Result of FASTA (omim) for
pF1KA1745
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1745, 837 aa
1>>>pF1KA1745 837 - 837 aa - 837 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9213+/-0.000311; mu= 18.4859+/- 0.020
mean_var=94.0682+/-19.304, 0's: 0 Z-trim(118.3): 201 B-trim: 0 in 0/52
Lambda= 0.132237
statistics sampled from 30834 (31039) to 30834 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.364), width: 16
Scan time: 10.430
The best scores are: opt bits E(85289)
NP_064595 (OMIM: 617029) semaphorin-4B isoform 1 p ( 837) 5737 1105.1 0
NP_945119 (OMIM: 617029) semaphorin-4B isoform 1 p ( 837) 5737 1105.1 0
NP_001310960 (OMIM: 617029) semaphorin-4B isoform ( 890) 5737 1105.1 0
NP_001310959 (OMIM: 617029) semaphorin-4B isoform ( 681) 4670 901.4 0
NP_001310962 (OMIM: 617029) semaphorin-4B isoform ( 681) 4670 901.4 0
NP_001310961 (OMIM: 617029) semaphorin-4B isoform ( 602) 3859 746.7 7.2e-215
NP_001310963 (OMIM: 617029) semaphorin-4B isoform ( 847) 3457 670.1 1.2e-191
NP_001310958 (OMIM: 617029) semaphorin-4B isoform ( 699) 3362 651.9 2.8e-186
XP_011509685 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 1624 320.4 2.1e-86
XP_011509680 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 1624 320.4 2.1e-86
XP_011509684 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 1624 320.4 2.1e-86
XP_011509681 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 1624 320.4 2.1e-86
XP_011509683 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 1624 320.4 2.1e-86
XP_011509682 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 1624 320.4 2.1e-86
NP_060259 (OMIM: 604462) semaphorin-4C precursor [ ( 833) 1624 320.4 2.1e-86
XP_016859882 (OMIM: 604462) PREDICTED: semaphorin- ( 875) 1624 320.4 2.2e-86
XP_016869682 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1491 295.0 9.4e-79
XP_011516435 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1491 295.0 9.4e-79
XP_016869684 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1491 295.0 9.4e-79
XP_011516427 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1491 295.0 9.4e-79
XP_011516432 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1491 295.0 9.4e-79
XP_016869687 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1491 295.0 9.4e-79
XP_005251711 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1491 295.0 9.4e-79
XP_011516431 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1491 295.0 9.4e-79
XP_011516430 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1491 295.0 9.4e-79
XP_011516429 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1491 295.0 9.4e-79
XP_011516436 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1491 295.0 9.4e-79
XP_011516433 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1491 295.0 9.4e-79
XP_011516426 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1491 295.0 9.4e-79
NP_006369 (OMIM: 601866) semaphorin-4D isoform 1 p ( 862) 1491 295.0 9.4e-79
XP_016869685 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1491 295.0 9.4e-79
XP_011516425 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1491 295.0 9.4e-79
XP_016869686 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1491 295.0 9.4e-79
XP_016869683 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1491 295.0 9.4e-79
NP_001135759 (OMIM: 601866) semaphorin-4D isoform ( 738) 1461 289.3 4.4e-77
XP_006712669 (OMIM: 604462) PREDICTED: semaphorin- ( 495) 1413 280.0 1.8e-74
XP_011530779 (OMIM: 603706) PREDICTED: semaphorin- ( 597) 1373 272.4 4.2e-72
XP_011530778 (OMIM: 603706) PREDICTED: semaphorin- ( 600) 1373 272.4 4.2e-72
XP_011530777 (OMIM: 603706) PREDICTED: semaphorin- ( 624) 1373 272.4 4.4e-72
NP_004254 (OMIM: 603706) semaphorin-4F isoform 1 p ( 770) 1373 272.5 5.2e-72
XP_016859883 (OMIM: 604462) PREDICTED: semaphorin- ( 692) 1303 259.1 5e-68
XP_016869688 (OMIM: 601866) PREDICTED: semaphorin- ( 534) 1227 244.5 9.4e-64
XP_016858661 (OMIM: 603706) PREDICTED: semaphorin- ( 668) 1218 242.9 3.7e-63
NP_001276989 (OMIM: 601281) semaphorin-3B isoform ( 749) 1159 231.7 9.8e-60
NP_004627 (OMIM: 601281) semaphorin-3B isoform 1 p ( 749) 1159 231.7 9.8e-60
NP_001005914 (OMIM: 601281) semaphorin-3B isoform ( 748) 1158 231.5 1.1e-59
NP_006370 (OMIM: 602645) semaphorin-3C precursor [ ( 751) 1152 230.3 2.5e-59
NP_001305729 (OMIM: 601124) semaphorin-3F isoform ( 754) 1132 226.5 3.5e-58
XP_005265439 (OMIM: 601124) PREDICTED: semaphorin- ( 754) 1132 226.5 3.5e-58
XP_005250170 (OMIM: 602645) PREDICTED: semaphorin- ( 693) 1129 225.9 4.9e-58
>>NP_064595 (OMIM: 617029) semaphorin-4B isoform 1 precu (837 aa)
