Result of FASTA (omim) for
pF1KA1139
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1139, 1202 aa
1>>>pF1KA1139 1202 - 1202 aa - 1202 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 18.2903+/-0.000559; mu= -36.5864+/- 0.035
mean_var=957.4467+/-197.300, 0's: 0 Z-trim(125.0): 320 B-trim: 0 in 0/62
Lambda= 0.041449
statistics sampled from 47489 (47905) to 47489 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.794), E-opt: 0.2 (0.562), width: 16
Scan time: 21.470
The best scores are: opt bits E(85289)
NP_065804 (OMIM: 612185) caskin-2 isoform a [Homo (1202) 8162 504.6 1.5e-141
NP_001136115 (OMIM: 612185) caskin-2 isoform b [Ho (1120) 7661 474.7 1.5e-132
NP_065815 (OMIM: 612184) caskin-1 [Homo sapiens] (1431) 1780 123.1 1.3e-26
XP_006719577 (OMIM: 607815) PREDICTED: ankyrin rep (1184) 700 58.4 3.2e-07
XP_016875147 (OMIM: 607815) PREDICTED: ankyrin rep (1188) 700 58.4 3.2e-07
XP_006719576 (OMIM: 607815) PREDICTED: ankyrin rep (1199) 700 58.4 3.2e-07
XP_006719575 (OMIM: 607815) PREDICTED: ankyrin rep (1200) 700 58.4 3.2e-07
XP_016875146 (OMIM: 607815) PREDICTED: ankyrin rep (1226) 700 58.4 3.2e-07
XP_006719573 (OMIM: 607815) PREDICTED: ankyrin rep (1235) 700 58.4 3.3e-07
NP_690001 (OMIM: 607815) ankyrin repeat and steril (1248) 700 58.4 3.3e-07
XP_016875145 (OMIM: 607815) PREDICTED: ankyrin rep (1250) 700 58.4 3.3e-07
XP_011536873 (OMIM: 607815) PREDICTED: ankyrin rep (1251) 700 58.4 3.3e-07
XP_005269086 (OMIM: 607815) PREDICTED: ankyrin rep (1256) 700 58.4 3.3e-07
XP_006719572 (OMIM: 607815) PREDICTED: ankyrin rep (1259) 700 58.4 3.3e-07
XP_016875144 (OMIM: 607815) PREDICTED: ankyrin rep (1259) 700 58.4 3.3e-07
XP_005269085 (OMIM: 607815) PREDICTED: ankyrin rep (1260) 700 58.4 3.3e-07
XP_006719571 (OMIM: 607815) PREDICTED: ankyrin rep (1260) 700 58.4 3.3e-07
XP_016875143 (OMIM: 607815) PREDICTED: ankyrin rep (1268) 700 58.4 3.3e-07
XP_016875142 (OMIM: 607815) PREDICTED: ankyrin rep (1272) 700 58.4 3.3e-07
XP_006719570 (OMIM: 607815) PREDICTED: ankyrin rep (1273) 700 58.4 3.3e-07
XP_016875141 (OMIM: 607815) PREDICTED: ankyrin rep (1281) 700 58.4 3.4e-07
XP_006719569 (OMIM: 607815) PREDICTED: ankyrin rep (1283) 700 58.4 3.4e-07
XP_006719567 (OMIM: 607815) PREDICTED: ankyrin rep (1284) 700 58.4 3.4e-07
XP_006719568 (OMIM: 607815) PREDICTED: ankyrin rep (1284) 700 58.4 3.4e-07
XP_016875140 (OMIM: 607815) PREDICTED: ankyrin rep (1285) 700 58.4 3.4e-07
NP_056060 (OMIM: 608994) ankyrin repeat and SAM do (1134) 672 56.7 9.8e-07
XP_011512737 (OMIM: 608994) PREDICTED: ankyrin rep (1144) 672 56.7 9.8e-07
XP_011512736 (OMIM: 608994) PREDICTED: ankyrin rep (1145) 672 56.7 9.8e-07
XP_011536691 (OMIM: 601234) PREDICTED: nascent pol (2078) 575 51.1 8.6e-05
XP_006719476 (OMIM: 601234) PREDICTED: nascent pol (2082) 575 51.1 8.6e-05
XP_006719475 (OMIM: 601234) PREDICTED: nascent pol (2082) 575 51.1 8.6e-05
XP_006719477 (OMIM: 601234) PREDICTED: nascent pol (2082) 575 51.1 8.6e-05
XP_011512738 (OMIM: 608994) PREDICTED: ankyrin rep (1100) 492 45.9 0.0017
XP_005249021 (OMIM: 608994) PREDICTED: ankyrin rep (1155) 492 46.0 0.0017
XP_006715099 (OMIM: 608994) PREDICTED: ankyrin rep (1156) 492 46.0 0.0017
XP_011512735 (OMIM: 608994) PREDICTED: ankyrin rep (1162) 492 46.0 0.0017
XP_011512734 (OMIM: 608994) PREDICTED: ankyrin rep (1165) 492 46.0 0.0017
