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[1][TOP]
>UniRef100_C6T731 Methylenetetrahydrofolate reductase n=1 Tax=Glycine max
RepID=C6T731_SOYBN
Length = 344
Score = 181 bits (459), Expect = 2e-44
Identities = 89/109 (81%), Positives = 97/109 (88%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK+IEKIH AA++DPN+ FSFEFFPPKTEDGV NL ERMDRMV H+PSFCDITW AGG+
Sbjct: 1 MKIIEKIH-AASADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVVHNPSFCDITWSAGGT 59
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TAD+TL+IA KMQN V VETMMHLTCTNMPVEKID AL TIKSNGLQNV
Sbjct: 60 TADLTLEIANKMQNIVCVETMMHLTCTNMPVEKIDHALHTIKSNGLQNV 108
[2][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 179 bits (453), Expect = 1e-43
Identities = 92/121 (76%), Positives = 97/121 (80%), Gaps = 12/121 (9%)
Frame = +3
Query: 78 MKVIEKIHEAAA------------SDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSP 221
MKVI+KI EAA S NK FSFEFFPPKTEDGV NL ERMDRMVAH+P
Sbjct: 1 MKVIDKIREAAGGGGDANGNGGDNSSSNKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNP 60
Query: 222 SFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQN 401
SFCDITWGAGGSTAD+TLDIA KMQN + VETMMHLTCTNMPVEKID ALETIKSNG+QN
Sbjct: 61 SFCDITWGAGGSTADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQN 120
Query: 402 V 404
V
Sbjct: 121 V 121
[3][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 178 bits (452), Expect = 1e-43
Identities = 89/118 (75%), Positives = 98/118 (83%), Gaps = 9/118 (7%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGG---------FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFC 230
MKVI+KI AAA+ + GG FSFEFFPPKT+DGV NL ERMDRMV+H+PSFC
Sbjct: 1 MKVIDKIRAAAAAGDSNGGDSSSNNKVVFSFEFFPPKTDDGVDNLFERMDRMVSHNPSFC 60
Query: 231 DITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
DITWGAGGSTAD+TLDIA KMQN + VETMMHLTCTNMPVEKID ALETIKSNG+QNV
Sbjct: 61 DITWGAGGSTADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQNV 118
[4][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 176 bits (446), Expect = 7e-43
Identities = 87/109 (79%), Positives = 95/109 (87%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MKVIEKI EAA + + FSFE+FPPKTE+GV NL ERMDRMVAH PSFCDITWGAGGS
Sbjct: 1 MKVIEKIQEAAGN--GRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGS 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TAD+TL+IA +MQN V VETMMHLTCTNMPVEKID ALETIKSNG+QNV
Sbjct: 59 TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNV 107
[5][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 175 bits (443), Expect = 2e-42
Identities = 86/109 (78%), Positives = 95/109 (87%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MKVIEKI +AA + K FSFEFFPPKTEDGV NL ERMDRMVAH P+FCDITWGAGGS
Sbjct: 1 MKVIEKIRDAATEE-GKVVFSFEFFPPKTEDGVDNLFERMDRMVAHGPAFCDITWGAGGS 59
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TAD+TL+I+ KMQN + VETMMHLTCTNMPVEKID AL+TIKSNG+QNV
Sbjct: 60 TADLTLEISNKMQNMICVETMMHLTCTNMPVEKIDHALDTIKSNGIQNV 108
[6][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 175 bits (443), Expect = 2e-42
Identities = 86/109 (78%), Positives = 95/109 (87%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MKVIEKI +AA + K FSFEFFPPKTEDGV NL ERMDRMVAH P+FCDITWGAGGS
Sbjct: 1 MKVIEKIRDAATEE-GKVVFSFEFFPPKTEDGVDNLFERMDRMVAHGPAFCDITWGAGGS 59
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TAD+TL+I+ KMQN + VETMMHLTCTNMPVEKID AL+TIKSNG+QNV
Sbjct: 60 TADLTLEISNKMQNMICVETMMHLTCTNMPVEKIDHALDTIKSNGIQNV 108
[7][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 175 bits (443), Expect = 2e-42
Identities = 86/109 (78%), Positives = 95/109 (87%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MKVIEKI +AA + K FSFEFFPPKTEDGV NL ERMDRMVAH P+FCDITWGAGGS
Sbjct: 1 MKVIEKIRDAATEE-GKVVFSFEFFPPKTEDGVDNLFERMDRMVAHGPAFCDITWGAGGS 59
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TAD+TL+I+ KMQN + VETMMHLTCTNMPVEKID AL+TIKSNG+QNV
Sbjct: 60 TADLTLEISNKMQNMICVETMMHLTCTNMPVEKIDHALDTIKSNGIQNV 108
[8][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 174 bits (442), Expect = 2e-42
Identities = 87/109 (79%), Positives = 94/109 (86%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MKVIEKI EAA + FSFE+FPPKTE+GV NL ERMDRMVAH PSFCDITWGAGGS
Sbjct: 1 MKVIEKILEAAGD--GRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGS 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TAD+TL+IA +MQN V VETMMHLTCTNMPVEKID ALETIKSNG+QNV
Sbjct: 59 TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNV 107
[9][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 174 bits (440), Expect = 4e-42
Identities = 86/109 (78%), Positives = 95/109 (87%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MKVIEKI EAAA + FSFE+FPPKTE+G+ NL ERMDRMVAH P+FCDITWGAGGS
Sbjct: 1 MKVIEKIQEAAAD--GRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGS 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TAD+TL+IA +MQN V VETMMHLTCTNMPVEKIDDAL TIKSNG+QNV
Sbjct: 59 TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNV 107
[10][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 174 bits (440), Expect = 4e-42
Identities = 86/109 (78%), Positives = 95/109 (87%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MKVIEKI EAAA + FSFE+FPPKTE+G+ NL ERMDRMVAH P+FCDITWGAGGS
Sbjct: 1 MKVIEKIQEAAAD--GRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGS 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TAD+TL+IA +MQN V VETMMHLTCTNMPVEKIDDAL TIKSNG+QNV
Sbjct: 59 TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNV 107
[11][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 172 bits (435), Expect = 1e-41
Identities = 85/109 (77%), Positives = 93/109 (85%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MKVI+KI A D K FSFEFFPPKTEDGV NL ERMDRMVA+ P+FCDITWGAGGS
Sbjct: 1 MKVIDKIQSLA--DEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGS 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TAD+TLDIA +MQN V VE+MMHLTCTNMPVEKID ALETI+SNG+QNV
Sbjct: 59 TADLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNV 107
[12][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 169 bits (429), Expect = 7e-41
Identities = 86/122 (70%), Positives = 98/122 (80%), Gaps = 13/122 (10%)
Frame = +3
Query: 78 MKVIEKIHEA--AASDPNKGG-----------FSFEFFPPKTEDGVVNLLERMDRMVAHS 218
MKVI+KI + A+S P+ G FSFEFFPPKTEDGV NL +RMDRMV+H+
Sbjct: 1 MKVIDKIKASVGASSHPHSNGGAISDSNDKVVFSFEFFPPKTEDGVDNLFDRMDRMVSHN 60
Query: 219 PSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQ 398
P+FCDITWGAGGSTAD+TLDIA KMQN + VETMMHLTCTNMPVEKID AL+TIKSNG+Q
Sbjct: 61 PTFCDITWGAGGSTADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALQTIKSNGIQ 120
Query: 399 NV 404
NV
Sbjct: 121 NV 122
[13][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 165 bits (418), Expect = 1e-39
Identities = 82/109 (75%), Positives = 90/109 (82%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MKVIEKI A K FSFEFFPPKTE+GV NL +RMDRMV H PSFCDITWGAGGS
Sbjct: 1 MKVIEKIQNAEKE--GKVVFSFEFFPPKTEEGVENLFDRMDRMVEHQPSFCDITWGAGGS 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TAD+TLDI+ KMQN + VE+MMHLTCTNMPVEKID AL TIK+NG+QNV
Sbjct: 59 TADLTLDISNKMQNMICVESMMHLTCTNMPVEKIDHALATIKANGIQNV 107
[14][TOP]
>UniRef100_Q3EAG8 Methylenetetrahydrofolate reductase n=1 Tax=Arabidopsis thaliana
RepID=Q3EAG8_ARATH
Length = 407
Score = 165 bits (417), Expect = 2e-39
Identities = 77/109 (70%), Positives = 94/109 (86%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MKV++KI + ++ + FSFEFFPPKTEDGV NL ERMDR+V++ P+FCDITWGAGGS
Sbjct: 1 MKVVDKIK--SVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGS 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TAD+TL+IA +MQN + VETMMHLTCTNMP+EKID ALETI+SNG+QNV
Sbjct: 59 TADLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIRSNGIQNV 107
[15][TOP]
>UniRef100_Q9SE60-2 Isoform 2 of Methylenetetrahydrofolate reductase 1 n=1
Tax=Arabidopsis thaliana RepID=Q9SE60-2
Length = 421
Score = 165 bits (417), Expect = 2e-39
Identities = 77/109 (70%), Positives = 94/109 (86%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MKV++KI + ++ + FSFEFFPPKTEDGV NL ERMDR+V++ P+FCDITWGAGGS
Sbjct: 1 MKVVDKIK--SVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGS 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TAD+TL+IA +MQN + VETMMHLTCTNMP+EKID ALETI+SNG+QNV
Sbjct: 59 TADLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIRSNGIQNV 107
[16][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 165 bits (417), Expect = 2e-39
Identities = 77/109 (70%), Positives = 94/109 (86%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MKV++KI + ++ + FSFEFFPPKTEDGV NL ERMDR+V++ P+FCDITWGAGGS
Sbjct: 1 MKVVDKIK--SVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGS 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TAD+TL+IA +MQN + VETMMHLTCTNMP+EKID ALETI+SNG+QNV
Sbjct: 59 TADLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIRSNGIQNV 107
[17][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 155 bits (391), Expect = 2e-36
Identities = 77/112 (68%), Positives = 90/112 (80%), Gaps = 3/112 (2%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGG---FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGA 248
MKVI+KI+ A GG FSFEFFPPKTE+GV NL +RMDRMV H P+FCDITWGA
Sbjct: 1 MKVIDKINNGLA-----GGNVVFSFEFFPPKTEEGVENLFDRMDRMVMHQPAFCDITWGA 55
Query: 249 GGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
GGST+ VTLDIA KMQN + VETMMHLTCTNM VE +D AL+++KSNG+QN+
Sbjct: 56 GGSTSAVTLDIANKMQNMICVETMMHLTCTNMLVETLDGALDSVKSNGIQNI 107
[18][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 155 bits (391), Expect = 2e-36
Identities = 76/112 (67%), Positives = 90/112 (80%), Gaps = 3/112 (2%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGG---FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGA 248
MKVI+KI+ A GG FSFEFFPPKTE+GV NL +RMDRMV H P+FCDITWGA
Sbjct: 1 MKVIDKINNGLA-----GGNVVFSFEFFPPKTEEGVENLFDRMDRMVRHQPAFCDITWGA 55
Query: 249 GGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
GGST+ +TLDIA KMQN + VETMMHLTCTNM VE +D+AL+ +KSNG+QN+
Sbjct: 56 GGSTSAITLDIANKMQNMICVETMMHLTCTNMLVETLDNALDNVKSNGIQNI 107
[19][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 148 bits (374), Expect = 2e-34
Identities = 71/109 (65%), Positives = 85/109 (77%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK+I K+ E + FSFEFFPP+TE+GV NL ER+DRMVA+ P FCDITWGAGGS
Sbjct: 1 MKLIHKVEEKMKK--GETFFSFEFFPPRTEEGVENLFERLDRMVAYGPVFCDITWGAGGS 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TADVTLDIA +MQN + VETMMHLTCTNMP EK++ AL +K G+QN+
Sbjct: 59 TADVTLDIATRMQNLICVETMMHLTCTNMPEEKLESALHEVKKMGVQNI 107
[20][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 145 bits (365), Expect = 2e-33
Identities = 68/83 (81%), Positives = 75/83 (90%)
Frame = +3
Query: 156 PKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTC 335
P+ +GV NL ERMDRMVAH P+FCDITWGAGGSTADVTLDIA +MQN V VETMMHLTC
Sbjct: 13 PRRREGVENLFERMDRMVAHGPNFCDITWGAGGSTADVTLDIANRMQNMVCVETMMHLTC 72
Query: 336 TNMPVEKIDDALETIKSNGLQNV 404
TNMPVEKID+AL+TIKSNG+QNV
Sbjct: 73 TNMPVEKIDNALDTIKSNGIQNV 95
[21][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 126 bits (317), Expect = 7e-28
Identities = 62/109 (56%), Positives = 81/109 (74%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK+I+KI + S N +SFE+FPPKT +GV NL +R+ RM+ P F DITWGAGGS
Sbjct: 4 MKIIDKIQKKKES--NTPFYSFEYFPPKTMEGVQNLYDRLGRMLLFEPLFIDITWGAGGS 61
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T+ +TL+IA+K QN G+ETMMHLTCTNMPV +I AL+ KS G++N+
Sbjct: 62 TSALTLEIAEKAQNVCGLETMMHLTCTNMPVSEIIYALDKAKSTGIRNI 110
[22][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 119 bits (297), Expect = 1e-25
Identities = 57/109 (52%), Positives = 78/109 (71%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK+ +KI ++A +D K +SFE+FPP+T G+ NLL+R++RM A P F DITW AGG
Sbjct: 1 MKITQKIQQSANND--KIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGR 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T+D+T ++ K Q +G+ET MHLTCTNMP EK+D AL K +G +NV
Sbjct: 59 TSDLTSEMVKTCQGLIGMETCMHLTCTNMPKEKVDIALREAKQHGCRNV 107
[23][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 115 bits (287), Expect = 2e-24
Identities = 56/109 (51%), Positives = 74/109 (67%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M + EK+ + A++ + G SFEFFPPKT GV NL +RMDRM A PSF DITWGAGG
Sbjct: 1 MHIKEKLAQNEAAE--RVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGR 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL+ +G N+
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNI 107
[24][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 114 bits (286), Expect = 3e-24
Identities = 56/109 (51%), Positives = 74/109 (67%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M + EK+ + A+ + G SFEFFPPKT GV NL +RMDRM A PSF DITWGAGG
Sbjct: 1 MHISEKLAQNEAA--GRPGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGR 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+D+T ++ Q+ G+ET MHLTCT+MP+EK+D AL++ G N+
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVDAALQSAYKAGCTNI 107
[25][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 114 bits (286), Expect = 3e-24
Identities = 57/109 (52%), Positives = 71/109 (65%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M + EK+ + A K G SFEFFPPKT GV NL +RMDRM PSF DITWGAGG
Sbjct: 1 MHIREKLAKNEAE--GKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGR 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+D+T ++ Q+ G+ET MHLTCT+MPVEK+D AL+ G N+
Sbjct: 59 LSDLTCEMVSVAQSVYGLETCMHLTCTDMPVEKVDQALQAAYKAGCTNI 107
[26][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 114 bits (285), Expect = 3e-24
Identities = 56/111 (50%), Positives = 75/111 (67%), Gaps = 2/111 (1%)
Frame = +3
Query: 78 MKVIEKIHEA--AASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAG 251
MK+ EK+H+A ++ P FSFEFF PKT GV NL +RMDRM +P F DITW AG
Sbjct: 1 MKISEKLHQAHSGSTRPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAG 60
Query: 252 GSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G ++ +T ++ Q+T+G+ET MHLTCTNM +E ID+AL +G QN+
Sbjct: 61 GRSSSLTNEMVYTAQSTLGLETCMHLTCTNMKIELIDEALSKAYKSGCQNI 111
[27][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 114 bits (284), Expect = 4e-24
Identities = 58/110 (52%), Positives = 75/110 (68%), Gaps = 1/110 (0%)
Frame = +3
Query: 78 MKVIEKIHEA-AASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 254
MK+ EK+ +A S+P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MKISEKLTQAHKGSNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 255 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
++ +T ++ Q+T+G+ET MHLTCTNM VE ID+ALE +G QN+
Sbjct: 61 RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALEKAFKSGCQNI 110
[28][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 114 bits (284), Expect = 4e-24
Identities = 58/110 (52%), Positives = 74/110 (67%), Gaps = 1/110 (0%)
Frame = +3
Query: 78 MKVIEKIHEA-AASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 254
MK+ EK+ +A S P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MKISEKLSQAHRGSKPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 255 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
++ +T ++ Q+T+G+ET MHLTCTNM VE ID+ALE +G QN+
Sbjct: 61 RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALEKAYKSGCQNI 110
[29][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 112 bits (281), Expect = 1e-23
Identities = 56/109 (51%), Positives = 72/109 (66%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M + EK+ + A+ + G SFEFFPPKT GV NL +RMDRM A PSF DITWGAGG
Sbjct: 1 MHIKEKLAQNEAA--GRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGR 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL+ G N+
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYKAGCTNI 107
[30][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 112 bits (281), Expect = 1e-23
Identities = 56/109 (51%), Positives = 72/109 (66%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M V +K+++ A + G SFEFFPPKT GV NL +RMDRM A PSF DITWGAGG
Sbjct: 1 MHVKDKLYQNEAG--GQVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGR 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+D+T ++ Q+ G+ET MHLTCT+MP+EK+D AL G N+
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVDAALSAAYKAGCTNI 107
[31][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 112 bits (280), Expect = 1e-23
Identities = 59/112 (52%), Positives = 76/112 (67%), Gaps = 3/112 (2%)
Frame = +3
Query: 78 MKVIEKI---HEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGA 248
MK+ EK+ H+AA S P FSFEFF PKT GV NL +RMDRM +P F DITW A
Sbjct: 1 MKISEKLDQAHKAAHSPP--ATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNA 58
Query: 249 GGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
GG ++ +T ++ Q+T+G+ET MHLTCTNM VE ID+AL+ +G QN+
Sbjct: 59 GGRSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALDKAYKSGCQNI 110
[32][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 112 bits (280), Expect = 1e-23
Identities = 54/109 (49%), Positives = 72/109 (66%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK+ EK+ A + FSFEFF PKT GV NL +RMDRM SP F DITW AGG
Sbjct: 1 MKITEKLSSAHRREDAPPTFSFEFFTPKTAQGVQNLYDRMDRMYNLSPQFIDITWNAGGR 60
