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[1][TOP]
>UniRef100_B2DDA8 Topoisomerase I n=1 Tax=Catharanthus roseus RepID=B2DDA8_CATRO
Length = 910
Score = 164 bits (416), Expect = 2e-39
Identities = 78/93 (83%), Positives = 88/93 (94%)
Frame = -1
Query: 480 KSPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVA 301
K+ DGK K+NL+ E+LEKKI+QT+AKIEKM+RD +TKEDLKTVALGTS+INYLDPRITVA
Sbjct: 818 KNADGKPKRNLNPESLEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVA 877
Query: 300 WCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
WCKRHEVPIEKIFN+SLLAKFTWAMDVDP FRF
Sbjct: 878 WCKRHEVPIEKIFNKSLLAKFTWAMDVDPSFRF 910
[2][TOP]
>UniRef100_Q9FJ79 DNA topoisomerase I n=1 Tax=Arabidopsis thaliana RepID=Q9FJ79_ARATH
Length = 917
Score = 160 bits (406), Expect = 3e-38
Identities = 74/90 (82%), Positives = 85/90 (94%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
DGK+K+NL+ EALEKKI QT KIEKM+RDM+TKED+KTVALGTS+INY+DPRITVAWCK
Sbjct: 822 DGKRKRNLTPEALEKKIMQTQGKIEKMERDMQTKEDMKTVALGTSKINYMDPRITVAWCK 881
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
RH+VPIEKIFN+SLLAKF WAMDVDP+FRF
Sbjct: 882 RHDVPIEKIFNKSLLAKFAWAMDVDPEFRF 911
[3][TOP]
>UniRef100_Q8RXI5 Putative DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=Q8RXI5_ARATH
Length = 232
Score = 160 bits (406), Expect = 3e-38
Identities = 74/90 (82%), Positives = 85/90 (94%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
DGK+K+NL+ EALEKKI QT KIEKM+RDM+TKED+KTVALGTS+INY+DPRITVAWCK
Sbjct: 137 DGKRKRNLTPEALEKKIMQTQGKIEKMERDMQTKEDMKTVALGTSKINYMDPRITVAWCK 196
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
RH+VPIEKIFN+SLLAKF WAMDVDP+FRF
Sbjct: 197 RHDVPIEKIFNKSLLAKFAWAMDVDPEFRF 226
[4][TOP]
>UniRef100_B9I1A0 Predicted protein (Fragment) n=1 Tax=Populus trichocarpa
RepID=B9I1A0_POPTR
Length = 860
Score = 160 bits (404), Expect = 5e-38
Identities = 76/93 (81%), Positives = 85/93 (91%)
Frame = -1
Query: 480 KSPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVA 301
K DGK+K+NL+ EA+EKKI+ T+ KIEKM+ MKTKEDLKTVALGTS+INYLDPRITVA
Sbjct: 768 KDADGKQKRNLTPEAIEKKIATTNQKIEKMELSMKTKEDLKTVALGTSKINYLDPRITVA 827
Query: 300 WCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
WCKRHEVPIEKIFN+SLLAKFTWAMDVDP FRF
Sbjct: 828 WCKRHEVPIEKIFNKSLLAKFTWAMDVDPQFRF 860
[5][TOP]
>UniRef100_UPI000198447D PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI000198447D
Length = 883
Score = 159 bits (401), Expect = 1e-37
Identities = 75/93 (80%), Positives = 84/93 (90%)
Frame = -1
Query: 480 KSPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVA 301
K DGK KKN++ E LE+KI+QT+ KIEKM+RDMKTKEDLKTVALGTS+INYLDPRI+VA
Sbjct: 791 KDSDGKPKKNMTPEVLERKIAQTNTKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVA 850
Query: 300 WCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
WCKR EVPIEKIFN+SLLAKF WAMDVDP FRF
Sbjct: 851 WCKRQEVPIEKIFNKSLLAKFAWAMDVDPSFRF 883
[6][TOP]
>UniRef100_A7PX10 Chromosome chr12 scaffold_36, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7PX10_VITVI
Length = 789
Score = 159 bits (401), Expect = 1e-37
Identities = 75/93 (80%), Positives = 84/93 (90%)
Frame = -1
Query: 480 KSPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVA 301
K DGK KKN++ E LE+KI+QT+ KIEKM+RDMKTKEDLKTVALGTS+INYLDPRI+VA
Sbjct: 697 KDSDGKPKKNMTPEVLERKIAQTNTKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVA 756
Query: 300 WCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
WCKR EVPIEKIFN+SLLAKF WAMDVDP FRF
Sbjct: 757 WCKRQEVPIEKIFNKSLLAKFAWAMDVDPSFRF 789
[7][TOP]
>UniRef100_B9SSQ1 DNA topoisomerase type I, putative n=1 Tax=Ricinus communis
RepID=B9SSQ1_RICCO
Length = 891
Score = 158 bits (400), Expect = 2e-37
Identities = 75/93 (80%), Positives = 85/93 (91%)
Frame = -1
Query: 480 KSPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVA 301
K DGK+K+NLS E +EKKI+ T+ +IEKM+ +MKTKEDLKTVALGTS+INYLDPRITVA
Sbjct: 799 KDADGKQKRNLSPENIEKKIASTNQRIEKMELNMKTKEDLKTVALGTSKINYLDPRITVA 858
Query: 300 WCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
WCKRHEVPIEKIFN+SLLAKFTWAMDVDP FRF
Sbjct: 859 WCKRHEVPIEKIFNKSLLAKFTWAMDVDPQFRF 891
[8][TOP]
>UniRef100_B2DDA6 Topoisomerase I n=1 Tax=Ophiorrhiza japonica RepID=B2DDA6_9GENT
Length = 927
Score = 157 bits (398), Expect = 3e-37
Identities = 74/93 (79%), Positives = 85/93 (91%)
Frame = -1
Query: 480 KSPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVA 301
K DGK K+NL+ EALE+K++Q +AKIEKM+RD +TKEDLKTVALGTS+INYLDPRITVA
Sbjct: 835 KGADGKPKRNLNPEALERKMAQINAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVA 894
Query: 300 WCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
WCKRHEVPIEKIFN+SLLAKF W+MDVDP FRF
Sbjct: 895 WCKRHEVPIEKIFNKSLLAKFAWSMDVDPSFRF 927
[9][TOP]
>UniRef100_B9GJH5 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9GJH5_POPTR
Length = 877
Score = 156 bits (395), Expect = 6e-37
Identities = 74/93 (79%), Positives = 85/93 (91%)
Frame = -1
Query: 480 KSPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVA 301
K DGK+K++L+ EA+EKKI+ T+ KIEKM+ MKTKEDLKTVALGTS+INYLDPRITVA
Sbjct: 785 KGADGKQKRSLTPEAIEKKIATTNQKIEKMEMAMKTKEDLKTVALGTSKINYLDPRITVA 844
Query: 300 WCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
WCKRHEVPI+KIFN+SLLAKFTWAMDVDP FRF
Sbjct: 845 WCKRHEVPIDKIFNKSLLAKFTWAMDVDPQFRF 877
[10][TOP]
>UniRef100_Q84ZL5 Os08g0154600 protein n=1 Tax=Oryza sativa Japonica Group
RepID=Q84ZL5_ORYSJ
Length = 916
Score = 156 bits (394), Expect = 8e-37
Identities = 74/90 (82%), Positives = 81/90 (90%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
DGK K+NL+ EA EKKISQ KIEKM+ D K KEDLKTVALGTS+INYLDPRITVAWCK
Sbjct: 827 DGKPKRNLAPEAFEKKISQIETKIEKMEMDKKIKEDLKTVALGTSKINYLDPRITVAWCK 886
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
RHEVPIEKIFN+SL+AKF+WAMDVDPDFRF
Sbjct: 887 RHEVPIEKIFNKSLIAKFSWAMDVDPDFRF 916
[11][TOP]
>UniRef100_A2YRB7 Putative uncharacterized protein n=1 Tax=Oryza sativa Indica Group
RepID=A2YRB7_ORYSI
Length = 916
Score = 156 bits (394), Expect = 8e-37
Identities = 74/90 (82%), Positives = 81/90 (90%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
DGK K+NL+ EA EKKISQ KIEKM+ D K KEDLKTVALGTS+INYLDPRITVAWCK
Sbjct: 827 DGKPKRNLAPEAFEKKISQIETKIEKMEMDKKIKEDLKTVALGTSKINYLDPRITVAWCK 886
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
RHEVPIEKIFN+SL+AKF+WAMDVDPDFRF
Sbjct: 887 RHEVPIEKIFNKSLIAKFSWAMDVDPDFRF 916
[12][TOP]
>UniRef100_Q9XGL1 DNA topoisomerase I n=1 Tax=Daucus carota RepID=Q9XGL1_DAUCA
Length = 909
Score = 155 bits (392), Expect = 1e-36
Identities = 72/93 (77%), Positives = 85/93 (91%)
Frame = -1
Query: 480 KSPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVA 301
K DGK K+N++ EA+EKKI+QT+ KIEKM+RD +TKEDLKTVALGTS+INYLDPRITVA
Sbjct: 817 KGSDGKTKRNMNPEAIEKKIAQTNVKIEKMERDKETKEDLKTVALGTSKINYLDPRITVA 876
Query: 300 WCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
WCKR+EVPIEK+FN+SLLAKF WAMDV+P FRF
Sbjct: 877 WCKRYEVPIEKMFNKSLLAKFAWAMDVEPSFRF 909
[13][TOP]
>UniRef100_B2DDA7 Topoisomerase I n=1 Tax=Camptotheca acuminata RepID=B2DDA7_CAMAC
Length = 894
Score = 154 bits (388), Expect = 4e-36
Identities = 71/90 (78%), Positives = 83/90 (92%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
DGK K+NL+ EALE+KI QT+AKIEKM+RD +TKE LKT+ALGTS+I+YLDPRITVAWCK
Sbjct: 805 DGKPKRNLTPEALERKIGQTNAKIEKMERDKETKEGLKTIALGTSKISYLDPRITVAWCK 864
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
RHEVPIEK+FN+SLLAKF W+MDVDP FRF
Sbjct: 865 RHEVPIEKVFNKSLLAKFAWSMDVDPSFRF 894
[14][TOP]
>UniRef100_B2DDA5 Topoisomerase I n=1 Tax=Ophiorrhiza liukiuensis RepID=B2DDA5_9GENT
Length = 926
Score = 154 bits (388), Expect = 4e-36
Identities = 72/93 (77%), Positives = 84/93 (90%)
Frame = -1
Query: 480 KSPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVA 301
K DG+ K+NL+ E+LE+KI+QT+AKIEKM+RD KTKEDLK VAL TS+I+YLDPRITVA
Sbjct: 834 KGADGEPKRNLNPESLERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVA 893
Query: 300 WCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
WCKRHEVPIEKIFN+SLLAKF W+MDVDP FRF
Sbjct: 894 WCKRHEVPIEKIFNKSLLAKFAWSMDVDPSFRF 926
[15][TOP]
>UniRef100_B2DDA4 Topoisomerase I n=1 Tax=Ophiorrhiza pumila RepID=B2DDA4_9GENT
Length = 926
Score = 152 bits (383), Expect = 1e-35
Identities = 72/93 (77%), Positives = 83/93 (89%)
Frame = -1
Query: 480 KSPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVA 301
K DG+ K+NL+ EALE+KI+QT+AKIEKM+RD KTKEDLK VAL TS+I+YLDPRITVA
Sbjct: 834 KGDDGEPKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVA 893
Query: 300 WCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
WCKR EVPIEK+FN+SLLAKF WAMDVDP FRF
Sbjct: 894 WCKRQEVPIEKMFNKSLLAKFAWAMDVDPSFRF 926
[16][TOP]
>UniRef100_C5YGY1 Putative uncharacterized protein Sb07g003610 n=1 Tax=Sorghum bicolor
RepID=C5YGY1_SORBI
Length = 921
Score = 151 bits (381), Expect = 2e-35
Identities = 70/90 (77%), Positives = 81/90 (90%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
+GK+K+NL+ EA+EKKI+ KI+KM+ D K KEDLKTVALGTS+INYLDPRITVAWCK
Sbjct: 832 EGKQKRNLAPEAIEKKIAMVEGKIDKMEMDKKIKEDLKTVALGTSKINYLDPRITVAWCK 891
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
RHEVPIEKIFN+SL+AKF WAMDVDPDFRF
Sbjct: 892 RHEVPIEKIFNKSLIAKFGWAMDVDPDFRF 921
[17][TOP]
>UniRef100_A7QDA6 Chromosome undetermined scaffold_80, whole genome shotgun sequence
n=1 Tax=Vitis vinifera RepID=A7QDA6_VITVI
Length = 857
Score = 150 bits (380), Expect = 3e-35
Identities = 73/93 (78%), Positives = 84/93 (90%)
Frame = -1
Query: 480 KSPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVA 301
K DGK++ NL+ EALE+KI+QT+AKIEKM+RD TKEDLKTVALGTS+INYLDPRI+VA
Sbjct: 766 KDADGKRR-NLTPEALERKIAQTNAKIEKMERDKDTKEDLKTVALGTSKINYLDPRISVA 824
Query: 300 WCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
WCKR EVPIEK+FN+SLLAKF WAMDV PDFRF
Sbjct: 825 WCKRQEVPIEKVFNKSLLAKFAWAMDVPPDFRF 857
[18][TOP]
>UniRef100_C6KE75 DNA topoisomerase I n=1 Tax=Zea mays RepID=C6KE75_MAIZE
Length = 904
Score = 148 bits (373), Expect = 2e-34
Identities = 68/90 (75%), Positives = 80/90 (88%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
+GK K+NL+ EA++KK++ KIEKM+ D + KEDLKTVALGTS+INYLDPRITVAWCK
Sbjct: 815 EGKPKRNLAPEAIQKKVATLEGKIEKMEMDKRIKEDLKTVALGTSKINYLDPRITVAWCK 874
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
RHEVPIEKIFN+SLLAKF WAMDVDP+FRF
Sbjct: 875 RHEVPIEKIFNKSLLAKFVWAMDVDPEFRF 904
[19][TOP]
>UniRef100_B7ZWU7 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=B7ZWU7_MAIZE
Length = 574
Score = 148 bits (373), Expect = 2e-34
Identities = 68/90 (75%), Positives = 80/90 (88%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
+GK K+NL+ EA++KK++ KIEKM+ D + KEDLKTVALGTS+INYLDPRITVAWCK
Sbjct: 485 EGKPKRNLAPEAIQKKVATLEGKIEKMEMDKRIKEDLKTVALGTSKINYLDPRITVAWCK 544
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
RHEVPIEKIFN+SLLAKF WAMDVDP+FRF
Sbjct: 545 RHEVPIEKIFNKSLLAKFVWAMDVDPEFRF 574
[20][TOP]
>UniRef100_Q8RX06 Putative DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=Q8RX06_ARATH
Length = 514
Score = 147 bits (370), Expect = 5e-34
Identities = 70/90 (77%), Positives = 79/90 (87%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
DGKK ++L A EKKI+Q AKIEKM+RDM TKEDLKTVALGTS+INYLDPRITVAWCK
Sbjct: 422 DGKKIRSLEPNAWEKKIAQQSAKIEKMERDMHTKEDLKTVALGTSKINYLDPRITVAWCK 481
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
RHEVPIEKIF +SLL KF WAMDV+P++RF
Sbjct: 482 RHEVPIEKIFTKSLLEKFAWAMDVEPEYRF 511
[21][TOP]
>UniRef100_Q56XA9 DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis thaliana
RepID=Q56XA9_ARATH
Length = 396
Score = 147 bits (370), Expect = 5e-34
Identities = 70/90 (77%), Positives = 79/90 (87%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
DGKK ++L A EKKI+Q AKIEKM+RDM TKEDLKTVALGTS+INYLDPRITVAWCK
Sbjct: 304 DGKKIRSLEPNAWEKKIAQQSAKIEKMERDMHTKEDLKTVALGTSKINYLDPRITVAWCK 363
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
RHEVPIEKIF +SLL KF WAMDV+P++RF
Sbjct: 364 RHEVPIEKIFTKSLLEKFAWAMDVEPEYRF 393
[22][TOP]
>UniRef100_Q56X27 DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis thaliana
RepID=Q56X27_ARATH
Length = 270
Score = 147 bits (370), Expect = 5e-34
Identities = 70/90 (77%), Positives = 79/90 (87%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
DGKK ++L A EKKI+Q AKIEKM+RDM TKEDLKTVALGTS+INYLDPRITVAWCK
Sbjct: 178 DGKKIRSLEPNAWEKKIAQQSAKIEKMERDMHTKEDLKTVALGTSKINYLDPRITVAWCK 237
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
RHEVPIEKIF +SLL KF WAMDV+P++RF
Sbjct: 238 RHEVPIEKIFTKSLLEKFAWAMDVEPEYRF 267
[23][TOP]
>UniRef100_A9T3W2 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9T3W2_PHYPA
Length = 632
Score = 147 bits (370), Expect = 5e-34
Identities = 68/93 (73%), Positives = 82/93 (88%)
Frame = -1
Query: 480 KSPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVA 301
K +GK K+N + EALEKKI+ T KI+KM+ DM+ K+DLKTVALGTS+INY+DPRITVA
Sbjct: 540 KDSEGKVKRNQTPEALEKKIAATKQKIDKMRLDMRVKDDLKTVALGTSKINYMDPRITVA 599
Query: 300 WCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
WCKRHEVPIEKIFN+SLL+KF WAM+V+PDFRF
Sbjct: 600 WCKRHEVPIEKIFNKSLLSKFAWAMEVEPDFRF 632
[24][TOP]
>UniRef100_A9T368 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9T368_PHYPA
Length = 502
Score = 147 bits (370), Expect = 5e-34
Identities = 68/93 (73%), Positives = 82/93 (88%)
Frame = -1
Query: 480 KSPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVA 301
K +GK K+N + EALEKKI+ T KI+KM+ DM+ K+DLKTVALGTS+INY+DPRITVA
Sbjct: 410 KDSEGKVKRNQTPEALEKKIASTTQKIDKMRLDMRVKDDLKTVALGTSKINYMDPRITVA 469
Query: 300 WCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
WCKRHEVPIEKIFN+SLL+KF WAM+V+PDFRF
Sbjct: 470 WCKRHEVPIEKIFNKSLLSKFAWAMEVEPDFRF 502
[25][TOP]
>UniRef100_P30181 DNA topoisomerase 1 n=1 Tax=Arabidopsis thaliana RepID=TOP1_ARATH
Length = 916
Score = 147 bits (370), Expect = 5e-34
Identities = 70/90 (77%), Positives = 79/90 (87%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
DGKK ++L A EKKI+Q AKIEKM+RDM TKEDLKTVALGTS+INYLDPRITVAWCK
Sbjct: 824 DGKKIRSLEPNAWEKKIAQQSAKIEKMERDMHTKEDLKTVALGTSKINYLDPRITVAWCK 883
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
RHEVPIEKIF +SLL KF WAMDV+P++RF
Sbjct: 884 RHEVPIEKIFTKSLLEKFAWAMDVEPEYRF 913
[26][TOP]
>UniRef100_A5BM51 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5BM51_VITVI
Length = 1449
Score = 145 bits (366), Expect = 1e-33
Identities = 73/96 (76%), Positives = 84/96 (87%), Gaps = 3/96 (3%)
Frame = -1
Query: 480 KSPDGKKKKNLSSEA---LEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRI 310
K DGK++ NL+ EA LE+KI+QT+AKIEKM+RD TKEDLKTVALGTS+INYLDPRI
Sbjct: 1355 KDADGKRR-NLTPEATYRLERKIAQTNAKIEKMERDKDTKEDLKTVALGTSKINYLDPRI 1413
Query: 309 TVAWCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
+VAWCKR EVPIEK+FN+SLLAKF WAMDV PDFRF
Sbjct: 1414 SVAWCKRQEVPIEKVFNKSLLAKFAWAMDVPPDFRF 1449
[27][TOP]
>UniRef100_O24307 Topoisomerase I n=1 Tax=Pisum sativum RepID=O24307_PEA
Length = 892
Score = 133 bits (335), Expect(2) = 3e-32
Identities = 65/78 (83%), Positives = 72/78 (92%)
Frame = -1
Query: 480 KSPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVA 301
KS DGK K++L+ E LEKKISQT+AKIEKMQRDMKTK DLKTVALGTS+INYLDPRITVA
Sbjct: 795 KSSDGKSKRSLTPEVLEKKISQTNAKIEKMQRDMKTKVDLKTVALGTSKINYLDPRITVA 854
Query: 300 WCKRHEVPIEKIFNQSLL 247
WCKRHEVPIEK+F +SLL
Sbjct: 855 WCKRHEVPIEKLFTKSLL 872
Score = 28.5 bits (62), Expect(2) = 3e-32
Identities = 15/26 (57%), Positives = 17/26 (65%)
Frame = -2
Query: 272 KRFSTSLCWPSSLGLWMWTLTSDSEI 195
K F+ SL + LG WMWT SDSEI
Sbjct: 865 KLFTKSLL-QNLLGQWMWTQISDSEI 889
[28][TOP]
>UniRef100_P93119 DNA topoisomerase 1 n=1 Tax=Daucus carota RepID=TOP1_DAUCA
Length = 790
Score = 133 bits (335), Expect = 5e-30
Identities = 70/115 (60%), Positives = 83/115 (72%), Gaps = 22/115 (19%)
Frame = -1
Query: 480 KSPDGKKKKNLSSE----------------------ALEKKISQTHAKIEKMQRDMKTKE 367
K+ DGK K+NL+ + ++ KKI+QT+ KIEKM+RD +TKE
Sbjct: 676 KNSDGKPKRNLNLKRYKGKLLKLIQKLRKWSETRRLSVTKKIAQTNTKIEKMERDKETKE 735
Query: 366 DLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
DLKTVALGTS+INYLDPRITVAWCKRH+VPIEKIFN+SLLAKF WAMDV FRF
Sbjct: 736 DLKTVALGTSKINYLDPRITVAWCKRHDVPIEKIFNKSLLAKFAWAMDVVLIFRF 790
[29][TOP]
>UniRef100_B3H4K2 Uncharacterized protein At4g26701.1 n=1 Tax=Arabidopsis thaliana
RepID=B3H4K2_ARATH
Length = 69
Score = 124 bits (312), Expect = 2e-27
Identities = 57/68 (83%), Positives = 63/68 (92%)
Frame = -1
Query: 405 KIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIFNQSLLAKFTWAM 226
KIEKM+RDM+TKEDLKTVALGTS+INY+DPRITVAWCKRHE PIEKIFN+SLL KF WAM
Sbjct: 2 KIEKMERDMQTKEDLKTVALGTSKINYMDPRITVAWCKRHEAPIEKIFNKSLLEKFAWAM 61
Query: 225 DVDPDFRF 202
DV+P F F
Sbjct: 62 DVEPHFTF 69
[30][TOP]
>UniRef100_A8IDM1 DNA topoisomerase I (Fragment) n=1 Tax=Chlamydomonas reinhardtii
RepID=A8IDM1_CHLRE
Length = 586
Score = 120 bits (301), Expect = 5e-26
Identities = 57/79 (72%), Positives = 66/79 (83%)
Frame = -1
Query: 438 ALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIFN 259
AL KI + I K++ ++KEDLKTVALGTS+INY+DPRITVAWCKR+EVPIEKIFN
