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[1][TOP]
>UniRef100_UPI0001985140 PREDICTED: similar to patched family protein n=1 Tax=Vitis vinifera
RepID=UPI0001985140
Length = 1018
Score = 222 bits (565), Expect = 1e-56
Identities = 113/129 (87%), Positives = 120/129 (93%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
IPFLVLA GVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASL+EVLAFAVG+F
Sbjct: 577 IPFLVLAVGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLAEVLAFAVGTF 636
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPD 377
I MPACRVFSMFAALAVLLDF+LQVTAFVALIV D RAED+R+DCFPCIK+ S +AD D
Sbjct: 637 IPMPACRVFSMFAALAVLLDFLLQVTAFVALIVFDFLRAEDRRIDCFPCIKISSSYADSD 696
Query: 378 KGIRQRKPG 404
KGI QRKPG
Sbjct: 697 KGIGQRKPG 705
[2][TOP]
>UniRef100_A7QPC0 Chromosome chr18 scaffold_137, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7QPC0_VITVI
Length = 1263
Score = 222 bits (565), Expect = 1e-56
Identities = 113/129 (87%), Positives = 120/129 (93%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
IPFLVLA GVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASL+EVLAFAVG+F
Sbjct: 668 IPFLVLAVGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLAEVLAFAVGTF 727
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPD 377
I MPACRVFSMFAALAVLLDF+LQVTAFVALIV D RAED+R+DCFPCIK+ S +AD D
Sbjct: 728 IPMPACRVFSMFAALAVLLDFLLQVTAFVALIVFDFLRAEDRRIDCFPCIKISSSYADSD 787
Query: 378 KGIRQRKPG 404
KGI QRKPG
Sbjct: 788 KGIGQRKPG 796
[3][TOP]
>UniRef100_A5APM6 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5APM6_VITVI
Length = 1050
Score = 222 bits (565), Expect = 1e-56
Identities = 113/129 (87%), Positives = 120/129 (93%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
IPFLVLA GVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASL+EVLAFAVG+F
Sbjct: 553 IPFLVLAVGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLAEVLAFAVGTF 612
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPD 377
I MPACRVFSMFAALAVLLDF+LQVTAFVALIV D RAED+R+DCFPCIK+ S +AD D
Sbjct: 613 IPMPACRVFSMFAALAVLLDFLLQVTAFVALIVFDFLRAEDRRIDCFPCIKISSSYADSD 672
Query: 378 KGIRQRKPG 404
KGI QRKPG
Sbjct: 673 KGIGQRKPG 681
[4][TOP]
>UniRef100_B9R8N7 Hedgehog receptor, putative n=1 Tax=Ricinus communis
RepID=B9R8N7_RICCO
Length = 1235
Score = 220 bits (560), Expect = 4e-56
Identities = 114/129 (88%), Positives = 118/129 (91%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
IPFLVLA GVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF
Sbjct: 648 IPFLVLAVGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 707
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPD 377
I MPACRVFSMFAALAVLLDF+LQVTAFVALIV D RAEDKRVDCFPC+K S +AD D
Sbjct: 708 IPMPACRVFSMFAALAVLLDFLLQVTAFVALIVFDFLRAEDKRVDCFPCLKTSSSYADSD 767
Query: 378 KGIRQRKPG 404
KGI R+PG
Sbjct: 768 KGIGGRRPG 776
[5][TOP]
>UniRef100_UPI0001982F17 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI0001982F17
Length = 1345
Score = 214 bits (546), Expect = 2e-54
Identities = 110/129 (85%), Positives = 116/129 (89%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
IPFLVLA GVDNMCILVHAVKRQ L+LPLEGRISNALVEVGPSITLASLSEVLAFAVGSF
Sbjct: 748 IPFLVLAVGVDNMCILVHAVKRQSLDLPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 807
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPD 377
I MPACRVFSMFAALAVLLDF+LQVTAFVALIV D RAED R+DCFPCIK+ S + D
Sbjct: 808 IPMPACRVFSMFAALAVLLDFLLQVTAFVALIVFDFMRAEDNRIDCFPCIKIPSSSVESD 867
Query: 378 KGIRQRKPG 404
+GI QRKPG
Sbjct: 868 EGINQRKPG 876
[6][TOP]
>UniRef100_A7P8Q4 Chromosome chr3 scaffold_8, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7P8Q4_VITVI
Length = 1217
Score = 214 bits (546), Expect = 2e-54
Identities = 110/129 (85%), Positives = 116/129 (89%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
IPFLVLA GVDNMCILVHAVKRQ L+LPLEGRISNALVEVGPSITLASLSEVLAFAVGSF
Sbjct: 620 IPFLVLAVGVDNMCILVHAVKRQSLDLPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 679
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPD 377
I MPACRVFSMFAALAVLLDF+LQVTAFVALIV D RAED R+DCFPCIK+ S + D
Sbjct: 680 IPMPACRVFSMFAALAVLLDFLLQVTAFVALIVFDFMRAEDNRIDCFPCIKIPSSSVESD 739
Query: 378 KGIRQRKPG 404
+GI QRKPG
Sbjct: 740 EGINQRKPG 748
[7][TOP]
>UniRef100_A5BXT3 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5BXT3_VITVI
Length = 692
Score = 203 bits (516), Expect = 6e-51
Identities = 103/121 (85%), Positives = 109/121 (90%)
Frame = +3
Query: 42 GVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFISMPACRV 221
GVDNMCILVHAVKRQ L+LPLEGRISNALVEVGPSITLASLSEVLAFAVGSFI MPACRV
Sbjct: 73 GVDNMCILVHAVKRQSLDLPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRV 132
Query: 222 FSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPDKGIRQRKP 401
FSMFAALAVLLDF+LQVTAFVALIV D RAED R+DCFPCIK+ S + D+GI QRKP
Sbjct: 133 FSMFAALAVLLDFLLQVTAFVALIVFDFMRAEDNRIDCFPCIKIPSSSVESDEGINQRKP 192
Query: 402 G 404
G
Sbjct: 193 G 193
[8][TOP]
>UniRef100_B9HPX9 Cholesterol transport protein n=1 Tax=Populus trichocarpa
RepID=B9HPX9_POPTR
Length = 1223
Score = 200 bits (508), Expect = 5e-50
Identities = 103/129 (79%), Positives = 112/129 (86%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
IPFLVLA GVDNMCILVHAVKRQ +EL +E RISNAL EVGPSITLASLSE+LAFAVGSF
Sbjct: 638 IPFLVLAVGVDNMCILVHAVKRQSIELAIEERISNALHEVGPSITLASLSEILAFAVGSF 697
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPD 377
I MPACRVFSMFAALAVLLDF+LQVTAFVALI D +RAED R+DCFPCIKV S +
Sbjct: 698 IPMPACRVFSMFAALAVLLDFLLQVTAFVALIAFDCRRAEDNRIDCFPCIKVPSSPGGSN 757
Query: 378 KGIRQRKPG 404
+GI QR+PG
Sbjct: 758 EGINQRRPG 766
[9][TOP]
>UniRef100_UPI000034F451 patched family protein n=1 Tax=Arabidopsis thaliana
RepID=UPI000034F451
Length = 1272
Score = 196 bits (498), Expect = 7e-49
Identities = 101/129 (78%), Positives = 110/129 (85%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
IPFLVLA GVDNMCILVHAVKRQ ELPLE RISNAL+EVGPSITLASL+E+LAFAVG+F
Sbjct: 666 IPFLVLAVGVDNMCILVHAVKRQEQELPLERRISNALMEVGPSITLASLAEILAFAVGAF 725
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPD 377
I MPA RVFSMFAALAVLLDF+LQ+TAFVALIV D +R EDKRVDCFPCIK +
Sbjct: 726 IKMPAVRVFSMFAALAVLLDFLLQITAFVALIVFDFRRTEDKRVDCFPCIKTSKSSISAE 785
Query: 378 KGIRQRKPG 404
KG+ QRK G
Sbjct: 786 KGVGQRKAG 794
[10][TOP]
>UniRef100_B9H5I2 Cholesterol transport protein n=1 Tax=Populus trichocarpa
RepID=B9H5I2_POPTR
Length = 1274
Score = 192 bits (488), Expect = 1e-47
Identities = 103/129 (79%), Positives = 108/129 (83%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
IPFLVLA GVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFA GSF
Sbjct: 676 IPFLVLAVGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAAGSF 735
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPD 377
I MPAC LAVLLDF+LQVTAFVALIV D RAEDKRVDC PC+K+ S +AD
Sbjct: 736 IPMPAC-------PLAVLLDFLLQVTAFVALIVFDFLRAEDKRVDCIPCMKISSSYADTP 788
Query: 378 KGIRQRKPG 404
KGI R+PG
Sbjct: 789 KGIGGRRPG 797
[11][TOP]
>UniRef100_UPI0001A7B126 hedgehog receptor n=1 Tax=Arabidopsis thaliana RepID=UPI0001A7B126
Length = 1234
Score = 186 bits (472), Expect = 7e-46
Identities = 96/129 (74%), Positives = 110/129 (85%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
IPFLVLA GVDNMCILVHAVKRQP E+ LE RIS+ALVEVGPSITLASLSEVLAFAVG+F
Sbjct: 640 IPFLVLAVGVDNMCILVHAVKRQPREVSLEQRISSALVEVGPSITLASLSEVLAFAVGAF 699
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPD 377
+ MPACR+FSMFAALA++LDF LQ+TAFVALIV D +R+ D R+DCFPCIKV S +
Sbjct: 700 VPMPACRIFSMFAALAIMLDFFLQITAFVALIVFDCKRSADNRIDCFPCIKVPSSSRESV 759
Query: 378 KGIRQRKPG 404
+G R+PG
Sbjct: 760 EG--GREPG 766
[12][TOP]
>UniRef100_Q9SVF0 Putative uncharacterized protein AT4g38350 n=1 Tax=Arabidopsis
thaliana RepID=Q9SVF0_ARATH
Length = 1055
Score = 186 bits (472), Expect = 7e-46
Identities = 96/129 (74%), Positives = 110/129 (85%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
IPFLVLA GVDNMCILVHAVKRQP E+ LE RIS+ALVEVGPSITLASLSEVLAFAVG+F
Sbjct: 614 IPFLVLAVGVDNMCILVHAVKRQPREVSLEQRISSALVEVGPSITLASLSEVLAFAVGAF 673
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPD 377
+ MPACR+FSMFAALA++LDF LQ+TAFVALIV D +R+ D R+DCFPCIKV S +
Sbjct: 674 VPMPACRIFSMFAALAIMLDFFLQITAFVALIVFDCKRSADNRIDCFPCIKVPSSSRESV 733
Query: 378 KGIRQRKPG 404
+G R+PG
Sbjct: 734 EG--GREPG 740
[13][TOP]
>UniRef100_B9SMD3 Putative uncharacterized protein n=1 Tax=Ricinus communis
RepID=B9SMD3_RICCO
Length = 584
Score = 184 bits (466), Expect = 4e-45
Identities = 93/117 (79%), Positives = 104/117 (88%)
Frame = +3
Query: 54 MCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFISMPACRVFSMF 233
MCILVHAVKRQ LE+ LE RISNALVEVGPSITLASLSE+LAFAVGSFI MPACRVFSMF
Sbjct: 1 MCILVHAVKRQSLEIALEERISNALVEVGPSITLASLSEILAFAVGSFIPMPACRVFSMF 60
Query: 234 AALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPDKGIRQRKPG 404
AALAVLLDF+LQVTAFVALIV D +RAED R+DCFPCIK+ S + ++G+ QR+PG
Sbjct: 61 AALAVLLDFLLQVTAFVALIVFDCKRAEDNRIDCFPCIKLSSSSEEMNEGVYQRRPG 117
[14][TOP]
>UniRef100_Q9SHN9 F7F22.1 n=1 Tax=Arabidopsis thaliana RepID=Q9SHN9_ARATH
Length = 1275
Score = 172 bits (437), Expect = 8e-42
Identities = 94/141 (66%), Positives = 103/141 (73%), Gaps = 20/141 (14%)
Frame = +3
Query: 42 GVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFISMPACRV 221
GVDNMCILVHAVKRQ ELPLE RISNAL+EVGPSITLASL+E+LAFAVG+FI MPA RV
Sbjct: 733 GVDNMCILVHAVKRQEQELPLERRISNALMEVGPSITLASLAEILAFAVGAFIKMPAVRV 792
Query: 222 FSMF--------------------AALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFP 341
FSMF AALAVLLDF+LQ+TAFVALIV D +R EDKRVDCFP
Sbjct: 793 FSMFAVYSLNAFIIYFLTSICIMLAALAVLLDFLLQITAFVALIVFDFRRTEDKRVDCFP 852
Query: 342 CIKVHSFHADPDKGIRQRKPG 404
CIK +KG+ QRK G
Sbjct: 853 CIKTSKSSISAEKGVGQRKAG 873
[15][TOP]
>UniRef100_Q7XUB7 OSJNBb0078D11.11 protein n=1 Tax=Oryza sativa Japonica Group
RepID=Q7XUB7_ORYSJ
