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[1][TOP]
>UniRef100_UPI0000437D6C ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature
           sensitivity complementing) n=1 Tax=Danio rerio
           RepID=UPI0000437D6C
          Length = 1058

 Score =  139 bits (349), Expect = 1e-31
 Identities = 75/147 (51%), Positives = 91/147 (61%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           K+ VVVL N SL  QT +   C    +K +     G+FG +F DFG + +V D NGEQP 
Sbjct: 158 KFQVVVLTNSSLDEQTRIGEFCHSNGIKLIVADTRGLFGQLFCDFGEEMIVFDTNGEQPL 217

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S MIS IT +     VV CLDE RH FE+GD+VTFTEVQG T LN     EIK LGPYTF
Sbjct: 218 SAMISMITKDSAG--VVTCLDEARHGFESGDYVTFTEVQGMTELNGCDPVEIKTLGPYTF 275

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     + ++   YVRGG  TQVKMP
Sbjct: 276 SIC----DTSSFSDYVRGGIVTQVKMP 298

[2][TOP]
>UniRef100_A7SSG6 Ubiquitin-activating enzyme E1 n=1 Tax=Nematostella vectensis
           RepID=A7SSG6_NEMVE
          Length = 1007

 Score =  138 bits (348), Expect = 2e-31
 Identities = 76/147 (51%), Positives = 93/147 (63%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           K+ VVVL   SL  Q  +   C    +K +     G+FG IF DFG  F V D NGEQP 
Sbjct: 111 KFQVVVLTESSLEEQLWISDFCHSKGIKLIISDTKGLFGQIFCDFGESFTVVDTNGEQPV 170

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S MISA++ +     VV CLDEQRH +ETGD+VTF EVQG T LN+ + REIKVLGPYTF
Sbjct: 171 SNMISAVSKDAQG--VVTCLDEQRHGYETGDYVTFCEVQGMTELNNCEPREIKVLGPYTF 228

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     + ++   YVRGG  TQVKMP
Sbjct: 229 SI----GDTSSYSDYVRGGIVTQVKMP 251

[3][TOP]
>UniRef100_Q6P9P3 Ubiquitin-activating enzyme E1 n=1 Tax=Danio rerio
           RepID=Q6P9P3_DANRE
          Length = 1058

 Score =  137 bits (346), Expect = 3e-31
 Identities = 75/147 (51%), Positives = 90/147 (61%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           K+ VVVL N SL  QT +   C    +K +     G+FG +F DFG   +V D NGEQP 
Sbjct: 158 KFQVVVLTNSSLDEQTRIGEFCHSNGIKLIVADTRGLFGQLFCDFGEVMIVFDTNGEQPL 217

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S MIS IT +     VV CLDE RH FE+GD+VTFTEVQG T LN     EIK LGPYTF
Sbjct: 218 SAMISMITKDSAG--VVTCLDEARHGFESGDYVTFTEVQGMTELNGCDPVEIKTLGPYTF 275

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     + ++   YVRGG  TQVKMP
Sbjct: 276 SIC----DTSSFSDYVRGGIVTQVKMP 298

[4][TOP]
>UniRef100_Q6P285 Ubiquitin-activating enzyme E1 n=1 Tax=Xenopus laevis
           RepID=Q6P285_XENLA
          Length = 1060

 Score =  135 bits (341), Expect = 1e-30
 Identities = 73/146 (50%), Positives = 92/146 (63%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + +V+L   SL  Q  +   C   D+KF+     G+FG +F DFG + VV D NGEQP S
Sbjct: 159 FQLVILTASSLEEQLQIGDFCHSHDIKFIVADTKGLFGQLFCDFGKEMVVMDPNGEQPLS 218

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            MIS IT ++    VV CLDE RH FETGD VTFTEV+G T LN  +  EIKVLGPYTF+
Sbjct: 219 AMISMITKDNPG--VVTCLDEARHGFETGDFVTFTEVRGMTELNGCEPVEIKVLGPYTFS 276

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           + G     ++   Y+RGG  +QVKMP
Sbjct: 277 ICG----TSSFSDYIRGGIVSQVKMP 298

[5][TOP]
>UniRef100_UPI00006A40A0 PREDICTED: similar to ubiquitin-like modifier activating enzyme 1
           n=1 Tax=Ciona intestinalis RepID=UPI00006A40A0
          Length = 1087

 Score =  135 bits (340), Expect = 2e-30
 Identities = 70/148 (47%), Positives = 94/148 (63%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           +++ VVVL + SLA Q  +     ++++  +    +G+FG IF DF   F V D NGE P
Sbjct: 170 SQFQVVVLTSSSLAEQLRISDFTHKSNIYLIVANTFGLFGQIFCDFSSNFTVYDTNGENP 229

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
           +S MISAIT  +  + +VACLDE RH FE+GD V F EV+G  GLND + R+I VLGPYT
Sbjct: 230 QSAMISAITKNEKGEGIVACLDETRHGFESGDFVKFHEVKGMDGLNDSEPRKINVLGPYT 289

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F +     +++    Y RGG ATQVKMP
Sbjct: 290 FNI----GDISQYNNYDRGGIATQVKMP 313

[6][TOP]
>UniRef100_Q9DEE8 Ubiquitin-activating enzyme E1 n=1 Tax=Xenopus laevis
           RepID=Q9DEE8_XENLA
          Length = 1059

 Score =  135 bits (340), Expect = 2e-30
 Identities = 73/146 (50%), Positives = 92/146 (63%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + +V+L   SL  Q  V   C   D+KF+     G+FG +F DFG + VV D NGEQP S
Sbjct: 158 FQLVILTGSSLEEQLQVGDFCHSHDIKFIVADTKGLFGQLFCDFGKEMVVMDPNGEQPLS 217

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            MIS IT ++    VV CLDE RH FETGD VTFTEV+G T LN  +  EIKVLGPYTF+
Sbjct: 218 AMISMITKDNPG--VVTCLDEARHGFETGDFVTFTEVRGMTELNGCEPVEIKVLGPYTFS 275

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     + ++   Y+RGG  +QVKMP
Sbjct: 276 IC----DTSSFSDYIRGGIVSQVKMP 297

[7][TOP]
>UniRef100_Q801S7 Ubiquitin-activating enzyme E1 n=1 Tax=Xenopus laevis
           RepID=Q801S7_XENLA
          Length = 1059

 Score =  135 bits (340), Expect = 2e-30
 Identities = 73/146 (50%), Positives = 92/146 (63%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + +V+L   SL  Q  V   C   D+KF+     G+FG +F DFG + VV D NGEQP S
Sbjct: 158 FQLVILTGSSLEEQLQVGDFCHSHDIKFIVADTKGLFGQLFCDFGKEMVVMDPNGEQPLS 217

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            MIS IT ++    VV CLDE RH FETGD VTFTEV+G T LN  +  EIKVLGPYTF+
Sbjct: 218 AMISMITKDNPG--VVTCLDEARHGFETGDFVTFTEVRGMTELNGCEPVEIKVLGPYTFS 275

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     + ++   Y+RGG  +QVKMP
Sbjct: 276 IC----DTSSFSDYIRGGIVSQVKMP 297

[8][TOP]
>UniRef100_Q9I943 Ubiquitin-activating enzyme E1 n=1 Tax=Carassius auratus
           RepID=Q9I943_CARAU
          Length = 1058

 Score =  134 bits (336), Expect = 5e-30
 Identities = 74/147 (50%), Positives = 89/147 (60%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           K+ VVVL N SL  Q  +   C    +K +     G+FG +F DFG +  V D NGEQP 
Sbjct: 158 KFQVVVLTNSSLDEQIRLGDFCHSNGIKLIVADTRGLFGQLFCDFGEEMTVFDTNGEQPL 217

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S MIS IT +     VV CLDE RH FE+GD VTFTEVQG T LN  +  EIK LGPYTF
Sbjct: 218 SAMISMITKDSAG--VVTCLDEARHGFESGDFVTFTEVQGMTELNGCEPIEIKTLGPYTF 275

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     + ++   YVRGG  TQVKMP
Sbjct: 276 SIC----DTSSFSDYVRGGIVTQVKMP 298

[9][TOP]
>UniRef100_UPI00006A27B8 Ubiquitin-activating enzyme E1 (A1S9 protein). n=1 Tax=Xenopus
           (Silurana) tropicalis RepID=UPI00006A27B8
          Length = 1010

 Score =  131 bits (329), Expect = 3e-29
 Identities = 72/146 (49%), Positives = 90/146 (61%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + +V+L   ++  Q  V   C   D+KF+     G+FG +F DFG + VV D NGEQP S
Sbjct: 157 FQLVILTAATMEEQLRVGDFCHSHDIKFIVADTRGLFGQLFCDFGKEMVVMDPNGEQPLS 216

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            MIS IT ++    VV CLDE RH FETGD VTFTEV+G T LN  +  EIKVLGPYTF+
Sbjct: 217 AMISMITKDNPG--VVTCLDEARHGFETGDFVTFTEVRGMTELNGCEPVEIKVLGPYTFS 274

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     + +    YVRGG   QVKMP
Sbjct: 275 IC----DTSRFSDYVRGGIVAQVKMP 296

[10][TOP]
>UniRef100_UPI00006A27B7 Ubiquitin-activating enzyme E1 (A1S9 protein). n=1 Tax=Xenopus
           (Silurana) tropicalis RepID=UPI00006A27B7
          Length = 1012

 Score =  131 bits (329), Expect = 3e-29
 Identities = 72/146 (49%), Positives = 90/146 (61%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + +V+L   ++  Q  V   C   D+KF+     G+FG +F DFG + VV D NGEQP S
Sbjct: 157 FQLVILTAATMEEQLRVGDFCHSHDIKFIVADTRGLFGQLFCDFGKEMVVMDPNGEQPLS 216

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            MIS IT ++    VV CLDE RH FETGD VTFTEV+G T LN  +  EIKVLGPYTF+
Sbjct: 217 AMISMITKDNPG--VVTCLDEARHGFETGDFVTFTEVRGMTELNGCEPVEIKVLGPYTFS 274

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     + +    YVRGG   QVKMP
Sbjct: 275 IC----DTSRFSDYVRGGIVAQVKMP 296

[11][TOP]
>UniRef100_UPI0000F2E5FF PREDICTED: similar to ubiquitin-activating enzyme E1 n=1
           Tax=Monodelphis domestica RepID=UPI0000F2E5FF
          Length = 1064

 Score =  130 bits (326), Expect = 7e-29
 Identities = 69/148 (46%), Positives = 90/148 (60%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           + + VVVL N  L  Q  V   C    +K +     G+FG +F DFG + +++D NGEQP
Sbjct: 163 SSFQVVVLTNSPLEEQLRVGQFCHGHGIKLVVADTRGLFGQLFCDFGEEMILTDANGEQP 222

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
            S M+S +T ++    VV CLDE RH FE+GD VTFTEVQG + LN     EIKVLGPYT
Sbjct: 223 LSAMVSMVTKDNPG--VVTCLDEARHGFESGDFVTFTEVQGMSELNGISPMEIKVLGPYT 280

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F++     + A    Y+RGG  TQVK+P
Sbjct: 281 FSIC----DTARFSDYIRGGIVTQVKVP 304

[12][TOP]
>UniRef100_UPI00017B1D1B UPI00017B1D1B related cluster n=1 Tax=Tetraodon nigroviridis
           RepID=UPI00017B1D1B
          Length = 1057

 Score =  130 bits (326), Expect = 7e-29
 Identities = 70/147 (47%), Positives = 90/147 (61%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           K+ VVVL N +L  Q  +   C    +K +     G+FG +F DFG + +V D NGEQP 
Sbjct: 158 KFQVVVLTNSTLDEQQHLGEFCHSKGIKLIVTDTRGLFGQVFCDFGEEMIVYDTNGEQPL 217

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S MIS IT ++    VV CLDE RH FE+GD+VTFTE+QG   LN  +  EIKVLGPYTF
Sbjct: 218 SAMISMITKDNPG--VVTCLDEARHGFESGDYVTFTEIQGMLELNGCQPVEIKVLGPYTF 275

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +      YVRGG  +QVK+P
Sbjct: 276 SIC----DTTGFTDYVRGGIVSQVKIP 298

[13][TOP]
>UniRef100_UPI0000018597 UPI0000018597 related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI0000018597
          Length = 1057

 Score =  130 bits (326), Expect = 7e-29
 Identities = 70/147 (47%), Positives = 90/147 (61%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           K+ VVVL   +L  Q  +   C    +K +     G+FG +F DFG + +V D NGEQP 
Sbjct: 158 KFQVVVLTTSTLDEQQHLGELCHSKGIKLIIADTRGLFGQLFCDFGEEMIVYDTNGEQPL 217

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S MIS IT ++    VV CLDE RH FE+GD+VTFTE+QG T LN  +  EIKVLGPYTF
Sbjct: 218 SAMISMITKDNPG--VVTCLDEARHGFESGDYVTFTEIQGMTELNGCQPVEIKVLGPYTF 275

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +      YVRGG  +QVK+P
Sbjct: 276 SIC----DTTGFTDYVRGGIVSQVKIP 298

[14][TOP]
>UniRef100_Q4RW85 Ubiquitin-activating enzyme E1 (Fragment) n=1 Tax=Tetraodon
           nigroviridis RepID=Q4RW85_TETNG
          Length = 1062

 Score =  130 bits (326), Expect = 7e-29
 Identities = 70/147 (47%), Positives = 90/147 (61%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           K+ VVVL N +L  Q  +   C    +K +     G+FG +F DFG + +V D NGEQP 
Sbjct: 158 KFQVVVLTNSTLDEQQHLGEFCHSKGIKLIVTDTRGLFGQVFCDFGEEMIVYDTNGEQPL 217

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S MIS IT ++    VV CLDE RH FE+GD+VTFTE+QG   LN  +  EIKVLGPYTF
Sbjct: 218 SAMISMITKDNPG--VVTCLDEARHGFESGDYVTFTEIQGMLELNGCQPVEIKVLGPYTF 275

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +      YVRGG  +QVK+P
Sbjct: 276 SIC----DTTGFTDYVRGGIVSQVKIP 298

[15][TOP]
>UniRef100_C7E650 Ubiquitin-activating enzyme E1 (Fragment) n=1 Tax=Monodelphis
           domestica RepID=C7E650_MONDO
          Length = 911

 Score =  130 bits (326), Expect = 7e-29
 Identities = 69/148 (46%), Positives = 90/148 (60%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           + + VVVL N  L  Q  V   C    +K +     G+FG +F DFG + +++D NGEQP
Sbjct: 130 SSFQVVVLTNSPLEEQLRVGQFCHGHGIKLVVADTRGLFGQLFCDFGEEMILTDANGEQP 189

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
            S M+S +T ++    VV CLDE RH FE+GD VTFTEVQG + LN     EIKVLGPYT
Sbjct: 190 LSAMVSMVTKDNPG--VVTCLDEARHGFESGDFVTFTEVQGMSELNGISPMEIKVLGPYT 247

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F++     + A    Y+RGG  TQVK+P
Sbjct: 248 FSIC----DTARFSDYIRGGIVTQVKVP 271

[16][TOP]
>UniRef100_C3ZZI8 Ubiquitin-activating enzyme E1 n=1 Tax=Branchiostoma floridae
           RepID=C3ZZI8_BRAFL
          Length = 1057

 Score =  129 bits (324), Expect = 1e-28
 Identities = 69/148 (46%), Positives = 91/148 (61%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           + + VVVL   SL  Q  +   C +  +K +     G+FG IF DFG  F+VSD  GE+P
Sbjct: 157 SNFQVVVLTESSLEEQLKLGEFCHDKGIKLIVASTKGLFGQIFCDFGEDFLVSDPTGEEP 216

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
            S MISAIT E   D +V  L+E RH  ETGD+VTF E+QG T LN  ++R++KV+GPYT
Sbjct: 217 VSCMISAITKEQ--DGIVTTLEESRHGLETGDYVTFQEIQGMTELNGCEARKVKVMGPYT 274

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F++     +   +  YVRGG A QVK P
Sbjct: 275 FSI----GDTTGLSDYVRGGIAMQVKQP 298

[17][TOP]
>UniRef100_Q5KPX3 Ubiquitin activating enzyme, putative n=1 Tax=Filobasidiella
           neoformans RepID=Q5KPX3_CRYNE
          Length = 1015

 Score =  129 bits (324), Expect = 1e-28
 Identities = 65/146 (44%), Positives = 89/146 (60%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           Y +VVL N ++  Q  +D  CR+  + F++    G+FGS+FNDFG  F   D  GE P S
Sbjct: 127 YQIVVLTNATVRKQVEIDEYCRQKGIYFIAADVRGLFGSVFNDFGKDFACVDPTGENPLS 186

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            MI  + +++ +D +V CLDE RH  E GD VTF+E++G  GLN  + R+I V GPYTF+
Sbjct: 187 GMI--VEIDEDEDAIVTCLDETRHGLEDGDFVTFSEIKGMEGLNGCEPRKISVKGPYTFS 244

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +   R     +G Y  GG  TQVKMP
Sbjct: 245 IGDTR----GLGKYKSGGLFTQVKMP 266

[18][TOP]
>UniRef100_Q560X2 Putative uncharacterized protein n=1 Tax=Filobasidiella neoformans
           RepID=Q560X2_CRYNE
          Length = 1007

 Score =  129 bits (324), Expect = 1e-28
 Identities = 65/146 (44%), Positives = 89/146 (60%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           Y +VVL N ++  Q  +D  CR+  + F++    G+FGS+FNDFG  F   D  GE P S
Sbjct: 127 YQIVVLTNATVRKQVEIDEYCRQKGIYFIAADVRGLFGSVFNDFGKDFACVDPTGENPLS 186

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            MI  + +++ +D +V CLDE RH  E GD VTF+E++G  GLN  + R+I V GPYTF+
Sbjct: 187 GMI--VEIDEDEDAIVTCLDETRHGLEDGDFVTFSEIKGMEGLNGCEPRKISVKGPYTFS 244

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +   R     +G Y  GG  TQVKMP
Sbjct: 245 IGDTR----GLGKYKSGGLFTQVKMP 266

[19][TOP]
>UniRef100_UPI0000E46CFA PREDICTED: similar to ubiquitin-activating enzyme E1 n=1
           Tax=Strongylocentrotus purpuratus RepID=UPI0000E46CFA
          Length = 1054

 Score =  127 bits (319), Expect = 4e-28
 Identities = 66/148 (44%), Positives = 92/148 (62%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           +K+ VVVL   SL  Q  +   C    +  +     G+FG +F DFG  F V D  GE+P
Sbjct: 154 SKFQVVVLTTSSLEAQLRIGDFCHSKGIHLIIADTRGLFGQVFCDFGDDFTVYDSTGEEP 213

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
            SVM+SA++ +D    VV CLDE RH FE+GD+V+F+E++G T LN  + ++IKVLGPYT
Sbjct: 214 MSVMVSAVSKDDQG--VVTCLDESRHGFESGDYVSFSEIKGMTELNGCQPKKIKVLGPYT 271

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F +     + + +  YVRGG  +QVKMP
Sbjct: 272 FDI----GDTSDLSDYVRGGIVSQVKMP 295

[20][TOP]
>UniRef100_C7E644 Ubiquitin-activating enzyme E1 (Fragment) n=1 Tax=Monodelphis
           domestica RepID=C7E644_MONDO
          Length = 984

 Score =  127 bits (318), Expect = 6e-28
 Identities = 68/148 (45%), Positives = 88/148 (59%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           + + VVVL N  L  Q  V   C    +K +     G+FG +F DFG + V+ D NGEQP
Sbjct: 134 SNFQVVVLTNSPLVEQLDVGEFCHSHAIKLVVADTRGLFGQLFCDFGEEMVLIDSNGEQP 193

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
            S M+S +T +     VV CLDE RH FE+GD V+FTE+QG + LN     EIKVLGPYT
Sbjct: 194 LSAMVSMVTKDSPG--VVTCLDETRHGFESGDFVSFTEIQGMSELNSSPPVEIKVLGPYT 251

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F++     +  A   YVRGG  +QVK+P
Sbjct: 252 FSIC----DTTAFSDYVRGGIVSQVKVP 275

[21][TOP]
>UniRef100_Q29504 Ubiquitin-like modifier-activating enzyme 1 n=1 Tax=Oryctolagus
           cuniculus RepID=UBA1_RABIT
          Length = 1058

 Score =  126 bits (317), Expect = 7e-28
 Identities = 66/146 (45%), Positives = 90/146 (61%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL N  L  Q  V   C    +K +     G+FG +F DFG + +++D NGEQP S
Sbjct: 159 FQVVVLTNSPLEDQLRVGEFCHSRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLS 218

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            M+S +T ++    VV CLDE RH FE+GD V+F+EVQG T LN  +  EIKVLGPYTF+
Sbjct: 219 TMVSMVTKDNPG--VVTCLDEARHGFESGDFVSFSEVQGMTELNGNQPIEIKVLGPYTFS 276

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     + +    Y+RGG  +QVK+P
Sbjct: 277 IC----DTSNFSDYIRGGIVSQVKVP 298

[22][TOP]
>UniRef100_Q02053 Ubiquitin-like modifier-activating enzyme 1 n=2 Tax=Mus musculus
           RepID=UBA1_MOUSE
          Length = 1058

 Score =  126 bits (317), Expect = 7e-28
 Identities = 67/148 (45%), Positives = 90/148 (60%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           + + VVVL N  L  Q  V   C    +K +     G+FG +F DFG + V++D NGEQP
Sbjct: 157 SSFQVVVLTNSPLEAQLRVGEFCHSRGIKLVVADTRGLFGQLFCDFGEEMVLTDSNGEQP 216

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
            S M+S +T ++    VV CLDE RH FETGD V+F+EVQG   LN  +  EIKVLGPYT
Sbjct: 217 LSAMVSMVTKDNPG--VVTCLDEARHGFETGDFVSFSEVQGMIQLNGCQPMEIKVLGPYT 274

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F++     + +    Y+RGG  +QVK+P
Sbjct: 275 FSIC----DTSNFSDYIRGGIVSQVKVP 298

[23][TOP]
>UniRef100_UPI00005A5D34 PREDICTED: similar to ubiquitin-activating enzyme E1 n=1 Tax=Canis
           lupus familiaris RepID=UPI00005A5D34
          Length = 1015

 Score =  125 bits (315), Expect = 1e-27
 Identities = 65/146 (44%), Positives = 89/146 (60%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL N  L  Q  V   C    +K +     G+FG +F DFG + +++D NGEQP S
Sbjct: 159 FQVVVLTNTPLEDQLRVGEFCHSRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLS 218

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            M+S +T +     VV CLDE RH FE+GD+V+F+EVQG   LN  +  EIKVLGPYTF+
Sbjct: 219 AMVSMVTKDSPG--VVTCLDEARHGFESGDYVSFSEVQGMVELNGSQPMEIKVLGPYTFS 276

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     + +    Y+RGG  +QVK+P
Sbjct: 277 IC----DTSNFSDYIRGGIVSQVKVP 298

[24][TOP]
>UniRef100_UPI0000EB49FC Ubiquitin-activating enzyme E1 (A1S9 protein). n=1 Tax=Canis lupus
           familiaris RepID=UPI0000EB49FC
          Length = 1023

 Score =  125 bits (315), Expect = 1e-27
 Identities = 65/146 (44%), Positives = 89/146 (60%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL N  L  Q  V   C    +K +     G+FG +F DFG + +++D NGEQP S
Sbjct: 159 FQVVVLTNTPLEDQLRVGEFCHSRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLS 218

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            M+S +T +     VV CLDE RH FE+GD+V+F+EVQG   LN  +  EIKVLGPYTF+
Sbjct: 219 AMVSMVTKDSPG--VVTCLDEARHGFESGDYVSFSEVQGMVELNGSQPMEIKVLGPYTFS 276

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     + +    Y+RGG  +QVK+P
Sbjct: 277 IC----DTSNFSDYIRGGIVSQVKVP 298

[25][TOP]
>UniRef100_Q7RWR0 Ubiquitin-activating enzyme E1 n=1 Tax=Neurospora crassa
           RepID=Q7RWR0_NEUCR
          Length = 1038

 Score =  125 bits (315), Expect = 1e-27
 Identities = 67/147 (45%), Positives = 92/147 (62%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           KY VVVL NQ    QT+V   C    + F++V  +G+FG IF DFG  F V D NGE P 
Sbjct: 142 KYQVVVLTNQHTDLQTIVGEYCHSKGIYFIAVNTHGLFGGIFCDFGDNFTVMDTNGENPV 201

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           + +++ I  E+G   +V+ LDE RH  E GD+VTF+EV+G  GLN  + R++ V GPYTF
Sbjct: 202 NGIVAGID-EEG---LVSALDETRHGLEDGDYVTFSEVEGMEGLNGCEPRKVTVKGPYTF 257

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +V+ +G Y +GG   QVKMP
Sbjct: 258 SI----GDVSGLGQYKKGGLYQQVKMP 280

[26][TOP]
>UniRef100_B3RWM5 Ubiquitin-activating enzyme E1 n=1 Tax=Trichoplax adhaerens
           RepID=B3RWM5_TRIAD
          Length = 1016

 Score =  125 bits (314), Expect = 2e-27
 Identities = 65/146 (44%), Positives = 89/146 (60%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + V++LV  SL+ Q  +     E+ + F+     G+FG +F DFG +F V D NGE+P S
Sbjct: 118 FKVIILVQASLSQQLKIGEFAHESSIAFLVADTRGLFGQVFCDFGAQFQVLDTNGERPIS 177

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            ++S+IT +   + VV C DEQRH  E GD+VTF E++G   LNDGK R+IK LGPYTF+
Sbjct: 178 CLVSSITKDS--EGVVTCADEQRHGLEDGDYVTFKEIRGMVELNDGKPRKIKTLGPYTFS 235

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     +      Y R G  TQVKMP
Sbjct: 236 I----GDTKNYSNYEREGVVTQVKMP 257

[27][TOP]
>UniRef100_Q5U300 Ubiquitin-like modifier-activating enzyme 1 n=1 Tax=Rattus
           norvegicus RepID=UBA1_RAT
          Length = 1058

 Score =  125 bits (314), Expect = 2e-27
 Identities = 67/146 (45%), Positives = 89/146 (60%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL N  L  Q  V   C    +K +     G+FG +F DFG + V++D NGEQP S
Sbjct: 159 FQVVVLTNSPLEEQLRVGEFCHSRGIKLVVADTRGLFGQLFCDFGEEMVLTDSNGEQPLS 218

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            M+S +T ++    VV CLDE RH FETGD V+F+EVQG   LN  +  EIKVLGPYTF+
Sbjct: 219 AMVSMVTKDNPG--VVTCLDEARHGFETGDFVSFSEVQGMVQLNGCQPIEIKVLGPYTFS 276

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     + +    Y+RGG  +QVK+P
Sbjct: 277 IC----DTSNFSDYIRGGIVSQVKVP 298

[28][TOP]
>UniRef100_UPI0000D9F3E5 PREDICTED: similar to ubiquitin-activating enzyme E1 isoform 3 n=1
           Tax=Macaca mulatta RepID=UPI0000D9F3E5
          Length = 1058

 Score =  125 bits (313), Expect = 2e-27
 Identities = 65/146 (44%), Positives = 89/146 (60%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL N  L  Q  V   C    +K +     G+FG +F DFG + +++D NGEQP S
Sbjct: 159 FQVVVLTNTPLEDQLRVGEFCHSRGIKLVVADTRGLFGQLFCDFGKEMILTDSNGEQPLS 218

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            M+S +T ++    VV CLDE RH FE+GD V+F+EVQG   LN  +  EIKVLGPYTF+
Sbjct: 219 AMVSMVTKDNPG--VVTCLDEARHGFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFS 276

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     + +    Y+RGG  +QVK+P
Sbjct: 277 IC----DTSNFSDYIRGGIVSQVKVP 298

[29][TOP]
>UniRef100_P22314 Ubiquitin-like modifier-activating enzyme 1 n=1 Tax=Homo sapiens
           RepID=UBA1_HUMAN
          Length = 1058

 Score =  125 bits (313), Expect = 2e-27
 Identities = 65/146 (44%), Positives = 89/146 (60%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL N  L  Q  V   C    +K +     G+FG +F DFG + +++D NGEQP S
Sbjct: 159 FQVVVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLS 218

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            M+S +T ++    VV CLDE RH FE+GD V+F+EVQG   LN  +  EIKVLGPYTF+
Sbjct: 219 AMVSMVTKDNPG--VVTCLDEARHGFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFS 276

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     + +    Y+RGG  +QVK+P
Sbjct: 277 IC----DTSNFSDYIRGGIVSQVKVP 298

[30][TOP]
>UniRef100_UPI00005C03A6 Ubiquitin activating enzyme 1 n=1 Tax=Bos taurus
           RepID=UPI00005C03A6
          Length = 1059

 Score =  124 bits (312), Expect = 3e-27
 Identities = 65/146 (44%), Positives = 89/146 (60%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL N  L  Q  V   C    +K +     G+FG +F DFG + +++D NGEQP S
Sbjct: 159 FQVVVLTNSPLEDQLRVGEFCHSHGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLS 218

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            M+S +T ++    VV CLDE RH FE+GD V+F+EVQG   LN  +  EIKVLGPYTF+
Sbjct: 219 AMVSMVTKDNPG--VVTCLDEARHGFESGDFVSFSEVQGMIELNGSQPMEIKVLGPYTFS 276

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     + +    Y+RGG  +QVK+P
Sbjct: 277 IC----DTSNFSDYIRGGIVSQVKVP 298

[31][TOP]
>UniRef100_A3KMV5 Ubiquitin-like modifier-activating enzyme 1 n=1 Tax=Bos taurus
           RepID=UBA1_BOVIN
          Length = 1058

 Score =  124 bits (312), Expect = 3e-27
 Identities = 65/146 (44%), Positives = 89/146 (60%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL N  L  Q  V   C    +K +     G+FG +F DFG + +++D NGEQP S
Sbjct: 159 FQVVVLTNSPLEDQLRVGEFCHSHGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLS 218

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            M+S +T ++    VV CLDE RH FE+GD V+F+EVQG   LN  +  EIKVLGPYTF+
Sbjct: 219 AMVSMVTKDNPG--VVTCLDEARHGFESGDFVSFSEVQGMIELNGSQPMEIKVLGPYTFS 276

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     + +    Y+RGG  +QVK+P
Sbjct: 277 IC----DTSNFSDYIRGGIVSQVKVP 298

[32][TOP]
>UniRef100_UPI0001797D66 PREDICTED: ubiquitin-like modifier activating enzyme 1 n=1
           Tax=Equus caballus RepID=UPI0001797D66
          Length = 1058

 Score =  124 bits (311), Expect = 4e-27
 Identities = 65/146 (44%), Positives = 88/146 (60%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL N  L  Q  V   C    +K +     G+FG +F DFG + +++D NGEQP S
Sbjct: 159 FQVVVLTNTPLEDQLRVGEFCHSRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLS 218

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            M+S +T +     VV CLDE RH FE+GD V+F+EVQG   LN  +  EIKVLGPYTF+
Sbjct: 219 AMVSMVTKDSPG--VVTCLDEARHGFESGDFVSFSEVQGMIELNGSQPMEIKVLGPYTFS 276

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     + +    Y+RGG  +QVK+P
Sbjct: 277 IC----DTSNFSDYIRGGIVSQVKVP 298

[33][TOP]
>UniRef100_UPI0000E25F6A PREDICTED: ubiquitin-activating enzyme E1 n=1 Tax=Pan troglodytes
           RepID=UPI0000E25F6A
          Length = 603

 Score =  124 bits (311), Expect = 4e-27
 Identities = 65/144 (45%), Positives = 88/144 (61%)
 Frame = +2

Query: 77  VVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRSVM 256
           VVVL N  L  Q  V   C    +K +     G+FG +F DFG + +++D NGEQP S M
Sbjct: 66  VVVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAM 125

Query: 257 ISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFALV 436
           +S +T ++    VV CLDE RH FE+GD V+F+EVQG   LN  +  EIKVLGPYTF++ 
Sbjct: 126 VSMVTKDNPG--VVTCLDEARHGFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFSIC 183

Query: 437 GCREEVAAMGAYVRGGYATQVKMP 508
               + +    Y+RGG  +QVK+P
Sbjct: 184 ----DTSNFSDYIRGGIVSQVKVP 203

[34][TOP]
>UniRef100_C5WNH5 Ubiquitin-activating enzyme E1 n=1 Tax=Sorghum bicolor
           RepID=C5WNH5_SORBI
          Length = 994

 Score =  124 bits (311), Expect = 4e-27
 Identities = 65/150 (43%), Positives = 93/150 (62%), Gaps = 4/150 (2%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGE 238
           +K+ VVV  + SL      D  CR  +  + F+     G+FGS+F DFGP+F V DV+GE
Sbjct: 89  SKFQVVVFTDISLDKAFEFDDYCRNHQPPISFIKTEVCGLFGSVFCDFGPEFTVLDVDGE 148

Query: 239 QPRSVMISAITLEDGDD--VVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVL 412
            PR+ +I++IT+    D   +V+C+D++R DF+ GD V F+EVQG T LNDGK R +   
Sbjct: 149 DPRTGIIASITISSDSDNHTIVSCVDDERLDFQDGDLVVFSEVQGMTELNDGKPRTVMCT 208