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
++++T ++ Q +G+ET MHLTCTNM +E ID+AL++ +G QN+
Sbjct: 61 SSNLTCEMINTAQTVLGLETCMHLTCTNMTLEVIDEALKSAYDSGCQNI 109
[33][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 112 bits (279), Expect = 2e-23
Identities = 54/109 (49%), Positives = 73/109 (66%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M + +K+ A A+ + G SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAHAEAT--GRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+++T ++ Q+ G+ET MHLTCT+MP EK+D AL++ G N+
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDTALQSAFKAGCTNI 107
[34][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 112 bits (279), Expect = 2e-23
Identities = 54/109 (49%), Positives = 73/109 (66%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M + +K+ A A+ + G SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAHAEAT--GRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+++T ++ Q+ G+ET MHLTCT+MP EK+D AL++ G N+
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDTALQSAFKAGCTNI 107
[35][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 111 bits (278), Expect = 2e-23
Identities = 56/110 (50%), Positives = 75/110 (68%), Gaps = 1/110 (0%)
Frame = +3
Query: 78 MKVIEKIHEAAAS-DPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 254
MK+ +K+ +A +S +P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MKISDKLSQAHSSANPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 255 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
++ +T ++ Q+T+G+ET MHLTCTNM VE ID+AL +G QN+
Sbjct: 61 RSSSLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALHKAFESGCQNI 110
[36][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 111 bits (277), Expect = 3e-23
Identities = 53/100 (53%), Positives = 67/100 (67%)
Frame = +3
Query: 105 AAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIA 284
A A + G SFEFFPPKT GV NL +RMDRM PSF DITWGAGG A++T ++
Sbjct: 8 ALAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLAELTCEMV 67
Query: 285 KKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
Q+ G+ET MHLTCT+MP EK+D+AL++ G N+
Sbjct: 68 HVAQSVYGLETCMHLTCTDMPREKVDEALQSAFKAGCTNI 107
[37][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 111 bits (277), Expect = 3e-23
Identities = 54/109 (49%), Positives = 74/109 (67%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M V +K+ E AA+ + G SFE+FPPKT GV NL +RMDRM P+F D+TWGAGGS
Sbjct: 1 MHVGQKLQEQAAT--GRPGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGS 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+++T ++ + Q G+ET MHLTCT+MP E++D ALE + G N+
Sbjct: 59 RSELTCEMVRIAQTVFGLETCMHLTCTDMPRERVDAALEAAYNAGCTNI 107
[38][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 111 bits (277), Expect = 3e-23
Identities = 55/110 (50%), Positives = 74/110 (67%), Gaps = 1/110 (0%)
Frame = +3
Query: 78 MKVIEKIHEA-AASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 254
M++ EK+ +A + S P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MRISEKLSQAHSTSSPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 255 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
++ +T ++ Q+T+G+ET MHLTCTNM +E ID+AL +G QN+
Sbjct: 61 RSSSLTNEMVYTAQSTLGLETCMHLTCTNMKIELIDEALHKAYVSGCQNI 110
[39][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 110 bits (276), Expect = 4e-23
Identities = 53/109 (48%), Positives = 73/109 (66%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M + +K+ A A+ + G SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAHAEAT--GRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+++T ++ Q+ G+ET MHLTCT+MP EK+D A+++ G N+
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAAIQSAFKAGCTNI 107
[40][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 110 bits (276), Expect = 4e-23
Identities = 53/109 (48%), Positives = 73/109 (66%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M + +K+ A A+ + G SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAHAEAT--GRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+++T ++ Q+ G+ET MHLTCT+MP EK+D A+++ G N+
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAAIQSAFKAGCTNI 107
[41][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 110 bits (275), Expect = 5e-23
Identities = 55/110 (50%), Positives = 74/110 (67%), Gaps = 1/110 (0%)
Frame = +3
Query: 78 MKVIEKIHEA-AASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 254
M++ EK+ +A + S P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MRISEKLLQAHSTSSPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 255 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
++ +T ++ Q+T+G+ET MHLTCTNM +E ID+AL +G QN+
Sbjct: 61 RSSSLTNEMVYTAQSTLGLETCMHLTCTNMKIELIDEALHKAYVSGCQNI 110
[42][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 110 bits (275), Expect = 5e-23
Identities = 55/109 (50%), Positives = 71/109 (65%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M + EK+ + A+ K G SFEFFPPKT GV NL +RMDRM PSF DITWGAGG
Sbjct: 1 MHIKEKLAQNEAA--GKIGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGR 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+D+T ++ Q+ G+ET MHLTCT+MP E++D AL+ G N+
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPQERVDAALQAAYKAGCTNI 107
[43][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 110 bits (275), Expect = 5e-23
Identities = 54/110 (49%), Positives = 72/110 (65%), Gaps = 1/110 (0%)
Frame = +3
Query: 78 MKVIEKIHE-AAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 254
M+V EK+ + A+ +K FSFEFF PKT GV NL +RMDRM P F DITW AGG
Sbjct: 1 MRVSEKLQKNREANGTSKATFSFEFFVPKTSQGVQNLYDRMDRMYQTHPQFIDITWNAGG 60
Query: 255 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ ++ ++ Q+ +G+ET MHLTCTNMP + IDDAL+ +G QN+
Sbjct: 61 RLSQLSTELVSTSQSVLGLETCMHLTCTNMPRQLIDDALQKAYESGCQNI 110
[44][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 110 bits (274), Expect = 6e-23
Identities = 54/109 (49%), Positives = 72/109 (66%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M + +K+ A A+ G SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAYAEAT--GHPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+++T ++ Q+ G+ET MHLTCT+MP EK+D AL++ G N+
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPSEKVDAALQSAFKAGCTNI 107
[45][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 110 bits (274), Expect = 6e-23
Identities = 54/109 (49%), Positives = 72/109 (66%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M + +K+ A A+ G SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAYAEAT--GHPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+++T ++ Q+ G+ET MHLTCT+MP EK+D AL++ G N+
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPSEKVDAALQSAFKAGCTNI 107
[46][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 109 bits (273), Expect = 8e-23
Identities = 53/109 (48%), Positives = 72/109 (66%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK+ EK+ +A + +SFEFFPP+T G+ NL +R++RM P F DITWGAGG
Sbjct: 1 MKITEKLQKAEKE--GRPFWSFEFFPPRTAQGLQNLYDRIERMRDLGPEFIDITWGAGGK 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
AD+T + + Q T+G+ET MHL CT MP EK++ AL KS+G QN+
Sbjct: 59 NADLTNSLVQVCQATIGIETCMHLCCTEMPKEKVEWALREAKSHGCQNI 107
[47][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 109 bits (273), Expect = 8e-23
Identities = 54/109 (49%), Positives = 72/109 (66%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M + +K+ A A+ G SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAYAEAT--GHPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+++T ++ Q+ G+ET MHLTCT+MP EK+D AL++ G N+
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAALQSAFKAGCTNI 107
[48][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 109 bits (272), Expect = 1e-22
Identities = 56/110 (50%), Positives = 72/110 (65%), Gaps = 1/110 (0%)
Frame = +3
Query: 78 MKVIEKI-HEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 254
M + +K+ H AA P+ SFEFFPPKT GV NL +RMDRM PSF DITWGAGG
Sbjct: 1 MHIKDKLAHSEAAGRPS---ISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFVDITWGAGG 57
Query: 255 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL++ G N+
Sbjct: 58 RLSDLTAEMVNVSQSVYGLETCMHLTCTDMPREKVDWALQSAYKAGCTNI 107
[49][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 108 bits (271), Expect = 1e-22
Identities = 53/111 (47%), Positives = 74/111 (66%), Gaps = 2/111 (1%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 254
MK+ +K+ + P+K FSFE+F PKT GV NL +RMDRM S P F DITW AGG
Sbjct: 1 MKITQKLADRHKEKPDKATFSFEYFVPKTTQGVQNLYDRMDRMYEASLPEFIDITWNAGG 60
Query: 255 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ ++ ++ Q+ +G+ET MHLTCTNMP+ +ID+ALE ++G QN+
Sbjct: 61 GRLSQLSTELVATAQSVLGLETCMHLTCTNMPISQIDEALEDAYNSGCQNI 111
[50][TOP]
>UniRef100_C5M548 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M548_CANTT
Length = 633
Score = 108 bits (271), Expect = 1e-22
Identities = 51/95 (53%), Positives = 69/95 (72%)
Frame = +3
Query: 120 PNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQN 299
P++ SFEFFPPKT+ G NLL R++RM A +P F ITWGAGGST++ +LD+A Q
Sbjct: 13 PDERFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFITITWGAGGSTSEKSLDLAATCQK 72
Query: 300 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
VG+ T++HLTCTN E ID+AL K+NG++N+
Sbjct: 73 EVGITTVLHLTCTNTNKEIIDEALARAKANGIRNI 107
[51][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 108 bits (271), Expect = 1e-22
Identities = 52/109 (47%), Positives = 73/109 (66%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M + +K+ E S + G SFE+FPPKT GV NL +RMDRM P+F D+TWGAGGS
Sbjct: 1 MHIGQKLQEQETS--GRPGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGS 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+++T ++ + Q G+ET MHLTCT+MP E++D ALE+ + G N+
Sbjct: 59 RSELTCEMVRIAQTVFGLETCMHLTCTDMPRERVDAALESAYNAGCTNI 107
[52][TOP]
>UniRef100_A3LW82 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LW82_PICST
Length = 635
Score = 108 bits (271), Expect = 1e-22
Identities = 51/99 (51%), Positives = 72/99 (72%)
Frame = +3
Query: 108 AASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAK 287
AA P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 9 AALGPDEKFISFEFFPPKTDSGFRNLLARLNRMSALNPLFITVTWGAGGSTSEKSLDLAA 68
Query: 288 KMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
QN +G+ T++HLTCTN E ID+AL+ K +G++N+
Sbjct: 69 TCQNDLGLTTILHLTCTNTNKEIIDEALKRAKESGIRNI 107
[53][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 108 bits (270), Expect = 2e-22
Identities = 55/109 (50%), Positives = 70/109 (64%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M V EK+ + AS + SFEFFPPKT GV NL +RMDRM P+F DITWGAGG
Sbjct: 1 MHVKEKLAHSEAS--GRPSISFEFFPPKTAQGVQNLYDRMDRMHGLGPAFIDITWGAGGR 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL+ G N+
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDWALQCAHKAGCTNI 107
[54][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 108 bits (270), Expect = 2e-22
Identities = 55/109 (50%), Positives = 70/109 (64%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M V EK+ + AS + SFEFFPPKT GV NL +RMDRM P+F DITWGAGG
Sbjct: 1 MHVKEKLAHSEAS--GRPSISFEFFPPKTAQGVQNLYDRMDRMHGLGPAFIDITWGAGGR 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL+ G N+
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDWALQCAHKAGCTNI 107
[55][TOP]
>UniRef100_A9UZU5 Methylenetetrahydrofolate reductase n=1 Tax=Monosiga brevicollis
RepID=A9UZU5_MONBE
Length = 332
Score = 108 bits (269), Expect = 2e-22
Identities = 51/108 (47%), Positives = 72/108 (66%)
Frame = +3
Query: 81 KVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGST 260
K+ +++ E +A + SFEFFPP+T+DGV +L+ R+ R P F D+TWGAGGST
Sbjct: 5 KISDRLQELSAK--GEKFVSFEFFPPRTDDGVTSLMSRIQRYNDQQPLFMDMTWGAGGST 62
Query: 261 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+D+TLD+ +M G MHLTCTNMP EKID AL+ + G++N+
Sbjct: 63 SDLTLDLCTRMVKECGANANMHLTCTNMPSEKIDIALKGARDAGIRNI 110
[56][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 108 bits (269), Expect = 2e-22
Identities = 53/109 (48%), Positives = 69/109 (63%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M++ +K+ + A + FSFEFF PKT GV NL ERMDRM P F DITW AGG
Sbjct: 1 MRISQKL-QRAHEEREDATFSFEFFVPKTSQGVQNLYERMDRMYQTQPEFIDITWNAGGR 59
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ ++ D+ Q +G+ET MHLTCTNMPV +IDDAL+ G +N+
Sbjct: 60 LSMLSTDLVATSQGVLGLETCMHLTCTNMPVSQIDDALKKAYDAGCENI 108
[57][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 108 bits (269), Expect = 2e-22
Identities = 50/91 (54%), Positives = 63/91 (69%)
Frame = +3
Query: 132 GFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 311
G SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +D+T ++ Q+ G+
Sbjct: 17 GISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLSDLTCEMVNVAQSVYGL 76
Query: 312 ETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
ET MHLTCT+MP+EK++ AL G N+
Sbjct: 77 ETCMHLTCTDMPLEKVNAALSAAYKAGCTNI 107
[58][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 108 bits (269), Expect = 2e-22
Identities = 55/113 (48%), Positives = 77/113 (68%), Gaps = 4/113 (3%)
Frame = +3
Query: 78 MKVIEKI--HEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGA 248
M++ EK+ H + ++ P FSFE+F PKT GV NL +RMDRM + P F D+TW A
Sbjct: 1 MRISEKLQNHRSKSTKPT---FSFEYFVPKTTQGVQNLYDRMDRMYQSTLPQFIDVTWNA 57
Query: 249 GGST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
GG + +T D+ + Q+ +G+ET MHLTCTNMPV +IDDALE+ + +G QN+
Sbjct: 58 GGGVLSQLTTDLVETSQSVLGLETCMHLTCTNMPVSQIDDALESARLSGCQNI 110
[59][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 108 bits (269), Expect = 2e-22
Identities = 54/113 (47%), Positives = 72/113 (63%), Gaps = 4/113 (3%)
Frame = +3
Query: 78 MKVIEKIHEA----AASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWG 245
MK+ +K+ +A FSFEFF PKT G+ NL +RMDRM +P F DITW
Sbjct: 1 MKITDKLQQAHSCKVGGSAPPATFSFEFFVPKTSQGLQNLYDRMDRMYDLNPIFIDITWN 60
Query: 246 AGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
AGG ++ +T ++ Q+T+G+ET MHLTCTNMPV ID+ALE +G QN+
Sbjct: 61 AGGRSSTLTNEMVYTAQSTLGLETCMHLTCTNMPVSLIDEALEKAFKSGCQNI 113
[60][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 108 bits (269), Expect = 2e-22
Identities = 50/91 (54%), Positives = 63/91 (69%)
Frame = +3
Query: 132 GFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 311
G SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +D+T ++ Q+ G+
Sbjct: 17 GISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLSDLTCEMVNVAQSVYGL 76
Query: 312 ETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
ET MHLTCT+MP+EK++ AL G N+
Sbjct: 77 ETCMHLTCTDMPLEKVNAALSAAYKAGCTNI 107
[61][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 108 bits (269), Expect = 2e-22
Identities = 50/91 (54%), Positives = 63/91 (69%)
Frame = +3
Query: 132 GFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 311
G SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +D+T ++ Q+ G+
Sbjct: 17 GISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLSDLTCEMVNVAQSVYGL 76
Query: 312 ETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
ET MHLTCT+MP+EK++ AL G N+
Sbjct: 77 ETCMHLTCTDMPLEKVNAALSAAYKAGCTNI 107
[62][TOP]
>UniRef100_Q5A5S8 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5A5S8_CANAL
Length = 640
Score = 107 bits (268), Expect = 3e-22
Identities = 50/99 (50%), Positives = 70/99 (70%)
Frame = +3
Query: 108 AASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAK 287
A+ P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 9 ASLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFVTVTWGAGGSTSEKSLDLAA 68
Query: 288 KMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
QN +G+ T++HLTCTN E ID AL K+ G++N+
Sbjct: 69 TCQNEIGITTVLHLTCTNTNKEVIDQALSRAKAAGVRNI 107
[63][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 107 bits (268), Expect = 3e-22
Identities = 52/108 (48%), Positives = 70/108 (64%)
Frame = +3
Query: 81 KVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGST 260
K+ KI A A + +SFE+FPP+T G+ NL +R++RM P F DITW AGG T
Sbjct: 18 KITNKI--AKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERMADLGPEFVDITWNAGGRT 75
Query: 261 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+D+T + K + +G+ET MHLTCTNMP EKID AL+ K G +N+
Sbjct: 76 SDLTASLVKTVHTYIGLETCMHLTCTNMPREKIDTALKEAKEFGCRNI 123
[64][TOP]
>UniRef100_C4YKV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=C4YKV3_CANAL
Length = 640
Score = 107 bits (268), Expect = 3e-22
Identities = 50/99 (50%), Positives = 70/99 (70%)
Frame = +3
Query: 108 AASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAK 287
A+ P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 9 ASLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFVTVTWGAGGSTSEKSLDLAA 68
Query: 288 KMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
QN +G+ T++HLTCTN E ID AL K+ G++N+
Sbjct: 69 TCQNEIGITTVLHLTCTNTNKEVIDQALSKAKAAGVRNI 107
[65][TOP]
>UniRef100_B9WCV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WCV3_CANDC
Length = 640
Score = 107 bits (268), Expect = 3e-22
Identities = 50/99 (50%), Positives = 70/99 (70%)
Frame = +3
Query: 108 AASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAK 287
A+ P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 9 ASLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFITVTWGAGGSTSEKSLDLAA 68
