Result of FASTA (omim) for
pF1KA0136
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0136, 939 aa
1>>>pF1KA0136 939 - 939 aa - 939 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.6263+/-0.000568; mu= -0.3425+/- 0.035
mean_var=236.0679+/-49.582, 0's: 0 Z-trim(112.9): 59 B-trim: 874 in 2/52
Lambda= 0.083475
statistics sampled from 21929 (21965) to 21929 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.604), E-opt: 0.2 (0.258), width: 16
Scan time: 10.370
The best scores are: opt bits E(85289)
NP_056173 (OMIM: 610078) MORC family CW-type zinc ( 939) 6201 761.4 0
XP_016883800 (OMIM: 610078) PREDICTED: MORC family ( 868) 5705 701.7 4.2e-201
XP_011527820 (OMIM: 610078) PREDICTED: MORC family ( 868) 5705 701.7 4.2e-201
NP_001307374 (OMIM: 610078) MORC family CW-type zi ( 868) 5705 701.7 4.2e-201
NP_001307375 (OMIM: 610078) MORC family CW-type zi ( 868) 5705 701.7 4.2e-201
XP_016883801 (OMIM: 610078) PREDICTED: MORC family ( 555) 3655 454.7 6e-127
NP_001078823 (OMIM: 300970) MORC family CW-type zi ( 900) 1795 230.8 2.4e-59
NP_078933 (OMIM: 300970) MORC family CW-type zinc ( 937) 1795 230.8 2.5e-59
XP_016885333 (OMIM: 300970) PREDICTED: MORC family ( 808) 1527 198.5 1.1e-49
XP_005262247 (OMIM: 300970) PREDICTED: MORC family ( 845) 1527 198.5 1.2e-49
XP_011529329 (OMIM: 300970) PREDICTED: MORC family ( 760) 1148 152.8 6e-36
XP_006724754 (OMIM: 300970) PREDICTED: MORC family ( 815) 989 133.7 3.7e-30
NP_055244 (OMIM: 603205) MORC family CW-type zinc ( 984) 440 67.6 3.4e-10
XP_005247419 (OMIM: 603205) PREDICTED: MORC family (1014) 440 67.7 3.5e-10
XP_011510995 (OMIM: 603205) PREDICTED: MORC family ( 951) 437 67.3 4.3e-10
XP_016861658 (OMIM: 603205) PREDICTED: MORC family ( 981) 437 67.3 4.4e-10
XP_011510994 (OMIM: 603205) PREDICTED: MORC family ( 986) 437 67.3 4.4e-10
XP_011510993 (OMIM: 603205) PREDICTED: MORC family (1016) 437 67.3 4.5e-10
NP_001290186 (OMIM: 616661,616688) MORC family CW- (1029) 422 65.5 1.6e-09
NP_001290185 (OMIM: 616661,616688) MORC family CW- (1032) 422 65.5 1.6e-09
XP_016884156 (OMIM: 616661,616688) PREDICTED: MORC (1034) 409 63.9 4.7e-09
XP_011528306 (OMIM: 616661,616688) PREDICTED: MORC (1037) 409 63.9 4.7e-09
XP_016884157 (OMIM: 616661,616688) PREDICTED: MORC ( 970) 318 53.0 8.9e-06
NP_055756 (OMIM: 616661,616688) MORC family CW-typ ( 970) 318 53.0 8.9e-06
XP_011510996 (OMIM: 603205) PREDICTED: MORC family ( 917) 240 43.5 0.0057
>>NP_056173 (OMIM: 610078) MORC family CW-type zinc fing (939 aa)
initn: 6201 init1: 6201 opt: 6201 Z-score: 4053.8 bits: 761.4 E(85289): 0
Smith-Waterman score: 6201; 100.0% identity (100.0% similar) in 939 aa overlap (1-939:1-939)
10 20 30 40 50 60
pF1KA0 MAAQPPRGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVINDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MAAQPPRGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVINDH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ICLTFTDNGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGLYGNGFKSGSMRLGKDAIVFTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ICLTFTDNGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGLYGNGFKSGSMRLGKDAIVFTK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 NGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKHRQMINLAESKASLAAILEHSLFSTEQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKHRQMINLAESKASLAAILEHSLFSTEQK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LLAELDAIIGKKGTRIIIWNLRSYKNATEFDFEKDKYDIRIPEDLDEITGKKGYKKQERM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LLAELDAIIGKKGTRIIIWNLRSYKNATEFDFEKDKYDIRIPEDLDEITGKKGYKKQERM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 DQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAYIERDVYRPKFLSKTVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAYIERDVYRPKFLSKTVR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 ITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGVGVVGIIECNFLKPTHNKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGVGVVGIIECNFLKPTHNKQD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 FDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLPVEDIQKRPDQTWVQCDACLKWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLPVEDIQKRPDQTWVQCDACLKWR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 KLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTNKEKFRIRQPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTNKEKFRIRQPE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 MIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYATRLLNNHQVPPQSEPESNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYATRLLNNHQVPPQSEPESNS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 LKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILEENSTPKPAVDHDIDMKSEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILEENSTPKPAVDHDIDMKSEQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 SHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEETVEDEID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEETVEDEID
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 VRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 TDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 ERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLRSLRVNVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLRSLRVNVG
850 860 870 880 890 900
910 920 930
