Result of FASTA (ccds) for
pF1KA0015
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0015, 454 aa
1>>>pF1KA0015 454 - 454 aa - 454 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5043+/-0.000704; mu= 12.9600+/- 0.043
mean_var=101.9882+/-20.049, 0's: 0 Z-trim(112.6): 21 B-trim: 0 in 0/53
Lambda= 0.126999
statistics sampled from 13305 (13325) to 13305 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.751), E-opt: 0.2 (0.409), width: 16
Scan time: 2.380
The best scores are: opt bits E(32554)
CCDS13796.1 PPM1F gene_id:9647|Hs108|chr22 ( 454) 3023 564.0 1.1e-160
CCDS11613.1 PPM1E gene_id:22843|Hs108|chr17 ( 755) 1130 217.3 4.4e-56
CCDS3629.1 PPM1K gene_id:152926|Hs108|chr4 ( 372) 369 77.7 2.3e-14
CCDS46115.1 PPM1N gene_id:147699|Hs108|chr19 ( 430) 342 72.8 8e-13
CCDS33886.1 PPM1L gene_id:151742|Hs108|chr3 ( 360) 316 67.9 1.9e-11
CCDS1752.1 PPM1G gene_id:5496|Hs108|chr2 ( 546) 310 67.0 5.6e-11
CCDS82868.1 PPM1L gene_id:151742|Hs108|chr3 ( 233) 302 65.3 7.7e-11
>>CCDS13796.1 PPM1F gene_id:9647|Hs108|chr22 (454 aa)
initn: 3023 init1: 3023 opt: 3023 Z-score: 2998.1 bits: 564.0 E(32554): 1.1e-160
Smith-Waterman score: 3023; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454)
10 20 30 40 50 60
pF1KA0 MSSGAPQKSSPMASGAEETPGFLDTLLQDFPALLNPEDPLPWKAPGTVLSQEEVEGELAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MSSGAPQKSSPMASGAEETPGFLDTLLQDFPALLNPEDPLPWKAPGTVLSQEEVEGELAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LAMGFLGSRKAPPPLAAALAHEAVSQLLQTDLSEFRKLPREEEEEEEDDDEEEKAPVTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 LAMGFLGSRKAPPPLAAALAHEAVSQLLQTDLSEFRKLPREEEEEEEDDDEEEKAPVTLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 DAQSLAQSFFNRLWEVAGQWQKQVPLAARASQRQWLVSIHAIRNTRRKMEDRHVSLPSFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 DAQSLAQSFFNRLWEVAGQWQKQVPLAARASQRQWLVSIHAIRNTRRKMEDRHVSLPSFN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 QLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPELPTDPEGALREAFRRTDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 QLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPELPTDPEGALREAFRRTDQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 MFLRKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MFLRKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 ARIEALGGFVSHMDCWRVNGTLAVSRAIGDVFQKPYVSGEADAASRALTGSEDYLLLACD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 ARIEALGGFVSHMDCWRVNGTLAVSRAIGDVFQKPYVSGEADAASRALTGSEDYLLLACD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 GFFDVVPHQEVVGLVQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVVFLRDPQELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 GFFDVVPHQEVVGLVQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVVFLRDPQELL
370 380 390 400 410 420
430 440 450
pF1KA0 EGGNQGEGDPQAEGRRQDLPSSLPEPETQAPPRS
::::::::::::::::::::::::::::::::::