Length = 1361
Score = 171 bits (433), Expect = 2e-41
Identities = 94/128 (73%), Positives = 102/128 (79%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
IPFLVLA GVDNMCILVHAVKRQP L LE RIS ALVEVGPSITLASL+EVLAFAV +
Sbjct: 677 IPFLVLAVGVDNMCILVHAVKRQPDGLDLEERISTALVEVGPSITLASLAEVLAFAVSAI 736
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPD 377
MPA RVFSMFAALAVLLDF+LQV+AFVALIVLD +RA+D R+DC PC +V S D
Sbjct: 737 NPMPATRVFSMFAALAVLLDFLLQVSAFVALIVLDFRRAQDGRIDCMPCARVKSSVVASD 796
Query: 378 KGIRQRKP 401
G Q P
Sbjct: 797 GGNHQGLP 804
[16][TOP]
>UniRef100_Q01KH5 H0409D10.4 protein n=1 Tax=Oryza sativa RepID=Q01KH5_ORYSA
Length = 1372
Score = 171 bits (433), Expect = 2e-41
Identities = 94/128 (73%), Positives = 102/128 (79%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
IPFLVLA GVDNMCILVHAVKRQP L LE RIS ALVEVGPSITLASL+EVLAFAV +
Sbjct: 677 IPFLVLAVGVDNMCILVHAVKRQPDGLDLEERISTALVEVGPSITLASLAEVLAFAVSAI 736
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPD 377
MPA RVFSMFAALAVLLDF+LQV+AFVALIVLD +RA+D R+DC PC +V S D
Sbjct: 737 NPMPATRVFSMFAALAVLLDFLLQVSAFVALIVLDFRRAQDGRIDCMPCARVKSSVVASD 796
Query: 378 KGIRQRKP 401
G Q P
Sbjct: 797 GGNHQGLP 804
[17][TOP]
>UniRef100_B8AT56 Putative uncharacterized protein n=1 Tax=Oryza sativa Indica Group
RepID=B8AT56_ORYSI
Length = 1257
Score = 171 bits (433), Expect = 2e-41
Identities = 94/128 (73%), Positives = 102/128 (79%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
IPFLVLA GVDNMCILVHAVKRQP L LE RIS ALVEVGPSITLASL+EVLAFAV +
Sbjct: 635 IPFLVLAVGVDNMCILVHAVKRQPDGLDLEERISTALVEVGPSITLASLAEVLAFAVSAI 694
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPD 377
MPA RVFSMFAALAVLLDF+LQV+AFVALIVLD +RA+D R+DC PC +V S D
Sbjct: 695 NPMPATRVFSMFAALAVLLDFLLQVSAFVALIVLDFRRAQDGRIDCMPCARVKSSVVASD 754
Query: 378 KGIRQRKP 401
G Q P
Sbjct: 755 GGNHQGLP 762
[18][TOP]
>UniRef100_A9SMZ7 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9SMZ7_PHYPA
Length = 1170
Score = 169 bits (428), Expect = 9e-41
Identities = 87/129 (67%), Positives = 102/129 (79%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
IPFLVLA GVDNMCILV+A+KRQ L L LE R+ AL EVGPSITLASL+EVLAFAVGSF
Sbjct: 661 IPFLVLAVGVDNMCILVNALKRQDLSLQLESRVGLALAEVGPSITLASLAEVLAFAVGSF 720
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPD 377
MPACRVFS+FAA+AVLLD++LQ+TAFVAL+ LD +R+E RVDC PC+ V
Sbjct: 721 TPMPACRVFSLFAAVAVLLDYLLQITAFVALLTLDFRRSESGRVDCIPCMSVELCFVSGS 780
Query: 378 KGIRQRKPG 404
+QR+PG
Sbjct: 781 STRQQREPG 789
[19][TOP]
>UniRef100_C7J1V6 Os04g0563801 protein n=1 Tax=Oryza sativa Japonica Group
RepID=C7J1V6_ORYSJ
Length = 963
Score = 160 bits (404), Expect = 5e-38
Identities = 87/125 (69%), Positives = 97/125 (77%)
Frame = +3
Query: 27 LVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFISM 206
+ + GVDNMCILVHAVKRQP L LE RIS ALVEVGPSITLASL+EVLAFAV + M
Sbjct: 494 ITIVVGVDNMCILVHAVKRQPDGLDLEERISTALVEVGPSITLASLAEVLAFAVSAINPM 553
Query: 207 PACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPDKGI 386
PA RVFSMFAALAVLLDF+LQV+AFVALIVLD +RA+D R+DC PC +V S D G
Sbjct: 554 PATRVFSMFAALAVLLDFLLQVSAFVALIVLDFRRAQDGRIDCMPCARVKSSVVASDGGN 613
Query: 387 RQRKP 401
Q P
Sbjct: 614 HQGLP 618
[20][TOP]
>UniRef100_B9FBZ9 Putative uncharacterized protein n=1 Tax=Oryza sativa Japonica
Group RepID=B9FBZ9_ORYSJ
Length = 1211
Score = 159 bits (403), Expect = 7e-38
Identities = 87/120 (72%), Positives = 95/120 (79%)
Frame = +3
Query: 42 GVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFISMPACRV 221
GVDNMCILVHAVKRQP L LE RIS ALVEVGPSITLASL+EVLAFAV + MPA RV
Sbjct: 625 GVDNMCILVHAVKRQPDGLDLEERISTALVEVGPSITLASLAEVLAFAVSAINPMPATRV 684
Query: 222 FSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPDKGIRQRKP 401
FSMFAALAVLLDF+LQV+AFVALIVLD +RA+D R+DC PC +V S D G Q P
Sbjct: 685 FSMFAALAVLLDFLLQVSAFVALIVLDFRRAQDGRIDCMPCARVKSSVVASDGGNHQGLP 744
[21][TOP]
>UniRef100_A9RFW8 Predicted protein (Fragment) n=1 Tax=Physcomitrella patens subsp.
patens RepID=A9RFW8_PHYPA
Length = 1262
Score = 157 bits (396), Expect = 5e-37
Identities = 80/112 (71%), Positives = 93/112 (83%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
IPFLVLA GVDNMCILVHA+KRQ L L LE R+ AL EVGPSITLAS++EVLAF VG
Sbjct: 630 IPFLVLAVGVDNMCILVHALKRQDLNLNLETRVGLALAEVGPSITLASVAEVLAFTVGIS 689
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
MPACRVFS+FAA+AVLLD++LQ+TAFVA++ LD +R+E RVDC PCI V
Sbjct: 690 TPMPACRVFSLFAAVAVLLDYLLQITAFVAVLTLDFRRSESGRVDCVPCIHV 741
[22][TOP]
>UniRef100_B2APT9 Predicted CDS Pa_4_6310 n=1 Tax=Podospora anserina RepID=B2APT9_PODAN
Length = 1278
Score = 116 bits (290), Expect = 9e-25
Identities = 57/117 (48%), Positives = 85/117 (72%), Gaps = 3/117 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPF+VLA GVDN+ ++VH +R L P +E R+S AL +GPSI ++++E + FA+
Sbjct: 671 IPFIVLAVGVDNIFLIVHEFERVNLSHPDDMVEQRVSRALGRMGPSILFSAITETICFAL 730
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHS 359
G+F+ MPA R F+++AA AV ++ +LQVT F++++ L+ RAED R DCFPCI+V S
Sbjct: 731 GAFVGMPAVRNFAIYAAGAVFINAILQVTMFISVLTLNQIRAEDSRADCFPCIQVKS 787
[23][TOP]
>UniRef100_Q9TVK6 Niemann-Pick C type protein n=1 Tax=Dictyostelium discoideum
RepID=Q9TVK6_DICDI
Length = 1342
Score = 115 bits (289), Expect = 1e-24
Identities = 66/121 (54%), Positives = 83/121 (68%), Gaps = 11/121 (9%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILV------HAVKRQPLE----LPL-EGRISNALVEVGPSITLASL 164
IPFLVLA GVDN+ I+V H V+ P LP E ++ L +VGPSI LASL
Sbjct: 737 IPFLVLAIGVDNIFIIVNTFESLHVVRYDPHTRAAILPTSEDSLARTLAKVGPSIALASL 796
Query: 165 SEVLAFAVGSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
SE LAF +GS MPA + FS +AALA+ +DF+LQV+AF AL+VLDS+RA +R+DC PC
Sbjct: 797 SESLAFLLGSLTKMPAVQAFSYYAALAIFVDFLLQVSAFSALLVLDSKRASSRRIDCLPC 856
Query: 345 I 347
I
Sbjct: 857 I 857
[24][TOP]
>UniRef100_Q7RWL9 Putative uncharacterized protein n=1 Tax=Neurospora crassa
RepID=Q7RWL9_NEUCR
Length = 1162
Score = 115 bits (288), Expect = 2e-24
Identities = 57/117 (48%), Positives = 84/117 (71%), Gaps = 3/117 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPF+VLA GVDN+ ++VH +R + P +E RIS AL +GPSI ++L+E +FA+
Sbjct: 554 IPFIVLAVGVDNIFLIVHEFERVNVSYPDDMVEARISRALGRMGPSILFSALTETASFAL 613
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHS 359
G+F+ MPA R F+++AA AV ++ +LQVT FV+++ L+ R ED R DCFPCI++ S
Sbjct: 614 GAFVGMPAVRNFAIYAAGAVFINAILQVTMFVSVLTLNQIRVEDSRADCFPCIQIKS 670
[25][TOP]
>UniRef100_Q0U4X8 Putative uncharacterized protein n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U4X8_PHANO
Length = 1277
Score = 114 bits (285), Expect = 3e-24
Identities = 61/122 (50%), Positives = 85/122 (69%), Gaps = 3/122 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH +R + P + R+S AL +GPSI L++L+E AFA+
Sbjct: 673 IPFLVLAVGVDNIFLIVHEFERVNISHPEGTIPERVSRALGRMGPSILLSALTETTAFAL 732
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHA 368
G + MPA R F+ +AA AVL++ +LQVT F+A++ L+ QR E+ R DCFPCI+V A
Sbjct: 733 GCAVGMPAVRNFAAYAAGAVLINALLQVTMFIAVLALNQQRVENNRADCFPCIRVSK--A 790
Query: 369 DP 374
DP
Sbjct: 791 DP 792
[26][TOP]
>UniRef100_A7EA90 Putative uncharacterized protein n=1 Tax=Sclerotinia sclerotiorum
1980 UF-70 RepID=A7EA90_SCLS1
Length = 1252
Score = 114 bits (284), Expect = 4e-24
Identities = 60/142 (42%), Positives = 94/142 (66%), Gaps = 16/142 (11%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPF+VLA GVDN+ ++VH +R P +E RI+ AL +GPSI L++ +E +AFA+
Sbjct: 650 IPFIVLAVGVDNIFLIVHEFERVNTNHPDEMVEMRIAKALGRMGPSILLSASTETIAFAL 709
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHS--- 359
G+F+ MPA R F+++AA AV ++ VLQ+T FV+++ L+ +R ED+RVDC PCI++ +
Sbjct: 710 GAFVGMPAVRNFAIYAAGAVFINAVLQITMFVSILSLNQRRVEDRRVDCIPCIQIKTAGV 769
Query: 360 ----------FHADPDKGIRQR 395
F+ D+G+ Q+
Sbjct: 770 HLGNGSAYSRFYEGSDEGVLQK 791
[27][TOP]
>UniRef100_C9SSK4 Niemann-Pick C1 protein n=1 Tax=Verticillium albo-atrum VaMs.102
RepID=C9SSK4_9PEZI
Length = 552
Score = 113 bits (283), Expect = 6e-24
Identities = 55/115 (47%), Positives = 84/115 (73%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPF+VLA GVDN+ ++VH +R + P +E R++ AL +GPSI L++L+E ++FA+
Sbjct: 234 IPFIVLAVGVDNIFLIVHEFERVNVSHPDSMVEERVAKALGRMGPSILLSALTETVSFAL 293
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
G+F+ MPA R F+ +AA AV ++ +LQ+T FV+++ L+ R ED R DCFPCI+V
Sbjct: 294 GAFVGMPAVRNFAAYAAGAVFINAILQITMFVSVLALNQMRVEDHRADCFPCIQV 348
[28][TOP]
>UniRef100_C1GRY4 Patched sphingolipid transporter (Ncr1) n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GRY4_PARBA
Length = 1266
Score = 113 bits (282), Expect = 8e-24
Identities = 57/115 (49%), Positives = 84/115 (73%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL---ELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH +R L E ++GRI+ AL +GPSI L++ +E +AFA+
Sbjct: 665 IPFLVLAIGVDNIFLIVHEFERVNLSHQEEEIDGRIARALGRMGPSILLSAATETIAFAM 724
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
G+F+ MPA + F+ +AA AVL++ +LQVT FV+++ L+ +R E R DCFPC+ V
Sbjct: 725 GAFVGMPAVKNFAAYAAGAVLINAILQVTMFVSVLALNQRRVESLRADCFPCLTV 779
[29][TOP]
>UniRef100_C1G8F9 Niemann-Pick C1 protein n=1 Tax=Paracoccidioides brasiliensis Pb18
RepID=C1G8F9_PARBD
Length = 1235
Score = 113 bits (282), Expect = 8e-24
Identities = 57/115 (49%), Positives = 84/115 (73%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL---ELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH +R L E ++GRI+ AL +GPSI L++ +E +AFA+
Sbjct: 665 IPFLVLAIGVDNIFLIVHEFERVNLSHQEEEIDGRIARALGRMGPSILLSAATETIAFAM 724
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
G+F+ MPA + F+ +AA AVL++ +LQVT FV+++ L+ +R E R DCFPC+ V
Sbjct: 725 GAFVGMPAVKNFAAYAAGAVLINAILQVTMFVSVLALNQRRVESLRADCFPCLTV 779
[30][TOP]
>UniRef100_C0S090 Niemann-Pick C1 protein n=1 Tax=Paracoccidioides brasiliensis Pb03
RepID=C0S090_PARBP
Length = 1235
Score = 113 bits (282), Expect = 8e-24