initn: 5737 init1: 5737 opt: 5737 Z-score: 5912.9 bits: 1105.1 E(85289): 0
Smith-Waterman score: 5737; 100.0% identity (100.0% similar) in 837 aa overlap (1-837:1-837)
10 20 30 40 50 60
pF1KA1 MLRTAMGLRSWLAAPWGALPPRPPLLLLLLLLLLLQPPPPTWALSPRISLPLGSEERPFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MLRTAMGLRSWLAAPWGALPPRPPLLLLLLLLLLLQPPPPTWALSPRISLPLGSEERPFL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 RFEAEHISNYTALLLSRDGRTLYVGAREALFALSSNLSFLPGGEYQELLWGADAEKKQQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 RFEAEHISNYTALLLSRDGRTLYVGAREALFALSSNLSFLPGGEYQELLWGADAEKKQQC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 SFKGKDPQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 SFKGKDPQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 GKGRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 GKGRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 VASAYIPESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQQRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 VASAYIPESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQQRW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 TSFLKAQLLCSRPDDGFPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 TSFLKAQLLCSRPDDGFPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 FTMKDVQRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 FTMKDVQRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 NFLKDHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLHHTYDVLFLGTGDGRLHKAVSVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 NFLKDHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLHHTYDVLFLGTGDGRLHKAVSVG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 PRVHIIEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 PRVHIIEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 PYCAWSGSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSASSVVSPSFVPTGEKPCEQVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 PYCAWSGSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSASSVVSPSFVPTGEKPCEQVQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 FQPNTVNTLACPLLSNLATRLWLRNGAPVNASASCHVLPTGDLLLVGTQQLGEFQCWSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 FQPNTVNTLACPLLSNLATRLWLRNGAPVNASASCHVLPTGDLLLVGTQQLGEFQCWSLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 EGFQQLVASYCPEVVEDGVADQTDEGGSVPVIISTSRVSAPAGGKASWGADRSYWKEFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 EGFQQLVASYCPEVVEDGVADQTDEGGSVPVIISTSRVSAPAGGKASWGADRSYWKEFLV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 MCTLFVLAVLLPVLFLLYRHRNSMKVFLKQGECASVHPKTCPVVLPPETRPLNGLGPPST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MCTLFVLAVLLPVLFLLYRHRNSMKVFLKQGECASVHPKTCPVVLPPETRPLNGLGPPST
730 740 750 760 770 780
790 800 810 820 830
pF1KA1 PLDHRGYQSLSDSPPGSRVFTESEKRPLSIQDSFVEVSPVCPRPRVRLGSEIRDSVV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 PLDHRGYQSLSDSPPGSRVFTESEKRPLSIQDSFVEVSPVCPRPRVRLGSEIRDSVV
790 800 810 820 830
>>NP_945119 (OMIM: 617029) semaphorin-4B isoform 1 precu (837 aa)
initn: 5737 init1: 5737 opt: 5737 Z-score: 5912.9 bits: 1105.1 E(85289): 0
Smith-Waterman score: 5737; 100.0% identity (100.0% similar) in 837 aa overlap (1-837:1-837)
10 20 30 40 50 60
pF1KA1 MLRTAMGLRSWLAAPWGALPPRPPLLLLLLLLLLLQPPPPTWALSPRISLPLGSEERPFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 MLRTAMGLRSWLAAPWGALPPRPPLLLLLLLLLLLQPPPPTWALSPRISLPLGSEERPFL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 RFEAEHISNYTALLLSRDGRTLYVGAREALFALSSNLSFLPGGEYQELLWGADAEKKQQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 RFEAEHISNYTALLLSRDGRTLYVGAREALFALSSNLSFLPGGEYQELLWGADAEKKQQC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 SFKGKDPQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 SFKGKDPQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 GKGRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 GKGRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 VASAYIPESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQQRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 VASAYIPESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQQRW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 TSFLKAQLLCSRPDDGFPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 TSFLKAQLLCSRPDDGFPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 FTMKDVQRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 FTMKDVQRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 NFLKDHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLHHTYDVLFLGTGDGRLHKAVSVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 NFLKDHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLHHTYDVLFLGTGDGRLHKAVSVG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 PRVHIIEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 PRVHIIEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 PYCAWSGSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSASSVVSPSFVPTGEKPCEQVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 PYCAWSGSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSASSVVSPSFVPTGEKPCEQVQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 FQPNTVNTLACPLLSNLATRLWLRNGAPVNASASCHVLPTGDLLLVGTQQLGEFQCWSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 FQPNTVNTLACPLLSNLATRLWLRNGAPVNASASCHVLPTGDLLLVGTQQLGEFQCWSLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 EGFQQLVASYCPEVVEDGVADQTDEGGSVPVIISTSRVSAPAGGKASWGADRSYWKEFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 EGFQQLVASYCPEVVEDGVADQTDEGGSVPVIISTSRVSAPAGGKASWGADRSYWKEFLV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 MCTLFVLAVLLPVLFLLYRHRNSMKVFLKQGECASVHPKTCPVVLPPETRPLNGLGPPST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 MCTLFVLAVLLPVLFLLYRHRNSMKVFLKQGECASVHPKTCPVVLPPETRPLNGLGPPST
730 740 750 760 770 780
790 800 810 820 830
pF1KA1 PLDHRGYQSLSDSPPGSRVFTESEKRPLSIQDSFVEVSPVCPRPRVRLGSEIRDSVV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 PLDHRGYQSLSDSPPGSRVFTESEKRPLSIQDSFVEVSPVCPRPRVRLGSEIRDSVV
790 800 810 820 830
>>NP_001310960 (OMIM: 617029) semaphorin-4B isoform 4 [H (890 aa)
initn: 5737 init1: 5737 opt: 5737 Z-score: 5912.5 bits: 1105.1 E(85289): 0
Smith-Waterman score: 5737; 100.0% identity (100.0% similar) in 837 aa overlap (1-837:54-890)
10 20 30
pF1KA1 MLRTAMGLRSWLAAPWGALPPRPPLLLLLL
::::::::::::::::::::::::::::::
NP_001 GADRGAELPPVSPAEPPEPEPRDTVAPALRMLRTAMGLRSWLAAPWGALPPRPPLLLLLL
30 40 50 60 70 80
40 50 60 70 80 90
pF1KA1 LLLLLQPPPPTWALSPRISLPLGSEERPFLRFEAEHISNYTALLLSRDGRTLYVGAREAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLLLLQPPPPTWALSPRISLPLGSEERPFLRFEAEHISNYTALLLSRDGRTLYVGAREAL
90 100 110 120 130 140
100 110 120 130 140 150
pF1KA1 FALSSNLSFLPGGEYQELLWGADAEKKQQCSFKGKDPQRDCQNYIKILLPLSGSHLFTCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FALSSNLSFLPGGEYQELLWGADAEKKQQCSFKGKDPQRDCQNYIKILLPLSGSHLFTCG
150 160 170 180 190 200
160 170 180 190 200 210
pF1KA1 TAAFSPMCTYINMENFTLARDEKGNVLLEDGKGRCPFDPNFKSTALVVDGELYTGTVSSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAAFSPMCTYINMENFTLARDEKGNVLLEDGKGRCPFDPNFKSTALVVDGELYTGTVSSF
210 220 230 240 250 260
220 230 240 250 260 270
pF1KA1 QGNDPAISRSQSLRPTKTESSLNWLQDPAFVASAYIPESLGSLQGDDDKIYFFFSETGQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGNDPAISRSQSLRPTKTESSLNWLQDPAFVASAYIPESLGSLQGDDDKIYFFFSETGQE
270 280 290 300 310 320
280 290 300 310 320 330
pF1KA1 FEFFENTIVSRIARICKGDEGGERVLQQRWTSFLKAQLLCSRPDDGFPFNVLQDVFTLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEFFENTIVSRIARICKGDEGGERVLQQRWTSFLKAQLLCSRPDDGFPFNVLQDVFTLSP
330 340 350 360 370 380
340 350 360 370 380 390
pF1KA1 SPQDWRDTLFYGVFTSQWHRGTTEGSAVCVFTMKDVQRVFSGLYKEVNRETQQWYTVTHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPQDWRDTLFYGVFTSQWHRGTTEGSAVCVFTMKDVQRVFSGLYKEVNRETQQWYTVTHP
390 400 410 420 430 440
400 410 420 430 440 450
pF1KA1 VPTPRPGACITNSARERKINSSLQLPDRVLNFLKDHFLMDGQVRSRMLLLQPQARYQRVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPTPRPGACITNSARERKINSSLQLPDRVLNFLKDHFLMDGQVRSRMLLLQPQARYQRVA
450 460 470 480 490 500
460 470 480 490 500 510
pF1KA1 VHRVPGLHHTYDVLFLGTGDGRLHKAVSVGPRVHIIEELQIFSSGQPVQNLLLDTHRGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHRVPGLHHTYDVLFLGTGDGRLHKAVSVGPRVHIIEELQIFSSGQPVQNLLLDTHRGLL
510 520 530 540 550 560
520 530 540 550 560 570
pF1KA1 YAASHSGVVQVPMANCSLYRSCGDCLLARDPYCAWSGSSCKHVSLYQPQLATRPWIQDIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YAASHSGVVQVPMANCSLYRSCGDCLLARDPYCAWSGSSCKHVSLYQPQLATRPWIQDIE
570 580 590 600 610 620
580 590 600 610 620 630
pF1KA1 GASAKDLCSASSVVSPSFVPTGEKPCEQVQFQPNTVNTLACPLLSNLATRLWLRNGAPVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GASAKDLCSASSVVSPSFVPTGEKPCEQVQFQPNTVNTLACPLLSNLATRLWLRNGAPVN
630 640 650 660 670 680
640 650 660 670 680 690
pF1KA1 ASASCHVLPTGDLLLVGTQQLGEFQCWSLEEGFQQLVASYCPEVVEDGVADQTDEGGSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASASCHVLPTGDLLLVGTQQLGEFQCWSLEEGFQQLVASYCPEVVEDGVADQTDEGGSVP
690 700 710 720 730 740
700 710 720 730 740 750
pF1KA1 VIISTSRVSAPAGGKASWGADRSYWKEFLVMCTLFVLAVLLPVLFLLYRHRNSMKVFLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIISTSRVSAPAGGKASWGADRSYWKEFLVMCTLFVLAVLLPVLFLLYRHRNSMKVFLKQ
750 760 770 780 790 800
760 770 780 790 800 810