XP_011512733 (OMIM: 608994) PREDICTED: ankyrin rep (1166) 492 46.0 0.0017
NP_006239 (OMIM: 168810) basic salivary proline-ri ( 416) 434 42.1 0.0088
>>NP_065804 (OMIM: 612185) caskin-2 isoform a [Homo sapi (1202 aa)
initn: 8162 init1: 8162 opt: 8162 Z-score: 2662.2 bits: 504.6 E(85289): 1.5e-141
Smith-Waterman score: 8162; 99.9% identity (99.9% similar) in 1202 aa overlap (1-1202:1-1202)
10 20 30 40 50 60
pF1KA1 MGREQDLILAVKNGDVTGVQKLVAKVKATKTKLLGSTKRLNVNYQDADGFSALHHAALGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MGREQDLILAVKNGDVTGVQKLVAKVKATKTKLLGSTKRLNVNYQDADGFSALHHAALGG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 SLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 LAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 AKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHEAALYGKTEVVRLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHEAALYGKTEVVRLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 LEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREASGILKVRALKDFWNLHDPTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREASGILKVRALKDFWNLHDPTA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 LNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVSKRVGIPAARLPSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVSKRVGIPAARLPSAP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 TPLRPGFSRTPQPPAEEPPHPLTYSQLPRVGLSPDSPAGDRNSVGSEGSVGSIRSAGSGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 TPLRPGFSRTPQPPAEEPPHPLTYSQLPRVGLSPDSPAGDRNSVGSEGSVGSIRSAGSGQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 SSEGTNGHGPGLLIENAQPLPSAGEDQVLPGLHPPSLADNLSHRPLANCRSGEQIFTQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SSEGTNGHGPGLLIENAQPLPSAGEDQVLPGLHPPSLADNLSHRPLANCRSGEQIFTQDV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 RPEQLLEGKDAQAIHNWLSEFQLEGYTAHFLQAGYDVPTISRMTPEDLTAIGVTKPGHRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RPEQLLEGKDAQAIHNWLSEFQLEGYTAHFLQAGYDVPTISRMTPEDLTAIGVTKPGHRK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 KIASEIAQLSIAEWLPSYIPTDLLEWLCALGLPQYHKQLVSSGYDSMGLVADLTWEELQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KIASEIAQLSIAEWLPSYIPTDLLEWLCALGLPQYHKQLVSSGYDSMGLVADLTWEELQE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 IGVNKLGHQKKLMLGVKRLAELRRGLLQGEALSEGGRRLAKGPELMAIEGLENGEGPATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 IGVNKLGHQKKLMLGVKRLAELRRGLLQGEALSEGGRRLAKGPELMAIEGLENGEGPATA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 GPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 GGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSY
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 LAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 TSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDGSPGPKEGAT
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
NP_065 TSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGAT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 GPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 KQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 PLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWN
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA1 GETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVG
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA1 PGQAQQRLEQTSSSLAAALRAAEKSIGTKEQEGTPSASTKHILDDISTMFDALADQLDAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PGQAQQRLEQTSSSLAAALRAAEKSIGTKEQEGTPSASTKHILDDISTMFDALADQLDAM