Query: 288 KMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
QN +G+ T++HLTCTN E ID AL K+ G++N+
Sbjct: 69 TCQNEIGITTVLHLTCTNTNKEVIDQALSKAKAAGVRNI 107
[66][TOP]
>UniRef100_A5DZ35 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DZ35_LODEL
Length = 622
Score = 107 bits (268), Expect = 3e-22
Identities = 48/95 (50%), Positives = 69/95 (72%)
Frame = +3
Query: 120 PNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQN 299
P++ SFEFF PKT+ G NLL R++R++A +P F +TWGAGGST++ +LD+A QN
Sbjct: 13 PDEKFISFEFFSPKTDSGFRNLLARLNRLLAFNPLFITVTWGAGGSTSEKSLDLAATCQN 72
Query: 300 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+G+ T++HLTCTN E ID AL K+NG++N+
Sbjct: 73 KIGINTVLHLTCTNTDKEIIDSALARAKANGIRNI 107
[67][TOP]
>UniRef100_UPI000151A866 hypothetical protein PGUG_01501 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151A866
Length = 642
Score = 107 bits (266), Expect = 5e-22
Identities = 52/109 (47%), Positives = 74/109 (67%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M V++KI+ P SFEFFPPKT+ G NLL R+ RM+A +P F +TWGAGGS
Sbjct: 1 MSVVQKINSLG---PQDRFISFEFFPPKTDTGFRNLLARLHRMLALNPLFITVTWGAGGS 57
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T++ +LD+A Q +G+ T++HLTCTN + ID+AL+ K NG++N+
Sbjct: 58 TSEKSLDLAITCQKELGLTTVLHLTCTNTNKDIIDNALQRAKENGIRNI 106
[68][TOP]
>UniRef100_UPI00003BE162 hypothetical protein DEHA0F09867g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE162
Length = 642
Score = 107 bits (266), Expect = 5e-22
Identities = 50/98 (51%), Positives = 70/98 (71%)
Frame = +3
Query: 111 ASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 290
A P++ SFEFFPPKT+ G NLL R++RM+A +P F +TWGAGGST++ +LD+A
Sbjct: 10 ALKPHERFVSFEFFPPKTDTGFRNLLARLNRMLALNPLFITVTWGAGGSTSEKSLDLAAT 69
Query: 291 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
Q +G+ T++HLTCTN E ID+ALE K G++N+
Sbjct: 70 CQKEIGLTTVLHLTCTNTNKEIIDNALEKAKEQGIRNI 107
[69][TOP]
>UniRef100_Q6BM19 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=Q6BM19_DEBHA
Length = 642
Score = 105 bits (263), Expect = 1e-21
Identities = 50/98 (51%), Positives = 69/98 (70%)
Frame = +3
Query: 111 ASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 290
A P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 10 ALKPHERFVSFEFFPPKTDTGFRNLLARLNRMSALNPLFITVTWGAGGSTSEKSLDLAAT 69
Query: 291 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
Q +G+ T++HLTCTN E ID+ALE K G++N+
Sbjct: 70 CQKEIGLTTVLHLTCTNTNKEIIDNALEKAKEQGIRNI 107
[70][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 105 bits (263), Expect = 1e-21
Identities = 50/98 (51%), Positives = 62/98 (63%)
Frame = +3
Query: 111 ASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 290
A + K FSFEFFPPKT GV NL +RMDRM P F D+TWGAGG + +T ++ K
Sbjct: 10 AREEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHSKLTCEMVKV 69
Query: 291 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
Q G+ET MHLTCT+M K+DDAL +G N+
Sbjct: 70 AQTVYGLETCMHLTCTDMEKSKLDDALREAYQSGCTNI 107
[71][TOP]
>UniRef100_A5DE00 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DE00_PICGU
Length = 642
Score = 105 bits (263), Expect = 1e-21
Identities = 52/109 (47%), Positives = 73/109 (66%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M V++KI+ P SFEFFPPKT+ G NLL R+ RM A +P F +TWGAGGS
Sbjct: 1 MSVVQKINSLG---PQDRFISFEFFPPKTDTGFRNLLARLHRMSALNPLFITVTWGAGGS 57
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T++ +LD+A Q +G+ T++HLTCTN + ID+AL+ K NG++N+
Sbjct: 58 TSEKSLDLAITCQKELGLTTVLHLTCTNTNKDIIDNALQRAKENGIRNI 106
[72][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 105 bits (262), Expect = 2e-21
Identities = 52/109 (47%), Positives = 68/109 (62%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M + +K+ +A A K FSFEFFPPKT GV NL +RMDRM P F D+TWGAGG
Sbjct: 1 MHISQKLAQAKAE--GKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGR 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ +T ++ K Q G+ET MHLTCT+M K+D+AL +G N+
Sbjct: 59 HSKLTCEMVKVAQTVYGLETCMHLTCTDMEKTKLDEALRDAYQSGCTNI 107
[73][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 105 bits (262), Expect = 2e-21
Identities = 50/100 (50%), Positives = 63/100 (63%)
Frame = +3
Query: 105 AAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIA 284
A K FSFE+FPPKT GV NL +RM+RM P F DITWGAGG A++T ++
Sbjct: 3 AETEKTGKPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIAELTCEMV 62
Query: 285 KKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ Q G+ET MHLTCT+M VEK++DAL G N+
Sbjct: 63 TQAQTYFGLETCMHLTCTDMGVEKVNDALSKAYKAGCTNI 102
[74][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 105 bits (261), Expect = 2e-21
Identities = 51/109 (46%), Positives = 71/109 (65%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK+ K+ +A A+D FSFEFF PKT GV NL +RMDRM P F DITW AGG
Sbjct: 1 MKISHKLEKAHAADSTPT-FSFEFFVPKTSQGVNNLYDRMDRMYQLGPQFIDITWNAGGR 59
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+++T ++ Q+ +G+ET MHLTCT MP + +++AL++ G QN+
Sbjct: 60 LSNLTNEMVATAQSALGLETCMHLTCTGMPKQLVENALQSAFDGGCQNI 108
[75][TOP]
>UniRef100_C9S7I4 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S7I4_9PEZI
Length = 181
Score = 105 bits (261), Expect = 2e-21
Identities = 50/100 (50%), Positives = 65/100 (65%)
Frame = +3
Query: 105 AAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIA 284
A A + FSFE+FPPKT GV NL +RMDRM P F DITWGAGG A++T ++
Sbjct: 8 ADAERDGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIAELTCEMV 67
Query: 285 KKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ Q+ G+ET MHLTCT+M +EK++DAL G N+
Sbjct: 68 TQAQSVYGLETCMHLTCTDMGLEKVNDALRKGYKAGCTNI 107
[76][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 105 bits (261), Expect = 2e-21
Identities = 52/100 (52%), Positives = 62/100 (62%)
Frame = +3
Query: 105 AAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIA 284
A A FSFEFFPPKT GV NL +RMDRM PSF DITWGAGG A +T ++
Sbjct: 8 AEAERSGNPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLAQLTCEMV 67
Query: 285 KKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
Q+ G+ET MHLTCT+M EK+D+AL G N+
Sbjct: 68 GVAQSQYGLETCMHLTCTDMGKEKVDEALRNAYKAGCTNI 107
[77][TOP]
>UniRef100_A6SLU6 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6SLU6_BOTFB
Length = 390
Score = 105 bits (261), Expect = 2e-21
Identities = 54/109 (49%), Positives = 67/109 (61%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M + + + EA S FSFEFFPPKT GV NL +RMDRM PSF DITWGAGG
Sbjct: 1 MHIKDMLSEAERS--GNPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGR 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
A +T ++ Q+ G+ET MHLTCT+M EK+D+AL G N+
Sbjct: 59 LAQLTCEMVGVAQSQYGLETCMHLTCTDMGKEKVDEALRNAYKAGCTNI 107
[78][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 103 bits (258), Expect = 5e-21
Identities = 52/109 (47%), Positives = 70/109 (64%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M + + +++A S + FSFE+FPPKT GV NL +RMDRM P F DITWGAGG
Sbjct: 1 MHIKDMLNDAERS--GQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGR 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
A++T ++ + Q G+ET MHLTCT+M VEK++DAL G N+
Sbjct: 59 IAELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNI 107
[79][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 103 bits (258), Expect = 5e-21
Identities = 53/109 (48%), Positives = 69/109 (63%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M + E + +A S + FSFE+FPPKT GV NL +RMDRM P F DITWGAGG
Sbjct: 1 MHIKEMLTDAERS--GQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGR 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
A++T ++ + Q G+ET MHLTCT+M VEK++DAL G N+
Sbjct: 59 IAELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNI 107
[80][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 103 bits (257), Expect = 6e-21
Identities = 54/111 (48%), Positives = 71/111 (63%), Gaps = 2/111 (1%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 254
MK+ EK+ + + K +SFE+F PKT GV NL +RMDRM S P F DITW AGG
Sbjct: 1 MKITEKLEQHRQTS-GKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGG 59
Query: 255 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ ++ D+ Q+ +G+ET MHLTCTNMP+ IDDALE +G QN+
Sbjct: 60 GRLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNI 110
[81][TOP]
>UniRef100_C5DPF1 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5DPF1_ZYGRC
Length = 650
Score = 103 bits (257), Expect = 6e-21
Identities = 50/89 (56%), Positives = 60/89 (67%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
S EFFPPKTE G NLLERM+RM A P F +TWGAGGSTA+ TL++A Q + +
Sbjct: 16 SLEFFPPKTETGKQNLLERMERMTALGPLFATVTWGAGGSTAEKTLELASLAQKNLNLPI 75
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
MHLTCTNM IDDAL K+ G+ N+
Sbjct: 76 CMHLTCTNMDRNIIDDALTRCKAAGIHNI 104
[82][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 103 bits (257), Expect = 6e-21
Identities = 54/111 (48%), Positives = 71/111 (63%), Gaps = 2/111 (1%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 254
MK+ EK+ + + K +SFE+F PKT GV NL +RMDRM S P F DITW AGG
Sbjct: 1 MKITEKLEQHRQTS-GKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGG 59
Query: 255 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ ++ D+ Q+ +G+ET MHLTCTNMP+ IDDALE +G QN+
Sbjct: 60 GRLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNI 110
[83][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 103 bits (257), Expect = 6e-21
Identities = 54/111 (48%), Positives = 71/111 (63%), Gaps = 2/111 (1%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 254
MK+ EK+ + + K +SFE+F PKT GV NL +RMDRM S P F DITW AGG
Sbjct: 1 MKITEKLEQHRQTS-GKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGG 59
Query: 255 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ ++ D+ Q+ +G+ET MHLTCTNMP+ IDDALE +G QN+
Sbjct: 60 GRLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNI 110
[84][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 102 bits (253), Expect = 2e-20
Identities = 47/90 (52%), Positives = 62/90 (68%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 314
FSFE+FPPKT GV NL +RMDRM P F DITWGAGG A++T ++ + Q +G+E
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIAELTCEMVAQAQAYLGLE 77
Query: 315 TMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T MHLTCT+M EK+++AL+ G N+
Sbjct: 78 TCMHLTCTDMGEEKVNNALQRAYKAGCTNI 107
[85][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 102 bits (253), Expect = 2e-20
Identities = 51/112 (45%), Positives = 67/112 (59%), Gaps = 3/112 (2%)
Frame = +3
Query: 78 MKVIEKIHE---AAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGA 248
M++ +K+ + AA + K FSFEFF PKT GV NL +RMDRM P F DITW A
Sbjct: 1 MRISQKLKQRAGAADEEQPKASFSFEFFVPKTLQGVQNLYDRMDRMYQTQPEFIDITWNA 60
Query: 249 GGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
GG + T ++ Q +G+ET MHLTCTNM +D+ALE G +N+
Sbjct: 61 GGRLSQRTSELVATSQGVLGLETCMHLTCTNMSTALVDEALERAYEAGCENI 112
[86][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 102 bits (253), Expect = 2e-20
Identities = 46/109 (42%), Positives = 73/109 (66%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK+ +KI AA DP++ ++FEFFPP+T+ G NL+ R+ R+ +P +TWGAGGS
Sbjct: 1 MKLSDKI---AAHDPSQPFYTFEFFPPRTDQGFENLVSRISRLATLNPLAISVTWGAGGS 57
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T D +L++A Q ++T++HLTCTNM +D+ L+ ++ G+QN+
Sbjct: 58 TKDRSLELASLTQGDYHLDTLLHLTCTNMEQGLVDEVLKAVRDRGIQNI 106
[87][TOP]
>UniRef100_Q6FNS2 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FNS2_CANGA
Length = 645
Score = 101 bits (251), Expect = 3e-20
Identities = 50/97 (51%), Positives = 65/97 (67%)
Frame = +3
Query: 114 SDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKM 293
SD + S EFFPPKTE G NLLERM+RM A P F +TWGAGGST++ TL++A+
Sbjct: 8 SDRDGPLISLEFFPPKTESGKRNLLERMERMSALDPLFITVTWGAGGSTSEKTLELAQIA 67
Query: 294 QNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
Q + V MHLTCTNM I +AL+ +S G++N+
Sbjct: 68 QRDLNVPICMHLTCTNMDTTLIKEALDACRSYGIKNI 104
[88][TOP]
>UniRef100_C4Y9Q4 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y9Q4_CLAL4
Length = 601
Score = 101 bits (251), Expect = 3e-20
Identities = 51/109 (46%), Positives = 72/109 (66%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M V+E+I A P++ SFEFFPPKT+ G NLL R+ RM +P F +TWGAGGS
Sbjct: 1 MSVVERIQ---ALGPDEKFCSFEFFPPKTDAGFRNLLARLHRMRDLNPLFVSVTWGAGGS 57
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T++ +L++A Q +G+ T++HLTCTN IDDAL K+ G++N+
Sbjct: 58 TSEKSLELAVTCQQLLGISTVLHLTCTNTNKAIIDDALSRAKAAGIRNI 106
[89][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 101 bits (251), Expect = 3e-20
Identities = 47/90 (52%), Positives = 61/90 (67%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 314
FSFE+FPPKT GV NL +RM+RM P F DITWGAGG A++T ++ + Q +G+E
Sbjct: 18 FSFEYFPPKTTQGVQNLYDRMERMNNFGPKFIDITWGAGGRIAELTCEMVVQAQTYLGLE 77
Query: 315 TMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T MHLTCT+M EK++DAL G N+
Sbjct: 78 TCMHLTCTDMGEEKVNDALRKAYKAGCTNI 107
[90][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 100 bits (250), Expect = 4e-20
Identities = 48/100 (48%), Positives = 62/100 (62%)
Frame = +3
Query: 105 AAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIA 284
A A FSFE+FPPKT GV NL +RM+RM P F DITWGAGG A++T ++
Sbjct: 8 AEAERTGNPSFSFEYFPPKTAQGVQNLYDRMERMYNFGPKFVDITWGAGGRIAELTCEMV 67
Query: 285 KKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ Q +G+E MHLTCT+M EK++DAL G N+
Sbjct: 68 VQAQTYLGLEACMHLTCTDMGEEKVNDALRKAYKAGCTNI 107
[91][TOP]
>UniRef100_A7TRT4 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TRT4_VANPO
Length = 645
Score = 99.8 bits (247), Expect = 9e-20
Identities = 48/89 (53%), Positives = 62/89 (69%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
S EFFPPKTE G NLLERM RM A P F +TWGAGG+TA+ TL++A +N++ +
Sbjct: 17 SLEFFPPKTEIGKRNLLERMGRMSAMDPLFVTVTWGAGGTTAEKTLELATLAENSLNLNV 76
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+HLTCTNM ID+ALE K G++N+
Sbjct: 77 CIHLTCTNMSRGIIDEALEACKKIGIRNI 105
[92][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 99.4 bits (246), Expect = 1e-19
Identities = 51/110 (46%), Positives = 73/110 (66%), Gaps = 1/110 (0%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 254
MK+ +K+ D + +S+E+FPPKT GVVNL R++RM P+F D+TWGAGG
Sbjct: 1 MKITDKLQLPEYRD--RVTWSYEYFPPKTSTGVVNLYNRIERMRDWGHPTFVDVTWGAGG 58
Query: 255 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
S++D+T I K Q+ G++T MHLTCTNM ++ID+ALE G +N+
Sbjct: 59 SSSDLTPVIVKVTQSDYGLDTCMHLTCTNMATKQIDEALERAYKVGCRNI 108
[93][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NEV2_COPC7
Length = 617
Score = 99.4 bits (246), Expect = 1e-19
Identities = 48/109 (44%), Positives = 71/109 (65%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK+ +KI E DP+K ++FEFFPP+T+ G NL+ R+ R+ P ITWGAGGS
Sbjct: 1 MKLSQKIAE---HDPSKPFYTFEFFPPRTDQGTENLIARISRLSTLDPLAISITWGAGGS 57
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T + +LD+A Q+ ++T++HLTCTNM IDD L+ +K G++ +
Sbjct: 58 TKERSLDLASITQSQHRLDTILHLTCTNMEQGLIDDVLKDVKDRGIETI 106
[94][TOP]
>UniRef100_A7E9M9 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7E9M9_SCLS1
Length = 663
Score = 99.4 bits (246), Expect = 1e-19
Identities = 54/109 (49%), Positives = 70/109 (64%), Gaps = 1/109 (0%)
Frame = +3
Query: 81 KVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 257
K+ EKI AA P+ FS EFFPPKT G NL R+DRM A P F +TWGAGGS
Sbjct: 3 KITEKI---AALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGS 59
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TA +L++A+ Q +G+ T +HLTCTNM +D ALE K+ G++N+
Sbjct: 60 TATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNI 108
[95][TOP]
>UniRef100_A6RQJ7 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6RQJ7_BOTFB
Length = 663
Score = 99.4 bits (246), Expect = 1e-19
Identities = 54/109 (49%), Positives = 70/109 (64%), Gaps = 1/109 (0%)
Frame = +3
Query: 81 KVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 257
K+ EKI AA P+ FS EFFPPKT G NL R+DRM A P F +TWGAGGS
Sbjct: 3 KITEKI---AALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGS 59
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TA +L++A+ Q +G+ T +HLTCTNM +D ALE K+ G++N+
Sbjct: 60 TATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNI 108
[96][TOP]
>UniRef100_B8NQE8 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus flavus
NRRL3357 RepID=B8NQE8_ASPFN
Length = 738
Score = 99.0 bits (245), Expect = 1e-19
Identities = 59/131 (45%), Positives = 79/131 (60%), Gaps = 2/131 (1%)
Frame = +3
Query: 18 SSTHPYPLSLSLASIKD*NKM-KVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLER 194
SS Y LS + A KM K+ +KI AA P+ FS EFFPPKT+ G NL R
Sbjct: 29 SSLFNYHLSRNFAGTDSGIKMEKITDKI---AALPPDANYFSLEFFPPKTQMGFANLQAR 85
Query: 195 MDRMV-AHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDAL 371
++RM A P F +TWGAGGSTA +L++A+ Q + + T +HLTCTNM +D+AL
Sbjct: 86 LERMAQALRPLFVTVTWGAGGSTAQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDEAL 145
Query: 372 ETIKSNGLQNV 404
E K G++N+
Sbjct: 146 EEAKVLGIRNI 156
[97][TOP]
>UniRef100_C4R2L4 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2L4_PICPG
Length = 596
Score = 98.6 bits (244), Expect = 2e-19
Identities = 49/108 (45%), Positives = 70/108 (64%)
Frame = +3