Identities = 57/115 (49%), Positives = 84/115 (73%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL---ELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH +R L E ++GRI+ AL +GPSI L++ +E +AFA+
Sbjct: 665 IPFLVLAIGVDNIFLIVHEFERVNLSHQEEEIDGRIARALGRMGPSILLSAATETIAFAM 724
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
G+F+ MPA + F+ +AA AVL++ +LQVT FV+++ L+ +R E R DCFPC+ V
Sbjct: 725 GAFVGMPAVKNFAAYAAGAVLINAILQVTMFVSVLALNQRRVESLRADCFPCLTV 779
[31][TOP]
>UniRef100_Q2U2G2 Cholesterol transport protein n=1 Tax=Aspergillus oryzae
RepID=Q2U2G2_ASPOR
Length = 1163
Score = 112 bits (281), Expect = 1e-23
Identities = 55/120 (45%), Positives = 85/120 (70%), Gaps = 3/120 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH +R + P ++ R++ A +GPSI L+SL+E +AFA+
Sbjct: 563 IPFLVLAVGVDNIFLIVHEFERINVSHPDEEIDERLARAAGRIGPSIFLSSLTETVAFAL 622
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHA 368
G+F+ MPA + F+++AA AV ++ VLQ+T F++++ L+ +R E R DCFPCI V H+
Sbjct: 623 GAFVGMPAVKNFAVYAAGAVFINAVLQITMFISVLALNQRRVESLRADCFPCITVRKAHS 682
[32][TOP]
>UniRef100_B3S409 Putative uncharacterized protein (Fragment) n=1 Tax=Trichoplax
adhaerens RepID=B3S409_TRIAD
Length = 1218
Score = 112 bits (280), Expect = 1e-23
Identities = 62/114 (54%), Positives = 81/114 (71%), Gaps = 3/114 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR---QPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
+PFLVLA GVDNM ILV AV+R QP E +E +I L V PS+ L SLSE +AF++
Sbjct: 644 VPFLVLAVGVDNMFILVQAVQRDTRQPQE-EIEQQIGRVLGTVAPSMLLTSLSETIAFSL 702
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
G+ +MPA R FS++AALAV +DF+LQVT FVAL+ LD++R + R D C+K
Sbjct: 703 GAISTMPAVRTFSIYAALAVFIDFLLQVTCFVALLCLDTKRENNNRYDVLCCVK 756
[33][TOP]
>UniRef100_C4JHE8 Putative uncharacterized protein n=1 Tax=Uncinocarpus reesii 1704
RepID=C4JHE8_UNCRE
Length = 1271
Score = 112 bits (279), Expect = 2e-23
Identities = 57/115 (49%), Positives = 84/115 (73%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH +R + P L+ RI+ AL +GPSI L++ +E +AFA+
Sbjct: 671 IPFLVLAVGVDNIFLIVHEFERVNVSHPDEELDERIAKALGRMGPSILLSATTETVAFAM 730
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
G F+ MPA + F+++AA AVL++ +LQVT F++L+ L+ +R E RVDCFPC+ V
Sbjct: 731 GVFVGMPAVKNFAVYAAGAVLINALLQVTMFISLLALNQRRVESLRVDCFPCLTV 785
[34][TOP]
>UniRef100_Q2GRY0 Putative uncharacterized protein n=1 Tax=Chaetomium globosum
RepID=Q2GRY0_CHAGB
Length = 1181
Score = 111 bits (278), Expect = 2e-23
Identities = 56/117 (47%), Positives = 83/117 (70%), Gaps = 3/117 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPF+VLA GVDN+ ++VH +R + P +E RIS AL +GPSI ++++E FA+
Sbjct: 573 IPFIVLAVGVDNIFLIVHEFERVNISHPDDVVEVRISRALGRMGPSILFSAITETACFAL 632
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHS 359
G+F+ MPA R F+++AA AV ++ +LQVT FV+++ L+ R ED R DCFPC++V S
Sbjct: 633 GAFVGMPAVRNFAIYAAGAVFINAILQVTMFVSVLTLNQIRVEDFRADCFPCVQVKS 689
[35][TOP]
>UniRef100_Q1E7S9 Putative uncharacterized protein n=1 Tax=Coccidioides immitis
RepID=Q1E7S9_COCIM
Length = 1203
Score = 111 bits (278), Expect = 2e-23
Identities = 57/115 (49%), Positives = 83/115 (72%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH +R L P L+ RI+ AL +GPSI L++ +E +AFA+
Sbjct: 671 IPFLVLAVGVDNIFLIVHEFERVNLSHPEEELDERIAKALGRMGPSILLSAATETIAFAM 730
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
G F+ MPA + F+++AA AV ++ +LQVT F++L+ L+ +R E RVDCFPC+ V
Sbjct: 731 GVFVGMPAVKNFAIYAAGAVFINALLQVTMFISLLCLNQRRVESLRVDCFPCLTV 785
[36][TOP]
>UniRef100_Q0CK25 Putative uncharacterized protein n=1 Tax=Aspergillus terreus NIH2624
RepID=Q0CK25_ASPTN
Length = 1263
Score = 111 bits (278), Expect = 2e-23
Identities = 56/133 (42%), Positives = 90/133 (67%), Gaps = 4/133 (3%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH +R + P ++ RI+ A +GPSI L++++E +AFA+
Sbjct: 663 IPFLVLAVGVDNIFLIVHEFERINVSHPDEEIDQRIARAAGRIGPSIFLSAITETVAFAL 722
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHA 368
G+F+ MPA R F+++AA AV ++ +LQ+T F++++ L+ +R E R DCFPC+ V H+
Sbjct: 723 GAFVGMPAVRNFAVYAAGAVFINALLQITMFISVLALNQRRVESLRADCFPCVTVRKAHS 782
Query: 369 D-PDKGIRQRKPG 404
P+ I + G
Sbjct: 783 GMPEDHIYDEQDG 795
[37][TOP]
>UniRef100_C5PGL6 Patched family protein n=1 Tax=Coccidioides posadasii C735 delta
SOWgp RepID=C5PGL6_COCP7
Length = 1271
Score = 111 bits (278), Expect = 2e-23
Identities = 57/115 (49%), Positives = 83/115 (72%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH +R L P L+ RI+ AL +GPSI L++ +E +AFA+
Sbjct: 671 IPFLVLAVGVDNIFLIVHEFERVNLSHPEEELDERIAKALGRMGPSILLSAATETIAFAM 730
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
G F+ MPA + F+++AA AV ++ +LQVT F++L+ L+ +R E RVDCFPC+ V
Sbjct: 731 GVFVGMPAVKNFAIYAAGAVFINALLQVTMFISLLCLNQRRVESLRVDCFPCLTV 785
[38][TOP]
>UniRef100_B0CUV0 Predicted protein n=1 Tax=Laccaria bicolor S238N-H82
RepID=B0CUV0_LACBS
Length = 1341
Score = 110 bits (276), Expect = 4e-23
Identities = 61/140 (43%), Positives = 84/140 (60%), Gaps = 28/140 (20%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQ----------------------------PLELPLEGR 113
IPFLVLA GVDN+ ILVH + RQ PL LP E R
Sbjct: 703 IPFLVLAVGVDNVFILVHELDRQNLLHAPMSPTNSSRSPFESTNDVDASSMPLYLPAEER 762
Query: 114 ISNALVEVGPSITLASLSEVLAFAVGSFISMPACRVFSMFAALAVLLDFVLQVTAFVALI 293
+ AL ++GPSI L++++E AFA+G+ + MPA R F+++AA +V L+ LQVT FV+ +
Sbjct: 763 VGRALAKMGPSILLSTITETTAFALGALVPMPAVRNFALYAAGSVFLNATLQVTVFVSAL 822
Query: 294 VLDSQRAEDKRVDCFPCIKV 353
+LD +R E RVDC PCI++
Sbjct: 823 LLDLKRVESSRVDCLPCIRL 842
[39][TOP]
>UniRef100_C5FQM2 Niemann-Pick C1 protein n=1 Tax=Microsporum canis CBS 113480
RepID=C5FQM2_NANOT
Length = 1270
Score = 110 bits (275), Expect = 5e-23
Identities = 57/115 (49%), Positives = 82/115 (71%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH +R L P ++ RI+ AL +GPSI L++ +E +AFA+
Sbjct: 668 IPFLVLAVGVDNIFLIVHEFERVNLSHPDDEIDERIARALGRIGPSILLSATTETIAFAL 727
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
G F+ MPA + F+ +AA AVL++ +LQVT FV+++ L+ +R E RVDC PCI V
Sbjct: 728 GVFVGMPAVKNFAAYAAGAVLINALLQVTMFVSILALNQKRVESLRVDCVPCIAV 782
[40][TOP]
>UniRef100_C8VM00 Putative uncharacterized protein n=2 Tax=Emericella nidulans
RepID=C8VM00_EMENI
Length = 1271
Score = 109 bits (272), Expect = 1e-22
Identities = 54/120 (45%), Positives = 84/120 (70%), Gaps = 3/120 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++V+ +R + P ++ RIS A+ +GPSI L++++E +AFA+
Sbjct: 671 IPFLVLAVGVDNIFLIVYEFERLNVSHPDEEIDERISRAIGRIGPSIFLSAITETVAFAL 730
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHA 368
G F+ MPA R F+++AA AV ++ VLQ+T FV+++ L+ +R E R DC PC+ V H+
Sbjct: 731 GVFVGMPAVRNFAIYAAGAVFINAVLQITMFVSVLALNQKRVESLRADCIPCLTVRKAHS 790
[41][TOP]
>UniRef100_B2W9M2 Niemann-Pick C1 protein n=1 Tax=Pyrenophora tritici-repentis
Pt-1C-BFP RepID=B2W9M2_PYRTR
Length = 1265
Score = 108 bits (270), Expect = 2e-22
Identities = 56/115 (48%), Positives = 78/115 (67%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH +R + P + R+S AL +GPSI L++L+E AFA+
Sbjct: 662 IPFLVLAVGVDNIFLIVHEFERINISHPEGTIPERVSRALGRMGPSILLSALTETTAFAL 721
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
G + MPA R F+ +AA AV ++ +LQVT F A++ L+ QR E R DCFPC+ V
Sbjct: 722 GCAVGMPAVRNFAAYAAGAVFINAILQVTMFTAVLALNQQRVETNRADCFPCVTV 776
[42][TOP]
>UniRef100_A2QWF9 Remark: Niemann-Pick C n=1 Tax=Aspergillus niger CBS 513.88
RepID=A2QWF9_ASPNC
Length = 1277
Score = 108 bits (270), Expect = 2e-22
Identities = 53/120 (44%), Positives = 83/120 (69%), Gaps = 3/120 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH +R + P ++ RI+ A+ +GPSI L++L+E +AF +
Sbjct: 677 IPFLVLAVGVDNIFLIVHEFERINVSHPDEEIDERIARAVGRIGPSIFLSALTETVAFVM 736
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHA 368
G F+ MPA R F+++AA AV ++ VLQ+T F++++ L+ +R E R DC PC+ V H+
Sbjct: 737 GVFVGMPAVRNFAVYAAGAVFINAVLQITMFISVLALNQRRVESLRADCIPCLTVRKAHS 796
[43][TOP]
>UniRef100_B6QA78 Patched sphingolipid transporter (Ncr1), putative n=1 Tax=Penicillium
marneffei ATCC 18224 RepID=B6QA78_PENMQ
Length = 1269
Score = 107 bits (268), Expect = 3e-22
Identities = 54/115 (46%), Positives = 79/115 (68%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH R + P ++ RI AL +GPSI L++++E +AFA+
Sbjct: 668 IPFLVLAVGVDNIFLIVHEFDRVNISHPDEEIDERIGRALGRMGPSILLSAITETVAFAM 727
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
G F+ MPA + F+ +AA AV ++ +LQVT F+A++ L+ +R E R DCFPC V
Sbjct: 728 GIFVGMPAVKNFAAYAAGAVFINAILQVTMFIAVLALNQRRVESLRADCFPCFTV 782
[44][TOP]
>UniRef100_A4RE01 Putative uncharacterized protein n=1 Tax=Magnaporthe grisea
RepID=A4RE01_MAGGR
Length = 1275
Score = 107 bits (268), Expect = 3e-22
Identities = 54/117 (46%), Positives = 85/117 (72%), Gaps = 3/117 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL---ELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPF+VLA GVDN+ ++VH +R + +L +E RI+ AL +GPSI ++++E +FA+
Sbjct: 669 IPFIVLAVGVDNIFLIVHEFERVNISHPDLDVELRIAKALGRMGPSILFSAVTETASFAL 728
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHS 359
G+F+ MPA R F+++AA AV ++ +LQVT FV+ + L+ QR ED R+D FPC+++ S
Sbjct: 729 GAFVGMPAVRNFAIYAAGAVFINALLQVTMFVSFLTLNQQRVEDCRMDLFPCVQLKS 785
[45][TOP]
>UniRef100_C4Q7T0 Niemann-pick C1 (NPC1) n=1 Tax=Schistosoma mansoni
RepID=C4Q7T0_SCHMA
Length = 950
Score = 107 bits (267), Expect = 4e-22
Identities = 59/123 (47%), Positives = 84/123 (68%), Gaps = 8/123 (6%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR-------QPLELPLEGRISNALVEVGPSITLASLSEVL 176
IPFLVLA GVDN+ ILVH + +P++L +E RIS ++ VGPS+ L SLSE +
Sbjct: 265 IPFLVLAIGVDNIFILVHEFEHNQLNNLNEPIKLLVEDRISESMGSVGPSMLLTSLSESV 324
Query: 177 AFAVGSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV- 353
AF G+ +MPA RVF+++AA+A++ +F+LQ+ AFVAL+ LD +R +R D C K+
Sbjct: 325 AFFCGALTTMPAVRVFALYAAMAIVFNFLLQIFAFVALLTLDGRRYVARRFDVLFCFKLK 384
Query: 354 HSF 362
H F
Sbjct: 385 HEF 387
[46][TOP]