Sbjct: 508 ALNSKIDKKKQAIAKVELQARSKEDLKTVALGTSKINYMDPRITVAWCKRNEVPIEKIFN 567
Query: 258 QSLLAKFTWAMDVDPDFRF 202
+SLLAKF WAMDVDP FRF
Sbjct: 568 KSLLAKFNWAMDVDPTFRF 586
[31][TOP]
>UniRef100_B5Y3I3 Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B5Y3I3_PHATR
Length = 594
Score = 110 bits (274), Expect = 6e-23
Identities = 52/93 (55%), Positives = 69/93 (74%)
Frame = -1
Query: 480 KSPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVA 301
K P K + ++ E + KKI + KI KM+ D+K K+D K V+LGTS+INY+DPRI+VA
Sbjct: 494 KIPTKKSPQTMTDEQVVKKIEAWNGKISKMEMDLKHKDDNKEVSLGTSKINYMDPRISVA 553
Query: 300 WCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
WCKR+EVPIEKIF+++L KF WAM V PD+ F
Sbjct: 554 WCKRNEVPIEKIFSKTLRDKFNWAMAVVPDWEF 586
[32][TOP]
>UniRef100_Q7RE42 Eukaryotic DNA topoisomerase I, DNA binding, putative n=1
Tax=Plasmodium yoelii yoelii RepID=Q7RE42_PLAYO
Length = 886
Score = 105 bits (263), Expect = 1e-21
Identities = 49/88 (55%), Positives = 67/88 (76%)
Frame = -1
Query: 465 KKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRH 286
K K+N+ E+ +KK+ K+E ++ MK ++D KT+ALGTS+INY+DPRITVA+CK+
Sbjct: 799 KVKENMKEESCKKKLIALIKKVELLENQMKVRDDNKTIALGTSKINYMDPRITVAFCKQF 858
Query: 285 EVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
E+PIEKIFN+SL KF WAM V +FRF
Sbjct: 859 EIPIEKIFNRSLRLKFPWAMFVTKNFRF 886
[33][TOP]
>UniRef100_B3L6G4 Topoisomerase I, putative n=1 Tax=Plasmodium knowlesi strain H
RepID=B3L6G4_PLAKH
Length = 924
Score = 105 bits (263), Expect = 1e-21
Identities = 49/88 (55%), Positives = 67/88 (76%)
Frame = -1
Query: 465 KKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRH 286
K K+N+ E+ +KK+ K+E+++ MK ++D KT+ALGTS+INY+DPRITVA+CKR
Sbjct: 837 KVKENMKEESCKKKLIALIKKVEQLKHQMKVRDDNKTIALGTSKINYMDPRITVAFCKRF 896
Query: 285 EVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
E+PIEKIFN+SL KF WAM V +F F
Sbjct: 897 EIPIEKIFNRSLRLKFPWAMFVTKNFTF 924
[34][TOP]
>UniRef100_A5KB33 Topoisomerase I, putative n=1 Tax=Plasmodium vivax RepID=A5KB33_PLAVI
Length = 931
Score = 105 bits (263), Expect = 1e-21
Identities = 49/88 (55%), Positives = 67/88 (76%)
Frame = -1
Query: 465 KKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRH 286
K K+N+ E+ +KK+ K+E+++ MK ++D KT+ALGTS+INY+DPRITVA+CKR
Sbjct: 844 KVKENMKEESCKKKLIALIKKVEQLKHQMKVRDDNKTIALGTSKINYMDPRITVAFCKRF 903
Query: 285 EVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
E+PIEKIFN+SL KF WAM V +F F
Sbjct: 904 EIPIEKIFNRSLRLKFPWAMFVTKNFTF 931
[35][TOP]
>UniRef100_C1MGX0 DNA topoisomerase I n=1 Tax=Micromonas pusilla CCMP1545
RepID=C1MGX0_9CHLO
Length = 685
Score = 103 bits (256), Expect = 8e-21
Identities = 46/80 (57%), Positives = 62/80 (77%)
Frame = -1
Query: 441 EALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIF 262
E + KIS ++ K++ MK KEDLKTV+LGTS+INYLDPRIT+AWCKR+EVP +F
Sbjct: 606 EKNKSKISTMKERLAKLELQMKMKEDLKTVSLGTSKINYLDPRITIAWCKRNEVPPPTVF 665
Query: 261 NQSLLAKFTWAMDVDPDFRF 202
++L+ KF W+M+V+PDF F
Sbjct: 666 TRALVEKFNWSMEVEPDFDF 685
[36][TOP]
>UniRef100_Q9ZSC8 Topoisomerase I n=1 Tax=Nicotiana tabacum RepID=Q9ZSC8_TOBAC
Length = 852
Score = 102 bits (253), Expect = 2e-20
Identities = 46/68 (67%), Positives = 58/68 (85%)
Frame = -1
Query: 480 KSPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVA 301
K DGK K+NL+ EAL+KKI QT+ KIE +++ ++TKE+LKTVALGTS+INYLDPRITVA
Sbjct: 785 KGADGKAKRNLAPEALQKKIDQTNVKIENIEKQIETKEELKTVALGTSKINYLDPRITVA 844
Query: 300 WCKRHEVP 277
WC+RH P
Sbjct: 845 WCERHRFP 852
[37][TOP]
>UniRef100_Q00XV7 Putative DNA topoisomerase I (ISS) n=1 Tax=Ostreococcus tauri
RepID=Q00XV7_OSTTA
Length = 783
Score = 101 bits (252), Expect = 2e-20
Identities = 46/86 (53%), Positives = 63/86 (73%)
Frame = -1
Query: 459 KKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEV 280
KKN + +KK++ + K+ M+ KE+LKTV+LGTS+INYLDPRIT++WCKRHEV
Sbjct: 674 KKNKDDKNQKKKLTALKERAAKLAIQMEMKEELKTVSLGTSKINYLDPRITLSWCKRHEV 733
Query: 279 PIEKIFNQSLLAKFTWAMDVDPDFRF 202
P +F ++L+ KF WAMD D DF+F
Sbjct: 734 PPPTVFTKALIDKFHWAMDCDMDFKF 759
[38][TOP]
>UniRef100_B8CC91 Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335
RepID=B8CC91_THAPS
Length = 536
Score = 101 bits (252), Expect = 2e-20
Identities = 46/86 (53%), Positives = 68/86 (79%)
Frame = -1
Query: 459 KKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEV 280
+K + E + K+I+ KI+KM+ ++K K+D K V+LGTS++NY+DPRI+VAWCKR+EV
Sbjct: 443 EKKPTKEQVTKRITAWSEKIKKMELNIKHKDDNKEVSLGTSKLNYMDPRISVAWCKRNEV 502
Query: 279 PIEKIFNQSLLAKFTWAMDVDPDFRF 202
PIEKIF++++ KF WAM V PD++F
Sbjct: 503 PIEKIFSKTMRDKFNWAMAVTPDWQF 528
[39][TOP]
>UniRef100_Q8I3Z9 Topoisomerase I n=2 Tax=Plasmodium falciparum RepID=Q8I3Z9_PLAF7
Length = 839
Score = 101 bits (251), Expect = 3e-20
Identities = 46/88 (52%), Positives = 64/88 (72%)
Frame = -1
Query: 465 KKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRH 286
K K+N+ E+ +KK+ K+E + MK ++D KT+ALGTS+INY+DPRITVA+CK+
Sbjct: 752 KVKENMKEESCKKKLITLIKKVELLNNQMKVRDDNKTIALGTSKINYMDPRITVAFCKKF 811
Query: 285 EVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
E+PIEK+FN+SL KF WAM +F F
Sbjct: 812 EIPIEKVFNRSLRLKFPWAMFATKNFTF 839
[40][TOP]
>UniRef100_Q5CY81 Eukaryotic DNA topoisomerase I (Fragment) n=1 Tax=Cryptosporidium
parvum Iowa II RepID=Q5CY81_CRYPV
Length = 653
Score = 95.5 bits (236), Expect = 2e-18
Identities = 47/95 (49%), Positives = 67/95 (70%), Gaps = 5/95 (5%)
Frame = -1
Query: 471 DGKKKK-----NLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRIT 307
+GK++K N S + ++KKI +KI + +K K+D KTVAL TS+INY+DPRI+
Sbjct: 559 NGKQRKYPINLNSSLDVVQKKIDSIKSKISNLYLKIKIKDDNKTVALNTSKINYMDPRIS 618
Query: 306 VAWCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
VA+CK++++PI+KIFN+SL KF WAM DF F
Sbjct: 619 VAFCKKYDLPIDKIFNRSLRTKFPWAMYTRSDFSF 653
[41][TOP]
>UniRef100_Q5CN58 DNA topoisomerase I n=1 Tax=Cryptosporidium hominis
RepID=Q5CN58_CRYHO
Length = 641
Score = 95.5 bits (236), Expect = 2e-18
Identities = 47/95 (49%), Positives = 67/95 (70%), Gaps = 5/95 (5%)
Frame = -1
Query: 471 DGKKKK-----NLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRIT 307
+GK++K N S + ++KKI +KI + +K K+D KTVAL TS+INY+DPRI+
Sbjct: 547 NGKQRKYPINLNSSLDVVQKKIDSIKSKISNLYLKIKIKDDNKTVALNTSKINYMDPRIS 606
Query: 306 VAWCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
VA+CK++++PI+KIFN+SL KF WAM DF F
Sbjct: 607 VAFCKKYDLPIDKIFNRSLRTKFPWAMYTRSDFSF 641
[42][TOP]
>UniRef100_A4S5R8 Predicted protein n=1 Tax=Ostreococcus lucimarinus CCE9901
RepID=A4S5R8_OSTLU
Length = 491
Score = 94.7 bits (234), Expect = 3e-18
Identities = 43/86 (50%), Positives = 60/86 (69%)
Frame = -1
Query: 459 KKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEV 280
KK + +KK++ + K+ M KE+LKTV+LGTS+INYLDPRIT++WCKRHEV
Sbjct: 394 KKKTDDKNQKKKLAALKERQSKLAIQMNMKEELKTVSLGTSKINYLDPRITLSWCKRHEV 453
Query: 279 PIEKIFNQSLLAKFTWAMDVDPDFRF 202
P +F ++L+ KF WAMD + +F F
Sbjct: 454 PPNVVFTKALIDKFHWAMDCEMEFSF 479
[43][TOP]
>UniRef100_B6ABX7 DNA topoisomerase I, putative n=1 Tax=Cryptosporidium muris RN66
RepID=B6ABX7_9CRYT
Length = 660
Score = 94.4 bits (233), Expect = 4e-18
Identities = 46/95 (48%), Positives = 68/95 (71%), Gaps = 5/95 (5%)
Frame = -1
Query: 471 DGKKKK---NLSS--EALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRIT 307
+GK +K NLSS E ++KK+ K+ ++ +K K+D KTV+L TS++NY+DPRI+
Sbjct: 566 NGKPRKFPINLSSNSEIIQKKLDSIKTKLSNLELKIKIKDDNKTVSLNTSKLNYMDPRIS 625
Query: 306 VAWCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
VA+CK++E+PI+K+FN+SL KF WAM DF F
Sbjct: 626 VAFCKKYELPIDKVFNRSLRTKFPWAMYTRSDFSF 660
[44][TOP]
>UniRef100_A7AUT4 DNA topoisomerase n=1 Tax=Babesia bovis RepID=A7AUT4_BABBO
Length = 701
Score = 94.4 bits (233), Expect = 4e-18
Identities = 46/86 (53%), Positives = 61/86 (70%)
Frame = -1
Query: 459 KKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEV 280
++ + EA +KK+ + + M+ K+D KTVALGTS+INY+DPRITVA+CKR+EV
Sbjct: 616 RQGMKLEACQKKLETAMKRSKVHAIKMRIKDDNKTVALGTSKINYMDPRITVAFCKRYEV 675
Query: 279 PIEKIFNQSLLAKFTWAMDVDPDFRF 202
PIEKIFN+SL KF WAM D+ F
Sbjct: 676 PIEKIFNKSLRTKFPWAMYAGADYIF 701
[45][TOP]
>UniRef100_C1FD86 DNA topoisomerase I n=1 Tax=Micromonas sp. RCC299
RepID=C1FD86_9CHLO
Length = 635
Score = 92.8 bits (229), Expect = 1e-17
Identities = 38/75 (50%), Positives = 58/75 (77%)
Frame = -1
Query: 426 KISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIFNQSLL 247
KI ++ K++ MK K++LK+V+LGTS+INY+DPRIT+AWCK ++VP ++ ++L+
Sbjct: 561 KIRTLKERLSKLELQMKMKDELKSVSLGTSKINYMDPRITIAWCKHNDVPPPTVYTKALV 620
Query: 246 AKFTWAMDVDPDFRF 202
KF WAM+V+PDF F
Sbjct: 621 EKFNWAMEVEPDFDF 635
[46][TOP]
>UniRef100_Q4N5U3 DNA topoisomerase I, putative n=1 Tax=Theileria parva
RepID=Q4N5U3_THEPA
Length = 1003
Score = 92.8 bits (229), Expect = 1e-17
Identities = 49/94 (52%), Positives = 65/94 (69%), Gaps = 8/94 (8%)
Frame = -1
Query: 459 KKNLSSEALEKKISQTH----AKIEKMQRD----MKTKEDLKTVALGTSQINYLDPRITV 304
K + EA + K+S + A ++K Q+D M K+ KTVALGTS+INY+DPRITV
Sbjct: 910 KPGMKLEAAKNKLSTLNYLCFAPLKKKQKDHAIKMTIKDSNKTVALGTSKINYMDPRITV 969
Query: 303 AWCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
A+CK++E+PIEK+FN+SL KF WAM V DF F
Sbjct: 970 AFCKKYEIPIEKVFNKSLRMKFPWAMYVRSDFTF 1003
[47][TOP]
>UniRef100_UPI000056C59B UPI000056C59B related cluster n=1 Tax=Danio rerio
RepID=UPI000056C59B
Length = 196
Score = 92.0 bits (227), Expect = 2e-17
Identities = 46/97 (47%), Positives = 67/97 (69%), Gaps = 4/97 (4%)
Frame = -1
Query: 480 KSPDGKKKKNLSSEALEKK---ISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRI 310
K D + SS+ +EKK + + +++K+Q +E+ K +ALGTS++NYLDPRI
Sbjct: 100 KQVDKDTPSDKSSKLVEKKQKAVQRLCDQLKKLQLQETDREENKVIALGTSKLNYLDPRI 159
Query: 309 TVAWCKRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
TVAWCK+H+VPIEKIFN++ KF WA+D+ D F+F
Sbjct: 160 TVAWCKKHQVPIEKIFNKTHREKFAWAIDMTDESFQF 196
[48][TOP]
>UniRef100_Q6T721 Mitochondrial topoisomerase I n=1 Tax=Danio rerio
RepID=Q6T721_DANRE
Length = 600
Score = 92.0 bits (227), Expect = 2e-17
Identities = 46/97 (47%), Positives = 67/97 (69%), Gaps = 4/97 (4%)
Frame = -1
Query: 480 KSPDGKKKKNLSSEALEKK---ISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRI 310
K D + SS+ +EKK + + +++K+Q +E+ K +ALGTS++NYLDPRI
Sbjct: 504 KQVDKDTPSDKSSKLVEKKQKAVQRLCDQLKKLQLQETDREENKVIALGTSKLNYLDPRI 563
Query: 309 TVAWCKRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
TVAWCK+H+VPIEKIFN++ KF WA+D+ D F+F
Sbjct: 564 TVAWCKKHQVPIEKIFNKTHREKFAWAIDMTDESFQF 600
[49][TOP]
>UniRef100_Q4UDP8 DNA topoisomerase i, putative n=1 Tax=Theileria annulata
RepID=Q4UDP8_THEAN
Length = 999
Score = 91.7 bits (226), Expect = 2e-17
Identities = 45/86 (52%), Positives = 59/86 (68%)
Frame = -1
Query: 459 KKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEV 280
K + EA + K++ K + M K+ KTVALGTS+INY+DPRITVA+CK++E+
Sbjct: 914 KPGMKLEAAKNKLATLKKKQKDHNIKMTIKDSNKTVALGTSKINYMDPRITVAFCKKYEI 973
Query: 279 PIEKIFNQSLLAKFTWAMDVDPDFRF 202
PIEK+FN+SL KF WAM V DF F
Sbjct: 974 PIEKVFNKSLRMKFPWAMCVRSDFTF 999
[50][TOP]
>UniRef100_Q24BB2 Eukaryotic DNA topoisomerase I, catalytic core family protein n=1
Tax=Tetrahymena thermophila SB210 RepID=Q24BB2_TETTH
Length = 713
Score = 90.1 bits (222), Expect = 7e-17
Identities = 43/95 (45%), Positives = 64/95 (67%), Gaps = 5/95 (5%)
Frame = -1
Query: 471 DGKKKKNL-----SSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRIT 307
DGK K + + E +++ I + KI++ Q ++KE K +ALGTS+ NY DPRI+
Sbjct: 619 DGKHKMFVKKFPGTKEKIQEAIEKIKKKIDEEQNKKQSKEKNKEIALGTSKTNYNDPRIS 678
Query: 306 VAWCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
V WCK+ EVP+EK+F ++L+AKF WAMD D ++ F
Sbjct: 679 VVWCKKWEVPVEKVFPKTLIAKFVWAMDTDLEWSF 713
[51][TOP]
>UniRef100_A8N6Y9 Putative uncharacterized protein n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N6Y9_COPC7
Length = 863
Score = 90.1 bits (222), Expect = 7e-17
Identities = 43/86 (50%), Positives = 62/86 (72%)
Frame = -1
Query: 459 KKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEV 280
K+ +E LE+ I + +I+ + M +++ K VALGTS+INYLDPRITVAW ++V
Sbjct: 778 KRERPTEKLEEMIEKLDDRIKTFKLQMIDRDEGKEVALGTSKINYLDPRITVAWASANKV 837
Query: 279 PIEKIFNQSLLAKFTWAMDVDPDFRF 202
PIEK+F+++LL KF WAM VD D++F
Sbjct: 838 PIEKMFSKTLLEKFPWAMGVDDDWKF 863
[52][TOP]
>UniRef100_Q8IR39 Topoisomerase 1, isoform B n=1 Tax=Drosophila melanogaster
RepID=Q8IR39_DROME
Length = 581
Score = 89.0 bits (219), Expect = 2e-16
Identities = 45/103 (43%), Positives = 68/103 (66%), Gaps = 15/103 (14%)
Frame = -1
Query: 465 KKKKNLSSEALEKKISQTHAKIEKMQRDMKT--------------KEDLKTVALGTSQIN 328
K+K EA+EK S+ H++ EK + ++ +++ KT+ALGTS++N
Sbjct: 479 KEKIKAKREAIEKCESEYHSRDEKKGKQLERLRDQLKKLELQETDRDENKTIALGTSKLN 538
Query: 327 YLDPRITVAWCKRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
YLDPRI+VAWCK+H+VPIEKIFN++ KF WA+ + D ++RF
Sbjct: 539 YLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVHMADENYRF 581
[53][TOP]
>UniRef100_Q494M1 Topoisomerase 1, isoform C n=1 Tax=Drosophila melanogaster
RepID=Q494M1_DROME
Length = 974
Score = 89.0 bits (219), Expect = 2e-16
Identities = 45/103 (43%), Positives = 68/103 (66%), Gaps = 15/103 (14%)
Frame = -1
Query: 465 KKKKNLSSEALEKKISQTHAKIEKMQRDMKT--------------KEDLKTVALGTSQIN 328
K+K EA+EK S+ H++ EK + ++ +++ KT+ALGTS++N
Sbjct: 872 KEKIKAKREAIEKCESEYHSRDEKKGKQLERLRDQLKKLELQETDRDENKTIALGTSKLN 931
Query: 327 YLDPRITVAWCKRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
YLDPRI+VAWCK+H+VPIEKIFN++ KF WA+ + D ++RF
Sbjct: 932 YLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVHMADENYRF 974
[54][TOP]
>UniRef100_C6TPA7 AT12251p n=1 Tax=Drosophila melanogaster RepID=C6TPA7_DROME
Length = 581
Score = 89.0 bits (219), Expect = 2e-16
Identities = 45/103 (43%), Positives = 68/103 (66%), Gaps = 15/103 (14%)
Frame = -1
Query: 465 KKKKNLSSEALEKKISQTHAKIEKMQRDMKT--------------KEDLKTVALGTSQIN 328
K+K EA+EK S+ H++ EK + ++ +++ KT+ALGTS++N
Sbjct: 479 KEKIKAKREAIEKCESEYHSRDEKKGKQLERLRDQLKKLELQETDRDENKTIALGTSKLN 538
Query: 327 YLDPRITVAWCKRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
YLDPRI+VAWCK+H+VPIEKIFN++ KF WA+ + D ++RF
Sbjct: 539 YLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVHMADENYRF 581
[55][TOP]
>UniRef100_P30189 DNA topoisomerase 1 n=1 Tax=Drosophila melanogaster RepID=TOP1_DROME
Length = 972
Score = 89.0 bits (219), Expect = 2e-16
Identities = 45/103 (43%), Positives = 68/103 (66%), Gaps = 15/103 (14%)
Frame = -1
Query: 465 KKKKNLSSEALEKKISQTHAKIEKMQRDMKT--------------KEDLKTVALGTSQIN 328
K+K EA+EK S+ H++ EK + ++ +++ KT+ALGTS++N
Sbjct: 870 KEKIKAKREAIEKCESEYHSRDEKKGKQLERLRDQLKKLELQETDRDENKTIALGTSKLN 929
Query: 327 YLDPRITVAWCKRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
YLDPRI+VAWCK+H+VPIEKIFN++ KF WA+ + D ++RF
Sbjct: 930 YLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVHMADENYRF 972
[56][TOP]
>UniRef100_Q54RC3 DNA topoisomerase 1 n=1 Tax=Dictyostelium discoideum RepID=TOP1_DICDI
Length = 893
Score = 89.0 bits (219), Expect = 2e-16
Identities = 46/91 (50%), Positives = 65/91 (71%)
Frame = -1
Query: 474 PDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWC 295
PD K K +++KI++ +I+K + K++LKTVALGTS+INYLDPRITVAWC
Sbjct: 811 PDAKGK-------IKEKIAKYEEQIKKQEILKTGKDELKTVALGTSKINYLDPRITVAWC 863
Query: 294 KRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
K+++VP++KIF +SL KF W+ DV D+ F
Sbjct: 864 KKNKVPVDKIFTKSLRDKFPWS-DVGTDYIF 893
[57][TOP]
>UniRef100_B4L533 GI21653 n=1 Tax=Drosophila mojavensis RepID=B4L533_DROMO
Length = 1043
Score = 88.6 bits (218), Expect = 2e-16
Identities = 40/90 (44%), Positives = 66/90 (73%), Gaps = 1/90 (1%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ L+++ K++ + +++K++ +++ KT+ALGTS++NYLDPRITVAWCK+
Sbjct: 954 GSVKEKLNADKKGKQLERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRITVAWCKK 1013
Query: 288 HEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKIFN++ KF WA+ + D ++RF
Sbjct: 1014 YGVPIEKIFNKTHRTKFLWAIHMADENYRF 1043
[58][TOP]
>UniRef100_UPI00015B4D8F PREDICTED: similar to DNA topoisomerase type I n=1 Tax=Nasonia
vitripennis RepID=UPI00015B4D8F
Length = 1019
Score = 88.2 bits (217), Expect = 3e-16
Identities = 40/90 (44%), Positives = 64/90 (71%), Gaps = 1/90 (1%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ + E +K++ + ++ K++ +E+ K +ALGTS++NYLDPRI+VAWCK+
Sbjct: 930 GSVKEKVLYEKKKKQLDRLKEQLMKLEVQATDREENKEIALGTSKLNYLDPRISVAWCKK 989
Query: 288 HEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
H+VPIEKI+N++ KF WA+D+ PD+ F
Sbjct: 990 HDVPIEKIYNKTQRDKFRWAIDMAGPDYVF 1019
[59][TOP]
>UniRef100_UPI0001555600 PREDICTED: similar to mitochondrial topoisomerase I n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555600
Length = 689
Score = 88.2 bits (217), Expect = 3e-16
Identities = 46/95 (48%), Positives = 66/95 (69%), Gaps = 5/95 (5%)
Frame = -1
Query: 471 DGKKKKNLSSEA-LEKK---ISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITV 304
D K KK++ S++ LEKK + + ++ K+ KE+ K +ALGTS++NYLDPRI+V
Sbjct: 595 DHKAKKDIKSKSNLEKKKKLLQKIEEQLMKLSVQATDKEENKQIALGTSKLNYLDPRISV 654
