ELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLN
.:.:::: . . . .. :::::::::::::::::::::::::::::::::::::::::::
XP_016 RLSGLSYGIASGMNAILLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLN
580 590 600 610 620 630
680 690 700 710 720 730
pF1KB0 NFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHG
640 650 660 670 680 690
740 750 760 770 780 790
pF1KB0 NITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGI
700 710 720 730 740 750
800 810 820 830 840 850
pF1KB0 EIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQ
760 770 780 790 800 810
860 870 880 890 900 910
pF1KB0 SEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEI
820 830 840 850 860 870
920 930 940 950 960 970
pF1KB0 ISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVVGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVVGE
880 890 900 910 920 930
980 990 1000 1010
pF1KB0 FPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
940 950 960 970
>>NP_001309723 (OMIM: 146680) insulin-degrading enzyme i (980 aa)
initn: 5083 init1: 5083 opt: 5083 Z-score: 5955.0 bits: 1113.4 E(85289): 0
Smith-Waterman score: 6501; 96.2% identity (96.2% similar) in 1019 aa overlap (1-1019:1-980)
10 20 30 40 50 60
pF1KB0 MRYRLAWLLHPALPSTFRSVLGARLPPPERLCGFQKKTYSKMNNPAIKRIGNHITKSPED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRYRLAWLLHPALPSTFRSVLGARLPPPERLCGFQKKTYSKMNNPAIKRIGNHITKSPED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 KREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 YPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 REVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQE
:::::::::::::::::::::::::::::::::::::::::
NP_001 REVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTG-------------------
190 200 210 220
250 260 270 280 290 300
pF1KB0 LLKFHSAYYSSNLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQ
::::::::::::::::::::::::::::::::::::::::
NP_001 --------------------RESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQ
230 240 250 260
310 320 330 340 350 360
pF1KB0 LYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLV
270 280 290 300 310 320
370 380 390 400 410 420
pF1KB0 GGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAV
330 340 350 360 370 380
430 440 450 460 470 480
pF1KB0 AFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAI
390 400 410 420 430 440
490 500 510 520 530 540
pF1KB0 VSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPL
450 460 470 480 490 500
550 560 570 580 590 600
pF1KB0 EKEATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKEATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELL
510 520 530 540 550 560
610 620 630 640 650 660
pF1KB0 KDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFE
570 580 590 600 610 620
670 680 690 700 710 720
pF1KB0 IIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLL
630 640 650 660 670 680
730 740 750 760 770 780
pF1KB0 SRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQ
690 700 710 720 730 740
790 800 810 820 830 840
pF1KB0 QRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRA
750 760 770 780 790 800
850 860 870 880 890 900
pF1KB0 NGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKL
810 820 830 840 850 860
910 920 930 940 950 960
pF1KB0 SAECAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAECAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLA
870 880 890 900 910 920
970 980 990 1000 1010
pF1KB0 REMDSCPVVGEFPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REMDSCPVVGEFPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
930 940 950 960 970 980
>>NP_001159418 (OMIM: 146680) insulin-degrading enzyme i (464 aa)
initn: 3097 init1: 3097 opt: 3097 Z-score: 3630.9 bits: 682.3 E(85289): 1.7e-195
Smith-Waterman score: 3097; 100.0% identity (100.0% similar) in 464 aa overlap (556-1019:1-464)
530 540 550 560 570 580
pF1KB0 TKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYV
::::::::::::::::::::::::::::::
NP_001 MSKLWFKQDDKFFLPKACLNFEFFSPFAYV
10 20 30
590 600 610 620 630 640
pF1KB0 DPLHCNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPLHCNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKI
40 50 60 70 80 90
650 660 670 680 690 700
pF1KB0 IEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALD
100 110 120 130 140 150
710 720 730 740 750 760
pF1KB0 DVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVR
160 170 180 190 200 210
770 780 790 800 810 820
pF1KB0 YREVQLPDRGWFVYQQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YREVQLPDRGWFVYQQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRT
220 230 240 250 260 270
830 840 850 860 870 880
pF1KB0 KEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKH
280 290 300 310 320 330
890 900 910 920 930 940
pF1KB0 IQALAIRRLDKPKKLSAECAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQALAIRRLDKPKKLSAECAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLA
340 350 360 370 380 390
950 960 970 980 990 1000
pF1KB0 VDAPRRHKVSVHVLAREMDSCPVVGEFPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDAPRRHKVSVHVLAREMDSCPVVGEFPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLF
400 410 420 430 440 450
1010
pF1KB0 PLVKPHINFMAAKL
::::::::::::::
NP_001 PLVKPHINFMAAKL
460
1019 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:04:17 2016 done: Sat Nov 5 17:04:19 2016
Total Scan time: 12.960 Total Display time: 0.420
Function used was FASTA [36.3.4 Apr, 2011]