Query: 413 GPYTFALVGCREEVAAMGAYVRGGYATQVK 502
           GP++F    C E+ +  G Y +GG  TQVK
Sbjct: 209 GPFSF----CIEDTSNFGTYTKGGIVTQVK 234

[35][TOP]
>UniRef100_Q1EAX1 Ubiquitin-activating enzyme E1 n=1 Tax=Coccidioides immitis
           RepID=Q1EAX1_COCIM
          Length = 1033

 Score =  124 bits (311), Expect = 4e-27
 Identities = 65/147 (44%), Positives = 90/147 (61%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           KY +VVL N SL  Q V+   C +  +  +    +G+FG IF DFG  F V D  GE+P 
Sbjct: 133 KYQIVVLTNTSLKDQEVIAEYCHQNGIYVLITDTFGLFGYIFTDFGKSFAVGDTTGEEPL 192

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S +++ I  E+G   +V+ LDE RH  E GD+VTFTE++G  GLN+   R++ V GPYTF
Sbjct: 193 SGIVAGID-EEG---LVSALDETRHGLEDGDYVTFTEIKGMEGLNNADPRKVTVKGPYTF 248

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +V+ +G Y  GG  TQVKMP
Sbjct: 249 SI----GDVSGLGTYESGGLYTQVKMP 271

[36][TOP]
>UniRef100_C5PEK5 Ubiquitin-activating enzyme E1 n=1 Tax=Coccidioides posadasii C735
           delta SOWgp RepID=C5PEK5_COCP7
          Length = 1028

 Score =  124 bits (311), Expect = 4e-27
 Identities = 65/147 (44%), Positives = 90/147 (61%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           KY +VVL N SL  Q V+   C +  +  +    +G+FG IF DFG  F V D  GE+P 
Sbjct: 128 KYQIVVLTNTSLKDQEVIAEYCHQNGIYVLITDTFGLFGYIFTDFGQSFAVGDTTGEEPL 187

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S +++ I  E+G   +V+ LDE RH  E GD+VTFTE++G  GLN+   R++ V GPYTF
Sbjct: 188 SGIVAGID-EEG---LVSALDETRHGLEDGDYVTFTEIKGMEGLNNADPRKVTVKGPYTF 243

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +V+ +G Y  GG  TQVKMP
Sbjct: 244 SI----GDVSGLGTYESGGLYTQVKMP 266

[37][TOP]
>UniRef100_UPI0000D57770 PREDICTED: similar to ubiquitin-activating enzyme E1 n=1
           Tax=Tribolium castaneum RepID=UPI0000D57770
          Length = 1041

 Score =  122 bits (307), Expect = 1e-26
 Identities = 66/147 (44%), Positives = 87/147 (59%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           K+ VVVL N  LA Q  +      +++  +     G+F  +F DFG  F V D NGE P 
Sbjct: 150 KFRVVVLTNSCLAEQMQISEITHASNIALIVADTRGLFAQVFCDFGDAFTVVDTNGESPV 209

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S MI+ I+ +   + +V C+D+ RH  E GDHVTF+EVQG T LN+ K  +IKVLGPYTF
Sbjct: 210 SAMIADISTDK--EGIVTCIDDTRHGMEDGDHVTFSEVQGMTELNNCKPIKIKVLGPYTF 267

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +      Y RGG ATQVKMP
Sbjct: 268 SI----GDTTNFSKYERGGIATQVKMP 290

[38][TOP]
>UniRef100_A4RKR7 Ubiquitin-activating enzyme E1 n=1 Tax=Magnaporthe grisea
           RepID=A4RKR7_MAGGR
          Length = 1037

 Score =  122 bits (307), Expect = 1e-26
 Identities = 70/160 (43%), Positives = 97/160 (60%)
 Frame = +2

Query: 29  AASVADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGP 208
           +AS+ D ++ +  KY VVVL N  L +Q  V   C    + F++   +G+FG++F DFG 
Sbjct: 129 SASLTDDLSQLD-KYQVVVLTNAPLVSQKAVGDYCHSKGIYFIAADTFGLFGALFCDFGE 187

Query: 209 KFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDG 388
           KF V D  GE P + M++ I  E+G   +V   D+ RH  E GD+VTFTEVQG  GLN  
Sbjct: 188 KFTVIDSTGENPLNGMVNGID-EEG---LVTTSDDARHGLEDGDYVTFTEVQGMEGLNGC 243

Query: 389 KSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           + R+I V GPYTF++     +V+ +G Y RGG   QVKMP
Sbjct: 244 QPRKITVKGPYTFSI----GDVSGLGTYQRGGLYQQVKMP 279

[39][TOP]
>UniRef100_C4JDQ3 Ubiquitin-activating enzyme E1 n=1 Tax=Uncinocarpus reesii 1704
           RepID=C4JDQ3_UNCRE
          Length = 1028

 Score =  121 bits (303), Expect = 3e-26
 Identities = 63/147 (42%), Positives = 89/147 (60%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           KY +VVL   SL  Q ++   C +  +  +    +G+FG IF DFG  F V D  GE+P 
Sbjct: 128 KYQIVVLTTTSLKDQEIIAEYCHQNGIYVLITDTFGLFGYIFTDFGKNFTVGDTTGEEPV 187

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S +++ I  E+G   +V+ LDE RH  E GD+VTFTE++G  GLN+   R++ V GPYTF
Sbjct: 188 SGIVAGID-EEG---LVSALDETRHGLEDGDYVTFTEIKGMEGLNNADPRKVTVKGPYTF 243

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +V+ +G Y  GG  TQVKMP
Sbjct: 244 SI----GDVSGLGTYQSGGLFTQVKMP 266

[40][TOP]
>UniRef100_Q4P125 Ubiquitin-activating enzyme E1 n=1 Tax=Ustilago maydis
           RepID=Q4P125_USTMA
          Length = 1023

 Score =  120 bits (302), Expect = 4e-26
 Identities = 64/150 (42%), Positives = 91/150 (60%)
 Frame = +2

Query: 59  VAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGE 238
           + +++ VVV+ +   A Q  ++     +   F+S    G+FGS+F DFGPKF+ +D  GE
Sbjct: 124 ILSRFQVVVMSDALYAEQLRINDMTHASSTHFISAEVRGLFGSVFTDFGPKFLCNDPTGE 183

Query: 239 QPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGP 418
           QP S MI +I  ED ++ +V  LDE RH  E GD+V+FTEVQG   LND + R++ V GP
Sbjct: 184 QPLSGMIVSIASED-EEGLVTTLDETRHGLEDGDYVSFTEVQGMDALNDSQPRKVTVKGP 242

Query: 419 YTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           YTF +   +     +G Y +GG   QVKMP
Sbjct: 243 YTFTIGSTK----GLGQYKQGGIFKQVKMP 268

[41][TOP]
>UniRef100_UPI0001553A88 PREDICTED: similar to ubiquitin activating enzyme E1 n=1 Tax=Mus
           musculus RepID=UPI0001553A88
          Length = 1117

 Score =  120 bits (301), Expect = 5e-26
 Identities = 63/146 (43%), Positives = 89/146 (60%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL N  L  Q  V   C    +K +     G+ G +F DFG + +++D NGEQP S
Sbjct: 219 FQVVVLTNTPLEYQLQVGEFCHSHGIKLVVADTRGLVGQLFCDFGEEMILTDSNGEQPLS 278

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            M+S IT E+    +V CL++ RH FE+GD ++FTEVQG + LN     EIKVLGPYTF+
Sbjct: 279 AMVSMITKENPG--IVTCLEDSRHGFESGDFISFTEVQGMSELNGIGPIEIKVLGPYTFS 336

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     + ++   Y+RGG  +QVK+P
Sbjct: 337 IC----DTSSFSEYIRGGIVSQVKVP 358

[42][TOP]
>UniRef100_P31254 Ubiquitin-like modifier-activating enzyme 1 Y n=1 Tax=Mus musculus
           RepID=UBA1Y_MOUSE
          Length = 1058

 Score =  120 bits (301), Expect = 5e-26
 Identities = 63/146 (43%), Positives = 89/146 (60%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL N  L  Q  V   C    +K +     G+ G +F DFG + +++D NGEQP S
Sbjct: 158 FQVVVLTNTPLEYQLQVGEFCHSHGIKLVVADTRGLVGQLFCDFGEEMILTDSNGEQPLS 217

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            M+S IT E+    +V CL++ RH FE+GD ++FTEVQG + LN     EIKVLGPYTF+
Sbjct: 218 AMVSMITKENPG--IVTCLEDSRHGFESGDFISFTEVQGMSELNGIGPIEIKVLGPYTFS 275

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     + ++   Y+RGG  +QVK+P
Sbjct: 276 IC----DTSSFSEYIRGGIVSQVKVP 297

[43][TOP]
>UniRef100_B8MQ48 Ubiquitin-activating enzyme E1 n=1 Tax=Talaromyces stipitatus ATCC
           10500 RepID=B8MQ48_TALSN
          Length = 1030

 Score =  119 bits (299), Expect = 9e-26
 Identities = 63/147 (42%), Positives = 86/147 (58%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           ++ VVVL N SL  Q  +   C +  +  +    +G+FG IFNDFG  F V D  GE P 
Sbjct: 134 RFQVVVLTNTSLKDQLTIADYCHQNGIYVVITDTFGLFGYIFNDFGKNFTVGDATGEDP- 192

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
              +S I  +  +  +V+ LDE RH  E GD+VTFTEV+G  GLN+   R++ V GPYTF
Sbjct: 193 ---VSGIVADIDETGLVSALDETRHGLEDGDYVTFTEVKGMEGLNNNDPRKVTVKGPYTF 249

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +V+ +G Y  GG  TQVKMP
Sbjct: 250 SI----GDVSGLGKYEGGGLYTQVKMP 272

[44][TOP]
>UniRef100_UPI000186E275 ubiquitin-activating enzyme E1, putative n=1 Tax=Pediculus humanus
           corporis RepID=UPI000186E275
          Length = 920

 Score =  119 bits (298), Expect = 1e-25
 Identities = 64/146 (43%), Positives = 86/146 (58%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL N SL  Q  +       D+  +     G+F  +F DFG  F V D NGE P S
Sbjct: 32  FQVVVLTNTSLENQERISEITHNNDIALIIADTRGLFSQLFCDFGNNFTVYDTNGENPLS 91

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            MI+ I+ +   + VV CL+E RH FE GD+VTFTE++G   LND K  +IKVLGPYTF+
Sbjct: 92  AMIADISHDS--EGVVTCLEENRHGFEDGDYVTFTEIRGMEELNDCKPIKIKVLGPYTFS 149

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     + +    Y++GG  +QVKMP
Sbjct: 150 I----GDTSKYSKYIQGGLVSQVKMP 171

[45][TOP]
>UniRef100_C1MHU2 Ubiquitin-activating enzyme E1 n=1 Tax=Micromonas pusilla CCMP1545
           RepID=C1MHU2_9CHLO
          Length = 1016

 Score =  119 bits (298), Expect = 1e-25
 Identities = 67/162 (41%), Positives = 99/162 (61%), Gaps = 1/162 (0%)
 Frame = +2

Query: 20  ADAAASVADAVA-AVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFN 196
           A A   VAD ++ A+ AK+ VVV  +  L   T +DA C +  + F+     GVFGS+F 
Sbjct: 98  AVAVTVVADEISDALCAKHQVVVCTDVPLERATAIDAFCHDNGIAFVRGDVRGVFGSLFC 157

Query: 197 DFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATG 376
           DFGP F V+D +GE+P + ++++++ E     +V C+D+ R + + G  V FTEV+G T 
Sbjct: 158 DFGPAFHVADTDGEEPHTCIVASVSNE--ATPMVTCVDDDRVELQDGQSVIFTEVRGMTE 215

Query: 377 LNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVK 502
           LNDGK R+IK +  ++F L    E+  + GAY  GG ATQVK
Sbjct: 216 LNDGKPRKIKNVKAHSFQL---EEDTTSYGAYTGGGIATQVK 254

[46][TOP]
>UniRef100_Q1WF17 Ubiquitin-activating enzyme E1 n=1 Tax=Felis catus
           RepID=Q1WF17_FELCA
          Length = 1057

 Score =  119 bits (298), Expect = 1e-25
 Identities = 65/146 (44%), Positives = 86/146 (58%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL N  L  Q  V   C    +K +     G+FG +F DFG + ++SD +GEQP S
Sbjct: 159 FQVVVLTNAPLEDQLQVGEFCHSHGIKLVVADTRGLFGQLFCDFGEEMILSDSSGEQPLS 218

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            M+S +T +     VV CLDE RH FE+GD V+FTEVQG   LN     EIKVLGPYTF+
Sbjct: 219 AMVSMVTKDCPG--VVTCLDEARHGFESGDFVSFTEVQGMNELNGTCPIEIKVLGPYTFS 276

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     + +    Y++GG   QVK+P
Sbjct: 277 IC----DTSNFSEYIQGGIVRQVKVP 298

[47][TOP]
>UniRef100_UPI0001792C84 PREDICTED: similar to ubiquitin-activating enzyme E1 n=1
           Tax=Acyrthosiphon pisum RepID=UPI0001792C84
          Length = 1045

 Score =  119 bits (297), Expect = 2e-25
 Identities = 63/147 (42%), Positives = 88/147 (59%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           ++ VVVL   +L  Q  +     + ++  +     GVF  +F DFG  F V D  GE P 
Sbjct: 156 QFKVVVLTETTLDEQLRISEITHQNNIALIVGDTRGVFAQVFCDFGEDFSVIDSTGENPI 215

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           SVM++ +T E+    VV C+DE RH FE GD+VTF EVQG T +N  K ++I VLGPYTF
Sbjct: 216 SVMVAGVTKEEQG--VVTCMDESRHGFEDGDYVTFQEVQGMTEINGCKPKKITVLGPYTF 273

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +  +   Y++GG+ATQVKMP
Sbjct: 274 SI----GDTTSYSDYIKGGFATQVKMP 296

[48][TOP]
>UniRef100_UPI000187EAAA hypothetical protein MPER_11816 n=1 Tax=Moniliophthora perniciosa
           FA553 RepID=UPI000187EAAA
          Length = 716

 Score =  118 bits (296), Expect = 2e-25
 Identities = 66/143 (46%), Positives = 85/143 (59%)
 Frame = +2

Query: 80  VVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRSVMI 259
           +VL   S + Q  ++    E  V F+S    G+FGS+FNDFGPKF   D  GE P S M+
Sbjct: 92  IVLCEASYSKQLELNDWTHENGVHFISTETRGLFGSVFNDFGPKFTCVDPTGENPLSGMV 151

Query: 260 SAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFALVG 439
            ++T +   D +V CLDE RH  E GD VTF+EVQG T LN  + R+I V GPYTF +  
Sbjct: 152 VSVTKDS--DGLVTCLDETRHGLEDGDFVTFSEVQGMTELNGCEPRKISVKGPYTFTI-- 207

Query: 440 CREEVAAMGAYVRGGYATQVKMP 508
              + + +G Y  GG  TQVKMP
Sbjct: 208 --GDTSNLGDYRTGGIFTQVKMP 228

[49][TOP]
>UniRef100_C9S7B8 Putative uncharacterized protein n=1 Tax=Verticillium albo-atrum
           VaMs.102 RepID=C9S7B8_9PEZI
          Length = 1037

 Score =  118 bits (296), Expect = 2e-25
 Identities = 68/147 (46%), Positives = 88/147 (59%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           KY VVVL +  L  Q ++   C    +  ++   +G+FGSIF DFG KF V D  GE P 
Sbjct: 138 KYQVVVLTSLPLKLQGIIGDYCHTKGIYVVAADTFGLFGSIFCDFGEKFTVIDPTGETPL 197

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S +I+ I  E+G   +V+ LDE RH  E GD+VTFTEV+G  GLN    R+I V GPYTF
Sbjct: 198 SGIIAGID-EEG---LVSALDETRHGLEDGDYVTFTEVEGMEGLNGCAPRKITVKGPYTF 253

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +V  +G Y RGG   QVKMP
Sbjct: 254 SI----GDVTGLGQYRRGGLYQQVKMP 276

[50][TOP]
>UniRef100_A1C7R3 Ubiquitin-activating enzyme E1 n=1 Tax=Aspergillus clavatus
           RepID=A1C7R3_ASPCL
          Length = 1045

 Score =  118 bits (296), Expect = 2e-25
 Identities = 62/147 (42%), Positives = 84/147 (57%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           +Y  VVL +  L  Q  +   C +  +       +G+FG IFNDFG  F V D  GE+P 
Sbjct: 146 RYQAVVLTSTPLKEQIAIADFCHKNGIYLTITDTFGLFGYIFNDFGKNFTVGDATGEEP- 204

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
              +S I  +  +D +V+ LDE RH  E GD VTFTE++G  GLN+   R+I V GPYTF
Sbjct: 205 ---VSGIVADIAEDGLVSALDETRHGLEDGDFVTFTEIKGMEGLNNSDPRKITVKGPYTF 261

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +V+ +G Y  GG  TQVKMP
Sbjct: 262 SI----GDVSGLGTYQSGGIFTQVKMP 284

[51][TOP]
>UniRef100_UPI000192531B PREDICTED: similar to predicted protein n=1 Tax=Hydra
           magnipapillata RepID=UPI000192531B
          Length = 1042

 Score =  118 bits (295), Expect = 3e-25
 Identities = 66/148 (44%), Positives = 90/148 (60%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           +K+  VVL N SL+ Q  +       + K +     G+FG +F DFG  F+V+D NGEQ 
Sbjct: 158 SKFQCVVLTNSSLSEQFQISDFIHRNNQKLIIADTKGLFGVLFCDFGNNFIVTDNNGEQV 217

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
            S MI++IT +   + VV CL+E RH FE GD+VTFTEV+G T LN     +IK+LGPYT
Sbjct: 218 ISNMIASITKDS--EGVVTCLEETRHGFEDGDYVTFTEVEGMTELNGCVPLKIKILGPYT 275

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F++     +   +  Y RGG  +QVKMP
Sbjct: 276 FSI----GDTTHLSPYERGGIVSQVKMP 299

[52][TOP]
>UniRef100_UPI0000519F81 PREDICTED: similar to Ubiquitin activating enzyme 1 CG1782-PA
           isoform 1 n=1 Tax=Apis mellifera RepID=UPI0000519F81
          Length = 1049

 Score =  118 bits (295), Expect = 3e-25
 Identities = 63/147 (42%), Positives = 87/147 (59%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           K+ VVVL   SL  Q  +       ++  +     G+F  +F DFG KF + D+NGE P 
Sbjct: 157 KFKVVVLTETSLKEQLRISEITHANNIALIIADTRGLFSQVFCDFGEKFTIVDINGEPPV 216

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S M+++I+ +   + VV CLD+ RH  E GD+VTF+EVQG T LN     +IKVLGPYTF
Sbjct: 217 SAMVASISQDT--EGVVTCLDDTRHGMEDGDYVTFSEVQGMTELNGCDPIKIKVLGPYTF 274

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     + +    Y+RGG  TQVKMP
Sbjct: 275 SI----GDTSKYSEYIRGGIVTQVKMP 297

[53][TOP]
>UniRef100_C9S516 Ubiquitin activating enzyme E1 (Fragment) n=1 Tax=Saimiri sciureus
           RepID=C9S516_SAISC
          Length = 924

 Score =  118 bits (295), Expect = 3e-25
 Identities = 64/145 (44%), Positives = 86/145 (59%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL N  L +Q  V   C    +K +     G+FG +F DFG   ++ D NGEQP S
Sbjct: 25  FQVVVLTNTPLESQLQVGEICHSHGIKLVVADTRGLFGQLFCDFGKDMILRDSNGEQPLS 84

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            M+S IT +     VV CLDE +H FE+GD V+F EVQG + LND    EIKVLGPYTF+
Sbjct: 85  AMVSMITKDSPG--VVTCLDEAQHGFESGDFVSFREVQGMSELNDIHPIEIKVLGPYTFS 142

Query: 431 LVGCREEVAAMGAYVRGGYATQVKM 505
           +     + ++   Y+ GG  +QVK+
Sbjct: 143 IC----DTSSFSDYIGGGIVSQVKV 163

[54][TOP]
>UniRef100_C5FXT0 Ubiquitin-activating enzyme E1 n=1 Tax=Microsporum canis CBS 113480
           RepID=C5FXT0_NANOT
          Length = 1025

 Score =  118 bits (295), Expect = 3e-25
 Identities = 63/146 (43%), Positives = 89/146 (60%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL + SL  QT +   C E  +  +    +G+FG IF DFG  F V D  GE P S
Sbjct: 129 FQVVVLTSTSLKEQTAIAEYCHENGIYVVVTDTFGLFGYIFTDFGKNFTVGDATGENPLS 188

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            +++ I  E+G   +V+ LD+ RH FE GD+VTF+EV+G   LN+ + R++ V GPYTF+
Sbjct: 189 GIVAGID-EEG---LVSALDDARHGFEDGDYVTFSEVRGMEALNNSEPRKVTVKGPYTFS 244

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     +V+ +G Y  GG  TQVKMP
Sbjct: 245 I----GDVSGLGTYEGGGLYTQVKMP 266

[55][TOP]
>UniRef100_P20973 Ubiquitin-activating enzyme E1 1 n=1 Tax=Triticum aestivum
           RepID=UBE11_WHEAT
          Length = 1051

 Score =  118 bits (295), Expect = 3e-25
 Identities = 64/162 (39%), Positives = 99/162 (61%), Gaps = 2/162 (1%)
 Frame = +2

Query: 29  AASVADAVAAVAAKYTVVVLVNQSLATQTVVDAAC--READVKFMSVGAYGVFGSIFNDF 202
           +A   D      +K+  VV  + SL      D  C  ++  + F+     G+FGS+F DF
Sbjct: 138 SALTGDLTKEHLSKFQAVVFTDISLDKAIEFDDYCHSQQPPIAFIKSEVRGLFGSVFCDF 197

Query: 203 GPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLN 382
           GP+F V DV+GE+P + ++++I+  + +  +V+C+D++R +F+ GD V F+EV G T LN
Sbjct: 198 GPEFTVLDVDGEEPHTGIVASIS--NDNPALVSCVDDERLEFQDGDLVVFSEVHGMTELN 255

Query: 383 DGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           DGK R++K   PY+F L    E+ ++ GAYVRGG  TQVK P
Sbjct: 256 DGKPRKVKNARPYSFFL---EEDTSSFGAYVRGGIVTQVKPP 294

[56][TOP]
>UniRef100_C9WPN5 Ube1y1 (Fragment) n=1 Tax=Rattus norvegicus RepID=C9WPN5_RAT
          Length = 913

 Score =  117 bits (294), Expect = 3e-25
 Identities = 63/145 (43%), Positives = 87/145 (60%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL N  L  Q  V   C    +K +     G+ G +F DFG + +++D NGEQP S
Sbjct: 55  FQVVVLTNTPLEYQLQVGEFCHSHGIKLVVADTRGLVGQLFCDFGEEMILTDANGEQPLS 114

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            M+S IT E+    +V CL+E RH FE+GD V+FTEVQG + LN     EIKVLGPY+F+
Sbjct: 115 AMVSMITKENPG--IVTCLEETRHGFESGDFVSFTEVQGMSELNGIGPMEIKVLGPYSFS 172

Query: 431 LVGCREEVAAMGAYVRGGYATQVKM 505
           +     + ++   Y RGG  +QVK+
Sbjct: 173 IC----DTSSFSEYTRGGIVSQVKV 193

[57][TOP]
>UniRef100_A7LAC4 Ubiquitin-activating enzyme E1 n=1 Tax=Rattus norvegicus
           RepID=A7LAC4_RAT
          Length = 1057

 Score =  117 bits (294), Expect = 3e-25
 Identities = 63/145 (43%), Positives = 87/145 (60%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL N  L  Q  V   C    +K +     G+ G +F DFG + +++D NGEQP S
Sbjct: 158 FQVVVLTNTPLEYQLQVGEFCHSHGIKLVVADTRGLVGQLFCDFGEEMILTDANGEQPLS 217

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            M+S IT E+    +V CL+E RH FE+GD V+FTEVQG + LN     EIKVLGPY+F+
Sbjct: 218 AMVSMITKENPG--IVTCLEETRHGFESGDFVSFTEVQGMSELNGIGPMEIKVLGPYSFS 275

Query: 431 LVGCREEVAAMGAYVRGGYATQVKM 505
           +     + ++   Y RGG  +QVK+
Sbjct: 276 IC----DTSSFSEYTRGGIVSQVKV 296

[58][TOP]
>UniRef100_P31251 Ubiquitin-activating enzyme E1 2 n=1 Tax=Triticum aestivum
           RepID=UBE12_WHEAT
          Length = 1051

 Score =  117 bits (294), Expect = 3e-25
 Identities = 64/162 (39%), Positives = 98/162 (60%), Gaps = 2/162 (1%)
 Frame = +2

Query: 29  AASVADAVAAVAAKYTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDF 202
           +A   D      +K+  VV  + SL      D  C   +  + F+     G+FGS+F DF
Sbjct: 138 SALTGDLTKEHLSKFQAVVFTDISLDKAIEFDDYCHSHQPPIAFIKSEVRGLFGSVFCDF 197

Query: 203 GPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLN 382
           GP+F V DV+GE+P + ++++I+  + +  +V+C+D++R +F+ GD V F+EV G T LN
Sbjct: 198 GPEFTVLDVDGEEPHTGIVASIS--NDNPALVSCVDDERLEFQDGDLVVFSEVHGMTELN 255

Query: 383 DGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           DGK R++K   PY+F L    E+ ++ GAYVRGG  TQVK P
Sbjct: 256 DGKPRKVKNARPYSFFL---EEDTSSFGAYVRGGIVTQVKPP 294

[59][TOP]
>UniRef100_P92974 Ubiquitin-activating enzyme E1 n=1 Tax=Arabidopsis thaliana
           RepID=P92974_ARATH
          Length = 1077

 Score =  117 bits (293), Expect = 4e-25
 Identities = 62/148 (41%), Positives = 95/148 (64%), Gaps = 2/148 (1%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           + VVV V+ S    T +D  C   +  + F+     G+FGS+F DFGP F V DV+GE+P
Sbjct: 179 FQVVVFVDISFEKATEIDDYCHSHQPPIAFIKADVRGLFGSLFCDFGPHFTVLDVDGEEP 238

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
            S +I++++ E+     V+C+D++R +FE G+ V F+EV+G T LNDGK R+IK + P++
Sbjct: 239 HSGIIASVSNENPG--FVSCVDDERLEFEDGNLVVFSEVEGMTELNDGKPRKIKNVKPFS 296

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F L    E+ ++ G Y++GG  TQVK P
Sbjct: 297 FTL---EEDTSSYGQYMKGGIVTQVKQP 321

[60][TOP]
>UniRef100_B6Q8A4 Ubiquitin-activating enzyme E1 n=1 Tax=Penicillium marneffei ATCC
           18224 RepID=B6Q8A4_PENMQ
          Length = 1039

 Score =  117 bits (293), Expect = 4e-25
 Identities = 62/147 (42%), Positives = 84/147 (57%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           ++ VVVL N  L  Q V+   C E  +  +    +G+FG IFNDFG  F V D  GE P 
Sbjct: 143 RFQVVVLTNTPLKDQLVIADYCHENGIYVVVADTFGLFGYIFNDFGKNFTVGDATGEDP- 201

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
              +  I  +  +  +V+ LDE RH  E GD+VTFTEV+G  GLN+   R++ V GPYTF
Sbjct: 202 ---VGGIVADIDETGLVSALDETRHGLEDGDYVTFTEVKGMEGLNNSDPRKVTVKGPYTF 258

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     + + +G Y  GG  TQVKMP
Sbjct: 259 SI----GDASGLGKYEGGGLYTQVKMP 281

[61][TOP]
>UniRef100_B6HJN8 Ubiquitin-activating enzyme E1 n=1 Tax=Penicillium chrysogenum
           Wisconsin 54-1255 RepID=B6HJN8_PENCW
          Length = 1033

 Score =  117 bits (292), Expect = 6e-25
 Identities = 64/147 (43%), Positives = 86/147 (58%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           +Y  VVL    L  Q  +   C +  +       +G+FG IFNDFG  F V D NGE+P 
Sbjct: 134 RYQAVVLTQTPLKEQLAIADFCHKNKIYLTITDTFGLFGYIFNDFGKNFTVGDPNGEEPA 193

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S +++ I  E+G   +V+ LDE RH  E GD VTFTEV+G  GLN+   R++ V GPYTF
Sbjct: 194 SGIVADID-EEG---LVSALDETRHGLEDGDFVTFTEVKGMEGLNNSDPRKVTVKGPYTF 249

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
            +     +V+ +G+Y  GG  TQVKMP
Sbjct: 250 TI----GDVSGLGSYQGGGLFTQVKMP 272

[62][TOP]
>UniRef100_A1DID5 Ubiquitin-activating enzyme E1 n=1 Tax=Neosartorya fischeri NRRL
           181 RepID=A1DID5_NEOFI
          Length = 1028

 Score =  117 bits (292), Expect = 6e-25
 Identities = 63/147 (42%), Positives = 84/147 (57%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           +Y  VVL    L  Q  +   C +  +       +G+FG IFNDFG  F V D  GE+P 
Sbjct: 129 QYQAVVLTTTPLNEQLAIADFCHKNGIYITITDTFGLFGYIFNDFGKNFTVGDATGEEP- 187

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
              +S I  +  +D +V+ LDE RH  E GD+VTFTEV+G  GLN+   R+I V GPYTF
Sbjct: 188 ---VSGIVADIDEDGLVSALDETRHGLEDGDYVTFTEVKGMEGLNNCDPRKITVKGPYTF 244

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +V+ +G Y  GG  TQVKMP
Sbjct: 245 SI----GDVSGLGTYQGGGIFTQVKMP 267

[63][TOP]
>UniRef100_Q0WLI0 Ubiquitin activating enzyme 2 (Fragment) n=1 Tax=Arabidopsis
           thaliana RepID=Q0WLI0_ARATH
          Length = 232

 Score =  116 bits (291), Expect = 8e-25
 Identities = 62/146 (42%), Positives = 94/146 (64%), Gaps = 2/146 (1%)
 Frame = +2

Query: 77  VVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           VVV V+ S    T +D  C   +  + F+     G+FGS+F DFGP F V DV+GE+P S
Sbjct: 3   VVVFVDISFEKATEIDDYCHSHQPPIAFIKADVRGLFGSLFCDFGPHFTVLDVDGEEPHS 62

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            +I++++ E+     V+C+D++R +FE G+ V F+EV+G T LNDGK R+IK + P++F 
Sbjct: 63  GIIASVSNENPG--FVSCVDDERLEFEDGNLVVFSEVEGMTELNDGKPRKIKNVKPFSFT 120

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           L    E+ ++ G Y++GG  TQVK P
Sbjct: 121 L---EEDTSSYGQYMKGGIVTQVKQP 143

[64][TOP]
>UniRef100_Q17N86 Ubiquitin-activating enzyme E1 n=1 Tax=Aedes aegypti
           RepID=Q17N86_AEDAE
          Length = 1102

 Score =  116 bits (291), Expect = 8e-25
 Identities = 67/160 (41%), Positives = 87/160 (54%)
 Frame = +2

Query: 29  AASVADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGP 208
           +A   D       K+ VVVL   S   Q  +       ++  ++    G+F  IF DFG 
Sbjct: 183 SAYTGDLTEEFLCKFRVVVLTLTSPTEQHRIAEITHRNNIALITADTRGLFSQIFCDFGT 242

Query: 209 KFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDG 388
            F V D  G  P S M+++IT  +  D +V CLDE RH FE GD+VTFTEV+G + LN  
Sbjct: 243 DFTVYDPTGANPSSAMVASIT--NDVDSIVTCLDENRHGFEDGDYVTFTEVEGMSELNGC 300

Query: 389 KSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
              +IKVLGPYTF++     +     AYVRGG  TQVKMP
Sbjct: 301 DPIKIKVLGPYTFSI----GDTIKFSAYVRGGIVTQVKMP 336

[65][TOP]
>UniRef100_Q17N85 Ubiquitin-activating enzyme E1 n=1 Tax=Aedes aegypti
           RepID=Q17N85_AEDAE
          Length = 1088

 Score =  116 bits (291), Expect = 8e-25
 Identities = 67/160 (41%), Positives = 87/160 (54%)
 Frame = +2

Query: 29  AASVADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGP 208
           +A   D       K+ VVVL   S   Q  +       ++  ++    G+F  IF DFG 
Sbjct: 183 SAYTGDLTEEFLCKFRVVVLTLTSPTEQHRIAEITHRNNIALITADTRGLFSQIFCDFGT 242

Query: 209 KFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDG 388
            F V D  G  P S M+++IT  +  D +V CLDE RH FE GD+VTFTEV+G + LN  
Sbjct: 243 DFTVYDPTGANPSSAMVASIT--NDVDSIVTCLDENRHGFEDGDYVTFTEVEGMSELNGC 300

Query: 389 KSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
              +IKVLGPYTF++     +     AYVRGG  TQVKMP
Sbjct: 301 DPIKIKVLGPYTFSI----GDTIKFSAYVRGGIVTQVKMP 336

[66][TOP]
>UniRef100_B0XUU0 Ubiquitin-activating enzyme E1 n=2 Tax=Aspergillus fumigatus
           RepID=B0XUU0_ASPFC
          Length = 1028