pF1KA1 GECASVHPKTCPVVLPPETRPLNGLGPPSTPLDHRGYQSLSDSPPGSRVFTESEKRPLSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GECASVHPKTCPVVLPPETRPLNGLGPPSTPLDHRGYQSLSDSPPGSRVFTESEKRPLSI
810 820 830 840 850 860
820 830
pF1KA1 QDSFVEVSPVCPRPRVRLGSEIRDSVV
:::::::::::::::::::::::::::
NP_001 QDSFVEVSPVCPRPRVRLGSEIRDSVV
870 880 890
>>NP_001310959 (OMIM: 617029) semaphorin-4B isoform 3 [H (681 aa)
initn: 4670 init1: 4670 opt: 4670 Z-score: 4814.0 bits: 901.4 E(85289): 0
Smith-Waterman score: 4670; 100.0% identity (100.0% similar) in 681 aa overlap (157-837:1-681)
130 140 150 160 170 180
pF1KA1 PQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLEDGKGRCP
::::::::::::::::::::::::::::::
NP_001 MCTYINMENFTLARDEKGNVLLEDGKGRCP
10 20 30
190 200 210 220 230 240
pF1KA1 FDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAFVASAYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAFVASAYI
40 50 60 70 80 90
250 260 270 280 290 300
pF1KA1 PESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQQRWTSFLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQQRWTSFLKA
100 110 120 130 140 150
310 320 330 340 350 360
pF1KA1 QLLCSRPDDGFPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCVFTMKDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLLCSRPDDGFPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCVFTMKDV
160 170 180 190 200 210
370 380 390 400 410 420
pF1KA1 QRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVLNFLKDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVLNFLKDH
220 230 240 250 260 270
430 440 450 460 470 480
pF1KA1 FLMDGQVRSRMLLLQPQARYQRVAVHRVPGLHHTYDVLFLGTGDGRLHKAVSVGPRVHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLMDGQVRSRMLLLQPQARYQRVAVHRVPGLHHTYDVLFLGTGDGRLHKAVSVGPRVHII
280 290 300 310 320 330
490 500 510 520 530 540
pF1KA1 EELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARDPYCAWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARDPYCAWS
340 350 360 370 380 390
550 560 570 580 590 600
pF1KA1 GSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSASSVVSPSFVPTGEKPCEQVQFQPNTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSASSVVSPSFVPTGEKPCEQVQFQPNTV
400 410 420 430 440 450
610 620 630 640 650 660
pF1KA1 NTLACPLLSNLATRLWLRNGAPVNASASCHVLPTGDLLLVGTQQLGEFQCWSLEEGFQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTLACPLLSNLATRLWLRNGAPVNASASCHVLPTGDLLLVGTQQLGEFQCWSLEEGFQQL
460 470 480 490 500 510
670 680 690 700 710 720
pF1KA1 VASYCPEVVEDGVADQTDEGGSVPVIISTSRVSAPAGGKASWGADRSYWKEFLVMCTLFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VASYCPEVVEDGVADQTDEGGSVPVIISTSRVSAPAGGKASWGADRSYWKEFLVMCTLFV
520 530 540 550 560 570
730 740 750 760 770 780
pF1KA1 LAVLLPVLFLLYRHRNSMKVFLKQGECASVHPKTCPVVLPPETRPLNGLGPPSTPLDHRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAVLLPVLFLLYRHRNSMKVFLKQGECASVHPKTCPVVLPPETRPLNGLGPPSTPLDHRG
580 590 600 610 620 630
790 800 810 820 830
pF1KA1 YQSLSDSPPGSRVFTESEKRPLSIQDSFVEVSPVCPRPRVRLGSEIRDSVV
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YQSLSDSPPGSRVFTESEKRPLSIQDSFVEVSPVCPRPRVRLGSEIRDSVV
640 650 660 670 680
>>NP_001310962 (OMIM: 617029) semaphorin-4B isoform 3 [H (681 aa)
initn: 4670 init1: 4670 opt: 4670 Z-score: 4814.0 bits: 901.4 E(85289): 0
Smith-Waterman score: 4670; 100.0% identity (100.0% similar) in 681 aa overlap (157-837:1-681)
130 140 150 160 170 180
pF1KA1 PQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLEDGKGRCP
::::::::::::::::::::::::::::::
NP_001 MCTYINMENFTLARDEKGNVLLEDGKGRCP
10 20 30
190 200 210 220 230 240
pF1KA1 FDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAFVASAYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAFVASAYI
40 50 60 70 80 90
250 260 270 280 290 300
pF1KA1 PESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQQRWTSFLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQQRWTSFLKA
100 110 120 130 140 150
310 320 330 340 350 360
pF1KA1 QLLCSRPDDGFPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCVFTMKDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLLCSRPDDGFPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCVFTMKDV
160 170 180 190 200 210
370 380 390 400 410 420
pF1KA1 QRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVLNFLKDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVLNFLKDH
220 230 240 250 260 270
430 440 450 460 470 480
pF1KA1 FLMDGQVRSRMLLLQPQARYQRVAVHRVPGLHHTYDVLFLGTGDGRLHKAVSVGPRVHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLMDGQVRSRMLLLQPQARYQRVAVHRVPGLHHTYDVLFLGTGDGRLHKAVSVGPRVHII
280 290 300 310 320 330
490 500 510 520 530 540
pF1KA1 EELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARDPYCAWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARDPYCAWS
340 350 360 370 380 390
550 560 570 580 590 600
pF1KA1 GSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSASSVVSPSFVPTGEKPCEQVQFQPNTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSASSVVSPSFVPTGEKPCEQVQFQPNTV
400 410 420 430 440 450
610 620 630 640 650 660
pF1KA1 NTLACPLLSNLATRLWLRNGAPVNASASCHVLPTGDLLLVGTQQLGEFQCWSLEEGFQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTLACPLLSNLATRLWLRNGAPVNASASCHVLPTGDLLLVGTQQLGEFQCWSLEEGFQQL
460 470 480 490 500 510
670 680 690 700 710 720
pF1KA1 VASYCPEVVEDGVADQTDEGGSVPVIISTSRVSAPAGGKASWGADRSYWKEFLVMCTLFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VASYCPEVVEDGVADQTDEGGSVPVIISTSRVSAPAGGKASWGADRSYWKEFLVMCTLFV
520 530 540 550 560 570
730 740 750 760 770 780
pF1KA1 LAVLLPVLFLLYRHRNSMKVFLKQGECASVHPKTCPVVLPPETRPLNGLGPPSTPLDHRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAVLLPVLFLLYRHRNSMKVFLKQGECASVHPKTCPVVLPPETRPLNGLGPPSTPLDHRG
580 590 600 610 620 630
790 800 810 820 830
pF1KA1 YQSLSDSPPGSRVFTESEKRPLSIQDSFVEVSPVCPRPRVRLGSEIRDSVV
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YQSLSDSPPGSRVFTESEKRPLSIQDSFVEVSPVCPRPRVRLGSEIRDSVV
640 650 660 670 680
>>NP_001310961 (OMIM: 617029) semaphorin-4B isoform 5 pr (602 aa)
initn: 3887 init1: 3859 opt: 3859 Z-score: 3978.6 bits: 746.7 E(85289): 7.2e-215
Smith-Waterman score: 3859; 100.0% identity (100.0% similar) in 563 aa overlap (1-563:1-563)
10 20 30 40 50 60
pF1KA1 MLRTAMGLRSWLAAPWGALPPRPPLLLLLLLLLLLQPPPPTWALSPRISLPLGSEERPFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLRTAMGLRSWLAAPWGALPPRPPLLLLLLLLLLLQPPPPTWALSPRISLPLGSEERPFL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 RFEAEHISNYTALLLSRDGRTLYVGAREALFALSSNLSFLPGGEYQELLWGADAEKKQQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFEAEHISNYTALLLSRDGRTLYVGAREALFALSSNLSFLPGGEYQELLWGADAEKKQQC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 SFKGKDPQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFKGKDPQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 GKGRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKGRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 VASAYIPESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQQRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VASAYIPESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQQRW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 TSFLKAQLLCSRPDDGFPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSFLKAQLLCSRPDDGFPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 FTMKDVQRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTMKDVQRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 NFLKDHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLHHTYDVLFLGTGDGRLHKAVSVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFLKDHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLHHTYDVLFLGTGDGRLHKAVSVG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 PRVHIIEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRVHIIEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 PYCAWSGSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSASSVVSPSFVPTGEKPCEQVQ
:::::::::::::::::::::::
NP_001 PYCAWSGSSCKHVSLYQPQLATRILSGPQAVDPGHRGSQRQGPLQRVFGCVPVFCTNRGE
550 560 570 580 590 600
>>NP_001310963 (OMIM: 617029) semaphorin-4B isoform 6 pr (847 aa)
initn: 3457 init1: 3457 opt: 3457 Z-score: 3562.0 bits: 670.1 E(85289): 1.2e-191
Smith-Waterman score: 5707; 98.8% identity (98.8% similar) in 847 aa overlap (1-837:1-847)
10 20 30 40 50 60
pF1KA1 MLRTAMGLRSWLAAPWGALPPRPPLLLLLLLLLLLQPPPPTWALSPRISLPLGSEERPFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLRTAMGLRSWLAAPWGALPPRPPLLLLLLLLLLLQPPPPTWALSPRISLPLGSEERPFL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 RFEAEHISNYTALLLSRDGRTLYVGAREALFALSSNLSFLPGGEYQELLWGADAEKKQQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFEAEHISNYTALLLSRDGRTLYVGAREALFALSSNLSFLPGGEYQELLWGADAEKKQQC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 SFKGKDPQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFKGKDPQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 GKGRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKGRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 VASAYIPESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQQRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VASAYIPESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQQRW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 TSFLKAQLLCSRPDDGFPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSFLKAQLLCSRPDDGFPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 FTMKDVQRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTMKDVQRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 NFLKDHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLHHTYDVLFLGTGDGRLHKAVSVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFLKDHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLHHTYDVLFLGTGDGRLHKAVSVG