Query: 81 KVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGST 260
K+I+KI E +SFEFFPPKT++G+ NLL R+ RM +P F +TWGAGG+T
Sbjct: 3 KIIDKIKELKGEP----FYSFEFFPPKTDNGLRNLLARLGRMSMLNPLFVTVTWGAGGTT 58
Query: 261 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ TLD+A Q + + T +HLTCTN + ID+AL+ NG++N+
Sbjct: 59 SSKTLDLAITCQKDLDLTTCIHLTCTNTSKKLIDNALKAAYDNGIKNI 106
[98][TOP]
>UniRef100_B6QFH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QFH8_PENMQ
Length = 710
Score = 98.6 bits (244), Expect = 2e-19
Identities = 53/109 (48%), Positives = 72/109 (66%), Gaps = 1/109 (0%)
Frame = +3
Query: 81 KVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 257
K+ EKI AA P+ FS EFFPPKT+ G VNL R++RM A P F +TWGAGG+
Sbjct: 3 KITEKI---AALPPDSNYFSLEFFPPKTQMGSVNLQARLERMAQALRPLFVTVTWGAGGT 59
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TA +L++A+ Q + + T +HLTCTNM ID+ALE K+ G++N+
Sbjct: 60 TAAKSLELAEICQRQLQLTTCLHLTCTNMTRSLIDEALEQAKALGIRNI 108
[99][TOP]
>UniRef100_Q752W6 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q752W6_ASHGO
Length = 635
Score = 97.8 bits (242), Expect = 3e-19
Identities = 47/97 (48%), Positives = 62/97 (63%)
Frame = +3
Query: 114 SDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKM 293
S+ N+ S EFFPPKT+ G NLL R++RM A P F +TWGAGGSTA+ TL++A
Sbjct: 9 SELNRPSLSLEFFPPKTDSGKSNLLARIERMSAMDPLFITVTWGAGGSTAEKTLELAALA 68
Query: 294 QNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
Q + + MHLTCTNM +D AL K G++N+
Sbjct: 69 QRELNIPVCMHLTCTNMDRTILDKALMRAKEAGIRNI 105
[100][TOP]
>UniRef100_P46151 Methylenetetrahydrofolate reductase 1 n=1 Tax=Saccharomyces
cerevisiae RepID=MTHR1_YEAST
Length = 657
Score = 97.8 bits (242), Expect = 3e-19
Identities = 47/89 (52%), Positives = 59/89 (66%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+ TL +A Q T+ +
Sbjct: 16 SLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAEKTLTLASLAQQTLNIPV 75
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
MHLTCTN IDDAL+ + G++N+
Sbjct: 76 CMHLTCTNTEKAIIDDALDRCYNAGIRNI 104
[101][TOP]
>UniRef100_Q6CEM7 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CEM7_YARLI
Length = 625
Score = 97.4 bits (241), Expect = 4e-19
Identities = 52/109 (47%), Positives = 68/109 (62%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M I K+ A P++ FS EFFPPKT++G+ N R+ RM A P F ITWGAGGS
Sbjct: 1 MSTITKL--IAGLKPDEKFFSLEFFPPKTQNGMANFRARLARMAALKPLFITITWGAGGS 58
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TA +LDIA + Q ++G++ +HLTCTNM ID ALE G+ N+
Sbjct: 59 TAKKSLDIASECQ-SMGLDVCLHLTCTNMDPALIDQALEAASKAGICNI 106
[102][TOP]
>UniRef100_C7GU28 Met12p n=2 Tax=Saccharomyces cerevisiae RepID=C7GU28_YEAS2
Length = 657
Score = 97.4 bits (241), Expect = 4e-19
Identities = 47/89 (52%), Positives = 59/89 (66%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+ TL +A Q T+ +
Sbjct: 16 SLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAEKTLALASLAQQTLNIPV 75
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
MHLTCTN IDDAL+ + G++N+
Sbjct: 76 CMHLTCTNTDKAIIDDALDRCYNAGIRNI 104
[103][TOP]
>UniRef100_B5VTD9 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VTD9_YEAS6
Length = 657
Score = 97.4 bits (241), Expect = 4e-19
Identities = 47/89 (52%), Positives = 59/89 (66%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+ TL +A Q T+ +
Sbjct: 16 SLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAEKTLALASLAQQTLNIPV 75
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
MHLTCTN IDDAL+ + G++N+
Sbjct: 76 CMHLTCTNTDKAIIDDALDRCYNAGIRNI 104
[104][TOP]
>UniRef100_B3LL40 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LL40_YEAS1
Length = 657
Score = 97.4 bits (241), Expect = 4e-19
Identities = 47/89 (52%), Positives = 59/89 (66%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+ TL +A Q T+ +
Sbjct: 16 SLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAEKTLALASLAQQTLNIPV 75
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
MHLTCTN IDDAL+ + G++N+
Sbjct: 76 CMHLTCTNTDKAIIDDALDRCYNAGIRNI 104
[105][TOP]
>UniRef100_A6ZWM3 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae YJM789 RepID=A6ZWM3_YEAS7
Length = 441
Score = 97.4 bits (241), Expect = 4e-19
Identities = 47/89 (52%), Positives = 59/89 (66%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+ TL +A Q T+ +
Sbjct: 16 SLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAEKTLALASLAQQTLNIPV 75
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
MHLTCTN IDDAL+ + G++N+
Sbjct: 76 CMHLTCTNTDKAIIDDALDRCYNAGIRNI 104
[106][TOP]
>UniRef100_C4JM22 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JM22_UNCRE
Length = 709
Score = 97.1 bits (240), Expect = 6e-19
Identities = 52/108 (48%), Positives = 71/108 (65%), Gaps = 2/108 (1%)
Frame = +3
Query: 87 IEKIHEAAASDPNKGGF-SFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 260
+EKI + A+ P F S EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIAALPEDANFFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 261 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
A +L++A+ Q +G+ T +HLTCTNM IDDAL+ K+ G++N+
Sbjct: 61 ASKSLELAEICQRQLGLTTCLHLTCTNMNRALIDDALDEAKALGIRNI 108
[107][TOP]
>UniRef100_B8MDD4 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8MDD4_TALSN
Length = 713
Score = 96.7 bits (239), Expect = 7e-19
Identities = 52/109 (47%), Positives = 70/109 (64%), Gaps = 1/109 (0%)
Frame = +3
Query: 81 KVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 257
K+ EKI AA P FS EFFPPKT+ G VNL R++RM P F +TWGAGG+
Sbjct: 3 KITEKI---AALPPGSNYFSLEFFPPKTQMGSVNLQARLERMAQVLRPLFVTVTWGAGGT 59
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TA +L++A+ Q + + T +HLTCTNM ID+ALE K+ G++N+
Sbjct: 60 TAAKSLELAEICQRQLQLTTCLHLTCTNMTRSLIDEALEQAKALGIKNI 108
[108][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 96.3 bits (238), Expect = 1e-18
Identities = 53/109 (48%), Positives = 71/109 (65%), Gaps = 1/109 (0%)
Frame = +3
Query: 81 KVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 257
K+ +KI AA PN+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPNENYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGS 59
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TA +L++A+ Q + + T +HLTCTNM ID+ALE K G++N+
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNI 108
[109][TOP]
>UniRef100_Q2HBA5 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2HBA5_CHAGB
Length = 643
Score = 96.3 bits (238), Expect = 1e-18
Identities = 52/112 (46%), Positives = 72/112 (64%), Gaps = 2/112 (1%)
Frame = +3
Query: 75 KMKVIEKIHEAAASDP-NKGGFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGA 248
K ++KI + A+ P + FS EFFPPKT G NL R+DRM A P F ++TWGA
Sbjct: 16 KSHAMDKITDKIAALPAGQDYFSLEFFPPKTAMGFSNLRSRLDRMARALRPLFVNVTWGA 75
Query: 249 GGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
GGSTA +L++A+ Q +G+ T +HLTCTNM ID AL+ K+ G++N+
Sbjct: 76 GGSTATKSLELAEICQRELGLTTCLHLTCTNMSRRLIDKALDDAKALGIRNI 127
[110][TOP]
>UniRef100_C8V780 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5AU15] n=2 Tax=Emericella
nidulans RepID=C8V780_EMENI
Length = 684
Score = 96.3 bits (238), Expect = 1e-18
Identities = 52/108 (48%), Positives = 69/108 (63%), Gaps = 2/108 (1%)
Frame = +3
Query: 87 IEKI-HEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 260
+EKI H+ AA P FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKITHKIAALPPGANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST 60
Query: 261 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
A +L++A+ Q + + T +HLTCTNM +D ALE K G++N+
Sbjct: 61 AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNI 108
[111][TOP]
>UniRef100_B2WHR5 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WHR5_PYRTR
Length = 653
Score = 96.3 bits (238), Expect = 1e-18
Identities = 53/108 (49%), Positives = 70/108 (64%), Gaps = 2/108 (1%)
Frame = +3
Query: 87 IEKIHEAAASDPNKGG-FSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 260
+EKI + S P+ FS EFFPPKT G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKITDKINSLPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST 60
Query: 261 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
A +L++A+ Q +G+ T +HLTCTNM + IDDALE K G++N+
Sbjct: 61 ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDDALEQAKVLGIRNI 108
[112][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 96.3 bits (238), Expect = 1e-18
Identities = 53/109 (48%), Positives = 71/109 (65%), Gaps = 1/109 (0%)
Frame = +3
Query: 81 KVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 257
K+ +KI AA PN+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPNENYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGS 59
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TA +L++A+ Q + + T +HLTCTNM ID+ALE K G++N+
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNI 108
[113][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1CZX0_NEOFI
Length = 716
Score = 96.3 bits (238), Expect = 1e-18
Identities = 53/109 (48%), Positives = 71/109 (65%), Gaps = 1/109 (0%)
Frame = +3
Query: 81 KVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 257
K+ +KI AA PN+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 30 KITDKI---AALPPNENYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGS 86
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TA +L++A+ Q + + T +HLTCTNM ID+ALE K G++N+
Sbjct: 87 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNI 135
[114][TOP]
>UniRef100_UPI000023F2EE hypothetical protein FG07127.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023F2EE
Length = 672
Score = 95.9 bits (237), Expect = 1e-18
Identities = 51/108 (47%), Positives = 72/108 (66%), Gaps = 2/108 (1%)
Frame = +3
Query: 87 IEKIHEAAASDPNKGG-FSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 260
++KI + A+ P G FS EFFPPKT G NL +R+ RM A P F ++TWGAGGST
Sbjct: 1 MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST 60
Query: 261 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ +L++A+ Q VG+ T +HLTCTNM + ID+AL K+ G++N+
Sbjct: 61 SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNI 108
[115][TOP]
>UniRef100_Q7S2B6 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S2B6_NEUCR
Length = 681
Score = 95.5 bits (236), Expect = 2e-18
Identities = 50/108 (46%), Positives = 69/108 (63%), Gaps = 2/108 (1%)
Frame = +3
Query: 87 IEKIHE-AAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFCDITWGAGGST 260
+EKI + AA P+ FS EFFPPKT G NL +R++RM P F ++TWGAGGST
Sbjct: 1 MEKITDKVAALPPDSNYFSLEFFPPKTAMGFANLRDRLERMARGLRPLFVNVTWGAGGST 60
Query: 261 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
A +L++A+ Q +G+ T +HLTCTNM +D LE K G++N+
Sbjct: 61 AQKSLELAEICQRELGLTTCLHLTCTNMSRRLLDKTLEDAKVLGIRNI 108
[116][TOP]
>UniRef100_Q2UA39 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus oryzae
RepID=Q2UA39_ASPOR
Length = 690
Score = 95.5 bits (236), Expect = 2e-18
Identities = 51/109 (46%), Positives = 70/109 (64%), Gaps = 1/109 (0%)
Frame = +3
Query: 81 KVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 257
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGS 59
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TA +L++A+ Q + + T +HLTCTNM +D+ALE K G++N+
Sbjct: 60 TAQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNI 108
[117][TOP]
>UniRef100_C9S8T9 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S8T9_9PEZI
Length = 670
Score = 95.5 bits (236), Expect = 2e-18
Identities = 52/109 (47%), Positives = 70/109 (64%), Gaps = 1/109 (0%)
Frame = +3
Query: 81 KVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 257
K+ +KI AA N FS EFFPPKT G NL +R+DRM A P F ++TWGAGGS
Sbjct: 3 KITDKI---AALPANANYFSLEFFPPKTAMGFSNLRDRLDRMERALRPLFVNVTWGAGGS 59
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TA +L++A+ Q +G+ T +HLTCTNM +D AL+ K G++N+
Sbjct: 60 TAFKSLELAEICQRELGLTTCLHLTCTNMSRRLVDKALDDAKVLGIRNI 108
[118][TOP]
>UniRef100_C7YTQ6 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YTQ6_NECH7
Length = 674
Score = 94.7 bits (234), Expect = 3e-18
Identities = 50/108 (46%), Positives = 72/108 (66%), Gaps = 2/108 (1%)
Frame = +3
Query: 87 IEKIHEAAASDPNKGG-FSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 260
+++I + A+ P G FS EFFPPKT G NL +R+ RM A P F ++TWGAGGST
Sbjct: 1 MDRITDRIAALPADGSYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST 60
Query: 261 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ +L++A+ Q +G+ T +HLTCTNM + ID ALE K+ G++N+
Sbjct: 61 SQKSLELAELCQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNI 108
[119][TOP]
>UniRef100_A2QUJ5 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QUJ5_ASPNC
Length = 699
Score = 94.4 bits (233), Expect = 4e-18
Identities = 51/109 (46%), Positives = 70/109 (64%), Gaps = 1/109 (0%)
Frame = +3
Query: 81 KVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 257
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGS 59
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TA +L++A+ Q + + T +HLTCTNM +D+ALE K G++N+
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNI 108
[120][TOP]
>UniRef100_C5GI01 Methylenetetrahydrofolate reductase n=2 Tax=Ajellomyces
dermatitidis RepID=C5GI01_AJEDR
Length = 713
Score = 94.0 bits (232), Expect = 5e-18
Identities = 51/108 (47%), Positives = 70/108 (64%), Gaps = 2/108 (1%)
Frame = +3
Query: 87 IEKIHEAAASDP-NKGGFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 260
+EKI + A+ P N FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIAALPRNANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 261 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
A +L++A+ Q +G+ T +HLTCTNM +D AL K+ G++N+
Sbjct: 61 AAKSLELAEICQRQLGLTTCLHLTCTNMNRSLVDHALSEAKALGIRNI 108
[121][TOP]
>UniRef100_B6HK87 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6HK87_PENCW
Length = 691
Score = 94.0 bits (232), Expect = 5e-18
Identities = 51/109 (46%), Positives = 70/109 (64%), Gaps = 1/109 (0%)
Frame = +3
Query: 81 KVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 257
K+ EKI AA P+ FS EFFPPKT G NL R++RM A P F +TWGAGGS
Sbjct: 4 KITEKI---AALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS 60
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TA +L++A+ Q + + T++HLTCTNM + +D AL+ K G++N+
Sbjct: 61 TAARSLELAEVCQRQLQLTTVLHLTCTNMSRKLVDMALDEAKVLGIRNI 109
[122][TOP]
>UniRef100_A1C4Z1 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C4Z1_ASPCL
Length = 690
Score = 94.0 bits (232), Expect = 5e-18
Identities = 52/109 (47%), Positives = 70/109 (64%), Gaps = 1/109 (0%)
Frame = +3
Query: 81 KVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 257
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPDANYFSLEFFPPKTKMGFANLQARLERMEQALRPLFVTVTWGAGGS 59
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TA +L++A+ Q + + T +HLTCTNM ID+ALE K G++N+
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNI 108
[123][TOP]
>UniRef100_Q0CE17 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CE17_ASPTN
Length = 696
Score = 93.6 bits (231), Expect = 6e-18
Identities = 51/109 (46%), Positives = 69/109 (63%), Gaps = 1/109 (0%)
Frame = +3
Query: 81 KVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 257
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPDSNYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGS 59
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TA +L++A+ Q + + T +HLTCTNM +D ALE K G++N+
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRGLVDKALEEAKVLGIRNI 108
[124][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 93.6 bits (231), Expect = 6e-18
Identities = 45/91 (49%), Positives = 59/91 (64%), Gaps = 1/91 (1%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGGSTADVTLDIAKKMQNTVGV 311
+S+EFFPPKT GV NL R+DRM P F D+TWGAGG+++++T I +Q V
Sbjct: 18 YSYEFFPPKTSTGVQNLYNRIDRMKTWGRPMFVDVTWGAGGTSSELTPGIVNVIQTDFEV 77
Query: 312 ETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+T MHLTCTNM E ID AL+ G +N+
Sbjct: 78 DTCMHLTCTNMSTEMIDAALKRAHETGCRNI 108
[125][TOP]
>UniRef100_Q1DT03 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DT03_COCIM
Length = 711
Score = 93.2 bits (230), Expect = 8e-18
Identities = 50/108 (46%), Positives = 69/108 (63%), Gaps = 2/108 (1%)
Frame = +3
Query: 87 IEKIHEAAASDPNKGG-FSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 260
+EKI A+ P FS EFFPPKT+ G NL R++RM A P F +TWGAGG+T
Sbjct: 1 MEKISNKIAALPEDANYFSLEFFPPKTQMGSANLQARLERMSQALRPLFVTVTWGAGGTT 60
Query: 261 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
A +L++A+ Q +G+ T +HLTCTNM ID AL+ K+ G++N+
Sbjct: 61 ATKSLELAEICQRQLGLTTCLHLTCTNMNRTLIDSALDEAKALGIRNI 108
[126][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 93.2 bits (230), Expect = 8e-18
Identities = 53/109 (48%), Positives = 72/109 (66%), Gaps = 1/109 (0%)
Frame = +3
Query: 81 KVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 257
K+ +KI EA D + FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KISDKI-EALPKDAHY--FSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGS 59
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TA +L++A+ Q +G+ T +HLTCTNM ID+ALE K+ G++N+
Sbjct: 60 TAARSLELAEICQRQLGLTTCLHLTCTNMNRTLIDEALEETKALGIRNI 108
[127][TOP]
>UniRef100_B2B6X0 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B6X0_PODAN
Length = 691