 Score =  116 bits (291), Expect = 8e-25
 Identities = 63/147 (42%), Positives = 84/147 (57%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           +Y  VVL    L  Q  +   C +  +       +G+FG IFNDFG  F V D  GE+P 
Sbjct: 129 QYQAVVLTATPLKEQLAIADFCHKNGIYITITDTFGLFGYIFNDFGKNFTVGDATGEEP- 187

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
              +S I  +  +D +V+ LDE RH  E GD+VTFTEV+G  GLN+   R+I V GPYTF
Sbjct: 188 ---VSGIVADIDEDGLVSALDETRHGLEDGDYVTFTEVKGMEGLNNCDPRKITVKGPYTF 244

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +V+ +G Y  GG  TQVKMP
Sbjct: 245 SI----GDVSGLGTYQGGGIFTQVKMP 267

[67][TOP]
>UniRef100_A9SFQ4 Ubiquitin-activating enzyme E1 n=1 Tax=Physcomitrella patens subsp.
           patens RepID=A9SFQ4_PHYPA
          Length = 1018

 Score =  116 bits (290), Expect = 1e-24
 Identities = 62/160 (38%), Positives = 96/160 (60%), Gaps = 2/160 (1%)
 Frame = +2

Query: 35  SVADAVAAVAAKYTVVVLVNQSLATQTVVDAAC--READVKFMSVGAYGVFGSIFNDFGP 208
           S  D    + + ++VVV  + +L     +D  C  RE  + F+     GVFGS+F DFGP
Sbjct: 108 STGDITEQLLSAHSVVVFTDITLDKAIEIDEFCHRREPAIAFIKADIRGVFGSVFCDFGP 167

Query: 209 KFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDG 388
            F V DV+GE+P + +I++I+  + +  +V C+D++R + + GD VTF+EV G + LNDG
Sbjct: 168 SFTVVDVDGEEPHTGIIASIS--NDNPALVTCVDDERLELQDGDLVTFSEVHGMSELNDG 225

Query: 389 KSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           + R +K   PY+F L    ++    GAY +GG  TQVK+P
Sbjct: 226 RPRRVKGTRPYSFLL---EDDTTGYGAYEKGGIFTQVKLP 262

[68][TOP]
>UniRef100_Q0CV33 Ubiquitin-activating enzyme E1 n=1 Tax=Aspergillus terreus NIH2624
           RepID=Q0CV33_ASPTN
          Length = 1050

 Score =  116 bits (290), Expect = 1e-24
 Identities = 61/147 (41%), Positives = 83/147 (56%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           +Y  VVL    L  Q  +   C +  +       +G+FG +FNDFG  F V D  GE+P 
Sbjct: 150 RYQAVVLTLTPLKDQLAIADFCHKNGIYVTITDTFGLFGYLFNDFGKNFTVGDATGEEP- 208

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
              +S I  +  +D +V+ LDE RH  E GD VTF+EV+G  GLND   R++ V GPYTF
Sbjct: 209 ---VSGIVADIDEDGLVSALDESRHGLEDGDFVTFSEVKGMEGLNDAAPRKVTVKGPYTF 265

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +V+ +G Y  GG  TQVKMP
Sbjct: 266 SI----GDVSGLGTYKSGGIFTQVKMP 288

[69][TOP]
>UniRef100_B2AZ06 Ubiquitin-activating enzyme E1 (Fragment) n=1 Tax=Podospora
           anserina RepID=B2AZ06_PODAN
          Length = 1032

 Score =  116 bits (290), Expect = 1e-24
 Identities = 65/147 (44%), Positives = 89/147 (60%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           KY VVVL N     + +V   C E  + F++    G+F +IF DFG  F V D +GE P 
Sbjct: 137 KYQVVVLTNTPQHLKVLVGDYCHEKGIYFIAAETAGLFANIFCDFGNNFTVLDSSGENPV 196

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S +++ I  E+G   +V+ LDE RH  E GD+VTFTEV+G  GLN  + R++ V GPYTF
Sbjct: 197 SGIVAGID-EEG---LVSALDETRHGLEDGDYVTFTEVEGMEGLNGAEPRKVTVRGPYTF 252

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +V+ +G Y RGG   QVKMP
Sbjct: 253 SI----GDVSGLGQYKRGGLYQQVKMP 275

[70][TOP]
>UniRef100_UPI000023F674 hypothetical protein FG09689.1 n=1 Tax=Gibberella zeae PH-1
           RepID=UPI000023F674
          Length = 1033

 Score =  115 bits (289), Expect = 1e-24
 Identities = 64/147 (43%), Positives = 87/147 (59%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           KY VVVL N  +  Q  +   C    +  +    +G+FGS+F DFG KF V D  GE P 
Sbjct: 138 KYQVVVLTNAPIHQQKAIADYCHSKGIYVVVADTFGLFGSVFCDFGEKFTVIDPTGETPL 197

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S +++ I  E+G   +V+ LDE RH  E GD+VTF+EV+G   LN  + R+I V GPYTF
Sbjct: 198 SGIVAGID-EEG---MVSALDETRHGLEDGDYVTFSEVEGMEALNGAEPRKITVKGPYTF 253

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +V+ +G Y RGG   QVKMP
Sbjct: 254 SI----GDVSGLGQYKRGGMYQQVKMP 276

[71][TOP]
>UniRef100_Q10MU6 Ubiquitin-activating enzyme E1 n=1 Tax=Oryza sativa Japonica Group
           RepID=Q10MU6_ORYSJ
          Length = 1064

 Score =  115 bits (289), Expect = 1e-24
 Identities = 61/150 (40%), Positives = 94/150 (62%), Gaps = 2/150 (1%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGE 238
           +K+  VV  + SL      D  CR  +  + F+     G+FGS+F DFGPKF V DV+GE
Sbjct: 164 SKFQAVVFTDISLDKAFEFDDYCRNHQPSISFIKAEVCGLFGSVFCDFGPKFTVLDVDGE 223

Query: 239 QPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGP 418
           +P + +I++I+  + +  +++C+D++R +F+ GD V F+EVQG T LNDGK R+I    P
Sbjct: 224 EPHTGIIASIS--NDNPAMISCVDDERLEFQDGDLVVFSEVQGMTELNDGKPRKIINARP 281

Query: 419 YTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           Y+F +   +E+ +  G Y +GG  TQVK P
Sbjct: 282 YSFCI---QEDTSKFGIYAKGGIVTQVKEP 308

[72][TOP]
>UniRef100_B9F7T7 Ubiquitin-activating enzyme E1 n=1 Tax=Oryza sativa Japonica Group
           RepID=B9F7T7_ORYSJ
          Length = 1179

 Score =  115 bits (289), Expect = 1e-24
 Identities = 61/150 (40%), Positives = 94/150 (62%), Gaps = 2/150 (1%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGE 238
           +K+  VV  + SL      D  CR  +  + F+     G+FGS+F DFGPKF V DV+GE
Sbjct: 279 SKFQAVVFTDISLDKAFEFDDYCRNHQPSISFIKAEVCGLFGSVFCDFGPKFTVLDVDGE 338

Query: 239 QPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGP 418
           +P + +I++I+  + +  +++C+D++R +F+ GD V F+EVQG T LNDGK R+I    P
Sbjct: 339 EPHTGIIASIS--NDNPAMISCVDDERLEFQDGDLVVFSEVQGMTELNDGKPRKIINARP 396

Query: 419 YTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           Y+F +   +E+ +  G Y +GG  TQVK P
Sbjct: 397 YSFCI---QEDTSKFGIYAKGGIVTQVKEP 423

[73][TOP]
>UniRef100_A9V503 Ubiquitin-activating enzyme E1 n=1 Tax=Monosiga brevicollis
           RepID=A9V503_MONBE
          Length = 1005

 Score =  115 bits (289), Expect = 1e-24
 Identities = 65/148 (43%), Positives = 84/148 (56%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           AK+ VVVL   +L  Q  V+      +   +     G+FG +F DFGP F V D NGEQP
Sbjct: 115 AKFQVVVLTESTLQEQIRVNKVTHTNNKALIVASTRGLFGQLFCDFGPDFAVVDTNGEQP 174

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
           RS ++ +IT +   + VV   D+ RHD E GD VTF+E+ G   LN  + R IKV GP+T
Sbjct: 175 RSALVVSITKD--KEGVVTVHDDARHDMEDGDFVTFSEIHGMEELNGCEPRPIKVTGPFT 232

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F +     +   M  YVRGG  TQVKMP
Sbjct: 233 FTI----GDTTGMTDYVRGGNVTQVKMP 256

[74][TOP]
>UniRef100_A8NWJ7 Putative uncharacterized protein n=1 Tax=Coprinopsis cinerea
           okayama7#130 RepID=A8NWJ7_COPC7
          Length = 786

 Score =  115 bits (289), Expect = 1e-24
 Identities = 68/146 (46%), Positives = 83/146 (56%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL    L  Q  ++       + F++    G+FGS FNDFG KF   D  GEQP S
Sbjct: 131 FQVVVLCGVPLKKQLEINDWTHANGIPFIAAETRGLFGSAFNDFGSKFTCVDPTGEQPLS 190

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            MI +I  E   D +V CLDE RH  E GD VTFTEVQG T LN  + R++ V GPYTF 
Sbjct: 191 GMIVSIDKEQ--DGLVTCLDETRHGLEDGDFVTFTEVQGMTELNGCEPRKVTVKGPYTFT 248

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     +V+  G Y  GG  TQVKMP
Sbjct: 249 I----GDVSNFGDYKTGGIFTQVKMP 270

[75][TOP]
>UniRef100_Q8RX82 Ubiquitin-activating enzyme E1 n=1 Tax=Arabidopsis thaliana
           RepID=Q8RX82_ARATH
          Length = 1080

 Score =  115 bits (288), Expect = 2e-24
 Identities = 62/148 (41%), Positives = 91/148 (61%), Gaps = 2/148 (1%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           + VVV  + S+      D  C   +  + F+     G+FGS+F DFGP+F V DV+GE+P
Sbjct: 182 FQVVVFSDISMERAIEFDDYCHSHQPPIAFVKADVRGLFGSVFCDFGPEFAVLDVDGEEP 241

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
            + +I++I+ E+     ++C+D++R +FE GD V F+EV+G T LNDGK R+IK   PY+
Sbjct: 242 HTGIIASISNEN--QAFISCVDDERLEFEDGDLVVFSEVEGMTELNDGKPRKIKSTRPYS 299

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F L    E+    G YV+GG  TQVK P
Sbjct: 300 FTL---DEDTTNYGTYVKGGIVTQVKQP 324

[76][TOP]
>UniRef100_P93028 Ubiquitin-activating enzyme E1 n=1 Tax=Arabidopsis thaliana
           RepID=P93028_ARATH
          Length = 1080

 Score =  115 bits (288), Expect = 2e-24
 Identities = 62/148 (41%), Positives = 91/148 (61%), Gaps = 2/148 (1%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           + VVV  + S+      D  C   +  + F+     G+FGS+F DFGP+F V DV+GE+P
Sbjct: 182 FQVVVFSDISMERAIEFDDYCHSHQPPIAFVKADVRGLFGSVFCDFGPEFAVLDVDGEEP 241

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
            + +I++I+ E+     ++C+D++R +FE GD V F+EV+G T LNDGK R+IK   PY+
Sbjct: 242 HTGIIASISNEN--QAFISCVDDERLEFEDGDLVVFSEVEGMTELNDGKPRKIKSTRPYS 299

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F L    E+    G YV+GG  TQVK P
Sbjct: 300 FTL---DEDTTNYGTYVKGGIVTQVKQP 324

[77][TOP]
>UniRef100_A7ESF4 Ubiquitin-activating enzyme E1 n=1 Tax=Sclerotinia sclerotiorum
           1980 UF-70 RepID=A7ESF4_SCLS1
          Length = 1061

 Score =  115 bits (288), Expect = 2e-24
 Identities = 68/168 (40%), Positives = 97/168 (57%)
 Frame = +2

Query: 5   VSLLAADAAASVADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFG 184
           VS+  + ++ S+ D +     +Y VVVL N SL  Q ++     +  +  +    +G+FG
Sbjct: 142 VSVHKSSSSRSLTDDLTQFD-RYQVVVLTNTSLRDQIIIGDYLHKKGIYLVVADTFGLFG 200

Query: 185 SIFNDFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQ 364
           SIF DFG KF V D  GE P S +++ I  E+G   +V+ LDE RH  E GD+VTFTE++
Sbjct: 201 SIFCDFGEKFTVLDPTGEAPVSGIVAGID-EEG---LVSALDETRHGLEDGDYVTFTELE 256

Query: 365 GATGLNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           G   LN    R++ V GPYTF++     +V  +G Y RGG   QVKMP
Sbjct: 257 GLEALNSADPRKVTVKGPYTFSI----GDVTGLGQYQRGGMYHQVKMP 300

[78][TOP]
>UniRef100_A5DLS9 Ubiquitin-activating enzyme E1 n=1 Tax=Pichia guilliermondii
           RepID=A5DLS9_PICGU
          Length = 1015

 Score =  115 bits (288), Expect = 2e-24
 Identities = 67/158 (42%), Positives = 87/158 (55%), Gaps = 1/158 (0%)
 Frame = +2

Query: 38  VADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFV 217
           V D  A+  A +  VV  N +L  Q  ++      D  F+S    G+FG +F DFG KF 
Sbjct: 109 VDDLSASTLASFKCVVCTNTTLEEQIRINEVTHANDTGFISADVRGLFGQLFVDFGEKFT 168

Query: 218 VSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSR 397
           V D  GE+P   ++S I      D  V  LD+ RH  E GD+V F+EVQG   LNDG  R
Sbjct: 169 VVDQTGEEPHQGIVSDIE----KDGTVTMLDDNRHGLEDGDYVKFSEVQGMPNLNDGNPR 224

Query: 398 EIKVLGPYTFAL-VGCREEVAAMGAYVRGGYATQVKMP 508
           +I+VLGPY F + +G  +     G YV+GG  TQVKMP
Sbjct: 225 KIEVLGPYAFRIKLGPND-----GEYVKGGLYTQVKMP 257

[79][TOP]
>UniRef100_A7QKV2 Ubiquitin-activating enzyme E1 n=2 Tax=Vitis vinifera
           RepID=A7QKV2_VITVI
          Length = 991

 Score =  115 bits (287), Expect = 2e-24
 Identities = 62/148 (41%), Positives = 91/148 (61%), Gaps = 2/148 (1%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           +  VV  N S+      D  C   +  + F+     G+FGS+F DFGP+F V DV+GE P
Sbjct: 93  FQAVVFTNISIEKAIEFDDYCHNHQPPISFIKSEVRGLFGSVFCDFGPEFTVFDVDGEDP 152

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
            + +I++I+  + +  +VAC+D++R +F+ GD V F+EVQG T LNDGK R++K   PY+
Sbjct: 153 HTGIIASIS--NDNPALVACVDDERLEFQDGDLVVFSEVQGMTELNDGKPRKVKNARPYS 210

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F+L    E+    GAY +GG  TQVK P
Sbjct: 211 FSL---DEDTTNYGAYEKGGIVTQVKQP 235

[80][TOP]
>UniRef100_Q6C6V1 Ubiquitin-activating enzyme E1 n=1 Tax=Yarrowia lipolytica
           RepID=Q6C6V1_YARLI
          Length = 1015

 Score =  115 bits (287), Expect = 2e-24
 Identities = 67/148 (45%), Positives = 91/148 (61%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           A++ VVVL N SL  Q  V+    + ++ F+S    G+FG+IF DFG  F + D NGE+P
Sbjct: 124 ARFQVVVLTNASLEEQIRVNEITHKQNIGFVSTDTRGLFGNIFVDFGSSFALIDANGEEP 183

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
            S +I+ I  E+G+   VA LDE RH+ E GD+V FTEV+G   +N    R+IKV GPY+
Sbjct: 184 HSGIIAGID-EEGN---VAALDETRHNLEDGDYVKFTEVEG-LDINGDTPRKIKVTGPYS 238

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F +      V  +G Y +GG  TQVKMP
Sbjct: 239 FNI----GSVDGLGTYKKGGLFTQVKMP 262

[81][TOP]
>UniRef100_Q2GZZ6 Ubiquitin-activating enzyme E1 n=1 Tax=Chaetomium globosum
           RepID=Q2GZZ6_CHAGB
          Length = 1030

 Score =  115 bits (287), Expect = 2e-24
 Identities = 63/147 (42%), Positives = 87/147 (59%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           +Y VVVL N     Q  V   C E  + F+    +G+FGS+F DFG  F + D  GE P 
Sbjct: 139 QYQVVVLTNTPQHIQQTVGDYCHEKGIYFIVADTFGLFGSVFCDFGKNFTIIDATGENPL 198

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           + +++ I  E G   +V+ LDE RH  E GD+VTF+EV+G  GLN  + R++ V GPYTF
Sbjct: 199 NGIVAGID-ETG---LVSALDETRHGLEDGDYVTFSEVEGMEGLNGCEPRKVTVRGPYTF 254

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +V+ +G Y RGG   QVKMP
Sbjct: 255 SI----GDVSGLGHYKRGGLYQQVKMP 277

[82][TOP]
>UniRef100_UPI000151BBA9 ubiquitin-activating enzyme E1 1 n=1 Tax=Pichia guilliermondii ATCC
           6260 RepID=UPI000151BBA9
          Length = 1015

 Score =  114 bits (286), Expect = 3e-24
 Identities = 67/158 (42%), Positives = 87/158 (55%), Gaps = 1/158 (0%)
 Frame = +2

Query: 38  VADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFV 217
           V D  A+  A +  VV  N +L  Q  ++      D  F+S    G+FG +F DFG KF 
Sbjct: 109 VDDLSASTLALFKCVVCTNTTLEEQIRINEVTHANDTGFISADVRGLFGQLFVDFGEKFT 168

Query: 218 VSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSR 397
           V D  GE+P   ++S I      D  V  LD+ RH  E GD+V F+EVQG   LNDG  R
Sbjct: 169 VVDQTGEEPHQGIVSDIE----KDGTVTMLDDNRHGLEDGDYVKFSEVQGMPNLNDGNPR 224

Query: 398 EIKVLGPYTFAL-VGCREEVAAMGAYVRGGYATQVKMP 508
           +I+VLGPY F + +G  +     G YV+GG  TQVKMP
Sbjct: 225 KIEVLGPYAFRIKLGPND-----GEYVKGGLYTQVKMP 257

[83][TOP]
>UniRef100_Q55C16 Ubiquitin-like modifier-activating enzyme 1 n=1 Tax=Dictyostelium
           discoideum RepID=UBA1_DICDI
          Length = 1017

 Score =  114 bits (286), Expect = 3e-24
 Identities = 61/147 (41%), Positives = 87/147 (59%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           K+ VVVL NQ LA Q  V+  C    + F+SV   GVFG +FNDFG +F ++D NGE P 
Sbjct: 122 KFNVVVLANQPLALQLKVNEFCHANKIHFISVETRGVFGQLFNDFGEQFTITDTNGENPN 181

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           + MIS+I+ +   + +V  ++EQ+     GD VTF EV G + LND   ++IK + P TF
Sbjct: 182 AYMISSISQD--KEGIVTVVEEQKLQLLDGDLVTFKEVNGMSALNDLPPQKIKTISPLTF 239

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +   +  Y  GGY T+VK P
Sbjct: 240 SI----GDTTNLPPYTSGGYVTEVKQP 262

[84][TOP]
>UniRef100_Q2RBM4 Ubiquitin-activating enzyme E1 n=1 Tax=Oryza sativa Japonica Group
           RepID=Q2RBM4_ORYSJ
          Length = 1048

 Score =  114 bits (284), Expect = 5e-24
 Identities = 60/150 (40%), Positives = 93/150 (62%), Gaps = 2/150 (1%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGE 238
           + +  VV  + SL      D+ C   +  + F+     G+FGS+F DFGP+F V DV+GE
Sbjct: 148 SNFQAVVFTDISLEKAVEFDSYCHNHQPPIAFIKSEIRGLFGSVFCDFGPEFTVLDVDGE 207

Query: 239 QPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGP 418
           +P + ++++I+  + +  +V+C+D++R +F+ GD V F+EV G + LNDGK R+IK   P
Sbjct: 208 EPHTGIVASIS--NDNPALVSCVDDERLEFQDGDLVVFSEVHGMSELNDGKPRKIKNARP 265

Query: 419 YTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           Y+F L    E+  + G YVRGG  TQVK P
Sbjct: 266 YSFTL---EEDTTSYGTYVRGGIVTQVKPP 292

[85][TOP]
>UniRef100_Q2QYU8 Ubiquitin-activating enzyme E1 n=1 Tax=Oryza sativa Japonica Group
           RepID=Q2QYU8_ORYSJ
          Length = 968

 Score =  114 bits (284), Expect = 5e-24
 Identities = 60/150 (40%), Positives = 93/150 (62%), Gaps = 2/150 (1%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGE 238
           + +  VV  + SL      D+ C   +  + F+     G+FGS+F DFGP+F V DV+GE
Sbjct: 149 SNFQAVVFTDISLEKAVEFDSYCHNHQPPIAFIKSEIRGLFGSVFCDFGPEFTVLDVDGE 208

Query: 239 QPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGP 418
           +P + ++++I+  + +  +V+C+D++R +F+ GD V F+EV G + LNDGK R+IK   P
Sbjct: 209 EPHTGIVASIS--NDNPALVSCVDDERLEFQDGDLVVFSEVHGMSELNDGKPRKIKNARP 266

Query: 419 YTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           Y+F L    E+  + G YVRGG  TQVK P
Sbjct: 267 YSFTL---EEDTTSYGTYVRGGIVTQVKPP 293

[86][TOP]
>UniRef100_C5Y2Z7 Ubiquitin-activating enzyme E1 n=1 Tax=Sorghum bicolor
           RepID=C5Y2Z7_SORBI
          Length = 1052

 Score =  114 bits (284), Expect = 5e-24
 Identities = 59/150 (39%), Positives = 92/150 (61%), Gaps = 2/150 (1%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGE 238
           + +  VV  + S+      D  C   +  + F+     G+FGS+F DFGP+F V DV+GE
Sbjct: 152 SNFQAVVFTDISIEKAVEFDDYCHSHQPPIAFIKSEVRGLFGSVFCDFGPEFTVLDVDGE 211

Query: 239 QPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGP 418
           +P + ++++I+  + +  +V+C+D++R +F+ GD V F+EV G T LNDGK R+IK   P
Sbjct: 212 EPHTGIVASIS--NDNPALVSCVDDERLEFQDGDLVVFSEVHGMTELNDGKPRKIKSARP 269

Query: 419 YTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           Y+F L    E+  + G Y+RGG  TQVK P
Sbjct: 270 YSFTL---EEDTTSYGTYIRGGIVTQVKPP 296

[87][TOP]
>UniRef100_B8BIM9 DNA-directed RNA polymerase n=1 Tax=Oryza sativa Indica Group
           RepID=B8BIM9_ORYSI
          Length = 1099

 Score =  114 bits (284), Expect = 5e-24
 Identities = 60/150 (40%), Positives = 93/150 (62%), Gaps = 2/150 (1%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGE 238
           + +  VV  + SL      D+ C   +  + F+     G+FGS+F DFGP+F V DV+GE
Sbjct: 210 SNFQAVVFTDISLEKAVEFDSYCHNHQPPIAFIKSEIRGLFGSVFCDFGPEFTVLDVDGE 269

Query: 239 QPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGP 418
           +P + ++++I+  + +  +V+C+D++R +F+ GD V F+EV G + LNDGK R+IK   P
Sbjct: 270 EPHTGIVASIS--NDNPALVSCVDDERLEFQDGDLVVFSEVHGMSELNDGKPRKIKNARP 327

Query: 419 YTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           Y+F L    E+  + G YVRGG  TQVK P
Sbjct: 328 YSFTL---EEDTTSYGTYVRGGIVTQVKPP 354

[88][TOP]
>UniRef100_B3MCI3 Ubiquitin-activating enzyme E1 n=1 Tax=Drosophila ananassae
           RepID=B3MCI3_DROAN
          Length = 1191

 Score =  113 bits (283), Expect = 6e-24
 Identities = 63/148 (42%), Positives = 86/148 (58%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           +++ VVVL N S   Q  +     E ++  +     G+F  +F DFG  F + D +G QP
Sbjct: 304 SQFRVVVLTNSSSEEQQRIGKFAHENNIALIIAETRGLFAKVFCDFGENFTIYDQDGAQP 363

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
            S MI+++T +     VV CLDE RH F  GD+VTF+EVQG T LN  +  +I VLGPYT
Sbjct: 364 VSTMIASVTHDAQG--VVTCLDETRHGFTDGDYVTFSEVQGMTELNGCQPIKINVLGPYT 421

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F++     + +  G Y  GG ATQVKMP
Sbjct: 422 FSI----GDTSTFGEYKSGGVATQVKMP 445

[89][TOP]
>UniRef100_C7Z6M3 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
           RepID=C7Z6M3_NECH7
          Length = 1035

 Score =  113 bits (283), Expect = 6e-24
 Identities = 62/147 (42%), Positives = 87/147 (59%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           KY +VVL N  +  Q  +   C    +  +    +G+FGSIF DFG KF V D  GE P 
Sbjct: 138 KYQIVVLTNVPIHHQKAIGDYCHNKGIYVVIADTFGLFGSIFCDFGDKFTVIDPTGETPL 197

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S +++ +  E+G   +V+ LDE RH  E GD+VTF+E++G   LN  + R+I V GPYTF
Sbjct: 198 SGIVAGVD-EEG---LVSALDETRHGLEDGDYVTFSEIEGMEALNGCEPRKITVKGPYTF 253

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +V+ +G Y RGG   QVKMP
Sbjct: 254 SI----GDVSGLGQYQRGGMYQQVKMP 276

[90][TOP]
>UniRef100_B4MS69 Ubiquitin-activating enzyme E1 n=1 Tax=Drosophila willistoni
           RepID=B4MS69_DROWI
          Length = 1209

 Score =  113 bits (282), Expect = 8e-24
 Identities = 63/147 (42%), Positives = 83/147 (56%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           K+ V+VL N     Q  +     E  +  +     G+F  IF DFG  F + D +G QP 
Sbjct: 322 KFRVIVLTNSDAEEQQRIGKFAHENGIALIIAETRGLFAKIFCDFGENFTIYDQDGAQPV 381

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S MI+++T  +    VV CLDE RH F  GD+VTF+EVQG   LN  +  +I VLGPYTF
Sbjct: 382 STMIASVT--NDAQGVVTCLDETRHGFNDGDYVTFSEVQGMKELNGCQPIKINVLGPYTF 439

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     + +A G Y  GG ATQVKMP
Sbjct: 440 SI----GDTSAFGVYKSGGVATQVKMP 462

[91][TOP]
>UniRef100_Q75VJ8 Ubiquitin-activating enzyme E1 n=1 Tax=Nicotiana tabacum
           RepID=Q75VJ8_TOBAC
          Length = 1080

 Score =  112 bits (281), Expect = 1e-23
 Identities = 61/150 (40%), Positives = 91/150 (60%), Gaps = 2/150 (1%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGE 238
           + +  VV  + SL      D  C   +  + F+     G+FGS+F DFGP+F V+DV+GE
Sbjct: 180 SNFQAVVFTDISLEKAVEFDDYCHKHQPPIAFIKAEVRGLFGSVFCDFGPEFTVADVDGE 239

Query: 239 QPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGP 418
            P + +I++I+  + +  +V C+D++R +FE GD V F+EV+G T LNDGK R+IK   P
Sbjct: 240 DPHTGIIASIS--NDNPALVGCIDDERLEFEDGDLVIFSEVRGMTELNDGKPRKIKNARP 297

Query: 419 YTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           Y+F +    E+ +   AY RGG  TQVK P
Sbjct: 298 YSFTI---EEDTSNYAAYERGGIVTQVKEP 324

[92][TOP]
>UniRef100_B9GBE8 Ubiquitin-activating enzyme E1 n=1 Tax=Oryza sativa Japonica Group
           RepID=B9GBE8_ORYSJ
          Length = 1064

 Score =  112 bits (281), Expect = 1e-23
 Identities = 60/145 (41%), Positives = 91/145 (62%), Gaps = 2/145 (1%)
 Frame = +2

Query: 80  VVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRSV 253
           VV  + SL      D+ C   +  + F+     G+FGS+F DFGP+F V DV+GE+P + 
Sbjct: 169 VVFTDISLEKAVEFDSYCHNHQPPIAFIKSEIRGLFGSVFCDFGPEFTVLDVDGEEPHTG 228

Query: 254 MISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFAL 433
           ++++I+  + +  +V+C+D++R +F+ GD V F+EV G + LNDGK R+IK   PY+F L
Sbjct: 229 IVASIS--NDNPALVSCVDDERLEFQDGDLVVFSEVHGMSELNDGKPRKIKNARPYSFTL 286

Query: 434 VGCREEVAAMGAYVRGGYATQVKMP 508
               E+  + G YVRGG  TQVK P
Sbjct: 287 ---EEDTTSYGTYVRGGIVTQVKPP 308

[93][TOP]
>UniRef100_B8BNT8 Ubiquitin-activating enzyme E1 n=1 Tax=Oryza sativa Indica Group
           RepID=B8BNT8_ORYSI
          Length = 1063

 Score =  112 bits (281), Expect = 1e-23
 Identities = 60/145 (41%), Positives = 91/145 (62%), Gaps = 2/145 (1%)
 Frame = +2

Query: 80  VVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRSV 253
           VV  + SL      D+ C   +  + F+     G+FGS+F DFGP+F V DV+GE+P + 
Sbjct: 168 VVFTDISLEKAVEFDSYCHNHQPPIAFIKSEIRGLFGSVFCDFGPEFTVLDVDGEEPHTG 227

Query: 254 MISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFAL 433
           ++++I+  + +  +V+C+D++R +F+ GD V F+EV G + LNDGK R+IK   PY+F L
Sbjct: 228 IVASIS--NDNPALVSCVDDERLEFQDGDLVVFSEVHGMSELNDGKPRKIKNARPYSFTL 285

Query: 434 VGCREEVAAMGAYVRGGYATQVKMP 508
               E+  + G YVRGG  TQVK P
Sbjct: 286 ---EEDTTSYGTYVRGGIVTQVKPP 307

[94][TOP]
>UniRef100_B8N6L0 Ubiquitin-activating enzyme E1 n=2 Tax=Aspergillus
           RepID=B8N6L0_ASPFN
          Length = 1034

 Score =  112 bits (280), Expect = 1e-23
 Identities = 59/147 (40%), Positives = 82/147 (55%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           +Y  VVL    L  Q  +   C +  +       +G+FG +FNDFG  F + D  GE+  
Sbjct: 134 RYQAVVLTLTPLKDQLAIADFCHKNGIYLTIADTFGLFGYLFNDFGKNFTIGDATGEE-- 191

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
             ++S I     +D +V+ LDE RH  E GD+VTFTEV+G  GLN+   R++ V GPYTF
Sbjct: 192 --LVSGIVAGIDEDGLVSALDESRHGLEDGDYVTFTEVKGMDGLNNSAPRKVTVKGPYTF 249

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
            +     +V+ +G Y  GG  TQVKMP
Sbjct: 250 HI----GDVSGLGTYQSGGIFTQVKMP 272

[95][TOP]
>UniRef100_A9REZ6 Ubiquitin-activating enzyme E1 n=1 Tax=Physcomitrella patens subsp.
           patens RepID=A9REZ6_PHYPA
          Length = 1058

 Score =  112 bits (279), Expect = 2e-23
 Identities = 61/166 (36%), Positives = 94/166 (56%), Gaps = 2/166 (1%)
 Frame = +2

Query: 17  AADAAASVADAVAAVAAKYTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSI 190
           A D   S  +    + + ++VVV  +  L     +D  C   E  + F+     GVFGS+
Sbjct: 142 AVDVNTSSGEITEQLLSAHSVVVFTDIGLDKAIEIDDFCHRHEPVIAFIKADIRGVFGSV 201

Query: 191 FNDFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGA 370
           F DFGP F V DV+GE+P + ++++I+  + +  +V C+D++R + + GD V F+EV G 
Sbjct: 202 FCDFGPSFNVVDVDGEEPHTGIVASIS--NDNPALVTCVDDERLELQDGDLVKFSEVHGM 259

Query: 371 TGLNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
             LNDGK R +K   PY+F L    E+    GAY +GG  TQ+K+P
Sbjct: 260 PELNDGKPRRVKGTRPYSFLL---EEDTTGYGAYEKGGIVTQIKLP 302

[96][TOP]
>UniRef100_B0W2P8 Ubiquitin-activating enzyme E1 n=1 Tax=Culex quinquefasciatus
           RepID=B0W2P8_CULQU
          Length = 1102

 Score =  112 bits (279), Expect = 2e-23
 Identities = 65/160 (40%), Positives = 87/160 (54%)
 Frame = +2

Query: 29  AASVADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGP 208
           +A   D       ++  VVL   + A Q  +       ++  +     G+F  IF DFG 
Sbjct: 196 SAYTGDLTEDFLLRFRCVVLTLTAPAEQHRIAEITHRHNIALIIADTRGLFSQIFCDFGT 255

Query: 209 KFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDG 388
            F V D  G  P S M+++IT +   + +V CLDE RH FE GD+VTFTEV+G T LN  
Sbjct: 256 NFTVYDQTGANPGSAMVASITSDP--ESIVTCLDENRHGFEDGDYVTFTEVEGMTELNGC 313

