Result of FASTA (omim) for
pF1KA0460
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0460, 1424 aa
1>>>pF1KA0460 1424 - 1424 aa - 1424 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.9347+/-0.000504; mu= -26.2106+/- 0.031
mean_var=666.2414+/-139.245, 0's: 0 Z-trim(123.3): 56 B-trim: 1443 in 1/61
Lambda= 0.049689
statistics sampled from 42885 (42952) to 42885 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.504), width: 16
Scan time: 18.960
The best scores are: opt bits E(85289)
NP_056018 (OMIM: 614695) regulation of nuclear pre (1461) 9503 697.6 1.8e-199
XP_016856253 (OMIM: 614695) PREDICTED: regulation (1325) 8823 648.8 7.8e-185
NP_001284603 (OMIM: 614695) regulation of nuclear (1435) 8620 634.3 2e-180
XP_016856252 (OMIM: 614695) PREDICTED: regulation (1368) 6358 472.1 1.2e-131
XP_011507646 (OMIM: 614695) PREDICTED: regulation (1394) 6358 472.1 1.3e-131
XP_006711303 (OMIM: 614695) PREDICTED: regulation ( 960) 5779 430.5 2.9e-119
NP_001284602 (OMIM: 614695) regulation of nuclear ( 934) 4896 367.2 3.3e-100
XP_005245090 (OMIM: 614695) PREDICTED: regulation ( 706) 4087 309.1 7.5e-83
XP_016856255 (OMIM: 614695) PREDICTED: regulation ( 680) 3204 245.8 8.3e-64
XP_016856254 (OMIM: 614695) PREDICTED: regulation ( 893) 2882 222.8 9.1e-57
XP_016856256 (OMIM: 614695) PREDICTED: regulation ( 613) 1964 156.9 4.4e-37
>>NP_056018 (OMIM: 614695) regulation of nuclear pre-mRN (1461 aa)
initn: 9503 init1: 9503 opt: 9503 Z-score: 3702.2 bits: 697.6 E(85289): 1.8e-199
Smith-Waterman score: 9503; 100.0% identity (100.0% similar) in 1424 aa overlap (1-1424:38-1461)
10 20 30
pF1KA0 MESIQGLSSWCIENKKHHSTIVYHWMKWLR
::::::::::::::::::::::::::::::
NP_056 GSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KA0 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA0 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA0 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA0 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA0 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA0 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
730 740 750 760 770 780
760 770 780 790 800 810
pF1KA0 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
790 800 810 820 830 840
820 830 840 850 860 870
pF1KA0 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
850 860 870 880 890 900
880 890 900 910 920 930
pF1KA0 SSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPH
910 920 930 940 950 960
940 950 960 970 980 990
pF1KA0 PVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFG
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KA0 QAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIET
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KA0 LGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASE
1090 1100 1110 1120 1130 1140
1120 1130 1140 1150 1160 1170
pF1KA0 LASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQR
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210 1220 1230
pF1KA0 EPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPF
1210 1220 1230 1240 1250 1260
1240 1250 1260 1270 1280 1290
pF1KA0 PTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKD
1270 1280 1290 1300 1310 1320
1300 1310 1320 1330 1340 1350
pF1KA0 HSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHGGGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHGGGG
1330 1340 1350 1360 1370 1380
1360 1370 1380 1390 1400 1410
pF1KA0 GGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGP
1390 1400 1410 1420 1430 1440
1420
pF1KA0 PFFAPKRPFFPPRY
::::::::::::::
NP_056 PFFAPKRPFFPPRY
1450 1460
>>XP_016856253 (OMIM: 614695) PREDICTED: regulation of n (1325 aa)
initn: 8823 init1: 8823 opt: 8823 Z-score: 3439.3 bits: 648.8 E(85289): 7.8e-185
Smith-Waterman score: 8823; 100.0% identity (100.0% similar) in 1325 aa overlap (100-1424:1-1325)
70 80 90 100 110 120
pF1KA0 AAALVKDPSVSKSVERIFKIWEDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQ
::::::::::::::::::::::::::::::
XP_016 MIVALREALSTTFKTQKQLKENLNKQPNKQ
10 20 30
130 140 150 160 170 180
pF1KA0 WKKSQTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WKKSQTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTET
40 50 60 70 80 90
190 200 210 220 230 240
pF1KA0 LKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVK
100 110 120 130 140 150
250 260 270 280 290 300
pF1KA0 VVANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEES
160 170 180 190 200 210
310 320 330 340 350 360
pF1KA0 QSPTMESEKSATPEPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSPTMESEKSATPEPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKP
220 230 240 250 260 270
370 380 390 400 410 420
pF1KA0 TENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSV
280 290 300 310 320 330
430 440 450 460 470 480
pF1KA0 MKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALS
340 350 360 370 380 390
490 500 510 520 530 540
pF1KA0 KTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFI
400 410 420 430 440 450
550 560 570 580 590 600
pF1KA0 PKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEV
460 470 480 490 500 510
610 620 630 640 650 660
pF1KA0 TICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPS
520 530 540 550 560 570
670 680 690 700 710 720
pF1KA0 DFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSS
580 590 600 610 620 630
730 740 750 760 770 780
pF1KA0 TRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTS
640 650 660 670 680 690
790 800 810 820 830 840
pF1KA0 FQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVK
700 710 720 730 740 750
850 860 870 880 890 900
pF1KA0 SAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNS
760 770 780 790 800 810
910 920 930 940 950 960
pF1KA0 LSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTST
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KA0 IEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETR
880 890 900 910 920 930
1030 1040 1050 1060 1070 1080
pF1KA0 VSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRV
940 950 960 970 980 990
1090 1100 1110 1120 1130 1140
pF1KA0 GWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSF
1000 1010 1020 1030 1040 1050
1150 1160 1170 1180 1190 1200
pF1KA0 NSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTK
1060 1070 1080 1090 1100 1110
1210 1220 1230 1240 1250 1260
pF1KA0 EAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVP
1120 1130 1140 1150 1160 1170
1270 1280 1290 1300 1310 1320
pF1KA0 FPAPPLAEHGVAGAVAVFPKDHSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPAPPLAEHGVAGAVAVFPKDHSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVR
1180 1190 1200 1210 1220 1230
1330 1340 1350 1360 1370 1380
pF1KA0 ESLTLPSHSLEHLGPPHGGGGGGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESLTLPSHSLEHLGPPHGGGGGGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREP
1240 1250 1260 1270 1280 1290
1390 1400 1410 1420
pF1KA0 FLSRDPFHSLKRPRPPFARGPPFFAPKRPFFPPRY
:::::::::::::::::::::::::::::::::::
XP_016 FLSRDPFHSLKRPRPPFARGPPFFAPKRPFFPPRY
1300 1310 1320
>>NP_001284603 (OMIM: 614695) regulation of nuclear pre- (1435 aa)
initn: 8604 init1: 8604 opt: 8620 Z-score: 3360.2 bits: 634.3 E(85289): 2e-180
Smith-Waterman score: 9269; 98.2% identity (98.2% similar) in 1424 aa overlap (1-1424:38-1435)
10 20 30
pF1KA0 MESIQGLSSWCIENKKHHSTIVYHWMKWLR
::::::::::::::::::::::::::::::
NP_001 GSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KA0 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
:::::::::::::::::: ::::::::::::::::
NP_001 EDRNVYPEEMIVALREAL--------------------------TSTNPKAALKSKIVAE
130 140 150 160
160 170 180 190 200 210
pF1KA0 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
170 180 190 200 210 220
220 230 240 250 260 270
pF1KA0 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
230 240 250 260 270 280
280 290 300 310 320 330
pF1KA0 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
290 300 310 320 330 340
340 350 360 370 380 390
pF1KA0 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
350 360 370 380 390 400
400 410 420 430 440 450
pF1KA0 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
410 420 430 440 450 460
460 470 480 490 500 510
pF1KA0 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
470 480 490 500 510 520
520 530 540 550 560 570
pF1KA0 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
530 540 550 560 570 580
580 590 600 610 620 630
pF1KA0 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
590 600 610 620 630 640
640 650 660 670 680 690
pF1KA0 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
650 660 670 680 690 700
700 710 720 730 740 750
pF1KA0 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
710 720 730 740 750 760
760 770 780 790 800 810
pF1KA0 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
770 780 790 800 810 820
820 830 840 850 860 870
pF1KA0 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
830 840 850 860 870 880
880 890 900 910 920 930
pF1KA0 SSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPH
890 900 910 920 930 940
940 950 960 970 980 990
pF1KA0 PVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFG
950 960 970 980 990 1000
1000 1010 1020 1030 1040 1050
pF1KA0 QAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIET
1010 1020 1030 1040 1050 1060
1060 1070 1080 1090 1100 1110
pF1KA0 LGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASE
1070 1080 1090 1100 1110 1120
1120 1130 1140 1150 1160 1170
