Result of FASTA (omim) for
pF1KA0160
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0160, 739 aa
1>>>pF1KA0160 739 - 739 aa - 739 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3690+/-0.000434; mu= 12.6095+/- 0.027
mean_var=219.0272+/-45.665, 0's: 0 Z-trim(117.7): 52 B-trim: 776 in 1/56
Lambda= 0.086661
statistics sampled from 29871 (29934) to 29871 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.687), E-opt: 0.2 (0.351), width: 16
Scan time: 12.640
The best scores are: opt bits E(85289)
NP_056170 (OMIM: 606245) polycomb protein SUZ12 is ( 739) 4943 631.7 3.1e-180
XP_006721857 (OMIM: 606245) PREDICTED: polycomb pr ( 603) 4043 519.1 2e-146
NP_001308136 (OMIM: 606245) polycomb protein SUZ12 ( 716) 3987 512.2 2.9e-144
XP_016879898 (OMIM: 606245) PREDICTED: polycomb pr ( 441) 2969 384.7 4.4e-106
>>NP_056170 (OMIM: 606245) polycomb protein SUZ12 isofor (739 aa)
initn: 4943 init1: 4943 opt: 4943 Z-score: 3356.7 bits: 631.7 E(85289): 3.1e-180
Smith-Waterman score: 4943; 100.0% identity (100.0% similar) in 739 aa overlap (1-739:1-739)
10 20 30 40 50 60
pF1KA0 MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 AAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 RNSRTNIKRKTFKVDDMLSKVEKMKGEQESHSLSAHLQLTFTGFFHKNDKPSPNSENEQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RNSRTNIKRKTFKVDDMLSKVEKMKGEQESHSLSAHLQLTFTGFFHKNDKPSPNSENEQN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 NSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRNREDGEKTFVAQMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRNREDGEKTFVAQMT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 VFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 WTGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVKESLTTDLQTRKEKDTPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 WTGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVKESLTTDLQTRKEKDTPN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 ENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 HPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 EEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 VSMHDFNLISIMSIDKAVTKLREMQQKLEKGESASPANEEITEEQNGTANGFSEINSKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VSMHDFNLISIMSIDKAVTKLREMQQKLEKGESASPANEEITEEQNGTANGFSEINSKEK
670 680 690 700 710 720
730
pF1KA0 ALETDSVSGVSKQSKKQKL
:::::::::::::::::::
NP_056 ALETDSVSGVSKQSKKQKL
730
>>XP_006721857 (OMIM: 606245) PREDICTED: polycomb protei (603 aa)
initn: 4043 init1: 4043 opt: 4043 Z-score: 2749.6 bits: 519.1 E(85289): 2e-146
Smith-Waterman score: 4043; 100.0% identity (100.0% similar) in 603 aa overlap (137-739:1-603)
110 120 130 140 150 160
pF1KA0 APIFLHRTLTYMSHRNSRTNIKRKTFKVDDMLSKVEKMKGEQESHSLSAHLQLTFTGFFH
::::::::::::::::::::::::::::::
XP_006 MLSKVEKMKGEQESHSLSAHLQLTFTGFFH
10 20 30
170 180 190 200 210 220
pF1KA0 KNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGN
40 50 60 70 80 90
230 240 250 260 270 280
pF1KA0 FPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKR
100 110 120 130 140 150
290 300 310 320 330 340
pF1KA0 NREDGEKTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NREDGEKTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPF
160 170 180 190 200 210
350 360 370 380 390 400
pF1KA0 ETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVKESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVKESL
220 230 240 250 260 270
410 420 430 440 450 460
pF1KA0 TTDLQTRKEKDTPNENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TTDLQTRKEKDTPNENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKH
280 290 300 310 320 330
470 480 490 500 510 520
pF1KA0 LKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPIT
340 350 360 370 380 390
530 540 550 560 570 580
pF1KA0 HILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDE
400 410 420 430 440 450
590 600 610 620 630 640
pF1KA0 KDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQK
460 470 480 490 500 510
650 660 670 680 690 700