Query: 389 KSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
              +IKVLGPYTF++     + +   AYVRGG  TQVKMP
Sbjct: 314 DPIKIKVLGPYTFSI----GDTSKNTAYVRGGIVTQVKMP 349

[97][TOP]
>UniRef100_Q5BBA6 Ubiquitin-activating enzyme E1 n=1 Tax=Emericella nidulans
           RepID=Q5BBA6_EMENI
          Length = 1491

 Score =  112 bits (279), Expect = 2e-23
 Identities = 59/147 (40%), Positives = 81/147 (55%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           +Y  +VL    L  Q V+   C +  +       +G+FG +FNDFG  F V D  GE P 
Sbjct: 178 RYQAIVLTLTPLKEQLVIADFCHKNGIYLTIADTFGLFGYLFNDFGKNFTVGDSTGEDP- 236

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
              +  I  +  +D +V+ LDE RH  E GD VTFTEV+G  GLN+   R++ V GPY+F
Sbjct: 237 ---VGGIVADISEDGLVSALDETRHGLEDGDFVTFTEVKGMEGLNNSAPRKVTVKGPYSF 293

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
            +     +V+ +G Y  GG  TQVKMP
Sbjct: 294 TI----GDVSGLGTYQGGGLFTQVKMP 316

[98][TOP]
>UniRef100_C8VMA9 E1 ubiquitin activating enzyme (Eurofung) n=1 Tax=Aspergillus
           nidulans FGSC A4 RepID=C8VMA9_EMENI
          Length = 1033

 Score =  112 bits (279), Expect = 2e-23
 Identities = 59/147 (40%), Positives = 81/147 (55%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           +Y  +VL    L  Q V+   C +  +       +G+FG +FNDFG  F V D  GE P 
Sbjct: 135 RYQAIVLTLTPLKEQLVIADFCHKNGIYLTIADTFGLFGYLFNDFGKNFTVGDSTGEDP- 193

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
              +  I  +  +D +V+ LDE RH  E GD VTFTEV+G  GLN+   R++ V GPY+F
Sbjct: 194 ---VGGIVADISEDGLVSALDETRHGLEDGDFVTFTEVKGMEGLNNSAPRKVTVKGPYSF 250

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
            +     +V+ +G Y  GG  TQVKMP
Sbjct: 251 TI----GDVSGLGTYQGGGLFTQVKMP 273

[99][TOP]
>UniRef100_C5YQ24 Ubiquitin-activating enzyme E1 n=1 Tax=Sorghum bicolor
           RepID=C5YQ24_SORBI
          Length = 1052

 Score =  111 bits (278), Expect = 2e-23
 Identities = 58/150 (38%), Positives = 91/150 (60%), Gaps = 2/150 (1%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGE 238
           + +  VV  + S       D  C   +  + F+     G+FGS++ DFGP+F V DV+GE
Sbjct: 152 SNFQAVVFTDISTEKAVEFDDYCHSHQPPIAFIKSEVRGLFGSVYCDFGPEFTVLDVDGE 211

Query: 239 QPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGP 418
           +P + ++++I+  + +  +V+C+D++R +F+ GD V F+EV G T LNDGK R+IK   P
Sbjct: 212 EPHTGIVASIS--NDNPALVSCVDDERLEFQDGDLVVFSEVHGMTELNDGKPRKIKSARP 269

Query: 419 YTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           Y+F L    E+  + G Y+RGG  TQVK P
Sbjct: 270 YSFTL---EEDTTSYGTYIRGGIVTQVKPP 296

[100][TOP]
>UniRef100_Q28Y05 Ubiquitin-activating enzyme E1 n=1 Tax=Drosophila pseudoobscura
           pseudoobscura RepID=Q28Y05_DROPS
          Length = 1184

 Score =  111 bits (278), Expect = 2e-23
 Identities = 63/147 (42%), Positives = 84/147 (57%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           ++ VVVL N   A Q  +     E  +  +     G+F  +F DFG  F + D +G QP 
Sbjct: 297 QFRVVVLTNSDTAEQERIGKFAHENGIALIIADTRGLFAKVFCDFGESFTIYDQDGAQPV 356

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S MI++IT +     VV CLDE RH F  GD+VTF+EVQG   LN  +  +I VLGPYTF
Sbjct: 357 STMIASITHDAQG--VVTCLDETRHGFNDGDYVTFSEVQGMQQLNGCQPIKITVLGPYTF 414

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     + ++ G Y  GG ATQVKMP
Sbjct: 415 SI----GDTSSYGEYKSGGVATQVKMP 437

[101][TOP]
>UniRef100_B4GGE0 GL17327 n=1 Tax=Drosophila persimilis RepID=B4GGE0_DROPE
          Length = 502

 Score =  111 bits (278), Expect = 2e-23
 Identities = 63/147 (42%), Positives = 84/147 (57%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           ++ VVVL N   A Q  +     E  +  +     G+F  +F DFG  F + D +G QP 
Sbjct: 297 QFRVVVLTNSDTAEQERIGKFAHENGIALIIADTRGLFAKVFCDFGESFTIYDQDGAQPV 356

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S MI++IT +     VV CLDE RH F  GD+VTF+EVQG   LN  +  +I VLGPYTF
Sbjct: 357 STMIASITHDAQG--VVTCLDETRHGFNDGDYVTFSEVQGMQQLNGCQPIKITVLGPYTF 414

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     + ++ G Y  GG ATQVKMP
Sbjct: 415 SI----GDTSSYGEYKSGGVATQVKMP 437

[102][TOP]
>UniRef100_B0CUX8 Predicted protein n=1 Tax=Laccaria bicolor S238N-H82
           RepID=B0CUX8_LACBS
          Length = 1008

 Score =  111 bits (278), Expect = 2e-23
 Identities = 66/163 (40%), Positives = 86/163 (52%), Gaps = 1/163 (0%)
 Frame = +2

Query: 23  DAAASVADAVAAVAAK-YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFND 199
           D      DA+     K + VVVL       Q  ++    +  V F+S    G+FGS F D
Sbjct: 108 DLGGMPGDAITVDLIKGFQVVVLCGVPHRKQLEINDWTHQNGVPFISTETRGLFGSAFTD 167

Query: 200 FGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGL 379
           FG KF   D  GEQP + MI +++    ++ +V CLDE RH  E GD VTFTEVQG   L
Sbjct: 168 FGAKFACVDPTGEQPLTGMIVSVSKPQDNEGLVTCLDETRHGLEDGDFVTFTEVQGMRQL 227

Query: 380 NDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           ND + R++ V GPYTF +     + +    Y  GG  TQVKMP
Sbjct: 228 NDCEPRKVTVKGPYTFTI----GDTSKFDDYKTGGIFTQVKMP 266

[103][TOP]
>UniRef100_Q75VJ9 Ubiquitin-activating enzyme E1 n=1 Tax=Nicotiana tabacum
           RepID=Q75VJ9_TOBAC
          Length = 1080

 Score =  111 bits (277), Expect = 3e-23
 Identities = 59/150 (39%), Positives = 91/150 (60%), Gaps = 2/150 (1%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACREAD--VKFMSVGAYGVFGSIFNDFGPKFVVSDVNGE 238
           + +  VV  + SL      D  C +    + F+     G+FGS+F DFGP+F ++DV+GE
Sbjct: 180 SNFQAVVFTDISLEKAVKFDDYCHQHQPPIAFIKAEVRGLFGSVFCDFGPEFTIADVDGE 239

Query: 239 QPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGP 418
            P + +I++I+  + +  +V C+D++R +F+ GD V F+EV+G T LNDGK R+IK   P
Sbjct: 240 DPHTGIIASIS--NDNPALVGCIDDERLEFQDGDLVIFSEVRGMTELNDGKPRKIKNARP 297

Query: 419 YTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           Y+F +    E+ +   AY RGG  TQVK P
Sbjct: 298 YSFTI---EEDTSNYAAYERGGIVTQVKEP 324

[104][TOP]
>UniRef100_P93393 Ubiquitin-activating enzyme E1 n=1 Tax=Nicotiana tabacum
           RepID=P93393_TOBAC
          Length = 1080

 Score =  111 bits (277), Expect = 3e-23
 Identities = 59/150 (39%), Positives = 91/150 (60%), Gaps = 2/150 (1%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACREAD--VKFMSVGAYGVFGSIFNDFGPKFVVSDVNGE 238
           + +  VV  + SL      D  C +    + F+     G+FGS+F DFGP+F ++DV+GE
Sbjct: 180 SNFQAVVFTDISLEKAVKFDDYCHQHQPPIAFIKAEVRGLFGSVFCDFGPEFTIADVDGE 239

Query: 239 QPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGP 418
            P + +I++I+  + +  +V C+D++R +F+ GD V F+EV+G T LNDGK R+IK   P
Sbjct: 240 DPHTGIIASIS--NDNPALVGCIDDERLEFQDGDLVIFSEVRGMTELNDGKPRKIKNARP 297

Query: 419 YTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           Y+F +    E+ +   AY RGG  TQVK P
Sbjct: 298 YSFTI---EEDTSNYAAYERGGIVTQVKEP 324

[105][TOP]
>UniRef100_C1G554 Ubiquitin-activating enzyme E1 n=1 Tax=Paracoccidioides
           brasiliensis Pb18 RepID=C1G554_PARBD
          Length = 1127

 Score =  111 bits (277), Expect = 3e-23
 Identities = 61/147 (41%), Positives = 87/147 (59%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           KY VVVL +  L  Q V+   C + ++  +    +G+FG IF DFG  F V D  GE P 
Sbjct: 225 KYQVVVLTSTPLRDQLVIAEYCHQNNIYVIITDTFGLFGYIFTDFGENFTVVDPTGEDPT 284

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S +++ IT E+G   +V+  DE RH     D+VTFTEV+G   LN+ + R++ + GPYTF
Sbjct: 285 SGIVAGIT-EEG---LVSASDETRHGLGEDDYVTFTEVKGMEKLNNAEPRKVDIKGPYTF 340

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +V+ +G Y  GG  TQVKMP
Sbjct: 341 SI----GDVSGLGTYHSGGIYTQVKMP 363

[106][TOP]
>UniRef100_C0RZU5 Ubiquitin-activating enzyme E1 n=1 Tax=Paracoccidioides
           brasiliensis Pb03 RepID=C0RZU5_PARBP
          Length = 1030

 Score =  111 bits (277), Expect = 3e-23
 Identities = 61/147 (41%), Positives = 87/147 (59%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           KY VVVL +  L  Q V+   C + ++  +    +G+FG IF DFG  F V D  GE P 
Sbjct: 128 KYQVVVLTSTPLRDQLVIAEYCHQNNIYVIITDTFGLFGYIFTDFGENFTVVDPTGEDPT 187

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S +++ IT E+G   +V+  DE RH     D+VTFTEV+G   LN+ + R++ + GPYTF
Sbjct: 188 SGIVAGIT-EEG---LVSASDETRHGLGEDDYVTFTEVKGMEKLNNAEPRKVDIKGPYTF 243

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +V+ +G Y  GG  TQVKMP
Sbjct: 244 SI----GDVSGLGTYHSGGIYTQVKMP 266

[107][TOP]
>UniRef100_C5DC89 Ubiquitin-activating enzyme E1 n=1 Tax=Lachancea thermotolerans CBS
           6340 RepID=C5DC89_LACTC
          Length = 1015

 Score =  110 bits (276), Expect = 4e-23
 Identities = 60/148 (40%), Positives = 88/148 (59%), Gaps = 1/148 (0%)
 Frame = +2

Query: 68  KYTVVVLVNQ-SLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           KY V+V      L  +  ++  C  A +KF++    G+FGS+FNDFG +F V D  GE+P
Sbjct: 115 KYQVIVATETLPLERKIELNNFCHAAGIKFIATETRGLFGSVFNDFGEEFTVVDPTGEEP 174

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
           +S ++S I      D  V  LD+ RH+ E G++V F+EV+G   LNDG   +++VLGP+ 
Sbjct: 175 QSGIVSDIE----PDGTVTMLDDNRHNLEDGNYVKFSEVEGLEKLNDGTPYKVEVLGPFA 230

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F +   +E    +G Y +GG  TQVKMP
Sbjct: 231 FRIGSVKE----LGTYKKGGVFTQVKMP 254

[108][TOP]
>UniRef100_C1GZI8 Ubiquitin-activating enzyme E1 n=1 Tax=Paracoccidioides
           brasiliensis Pb01 RepID=C1GZI8_PARBA
          Length = 1030

 Score =  110 bits (276), Expect = 4e-23
 Identities = 61/147 (41%), Positives = 87/147 (59%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           KY VVVL +  L  Q V+   C + ++  +    +G+FG IF DFG  F V D  GE P 
Sbjct: 128 KYQVVVLTSTPLRDQLVIAEYCHKNNIYVIITDTFGLFGYIFTDFGENFTVVDPTGEDPT 187

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S +++ IT E+G   +V+  DE RH     D+VTFTEV+G   LN+ + R++ + GPYTF
Sbjct: 188 SGIVAGIT-EEG---LVSASDETRHGLGEDDYVTFTEVKGMEKLNNAEPRKVDIKGPYTF 243

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +V+ +G Y  GG  TQVKMP
Sbjct: 244 SI----GDVSGLGTYHSGGIYTQVKMP 266

[109][TOP]
>UniRef100_P31252 Ubiquitin-activating enzyme E1 3 n=1 Tax=Triticum aestivum
           RepID=UBE13_WHEAT
          Length = 1053

 Score =  110 bits (276), Expect = 4e-23
 Identities = 58/150 (38%), Positives = 92/150 (61%), Gaps = 2/150 (1%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGE 238
           +K+  VV  +  L      D  C   +  + F+     G+FGS+F DFGPKF V DV+GE
Sbjct: 153 SKFQAVVFTDIDLDKAYEFDDYCHNHQPPISFIKSEVCGLFGSVFCDFGPKFTVLDVDGE 212

Query: 239 QPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGP 418
            P + +I++I+  + +  +++C+D++R +F+ GD V F+EV G T LNDGK R++K   P
Sbjct: 213 DPHTGIIASIS--NDNPALISCVDDERLEFQDGDLVVFSEVHGMTELNDGKPRKVKNARP 270

Query: 419 YTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++F++    E+ +  G YV+GG  TQVK P
Sbjct: 271 FSFSI---EEDTSNFGIYVKGGIVTQVKEP 297

[110][TOP]
>UniRef100_UPI00015B489C PREDICTED: similar to ubiquitin-activating enzyme E1 n=1
           Tax=Nasonia vitripennis RepID=UPI00015B489C
          Length = 1281

 Score =  110 bits (274), Expect = 7e-23
 Identities = 59/150 (39%), Positives = 87/150 (58%)
 Frame = +2

Query: 59  VAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGE 238
           +   ++VVV+   SL  Q  +       ++  +     G+F  IF DFG  F V D  GE
Sbjct: 232 ILKNFSVVVITETSLDEQLRISEITHSNNIALIIGETRGLFSQIFCDFGDSFSVIDATGE 291

Query: 239 QPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGP 418
            P S M+++I+ ++    VV CLD+ RH  E GD+VTF+EVQG + LN  + R+IKVLGP
Sbjct: 292 PPISAMVASISRDNQG--VVTCLDDTRHGMEDGDYVTFSEVQGMSELNGCEPRKIKVLGP 349

Query: 419 YTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           YTF++     + +    Y++GG  TQ+KMP
Sbjct: 350 YTFSI----GDTSMYSEYIQGGIVTQIKMP 375

[111][TOP]
>UniRef100_B9SKZ1 Ubiquitin-activating enzyme E1 n=1 Tax=Ricinus communis
           RepID=B9SKZ1_RICCO
          Length = 1100

 Score =  110 bits (274), Expect = 7e-23
 Identities = 62/148 (41%), Positives = 88/148 (59%), Gaps = 2/148 (1%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           +  VV  + SL      D  C   +  + F+     G+FGSIF DFGP F V D +GE P
Sbjct: 202 FQAVVFTDISLEKAVEFDDYCHNHQPPIAFIKSEVRGLFGSIFCDFGPDFTVLDADGEDP 261

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
            + +I++I+  + +  +VAC+D++R +F+ GD V F+EVQG   LNDGK R++K   PY+
Sbjct: 262 HTGIIASIS--NDNPALVACVDDERLEFQDGDLVVFSEVQGMPELNDGKPRKVKNSRPYS 319

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F +    E+    GAYVRGG  TQVK P
Sbjct: 320 FQI---DEDTTNHGAYVRGGIVTQVKEP 344

[112][TOP]
>UniRef100_C5X6F4 Ubiquitin-activating enzyme E1 n=1 Tax=Sorghum bicolor
           RepID=C5X6F4_SORBI
          Length = 1066

 Score =  109 bits (273), Expect = 9e-23
 Identities = 57/150 (38%), Positives = 91/150 (60%), Gaps = 2/150 (1%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGE 238
           +K+  VV  + SL      D  C   +  + F+     G+FGS+F DFGP+F V DV+GE
Sbjct: 166 SKFQAVVFTDISLEKAYEFDDYCHSHQPPISFIKAEVCGLFGSVFCDFGPEFTVLDVDGE 225

Query: 239 QPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGP 418
            P + +I++I+  +    +V+C+D++R +F+ GD V F+EVQG   LNDGK R++K   P
Sbjct: 226 DPHTGIIASIS--NDSPAMVSCVDDERLEFQDGDLVVFSEVQGMAELNDGKPRKVKNARP 283

Query: 419 YTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++F++    E+ ++ G Y +GG   QVK P
Sbjct: 284 FSFSI---EEDTSSYGVYTKGGIVAQVKEP 310

[113][TOP]
>UniRef100_A3LQ33 Ubiquitin-activating enzyme E1 n=1 Tax=Pichia stipitis
           RepID=A3LQ33_PICST
          Length = 1021

 Score =  109 bits (273), Expect = 9e-23
 Identities = 60/157 (38%), Positives = 84/157 (53%)
 Frame = +2

Query: 38  VADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFV 217
           + D   A  + Y  +V  N SL  Q  ++    E D+ F++    G+FG +F DFG  F 
Sbjct: 112 ITDLSEATLSNYKCIVATNLSLEEQVRINTFTHERDIGFIAADNRGLFGQLFVDFGSSFT 171

Query: 218 VSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSR 397
           + D  GE+P + ++S I      D  V  LD+ RH  E GD+V FTEV+G   LNDG   
Sbjct: 172 IIDQTGEEPHTGIVSDIEA----DGTVTMLDDNRHGLEDGDYVKFTEVEGMPKLNDGNPH 227

Query: 398 EIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +I+VLGPY F +        + G YV+ G  TQVK+P
Sbjct: 228 KIEVLGPYAFRI----NIDESYGKYVKNGLYTQVKVP 260

[114][TOP]
>UniRef100_O94609 Ubiquitin-activating enzyme E1 1 n=1 Tax=Schizosaccharomyces pombe
           RepID=UBA1_SCHPO
          Length = 1012

 Score =  109 bits (273), Expect = 9e-23
 Identities = 62/159 (38%), Positives = 94/159 (59%), Gaps = 1/159 (0%)
 Frame = +2

Query: 35  SVADAVAAVAAK-YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPK 211
           SV D ++    K +  VV+   SL  Q  ++    +  + +++  + G+FGSIF DFG  
Sbjct: 110 SVVDELSTEYLKNFKCVVVTETSLTKQLEINDFTHKNHIAYIAADSRGLFGSIFCDFGEN 169

Query: 212 FVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGK 391
           F+ +D +G +P + MI++IT    DD VV  L+E RH  E GD V FTEV+G  GLNDG 
Sbjct: 170 FICTDTDGNEPLTGMIASIT----DDGVVTMLEETRHGLENGDFVKFTEVKGMPGLNDGT 225

Query: 392 SREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
            R+++V GPYTF++   ++    +G+    G  TQVK+P
Sbjct: 226 PRKVEVKGPYTFSIGSVKD----LGSAGYNGVFTQVKVP 260

[115][TOP]
>UniRef100_Q8T0L3 Ubiquitin-activating enzyme E1 n=1 Tax=Drosophila melanogaster
           RepID=Q8T0L3_DROME
          Length = 1191

 Score =  109 bits (272), Expect = 1e-22
 Identities = 63/147 (42%), Positives = 82/147 (55%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           K+ VVVL N     Q  +     E  +  +     G+F  +F DFG  F + D +G QP 
Sbjct: 303 KFRVVVLTNSDGEEQQRIAKFAHENGIALIIAETRGLFAKVFCDFGESFTIYDQDGTQPI 362

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S MI++IT +     VV CLDE RH F  GD+VTF+EVQG   LN  +  +I VLGPYTF
Sbjct: 363 STMIASITHDAQG--VVTCLDETRHGFNDGDYVTFSEVQGMQELNGCQPLKITVLGPYTF 420

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     + +  G Y  GG ATQVKMP
Sbjct: 421 SI----GDTSKFGEYKSGGVATQVKMP 443

[116][TOP]
>UniRef100_B4QHP5 Ubiquitin-activating enzyme E1 n=1 Tax=Drosophila simulans
           RepID=B4QHP5_DROSI
          Length = 1191

 Score =  109 bits (272), Expect = 1e-22
 Identities = 63/147 (42%), Positives = 82/147 (55%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           K+ VVVL N     Q  +     E  +  +     G+F  +F DFG  F + D +G QP 
Sbjct: 303 KFRVVVLTNSDGEEQQRIAKFAHENGIALIIAETRGLFAKVFCDFGESFTIYDQDGTQPI 362

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S MI++IT +     VV CLDE RH F  GD+VTF+EVQG   LN  +  +I VLGPYTF
Sbjct: 363 STMIASITHDAQG--VVTCLDETRHGFNDGDYVTFSEVQGMQELNGCQPLKITVLGPYTF 420

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     + +  G Y  GG ATQVKMP
Sbjct: 421 SI----GDTSKFGEYKSGGVATQVKMP 443

[117][TOP]
>UniRef100_B4HT27 Ubiquitin-activating enzyme E1 n=1 Tax=Drosophila sechellia
           RepID=B4HT27_DROSE
          Length = 1191

 Score =  109 bits (272), Expect = 1e-22
 Identities = 63/147 (42%), Positives = 82/147 (55%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           K+ VVVL N     Q  +     E  +  +     G+F  +F DFG  F + D +G QP 
Sbjct: 303 KFRVVVLTNSDGEEQQRIAKFAHENGIALIIAETRGLFAKVFCDFGESFTIYDQDGTQPI 362

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S MI++IT +     VV CLDE RH F  GD+VTF+EVQG   LN  +  +I VLGPYTF
Sbjct: 363 STMIASITHDAQG--VVTCLDETRHGFNDGDYVTFSEVQGMQELNGCQPLKITVLGPYTF 420

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     + +  G Y  GG ATQVKMP
Sbjct: 421 SI----GDTSKFGEYKSGGVATQVKMP 443

[118][TOP]
>UniRef100_UPI00019835E9 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
           RepID=UPI00019835E9
          Length = 1018

 Score =  108 bits (271), Expect = 2e-22
 Identities = 54/121 (44%), Positives = 80/121 (66%)
 Frame = +2

Query: 146 VKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHD 325
           + F+     G+FGS+F DFGP+F V DV+GE+P + +I++I+  + +  +V+C+D++R +
Sbjct: 147 IAFIKAEVRGLFGSVFCDFGPEFTVFDVDGEEPHTGIIASIS--NDNPALVSCVDDERLE 204

Query: 326 FETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKM 505
           F+ GD V F+EV G T LNDGK R+IK   PY+F L    E+    G Y +GG  TQVK 
Sbjct: 205 FQDGDLVVFSEVHGMTELNDGKPRKIKNARPYSFTL---EEDTTNFGTYEKGGIVTQVKQ 261

Query: 506 P 508
           P
Sbjct: 262 P 262

[119][TOP]
>UniRef100_A7NYA8 Ubiquitin-activating enzyme E1 n=1 Tax=Vitis vinifera
           RepID=A7NYA8_VITVI
          Length = 1089

 Score =  108 bits (271), Expect = 2e-22
 Identities = 54/121 (44%), Positives = 80/121 (66%)
 Frame = +2

Query: 146 VKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHD 325
           + F+     G+FGS+F DFGP+F V DV+GE+P + +I++I+  + +  +V+C+D++R +
Sbjct: 216 IAFIKAEVRGLFGSVFCDFGPEFTVFDVDGEEPHTGIIASIS--NDNPALVSCVDDERLE 273

Query: 326 FETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKM 505
           F+ GD V F+EV G T LNDGK R+IK   PY+F L    E+    G Y +GG  TQVK 
Sbjct: 274 FQDGDLVVFSEVHGMTELNDGKPRKIKNARPYSFTL---EEDTTNFGTYEKGGIVTQVKQ 330

Query: 506 P 508
           P
Sbjct: 331 P 331

[120][TOP]
>UniRef100_B4JVX7 Ubiquitin-activating enzyme E1 n=1 Tax=Drosophila grimshawi
           RepID=B4JVX7_DROGR
          Length = 1244

 Score =  108 bits (271), Expect = 2e-22
 Identities = 61/147 (41%), Positives = 83/147 (56%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           K+ V+VL N     Q  +     + ++  +     G+F  +F DFG KF + D +G QP 
Sbjct: 358 KFRVIVLTNSDAEEQQRIAQFAHDNNIALIIAETRGLFAKVFCDFGDKFTIYDQDGAQPV 417

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S MI++IT +     VV CLDE RH F  GD+VTF+EVQG   LN  +  +I VLGPYTF
Sbjct: 418 STMIASITHDAQG--VVTCLDETRHGFNDGDYVTFSEVQGMQELNGCQPIKISVLGPYTF 475

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     + +   AY   G ATQVKMP
Sbjct: 476 SI----GDTSKFSAYKSAGVATQVKMP 498

[121][TOP]
>UniRef100_B3N6X5 Ubiquitin-activating enzyme E1 n=1 Tax=Drosophila erecta
           RepID=B3N6X5_DROER
          Length = 1189

 Score =  108 bits (271), Expect = 2e-22
 Identities = 63/151 (41%), Positives = 83/151 (54%)
 Frame = +2

Query: 56  AVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNG 235
           A   ++ VVVL N     Q  +     E  +  +     G+F  +F DFG  F + D +G
Sbjct: 297 AFLRRFRVVVLTNSDGEEQQRIGKIAHENGIALIIAETRGLFAKVFCDFGESFTIYDQDG 356

Query: 236 EQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLG 415
            QP S MI++IT +     VV CLDE RH F  GD+VTF+EVQG   LN  +  +I VLG
Sbjct: 357 TQPISTMIASITHDAQG--VVTCLDETRHGFNDGDYVTFSEVQGMQELNGCQPIKITVLG 414

Query: 416 PYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           PYTF++     + +  G Y  GG ATQVKMP
Sbjct: 415 PYTFSI----GDTSKFGEYKSGGVATQVKMP 441

[122][TOP]
>UniRef100_A2R5Y8 Ubiquitin-activating enzyme E1 n=1 Tax=Aspergillus niger CBS 513.88
           RepID=A2R5Y8_ASPNC
          Length = 1034

 Score =  108 bits (271), Expect = 2e-22
 Identities = 60/147 (40%), Positives = 85/147 (57%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           +Y  VVL    L  Q  +   C +  +       +G+FG +FNDFG  F V D  GE+P 
Sbjct: 134 RYQAVVLTLTPLKDQLAIADFCHKNGIYLTITDTFGLFGYLFNDFGKNFTVGDATGEEPV 193

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S +++AI  E+G   +V+ LDE RH  E GD VTF+E++G  GLN    R++ V GPYTF
Sbjct: 194 SGIVAAID-ENG---LVSALDETRHGLEDGDFVTFSEIKGMEGLNGCAPRKVTVKGPYTF 249

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +V+ +G Y  GG  +QVKMP
Sbjct: 250 SI----GDVSDLGTYQSGGIYSQVKMP 272

[123][TOP]
>UniRef100_B2WGD4 Ubiquitin-activating enzyme E1 n=1 Tax=Pyrenophora tritici-repentis
           Pt-1C-BFP RepID=B2WGD4_PYRTR
          Length = 1046

 Score =  108 bits (270), Expect = 2e-22
 Identities = 60/147 (40%), Positives = 87/147 (59%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           ++ V+VL + +L  Q  +   C +  +  +    YG+FG+IF DFG  F V D  GE   
Sbjct: 134 QFQVIVLTDTALEDQIKIADYCHDNGIFIVITDTYGLFGTIFTDFGKNFTVGDPTGENVS 193

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           + +I+ I  E+G   +V+ LDE RH  E GD VTF+EV+G  GLN    R+I+V GPYTF
Sbjct: 194 TGIIAGID-EEG---IVSALDETRHGLEDGDWVTFSEVEGMEGLNGCAPRKIEVKGPYTF 249

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +V+ +G Y +GG   QVKMP
Sbjct: 250 SI----GDVSGLGEYKKGGQFIQVKMP 272

[124][TOP]
>UniRef100_B4LJA5 Ubiquitin-activating enzyme E1 n=1 Tax=Drosophila virilis
           RepID=B4LJA5_DROVI
          Length = 1230

 Score =  108 bits (269), Expect = 3e-22
 Identities = 61/148 (41%), Positives = 84/148 (56%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           +++ V+VL N   A Q  +       ++  +     G+F  +F DFG KF + D +G QP
Sbjct: 343 SQFRVIVLTNSDAAEQQRIGQFAHANNIALIIAETRGLFAKVFCDFGDKFTIYDQDGAQP 402

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
            S MI++IT +     VV CLDE RH F  GD+VTF+EVQG   LN  +  +I VLGPYT
Sbjct: 403 VSTMIASITHDAQG--VVTCLDETRHGFNDGDYVTFSEVQGMHQLNGCQPIKITVLGPYT 460

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F++     + +    Y  GG ATQVKMP
Sbjct: 461 FSI----GDTSKFDEYKSGGVATQVKMP 484

[125][TOP]
>UniRef100_C1EAD2 Ubiquitin-activating enzyme E1 n=1 Tax=Micromonas sp. RCC299
           RepID=C1EAD2_9CHLO
          Length = 1014

 Score =  107 bits (268), Expect = 4e-22
 Identities = 62/162 (38%), Positives = 89/162 (54%)
 Frame = +2

Query: 17  AADAAASVADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFN 196
           A     +  +    +  ++TVVV     LA    VDA C    + F+     GVFGS+F 
Sbjct: 98  AVTVTVNTGEITDDLCKQHTVVVCTEVPLAKAKEVDAFCHANGIAFIRGDVRGVFGSLFC 157

Query: 197 DFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATG 376
           DFGP F V DV+GE+P S ++++I+  +    +V C+D++R + + G  V F EV+G T 
Sbjct: 158 DFGPGFDVLDVDGEEPHSCIVASIS--NDATPLVTCVDDERVELQDGQRVLFAEVKGMTE 215

Query: 377 LNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVK 502
           LNDG  R IK +  ++F L    E+  A G Y  GG ATQVK
Sbjct: 216 LNDGVPRRIKNVKAHSFEL---EEDTTAYGQYTGGGIATQVK 254

[126][TOP]
>UniRef100_B9SKU8 Ubiquitin-activating enzyme E1 n=1 Tax=Ricinus communis
           RepID=B9SKU8_RICCO
          Length = 1107

 Score =  107 bits (267), Expect = 5e-22
 Identities = 52/121 (42%), Positives = 81/121 (66%)
 Frame = +2

Query: 146 VKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHD 325
           + F+     G+FGS+F DFGP+F V DV+GE+P + ++++I+  + +  +V+C+D++R +
Sbjct: 236 ISFIKAEVRGLFGSVFCDFGPEFTVFDVDGEEPHTGIVASIS--NDNPALVSCVDDERLE 293

Query: 326 FETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKM 505
           F+ GD V F+E+ G T LNDGK R+IK   PY+F+L    E+    G Y +GG  TQVK 
Sbjct: 294 FQDGDLVVFSEIHGMTELNDGKPRKIKNARPYSFSL---DEDTTNFGTYEKGGIVTQVKP 350

Query: 506 P 508
           P
Sbjct: 351 P 351

[127][TOP]
>UniRef100_B4NWJ4 Ubiquitin-activating enzyme E1 n=1 Tax=Drosophila yakuba
           RepID=B4NWJ4_DROYA
          Length = 1189

 Score =  107 bits (267), Expect = 5e-22
 Identities = 62/147 (42%), Positives = 81/147 (55%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           K+ VVVL N     Q  +     E  +  +     G+F  +F DFG  F + D +G QP 
Sbjct: 301 KFRVVVLTNSDGEEQQRIGKFAHENGIALIIAETRGLFAKVFCDFGESFTIYDQDGTQPI 360

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S MI++IT +     VV CLDE RH F  GD+VTF+EVQG   LN  +  +I VLGPYTF
Sbjct: 361 STMIASITHDAQG--VVTCLDETRHGFNDGDYVTFSEVQGMQELNGCQPLKITVLGPYTF 418

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     + +    Y  GG ATQVKMP
Sbjct: 419 SI----GDTSKFAEYKSGGVATQVKMP 441

[128][TOP]
>UniRef100_C5KEK7 Ubiquitin-activating enzyme E1 n=1 Tax=Perkinsus marinus ATCC 50983
           RepID=C5KEK7_9ALVE
          Length = 1046