Query: 303 AWCKRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
AWCK+ VPIEKI+N++ KF WA+D+ D DF F
Sbjct: 655 AWCKKFGVPIEKIYNKTQREKFAWAIDMADEDFEF 689
[60][TOP]
>UniRef100_UPI0000DB758E PREDICTED: similar to DNA topoisomerase I n=1 Tax=Apis mellifera
RepID=UPI0000DB758E
Length = 973
Score = 87.0 bits (214), Expect = 6e-16
Identities = 40/81 (49%), Positives = 58/81 (71%), Gaps = 1/81 (1%)
Frame = -1
Query: 441 EALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIF 262
E +K + + ++ K++ KE+ K +ALGTS++NYLDPRITVAWCK+H VPIEKI+
Sbjct: 893 EKKKKALDRLKEQLTKLEVQATDKEENKEIALGTSKLNYLDPRITVAWCKKHNVPIEKIY 952
Query: 261 NQSLLAKFTWAMDV-DPDFRF 202
N++ KF WA+D+ PD+ F
Sbjct: 953 NKTQRDKFRWAIDMAGPDYVF 973
[61][TOP]
>UniRef100_P07799 DNA topoisomerase 1 n=1 Tax=Schizosaccharomyces pombe
RepID=TOP1_SCHPO
Length = 814
Score = 86.7 bits (213), Expect = 8e-16
Identities = 38/82 (46%), Positives = 61/82 (74%)
Frame = -1
Query: 447 SSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEK 268
S E LEK++++ + +I M+ M K++ KT ALGTS+INY+DPR+T ++ KR +VPIEK
Sbjct: 733 SMEQLEKRLNKLNERINVMRTQMIDKDENKTTALGTSKINYIDPRLTYSFSKREDVPIEK 792
Query: 267 IFNQSLLAKFTWAMDVDPDFRF 202
+F++++ KF WA D PD+++
Sbjct: 793 LFSKTIRDKFNWAADTPPDWKW 814
[62][TOP]
>UniRef100_UPI000186E5D8 DNA topoisomerase, putative n=1 Tax=Pediculus humanus corporis
RepID=UPI000186E5D8
Length = 961
Score = 86.3 bits (212), Expect = 1e-15
Identities = 42/92 (45%), Positives = 66/92 (71%), Gaps = 2/92 (2%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKK-ISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWC 295
+ K+ + +EA +KK + + ++ K++ KE+ KT+ALGTS++NYLDPRI+VAWC
Sbjct: 870 NAKRNGDSGTEAKKKKQLDRLKEQLLKLEVQETDKEENKTIALGTSKLNYLDPRISVAWC 929
Query: 294 KRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
K++ VPIEKI+N++ KF WA+D+ PD+ F
Sbjct: 930 KKYNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 961
[63][TOP]
>UniRef100_UPI00017EFDA4 PREDICTED: similar to DNA topoisomerase I, partial n=1 Tax=Sus
scrofa RepID=UPI00017EFDA4
Length = 748
Score = 86.3 bits (212), Expect = 1e-15
Identities = 42/91 (46%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRITVAWCK
Sbjct: 660 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 717
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKI+N++ KF WA+D+ D D+ F
Sbjct: 718 KWGVPIEKIYNKTQREKFAWAIDMADEDYEF 748
[64][TOP]
>UniRef100_UPI0001797824 PREDICTED: similar to topoisomerase I, partial n=1 Tax=Equus
caballus RepID=UPI0001797824
Length = 765
Score = 86.3 bits (212), Expect = 1e-15
Identities = 42/91 (46%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRITVAWCK
Sbjct: 677 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 734
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKI+N++ KF WA+D+ D D+ F
Sbjct: 735 KWGVPIEKIYNKTQREKFAWAIDMADEDYEF 765
[65][TOP]
>UniRef100_UPI00006D45A8 PREDICTED: similar to DNA topoisomerase I n=1 Tax=Macaca mulatta
RepID=UPI00006D45A8
Length = 767
Score = 86.3 bits (212), Expect = 1e-15
Identities = 42/91 (46%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRITVAWCK
Sbjct: 679 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 736
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKI+N++ KF WA+D+ D D+ F
Sbjct: 737 KWGVPIEKIYNKTQREKFAWAIDMADEDYEF 767
[66][TOP]
>UniRef100_UPI00005A45B7 PREDICTED: similar to DNA topoisomerase I n=1 Tax=Canis lupus
familiaris RepID=UPI00005A45B7
Length = 1004
Score = 86.3 bits (212), Expect = 1e-15
Identities = 42/91 (46%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRITVAWCK
Sbjct: 916 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 973
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKI+N++ KF WA+D+ D D+ F
Sbjct: 974 KWGVPIEKIYNKTQREKFAWAIDMADEDYEF 1004
[67][TOP]
>UniRef100_UPI0001B7BF13 similar to topoisomerase (DNA) I (LOC499179), mRNA n=1 Tax=Rattus
norvegicus RepID=UPI0001B7BF13
Length = 760
Score = 86.3 bits (212), Expect = 1e-15
Identities = 43/91 (47%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK +S + +++ + K+E D +E+ K +ALGTS++NYLDPRITVAWCK
Sbjct: 673 DAKTKKVVSKKKAVQRLEEQLMKLEVQATD---REENKQIALGTSKLNYLDPRITVAWCK 729
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKI+N++ KF WA+D+ D D+ F
Sbjct: 730 KWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 760
[68][TOP]
>UniRef100_UPI00015DF5D0 topoisomerase (DNA) I n=1 Tax=Mus musculus RepID=UPI00015DF5D0
Length = 758
Score = 86.3 bits (212), Expect = 1e-15
Identities = 42/91 (46%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRITVAWCK
Sbjct: 670 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 727
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKI+N++ KF WA+D+ D D+ F
Sbjct: 728 KWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 758
[69][TOP]
>UniRef100_UPI0000EB0F30 Topoisomerase I n=1 Tax=Canis lupus familiaris RepID=UPI0000EB0F30
Length = 752
Score = 86.3 bits (212), Expect = 1e-15
Identities = 42/91 (46%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRITVAWCK
Sbjct: 664 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 721
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKI+N++ KF WA+D+ D D+ F
Sbjct: 722 KWGVPIEKIYNKTQREKFAWAIDMADEDYEF 752
[70][TOP]
>UniRef100_UPI00006154BF PREDICTED: topoisomerase (DNA) I n=1 Tax=Bos taurus
RepID=UPI00006154BF
Length = 769
Score = 86.3 bits (212), Expect = 1e-15
Identities = 42/91 (46%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRITVAWCK
Sbjct: 681 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 738
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKI+N++ KF WA+D+ D D+ F
Sbjct: 739 KWGVPIEKIYNKTQREKFAWAIDMADEDYEF 769
[71][TOP]
>UniRef100_Q6LBJ1 Topoisomerase I (Fragment) n=1 Tax=Mus musculus RepID=Q6LBJ1_MOUSE
Length = 115
Score = 86.3 bits (212), Expect = 1e-15
Identities = 42/91 (46%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRITVAWCK
Sbjct: 27 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 84
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKI+N++ KF WA+D+ D D+ F
Sbjct: 85 KWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 115
[72][TOP]
>UniRef100_Q3TSR2 Putative uncharacterized protein (Fragment) n=1 Tax=Mus musculus
RepID=Q3TSR2_MOUSE
Length = 144
Score = 86.3 bits (212), Expect = 1e-15
Identities = 42/91 (46%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRITVAWCK
Sbjct: 56 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 113
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKI+N++ KF WA+D+ D D+ F
Sbjct: 114 KWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 144
[73][TOP]
>UniRef100_Q5IFJ5 TOP1 (Fragment) n=1 Tax=Macaca fascicularis RepID=Q5IFJ5_MACFA
Length = 560
Score = 86.3 bits (212), Expect = 1e-15
Identities = 42/91 (46%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRITVAWCK
Sbjct: 472 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 529
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKI+N++ KF WA+D+ D D+ F
Sbjct: 530 KWGVPIEKIYNKTQREKFAWAIDMADEDYEF 560
[74][TOP]
>UniRef100_B9Q6S5 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii VEG
RepID=B9Q6S5_TOXGO
Length = 953
Score = 86.3 bits (212), Expect = 1e-15
Identities = 40/60 (66%), Positives = 49/60 (81%)
Frame = -1
Query: 381 MKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
+K K+D KTVALGTS+INY+DPRITVA+CK++EVPIEK+FN+SL KF WAM F F
Sbjct: 894 IKLKDDNKTVALGTSKINYMDPRITVAFCKKYEVPIEKLFNKSLRLKFPWAMFAKSTFEF 953
[75][TOP]
>UniRef100_B9PWF4 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii GT1
RepID=B9PWF4_TOXGO
Length = 953
Score = 86.3 bits (212), Expect = 1e-15
Identities = 40/60 (66%), Positives = 49/60 (81%)
Frame = -1
Query: 381 MKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
+K K+D KTVALGTS+INY+DPRITVA+CK++EVPIEK+FN+SL KF WAM F F
Sbjct: 894 IKLKDDNKTVALGTSKINYMDPRITVAFCKKYEVPIEKLFNKSLRLKFPWAMFAKSTFEF 953
[76][TOP]
>UniRef100_B6KM03 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii ME49
RepID=B6KM03_TOXGO
Length = 953
Score = 86.3 bits (212), Expect = 1e-15
Identities = 40/60 (66%), Positives = 49/60 (81%)
Frame = -1
Query: 381 MKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
+K K+D KTVALGTS+INY+DPRITVA+CK++EVPIEK+FN+SL KF WAM F F
Sbjct: 894 IKLKDDNKTVALGTSKINYMDPRITVAFCKKYEVPIEKLFNKSLRLKFPWAMFAKSTFEF 953
[77][TOP]
>UniRef100_B3NTM5 GG17874 n=1 Tax=Drosophila erecta RepID=B3NTM5_DROER
Length = 969
Score = 86.3 bits (212), Expect = 1e-15
Identities = 37/77 (48%), Positives = 60/77 (77%), Gaps = 1/77 (1%)
Frame = -1
Query: 429 KKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIFNQSL 250
K++ + +++K++ +++ KT+ALGTS++NYLDPRI+VAWCK+H+VPIEKIFN++
Sbjct: 893 KQLERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQ 952
Query: 249 LAKFTWAMDV-DPDFRF 202
KF WA+ + D ++RF
Sbjct: 953 RTKFLWAVHMADENYRF 969
[78][TOP]
>UniRef100_Q9BVT2 Putative uncharacterized protein (Fragment) n=1 Tax=Homo sapiens
RepID=Q9BVT2_HUMAN
Length = 176
Score = 86.3 bits (212), Expect = 1e-15
Identities = 42/91 (46%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRITVAWCK
Sbjct: 88 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 145
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKI+N++ KF WA+D+ D D+ F
Sbjct: 146 KWGVPIEKIYNKTQREKFAWAIDMADEDYEF 176
[79][TOP]
>UniRef100_B9EG90 Topoisomerase (DNA) I n=1 Tax=Homo sapiens RepID=B9EG90_HUMAN
Length = 765
Score = 86.3 bits (212), Expect = 1e-15
Identities = 42/91 (46%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRITVAWCK
Sbjct: 677 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 734
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKI+N++ KF WA+D+ D D+ F
Sbjct: 735 KWGVPIEKIYNKTQREKFAWAIDMADEDYEF 765
[80][TOP]
>UniRef100_Q9WUL0 DNA topoisomerase 1 n=1 Tax=Rattus norvegicus RepID=TOP1_RAT
Length = 767
Score = 86.3 bits (212), Expect = 1e-15
Identities = 42/91 (46%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRITVAWCK
Sbjct: 679 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 736
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKI+N++ KF WA+D+ D D+ F
Sbjct: 737 KWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767
[81][TOP]
>UniRef100_Q04750 DNA topoisomerase 1 n=1 Tax=Mus musculus RepID=TOP1_MOUSE
Length = 767
Score = 86.3 bits (212), Expect = 1e-15
Identities = 42/91 (46%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRITVAWCK
Sbjct: 679 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 736
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKI+N++ KF WA+D+ D D+ F
Sbjct: 737 KWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767
[82][TOP]
>UniRef100_P11387 DNA topoisomerase 1 n=1 Tax=Homo sapiens RepID=TOP1_HUMAN
Length = 765
Score = 86.3 bits (212), Expect = 1e-15
Identities = 42/91 (46%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRITVAWCK
Sbjct: 677 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 734
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKI+N++ KF WA+D+ D D+ F
Sbjct: 735 KWGVPIEKIYNKTQREKFAWAIDMADEDYEF 765
[83][TOP]
>UniRef100_Q07050 DNA topoisomerase 1 n=1 Tax=Cricetulus griseus RepID=TOP1_CRIGR
Length = 767
Score = 86.3 bits (212), Expect = 1e-15
Identities = 42/91 (46%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRITVAWCK
Sbjct: 679 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 736
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKI+N++ KF WA+D+ D D+ F
Sbjct: 737 KWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767
[84][TOP]
>UniRef100_Q7YR26 DNA topoisomerase 1 n=1 Tax=Chlorocebus aethiops RepID=TOP1_CERAE
Length = 767
Score = 86.3 bits (212), Expect = 1e-15
Identities = 42/91 (46%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRITVAWCK
Sbjct: 679 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 736
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKI+N++ KF WA+D+ D D+ F
Sbjct: 737 KWGVPIEKIYNKTQREKFAWAIDMADEDYEF 767
[85][TOP]
>UniRef100_B5DMS2 GA24044 n=1 Tax=Drosophila pseudoobscura pseudoobscura
RepID=B5DMS2_DROPS
Length = 1054
Score = 85.9 bits (211), Expect = 1e-15
Identities = 38/90 (42%), Positives = 66/90 (73%), Gaps = 1/90 (1%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ ++++ K++ + +++K++ +++ KT+ALGTS++NYLDPRI+VAWCK+
Sbjct: 965 GSVKEKVNADKKGKQLERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKK 1024
Query: 288 HEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKIFN++ KF WA+ + D ++RF
Sbjct: 1025 NGVPIEKIFNKTQRTKFLWAVHMADENYRF 1054
[86][TOP]
>UniRef100_B4GVZ4 GL14571 n=1 Tax=Drosophila persimilis RepID=B4GVZ4_DROPE
Length = 1042
Score = 85.9 bits (211), Expect = 1e-15
Identities = 38/90 (42%), Positives = 66/90 (73%), Gaps = 1/90 (1%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ ++++ K++ + +++K++ +++ KT+ALGTS++NYLDPRI+VAWCK+
Sbjct: 953 GSVKEKVNADKKGKQLERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKK 1012
Query: 288 HEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKIFN++ KF WA+ + D ++RF
Sbjct: 1013 NGVPIEKIFNKTQRTKFLWAVHMADENYRF 1042
[87][TOP]
>UniRef100_UPI00017B1DB6 UPI00017B1DB6 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B1DB6
Length = 770
Score = 85.5 bits (210), Expect = 2e-15
Identities = 42/93 (45%), Positives = 62/93 (66%), Gaps = 1/93 (1%)
Frame = -1
Query: 477 SPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAW 298
S D K KK + E K + + ++ K+Q +E+ K +ALGTS++NYLDPRI+VAW
Sbjct: 680 SHDDKSKKAV--EVKRKAVQRIEEQLMKLQVQATDREENKQIALGTSKLNYLDPRISVAW 737
Query: 297 CKRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
CK+ +PIEKI+N++ KF WA+D+ + DF F
Sbjct: 738 CKKFGIPIEKIYNKTQREKFAWAIDMAEKDFEF 770
[88][TOP]
>UniRef100_UPI00016E5FAF UPI00016E5FAF related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5FAF
Length = 573
Score = 85.5 bits (210), Expect = 2e-15
Identities = 42/93 (45%), Positives = 62/93 (66%), Gaps = 1/93 (1%)
Frame = -1
Query: 477 SPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAW 298
S D K KK + E K + + ++ K+Q +E+ K +ALGTS++NYLDPRI+VAW
Sbjct: 483 SHDDKSKKAV--EVKRKAVQRIEEQLMKLQVQATDREENKQIALGTSKLNYLDPRISVAW 540
Query: 297 CKRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
CK+ +PIEKI+N++ KF WA+D+ + DF F
Sbjct: 541 CKKFGIPIEKIYNKTQREKFAWAIDMAEKDFEF 573
[89][TOP]
>UniRef100_UPI00016E5F98 UPI00016E5F98 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F98
Length = 790
Score = 85.5 bits (210), Expect = 2e-15
Identities = 42/93 (45%), Positives = 62/93 (66%), Gaps = 1/93 (1%)
Frame = -1
Query: 477 SPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAW 298
S D K KK + E K + + ++ K+Q +E+ K +ALGTS++NYLDPRI+VAW
Sbjct: 700 SHDDKSKKAV--EVKRKAVQRIEEQLMKLQVQATDREENKQIALGTSKLNYLDPRISVAW 757
Query: 297 CKRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
CK+ +PIEKI+N++ KF WA+D+ + DF F
Sbjct: 758 CKKFGIPIEKIYNKTQREKFAWAIDMAEKDFEF 790
[90][TOP]
>UniRef100_UPI00016E5F96 UPI00016E5F96 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F96
Length = 767
Score = 85.5 bits (210), Expect = 2e-15
Identities = 42/93 (45%), Positives = 62/93 (66%), Gaps = 1/93 (1%)
Frame = -1
Query: 477 SPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAW 298
S D K KK + E K + + ++ K+Q +E+ K +ALGTS++NYLDPRI+VAW
Sbjct: 677 SHDDKSKKAV--EVKRKAVQRIEEQLMKLQVQATDREENKQIALGTSKLNYLDPRISVAW 734
Query: 297 CKRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
CK+ +PIEKI+N++ KF WA+D+ + DF F
Sbjct: 735 CKKFGIPIEKIYNKTQREKFAWAIDMAEKDFEF 767
[91][TOP]
>UniRef100_Q90WS0 Topoisomerase I alpha n=1 Tax=Takifugu rubripes RepID=Q90WS0_TAKRU
Length = 767
Score = 85.5 bits (210), Expect = 2e-15
Identities = 42/93 (45%), Positives = 62/93 (66%), Gaps = 1/93 (1%)
Frame = -1
Query: 477 SPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAW 298
S D K KK + E K + + ++ K+Q +E+ K +ALGTS++NYLDPRI+VAW
Sbjct: 677 SHDDKSKKAV--EVKRKAVQRIEEQLMKLQVQATDREENKQIALGTSKLNYLDPRISVAW 734
Query: 297 CKRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
CK+ +PIEKI+N++ KF WA+D+ + DF F
Sbjct: 735 CKKFGIPIEKIYNKTQREKFAWAIDMAEKDFEF 767
[92][TOP]
>UniRef100_Q6T722 Mitochondrial topoisomerase I n=1 Tax=Gallus gallus
RepID=Q6T722_CHICK
Length = 593
Score = 85.5 bits (210), Expect = 2e-15
Identities = 43/93 (46%), Positives = 62/93 (66%), Gaps = 5/93 (5%)
Frame = -1
Query: 465 KKKKNLSSEA----LEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAW 298
K KK+ +EA +K + + ++ K+ KE+ K +ALGTS++NYLDPRI++AW
Sbjct: 501 KDKKDAKAEANVQKKKKLLERLKEQLAKLNVQATDKEENKQIALGTSKLNYLDPRISIAW 560
Query: 297 CKRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
CK+ VPIEKIFN++ KF WA+D+ D DF F
Sbjct: 561 CKKFGVPIEKIFNKTQREKFAWAIDMTDEDFEF 593
[93][TOP]
>UniRef100_Q4T6N6 Chromosome 9 SCAF8684, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4T6N6_TETNG
Length = 783
Score = 85.5 bits (210), Expect = 2e-15
Identities = 42/93 (45%), Positives = 62/93 (66%), Gaps = 1/93 (1%)
Frame = -1
Query: 477 SPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAW 298
S D K KK + E K + + ++ K+Q +E+ K +ALGTS++NYLDPRI+VAW