>UniRef100_B8M187 Patched sphingolipid transporter (Ncr1), putative n=1 Tax=Talaromyces
stipitatus ATCC 10500 RepID=B8M187_TALSN
Length = 1269
Score = 107 bits (267), Expect = 4e-22
Identities = 53/115 (46%), Positives = 79/115 (68%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH R + P ++ R+ AL +GPSI L++++E +AFA+
Sbjct: 668 IPFLVLAVGVDNIFLIVHEFDRVNISHPDEEIDERVGRALGRMGPSILLSAITETVAFAM 727
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
G F+ MPA + F+ +AA AV ++ +LQVT F+A++ L+ +R E R DCFPC V
Sbjct: 728 GIFVGMPAVKNFAAYAAGAVFMNAILQVTMFIAVLALNQRRVESLRADCFPCFTV 782
[47][TOP]
>UniRef100_C4M8X7 Niemann-Pick C1 protein, putative n=1 Tax=Entamoeba histolytica
HM-1:IMSS RepID=C4M8X7_ENTHI
Length = 1339
Score = 107 bits (266), Expect = 5e-22
Identities = 55/124 (44%), Positives = 81/124 (65%), Gaps = 6/124 (4%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLE------LPLEGRISNALVEVGPSITLASLSEVLA 179
IPFLVLA GVDN+ IL + + QP+ +P+E R+ ++L+ VGPS+ LAS+SE LA
Sbjct: 746 IPFLVLAIGVDNIFILTNTIDEQPMYDKDGQYVPVEKRLEHSLMHVGPSMMLASISESLA 805
Query: 180 FAVGSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHS 359
F +G SMPA + FS++A LA+ +DF+LQ+T + L+ D +R E +D P ++VH
Sbjct: 806 FFLGYLTSMPAVQSFSLYAGLAIFIDFILQITVYAVLLCYDVKRQESHGLDFIPWLQVHD 865
Query: 360 FHAD 371
D
Sbjct: 866 NSLD 869
[48][TOP]
>UniRef100_B0E9R8 Niemann-Pick C1 protein, putative n=1 Tax=Entamoeba dispar SAW760
RepID=B0E9R8_ENTDI
Length = 1320
Score = 107 bits (266), Expect = 5e-22
Identities = 55/124 (44%), Positives = 81/124 (65%), Gaps = 6/124 (4%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLE------LPLEGRISNALVEVGPSITLASLSEVLA 179
IPFLVLA GVDN+ IL + + QP+ +P+E R+ ++L+ VGPS+ LAS+SE LA
Sbjct: 727 IPFLVLAIGVDNIFILTNTIDEQPMYDKDGQYVPVEKRLEHSLMHVGPSMMLASISESLA 786
Query: 180 FAVGSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHS 359
F +G SMPA + FS++A LA+ +DF+LQ+T + L+ D +R E +D P ++VH
Sbjct: 787 FFLGYLTSMPAVQSFSLYAGLAIFIDFILQITVYAVLLCYDVKRQESHGLDFIPWLQVHD 846
Query: 360 FHAD 371
D
Sbjct: 847 NSLD 850
[49][TOP]
>UniRef100_Q4WMG5 Patched sphingolipid transporter (Ncr1), putative n=1 Tax=Aspergillus
fumigatus RepID=Q4WMG5_ASPFU
Length = 1273
Score = 107 bits (266), Expect = 5e-22
Identities = 53/115 (46%), Positives = 82/115 (71%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH +R + P ++ R++ A+ +GPSI L++L+E +AFA+
Sbjct: 672 IPFLVLAVGVDNIFLIVHEFERINVSHPDEEIDERVARAVGRIGPSIFLSALTETVAFAL 731
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
G F+ MPA R F+++AA AV ++ +LQ+T FV+++ L+ +R E R DC PCI V
Sbjct: 732 GVFVGMPAVRNFAIYAAGAVFINAILQMTMFVSVLALNQRRVESLRADCIPCITV 786
[50][TOP]
>UniRef100_B0Y842 Patched sphingolipid transporter (Ncr1), putative n=1 Tax=Aspergillus
fumigatus A1163 RepID=B0Y842_ASPFC
Length = 1273
Score = 107 bits (266), Expect = 5e-22
Identities = 53/115 (46%), Positives = 82/115 (71%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH +R + P ++ R++ A+ +GPSI L++L+E +AFA+
Sbjct: 672 IPFLVLAVGVDNIFLIVHEFERINVSHPDEEIDERVARAVGRIGPSIFLSALTETVAFAL 731
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
G F+ MPA R F+++AA AV ++ +LQ+T FV+++ L+ +R E R DC PCI V
Sbjct: 732 GVFVGMPAVRNFAIYAAGAVFINAILQMTMFVSVLALNQRRVESLRADCIPCITV 786
[51][TOP]
>UniRef100_A1DN50 Patched sphingolipid transporter (Ncr1), putative n=1 Tax=Neosartorya
fischeri NRRL 181 RepID=A1DN50_NEOFI
Length = 1273
Score = 107 bits (266), Expect = 5e-22
Identities = 53/115 (46%), Positives = 82/115 (71%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH +R + P ++ R++ A+ +GPSI L++L+E +AFA+
Sbjct: 672 IPFLVLAVGVDNIFLIVHEFERINVSHPDEEIDERVARAVGRIGPSIFLSALTETVAFAL 731
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
G F+ MPA R F+++AA AV ++ +LQ+T FV+++ L+ +R E R DC PCI V
Sbjct: 732 GVFVGMPAVRNFAIYAAGAVFINAILQMTMFVSVLALNQRRVESLRADCIPCITV 786
[52][TOP]
>UniRef100_C3ZSN0 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
RepID=C3ZSN0_BRAFL
Length = 1368
Score = 106 bits (265), Expect = 7e-22
Identities = 56/114 (49%), Positives = 78/114 (68%), Gaps = 2/114 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFLVLA GVDN+ ILV A +R LE +I+ L +V PS+ L S SE +AF +G
Sbjct: 759 VPFLVLAVGVDNIFILVQAFQRDERRKNEELEDQIARILGQVAPSLFLTSFSETVAFCLG 818
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
+MPA RVFS++A LAV DF+LQ+T FV+L+ +D++R E+ R+D C+KV
Sbjct: 819 GLSNMPAVRVFSLYAGLAVFFDFLLQITCFVSLLTIDARRQENNRMDFCCCVKV 872
[53][TOP]
>UniRef100_UPI000180B49C PREDICTED: Niemann-Pick disease, type C3 n=1 Tax=Ciona intestinalis
RepID=UPI000180B49C
Length = 1313
Score = 106 bits (264), Expect = 9e-22
Identities = 59/126 (46%), Positives = 78/126 (61%), Gaps = 3/126 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR---QPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFL LA GVDN+ ILV +R QP E P E R+ L EV PS+ ++S+SE +AF +
Sbjct: 698 IPFLALAVGVDNIFILVQHYQRDNWQPRETP-EERLGRVLGEVAPSMFMSSISETVAFFL 756
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHA 368
G +MPA R FSM A LA+ DF+LQ++ FVA++ LD++R R DC CIK
Sbjct: 757 GGLSTMPAVRTFSMMAGLAIFCDFLLQISCFVAILALDNKRQNSNRFDCLCCIKDKENEE 816
Query: 369 DPDKGI 386
+ GI
Sbjct: 817 SENDGI 822
[54][TOP]
>UniRef100_Q7PS03 AGAP000579-PA (Fragment) n=1 Tax=Anopheles gambiae RepID=Q7PS03_ANOGA
Length = 1247
Score = 106 bits (264), Expect = 9e-22
Identities = 61/131 (46%), Positives = 81/131 (61%), Gaps = 2/131 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGR--ISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ +LVHA R E E I AL ++GPSI L S SE FA+G
Sbjct: 662 IPFLVLAVGVDNIFMLVHAFNRIDRERTPETACAIGEALGQIGPSILLTSASECCCFAIG 721
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHAD 371
+ MPA F+ +A +A+L+DF+LQ++AFVAL+ LD QR E R+D C++ +
Sbjct: 722 ALSPMPAVNTFAWYATVALLVDFLLQISAFVALMALDEQRVERGRLDLVCCVRATK---N 778
Query: 372 PDKGIRQRKPG 404
PDK + PG
Sbjct: 779 PDKPVAPDGPG 789
[55][TOP]
>UniRef100_Q551C5 Putative uncharacterized protein n=1 Tax=Dictyostelium discoideum
RepID=Q551C5_DICDI
Length = 1397
Score = 106 bits (264), Expect = 9e-22
Identities = 58/136 (42%), Positives = 84/136 (61%), Gaps = 18/136 (13%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL-----------------ELPL-EGRISNALVEVGP 143
IPFLVLA GVDN+ ILV+ + + ++P E + L +VGP
Sbjct: 735 IPFLVLAIGVDNIFILVNTFESLHVASSSSSSSISGFNQNHHQMPTPEESFARTLAKVGP 794
Query: 144 SITLASLSEVLAFAVGSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDK 323
SI LASLSE AF +GS MPA + FS +A++AV DF+LQ++AF L+VLD++R + +
Sbjct: 795 SIALASLSESFAFLLGSLTKMPAVKAFSFYASIAVFFDFLLQISAFACLLVLDTKRLQSR 854
Query: 324 RVDCFPCIKVHSFHAD 371
RVDC PC+ ++ ++D
Sbjct: 855 RVDCLPCLSLNGDNSD 870
[56][TOP]
>UniRef100_UPI0000586B35 PREDICTED: similar to Niemann-Pick C disease protein n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000586B35
Length = 1332
Score = 105 bits (262), Expect = 2e-21
Identities = 62/132 (46%), Positives = 81/132 (61%), Gaps = 3/132 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGR---ISNALVEVGPSITLASLSEVLAFAV 188
+PFLVLA GVDN+ ILV +R P E R I L EV PS+ L S SE +AF +
Sbjct: 730 VPFLVLAVGVDNIFILVQRYQRDE-RYPHENRAEHIGRVLGEVAPSMLLTSSSESIAFGI 788
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHA 368
G+ SMPA R FSM+AA+AV +DF+LQ+T FVA++ LDS R E R + F C
Sbjct: 789 GAMSSMPAVRAFSMYAAVAVAMDFLLQITCFVAMMALDSSRQEANRYEIFCCA------T 842
Query: 369 DPDKGIRQRKPG 404
D + G + ++PG
Sbjct: 843 DKEAGKQPKEPG 854
[57][TOP]
>UniRef100_B7Q350 Niemann-Pick type C1 domain-containing protein, putative n=1
Tax=Ixodes scapularis RepID=B7Q350_IXOSC
Length = 1626
Score = 104 bits (260), Expect = 3e-21
Identities = 55/112 (49%), Positives = 78/112 (69%), Gaps = 2/112 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL--ELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV +R + E PL+ ++S + +GPS+ LAS+SE F +G
Sbjct: 620 IPFLVLAVGVDNIFILVQGFQRANVLDEEPLDQKVSRVVGNLGPSLMLASVSEAACFLLG 679
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCI 347
+MPA R F+++A +A+LLDF+LQVT FVAL+ LD++R +R+D CI
Sbjct: 680 GLSTMPAVRTFALYAGVALLLDFLLQVTCFVALLTLDAKRQRARRLDMCCCI 731
[58][TOP]
>UniRef100_B6HDY6 Pc20g15300 protein n=1 Tax=Penicillium chrysogenum Wisconsin 54-1255
RepID=B6HDY6_PENCW
Length = 1275
Score = 104 bits (260), Expect = 3e-21
Identities = 51/115 (44%), Positives = 80/115 (69%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH +R + P ++ R++ A+ +GPSI L++L+E +AFA+
Sbjct: 675 IPFLVLAVGVDNIFLIVHEFERVNISHPDEEIDERVARAVSRIGPSIFLSALTETVAFAL 734
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
G F+ MPA R F+ +AA AV ++ VLQ T F++++ L+ +R + R DC PC+ V
Sbjct: 735 GVFVGMPAVRNFAAYAAGAVFINAVLQTTMFISVLALNQKRVQSLRADCVPCLTV 789
[59][TOP]
>UniRef100_Q5KGS9 Vacuolar membrane protein, putative n=1 Tax=Filobasidiella neoformans
RepID=Q5KGS9_CRYNE
Length = 1330
Score = 104 bits (259), Expect = 4e-21
Identities = 57/135 (42%), Positives = 84/135 (62%), Gaps = 23/135 (17%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQP-----------------------LELPLEGRISNAL 128
IPFLVLA GVDN+ ILVH ++RQ L E R++ A+
Sbjct: 698 IPFLVLAVGVDNVFILVHELERQNNLHAAQQPGDDESVHSNGAQPSGTFLAPEERVARAV 757
Query: 129 VEVGPSITLASLSEVLAFAVGSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQ 308
+GPSI L+S++EV+AFA+G+ + MPA R F+++AA +VL ++Q T FV+ + LD +
Sbjct: 758 ARMGPSIMLSSVTEVVAFALGALVPMPAVRNFAIYAAGSVLFGAIMQCTVFVSAMTLDLR 817
Query: 309 RAEDKRVDCFPCIKV 353
R+E R+DCFPCI++
Sbjct: 818 RSESMRIDCFPCIRL 832
[60][TOP]
>UniRef100_Q55SD4 Putative uncharacterized protein n=1 Tax=Filobasidiella neoformans
RepID=Q55SD4_CRYNE
Length = 1330
Score = 104 bits (259), Expect = 4e-21
Identities = 57/135 (42%), Positives = 84/135 (62%), Gaps = 23/135 (17%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQP-----------------------LELPLEGRISNAL 128
IPFLVLA GVDN+ ILVH ++RQ L E R++ A+
Sbjct: 698 IPFLVLAVGVDNVFILVHELERQNNLHAAQQPGDDESVHSNGAQPSGTFLAPEERVARAV 757