pF1KA0 QLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST
:::::::::::::::::::::::::::::::::::::::
NP_056 QLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST
910 920 930
>>XP_016883800 (OMIM: 610078) PREDICTED: MORC family CW- (868 aa)
initn: 5705 init1: 5705 opt: 5705 Z-score: 3731.5 bits: 701.7 E(85289): 4.2e-201
Smith-Waterman score: 5705; 100.0% identity (100.0% similar) in 868 aa overlap (72-939:1-868)
50 60 70 80 90 100
pF1KA0 DPDVNAKQIWIDKTVINDHICLTFTDNGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGLYG
::::::::::::::::::::::::::::::
XP_016 MTSDKLHKMLSFGFSDKVTMNGHVPVGLYG
10 20 30
110 120 130 140 150 160
pF1KA0 NGFKSGSMRLGKDAIVFTKNGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKHRQMINLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGFKSGSMRLGKDAIVFTKNGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKHRQMINLAE
40 50 60 70 80 90
170 180 190 200 210 220
pF1KA0 SKASLAAILEHSLFSTEQKLLAELDAIIGKKGTRIIIWNLRSYKNATEFDFEKDKYDIRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKASLAAILEHSLFSTEQKLLAELDAIIGKKGTRIIIWNLRSYKNATEFDFEKDKYDIRI
100 110 120 130 140 150
230 240 250 260 270 280
pF1KA0 PEDLDEITGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEDLDEITGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKS
160 170 180 190 200 210
290 300 310 320 330 340
pF1KA0 LAYIERDVYRPKFLSKTVRITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAYIERDVYRPKFLSKTVRITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGV
220 230 240 250 260 270
350 360 370 380 390 400
pF1KA0 GVVGIIECNFLKPTHNKQDFDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLPVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVVGIIECNFLKPTHNKQDFDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLPVED
280 290 300 310 320 330
410 420 430 440 450 460
pF1KA0 IQKRPDQTWVQCDACLKWRKLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQKRPDQTWVQCDACLKWRKLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPT
340 350 360 370 380 390
470 480 490 500 510 520
pF1KA0 YEKTYKKTNKEKFRIRQPEMIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEKTYKKTNKEKFRIRQPEMIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYA
400 410 420 430 440 450
530 540 550 560 570 580
pF1KA0 TRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILE
460 470 480 490 500 510
590 600 610 620 630 640
pF1KA0 ENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQ
520 530 540 550 560 570
650 660 670 680 690 700
pF1KA0 TEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRN
580 590 600 610 620 630
710 720 730 740 750 760
pF1KA0 QLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESING
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESING
640 650 660 670 680 690
770 780 790 800 810 820
pF1KA0 KSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFR
700 710 720 730 740 750
830 840 850 860 870 880
pF1KA0 QLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEES
760 770 780 790 800 810
890 900 910 920 930
pF1KA0 VNHMDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNHMDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST
820 830 840 850 860
>>XP_011527820 (OMIM: 610078) PREDICTED: MORC family CW- (868 aa)
initn: 5705 init1: 5705 opt: 5705 Z-score: 3731.5 bits: 701.7 E(85289): 4.2e-201
Smith-Waterman score: 5705; 100.0% identity (100.0% similar) in 868 aa overlap (72-939:1-868)
50 60 70 80 90 100
pF1KA0 DPDVNAKQIWIDKTVINDHICLTFTDNGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGLYG
::::::::::::::::::::::::::::::
XP_011 MTSDKLHKMLSFGFSDKVTMNGHVPVGLYG
10 20 30
110 120 130 140 150 160
pF1KA0 NGFKSGSMRLGKDAIVFTKNGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKHRQMINLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGFKSGSMRLGKDAIVFTKNGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKHRQMINLAE
40 50 60 70 80 90
170 180 190 200 210 220
pF1KA0 SKASLAAILEHSLFSTEQKLLAELDAIIGKKGTRIIIWNLRSYKNATEFDFEKDKYDIRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKASLAAILEHSLFSTEQKLLAELDAIIGKKGTRIIIWNLRSYKNATEFDFEKDKYDIRI
100 110 120 130 140 150
230 240 250 260 270 280
pF1KA0 PEDLDEITGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEDLDEITGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKS
160 170 180 190 200 210
290 300 310 320 330 340
pF1KA0 LAYIERDVYRPKFLSKTVRITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAYIERDVYRPKFLSKTVRITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGV
220 230 240 250 260 270
350 360 370 380 390 400
pF1KA0 GVVGIIECNFLKPTHNKQDFDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLPVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVVGIIECNFLKPTHNKQDFDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLPVED
280 290 300 310 320 330
410 420 430 440 450 460
pF1KA0 IQKRPDQTWVQCDACLKWRKLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQKRPDQTWVQCDACLKWRKLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPT
340 350 360 370 380 390
470 480 490 500 510 520
pF1KA0 YEKTYKKTNKEKFRIRQPEMIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEKTYKKTNKEKFRIRQPEMIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYA
400 410 420 430 440 450
530 540 550 560 570 580
pF1KA0 TRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILE
460 470 480 490 500 510
590 600 610 620 630 640
pF1KA0 ENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQ
520 530 540 550 560 570