Sbjct: 693 SHDDKSKKAV--EVKRKAVQRIEEQLMKLQVQATDREENKQIALGTSKLNYLDPRISVAW 750
Query: 297 CKRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
CK+ +PIEKI+N++ KF WA+D+ + DF F
Sbjct: 751 CKKFGIPIEKIYNKTQREKFAWAIDMAEKDFEF 783
[94][TOP]
>UniRef100_B4ILF9 GM19769 n=1 Tax=Drosophila sechellia RepID=B4ILF9_DROSE
Length = 970
Score = 85.1 bits (209), Expect = 2e-15
Identities = 38/85 (44%), Positives = 62/85 (72%), Gaps = 1/85 (1%)
Frame = -1
Query: 453 NLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPI 274
N E K++ + +++K++ +++ KT+ALGTS++NYLDPRI+VAWCK+++VPI
Sbjct: 886 NSRDEKKGKQLDRLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKNDVPI 945
Query: 273 EKIFNQSLLAKFTWAMDV-DPDFRF 202
EKIFN++ KF WA+ + D ++RF
Sbjct: 946 EKIFNKTQRTKFLWAVHMADENYRF 970
[95][TOP]
>UniRef100_B3MR83 GF21232 n=1 Tax=Drosophila ananassae RepID=B3MR83_DROAN
Length = 990
Score = 85.1 bits (209), Expect = 2e-15
Identities = 37/77 (48%), Positives = 59/77 (76%), Gaps = 1/77 (1%)
Frame = -1
Query: 429 KKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIFNQSL 250
K++ + +++K++ +++ KT+ALGTS++NYLDPRI+VAWCK+H VPIEKIFN++
Sbjct: 914 KQLERLKEQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHGVPIEKIFNKTQ 973
Query: 249 LAKFTWAMDV-DPDFRF 202
KF WA+ + D ++RF
Sbjct: 974 RTKFLWAVHMADENYRF 990
[96][TOP]
>UniRef100_B0WA62 Putative uncharacterized protein n=1 Tax=Culex quinquefasciatus
RepID=B0WA62_CULQU
Length = 962
Score = 85.1 bits (209), Expect = 2e-15
Identities = 36/83 (43%), Positives = 61/83 (73%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K ++ + +K++ + +++K++ +++ KT+ALGTS++NYLDPRI+VAWCK+
Sbjct: 873 GSVKGSVDRDKKQKQLERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKK 932
Query: 288 HEVPIEKIFNQSLLAKFTWAMDV 220
+VPIEKIFN++ KF WA+D+
Sbjct: 933 FDVPIEKIFNKTQRDKFRWAIDM 955
[97][TOP]
>UniRef100_B4M707 GJ16891 n=1 Tax=Drosophila virilis RepID=B4M707_DROVI
Length = 1045
Score = 84.7 bits (208), Expect = 3e-15
Identities = 39/90 (43%), Positives = 64/90 (71%), Gaps = 1/90 (1%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ + ++ K + + +++K++ +++ KT+ALGTS++NYLDPRITVAWCK+
Sbjct: 956 GSVKERVIADKKGKILERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRITVAWCKK 1015
Query: 288 HEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKIFN++ KF WA+ + D ++RF
Sbjct: 1016 YGVPIEKIFNKTHRTKFLWAIHMADENYRF 1045
[98][TOP]
>UniRef100_A7SLG4 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7SLG4_NEMVE
Length = 502
Score = 84.7 bits (208), Expect = 3e-15
Identities = 42/95 (44%), Positives = 62/95 (65%), Gaps = 8/95 (8%)
Frame = -1
Query: 462 KKKNLSSEALEKKISQTHAKIEKMQRDM-------KTKEDLKTVALGTSQINYLDPRITV 304
K K SE+ K + + A++++++ + KE+ K +ALGTS++NYLDPRITV
Sbjct: 408 KAKESKSESNNKAVEKKKAQVQRLEEQLFKLEVTATDKEENKEIALGTSKLNYLDPRITV 467
Query: 303 AWCKRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
AWCK+ EVPIEK +N++ KF WA+D+ DF F
Sbjct: 468 AWCKKFEVPIEKAYNKTQREKFAWAIDMAGEDFVF 502
[99][TOP]
>UniRef100_UPI000194BDF0 PREDICTED: topoisomerase (DNA) I, mitochondrial n=1 Tax=Taeniopygia
guttata RepID=UPI000194BDF0
Length = 662
Score = 84.3 bits (207), Expect = 4e-15
Identities = 40/87 (45%), Positives = 58/87 (66%), Gaps = 1/87 (1%)
Frame = -1
Query: 459 KKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEV 280
K L+ E +K + + ++ KM KE+ K +ALGTS++NYLDPRITVAWCK+ +
Sbjct: 576 KAELNVEKKKKLLKRLEEQLAKMNIQATDKEENKQIALGTSKLNYLDPRITVAWCKKFGI 635
Query: 279 PIEKIFNQSLLAKFTWAMDV-DPDFRF 202
PIE+I+N++ KF WA+D+ DF F
Sbjct: 636 PIERIYNKTQREKFAWAIDMAGEDFEF 662
[100][TOP]
>UniRef100_C7E3P0 Topoisomerase family protein (Fragment) n=1 Tax=Caenorhabditis
brenneri RepID=C7E3P0_CAEBE
Length = 159
Score = 84.3 bits (207), Expect = 4e-15
Identities = 36/82 (43%), Positives = 56/82 (68%)
Frame = -1
Query: 465 KKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRH 286
K + E +KK + +++K++ K++ K +ALGTS++NYLDPRITVAWCK H
Sbjct: 68 KHARGADKEKAQKKYDRLKEQLKKLKIARTDKDENKQIALGTSKLNYLDPRITVAWCKEH 127
Query: 285 EVPIEKIFNQSLLAKFTWAMDV 220
+VP+EK+F ++ KF WA+D+
Sbjct: 128 DVPLEKVFTKTHREKFRWAIDM 149
[101][TOP]
>UniRef100_UPI0001792028 PREDICTED: similar to AGAP004078-PA n=1 Tax=Acyrthosiphon pisum
RepID=UPI0001792028
Length = 1011
Score = 84.0 bits (206), Expect = 5e-15
Identities = 38/84 (45%), Positives = 56/84 (66%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
DG E +K + + ++ K++ KE+ KT+ALGTS++NYLDPRI+VAWCK
Sbjct: 657 DGSVHSKTQLEKRKKALERLKEQLTKLEVQETDKEENKTIALGTSKLNYLDPRISVAWCK 716
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV 220
+ VPIEKI+N++ KF WA+D+
Sbjct: 717 KFNVPIEKIYNKTQRDKFRWAIDM 740
[102][TOP]
>UniRef100_UPI000155C8C4 PREDICTED: similar to topoisomerase I n=1 Tax=Ornithorhynchus
anatinus RepID=UPI000155C8C4
Length = 781
Score = 84.0 bits (206), Expect = 5e-15
Identities = 40/91 (43%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + E +K + + ++ K++ +E+ K +ALGTS++NYLDPRI+VAWCK
Sbjct: 693 DAKSKKVV--ETKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCK 750
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ +PIEKI+N++ KF WA+D+ D D+ F
Sbjct: 751 KWGIPIEKIYNKTQREKFAWAIDMADEDYEF 781
[103][TOP]
>UniRef100_B4NCJ2 GK25865 n=1 Tax=Drosophila willistoni RepID=B4NCJ2_DROWI
Length = 997
Score = 84.0 bits (206), Expect = 5e-15
Identities = 37/90 (41%), Positives = 65/90 (72%), Gaps = 1/90 (1%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ ++++ K++ + +++K++ +++ KT+AL TS++NYLDPRI+VAWCK+
Sbjct: 908 GSVKEKVNADKKGKQLERLKEQLKKLELQETDRDENKTIALSTSKLNYLDPRISVAWCKK 967
Query: 288 HEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKIFN++ KF WA+ + D ++RF
Sbjct: 968 NGVPIEKIFNKTQRTKFLWAIHMADENYRF 997
[104][TOP]
>UniRef100_B4JLU3 GH24453 n=1 Tax=Drosophila grimshawi RepID=B4JLU3_DROGR
Length = 1063
Score = 84.0 bits (206), Expect = 5e-15
Identities = 37/90 (41%), Positives = 65/90 (72%), Gaps = 1/90 (1%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ ++++ K++ + +++K++ +++ KT+AL TS++NYLDPRI+VAWCK+
Sbjct: 974 GSVKEKVNADKKAKQLERLKDQLKKLELQETDRDENKTIALSTSKLNYLDPRISVAWCKK 1033
Query: 288 HEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKIFN++ KF WA+ + D ++RF
Sbjct: 1034 NGVPIEKIFNKTQRTKFLWAIHMADENYRF 1063
[105][TOP]
>UniRef100_A8XXL4 C. briggsae CBR-TOP-1 protein n=1 Tax=Caenorhabditis briggsae AF16
RepID=A8XXL4_CAEBR
Length = 840
Score = 84.0 bits (206), Expect = 5e-15
Identities = 38/92 (41%), Positives = 60/92 (65%), Gaps = 4/92 (4%)
Frame = -1
Query: 465 KKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRH 286
K + E +KK Q +++K++ K++ K +ALGTS++NY+DPRITVAWCK+
Sbjct: 749 KSARGAEKEKAQKKYDQKKEQLKKLKIQRTDKDENKQIALGTSKLNYIDPRITVAWCKKF 808
Query: 285 EVPIEKIFNQSLLAKFTWAMDV----DPDFRF 202
EVP+E++F ++ KF WA+D+ D +F F
Sbjct: 809 EVPLERVFTKTHREKFRWAIDMTMTTDEEFVF 840
[106][TOP]
>UniRef100_UPI000194D872 PREDICTED: topoisomerase (DNA) I n=1 Tax=Taeniopygia guttata
RepID=UPI000194D872
Length = 775
Score = 83.6 bits (205), Expect = 6e-15
Identities = 39/91 (42%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRI+VAWCK
Sbjct: 687 DEKSKKTVESK--KKAVQRIEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCK 744
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ +PIEKI+N++ KF WA+D+ + D+ F
Sbjct: 745 KWGIPIEKIYNKTQREKFAWAIDMAEEDYEF 775
[107][TOP]
>UniRef100_UPI0000ECD01B topoisomerase (DNA) I, mitochondrial n=1 Tax=Gallus gallus
RepID=UPI0000ECD01B
Length = 593
Score = 83.6 bits (205), Expect = 6e-15
Identities = 41/91 (45%), Positives = 60/91 (65%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K N+ + +K + + ++ K+ KE+ K +ALGTS++NYLDPRI++AWCK
Sbjct: 505 DAKAAGNVQKK--KKLLERLKEQLAKLNVQATDKEENKQIALGTSKLNYLDPRISIAWCK 562
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKIFN++ KF WA+D+ D DF F
Sbjct: 563 KFGVPIEKIFNKTQREKFAWAIDMTDEDFEF 593
[108][TOP]
>UniRef100_B4PWL3 GE17178 n=1 Tax=Drosophila yakuba RepID=B4PWL3_DROYA
Length = 580
Score = 83.6 bits (205), Expect = 6e-15
Identities = 36/77 (46%), Positives = 60/77 (77%), Gaps = 1/77 (1%)
Frame = -1
Query: 429 KKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIFNQSL 250
K++ + +++K++ +++ KT+ALGTS++NYLDPRI+VAWCK+++VPIEKIFN++
Sbjct: 504 KQLERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKNDVPIEKIFNKTQ 563
Query: 249 LAKFTWAMDV-DPDFRF 202
KF WA+ + D ++RF
Sbjct: 564 RTKFLWAVHMADENYRF 580
[109][TOP]
>UniRef100_A0DKX8 Chromosome undetermined scaffold_55, whole genome shotgun sequence
n=1 Tax=Paramecium tetraurelia RepID=A0DKX8_PARTE
Length = 596
Score = 83.6 bits (205), Expect = 6e-15
Identities = 40/98 (40%), Positives = 65/98 (66%), Gaps = 8/98 (8%)
Frame = -1
Query: 471 DGKKKKNL--------SSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDP 316
+G +KKN + +++ I +T K +K + ++ KE+ K +ALGTS+ NY DP
Sbjct: 499 EGSQKKNSIFIKKFPGQHDKIKQTIQKTQEKYQKELKGLEKKEENKEIALGTSKTNYNDP 558
Query: 315 RITVAWCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
RI+VA+CK H+VPIE++F+++L KF WAM D +++F
Sbjct: 559 RISVAFCKVHDVPIERVFSKTLRNKFIWAMATDSNWKF 596
[110][TOP]
>UniRef100_Q17HT9 DNA topoisomerase type I n=1 Tax=Aedes aegypti RepID=Q17HT9_AEDAE
Length = 966
Score = 83.2 bits (204), Expect = 8e-15
Identities = 35/80 (43%), Positives = 58/80 (72%)
Frame = -1
Query: 459 KKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEV 280
+ ++ + +K++ + ++ K++ K++ KT+ALGTS++NYLDPRI+VAWCK+ V
Sbjct: 880 RDKVAKDKKQKQLERLREQLNKLELQETDKDENKTIALGTSKLNYLDPRISVAWCKKFGV 939
Query: 279 PIEKIFNQSLLAKFTWAMDV 220
PIEKIFN++ KF WA+D+
Sbjct: 940 PIEKIFNKTQRDKFRWAIDM 959
[111][TOP]
>UniRef100_O17966-2 Isoform b of DNA topoisomerase 1 n=1 Tax=Caenorhabditis elegans
RepID=O17966-2
Length = 734
Score = 83.2 bits (204), Expect = 8e-15
Identities = 35/82 (42%), Positives = 56/82 (68%)
Frame = -1
Query: 465 KKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRH 286
K + E +KK + +++K++ K++ K +ALGTS++NY+DPRITVAWCK+
Sbjct: 643 KSARGAEKEKAQKKYDRLKEQLKKLKISRTDKDENKQIALGTSKLNYIDPRITVAWCKKF 702
Query: 285 EVPIEKIFNQSLLAKFTWAMDV 220
EVP+EK+F ++ KF WA+D+
Sbjct: 703 EVPLEKVFTKTHREKFRWAIDM 724
[112][TOP]
>UniRef100_O17966 DNA topoisomerase 1 n=1 Tax=Caenorhabditis elegans RepID=TOP1_CAEEL
Length = 806
Score = 83.2 bits (204), Expect = 8e-15
Identities = 35/82 (42%), Positives = 56/82 (68%)
Frame = -1
Query: 465 KKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRH 286
K + E +KK + +++K++ K++ K +ALGTS++NY+DPRITVAWCK+
Sbjct: 715 KSARGAEKEKAQKKYDRLKEQLKKLKISRTDKDENKQIALGTSKLNYIDPRITVAWCKKF 774
Query: 285 EVPIEKIFNQSLLAKFTWAMDV 220
EVP+EK+F ++ KF WA+D+
Sbjct: 775 EVPLEKVFTKTHREKFRWAIDM 796
[113][TOP]
>UniRef100_UPI00017582B6 PREDICTED: similar to conserved hypothetical protein n=1
Tax=Tribolium castaneum RepID=UPI00017582B6
Length = 936
Score = 82.8 bits (203), Expect = 1e-14
Identities = 38/90 (42%), Positives = 62/90 (68%), Gaps = 1/90 (1%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ + +K + + ++ K++ +++ KT+ALGTS++NYLDPRI+VAWCK+
Sbjct: 847 GSVKEKTVYDKKKKMLQRLKEQLTKLEIQETDRDENKTIALGTSKLNYLDPRISVAWCKK 906
Query: 288 HEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKI+N++ KF WA+D+ PD+ F
Sbjct: 907 YGVPIEKIYNKTQRDKFRWAIDMAGPDYVF 936
[114][TOP]
>UniRef100_Q1ED17 Topoisomerase (DNA) I, like n=1 Tax=Danio rerio RepID=Q1ED17_DANRE
Length = 758
Score = 82.8 bits (203), Expect = 1e-14
Identities = 40/91 (43%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + EA +K + + ++ K++ +E+ K +ALGTS++NYLDPRI+VAWCK
Sbjct: 670 DEKFKKAV--EAKKKALQRVEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCK 727
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ +PIEKI+N++ KF WA+D+ + D+ F
Sbjct: 728 KFGIPIEKIYNKTQREKFAWAIDMAEKDYEF 758
[115][TOP]
>UniRef100_C5DEP3 KLTH0C10890p n=1 Tax=Lachancea thermotolerans CBS 6340
RepID=C5DEP3_LACTC
Length = 756
Score = 82.8 bits (203), Expect = 1e-14
Identities = 41/88 (46%), Positives = 61/88 (69%), Gaps = 1/88 (1%)
Frame = -1
Query: 462 KKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHE 283
K + S+E L+ +I + +IE +K KED VALGTS+INY+DPR++V +CK++
Sbjct: 669 KTNSESAEKLKMQIEKLDQRIETATIQLKDKEDNSQVALGTSKINYIDPRLSVVFCKKYG 728
Query: 282 VPIEKIFNQSLLAKFTWAMD-VDPDFRF 202
VPIEK+F +SL KF WA++ D ++RF
Sbjct: 729 VPIEKVFTKSLRDKFKWAIESADENWRF 756
[116][TOP]
>UniRef100_A7TJW1 Putative uncharacterized protein n=1 Tax=Vanderwaltozyma polyspora
DSM 70294 RepID=A7TJW1_VANPO
Length = 799
Score = 82.8 bits (203), Expect = 1e-14
Identities = 39/81 (48%), Positives = 58/81 (71%), Gaps = 1/81 (1%)
Frame = -1
Query: 441 EALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIF 262
E LEK I + +I+ +K KE+ V+LGTS+INY+DPR++V +CK+ ++PIEKIF
Sbjct: 719 EKLEKNIEKLEQRIQTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKFDIPIEKIF 778
Query: 261 NQSLLAKFTWAMD-VDPDFRF 202
+SL KF WA++ VD ++RF
Sbjct: 779 TKSLREKFRWAIESVDENWRF 799
[117][TOP]
>UniRef100_UPI0000F2B3E5 PREDICTED: similar to topoisomerase I n=1 Tax=Monodelphis domestica
RepID=UPI0000F2B3E5
Length = 916
Score = 82.4 bits (202), Expect = 1e-14
Identities = 40/91 (43%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + E +K + + ++ K++ +E+ K +ALGTS++NYLDPRI+VAWCK
Sbjct: 828 DVKTKKVV--ETKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCK 885
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ +PIEKI+N++ KF WA+D+ D D+ F
Sbjct: 886 KWGIPIEKIYNKTQREKFAWAIDMADKDYEF 916
[118][TOP]
>UniRef100_UPI00017B27B1 UPI00017B27B1 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B27B1
Length = 751
Score = 82.4 bits (202), Expect = 1e-14
Identities = 39/91 (42%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRI+VAWCK
Sbjct: 663 DEKSKKAVESK--KKAVQRIEDQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCK 720
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ +PIEKI+N++ KF WA+D+ + D+ F
Sbjct: 721 KWGIPIEKIYNKTQREKFAWAIDMAEKDYEF 751
[119][TOP]
>UniRef100_UPI00017B27B0 UPI00017B27B0 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B27B0
Length = 751
Score = 82.4 bits (202), Expect = 1e-14
Identities = 39/91 (42%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRI+VAWCK
Sbjct: 663 DEKSKKAVESK--KKAVQRIEDQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCK 720
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ +PIEKI+N++ KF WA+D+ + D+ F
Sbjct: 721 KWGIPIEKIYNKTQREKFAWAIDMAEKDYEF 751
[120][TOP]
>UniRef100_UPI00016E5C65 UPI00016E5C65 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5C65
Length = 755
Score = 82.4 bits (202), Expect = 1e-14
Identities = 39/91 (42%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + EA +K + + ++ K++ +E+ K +ALGTS++NYLDPRI+VAWCK
Sbjct: 667 DEKSKKAV--EAKKKAVQRIDDQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCK 724
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ +P+EKI+N++ KF WA+D+ + D+ F
Sbjct: 725 KWGIPVEKIYNKTQREKFAWAIDMAEDDYEF 755
[121][TOP]
>UniRef100_Q90WS1 Topoisomerase I beta n=1 Tax=Takifugu rubripes RepID=Q90WS1_TAKRU
Length = 753
Score = 82.4 bits (202), Expect = 1e-14
Identities = 39/91 (42%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + EA +K + + ++ K++ +E+ K +ALGTS++NYLDPRI+VAWCK
Sbjct: 665 DEKSKKAV--EAKKKAVQRIDDQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCK 722
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ +P+EKI+N++ KF WA+D+ + D+ F
Sbjct: 723 KWGIPVEKIYNKTQREKFAWAIDMAEDDYEF 753
[122][TOP]
>UniRef100_Q4SR65 Chromosome 11 SCAF14528, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4SR65_TETNG
Length = 806
Score = 82.4 bits (202), Expect = 1e-14
Identities = 39/91 (42%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRI+VAWCK
Sbjct: 718 DEKSKKAVESK--KKAVQRIEDQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCK 775
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ +PIEKI+N++ KF WA+D+ + D+ F
Sbjct: 776 KWGIPIEKIYNKTQREKFAWAIDMAEKDYEF 806
[123][TOP]
>UniRef100_B0XN02 Topoisomerase I n=2 Tax=Aspergillus fumigatus RepID=B0XN02_ASPFC
Length = 998
Score = 82.4 bits (202), Expect = 1e-14
Identities = 43/86 (50%), Positives = 59/86 (68%), Gaps = 1/86 (1%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K+ S E LE I++ +IE M+ + KED K VALGTS+INY+DPR+TV + K+ VP
Sbjct: 913 KSPSVEKLEAAITKLEQRIETMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVP 972
Query: 276 IEKIFNQSLLAKFTWAM-DVDPDFRF 202
IEK F++SL KF WA+ VD ++ F
Sbjct: 973 IEKFFSKSLREKFEWAIKSVDENWEF 998
[124][TOP]
>UniRef100_UPI000180B1AE PREDICTED: similar to DNA topoisomerase I, partial n=1 Tax=Ciona
intestinalis RepID=UPI000180B1AE
Length = 482
Score = 82.0 bits (201), Expect = 2e-14
Identities = 37/82 (45%), Positives = 56/82 (68%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K + E +KK+ + ++ K++ KE+ K +ALGTS++NYLDPRITVAWCK++ VP
Sbjct: 397 KRKAYEGKKKKVERLQEQLIKLEVQATDKEENKEIALGTSKLNYLDPRITVAWCKKYSVP 456
Query: 276 IEKIFNQSLLAKFTWAMDVDPD 211
IEK +N++ KF WA+ + D
Sbjct: 457 IEKCYNKTQRDKFAWAIAMVDD 478
[125][TOP]
>UniRef100_Q0UUB0 Putative uncharacterized protein n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UUB0_PHANO
Length = 887