430 440 450 460 470 480
490 500 510 520 530
pF1KA1 PRVHIIEELQIFSSGQPVQNLLLDTHR----------GLLYAASHSGVVQVPMANCSLYR
::::::::::::::::::::::::::: :::::::::::::::::::::::
NP_001 PRVHIIEELQIFSSGQPVQNLLLDTHRVSRPTRNPGRGLLYAASHSGVVQVPMANCSLYR
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 SCGDCLLARDPYCAWSGSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSASSVVSPSFVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCGDCLLARDPYCAWSGSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSASSVVSPSFVP
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 TGEKPCEQVQFQPNTVNTLACPLLSNLATRLWLRNGAPVNASASCHVLPTGDLLLVGTQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEKPCEQVQFQPNTVNTLACPLLSNLATRLWLRNGAPVNASASCHVLPTGDLLLVGTQQ
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 LGEFQCWSLEEGFQQLVASYCPEVVEDGVADQTDEGGSVPVIISTSRVSAPAGGKASWGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGEFQCWSLEEGFQQLVASYCPEVVEDGVADQTDEGGSVPVIISTSRVSAPAGGKASWGA
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 DRSYWKEFLVMCTLFVLAVLLPVLFLLYRHRNSMKVFLKQGECASVHPKTCPVVLPPETR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRSYWKEFLVMCTLFVLAVLLPVLFLLYRHRNSMKVFLKQGECASVHPKTCPVVLPPETR
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA1 PLNGLGPPSTPLDHRGYQSLSDSPPGSRVFTESEKRPLSIQDSFVEVSPVCPRPRVRLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLNGLGPPSTPLDHRGYQSLSDSPPGSRVFTESEKRPLSIQDSFVEVSPVCPRPRVRLGS
790 800 810 820 830 840
pF1KA1 EIRDSVV
:::::::
NP_001 EIRDSVV
>>NP_001310958 (OMIM: 617029) semaphorin-4B isoform 2 [H (699 aa)
initn: 3355 init1: 3355 opt: 3362 Z-score: 3465.2 bits: 651.9 E(85289): 2.8e-186
Smith-Waterman score: 3362; 92.3% identity (94.3% similar) in 543 aa overlap (297-837:161-699)
270 280 290 300 310 320
pF1KA1 TGQEFEFFENTIVSRIARICKGDEGGERVLQQRWT--SFLKAQLLCSRPDDGFPFNVLQD
: : .::.: :. :. .
NP_001 AASKGMTRPSRGAKAFAPPRPRAPSTGCKTQLLWPQPTFLRAWAACKAMMTRSTFSSARL
140 150 160 170 180 190
330 340 350 360 370 380
pF1KA1 VFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCVFTMKDVQRVFSGLYKEVNRETQQW
. .:: . : : .. .: ::::::::::::::::::::::::::::::::::::
NP_001 ARNLS----SLRTPLCPALPASARHRGTTEGSAVCVFTMKDVQRVFSGLYKEVNRETQQW
200 210 220 230 240
390 400 410 420 430 440
pF1KA1 YTVTHPVPTPRPGACITNSARERKINSSLQLPDRVLNFLKDHFLMDGQVRSRMLLLQPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTVTHPVPTPRPGACITNSARERKINSSLQLPDRVLNFLKDHFLMDGQVRSRMLLLQPQA
250 260 270 280 290 300
450 460 470 480 490 500
pF1KA1 RYQRVAVHRVPGLHHTYDVLFLGTGDGRLHKAVSVGPRVHIIEELQIFSSGQPVQNLLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYQRVAVHRVPGLHHTYDVLFLGTGDGRLHKAVSVGPRVHIIEELQIFSSGQPVQNLLLD
310 320 330 340 350 360
510 520 530 540 550 560
pF1KA1 THRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARDPYCAWSGSSCKHVSLYQPQLATRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 THRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARDPYCAWSGSSCKHVSLYQPQLATRP
370 380 390 400 410 420
570 580 590 600 610 620
pF1KA1 WIQDIEGASAKDLCSASSVVSPSFVPTGEKPCEQVQFQPNTVNTLACPLLSNLATRLWLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WIQDIEGASAKDLCSASSVVSPSFVPTGEKPCEQVQFQPNTVNTLACPLLSNLATRLWLR
430 440 450 460 470 480
630 640 650 660 670 680
pF1KA1 NGAPVNASASCHVLPTGDLLLVGTQQLGEFQCWSLEEGFQQLVASYCPEVVEDGVADQTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGAPVNASASCHVLPTGDLLLVGTQQLGEFQCWSLEEGFQQLVASYCPEVVEDGVADQTD
490 500 510 520 530 540
690 700 710 720 730 740
pF1KA1 EGGSVPVIISTSRVSAPAGGKASWGADRSYWKEFLVMCTLFVLAVLLPVLFLLYRHRNSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGGSVPVIISTSRVSAPAGGKASWGADRSYWKEFLVMCTLFVLAVLLPVLFLLYRHRNSM
550 560 570 580 590 600
750 760 770 780 790 800
pF1KA1 KVFLKQGECASVHPKTCPVVLPPETRPLNGLGPPSTPLDHRGYQSLSDSPPGSRVFTESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVFLKQGECASVHPKTCPVVLPPETRPLNGLGPPSTPLDHRGYQSLSDSPPGSRVFTESE
610 620 630 640 650 660
810 820 830
pF1KA1 KRPLSIQDSFVEVSPVCPRPRVRLGSEIRDSVV
:::::::::::::::::::::::::::::::::
NP_001 KRPLSIQDSFVEVSPVCPRPRVRLGSEIRDSVV
670 680 690
>>XP_011509685 (OMIM: 604462) PREDICTED: semaphorin-4C i (833 aa)
initn: 1268 init1: 436 opt: 1624 Z-score: 1672.2 bits: 320.4 E(85289): 2.1e-86
Smith-Waterman score: 1691; 40.7% identity (64.0% similar) in 761 aa overlap (42-787:25-736)
20 30 40 50 60 70
pF1KA1 LAAPWGALPPRPPLLLLLLLLLLLQPPPPTWALSPRISLPLGSEERPFLRFEAEHISNYT
: : :: .. : :: :...