650 660 670 680 690 700
pF1KA0 TEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRN
580 590 600 610 620 630
710 720 730 740 750 760
pF1KA0 QLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESING
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESING
640 650 660 670 680 690
770 780 790 800 810 820
pF1KA0 KSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFR
700 710 720 730 740 750
830 840 850 860 870 880
pF1KA0 QLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEES
760 770 780 790 800 810
890 900 910 920 930
pF1KA0 VNHMDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNHMDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST
820 830 840 850 860
>>NP_001307374 (OMIM: 610078) MORC family CW-type zinc f (868 aa)
initn: 5705 init1: 5705 opt: 5705 Z-score: 3731.5 bits: 701.7 E(85289): 4.2e-201
Smith-Waterman score: 5705; 100.0% identity (100.0% similar) in 868 aa overlap (72-939:1-868)
50 60 70 80 90 100
pF1KA0 DPDVNAKQIWIDKTVINDHICLTFTDNGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGLYG
::::::::::::::::::::::::::::::
NP_001 MTSDKLHKMLSFGFSDKVTMNGHVPVGLYG
10 20 30
110 120 130 140 150 160
pF1KA0 NGFKSGSMRLGKDAIVFTKNGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKHRQMINLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGFKSGSMRLGKDAIVFTKNGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKHRQMINLAE
40 50 60 70 80 90
170 180 190 200 210 220
pF1KA0 SKASLAAILEHSLFSTEQKLLAELDAIIGKKGTRIIIWNLRSYKNATEFDFEKDKYDIRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKASLAAILEHSLFSTEQKLLAELDAIIGKKGTRIIIWNLRSYKNATEFDFEKDKYDIRI
100 110 120 130 140 150
230 240 250 260 270 280
pF1KA0 PEDLDEITGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEDLDEITGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKS
160 170 180 190 200 210
290 300 310 320 330 340
pF1KA0 LAYIERDVYRPKFLSKTVRITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAYIERDVYRPKFLSKTVRITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGV
220 230 240 250 260 270
350 360 370 380 390 400
pF1KA0 GVVGIIECNFLKPTHNKQDFDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLPVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVVGIIECNFLKPTHNKQDFDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLPVED
280 290 300 310 320 330
410 420 430 440 450 460
pF1KA0 IQKRPDQTWVQCDACLKWRKLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQKRPDQTWVQCDACLKWRKLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPT
340 350 360 370 380 390
470 480 490 500 510 520
pF1KA0 YEKTYKKTNKEKFRIRQPEMIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEKTYKKTNKEKFRIRQPEMIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYA
400 410 420 430 440 450
530 540 550 560 570 580
pF1KA0 TRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILE
460 470 480 490 500 510
590 600 610 620 630 640
pF1KA0 ENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQ
520 530 540 550 560 570
650 660 670 680 690 700
pF1KA0 TEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRN
580 590 600 610 620 630
710 720 730 740 750 760
pF1KA0 QLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESING
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESING
640 650 660 670 680 690
770 780 790 800 810 820
pF1KA0 KSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFR
700 710 720 730 740 750
830 840 850 860 870 880
pF1KA0 QLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEES
760 770 780 790 800 810
890 900 910 920 930
pF1KA0 VNHMDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNHMDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST
820 830 840 850 860
>>NP_001307375 (OMIM: 610078) MORC family CW-type zinc f (868 aa)
initn: 5705 init1: 5705 opt: 5705 Z-score: 3731.5 bits: 701.7 E(85289): 4.2e-201
Smith-Waterman score: 5705; 100.0% identity (100.0% similar) in 868 aa overlap (72-939:1-868)
50 60 70 80 90 100
pF1KA0 DPDVNAKQIWIDKTVINDHICLTFTDNGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGLYG
::::::::::::::::::::::::::::::
NP_001 MTSDKLHKMLSFGFSDKVTMNGHVPVGLYG
10 20 30
110 120 130 140 150 160
pF1KA0 NGFKSGSMRLGKDAIVFTKNGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKHRQMINLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGFKSGSMRLGKDAIVFTKNGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKHRQMINLAE
40 50 60 70 80 90
170 180 190 200 210 220
pF1KA0 SKASLAAILEHSLFSTEQKLLAELDAIIGKKGTRIIIWNLRSYKNATEFDFEKDKYDIRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKASLAAILEHSLFSTEQKLLAELDAIIGKKGTRIIIWNLRSYKNATEFDFEKDKYDIRI
100 110 120 130 140 150
230 240 250 260 270 280
pF1KA0 PEDLDEITGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEDLDEITGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKS
160 170 180 190 200 210
290 300 310 320 330 340
pF1KA0 LAYIERDVYRPKFLSKTVRITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAYIERDVYRPKFLSKTVRITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGV
220 230 240 250 260 270
350 360 370 380 390 400
pF1KA0 GVVGIIECNFLKPTHNKQDFDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLPVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVVGIIECNFLKPTHNKQDFDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLPVED
280 290 300 310 320 330
410 420 430 440 450 460
pF1KA0 IQKRPDQTWVQCDACLKWRKLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQKRPDQTWVQCDACLKWRKLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPT
340 350 360 370 380 390
470 480 490 500 510 520
pF1KA0 YEKTYKKTNKEKFRIRQPEMIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEKTYKKTNKEKFRIRQPEMIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYA
400 410 420 430 440 450
530 540 550 560 570 580
pF1KA0 TRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILE
460 470 480 490 500 510
590 600 610 620 630 640
pF1KA0 ENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQ
520 530 540 550 560 570
650 660 670 680 690 700
pF1KA0 TEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRN
580 590 600 610 620 630
710 720 730 740 750 760
pF1KA0 QLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESING
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESING
640 650 660 670 680 690
770 780 790 800 810 820
pF1KA0 KSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFR
700 710 720 730 740 750
830 840 850 860 870 880
pF1KA0 QLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEES
760 770 780 790 800 810
890 900 910 920 930
pF1KA0 VNHMDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNHMDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST
820 830 840 850 860
>>XP_016883801 (OMIM: 610078) PREDICTED: MORC family CW- (555 aa)
initn: 3655 init1: 3655 opt: 3655 Z-score: 2400.1 bits: 454.7 E(85289): 6e-127
Smith-Waterman score: 3655; 100.0% identity (100.0% similar) in 555 aa overlap (385-939:1-555)
360 370 380 390 400 410
pF1KA0 THNKQDFDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLPVEDIQKRPDQTWVQCD
::::::::::::::::::::::::::::::
XP_016 MKVKKNTEYPLNLPVEDIQKRPDQTWVQCD
10 20 30
420 430 440 450 460 470
pF1KA0 ACLKWRKLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTNKEKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACLKWRKLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTNKEKF
40 50 60 70 80 90
480 490 500 510 520 530
pF1KA0 RIRQPEMIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYATRLLNNHQVPPQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIRQPEMIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYATRLLNNHQVPPQS
100 110 120 130 140 150
540 550 560 570 580 590
pF1KA0 EPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILEENSTPKPAVDHDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILEENSTPKPAVDHDI
160 170 180 190 200 210
600 610 620 630 640 650
pF1KA0 DMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEET
220 230 240 250 260 270
660 670 680 690 700 710
pF1KA0 VEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYK
280 290 300 310 320 330
720 730 740 750 760 770
pF1KA0 RQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQ
340 350 360 370 380 390
780 790 800 810 820 830
pF1KA0 QALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYK
400 410 420 430 440 450
840 850 860 870 880 890
pF1KA0 SEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLRS
460 470 480 490 500 510
900 910 920 930
pF1KA0 LRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST
520 530 540 550
>>NP_001078823 (OMIM: 300970) MORC family CW-type zinc f (900 aa)
initn: 1384 init1: 662 opt: 1795 Z-score: 1186.5 bits: 230.8 E(85289): 2.4e-59
Smith-Waterman score: 1815; 37.9% identity (64.7% similar) in 897 aa overlap (8-887:29-875)
10 20 30
pF1KA0 MAAQPPRGIRLSALCPKFLHTNSTSHTWPFSAVAELIDN
:::::.. :..:..::.::: ::::.:::.::
NP_001 MLLYRGAPAGPGAPGCGLARPGGGPQAFGIRLSTMSPRYLQSNSSSHTRPFSAIAELLDN
10 20 30 40 50 60
40 50 60 70 80 90
pF1KA0 AYDPDVNAKQIWIDKTVINDHICLTFTDNGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGL
: ::::.:. ..:: .... ::::::.: ::: :::.::::::.::: ... :.:.
NP_001 AVDPDVSARTVFIDVEEVKNKSCLTFTDDGCGMTPHKLHRMLSFGFTDKVIKKSQCPIGV
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 YGNGFKSGSMRLGKDAIVFTKNGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKH-RQMIN
.:::::::::::::::.:::::: ...:::::::::: ..:. :.:::: ::.. ..::
NP_001 FGNGFKSGSMRLGKDALVFTKNGGTLTVGLLSQTYLECVQAQAVIVPIVPFNQQNKKMII
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 LAESKASLAAILEHSLFSTEQKLLAELDAIIGKKGTRIIIWNLRSYKNA-TEFDFEKDKY
.: :: :::..:.:. :. :::..::: ::::::..:::.: ::. .:.::. :.:
NP_001 TEDSLPSLEAILNYSIFNRENDLLAQFDAIPGKKGTRVLIWNIRRNKNGKSELDFDTDQY
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 DIRIPEDLDEITGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQL
:: . :.: : .: ::..:::::.:.:::.::::.:.:: .:: ::.
NP_001 DILVS-DFDTEEKMTGGVTSE-----LPETEYSLRAFCGILYMKPRMKIFLRQKKVTTQM
250 260 270 280 290
280 290 300 310 320 330
pF1KA0 VSKSLAYIERDVYRPKFLSKTVRITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRAN
..:::: .: :.:.: : .: :::::::.:.:....:::::: :::::..::::::.. .
NP_001 IAKSLANVEYDTYKPTFTNKQVRITFGFSCKNSNQFGIMMYHNNRLIKSFEKVGCQVKPT
300 310 320 330 340 350
340 350 360 370 380 390
pF1KA0 -NMGVGVVGIIECNFLKPTHNKQDFDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLN
. ::::.:.::::::::..:::::.::.::::::.::..::: ::.: . : : .
NP_001 RGEGVGVIGVIECNFLKPAYNKQDFEYTKEYRLTINALAQKLNAYWKEKTSQDNFE--TS
360 370 380 390 400 410
400 410 420 430 440 450
pF1KA0 LPVEDIQKRPDQTWVQCDACLKWRKLPDGMD--QLPEKWYCSNNPDPQFRNCEVPEEPE-
.. : : ::::::::: :::::::: .: .:: .:.: : :..: : :::: :
NP_001 TVARPIPKVPDQTWVQCDECLKWRKLPGKIDPSMLPARWFCYYNSHPKYRRCSVPEEQEL
420 430 440 450 460 470
460 470 480 490 500 510
pF1KA0 -DEDLVHPTYEKTYKKTNKEKFRIRQPEMIPRINAELLFRPTALSTPSFSSPKESVPRRH
:::: .:..:.. ... . .: : . ::.: . . ..