Score = 93.2 bits (230), Expect = 8e-18
Identities = 50/112 (44%), Positives = 72/112 (64%), Gaps = 2/112 (1%)
Frame = +3
Query: 75 KMKVIEKIHEAAASDPNKGGF-SFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGA 248
K ++KI + A+ P + + S EFFPPKT G NL +R+DRM A P F ++TWGA
Sbjct: 16 KNHAMDKITDKIAALPAETNYCSLEFFPPKTAMGFSNLRDRLDRMARALRPLFVNVTWGA 75
Query: 249 GGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
GGSTA +L++A+ Q + + T +HLTCTNM + ID LE K+ G++N+
Sbjct: 76 GGSTATKSLELAEICQRELSLTTCLHLTCTNMSRKLIDKTLEDAKALGIRNI 127
[128][TOP]
>UniRef100_Q6CR34 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CR34_KLULA
Length = 649
Score = 92.8 bits (229), Expect = 1e-17
Identities = 45/89 (50%), Positives = 59/89 (66%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
S EFFPPKTE G NLL RM+RM A +P F +TW AGG+TA TL++A Q + V
Sbjct: 27 SLEFFPPKTEPGKRNLLARMERMCALNPLFITVTWAAGGTTAGKTLELATIAQRELNVPV 86
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
MHLTCTNM + ID+AL+ + ++N+
Sbjct: 87 CMHLTCTNMNKDIIDEALKAARDADIRNI 115
[129][TOP]
>UniRef100_C6HED8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6HED8_AJECH
Length = 713
Score = 92.8 bits (229), Expect = 1e-17
Identities = 50/108 (46%), Positives = 70/108 (64%), Gaps = 2/108 (1%)
Frame = +3
Query: 87 IEKIHEAAAS-DPNKGGFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 260
+EKI + A+ P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIANLPPDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 261 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
A +L++A+ Q +G+ T +HLTCTNM +D AL K+ G++N+
Sbjct: 61 AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNI 108
[130][TOP]
>UniRef100_C5P4Q4 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5P4Q4_COCP7
Length = 711
Score = 92.8 bits (229), Expect = 1e-17
Identities = 50/108 (46%), Positives = 69/108 (63%), Gaps = 2/108 (1%)
Frame = +3
Query: 87 IEKIHEAAASDPNKGG-FSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 260
+EKI A+ P FS EFFPPKT+ G NL R++RM A P F +TWGAGG+T
Sbjct: 1 MEKISNKIAALPEDADYFSLEFFPPKTQMGSANLQARLERMSQALRPLFVTVTWGAGGTT 60
Query: 261 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
A +L++A+ Q +G+ T +HLTCTNM ID AL+ K+ G++N+
Sbjct: 61 ATKSLELAEICQRQLGLTTCLHLTCTNMNRTLIDSALDEAKALGIRNI 108
[131][TOP]
>UniRef100_C1GJU2 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1GJU2_PARBD
Length = 712
Score = 92.8 bits (229), Expect = 1e-17
Identities = 48/108 (44%), Positives = 69/108 (63%), Gaps = 2/108 (1%)
Frame = +3
Query: 87 IEKIHEAAASDPNKGG-FSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 260
+E+I + A+ P FS EFFPPKT G +NL R++RM A P F ++TWGAGGST
Sbjct: 1 MERISDKIAALPQDANYFSLEFFPPKTPMGFLNLKARLERMSQALRPLFVNVTWGAGGST 60
Query: 261 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+L++A+ Q +G+ T +HLTCTNM +DDAL + G++N+
Sbjct: 61 VSKSLELAEMCQRQLGLTTCLHLTCTNMNRTLVDDALAEANALGIRNI 108
[132][TOP]
>UniRef100_C0NTN2 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NTN2_AJECG
Length = 713
Score = 92.8 bits (229), Expect = 1e-17
Identities = 50/108 (46%), Positives = 70/108 (64%), Gaps = 2/108 (1%)
Frame = +3
Query: 87 IEKIHEAAAS-DPNKGGFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 260
+EKI + A+ P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIANLPPDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 261 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
A +L++A+ Q +G+ T +HLTCTNM +D AL K+ G++N+
Sbjct: 61 AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNI 108
[133][TOP]
>UniRef100_A6QT35 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6QT35_AJECN
Length = 712
Score = 92.8 bits (229), Expect = 1e-17
Identities = 50/108 (46%), Positives = 70/108 (64%), Gaps = 2/108 (1%)
Frame = +3
Query: 87 IEKIHEAAAS-DPNKGGFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 260
+EKI + A+ P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIANLPPDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 261 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
A +L++A+ Q +G+ T +HLTCTNM +D AL K+ G++N+
Sbjct: 61 AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNI 108
[134][TOP]
>UniRef100_C1H0K0 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1H0K0_PARBA
Length = 713
Score = 92.0 bits (227), Expect = 2e-17
Identities = 48/108 (44%), Positives = 68/108 (62%), Gaps = 2/108 (1%)
Frame = +3
Query: 87 IEKIHEAAASDPNKGG-FSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 260
+E+I + A+ P FS EFFPPKT G +NL R++RM A P F +TWGAGGST
Sbjct: 1 MERISDKIAALPQDANYFSLEFFPPKTPMGFLNLKTRLERMSQALRPLFVTVTWGAGGST 60
Query: 261 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+L++A+ Q +G+ T +HLTCTNM +DDAL + G++N+
Sbjct: 61 VSKSLELAEMCQRQLGLTTCLHLTCTNMNRTLVDDALAEANALGIRNI 108
[135][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 91.7 bits (226), Expect = 2e-17
Identities = 43/92 (46%), Positives = 67/92 (72%), Gaps = 3/92 (3%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVA---HSPSFCDITWGAGGSTADVTLDIAKKMQNTVG 308
++EFFPP T+ G VNLL+R+ R+ + +P +TWGAGGSTA+ +L++A+++ + +G
Sbjct: 17 NYEFFPPLTDPGFVNLLDRIRRLTSSPFQAPLAVSVTWGAGGSTAEKSLELAQQVVD-MG 75
Query: 309 VETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
VE ++HLTCTNMP +K+D AL K G+ N+
Sbjct: 76 VEVILHLTCTNMPKDKVDFALRRCKDLGISNI 107
[136][TOP]
>UniRef100_C0S8C4 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0S8C4_PARBP
Length = 712
Score = 91.3 bits (225), Expect = 3e-17
Identities = 48/108 (44%), Positives = 68/108 (62%), Gaps = 2/108 (1%)
Frame = +3
Query: 87 IEKIHEAAASDPNKGG-FSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 260
+E+I + A+ P FS EFFPPKT G +NL R++RM A P F +TWGAGGST
Sbjct: 1 MERISDKIAALPQDANYFSLEFFPPKTPMGFLNLKARLERMSQALRPLFVTVTWGAGGST 60
Query: 261 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+L++A+ Q +G+ T +HLTCTNM +DDAL + G++N+
Sbjct: 61 VSKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDDALAEANALGIRNI 108
[137][TOP]
>UniRef100_Q08QG9 Methylenetetrahydrofolate reductase n=1 Tax=Stigmatella aurantiaca
DW4/3-1 RepID=Q08QG9_STIAU
Length = 327
Score = 88.2 bits (217), Expect = 3e-16
Identities = 38/96 (39%), Positives = 63/96 (65%)
Frame = +3
Query: 117 DPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQ 296
+P+ FSFEFFPPKT++G NLL+ ++ + P F +T+GAGGST + TL + +++
Sbjct: 45 NPSNPCFSFEFFPPKTDEGTENLLKTVEELAPLEPGFVSVTYGAGGSTREKTLGLVTRIK 104
Query: 297 NTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T G+E+M HLTC +++ + L+ +++ L NV
Sbjct: 105 QTTGIESMAHLTCVGHTRDELREVLQQLEAAKLDNV 140
[138][TOP]
>UniRef100_B8BVS6 Methylenetetrahydrofolate reductase n=1 Tax=Thalassiosira
pseudonana CCMP1335 RepID=B8BVS6_THAPS
Length = 383
Score = 88.2 bits (217), Expect = 3e-16
Identities = 48/110 (43%), Positives = 69/110 (62%), Gaps = 6/110 (5%)
Frame = +3
Query: 93 KIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPS-FCDITWGAGGSTADV 269
KI + D S E+FPP+T+ GV NL RMDRM+ ++ + + D+TWGAGGSTAD+
Sbjct: 12 KIIDLLQRDTEIAHVSLEYFPPRTDQGVKNLHARMDRMLVNTNALYTDMTWGAGGSTADL 71
Query: 270 TLDIAKKMQNTVGVETMMHLTCTNM-----PVEKIDDALETIKSNGLQNV 404
+L++A T G + MHLTCTNM PV+ + DAL+ G++N+
Sbjct: 72 SLELALHAHKT-GHVSNMHLTCTNMEKDGDPVKAVHDALQQAYDGGIRNI 120
[139][TOP]
>UniRef100_C5DIA7 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5DIA7_LACTC
Length = 660
Score = 88.2 bits (217), Expect = 3e-16
Identities = 45/89 (50%), Positives = 56/89 (62%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
S EFFPPKT+ G NL RM RM A +P F ITWGAGG+TA TL++A Q + V
Sbjct: 36 SLEFFPPKTKLGKQNLTARMTRMTALNPLFITITWGAGGTTAKKTLELATVAQRELNVPV 95
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
MHLTCTN E ID+AL+ ++N+
Sbjct: 96 CMHLTCTNTNKEIIDEALKLAHEADIRNI 124
[140][TOP]
>UniRef100_B6FS52 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium nexile DSM
1787 RepID=B6FS52_9CLOT
Length = 288
Score = 87.8 bits (216), Expect = 3e-16
Identities = 42/109 (38%), Positives = 66/109 (60%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK+ +++ E N+ SFE FPPKT+ G +LE + + A PSF +T+GAGG
Sbjct: 1 MKIKDRLSE------NRVNISFEVFPPKTDAGYGKVLEATEEIAALKPSFISVTYGAGGG 54
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T+ T+ IA +QN +GV ++ HLTC + E++ +E +K G+QN+
Sbjct: 55 TSKNTVKIASHIQNDLGVASLAHLTCASSTKEEVRQVIEQLKEQGIQNI 103
[141][TOP]
>UniRef100_B9XQY3 Methylenetetrahydrofolate reductase n=1 Tax=bacterium Ellin514
RepID=B9XQY3_9BACT
Length = 303
Score = 87.4 bits (215), Expect = 4e-16
Identities = 46/110 (41%), Positives = 70/110 (63%), Gaps = 1/110 (0%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLER-MDRMVAHSPSFCDITWGAGG 254
M+ I I+ AA +D ++ SFEFFPPKT++G LLE+ + ++ P FC +T+GAGG
Sbjct: 7 MQFIRDIY-AAKADAHQPVISFEFFPPKTDEGDRALLEKTIPALLRLKPDFCSVTYGAGG 65
Query: 255 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T D TL I ++Q + TM+HLTC N E++ D +E +S G++N+
Sbjct: 66 GTRDKTLMIVDRIQREHQLPTMLHLTCVNATREQLRDVIEQARSLGVKNI 115
[142][TOP]
>UniRef100_A5KL25 Methylenetetrahydrofolate reductase n=1 Tax=Ruminococcus torques
ATCC 27756 RepID=A5KL25_9FIRM
Length = 289
Score = 87.0 bits (214), Expect = 6e-16
Identities = 40/109 (36%), Positives = 68/109 (62%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK+I+++ E +K SFE FPPKT+ G ++ D M +P+F +T+GAGG
Sbjct: 1 MKIIDRLKE------DKIHISFEVFPPKTDAGFEKVIAATDAMAKLNPAFISVTYGAGGG 54
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T+ T IA +++ +GV ++ HLTC + +E++ D +E +K NG++N+
Sbjct: 55 TSKNTAKIASHIKDDLGVVSLAHLTCASSTIEEVRDVIENLKENGIENI 103
[143][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR2_SCHPO
Length = 641
Score = 87.0 bits (214), Expect = 6e-16
Identities = 47/111 (42%), Positives = 68/111 (61%), Gaps = 2/111 (1%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGF-SFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAG 251
MK+++ I + PN F SFE+FPPKT G+ NL R+ RM + P F +TWG
Sbjct: 1 MKIVDLIDKI----PNGNAFYSFEYFPPKTTVGLENLSSRITRMSRNMMPLFSSVTWGTA 56
Query: 252 GSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
GSTA+V++ +AK ++ + +HLTCTN+ ID ALET K G++N+
Sbjct: 57 GSTAEVSIYLAKMLEQHHKIPACLHLTCTNVDKAIIDKALETAKEYGIRNI 107
[144][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 86.7 bits (213), Expect = 8e-16
Identities = 43/91 (47%), Positives = 57/91 (62%), Gaps = 1/91 (1%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 311
+SFEFFPPKTE G+ NLL R+DRM P F ITWG+ GST TL +A Q V
Sbjct: 1 YSFEFFPPKTEPGLDNLLTRIDRMCRRLDPLFVSITWGSNGSTLSRTLAVASHAQRFACV 60
Query: 312 ETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ ++HL+CT + E+I L KS+G+ N+
Sbjct: 61 DVLLHLSCTGLTREQIGHVLAMAKSSGVHNI 91
[145][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 85.5 bits (210), Expect = 2e-15
Identities = 45/111 (40%), Positives = 63/111 (56%), Gaps = 4/111 (3%)
Frame = +3
Query: 84 VIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTA 263
+IEKIH+ K FS EFFPP+T +G VNL+ R DRM P FCDITW G +
Sbjct: 21 LIEKIHKHIGK--KKKFFSLEFFPPRTPNGAVNLVARFDRMSQGGPLFCDITWHPAGDPS 78
Query: 264 ----DVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ IA N G+ETM+H+TC N+ + + L+ K+ G++N+
Sbjct: 79 GDKETSSCTIASTASNYCGIETMLHMTCANISCDLVLKNLKKAKNLGIRNI 129
[146][TOP]
>UniRef100_Q2ILB5 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter
dehalogenans 2CP-C RepID=Q2ILB5_ANADE
Length = 300
Score = 85.5 bits (210), Expect = 2e-15
Identities = 39/90 (43%), Positives = 57/90 (63%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 314
FSFEFFPPKT+DGV L E ++ + P++ +T+GAGGST T+D+ K+++ VE
Sbjct: 18 FSFEFFPPKTDDGVRGLFETVEALRPLGPAYVSVTYGAGGSTRAKTIDLVKRLKRDAEVE 77
Query: 315 TMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
M H+TC E+I L+ + G+QNV
Sbjct: 78 AMAHVTCVGASREEIAAVLDEVADAGIQNV 107
[147][TOP]
>UniRef100_A7HDS2 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter sp.
Fw109-5 RepID=A7HDS2_ANADF
Length = 300
Score = 85.5 bits (210), Expect = 2e-15
Identities = 39/90 (43%), Positives = 58/90 (64%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 314
FSFEFFPPKT+DGV L E ++ + +P++ +T+GAGGST TL++ K+++ VE
Sbjct: 18 FSFEFFPPKTDDGVRQLFETVEALRPLAPAYVSVTYGAGGSTRQRTLELVKRLKRDTEVE 77
Query: 315 TMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
M HLTC E++ L+ + G+QNV
Sbjct: 78 AMAHLTCVGASREELAAVLDELAEAGIQNV 107
[148][TOP]
>UniRef100_C0C3T3 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium hylemonae
DSM 15053 RepID=C0C3T3_9CLOT
Length = 289
Score = 84.3 bits (207), Expect = 4e-15
Identities = 37/89 (41%), Positives = 59/89 (66%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
SFE FPPKT+ G ++L +++ A PSF +T+GAGG T+ T++IA +QN +GV +
Sbjct: 15 SFEVFPPKTDAGYESVLSATEKIAALKPSFISVTYGAGGGTSKNTVNIASHIQNDLGVVS 74
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ HLTC + E++ +E +K G++NV
Sbjct: 75 LAHLTCASSTKEEVHQVIEKLKEKGIENV 103
[149][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 84.0 bits (206), Expect = 5e-15
Identities = 43/111 (38%), Positives = 62/111 (55%), Gaps = 4/111 (3%)
Frame = +3
Query: 84 VIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW----GAG 251
+I+KI + S +S EFFPP+T+ G VNL+ R DR+ +P F D+TW +G
Sbjct: 26 IIQKIRKRINSGDKF--YSLEFFPPRTDSGGVNLIARFDRLAIGNPLFIDVTWHPKGNSG 83
Query: 252 GSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G +L IA N G+++M+H+TC N E ID L K GL+N+
Sbjct: 84 GDEVTASLTIASAALNFCGLDSMLHMTCINSTTEDIDKYLRKAKKQGLRNI 134
[150][TOP]
>UniRef100_UPI000196BD8E hypothetical protein CATMIT_02257 n=1 Tax=Catenibacterium mitsuokai
DSM 15897 RepID=UPI000196BD8E
Length = 287
Score = 83.6 bits (205), Expect = 6e-15
Identities = 40/109 (36%), Positives = 66/109 (60%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK+I+ ++E +K SFE FPPKT N+L+ +++ + +P+F +T+GAGG
Sbjct: 1 MKIIDLLNE------DKVTLSFEVFPPKTSGRYENVLKAAEKIASLNPNFMSVTYGAGGG 54
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T+ T+ +AK + GVE M HLTC + E ++ +E K NG++N+
Sbjct: 55 TSAHTVALAKDIHEKYGVEVMAHLTCVSSTKEHVESMVEQFKENGIENI 103
[151][TOP]
>UniRef100_Q60CG9 Methylenetetrahydrofolate reductase n=1 Tax=Methylococcus
capsulatus RepID=Q60CG9_METCA
Length = 289
Score = 83.6 bits (205), Expect = 6e-15
Identities = 37/90 (41%), Positives = 56/90 (62%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 314
FSFEFFPPKTE+ NL + ++ P FC +T+GAGGST + T + A ++Q T G+E
Sbjct: 15 FSFEFFPPKTEEATENLRRTLTKLAPLKPRFCSVTFGAGGSTREKTFETALEIQQTTGIE 74
Query: 315 TMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
HL+C I + LE +S+G++++
Sbjct: 75 CAPHLSCIASTRRSIREILEAYRSHGIRHI 104
[152][TOP]
>UniRef100_B4D0K5 Methylenetetrahydrofolate reductase n=1 Tax=Chthoniobacter flavus
Ellin428 RepID=B4D0K5_9BACT
Length = 297
Score = 83.6 bits (205), Expect = 6e-15
Identities = 40/90 (44%), Positives = 57/90 (63%), Gaps = 1/90 (1%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLER-MDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 314
S EFFP KTE+G NLLE+ + +++ P+FC +T+GAGG T D TL I ++Q +
Sbjct: 20 SLEFFPTKTEEGERNLLEKTLPDLMSIKPAFCSVTYGAGGGTRDKTLGIVDRIQRHHNLP 79
Query: 315 TMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
MMHLTC N E++ L+ K G+QN+
Sbjct: 80 AMMHLTCVNSTREELGHVLDEAKGRGIQNI 109
[153][TOP]
>UniRef100_C1XWC8 Methylenetetrahydrofolate reductase n=1 Tax=Meiothermus silvanus
DSM 9946 RepID=C1XWC8_9DEIN
Length = 294
Score = 83.2 bits (204), Expect = 8e-15
Identities = 42/104 (40%), Positives = 61/104 (58%)
Frame = +3
Query: 93 KIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVT 272
KIH A P K FSFEFFPPKTE+G L + + P+F +T+GAGGS T
Sbjct: 2 KIHTQFA--PGKPLFSFEFFPPKTEEGEAQLFRTLHILKPLQPAFVSVTYGAGGSARGKT 59
Query: 273 LDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
++ ++++ VG+E M HLTC E+I + LE ++ G +N+
Sbjct: 60 VEWVERIKREVGLEVMAHLTCVGATREEIGEVLEQLRQVGAENL 103
[154][TOP]
>UniRef100_B8JEQ3 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter
dehalogenans 2CP-1 RepID=B8JEQ3_ANAD2
Length = 300
Score = 82.8 bits (203), Expect = 1e-14
Identities = 37/90 (41%), Positives = 57/90 (63%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 314
FSFEFFPPKT+DGV L E ++ + P++ +T+GAGGST T+++ K+++ VE
Sbjct: 18 FSFEFFPPKTDDGVRGLFETVEALRPLGPAYVSVTYGAGGSTRAKTIELVKRLKRDAEVE 77
Query: 315 TMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
M H+TC ++I L+ + G+QNV
Sbjct: 78 AMAHVTCVGASRDEIAAVLDEVAEAGIQNV 107
[155][TOP]
>UniRef100_B4UHX4 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter sp. K
RepID=B4UHX4_ANASK
Length = 300
Score = 82.8 bits (203), Expect = 1e-14
Identities = 37/90 (41%), Positives = 57/90 (63%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 314
FSFEFFPPKT+DGV L E ++ + P++ +T+GAGGST T+++ K+++ VE
Sbjct: 18 FSFEFFPPKTDDGVRGLFETVEALRPLGPAYVSVTYGAGGSTRAKTIELVKRLKRDAEVE 77
Query: 315 TMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
M H+TC ++I L+ + G+QNV
Sbjct: 78 AMAHVTCVGASRDEIAAVLDEVAEAGIQNV 107
[156][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 81.6 bits (200), Expect = 2e-14
Identities = 44/94 (46%), Positives = 56/94 (59%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T G VNL+ R DRM + P F DITW G GS + ++ IA N
Sbjct: 60 FSLEFFPPRTSSGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY 119
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+E+++HLTC N EKI D L K GL+N+
Sbjct: 120 CGLESVLHLTCCNQTKEKITDHLNKAKRLGLKNI 153