Score = 82.0 bits (201), Expect = 2e-14
Identities = 42/86 (48%), Positives = 59/86 (68%), Gaps = 1/86 (1%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K + E LE I + + +IE M+ M+ KE K VALGTS+INY+DPR+TV + K+ +VP
Sbjct: 802 KGPTVEKLEANIDKINQRIENMRIQMEDKEGNKEVALGTSKINYIDPRLTVVFSKKFDVP 861
Query: 276 IEKIFNQSLLAKFTWAM-DVDPDFRF 202
IEK F+++L KF WA+ VD D+ F
Sbjct: 862 IEKFFSKTLREKFDWAIKSVDEDWEF 887
[126][TOP]
>UniRef100_C5DTC9 ZYRO0C07458p n=1 Tax=Zygosaccharomyces rouxii CBS 732
RepID=C5DTC9_ZYGRC
Length = 843
Score = 82.0 bits (201), Expect = 2e-14
Identities = 40/88 (45%), Positives = 61/88 (69%), Gaps = 1/88 (1%)
Frame = -1
Query: 462 KKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHE 283
K + S E LEK+I + +IE ++ KE+ V+LGTS+INY+DPR++V +CK++
Sbjct: 756 KSSSNSIEKLEKQIEKLDQRIETSSIQLRDKEENSQVSLGTSKINYIDPRLSVVFCKKYG 815
Query: 282 VPIEKIFNQSLLAKFTWAMD-VDPDFRF 202
VPIE+IF +SL KF WA++ D ++RF
Sbjct: 816 VPIERIFTKSLREKFKWAIESADENWRF 843
[127][TOP]
>UniRef100_B6JVY3 DNA topoisomerase I n=1 Tax=Schizosaccharomyces japonicus yFS275
RepID=B6JVY3_SCHJY
Length = 654
Score = 82.0 bits (201), Expect = 2e-14
Identities = 36/82 (43%), Positives = 57/82 (69%)
Frame = -1
Query: 447 SSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEK 268
S+E LEK++ + +I+ M + K++ KT ALGTS+INY+DPR+T + CKR +PIEK
Sbjct: 573 SNEQLEKRLIKMDERIKVMSNSIIDKDENKTTALGTSKINYIDPRLTFSLCKRENIPIEK 632
Query: 267 IFNQSLLAKFTWAMDVDPDFRF 202
+F++++ KF WA D D+ +
Sbjct: 633 LFSKTIRDKFNWAADTPADWNW 654
[128][TOP]
>UniRef100_B6H1W4 Pc13g03270 protein n=1 Tax=Penicillium chrysogenum Wisconsin 54-1255
RepID=B6H1W4_PENCW
Length = 864
Score = 82.0 bits (201), Expect = 2e-14
Identities = 40/81 (49%), Positives = 57/81 (70%), Gaps = 1/81 (1%)
Frame = -1
Query: 441 EALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIF 262
E LE I++ ++E M + KED K VALGTS+INY+DPR+TV + K+++VPIEK F
Sbjct: 784 EKLENSINKIDQRVETMSVQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKYDVPIEKFF 843
Query: 261 NQSLLAKFTWAM-DVDPDFRF 202
+++L KF WA+ VD D+ F
Sbjct: 844 SKALREKFEWAIKSVDEDWEF 864
[129][TOP]
>UniRef100_B4MU44 GK23720 n=1 Tax=Drosophila willistoni RepID=B4MU44_DROWI
Length = 638
Score = 81.6 bits (200), Expect = 2e-14
Identities = 41/97 (42%), Positives = 64/97 (65%), Gaps = 9/97 (9%)
Frame = -1
Query: 465 KKKKNLSSEALEKKISQTHAK--------IEKMQRDMKTKEDLKTVALGTSQINYLDPRI 310
K+ LS A +KKI++ K ++K++ + +E+ K VAL TS++NY+DPRI
Sbjct: 531 KRSATLSGTAKDKKIAECKGKQLERLKDQLKKLKLEETNREENKCVALTTSKLNYIDPRI 590
Query: 309 TVAWCKRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+VAWCK++ VPIEKIFN++ KF WA+ + D ++ F
Sbjct: 591 SVAWCKKNNVPIEKIFNKTQRTKFLWAIHMADENYHF 627
[130][TOP]
>UniRef100_A8Q2Z1 DNA topoisomerase I, putative n=1 Tax=Brugia malayi
RepID=A8Q2Z1_BRUMA
Length = 751
Score = 81.6 bits (200), Expect = 2e-14
Identities = 34/82 (41%), Positives = 57/82 (69%)
Frame = -1
Query: 465 KKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRH 286
K + + + K++ + ++ K++ K++ K +AL TS++NYLDPRI+VAWCK++
Sbjct: 663 KAHSDTAKQRATKRVDRVKEQLRKLKIQRTDKDENKQIALSTSKLNYLDPRISVAWCKKY 722
Query: 285 EVPIEKIFNQSLLAKFTWAMDV 220
+VPIEKIFN++ KF WA+D+
Sbjct: 723 QVPIEKIFNKTQREKFRWAIDM 744
[131][TOP]
>UniRef100_Q875K2 Topoisomerase I n=1 Tax=Emericella nidulans RepID=Q875K2_EMENI
Length = 871
Score = 81.6 bits (200), Expect = 2e-14
Identities = 41/81 (50%), Positives = 57/81 (70%), Gaps = 1/81 (1%)
Frame = -1
Query: 441 EALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIF 262
E LE I++ +IE M+ + KED K VALGTS+INY+DPR+TV + K+ +VPIEK F
Sbjct: 791 EKLEASITKLQQRIENMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFKVPIEKFF 850
Query: 261 NQSLLAKFTWAM-DVDPDFRF 202
++SL KF WA+ VD ++ F
Sbjct: 851 SKSLREKFEWAIKSVDENWEF 871
[132][TOP]
>UniRef100_Q6FNH4 Similar to uniprot|P04786 Saccharomyces cerevisiae YOL006c TOP1 DNA
topoisomerase I n=1 Tax=Candida glabrata
RepID=Q6FNH4_CANGA
Length = 744
Score = 81.6 bits (200), Expect = 2e-14
Identities = 38/83 (45%), Positives = 59/83 (71%), Gaps = 1/83 (1%)
Frame = -1
Query: 447 SSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEK 268
S E LEK++ + +I+ +K KE+ V+LGTS+INY+DPR++V +CK++ VPIEK
Sbjct: 662 SVEKLEKQVEKLEERIKTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKYNVPIEK 721
Query: 267 IFNQSLLAKFTWAMD-VDPDFRF 202
IF ++L KF WA++ D ++RF
Sbjct: 722 IFTKTLREKFAWAIESADENWRF 744
[133][TOP]
>UniRef100_O13463 Topoisomerase I n=1 Tax=Emericella nidulans RepID=O13463_EMENI
Length = 871
Score = 81.6 bits (200), Expect = 2e-14
Identities = 41/81 (50%), Positives = 57/81 (70%), Gaps = 1/81 (1%)
Frame = -1
Query: 441 EALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIF 262
E LE I++ +IE M+ + KED K VALGTS+INY+DPR+TV + K+ +VPIEK F
Sbjct: 791 EKLEASITKLQQRIENMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFKVPIEKFF 850
Query: 261 NQSLLAKFTWAM-DVDPDFRF 202
++SL KF WA+ VD ++ F
Sbjct: 851 SKSLREKFEWAIKSVDENWEF 871
[134][TOP]
>UniRef100_C8VUK1 Topoisomerase I [Source:UniProtKB/TrEMBL;Acc:Q875K2] n=2
Tax=Emericella nidulans RepID=C8VUK1_EMENI
Length = 871
Score = 81.6 bits (200), Expect = 2e-14
Identities = 41/81 (50%), Positives = 57/81 (70%), Gaps = 1/81 (1%)
Frame = -1
Query: 441 EALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIF 262
E LE I++ +IE M+ + KED K VALGTS+INY+DPR+TV + K+ +VPIEK F
Sbjct: 791 EKLEASITKLQQRIENMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFKVPIEKFF 850
Query: 261 NQSLLAKFTWAM-DVDPDFRF 202
++SL KF WA+ VD ++ F
Sbjct: 851 SKSLREKFEWAIKSVDENWEF 871
[135][TOP]
>UniRef100_C4JVV4 DNA topoisomerase I n=1 Tax=Uncinocarpus reesii 1704
RepID=C4JVV4_UNCRE
Length = 889
Score = 81.6 bits (200), Expect = 2e-14
Identities = 40/86 (46%), Positives = 59/86 (68%), Gaps = 1/86 (1%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K ++ E LE +++ +IE M + KE+ K VALGTS+INY+DPR+TV + K+ +VP
Sbjct: 804 KGMTIEKLENNLAKLDQRIETMSLQAQDKEENKEVALGTSKINYIDPRLTVVFSKKFDVP 863
Query: 276 IEKIFNQSLLAKFTWAM-DVDPDFRF 202
IEK F+++L KF WA+ VD D+ F
Sbjct: 864 IEKFFSKTLREKFDWAIKSVDEDWEF 889
[136][TOP]
>UniRef100_UPI0001760D92 PREDICTED: similar to topoisomerase (DNA) I, like n=1 Tax=Danio
rerio RepID=UPI0001760D92
Length = 748
Score = 81.3 bits (199), Expect = 3e-14
Identities = 40/91 (43%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + E +K + + ++ K++ +E+ K +ALGTS++NYLDPRI+V+WCK
Sbjct: 660 DEKSKKAV--ETKKKAVQRISEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVSWCK 717
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ VPIEKI++++ KF WA+D+ D DF F
Sbjct: 718 KWGVPIEKIYSKTQRDKFAWAIDMADEDFEF 748
[137][TOP]
>UniRef100_C5L755 DNA topoisomerase I, putative n=1 Tax=Perkinsus marinus ATCC 50983
RepID=C5L755_9ALVE
Length = 647
Score = 81.3 bits (199), Expect = 3e-14
Identities = 40/88 (45%), Positives = 59/88 (67%)
Frame = -1
Query: 465 KKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRH 286
K +K+ + ++L +KI E+ + + KED KTV+L TS+INY+DPRI+VA+CK H
Sbjct: 560 KLEKSNNMDSLVRKIKSQKLAAERTKIQIADKEDNKTVSLTTSKINYMDPRISVAFCKSH 619
Query: 285 EVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
+ PIEKIF +++ KF WAM +RF
Sbjct: 620 DCPIEKIFAKTIRNKFPWAMHSKSTWRF 647
[138][TOP]
>UniRef100_Q2URN8 DNA topoisomerase I n=1 Tax=Aspergillus oryzae RepID=Q2URN8_ASPOR
Length = 881
Score = 81.3 bits (199), Expect = 3e-14
Identities = 42/86 (48%), Positives = 57/86 (66%), Gaps = 1/86 (1%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K + E LE I + +IE M+ + KED K VALGTS+INY+DPR+TV + K+ VP
Sbjct: 796 KGPTVEKLENAIQKLEQRIETMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVP 855
Query: 276 IEKIFNQSLLAKFTWAM-DVDPDFRF 202
IEK F++SL KF WA+ V+ D+ F
Sbjct: 856 IEKFFSKSLREKFEWAIKSVEQDWEF 881
[139][TOP]
>UniRef100_B8MY66 Topoisomerase I n=1 Tax=Aspergillus flavus NRRL3357
RepID=B8MY66_ASPFN
Length = 881
Score = 81.3 bits (199), Expect = 3e-14
Identities = 42/86 (48%), Positives = 57/86 (66%), Gaps = 1/86 (1%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K + E LE I + +IE M+ + KED K VALGTS+INY+DPR+TV + K+ VP
Sbjct: 796 KGPTVEKLENAIQKLEQRIETMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVP 855
Query: 276 IEKIFNQSLLAKFTWAM-DVDPDFRF 202
IEK F++SL KF WA+ V+ D+ F
Sbjct: 856 IEKFFSKSLREKFEWAIKSVEQDWEF 881
[140][TOP]
>UniRef100_A1D4R5 Topoisomerase I n=1 Tax=Neosartorya fischeri NRRL 181
RepID=A1D4R5_NEOFI
Length = 886
Score = 81.3 bits (199), Expect = 3e-14
Identities = 42/86 (48%), Positives = 59/86 (68%), Gaps = 1/86 (1%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K+ S E LE I++ +IE M+ + KE+ K VALGTS+INY+DPR+TV + K+ VP
Sbjct: 801 KSSSVEKLEAAITKLEQRIETMELQAQDKEENKEVALGTSKINYIDPRLTVVFSKKFNVP 860
Query: 276 IEKIFNQSLLAKFTWAM-DVDPDFRF 202
IEK F++SL KF WA+ VD ++ F
Sbjct: 861 IEKFFSKSLREKFEWAIKSVDENWEF 886
[141][TOP]
>UniRef100_P79994 DNA topoisomerase I n=2 Tax=Gallus gallus RepID=P79994_CHICK
Length = 766
Score = 80.5 bits (197), Expect = 5e-14
Identities = 38/91 (41%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +AL TS++NYLDPRI+VAWCK
Sbjct: 678 DEKSKKAVESK--KKAVQRIEEQLMKLEVQATDREENKQIALSTSKLNYLDPRISVAWCK 735
Query: 291 RHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
+ +PIEKI+N++ KF WA+D+ + D+ F
Sbjct: 736 KWGIPIEKIYNKTQREKFAWAIDMAEEDYEF 766
[142][TOP]
>UniRef100_Q7QH57 AGAP004078-PA n=1 Tax=Anopheles gambiae RepID=Q7QH57_ANOGA
Length = 969
Score = 80.5 bits (197), Expect = 5e-14
Identities = 34/70 (48%), Positives = 54/70 (77%)
Frame = -1
Query: 429 KKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIFNQSL 250
K++ + +++K++ +++ KT+ALGTS++NYLDPRI+VAWCK+ VPIEKIFN++
Sbjct: 893 KQLERLKEQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKFGVPIEKIFNKTQ 952
Query: 249 LAKFTWAMDV 220
KF WA+D+
Sbjct: 953 RDKFRWAIDM 962
[143][TOP]
>UniRef100_Q75CB7 ACL008Cp n=1 Tax=Eremothecium gossypii RepID=Q75CB7_ASHGO
Length = 732
Score = 80.5 bits (197), Expect = 5e-14
Identities = 38/83 (45%), Positives = 59/83 (71%), Gaps = 1/83 (1%)
Frame = -1
Query: 447 SSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEK 268
S E L+ +I + +I MK KED TVAL TS+I+Y+DPR++VA+CK+++VP+EK
Sbjct: 650 SVEKLKAQIDKLEQRIRTTSIQMKDKEDNSTVALSTSKISYIDPRLSVAFCKKYDVPLEK 709
Query: 267 IFNQSLLAKFTWAMD-VDPDFRF 202
+F ++L KF WA++ D ++RF
Sbjct: 710 VFTKTLREKFKWAIESADENWRF 732
[144][TOP]
>UniRef100_Q0CUT4 DNA topoisomerase I n=1 Tax=Aspergillus terreus NIH2624
RepID=Q0CUT4_ASPTN
Length = 872
Score = 80.5 bits (197), Expect = 5e-14
Identities = 40/81 (49%), Positives = 55/81 (67%), Gaps = 1/81 (1%)
Frame = -1
Query: 441 EALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIF 262
E +E I + +IE M+ + KED K VALGTS+INY+DPR+TV + K+ VPIEK F
Sbjct: 792 EKIEANIQKLEQRIETMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFF 851
Query: 261 NQSLLAKFTWAM-DVDPDFRF 202
+++L KF WA+ VD D+ F
Sbjct: 852 SKALREKFEWAIKSVDEDWEF 872
[145][TOP]
>UniRef100_B3S6N7 Putative uncharacterized protein (Fragment) n=1 Tax=Trichoplax
adhaerens RepID=B3S6N7_TRIAD
Length = 560
Score = 80.1 bits (196), Expect = 7e-14
Identities = 38/88 (43%), Positives = 61/88 (69%), Gaps = 4/88 (4%)
Frame = -1
Query: 471 DGKKKKNLSSEAL----EKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITV 304
D K++K+ SS+ L +KK + ++ K+ K + K VAL TS++NY+DPRI+V
Sbjct: 466 DLKERKDESSKKLYEKRKKKTEMLNRQLHKLNLTETDKVENKEVALSTSKLNYMDPRISV 525
Query: 303 AWCKRHEVPIEKIFNQSLLAKFTWAMDV 220
AWCK++EVP+EK+FN++ KF WA+++
Sbjct: 526 AWCKKNEVPVEKVFNKTQREKFKWAIEM 553
[146][TOP]
>UniRef100_Q6CUB9 KLLA0C06116p n=1 Tax=Kluyveromyces lactis RepID=Q6CUB9_KLULA
Length = 785
Score = 80.1 bits (196), Expect = 7e-14
Identities = 35/73 (47%), Positives = 53/73 (72%)
Frame = -1
Query: 441 EALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIF 262
E L++ + + +I +K KED TVALGTS+INY+DPR++VA+CK+ +VPIEK+F
Sbjct: 705 EKLKQNVEKLEKRITNCSLQLKDKEDNSTVALGTSKINYIDPRLSVAFCKKFDVPIEKVF 764
Query: 261 NQSLLAKFTWAMD 223
++L KF WA++
Sbjct: 765 TKTLRDKFRWAIE 777
[147][TOP]
>UniRef100_C6HAF8 Topoisomerase I n=1 Tax=Ajellomyces capsulatus H143
RepID=C6HAF8_AJECH
Length = 909
Score = 80.1 bits (196), Expect = 7e-14
Identities = 40/86 (46%), Positives = 58/86 (67%), Gaps = 1/86 (1%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K ++ E LE ++ + +IE M + KE+ K VALGTS+INY+DPR+TV + K+ VP
Sbjct: 824 KGITIEKLENQLLKLSQRIENMSLQAEDKENNKEVALGTSKINYIDPRLTVVFSKKFNVP 883
Query: 276 IEKIFNQSLLAKFTWAM-DVDPDFRF 202
IEK F+++L KF WA+ VD D+ F
Sbjct: 884 IEKFFSKTLREKFDWAIKSVDEDWEF 909
[148][TOP]
>UniRef100_C0NC53 Topoisomerase I n=1 Tax=Ajellomyces capsulatus G186AR
RepID=C0NC53_AJECG
Length = 909
Score = 80.1 bits (196), Expect = 7e-14
Identities = 40/86 (46%), Positives = 58/86 (67%), Gaps = 1/86 (1%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K ++ E LE ++ + +IE M + KE+ K VALGTS+INY+DPR+TV + K+ VP
Sbjct: 824 KGITIEKLENQLLKLSQRIENMSLQAEDKENNKEVALGTSKINYIDPRLTVVFSKKFNVP 883
Query: 276 IEKIFNQSLLAKFTWAM-DVDPDFRF 202
IEK F+++L KF WA+ VD D+ F
Sbjct: 884 IEKFFSKTLREKFDWAIKSVDEDWEF 909
[149][TOP]
>UniRef100_UPI00017968A4 PREDICTED: similar to TOP1MT protein n=1 Tax=Equus caballus
RepID=UPI00017968A4
Length = 655
Score = 79.7 bits (195), Expect = 9e-14
Identities = 36/81 (44%), Positives = 55/81 (67%), Gaps = 1/81 (1%)
Frame = -1
Query: 441 EALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIF 262
E E+ + + ++ ++ KE+ K VALGTS++NYLDPRI+VAWCKR VP+E+I+
Sbjct: 575 EKRERLLEKLEEQLMRLSTQATDKEESKQVALGTSKLNYLDPRISVAWCKRFGVPVERIY 634
Query: 261 NQSLLAKFTWAMDV-DPDFRF 202
N++ +F WA+D+ DF F
Sbjct: 635 NKTQRERFAWALDMAGEDFEF 655
[150][TOP]
>UniRef100_UPI000176075D PREDICTED: similar to DNA topoisomerase I n=1 Tax=Danio rerio
RepID=UPI000176075D
Length = 531
Score = 79.7 bits (195), Expect = 9e-14
Identities = 37/81 (45%), Positives = 57/81 (70%), Gaps = 1/81 (1%)
Frame = -1
Query: 441 EALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIF 262
E +K + + ++ KM+ +E+ K +AL TS++NYLDPRI+VAWCK EVP++KI+
Sbjct: 451 EKKKKAVQRCEEQLLKMEVQATDREENKQIALSTSKLNYLDPRISVAWCKNMEVPLDKIY 510
Query: 261 NQSLLAKFTWAMDV-DPDFRF 202
N++L KF WA+D+ + DF F
Sbjct: 511 NKTLRDKFAWAVDMTELDFVF 531
[151][TOP]
>UniRef100_UPI0000E48333 PREDICTED: similar to topoisomerase I alpha isoform 3, partial n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000E48333
Length = 440
Score = 79.7 bits (195), Expect = 9e-14
Identities = 41/83 (49%), Positives = 60/83 (72%), Gaps = 4/83 (4%)
Frame = -1
Query: 438 ALEKKISQTHAKIEKMQR-DMKT--KEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEK 268
A+EKK Q +E++ + +MK KE+ K +ALGTS++NYLDPRI+VAW K+ +VPIEK
Sbjct: 358 AMEKKAKQVERLVEQLAKLEMKATDKEENKEIALGTSKLNYLDPRISVAWTKKWDVPIEK 417
Query: 267 IFNQSLLAKFTWAMDV-DPDFRF 202
++N++ KF WA+D+ DF F
Sbjct: 418 VYNKTQRDKFRWAVDMAGADFVF 440
[152][TOP]
>UniRef100_UPI0000E471B7 PREDICTED: similar to topoisomerase I beta n=1 Tax=Strongylocentrotus
purpuratus RepID=UPI0000E471B7
Length = 879
Score = 79.7 bits (195), Expect = 9e-14
Identities = 41/83 (49%), Positives = 60/83 (72%), Gaps = 4/83 (4%)
Frame = -1
Query: 438 ALEKKISQTHAKIEKMQR-DMKT--KEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEK 268
A+EKK Q +E++ + +MK KE+ K +ALGTS++NYLDPRI+VAW K+ +VPIEK
Sbjct: 797 AMEKKAKQVERLVEQLAKLEMKATDKEENKEIALGTSKLNYLDPRISVAWTKKWDVPIEK 856
Query: 267 IFNQSLLAKFTWAMDV-DPDFRF 202
++N++ KF WA+D+ DF F
Sbjct: 857 VYNKTQRDKFRWAVDMAGADFVF 879
[153][TOP]
>UniRef100_UPI0001A2C88D UPI0001A2C88D related cluster n=1 Tax=Danio rerio
RepID=UPI0001A2C88D
Length = 609
Score = 79.7 bits (195), Expect = 9e-14
Identities = 37/81 (45%), Positives = 57/81 (70%), Gaps = 1/81 (1%)
Frame = -1
Query: 441 EALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIF 262
E +K + + ++ KM+ +E+ K +AL TS++NYLDPRI+VAWCK EVP++KI+
Sbjct: 529 EKKKKAVQRCEEQLLKMEVQATDREENKQIALSTSKLNYLDPRISVAWCKNMEVPLDKIY 588
Query: 261 NQSLLAKFTWAMDV-DPDFRF 202
N++L KF WA+D+ + DF F
Sbjct: 589 NKTLRDKFAWAVDMTELDFVF 609
[154][TOP]
>UniRef100_Q94705 DNA topoisomerase I n=1 Tax=Physarum polycephalum RepID=Q94705_PHYPO
Length = 1015
Score = 79.7 bits (195), Expect = 9e-14
Identities = 43/95 (45%), Positives = 59/95 (62%), Gaps = 2/95 (2%)
Frame = -1
Query: 480 KSPDGKKKKNL--SSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRIT 307
++P K K+ L S E + I + I K K++LK+VAL TS+INY+DPRIT
Sbjct: 921 ETPKKKVKRALPDSVEKCKAAIERVDTSINKWNIKKTEKDELKSVALTTSKINYIDPRIT 980
Query: 306 VAWCKRHEVPIEKIFNQSLLAKFTWAMDVDPDFRF 202
AW KR + I K+F++SL KF WAMDV+ D+ F
Sbjct: 981 AAWAKRVGLDIGKLFSKSLREKFPWAMDVEEDWEF 1015
[155][TOP]
>UniRef100_B8MH68 Topoisomerase I n=1 Tax=Talaromyces stipitatus ATCC 10500
RepID=B8MH68_TALSN
Length = 864
Score = 79.7 bits (195), Expect = 9e-14
Identities = 40/86 (46%), Positives = 57/86 (66%), Gaps = 1/86 (1%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K + E LE +++ +IE M + KE+ K VALGTS+INY+DPR+TV + K+ VP
Sbjct: 779 KGQTIEKLENNVAKLEQRIETMSLQAEDKENNKEVALGTSKINYIDPRLTVVFTKKFNVP 838
Query: 276 IEKIFNQSLLAKFTWAM-DVDPDFRF 202
IEK F+++L KF WA+ VD D+ F
Sbjct: 839 IEKFFSKTLREKFDWAIKSVDEDWEF 864
[156][TOP]