NP_001 TDEDLC-------LSKAKKQEQTVEEKKKMPMENE---------NHQVFSNPPKILTVQE
480 490 500 510
520 530 540 550 560 570
pF1KA0 LSEGTNSYATRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDD
.. : :. . . :. :. : .. .: : . . :... ..::... . :..
NP_001 MA-GLNNKTIGYEGIHS--PSVLPSGGEESRSPSLQLKPLDSSVLQFSSKYKWIL--GEE
520 530 540 550 560 570
580 590 600 610 620 630
pF1KA0 DDEDVIILEENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRC
: :. : :..:. .: . .:: . : . : :... ..:: :
NP_001 PVEKRRRLQ-NEMTTPSLDY--SMPAPYRRVE---APVAY-----PEGENSHDKSSSERS
580 590 600 610 620
640 650 660 670 680
pF1KA0 DQGNTAATQTEVPSLVVKKEET---VEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSA
:. . . ...:. : :. . .:: .: . ..:.. :.
NP_001 TPPYLFPEYPEASKNTGQNREVSILYPGAKDQRQGS-LLPEELEDQMPRLVAEESNRGST
630 640 650 660 670
690 700 710 720 730 740
pF1KA0 DDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTE
. .:. . .... . :. . : .... : . . :.
NP_001 T---INKEEVNKGPFVAVVGVAKGVRDSGAPIQLIPFNREELAERRKAVESWNPVPYSVA
680 690 700 710 720 730
750 760 770 780 790 800
pF1KA0 TDAV---FLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESK
. :. . :. : :: : . . .. .:.:.::. :..: :: : .
NP_001 SAAIPAAAIGEKARGYEESEGHNTPKLKNQ-RELEELKRTTEKLERVLAE-----RNLFQ
740 750 760 770 780 790
810 820 830 840 850 860
pF1KA0 SEMDEMAVQLDDVFRQLDKCSIERDQYKS-EVELLEMEKSQI---RSQCEELKTEVEQLK
....:. . . .. : . : :.. :.: : :... ... . ::.:.:. :
NP_001 QKVEELEQERNHWQSEFKKVQHELVIYSTQEAEGLYWSKKHMGYRQAEFQILKAELERTK
800 810 820 830 840 850
870 880 890 900 910 920
pF1KA0 STNQQTATDVSTSSNIEESVNHMDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVV
.:. .. . . : ... .:
NP_001 EEKQELKEKLKETETHLEMLQKAQGFGKAYAATYPRQLSPYFCPPSLGAS
860 870 880 890 900
>>NP_078933 (OMIM: 300970) MORC family CW-type zinc fing (937 aa)
initn: 1482 init1: 662 opt: 1795 Z-score: 1186.2 bits: 230.8 E(85289): 2.5e-59
Smith-Waterman score: 1910; 38.0% identity (64.8% similar) in 948 aa overlap (8-931:29-931)
10 20 30
pF1KA0 MAAQPPRGIRLSALCPKFLHTNSTSHTWPFSAVAELIDN
:::::.. :..:..::.::: ::::.:::.::
NP_078 MLLYRGAPAGPGAPGCGLARPGGGPQAFGIRLSTMSPRYLQSNSSSHTRPFSAIAELLDN
10 20 30 40 50 60
40 50 60 70 80 90
pF1KA0 AYDPDVNAKQIWIDKTVINDHICLTFTDNGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGL
: ::::.:. ..:: .... ::::::.: ::: :::.::::::.::: ... :.:.
NP_078 AVDPDVSARTVFIDVEEVKNKSCLTFTDDGCGMTPHKLHRMLSFGFTDKVIKKSQCPIGV
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 YGNGFKSGSMRLGKDAIVFTKNGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKH-RQMIN
.:::::::::::::::.:::::: ...:::::::::: ..:. :.:::: ::.. ..::
NP_078 FGNGFKSGSMRLGKDALVFTKNGGTLTVGLLSQTYLECVQAQAVIVPIVPFNQQNKKMII
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 LAESKASLAAILEHSLFSTEQKLLAELDAIIGKKGTRIIIWNLRSYKNA-TEFDFEKDKY
.: :: :::..:.:. :. :::..::: ::::::..:::.: ::. .:.::. :.:
NP_078 TEDSLPSLEAILNYSIFNRENDLLAQFDAIPGKKGTRVLIWNIRRNKNGKSELDFDTDQY
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 DIRIPEDLDEITGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQL
:: . :.: : .: ::..:::::.:.:::.::::.:.:: .:: ::.
NP_078 DILVS-DFDTEEKMTGGVTSE-----LPETEYSLRAFCGILYMKPRMKIFLRQKKVTTQM
250 260 270 280 290
280 290 300 310 320 330
pF1KA0 VSKSLAYIERDVYRPKFLSKTVRITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRAN
..:::: .: :.:.: : .: :::::::.:.:....:::::: :::::..::::::.. .
NP_078 IAKSLANVEYDTYKPTFTNKQVRITFGFSCKNSNQFGIMMYHNNRLIKSFEKVGCQVKPT
300 310 320 330 340 350
340 350 360 370 380 390
pF1KA0 -NMGVGVVGIIECNFLKPTHNKQDFDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLN
. ::::.:.::::::::..:::::.::.::::::.::..::: ::.: . : : .