1150 1160 1170 1180 1190 1200
pF1KA1 LD
::
NP_065 LD
>>NP_001136115 (OMIM: 612185) caskin-2 isoform b [Homo s (1120 aa)
initn: 7661 init1: 7661 opt: 7661 Z-score: 2500.7 bits: 474.7 E(85289): 1.5e-132
Smith-Waterman score: 7661; 99.9% identity (99.9% similar) in 1120 aa overlap (83-1202:1-1120)
60 70 80 90 100 110
pF1KA1 LHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAAS
::::::::::::::::::::::::::::::
NP_001 MRPLHYAAWQGRLEPVRLLLRASAAVNAAS
10 20 30
120 130 140 150 160 170
pF1KA1 LDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHL
40 50 60 70 80 90
180 190 200 210 220 230
pF1KA1 CVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHEAALYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHEAALYG
100 110 120 130 140 150
240 250 260 270 280 290
pF1KA1 KTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREASGILKVRALKDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREASGILKVRALKDF
160 170 180 190 200 210
300 310 320 330 340 350
pF1KA1 WNLHDPTALNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVSKRVGIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WNLHDPTALNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVSKRVGIP
220 230 240 250 260 270
360 370 380 390 400 410
pF1KA1 AARLPSAPTPLRPGFSRTPQPPAEEPPHPLTYSQLPRVGLSPDSPAGDRNSVGSEGSVGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AARLPSAPTPLRPGFSRTPQPPAEEPPHPLTYSQLPRVGLSPDSPAGDRNSVGSEGSVGS
280 290 300 310 320 330
420 430 440 450 460 470
pF1KA1 IRSAGSGQSSEGTNGHGPGLLIENAQPLPSAGEDQVLPGLHPPSLADNLSHRPLANCRSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRSAGSGQSSEGTNGHGPGLLIENAQPLPSAGEDQVLPGLHPPSLADNLSHRPLANCRSG
340 350 360 370 380 390
480 490 500 510 520 530
pF1KA1 EQIFTQDVRPEQLLEGKDAQAIHNWLSEFQLEGYTAHFLQAGYDVPTISRMTPEDLTAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQIFTQDVRPEQLLEGKDAQAIHNWLSEFQLEGYTAHFLQAGYDVPTISRMTPEDLTAIG
400 410 420 430 440 450
540 550 560 570 580 590
pF1KA1 VTKPGHRKKIASEIAQLSIAEWLPSYIPTDLLEWLCALGLPQYHKQLVSSGYDSMGLVAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTKPGHRKKIASEIAQLSIAEWLPSYIPTDLLEWLCALGLPQYHKQLVSSGYDSMGLVAD
460 470 480 490 500 510
600 610 620 630 640 650
pF1KA1 LTWEELQEIGVNKLGHQKKLMLGVKRLAELRRGLLQGEALSEGGRRLAKGPELMAIEGLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTWEELQEIGVNKLGHQKKLMLGVKRLAELRRGLLQGEALSEGGRRLAKGPELMAIEGLE
520 530 540 550 560 570
660 670 680 690 700 710
pF1KA1 NGEGPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGEGPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQ
580 590 600 610 620 630
720 730 740 750 760 770
pF1KA1 EQPAPQPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQPAPQPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPP
640 650 660 670 680 690
780 790 800 810 820 830
pF1KA1 GAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRR
700 710 720 730 740 750
840 850 860 870 880 890
pF1KA1 PGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDGS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_001 PGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDES
760 770 780 790 800 810
900 910 920 930 940 950
pF1KA1 PGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPF
820 830 840 850 860 870
960 970 980 990 1000 1010
pF1KA1 AEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVA
880 890 900 910 920 930
1020 1030 1040 1050 1060 1070
pF1KA1 SATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLE
940 950 960 970 980 990
1080 1090 1100 1110 1120 1130
pF1KA1 SSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPR
1000 1010 1020 1030 1040 1050
1140 1150 1160 1170 1180 1190
pF1KA1 PESTGTVGPGQAQQRLEQTSSSLAAALRAAEKSIGTKEQEGTPSASTKHILDDISTMFDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PESTGTVGPGQAQQRLEQTSSSLAAALRAAEKSIGTKEQEGTPSASTKHILDDISTMFDA
1060 1070 1080 1090 1100 1110
1200
pF1KA1 LADQLDAMLD
::::::::::
NP_001 LADQLDAMLD
1120
>>NP_065815 (OMIM: 612184) caskin-1 [Homo sapiens] (1431 aa)
initn: 2685 init1: 1651 opt: 1780 Z-score: 598.6 bits: 123.1 E(85289): 1.3e-26
Smith-Waterman score: 2810; 44.4% identity (62.0% similar) in 1267 aa overlap (1-1067:1-1230)
10 20 30 40 50 60
pF1KA1 MGREQDLILAVKNGDVTGVQKLVAKVKATKTKLLGSTKRLNVNYQDADGFSALHHAALGG
::.::.:. ::: :: .:.:. . . :.:::::::..:::.:: :::::::::::.:
NP_065 MGKEQELVQAVKAEDVGTAQRLLQRPRPGKAKLLGSTKKINVNFQDPDGFSALHHAALNG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 SLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLH
. :::.:::::::.:::::..::::::::::::: ::..:.:.:..::: : .:.::::
NP_065 NTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNIPSDEGHIPLH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 LAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGE
::::.:::.:::::::::::::.:... ::::::::::::. :.::::.:..:.:::: .
NP_065 LAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 AKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHEAALYGKTEVVRLL
: ::: :.:::::::::: ..:: ::.:::.::::::.::::::::: :::::::::
NP_065 PGDATDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSGTALHEAALCGKTEVVRLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 LEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREASGILKVRALKDFWNLHDPTA
:..:.....::::.:::::::.:::::::::::::::::::. :.::: ::. : .: :.
NP_065 LDSGINAHVRNTYSQTALDIVHQFTTSQASREIKQLLREASAALQVRATKDYCNNYDLTS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 LNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVSKRVGIPAARLPSAP
:::.:::.:::::::::::::: ::... :.::.:::: .. :.. ::.: :. :: :
NP_065 LNVKAGDIITVLEQHPDGRWKGCIHDNRTGNDRVGYFPSSLGEAIVKRAGSRAGTEPSLP
310 320 330 340 350 360
370 380 390 400 410
pF1KA1 TPLRPGFSRTPQPPAEEPPHPLTYSQLPRVGL----SPDSPAGDRNSVGSEGSVGS--IR
: : . : : ::. . . : .: : .. :: :.: : .:: ..
NP_065 Q----G-SSSSGPSA--PPEEIWVLRKPFAGGDRSGSISGMAGGRGSGGHALHAGSEGVK
370 380 390 400 410
420 430 440 450 460 470
pF1KA1 SAGSGQSSEGTNGHGPGLLIENAQPLPSAGEDQVLPGLHPPSLADNLSHRPLANCRSGEQ
.. :..... ::: .. : : : . .:: ..: :. :::
NP_065 LLATVLSQKSVSESGPG----DSPAKPPEGSAGVARS-QPP-----VAH---AGQVYGEQ
420 430 440 450 460
480 490 500 510 520 530
pF1KA1 IFTQDVRPEQLLEGKDAQAIHNWLSEFQLEGYTAHFLQAGYDVPTISRMTPEDLTAIGVT
. ..: . :::...:. .::. :::. :. .:..::::.:::::::::::::::::
NP_065 P-PKKLEPAS--EGKSSEAVSQWLTAFQLQLYAPNFISAGYDLPTISRMTPEDLTAIGVT
470 480 490 500 510
540 550 560 570 580 590
pF1KA1 KPGHRKKIASEIAQLSIAEWLPSYIPTDLLEWLCALGLPQYHKQLVSSGYDSMGLVADLT
:::::::::.::. ::: .::: . :..: :: .:: ::.: ::..::... ...:.:
NP_065 KPGHRKKIAAEISGLSIPDWLPEHKPANLAVWLSMIGLAQYYKVLVDNGYENIDFITDIT
520 530 540 550 560 570
600 610 620 630 640 650
pF1KA1 WEELQEIGVNKLGHQKKLMLGVKRLAELRRGLLQGEALSEGGRRLAKGP---ELMAIEGL
::.:::::..::::::::::.:..::::... : ::: :.: :.::::.