[157][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 81.6 bits (200), Expect = 2e-14
Identities = 36/67 (53%), Positives = 47/67 (70%)
Frame = +3
Query: 204 MVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIK 383
M A P F DITW AGG T+D+T ++ K Q +G+ET MHLTCTNMP EK+D AL+ K
Sbjct: 1 MRALGPEFIDITWNAGGRTSDLTSEMVKTCQGLIGIETCMHLTCTNMPREKVDTALKEAK 60
Query: 384 SNGLQNV 404
+G +N+
Sbjct: 61 EHGCRNI 67
[158][TOP]
>UniRef100_B0N2P6 Methylenetetrahydrofolate reductase n=2 Tax=Bacteria
RepID=B0N2P6_9FIRM
Length = 296
Score = 81.3 bits (199), Expect = 3e-14
Identities = 38/110 (34%), Positives = 66/110 (60%), Gaps = 1/110 (0%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDG-VVNLLERMDRMVAHSPSFCDITWGAGG 254
MK+I+ +H SFE FPPK DG + ++ + +D + P F +T+GAGG
Sbjct: 1 MKIIDLLHRRPT-------LSFEIFPPKNHDGDISSIYQTIDELAKLKPDFISVTYGAGG 53
Query: 255 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
ST + T++IA K++N +E + HL+C + E++ L+++K+N ++NV
Sbjct: 54 STTENTVEIASKIKNEYSIEAVAHLSCIDATPEQLIRVLDSLKANNIENV 103
[159][TOP]
>UniRef100_A4HQF9 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania braziliensis
RepID=A4HQF9_LEIBR
Length = 309
Score = 81.3 bits (199), Expect = 3e-14
Identities = 39/101 (38%), Positives = 62/101 (61%), Gaps = 2/101 (1%)
Frame = +3
Query: 108 AASDPNKGGFSFEFFPPKTEDGVVNLLE-RMDRMVAHSPSFCDITWGAGGSTADVTLDIA 284
AA D NK S+EF+PP++E N ++ ++ + SP F D+TWGAGG T++ T+ +
Sbjct: 10 AAEDANKWYTSYEFYPPRSEKAEENFMKVQIPNFMRQSPVFLDLTWGAGGRTSETTMRLC 69
Query: 285 KKMQNTV-GVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
K +QN MH+TCTNM + I + L+ K +G++N+
Sbjct: 70 KDLQNAYPDTPINMHITCTNMSHDLIKETLDFAKEHGIRNI 110
[160][TOP]
>UniRef100_C4FKN7 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
yellowstonense SS-5 RepID=C4FKN7_9AQUI
Length = 292
Score = 80.5 bits (197), Expect = 5e-14
Identities = 41/109 (37%), Positives = 60/109 (55%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK+I+K+ S SFEFFPPKTE+ L E + + +P+F +T+GAGGS
Sbjct: 1 MKIIDKLKNTKIS------ISFEFFPPKTEEAEKTLFETISNLQPLNPTFVSVTYGAGGS 54
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T + T DI KK+ + M HLTC ++I L+ K G++N+
Sbjct: 55 TREKTRDIVKKIHEETNLTVMAHLTCIGHSKQEILSILDDYKKIGIENI 103
[161][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 80.1 bits (196), Expect = 7e-14
Identities = 41/100 (41%), Positives = 55/100 (55%), Gaps = 4/100 (4%)
Frame = +3
Query: 117 DPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQ 296
+ N FS EFFPP+TE G NL+ R DRM A P F DITW G + + K+
Sbjct: 27 ESNDPFFSLEFFPPRTEQGAANLIGRFDRMRAGGPLFVDITWHPAGDPGSDKITSSTKIA 86
Query: 297 NTV----GVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
TV G++TM+H+TC E I LE K+ G++N+
Sbjct: 87 GTVLNYCGLDTMLHMTCVKQTKETIKKNLEKTKNLGIRNI 126
[162][TOP]
>UniRef100_C1DUH1 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
azorense Az-Fu1 RepID=C1DUH1_SULAA
Length = 291
Score = 79.7 bits (195), Expect = 9e-14
Identities = 39/109 (35%), Positives = 64/109 (58%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK+++K+ + S SFEFFPPKT++ +L + ++ + +P+F +T+GAGGS
Sbjct: 1 MKIVDKLKKEKVS------ISFEFFPPKTKELEDSLFKTIEELKPINPTFVSVTYGAGGS 54
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T + T DI KK+ + M HLTC ++I LE K+ G++N+
Sbjct: 55 TREKTRDIVKKIHEETNLTVMAHLTCVGHSKQEIKQILEDYKNIGIENI 103
[163][TOP]
>UniRef100_O67422 5,10-methylenetetrahydrofolate reductase n=1 Tax=Aquifex aeolicus
RepID=METF_AQUAE
Length = 296
Score = 79.0 bits (193), Expect = 2e-13
Identities = 40/95 (42%), Positives = 59/95 (62%), Gaps = 2/95 (2%)
Frame = +3
Query: 126 KGGFS--FEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQN 299
KG FS FEFFPPKTE+G L E + ++ +P+F +T+GAGGST D T +I +K+
Sbjct: 9 KGVFSISFEFFPPKTEEGERQLFETIRKLEKLNPTFVSVTYGAGGSTRDRTRNIVQKIHE 68
Query: 300 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ M HLTC E++ D L+ K+ G++N+
Sbjct: 69 ETNLTVMAHLTCIAHTREELIDILQDYKNIGIENI 103
[164][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 78.6 bits (192), Expect = 2e-13
Identities = 41/94 (43%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 65 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTALNY 124
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC E+I L K GL+N+
Sbjct: 125 CGLETILHMTCCQQRQEEISGHLHRAKQLGLKNI 158
[165][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 78.6 bits (192), Expect = 2e-13
Identities = 41/94 (43%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTALNY 159
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC E+I L K GL+N+
Sbjct: 160 CGLETILHMTCCQQRQEEISGHLHRAKQLGLKNI 193
[166][TOP]
>UniRef100_B2V845 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
sp. YO3AOP1 RepID=B2V845_SULSY
Length = 291
Score = 78.6 bits (192), Expect = 2e-13
Identities = 40/109 (36%), Positives = 60/109 (55%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK+I+K+ S SFEFFPPKTE+ L E + + +P+F +T+GAGGS
Sbjct: 1 MKIIDKLKNTKVS------ISFEFFPPKTEEAEKTLFETISNLQPLNPTFVSVTYGAGGS 54
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T + T DI KK+ + M HLTC ++I L+ + G++N+
Sbjct: 55 TREKTRDIVKKIHEETKLTVMAHLTCIGHSKQEILSILDDYEKIGIENI 103
[167][TOP]
>UniRef100_A3DBL1 Methylenetetrahydrofolate reductase n=3 Tax=Clostridium
thermocellum RepID=A3DBL1_CLOTH
Length = 291
Score = 78.6 bits (192), Expect = 2e-13
Identities = 34/89 (38%), Positives = 56/89 (62%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
SFE FPPK + + ++ +++ P F +T+GAGGS D T++IA K++N G+E+
Sbjct: 15 SFEIFPPKLDTPIESIFGTLEQFKELKPDFISVTYGAGGSAKDRTIEIASKIKNEYGIES 74
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
M HLTC E+ID L +++ + L+N+
Sbjct: 75 MAHLTCVGHSKEEIDALLTSMREHNLENI 103
[168][TOP]
>UniRef100_B6JY06 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6JY06_SCHJY
Length = 626
Score = 78.6 bits (192), Expect = 2e-13
Identities = 41/110 (37%), Positives = 65/110 (59%), Gaps = 1/110 (0%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 254
MK+ E++ + D + +SFEFFPPKT G+ NL RM RM P F +TW + G
Sbjct: 1 MKISEQLEQLPKDDIH---YSFEFFPPKTTIGLDNLTVRMKRMSKTMFPLFSSVTWSSAG 57
Query: 255 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
S+A +L + +Q+ GV + +H+TC+N+ E I L+ K+ G++N+
Sbjct: 58 SSAAESLALCASLQSKFGVTSCLHMTCSNVDKESIKKNLDQAKAYGIRNI 107
[169][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 78.2 bits (191), Expect = 3e-13
Identities = 40/94 (42%), Positives = 56/94 (59%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T +G VNL+ R DRM A P + D+TW G GS + ++ IA N
Sbjct: 83 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNY 142
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC +E+I L K GL+N+
Sbjct: 143 CGLETILHMTCCRQRLEEITGHLHKAKQLGLKNI 176
[170][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 78.2 bits (191), Expect = 3e-13
Identities = 40/94 (42%), Positives = 56/94 (59%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T +G VNL+ R DRM A P + D+TW G GS + ++ IA N
Sbjct: 101 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNY 160
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC +E+I L K GL+N+
Sbjct: 161 CGLETILHMTCCRQRLEEITGHLHKAKQLGLKNI 194
[171][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 78.2 bits (191), Expect = 3e-13
Identities = 41/94 (43%), Positives = 56/94 (59%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 83 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 142
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC +E+I L K GL+N+
Sbjct: 143 CGLETILHMTCCCQRLEEITGHLHKAKQLGLKNI 176
[172][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 78.2 bits (191), Expect = 3e-13
Identities = 41/94 (43%), Positives = 56/94 (59%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 101 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 160
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC +E+I L K GL+N+
Sbjct: 161 CGLETILHMTCCCQRLEEITGHLHKAKQLGLKNI 194
[173][TOP]
>UniRef100_Q8CJA7 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Mus musculus
RepID=Q8CJA7_MOUSE
Length = 157
Score = 78.2 bits (191), Expect = 3e-13
Identities = 41/94 (43%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC E+I L K GL+N+
Sbjct: 119 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNI 152
[174][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 78.2 bits (191), Expect = 3e-13
Identities = 41/94 (43%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 159
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC E+I L K GL+N+
Sbjct: 160 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNI 193
[175][TOP]
>UniRef100_B2KFL5 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Mus musculus
RepID=B2KFL5_MOUSE
Length = 194
Score = 78.2 bits (191), Expect = 3e-13
Identities = 41/94 (43%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC E+I L K GL+N+
Sbjct: 119 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNI 152
[176][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 78.2 bits (191), Expect = 3e-13
Identities = 41/94 (43%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 159
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC E+I L K GL+N+
Sbjct: 160 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNI 193
[177][TOP]
>UniRef100_A2A7F9 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Mus musculus
RepID=A2A7F9_MOUSE
Length = 194
Score = 78.2 bits (191), Expect = 3e-13
Identities = 41/94 (43%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC E+I L K GL+N+
Sbjct: 119 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNI 152
[178][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 78.2 bits (191), Expect = 3e-13
Identities = 41/94 (43%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 159
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC E+I L K GL+N+
Sbjct: 160 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNI 193
[179][TOP]
>UniRef100_B8DJ94 Methylenetetrahydrofolate reductase n=1 Tax=Desulfovibrio vulgaris
str. 'Miyazaki F' RepID=B8DJ94_DESVM
Length = 291
Score = 78.2 bits (191), Expect = 3e-13
Identities = 42/109 (38%), Positives = 63/109 (57%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK+ ++I AA++ P +S EFFPPK + ++R+ A P F +T+GAGGS
Sbjct: 1 MKIRDRI--AASTRPF---YSLEFFPPKERENWPGFFATVERLKALDPLFASVTYGAGGS 55
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T D TL+I ++N +G+E M HLTC E+I D L ++ + NV
Sbjct: 56 TQDNTLEITSHLKNVMGLEPMAHLTCVGATRERIADYLRRLREVNVDNV 104
[180][TOP]
>UniRef100_B4S8Y1 Methylenetetrahydrofolate reductase n=1 Tax=Prosthecochloris
aestuarii DSM 271 RepID=B4S8Y1_PROA2
Length = 296
Score = 78.2 bits (191), Expect = 3e-13
Identities = 36/90 (40%), Positives = 53/90 (58%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 314
FSFEFFPPK D L + ++ +PS+ +T+GAGGST T D+ K++ G+
Sbjct: 15 FSFEFFPPKKNDDWDRLFRTISELIPFNPSYVSVTYGAGGSTRTRTHDLVTKIRKETGLT 74
Query: 315 TMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ HLTC ++I D L T ++NG+ NV
Sbjct: 75 VVSHLTCICSTKDEISDILSTYENNGITNV 104
[181][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 78.2 bits (191), Expect = 3e-13
Identities = 40/94 (42%), Positives = 56/94 (59%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T +G VNL+ R DRM A P + D+TW G GS + ++ IA N
Sbjct: 60 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNY 119
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC +E+I L K GL+N+
Sbjct: 120 CGLETILHMTCCRQRLEEITGHLHKAKQLGLKNI 153
[182][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 78.2 bits (191), Expect = 3e-13
Identities = 40/94 (42%), Positives = 56/94 (59%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T +G VNL+ R DRM A P + D+TW G GS + ++ IA N
Sbjct: 90 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNY 149
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC +E+I L K GL+N+
Sbjct: 150 CGLETILHMTCCRQRLEEITGHLHKAKQLGLKNI 183
[183][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 78.2 bits (191), Expect = 3e-13
Identities = 41/94 (43%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC E+I L K GL+N+
Sbjct: 119 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNI 152
[184][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 78.2 bits (191), Expect = 3e-13
Identities = 41/94 (43%), Positives = 56/94 (59%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 60 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 119
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC +E+I L K GL+N+
Sbjct: 120 CGLETILHMTCCCQRLEEITGHLHKAKQLGLKNI 153
[185][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 77.8 bits (190), Expect = 4e-13
Identities = 41/94 (43%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T G VNL+ R DRM + P F D+TW G GS + ++ IA N
Sbjct: 54 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVNF 113
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC N E I L+ K GL+N+
Sbjct: 114 CGLETLLHMTCCNQTKEDITKHLQKAKRLGLKNI 147
[186][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 77.8 bits (190), Expect = 4e-13
Identities = 37/94 (39%), Positives = 53/94 (56%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTA----DVTLDIAKKMQNT 302
FS EFFPP+T +G VNLL DR+ + P FCD+TW G + ++ IA N
Sbjct: 12 FSVEFFPPRTPNGAVNLLGTFDRLASACPLFCDVTWHPAGDPSGDKDTSSMTIASTALNY 71
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ETM+H+TC N + L K+ G++N+
Sbjct: 72 CGLETMLHMTCANQTKASVTKNLHKAKTLGIRNI 105
[187][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 77.4 bits (189), Expect = 5e-13
Identities = 42/94 (44%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 64 FSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 123
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+E+++HLTC N +KI L K GL+N+
Sbjct: 124 CGLESILHLTCCNQTKDKITGYLGKAKRLGLKNI 157
[188][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 77.4 bits (189), Expect = 5e-13
Identities = 42/94 (44%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 64 FSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 123
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+E+++HLTC N +KI L K GL+N+
Sbjct: 124 CGLESILHLTCCNQTKDKITGYLGKAKRLGLKNI 157
[189][TOP]
>UniRef100_B0SH77 Methylenetetrahydrofolate reductase n=2 Tax=Leptospira biflexa
serovar Patoc RepID=B0SH77_LEPBA
Length = 295
Score = 77.4 bits (189), Expect = 5e-13
Identities = 34/89 (38%), Positives = 53/89 (59%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
SFEFFPPK E+ +L + + +P++ +T+GAGGST +T D+ K+QN G+
Sbjct: 15 SFEFFPPKNEEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRHLTHDLVVKLQNETGLTI 74
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ HLTC E+I D L+ +G+ N+
Sbjct: 75 VSHLTCVGSTKEEIGDILKRYDKSGIHNI 103
[190][TOP]
>UniRef100_A9KQY7 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium
phytofermentans ISDg RepID=A9KQY7_CLOPH
Length = 286
Score = 77.4 bits (189), Expect = 5e-13
Identities = 36/91 (39%), Positives = 54/91 (59%), Gaps = 1/91 (1%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD-VTLDIAKKMQNTVGV 311
FS E FPPK + V ++ + + +P F +T+GAGG+ AD T DIA +Q+ G+
Sbjct: 14 FSLEVFPPKKDSPVESIYRVLGELTKLNPDFISVTYGAGGNAADHTTCDIASYIQSNYGI 73
Query: 312 ETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ + HLTC N E +D LE +KS G+ N+
Sbjct: 74 DALTHLTCVNSTKEDMDTTLEYLKSQGIMNI 104
[191][TOP]
>UniRef100_A3JC11 Methylenetetrahydrofolate reductase n=1 Tax=Marinobacter sp. ELB17
RepID=A3JC11_9ALTE
Length = 318
Score = 77.4 bits (189), Expect = 5e-13
Identities = 39/93 (41%), Positives = 54/93 (58%)
Frame = +3
Query: 126 KGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 305
K FSFEFFPPKTE G + L D + A +P F +T+GAGGST D TL+ +
Sbjct: 37 KRRFSFEFFPPKTEQGKIKLQGVRDELAAVNPDFFSVTFGAGGSTRDRTLETVFSLHQQ- 95
Query: 306 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ T HL+C +I + L+T K+NG+ +
Sbjct: 96 GISTAPHLSCVGGTRAEISELLDTYKANGINRI 128
[192][TOP]
>UniRef100_Q1D7X5 Methylenetetrahydrofolate reductase n=1 Tax=Myxococcus xanthus DK
1622 RepID=Q1D7X5_MYXXD
Length = 290
Score = 77.0 bits (188), Expect = 6e-13
Identities = 35/96 (36%), Positives = 57/96 (59%)
Frame = +3
Query: 117 DPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQ 296
+P+ FSFEFFPP+T++G NLL+ ++ + P F +T GAGGST T+++ +++
Sbjct: 8 NPSDPCFSFEFFPPRTDEGEANLLKALEDLATLQPGFVSVTEGAGGSTRAKTVELVLRIK 67
Query: 297 NTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+E M HLTC ++ LE + + + NV
Sbjct: 68 QEAGIEAMAHLTCGGHSPAELRTVLERLSAAKVDNV 103
[193][TOP]
>UniRef100_A1VEZ2 Methylenetetrahydrofolate reductase n=3 Tax=Desulfovibrio vulgaris
RepID=A1VEZ2_DESVV
Length = 291
Score = 77.0 bits (188), Expect = 6e-13
Identities = 40/109 (36%), Positives = 59/109 (54%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK+ E I + + +S EFFPPK + ++R+ A P F +T+GAGG
Sbjct: 1 MKIAEAIERQS-----RPFYSLEFFPPKEREQWPAFFATVERLKAMDPVFASVTYGAGGG 55
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T D TLDI ++N +G+E M HLTC E+I L ++ G++NV
Sbjct: 56 TQDNTLDITAHLKNALGLEPMAHLTCVGATRERIAGFLARLREQGVENV 104
[194][TOP]
>UniRef100_A6NZH7 Methylenetetrahydrofolate reductase n=1 Tax=Bacteroides capillosus
ATCC 29799 RepID=A6NZH7_9BACE
Length = 286
Score = 77.0 bits (188), Expect = 6e-13