NP_078 RGEGVGVIGVIECNFLKPAYNKQDFEYTKEYRLTINALAQKLNAYWKEKTSQDNFE--TS
360 370 380 390 400 410
400 410 420 430 440 450
pF1KA0 LPVEDIQKRPDQTWVQCDACLKWRKLPDGMD--QLPEKWYCSNNPDPQFRNCEVPEEPE-
.. : : ::::::::: :::::::: .: .:: .:.: : :..: : :::: :
NP_078 TVARPIPKVPDQTWVQCDECLKWRKLPGKIDPSMLPARWFCYYNSHPKYRRCSVPEEQEL
420 430 440 450 460 470
460 470 480 490 500 510
pF1KA0 -DEDLVHPTYEKTYKKTNKEKFRIRQPEMIPRINAELLFRPTALSTPSFSSPKESVPRRH
:::: .:..:.. ... . .: : . ::.: . . ..
NP_078 TDEDLC-------LSKAKKQEQTVEEKKKMPMENE---------NHQVFSNPPKILTVQE
480 490 500 510
520 530 540 550 560 570
pF1KA0 LSEGTNSYATRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDD
.. : :. . . :. :. : .. .: : . . :... ..::... . :..
NP_078 MA-GLNNKTIGYEGIHS--PSVLPSGGEESRSPSLQLKPLDSSVLQFSSKYKWIL--GEE
520 530 540 550 560 570
580 590 600 610 620 630
pF1KA0 DDEDVIILEENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRC
: :. : :..:. .: . .:: . : . : :... ..:: :
NP_078 PVEKRRRLQ-NEMTTPSLDY--SMPAPYRRVE---APVAY-----PEGENSHDKSSSERS
580 590 600 610 620
640 650 660 670 680
pF1KA0 DQGNTAATQTEVPSLVVKKEET---VEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSA
:. . . ...:. : :. . .:: .: . ..:.. :.
NP_078 TPPYLFPEYPEASKNTGQNREVSILYPGAKDQRQGS-LLPEELEDQMPRLVAEESNRGST
630 640 650 660 670
690 700 710 720 730 740
pF1KA0 DDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTE
. .:. . .... . :. . : .... : . . :.
NP_078 T---INKEEVNKGPFVAVVGVAKGVRDSGAPIQLIPFNREELAERRKAVESWNPVPYSVA
680 690 700 710 720 730
750 760 770 780 790 800
pF1KA0 TDAV---FLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECS--QCSNNE
. :. . :. : :: : . . .. .:.:.::. :..: :: . : . .:
NP_078 SAAIPAAAIGEKARGYEESEGHNTPKLKNQ-RELEELKRTTEKLERVLAERNLFQQKVEE
740 750 760 770 780 790
810 820 830 840 850 860
pF1KA0 SKSEMDEMAVQLDDVFRQLDKCSIERDQ--YKSEVEL--LEMEKSQIRSQCEELKTEVEQ
..: .. .. : ..: : .. . : :. .. . : . .... :. : : ..
NP_078 LEQERNHWQSEFKKVQHELVIYSTQEAEGLYWSKKHMGYRQAEFQILKAELERTKEEKQE
800 810 820 830 840 850
870 880 890 900 910
pF1KA0 LKSTNQQTATDVSTSSNIEESVNHMDGESL-----KLRSLRVNVGQLLAMIVPDLDLQQV
:: ..: : . .. . : .:..: :: ::..:. ::. ..: :.:...
NP_078 LKEKLKETETHLEMLQKAQVSYRTPEGDDLERALAKLTRLRIHVSYLLTSVLPHLELREI
860 870 880 890 900 910
920 930
pF1KA0 NYDVDVVDEILGQVVEQMSEISST
.:: . :: :: :.:
NP_078 GYDSEQVDGILYTVLEANHILD
920 930
>>XP_016885333 (OMIM: 300970) PREDICTED: MORC family CW- (808 aa)
initn: 1150 init1: 441 opt: 1527 Z-score: 1012.7 bits: 198.5 E(85289): 1.1e-49
Smith-Waterman score: 1545; 36.4% identity (63.0% similar) in 833 aa overlap (72-887:1-783)
50 60 70 80 90 100
pF1KA0 DPDVNAKQIWIDKTVINDHICLTFTDNGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGLYG
:: :::.::::::.::: ... :.:..:
XP_016 MTPHKLHRMLSFGFTDKVIKKSQCPIGVFG
10 20 30
110 120 130 140 150 160
pF1KA0 NGFKSGSMRLGKDAIVFTKNGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKH-RQMINLA
::::::::::::::.:::::: ...:::::::::: ..:. :.:::: ::.. ..::
XP_016 NGFKSGSMRLGKDALVFTKNGGTLTVGLLSQTYLECVQAQAVIVPIVPFNQQNKKMIITE
40 50 60 70 80 90
170 180 190 200 210
pF1KA0 ESKASLAAILEHSLFSTEQKLLAELDAIIGKKGTRIIIWNLRSYKNA-TEFDFEKDKYDI
.: :: :::..:.:. :. :::..::: ::::::..:::.: ::. .:.::. :.:::
XP_016 DSLPSLEAILNYSIFNRENDLLAQFDAIPGKKGTRVLIWNIRRNKNGKSELDFDTDQYDI
100 110 120 130 140 150
220 230 240 250 260 270
pF1KA0 RIPEDLDEITGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVS
. :.: : .: ::..:::::.:.:::.::::.:.:: .:: ::...