Query: 129 VEVGPSITLASLSEVLAFAVGSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQ 308
+GPSI L+S++EV+AFA+G+ + MPA R F+++AA +VL ++Q T FV+ + LD +
Sbjct: 758 ARMGPSIMLSSVTEVVAFALGALVPMPAVRNFAIYAAGSVLFGAIMQCTVFVSAMTLDLR 817
Query: 309 RAEDKRVDCFPCIKV 353
R+E R+DCFPCI++
Sbjct: 818 RSESMRIDCFPCIRL 832
[61][TOP]
>UniRef100_C6HD90 Patched sphingolipid transporter n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6HD90_AJECH
Length = 1061
Score = 104 bits (259), Expect = 4e-21
Identities = 54/125 (43%), Positives = 84/125 (67%), Gaps = 3/125 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH +R P ++ RI+ +L +GPSI L++ +E +AFA+
Sbjct: 499 IPFLVLAIGVDNIFLIVHEFERVNGNHPDEEIDERIARSLGRMGPSILLSATTETIAFAM 558
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHA 368
G+F+ MPA + F+ +AA AVL++ +LQVT FV+++ L+ +R E R DC PC+ V ++
Sbjct: 559 GAFVGMPAVKNFAAYAAGAVLINALLQVTMFVSVLALNQRRVESLRADCLPCLTVRKANS 618
Query: 369 DPDKG 383
G
Sbjct: 619 SSIPG 623
[62][TOP]
>UniRef100_A6RA01 Putative uncharacterized protein n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RA01_AJECN
Length = 1181
Score = 104 bits (259), Expect = 4e-21
Identities = 54/125 (43%), Positives = 84/125 (67%), Gaps = 3/125 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH +R P ++ RI+ +L +GPSI L++ +E +AFA+
Sbjct: 581 IPFLVLAIGVDNIFLIVHEFERVNGNHPDEEIDERIARSLGRMGPSILLSATTETIAFAM 640
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHA 368
G+F+ MPA + F+ +AA AVL++ +LQVT FV+++ L+ +R E R DC PC+ V ++
Sbjct: 641 GAFVGMPAVKNFAAYAAGAVLINALLQVTMFVSVLALNQRRVESLRADCLPCLTVRKANS 700
Query: 369 DPDKG 383
G
Sbjct: 701 SSIPG 705
[63][TOP]
>UniRef100_A7S0G1 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
RepID=A7S0G1_NEMVE
Length = 1277
Score = 103 bits (258), Expect = 5e-21
Identities = 58/113 (51%), Positives = 78/113 (69%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN I+V A +R + P+ +IS AL EV PS+ L+SLSE +AF G
Sbjct: 682 IPFLVLAVGVDNFFIMVQAYQRINRYSNEPVSKKISCALGEVAPSMLLSSLSESVAFGFG 741
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ MPA +VFS++A+ AV +DF+LQ+T FVAL+ LD++R E R D C+K
Sbjct: 742 AMSDMPAVKVFSLYASFAVAVDFILQITWFVALMSLDAKRQETNRWDIMCCVK 794
[64][TOP]
>UniRef100_C5JHY3 Patched sphingolipid transporter n=1 Tax=Ajellomyces dermatitidis
SLH14081 RepID=C5JHY3_AJEDS
Length = 1274
Score = 103 bits (258), Expect = 5e-21
Identities = 54/125 (43%), Positives = 83/125 (66%), Gaps = 3/125 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH +R P ++ RI+ AL +GPSI L++ +E +AFA+
Sbjct: 674 IPFLVLAIGVDNIFLIVHEFERVNGSHPDEEIDERIARALGRMGPSILLSATTETIAFAM 733
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHA 368
G+F+ MPA + F+ +AA AV ++ +LQVT FV+++ L+ +R E R DC PC+ V ++
Sbjct: 734 GAFVGMPAVKNFAAYAAGAVFINALLQVTMFVSVLALNQRRVESLRADCLPCLTVRKANS 793
Query: 369 DPDKG 383
G
Sbjct: 794 SSIPG 798
[65][TOP]
>UniRef100_C5GGT7 Patched sphingolipid transporter n=1 Tax=Ajellomyces dermatitidis
ER-3 RepID=C5GGT7_AJEDR
Length = 1274
Score = 103 bits (258), Expect = 5e-21
Identities = 54/125 (43%), Positives = 83/125 (66%), Gaps = 3/125 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH +R P ++ RI+ AL +GPSI L++ +E +AFA+
Sbjct: 674 IPFLVLAIGVDNIFLIVHEFERVNGSHPDEEIDERIARALGRMGPSILLSATTETIAFAM 733
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHA 368
G+F+ MPA + F+ +AA AV ++ +LQVT FV+++ L+ +R E R DC PC+ V ++
Sbjct: 734 GAFVGMPAVKNFAAYAAGAVFINALLQVTMFVSVLALNQRRVESLRADCLPCLTVRKANS 793
Query: 369 DPDKG 383
G
Sbjct: 794 SSIPG 798
[66][TOP]
>UniRef100_A1CTG5 Patched sphingolipid transporter (Ncr1), putative n=1 Tax=Aspergillus
clavatus RepID=A1CTG5_ASPCL
Length = 1274
Score = 103 bits (258), Expect = 5e-21
Identities = 50/115 (43%), Positives = 82/115 (71%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH +R + P ++ R++ A+ +GPSI L++++E +AFA+
Sbjct: 673 IPFLVLAVGVDNIFLVVHEFERINVSHPDEEIDERVARAVGRIGPSIFLSAVTETVAFAL 732
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
G F+ MPA + F+++AA AV ++ +LQ+T FV+++ L+ +R E R DC PC+ V
Sbjct: 733 GVFVGMPAVKNFAVYAAGAVFINAILQMTMFVSVLALNQRRVESLRADCMPCVTV 787
[67][TOP]
>UniRef100_Q16VL3 Niemann-pick C1 n=1 Tax=Aedes aegypti RepID=Q16VL3_AEDAE
Length = 1266
Score = 103 bits (257), Expect = 6e-21
Identities = 56/113 (49%), Positives = 75/113 (66%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR-QPLELP-LEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ +LVHA +R ++ P + I AL ++GPSI L S SE FA+G
Sbjct: 678 IPFLVLAVGVDNIFMLVHAFQRIDRVQTPETDKAIGKALGQIGPSILLTSASECCCFAIG 737
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
MPA F+ +A +A+ +DFVLQ+TAFVAL+ LD +R R+D F C+K
Sbjct: 738 GLSPMPAVNTFAWYATVALFVDFVLQITAFVALMALDERRVASGRLDLFCCVK 790
[68][TOP]
>UniRef100_UPI0000E7FEDB PREDICTED: similar to Niemann-Pick C1 n=1 Tax=Gallus gallus
RepID=UPI0000E7FEDB
Length = 1261
Score = 103 bits (256), Expect = 8e-21
Identities = 58/113 (51%), Positives = 80/113 (70%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR-QPLE-LPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ I+V ++R + LE L+ +I L +V PS+ L+S SE +AF +G
Sbjct: 674 IPFLVLAIGVDNLFIIVQTLQRDERLEGETLDKQIGRVLGDVAPSMFLSSFSETVAFFLG 733
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ +MPA R FS+FA +AVL+DF+LQVT FV+L+ LD +R E R+D CIK
Sbjct: 734 TLSTMPAVRTFSLFAGMAVLIDFILQVTCFVSLLGLDIRRQERNRLDILCCIK 786
[69][TOP]
>UniRef100_UPI000060FC24 Niemann-Pick C1 protein precursor. n=1 Tax=Gallus gallus
RepID=UPI000060FC24
Length = 1278
Score = 103 bits (256), Expect = 8e-21
Identities = 58/113 (51%), Positives = 80/113 (70%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR-QPLE-LPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ I+V ++R + LE L+ +I L +V PS+ L+S SE +AF +G
Sbjct: 691 IPFLVLAIGVDNLFIIVQTLQRDERLEGETLDKQIGRVLGDVAPSMFLSSFSETVAFFLG 750
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ +MPA R FS+FA +AVL+DF+LQVT FV+L+ LD +R E R+D CIK
Sbjct: 751 TLSTMPAVRTFSLFAGMAVLIDFILQVTCFVSLLGLDIRRQERNRLDILCCIK 803
[70][TOP]
>UniRef100_A8NWN7 Putative uncharacterized protein n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NWN7_COPC7
Length = 1382
Score = 103 bits (256), Expect = 8e-21
Identities = 57/157 (36%), Positives = 86/157 (54%), Gaps = 43/157 (27%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQ------------------------------------- 86
IPFLVLA GVDN+ +LV+ + RQ
Sbjct: 729 IPFLVLAVGVDNVFLLVNELDRQNLLHGPTAAFSGPSGPSLLSPTSPTQSRNPYEYSAED 788
Query: 87 ------PLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFISMPACRVFSMFAALAV 248
P+ LP E R++ L ++GPSI L++++E AFA+G+ + MPA R F+++AA +V
Sbjct: 789 IDASSMPIHLPAEERVARTLAKMGPSILLSTITETTAFALGALVPMPAVRNFALYAAGSV 848
Query: 249 LLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHS 359
L+ +LQVT F++ + LD +R E RVDCFPC+++ S
Sbjct: 849 FLNALLQVTVFISALTLDLRRTESNRVDCFPCVRLSS 885
[71][TOP]
>UniRef100_UPI00017B0961 UPI00017B0961 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B0961
Length = 1266
Score = 102 bits (255), Expect = 1e-20
Identities = 55/115 (47%), Positives = 79/115 (68%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ I+V ++R +P L +I L +V PS+ L+S SE +AF +
Sbjct: 686 IPFLVLAVGVDNIFIIVQTLQRDE-RMPHEELHQQIGRILGDVAPSMFLSSFSETVAFFL 744
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
G+ +MPA R FS+FA LAV +DF+LQ++ FV+L+ LD+ R ED R+D C+K+
Sbjct: 745 GALSNMPAARTFSLFAGLAVFIDFLLQISCFVSLLGLDASRQEDNRLDIVCCVKL 799
[72][TOP]
>UniRef100_B4L379 GI15499 n=1 Tax=Drosophila mojavensis RepID=B4L379_DROMO
Length = 1217
Score = 102 bits (255), Expect = 1e-20
Identities = 53/113 (46%), Positives = 75/113 (66%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ I+VH +R I A+ +VGPSI + SE FA+G
Sbjct: 646 IPFLVLAVGVDNIFIMVHTYERLDHTQFASTHEAIGEAIGQVGPSILQTACSEFACFAIG 705
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ MPA + F+M+AA+A+LLDF+LQ+TAFVAL+ +D +R + R+D F C++
Sbjct: 706 AISEMPAVKTFAMYAAIAILLDFLLQITAFVALMAIDERRRKSGRLDLFCCVR 758
[73][TOP]
>UniRef100_A0CA55 Chromosome undetermined scaffold_160, whole genome shotgun sequence
n=1 Tax=Paramecium tetraurelia RepID=A0CA55_PARTE
Length = 903
Score = 102 bits (255), Expect = 1e-20
Identities = 58/129 (44%), Positives = 81/129 (62%)
Frame = +3
Query: 6 SLWNIPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFA 185
SL IPFL+LA GVDNM I+ H K+Q E R+ + L +VGPSIT+A++ E LAF
Sbjct: 344 SLEVIPFLILAIGVDNMFIITHNYKKQKHPTVPE-RMGHTLKQVGPSITIAAICETLAFL 402
Query: 186 VGSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFH 365
VGS MPA + F + AA+ V +D++LQ+T FVA + LD QR + KR D C + ++
Sbjct: 403 VGSLTKMPALQSFCIQAAVGVFIDYLLQITMFVAFLTLDEQRKKHKRYDLMICKQDPNYA 462
Query: 366 ADPDKGIRQ 392
D+ + Q
Sbjct: 463 IKEDRKLIQ 471
[74][TOP]
>UniRef100_UPI000194BC77 PREDICTED: similar to Niemann-Pick C1 n=1 Tax=Taeniopygia guttata
RepID=UPI000194BC77
Length = 1280
Score = 102 bits (254), Expect = 1e-20
Identities = 56/113 (49%), Positives = 77/113 (68%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ I+V ++R L+ +I L +V PS+ L+S SE +AF +G
Sbjct: 693 IPFLVLAIGVDNIFIMVQTLQRDERLQGETLDKQIGRVLGDVAPSMFLSSFSETVAFFLG 752
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ +MPA R FS+FA +AVL+DF+LQVT FV+L+ LD +R E R+D CIK
Sbjct: 753 TLSTMPAVRTFSLFAGMAVLIDFILQVTCFVSLLGLDIKRQESNRLDVLCCIK 805
[75][TOP]
>UniRef100_A0CEP2 Chromosome undetermined scaffold_172, whole genome shotgun sequence
n=1 Tax=Paramecium tetraurelia RepID=A0CEP2_PARTE
Length = 912
Score = 102 bits (254), Expect = 1e-20
Identities = 58/129 (44%), Positives = 80/129 (62%)
Frame = +3
Query: 6 SLWNIPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFA 185
SL IPFL+LA GVDNM I+ H K+Q E R+ L +VGPSIT+A++ E LAF
Sbjct: 351 SLEVIPFLILAIGVDNMFIITHNYKKQKHPTVPE-RMGQTLKQVGPSITIAAICETLAFL 409
Query: 186 VGSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFH 365
VGS MPA + F + AA+ V +D++LQ+T FVA + LD QR + KR D C + ++