CCDS13 EGGNQGEGDPQAEGRRQDLPSSLPEPETQAPPRS
430 440 450
>>CCDS11613.1 PPM1E gene_id:22843|Hs108|chr17 (755 aa)
initn: 1163 init1: 1070 opt: 1130 Z-score: 1120.4 bits: 217.3 E(32554): 4.4e-56
Smith-Waterman score: 1244; 47.1% identity (70.4% similar) in 452 aa overlap (13-451:102-537)
10 20 30 40
pF1KA0 MSSGAPQKSSPMASGAEETPGFLDTLLQDFPALLNPEDPLPW
:. : .:: . . : : : :::
CCDS11 TVAATEEGDQEQDPEPEEEAAVEGEEEEEGAATAAAAPG--HSAVPPPPPQLPPLPPLP-
80 90 100 110 120
50 60 70 80 90 100
pF1KA0 KAPGTVLSQEEVEGELAELAMGFLGSRKAPPPLAAALAHEAVSQLLQTDLSEFRKLPREE
. . ...:::::: .: . : . . : ::::::. . ...::.::: .:.:
CCDS11 RPLSERITREEVEGESLDLCLQQLYKYNCPSFLAAALARATSDEVLQSDLSAHY-IPKE-
130 140 150 160 170 180
110 120 130 140 150 160
pF1KA0 EEEEEDDDEEEKAPVTLLDAQSLAQSFFNRLWEVAGQWQKQVPLAARASQRQWLVSIHAI
: : . . .. .::.: :..: :. .: :. :: : : . .:::::
CCDS11 -----TDGTEGTVEI---ETVKLARSVFSKLHEICCSWVKDFPLR-RRPQLYYETSIHAI
190 200 210 220 230
170 180 190 200 210 220
pF1KA0 RNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPE
.: ::::::.:: .:.::.::.: : ..::::::::::::::: ::..:.:.: .::
CCDS11 KNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYFAVFDGHGGVDAAIYASIHLHVNLVRQEM
240 250 260 270 280 290
230 240 250 260 270 280
pF1KA0 LPTDPEGALREAFRRTDQMFLRKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQ
.: :: :: .::: ::. :..:: :: :. ::::: ..: : :::::.:::::.::..
CCDS11 FPHDPAEALCRAFRVTDERFVQKAARESLRCGTTGVVTFIRGNMLHVAWVGDSQVMLVRK
300 310 320 330 340 350
290 300 310 320 330 340
pF1KA0 GQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTLAVSRAIGDVFQKPYVSGEAD
::.:.::.::.:.:.::: ::::::: : . :::::.:.:::::::. .:::. :.::
CCDS11 GQAVELMKPHKPDREDEKQRIEALGGCVVWFGAWRVNGSLSVSRAIGDAEHKPYICGDAD
360 370 380 390 400 410
350 360 370 380 390 400
pF1KA0 AASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQGSGLRVAEELVAAARERGS
.:: .: :.::::.::::::.:.: .:.: .:..:: ...:.. ::..:::.::. ::
CCDS11 SASTVLDGTEDYLILACDGFYDTVNPDEAVKVVSDHLKENNGDSSMVAHKLVASARDAGS
420 430 440 450 460 470
410 420 430 440
pF1KA0 HDNITVMVVFLRD-------------PQELLEGGNQGEGDPQAEGRRQDLPSSLPEPETQ
:::::.:::::: .. ..::.. :: . . . : :. . .
CCDS11 SDNITVIVVFLRDMNKAVNVSEESDWTENSFQGGQEDGGDDKENHGECKRP--WPQHQCS
480 490 500 510 520 530
450
pF1KA0 APPRS
::
CCDS11 APADLGYDGRVDSFTDRTSLSPGSQINVLEDPGYLDLTQIEASKPHSAQFLLPVEMFGPG
540 550 560 570 580 590
>>CCDS3629.1 PPM1K gene_id:152926|Hs108|chr4 (372 aa)
initn: 275 init1: 154 opt: 369 Z-score: 371.4 bits: 77.7 E(32554): 2.3e-14
Smith-Waterman score: 369; 36.4% identity (58.5% similar) in 258 aa overlap (166-411:104-344)
140 150 160 170 180 190
pF1KA0 VAGQWQKQVPLAARASQRQWLVSIHAIRNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFA
:.. ::: .: :: .: : :::
CCDS36 PILLPPSIKYGKPIPKISLENVGCASQIGKRKENEDRF----DFAQL---TDEV--LYFA
80 90 100 110 120
200 210 220 230 240 250
pF1KA0 VFDGHGGVDAARYAAVHVHTNAARQPELPTDP--EGALREAFRRTDQMFLRKAKRER---
:.::::: :: . :.: . . :: . : : :: . :. : .:.