NP_065 WEDLQEIGITKLGHQKKLMLAVRKLAELQKAEY---AKYEGGPLRRKAPQSLEVMAIESP
580 590 600 610 620 630
660 670 680 690 700
pF1KA1 ENGEG-PATA-GPRLLTFQGSELSPELQAAMAGG---GP---EP---LPLPPARSPSQES
: :: .:.. ::: :::: ::::::.: :: .: :: : . :.:
NP_065 PPPEPTPADCQSPKMTTFQDSELSDELQAAMTGPAEVGPTTEKPSSHLPPTPRATTRQDS
640 650 660 670 680 690
710 720
pF1KA1 -IGARSRGSGHSQE-----QPAPQ--------------PSGGDPS---------------
.:.:.: . ::: :.:. :. : :
NP_065 SLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPAPGTPPREARPGRHGHSIKRA
700 710 720 730 740 750
730 740 750
pF1KA1 --PP---QERN-LPEGTER--PPKL-CSSLPG--------QGPPPYVF------------
:: . :. :: :: . ::. .. :: .:: : .
NP_065 SVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPT
760 770 780 790 800 810
760 770 780 790
pF1KA1 ---MYPQGSPSSP--------------------APGP-PPGAPWAFSYLAGPPATPPDPP
: :.. :.:: :::: :: .: : : :: . .:
NP_065 ERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPVPTAVPTLCLPPEADAEPG
820 830 840 850 860 870
800 810 820 830 840 850
pF1KA1 RPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPA-R
:::.:.:::.: . .... : . : : .. : :::. :: ::: ::. :. : .
NP_065 RPKKRAHSLNRYAASDSEPERD-ELLVPAAAGPYATVQRRVGRSHSVRA-----PAGADK
880 890 900 910 920
860 870 880 890
pF1KA1 GTPRSQSFALRARRKGPPPPPPKRLSSVSG-------PSPEPPPLDGSPGPKE-------
.. ::::::.: :.:::::::::: ::. . : :. : :: : .
NP_065 NVNRSQSFAVRPRKKGPPPPPPKRSSSALASANLADEPVPDAEPEDGLLGVRAQCRRASD
930 940 950 960 970 980
900 910 920
pF1KA1 -------GATGPRRRT-----LSEPAG-------PSEPPGPPAPAGP---------ASDT
:..: . :: .: : : : ::.: ::
NP_065 LAGSVDTGSAGSVKSIAAMLELSSIGGGGRAARRPPEGHPTPRPASPEPGRVATVLASVK
990 1000 1010 1020 1030 1040
930 940 950 960 970
pF1KA1 EEEEPGPEGTPPSR-------------------GSSGEGLPFAEEGNLTIKQRPKPAGPP
..: :: : .: : :.. ::.:.: : .:::. ::
NP_065 HKEAIGPGGEVVNRRRTLSGPVTGLLATARRGPGESADPGPFVEDG--TGRQRPR--GPS
1050 1060 1070 1080 1090 1100
980 990 1000
pF1KA1 PRETPV--PP----------------------GLDFNLTESDTVKRRPKCRERE-----P
:. : :: .. : :::::::::::: .::: :
NP_065 KGEAGVEGPPLAKVEASATLKRRIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPP
1110 1120 1130 1140 1150 1160
1010 1020 1030 1040 1050 1060
pF1KA1 LQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEP-SSLPAQGVPTPLAPSPAMQ
.. :.... ::. .: :: . : : . :: : : .:: .
NP_065 PPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPA-K
1170 1180 1190 1200 1210 1220
1070 1080 1090 1100 1110 1120
pF1KA1 PPVPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLA
::: : :
NP_065 PPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKP
1230 1240 1250 1260 1270 1280
>>XP_006719577 (OMIM: 607815) PREDICTED: ankyrin repeat (1184 aa)
initn: 853 init1: 293 opt: 700 Z-score: 250.7 bits: 58.4 E(85289): 3.2e-07
Smith-Waterman score: 700; 39.0% identity (71.5% similar) in 305 aa overlap (1-291:1-296)
10 20 30 40 50
pF1KA1 MGREQDLILAVKNGDVTGVQKLVAKVKA----------TKTKLLGSTKRLNVNYQDADGF
::..:.:. :...:.:. :.::.. :. ..::. . ::: :..:.