Sbjct: 410 VGSLTKMPALQSFCIQAAVGVFIDYLLQITMFVAFLTLDEQRKKHKRYDLMICKQDPNYA 469
Query: 366 ADPDKGIRQ 392
D+ + Q
Sbjct: 470 IKEDRKLIQ 478
[76][TOP]
>UniRef100_UPI000186F3A4 Niemann-Pick C1 protein precursor, putative n=1 Tax=Pediculus humanus
corporis RepID=UPI000186F3A4
Length = 1233
Score = 101 bits (252), Expect = 2e-20
Identities = 53/115 (46%), Positives = 77/115 (66%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAV---KRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFL+LA GVDN+ ILVH K +E I AL +VGPSI L+SLSE F++
Sbjct: 668 IPFLILAVGVDNIFILVHTYQKCKSYGKNATVEQDIGKALGKVGPSILLSSLSEAACFSI 727
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
G+ +MPA + F+ ++++A++L+F+LQ+T FV+++ LDS+R D F CIKV
Sbjct: 728 GTLSNMPAIKTFAQYSSVAIILNFLLQITCFVSILSLDSKRERKNYADVFCCIKV 782
[77][TOP]
>UniRef100_UPI0001758613 PREDICTED: similar to NPC1 protein n=1 Tax=Tribolium castaneum
RepID=UPI0001758613
Length = 1112
Score = 101 bits (252), Expect = 2e-20
Identities = 55/125 (44%), Positives = 78/125 (62%), Gaps = 2/125 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL--ELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ I+V +R+ L +L LE I + +VGPS+ L S SE+ FA+G
Sbjct: 538 IPFLVLAVGVDNIFIIVQTHQRKQLNEKLSLEEEIGETMAKVGPSMLLTSCSEIFCFAIG 597
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHAD 371
+ +MPA F+++A A+ +F+LQ+TAFVAL LD +R R++ F C K + D
Sbjct: 598 ALSTMPAVNTFAIYATFAIFFNFLLQITAFVALFTLDLKRYRANRMEIFFCEKAKTSPED 657
Query: 372 PDKGI 386
GI
Sbjct: 658 IGPGI 662
[78][TOP]
>UniRef100_UPI00003BD942 hypothetical protein DEHA0D05335g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BD942
Length = 1264
Score = 101 bits (252), Expect = 2e-20
Identities = 48/115 (41%), Positives = 78/115 (67%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFL+LA G+DN+ ++VH + LP +E RIS L VGPS ++++ + F +
Sbjct: 659 IPFLILAVGIDNIFLIVHELHLNNKLLPDDSIEYRISQTLKNVGPSCLISAILQFAMFLL 718
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
+ + MPA + F+ ++A A++++F+LQ+T F+AL+ LD +R ED R+DC PCI+V
Sbjct: 719 ATRVEMPAVKNFAFYSAGAIMMNFILQMTGFIALLALDQRRLEDDRIDCVPCIQV 773
[79][TOP]
>UniRef100_A0BF69 Chromosome undetermined scaffold_103, whole genome shotgun sequence
n=1 Tax=Paramecium tetraurelia RepID=A0BF69_PARTE
Length = 912
Score = 101 bits (252), Expect = 2e-20
Identities = 54/113 (47%), Positives = 73/113 (64%)
Frame = +3
Query: 6 SLWNIPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFA 185
SL IPFL+LA GVDNM I+ H K+Q ++ R+ N L +VGPSIT+A++ E LAF
Sbjct: 351 SLEVIPFLILAIGVDNMFIITHQFKKQK-HPTIQERMGNTLEQVGPSITIAAICETLAFL 409
Query: 186 VGSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
VGS MPA + F + AA+ V +D+ LQ+T FVA + D +R + KR D C
Sbjct: 410 VGSMTKMPALQSFCIQAAVGVFIDYFLQITMFVAFLTWDEERKKHKRYDLIVC 462
[80][TOP]
>UniRef100_Q6BT03 DEHA2D04620p n=1 Tax=Debaryomyces hansenii RepID=Q6BT03_DEBHA
Length = 1264
Score = 101 bits (252), Expect = 2e-20
Identities = 48/115 (41%), Positives = 78/115 (67%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFL+LA G+DN+ ++VH + LP +E RIS L VGPS ++++ + F +
Sbjct: 659 IPFLILAVGIDNIFLIVHELHLNNKLLPDDSIEYRISQTLKNVGPSCLISAILQFAMFLL 718
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
+ + MPA + F+ ++A A++++F+LQ+T F+AL+ LD +R ED R+DC PCI+V
Sbjct: 719 ATRVEMPAVKNFAFYSAGAIMMNFILQMTGFIALLALDQRRLEDDRIDCVPCIQV 773
[81][TOP]
>UniRef100_C4QWB0 Vacuolar membrane protein that transits through the biosynthetic
vacuolar protein sorting pathway n=1 Tax=Pichia pastoris
GS115 RepID=C4QWB0_PICPG
Length = 1284
Score = 101 bits (252), Expect = 2e-20
Identities = 53/115 (46%), Positives = 76/115 (66%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEG---RISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++ H + + E R+S A+ ++GPSI L+S S+V FA+
Sbjct: 664 IPFLVLAIGVDNIFLISHELNTVNMNYSTESIPLRVSKAMGKIGPSILLSSSSQVFCFAL 723
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
+ +SMPA R F+ + +AVL + +LQ TAFV+L+ LD R ED R+D FP +KV
Sbjct: 724 ATVVSMPAVRNFAAYCTMAVLFNCILQTTAFVSLLTLDQIRLEDNRLDVFPFVKV 778
[82][TOP]
>UniRef100_UPI00015B5F3E PREDICTED: similar to CG5722-PA n=1 Tax=Nasonia vitripennis
RepID=UPI00015B5F3E
Length = 1253
Score = 101 bits (251), Expect = 3e-20
Identities = 53/114 (46%), Positives = 73/114 (64%), Gaps = 2/114 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV A +R P + + + VGPS+ L S SEVL F++G
Sbjct: 681 IPFLVLAIGVDNIFILVRAHQRHPRREGESIPEHVGRIVGSVGPSLLLTSTSEVLCFSIG 740
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
+ MPA F+ FAAL++ L+F LQ++AFV+L+ LD+ R E R+DC C +
Sbjct: 741 TLSDMPAVNTFAKFAALSICLNFFLQISAFVSLLSLDAARQEQNRIDCLCCFAI 794
[83][TOP]
>UniRef100_UPI00016E624E UPI00016E624E related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E624E
Length = 1264
Score = 101 bits (251), Expect = 3e-20
Identities = 56/123 (45%), Positives = 79/123 (64%), Gaps = 3/123 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEG---RISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ILV ++R +P E +I L +V PS+ L+S SE +AF +
Sbjct: 685 IPFLVLAVGVDNIFILVQTLQRDE-RMPQEEIHHQIGRILGDVAPSMFLSSFSETVAFFL 743
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHA 368
G+ +MPA R FS+FA LAV +DF+LQ++ FV+L+ LD+ R E R+D C+K+
Sbjct: 744 GALSNMPAVRTFSLFAGLAVFIDFLLQISCFVSLLGLDASRQEGNRMDIVCCVKIQGEEV 803
Query: 369 DPD 377
D
Sbjct: 804 KKD 806
[84][TOP]
>UniRef100_UPI0000F2C55D PREDICTED: similar to Niemann-Pick C disease protein n=1
Tax=Monodelphis domestica RepID=UPI0000F2C55D
Length = 1280
Score = 100 bits (249), Expect = 5e-20
Identities = 54/121 (44%), Positives = 77/121 (63%), Gaps = 2/121 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV +R L+ ++ L EV PS+ L+S SE +AF +G
Sbjct: 693 IPFLVLAVGVDNIFILVQTFQRDERLQGETLDKQLGRILGEVAPSMLLSSFSEAIAFFLG 752
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHAD 371
+ +MPA R FS+FA +AV +DF+LQ+T FV+L+ LD +R E ++D C+K+
Sbjct: 753 ALSTMPAVRTFSLFAGMAVFIDFLLQITCFVSLLGLDIKRQEKNKLDILCCVKIAEDRTG 812
Query: 372 P 374
P
Sbjct: 813 P 813
[85][TOP]
>UniRef100_Q9VRC9 NPC1b n=1 Tax=Drosophila melanogaster RepID=Q9VRC9_DROME
Length = 1254
Score = 100 bits (249), Expect = 5e-20
Identities = 54/113 (47%), Positives = 74/113 (65%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ I+VH +R I A+ +VGPSI + SE+ FA+G
Sbjct: 662 IPFLVLAVGVDNIFIMVHTYQRLDHSKFKTTHEAIGEAIGQVGPSILQTAGSEMACFAIG 721
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
MPA + F+M+AA+A+LLDF+LQ+TAFVAL+ +D +R D R+D C+K
Sbjct: 722 CISDMPAVKTFAMYAAIAILLDFLLQITAFVALMAIDEKRYLDGRLDMLCCVK 774
[86][TOP]
>UniRef100_B4I6C1 GM23054 n=1 Tax=Drosophila sechellia RepID=B4I6C1_DROSE
Length = 1228
Score = 100 bits (249), Expect = 5e-20
Identities = 55/129 (42%), Positives = 80/129 (62%), Gaps = 2/129 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ I+VH +R I A+ +VGPSI + SE+ FA+G
Sbjct: 659 IPFLVLAVGVDNIFIMVHTYQRLDHSKFKTTHEAIGEAIGQVGPSILQTAGSEMACFAIG 718
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHAD 371
MPA + F+M+AA+A+LLDF+LQ+TAFVAL+ +D +R D R+D C++ +
Sbjct: 719 CISDMPAVKTFAMYAAIAILLDFLLQITAFVALMAIDERRYLDGRLDMLCCVRSGGKKIN 778
Query: 372 PDKGIRQRK 398
+ G+ + K
Sbjct: 779 DEDGVDRPK 787
[87][TOP]
>UniRef100_B9WA46 Sterol homeostasis regulator, putative n=1 Tax=Candida dubliniensis
CD36 RepID=B9WA46_CANDC
Length = 1240
Score = 100 bits (249), Expect = 5e-20
Identities = 51/123 (41%), Positives = 79/123 (64%), Gaps = 3/123 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVH---AVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA G+DN+ ++VH + +L LE RIS+AL +GPS ++++ +V F +
Sbjct: 639 IPFLVLAIGIDNIFLIVHELHVISEGNPDLALEARISHALKNIGPSCFISAVLQVCMFLL 698
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHA 368
+ + MPA + F+ + A AVL++F+LQ+T F+ L+ LD +R ED RVDC P I +
Sbjct: 699 ATTVGMPAVKNFAYYGAGAVLINFLLQMTCFIGLLALDQRRLEDNRVDCVPWITIPPIQI 758
Query: 369 DPD 377
+ D
Sbjct: 759 NGD 761
[88][TOP]
>UniRef100_UPI0000E24CB6 PREDICTED: Niemann-Pick disease, type C1 isoform 5 n=1 Tax=Pan
troglodytes RepID=UPI0000E24CB6
Length = 1217
Score = 100 bits (248), Expect = 7e-20
Identities = 55/113 (48%), Positives = 75/113 (66%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV A +R L+ ++ L EV PS+ L+S SE +AF +G
Sbjct: 690 IPFLVLAVGVDNIFILVQAYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLG 749
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ MPA FS+FA LAV +DF+LQ+T FV+L+ LD +R E R+D F C++
Sbjct: 750 ALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCVR 802
[89][TOP]
>UniRef100_UPI0000E24CB5 PREDICTED: Niemann-Pick disease, type C1 isoform 2 n=1 Tax=Pan
troglodytes RepID=UPI0000E24CB5
Length = 1261
Score = 100 bits (248), Expect = 7e-20
Identities = 55/113 (48%), Positives = 75/113 (66%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV A +R L+ ++ L EV PS+ L+S SE +AF +G
Sbjct: 690 IPFLVLAVGVDNIFILVQAYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLG 749
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ MPA FS+FA LAV +DF+LQ+T FV+L+ LD +R E R+D F C++
Sbjct: 750 ALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCVR 802
[90][TOP]
>UniRef100_UPI0000E24CB3 PREDICTED: Niemann-Pick disease, type C1 isoform 1 n=1 Tax=Pan
troglodytes RepID=UPI0000E24CB3
Length = 1285
Score = 100 bits (248), Expect = 7e-20
Identities = 55/113 (48%), Positives = 75/113 (66%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV A +R L+ ++ L EV PS+ L+S SE +AF +G
Sbjct: 690 IPFLVLAVGVDNIFILVQAYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLG 749
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ MPA FS+FA LAV +DF+LQ+T FV+L+ LD +R E R+D F C++
Sbjct: 750 ALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCVR 802
[91][TOP]
>UniRef100_UPI000036A3B7 PREDICTED: Niemann-Pick disease, type C1 isoform 4 n=2 Tax=Pan
troglodytes RepID=UPI000036A3B7
Length = 1277
Score = 100 bits (248), Expect = 7e-20