pF1KA0 LASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQR
1130 1140 1150 1160 1170 1180
1180 1190 1200 1210 1220 1230
pF1KA0 EPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPF
1190 1200 1210 1220 1230 1240
1240 1250 1260 1270 1280 1290
pF1KA0 PTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKD
1250 1260 1270 1280 1290 1300
1300 1310 1320 1330 1340 1350
pF1KA0 HSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHGGGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHGGGG
1310 1320 1330 1340 1350 1360
1360 1370 1380 1390 1400 1410
pF1KA0 GGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGP
1370 1380 1390 1400 1410 1420
1420
pF1KA0 PFFAPKRPFFPPRY
::::::::::::::
NP_001 PFFAPKRPFFPPRY
1430
>>XP_016856252 (OMIM: 614695) PREDICTED: regulation of n (1368 aa)
initn: 7023 init1: 6298 opt: 6358 Z-score: 2484.2 bits: 472.1 E(85289): 1.2e-131
Smith-Waterman score: 8707; 93.5% identity (93.5% similar) in 1424 aa overlap (1-1424:38-1368)
10 20 30
pF1KA0 MESIQGLSSWCIENKKHHSTIVYHWMKWLR
::::::::::::::::::::::::::::::
XP_016 GSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KA0 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
:::::::::::::::::: ::::::::::::::::
XP_016 EDRNVYPEEMIVALREAL--------------------------TSTNPKAALKSKIVAE
130 140 150 160
160 170 180 190 200 210
pF1KA0 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
170 180 190 200 210 220
220 230 240 250 260 270
pF1KA0 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
230 240 250 260 270 280
280 290 300 310 320 330
pF1KA0 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
290 300 310 320 330 340
340 350 360 370 380 390
pF1KA0 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
350 360 370 380 390 400
400 410 420 430 440 450
pF1KA0 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTG----------------
410 420 430 440
460 470 480 490 500 510
pF1KA0 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
:::::::::
XP_016 ---------------------------------------------------LSSLLQSVT
450
520 530 540 550 560 570
pF1KA0 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
460 470 480 490 500 510
580 590 600 610 620 630
pF1KA0 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
520 530 540 550 560 570
640 650 660 670 680 690
pF1KA0 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
580 590 600 610 620 630
700 710 720 730 740 750
pF1KA0 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
640 650 660 670 680 690
760 770 780 790 800 810
pF1KA0 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
700 710 720 730 740 750
820 830 840 850 860 870
pF1KA0 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
760 770 780 790 800 810
880 890 900 910 920 930
pF1KA0 SSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPH
820 830 840 850 860 870
940 950 960 970 980 990
pF1KA0 PVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFG
880 890 900 910 920 930
1000 1010 1020 1030 1040 1050
pF1KA0 QAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIET
940 950 960 970 980 990
1060 1070 1080 1090 1100 1110
pF1KA0 LGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASE
1000 1010 1020 1030 1040 1050
1120 1130 1140 1150 1160 1170
pF1KA0 LASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQR
1060 1070 1080 1090 1100 1110
1180 1190 1200 1210 1220 1230
pF1KA0 EPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPF
1120 1130 1140 1150 1160 1170
1240 1250 1260 1270 1280 1290
pF1KA0 PTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKD
1180 1190 1200 1210 1220 1230
1300 1310 1320 1330 1340 1350
pF1KA0 HSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHGGGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHGGGG
1240 1250 1260 1270 1280 1290
1360 1370 1380 1390 1400 1410
pF1KA0 GGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGP
1300 1310 1320 1330 1340 1350
1420
pF1KA0 PFFAPKRPFFPPRY
::::::::::::::
XP_016 PFFAPKRPFFPPRY
1360
>>XP_011507646 (OMIM: 614695) PREDICTED: regulation of n (1394 aa)
initn: 6298 init1: 6298 opt: 6358 Z-score: 2484.0 bits: 472.1 E(85289): 1.3e-131
Smith-Waterman score: 8941; 95.3% identity (95.3% similar) in 1424 aa overlap (1-1424:38-1394)
10 20 30
pF1KA0 MESIQGLSSWCIENKKHHSTIVYHWMKWLR
::::::::::::::::::::::::::::::
XP_011 GSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KA0 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTG----------------
430 440 450 460 470
460 470 480 490 500 510
pF1KA0 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
:::::::::
XP_011 ---------------------------------------------------LSSLLQSVT
480
520 530 540 550 560 570
pF1KA0 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
490 500 510 520 530 540
580 590 600 610 620 630