XP_006 MGKDQELLEAARTGNVALVEKLLSGRKGGILGGGSGPLPLSNLLSIWRGPNVNCTDSSGY
10 20 30 40 50 60
60 70 80 90 100
pF1KA1 SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLR---ASAA
.:::::::.: ... ::. .:.... :..:. :.: :::.: .: :..:.. . .
XP_006 TALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 VNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLL
:: . ... :: :::::: :: .::.. ..: . :. .:::::: .:::.:....
XP_006 VNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMI
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 LNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHE
...: :. :. :::::::.:::. :.. ::.::.... ::. :.::::
XP_006 ISAH--PNLMS------CNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGSALHE
190 200 210 220 230
230 240 250 260 270 280
pF1KA1 AALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREA-SGILKV
:::.::..:::.::: :.:.::... ..:.:::... :: : .: ::.: :. .
XP_006 AALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHP-SQKSLQIATLLQEYLEGVGRS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KA1 RALKDFWNLHDPTALNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVS
.:..
XP_006 TVLEEPVQEDATQETHISSPVESPSQKTKSETVTGELSKLLDEIKLCQEKDYSFEDLCHT
300 310 320 330 340 350
>>XP_016875147 (OMIM: 607815) PREDICTED: ankyrin repeat (1188 aa)
initn: 853 init1: 293 opt: 700 Z-score: 250.7 bits: 58.4 E(85289): 3.2e-07
Smith-Waterman score: 700; 39.0% identity (71.5% similar) in 305 aa overlap (1-291:1-296)
10 20 30 40 50
pF1KA1 MGREQDLILAVKNGDVTGVQKLVAKVKA----------TKTKLLGSTKRLNVNYQDADGF
::..:.:. :...:.:. :.::.. :. ..::. . ::: :..:.
XP_016 MGKDQELLEAARTGNVALVEKLLSGRKGGILGGGSGPLPLSNLLSIWRGPNVNCTDSSGY
10 20 30 40 50 60
60 70 80 90 100
pF1KA1 SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLR---ASAA
.:::::::.: ... ::. .:.... :..:. :.: :::.: .: :..:.. . .
XP_016 TALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 VNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLL
:: . ... :: :::::: :: .::.. ..: . :. .:::::: .:::.:....
XP_016 VNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMI
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 LNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHE
...: :. :. :::::::.:::. :.. ::.::.... ::. :.::::
XP_016 ISAH--PNLMS------CNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGSALHE
190 200 210 220 230
230 240 250 260 270 280
pF1KA1 AALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREA-SGILKV
:::.::..:::.::: :.:.::... ..:.:::... :: : .: ::.: :. .
XP_016 AALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHP-SQKSLQIATLLQEYLEGVGRS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KA1 RALKDFWNLHDPTALNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVS
.:..
XP_016 TVLEEPVQEDATQETHISSPVESPSQKTKSETVTGELSKLLDEIKLCQEKDYSFEDLCHT
300 310 320 330 340 350
>>XP_006719576 (OMIM: 607815) PREDICTED: ankyrin repeat (1199 aa)
initn: 853 init1: 293 opt: 700 Z-score: 250.6 bits: 58.4 E(85289): 3.2e-07
Smith-Waterman score: 700; 39.0% identity (71.5% similar) in 305 aa overlap (1-291:1-296)
10 20 30 40 50
pF1KA1 MGREQDLILAVKNGDVTGVQKLVAKVKA----------TKTKLLGSTKRLNVNYQDADGF
::..:.:. :...:.:. :.::.. :. ..::. . ::: :..:.
XP_006 MGKDQELLEAARTGNVALVEKLLSGRKGGILGGGSGPLPLSNLLSIWRGPNVNCTDSSGY
10 20 30 40 50 60
60 70 80 90 100
pF1KA1 SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLR---ASAA
.:::::::.: ... ::. .:.... :..:. :.: :::.: .: :..:.. . .