Identities = 55/113 (48%), Positives = 75/113 (66%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV A +R L+ ++ L EV PS+ L+S SE +AF +G
Sbjct: 690 IPFLVLAVGVDNIFILVQAYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLG 749
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ MPA FS+FA LAV +DF+LQ+T FV+L+ LD +R E R+D F C++
Sbjct: 750 ALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCVR 802
[92][TOP]
>UniRef100_UPI0001A2D25E hypothetical protein LOC553611 n=1 Tax=Danio rerio
RepID=UPI0001A2D25E
Length = 1076
Score = 100 bits (248), Expect = 7e-20
Identities = 54/124 (43%), Positives = 79/124 (63%), Gaps = 2/124 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL--ELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ I+V +R E L +I L +V PS+ L+S SE +AF +G
Sbjct: 674 IPFLVLAVGVDNIFIIVQTYQRDERMPEEELHQQIGRILGDVAPSMFLSSFSETVAFFLG 733
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHAD 371
+ +MPA R FS+FA LA+ +DF+LQ++ FV+L+ LD +R E R+D C+K+ +
Sbjct: 734 ALSTMPAVRTFSLFAGLAIFIDFLLQISCFVSLLGLDIKRQEANRMDILCCVKLSDGQEE 793
Query: 372 PDKG 383
+G
Sbjct: 794 KSEG 797
[93][TOP]
>UniRef100_Q29GK5 GA11389 n=1 Tax=Drosophila pseudoobscura pseudoobscura
RepID=Q29GK5_DROPS
Length = 1248
Score = 100 bits (248), Expect = 7e-20
Identities = 56/129 (43%), Positives = 79/129 (61%), Gaps = 3/129 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR---QPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ I+VH +R E E I A+ +VGPSI + SE FA+
Sbjct: 667 IPFLVLAVGVDNIFIMVHTFQRLDHSRFETTHEA-IGEAIGQVGPSILQTAGSEFACFAI 725
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHA 368
G+ MPA + F+M+AA A+L DF+LQ+TAFVAL+ +D +R D R+D C++
Sbjct: 726 GALSDMPAVKTFAMYAAAAILFDFLLQITAFVALMAIDQRRVLDGRLDMLCCVQTKKKPE 785
Query: 369 DPDKGIRQR 395
D G+ ++
Sbjct: 786 PQDVGLLEK 794
[94][TOP]
>UniRef100_B4M3Q5 GJ19256 n=1 Tax=Drosophila virilis RepID=B4M3Q5_DROVI
Length = 1254
Score = 100 bits (248), Expect = 7e-20
Identities = 53/113 (46%), Positives = 74/113 (65%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ I+VH +R I A+ +VGPSI + SE FA+G
Sbjct: 663 IPFLVLAVGVDNIFIMVHTYQRLDHSRYPSTHEAIGEAIGQVGPSILQTASSEFACFAIG 722
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ MPA + F+M+AA+A+LLDF+LQ+TAFVAL+ +D +R D R+D C++
Sbjct: 723 AISEMPAVKTFAMYAAIAILLDFLLQITAFVALMAIDERRYLDGRLDMLCCVR 775
[95][TOP]
>UniRef100_B4JXM3 GH17745 n=1 Tax=Drosophila grimshawi RepID=B4JXM3_DROGR
Length = 1246
Score = 100 bits (248), Expect = 7e-20
Identities = 51/115 (44%), Positives = 77/115 (66%), Gaps = 2/115 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFLVLA GVDN+ I+VH+ +R + I A+ +V PSI + SE FA+G
Sbjct: 663 LPFLVLAVGVDNIFIMVHSYQRLDRSRYATTHEAIGEAVGQVAPSILQTASSEFACFAIG 722
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVH 356
+ MPA + F+M+AA+A++LDF+LQ+TAFVAL+ +D +R ED R+D C++ +
Sbjct: 723 AICDMPAVKTFAMYAAMAIVLDFLLQITAFVALMAIDERRHEDGRLDMLCCMRTN 777
[96][TOP]
>UniRef100_Q59GR1 Niemann-Pick disease, type C1 variant (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GR1_HUMAN
Length = 1289
Score = 100 bits (248), Expect = 7e-20
Identities = 55/113 (48%), Positives = 75/113 (66%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV A +R L+ ++ L EV PS+ L+S SE +AF +G
Sbjct: 701 IPFLVLAVGVDNIFILVQAYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLG 760
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ MPA FS+FA LAV +DF+LQ+T FV+L+ LD +R E R+D F C++
Sbjct: 761 ALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCVR 813
[97][TOP]
>UniRef100_B4DIP7 cDNA FLJ57114, highly similar to Niemann-Pick C1 protein n=1
Tax=Homo sapiens RepID=B4DIP7_HUMAN
Length = 776
Score = 100 bits (248), Expect = 7e-20
Identities = 55/113 (48%), Positives = 75/113 (66%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV A +R L+ ++ L EV PS+ L+S SE +AF +G
Sbjct: 535 IPFLVLAVGVDNIFILVQAYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLG 594
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ MPA FS+FA LAV +DF+LQ+T FV+L+ LD +R E R+D F C++
Sbjct: 595 ALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCVR 647
[98][TOP]
>UniRef100_B4DET3 cDNA FLJ51802, highly similar to Niemann-Pick C1 protein n=1
Tax=Homo sapiens RepID=B4DET3_HUMAN
Length = 960
Score = 100 bits (248), Expect = 7e-20
Identities = 55/113 (48%), Positives = 75/113 (66%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV A +R L+ ++ L EV PS+ L+S SE +AF +G
Sbjct: 372 IPFLVLAVGVDNIFILVQAYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLG 431
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ MPA FS+FA LAV +DF+LQ+T FV+L+ LD +R E R+D F C++
Sbjct: 432 ALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCVR 484
[99][TOP]
>UniRef100_O15118 Niemann-Pick C1 protein n=1 Tax=Homo sapiens RepID=NPC1_HUMAN
Length = 1278
Score = 100 bits (248), Expect = 7e-20
Identities = 55/113 (48%), Positives = 75/113 (66%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV A +R L+ ++ L EV PS+ L+S SE +AF +G
Sbjct: 690 IPFLVLAVGVDNIFILVQAYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLG 749
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ MPA FS+FA LAV +DF+LQ+T FV+L+ LD +R E R+D F C++
Sbjct: 750 ALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCVR 802
[100][TOP]
>UniRef100_B4R3B8 GD17503 n=1 Tax=Drosophila simulans RepID=B4R3B8_DROSI
Length = 1083
Score = 99.4 bits (246), Expect = 1e-19
Identities = 53/113 (46%), Positives = 74/113 (65%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ I+VH +R I A+ +VGPSI + SE+ FA+G
Sbjct: 662 IPFLVLAVGVDNIFIMVHTYQRLDHSKFKTTHEAIGEAIGQVGPSILQTAGSEMACFAIG 721
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
MPA + F+M+AA+A+LLDF+LQ+TAFVAL+ +D +R D R+D C++
Sbjct: 722 CISDMPAVKTFAMYAAIAILLDFLLQITAFVALMAIDERRYLDGRLDMLCCVR 774
[101][TOP]
>UniRef100_B3NY50 GG19701 n=1 Tax=Drosophila erecta RepID=B3NY50_DROER
Length = 1248
Score = 99.4 bits (246), Expect = 1e-19
Identities = 53/113 (46%), Positives = 74/113 (65%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ I+VH +R I A+ +VGPSI + SE+ FA+G
Sbjct: 661 IPFLVLAVGVDNIFIMVHTYQRLDHSKFKTTHEAIGEAIGQVGPSILQTAGSEMACFAIG 720
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
MPA + F+M+AA+A+LLDF+LQ+TAFVAL+ +D +R D R+D C++
Sbjct: 721 CISDMPAVKTFAMYAAIAILLDFLLQITAFVALMAIDEKRYLDGRLDMLCCVR 773
[102][TOP]
>UniRef100_C7Z5H5 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z5H5_NECH7
Length = 1272
Score = 99.4 bits (246), Expect = 1e-19
Identities = 50/115 (43%), Positives = 81/115 (70%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPF+VLA GVDN+ ++VH ++R + P +E R++ AL +GPSI ++L+E +AFA+
Sbjct: 664 IPFIVLAVGVDNIFLIVHELERVNVSCPDQMVEERVARALGRMGPSILFSALTETVAFAL 723
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
G+ + MPA R F+ +AA AVL++ +LQ+T FV+ + L+ R ED R + +PC ++
Sbjct: 724 GTAVGMPAVRNFAAYAAGAVLVNALLQMTMFVSFLSLNQMRVEDHRCELWPCWQI 778
[103][TOP]
>UniRef100_A3GGU6 Predicted protein n=1 Tax=Pichia stipitis RepID=A3GGU6_PICST
Length = 1268
Score = 99.4 bits (246), Expect = 1e-19
Identities = 52/132 (39%), Positives = 87/132 (65%), Gaps = 9/132 (6%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVH---AVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA G+DN+ ++VH V ++ +E RI+ AL +GPS ++++ +V F +
Sbjct: 644 IPFLVLAIGIDNIFLIVHELHVVSETLYDMSIELRIAQALRNIGPSCLISAVLQVSMFFL 703
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV---HS 359
+ + MPA + F+ ++A+AVL++F+LQ+T F++L+ LD R E+ R+DCFP I + H+
Sbjct: 704 ATNVDMPAVKNFAYYSAVAVLINFLLQMTMFISLLALDQHRLENNRLDCFPWITIEDQHN 763
Query: 360 FH---ADPDKGI 386
H DP++ I
Sbjct: 764 IHLPEGDPNEEI 775
[104][TOP]
>UniRef100_Q23E28 Patched family protein n=1 Tax=Tetrahymena thermophila SB210
RepID=Q23E28_TETTH
Length = 1207
Score = 99.0 bits (245), Expect = 1e-19
Identities = 55/111 (49%), Positives = 74/111 (66%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
IPFL+LA GVDNM I+ AVK E LE +I + EVGPSIT A++SE+LAF VG+F
Sbjct: 636 IPFLILAIGVDNMFIISTAVKGCHGENLLE-KIKGGMTEVGPSITAAAVSEILAFMVGTF 694
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
++PA F + AA+AV D++ Q+TAFVA++ D +R D F CI+
Sbjct: 695 TNIPALTTFCIQAAIAVFFDYIFQITAFVAILAWDEERKLKGICDVFVCIR 745
[105][TOP]
>UniRef100_Q9JLG3 Niemann-Pick type C1 protein n=1 Tax=Cricetulus griseus
RepID=Q9JLG3_CRIGR
Length = 1277
Score = 98.6 bits (244), Expect = 2e-19
Identities = 55/112 (49%), Positives = 73/112 (65%), Gaps = 2/112 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL--ELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV +R E L+ ++ L EV P++ L+S SE AF G
Sbjct: 690 IPFLVLAVGVDNIFILVQTYQRDERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFG 749
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCI 347
+ SMPA FS+FA LAVL+DF+LQ+T FV+L+ LD +R E R+D C+
Sbjct: 750 ALSSMPAVHTFSLFAGLAVLIDFLLQITCFVSLLGLDIKRQEKNRLDILCCV 801
[106][TOP]
>UniRef100_UPI000186EA3E Niemann-Pick C1 protein precursor, putative n=1 Tax=Pediculus
humanus corporis RepID=UPI000186EA3E
Length = 1278
Score = 98.2 bits (243), Expect = 3e-19
Identities = 57/111 (51%), Positives = 71/111 (63%), Gaps = 4/111 (3%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV R P E LE I L VGPS+TL SLSE F +G
Sbjct: 664 IPFLVLAVGVDNIFILVQTHNRLPREPNESLEEHIGRTLGVVGPSMTLTSLSESFCFFLG 723
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVD--CF 338
+MPA R F+++A +A+L+DF+ QVT FV+L+ LDS+R R D CF
Sbjct: 724 GLSNMPAVRAFALYAGMALLIDFIFQVTCFVSLLALDSRRQTAGRYDVCCF 774
[107][TOP]
>UniRef100_UPI000069EB67 Niemann-Pick C1 protein precursor. n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069EB67
Length = 1283
Score = 98.2 bits (243), Expect = 3e-19
Identities = 52/112 (46%), Positives = 75/112 (66%), Gaps = 2/112 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL--ELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ I+V +R + L+ +I L +V PSI L++ +E +AF +G