XP_011 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFL
10 20 30 40 50
80 90 100 110 120 130
pF1KA1 ALLLSRDGRTLYVGAREALFALSSNLSFLPGGEYQELLWGADAEKKQQCSFKGKDPQRDC
.: :.. :::::::::::.: . : :. . : : .::: .: :::. : .:
XP_011 TLTLTEPTGLLYVGAREALFAFSMEALELQGA----ISWEAPVEKKTECIQKGKNNQTEC
60 70 80 90 100 110
140 150 160 170 180 190
pF1KA1 QNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLEDGKGRCPFDPNF
:.:..: : ..:::..::: ::.: :::.:: .::: :.:. .:::::.::.::
XP_011 FNFIRFLQPYNASHLYVCGTYAFQPKCTYVNMLTFTL---EHGE--FEDGKGKCPYDPAK
120 130 140 150 160
200 210 220 230 240 250
pF1KA1 KSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPT-KTESSLNWLQDPAFVASAYIPESL
..:.::::::..:...: :..: : :... . . ::: ::..: ::.:::.:::.
XP_011 GHAGLLVDGELYSATLNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESV
170 180 190 200 210 220
260 270 280 290 300 310
pF1KA1 GSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQQRWTSFLKAQLLC
::. :::::.:::: : . : . . . .:.:.::.:::: :: :.::..::.::::.: :
XP_011 GSFTGDDDKVYFFFRERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLAC
230 240 250 260 270 280
320 330 340 350 360 370
pF1KA1 SRPDDGFPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCVFTMKDVQRVF
: :. . :: :: . ::. . .:..: :.::: .:: : ::.: . ....::::
XP_011 SAPNWQLYFNQLQAMHTLQDT--SWHNTTFFGVFQAQW--GDMYLSAICEYQLEEIQRVF
290 300 310 320 330 340
380 390 400 410 420 430
pF1KA1 SGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVLNFLKDHFLMD
: ::: ..:.:.: : :::.::::.::.: :.. .:::.::: .:::.: : ::.
XP_011 EGPYKEYHEEAQKWDRYTDPVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLME
350 360 370 380 390 400
440 450 460 470 480
pF1KA1 GQVR---SRMLLLQPQARYQRVAVHRVPGLHH-TYDVLFLGTGDGRLHKAVSVGPRVHII
:: :: ::.. . . .... :: :: :: :::.::::: : ::::.:: ::.:
XP_011 EQVGPRWSRPLLVKKGTNFTHLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLI
410 420 430 440 450 460
490 500 510 520 530 540
pF1KA1 EELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARDPYCAWS
::::.:.. .:...:.:. . ::.:.:.: .::.:.:.: ::::.::.::::::::::
XP_011 EELQLFDQ-EPMRSLVLSQSKKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWS
470 480 490 500 510 520
550 560 570 580 590 600
pF1KA1 --GSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSASSVVSPSFVPTGEKPCEQVQFQPN
: : :. .. .: :: . .... .:. . : . :: : ... .
XP_011 VNTSRCVAVGGHSGSL----LIQHVMTSDTSGICNLRG--SKKVRPT---P-KNITVVAG
530 540 550 560 570
610 620 630 640 650
pF1KA1 TVNTLACPLLSNLATRLWLRNGAPVNASASCHVLPTGDL--LLVGTQQ---LGEFQCWSL
: .: : : :::: : .: . : : . : :.: . : : ..:.:
XP_011 TDLVLPCHLSSNLAHARWTFGGRDLPAEQPGSFLYDARLQALVVMAAQPRHAGAYHCFSE
580 590 600 610 620 630
660 670 680 690 700 710
pF1KA1 EEGFQQLVASYCPEVVEDGVADQTDEGGSVPVIISTSRVSAPAGGKASWGADRSYWKEFL
:.: . . .: :: : :: : .. :: . : :
XP_011 EQGARLAAEGYLVAVVA---------GPSV-----TLEARAPL---ENLGL---VW----
640 650 660
720 730 740 750 760 770
pF1KA1 VMCTLFVLAVLLPVLFLLYRHRNSMKVFLKQGECASVHPKTCPVVLP--PETRPLNGLGP
. .. . :: : .:.:. : .. :..: :. . . :. :: : . :.