XP_016 LVS-DFDTEEKMTGGVTSE-----LPETEYSLRAFCGILYMKPRMKIFLRQKKVTTQMIA
160 170 180 190 200
280 290 300 310 320 330
pF1KA0 KSLAYIERDVYRPKFLSKTVRITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRAN-N
:::: .: :.:.: : .: :::::::.:.:....:::::: :::::..::::::.. . .
XP_016 KSLANVEYDTYKPTFTNKQVRITFGFSCKNSNQFGIMMYHNNRLIKSFEKVGCQVKPTRG
210 220 230 240 250 260
340 350 360 370 380 390
pF1KA0 MGVGVVGIIECNFLKPTHNKQDFDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLP
::::.:.::::::::..:::::.::.::::::.::..::: ::.: . : : .
XP_016 EGVGVIGVIECNFLKPAYNKQDFEYTKEYRLTINALAQKLNAYWKEKTSQDNFE--TSTV
270 280 290 300 310 320
400 410 420 430 440 450
pF1KA0 VEDIQKRPDQTWVQCDACLKWRKLPDGMD--QLPEKWYCSNNPDPQFRNCEVPEEPE--D
.. : : ::::::::: :::::::: .: .:: .:.: : :..: : :::: : :
XP_016 ARPIPKVPDQTWVQCDECLKWRKLPGKIDPSMLPARWFCYYNSHPKYRRCSVPEEQELTD
330 340 350 360 370 380
460 470 480 490 500 510
pF1KA0 EDLVHPTYEKTYKKTNKEKFRIRQPEMIPRINAELLFRPTALSTPSFSSPKESVPRRHLS
::: .:..:.. ... . .: : . ::.: . . ....
XP_016 EDLC-------LSKAKKQEQTVEEKKKMPMENE---------NHQVFSNPPKILTVQEMA
390 400 410 420
520 530 540 550 560 570
pF1KA0 EGTNSYATRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDD
: :. . . :. :. : .. .: : . . :... ..::... . :..
XP_016 -GLNNKTIGYEGIHS--PSVLPSGGEESRSPSLQLKPLDSSVLQFSSKYKWIL--GEEPV
430 440 450 460 470 480
580 590 600 610 620 630
pF1KA0 EDVIILEENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQ
: :. : :..:.. : . .:: . : . : :... ..:: :
XP_016 EKRRRLQ-NEMTTPSLDYS--MPAPYRRVE---APVAY-----PEGENSHDKSSSERSTP
490 500 510 520 530
640 650 660 670 680 690
pF1KA0 GNTAATQTEVPSLVVKKEET---VEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADD
:. . . ...:. : :. . .:: .: . ..:.. :.
XP_016 PYLFPEYPEASKNTGQNREVSILYPGAKDQRQGS-LLPEELEDQMPRLVAEESNRGSTT-
540 550 560 570 580
700 710 720 730 740 750
pF1KA0 AGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETD
. .:. . .... . :. . : .... : . . :. .
XP_016 --INKEEVNKGPFVAVVGVAKGVRDSGAPIQLIPFNREELAERRKAVESWNPVPYSVASA
590 600 610 620 630 640
760 770 780 790 800
pF1KA0 AV---FLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSE
:. . :. : :: : . . .. .:.:.::. :..: :: : ...
XP_016 AIPAAAIGEKARGYEESEGHNTPKLKNQ-RELEELKRTTEKLERVLAE-----RNLFQQK
650 660 670 680 690 700
810 820 830 840 850 860
pF1KA0 MDEMAVQLDDVFRQLDKCSIERDQYKS-EVELLEMEKSQI---RSQCEELKTEVEQLKST
..:. . . .. : . : :.. :.: : :... ... . ::.:.:. :
XP_016 VEELEQERNHWQSEFKKVQHELVIYSTQEAEGLYWSKKHMGYRQAEFQILKAELERTKEE
710 720 730 740 750 760
870 880 890 900 910 920
pF1KA0 NQQTATDVSTSSNIEESVNHMDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDE
.:. .. . . : ... .:
XP_016 KQELKEKLKETETHLEMLQKAQGFGKAYAATYPRQLSPYFCPPSLGAS
770 780 790 800
>>XP_005262247 (OMIM: 300970) PREDICTED: MORC family CW- (845 aa)
initn: 1212 init1: 441 opt: 1527 Z-score: 1012.4 bits: 198.5 E(85289): 1.2e-49
Smith-Waterman score: 1640; 36.5% identity (63.2% similar) in 884 aa overlap (72-931:1-839)
50 60 70 80 90 100
pF1KA0 DPDVNAKQIWIDKTVINDHICLTFTDNGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGLYG
:: :::.::::::.::: ... :.:..:
XP_005 MTPHKLHRMLSFGFTDKVIKKSQCPIGVFG
10 20 30
110 120 130 140 150 160
pF1KA0 NGFKSGSMRLGKDAIVFTKNGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKH-RQMINLA
::::::::::::::.:::::: ...:::::::::: ..:. :.:::: ::.. ..::
XP_005 NGFKSGSMRLGKDALVFTKNGGTLTVGLLSQTYLECVQAQAVIVPIVPFNQQNKKMIITE
40 50 60 70 80 90
170 180 190 200 210
pF1KA0 ESKASLAAILEHSLFSTEQKLLAELDAIIGKKGTRIIIWNLRSYKNA-TEFDFEKDKYDI
.: :: :::..:.:. :. :::..::: ::::::..:::.: ::. .:.::. :.:::
XP_005 DSLPSLEAILNYSIFNRENDLLAQFDAIPGKKGTRVLIWNIRRNKNGKSELDFDTDQYDI
100 110 120 130 140 150
220 230 240 250 260 270
pF1KA0 RIPEDLDEITGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVS
. :.: : .: ::..:::::.:.:::.::::.:.:: .:: ::...