XP_006 TALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 VNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLL
:: . ... :: :::::: :: .::.. ..: . :. .:::::: .:::.:....
XP_006 VNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMI
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 LNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHE
...: :. :. :::::::.:::. :.. ::.::.... ::. :.::::
XP_006 ISAH--PNLMS------CNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGSALHE
190 200 210 220 230
230 240 250 260 270 280
pF1KA1 AALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREA-SGILKV
:::.::..:::.::: :.:.::... ..:.:::... :: : .: ::.: :. .
XP_006 AALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHP-SQKSLQIATLLQEYLEGVGRS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KA1 RALKDFWNLHDPTALNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVS
.:..
XP_006 TVLEEPVQEDATQETHISSPVESPSQKTKSETVTGELSKLLDEIKLCQEKDYSFEDLCHT
300 310 320 330 340 350
>>XP_006719575 (OMIM: 607815) PREDICTED: ankyrin repeat (1200 aa)
initn: 853 init1: 293 opt: 700 Z-score: 250.6 bits: 58.4 E(85289): 3.2e-07
Smith-Waterman score: 700; 39.0% identity (71.5% similar) in 305 aa overlap (1-291:1-296)
10 20 30 40 50
pF1KA1 MGREQDLILAVKNGDVTGVQKLVAKVKA----------TKTKLLGSTKRLNVNYQDADGF
::..:.:. :...:.:. :.::.. :. ..::. . ::: :..:.
XP_006 MGKDQELLEAARTGNVALVEKLLSGRKGGILGGGSGPLPLSNLLSIWRGPNVNCTDSSGY
10 20 30 40 50 60
60 70 80 90 100
pF1KA1 SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLR---ASAA
.:::::::.: ... ::. .:.... :..:. :.: :::.: .: :..:.. . .
XP_006 TALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 VNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLL
:: . ... :: :::::: :: .::.. ..: . :. .:::::: .:::.:....
XP_006 VNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMI
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 LNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHE
...: :. :. :::::::.:::. :.. ::.::.... ::. :.::::
XP_006 ISAH--PNLMS------CNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGSALHE
190 200 210 220 230
230 240 250 260 270 280
pF1KA1 AALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREA-SGILKV
:::.::..:::.::: :.:.::... ..:.:::... :: : .: ::.: :. .
XP_006 AALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHP-SQKSLQIATLLQEYLEGVGRS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KA1 RALKDFWNLHDPTALNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVS
.:..
XP_006 TVLEEPVQEDATQETHISSPVESPSQKTKSETVTGELSKLLDEIKLCQEKDYSFEDLCHT
300 310 320 330 340 350
>>XP_016875146 (OMIM: 607815) PREDICTED: ankyrin repeat (1226 aa)
initn: 853 init1: 293 opt: 700 Z-score: 250.5 bits: 58.4 E(85289): 3.2e-07
Smith-Waterman score: 700; 39.0% identity (71.5% similar) in 305 aa overlap (1-291:1-296)
10 20 30 40 50
pF1KA1 MGREQDLILAVKNGDVTGVQKLVAKVKA----------TKTKLLGSTKRLNVNYQDADGF
::..:.:. :...:.:. :.::.. :. ..::. . ::: :..:.
XP_016 MGKDQELLEAARTGNVALVEKLLSGRKGGILGGGSGPLPLSNLLSIWRGPNVNCTDSSGY
10 20 30 40 50 60
60 70 80 90 100
pF1KA1 SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLR---ASAA
.:::::::.: ... ::. .:.... :..:. :.: :::.: .: :..:.. . .
XP_016 TALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 VNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLL
:: . ... :: :::::: :: .::.. ..: . :. .:::::: .:::.:....
XP_016 VNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMI
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 LNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHE
...: :. :. :::::::.:::. :.. ::.::.... ::. :.::::
XP_016 ISAH--PNLMS------CNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGSALHE
190 200 210 220 230
230 240 250 260 270 280
pF1KA1 AALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREA-SGILKV
:::.::..:::.::: :.:.::... ..:.:::... :: : .: ::.: :. .
