FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB0417, 471 aa
  1>>>pF1KB0417 471 - 471 aa - 471 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.8401+/-0.00131; mu= 6.1989+/- 0.076
 mean_var=212.9339+/-47.332, 0's: 0 Z-trim(106.4): 314  B-trim: 327 in 1/50
 Lambda= 0.087893
 statistics sampled from 8602 (8972) to 8602 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.636), E-opt: 0.2 (0.276), width:  16
 Scan time:  3.140

The best scores are:                                      opt bits E(32554)
CCDS32487.1 MLKL gene_id:197259|Hs108|chr16        ( 471) 3083 404.5 1.3e-112
CCDS45528.1 MLKL gene_id:197259|Hs108|chr16        ( 263) 1187 163.8   2e-40


>>CCDS32487.1 MLKL gene_id:197259|Hs108|chr16             (471 aa)
 initn: 3083 init1: 3083 opt: 3083  Z-score: 2135.5  bits: 404.5 E(32554): 1.3e-112
Smith-Waterman score: 3083; 100.0% identity (100.0% similar) in 471 aa overlap (1-471:1-471)

               10        20        30        40        50        60
pF1KB0 MENLKHIITLGQVIHKRCEEMKYCKKQCRRLGHRVLGLIKPLEMLQDQGKRSVPSEKLTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 MENLKHIITLGQVIHKRCEEMKYCKKQCRRLGHRVLGLIKPLEMLQDQGKRSVPSEKLTT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 AMNRFKAALEEANGEIEKFSNRSNICRFLTASQDKILFKDVNRKLSDVWKELSLLLQVEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 AMNRFKAALEEANGEIEKFSNRSNICRFLTASQDKILFKDVNRKLSDVWKELSLLLQVEQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 RMPVSPISQGASWAQEDQQDADEDRRAFQMLRRDNEKIEASLRRLEINMKEIKETLRQYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 RMPVSPISQGASWAQEDQQDADEDRRAFQMLRRDNEKIEASLRRLEINMKEIKETLRQYL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 PPKCMQEIPQEQIKEIKKEQLSGSPWILLRENEVSTLYKGEYHRAPVAIKVFKKLQAGSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 PPKCMQEIPQEQIKEIKKEQLSGSPWILLRENEVSTLYKGEYHRAPVAIKVFKKLQAGSI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 AIVRQTFNKEIKTMKKFESPNILRIFGICIDETVTPPQFSIVMEYCELGTLRELLDREKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 AIVRQTFNKEIKTMKKFESPNILRIFGICIDETVTPPQFSIVMEYCELGTLRELLDREKD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 LTLGKRMVLVLGAARGLYRLHHSEAPELHGKIRSSNFLVTQGYQVKLAGFELRKTQTSMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 LTLGKRMVLVLGAARGLYRLHHSEAPELHGKIRSSNFLVTQGYQVKLAGFELRKTQTSMS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 LGTTREKTDRVKSTAYLSPQELEDVFYQYDVKSEIYSFGIVLWEIATGDIPFQGCNSEKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 LGTTREKTDRVKSTAYLSPQELEDVFYQYDVKSEIYSFGIVLWEIATGDIPFQGCNSEKI
              370       380       390       400       410       420

              430       440       450       460       470 
pF1KB0 RKLVAVKRQQEPLGEDCPSELREIIDECRAHDPSVRPSVDEILKKLSTFSK
       :::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 RKLVAVKRQQEPLGEDCPSELREIIDECRAHDPSVRPSVDEILKKLSTFSK
              430       440       450       460       470 

>>CCDS45528.1 MLKL gene_id:197259|Hs108|chr16             (263 aa)
 initn: 1568 init1: 1168 opt: 1187  Z-score: 839.3  bits: 163.8 E(32554): 2e-40
Smith-Waterman score: 1187; 90.3% identity (93.2% similar) in 206 aa overlap (1-203:1-206)

               10        20        30        40        50        60
pF1KB0 MENLKHIITLGQVIHKRCEEMKYCKKQCRRLGHRVLGLIKPLEMLQDQGKRSVPSEKLTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MENLKHIITLGQVIHKRCEEMKYCKKQCRRLGHRVLGLIKPLEMLQDQGKRSVPSEKLTT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 AMNRFKAALEEANGEIEKFSNRSNICRFLTASQDKILFKDVNRKLSDVWKELSLLLQVEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 AMNRFKAALEEANGEIEKFSNRSNICRFLTASQDKILFKDVNRKLSDVWKELSLLLQVEQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 RMPVSPISQGASWAQEDQQDADEDRRAFQMLRRDNEKIEASLRRLEINMKEIKETLRQYL
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
CCDS45 RMPVSPISQGASWAQEDQQDADEDRRAFQMLRRDNEKIEASLRRLEINMKEIKETLRQSL
              130       140       150       160       170       180

                 190       200       210       220       230       
pF1KB0 PP---KCMQEIPQEQIKEIKKEQLSGSPWILLRENEVSTLYKGEYHRAPVAIKVFKKLQA
            :   :: . ..:..:  . ::                                  
CCDS45 ESSSGKSPLEISRFKVKNVKTGSASGCNSEKIRKLVAVKRQQEPLGEDCPSELREIIDEC
              190       200       210       220       230       240




471 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 18:45:36 2016 done: Sat Nov  5 18:45:36 2016
 Total Scan time:  3.140 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]