pF1KA0 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
550 560 570 580 590 600
640 650 660 670 680 690
pF1KA0 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
610 620 630 640 650 660
700 710 720 730 740 750
pF1KA0 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
670 680 690 700 710 720
760 770 780 790 800 810
pF1KA0 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
730 740 750 760 770 780
820 830 840 850 860 870
pF1KA0 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
790 800 810 820 830 840
880 890 900 910 920 930
pF1KA0 SSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPH
850 860 870 880 890 900
940 950 960 970 980 990
pF1KA0 PVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFG
910 920 930 940 950 960
1000 1010 1020 1030 1040 1050
pF1KA0 QAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIET
970 980 990 1000 1010 1020
1060 1070 1080 1090 1100 1110
pF1KA0 LGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASE
1030 1040 1050 1060 1070 1080
1120 1130 1140 1150 1160 1170
pF1KA0 LASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQR
1090 1100 1110 1120 1130 1140
1180 1190 1200 1210 1220 1230
pF1KA0 EPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPF
1150 1160 1170 1180 1190 1200
1240 1250 1260 1270 1280 1290
pF1KA0 PTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKD
1210 1220 1230 1240 1250 1260
1300 1310 1320 1330 1340 1350
pF1KA0 HSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHGGGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHGGGG
1270 1280 1290 1300 1310 1320
1360 1370 1380 1390 1400 1410
pF1KA0 GGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGP
1330 1340 1350 1360 1370 1380
1420
pF1KA0 PFFAPKRPFFPPRY
::::::::::::::
XP_011 PFFAPKRPFFPPRY
1390
>>XP_006711303 (OMIM: 614695) PREDICTED: regulation of n (960 aa)
initn: 5777 init1: 5777 opt: 5779 Z-score: 2262.0 bits: 430.5 E(85289): 2.9e-119
Smith-Waterman score: 5779; 98.0% identity (98.7% similar) in 916 aa overlap (1-916:38-947)
10 20 30
pF1KA0 MESIQGLSSWCIENKKHHSTIVYHWMKWLR
::::::::::::::::::::::::::::::
XP_006 GSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KA0 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA0 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA0 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA0 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA0 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA0 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
730 740 750 760 770 780
760 770 780 790 800 810
pF1KA0 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
790 800 810 820 830 840
820 830 840 850 860 870
pF1KA0 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
850 860 870 880 890 900
880 890 900 910 920 930
pF1KA0 SSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPH
::::::::::::::::::::::::.. : .:.: .. :
XP_006 SSPGLFGAFSVRGNEPGSDRSPSPKH------PCRSHGSPTHVRRGESPGLHHFHHVDD
910 920 930 940 950 960
940 950 960 970 980 990
pF1KA0 PVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFG
>>NP_001284602 (OMIM: 614695) regulation of nuclear pre- (934 aa)
initn: 4878 init1: 4878 opt: 4896 Z-score: 1920.1 bits: 367.2 E(85289): 3.3e-100
Smith-Waterman score: 5545; 95.2% identity (95.9% similar) in 916 aa overlap (1-916:38-921)
10 20 30
pF1KA0 MESIQGLSSWCIENKKHHSTIVYHWMKWLR
::::::::::::::::::::::::::::::
NP_001 GSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KA0 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
:::::::::::::::::: ::::::::::::::::
NP_001 EDRNVYPEEMIVALREAL--------------------------TSTNPKAALKSKIVAE
130 140 150 160
160 170 180 190 200 210
pF1KA0 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
170 180 190 200 210 220
220 230 240 250 260 270
pF1KA0 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
230 240 250 260 270 280
280 290 300 310 320 330
pF1KA0 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
290 300 310 320 330 340
340 350 360 370 380 390
pF1KA0 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
350 360 370 380 390 400
400 410 420 430 440 450
pF1KA0 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
410 420 430 440 450 460
460 470 480 490 500 510
pF1KA0 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
470 480 490 500 510 520
520 530 540 550 560 570
pF1KA0 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
530 540 550 560 570 580
580 590 600 610 620 630
pF1KA0 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
590 600 610 620 630 640
640 650 660 670 680 690
pF1KA0 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
650 660 670 680 690 700
700 710 720 730 740 750
pF1KA0 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
710 720 730 740 750 760