CCDS36 VYDGHGGPAAADF--CHTHMEKCIMDLLPKEKNLETLLTLAFLEIDKAFSSHARLSADAT
130 140 150 160 170 180
260 270 280 290 300
pF1KA0 -LQSGTTGVCALIA-GATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGG
: ::::.. ::. : : :: .:::..:: ..:. .:: : :::.::: ::. ::
CCDS36 LLTSGTTATVALLRDGIELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGG
190 200 210 220 230 240
310 320 330 340 350 360
pF1KA0 FVS--HMDCWRVNGTLAVSRAIGDV-FQKPYVSGEADAASRALTGSED-YLLLACDGFFD
::. . .::: ::..:.:::. .. : .: .. : ..: .:.:. ::.
CCDS36 FVAWNSLGQPHVNGRLAMTRSIGDLDLKTSGVIAEPETKRIKLHHADDSFLVLTTDGINF
250 260 270 280 290 300
370 380 390 400 410 420
pF1KA0 VVPHQEVVGLV-QSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVVFLRDPQELLEGG
.: ::. .: : : . .:. .. : . :..:: :..::
CCDS36 MVNSQEICDFVNQCHDPNE------AAHAVTEQAIQYGTEDNSTAVVVPFGAWGKYKNSE
310 320 330 340 350
430 440 450
pF1KA0 NQGEGDPQAEGRRQDLPSSLPEPETQAPPRS
CCDS36 INFSFSRSFASSGRWA
360 370
>>CCDS46115.1 PPM1N gene_id:147699|Hs108|chr19 (430 aa)
initn: 435 init1: 122 opt: 342 Z-score: 343.7 bits: 72.8 E(32554): 8e-13
Smith-Waterman score: 474; 35.4% identity (56.7% similar) in 390 aa overlap (77-448:2-363)
50 60 70 80 90 100
pF1KA0 TVLSQEEVEGELAELAMGFLGSRKAPPPLAAALAHEAVSQLLQTDLS--EFRKLPREEEE
:.::.. ...:: : . : .: :::::
CCDS46 MAVLARQ-LQRLLWTACKKKEREKEGREEEE
10 20 30
110 120 130 140 150 160
pF1KA0 EEEDDDEEEKAPVTLLDAQSLAQSFFNRLWEVAGQWQKQVPLAARASQRQWLVSIHAIRN
::: . ..: .:: : :: . :..: . ..: :.: :
CCDS46 EEEAGRRAPEGPRSLLTAPRRAQRPHGGA-EASGGLR----FGASAAQ-GW---------
40 50 60 70
170 180 190 200 210 220
pF1KA0 TRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHV--HTNAARQPE
: .::: : . : : :: : . : :::.:::::. :::..: :. :. ::
CCDS46 -RARMEDAHCTWLS---LPGL--PPGWALFAVLDGHGGARAARFGARHLPGHVLQELGPE
80 90 100 110 120
230 240 250 260 270
pF1KA0 LPTDPEG---ALREAFRRTDQMFLRKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVIL
:..::: :::.:: .:. ::. . .: :.: :.. :..: :::...:
CCDS46 -PSEPEGVREALRRAFLSADER-LRSLWPRVETGGCTAVVLLVSPRFLYLAHCGDSRAVL
130 140 150 160 170 180
280 290 300 310 320 330
pF1KA0 VQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTLAVSRAIGDVFQK--P--
. : :. : ::: : :. ::.: :: . . ::.:.::::::.:: : :
CCDS46 SRAGAVAFSTEDHRPLRPRERERIHAAGGTIRRR---RVEGSLAVSRALGDFTYKEAPGR
190 200 210 220 230 240
340 350 360 370 380 390
pF1KA0 -----YVSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQGSGLRVA
::.: ..:. : . ....::: :: .:.: ..::: :.: . : :
CCDS46 PPELQLVSAEPEVAALARQAEDEFMLLASDGVWDTVSGAALAGLVASRLRLGLAPELLCA
250 260 270 280 290 300
400 410 420 430 440
pF1KA0 EELVAAARERGSHDNIT-VMVVFLRDPQELLEGGNQGEGDPQAEGRR-QDLPSSLPEPET
. :. . .:: ::.: ..: : :. :. . . : : : .: .: .: .