XP_016 AALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHP-SQKSLQIATLLQEYLEGVGRS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KA1 RALKDFWNLHDPTALNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVS
.:..
XP_016 TVLEEPVQEDATQETHISSPVESPSQKTKSETVTGELSKLLDEIKLCQEKDYSFEDLCHT
300 310 320 330 340 350
>>XP_006719573 (OMIM: 607815) PREDICTED: ankyrin repeat (1235 aa)
initn: 853 init1: 293 opt: 700 Z-score: 250.5 bits: 58.4 E(85289): 3.3e-07
Smith-Waterman score: 700; 39.0% identity (71.5% similar) in 305 aa overlap (1-291:1-296)
10 20 30 40 50
pF1KA1 MGREQDLILAVKNGDVTGVQKLVAKVKA----------TKTKLLGSTKRLNVNYQDADGF
::..:.:. :...:.:. :.::.. :. ..::. . ::: :..:.
XP_006 MGKDQELLEAARTGNVALVEKLLSGRKGGILGGGSGPLPLSNLLSIWRGPNVNCTDSSGY
10 20 30 40 50 60
60 70 80 90 100
pF1KA1 SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLR---ASAA
.:::::::.: ... ::. .:.... :..:. :.: :::.: .: :..:.. . .
XP_006 TALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 VNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLL
:: . ... :: :::::: :: .::.. ..: . :. .:::::: .:::.:....
XP_006 VNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMI
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 LNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHE
...: :. :. :::::::.:::. :.. ::.::.... ::. :.::::
XP_006 ISAH--PNLMS------CNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGSALHE
190 200 210 220 230
230 240 250 260 270 280
pF1KA1 AALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREA-SGILKV
:::.::..:::.::: :.:.::... ..:.:::... :: : .: ::.: :. .
XP_006 AALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHP-SQKSLQIATLLQEYLEGVGRS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KA1 RALKDFWNLHDPTALNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVS
.:..
XP_006 TVLEEPVQEDATQETHISSPVESPSQKTKSETVTGELSKLLDEIKLCQEKDYSFEDLCHT
300 310 320 330 340 350
>>NP_690001 (OMIM: 607815) ankyrin repeat and sterile al (1248 aa)
initn: 853 init1: 293 opt: 700 Z-score: 250.4 bits: 58.4 E(85289): 3.3e-07
Smith-Waterman score: 700; 39.0% identity (71.5% similar) in 305 aa overlap (1-291:1-296)
10 20 30 40 50
pF1KA1 MGREQDLILAVKNGDVTGVQKLVAKVKA----------TKTKLLGSTKRLNVNYQDADGF
::..:.:. :...:.:. :.::.. :. ..::. . ::: :..:.
NP_690 MGKDQELLEAARTGNVALVEKLLSGRKGGILGGGSGPLPLSNLLSIWRGPNVNCTDSSGY
10 20 30 40 50 60
60 70 80 90 100
pF1KA1 SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLR---ASAA
.:::::::.: ... ::. .:.... :..:. :.: :::.: .: :..:.. . .
NP_690 TALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 VNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLL
:: . ... :: :::::: :: .::.. ..: . :. .:::::: .:::.:....
NP_690 VNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMI
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 LNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHE
...: :. :. :::::::.:::. :.. ::.::.... ::. :.::::
NP_690 ISAH--PNLMS------CNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGSALHE
190 200 210 220 230
230 240 250 260 270 280
pF1KA1 AALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREA-SGILKV
:::.::..:::.::: :.:.::... ..:.:::... :: : .: ::.: :. .
NP_690 AALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHP-SQKSLQIATLLQEYLEGVGRS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KA1 RALKDFWNLHDPTALNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVS
.:..
NP_690 TVLEEPVQEDATQETHISSPVESPSQKTKSETVTGELSKLLDEIKLCQEKDYSFEDLCHT
300 310 320 330 340 350
1202 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 01:21:20 2016 done: Fri Nov 4 01:21:23 2016
Total Scan time: 21.470 Total Display time: 0.290
Function used was FASTA [36.3.4 Apr, 2011]