760 770 780 790 800 810
pF1KA0 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
770 780 790 800 810 820
820 830 840 850 860 870
pF1KA0 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
830 840 850 860 870 880
880 890 900 910 920 930
pF1KA0 SSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPH
::::::::::::::::::::::::.. : .:.: .. :
NP_001 SSPGLFGAFSVRGNEPGSDRSPSPKH------PCRSHGSPTHVRRGESPGLHHFHHVDD
890 900 910 920 930
940 950 960 970 980 990
pF1KA0 PVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFG
>>XP_005245090 (OMIM: 614695) PREDICTED: regulation of n (706 aa)
initn: 4087 init1: 4087 opt: 4087 Z-score: 1608.4 bits: 309.1 E(85289): 7.5e-83
Smith-Waterman score: 4087; 99.7% identity (99.8% similar) in 643 aa overlap (1-643:38-680)
10 20 30
pF1KA0 MESIQGLSSWCIENKKHHSTIVYHWMKWLR
::::::::::::::::::::::::::::::
XP_005 GSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KA0 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA0 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA0 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA0 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA0 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
:::::::::: .:
XP_005 LEMKIHNFLKEHPCRSHGSPTHVRRGESPGLHHFHHVDD
670 680 690 700
>>XP_016856255 (OMIM: 614695) PREDICTED: regulation of n (680 aa)
initn: 3910 init1: 3185 opt: 3204 Z-score: 1266.5 bits: 245.8 E(85289): 8.3e-64
Smith-Waterman score: 3853; 95.6% identity (95.8% similar) in 643 aa overlap (1-643:38-654)
10 20 30
pF1KA0 MESIQGLSSWCIENKKHHSTIVYHWMKWLR
::::::::::::::::::::::::::::::
XP_016 GSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KA0 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
:::::::::::::::::: ::::::::::::::::
XP_016 EDRNVYPEEMIVALREAL--------------------------TSTNPKAALKSKIVAE
130 140 150 160
160 170 180 190 200 210
pF1KA0 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
170 180 190 200 210 220
220 230 240 250 260 270
pF1KA0 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
230 240 250 260 270 280
280 290 300 310 320 330
pF1KA0 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
290 300 310 320 330 340
340 350 360 370 380 390
pF1KA0 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
350 360 370 380 390 400
400 410 420 430 440 450
pF1KA0 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
410 420 430 440 450 460
460 470 480 490 500 510
pF1KA0 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
470 480 490 500 510 520
520 530 540 550 560 570
pF1KA0 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
530 540 550 560 570 580
580 590 600 610 620 630
pF1KA0 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
590 600 610 620 630 640
640 650 660 670 680 690
pF1KA0 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
:::::::::: .:
XP_016 LEMKIHNFLKEHPCRSHGSPTHVRRGESPGLHHFHHVDD
650 660 670 680
>>XP_016856254 (OMIM: 614695) PREDICTED: regulation of n (893 aa)
initn: 2919 init1: 2837 opt: 2882 Z-score: 1140.1 bits: 222.8 E(85289): 9.1e-57
Smith-Waterman score: 5217; 90.7% identity (91.4% similar) in 916 aa overlap (1-916:38-880)
10 20 30
pF1KA0 MESIQGLSSWCIENKKHHSTIVYHWMKWLR
::::::::::::::::::::::::::::::
XP_016 GSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KA0 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTG----------------
430 440 450 460 470
460 470 480 490 500 510
pF1KA0 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
:::::::::
XP_016 ---------------------------------------------------LSSLLQSVT
480
520 530 540 550 560 570
pF1KA0 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
490 500 510 520 530 540
580 590 600 610 620 630
pF1KA0 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
550 560 570 580 590 600
640 650 660 670 680 690
pF1KA0 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
610 620 630 640 650 660
700 710 720 730 740 750
pF1KA0 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
670 680 690 700 710 720
760 770 780 790 800 810
pF1KA0 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
730 740 750 760 770 780
820 830 840 850 860 870
pF1KA0 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
790 800 810 820 830 840
880 890 900 910 920 930
pF1KA0 SSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPH
::::::::::::::::::::::::.. : .:.: .. :
XP_016 SSPGLFGAFSVRGNEPGSDRSPSPKH------PCRSHGSPTHVRRGESPGLHHFHHVDD
850 860 870 880 890
940 950 960 970 980 990
pF1KA0 PVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFG
1424 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 02:38:10 2016 done: Sat Nov 5 02:38:13 2016
Total Scan time: 18.960 Total Display time: 0.450
Function used was FASTA [36.3.4 Apr, 2011]