CCDS46 Q-LLDTCLCKGSLDNMTCILVCFPGAPRPSEEAIRRELALDAALGCRIAELCASAQKPPS
310 320 330 340 350 360
450
pF1KA0 QAPPRS
CCDS46 LNTVFRTLASEDIPDLPPGGGLDCKATVIAEVYSQICQVSEECGEKGQDGAGKSNPTHLG
370 380 390 400 410 420
>>CCDS33886.1 PPM1L gene_id:151742|Hs108|chr3 (360 aa)
initn: 367 init1: 155 opt: 316 Z-score: 319.1 bits: 67.9 E(32554): 1.9e-11
Smith-Waterman score: 391; 31.3% identity (60.1% similar) in 278 aa overlap (157-421:93-359)
130 140 150 160 170 180
pF1KA0 QSFFNRLWEVAGQWQKQVPLAARASQRQWLVSIHAIRNTRRKMEDRHVSLPSFNQLFGLS
:....:.. : .:::: :. : :.
CCDS33 VAEIMQNDRLGGLDVLEAEFSKTWEFKNHNVAVYSIQGRRDHMEDR------FEVLTDLA
70 80 90 100 110
190 200 210 220 230
pF1KA0 DPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQ--PELPTDPEGA-------LREAFRR
. .. . :..:::::: ::.:. .. .: .: . : :.. :.. .
CCDS33 NKTHPSIFGIFDGHGGETAAEYVKSRL-PEALKQHLQDYEKDKENSVLSYQTILEQQILS
120 130 140 150 160 170
240 250 260 270 280 290
pF1KA0 TDQMFLRKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQ-GQVVKLMEPHRPER
:. .:.: ..::: . ::.. : :: .:::. .: .. :... : . :.: .
CCDS33 IDREMLEKLTVSYDEAGTTCLIALLSDKDLTVANVGDSRGVLCDKDGNAIPLSHDHKPYQ
180 190 200 210 220 230
300 310 320 330 340 350
pF1KA0 QDEKARIEALGGFVSHMDCWRVNGTLAVSRAIGDVFQKPY--VSGEADAASRALTGSE-D
:. ::. :::.: :::.: ::.::..:: : : . : . : . .
CCDS33 LKERKRIKRAGGFISFNGSWRVQGILAMSRSLGDYPLKNLNVVIPDPDILTFDLDKLQPE
240 250 260 270 280 290
360 370 380 390 400 410
pF1KA0 YLLLACDGFFDVVPHQEVVGLVQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVVFL
...:: ::..:. ..:.: ... .: . . . :. .: . :: :::::::: .
CCDS33 FMILASDGLWDAFSNEEAVRFIKERLDEPHFG----AKSIVLQSFYRGCPDNITVMVVKF
300 310 320 330 340 350
420 430 440 450
pF1KA0 RDPQELLEGGNQGEGDPQAEGRRQDLPSSLPEPETQAPPRS
:. .. :
CCDS33 RNSSKTEEQ
360
>>CCDS1752.1 PPM1G gene_id:5496|Hs108|chr2 (546 aa)
initn: 372 init1: 146 opt: 310 Z-score: 310.5 bits: 67.0 E(32554): 5.6e-11
Smith-Waterman score: 321; 33.3% identity (62.2% similar) in 246 aa overlap (215-437:286-521)
190 200 210 220 230 240
pF1KA0 LSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPELPTDPEGALREAFRRTDQMFL-
.. :.. : : : : .. .. ..:..