pF1KA0 IIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVTKLREMQQKLEKGESASPANEEITEEQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVTKLREMQQKLEKGESASPANEEITEEQN
520 530 540 550 560 570
710 720 730
pF1KA0 GTANGFSEINSKEKALETDSVSGVSKQSKKQKL
:::::::::::::::::::::::::::::::::
XP_006 GTANGFSEINSKEKALETDSVSGVSKQSKKQKL
580 590 600
>>NP_001308136 (OMIM: 606245) polycomb protein SUZ12 iso (716 aa)
initn: 4781 init1: 3948 opt: 3987 Z-score: 2710.9 bits: 512.2 E(85289): 2.9e-144
Smith-Waterman score: 4739; 96.9% identity (96.9% similar) in 739 aa overlap (1-739:1-716)
10 20 30 40 50 60
pF1KA0 MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 AAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 RNSRTNIKRKTFKVDDMLSKVEKMKGEQESHSLSAHLQLTFTGFFHKNDKPSPNSENEQN
:::::::: :::::::::::::::::::::::::::::
NP_001 RNSRTNIK-----------------------SLSAHLQLTFTGFFHKNDKPSPNSENEQN
130 140 150
190 200 210 220 230 240
pF1KA0 SVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPS
160 170 180 190 200 210
250 260 270 280 290 300
pF1KA0 NSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRNREDGEKTFVAQMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRNREDGEKTFVAQMT
220 230 240 250 260 270
310 320 330 340 350 360
pF1KA0 VFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLR
280 290 300 310 320 330
370 380 390 400 410 420
pF1KA0 WTGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVKESLTTDLQTRKEKDTPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WTGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVKESLTTDLQTRKEKDTPN
340 350 360 370 380 390
430 440 450 460 470 480
pF1KA0 ENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVY
400 410 420 430 440 450
490 500 510 520 530 540
pF1KA0 HPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASM
460 470 480 490 500 510
550 560 570 580 590 600
pF1KA0 SEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQI
520 530 540 550 560 570
610 620 630 640 650 660
pF1KA0 EEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHL
580 590 600 610 620 630
670 680 690 700 710 720
pF1KA0 VSMHDFNLISIMSIDKAVTKLREMQQKLEKGESASPANEEITEEQNGTANGFSEINSKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSMHDFNLISIMSIDKAVTKLREMQQKLEKGESASPANEEITEEQNGTANGFSEINSKEK
640 650 660 670 680 690
730
pF1KA0 ALETDSVSGVSKQSKKQKL
:::::::::::::::::::
NP_001 ALETDSVSGVSKQSKKQKL
700 710
>>XP_016879898 (OMIM: 606245) PREDICTED: polycomb protei (441 aa)
initn: 2969 init1: 2969 opt: 2969 Z-score: 2025.5 bits: 384.7 E(85289): 4.4e-106
Smith-Waterman score: 2969; 100.0% identity (100.0% similar) in 441 aa overlap (299-739:1-441)
270 280 290 300 310 320
pF1KA0 ETNENIDVNEELPARRKRNREDGEKTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPIS
::::::::::::::::::::::::::::::
XP_016 MTVFDKNRRLQLLDGEYEVAMQEMEECPIS
10 20 30
330 340 350 360 370 380
pF1KA0 KKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATRNSESLHQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATRNSESLHQE
40 50 60 70 80 90
390 400 410 420 430 440
pF1KA0 NKPGSVKPTQTIAVKESLTTDLQTRKEKDTPNENRQKLRIFYQFLYNNNTRQQTEARDDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKPGSVKPTQTIAVKESLTTDLQTRKEKDTPNENRQKLRIFYQFLYNNNTRQQTEARDDL
100 110 120 130 140 150
450 460 470 480 490 500
pF1KA0 HCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHR
160 170 180 190 200 210
510 520 530 540 550 560
pF1KA0 QPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHS
220 230 240 250 260 270
570 580 590 600 610 620
pF1KA0 DTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIA
280 290 300 310 320 330
630 640 650 660 670 680
pF1KA0 DNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVTKLREMQQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVTKLREMQQKL
340 350 360 370 380 390
690 700 710 720 730
pF1KA0 EKGESASPANEEITEEQNGTANGFSEINSKEKALETDSVSGVSKQSKKQKL
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKGESASPANEEITEEQNGTANGFSEINSKEKALETDSVSGVSKQSKKQKL
400 410 420 430 440
739 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 19:29:10 2016 done: Thu Nov 3 19:29:12 2016
Total Scan time: 12.640 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]