>UniRef100_A2Q8K2 Catalytic activity: ATP-independent breakage of single-stranded DNA
n=1 Tax=Aspergillus niger CBS 513.88 RepID=A2Q8K2_ASPNC
Length = 884
Score = 79.7 bits (195), Expect = 9e-14
Identities = 39/81 (48%), Positives = 57/81 (70%), Gaps = 1/81 (1%)
Frame = -1
Query: 441 EALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIF 262
+ +E I++ +IE M+ + KE+ K VALGTS+INY+DPR+TV + K+ +VPIEK F
Sbjct: 804 DKIEAAITKLEQRIETMELQAQDKEENKEVALGTSKINYIDPRLTVVFSKKFDVPIEKFF 863
Query: 261 NQSLLAKFTWAM-DVDPDFRF 202
++SL KF WA+ VD D+ F
Sbjct: 864 SKSLREKFEWAIKSVDEDWEF 884
[157][TOP]
>UniRef100_C7GJV8 Top1p n=1 Tax=Saccharomyces cerevisiae JAY291 RepID=C7GJV8_YEAS2
Length = 745
Score = 79.3 bits (194), Expect = 1e-13
Identities = 36/83 (43%), Positives = 60/83 (72%), Gaps = 1/83 (1%)
Frame = -1
Query: 447 SSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEK 268
S E ++ ++ + +I+ +K KE+ V+LGTS+INY+DPR++V +CK+++VPIEK
Sbjct: 663 SVEKIKAQVEKLEQRIQTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKYDVPIEK 722
Query: 267 IFNQSLLAKFTWAMD-VDPDFRF 202
IF ++L KF WA++ VD ++RF
Sbjct: 723 IFTKTLREKFKWAIESVDENWRF 745
[158][TOP]
>UniRef100_B3LJ50 DNA topoisomerase I n=2 Tax=Saccharomyces cerevisiae
RepID=B3LJ50_YEAS1
Length = 769
Score = 79.3 bits (194), Expect = 1e-13
Identities = 36/83 (43%), Positives = 60/83 (72%), Gaps = 1/83 (1%)
Frame = -1
Query: 447 SSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEK 268
S E ++ ++ + +I+ +K KE+ V+LGTS+INY+DPR++V +CK+++VPIEK
Sbjct: 687 SVEKIKAQVEKLEQRIQTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKYDVPIEK 746
Query: 267 IFNQSLLAKFTWAMD-VDPDFRF 202
IF ++L KF WA++ VD ++RF
Sbjct: 747 IFTKTLREKFKWAIESVDENWRF 769
[159][TOP]
>UniRef100_A1CRV8 Topoisomerase I n=1 Tax=Aspergillus clavatus RepID=A1CRV8_ASPCL
Length = 886
Score = 79.3 bits (194), Expect = 1e-13
Identities = 41/86 (47%), Positives = 58/86 (67%), Gaps = 1/86 (1%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K+ S +E I++ +IE M+ + KED K VALGTS+INY+DPR+TV + K+ VP
Sbjct: 801 KSPSVARIEAAITKLEQRIETMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVP 860
Query: 276 IEKIFNQSLLAKFTWAM-DVDPDFRF 202
IEK F++SL KF WA+ VD ++ F
Sbjct: 861 IEKFFSKSLREKFEWAIKSVDENWEF 886
[160][TOP]
>UniRef100_P04786 DNA topoisomerase 1 n=3 Tax=Saccharomyces cerevisiae
RepID=TOP1_YEAST
Length = 769
Score = 79.3 bits (194), Expect = 1e-13
Identities = 36/83 (43%), Positives = 60/83 (72%), Gaps = 1/83 (1%)
Frame = -1
Query: 447 SSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEK 268
S E ++ ++ + +I+ +K KE+ V+LGTS+INY+DPR++V +CK+++VPIEK
Sbjct: 687 SVEKIKAQVEKLEQRIQTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKYDVPIEK 746
Query: 267 IFNQSLLAKFTWAMD-VDPDFRF 202
IF ++L KF WA++ VD ++RF
Sbjct: 747 IFTKTLREKFKWAIESVDENWRF 769
[161][TOP]
>UniRef100_Q6FVE9 Similar to uniprot|P04786 Saccharomyces cerevisiae YOL006c TOP1 DNA
topoisomerase I n=1 Tax=Candida glabrata
RepID=Q6FVE9_CANGA
Length = 717
Score = 79.0 bits (193), Expect = 2e-13
Identities = 40/83 (48%), Positives = 57/83 (68%), Gaps = 1/83 (1%)
Frame = -1
Query: 447 SSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEK 268
S E LEK I + +I Q ++ +E V+LGTS+INY+DPR++V +CK++ VPIEK
Sbjct: 635 SVEKLEKAIERLDQRISTSQVQLQDREANSEVSLGTSKINYIDPRLSVVFCKKYGVPIEK 694
Query: 267 IFNQSLLAKFTWAMD-VDPDFRF 202
IF +SL KF WA++ VD +RF
Sbjct: 695 IFTKSLREKFKWAIESVDETWRF 717
[162][TOP]
>UniRef100_O59891 Topoisomerase I n=1 Tax=Cryptococcus neoformans var. neoformans
RepID=O59891_CRYNE
Length = 844
Score = 79.0 bits (193), Expect = 2e-13
Identities = 37/87 (42%), Positives = 60/87 (68%), Gaps = 1/87 (1%)
Frame = -1
Query: 459 KKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEV 280
K+ + E L +I++ +I + ++ ++ LK VALGTS+INY+DPR+TVAW K+ +V
Sbjct: 758 KRGATEEKLLAQIARIDERIATAKVQLQDRDKLKDVALGTSKINYIDPRLTVAWAKKFDV 817
Query: 279 PIEKIFNQSLLAKFTWA-MDVDPDFRF 202
P+EK+F+++L KF WA + PD+ F
Sbjct: 818 PLEKLFSKTLREKFPWAEAEAGPDWVF 844
[163][TOP]
>UniRef100_UPI00017B3173 UPI00017B3173 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B3173
Length = 622
Score = 78.6 bits (192), Expect = 2e-13
Identities = 36/85 (42%), Positives = 57/85 (67%), Gaps = 2/85 (2%)
Frame = -1
Query: 468 GKKKKNLSSEALEKK--ISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWC 295
G L + + KK + + ++ K++ +E+ K +ALGTS++NYLDPRI+VAWC
Sbjct: 531 GSADAKLQALVVRKKMAVKRCEEQLLKLEVQATDREENKQIALGTSKLNYLDPRISVAWC 590
Query: 294 KRHEVPIEKIFNQSLLAKFTWAMDV 220
K+ EVP++KI+N+S KF WA+D+
Sbjct: 591 KKMEVPVDKIYNKSQRDKFAWAIDM 615
[164][TOP]
>UniRef100_Q4SKE8 Chromosome 13 SCAF14566, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4SKE8_TETNG
Length = 622
Score = 78.6 bits (192), Expect = 2e-13
Identities = 36/85 (42%), Positives = 57/85 (67%), Gaps = 2/85 (2%)
Frame = -1
Query: 468 GKKKKNLSSEALEKK--ISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWC 295
G L + + KK + + ++ K++ +E+ K +ALGTS++NYLDPRI+VAWC
Sbjct: 531 GSADAKLQALVVRKKMAVKRCEEQLLKLEVQATDREENKQIALGTSKLNYLDPRISVAWC 590
Query: 294 KRHEVPIEKIFNQSLLAKFTWAMDV 220
K+ EVP++KI+N+S KF WA+D+
Sbjct: 591 KKMEVPVDKIYNKSQRDKFAWAIDM 615
[165][TOP]
>UniRef100_Q5KB99 Topoisomerase I n=1 Tax=Filobasidiella neoformans RepID=Q5KB99_CRYNE
Length = 881
Score = 78.6 bits (192), Expect = 2e-13
Identities = 36/87 (41%), Positives = 60/87 (68%), Gaps = 1/87 (1%)
Frame = -1
Query: 459 KKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEV 280
K+ + E L ++++ +I + ++ ++ LK VALGTS+INY+DPR+TVAW K+ +V
Sbjct: 795 KRGATEEKLLAQVARIDERIATAKVQLQDRDKLKDVALGTSKINYIDPRLTVAWAKKFDV 854
Query: 279 PIEKIFNQSLLAKFTWA-MDVDPDFRF 202
P+EK+F+++L KF WA + PD+ F
Sbjct: 855 PLEKLFSKTLREKFPWAEAEAGPDWVF 881
[166][TOP]
>UniRef100_B6QNQ2 Topoisomerase I n=1 Tax=Penicillium marneffei ATCC 18224
RepID=B6QNQ2_PENMQ
Length = 860
Score = 78.6 bits (192), Expect = 2e-13
Identities = 39/86 (45%), Positives = 57/86 (66%), Gaps = 1/86 (1%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K + E LE +++ +IE M + KE+ K VALGTS+INY+DPR+TV + K+ VP
Sbjct: 775 KGQTVEKLENNVTKLEQRIENMSLQAEDKENNKEVALGTSKINYIDPRLTVVFTKKFNVP 834
Query: 276 IEKIFNQSLLAKFTWAM-DVDPDFRF 202
IEK F+++L KF WA+ V+ D+ F
Sbjct: 835 IEKFFSKTLREKFDWAIKSVEEDWEF 860
[167][TOP]
>UniRef100_A3LUX2 DNA topoisomerase I n=1 Tax=Pichia stipitis RepID=A3LUX2_PICST
Length = 780
Score = 78.6 bits (192), Expect = 2e-13
Identities = 38/87 (43%), Positives = 60/87 (68%), Gaps = 1/87 (1%)
Frame = -1
Query: 459 KKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEV 280
KKNL+ E L++++ +I +K KED V+LGTS++NY+DPR+TV + K+ +V
Sbjct: 694 KKNLTVEKLQQQVEVIENRIVTTTLQLKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFDV 753
Query: 279 PIEKIFNQSLLAKFTWAMD-VDPDFRF 202
PIEK+F ++L KF WA++ D ++RF
Sbjct: 754 PIEKLFTKTLRDKFKWAIESADENWRF 780
[168][TOP]
>UniRef100_Q4V7M4 MGC115546 protein n=1 Tax=Xenopus laevis RepID=Q4V7M4_XENLA
Length = 503
Score = 77.4 bits (189), Expect = 5e-13
Identities = 36/88 (40%), Positives = 60/88 (68%), Gaps = 1/88 (1%)
Frame = -1
Query: 462 KKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHE 283
+K N E+ ++ + +T ++ +M+ +E+ K +AL TS++NYLDPRI+VAWCK+
Sbjct: 416 EKLNKVVESKKRAVQRTEEQLMRMEVQATDREENKQIALSTSKLNYLDPRISVAWCKKWT 475
Query: 282 VPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
V +EKI+N++ KF WA+D+ + DF F
Sbjct: 476 VGLEKIYNKTYRDKFAWAIDMTETDFIF 503
[169][TOP]
>UniRef100_Q6C7R2 YALI0D26103p n=1 Tax=Yarrowia lipolytica RepID=Q6C7R2_YARLI
Length = 760
Score = 77.4 bits (189), Expect = 5e-13
Identities = 35/81 (43%), Positives = 56/81 (69%), Gaps = 1/81 (1%)
Frame = -1
Query: 441 EALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIF 262
E L ++ + ++ M+ +K KED +VALGTS++NY+DPR+TV + K+++VPIEK+F
Sbjct: 680 EKLRAQVEKLETRVTTMRMQLKDKEDNSSVALGTSKMNYIDPRLTVKFSKKYDVPIEKLF 739
Query: 261 NQSLLAKFTWAM-DVDPDFRF 202
++L KF WA+ D D+ F
Sbjct: 740 TKTLRDKFQWAIQSADEDWEF 760
[170][TOP]
>UniRef100_B3GD31 Topoisomerase I (Fragment) n=1 Tax=Sirdenus grayii
RepID=B3GD31_9CARA
Length = 247
Score = 77.0 bits (188), Expect = 6e-13
Identities = 34/77 (44%), Positives = 56/77 (72%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ L E +K + + +++K++ +++ KT+ALGTS++NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKLVYEKKKKMLDKLKDQLKKLEVQETDRDENKTIALGTSKLNYLDPRISVAWCKK 229
Query: 288 HEVPIEKIFNQSLLAKF 238
++VPIEKI+N++ KF
Sbjct: 230 YDVPIEKIYNKTQRDKF 246
[171][TOP]
>UniRef100_O60013 DNA topoisomerase I n=1 Tax=Pneumocystis carinii RepID=O60013_PNECA
Length = 763
Score = 77.0 bits (188), Expect = 6e-13
Identities = 35/87 (40%), Positives = 55/87 (63%)
Frame = -1
Query: 462 KKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHE 283
K + ++ E L+ +I + + +I +M+ M K KT ALGTS+INY+DPR+T AWC ++
Sbjct: 677 KTRGITIETLDLQIKKINERIHQMKALMIDKAQNKTTALGTSKINYIDPRLTYAWCAKYG 736
Query: 282 VPIEKIFNQSLLAKFTWAMDVDPDFRF 202
V IE++F ++L F WA D+ F
Sbjct: 737 VNIERVFTKTLRETFAWAASTTADWEF 763
[172][TOP]
>UniRef100_C5GB81 DNA topoisomerase I n=2 Tax=Ajellomyces dermatitidis
RepID=C5GB81_AJEDR
Length = 911
Score = 77.0 bits (188), Expect = 6e-13
Identities = 38/86 (44%), Positives = 58/86 (67%), Gaps = 1/86 (1%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K ++ E LE ++ + +IE M + +E+ K VALGTS+INY+DPR+TV + K+ VP
Sbjct: 826 KGVTIEKLENQLLKLSQRIENMSLQAEDRENNKEVALGTSKINYIDPRLTVVFSKKFNVP 885
Query: 276 IEKIFNQSLLAKFTWAM-DVDPDFRF 202
IEK F+++L KF WA+ V+ D+ F
Sbjct: 886 IEKFFSKTLREKFDWAIKSVEEDWEF 911
[173][TOP]
>UniRef100_B9WIH6 DNA topoisomerase, putative n=1 Tax=Candida dubliniensis CD36
RepID=B9WIH6_CANDC
Length = 777
Score = 76.6 bits (187), Expect = 8e-13
Identities = 37/86 (43%), Positives = 59/86 (68%), Gaps = 1/86 (1%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
KN + E L+++I +I + +K KED V+LGTS++NY+DPR+TV + K+ +VP
Sbjct: 692 KNATVEKLKQQIETLENRILNVSFQLKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFDVP 751
Query: 276 IEKIFNQSLLAKFTWAMD-VDPDFRF 202
IEK+F ++L KF WA++ D ++RF
Sbjct: 752 IEKLFTKTLREKFNWAIESTDENWRF 777
[174][TOP]
>UniRef100_B2WCA4 DNA topoisomerase 1 n=1 Tax=Pyrenophora tritici-repentis Pt-1C-BFP
RepID=B2WCA4_PYRTR
Length = 905
Score = 76.6 bits (187), Expect = 8e-13
Identities = 40/86 (46%), Positives = 57/86 (66%), Gaps = 1/86 (1%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K + E LE + + +IE M+ M+ KE K VALGTS+INY+DPR+TV + K+ VP
Sbjct: 820 KGPTVEKLEANVEKIVQRIENMKIQMEDKEGNKEVALGTSKINYIDPRLTVVFSKKFGVP 879
Query: 276 IEKIFNQSLLAKFTWAM-DVDPDFRF 202
IEK F+++L KF WA+ VD ++ F
Sbjct: 880 IEKFFSKTLREKFDWAIKSVDENWEF 905
[175][TOP]
>UniRef100_UPI00016E5A49 UPI00016E5A49 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5A49
Length = 692
Score = 76.3 bits (186), Expect = 1e-12
Identities = 38/94 (40%), Positives = 61/94 (64%), Gaps = 7/94 (7%)
Frame = -1
Query: 462 KKKNLSSEALEKKISQTHAKIEKMQRDMKT------KEDLKTVALGTSQINYLDPRITVA 301
K K S L+ + + A +++ ++ +K +E+ K +ALGTS++NYLDPRI+VA
Sbjct: 599 KAKGSSEFKLQTLVERKKAAVKRCEQLLKMEIQATDREENKQIALGTSKLNYLDPRISVA 658
Query: 300 WCKRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
WCK +P++KI+N+S KF WA+D+ + DF F
Sbjct: 659 WCKNMGLPVDKIYNKSQRDKFAWAIDMTEVDFEF 692
[176][TOP]
>UniRef100_UPI00016E5A48 UPI00016E5A48 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5A48
Length = 632
Score = 76.3 bits (186), Expect = 1e-12
Identities = 38/94 (40%), Positives = 61/94 (64%), Gaps = 7/94 (7%)
Frame = -1
Query: 462 KKKNLSSEALEKKISQTHAKIEKMQRDMKT------KEDLKTVALGTSQINYLDPRITVA 301
K K S L+ + + A +++ ++ +K +E+ K +ALGTS++NYLDPRI+VA
Sbjct: 539 KAKGSSEFKLQTLVERKKAAVKRCEQLLKMEIQATDREENKQIALGTSKLNYLDPRISVA 598
Query: 300 WCKRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
WCK +P++KI+N+S KF WA+D+ + DF F
Sbjct: 599 WCKNMGLPVDKIYNKSQRDKFAWAIDMTEVDFEF 632
[177][TOP]
>UniRef100_Q8TBP3 TOP1MT protein (Fragment) n=1 Tax=Homo sapiens RepID=Q8TBP3_HUMAN
Length = 101
Score = 76.3 bits (186), Expect = 1e-12
Identities = 40/92 (43%), Positives = 60/92 (65%), Gaps = 2/92 (2%)
Frame = -1
Query: 471 DGKKKKNLSSEA-LEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWC 295
DGK + L + L +K+ + A++ D KE+ K VALGTS++NYLDPRI++AWC
Sbjct: 13 DGKSRSVLEKKRRLLEKLQEQLAQLSVQATD---KEENKQVALGTSKLNYLDPRISIAWC 69
Query: 294 KRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
KR VP+EKI++++ +F WA+ + DF F
Sbjct: 70 KRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 101
[178][TOP]
>UniRef100_B7ZAR5 cDNA, FLJ79279, highly similar to DNA topoisomerase I,
mitochondrial(EC 5.99.1.2) n=1 Tax=Homo sapiens
RepID=B7ZAR5_HUMAN
Length = 503
Score = 76.3 bits (186), Expect = 1e-12
Identities = 40/92 (43%), Positives = 60/92 (65%), Gaps = 2/92 (2%)
Frame = -1
Query: 471 DGKKKKNLSSEA-LEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWC 295
DGK + L + L +K+ + A++ D KE+ K VALGTS++NYLDPRI++AWC
Sbjct: 415 DGKSRSVLEKKRWLLEKLQEQLAQLSVQATD---KEENKQVALGTSKLNYLDPRISIAWC 471
Query: 294 KRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
KR VP+EKI++++ +F WA+ + DF F
Sbjct: 472 KRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 503
[179][TOP]
>UniRef100_B7Z9E8 cDNA, FLJ78812, highly similar to DNA topoisomerase I,
mitochondrial (EC 5.99.1.2) n=1 Tax=Homo sapiens
RepID=B7Z9E8_HUMAN
Length = 503
Score = 76.3 bits (186), Expect = 1e-12
Identities = 40/92 (43%), Positives = 60/92 (65%), Gaps = 2/92 (2%)
Frame = -1
Query: 471 DGKKKKNLSSEA-LEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWC 295
DGK + L + L +K+ + A++ D KE+ K VALGTS++NYLDPRI++AWC
Sbjct: 415 DGKSRSVLEKKRWLLEKLQEQLAQLSVQATD---KEENKQVALGTSKLNYLDPRISIAWC 471
Query: 294 KRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
KR VP+EKI++++ +F WA+ + DF F
Sbjct: 472 KRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 503
[180][TOP]
>UniRef100_B4DYD2 cDNA FLJ50294, highly similar to DNA topoisomerase I, mitochondrial
(EC 5.99.1.2) n=1 Tax=Homo sapiens RepID=B4DYD2_HUMAN
Length = 503
Score = 76.3 bits (186), Expect = 1e-12
Identities = 40/92 (43%), Positives = 60/92 (65%), Gaps = 2/92 (2%)
Frame = -1
Query: 471 DGKKKKNLSSEA-LEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWC 295
DGK + L + L +K+ + A++ D KE+ K VALGTS++NYLDPRI++AWC
Sbjct: 415 DGKSRSVLEKKRRLLEKLQEQLAQLSVQATD---KEENKQVALGTSKLNYLDPRISIAWC 471
Query: 294 KRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
KR VP+EKI++++ +F WA+ + DF F
Sbjct: 472 KRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 503
[181][TOP]
>UniRef100_Q1DXZ1 Putative uncharacterized protein n=1 Tax=Coccidioides immitis
RepID=Q1DXZ1_COCIM
Length = 905
Score = 76.3 bits (186), Expect = 1e-12
Identities = 38/86 (44%), Positives = 56/86 (65%), Gaps = 1/86 (1%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K + E E +++ +I+ M + KED K VALGTS+INY+DPR+TV + K+ VP
Sbjct: 820 KGATIEKYENNLAKLDQRIDTMSLQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFSVP 879
Query: 276 IEKIFNQSLLAKFTWAM-DVDPDFRF 202
IEK F+++L KF WA+ VD ++ F
Sbjct: 880 IEKFFSKTLREKFDWAIKSVDENWEF 905
[182][TOP]
>UniRef100_C5P0Y8 DNA topoisomerase I, putative n=1 Tax=Coccidioides posadasii C735
delta SOWgp RepID=C5P0Y8_COCP7
Length = 905
Score = 76.3 bits (186), Expect = 1e-12
Identities = 38/86 (44%), Positives = 56/86 (65%), Gaps = 1/86 (1%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K + E E +++ +I+ M + KED K VALGTS+INY+DPR+TV + K+ VP
Sbjct: 820 KGATIEKYENNLAKLDQRIDTMSLQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFSVP 879
Query: 276 IEKIFNQSLLAKFTWAM-DVDPDFRF 202
IEK F+++L KF WA+ VD ++ F
Sbjct: 880 IEKFFSKTLREKFDWAIKSVDENWEF 905
[183][TOP]
>UniRef100_C5FTA8 DNA topoisomerase 1 n=1 Tax=Microsporum canis CBS 113480
RepID=C5FTA8_NANOT
Length = 896
Score = 76.3 bits (186), Expect = 1e-12
Identities = 38/81 (46%), Positives = 55/81 (67%), Gaps = 1/81 (1%)
Frame = -1
Query: 441 EALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIF 262
E E +IS+ +IE M + KE+ K VALGTS++NY+DPR+TV + K+ VPIEK F
Sbjct: 816 EKFEGQISKIDQRIENMLLQAEDKENNKEVALGTSKLNYIDPRLTVVFSKKFNVPIEKFF 875
Query: 261 NQSLLAKFTWAM-DVDPDFRF 202
++++ KF WA+ VD D+ F
Sbjct: 876 SKTMREKFDWAIKSVDEDWEF 896
[184][TOP]
>UniRef100_C4XZS7 Putative uncharacterized protein n=1 Tax=Clavispora lusitaniae ATCC
42720 RepID=C4XZS7_CLAL4
Length = 764
Score = 76.3 bits (186), Expect = 1e-12
Identities = 38/86 (44%), Positives = 57/86 (66%), Gaps = 1/86 (1%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K S E L+ +I + +I +K KED V+LGTS++NY+DPR+TV + K+ VP
Sbjct: 679 KGASVEKLKVQIEKIENRILNTNFQLKDKEDNSEVSLGTSKLNYIDPRLTVMFAKKFNVP 738
Query: 276 IEKIFNQSLLAKFTWAMD-VDPDFRF 202
IEK+F ++L KFTWA++ D ++RF
Sbjct: 739 IEKLFTKTLREKFTWAIESADENWRF 764
[185][TOP]
>UniRef100_A9Q1D5 DNA topoisomerase I, mitochondrial n=1 Tax=Pan troglodytes
RepID=TOP1M_PANTR
Length = 601
Score = 76.3 bits (186), Expect = 1e-12
Identities = 40/92 (43%), Positives = 60/92 (65%), Gaps = 2/92 (2%)
Frame = -1
Query: 471 DGKKKKNLSSEA-LEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWC 295
DGK + L + L +K+ + A++ D KE+ K VALGTS++NYLDPRI++AWC