CCDS17 FFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEEEEMMVP
260 270 280 290 300 310
250 260 270 280 290 300
pF1KA0 -RKAKRER-LQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKA
..:.: .::::.: ::: : : :: :::. .. . :... . :.:: . : :
CCDS17 GMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELA
320 330 340 350 360 370
310 320 330 340 350
pF1KA0 RIEALGGFVSHMDCWRVNGTLAVSRAIGDVFQK-----P----YVSGEADAASRALTGSE
::. :: :. :: :::: : .:::::: : : : ..:. : .:: ..
CCDS17 RIKNAGGKVT-MDG-RVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDH
380 390 400 410 420 430
360 370 380 390 400
pF1KA0 DYLLLACDGFFDVVPHQEVVGLVQSHLTRQQGSG-LR----VAEELVA---AARERGSH-
.....::::...:. :::: ..::...... .: :: ..:::. : :.
CCDS17 EFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGT
440 450 460 470 480 490
410 420 430 440 450
pF1KA0 --DNITVMVVFLRDPQELLEGGNQGEGDPQAEGRRQDLPSSLPEPETQAPPRS
::.: ... .. :. : .: .:.. :.:.
CCDS17 GCDNMTCIIICFK-PR------NTAELQPES-GKRKLEEVLSTEGAEENGNSDKKKKAKR
500 510 520 530 540
CCDS17 D
>>CCDS82868.1 PPM1L gene_id:151742|Hs108|chr3 (233 aa)
initn: 256 init1: 155 opt: 302 Z-score: 308.1 bits: 65.3 E(32554): 7.7e-11
Smith-Waterman score: 302; 32.3% identity (61.0% similar) in 195 aa overlap (231-421:42-232)
210 220 230 240 250 260
pF1KA0 GGVDAARYAAVHVHTNAARQPELPTDPEGALREAFRRTDQMFLRKAKRERLQSGTTGVCA
:.. . :. .:.: ..::: . :
CCDS82 VKSRLPEALKQHLQDYEKDKENSVLSYQTILEQQILSIDREMLEKLTVSYDEAGTTCLIA
20 30 40 50 60 70
270 280 290 300 310
pF1KA0 LIAGATLHVAWLGDSQVILVQQ-GQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVN
:.. : :: .:::. .: .. :... : . :.: . :. ::. :::.: :::.
CCDS82 LLSDKDLTVANVGDSRGVLCDKDGNAIPLSHDHKPYQLKERKRIKRAGGFISFNGSWRVQ
80 90 100 110 120 130
320 330 340 350 360 370
pF1KA0 GTLAVSRAIGDVFQKPY--VSGEADAASRALTGSE-DYLLLACDGFFDVVPHQEVVGLVQ
: ::.::..:: : : . : . : . ....:: ::..:. ..:.: ...
CCDS82 GILAMSRSLGDYPLKNLNVVIPDPDILTFDLDKLQPEFMILASDGLWDAFSNEEAVRFIK
140 150 160 170 180 190
380 390 400 410 420 430
pF1KA0 SHLTRQQGSGLRVAEELVAAARERGSHDNITVMVVFLRDPQELLEGGNQGEGDPQAEGRR
.: . . . :. .: . :: :::::::: .:. .. :
CCDS82 ERLDEPHFG----AKSIVLQSFYRGCPDNITVMVVKFRNSSKTEEQ
200 210 220 230
440 450
pF1KA0 QDLPSSLPEPETQAPPRS
454 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 17:53:15 2016 done: Wed Nov 2 17:53:16 2016
Total Scan time: 2.380 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]