 Score =  107 bits (266), Expect = 6e-22
 Identities = 59/152 (38%), Positives = 92/152 (60%), Gaps = 1/152 (0%)
 Frame = +2

Query: 56  AVAAKYTVVVLVNQSLATQTV-VDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVN 232
           A  + + V+VL +     + V ++  CR+ ++ F++   YG+ G IF D+G  FVV D +
Sbjct: 113 AALSDFDVIVLCDVHNRDERVRINTYCRQHNIGFIATDVYGLAGRIFVDYGDNFVVRDKD 172

Query: 233 GEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVL 412
           GE+ R+ ++S IT ++  +V+     E+RH F  GD+VTFTEV+G T LN     +IKV 
Sbjct: 173 GEECRTAIVSGITQDEHAEVIT--YGERRHGFHNGDYVTFTEVEGMTELNGCDPVQIKVT 230

Query: 413 GPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           GPY+F++    ++     AY+R G  TQVKMP
Sbjct: 231 GPYSFSI---DKDTRDYHAYIREGTVTQVKMP 259

[129][TOP]
>UniRef100_B9GGR5 Ubiquitin-activating enzyme E1 n=1 Tax=Populus trichocarpa
           RepID=B9GGR5_POPTR
          Length = 1018

 Score =  106 bits (265), Expect = 8e-22
 Identities = 57/149 (38%), Positives = 90/149 (60%), Gaps = 2/149 (1%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQ 241
           K+  VV  + +L      +  C   +  + F+     G+FGS+F DFGP+F V DV+GE+
Sbjct: 119 KFQAVVFTDLNLDKAIEFNDYCHNHKPPISFIKAEVRGLFGSVFCDFGPEFTVFDVDGEE 178

Query: 242 PRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPY 421
           P + +I++I+  + +  +V+C+D++R +F+ GD V F+EV+G T +NDGK R+IK   PY
Sbjct: 179 PHTGIIASIS--NDNPALVSCVDDERLEFQDGDLVVFSEVKGMTEMNDGKPRKIKNSRPY 236

Query: 422 TFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +F L    E+      Y +GG  TQVK P
Sbjct: 237 SFNL---EEDTTNFATYEKGGIVTQVKQP 262

[130][TOP]
>UniRef100_B4KTU8 Ubiquitin-activating enzyme E1 n=1 Tax=Drosophila mojavensis
           RepID=B4KTU8_DROMO
          Length = 1198

 Score =  106 bits (265), Expect = 8e-22
 Identities = 60/147 (40%), Positives = 81/147 (55%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           ++ V+VL N     Q  +       ++  +     G+F  +F DFG KF + D +G QP 
Sbjct: 312 RFRVIVLTNSDAIEQHRIGEFAHANNIALIIAETRGLFAKVFCDFGEKFTIYDQDGAQPV 371

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S MI++IT +     VV CLDE RH F  GD+VTF+EVQG   LN  +   I VLGPYTF
Sbjct: 372 STMIASITHDTQG--VVTCLDETRHGFNDGDYVTFSEVQGMHQLNGCQPIRINVLGPYTF 429

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     + +    Y  GG ATQVKMP
Sbjct: 430 SI----GDTSGFDEYKSGGVATQVKMP 452

[131][TOP]
>UniRef100_UPI0000E4ED71 Ubiquitin-activating enzyme E1 homolog (D8). n=2 Tax=Danio rerio
           RepID=UPI0000E4ED71
          Length = 905

 Score =  106 bits (264), Expect = 1e-21
 Identities = 63/148 (42%), Positives = 85/148 (57%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           +K+ VVVL +  L  Q  V A C   ++KF+     G+ G +F DFG  F V D NG+ P
Sbjct: 113 SKFQVVVLTSSPLDEQLRVGAFCHSNNIKFIVADTRGLCGQLFCDFGESFEVIDTNGDPP 172

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
            S MIS I+ E+    VV C DE+ H+F  G  VTF+EVQG T LN+    EIKV G Y+
Sbjct: 173 VSAMISHISKENPG--VVNCTDEESHEFTDGMFVTFSEVQGMTELNNYGPVEIKVRGTYS 230

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F++     + +    YV+ G AT+VK P
Sbjct: 231 FSIC----DTSNFSDYVKCGVATEVKQP 254

[132][TOP]
>UniRef100_UPI0000E46080 PREDICTED: similar to ubiquitin-activating enzyme E1-like 2 n=1
           Tax=Strongylocentrotus purpuratus RepID=UPI0000E46080
          Length = 1311

 Score =  106 bits (264), Expect = 1e-21
 Identities = 60/151 (39%), Positives = 88/151 (58%), Gaps = 4/151 (2%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREA--DVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQ 241
           ++  VVL    L  Q  ++  CR     +KF++   YG++   F DFG +F V DVNGE+
Sbjct: 516 QFQCVVLTETPLGLQLKINEFCRAQTPQIKFIAADVYGLYSYCFCDFGDEFTVQDVNGEE 575

Query: 242 PRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPY 421
           P  V I+ +T ++    VV CLD+Q H  ETGD+VTF EV+G T LND +  ++K + PY
Sbjct: 576 PMQVFIADVTKDNPG--VVTCLDQQYHGLETGDYVTFKEVKGMTALNDAR-HKVKRISPY 632

Query: 422 TFALVGCREEVAAMG--AYVRGGYATQVKMP 508
            F++    E+ +  G   Y  GG A +VK+P
Sbjct: 633 KFSI----EDTSGDGFQPYETGGIAIEVKVP 659

[133][TOP]
>UniRef100_C5GMZ7 Ubiquitin-activating enzyme E1 n=2 Tax=Ajellomyces dermatitidis
           RepID=C5GMZ7_AJEDR
          Length = 1031

 Score =  106 bits (264), Expect = 1e-21
 Identities = 58/146 (39%), Positives = 84/146 (57%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           Y VVVL +  L  Q  +   C +  +  +    +G+FG IF DFG  F V D  GE+P S
Sbjct: 129 YQVVVLTSTPLRDQLAIAEYCHKNKIFVIITDTFGLFGYIFTDFGENFTVVDATGEEPTS 188

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            +++ I  E+G   +V+  DE RH     D+VTFTEV+G   LN+ + R++ + GPYTF+
Sbjct: 189 GIVAGIN-EEG---LVSASDEARHGLGEDDYVTFTEVKGMEKLNNSEPRKVDIKGPYTFS 244

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     +V+ +G Y  GG  TQVKMP
Sbjct: 245 I----GDVSGLGTYQSGGIFTQVKMP 266

[134][TOP]
>UniRef100_A6QUE9 Ubiquitin-activating enzyme E1 n=1 Tax=Ajellomyces capsulatus NAm1
           RepID=A6QUE9_AJECN
          Length = 1219

 Score =  106 bits (264), Expect = 1e-21
 Identities = 59/147 (40%), Positives = 84/147 (57%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           KY VVVL    L  Q V+   C +  +  +    +G+FG IF DFG  F V D  GE+P 
Sbjct: 415 KYQVVVLTATPLRDQLVIAEYCHKNKIFVIIADTFGLFGYIFTDFGENFTVVDATGEEPT 474

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S +++ I  E+G   +V+  DE RH     D+V FTEV+G   LN+ + R++ + GPYTF
Sbjct: 475 SGIVAGID-EEG---LVSASDEARHGLGEDDYVVFTEVKGMEKLNNSEPRKVDIKGPYTF 530

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +V+ +G Y  GG  TQVKMP
Sbjct: 531 SI----GDVSGLGTYESGGIFTQVKMP 553

[135][TOP]
>UniRef100_B9HNB1 Ubiquitin-activating enzyme E1 (Fragment) n=1 Tax=Populus
           trichocarpa RepID=B9HNB1_POPTR
          Length = 820

 Score =  105 bits (263), Expect = 1e-21
 Identities = 57/150 (38%), Positives = 91/150 (60%), Gaps = 2/150 (1%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACRE--ADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGE 238
           +K+  VV  + +       +  C +    + F+     G+FGSIF DFGP+F V DV+GE
Sbjct: 118 SKFQAVVFTDVTFEKAIEFNDYCHDHKPPISFIKAEVRGLFGSIFCDFGPEFTVFDVDGE 177

Query: 239 QPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGP 418
           +P + ++++I+  + +  +V+C+D++R +F+ GD V F+EV+G T LNDGK R+IK    
Sbjct: 178 EPHTGIVASIS--NDNPALVSCVDDERLEFQDGDLVAFSEVKGMTELNDGKPRKIKNARA 235

Query: 419 YTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           Y+F L    E+ +  G Y +GG  TQVK P
Sbjct: 236 YSFFL---EEDTSDFGIYEKGGIVTQVKEP 262

[136][TOP]
>UniRef100_O46111 Ubiquitin-activating enzyme E1 n=1 Tax=Drosophila melanogaster
           RepID=O46111_DROME
          Length = 1008

 Score =  105 bits (263), Expect = 1e-21
 Identities = 62/147 (42%), Positives = 82/147 (55%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           K+ VVVL N     Q  +     E  +  +     G+F  +F DFG  F + D +G QP 
Sbjct: 120 KFRVVVLTNSDGEEQQRIAKFGHENGIALIIAETRGLFAKVFCDFGETFTIYDPDGTQPI 179

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S MI++IT +     VV CLDE RH F  GD +TF+EVQG   LN  +  +I VLGPYTF
Sbjct: 180 STMIASITHDAQG--VVTCLDETRHGFNDGDLLTFSEVQGMQELNGCQPLKITVLGPYTF 237

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     + +  G Y+ GG ATQVKMP
Sbjct: 238 SI----GDTSKFGEYMSGGVATQVKMP 260

[137][TOP]
>UniRef100_C4QHH4 Ubiquitin-activating enzyme E1, putative n=1 Tax=Schistosoma
           mansoni RepID=C4QHH4_SCHMA
          Length = 868

 Score =  105 bits (263), Expect = 1e-21
 Identities = 61/147 (41%), Positives = 81/147 (55%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           K++VVVL   S          CR   VKF+     G+FG +F DFG  FVV D  GE P 
Sbjct: 153 KFSVVVLSQGSEDLCVEYGNICRSLGVKFVVTSTCGLFGKVFCDFGTDFVVYDPTGEVPP 212

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           SVMI  I  E     +V CL+E RH F+ GD+VTF+EV+G   LN  + R + V+GP  F
Sbjct: 213 SVMIQQI--EKSKQGLVTCLEETRHGFQDGDYVTFSEVKGMVELNGCEPRRVTVVGPDVF 270

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     + +   +Y+ GG  T VKMP
Sbjct: 271 SI----GDTSDFSSYISGGMCTLVKMP 293

[138][TOP]
>UniRef100_C0NPC9 Ubiquitin-activating enzyme E1 n=1 Tax=Ajellomyces capsulatus
           G186AR RepID=C0NPC9_AJECG
          Length = 1131

 Score =  105 bits (263), Expect = 1e-21
 Identities = 59/147 (40%), Positives = 84/147 (57%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           KY VVVL    L  Q V+   C +  +  +    +G+FG IF DFG  F V D  GE+P 
Sbjct: 228 KYQVVVLTATPLRDQLVIAEYCHKNKIFVIIADTFGLFGYIFTDFGENFTVVDATGEEPT 287

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S +++ I  E+G   +V+  DE RH     D+V FTEV+G   LN+ + R++ + GPYTF
Sbjct: 288 SGIVAGID-EEG---LVSASDEARHGLGEDDYVIFTEVKGMEKLNNSEPRKVDIKGPYTF 343

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +V+ +G Y  GG  TQVKMP
Sbjct: 344 SI----GDVSGLGTYESGGIFTQVKMP 366

[139][TOP]
>UniRef100_C5MI22 Ubiquitin-activating enzyme E1 n=1 Tax=Candida tropicalis MYA-3404
           RepID=C5MI22_CANTT
          Length = 1021

 Score =  105 bits (262), Expect = 2e-21
 Identities = 58/147 (39%), Positives = 81/147 (55%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           K+  +V  N +L  Q  ++      D+ +++    G+FG IF DFG KF V D  GE+P 
Sbjct: 122 KFKCIVSTNITLEEQVKINNITHANDIGYINADIRGLFGQIFVDFGEKFTVIDQTGEEPL 181

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
             ++S I      D  V  LD+ RH  E GD+V F E+QG   LNDG   +I+VLGPY F
Sbjct: 182 GGIVSDIE----KDGTVTMLDDNRHGLEDGDYVKFAEIQGMPKLNDGNPHKIEVLGPYAF 237

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
            +    +   + G Y+RGG  TQVK+P
Sbjct: 238 KI----KIDESYGEYIRGGLYTQVKVP 260

[140][TOP]
>UniRef100_A5DZA8 Ubiquitin-activating enzyme E1 n=1 Tax=Lodderomyces elongisporus
           RepID=A5DZA8_LODEL
          Length = 1020

 Score =  104 bits (260), Expect = 3e-21
 Identities = 58/147 (39%), Positives = 81/147 (55%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           K+  +V  N +L  Q  ++      D+ +++    G+FG IF DFG KF + D  GE+P 
Sbjct: 122 KFKCIVSTNVTLEEQVRINQITHANDIGYINADIRGLFGQIFVDFGDKFTIVDQTGEEPL 181

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S +IS I      D  V  LD+ RH  E GD V FTEV+G   LNDG   +++VLGPY F
Sbjct: 182 SGIISDID----KDGTVTMLDDSRHGLEDGDFVKFTEVEGMPKLNDGNPHKVEVLGPYAF 237

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
            +    +   + G Y +GG  TQVK+P
Sbjct: 238 KI----KLDESFGTYKKGGQYTQVKVP 260

[141][TOP]
>UniRef100_A7TIE2 Ubiquitin-activating enzyme E1 n=1 Tax=Vanderwaltozyma polyspora
           DSM 70294 RepID=A7TIE2_VANPO
          Length = 1019

 Score =  104 bits (259), Expect = 4e-21
 Identities = 53/147 (36%), Positives = 91/147 (61%), Gaps = 1/147 (0%)
 Frame = +2

Query: 71  YTVVVLVNQ-SLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           + V+V+ +  +L  +  ++  C + ++KF+S   +G+FG++F DFG +F V D  GE+PR
Sbjct: 118 FQVIVITDLLTLEDKIKMNDFCHKHNIKFISTETHGLFGNVFVDFGDEFTVIDPTGEEPR 177

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           + +IS I      +  +  LD+ RH  E G++V F+E++G   LNDG   +++VLGP+ F
Sbjct: 178 TGIISDIE----PNGTITMLDDNRHGLEDGNYVKFSEIEGLESLNDGALHKVEVLGPFAF 233

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
            +    + V  +G YV+GG  T+VK+P
Sbjct: 234 KI----DHVDNLGTYVKGGVFTEVKVP 256

[142][TOP]
>UniRef100_C4R5S2 Ubiquitin-activating enzyme E1 n=1 Tax=Pichia pastoris GS115
           RepID=C4R5S2_PICPG
          Length = 1029

 Score =  103 bits (258), Expect = 5e-21
 Identities = 58/146 (39%), Positives = 81/146 (55%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + V+V    SL  Q  ++      ++KF+S    G+FG  F DFG  F V D  GE+P+ 
Sbjct: 132 FQVIVTTETSLEKQVQINEFTHANNIKFISAATRGLFGQAFIDFGDSFTVLDQTGEEPKQ 191

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            ++S I      D  V  LD+ RHD E G +V F+EVQG   LNDG+  +IKVLGPY F 
Sbjct: 192 GIVSDIE----PDGTVTMLDDSRHDLEDGRYVKFSEVQGIERLNDGQLFKIKVLGPYAFK 247

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +    +   + G Y +GG  T+VK+P
Sbjct: 248 I----DFDNSWGTYEKGGIFTEVKVP 269

[143][TOP]
>UniRef100_Q84NQ2 Ubiquitin-activating enzyme E1 n=1 Tax=Oryza sativa Japonica Group
           RepID=Q84NQ2_ORYSJ
          Length = 1045

 Score =  103 bits (256), Expect = 9e-21
 Identities = 53/150 (35%), Positives = 87/150 (58%), Gaps = 2/150 (1%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACRE--ADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGE 238
           +K+  VV  +  L      D  C      + F+     G+FG++F DFGP+F V DV+GE
Sbjct: 145 SKFQAVVFTDIGLDKAYEFDDYCHSHCPPISFIKAEVCGLFGTVFCDFGPEFTVLDVDGE 204

Query: 239 QPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGP 418
            P + +I++I+  + +  +V+C+D++R +F+ GD V F+EV G   LNDGK R++K   P
Sbjct: 205 DPHTGIIASIS--NDNPALVSCVDDERLEFQDGDFVVFSEVHGMAELNDGKPRKVKNARP 262

Query: 419 YTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++F +    E+      Y++GG  TQ+K P
Sbjct: 263 FSFCI---EEDTTKYDMYIKGGIVTQIKEP 289

[144][TOP]
>UniRef100_B9FV11 Ubiquitin-activating enzyme E1 n=1 Tax=Oryza sativa Japonica Group
           RepID=B9FV11_ORYSJ
          Length = 1243

 Score =  103 bits (256), Expect = 9e-21
 Identities = 53/150 (35%), Positives = 87/150 (58%), Gaps = 2/150 (1%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACRE--ADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGE 238
           +K+  VV  +  L      D  C      + F+     G+FG++F DFGP+F V DV+GE
Sbjct: 158 SKFQAVVFTDIGLDKAYEFDDYCHSHCPPISFIKAEVCGLFGTVFCDFGPEFTVLDVDGE 217

Query: 239 QPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGP 418
            P + +I++I+  + +  +V+C+D++R +F+ GD V F+EV G   LNDGK R++K   P
Sbjct: 218 DPHTGIIASIS--NDNPALVSCVDDERLEFQDGDFVVFSEVHGMAELNDGKPRKVKNARP 275

Query: 419 YTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++F +    E+      Y++GG  TQ+K P
Sbjct: 276 FSFCI---EEDTTKYDMYIKGGIVTQIKEP 302

[145][TOP]
>UniRef100_B8B6A7 Ubiquitin-activating enzyme E1 n=1 Tax=Oryza sativa Indica Group
           RepID=B8B6A7_ORYSI
          Length = 1058

 Score =  103 bits (256), Expect = 9e-21
 Identities = 53/150 (35%), Positives = 87/150 (58%), Gaps = 2/150 (1%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACRE--ADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGE 238
           +K+  VV  +  L      D  C      + F+     G+FG++F DFGP+F V DV+GE
Sbjct: 158 SKFLAVVFTDIGLDKAYEFDDYCHSHCPPISFIKAEVCGLFGTVFCDFGPEFTVLDVDGE 217

Query: 239 QPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGP 418
            P + +I++I+  + +  +V+C+D++R +F+ GD V F+EV G   LNDGK R++K   P
Sbjct: 218 DPHTGIIASIS--NDNPALVSCVDDERLEFQDGDFVVFSEVHGMAELNDGKPRKVKNARP 275

Query: 419 YTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++F +    E+      Y++GG  TQ+K P
Sbjct: 276 FSFCI---EEDTTKYDMYIKGGIVTQIKEP 302

[146][TOP]
>UniRef100_Q0UI57 Ubiquitin-activating enzyme E1 n=1 Tax=Phaeosphaeria nodorum
           RepID=Q0UI57_PHANO
          Length = 1056

 Score =  103 bits (256), Expect = 9e-21
 Identities = 58/147 (39%), Positives = 84/147 (57%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           ++ V+VL + +L  Q  +   C +  +  +    YG+FG+IF DFG  F + D  GE   
Sbjct: 162 QFQVIVLTDTALDDQIKIADYCHDNGIYIVITDTYGLFGTIFTDFGKNFTIGDPTGENVT 221

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           + +I+ I  E G   +V+ LDE RH  E GD VTF+EV+G   LN    R+I+V GPYTF
Sbjct: 222 NGIIAGID-ESG---LVSALDETRHGLEDGDWVTFSEVKGMEALNGCAPRKIEVKGPYTF 277

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     +V+ +G Y  GG   QVKMP
Sbjct: 278 SI----GDVSGLGTYQSGGQYIQVKMP 300

[147][TOP]
>UniRef100_Q5JRR9 Ubiquitin-like modifier activating enzyme 1 (Fragment) n=1 Tax=Homo
           sapiens RepID=Q5JRR9_HUMAN
          Length = 271

 Score =  102 bits (253), Expect = 2e-20
 Identities = 53/115 (46%), Positives = 70/115 (60%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL N  L  Q  V   C    +K +     G+FG +F DFG + +++D NGEQP S
Sbjct: 159 FQVVVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLS 218

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLG 415
            M+S +T ++    VV CLDE RH FE+GD V+F+EVQG   LN  +  EIKVLG
Sbjct: 219 AMVSMVTKDNPG--VVTCLDEARHGFESGDFVSFSEVQGMVELNGNQPMEIKVLG 271

[148][TOP]
>UniRef100_Q752Y8 Ubiquitin-activating enzyme E1 n=1 Tax=Eremothecium gossypii
           RepID=Q752Y8_ASHGO
          Length = 1013

 Score =  101 bits (251), Expect = 3e-20
 Identities = 59/148 (39%), Positives = 81/148 (54%), Gaps = 1/148 (0%)
 Frame = +2

Query: 68  KYTVVVLVNQ-SLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           ++ V+V  N   LA +  ++       V+F++    G+FG IF D G  F V D  GE P
Sbjct: 114 EFQVIVATNTVPLAERLRLNRYAHAHGVRFIAAETRGLFGQIFVDLGEDFTVIDSTGEDP 173

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
           +S ++S I      D  V  LD+ RH+ E GD+V FTEV G  GLNDG   +++VLGP+ 
Sbjct: 174 KSGIVSDIEA----DGTVTMLDDSRHNLEDGDYVRFTEVDGLEGLNDGTPYKVEVLGPFA 229

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F +      V   G Y +GG  TQVKMP
Sbjct: 230 FRI----GSVEKFGVYKKGGIFTQVKMP 253

[149][TOP]
>UniRef100_UPI0000E20401 PREDICTED: ubiquitin-activating enzyme E1-like 2 n=1 Tax=Pan
           troglodytes RepID=UPI0000E20401
          Length = 1031

 Score =  100 bits (250), Expect = 4e-20
 Identities = 55/149 (36%), Positives = 82/149 (55%), Gaps = 2/149 (1%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREA--DVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQ 241
           KY  VVL    L  Q  ++  CR     +KF+S   +G++  +F DFG +F V D  GE+
Sbjct: 132 KYQCVVLTEMKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGDEFEVLDTTGEE 191

Query: 242 PRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPY 421
           P+ + IS IT    +  +V CL+   H  ETG  +TF E+ G TGLN G  ++I V+ P+
Sbjct: 192 PKEIFISNIT--QANPGIVTCLENHPHKLETGQFLTFREINGMTGLN-GSIQQITVISPF 248

Query: 422 TFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +F++     +   +  Y+ GG A QVK P
Sbjct: 249 SFSI----GDTTELEPYLHGGIAVQVKTP 273

[150][TOP]
>UniRef100_UPI00005A2AD3 PREDICTED: similar to ubiquitin-activating enzyme E1 (A1S9T and
           BN75 temperature sensitivity complementing) n=1
           Tax=Canis lupus familiaris RepID=UPI00005A2AD3
          Length = 1052

 Score =  100 bits (250), Expect = 4e-20
 Identities = 56/149 (37%), Positives = 83/149 (55%), Gaps = 2/149 (1%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREA--DVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQ 241
           KY  VVL    L  Q  ++  C      +KF+S   +G++  +F DFG +F VSD  GE+
Sbjct: 153 KYQCVVLTEIKLPLQKKINNFCHSQCPPIKFISTDIHGIWSRLFCDFGDEFEVSDTTGEE 212

Query: 242 PRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPY 421
           P+ + IS IT    +  +V CL+   H  ETG  +TF EV G TGLN G +++I V+ P+
Sbjct: 213 PKEIFISNIT--QANPGIVTCLENHPHKLETGQFLTFREVNGMTGLN-GSTQQITVVSPF 269

Query: 422 TFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +F++     +   +  Y+ GG A QVK P
Sbjct: 270 SFSI----GDTTELEPYLHGGIAVQVKTP 294

[151][TOP]
>UniRef100_UPI000036CD33 PREDICTED: ubiquitin-activating enzyme E1-like 2 n=1 Tax=Pan
           troglodytes RepID=UPI000036CD33
          Length = 1052

 Score =  100 bits (250), Expect = 4e-20
 Identities = 55/149 (36%), Positives = 82/149 (55%), Gaps = 2/149 (1%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREA--DVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQ 241
           KY  VVL    L  Q  ++  CR     +KF+S   +G++  +F DFG +F V D  GE+
Sbjct: 153 KYQCVVLTEMKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGDEFEVLDTTGEE 212

Query: 242 PRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPY 421
           P+ + IS IT    +  +V CL+   H  ETG  +TF E+ G TGLN G  ++I V+ P+
Sbjct: 213 PKEIFISNIT--QANPGIVTCLENHPHKLETGQFLTFREINGMTGLN-GSIQQITVISPF 269

Query: 422 TFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +F++     +   +  Y+ GG A QVK P
Sbjct: 270 SFSI----GDTTELEPYLHGGIAVQVKTP 294

[152][TOP]
>UniRef100_UPI0000EB23F8 Ubiquitin-activating enzyme E1-like protein 2 (Monocyte protein 4)
           (MOP-4). n=1 Tax=Canis lupus familiaris
           RepID=UPI0000EB23F8
          Length = 1054

 Score =  100 bits (250), Expect = 4e-20
 Identities = 56/149 (37%), Positives = 83/149 (55%), Gaps = 2/149 (1%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREA--DVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQ 241
           KY  VVL    L  Q  ++  C      +KF+S   +G++  +F DFG +F VSD  GE+
Sbjct: 153 KYQCVVLTEIKLPLQKKINNFCHSQCPPIKFISTDIHGIWSRLFCDFGDEFEVSDTTGEE 212

Query: 242 PRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPY 421
           P+ + IS IT    +  +V CL+   H  ETG  +TF EV G TGLN G +++I V+ P+
Sbjct: 213 PKEIFISNIT--QANPGIVTCLENHPHKLETGQFLTFREVNGMTGLN-GSTQQITVVSPF 269

Query: 422 TFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +F++     +   +  Y+ GG A QVK P
Sbjct: 270 SFSI----GDTTELEPYLHGGIAVQVKTP 294

[153][TOP]
>UniRef100_B9HNB0 Ubiquitin-activating enzyme E1 n=1 Tax=Populus trichocarpa
           RepID=B9HNB0_POPTR
          Length = 1018

 Score =  100 bits (250), Expect = 4e-20
 Identities = 56/150 (37%), Positives = 88/150 (58%), Gaps = 2/150 (1%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGE 238
           +K+  VV  + +L      +  C   +  + F+     G+FGS+F DFGP+F V DV+GE
Sbjct: 118 SKFQAVVFTDLNLDKAIEFNDYCHNHKPPISFIKAEVRGLFGSVFCDFGPEFTVFDVDGE 177

Query: 239 QPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGP 418
              + +I++I+  + +  +V+ +D++R +F+ GD V F+EV+G T LNDGK R+IK   P
Sbjct: 178 DAHTGIIASIS--NDNPALVSFVDDERLEFQDGDLVVFSEVKGMTELNDGKPRKIKNTRP 235

Query: 419 YTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           Y+F L    E+      Y +GG  TQVK P
Sbjct: 236 YSFTL---EEDTTNFATYEKGGIVTQVKQP 262

[154][TOP]
>UniRef100_B9HNA9 Ubiquitin-activating enzyme E1 n=1 Tax=Populus trichocarpa
           RepID=B9HNA9_POPTR
          Length = 907

 Score =  100 bits (250), Expect = 4e-20
 Identities = 56/150 (37%), Positives = 88/150 (58%), Gaps = 2/150 (1%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGE 238
           +K+  VV  + +L      +  C   +  + F+     G+FGS+F DFGP+F V DV+GE
Sbjct: 197 SKFQAVVFTDLNLDKAIEFNDYCHNHKPPISFIKAEVRGLFGSVFCDFGPEFTVFDVDGE 256

Query: 239 QPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGP 418
              + +I++I+  + +  +V+ +D++R +F+ GD V F+EV+G T LNDGK R+IK   P
Sbjct: 257 DAHTGIIASIS--NDNPALVSFVDDERLEFQDGDLVVFSEVKGMTELNDGKPRKIKNTRP 314

Query: 419 YTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           Y+F L    E+      Y +GG  TQVK P
Sbjct: 315 YSFTL---EEDTTNFATYEKGGIVTQVKQP 341

[155][TOP]
>UniRef100_C5DZ85 Ubiquitin-activating enzyme E1 n=1 Tax=Zygosaccharomyces rouxii CBS
           732 RepID=C5DZ85_ZYGRC
          Length = 1011

 Score =  100 bits (250), Expect = 4e-20
 Identities = 56/144 (38%), Positives = 81/144 (56%)
 Frame = +2

Query: 77  VVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRSVM 256
           VV     SL  +  ++  C  A + F+S    G+FG++F D G +F V D  GE+PRS +
Sbjct: 118 VVATETVSLQEKVNLNNLCHAAGIGFISTETRGLFGNVFVDLGDEFTVLDPTGEEPRSGI 177

Query: 257 ISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFALV 436
           +S I      D  V  LDE RH  E G++V F+EV+G   LNDG   +++VLGP+ F + 
Sbjct: 178 VSDIE----PDGTVTMLDENRHGLEDGNYVKFSEVEGLEKLNDGSLFKVEVLGPFAFRI- 232

Query: 437 GCREEVAAMGAYVRGGYATQVKMP 508
                V+  G Y++GG  T+VK P
Sbjct: 233 ---GPVSQYGKYIKGGIFTEVKQP 253

[156][TOP]
>UniRef100_Q8C7R4 Ubiquitin-like modifier-activating enzyme 6 n=2 Tax=Mus musculus
           RepID=UBA6_MOUSE
          Length = 1053

 Score =  100 bits (250), Expect = 4e-20
 Identities = 55/149 (36%), Positives = 82/149 (55%), Gaps = 2/149 (1%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACRE--ADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQ 241
           KY  VVL    L  Q  ++  C      +KF+S   +G++  +F DFG +F VSD  GE+
Sbjct: 153 KYQCVVLTEIKLTLQKKINNFCHSHCPPIKFISADVHGIWSRLFCDFGDEFEVSDTTGEE 212

Query: 242 PRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPY 421
           P+ + IS IT    +  +V CL+   H  ETG  +TF E+ G TGLN G  ++I V+ P+
Sbjct: 213 PKEIFISNIT--QANPGIVTCLESHPHKLETGQFLTFREIHGMTGLN-GSVQQITVISPF 269

Query: 422 TFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +F++     +   +  Y+ GG A QVK P
Sbjct: 270 SFSI----GDTTKLDPYLHGGIAVQVKTP 294

[157][TOP]
>UniRef100_A0AVT1-3 Isoform 3 of Ubiquitin-like modifier-activating enzyme 6 n=1
           Tax=Homo sapiens RepID=A0AVT1-3
          Length = 389

 Score =  100 bits (250), Expect = 4e-20
 Identities = 55/149 (36%), Positives = 82/149 (55%), Gaps = 2/149 (1%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREA--DVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQ 241
           KY  VVL    L  Q  ++  CR     +KF+S   +G++  +F DFG +F V D  GE+
Sbjct: 153 KYQCVVLTEMKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGDEFEVLDTTGEE 212

Query: 242 PRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPY 421
           P+ + IS IT    +  +V CL+   H  ETG  +TF E+ G TGLN G  ++I V+ P+
Sbjct: 213 PKEIFISNIT--QANPGIVTCLENHPHKLETGQFLTFREINGMTGLN-GSIQQITVISPF 269

Query: 422 TFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +F++     +   +  Y+ GG A QVK P
Sbjct: 270 SFSI----GDTTELEPYLHGGIAVQVKTP 294

[158][TOP]
>UniRef100_A0AVT1-4 Isoform 4 of Ubiquitin-like modifier-activating enzyme 6 n=1
           Tax=Homo sapiens RepID=A0AVT1-4
          Length = 340

 Score =  100 bits (250), Expect = 4e-20
 Identities = 55/149 (36%), Positives = 82/149 (55%), Gaps = 2/149 (1%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREA--DVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQ 241
           KY  VVL    L  Q  ++  CR     +KF+S   +G++  +F DFG +F V D  GE+
Sbjct: 153 KYQCVVLTEMKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGDEFEVLDTTGEE 212

Query: 242 PRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPY 421
           P+ + IS IT    +  +V CL+   H  ETG  +TF E+ G TGLN G  ++I V+ P+
Sbjct: 213 PKEIFISNIT--QANPGIVTCLENHPHKLETGQFLTFREINGMTGLN-GSIQQITVISPF 269

Query: 422 TFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +F++     +   +  Y+ GG A QVK P
Sbjct: 270 SFSI----GDTTELEPYLHGGIAVQVKTP 294

[159][TOP]
>UniRef100_A0AVT1 Ubiquitin-like modifier-activating enzyme 6 n=1 Tax=Homo sapiens
           RepID=UBA6_HUMAN
          Length = 1052

 Score =  100 bits (250), Expect = 4e-20
 Identities = 55/149 (36%), Positives = 82/149 (55%), Gaps = 2/149 (1%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREA--DVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQ 241
           KY  VVL    L  Q  ++  CR     +KF+S   +G++  +F DFG +F V D  GE+
Sbjct: 153 KYQCVVLTEMKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGDEFEVLDTTGEE 212

Query: 242 PRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPY 421
           P+ + IS IT    +  +V CL+   H  ETG  +TF E+ G TGLN G  ++I V+ P+
Sbjct: 213 PKEIFISNIT--QANPGIVTCLENHPHKLETGQFLTFREINGMTGLN-GSIQQITVISPF 269

Query: 422 TFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +F++     +   +  Y+ GG A QVK P
Sbjct: 270 SFSI----GDTTELEPYLHGGIAVQVKTP 294

[160][TOP]
>UniRef100_B9WEN1 Ubiquitin-activating enzyme E1 n=1 Tax=Candida dubliniensis CD36
           RepID=B9WEN1_CANDC
          Length = 1021

 Score =  100 bits (249), Expect = 6e-20
 Identities = 55/147 (37%), Positives = 81/147 (55%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           K+  +V  N SL  Q  ++      ++ +++    G+FG IF DFG KF V D  GE+P 
Sbjct: 122 KFKCIVSTNISLEEQVKINNITHANNIGYINADIKGLFGQIFVDFGDKFTVIDQTGEEPL 181

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S ++S I         V  LD+ RH  + GD+V F E++G   LNDG   +++VLGPY F
Sbjct: 182 SGIVSDIEKNG----TVTMLDDNRHGLQDGDYVKFAEIEGMPKLNDGNPHKVEVLGPYAF 237

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
            +    +   + G YV+GG  TQVK+P
Sbjct: 238 KI----KIDDSYGEYVKGGLYTQVKVP 260

[161][TOP]
>UniRef100_UPI000179EC47 UPI000179EC47 related cluster n=1 Tax=Bos taurus
           RepID=UPI000179EC47
          Length = 1057

 Score =  100 bits (248), Expect = 7e-20
 Identities = 54/147 (36%), Positives = 83/147 (56%), Gaps = 2/147 (1%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREA--DVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQ 241
           KY  VVL    L+ Q  ++  CR     +KF+S   +G++  +F DFG +F V D  GE+
Sbjct: 153 KYQCVVLTEMKLSVQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGDEFEVLDTTGEE 212

Query: 242 PRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPY 421
           P+ + IS IT    +  +V CL+   H  ETG  +TF E+ G TGLN G +++I V+ P+
Sbjct: 213 PKEIFISDIT--QANPGIVTCLENHPHKLETGQFLTFREINGMTGLN-GSTQQITVVSPF 269

Query: 422 TFALVGCREEVAAMGAYVRGGYATQVK 502
           +F++     +   +  Y+ GG A QVK
Sbjct: 270 SFSI----GDTTELEPYLHGGIAIQVK 292

[162][TOP]
>UniRef100_A4FV03 UBA6 protein n=1 Tax=Bos taurus RepID=A4FV03_BOVIN
          Length = 1057

 Score =  100 bits (248), Expect = 7e-20
 Identities = 54/147 (36%), Positives = 83/147 (56%), Gaps = 2/147 (1%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREA--DVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQ 241
           KY  VVL    L+ Q  ++  CR     +KF+S   +G++  +F DFG +F V D  GE+
Sbjct: 153 KYQCVVLTEMKLSVQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGDEFEVLDTTGEE 212

Query: 242 PRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPY 421
           P+ + IS IT    +  +V CL+   H  ETG  +TF E+ G TGLN G +++I V+ P+
Sbjct: 213 PKEIFISDIT--QANPGIVTCLENHPHKLETGQFLTFREINGMTGLN-GSTQQITVVSPF 269

Query: 422 TFALVGCREEVAAMGAYVRGGYATQVK 502
           +F++     +   +  Y+ GG A QVK
Sbjct: 270 SFSI----GDTTELEPYLHGGIAIQVK 292

[163][TOP]
>UniRef100_UPI00001D0B98 ubiquitin-like modifier activating enzyme 6 n=1 Tax=Rattus
           norvegicus RepID=UPI00001D0B98
          Length = 1053

 Score = 99.8 bits (247), Expect = 1e-19
 Identities = 54/149 (36%), Positives = 81/149 (54%), Gaps = 2/149 (1%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACRE--ADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQ 241
           KY  VVL    L  Q  ++  C      +KF+S   +G++  +F DFG +F VSD  GE+
Sbjct: 153 KYQCVVLTETKLTLQKKINNFCHSHCPPIKFISTDVHGIWSRLFCDFGDEFEVSDTTGEE 212

Query: 242 PRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPY 421
           P+ + IS IT    +  +V CL+   H  ETG  +TF E+ G  GLN G  ++I V+ P+
Sbjct: 213 PKEIFISNIT--QANPGIVTCLENHPHKLETGQFLTFREINGMAGLN-GSVQQITVISPF 269

Query: 422 TFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +F++     +   +  Y+ GG A QVK P
Sbjct: 270 SFSI----GDTTELDPYLHGGIAVQVKTP 294

[164][TOP]
>UniRef100_Q5JRS0 Ubiquitin-like modifier activating enzyme 1 (Fragment) n=1 Tax=Homo
           sapiens RepID=Q5JRS0_HUMAN
          Length = 284

 Score = 99.8 bits (247), Expect = 1e-19
 Identities = 52/114 (45%), Positives = 69/114 (60%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL N  L  Q  V   C    +K +     G+FG +F DFG + +++D NGEQP S
Sbjct: 173 FQVVVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLS 232

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVL 412
            M+S +T ++    VV CLDE RH FE+GD V+F+EVQG   LN  +  EIKVL
Sbjct: 233 AMVSMVTKDNPG--VVTCLDEARHGFESGDFVSFSEVQGMVELNGNQPMEIKVL 284

[165][TOP]
>UniRef100_Q5A2X3 Ubiquitin-activating enzyme E1 n=1 Tax=Candida albicans
           RepID=Q5A2X3_CANAL
          Length = 1021

 Score = 99.8 bits (247), Expect = 1e-19
 Identities = 55/147 (37%), Positives = 81/147 (55%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           K+  +V  N SL  Q  ++      ++ +++    G+FG IF DFG KF V D  GE+P 
Sbjct: 122 KFKCIVSTNISLEEQVKINNITHANNIGYINADIKGLFGQIFVDFGDKFTVIDQTGEEPL 181

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           S ++S I         V  LD+ RH  + GD+V F EV+G   LN+G   +++VLGPY F
Sbjct: 182 SGIVSDIEKNG----TVTMLDDNRHGLQDGDYVKFAEVEGMPKLNEGNPHKVEVLGPYAF 237

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
            +    +   + G YV+GG  TQVK+P
Sbjct: 238 KI----KIDESYGEYVKGGLYTQVKVP 260

[166][TOP]
>UniRef100_B6JWS7 Ubiquitin-activating enzyme E1 n=1 Tax=Schizosaccharomyces
           japonicus yFS275 RepID=B6JWS7_SCHJY
          Length = 1010

 Score = 99.4 bits (246), Expect = 1e-19
 Identities = 58/158 (36%), Positives = 87/158 (55%)
 Frame = +2

Query: 35  SVADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKF 214
           ++ D        +  +V+   +L  Q  ++    + D+ F+S  A G+FG IF DFG  F
Sbjct: 111 AITDISLETLKNFQCIVVTETTLTKQIEINDFTHQNDIAFISTDARGLFGYIFCDFGKSF 170

Query: 215 VVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKS 394
           V ++ +G +P + +I+ I  E G   +V  L+E RH  E GD+V F+EV+G   LN  + 
Sbjct: 171 VCTNTDGNEPLTGLIAGID-ETG---LVTTLEETRHGLEDGDYVRFSEVKGMDALNQSQP 226

Query: 395 REIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
            ++ V GPYTF+ VG  E    MG Y+ GG   QVKMP
Sbjct: 227 LKVSVKGPYTFS-VGPLEN---MGTYISGGSFVQVKMP 260

[167][TOP]
>UniRef100_A8Q6K8 Ubiquitin-activating enzyme E1 n=1 Tax=Malassezia globosa CBS 7966
           RepID=A8Q6K8_MALGO
          Length = 1021

 Score = 99.4 bits (246), Expect = 1e-19
 Identities = 54/146 (36%), Positives = 81/146 (55%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVV+ +  L+ Q  V+     +   F+S    G+FG++F D G  F   D NGE P  
Sbjct: 120 FKVVVMTHALLSEQLRVNDMTHGSGTHFLSADVRGLFGTVFADLGTNFTCKDTNGEPPMD 179

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
            ++ ++T +   + +V  +DE+RH  + GD VTF+EVQG T LN  + R + V GPYTF 
Sbjct: 180 GIVVSVTQDK--EGLVTTIDEKRHGLQDGDFVTFSEVQGMTELNGIEPRRVTVKGPYTFT 237

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     + ++ G Y  GG   QVKMP
Sbjct: 238 I----GDTSSFGQYKGGGLFKQVKMP 259

[168][TOP]
>UniRef100_C8ZBX0 Uba1p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8ZBX0_YEAST
          Length = 1024

 Score = 99.0 bits (245), Expect = 2e-19
 Identities = 56/155 (36%), Positives = 84/155 (54%)
 Frame = +2

Query: 44  DAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVS 223
           D V  ++    VV     SL  +  ++  C  + ++F+S    G+FG+ F D G +F V 
Sbjct: 115 DDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVL 174

Query: 224 DVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREI 403
           D  GE+PR+ M+S I      D  V  LD+ RH  E G+ V F+EV+G   LNDG   ++
Sbjct: 175 DPTGEEPRTGMVSDIE----PDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKV 230

Query: 404 KVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +VLGP+ F +   +E     G Y +GG  T+VK+P
Sbjct: 231 EVLGPFAFRIGSVKE----FGEYKKGGIFTEVKVP 261

[169][TOP]
>UniRef100_B3LQP9 Ubiquitin-activating enzyme E1 n=1 Tax=Saccharomyces cerevisiae
           RM11-1a RepID=B3LQP9_YEAS1
          Length = 1024

 Score = 99.0 bits (245), Expect = 2e-19
 Identities = 56/155 (36%), Positives = 84/155 (54%)
 Frame = +2

Query: 44  DAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVS 223
           D V  ++    VV     SL  +  ++  C  + ++F+S    G+FG+ F D G +F V 
Sbjct: 115 DDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVL 174

Query: 224 DVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREI 403
           D  GE+PR+ M+S I      D  V  LD+ RH  E G+ V F+EV+G   LNDG   ++
Sbjct: 175 DPTGEEPRTGMVSDIE----PDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKV 230

Query: 404 KVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +VLGP+ F +   +E     G Y +GG  T+VK+P
Sbjct: 231 EVLGPFAFRIGSVKE----FGEYKKGGIFTEVKVP 261

[170][TOP]
>UniRef100_A7A079 Ubiquitin-activating enzyme E1 n=1 Tax=Saccharomyces cerevisiae
           YJM789 RepID=A7A079_YEAS7
          Length = 1024

 Score = 99.0 bits (245), Expect = 2e-19
 Identities = 56/155 (36%), Positives = 84/155 (54%)
 Frame = +2

Query: 44  DAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVS 223
           D V  ++    VV     SL  +  ++  C  + ++F+S    G+FG+ F D G +F V 
Sbjct: 115 DDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVL 174

Query: 224 DVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREI 403
           D  GE+PR+ M+S I      D  V  LD+ RH  E G+ V F+EV+G   LNDG   ++
Sbjct: 175 DPTGEEPRTGMVSDIE----PDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKV 230

Query: 404 KVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +VLGP+ F +   +E     G Y +GG  T+VK+P
Sbjct: 231 EVLGPFAFRIGSVKE----FGEYKKGGIFTEVKVP 261

[171][TOP]
>UniRef100_C7GJ03 Uba1p n=1 Tax=Saccharomyces cerevisiae JAY291 RepID=C7GJ03_YEAS2
          Length = 1024

 Score = 98.6 bits (244), Expect = 2e-19
 Identities = 55/155 (35%), Positives = 84/155 (54%)
 Frame = +2

Query: 44  DAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVS 223
           D +  ++    VV     SL  +  ++  C  + ++F+S    G+FG+ F D G +F V 
Sbjct: 115 DDITQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVL 174

Query: 224 DVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREI 403
           D  GE+PR+ M+S I      D  V  LD+ RH  E G+ V F+EV+G   LNDG   ++
Sbjct: 175 DPTGEEPRTGMVSDIE----PDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKV 230

Query: 404 KVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +VLGP+ F +   +E     G Y +GG  T+VK+P
Sbjct: 231 EVLGPFAFRIGSVKE----FGEYKKGGIFTEVKVP 261

[172][TOP]
>UniRef100_C4Y7L0 Ubiquitin-activating enzyme E1 n=1 Tax=Clavispora lusitaniae ATCC
           42720 RepID=C4Y7L0_CLAL4
          Length = 1012

 Score = 98.6 bits (244), Expect = 2e-19
 Identities = 59/157 (37%), Positives = 85/157 (54%)
 Frame = +2

Query: 38  VADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFV 217
           +++   A  A++  VV  N SL  Q  ++      +V F++    G+FG +F DFG  F 
Sbjct: 108 LSELADADVARFQCVVATNASLEQQVRLNDVTHANNVGFIATDVRGLFGQLFVDFGD-FT 166

Query: 218 VSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSR 397
           V D  GE+P S ++S I      +  V  LD+ RH  + GD+V F+EV+G   LNDG  R
Sbjct: 167 VIDQTGEEPLSGIVSDIE----PNGTVTMLDDNRHGLQDGDYVRFSEVEGMPKLNDGTPR 222

Query: 398 EIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
            ++VLGPY F +        + G YV+GG   QVKMP
Sbjct: 223 RVEVLGPYAFKI----SIDDSFGTYVKGGLYQQVKMP 255

[173][TOP]
>UniRef100_P22515 Ubiquitin-activating enzyme E1 1 n=1 Tax=Saccharomyces cerevisiae
           RepID=UBA1_YEAST
          Length = 1024

 Score = 98.6 bits (244), Expect = 2e-19
 Identities = 56/155 (36%), Positives = 84/155 (54%)
 Frame = +2

Query: 44  DAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVS 223
           D V  ++    VV     SL  +  ++  C  + ++F+S    G+FG+ F D G +F V 
Sbjct: 115 DDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVL 174

Query: 224 DVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREI 403
           D  GE+PR+ M+S I      D  V  LD+ RH  E G+ V F+EV+G   LNDG   ++
Sbjct: 175 DPTGEEPRTGMVSDIE----PDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKV 230

Query: 404 KVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +VLGP+ F +   +E     G Y +GG  T+VK+P
Sbjct: 231 EVLGPFAFRIGSVKE----YGEYKKGGIFTEVKVP 261

[174][TOP]
>UniRef100_UPI0000F2D78A PREDICTED: similar to Ubiquitin-activating enzyme E1-like 2 n=1
           Tax=Monodelphis domestica RepID=UPI0000F2D78A
          Length = 1057

 Score = 98.2 bits (243), Expect = 3e-19
 Identities = 53/147 (36%), Positives = 84/147 (57%), Gaps = 2/147 (1%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAAC--READVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQ 241
           +Y  VVL    L  Q +++  C  +   +KF+S   +G++  +F DFG +F V D +GE+
Sbjct: 158 QYQCVVLTEIRLPLQKMINEFCHAQHPPIKFVSADVFGIWSRLFCDFGDEFEVLDTSGEE 217

Query: 242 PRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPY 421
           P+ + IS IT    +  +V CL+   H  ETG+ VTF E+ G  GLN G +++I V+ P+
Sbjct: 218 PKEIFISNIT--QANPGIVTCLENHPHKLETGNFVTFREINGMAGLN-GSTKQITVVSPF 274

Query: 422 TFALVGCREEVAAMGAYVRGGYATQVK 502
           +F++     +   M  Y+ GG A QVK
Sbjct: 275 SFSI----GDTTEMEPYLHGGIAVQVK 297

[175][TOP]
>UniRef100_B8BYU7 Ubiquitin-activating enzyme E1 n=1 Tax=Thalassiosira pseudonana
           CCMP1335 RepID=B8BYU7_THAPS
          Length = 1015

 Score = 98.2 bits (243), Expect = 3e-19
 Identities = 59/148 (39%), Positives = 83/148 (56%), Gaps = 2/148 (1%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVV +    +    ++  CR ++  F++    GVFG +F DFG  FV+SD +GE P +
Sbjct: 100 FCVVVTIPLPTSLLCAINEKCRASNACFINTLTTGVFGYVFCDFGTSFVISDKDGENPAT 159

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATG-LNDGKSR-EIKVLGPYT 424
             +  I L     +V    D+ RH  ETGDHVTF++V+G  G LND K+  E++V GP+T
Sbjct: 160 SQVENI-LTSNPALVKVLEDQGRHGLETGDHVTFSKVKGLDGMLNDSKTTFEVRVTGPFT 218

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F LVG      +  A    GY TQVK P
Sbjct: 219 FELVGVDSSQCSEPA--TQGYITQVKTP 244

[176][TOP]
>UniRef100_Q6FNF6 Ubiquitin-activating enzyme E1 n=1 Tax=Candida glabrata
           RepID=Q6FNF6_CANGA
          Length = 1014

 Score = 97.4 bits (241), Expect = 5e-19
 Identities = 54/144 (37%), Positives = 81/144 (56%)
 Frame = +2

Query: 77  VVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRSVM 256
           VV     SL  +  ++  C  + VKF++    G+FG  F D G +F V D  GE+PR+ +
Sbjct: 119 VVATETVSLEDKIKMNNICHNSGVKFIATETRGLFGQAFVDLGDEFSVIDQTGEEPRTGI 178

Query: 257 ISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFALV 436
           +S I      D  V  LD+ RH  E G++V F+EVQG   LNDG   +++VLGP+ F + 
Sbjct: 179 VSDIE----PDGTVTMLDDSRHGLEDGNYVKFSEVQGLEKLNDGTLYKVEVLGPFAFRIG 234

Query: 437 GCREEVAAMGAYVRGGYATQVKMP 508
             ++    +G Y +GG  T+VK+P
Sbjct: 235 SVKD----LGEYKKGGIFTEVKVP 254

[177][TOP]
>UniRef100_UPI0000ECC5B5 Ubiquitin-activating enzyme E1-like protein 2 (Monocyte protein 4)
           (MOP-4). n=2 Tax=Gallus gallus RepID=UPI0000ECC5B5
          Length = 1029

 Score = 96.7 bits (239), Expect = 8e-19
 Identities = 54/149 (36%), Positives = 83/149 (55%), Gaps = 2/149 (1%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAAC--READVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQ 241
           +Y  V+L   +L+ Q  ++  C  ++  +KF+S   YG+   +F DFG +F V D  GE+
Sbjct: 130 QYQCVILTEVNLSLQKKINDFCHAQQPPIKFISADVYGICSRLFCDFGDEFEVLDTTGEE 189

Query: 242 PRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPY 421
           P+ + IS IT    +  +V CL+   H  ETG  +TF EV G + LN G + +I V+ PY
Sbjct: 190 PKEIFISNIT--QSNPGIVTCLENHPHRLETGQFLTFREVNGMSCLN-GSTHQITVVSPY 246

Query: 422 TFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +F++       + M  Y+ GG A QVK P
Sbjct: 247 SFSI----GNTSDMEPYLHGGIAVQVKTP 271

[178][TOP]
>UniRef100_A8J1C1 Ubiquitin-activating enzyme E1 n=1 Tax=Chlamydomonas reinhardtii
           RepID=A8J1C1_CHLRE
          Length = 1061

 Score = 96.3 bits (238), Expect = 1e-18
 Identities = 53/157 (33%), Positives = 85/157 (54%)
 Frame = +2

Query: 32  ASVADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPK 211
           A+  +   A   ++ VVV     LA    +DA C  A   F+     GVF  +F DFGP 
Sbjct: 132 AASGELTDAFVRQFQVVVATTAPLAEAKRLDALCHAAGTAFIWAQTRGVFARVFTDFGPA 191

Query: 212 FVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGK 391
           F V DVNGE+P S ++++++   G   +V C++++R +F+ G+ V+F+EV G   LN   
Sbjct: 192 FTVYDVNGEEPHSGIVASVS--SGSPAMVTCVEDERLEFQDGELVSFSEVVGMDKLNTHG 249

Query: 392 SREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVK 502
             ++K    ++F +     + ++ G YVRGG   QVK
Sbjct: 250 PFKVKNCKAHSFEI---EADTSSWGEYVRGGIVVQVK 283

[179][TOP]
>UniRef100_UPI000155CA0E PREDICTED: hypothetical protein n=1 Tax=Ornithorhynchus anatinus
           RepID=UPI000155CA0E
          Length = 1252

 Score = 95.9 bits (237), Expect = 1e-18
 Identities = 51/147 (34%), Positives = 83/147 (56%), Gaps = 2/147 (1%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAAC--READVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQ 241
           +Y  VVL    L+ Q  ++  C  ++  +KF+S   +G++  +F DFG +F V D  GE+
Sbjct: 306 QYQCVVLTEMRLSLQKKINDFCHAQQPPIKFISADVHGIWSRLFCDFGDEFEVLDSTGEE 365

Query: 242 PRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPY 421
           P+ + +S +T    +  +V CL+   H  ETG  VTF E+ G T LN G +++I V+ P+
Sbjct: 366 PKEIFVSNVT--QANPGIVTCLENHPHKLETGQFVTFREINGMTALN-GSTQQITVVSPF 422

Query: 422 TFALVGCREEVAAMGAYVRGGYATQVK 502
           +F++     +   M  Y+ GG A QVK
Sbjct: 423 SFSI----GDTTEMAPYLYGGIAVQVK 445

[180][TOP]
>UniRef100_Q6CV73 Ubiquitin-activating enzyme E1 n=1 Tax=Kluyveromyces lactis
           RepID=Q6CV73_KLULA
          Length = 1019

 Score = 95.9 bits (237), Expect = 1e-18
 Identities = 53/153 (34%), Positives = 85/153 (55%)
 Frame = +2

Query: 50  VAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDV 229
           V+ ++    VVV    SL  +  ++       + F+S    G+FG++F D G +F V D 
Sbjct: 114 VSQLSEFQVVVVTDTISLEEKVKLNEYTHSHGIGFISTETRGLFGNVFVDLGEEFTVIDT 173

Query: 230 NGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKV 409
            GE+P++ ++S I      D  V  LD+ RH  E G++V F+EV+G   LNDG   +++V
Sbjct: 174 TGEEPKTGIVSDIE----SDGTVTMLDDNRHGLEDGNYVKFSEVEGLEKLNDGTPYKVEV 229

Query: 410 LGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           LGP+ F +   ++    +G Y +GG  T+VKMP
Sbjct: 230 LGPFAFKIGSVKD----LGTYKKGGLFTEVKMP 258

[181][TOP]
>UniRef100_UPI0001560BD0 PREDICTED: ubiquitin-like modifier activating enzyme 6 n=1
           Tax=Equus caballus RepID=UPI0001560BD0
          Length = 1041

 Score = 94.4 bits (233), Expect = 4e-18
 Identities = 53/148 (35%), Positives = 81/148 (54%), Gaps = 2/148 (1%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREAD--VKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           Y  VVL    L  Q  ++  CR     +KF+S   +G++  +F DFG +F V D  GE+ 
Sbjct: 143 YQCVVLTEIQLPLQKKINDFCRSQHPPIKFISADIHGIWSRLFCDFGDEFEVLDTTGEES 202

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
           + + IS IT    +  +V CL+   H  ETG  +TF E+ G TGLN G +++I V+ P++
Sbjct: 203 KEIFISNIT--QANPGIVTCLENLPHKLETGQFLTFREINGMTGLN-GSTQQITVVSPFS 259

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F++     +   +  Y+ GG A QVK P
Sbjct: 260 FSI----GDTTELEPYLHGGIAVQVKTP 283

[182][TOP]
>UniRef100_B6ACX4 Ubiquitin-activating enzyme E1 n=1 Tax=Cryptosporidium muris RN66
           RepID=B6ACX4_9CRYT
          Length = 1082

 Score = 94.0 bits (232), Expect = 5e-18
 Identities = 56/152 (36%), Positives = 86/152 (56%), Gaps = 2/152 (1%)
 Frame = +2

Query: 59  VAAKYTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVN 232
           +  ++ VVV  +  L  Q + ++ CR     VKF+S  + G+ GSIF DFGP+F V D  
Sbjct: 127 IILEHDVVVCSDIPLRQQLLYNSYCRLRTPSVKFISANSLGLCGSIFVDFGPEFCVFDST 186

Query: 233 GEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVL 412
           GE+P+S +I+ I+ +      V CL E+   F+ GD+VTF E+QG + LN+    +I V 
Sbjct: 187 GEEPKSAIIANIS-KGSSPTTVTCLAEKILPFQDGDYVTFREIQGMSELNESGPYKITVT 245

Query: 413 GPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           G + F +     +   +  Y+R G  TQVK+P
Sbjct: 246 GKHQFTI---DIDTNDLSPYLREGIVTQVKVP 274

[183][TOP]
>UniRef100_Q6BL12 Ubiquitin-activating enzyme E1 n=1 Tax=Debaryomyces hansenii
           RepID=Q6BL12_DEBHA
          Length = 1021

 Score = 94.0 bits (232), Expect = 5e-18
 Identities = 53/157 (33%), Positives = 82/157 (52%)
 Frame = +2

Query: 38  VADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFV 217
           V D   +  A +  +V  + +L  Q  ++      ++ F+S    G+FG +F DFG  F 
Sbjct: 112 VNDLSESTLASFKCIVATDITLEEQVKLNNFTHPKEIGFISADIRGLFGQVFVDFGKNFN 171

Query: 218 VSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSR 397
           V D  GE+  + ++S I      D  V  LD+ RH  + GD V F+E+QG   LNDG   
Sbjct: 172 VIDQTGEEALTGIVSDIE----KDGTVTMLDDNRHGLQDGDFVKFSEIQGMDKLNDGSPH 227

Query: 398 EIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +++VLGPY F +    +   + G Y++GG   QVK+P
Sbjct: 228 KVEVLGPYAFKI----KMSDSYGTYIKGGLYQQVKVP 260

[184][TOP]
>UniRef100_UPI00003BE2C6 hypothetical protein DEHA0F18645g n=1 Tax=Debaryomyces hansenii
           CBS767 RepID=UPI00003BE2C6
          Length = 1021

 Score = 93.2 bits (230), Expect = 9e-18
 Identities = 53/157 (33%), Positives = 82/157 (52%)
 Frame = +2

Query: 38  VADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFV 217
           V D   +  A +  +V  + +L  Q  ++      ++ F+S    G+FG +F DFG  F 
Sbjct: 112 VNDLSESTLALFKCIVATDITLEEQVKLNNFTHPKEIGFISADIRGLFGQVFVDFGKNFN 171

Query: 218 VSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSR 397
           V D  GE+  + ++S I      D  V  LD+ RH  + GD V F+E+QG   LNDG   
Sbjct: 172 VIDQTGEEALTGIVSDIE----KDGTVTMLDDNRHGLQDGDFVKFSEIQGMDKLNDGSPH 227

Query: 398 EIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +++VLGPY F +    +   + G Y++GG   QVK+P
Sbjct: 228 KVEVLGPYAFKI----KMSDSYGTYIKGGLYQQVKVP 260

[185][TOP]
>UniRef100_UPI000069FA77 Ubiquitin-activating enzyme E1-like protein 2 (Monocyte protein 4)
           (MOP-4). n=1 Tax=Xenopus (Silurana) tropicalis
           RepID=UPI000069FA77
          Length = 1014

 Score = 92.4 bits (228), Expect = 2e-17
 Identities = 54/147 (36%), Positives = 79/147 (53%), Gaps = 2/147 (1%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAAC--READVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           Y  V+L    L+ +  +   C  ++  +KF+S  A+G+   +F DFG +F V+D  GE+P
Sbjct: 121 YQCVILTETRLSLRKKICNFCHAQQPPIKFISSEAFGICAYLFCDFGNEFEVTDTTGEEP 180

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
           + + IS IT       VV C + + H  E G  VTF EV G T LN G   +I V+ PY+
Sbjct: 181 KEIFISNIT--QSTPGVVTCFENRPHKLENGQFVTFREVNGMTSLN-GSRHQITVISPYS 237

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKM 505
           F++     + A M  Y  GG A Q+KM
Sbjct: 238 FSI----GDTAHMEPYQHGGIAVQIKM 260

[186][TOP]
>UniRef100_UPI000069FA76 Ubiquitin-activating enzyme E1-like protein 2 (Monocyte protein 4)
           (MOP-4). n=1 Tax=Xenopus (Silurana) tropicalis
           RepID=UPI000069FA76
          Length = 1019

 Score = 92.4 bits (228), Expect = 2e-17
 Identities = 54/147 (36%), Positives = 79/147 (53%), Gaps = 2/147 (1%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAAC--READVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           Y  V+L    L+ +  +   C  ++  +KF+S  A+G+   +F DFG +F V+D  GE+P
Sbjct: 121 YQCVILTETRLSLRKKICNFCHAQQPPIKFISSEAFGICAYLFCDFGNEFEVTDTTGEEP 180

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
           + + IS IT       VV C + + H  E G  VTF EV G T LN G   +I V+ PY+
Sbjct: 181 KEIFISNIT--QSTPGVVTCFENRPHKLENGQFVTFREVNGMTSLN-GSRHQITVISPYS 237

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKM 505
           F++     + A M  Y  GG A Q+KM
Sbjct: 238 FSI----GDTAHMEPYQHGGIAVQIKM 260

[187][TOP]
>UniRef100_UPI000069FA75 Ubiquitin-activating enzyme E1-like protein 2 (Monocyte protein 4)
           (MOP-4). n=1 Tax=Xenopus (Silurana) tropicalis
           RepID=UPI000069FA75
          Length = 357

 Score = 92.4 bits (228), Expect = 2e-17
 Identities = 54/147 (36%), Positives = 79/147 (53%), Gaps = 2/147 (1%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAAC--READVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           Y  V+L    L+ +  +   C  ++  +KF+S  A+G+   +F DFG +F V+D  GE+P
Sbjct: 121 YQCVILTETRLSLRKKICNFCHAQQPPIKFISSEAFGICAYLFCDFGNEFEVTDTTGEEP 180

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
           + + IS IT       VV C + + H  E G  VTF EV G T LN G   +I V+ PY+
Sbjct: 181 KEIFISNIT--QSTPGVVTCFENRPHKLENGQFVTFREVNGMTSLN-GSRHQITVISPYS 237

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKM 505
           F++     + A M  Y  GG A Q+KM
Sbjct: 238 FSI----GDTAHMEPYQHGGIAVQIKM 260

[188][TOP]
>UniRef100_B3RS11 Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens
           RepID=B3RS11_TRIAD
          Length = 966

 Score = 92.0 bits (227), Expect = 2e-17
 Identities = 53/149 (35%), Positives = 80/149 (53%), Gaps = 2/149 (1%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREAD--VKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQ 241
           +Y  VVL    L  Q VVD  CR  D  + F+S   +G+F  +F DFG  F V D +GE+
Sbjct: 121 QYQCVVLTESPLELQVVVDQFCRSQDPPIAFISADVFGLFSFLFCDFGESFQVIDGDGEE 180

Query: 242 PRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPY 421
           P  +++S ++ +  +  VV  +   RH   TGD+V F E++G T LN+ +  +I V+ P 
Sbjct: 181 PEEILLSNVSKD--NPAVVKTIYGVRHGLTTGDYVKFREIKGMTALNN-RIEQITVISPD 237

Query: 422 TFALVGCREEVAAMGAYVRGGYATQVKMP 508
            F +  C       G+Y  GG   +VK+P
Sbjct: 238 EFTI--CDTTSDQFGSYANGGTCVRVKIP 264

[189][TOP]
>UniRef100_A8QE01 Ubiquitin-activating enzyme E1 n=1 Tax=Brugia malayi
           RepID=A8QE01_BRUMA
          Length = 1028

 Score = 92.0 bits (227), Expect = 2e-17
 Identities = 54/147 (36%), Positives = 84/147 (57%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           ++ + VL +  L+ Q +V+   R+ +  F++  A G+FG +F D G +F V+D+NGE+ +
Sbjct: 125 QFDLTVLTDAPLSMQLIVNDWTRKHNRHFIATDARGLFGIVFVDVGAEFKVNDLNGERCK 184

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
            ++I  +  E GD   V  LD   H  E GD+VTF+EV+G T LN  +  +I +  P  F
Sbjct: 185 ELLIEHVDAETGD---VTTLDNVMHGLEDGDYVTFSEVKGMTELNGIEPLKITIKKPNVF 241

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
            +    + VA    YV GG  TQVK+P
Sbjct: 242 NI---GKVVAKFSPYVEGGRFTQVKVP 265

[190][TOP]
>UniRef100_A0E0I6 Ubiquitin-activating enzyme E1 n=1 Tax=Paramecium tetraurelia
           RepID=A0E0I6_PARTE
          Length = 1032

 Score = 91.7 bits (226), Expect = 3e-17
 Identities = 58/154 (37%), Positives = 90/154 (58%), Gaps = 3/154 (1%)
 Frame = +2

Query: 56  AVAAKYTVVVLVN---QSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSD 226
           A  ++++VVVL +   Q   T+  V+ A R+    F+   + G+FGS F DF  KF + D
Sbjct: 113 ASLSEFSVVVLTDVWDQKFITE--VNEAVRQKGHGFILAHSSGLFGSAFVDFSDKFQIFD 170