XP_011 -LAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPFRPCPE
670 680 690 700 710 720
780 790 800 810 820 830
pF1KA1 PSTPL-DHRGYQSLSDSPPGSRVFTESEKRPLSIQDSFVEVSPVCPRPRVRLGSEIRDSV
:. : : ::
XP_011 PDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGGGRNSN
730 740 750 760 770 780
>>XP_011509680 (OMIM: 604462) PREDICTED: semaphorin-4C i (833 aa)
initn: 1268 init1: 436 opt: 1624 Z-score: 1672.2 bits: 320.4 E(85289): 2.1e-86
Smith-Waterman score: 1691; 40.7% identity (64.0% similar) in 761 aa overlap (42-787:25-736)
20 30 40 50 60 70
pF1KA1 LAAPWGALPPRPPLLLLLLLLLLLQPPPPTWALSPRISLPLGSEERPFLRFEAEHISNYT
: : :: .. : :: :...
XP_011 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFL
10 20 30 40 50
80 90 100 110 120 130
pF1KA1 ALLLSRDGRTLYVGAREALFALSSNLSFLPGGEYQELLWGADAEKKQQCSFKGKDPQRDC
.: :.. :::::::::::.: . : :. . : : .::: .: :::. : .:
XP_011 TLTLTEPTGLLYVGAREALFAFSMEALELQGA----ISWEAPVEKKTECIQKGKNNQTEC
60 70 80 90 100 110
140 150 160 170 180 190
pF1KA1 QNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLEDGKGRCPFDPNF
:.:..: : ..:::..::: ::.: :::.:: .::: :.:. .:::::.::.::
XP_011 FNFIRFLQPYNASHLYVCGTYAFQPKCTYVNMLTFTL---EHGE--FEDGKGKCPYDPAK
120 130 140 150 160
200 210 220 230 240 250
pF1KA1 KSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPT-KTESSLNWLQDPAFVASAYIPESL
..:.::::::..:...: :..: : :... . . ::: ::..: ::.:::.:::.
XP_011 GHAGLLVDGELYSATLNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESV
170 180 190 200 210 220
260 270 280 290 300 310
pF1KA1 GSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQQRWTSFLKAQLLC
::. :::::.:::: : . : . . . .:.:.::.:::: :: :.::..::.::::.: :
XP_011 GSFTGDDDKVYFFFRERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLAC
230 240 250 260 270 280
320 330 340 350 360 370
pF1KA1 SRPDDGFPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCVFTMKDVQRVF
: :. . :: :: . ::. . .:..: :.::: .:: : ::.: . ....::::
XP_011 SAPNWQLYFNQLQAMHTLQDT--SWHNTTFFGVFQAQW--GDMYLSAICEYQLEEIQRVF
290 300 310 320 330 340
380 390 400 410 420 430
pF1KA1 SGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVLNFLKDHFLMD
: ::: ..:.:.: : :::.::::.::.: :.. .:::.::: .:::.: : ::.
XP_011 EGPYKEYHEEAQKWDRYTDPVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLME
350 360 370 380 390 400
440 450 460 470 480
pF1KA1 GQVR---SRMLLLQPQARYQRVAVHRVPGLHH-TYDVLFLGTGDGRLHKAVSVGPRVHII
:: :: ::.. . . .... :: :: :: :::.::::: : ::::.:: ::.:
XP_011 EQVGPRWSRPLLVKKGTNFTHLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLI
410 420 430 440 450 460
490 500 510 520 530 540
pF1KA1 EELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARDPYCAWS
::::.:.. .:...:.:. . ::.:.:.: .::.:.:.: ::::.::.::::::::::
XP_011 EELQLFDQ-EPMRSLVLSQSKKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWS
470 480 490 500 510 520
550 560 570 580 590 600
pF1KA1 --GSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSASSVVSPSFVPTGEKPCEQVQFQPN
: : :. .. .: :: . .... .:. . : . :: : ... .
XP_011 VNTSRCVAVGGHSGSL----LIQHVMTSDTSGICNLRG--SKKVRPT---P-KNITVVAG
530 540 550 560 570
610 620 630 640 650
pF1KA1 TVNTLACPLLSNLATRLWLRNGAPVNASASCHVLPTGDL--LLVGTQQ---LGEFQCWSL
: .: : : :::: : .: . : : . : :.: . : : ..:.:
XP_011 TDLVLPCHLSSNLAHARWTFGGRDLPAEQPGSFLYDARLQALVVMAAQPRHAGAYHCFSE
580 590 600 610 620 630
660 670 680 690 700 710
pF1KA1 EEGFQQLVASYCPEVVEDGVADQTDEGGSVPVIISTSRVSAPAGGKASWGADRSYWKEFL
:.: . . .: :: : :: : .. :: . : :
XP_011 EQGARLAAEGYLVAVVA---------GPSV-----TLEARAPL---ENLGL---VW----
640 650 660
720 730 740 750 760 770
pF1KA1 VMCTLFVLAVLLPVLFLLYRHRNSMKVFLKQGECASVHPKTCPVVLP--PETRPLNGLGP
. .. . :: : .:.:. : .. :..: :. . . :. :: : . :.
XP_011 -LAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPFRPCPE
670 680 690 700 710 720
780 790 800 810 820 830
pF1KA1 PSTPL-DHRGYQSLSDSPPGSRVFTESEKRPLSIQDSFVEVSPVCPRPRVRLGSEIRDSV
:. : : ::
XP_011 PDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGGGRNSN
730 740 750 760 770 780
837 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 21:58:00 2016 done: Wed Nov 2 21:58:01 2016
Total Scan time: 10.430 Total Display time: 0.190
Function used was FASTA [36.3.4 Apr, 2011]