XP_005 LVS-DFDTEEKMTGGVTSE-----LPETEYSLRAFCGILYMKPRMKIFLRQKKVTTQMIA
160 170 180 190 200
280 290 300 310 320 330
pF1KA0 KSLAYIERDVYRPKFLSKTVRITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRAN-N
:::: .: :.:.: : .: :::::::.:.:....:::::: :::::..::::::.. . .
XP_005 KSLANVEYDTYKPTFTNKQVRITFGFSCKNSNQFGIMMYHNNRLIKSFEKVGCQVKPTRG
210 220 230 240 250 260
340 350 360 370 380 390
pF1KA0 MGVGVVGIIECNFLKPTHNKQDFDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLP
::::.:.::::::::..:::::.::.::::::.::..::: ::.: . : : .
XP_005 EGVGVIGVIECNFLKPAYNKQDFEYTKEYRLTINALAQKLNAYWKEKTSQDNFE--TSTV
270 280 290 300 310 320
400 410 420 430 440 450
pF1KA0 VEDIQKRPDQTWVQCDACLKWRKLPDGMD--QLPEKWYCSNNPDPQFRNCEVPEEPE--D
.. : : ::::::::: :::::::: .: .:: .:.: : :..: : :::: : :
XP_005 ARPIPKVPDQTWVQCDECLKWRKLPGKIDPSMLPARWFCYYNSHPKYRRCSVPEEQELTD
330 340 350 360 370 380
460 470 480 490 500 510
pF1KA0 EDLVHPTYEKTYKKTNKEKFRIRQPEMIPRINAELLFRPTALSTPSFSSPKESVPRRHLS
::: .:..:.. ... . .: : . ::.: . . ....
XP_005 EDLC-------LSKAKKQEQTVEEKKKMPMENE---------NHQVFSNPPKILTVQEMA
390 400 410 420
520 530 540 550 560 570
pF1KA0 EGTNSYATRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDD
: :. . . :. :. : .. .: : . . :... ..::... . :..
XP_005 -GLNNKTIGYEGIHS--PSVLPSGGEESRSPSLQLKPLDSSVLQFSSKYKWIL--GEEPV
430 440 450 460 470 480
580 590 600 610 620 630
pF1KA0 EDVIILEENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQ
: :. : :..:. .: . .:: . : . : :... ..:: :
XP_005 EKRRRLQ-NEMTTPSLDY--SMPAPYRRVE---APVAY-----PEGENSHDKSSSERSTP
490 500 510 520 530
640 650 660 670 680 690
pF1KA0 GNTAATQTEVPSLVVKKEET---VEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADD
:. . . ...:. : :. . .:: .: . ..:.. :.
XP_005 PYLFPEYPEASKNTGQNREVSILYPGAKDQRQGS-LLPEELEDQMPRLVAEESNRGSTT-
540 550 560 570 580
700 710 720 730 740 750
pF1KA0 AGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETD
. .:. . .... . :. . : .... : . . :. .
XP_005 --INKEEVNKGPFVAVVGVAKGVRDSGAPIQLIPFNREELAERRKAVESWNPVPYSVASA
590 600 610 620 630 640
760 770 780 790 800
pF1KA0 AV---FLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECS--QCSNNESK
:. . :. : :: : . . .. .:.:.::. :..: :: . : . .: .
XP_005 AIPAAAIGEKARGYEESEGHNTPKLKNQ-RELEELKRTTEKLERVLAERNLFQQKVEELE
650 660 670 680 690 700
810 820 830 840 850 860
pF1KA0 SEMDEMAVQLDDVFRQLDKCSIERDQ--YKSEVEL--LEMEKSQIRSQCEELKTEVEQLK
.: .. .. : ..: : .. . : :. .. . : . .... :. : : ..::
XP_005 QERNHWQSEFKKVQHELVIYSTQEAEGLYWSKKHMGYRQAEFQILKAELERTKEEKQELK
710 720 730 740 750 760
870 880 890 900 910
pF1KA0 STNQQTATDVSTSSNIEESVNHMDGESL-----KLRSLRVNVGQLLAMIVPDLDLQQVNY
..: : . .. . : .:..: :: ::..:. ::. ..: :.:....:
XP_005 EKLKETETHLEMLQKAQVSYRTPEGDDLERALAKLTRLRIHVSYLLTSVLPHLELREIGY
770 780 790 800 810 820
920 930
pF1KA0 DVDVVDEILGQVVEQMSEISST
: . :: :: :.:
XP_005 DSEQVDGILYTVLEANHILD
830 840
939 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 02:01:21 2016 done: Sat Nov 5 02:01:23 2016
Total Scan time: 10.370 Total Display time: 0.340
Function used was FASTA [36.3.4 Apr, 2011]