Identities = 39/109 (35%), Positives = 61/109 (55%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK+I+ + + +K SFE FPPKT D ++ + + A P F +T+GAGG
Sbjct: 1 MKIIDILSQ------DKVTLSFEVFPPKTSDSYESVAKATQEIAALKPDFMSVTYGAGGG 54
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T+D T+ IA +++ GVE + HLTC + E + L +K +G+ NV
Sbjct: 55 TSDYTVGIAAGIRDKYGVEPLAHLTCASSTREHVHQVLGKLKESGISNV 103
[195][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 76.6 bits (187), Expect = 8e-13
Identities = 41/94 (43%), Positives = 54/94 (57%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T G VNL+ R DRM + P F D+TW G GS + ++ IA N
Sbjct: 54 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMVIASAAVNF 113
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC N E I L K GL+N+
Sbjct: 114 CGLETILHMTCCNQTKEDITKHLHKAKHLGLKNI 147
[196][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 76.6 bits (187), Expect = 8e-13
Identities = 42/94 (44%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T G VNL+ R DRM + P F DITW G GS + ++ IA N
Sbjct: 64 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY 123
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+E+++HLTC N +KI L K GL+N+
Sbjct: 124 CGLESILHLTCCNQTKDKITGYLGKAKHLGLKNI 157
[197][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 76.6 bits (187), Expect = 8e-13
Identities = 41/94 (43%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNY 118
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC + E+I L K GL+N+
Sbjct: 119 CGLETILHMTCCHQSREEITGHLNKAKQLGLKNI 152
[198][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 76.6 bits (187), Expect = 8e-13
Identities = 41/94 (43%), Positives = 54/94 (57%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T G VNL+ R DRM + P F D+TW G GS + ++ IA N
Sbjct: 54 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMVIASAAVNF 113
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC N E I L K GL+N+
Sbjct: 114 CGLETILHMTCCNQTKEDITKHLHKAKHLGLKNI 147
[199][TOP]
>UniRef100_C5RR04 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium
cellulovorans 743B RepID=C5RR04_CLOCL
Length = 285
Score = 76.6 bits (187), Expect = 8e-13
Identities = 34/94 (36%), Positives = 56/94 (59%)
Frame = +3
Query: 123 NKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNT 302
N+ FS E FPPK D N++ +D + F +T+GAGGS+ D T+ ++KK+++
Sbjct: 9 NRQSFSVELFPPKKTDSFDNIINTLDNLNGLDIDFVSVTYGAGGSSRDNTVKLSKKIKSE 68
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+E + HLTC N ++I L+ +K N L+N+
Sbjct: 69 YNLEVITHLTCINSKKDEIASLLDEMKENNLENI 102
[200][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 76.6 bits (187), Expect = 8e-13
Identities = 36/80 (45%), Positives = 53/80 (66%), Gaps = 2/80 (2%)
Frame = +3
Query: 171 GVVNLLERMDRMVAHSPSFCDITWGAGG--STADVTLDIAKKMQNTVGVETMMHLTCTNM 344
GV NL ER+DRM P + D+TWGAGG S+++ T +I + G++ MMHLTCT+
Sbjct: 2 GVQNLYERLDRMAELGPMWIDVTWGAGGASSSSNKTFEICRNALTYHGLDVMMHLTCTHQ 61
Query: 345 PVEKIDDALETIKSNGLQNV 404
VE+ID+ L+ K G++N+
Sbjct: 62 SVEEIDEVLDKCKEVGIRNI 81
[201][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 76.6 bits (187), Expect = 8e-13
Identities = 41/94 (43%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNY 118
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC + E+I L K GL+N+
Sbjct: 119 CGLETILHMTCCHQSREEITGHLNKAKQLGLKNI 152
[202][TOP]
>UniRef100_Q2SLT5 Methylenetetrahydrofolate reductase n=1 Tax=Hahella chejuensis KCTC
2396 RepID=Q2SLT5_HAHCH
Length = 287
Score = 76.3 bits (186), Expect = 1e-12
Identities = 37/93 (39%), Positives = 53/93 (56%)
Frame = +3
Query: 126 KGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 305
K FSFEFFPPKT +G+ L D++ P F +T+GAGGST + T+D +
Sbjct: 8 KRRFSFEFFPPKTPEGMEKLQVVRDKLAKRKPDFFSVTYGAGGSTRERTIDTVLTLHRQ- 66
Query: 306 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ T HL+C E I + L+ +SNG+Q +
Sbjct: 67 GISTAPHLSCIGATKESIGELLDLYRSNGIQRI 99
[203][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 76.3 bits (186), Expect = 1e-12
Identities = 38/91 (41%), Positives = 58/91 (63%), Gaps = 1/91 (1%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 311
+SFEFFPPKTE G+ NLL R+DRM P F D+TWG+ ++A T+ +A Q +GV
Sbjct: 41 YSFEFFPPKTEAGLDNLLTRIDRMAQRLDPLFIDVTWGSDKTSAR-TMALASHAQKYLGV 99
Query: 312 ETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ ++HL+C M +++ L+ K G+ N+
Sbjct: 100 DVLLHLSCQGMTRDQLIRVLDQAKVLGIHNI 130
[204][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 76.3 bits (186), Expect = 1e-12
Identities = 36/80 (45%), Positives = 52/80 (65%), Gaps = 2/80 (2%)
Frame = +3
Query: 171 GVVNLLERMDRMVAHSPSFCDITWGAGGSTA--DVTLDIAKKMQNTVGVETMMHLTCTNM 344
GV NL ER+DRM P + D+TWGAGGS++ + T +I + G++ MMHLTCT
Sbjct: 2 GVQNLYERLDRMAELGPMWIDVTWGAGGSSSSSNKTFEICRNALTYHGLDVMMHLTCTQQ 61
Query: 345 PVEKIDDALETIKSNGLQNV 404
VE+ID+ L+ K G++N+
Sbjct: 62 SVEEIDEVLDKCKEVGIRNI 81
[205][TOP]
>UniRef100_A4IC95 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania infantum
RepID=A4IC95_LEIIN
Length = 309
Score = 76.3 bits (186), Expect = 1e-12
Identities = 37/101 (36%), Positives = 63/101 (62%), Gaps = 2/101 (1%)
Frame = +3
Query: 108 AASDPNKGGFSFEFFPPKTEDGVVNLLERM-DRMVAHSPSFCDITWGAGGSTADVTLDIA 284
AA D +K S+E +PP++E ++++ + + SP F D+TWGAGG T+D T+ +
Sbjct: 10 AAEDVSKWYTSYELYPPRSEKAEEDMMKVLVPNFMRQSPVFLDLTWGAGGRTSDTTMRLC 69
Query: 285 KKMQNTV-GVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
K +Q+ MH+TCTN P I++AL+ K++G++N+
Sbjct: 70 KDLQHAYPDTPINMHITCTNTPKGLINEALDFAKTHGIRNI 110
[206][TOP]
>UniRef100_A4RH85 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RH85_MAGGR
Length = 662
Score = 76.3 bits (186), Expect = 1e-12
Identities = 38/79 (48%), Positives = 54/79 (68%), Gaps = 1/79 (1%)
Frame = +3
Query: 171 GVVNLLERMDRMV-AHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMP 347
G NL +R+DRM A P F ++TWGAGGSTA +L++A+ Q + + T +HLTCTNM
Sbjct: 2 GFSNLRDRLDRMARALRPLFVNVTWGAGGSTAQKSLELAEICQRELALTTCLHLTCTNMS 61
Query: 348 VEKIDDALETIKSNGLQNV 404
+ ID ALE K+ G++N+
Sbjct: 62 RKLIDKALEDAKALGIRNI 80
[207][TOP]
>UniRef100_A8UU31 Methylenetetrahydrofolate reductase n=1 Tax=Hydrogenivirga sp.
128-5-R1-1 RepID=A8UU31_9AQUI
Length = 298
Score = 75.9 bits (185), Expect = 1e-12
Identities = 35/89 (39%), Positives = 54/89 (60%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
SFEFFPPK E+G L + + + P+F +T+GAGGST D T ++ K++ VG+
Sbjct: 15 SFEFFPPKGEEGERQLFQTIKELEELKPTFVSVTYGAGGSTRDRTRNVVKRIHEEVGLTV 74
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
M HLTC E++ + LE + G++N+
Sbjct: 75 MAHLTCIAHTREELIEILEDYRGIGIENI 103
[208][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Canis lupus familiaris RepID=UPI00005A03BF
Length = 780
Score = 75.5 bits (184), Expect = 2e-12
Identities = 41/94 (43%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 102 FSLEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 161
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC E+I L K GL+N+
Sbjct: 162 CGLETILHMTCCCQSREQITGYLHKAKRLGLKNI 195
[209][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 75.5 bits (184), Expect = 2e-12
Identities = 41/94 (43%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 102 FSLEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 161
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC E+I L K GL+N+
Sbjct: 162 CGLETILHMTCCCQSREQITGYLHKAKRLGLKNI 195
[210][TOP]
>UniRef100_B5CM26 Methylenetetrahydrofolate reductase n=1 Tax=Ruminococcus lactaris
ATCC 29176 RepID=B5CM26_9FIRM
Length = 289
Score = 75.5 bits (184), Expect = 2e-12
Identities = 35/109 (32%), Positives = 64/109 (58%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK+I++++E ++ SFE FPPKT+ G N+ D + PS+ +T+GAGG
Sbjct: 1 MKIIDRLNE------DRINISFEVFPPKTDAGFANVQRATDEIAKLDPSYISVTYGAGGG 54
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T+ T IA +++ + V ++ HLTC + E++ + + +K G++N+
Sbjct: 55 TSKNTAKIASHIKDDLHVLSLAHLTCASSTKEEVREVIRNLKELGIENI 103
[211][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 75.5 bits (184), Expect = 2e-12
Identities = 42/114 (36%), Positives = 61/114 (53%), Gaps = 5/114 (4%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
+K+ ++I A D + FS EFFPP+T G NL+ R +RMV P F DITW G
Sbjct: 30 VKLADRIE--AKIDRGERWFSLEFFPPRTPQGAANLISRFERMVQGGPMFMDITWHPAGD 87
Query: 258 TAD-----VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ ++ IA N VG ETM+H++C N + I L+ K G++N+
Sbjct: 88 PGNSDKETSSMSIACAALNYVGHETMLHMSCCNSTKDDIRRHLDKAKELGIRNI 141
[212][TOP]
>UniRef100_Q04NW1 Methylenetetrahydrofolate reductase n=2 Tax=Leptospira
borgpetersenii serovar Hardjo-bovis RepID=Q04NW1_LEPBJ
Length = 290
Score = 75.1 bits (183), Expect = 2e-12
Identities = 38/109 (34%), Positives = 60/109 (55%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK + +I+ +A +SFEFFPPKT+DG + L+ + + P F +T+GAGGS
Sbjct: 1 MKKVSEIYGSAKGPV----YSFEFFPPKTQDGDLKLMGTVKELARLDPDFVTVTYGAGGS 56
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T D T I ++ T+ H TC ++I L+ I+S+G+ N+
Sbjct: 57 TRDKTAQILSEISKNYSFPTVSHFTCVGANQDQIFKTLKEIRSSGIVNL 105
[213][TOP]
>UniRef100_C7IBI3 5,10-methylenetetrahydrofolate reductase n=1 Tax=Clostridium
papyrosolvens DSM 2782 RepID=C7IBI3_9CLOT
Length = 286
Score = 75.1 bits (183), Expect = 2e-12
Identities = 34/90 (37%), Positives = 60/90 (66%), Gaps = 1/90 (1%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD-VTLDIAKKMQNTVGVE 314
SFE FPPK + + ++ E + + SP F +T+GAGGS+ + T++IAKK+++ G+E
Sbjct: 15 SFEIFPPKRDSELKDIDETLAILSKLSPDFISVTFGAGGSSNNNKTIEIAKKIKHQYGIE 74
Query: 315 TMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T++HLTC+ ++ID + + NG++N+
Sbjct: 75 TLVHLTCSGYTKQEIDSFISILSENGIENI 104
[214][TOP]
>UniRef100_A8TTR8 Methylenetetrahydrofolate reductase n=1 Tax=alpha proteobacterium
BAL199 RepID=A8TTR8_9PROT
Length = 288
Score = 75.1 bits (183), Expect = 2e-12
Identities = 34/89 (38%), Positives = 52/89 (58%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
SFEFFPPK E G + L E +DR+ + P F +T+GAGGST + T I +++ G+E
Sbjct: 8 SFEFFPPKDEAGEIKLWETLDRLAPYGPRFVSVTYGAGGSTRERTSRIVTRIKRETGLEP 67
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
HLTC +++D+ G+++V
Sbjct: 68 AAHLTCVGATCDEVDEVARGWWDAGIRHV 96
[215][TOP]
>UniRef100_C6BWS6 Methylenetetrahydrofolate reductase n=1 Tax=Desulfovibrio
salexigens DSM 2638 RepID=C6BWS6_DESAD
Length = 290
Score = 74.7 bits (182), Expect = 3e-12
Identities = 38/111 (34%), Positives = 60/111 (54%), Gaps = 2/111 (1%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGG--FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAG 251
MK+I+ I NK G S EFFPPK + E +D++ +P F +T+GAG
Sbjct: 1 MKIIDLI--------NKNGQFISLEFFPPKDRESWPKFFEVVDKLKVLNPLFASVTYGAG 52
Query: 252 GSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G T D +L+I K+M+ G+E + HLTC E I + + ++ ++N+
Sbjct: 53 GGTQDNSLEIVKRMKQDAGIEPLAHLTCVGASPENISEFVSALQEADVENI 103
[216][TOP]
>UniRef100_A4J6K4 Methylenetetrahydrofolate reductase n=1 Tax=Desulfotomaculum
reducens MI-1 RepID=A4J6K4_DESRM
Length = 288
Score = 74.7 bits (182), Expect = 3e-12
Identities = 33/89 (37%), Positives = 52/89 (58%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
SFE FPPK+ V + E ++ ++ P F +T+GAGGS+ D T +IA ++N +E
Sbjct: 15 SFEIFPPKSTSPVETIYETLEGLIKLEPGFISVTYGAGGSSRDRTKEIAATIKNRYKIEA 74
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ HLTC V +ID L ++ ++NV
Sbjct: 75 LAHLTCVGQAVNEIDQILNELQEENIENV 103
[217][TOP]
>UniRef100_C1SKU9 Methylenetetrahydrofolate reductase n=1 Tax=Denitrovibrio
acetiphilus DSM 12809 RepID=C1SKU9_9BACT
Length = 284
Score = 74.7 bits (182), Expect = 3e-12
Identities = 34/94 (36%), Positives = 54/94 (57%)
Frame = +3
Query: 123 NKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNT 302
+K SFEFFPPK ++ L E + ++ ++P F +T+GAGGST + TL+ K+M+
Sbjct: 9 DKRSVSFEFFPPKKQESEQVLFETIKKLRRYNPEFVSVTYGAGGSTTEKTLEWTKRMKED 68
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
MMH TC ID A +++K + + N+
Sbjct: 69 HDYSVMMHFTCIGADAAVIDSATQSLKESRVDNI 102
[218][TOP]
>UniRef100_B1C148 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium spiroforme
DSM 1552 RepID=B1C148_9FIRM
Length = 296
Score = 74.7 bits (182), Expect = 3e-12
Identities = 35/110 (31%), Positives = 64/110 (58%), Gaps = 1/110 (0%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDG-VVNLLERMDRMVAHSPSFCDITWGAGG 254
MK+I+ +H+ SFE FPPK DG + ++ + +D + P F +T+GAGG
Sbjct: 1 MKIIDLLHKRPT-------LSFEIFPPKNYDGDISSIYQTIDELSKLKPDFISVTYGAGG 53
Query: 255 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
ST T++IA K++N +E + HL+C + +++ ++ +K N ++N+
Sbjct: 54 STTKNTVEIASKIKNDYNIEAVAHLSCIDASPKQLIKIIDALKENKIENI 103
[219][TOP]
>UniRef100_B0NAG8 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium scindens
ATCC 35704 RepID=B0NAG8_EUBSP
Length = 301
Score = 74.7 bits (182), Expect = 3e-12
Identities = 33/94 (35%), Positives = 57/94 (60%)
Frame = +3
Query: 123 NKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNT 302
N SFE FPPKT+ G + +++ A PSF +T+GAGG T+ T+ IA +++N
Sbjct: 22 NSPHVSFEVFPPKTDAGYEGVRAATEKIAALRPSFISVTYGAGGGTSRNTVRIASQIKND 81
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+GV ++ HLTC + +++ + +K G++N+
Sbjct: 82 LGVTSLAHLTCVSSTKDEVHGVIGQLKEQGIENI 115
[220][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 74.3 bits (181), Expect = 4e-12
Identities = 40/94 (42%), Positives = 54/94 (57%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T G VNL+ R D+M A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAQGAVNLISRFDQMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC E+I L K GL+N+
Sbjct: 119 CGLETVLHMTCCRQSREEITGYLHKAKRLGLKNI 152
[221][TOP]
>UniRef100_B3E425 Methylenetetrahydrofolate reductase n=1 Tax=Geobacter lovleyi SZ
RepID=B3E425_GEOLS
Length = 290
Score = 74.3 bits (181), Expect = 4e-12
Identities = 33/89 (37%), Positives = 53/89 (59%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
S E+FPPK + ++R+ + +P F +T+GAGGS D TL+I +MQ +G+ET
Sbjct: 15 SVEYFPPKERQDWPAFFKVVERLASLNPLFASVTYGAGGSNQDATLEIVTQMQQQLGLET 74
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
M HLTC +++ L+ + G+QN+
Sbjct: 75 MAHLTCVGAQAGRLNRFLDDLSKVGIQNI 103
[222][TOP]
>UniRef100_Q1MYH5 Methylenetetrahydrofolate reductase n=1 Tax=Bermanella marisrubri
RepID=Q1MYH5_9GAMM
Length = 278
Score = 74.3 bits (181), Expect = 4e-12
Identities = 37/89 (41%), Positives = 51/89 (57%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
SFEFFP KTE+G L D++ P F +T+GAGGST D T+D+ KM N +GV T
Sbjct: 7 SFEFFPTKTEEGTKKLYATRDKLAELKPDFFSVTFGAGGSTRDHTMDVVTKM-NGMGVGT 65
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
HL+C ++I L T N ++ +
Sbjct: 66 APHLSCIGQSKDEIKQLLSTYADNKVERI 94
[223][TOP]
>UniRef100_B0G1G9 Methylenetetrahydrofolate reductase n=1 Tax=Dorea formicigenerans
ATCC 27755 RepID=B0G1G9_9FIRM
Length = 293
Score = 74.3 bits (181), Expect = 4e-12
Identities = 32/89 (35%), Positives = 55/89 (61%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
SFE FPPKT+ G ++L +++ A PSF +T+GAGG T+ T+ IA +++ GV +
Sbjct: 17 SFEIFPPKTDAGYDSVLSAAEKIAALKPSFISVTYGAGGGTSKNTVSIASHIKDDFGVTS 76
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ HLTC + E++ ++ +K + N+
Sbjct: 77 LAHLTCVSSTREEVHRVIDKLKEKNIDNI 105
[224][TOP]
>UniRef100_A7AYB6 Methylenetetrahydrofolate reductase n=1 Tax=Ruminococcus gnavus
ATCC 29149 RepID=A7AYB6_RUMGN
Length = 289
Score = 74.3 bits (181), Expect = 4e-12
Identities = 34/109 (31%), Positives = 61/109 (55%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK+I+++ E SFE FPPKT+ G ++ + M P F +T+GAGG
Sbjct: 1 MKIIDRLREDGIH------ISFEIFPPKTDAGYDKVIRAAEEMAGLKPEFISVTYGAGGG 54
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T+ T IA +++ + VE++ HLTC + +++ + ++K G++N+
Sbjct: 55 TSKNTAKIASYIKHDLHVESLAHLTCASSTKDEVRSVIASLKEQGIENI 103
[225][TOP]
>UniRef100_A8Q9P3 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8Q9P3_MALGO
Length = 515
Score = 74.3 bits (181), Expect = 4e-12
Identities = 35/62 (56%), Positives = 41/62 (66%)
Frame = +3
Query: 219 PSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQ 398
P F DITW AGG T+D+T + K +Q GVET MHLTCTNMP KI+ AL K G +
Sbjct: 6 PEFVDITWNAGGRTSDMTTQLVKTVQTYFGVETCMHLTCTNMPRSKIEVALREAKEFGCR 65
Query: 399 NV 404
NV
Sbjct: 66 NV 67
[226][TOP]
>UniRef100_UPI000194E904 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH), partial n=1 Tax=Taeniopygia guttata
RepID=UPI000194E904
Length = 345
Score = 73.9 bits (180), Expect = 5e-12
Identities = 39/94 (41%), Positives = 56/94 (59%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T + VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 62 FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY 121
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC + ++I L+ K GL+N+
Sbjct: 122 CGLETILHMTCCHQTRDEITGHLQKAKRLGLKNI 155
[227][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 73.9 bits (180), Expect = 5e-12
Identities = 39/94 (41%), Positives = 56/94 (59%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T + VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 62 FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY 121
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC + ++I L+ K GL+N+
Sbjct: 122 CGLETIVHMTCCHQTKDEITGHLQKAKRLGLKNI 155
[228][TOP]
>UniRef100_B8GP49 Methylenetetrahydrofolate reductase n=1 Tax=Thioalkalivibrio sp.