Query: 227 VNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIK 406
            NGE+PR  +++ IT E   D +V+ ++++RH F+ GD VTF EV G + +N+ K  +IK
Sbjct: 171 PNGEEPRQAIVAGITNE--VDGIVSTIEDKRHGFQDGDSVTFREVVGMSEVNE-KIFKIK 227

Query: 407 VLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           V  PY F++     +      Y+R G A QVK+P
Sbjct: 228 VKSPYMFSI----GDTTKFSQYLREGIAVQVKVP 257

[191][TOP]
>UniRef100_UPI00016E127D UPI00016E127D related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E127D
          Length = 1027

 Score = 91.3 bits (225), Expect = 3e-17
 Identities = 52/149 (34%), Positives = 79/149 (53%), Gaps = 2/149 (1%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAAC--READVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQ 241
           KY  V+L   ++  Q  V+  C  ++  +KF+S  A+GV   +F DFG +FVVSD  GE+
Sbjct: 124 KYQCVILTEATICLQKRVNDFCHSQQPPIKFLSCDAFGVCVRVFCDFGDEFVVSDPTGEE 183

Query: 242 PRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPY 421
           P+ + I  IT    +  VV C+D + H  +TG  V F EV G   LN       +VL P+
Sbjct: 184 PKEIFIQNIT--QSNPGVVTCMDNRPHGLQTGQSVVFREVNGMEELNGTVQHVSEVLSPH 241

Query: 422 TFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +FA+     + + +  Y  GG+   +K P
Sbjct: 242 SFAI----GDTSQLQPYAHGGFVFLMKTP 266

[192][TOP]
>UniRef100_A0DVJ5 Chromosome undetermined scaffold_66, whole genome shotgun sequence
           n=1 Tax=Paramecium tetraurelia RepID=A0DVJ5_PARTE
          Length = 463

 Score = 90.9 bits (224), Expect = 4e-17
 Identities = 57/154 (37%), Positives = 89/154 (57%), Gaps = 3/154 (1%)
 Frame = +2

Query: 56  AVAAKYTVVVLVN---QSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSD 226
           A  ++Y+VVVL +   Q   T+  V+ A R+    F+   + G+FGS F DF  KF + D
Sbjct: 113 ASLSEYSVVVLTDVWDQKFITE--VNEAVRQKGHGFILAHSSGLFGSTFIDFSDKFQIFD 170

Query: 227 VNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIK 406
            NGE+P+  +++ IT E   + +V+ ++E+RH F+ GD +TF EV G   +ND K  +IK
Sbjct: 171 PNGEEPKQAIVAGITNE--VEGIVSTIEEKRHGFQDGDSITFREVVGMAEVND-KIFKIK 227

Query: 407 VLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           V  P+ F++     +      Y+R G A QVK+P
Sbjct: 228 VKSPFMFSI----GDTTGFSQYLREGIALQVKVP 257

[193][TOP]
>UniRef100_Q23QY3 Ubiquitin-activating enzyme E1 n=1 Tax=Tetrahymena thermophila
           SB210 RepID=Q23QY3_TETTH
          Length = 1091

 Score = 90.5 bits (223), Expect = 6e-17
 Identities = 55/149 (36%), Positives = 86/149 (57%), Gaps = 1/149 (0%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTV-VDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQ 241
           A + VVV+ +     + V ++A CR     F+  G  G++G  F DFG    V D NGE+
Sbjct: 174 ADFDVVVITDNYNQDEIVDINAYCRANKKGFIYSGILGLYGLCFVDFGDSHSVFDTNGEE 233

Query: 242 PRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPY 421
           PR+ ++  +T +D + +V    +++RH F++GD+VTF E+QG + LND K  +I+   P+
Sbjct: 234 PRNSIVVGVT-QDAEGLVTV-HEDKRHGFQSGDYVTFREIQGMSELND-KVFKIEEKSPF 290

Query: 422 TFALVGCREEVAAMGAYVRGGYATQVKMP 508
           TF LVG   +      Y+R G   QVK+P
Sbjct: 291 TFTLVGV--DTTKFQPYLREGIVEQVKVP 317

[194][TOP]
>UniRef100_A4S0T8 Ubiquitin-activating enzyme E1 n=1 Tax=Ostreococcus lucimarinus
           CCE9901 RepID=A4S0T8_OSTLU
          Length = 1009

 Score = 90.1 bits (222), Expect = 8e-17
 Identities = 55/149 (36%), Positives = 85/149 (57%)
 Frame = +2

Query: 56  AVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNG 235
           AV A   VV     S A    ++A CR  +V F+     GVFG++F DFG  F V DV+G
Sbjct: 109 AVKAHSVVVCAGETSEAEAVAINAMCRANNVAFIKTDVRGVFGNVFCDFGDAFNVLDVDG 168

Query: 236 EQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLG 415
           E+  S ++++++  +    +V C++++R + + G  VTF+EV+G T LN G S  +K + 
Sbjct: 169 EEALSCIVASVS--NDSPALVTCIEDERVELQDGQRVTFSEVRGMTELN-GLSVVVKNVK 225

Query: 416 PYTFALVGCREEVAAMGAYVRGGYATQVK 502
            ++F L     + +A   YV GG ATQVK
Sbjct: 226 KHSFEL---DLDTSAFSPYVGGGIATQVK 251

[195][TOP]
>UniRef100_A7SBV9 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7SBV9_NEMVE
          Length = 1013

 Score = 90.1 bits (222), Expect = 8e-17
 Identities = 54/150 (36%), Positives = 77/150 (51%), Gaps = 2/150 (1%)
 Frame = +2

Query: 59  VAAKYTVVVLVNQSLATQTVVDAACR--EADVKFMSVGAYGVFGSIFNDFGPKFVVSDVN 232
           V   Y  V+L +  L+ Q  V++ CR  +   +F+S   YG+FG +F DFG +F V D  
Sbjct: 100 VLKNYQCVILTDAPLSVQLKVNSYCRSQKPQKQFISTSLYGIFGCLFCDFGNEFEVLDTT 159

Query: 233 GEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVL 412
           GE+P+   I  IT ++    VV  LD   H  ETGD +T  E+ G   LN+ +    +VL
Sbjct: 160 GEEPKEFFIGKITKDNPG--VVTTLDNTLHGLETGDTITCKEIVGMEKLNNTQCTVSRVL 217

Query: 413 GPYTFALVGCREEVAAMGAYVRGGYATQVK 502
            PY F +     +    G Y  GG A QV+
Sbjct: 218 SPYAFTISDTTGD--EYGPYKHGGIARQVR 245

[196][TOP]
>UniRef100_UPI00017B1EF5 UPI00017B1EF5 related cluster n=1 Tax=Tetraodon nigroviridis
           RepID=UPI00017B1EF5
          Length = 1027

 Score = 89.7 bits (221), Expect = 1e-16
 Identities = 58/168 (34%), Positives = 87/168 (51%), Gaps = 6/168 (3%)
 Frame = +2

Query: 23  DAAASVADAVAAVA--AKYTVVVLVNQSLATQTVVDAAC--READVKFMS--VGAYGVFG 184
           D ++SV D    +    KY  V+L    +  Q  V+A C  ++  ++F+S  V  +G+  
Sbjct: 107 DVSSSVLDNNTDLGFLRKYQCVILTEARICLQKRVNAFCHSQQPPIRFISSAVMHFGICV 166

Query: 185 SIFNDFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQ 364
            +F DFG +FVVSD  GE+P+ + I  IT   G+  VV C+D + H  +TG  V F EV 
Sbjct: 167 RVFCDFGDEFVVSDPTGEEPKELFIQNIT--QGNPGVVTCMDNRPHGLQTGQSVVFREVH 224

Query: 365 GATGLNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           G   LN    R  +VL PY+FA+     + + +  Y  GG+    K P
Sbjct: 225 GMEELNGTVQRVSEVLSPYSFAV----GDTSQLQPYAHGGFVVLSKTP 268

[197][TOP]
>UniRef100_Q550P6 Putative uncharacterized protein n=1 Tax=Dictyostelium discoideum
           RepID=Q550P6_DICDI
          Length = 1160

 Score = 89.0 bits (219), Expect = 2e-16
 Identities = 48/158 (30%), Positives = 84/158 (53%), Gaps = 13/158 (8%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           ++  ++L   +L  Q  ++  CRE D+KF+    YG+ G +FNDFG +F V D NGE+ +
Sbjct: 150 QFKCIILTESNLNDQIKINEFCRENDIKFIVADCYGLGGWVFNDFGDEFKVYDKNGEELK 209

Query: 248 SVMIS--AITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLND-GKSREIKVLGP 418
            V IS  +I+ ++ + +++ C++   H FE  D++ F E+ G   LND  K  +I ++  
Sbjct: 210 EVFISNISISTQNPNQLIINCMENHIHGFEENDYIQFKEIIGMDQLNDQSKKFKINIINS 269

Query: 419 YTFAL----------VGCREEVAAMGAYVRGGYATQVK 502
             F++               ++ ++  Y RGG A Q K
Sbjct: 270 NCFSINLNDNSNNNNSNSNIDIKSLPPYQRGGIAIQTK 307

[198][TOP]
>UniRef100_A2G7V0 ThiF family protein n=1 Tax=Trichomonas vaginalis G3
           RepID=A2G7V0_TRIVA
          Length = 555

 Score = 89.0 bits (219), Expect = 2e-16
 Identities = 56/148 (37%), Positives = 78/148 (52%), Gaps = 1/148 (0%)
 Frame = +2

Query: 68  KYTVVVLVN-QSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           KY  VVL + +SL     + A C    +K + V   GVFG IF DFG  FV +D  GE+P
Sbjct: 114 KYNCVVLTDWRSLEQIKKIAAICHANSIKLIVVDCRGVFGYIFTDFGASFVSNDAIGERP 173

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
              +I+ IT  + ++  V C  ++ H    GDHV F EV+G T +ND K  E+KV+ P  
Sbjct: 174 SRFLINMIT--NAEEGKVTCDADEPHHLSDGDHVRFEEVEGMTEVND-KEFEVKVISPRQ 230

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F  +G   +     +  R GY  QV +P
Sbjct: 231 FT-IGDTTKFGQYTSVHRSGYGNQVIVP 257

[199][TOP]
>UniRef100_UPI0000F1D484 PREDICTED: similar to ubiquitin-like modifier activating enzyme 6
           n=2 Tax=Danio rerio RepID=UPI0000F1D484
          Length = 1060

 Score = 88.6 bits (218), Expect = 2e-16
 Identities = 51/149 (34%), Positives = 76/149 (51%), Gaps = 2/149 (1%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAAC--READVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQ 241
           +Y  VVL    L  Q  ++  C  ++  +KF+    +G+   +F DFG  F VSD  GE+
Sbjct: 154 RYQCVVLTETKLTLQKRINHFCHTQQPPIKFIGCDVFGICSRVFCDFGETFEVSDPTGEE 213

Query: 242 PRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPY 421
            + + I  I+   G   VV C+D + H  +TG  V   E+ G T LN G   +I VL PY
Sbjct: 214 SKEIFIQNIS--QGSPGVVTCMDSRTHGLQTGQSVCLKEINGMTELN-GTMHQITVLSPY 270

Query: 422 TFALVGCREEVAAMGAYVRGGYATQVKMP 508
           TFA+     + ++   Y  GG+   VK+P
Sbjct: 271 TFAI----GDTSSFQPYTHGGFFRLVKIP 295

[200][TOP]
>UniRef100_Q4RK96 Chromosome 18 SCAF15030, whole genome shotgun sequence. (Fragment)
           n=1 Tax=Tetraodon nigroviridis RepID=Q4RK96_TETNG
          Length = 1026

 Score = 87.8 bits (216), Expect = 4e-16
 Identities = 56/165 (33%), Positives = 82/165 (49%), Gaps = 3/165 (1%)
 Frame = +2

Query: 23  DAAASVADAVAAVA--AKYTVVVLVNQSLATQTVVDAACREADVKF-MSVGAYGVFGSIF 193
           D ++SV D    +    KY  V+L    +  Q  V+A C        ++V  +G+   +F
Sbjct: 94  DVSSSVLDNNTDLGFLRKYQCVILTEARICLQKRVNAFCHSQQPPIRVAVMHFGICVRVF 153

Query: 194 NDFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGAT 373
            DFG +FVVSD  GE+P+ + I  IT   G+  VV C+D + H  +TG  V F EV G  
Sbjct: 154 CDFGDEFVVSDPTGEEPKELFIQNIT--QGNPGVVTCMDNRPHGLQTGQSVVFREVHGME 211

Query: 374 GLNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
            LN    R  +VL PY+FA+     + + +  Y  GG+    K P
Sbjct: 212 ELNGTVQRVSEVLSPYSFAV----GDTSQLQPYAHGGFVVLSKTP 252

[201][TOP]
>UniRef100_C3YBQ2 Putative uncharacterized protein (Fragment) n=1 Tax=Branchiostoma
           floridae RepID=C3YBQ2_BRAFL
          Length = 407

 Score = 87.4 bits (215), Expect = 5e-16
 Identities = 50/119 (42%), Positives = 66/119 (55%)
 Frame = +2

Query: 152 FMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFE 331
           F++   YGVF   F DFG +F V D  GE+P+ V ++ +T       VV CL+ + H FE
Sbjct: 10  FVTGDVYGVFCCCFCDFGDEFEVRDATGEEPKEVFVAKVT--KASPGVVTCLENRMHGFE 67

Query: 332 TGDHVTFTEVQGATGLNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           TGD VTF EV G   LN G S +I V+  Y F++    +E      Y  GG A QVK+P
Sbjct: 68  TGDVVTFKEVTGMDALN-GTSHKISVISSYAFSICDTTDE--KYQPYKHGGIARQVKVP 123

[202][TOP]
>UniRef100_B7G3Z1 Ubiquitin-activating enzyme E1 n=1 Tax=Phaeodactylum tricornutum
           CCAP 1055/1 RepID=B7G3Z1_PHATR
          Length = 1050

 Score = 87.0 bits (214), Expect = 6e-16
 Identities = 61/175 (34%), Positives = 82/175 (46%), Gaps = 7/175 (4%)
 Frame = +2

Query: 5   VSLLAADAAASVADAVAAVAAKYTVVVLVNQSLATQTVV--DAACREADVKFMSVGAYGV 178
           VS+  AD      D+V  +       V+V   L    V+  + ACRE  V F+      V
Sbjct: 108 VSVTTADVPDLSVDSVLPLIDGSLTCVVVTVPLPKALVIQLNEACREQKVSFIYSLTMSV 167

Query: 179 FGSIFNDFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTE 358
           FG  F DFG  FVV+D +GE   +  I ++  E+   VV    D  RH  E GD V+F  
Sbjct: 168 FGMAFCDFGDAFVVADKDGEAAATSQIESVVHEN-PAVVKVLEDHGRHGLEDGDKVSFAR 226

Query: 359 VQGATGLNDGKSREIKVLGPYTFA-----LVGCREEVAAMGAYVRGGYATQVKMP 508
           + G  GL +G+   IK  GP+TF      L G  +   A  A  + GY TQ+K P
Sbjct: 227 LHGVPGLEEGREYAIKTTGPFTFELPEVDLSGIADGDGAGHAVNQQGYITQIKQP 281

[203][TOP]
>UniRef100_A9TU56 Ubiquitin-activating enzyme E1 n=1 Tax=Physcomitrella patens subsp.
           patens RepID=A9TU56_PHYPA
          Length = 1030

 Score = 85.9 bits (211), Expect = 1e-15
 Identities = 51/164 (31%), Positives = 81/164 (49%)
 Frame = +2

Query: 17  AADAAASVADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFN 196
           +AD     + AV +    Y  +V  + S      +++ CR   V F++    GVF  +F 
Sbjct: 115 SADIVTLSSVAVESSLGSYGFIVATSGSYPDLIHLNSVCRSLGVPFVAANCRGVFSFVFA 174

Query: 197 DFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATG 376
           DFG  F + D  GE    +++  IT +    V V  ++EQRH  E GD V F+ ++G   
Sbjct: 175 DFGDNFSILDETGEPAGPILLEGITQDFPATVTV--VEEQRHGLENGDKVVFSGIKGMEE 232

Query: 377 LNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           LN      + V G ++F +   +E+  A G Y+ GGY T++K P
Sbjct: 233 LNRDTPYLVTVTGVHSFII---QEDTRAYGRYLSGGYFTKLKTP 273

[204][TOP]
>UniRef100_UPI000012287B Hypothetical protein CBG03440 n=1 Tax=Caenorhabditis briggsae AF16
           RepID=UPI000012287B
          Length = 1111

 Score = 85.1 bits (209), Expect = 2e-15
 Identities = 55/164 (33%), Positives = 77/164 (46%)
 Frame = +2

Query: 17  AADAAASVADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFN 196
           + +   S AD        + +VVL + +   Q  V +  R  + + +   A GVF  IFN
Sbjct: 191 SVNVEVSTADLTEDFVKNFDLVVLTDATRTQQLQVSSWTRSHNRRILIADARGVFSYIFN 250

Query: 197 DFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATG 376
           DFG  F + D  GEQ R   I  I    G+   V  L+   H  E GDHVTF+EV+G  G
Sbjct: 251 DFGDNFRIDDTTGEQVREFFIEHIDRTTGE---VTTLENLFHGLEDGDHVTFSEVKGLDG 307

Query: 377 LNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +N  +  +I V     F +    E  A+   Y+ GG   QVK+P
Sbjct: 308 INGCEPIKITVKNASKFNI---GEFAASFPDYIEGGRCRQVKVP 348

[205][TOP]
>UniRef100_Q014F3 Ubiquitin-activating enzyme E1 n=1 Tax=Ostreococcus tauri
           RepID=Q014F3_OSTTA
          Length = 879

 Score = 85.1 bits (209), Expect = 2e-15
 Identities = 50/146 (34%), Positives = 82/146 (56%)
 Frame = +2

Query: 65  AKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           A Y  VV   Q+  T   ++  CR     F+     GVFGS+F DFG  F V DV+GE+ 
Sbjct: 118 AGYRAVVACEQTEETCKTLNELCRATGAAFIKADVRGVFGSVFCDFGDAFDVVDVDGEEA 177

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
            + ++++++  +    +V C++++R +F+ G  +TF+EV+G T LN G +  +K +  ++
Sbjct: 178 LTSIVASVS--NDFPALVTCIEDERVEFQDGQRITFSEVRGMTELN-GVTCVVKDVKKHS 234

Query: 425 FALVGCREEVAAMGAYVRGGYATQVK 502
           F L     +  +   YV GG ATQVK
Sbjct: 235 FKL---DLDTTSFSQYVGGGIATQVK 257

[206][TOP]
>UniRef100_A8WV26 Ubiquitin-activating enzyme E1 n=1 Tax=Caenorhabditis briggsae
           RepID=A8WV26_CAEBR
          Length = 1114

 Score = 85.1 bits (209), Expect = 2e-15
 Identities = 55/164 (33%), Positives = 77/164 (46%)
 Frame = +2

Query: 17  AADAAASVADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFN 196
           + +   S AD        + +VVL + +   Q  V +  R  + + +   A GVF  IFN
Sbjct: 194 SVNVEVSTADLTEDFVKNFDLVVLTDATRTQQLQVSSWTRSHNRRILIADARGVFSYIFN 253

Query: 197 DFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATG 376
           DFG  F + D  GEQ R   I  I    G+   V  L+   H  E GDHVTF+EV+G  G
Sbjct: 254 DFGDNFRIDDTTGEQVREFFIEHIDRTTGE---VTTLENLFHGLEDGDHVTFSEVKGLDG 310

Query: 377 LNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +N  +  +I V     F +    E  A+   Y+ GG   QVK+P
Sbjct: 311 INGCEPIKITVKNASKFNI---GEFAASFPDYIEGGRCRQVKVP 351

[207][TOP]
>UniRef100_Q5CR33 Ubiquitin-activating enzyme E1 (Fragment) n=1 Tax=Cryptosporidium
           parvum Iowa II RepID=Q5CR33_CRYPV
          Length = 1067

 Score = 84.0 bits (206), Expect = 5e-15
 Identities = 53/157 (33%), Positives = 83/157 (52%), Gaps = 2/157 (1%)
 Frame = +2

Query: 44  DAVAAVAAKYTVVVLVNQSLATQTVVDAACRE--ADVKFMSVGAYGVFGSIFNDFGPKFV 217
           +  + V   + V+V  +  L+ Q   +  CR+   ++ F+S  + G+ GSIF DFG  F 
Sbjct: 116 EITSQVIFNHDVIVCADVPLSLQIKYNELCRDHTPNIGFISANSLGLCGSIFVDFGDSFN 175

Query: 218 VSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSR 397
           V D NGE+P+S +I+ I+    +   + CL E+   F+ GD+V F EVQG T LN     
Sbjct: 176 VFDGNGEEPKSAIIAKIS-RGKETTSITCLAEKLLPFQEGDYVMFREVQGMTELNGTGPH 234

Query: 398 EIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +I   G + F +   + + +    Y R G  TQVK+P
Sbjct: 235 KIISTGKHQFTI---QLDSSMFREYEREGLVTQVKVP 268

[208][TOP]
>UniRef100_B9QE74 Ubiquitin-activating enzyme E1 n=1 Tax=Toxoplasma gondii VEG
           RepID=B9QE74_TOXGO
          Length = 1091

 Score = 83.6 bits (205), Expect = 7e-15
 Identities = 52/157 (33%), Positives = 83/157 (52%), Gaps = 2/157 (1%)
 Frame = +2

Query: 44  DAVAAVAAKYTVVVLVNQSLATQTVVDAACREAD--VKFMSVGAYGVFGSIFNDFGPKFV 217
           + +  V +++ VV++          ++A CR A   V F++   +G+  S+F D G +FV
Sbjct: 116 EKLTQVVSRFDVVIVTEAGNEELKKINAFCRSASKPVGFIAANVFGLAASVFVDLGERFV 175

Query: 218 VSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSR 397
             D +GE+PR V+++ IT E      V    ++   F+ GD V F EVQG   +ND +  
Sbjct: 176 CLDSDGEEPREVIVAGITHERA--ATVHTHTDKLLPFQDGDFVVFREVQGME-INDLQPM 232

Query: 398 EIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +I+V G ++F +     +  A   YV GG A QVKMP
Sbjct: 233 QIRVTGKHSFQI----GDTTAFSPYVSGGIARQVKMP 265

[209][TOP]
>UniRef100_B9PTI7 Ubiquitin-activating enzyme E1 n=1 Tax=Toxoplasma gondii GT1
           RepID=B9PTI7_TOXGO
          Length = 1091

 Score = 83.6 bits (205), Expect = 7e-15
 Identities = 52/157 (33%), Positives = 83/157 (52%), Gaps = 2/157 (1%)
 Frame = +2

Query: 44  DAVAAVAAKYTVVVLVNQSLATQTVVDAACREAD--VKFMSVGAYGVFGSIFNDFGPKFV 217
           + +  V +++ VV++          ++A CR A   V F++   +G+  S+F D G +FV
Sbjct: 116 EKLTQVVSRFDVVIVTEAGNEELKKINAFCRSASKPVGFIAANVFGLAASVFVDLGERFV 175

Query: 218 VSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSR 397
             D +GE+PR V+++ IT E      V    ++   F+ GD V F EVQG   +ND +  
Sbjct: 176 CLDSDGEEPREVIVAGITHERA--ATVHTHTDKLLPFQDGDFVVFREVQGME-INDLQPM 232

Query: 398 EIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +I+V G ++F +     +  A   YV GG A QVKMP
Sbjct: 233 QIRVTGKHSFQI----GDTTAFSPYVSGGIARQVKMP 265

[210][TOP]
>UniRef100_Q22KT5 ThiF family protein n=1 Tax=Tetrahymena thermophila SB210
           RepID=Q22KT5_TETTH
          Length = 1013

 Score = 83.2 bits (204), Expect = 9e-15
 Identities = 47/145 (32%), Positives = 82/145 (56%), Gaps = 2/145 (1%)
 Frame = +2

Query: 80  VVLVNQSLATQTVVDAA--CREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRSV 253
           V+++ Q L  + ++D    CRE ++ F+ VG YG++     DFG  + + D +GE     
Sbjct: 114 VIILTQILNEKQMIDINNYCRENNIGFILVGVYGLYCYSMVDFGNNYKLHDRDGEDTYPF 173

Query: 254 MISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFAL 433
           MIS+I+  +    VV  +++ +H+F+TGD +  TEV G   +N  + R +KV+  Y+F++
Sbjct: 174 MISSISKSNPG--VVNLVNQHKHNFQTGDFIRITEVDGMYQVNGQEPRPVKVIDDYSFSI 231

Query: 434 VGCREEVAAMGAYVRGGYATQVKMP 508
               E+      Y +GG+A  VK+P
Sbjct: 232 ----EDTTYYAQYQKGGFAELVKVP 252

[211][TOP]
>UniRef100_Q5CMZ7 Ubiquitin-activating enzyme E1 n=1 Tax=Cryptosporidium hominis
           RepID=Q5CMZ7_CRYHO
          Length = 1062

 Score = 82.8 bits (203), Expect = 1e-14
 Identities = 51/148 (34%), Positives = 80/148 (54%), Gaps = 2/148 (1%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACRE--ADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           + V+V  +  L+ Q   +  CR+   ++ F+S  + G+ GS+F DFG  F V D NGE+P
Sbjct: 120 HDVIVCADVPLSLQIKYNELCRDHTPNIGFISANSLGLCGSVFVDFGDSFNVFDGNGEEP 179

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
           +S +I+ I+    +   + CL E+   F+ GD+V F EVQG T LN     +I   G + 
Sbjct: 180 KSAIIAKIS-RGKETTSITCLAEKLLPFQEGDYVMFREVQGMTELNGTGPHKIISTGKHQ 238

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F +   + + +    Y R G  TQVK+P
Sbjct: 239 FTI---QLDSSMFREYEREGLVTQVKVP 263

[212][TOP]
>UniRef100_UPI0000F2DE0F PREDICTED: similar to Ubiquitin-activating enzyme E1-like n=1
           Tax=Monodelphis domestica RepID=UPI0000F2DE0F
          Length = 1005

 Score = 82.4 bits (202), Expect = 2e-14
 Identities = 47/146 (32%), Positives = 74/146 (50%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL + +L  Q  V + C +  V F+     G+ G +F DFG +F + + +  +P  
Sbjct: 119 FQVVVLTDSTLEEQLQVGSLCHKLGVHFVVASTRGLVGQLFCDFGKEFTIYEPSEAEPLG 178

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
             I  I+   G   ++  L+E  H F+ GD   F+ ++G T LNDG  R ++VL   T  
Sbjct: 179 NSIGHIS--QGSPGILTVLEENGHCFQDGDRAVFSGIEGMTELNDGDPRPVRVLDKRTLE 236

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     + AA   Y+R G  T+VK P
Sbjct: 237 I----GDTAAFSPYLRSGTITKVKKP 258

[213][TOP]
>UniRef100_B6KKS1 Ubiquitin-activating enzyme E1 n=1 Tax=Toxoplasma gondii ME49
           RepID=B6KKS1_TOXGO
          Length = 1091

 Score = 82.4 bits (202), Expect = 2e-14
 Identities = 52/157 (33%), Positives = 82/157 (52%), Gaps = 2/157 (1%)
 Frame = +2

Query: 44  DAVAAVAAKYTVVVLVNQSLATQTVVDAACREAD--VKFMSVGAYGVFGSIFNDFGPKFV 217
           + +  V +++ VV++           +A CR A   V F++   +G+  S+F D G +FV
Sbjct: 116 EKLTQVVSRFDVVIVTEAGNEELKKTNAFCRSASKPVGFIAANVFGLAASVFVDLGERFV 175

Query: 218 VSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSR 397
             D +GE+PR V+++ IT E      V    ++   F+ GD V F EVQG   +ND +  
Sbjct: 176 CLDSDGEEPREVIVAGITHERA--ATVHTHTDKLLPFQDGDFVVFREVQGME-INDLQPM 232

Query: 398 EIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           +I+V G ++F +     +  A   YV GG A QVKMP
Sbjct: 233 QIRVTGKHSFQI----GDTTAFSPYVSGGIARQVKMP 265

[214][TOP]
>UniRef100_UPI00006CB089 ubiquitin-activating enzyme E1 family protein n=1 Tax=Tetrahymena
           thermophila RepID=UPI00006CB089
          Length = 1073

 Score = 81.6 bits (200), Expect = 3e-14
 Identities = 51/150 (34%), Positives = 80/150 (53%), Gaps = 1/150 (0%)
 Frame = +2

Query: 59  VAAKYTVVVLVNQSLATQTV-VDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNG 235
           V + Y VVV  +     + +  +  CRE  + F+     G++G  F DFG K  V D NG
Sbjct: 131 VLSSYNVVVFTDYFNKEKLIEFNNFCREKGIGFIYTANLGLYGCAFVDFGQKHKVFDNNG 190

Query: 236 EQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLG 415
           E P+  ++ +IT +   + +V   +++RH    GDHVTF EVQG T +ND +  ++ V  
Sbjct: 191 EDPKHSIVVSITQD--KEGLVTTHEDKRHGLVDGDHVTFKEVQGMTEVND-QVYKVTVKS 247

Query: 416 PYTFALVGCREEVAAMGAYVRGGYATQVKM 505
           P+TF +    ++ +   AY R G   QVK+
Sbjct: 248 PFTFTIA---QDTSKFKAYQREGIVQQVKV 274

[215][TOP]
>UniRef100_B7PR84 Ubiquitin-activating enzyme E1, putative (Fragment) n=1 Tax=Ixodes
           scapularis RepID=B7PR84_IXOSC
          Length = 667

 Score = 79.3 bits (194), Expect = 1e-13
 Identities = 41/85 (48%), Positives = 58/85 (68%)
 Frame = +2

Query: 254 MISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFAL 433
           M+++I+ +   + VVACL+E RH FE GD+VTF+EV G + +N     ++KVLGPYTF++
Sbjct: 1   MVASISKDK--EAVVACLEETRHGFEDGDYVTFSEVHGMSEINGCPPMKVKVLGPYTFSV 58

Query: 434 VGCREEVAAMGAYVRGGYATQVKMP 508
                + +    YVRGG ATQVKMP
Sbjct: 59  ----GDTSNFSDYVRGGVATQVKMP 79

[216][TOP]
>UniRef100_UPI00006D0DC5 ubiquitin-activating enzyme E1 family protein n=1 Tax=Tetrahymena
            thermophila RepID=UPI00006D0DC5
          Length = 6304

 Score = 77.8 bits (190), Expect = 4e-13
 Identities = 57/171 (33%), Positives = 78/171 (45%), Gaps = 25/171 (14%)
 Frame = +2

Query: 71   YTVVVLVNQ-SLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
            Y +VVL    S+  Q +++  CR   +KF+S    G +  +FNDFG KF V D NGE P+
Sbjct: 5326 YNIVVLTEVLSMKKQILINEFCRSRGIKFISADVLGPWCRLFNDFGDKFEVIDKNGEDPQ 5385

Query: 248  SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSRE--------- 400
             VMI  IT  + +  VV  L   +H FE G+HV F+EV G   L   K +E         
Sbjct: 5386 EVMIKNIT--NAEKGVVTLLPGVKHPFEDGEHVIFSEVLGME-LQQEKGKEETQTMTMMG 5442

Query: 401  ---------------IKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
                           I+V+   +F +   R        YVR G A  +K P
Sbjct: 5443 GDESSKPSINSTIHKIRVINSNSFEIGDTR----GFTNYVRNGIAKNIKTP 5489

[217][TOP]
>UniRef100_Q27481 Ubiquitin-activating enzyme E1 n=1 Tax=Caenorhabditis elegans
           RepID=Q27481_CAEEL
          Length = 1113

 Score = 77.4 bits (189), Expect = 5e-13
 Identities = 50/146 (34%), Positives = 70/146 (47%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + +VVL + +   Q  + A  R  + + +   A GVF  IFNDFG  F + D  GEQ R 
Sbjct: 212 FDLVVLTDAARTAQRQIAAWTRAHNRRILITDARGVFSYIFNDFGDNFRIDDATGEQVRE 271

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
             I  I    G+   V  L+   H  E GDHVTF+EV+G T +N  +  +I V     F 
Sbjct: 272 FFIEHIDKTTGE---VTTLENLFHGLEDGDHVTFSEVKGLTEINGCEPLKITVKNASKFN 328

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +    +   +   Y  GG   QVK+P
Sbjct: 329 I---GDFAVSFSDYKEGGRCRQVKVP 351

[218][TOP]
>UniRef100_C1P636 Ubiquitin-activating enzyme E1 n=2 Tax=Caenorhabditis elegans
           RepID=C1P636_CAEEL
          Length = 1112

 Score = 77.4 bits (189), Expect = 5e-13
 Identities = 50/146 (34%), Positives = 70/146 (47%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + +VVL + +   Q  + A  R  + + +   A GVF  IFNDFG  F + D  GEQ R 
Sbjct: 211 FDLVVLTDAARTAQRQIAAWTRAHNRRILITDARGVFSYIFNDFGDNFRIDDATGEQVRE 270

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
             I  I    G+   V  L+   H  E GDHVTF+EV+G T +N  +  +I V     F 
Sbjct: 271 FFIEHIDKTTGE---VTTLENLFHGLEDGDHVTFSEVKGLTEINGCEPLKITVKNASKFN 327