Sbjct: 513 DGKSRSVLEKKRRLLEKLQEQLAQLSVQATD---KEENKQVALGTSKLNYLDPRISIAWC 569
Query: 294 KRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
KR VP+EKI++++ +F WA+ + DF F
Sbjct: 570 KRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 601
[186][TOP]
>UniRef100_Q969P6 DNA topoisomerase I, mitochondrial n=1 Tax=Homo sapiens
RepID=TOP1M_HUMAN
Length = 601
Score = 76.3 bits (186), Expect = 1e-12
Identities = 40/92 (43%), Positives = 60/92 (65%), Gaps = 2/92 (2%)
Frame = -1
Query: 471 DGKKKKNLSSEA-LEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWC 295
DGK + L + L +K+ + A++ D KE+ K VALGTS++NYLDPRI++AWC
Sbjct: 513 DGKSRSVLEKKRRLLEKLQEQLAQLSVQATD---KEENKQVALGTSKLNYLDPRISIAWC 569
Query: 294 KRHEVPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
KR VP+EKI++++ +F WA+ + DF F
Sbjct: 570 KRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 601
[187][TOP]
>UniRef100_UPI000069E294 DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I). n=1
Tax=Xenopus (Silurana) tropicalis RepID=UPI000069E294
Length = 786
Score = 75.5 bits (184), Expect = 2e-12
Identities = 37/85 (43%), Positives = 57/85 (67%), Gaps = 3/85 (3%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRI+VAWCK
Sbjct: 696 DEKSKKLVESK--KKAVQRVEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCK 753
Query: 291 RHEVPIEKIFN---QSLLAKFTWAM 226
++ +PIEKI+N +SLL W M
Sbjct: 754 KYGIPIEKIYNKTQRSLLGPLIWRM 778
[188][TOP]
>UniRef100_B3GD23 Topoisomerase I (Fragment) n=1 Tax=Laccophilus pictus
RepID=B3GD23_9DYTI
Length = 247
Score = 75.5 bits (184), Expect = 2e-12
Identities = 32/77 (41%), Positives = 56/77 (72%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ L + +K + + +++K++ +++ K++ALGTS++NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKLVHDKKKKSLDRLKEQLKKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKK 229
Query: 288 HEVPIEKIFNQSLLAKF 238
++VPIEKI+N++ KF
Sbjct: 230 YDVPIEKIYNKTQRDKF 246
[189][TOP]
>UniRef100_C1H484 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb01
RepID=C1H484_PARBA
Length = 900
Score = 75.5 bits (184), Expect = 2e-12
Identities = 39/92 (42%), Positives = 61/92 (66%), Gaps = 1/92 (1%)
Frame = -1
Query: 474 PDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWC 295
P+GK ++ E LE ++ + +IE M + KE+ K VALGTS+INY+DPR+TV +
Sbjct: 812 PEGK---GVTVEKLENQLLKLGQRIENMSLQAEDKENNKEVALGTSKINYIDPRLTVVFS 868
Query: 294 KRHEVPIEKIFNQSLLAKFTWAM-DVDPDFRF 202
++ VP+EK F+++L KF WA+ VD ++ F
Sbjct: 869 RKFNVPMEKFFSKTLREKFDWAIKSVDENWEF 900
[190][TOP]
>UniRef100_C1GKM6 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb18
RepID=C1GKM6_PARBD
Length = 825
Score = 75.5 bits (184), Expect = 2e-12
Identities = 39/92 (42%), Positives = 61/92 (66%), Gaps = 1/92 (1%)
Frame = -1
Query: 474 PDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWC 295
P+GK ++ E LE ++ + +IE M + KE+ K VALGTS+INY+DPR+TV +
Sbjct: 737 PEGK---GVTVEKLENQLLKLGQRIENMSLQAEDKENNKEVALGTSKINYIDPRLTVVFS 793
Query: 294 KRHEVPIEKIFNQSLLAKFTWAM-DVDPDFRF 202
++ VP+EK F+++L KF WA+ VD ++ F
Sbjct: 794 RKFNVPMEKFFSKTLREKFDWAIKSVDENWEF 825
[191][TOP]
>UniRef100_C0SEQ3 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb03
RepID=C0SEQ3_PARBP
Length = 905
Score = 75.5 bits (184), Expect = 2e-12
Identities = 39/92 (42%), Positives = 61/92 (66%), Gaps = 1/92 (1%)
Frame = -1
Query: 474 PDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWC 295
P+GK ++ E LE ++ + +IE M + KE+ K VALGTS+INY+DPR+TV +
Sbjct: 817 PEGK---GVTVEKLENQLLKLGQRIENMSLQAEDKENNKEVALGTSKINYIDPRLTVVFS 873
Query: 294 KRHEVPIEKIFNQSLLAKFTWAM-DVDPDFRF 202
++ VP+EK F+++L KF WA+ VD ++ F
Sbjct: 874 RKFNVPMEKFFSKTLREKFDWAIKSVDENWEF 905
[192][TOP]
>UniRef100_Q6IM78 DNA topoisomerase I, mitochondrial n=1 Tax=Rattus norvegicus
RepID=TOP1M_RAT
Length = 593
Score = 75.5 bits (184), Expect = 2e-12
Identities = 39/91 (42%), Positives = 56/91 (61%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K K L + K+ + A++ D KE+ K VALGT+++NYLDPRI++AWCK
Sbjct: 506 DSKSKSFLQKQQRLLKLEEQLARLCTKATD---KEENKQVALGTAKLNYLDPRISIAWCK 562
Query: 291 RHEVPIEKIFNQSLLAKFTWAMD-VDPDFRF 202
R VP+EKI+N++ +F WA + DF F
Sbjct: 563 RFGVPVEKIYNKTQRERFAWAFNQAGEDFEF 593
[193][TOP]
>UniRef100_UPI000069F011 UPI000069F011 related cluster n=1 Tax=Xenopus (Silurana) tropicalis
RepID=UPI000069F011
Length = 503
Score = 75.1 bits (183), Expect = 2e-12
Identities = 35/88 (39%), Positives = 59/88 (67%), Gaps = 1/88 (1%)
Frame = -1
Query: 462 KKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHE 283
+K N E+ ++ + + ++ +M+ +E+ K +AL TS++NYLDPRI+VAWCK+
Sbjct: 416 EKLNKVVESKKRGVQRAEEQLMRMEVQATDREENKQIALSTSKLNYLDPRISVAWCKKWT 475
Query: 282 VPIEKIFNQSLLAKFTWAMDV-DPDFRF 202
V +EKI+N++ KF WA+D+ + DF F
Sbjct: 476 VGLEKIYNKTYRDKFAWAVDMTETDFIF 503
[194][TOP]
>UniRef100_Q9D6H0 Putative uncharacterized protein n=1 Tax=Mus musculus
RepID=Q9D6H0_MOUSE
Length = 295
Score = 75.1 bits (183), Expect = 2e-12
Identities = 39/91 (42%), Positives = 56/91 (61%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K K L + K+ + A++ D KE+ K VALGT+++NYLDPRI++AWCK
Sbjct: 208 DSKPKSFLQKQRRLLKLEEQLARLCAKATD---KEENKQVALGTAKLNYLDPRISIAWCK 264
Query: 291 RHEVPIEKIFNQSLLAKFTWAMD-VDPDFRF 202
R VP+EKI+N++ +F WA + DF F
Sbjct: 265 RFGVPVEKIYNKTQRERFAWAFNQAGEDFEF 295
[195][TOP]
>UniRef100_B7ZNM9 Top1mt protein n=1 Tax=Mus musculus RepID=B7ZNM9_MOUSE
Length = 592
Score = 75.1 bits (183), Expect = 2e-12
Identities = 39/91 (42%), Positives = 56/91 (61%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K K L + K+ + A++ D KE+ K VALGT+++NYLDPRI++AWCK
Sbjct: 505 DSKPKSFLQKQRRLLKLEEQLARLCAKATD---KEENKQVALGTAKLNYLDPRISIAWCK 561
Query: 291 RHEVPIEKIFNQSLLAKFTWAMD-VDPDFRF 202
R VP+EKI+N++ +F WA + DF F
Sbjct: 562 RFGVPVEKIYNKTQRERFAWAFNQAGEDFEF 592
[196][TOP]
>UniRef100_Q59XR0 Likely DNA topoisomerase I n=1 Tax=Candida albicans
RepID=Q59XR0_CANAL
Length = 780
Score = 75.1 bits (183), Expect = 2e-12
Identities = 37/86 (43%), Positives = 58/86 (67%), Gaps = 1/86 (1%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
KN + E L+++I KI + +K KED V+LGTS++NY+DPR+ V + K+ +VP
Sbjct: 695 KNATVEKLKQQIETLENKILNVSIQLKDKEDNSEVSLGTSKMNYIDPRLIVMFSKKFDVP 754
Query: 276 IEKIFNQSLLAKFTWAMD-VDPDFRF 202
IEK+F ++L KF WA++ D ++RF
Sbjct: 755 IEKLFTKTLREKFIWAIESADENWRF 780
[197][TOP]
>UniRef100_Q59WV6 Likely DNA topoisomerase I n=1 Tax=Candida albicans
RepID=Q59WV6_CANAL
Length = 780
Score = 75.1 bits (183), Expect = 2e-12
Identities = 37/86 (43%), Positives = 58/86 (67%), Gaps = 1/86 (1%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
KN + E L+++I KI + +K KED V+LGTS++NY+DPR+ V + K+ +VP
Sbjct: 695 KNATVEKLKQQIETLENKILNVSIQLKDKEDNSEVSLGTSKMNYIDPRLIVMFSKKFDVP 754
Query: 276 IEKIFNQSLLAKFTWAMD-VDPDFRF 202
IEK+F ++L KF WA++ D ++RF
Sbjct: 755 IEKLFTKTLREKFIWAIESADENWRF 780
[198][TOP]
>UniRef100_Q8R4U6 DNA topoisomerase I, mitochondrial n=1 Tax=Mus musculus
RepID=TOP1M_MOUSE
Length = 593
Score = 75.1 bits (183), Expect = 2e-12
Identities = 39/91 (42%), Positives = 56/91 (61%), Gaps = 1/91 (1%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K K L + K+ + A++ D KE+ K VALGT+++NYLDPRI++AWCK
Sbjct: 506 DSKPKSFLQKQRRLLKLEEQLARLCAKATD---KEENKQVALGTAKLNYLDPRISIAWCK 562
Query: 291 RHEVPIEKIFNQSLLAKFTWAMD-VDPDFRF 202
R VP+EKI+N++ +F WA + DF F
Sbjct: 563 RFGVPVEKIYNKTQRERFAWAFNQAGEDFEF 593
[199][TOP]
>UniRef100_A5E508 DNA topoisomerase I n=1 Tax=Lodderomyces elongisporus
RepID=A5E508_LODEL
Length = 849
Score = 74.7 bits (182), Expect = 3e-12
Identities = 36/86 (41%), Positives = 56/86 (65%), Gaps = 1/86 (1%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K + E L+ ++ +I +K KED V+LGTS++NY+DPR+TV + K+ +VP
Sbjct: 764 KGATVEKLKTQVENMENRIVSTTLQLKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFDVP 823
Query: 276 IEKIFNQSLLAKFTWAMD-VDPDFRF 202
IEK+F ++L KF WA++ D D+RF
Sbjct: 824 IEKLFTKTLREKFKWAIESTDKDWRF 849
[200][TOP]
>UniRef100_Q00313 DNA topoisomerase 1 n=1 Tax=Candida albicans RepID=TOP1_CANAL
Length = 778
Score = 73.9 bits (180), Expect = 5e-12
Identities = 36/86 (41%), Positives = 58/86 (67%), Gaps = 1/86 (1%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
KN + E L+++I +I + +K KED V+LGTS++NY+DPR+ V + K+ +VP
Sbjct: 693 KNATVEKLKQQIETLENRILNVSIQLKDKEDNSEVSLGTSKMNYIDPRLIVMFSKKFDVP 752
Query: 276 IEKIFNQSLLAKFTWAMD-VDPDFRF 202
IEK+F ++L KF WA++ D ++RF
Sbjct: 753 IEKLFTKTLREKFIWAIESADENWRF 778
[201][TOP]
>UniRef100_B3GD22 Topoisomerase I (Fragment) n=1 Tax=Chauliognathus opacus
RepID=B3GD22_9COLE
Length = 247
Score = 73.6 bits (179), Expect = 7e-12
Identities = 33/77 (42%), Positives = 53/77 (68%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ E K + + ++ K++ +++ KT+ALGTS++NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKTVYEKKRKLLERLKEQLTKLEIQETDRDENKTIALGTSKLNYLDPRISVAWCKK 229
Query: 288 HEVPIEKIFNQSLLAKF 238
++VPIEKI+N++ KF
Sbjct: 230 NDVPIEKIYNKTQRDKF 246
[202][TOP]
>UniRef100_C5M985 DNA topoisomerase I n=1 Tax=Candida tropicalis MYA-3404
RepID=C5M985_CANTT
Length = 777
Score = 73.6 bits (179), Expect = 7e-12
Identities = 37/86 (43%), Positives = 57/86 (66%), Gaps = 1/86 (1%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
KN + E L+ +I +I +K KED V+LGTS++NY+DPR+TV + K+ +VP
Sbjct: 692 KNATVEKLKGQIETLENRILTTSFQLKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFDVP 751
Query: 276 IEKIFNQSLLAKFTWAMD-VDPDFRF 202
IEK+F ++L KF WA++ D ++RF
Sbjct: 752 IEKLFTKTLRDKFKWAIESTDENWRF 777
[203][TOP]
>UniRef100_B3GD37 Topoisomerase I (Fragment) n=1 Tax=Bembidion mandibulare
RepID=B3GD37_9CARA
Length = 247
Score = 73.2 bits (178), Expect = 9e-12
Identities = 36/76 (47%), Positives = 55/76 (72%)
Frame = -1
Query: 465 KKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRH 286
KKKK L +++ + K+E M+ D +++ K +ALGTS++NYLDPRI+VAWCK++
Sbjct: 180 KKKKTL------ERLKEQLMKLEVMETD---RDENKAIALGTSKLNYLDPRISVAWCKKY 230
Query: 285 EVPIEKIFNQSLLAKF 238
+VPIEKI+N++ KF
Sbjct: 231 DVPIEKIYNKTQRDKF 246
[204][TOP]
>UniRef100_C4R3Z3 Topoisomerase I n=1 Tax=Pichia pastoris GS115 RepID=C4R3Z3_PICPG
Length = 763
Score = 72.8 bits (177), Expect = 1e-11
Identities = 32/80 (40%), Positives = 54/80 (67%)
Frame = -1
Query: 462 KKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHE 283
K ++ E LE ++ + +I ++ KED VALGTS++NY+DPR+T + K+++
Sbjct: 676 KSVTVTVEKLESQVEKLEQRIRNATLLLQDKEDNSQVALGTSKLNYIDPRLTAMFSKKYD 735
Query: 282 VPIEKIFNQSLLAKFTWAMD 223
VPIEK+F+++L KF WA++
Sbjct: 736 VPIEKLFSKTLREKFAWAIE 755
[205][TOP]
>UniRef100_A4R0K7 Putative uncharacterized protein n=1 Tax=Magnaporthe grisea
RepID=A4R0K7_MAGGR
Length = 906
Score = 72.8 bits (177), Expect = 1e-11
Identities = 32/77 (41%), Positives = 52/77 (67%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
+ ++ E LE+++ + +I M+ ++ K VALGTS+INY+DPR+TV +C + VP
Sbjct: 819 RGVTVEKLEQQVKKLDERIRTMELQAADRDGNKEVALGTSKINYIDPRLTVVFCNKMNVP 878
Query: 276 IEKIFNQSLLAKFTWAM 226
IEK F+++L KF WA+
Sbjct: 879 IEKFFSKTLREKFNWAI 895
[206][TOP]
>UniRef100_UPI00003BE191 hypothetical protein DEHA0F10945g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE191
Length = 789
Score = 72.4 bits (176), Expect = 1e-11
Identities = 35/87 (40%), Positives = 58/87 (66%), Gaps = 1/87 (1%)
Frame = -1
Query: 459 KKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEV 280
KK+++ E L+ ++ +I +K KED V+LGTS++NY+DPR+TV + K+ V
Sbjct: 703 KKSVTVEKLKSQVDTLTNRILNTTFQLKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFNV 762
Query: 279 PIEKIFNQSLLAKFTWAMD-VDPDFRF 202
PIEK+F ++L KF WA++ D +++F
Sbjct: 763 PIEKLFTKTLRDKFNWAIESADENWKF 789
[207][TOP]
>UniRef100_B3GD30 Topoisomerase I (Fragment) n=1 Tax=Metrius contractus
RepID=B3GD30_METCO
Length = 281
Score = 72.4 bits (176), Expect = 1e-11
Identities = 31/77 (40%), Positives = 55/77 (71%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ + + +K + + ++ K++ +++ K++ALGTS++NYLDPRI+VAWCK+
Sbjct: 204 GSVKEKVVYDKKKKALERLRDQLMKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKK 263
Query: 288 HEVPIEKIFNQSLLAKF 238
++VPIEKI+N++ KF
Sbjct: 264 YDVPIEKIYNKTQRDKF 280
[208][TOP]
>UniRef100_Q6BLX2 DEHA2F09988p n=1 Tax=Debaryomyces hansenii RepID=Q6BLX2_DEBHA
Length = 789
Score = 72.4 bits (176), Expect = 1e-11
Identities = 35/87 (40%), Positives = 58/87 (66%), Gaps = 1/87 (1%)
Frame = -1
Query: 459 KKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEV 280
KK+++ E L+ ++ +I +K KED V+LGTS++NY+DPR+TV + K+ V
Sbjct: 703 KKSVTVEKLKSQVDTLTNRILNTTFQLKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFNV 762
Query: 279 PIEKIFNQSLLAKFTWAMD-VDPDFRF 202
PIEK+F ++L KF WA++ D +++F
Sbjct: 763 PIEKLFTKTLRDKFNWAIESADENWKF 789
[209][TOP]
>UniRef100_B3GD42 Topoisomerase I (Fragment) n=1 Tax=Bembidion inaequale
RepID=B3GD42_9CARA
Length = 247
Score = 72.0 bits (175), Expect = 2e-11
Identities = 31/77 (40%), Positives = 55/77 (71%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ + + +K + + ++ K++ +++ K++ALGTS++NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVYDKKKKMLERLKEQLIKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKK 229
Query: 288 HEVPIEKIFNQSLLAKF 238
++VPIEKI+N++ KF
Sbjct: 230 YDVPIEKIYNKTQRDKF 246
[210][TOP]
>UniRef100_B3GD39 Topoisomerase I (Fragment) n=2 Tax=Pseudoperyphus
RepID=B3GD39_9CARA
Length = 247
Score = 72.0 bits (175), Expect = 2e-11
Identities = 31/77 (40%), Positives = 55/77 (71%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ + + +K + + ++ K++ +++ K++ALGTS++NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVYDKKKKMLERLKEQLIKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKK 229
Query: 288 HEVPIEKIFNQSLLAKF 238
++VPIEKI+N++ KF
Sbjct: 230 YDVPIEKIYNKTQRDKF 246
[211][TOP]
>UniRef100_B3GD38 Topoisomerase I (Fragment) n=1 Tax=Bembidion concolor
RepID=B3GD38_9CARA
Length = 247
Score = 72.0 bits (175), Expect = 2e-11
Identities = 31/77 (40%), Positives = 55/77 (71%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ + + +K + + ++ K++ +++ K++ALGTS++NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVYDKKKKMLERLKEQLIKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKK 229
Query: 288 HEVPIEKIFNQSLLAKF 238
++VPIEKI+N++ KF
Sbjct: 230 YDVPIEKIYNKTQRDKF 246
[212][TOP]
>UniRef100_B3GD36 Topoisomerase I (Fragment) n=1 Tax=Bembidion rapidum
RepID=B3GD36_9CARA
Length = 247
Score = 72.0 bits (175), Expect = 2e-11
Identities = 31/77 (40%), Positives = 54/77 (70%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ + + +K + + ++ K++ +++ K +ALGTS++NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVYDKKKKMLERLKEQLVKLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKK 229
Query: 288 HEVPIEKIFNQSLLAKF 238
++VPIEKI+N++ KF
Sbjct: 230 YDVPIEKIYNKTQRDKF 246
[213][TOP]
>UniRef100_B3GD34 Topoisomerase I (Fragment) n=1 Tax=Bembidion umbratum
RepID=B3GD34_9CARA
Length = 247
Score = 72.0 bits (175), Expect = 2e-11
Identities = 31/77 (40%), Positives = 54/77 (70%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ + + +K + + ++ K++ +++ K +ALGTS++NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVYDKKKKMLERLKEQLIKLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKK 229
Query: 288 HEVPIEKIFNQSLLAKF 238
++VPIEKI+N++ KF
Sbjct: 230 YDVPIEKIYNKTXRDKF 246
[214][TOP]
>UniRef100_B3GD29 Topoisomerase I (Fragment) n=1 Tax=Scaphinotus petersi
RepID=B3GD29_9CARA
Length = 247
Score = 72.0 bits (175), Expect = 2e-11
Identities = 31/77 (40%), Positives = 55/77 (71%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ + + +K + + ++ K++ +++ K++ALGTS++NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVYDKKKKTLERLKDQLMKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKK 229
Query: 288 HEVPIEKIFNQSLLAKF 238
++VPIEKI+N++ KF
Sbjct: 230 YDVPIEKIYNKAQRDKF 246
[215][TOP]
>UniRef100_A7EXF7 Putative uncharacterized protein n=1 Tax=Sclerotinia sclerotiorum
1980 UF-70 RepID=A7EXF7_SCLS1
Length = 911
Score = 72.0 bits (175), Expect = 2e-11
Identities = 35/78 (44%), Positives = 51/78 (65%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K S E E I++ +I M + +E K VALGTS+INY+DPR+TV + ++ +VP
Sbjct: 824 KGSSVEKFEANITKIDERIANMLLKREDREGNKEVALGTSKINYIDPRLTVVFSQKFDVP 883
Query: 276 IEKIFNQSLLAKFTWAMD 223
IEK F+++L KF WA+D
Sbjct: 884 IEKFFSKTLREKFAWAID 901
[216][TOP]
>UniRef100_UPI000151AE34 hypothetical protein PGUG_04275 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151AE34
Length = 754
Score = 71.6 bits (174), Expect = 3e-11
Identities = 34/87 (39%), Positives = 57/87 (65%), Gaps = 1/87 (1%)
Frame = -1
Query: 459 KKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEV 280
K + E L+ ++ + +I ++ KED V+LGTS++NY+DPR+TV + K+ +V
Sbjct: 668 KSTTTVEKLKAQVEKLDGRIVNTTFQLQDKEDNSEVSLGTSKLNYIDPRLTVMFSKKFDV 727
Query: 279 PIEKIFNQSLLAKFTWAMD-VDPDFRF 202
PIEK+F ++L KF WA++ D ++RF
Sbjct: 728 PIEKLFTKTLRDKFKWAIESADENWRF 754
[217][TOP]
>UniRef100_UPI00016E5F97 UPI00016E5F97 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F97
Length = 790
Score = 71.6 bits (174), Expect = 3e-11
Identities = 34/75 (45%), Positives = 51/75 (68%)