HL-EbGR7 RepID=B8GP49_THISH
Length = 286
Score = 73.9 bits (180), Expect = 5e-12
Identities = 35/90 (38%), Positives = 52/90 (57%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 314
FSFEFFPPKT++G L + + + P F +T+GAGGST TLD ++Q E
Sbjct: 11 FSFEFFPPKTDEGAEKLRKAREALAELKPKFFSVTYGAGGSTQARTLDTVLEIQRDARFE 70
Query: 315 TMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
HL+C E I + LE ++NG++++
Sbjct: 71 AAPHLSCIGSTREHIREILELYRNNGIRHI 100
[229][TOP]
>UniRef100_C5EJM1 Methylenetetrahydrofolate reductase n=1 Tax=Clostridiales bacterium
1_7_47FAA RepID=C5EJM1_9FIRM
Length = 292
Score = 73.9 bits (180), Expect = 5e-12
Identities = 39/94 (41%), Positives = 59/94 (62%), Gaps = 1/94 (1%)
Frame = +3
Query: 126 KGGFSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFCDITWGAGGSTADVTLDIAKKMQNT 302
K SFE FPPKTED N +E+ + +A P+F +T+GAGG T+D T+ IA ++
Sbjct: 11 KPTLSFEVFPPKTEDN-YNTVEKAAKEIAKLKPAFMSVTYGAGGGTSDYTVGIASDIKE- 68
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
GV + HLTC + EK+ L+ +K++G++NV
Sbjct: 69 YGVTPLAHLTCVSSTREKVQGVLKELKAHGIENV 102
[230][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 73.6 bits (179), Expect = 7e-12
Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 302
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + ++ IA +
Sbjct: 54 FSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMIIANTAVDY 113
Query: 303 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+ET++H+TC+ ++I L K GL+N+
Sbjct: 114 CGLETVLHMTCSQQNRDEITSHLHKAKRLGLKNI 147
[231][TOP]
>UniRef100_Q8EY55 Methylenetetrahydrofolate reductase n=1 Tax=Leptospira interrogans
RepID=Q8EY55_LEPIN
Length = 310
Score = 73.6 bits (179), Expect = 7e-12
Identities = 38/109 (34%), Positives = 61/109 (55%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK + +I+ +A +SFEFFPPKT +G L+E + + +P F +T+GAGGS
Sbjct: 18 MKKVSEIYGSAKGPV----YSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGS 73
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T D T+ I ++ T+ H TC +I + L+ I+S+G+ N+
Sbjct: 74 TRDKTVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNL 122
[232][TOP]
>UniRef100_Q75G11 Methylenetetrahydrofolate reductase n=2 Tax=Leptospira interrogans
RepID=Q75G11_LEPIC
Length = 310
Score = 73.6 bits (179), Expect = 7e-12
Identities = 38/109 (34%), Positives = 61/109 (55%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
MK + +I+ +A +SFEFFPPKT +G L+E + + +P F +T+GAGGS
Sbjct: 18 MKKVSEIYGSAKGPV----YSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGS 73
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T D T+ I ++ T+ H TC +I + L+ I+S+G+ N+
Sbjct: 74 TRDKTVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNL 122
[233][TOP]
>UniRef100_C0B744 Methylenetetrahydrofolate reductase n=1 Tax=Coprococcus comes ATCC
27758 RepID=C0B744_9FIRM
Length = 288
Score = 73.6 bits (179), Expect = 7e-12
Identities = 35/109 (32%), Positives = 62/109 (56%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M++I+KI SFE FPPKT+ G ++L+ D + +PSF +T+GAGG
Sbjct: 1 MRIIDKIKADGVH------ISFEVFPPKTDAGFESVLKATDGIAELTPSFISVTYGAGGG 54
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T+ T+ IA ++N + + + HLTC + E++ + ++ G++N+
Sbjct: 55 TSKNTVKIASHIKNDLKIPALAHLTCVSSTKEEVHKVIGQLQKEGIENI 103
[234][TOP]
>UniRef100_A8S2A1 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium bolteae
ATCC BAA-613 RepID=A8S2A1_9CLOT
Length = 285
Score = 73.6 bits (179), Expect = 7e-12
Identities = 35/93 (37%), Positives = 53/93 (56%)
Frame = +3
Query: 126 KGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 305
K SFE FPPKTED ++ + + PSF +T+GAGG T++ T+ IA ++
Sbjct: 11 KPTLSFEVFPPKTEDAYDSVEKAAAEIAKLKPSFMSVTYGAGGGTSEYTVGIASAIKEEY 70
Query: 306 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
GV + HLTC + EK+ L ++ G++NV
Sbjct: 71 GVTPLAHLTCVSSTREKVHHVLGELRERGIENV 103
[235][TOP]
>UniRef100_Q4Q0B9 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania major
RepID=Q4Q0B9_LEIMA
Length = 309
Score = 73.6 bits (179), Expect = 7e-12
Identities = 37/101 (36%), Positives = 60/101 (59%), Gaps = 2/101 (1%)
Frame = +3
Query: 108 AASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFCDITWGAGGSTADVTLDIA 284
AA D +K S+E +PP++E ++++ + H SP F D+TWGAGG T+ T+ +
Sbjct: 10 AAEDASKWNTSYELYPPRSEKAEEDMMKVLVPNFMHQSPVFLDLTWGAGGRTSGTTMRLC 69
Query: 285 KKMQNT-VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
K +Q+ MH+TCTN P I + LE K++G++N+
Sbjct: 70 KDLQHAHPDTPINMHITCTNTPKGLIKETLEFAKTHGIRNI 110
[236][TOP]
>UniRef100_UPI0001794577 hypothetical protein CLOSPO_03313 n=1 Tax=Clostridium sporogenes
ATCC 15579 RepID=UPI0001794577
Length = 336
Score = 73.2 bits (178), Expect = 9e-12
Identities = 33/91 (36%), Positives = 54/91 (59%), Gaps = 1/91 (1%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD-VTLDIAKKMQNTVGV 311
FSFE FPPK V + E ++ + +P F +T+GAGGS D T +++ ++N G+
Sbjct: 55 FSFEIFPPKATSSVKTIYETLEELKDLTPDFISVTYGAGGSLKDNKTCELSSLVKNKYGI 114
Query: 312 ETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
E + HLTC N + ID ++ +K N ++N+
Sbjct: 115 EALAHLTCINSTKDDIDLIIKELKENNIKNI 145
[237][TOP]
>UniRef100_A1BH63 Methylenetetrahydrofolate reductase n=1 Tax=Chlorobium
phaeobacteroides DSM 266 RepID=A1BH63_CHLPD
Length = 289
Score = 73.2 bits (178), Expect = 9e-12
Identities = 35/90 (38%), Positives = 50/90 (55%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 314
FSFEFFPPK E+ L + + + +PS+ +T+GAGGST T D+ ++Q G+
Sbjct: 15 FSFEFFPPKKEEEWNTLFATIASLTSLNPSYVSVTYGAGGSTRSKTHDLVTRIQKETGIT 74
Query: 315 TMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ HLTC E+ LE NG+ NV
Sbjct: 75 VVSHLTCVCSDREETSSILENYLENGINNV 104
[238][TOP]
>UniRef100_C0FIZ9 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium sp. M62/1
RepID=C0FIZ9_9CLOT
Length = 287
Score = 73.2 bits (178), Expect = 9e-12
Identities = 37/93 (39%), Positives = 55/93 (59%)
Frame = +3
Query: 126 KGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 305
K SFE FPPK ED ++ E R+ P+F +T+GAGG T+ T+DIA ++N
Sbjct: 11 KPTLSFEVFPPKAEDKYDSVEEAAIRIARLKPAFMSVTYGAGGGTSKYTVDIASSIKNQ- 69
Query: 306 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
GV + HLTC + E++ L +K+ G++NV
Sbjct: 70 GVNALAHLTCVSSTKEEVRRVLGELKTRGIENV 102
[239][TOP]
>UniRef100_C6BZ56 Methylenetetrahydrofolate reductase n=1 Tax=Desulfovibrio
salexigens DSM 2638 RepID=C6BZ56_DESAD
Length = 293
Score = 72.8 bits (177), Expect = 1e-11
Identities = 36/109 (33%), Positives = 61/109 (55%)
Frame = +3
Query: 78 MKVIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 257
M+V + I+EA FSFEFFPPK + +ER R+ A P F +T+GAGG+
Sbjct: 1 MQVAQNINEAGQF------FSFEFFPPKDKSTWPVFMERAARLAALKPLFASVTYGAGGT 54
Query: 258 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ D +L+I ++ +G++ + HLTC + ID+ + + G+ ++
Sbjct: 55 SHDNSLEICSLLKKDMGIDILAHLTCVGASEQSIDEFVSRLCETGVSDI 103
[240][TOP]
>UniRef100_C3WZX4 Methylenetetrahydrofolate reductase n=1 Tax=Fusobacterium sp. 7_1
RepID=C3WZX4_9FUSO
Length = 288
Score = 72.8 bits (177), Expect = 1e-11
Identities = 32/89 (35%), Positives = 54/89 (60%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
SFE FPP + G+ + +D + P + +T+GAGG+T T++IA +++ GVE+
Sbjct: 15 SFEVFPPNDKVGLEQVYNCLDILSLEKPDYISVTYGAGGNTKGKTVEIADRIKRQNGVES 74
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ HLTC E+ID LE ++ N ++N+
Sbjct: 75 LAHLTCIGAKKEEIDRVLEDLEKNNIENI 103
[241][TOP]
>UniRef100_C3WGW3 Methylenetetrahydrofolate reductase n=1 Tax=Fusobacterium sp.
2_1_31 RepID=C3WGW3_9FUSO
Length = 288
Score = 72.8 bits (177), Expect = 1e-11
Identities = 32/89 (35%), Positives = 55/89 (61%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
SFE FPP + G+ + +D + P + +T+GAGG+T T++IA +++N GVE+
Sbjct: 15 SFEVFPPNDKVGLEQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTVEIADRIKNQNGVES 74
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ HLTC E+ID LE ++ + ++N+
Sbjct: 75 VAHLTCIGAKKEEIDKVLEDLEKHNIENI 103
[242][TOP]
>UniRef100_A5TSW7 Methylenetetrahydrofolate reductase n=1 Tax=Fusobacterium nucleatum
subsp. polymorphum ATCC 10953 RepID=A5TSW7_FUSNP
Length = 288
Score = 72.8 bits (177), Expect = 1e-11
Identities = 32/89 (35%), Positives = 55/89 (61%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
SFE FPP + G+ + +D + P + +T+GAGG+T T++IA ++++ GVE+
Sbjct: 15 SFEVFPPNDKVGLEQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTVEIANRIKSQNGVES 74
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ HLTC E+ID LE ++ N ++N+
Sbjct: 75 VAHLTCIGAKKEEIDRVLEDLEKNNIENI 103
[243][TOP]
>UniRef100_UPI0001B534F1 5,10-methylenetetrahydrofolate reductase n=1 Tax=Fusobacterium sp.
D11 RepID=UPI0001B534F1
Length = 289
Score = 72.4 bits (176), Expect = 1e-11
Identities = 32/89 (35%), Positives = 54/89 (60%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
SFE FPP + G+ + +D + P + +T+GAGG+T T++IA +++ GVE+
Sbjct: 15 SFEVFPPNDKVGLEQVYNCLDILSIEKPDYISVTYGAGGNTKGRTVEIADRIKRQNGVES 74
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ HLTC E+ID LE ++ N ++N+
Sbjct: 75 LAHLTCIGAKKEEIDRVLEDLEKNNIENI 103
[244][TOP]
>UniRef100_C6JIG2 Methylenetetrahydrofolate reductase n=1 Tax=Fusobacterium varium
ATCC 27725 RepID=C6JIG2_FUSVA
Length = 293
Score = 72.4 bits (176), Expect = 1e-11
Identities = 31/89 (34%), Positives = 54/89 (60%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
SFE FPP + + ++ +D + P F +T+GAGG+T T++IA K++N +E
Sbjct: 15 SFEVFPPNSIYSLEDVYSSIDELAKLQPDFISVTYGAGGATRGNTVEIASKIKNNNKIEA 74
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ HLTC +IDD L+ +++N ++N+
Sbjct: 75 LAHLTCLGAKKNEIDDILKQLRANNIENI 103
[245][TOP]
>UniRef100_B1BN89 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium perfringens
C str. JGS1495 RepID=B1BN89_CLOPE
Length = 292
Score = 72.4 bits (176), Expect = 1e-11
Identities = 32/91 (35%), Positives = 57/91 (62%), Gaps = 1/91 (1%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS-TADVTLDIAKKMQNTVGV 311
FSFE FPPK + N+ + ++ + P F +T+GAGG+ T++ T++++ ++N +
Sbjct: 14 FSFEVFPPKESTSIKNIYKTLEEIQELKPDFISVTYGAGGNFTSNRTIELSSIIKNKYNL 73
Query: 312 ETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
ET+ HLTC ++I+ L +KS G++NV
Sbjct: 74 ETLAHLTCIGAKRKEIEQTLNILKSKGIENV 104
[246][TOP]
>UniRef100_A3RPV8 Methylenetetrahydrofolate reductase n=2 Tax=Ralstonia solanacearum
RepID=A3RPV8_RALSO
Length = 276
Score = 72.4 bits (176), Expect = 1e-11
Identities = 36/90 (40%), Positives = 52/90 (57%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 314
FSFEFFPPKT +G L ++ P F +T+GAGG+T TLD ++Q G+E
Sbjct: 6 FSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQRE-GIE 64
Query: 315 TMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
HL+C E I D L+T ++NG++ +
Sbjct: 65 AAPHLSCVGSSRESIRDILDTYRANGIRRL 94
[247][TOP]
>UniRef100_Q3A3T2 Methylenetetrahydrofolate reductase n=1 Tax=Pelobacter carbinolicus
DSM 2380 RepID=Q3A3T2_PELCD
Length = 301
Score = 72.0 bits (175), Expect = 2e-11
Identities = 32/90 (35%), Positives = 53/90 (58%)
Frame = +3
Query: 135 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 314
FSFEFFPPKT+ L E + ++ + P F +T+GAGGST + T D+ ++ + ++
Sbjct: 14 FSFEFFPPKTDKAAERLYETIRQLESLHPHFTSVTYGAGGSTRERTHDLVMRIHESSSLD 73
Query: 315 TMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
+ HLTC + P ++I L+ G+ N+
Sbjct: 74 PIPHLTCVSSPEQEIHQILKRYAEAGISNI 103
[248][TOP]
>UniRef100_C0QT51 Methylenetetrahydrofolate reductase n=1 Tax=Persephonella marina
EX-H1 RepID=C0QT51_PERMH
Length = 293
Score = 72.0 bits (175), Expect = 2e-11
Identities = 34/89 (38%), Positives = 52/89 (58%)
Frame = +3
Query: 138 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 317
SFEFFPPKT +G L + + +P+F +T+GAGGST + T+ + K++ +
Sbjct: 15 SFEFFPPKTPEGEDQLFRTIKDLEKLNPTFVSVTYGAGGSTRERTIRVVKRIHEQCNLTV 74
Query: 318 MMHLTCTNMPVEKIDDALETIKSNGLQNV 404
M HLTC ++I D L+ K G+QN+
Sbjct: 75 MAHLTCIGHSKKEIYDILKGYKDIGIQNI 103
[249][TOP]
>UniRef100_Q0YRM1 Methylenetetrahydrofolate reductase n=1 Tax=Chlorobium ferrooxidans
DSM 13031 RepID=Q0YRM1_9CHLB
Length = 328
Score = 72.0 bits (175), Expect = 2e-11
Identities = 38/107 (35%), Positives = 60/107 (56%)
Frame = +3
Query: 84 VIEKIHEAAASDPNKGGFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTA 263
++++I +AA K FSFEFFPPK ++ L + + + +PS+ +T+GAGGST
Sbjct: 41 LVKEILDAAV----KPVFSFEFFPPKKDEEWETLFKTIAALSPLNPSYVSVTYGAGGSTR 96
Query: 264 DVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
T D+ K+Q G+ + HLTC E+ L+ + NG+ NV
Sbjct: 97 SRTHDLVTKIQRETGLTVVSHLTCICSDREETGSILQNYRDNGINNV 143
[250][TOP]
>UniRef100_B0NXP2 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium sp. SS2/1
RepID=B0NXP2_9CLOT
Length = 295
Score = 72.0 bits (175), Expect = 2e-11
Identities = 34/95 (35%), Positives = 57/95 (60%), Gaps = 1/95 (1%)
Frame = +3
Query: 123 NKGGFSFEFFPPKTEDG-VVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQN 299
NK SFE FPPK ++G + ++ ++ + SP F +T+GAGGST T++IA +++
Sbjct: 9 NKSTISFEVFPPKNKEGNISSIYSTIEGLAKLSPDFISVTYGAGGSTKGKTVEIASVIKH 68
Query: 300 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNV 404
G+E++ HL+C + E I E +K G+ N+
Sbjct: 69 EYGIESVAHLSCISSTKEDIKYECERLKEAGIDNI 103