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +    +   +   Y  GG   QVK+P
Sbjct: 328 I---GDFAVSFSDYKEGGRCRQVKVP 350

[219][TOP]
>UniRef100_A9T3V0 Ubiquitin-activating enzyme E1 n=1 Tax=Physcomitrella patens subsp.
           patens RepID=A9T3V0_PHYPA
          Length = 1039

 Score = 76.3 bits (186), Expect = 1e-12
 Identities = 46/152 (30%), Positives = 75/152 (49%)
 Frame = +2

Query: 47  AVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSD 226
           +V +    Y  VV  +        +++ CR   V F++    GVF  +F+DFG  F V D
Sbjct: 125 SVESALGSYGCVVATSGFYPDLIRLNSLCRSLGVPFVAASCRGVFTFVFSDFGDNFSVLD 184

Query: 227 VNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIK 406
             GE   +V++  IT +    V V  ++EQRH  E GD V  + ++G   LN      + 
Sbjct: 185 ETGELAGAVLVEGITQDFPATVTV--VEEQRHGLENGDEVVLSGIKGMEELNRDTPYSVT 242

Query: 407 VLGPYTFALVGCREEVAAMGAYVRGGYATQVK 502
           V G ++F +   +E+  +   YV GGY +++K
Sbjct: 243 VTGVHSFTI---QEDTRSYERYVSGGYFSKLK 271

[220][TOP]
>UniRef100_Q7RNE0 Ubiquitin-activating enzyme E1 n=1 Tax=Plasmodium yoelii yoelii
           RepID=Q7RNE0_PLAYO
          Length = 1176

 Score = 75.1 bits (183), Expect = 3e-12
 Identities = 45/120 (37%), Positives = 69/120 (57%)
 Frame = +2

Query: 143 DVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRH 322
           ++ F+S   YG+ G IFNDFG  F+  D +GE  +S  IS I ++D + +V    D+   
Sbjct: 229 NIAFLSCNIYGLCGYIFNDFGNNFICYDKDGENVKSCNISKI-VKDVEGIVSFDFDKSL- 286

Query: 323 DFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVK 502
            F+ GD+V FT V+G   +N GK  +IK L  Y+F +     + +  G Y++GG  TQ+K
Sbjct: 287 PFQNGDYVKFTNVEGMNEIN-GKIYQIKNLKKYSFTI----GDTSKFGDYIKGGECTQIK 341

[221][TOP]
>UniRef100_Q4YRJ8 Ubiquitin-activating enzyme e1, putative (Fragment) n=1
           Tax=Plasmodium berghei RepID=Q4YRJ8_PLABE
          Length = 1031

 Score = 75.1 bits (183), Expect = 3e-12
 Identities = 46/120 (38%), Positives = 68/120 (56%)
 Frame = +2

Query: 143 DVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRH 322
           ++ F+S   YG+ G IFNDFG  F+  D +GE  +S  IS I+ +D + +V    D+   
Sbjct: 91  NIAFLSCNVYGLCGYIFNDFGNNFICYDKDGENIKSCNISKIS-KDVNGIVSFDFDKS-S 148

Query: 323 DFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVK 502
            F+ GD V FT V+G T +N GK  +IK L  YTF +     + +    Y++GG  TQ+K
Sbjct: 149 PFQNGDFVKFTNVEGMTEIN-GKIYQIKNLKKYTFTI----GDTSKFSDYIKGGECTQIK 203

[222][TOP]
>UniRef100_UPI000192392E PREDICTED: similar to Ubiquitin-like modifier-activating enzyme 6
           n=1 Tax=Hydra magnipapillata RepID=UPI000192392E
          Length = 991

 Score = 74.7 bits (182), Expect = 3e-12
 Identities = 49/148 (33%), Positives = 74/148 (50%), Gaps = 2/148 (1%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREAD--VKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           Y  VV+     + Q V++  CRE    + F+S    G+F   F DFG +F V+D++GE+ 
Sbjct: 123 YHCVVITEMPFSDQVVLNNFCREQTPPIYFISGDVRGLFSYAFCDFGNEFEVTDIDGEEY 182

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
           R V I +IT    +  VV  L+ + H  +TGD V    + G   LN  K+  ++ L PYT
Sbjct: 183 REVFIGSIT--KSNPAVVGTLESRLHGLQTGDKVLLKGINGMLQLN-FKTFIVQYLTPYT 239

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F+ + C         Y  GG   ++K P
Sbjct: 240 FS-IDCDTSTDDYQIYEHGGVFCKIKTP 266

[223][TOP]
>UniRef100_B5VLV7 YKL210Wp-like protein (Fragment) n=1 Tax=Saccharomyces cerevisiae
           AWRI1631 RepID=B5VLV7_YEAS6
          Length = 231

 Score = 74.7 bits (182), Expect = 3e-12
 Identities = 42/115 (36%), Positives = 61/115 (53%)
 Frame = +2

Query: 44  DAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVS 223
           D V  ++    VV     SL  +  ++  C  + ++F+S    G+FG+ F D G +F V 
Sbjct: 115 DDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVL 174

Query: 224 DVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDG 388
           D  GE+PR+ M+S I      D  V  LD+ RH  E G+ V F+EV+G   LNDG
Sbjct: 175 DPTGEEPRTGMVSDIE----PDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDG 225

[224][TOP]
>UniRef100_B8C120 Ubiquitin activating enzyme (Fragment) n=1 Tax=Thalassiosira
           pseudonana CCMP1335 RepID=B8C120_THAPS
          Length = 977

 Score = 74.3 bits (181), Expect = 4e-12
 Identities = 41/99 (41%), Positives = 59/99 (59%), Gaps = 7/99 (7%)
 Frame = +2

Query: 77  VVVLVNQSLATQTVVDAACREA--DVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           VVV V++S++ Q  ++ ACR +   V F+SV   GV+  IF DFGP FVV D +GE PRS
Sbjct: 110 VVVCVDRSISAQLEMNDACRNSTSSVPFVSVETAGVYSRIFCDFGPSFVVVDEDGETPRS 169

Query: 251 VMISAITLEDGDD-----VVVACLDEQRHDFETGDHVTF 352
            ++  + +  GDD       V CL+ +RHD   G+ + F
Sbjct: 170 TLMEKVEILAGDDGTEQHFTVHCLEGERHDVSRGNVIEF 208

[225][TOP]
>UniRef100_UPI00017B2344 UPI00017B2344 related cluster n=1 Tax=Tetraodon nigroviridis
           RepID=UPI00017B2344
          Length = 912

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 50/147 (34%), Positives = 75/147 (51%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           ++ VVVL   SL  Q      C    ++F+     G+ G +F DFG +F V D +GE P 
Sbjct: 113 RFQVVVLTRSSLDDQKRFGDFCHAQGIRFVVADTKGLCGQLFCDFGEEFEVLDWDGETPE 172

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           +V++  I+ +D   VV+   D   H F     V+F+EVQG T LN     +IK L   +F
Sbjct: 173 TVIVQNIS-KDNPGVVLCAGD---HRFPDDAVVSFSEVQGMTELNGLGPVKIKNLSDSSF 228

Query: 428 ALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++     + +A   Y  GG AT++K P
Sbjct: 229 SI----GDTSAFSEYKCGGMATEIKQP 251

[226][TOP]
>UniRef100_A4VDU7 Putative uncharacterized protein n=1 Tax=Tetrahymena thermophila
           SB210 RepID=A4VDU7_TETTH
          Length = 1493

 Score = 72.8 bits (177), Expect = 1e-11
 Identities = 40/127 (31%), Positives = 67/127 (52%), Gaps = 1/127 (0%)
 Frame = +2

Query: 131 CREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLD 310
           CR  ++ F+  G  G++G  F DFG    + D NGE+P+  +IS+IT +    V +   +
Sbjct: 159 CRAKNIGFIYAGLLGLYGFCFVDFGEDHKILDPNGEEPKQAIISSITNDKAAVVTLLETN 218

Query: 311 EQR-HDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGY 487
           +++ H FE GD+V F EV+G   +N  +  ++K+L  Y   +   + +      Y   G 
Sbjct: 219 QKKSHGFEDGDYVIFKEVEGMDEMNIQEPTQVKILSKYCLEI---QVDTTEFMPYTGRGL 275

Query: 488 ATQVKMP 508
             QVK+P
Sbjct: 276 IEQVKVP 282

[227][TOP]
>UniRef100_A2E718 Ubiquitin-activating enzyme E1 family protein n=1 Tax=Trichomonas
           vaginalis G3 RepID=A2E718_TRIVA
          Length = 1003

 Score = 72.4 bits (176), Expect = 2e-11
 Identities = 45/126 (35%), Positives = 62/126 (49%)
 Frame = +2

Query: 131 CREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLD 310
           C + ++K +     G+FG +FNDFG KF VS+   E P   +I  IT +   D +V   D
Sbjct: 135 CHQKNIKLIITQVSGLFGYVFNDFGEKFYVSEPKDEIPERFLIENITQD--KDGIVTTSD 192

Query: 311 EQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYA 490
             RH    GD V F EV+G   +ND K   +K + PY F+ +G             GGY 
Sbjct: 193 YTRHGLYEGDTVKFEEVEGMEEVND-KLFTVKPINPYKFS-IGDTSGFHPYKNTGSGGYC 250

Query: 491 TQVKMP 508
            QV +P
Sbjct: 251 CQVNLP 256

[228][TOP]
>UniRef100_C6HMK7 Ubiquitin-activating enzyme E1 n=1 Tax=Ajellomyces capsulatus H143
           RepID=C6HMK7_AJECH
          Length = 1030

 Score = 71.6 bits (174), Expect = 3e-11
 Identities = 39/97 (40%), Positives = 59/97 (60%)
 Frame = +2

Query: 218 VSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSR 397
           + D  GE+P S +++ I  E+G   +V+  DE RH     D+V FTEV+G   LN+ + R
Sbjct: 179 IVDATGEEPTSGIVAGID-EEG---LVSASDEARHGLGEDDYVIFTEVKGMEKLNNSEPR 234

Query: 398 EIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           ++ + GPYTF++     +V+ +G Y  GG  TQVKMP
Sbjct: 235 KVDIKGPYTFSI----GDVSGLGTYESGGIFTQVKMP 267

[229][TOP]
>UniRef100_Q4N4F1 Ubiquitin-activating enzyme E1 n=1 Tax=Theileria parva
           RepID=Q4N4F1_THEPA
          Length = 999

 Score = 70.9 bits (172), Expect = 5e-11
 Identities = 45/148 (30%), Positives = 81/148 (54%), Gaps = 4/148 (2%)
 Frame = +2

Query: 77  VVVLVNQSLATQTVVDAACREAD----VKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           VVV  +Q +     ++  CR       V F++   +G+ GS+F DFG  F+  D  G + 
Sbjct: 118 VVVCCDQKIEVLKSLNRICRANSAGKRVGFIACDTFGMIGSVFVDFGDNFISFDPTGTEL 177

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
           ++ +I +IT  +  + +V  + +   DF+TGD+V F+E++G T LN+ +  +IKV    +
Sbjct: 178 KTGIIESIT--NDKEGLVTLITDGVIDFQTGDYVRFSEIEGMTELNNKEPVQIKVNSKNS 235

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F L+G   +++    +  GG  T+V+ P
Sbjct: 236 F-LIG---DLSHYSPHTSGGLVTEVRYP 259

[230][TOP]
>UniRef100_UPI000155FA54 PREDICTED: ubiquitin-like modifier activating enzyme 7 n=1
           Tax=Equus caballus RepID=UPI000155FA54
          Length = 1011

 Score = 70.5 bits (171), Expect = 6e-11
 Identities = 46/146 (31%), Positives = 66/146 (45%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL    L  Q  V   C +  V F+    +G+ G +F DFG  F V D    +P +
Sbjct: 119 FQVVVLTASKLEEQLKVGTLCHKHGVCFLVADTWGLVGQLFCDFGEDFTVQDPTEAEPLT 178

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
             I  IT +    +V    +    +F +GD VTF+ ++G   LND   R I V    T  
Sbjct: 179 AAIQHIT-QGSPGIVTLKKEADGQNFCSGDLVTFSGIEGMVELNDCAPRPIHVQEDGTLE 237

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     +      Y+RGG  T+VK P
Sbjct: 238 I----GDTTTFSCYLRGGAVTEVKRP 259

[231][TOP]
>UniRef100_UPI00015DED55 RIKEN cDNA D330022A01 gene n=1 Tax=Mus musculus RepID=UPI00015DED55
          Length = 940

 Score = 70.5 bits (171), Expect = 6e-11
 Identities = 43/146 (29%), Positives = 68/146 (46%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL +  L  Q  V   C +  V+F+     G+ G +F DFG  F V D    +P +
Sbjct: 110 FQVVVLTDSKLEDQLKVGPLCHKHGVRFLMAETRGLVGRLFCDFGEDFTVLDPTEVEPMT 169

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
             I  I+ +    +V    D +RH F  GD V F++++G   LN    + ++V    +  
Sbjct: 170 AAIQDIS-QGFPGIVTLRGDTKRHSFHDGDLVIFSDIEGMVELNSCSPQSVRVQKDGSLE 228

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     +      Y+RGG  T+VK P
Sbjct: 229 I----GDTTTFSRYLRGGVVTEVKRP 250

[232][TOP]
>UniRef100_Q9ET03 Ube1l (Fragment) n=1 Tax=Mus musculus RepID=Q9ET03_MOUSE
          Length = 775

 Score = 70.5 bits (171), Expect = 6e-11
 Identities = 43/146 (29%), Positives = 68/146 (46%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL +  L  Q  V   C +  V+F+     G+ G +F DFG  F V D    +P +
Sbjct: 110 FQVVVLTDSKLEDQLKVGPLCHKHGVRFLMAETRGLVGRLFCDFGEDFTVLDPTEVEPMT 169

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
             I  I+ +    +V    D +RH F  GD V F++++G   LN    + ++V    +  
Sbjct: 170 AAIQDIS-QGFPGIVTLRGDTKRHSFHDGDLVIFSDIEGMVELNSCSPQSVRVQKDGSLE 228

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     +      Y+RGG  T+VK P
Sbjct: 229 I----GDTTTFSRYLRGGVVTEVKRP 250

[233][TOP]
>UniRef100_Q9DBK7 Putative uncharacterized protein n=1 Tax=Mus musculus
           RepID=Q9DBK7_MOUSE
          Length = 977

 Score = 70.5 bits (171), Expect = 6e-11
 Identities = 43/146 (29%), Positives = 68/146 (46%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL +  L  Q  V   C +  V+F+     G+ G +F DFG  F V D    +P +
Sbjct: 110 FQVVVLTDSKLEDQLKVGPLCHKHGVRFLMAETRGLVGRLFCDFGEDFTVLDPTEVEPMT 169

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
             I  I+ +    +V    D +RH F  GD V F++++G   LN    + ++V    +  
Sbjct: 170 AAIQDIS-QGFPGIVTLRGDTKRHSFHDGDLVIFSDIEGMVELNSCSPQSVRVQKDGSLE 228

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     +      Y+RGG  T+VK P
Sbjct: 229 I----GDTTTFSRYLRGGVVTEVKRP 250

[234][TOP]
>UniRef100_Q8BTN4 Putative uncharacterized protein n=1 Tax=Mus musculus
           RepID=Q8BTN4_MOUSE
          Length = 905

 Score = 70.5 bits (171), Expect = 6e-11
 Identities = 43/146 (29%), Positives = 68/146 (46%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL +  L  Q  V   C +  V+F+     G+ G +F DFG  F V D    +P +
Sbjct: 110 FQVVVLTDSKLEDQLKVGPLCHKHGVRFLMAETRGLVGRLFCDFGEDFTVLDPTEVEPMT 169

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
             I  I+ +    +V    D +RH F  GD V F++++G   LN    + ++V    +  
Sbjct: 170 AAIQDIS-QGFPGIVTLRGDTKRHSFHDGDLVIFSDIEGMVELNSCSPQSVRVQKDGSLE 228

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +     +      Y+RGG  T+VK P
Sbjct: 229 I----GDTTTFSRYLRGGVVTEVKRP 250

[235][TOP]
>UniRef100_B0XC44 Ubiquitin-activating enzyme E1 n=1 Tax=Culex quinquefasciatus
           RepID=B0XC44_CULQU
          Length = 421

 Score = 70.1 bits (170), Expect = 8e-11
 Identities = 39/111 (35%), Positives = 56/111 (50%)
 Frame = +2

Query: 29  AASVADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGP 208
           +A   D       ++  VVL   + A Q  +       ++  +     G+F  IF DFG 
Sbjct: 313 SAYTGDLTEDFLLRFRCVVLTLTAPAEQHRIAEITHRHNIALIIADTRGLFSQIFCDFGT 372

Query: 209 KFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEV 361
            F V D  G  P S M+++IT +   + +V CLDE RH FE GD+VTFTE+
Sbjct: 373 NFTVYDQTGANPGSAMVASITSDP--ESIVTCLDENRHGFEDGDYVTFTEM 421

[236][TOP]
>UniRef100_UPI00016DA402 ubiquitin-activating enzyme E1 n=1 Tax=Culex quinquefasciatus
           RepID=UPI00016DA402
          Length = 376

 Score = 69.7 bits (169), Expect = 1e-10
 Identities = 39/110 (35%), Positives = 55/110 (50%)
 Frame = +2

Query: 29  AASVADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGP 208
           +A   D       ++  VVL   + A Q  +       ++  +     G+F  IF DFG 
Sbjct: 194 SAYTGDLTEDFLLRFRCVVLTLTAPAEQHRIAEITHRHNIALIIADTRGLFSQIFCDFGT 253

Query: 209 KFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTE 358
            F V D  G  P S M+++IT +   + +V CLDE RH FE GD+VTFTE
Sbjct: 254 NFTVYDQTGANPGSAMVASITSDP--ESIVTCLDENRHGFEDGDYVTFTE 301

[237][TOP]
>UniRef100_UPI00016E6DA5 UPI00016E6DA5 related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E6DA5
          Length = 842

 Score = 69.7 bits (169), Expect = 1e-10
 Identities = 48/142 (33%), Positives = 70/142 (49%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           ++ VVVL + SL  Q      C    ++ +     G+FG +F DFG +F V + + E P 
Sbjct: 109 QFQVVVLTDSSLDDQKGFGDFCHAHGIQLVVADTKGLFGQLFCDFGEEFEVLE-DKETPE 167

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           SV++  I+ E+    VV C  E  H    G  V+F+EVQG T LN      IK L P +F
Sbjct: 168 SVIVQNISKENPG--VVLCAGECPHGLSDGAVVSFSEVQGMTELNSAGPMAIKYLSPCSF 225

Query: 428 ALVGCREEVAAMGAYVRGGYAT 493
           ++     + +    Y  GG AT
Sbjct: 226 SIC----DTSDFSEYKCGGVAT 243

[238][TOP]
>UniRef100_UPI00016E6DA4 UPI00016E6DA4 related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E6DA4
          Length = 1004

 Score = 69.7 bits (169), Expect = 1e-10
 Identities = 48/142 (33%), Positives = 70/142 (49%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           ++ VVVL + SL  Q      C    ++ +     G+FG +F DFG +F V + + E P 
Sbjct: 113 QFQVVVLTDSSLDDQKGFGDFCHAHGIQLVVADTKGLFGQLFCDFGEEFEVLE-DKETPE 171

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           SV++  I+ E+    VV C  E  H    G  V+F+EVQG T LN      IK L P +F
Sbjct: 172 SVIVQNISKENPG--VVLCAGECPHGLSDGAVVSFSEVQGMTELNSAGPMAIKYLSPCSF 229

Query: 428 ALVGCREEVAAMGAYVRGGYAT 493
           ++     + +    Y  GG AT
Sbjct: 230 SIC----DTSDFSEYKCGGVAT 247

[239][TOP]
>UniRef100_UPI00016E6B9D UPI00016E6B9D related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E6B9D
          Length = 918

 Score = 69.7 bits (169), Expect = 1e-10
 Identities = 48/142 (33%), Positives = 70/142 (49%)
 Frame = +2

Query: 68  KYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPR 247
           ++ VVVL + SL  Q      C    ++ +     G+FG +F DFG +F V + + E P 
Sbjct: 147 QFQVVVLTDSSLDDQKGFGDFCHAHGIQLVVADTKGLFGQLFCDFGEEFEVLE-DKETPE 205

Query: 248 SVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTF 427
           SV++  I+ E+    VV C  E  H    G  V+F+EVQG T LN      IK L P +F
Sbjct: 206 SVIVQNISKENPG--VVLCAGECPHGLSDGAVVSFSEVQGMTELNSAGPMAIKYLSPCSF 263

Query: 428 ALVGCREEVAAMGAYVRGGYAT 493
           ++     + +    Y  GG AT
Sbjct: 264 SIC----DTSDFSEYKCGGVAT 281

[240][TOP]
>UniRef100_Q8I5F9 Ubiquitin-activating enzyme E1 n=1 Tax=Plasmodium falciparum 3D7
           RepID=Q8I5F9_PLAF7
          Length = 1140

 Score = 69.7 bits (169), Expect = 1e-10
 Identities = 45/120 (37%), Positives = 68/120 (56%), Gaps = 1/120 (0%)
 Frame = +2

Query: 146 VKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRSVMISAITLE-DGDDVVVACLDEQRH 322
           + F+S   YG+ G IF DF  +F+  D NGEQ +S  +S I+ E +G    V+   ++  
Sbjct: 182 IAFLSCNIYGLCGYIFVDFNKEFICYDSNGEQVKSCNVSKISKELEGK---VSFDFDKTS 238

Query: 323 DFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVK 502
            FE GD+V F+ V+G T +N+ K  +IK L  YTF +     + +    Y++GG  TQVK
Sbjct: 239 PFEEGDYVQFSNVEGMTEINN-KIYKIKNLKKYTFEI----GDTSLYSEYIKGGICTQVK 293

[241][TOP]
>UniRef100_Q5GF34 UBA7 protein n=1 Tax=Bos taurus RepID=Q5GF34_BOVIN
          Length = 998

 Score = 69.3 bits (168), Expect = 1e-10
 Identities = 49/163 (30%), Positives = 69/163 (42%), Gaps = 1/163 (0%)
 Frame = +2

Query: 17  AADAAASVADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFN 196
           A   +    D    +   + VVVL    L  Q  V   C E  V F+     G+ G +F 
Sbjct: 101 AVQVSVYTGDITKDLLLDFQVVVLTASRLEEQLRVGTLCHEHGVCFLVADTRGLVGQLFC 160

Query: 197 DFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQ-RHDFETGDHVTFTEVQGAT 373
           DFG  F V D    +P +  I  I+   G   ++   +E   H F TGD VTF+ ++G  
Sbjct: 161 DFGENFTVQDPTEAEPLTANIQHIS--QGSPGILTLREEAGTHHFHTGDWVTFSGIEGMV 218

Query: 374 GLNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVK 502
            LN    R + V    T  +     +  A   Y+RGG  T+VK
Sbjct: 219 ELNGCDPRPLHVREDGTLEI----GDTTAFSCYLRGGAVTEVK 257

[242][TOP]
>UniRef100_Q4UF46 Ubiquitin-activating enzyme E1 n=1 Tax=Theileria annulata
           RepID=Q4UF46_THEAN
          Length = 1007

 Score = 69.3 bits (168), Expect = 1e-10
 Identities = 44/148 (29%), Positives = 82/148 (55%), Gaps = 4/148 (2%)
 Frame = +2

Query: 77  VVVLVNQSLATQTVVDAACREAD----VKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQP 244
           VVV  +Q++     ++  CR       + F++   +G+ GS+F DFG  F+  D  G + 
Sbjct: 118 VVVCCDQNVEVLKNLNRICRANSLGKRIGFIACDTFGMIGSVFVDFGDNFISFDPTGTEL 177

Query: 245 RSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYT 424
           ++ +I +IT  +  + +V  + +   DF+TGD+V F+E++G T LN+ +  +IKV    +
Sbjct: 178 KTGIIESIT--NDKEGLVTLITDGVIDFQTGDYVRFSEIEGMTELNNKEPVQIKVNSKNS 235

Query: 425 FALVGCREEVAAMGAYVRGGYATQVKMP 508
           F L+G   +++    +  GG  T+V+ P
Sbjct: 236 F-LIG---DLSHYTPHTSGGLVTEVRYP 259

[243][TOP]
>UniRef100_UPI00005A3AEC PREDICTED: similar to ubiquitin-activating enzyme E1-like isoform 1
           n=1 Tax=Canis lupus familiaris RepID=UPI00005A3AEC
          Length = 1008

 Score = 68.2 bits (165), Expect = 3e-10
 Identities = 45/146 (30%), Positives = 64/146 (43%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL    L  Q  V   C E  + F+     G+ G +F DFG  F V D    +P +
Sbjct: 119 FQVVVLTTSKLEEQLKVGTLCHELGICFLVADTRGLVGQLFCDFGEDFTVQDPTEAEPLT 178

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
             I  I+ +    ++    +   H F  GD VTF+ ++G   LN    R I+V    T  
Sbjct: 179 AAIQHIS-QGSPGILTLRKETDDHYFCDGDLVTFSGIEGMVELNGCDPRPIRVQEDGTLE 237

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +       A    Y+RGG  T+VK P
Sbjct: 238 I----GNTATFSRYLRGGAVTEVKRP 259

[244][TOP]
>UniRef100_UPI00005A3AEB PREDICTED: similar to ubiquitin-activating enzyme E1-like isoform 3
           n=1 Tax=Canis lupus familiaris RepID=UPI00005A3AEB
          Length = 1006

 Score = 68.2 bits (165), Expect = 3e-10
 Identities = 45/146 (30%), Positives = 64/146 (43%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL    L  Q  V   C E  + F+     G+ G +F DFG  F V D    +P +
Sbjct: 119 FQVVVLTTSKLEEQLKVGTLCHELGICFLVADTRGLVGQLFCDFGEDFTVQDPTEAEPLT 178

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
             I  I+ +    ++    +   H F  GD VTF+ ++G   LN    R I+V    T  
Sbjct: 179 AAIQHIS-QGSPGILTLRKETDDHYFCDGDLVTFSGIEGMVELNGCDPRPIRVQEDGTLE 237

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +       A    Y+RGG  T+VK P
Sbjct: 238 I----GNTATFSRYLRGGAVTEVKRP 259

[245][TOP]
>UniRef100_UPI00005A3AEA PREDICTED: similar to ubiquitin-activating enzyme E1-like isoform 2
           n=1 Tax=Canis lupus familiaris RepID=UPI00005A3AEA
          Length = 969

 Score = 68.2 bits (165), Expect = 3e-10
 Identities = 45/146 (30%), Positives = 64/146 (43%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL    L  Q  V   C E  + F+     G+ G +F DFG  F V D    +P +
Sbjct: 119 FQVVVLTTSKLEEQLKVGTLCHELGICFLVADTRGLVGQLFCDFGEDFTVQDPTEAEPLT 178

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
             I  I+ +    ++    +   H F  GD VTF+ ++G   LN    R I+V    T  
Sbjct: 179 AAIQHIS-QGSPGILTLRKETDDHYFCDGDLVTFSGIEGMVELNGCDPRPIRVQEDGTLE 237

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +       A    Y+RGG  T+VK P
Sbjct: 238 I----GNTATFSRYLRGGAVTEVKRP 259

[246][TOP]
>UniRef100_UPI0000EB1826 Ubiquitin-activating enzyme E1 homolog (D8). n=1 Tax=Canis lupus
           familiaris RepID=UPI0000EB1826
          Length = 1008

 Score = 68.2 bits (165), Expect = 3e-10
 Identities = 45/146 (30%), Positives = 64/146 (43%)
 Frame = +2

Query: 71  YTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFNDFGPKFVVSDVNGEQPRS 250
           + VVVL    L  Q  V   C E  + F+     G+ G +F DFG  F V D    +P +
Sbjct: 119 FQVVVLTTSKLEEQLKVGTLCHELGICFLVADTRGLVGQLFCDFGEDFTVQDPTEAEPLT 178

Query: 251 VMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATGLNDGKSREIKVLGPYTFA 430
             I  I+ +    ++    +   H F  GD VTF+ ++G   LN    R I+V    T  
Sbjct: 179 AAIQHIS-QGSPGILTLRKETDDHYFCDGDLVTFSGIEGMVELNGCDPRPIRVQEDGTLE 237

Query: 431 LVGCREEVAAMGAYVRGGYATQVKMP 508
           +       A    Y+RGG  T+VK P
Sbjct: 238 I----GNTATFSRYLRGGAVTEVKRP 259

[247][TOP]
>UniRef100_UPI0000E1FCC5 PREDICTED: ubiquitin-activating enzyme E1-like n=1 Tax=Pan
           troglodytes RepID=UPI0000E1FCC5
          Length = 986

 Score = 67.8 bits (164), Expect = 4e-10
 Identities = 46/164 (28%), Positives = 67/164 (40%)
 Frame = +2

Query: 17  AADAAASVADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFN 196
           A        D    +   + VVVL    L  Q  V   C +  V F++    G+ G +F 
Sbjct: 75  AVQVVVHTGDITEDLLLDFQVVVLTAAKLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFC 134

Query: 197 DFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATG 376
           DFG  F V D    +P +  I  I+ +    ++        H F  GD VTF+ ++G   
Sbjct: 135 DFGEDFTVQDPTEAEPLTAAIQHIS-QGSPGILTLRKGANTHYFRDGDLVTFSGIEGMVE 193

Query: 377 LNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           LND   R I V    +  +     +      Y+RGG  T+VK P
Sbjct: 194 LNDCDPRSIHVREDGSLEI----GDTTTFSRYLRGGAITEVKRP 233

[248][TOP]
>UniRef100_UPI0000D9A246 PREDICTED: similar to ubiquitin-activating enzyme E1-like isoform 1
           n=1 Tax=Macaca mulatta RepID=UPI0000D9A246
          Length = 908

 Score = 67.8 bits (164), Expect = 4e-10
 Identities = 46/164 (28%), Positives = 67/164 (40%)
 Frame = +2

Query: 17  AADAAASVADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFN 196
           A        D    +   + VVVL    L  Q  V   C +  V F++    G+ G +F 
Sbjct: 101 AVQVVVHTGDITEDLLLDFQVVVLTAAKLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFC 160

Query: 197 DFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATG 376
           DFG  F V D    +P +  I  I+ +    ++        H F  GD VTF+ ++G   
Sbjct: 161 DFGEDFTVQDPTEAEPLTAAIQHIS-QGSPGILTLRKGANTHYFRDGDLVTFSGIEGMVE 219

Query: 377 LNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           LND   R I V    +  +     +      Y+RGG  T+VK P
Sbjct: 220 LNDCDPRSIHVREDGSLEI----GDTTTFSRYLRGGAITEVKRP 259

[249][TOP]
>UniRef100_UPI0000D9A245 PREDICTED: similar to ubiquitin-activating enzyme E1-like isoform 2
           n=1 Tax=Macaca mulatta RepID=UPI0000D9A245
          Length = 1012

 Score = 67.8 bits (164), Expect = 4e-10
 Identities = 46/164 (28%), Positives = 67/164 (40%)
 Frame = +2

Query: 17  AADAAASVADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFN 196
           A        D    +   + VVVL    L  Q  V   C +  V F++    G+ G +F 
Sbjct: 101 AVQVVVHTGDITEDLLLDFQVVVLTAAKLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFC 160

Query: 197 DFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATG 376
           DFG  F V D    +P +  I  I+ +    ++        H F  GD VTF+ ++G   
Sbjct: 161 DFGEDFTVQDPTEAEPLTAAIQHIS-QGSPGILTLRKGANTHYFRDGDLVTFSGIEGMVE 219

Query: 377 LNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           LND   R I V    +  +     +      Y+RGG  T+VK P
Sbjct: 220 LNDCDPRSIHVREDGSLEI----GDTTTFSRYLRGGAITEVKRP 259

[250][TOP]
>UniRef100_P41226 Ubiquitin-like modifier-activating enzyme 7 n=1 Tax=Homo sapiens
           RepID=UBA7_HUMAN
          Length = 1012

 Score = 67.8 bits (164), Expect = 4e-10
 Identities = 46/164 (28%), Positives = 67/164 (40%)
 Frame = +2

Query: 17  AADAAASVADAVAAVAAKYTVVVLVNQSLATQTVVDAACREADVKFMSVGAYGVFGSIFN 196
           A        D    +   + VVVL    L  Q  V   C +  V F++    G+ G +F 
Sbjct: 101 AVQVVVHTGDITEDLLLDFQVVVLTAAKLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFC 160

Query: 197 DFGPKFVVSDVNGEQPRSVMISAITLEDGDDVVVACLDEQRHDFETGDHVTFTEVQGATG 376
           DFG  F V D    +P +  I  I+ +    ++        H F  GD VTF+ ++G   
Sbjct: 161 DFGEDFTVQDPTEAEPLTAAIQHIS-QGSPGILTLRKGANTHYFRDGDLVTFSGIEGMVE 219

Query: 377 LNDGKSREIKVLGPYTFALVGCREEVAAMGAYVRGGYATQVKMP 508
           LND   R I V    +  +     +      Y+RGG  T+VK P
Sbjct: 220 LNDCDPRSIHVREDGSLEI----GDTTTFSRYLRGGAITEVKRP 259