Frame = -1
Query: 477 SPDGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAW 298
S D K KK + E K + + ++ K+Q +E+ K +ALGTS++NYLDPRI+VAW
Sbjct: 715 SHDDKSKKAV--EVKRKAVQRIEEQLMKLQVQATDREENKQIALGTSKLNYLDPRISVAW 772
Query: 297 CKRHEVPIEKIFNQS 253
CK+ +PIEKI+N++
Sbjct: 773 CKKFGIPIEKIYNKT 787
[218][TOP]
>UniRef100_B3GD43 Topoisomerase I (Fragment) n=1 Tax=Bembidion chalceum
RepID=B3GD43_9CARA
Length = 247
Score = 71.6 bits (174), Expect = 3e-11
Identities = 31/77 (40%), Positives = 54/77 (70%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ + + +K + + ++ K++ +++ K +ALGTS++NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVYDKKKKMLERLKEQLIKLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKK 229
Query: 288 HEVPIEKIFNQSLLAKF 238
++VPIEKI+N++ KF
Sbjct: 230 YDVPIEKIYNKTQRDKF 246
[219][TOP]
>UniRef100_B3GD41 Topoisomerase I (Fragment) n=1 Tax=Bembidion inaequale
RepID=B3GD41_9CARA
Length = 247
Score = 71.6 bits (174), Expect = 3e-11
Identities = 35/76 (46%), Positives = 56/76 (73%)
Frame = -1
Query: 465 KKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRH 286
KKKK L +++ + K+E ++ D +++ K++ALGTS++NYLDPRI+VAWCK++
Sbjct: 180 KKKKML------ERLKEQLIKLEVLETD---RDENKSIALGTSKLNYLDPRISVAWCKKY 230
Query: 285 EVPIEKIFNQSLLAKF 238
+VPIEKI+N++ KF
Sbjct: 231 DVPIEKIYNKTQRDKF 246
[220][TOP]
>UniRef100_B3GD35 Topoisomerase I (Fragment) n=1 Tax=Bembidion plagiatum
RepID=B3GD35_9CARA
Length = 247
Score = 71.6 bits (174), Expect = 3e-11
Identities = 31/77 (40%), Positives = 54/77 (70%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ + + +K + + ++ K++ +++ K +ALGTS++NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVYDKKKKMLERLKEQLIKLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKK 229
Query: 288 HEVPIEKIFNQSLLAKF 238
++VPIEKI+N++ KF
Sbjct: 230 YDVPIEKIYNKTQRDKF 246
[221][TOP]
>UniRef100_B3GD33 Topoisomerase I (Fragment) n=1 Tax=Bembidion transversale
RepID=B3GD33_9CARA
Length = 247
Score = 71.6 bits (174), Expect = 3e-11
Identities = 31/77 (40%), Positives = 54/77 (70%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ + + +K + + ++ K++ +++ K +ALGTS++NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVYDKKKKMLERLKEQLIKLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKK 229
Query: 288 HEVPIEKIFNQSLLAKF 238
++VPIEKI+N++ KF
Sbjct: 230 YDVPIEKIYNKTQRHKF 246
[222][TOP]
>UniRef100_B3GD32 Topoisomerase I (Fragment) n=1 Tax=Asaphidion yukonense
RepID=B3GD32_9CARA
Length = 247
Score = 71.6 bits (174), Expect = 3e-11
Identities = 36/76 (47%), Positives = 54/76 (71%)
Frame = -1
Query: 465 KKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRH 286
KKKK L +K+ + K+E + D +++ K +ALGTS++NYLDPRI+VAWCK++
Sbjct: 180 KKKKML------EKLKEQLIKLEVQETD---RDENKAIALGTSKLNYLDPRISVAWCKKY 230
Query: 285 EVPIEKIFNQSLLAKF 238
+VPIEKI+N++ KF
Sbjct: 231 DVPIEKIYNKTQRDKF 246
[223][TOP]
>UniRef100_B3GD28 Topoisomerase I (Fragment) n=1 Tax=Calosoma scrutator
RepID=B3GD28_CALSB
Length = 281
Score = 71.6 bits (174), Expect = 3e-11
Identities = 32/77 (41%), Positives = 54/77 (70%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ + + +K + + ++ K++ K++ K++ALGTS++NYLDPRI+VAWCK+
Sbjct: 204 GSVKEKVVYDKKKKALEKLKDQLVKLEVQETDKDENKSIALGTSKLNYLDPRISVAWCKK 263
Query: 288 HEVPIEKIFNQSLLAKF 238
+ VPIEKI+N++ KF
Sbjct: 264 YGVPIEKIYNKTQRDKF 280
[224][TOP]
>UniRef100_B3GD21 Topoisomerase I (Fragment) n=1 Tax=Prolixocupes lobiceps
RepID=B3GD21_9COLE
Length = 229
Score = 71.6 bits (174), Expect = 3e-11
Identities = 31/77 (40%), Positives = 54/77 (70%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ + + +K + + ++ K++ +++ K++ALGTS++NYLDPRITVAWCK+
Sbjct: 152 GSVKEKVVYDKKKKHLERLREQLVKLEVAETDRDENKSIALGTSKLNYLDPRITVAWCKK 211
Query: 288 HEVPIEKIFNQSLLAKF 238
+ VPIEK++N++ KF
Sbjct: 212 YGVPIEKVYNKTQRDKF 228
[225][TOP]
>UniRef100_A5DLX4 Putative uncharacterized protein n=1 Tax=Pichia guilliermondii
RepID=A5DLX4_PICGU
Length = 754
Score = 71.6 bits (174), Expect = 3e-11
Identities = 34/87 (39%), Positives = 57/87 (65%), Gaps = 1/87 (1%)
Frame = -1
Query: 459 KKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEV 280
K + E L+ ++ + +I ++ KED V+LGTS++NY+DPR+TV + K+ +V
Sbjct: 668 KSTTTVEKLKAQVEKLDGRIVNTTFQLQDKEDNSEVSLGTSKLNYIDPRLTVMFSKKFDV 727
Query: 279 PIEKIFNQSLLAKFTWAMD-VDPDFRF 202
PIEK+F ++L KF WA++ D ++RF
Sbjct: 728 PIEKLFTKTLRDKFKWAIESADENWRF 754
[226][TOP]
>UniRef100_Q70HS8 DNA topoisomerase I subunit B (Fragment) n=1 Tax=Leishmania
panamensis RepID=Q70HS8_9TRYP
Length = 269
Score = 71.2 bits (173), Expect = 3e-11
Identities = 29/71 (40%), Positives = 49/71 (69%)
Frame = -1
Query: 429 KKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIFNQSL 250
K + + ++ + + ++ K+D K V+LGTS+INY+DPRI +W K +VPI K+F+ ++
Sbjct: 195 KALVRYRERLNREENVIRIKDDNKAVSLGTSKINYIDPRIVCSWAKAQDVPISKVFSATI 254
Query: 249 LAKFTWAMDVD 217
L KF WAM+ +
Sbjct: 255 LKKFPWAMNAE 265
[227][TOP]
>UniRef100_Q4YYG2 Topoisomerase I, putative (Fragment) n=1 Tax=Plasmodium berghei
RepID=Q4YYG2_PLABE
Length = 805
Score = 71.2 bits (173), Expect = 3e-11
Identities = 31/62 (50%), Positives = 47/62 (75%)
Frame = -1
Query: 465 KKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRH 286
K K+N+ E+ +KK+ K+E ++ MK ++D KT+ALGTS+INY+DPRITVA+CK+
Sbjct: 744 KVKENMKEESCKKKLIALIKKVELLENQMKVRDDNKTIALGTSKINYMDPRITVAFCKQF 803
Query: 285 EV 280
E+
Sbjct: 804 EI 805
[228][TOP]
>UniRef100_P41512 DNA topoisomerase 1 n=1 Tax=Xenopus laevis RepID=TOP1_XENLA
Length = 829
Score = 71.2 bits (173), Expect = 3e-11
Identities = 33/73 (45%), Positives = 53/73 (72%)
Frame = -1
Query: 471 DGKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCK 292
D K KK + S+ +K + + ++ K++ +E+ K +ALGTS++NYLDPRI+VAWCK
Sbjct: 733 DEKTKKLVESK--KKAVQRIEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCK 790
Query: 291 RHEVPIEKIFNQS 253
++ VPIEKI+N++
Sbjct: 791 KYGVPIEKIYNKT 803
[229][TOP]
>UniRef100_Q38EP5 DNA topoisomerase type IB small subunit n=1 Tax=Trypanosoma brucei
RepID=Q38EP5_9TRYP
Length = 273
Score = 70.9 bits (172), Expect = 4e-11
Identities = 31/78 (39%), Positives = 52/78 (66%)
Frame = -1
Query: 435 LEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIFNQ 256
+E +I + +++ ++ +K K+D KTV+LGTS++NY+DPRI +W + VPI ++F+
Sbjct: 197 IEAEIGKHEKRLKDVENMLKMKQDNKTVSLGTSKVNYIDPRIVCSWANENNVPISRLFSA 256
Query: 255 SLLAKFTWAMDVDPDFRF 202
+L KF WA+ DF F
Sbjct: 257 TLQKKFPWALKA-RDFTF 273
[230][TOP]
>UniRef100_C9ZXZ7 DNA topoisomerase type IB small subunit, putative n=2
Tax=Trypanosoma brucei RepID=C9ZXZ7_TRYBG
Length = 273
Score = 70.9 bits (172), Expect = 4e-11
Identities = 31/78 (39%), Positives = 52/78 (66%)
Frame = -1
Query: 435 LEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIFNQ 256
+E +I + +++ ++ +K K+D KTV+LGTS++NY+DPRI +W + VPI ++F+
Sbjct: 197 IEAEIGKHEKRLKDVENMLKMKQDNKTVSLGTSKVNYIDPRIVCSWANENNVPISRLFSA 256
Query: 255 SLLAKFTWAMDVDPDFRF 202
+L KF WA+ DF F
Sbjct: 257 TLQKKFPWALKA-RDFTF 273
[231][TOP]
>UniRef100_A4H3S7 DNA topoisomerase type IB small subunit n=1 Tax=Leishmania
braziliensis RepID=A4H3S7_LEIBR
Length = 269
Score = 70.9 bits (172), Expect = 4e-11
Identities = 29/71 (40%), Positives = 48/71 (67%)
Frame = -1
Query: 429 KKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIFNQSL 250
K + + ++ + + ++ K+D K V+LGTS+INY+DPRI +W K +VPI K+F+ ++
Sbjct: 195 KALVRYRERLNREENVIRIKDDNKAVSLGTSKINYIDPRIVCSWAKAQDVPISKVFSATI 254
Query: 249 LAKFTWAMDVD 217
L KF WAM +
Sbjct: 255 LKKFPWAMSAE 265
[232][TOP]
>UniRef100_B2AY06 Predicted CDS Pa_1_9460 n=1 Tax=Podospora anserina RepID=B2AY06_PODAN
Length = 904
Score = 70.9 bits (172), Expect = 4e-11
Identities = 34/78 (43%), Positives = 52/78 (66%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K + E LE +S+ +I+ ++ +E K VALGTS+INY+DPR+TV + K+ VP
Sbjct: 817 KGPAVEKLEAAVSKFDDRIKTLELQCADREGNKEVALGTSKINYIDPRLTVVFAKKFNVP 876
Query: 276 IEKIFNQSLLAKFTWAMD 223
IEK F+++L KF WA++
Sbjct: 877 IEKFFSKTLRDKFKWAIE 894
[233][TOP]
>UniRef100_A6S3Q9 Putative uncharacterized protein n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6S3Q9_BOTFB
Length = 912
Score = 70.5 bits (171), Expect = 6e-11
Identities = 34/78 (43%), Positives = 51/78 (65%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K S + E I++ +I M + +E K VALGTS+INY+DPR+TV + ++ +VP
Sbjct: 825 KGPSVDKFEANITKIDERIANMLLKREDREGNKEVALGTSKINYIDPRLTVVFSQKFDVP 884
Query: 276 IEKIFNQSLLAKFTWAMD 223
IEK F+++L KF WA+D
Sbjct: 885 IEKFFSKTLREKFAWAID 902
[234][TOP]
>UniRef100_Q95Z89 Possible DNA topoisomerase I-related protein n=1 Tax=Leishmania
major RepID=Q95Z89_LEIMA
Length = 262
Score = 69.7 bits (169), Expect = 1e-10
Identities = 29/71 (40%), Positives = 48/71 (67%)
Frame = -1
Query: 429 KKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIFNQSL 250
K + + ++ + + ++ K+D K V+LGTS+INY+DPRI +W K +VPI KIF+ ++
Sbjct: 188 KALERYRERLNREENIIRIKDDNKAVSLGTSKINYIDPRIICSWAKAQDVPINKIFSATI 247
Query: 249 LAKFTWAMDVD 217
KF WAM+ +
Sbjct: 248 QKKFPWAMNAE 258
[235][TOP]
>UniRef100_Q8WQM6 DNA topoisomerase I-like protein n=1 Tax=Leishmania donovani
RepID=Q8WQM6_LEIDO
Length = 262
Score = 69.7 bits (169), Expect = 1e-10
Identities = 29/71 (40%), Positives = 48/71 (67%)
Frame = -1
Query: 429 KKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIFNQSL 250
K + + ++ + + ++ K+D K V+LGTS+INY+DPRI +W K +VPI KIF+ ++
Sbjct: 188 KALERYRERLNREENIIRIKDDNKAVSLGTSKINYIDPRIICSWAKAQDVPINKIFSATI 247
Query: 249 LAKFTWAMDVD 217
KF WAM+ +
Sbjct: 248 QKKFPWAMNAE 258
[236][TOP]
>UniRef100_A4HS02 DNA topoisomerase type IB small subunit n=1 Tax=Leishmania infantum
RepID=A4HS02_LEIIN
Length = 262
Score = 69.7 bits (169), Expect = 1e-10
Identities = 29/71 (40%), Positives = 48/71 (67%)
Frame = -1
Query: 429 KKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIFNQSL 250
K + + ++ + + ++ K+D K V+LGTS+INY+DPRI +W K +VPI KIF+ ++
Sbjct: 188 KALERYRERLNREENIIRIKDDNKAVSLGTSKINYIDPRIICSWAKAQDVPINKIFSATI 247
Query: 249 LAKFTWAMDVD 217
KF WAM+ +
Sbjct: 248 QKKFPWAMNAE 258
[237][TOP]
>UniRef100_Q7S0F7 DNA topoisomerase I n=1 Tax=Neurospora crassa RepID=Q7S0F7_NEUCR
Length = 874
Score = 68.9 bits (167), Expect = 2e-10
Identities = 33/78 (42%), Positives = 50/78 (64%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K S E LE + + +I+ ++ +E K VALGTS+INY+DPR+TV + + VP
Sbjct: 787 KGPSVEKLEAALEKLDQRIKNLELQSADREGNKEVALGTSKINYIDPRLTVVFSAKFNVP 846
Query: 276 IEKIFNQSLLAKFTWAMD 223
IEK F+++L KF WA++
Sbjct: 847 IEKFFSKTLREKFKWAIE 864
[238][TOP]
>UniRef100_Q5RL92 Type IB topoisomerase small subunit n=1 Tax=Trypanosoma cruzi
RepID=Q5RL92_TRYCR
Length = 271
Score = 67.8 bits (164), Expect = 4e-10
Identities = 28/63 (44%), Positives = 44/63 (69%)
Frame = -1
Query: 405 KIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIFNQSLLAKFTWAM 226
++ + + ++ K+D K V+LGTS++NY+DPRI +W K + VPI KIF+ +L KF WAM
Sbjct: 205 RLNREENMIRIKDDNKAVSLGTSKVNYIDPRIVCSWAKEYNVPIGKIFSATLQKKFPWAM 264
Query: 225 DVD 217
+
Sbjct: 265 GAE 267
[239][TOP]
>UniRef100_Q4DUD0 DNA topoisomerase type IB small subunit, putative n=1
Tax=Trypanosoma cruzi RepID=Q4DUD0_TRYCR
Length = 272
Score = 67.8 bits (164), Expect = 4e-10
Identities = 28/63 (44%), Positives = 44/63 (69%)
Frame = -1
Query: 405 KIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIFNQSLLAKFTWAM 226
++ + + ++ K+D K V+LGTS++NY+DPRI +W K + VPI KIF+ +L KF WAM
Sbjct: 206 RLNREENMIRIKDDNKAVSLGTSKVNYIDPRIVCSWAKEYNVPIGKIFSATLQKKFPWAM 265
Query: 225 DVD 217
+
Sbjct: 266 GAE 268
[240][TOP]
>UniRef100_Q2HDT9 Putative uncharacterized protein n=1 Tax=Chaetomium globosum
RepID=Q2HDT9_CHAGB
Length = 907
Score = 67.0 bits (162), Expect = 6e-10
Identities = 32/77 (41%), Positives = 48/77 (62%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
K S E L + + +I ++ +E K VALGTS+INY+DPR+TV + + +VP
Sbjct: 820 KGPSVEKLTTAVEKLDERIRTLEMQSADREGNKEVALGTSKINYIDPRLTVVFSNKFQVP 879
Query: 276 IEKIFNQSLLAKFTWAM 226
IEK F+++L KF WA+
Sbjct: 880 IEKFFSKTLRDKFNWAI 896
[241][TOP]
>UniRef100_UPI000023DEFB hypothetical protein FG06874.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023DEFB
Length = 910
Score = 66.2 bits (160), Expect = 1e-09
Identities = 35/97 (36%), Positives = 57/97 (58%), Gaps = 12/97 (12%)
Frame = -1
Query: 480 KSPDGKKKKNLSSEALE------------KKISQTHAKIEKMQRDMKTKEDLKTVALGTS 337
K + K KK S+ +E K + + +I+ ++ + ++ K VALGTS
Sbjct: 803 KEMEAKFKKENKSKKVEAEGRGATVDKFLKAVDKFDERIKTLELQAQDRDGNKEVALGTS 862
Query: 336 QINYLDPRITVAWCKRHEVPIEKIFNQSLLAKFTWAM 226
+INY+DPR+TV + K+ +VPIEK F+++L KF WA+
Sbjct: 863 KINYIDPRLTVVFSKKFDVPIEKFFSKTLRDKFRWAI 899
[242][TOP]
>UniRef100_C7YQG7 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YQG7_NECH7
Length = 919
Score = 66.2 bits (160), Expect = 1e-09
Identities = 29/68 (42%), Positives = 48/68 (70%)
Frame = -1
Query: 429 KKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIFNQSL 250
K I + +++ ++ + ++ K VALGTS+INY+DPR+TV + K+ +VPIEK F+++L
Sbjct: 841 KAIEKLDERVKVLETQAEDRDGNKEVALGTSKINYIDPRLTVVFSKKFDVPIEKFFSKTL 900
Query: 249 LAKFTWAM 226
KF WA+
Sbjct: 901 RDKFRWAI 908
[243][TOP]
>UniRef100_C4PFJ5 Topoisomerase I n=1 Tax=Fusarium culmorum RepID=C4PFJ5_FUSCU
Length = 909
Score = 66.2 bits (160), Expect = 1e-09
Identities = 35/97 (36%), Positives = 57/97 (58%), Gaps = 12/97 (12%)
Frame = -1
Query: 480 KSPDGKKKKNLSSEALE------------KKISQTHAKIEKMQRDMKTKEDLKTVALGTS 337
K + K KK S+ +E K + + +I+ ++ + ++ K VALGTS
Sbjct: 802 KEMEAKFKKENKSKKVEAEGRGATVDKFLKAVDKFDERIKTLELQAQDRDGNKEVALGTS 861
Query: 336 QINYLDPRITVAWCKRHEVPIEKIFNQSLLAKFTWAM 226
+INY+DPR+TV + K+ +VPIEK F+++L KF WA+
Sbjct: 862 KINYIDPRLTVVFSKKFDVPIEKFFSKTLRDKFRWAI 898
[244][TOP]
>UniRef100_A9V5T5 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9V5T5_MONBE
Length = 2575
Score = 65.9 bits (159), Expect = 1e-09
Identities = 27/58 (46%), Positives = 42/58 (72%)
Frame = -1
Query: 441 EALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEK 268
+ L++K+ + ++ K Q KE+ K +AL TS++NYLDPRI+VAWCK H+VP++K
Sbjct: 2334 DVLKRKVDRLEERLHKKQIAKVDKEENKCIALSTSKLNYLDPRISVAWCKTHDVPVDK 2391
[245][TOP]
>UniRef100_C9SIQ6 DNA topoisomerase n=1 Tax=Verticillium albo-atrum VaMs.102
RepID=C9SIQ6_9PEZI
Length = 891
Score = 64.3 bits (155), Expect = 4e-09
Identities = 32/74 (43%), Positives = 50/74 (67%), Gaps = 1/74 (1%)
Frame = -1
Query: 429 KKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVPIEKIFNQSL 250
KKI + +E +D ++ K VALGTS++NY+DPR+TV + ++ +VPIEK F++++
Sbjct: 817 KKIEERAKNLELQAQD---RDGNKEVALGTSKLNYIDPRLTVVFSRKFDVPIEKFFSKTM 873
Query: 249 LAKFTWAM-DVDPD 211
KF WA+ VD D
Sbjct: 874 REKFNWAIQSVDDD 887
[246][TOP]
>UniRef100_B3GD25 Topoisomerase I (Fragment) n=1 Tax=Amphizoa lecontei
RepID=B3GD25_AMPLE
Length = 268
Score = 62.4 bits (150), Expect = 2e-08
Identities = 27/65 (41%), Positives = 46/65 (70%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ + + +K + + ++ K++ K++ K++ALGTS++NYLDPRI+VAWCK+
Sbjct: 204 GSVKEKVVLDKKKKGLERLKDQLVKLEVQETDKDENKSIALGTSKLNYLDPRISVAWCKK 263
Query: 288 HEVPI 274
+EVPI
Sbjct: 264 YEVPI 268
[247][TOP]
>UniRef100_B3GD24 Topoisomerase I (Fragment) n=1 Tax=Copelatus distinctus
RepID=B3GD24_9DYTI
Length = 234
Score = 62.0 bits (149), Expect = 2e-08
Identities = 25/65 (38%), Positives = 47/65 (72%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ + + +K + + +++K++ +++ K++ALGTS++NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVHDKKKKALERLKDQLKKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKK 229
Query: 288 HEVPI 274
++VPI
Sbjct: 230 YDVPI 234
[248][TOP]
>UniRef100_B3GD26 Topoisomerase I (Fragment) n=1 Tax=Dineutes sublineatus
RepID=B3GD26_9COLE
Length = 234
Score = 61.6 bits (148), Expect = 3e-08
Identities = 24/65 (36%), Positives = 48/65 (73%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ + ++ +K++ + ++ +++ +++ K++ALGTS++NYLDPRI+VAWCK+
Sbjct: 170 GSVKERVVADKKKKQLDRLRDQLVRLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKK 229
Query: 288 HEVPI 274
++VPI
Sbjct: 230 YDVPI 234
[249][TOP]
>UniRef100_C3ZV88 Putative uncharacterized protein (Fragment) n=1 Tax=Branchiostoma
floridae RepID=C3ZV88_BRAFL
Length = 299
Score = 61.2 bits (147), Expect = 3e-08
Identities = 30/77 (38%), Positives = 50/77 (64%)
Frame = -1
Query: 456 KNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKRHEVP 277
+ + E +K++ + ++ K++ KE+ K +ALGTS++NYLDPRI+VA K H
Sbjct: 226 RQMMLERKKKQMERLEEQLMKLEVQATDKEENKEIALGTSKLNYLDPRISVACGKSH--- 282
Query: 276 IEKIFNQSLLAKFTWAM 226
+EKI+N++ KF WA+
Sbjct: 283 VEKIYNKTQRDKFAWAL 299
[250][TOP]
>UniRef100_B3GD20 Topoisomerase I (Fragment) n=1 Tax=Sialis sp. ALW-2008
RepID=B3GD20_9NEOP
Length = 234
Score = 61.2 bits (147), Expect = 3e-08
Identities = 25/65 (38%), Positives = 46/65 (70%)
Frame = -1
Query: 468 GKKKKNLSSEALEKKISQTHAKIEKMQRDMKTKEDLKTVALGTSQINYLDPRITVAWCKR 289
G K+ + + +K + + ++ K++ +++ K++ALGTS++NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVHDKKKKALERLRDQLMKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKK 229
Query: 288 HEVPI 274
++VPI
Sbjct: 230 YDVPI 234