Sbjct: 696 IPFLVLAVGVDNIYIIVQRYQRDERLHDETLDQQIGRILGDVAPSIFLSAFAETVAFFLG 755
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCI 347
+ SMPA R FS+FA +AV LDF+LQ+T F++L+ LD +R E R+D C+
Sbjct: 756 ALSSMPAVRTFSLFAGMAVFLDFLLQITCFISLLSLDIRRQEKNRLDILCCV 807
[108][TOP]
>UniRef100_UPI000069EB66 Niemann-Pick C1 protein precursor. n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069EB66
Length = 1289
Score = 98.2 bits (243), Expect = 3e-19
Identities = 52/112 (46%), Positives = 75/112 (66%), Gaps = 2/112 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL--ELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ I+V +R + L+ +I L +V PSI L++ +E +AF +G
Sbjct: 702 IPFLVLAVGVDNIYIIVQRYQRDERLHDETLDQQIGRILGDVAPSIFLSAFAETVAFFLG 761
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCI 347
+ SMPA R FS+FA +AV LDF+LQ+T F++L+ LD +R E R+D C+
Sbjct: 762 ALSSMPAVRTFSLFAGMAVFLDFLLQITCFISLLSLDIRRQEKNRLDILCCV 813
[109][TOP]
>UniRef100_UPI000069EB65 Niemann-Pick C1 protein precursor. n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069EB65
Length = 1282
Score = 98.2 bits (243), Expect = 3e-19
Identities = 52/112 (46%), Positives = 75/112 (66%), Gaps = 2/112 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL--ELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ I+V +R + L+ +I L +V PSI L++ +E +AF +G
Sbjct: 695 IPFLVLAVGVDNIYIIVQRYQRDERLHDETLDQQIGRILGDVAPSIFLSAFAETVAFFLG 754
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCI 347
+ SMPA R FS+FA +AV LDF+LQ+T F++L+ LD +R E R+D C+
Sbjct: 755 ALSSMPAVRTFSLFAGMAVFLDFLLQITCFISLLSLDIRRQEKNRLDILCCV 806
[110][TOP]
>UniRef100_UPI000069EB64 Niemann-Pick C1 protein precursor. n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069EB64
Length = 1280
Score = 98.2 bits (243), Expect = 3e-19
Identities = 52/112 (46%), Positives = 75/112 (66%), Gaps = 2/112 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL--ELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ I+V +R + L+ +I L +V PSI L++ +E +AF +G
Sbjct: 693 IPFLVLAVGVDNIYIIVQRYQRDERLHDETLDQQIGRILGDVAPSIFLSAFAETVAFFLG 752
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCI 347
+ SMPA R FS+FA +AV LDF+LQ+T F++L+ LD +R E R+D C+
Sbjct: 753 ALSSMPAVRTFSLFAGMAVFLDFLLQITCFISLLSLDIRRQEKNRLDILCCV 804
[111][TOP]
>UniRef100_B4H144 GL15811 n=1 Tax=Drosophila persimilis RepID=B4H144_DROPE
Length = 1250
Score = 98.2 bits (243), Expect = 3e-19
Identities = 54/114 (47%), Positives = 74/114 (64%), Gaps = 3/114 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR---QPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ I+VH +R E E I A+ +VGPSI + SE FA+
Sbjct: 666 IPFLVLAVGVDNIFIMVHTFQRLDHSRFETTHEA-IGEAIGQVGPSILQTAGSEFACFAI 724
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
G+ MPA + F+M+AA A+L DF+LQ+TAFVAL+ +D +R D R+D C++
Sbjct: 725 GALSDMPAVKTFAMYAAAAILFDFLLQITAFVALMAIDQRRVLDGRLDMLCCVQ 778
[112][TOP]
>UniRef100_UPI0000EB3851 Niemann-Pick type C1 disease protein. n=1 Tax=Canis lupus familiaris
RepID=UPI0000EB3851
Length = 1285
Score = 97.8 bits (242), Expect = 3e-19
Identities = 54/112 (48%), Positives = 73/112 (65%), Gaps = 2/112 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV +R LE ++ L EV PS+ L+S SE +AF +G
Sbjct: 699 IPFLVLAVGVDNIFILVQTYQRDERLQGETLEQQLGRVLGEVAPSMFLSSFSEAVAFFLG 758
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCI 347
+ MPA FS+FA +AVL+DF+LQ+T FV+L+ LD +R E R+D C+
Sbjct: 759 ALSQMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDLKRQEKNRLDVLCCL 810
[113][TOP]
>UniRef100_UPI0000EB3850 Niemann-Pick type C1 disease protein. n=1 Tax=Canis lupus familiaris
RepID=UPI0000EB3850
Length = 1277
Score = 97.8 bits (242), Expect = 3e-19
Identities = 54/112 (48%), Positives = 73/112 (65%), Gaps = 2/112 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV +R LE ++ L EV PS+ L+S SE +AF +G
Sbjct: 691 IPFLVLAVGVDNIFILVQTYQRDERLQGETLEQQLGRVLGEVAPSMFLSSFSEAVAFFLG 750
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCI 347
+ MPA FS+FA +AVL+DF+LQ+T FV+L+ LD +R E R+D C+
Sbjct: 751 ALSQMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDLKRQEKNRLDVLCCL 802
[114][TOP]
>UniRef100_Q9N0Q0 Niemann-Pick type C1 disease protein n=1 Tax=Felis catus
RepID=Q9N0Q0_FELCA
Length = 1276
Score = 97.8 bits (242), Expect = 3e-19
Identities = 53/113 (46%), Positives = 74/113 (65%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL--ELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV +R L+ ++ L EV PS+ L+S SE +AF +G
Sbjct: 690 IPFLVLAVGVDNIFILVQTYQRDERLHGETLDQQLGRVLGEVAPSMFLSSFSEAVAFFLG 749
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ MPA FS+FA +AVL+DF+LQ+T FV+L+ LD +R E R+D C++
Sbjct: 750 ALSKMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNRLDVLCCVR 802
[115][TOP]
>UniRef100_Q9GK52 Niemann-Pick type C1 disease protein n=1 Tax=Canis lupus familiaris
RepID=Q9GK52_CANFA
Length = 1276
Score = 97.8 bits (242), Expect = 3e-19
Identities = 54/112 (48%), Positives = 73/112 (65%), Gaps = 2/112 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV +R LE ++ L EV PS+ L+S SE +AF +G
Sbjct: 690 IPFLVLAVGVDNIFILVQTYQRDERLQGETLEQQLGRVLGEVAPSMFLSSFSEAVAFFLG 749
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCI 347
+ MPA FS+FA +AVL+DF+LQ+T FV+L+ LD +R E R+D C+
Sbjct: 750 ALSQMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDLKRQEKNRLDVLCCL 801
[116][TOP]
>UniRef100_Q8MKD8 Niemann-Pick C1 n=1 Tax=Felis catus RepID=Q8MKD8_FELCA
Length = 1276
Score = 97.8 bits (242), Expect = 3e-19
Identities = 53/113 (46%), Positives = 74/113 (65%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL--ELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV +R L+ ++ L EV PS+ L+S SE +AF +G
Sbjct: 690 IPFLVLAVGVDNIFILVQTYQRDERLHGETLDQQLGRVLGEVAPSMFLSSFSEAVAFFLG 749
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ MPA FS+FA +AVL+DF+LQ+T FV+L+ LD +R E R+D C++
Sbjct: 750 ALSKMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNRLDVLCCVR 802
[117][TOP]
>UniRef100_Q8MI49 Mutant Niemann-Pick C1 n=1 Tax=Felis catus RepID=Q8MI49_FELCA
Length = 1276
Score = 97.8 bits (242), Expect = 3e-19
Identities = 53/113 (46%), Positives = 74/113 (65%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL--ELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV +R L+ ++ L EV PS+ L+S SE +AF +G
Sbjct: 690 IPFLVLAVGVDNIFILVQTYQRDERLHGETLDQQLGRVLGEVAPSMFLSSFSEAVAFFLG 749
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ MPA FS+FA +AVL+DF+LQ+T FV+L+ LD +R E R+D C++
Sbjct: 750 ALSKMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNRLDVLCCVR 802
[118][TOP]
>UniRef100_B4PYK8 GE17898 n=1 Tax=Drosophila yakuba RepID=B4PYK8_DROYA
Length = 1252
Score = 97.8 bits (242), Expect = 3e-19
Identities = 54/114 (47%), Positives = 75/114 (65%), Gaps = 3/114 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR---QPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ I+VH +R E E I A+ +VGPSI + SE+ FA+
Sbjct: 661 IPFLVLAVGVDNIFIMVHTYQRLDHSKFESTHEA-IGEAIGQVGPSILQTAGSEMACFAI 719
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
G MPA + F+M+AA+A+LLDF+LQ+TAFVAL+ +D +R R+D C++
Sbjct: 720 GCISDMPAVKTFAMYAAIAILLDFLLQITAFVALMAIDERRYMAGRLDMLCCVR 773
[119][TOP]
>UniRef100_UPI00017966B6 PREDICTED: similar to Niemann-Pick C1 n=1 Tax=Equus caballus
RepID=UPI00017966B6
Length = 1293
Score = 97.4 bits (241), Expect = 4e-19
Identities = 54/113 (47%), Positives = 74/113 (65%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV +R L+ ++ L EV PS+ L+S SE +AF +G
Sbjct: 706 IPFLVLAVGVDNIFILVQTYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLG 765
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ MPA FS+FA LAVL+DF+LQ+T FV+L+ LD +R E R+D C++
Sbjct: 766 ALSVMPAVHTFSLFAGLAVLIDFLLQITCFVSLLGLDIKRQEKNRLDVLCCLR 818
[120][TOP]
>UniRef100_UPI0000DB7411 PREDICTED: similar to Niemann-Pick Type C-1 CG5722-PA n=1 Tax=Apis
mellifera RepID=UPI0000DB7411
Length = 1238
Score = 97.4 bits (241), Expect = 4e-19
Identities = 48/113 (42%), Positives = 75/113 (66%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL--ELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ IL+H ++ P + + + L EVGPS+ L S+SE L F +G
Sbjct: 676 IPFLVLAVGVDNIFILIHTYEKNPKCDDETIHEHVGRILGEVGPSMLLTSISECLCFLIG 735
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ +MPA F+++A++++L++F+LQ+TAFV L+ L +R E + D C+K
Sbjct: 736 TLSTMPAVNTFALYASVSILINFLLQITAFVCLLSLHERRFEKRYFDVLCCLK 788
[121][TOP]
>UniRef100_UPI00016E1F22 UPI00016E1F22 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E1F22
Length = 1297
Score = 97.4 bits (241), Expect = 4e-19
Identities = 58/127 (45%), Positives = 82/127 (64%), Gaps = 4/127 (3%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGR---ISNALVEVGPSITLASLSEVLAFAV 188
+PFLVLA G DN+ I V +R + P E R I L V PS+ L SLSE + F +
Sbjct: 703 VPFLVLAVGADNIFIFVLEYQRD-VRRPGEKREEQIGRVLGTVAPSMLLCSLSESICFFL 761
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHA 368
G+ +MPA + F+++AALA+LLDFVLQ+TAFVAL+ LD +R + R + CIKV +
Sbjct: 762 GALSTMPAVKSFALYAALAILLDFVLQMTAFVALLSLDCRRQDSNRCELLSCIKVSTPRL 821
Query: 369 D-PDKGI 386
+ P++G+
Sbjct: 822 NKPNEGV 828
[122][TOP]
>UniRef100_UPI00016E1F21 UPI00016E1F21 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E1F21
Length = 1289
Score = 97.4 bits (241), Expect = 4e-19
Identities = 58/127 (45%), Positives = 82/127 (64%), Gaps = 4/127 (3%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGR---ISNALVEVGPSITLASLSEVLAFAV 188
+PFLVLA G DN+ I V +R + P E R I L V PS+ L SLSE + F +
Sbjct: 697 VPFLVLAVGADNIFIFVLEYQRD-VRRPGEKREEQIGRVLGTVAPSMLLCSLSESICFFL 755
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHA 368
G+ +MPA + F+++AALA+LLDFVLQ+TAFVAL+ LD +R + R + CIKV +
Sbjct: 756 GALSTMPAVKSFALYAALAILLDFVLQMTAFVALLSLDCRRQDSNRCELLSCIKVSTPRL 815
Query: 369 D-PDKGI 386
+ P++G+
Sbjct: 816 NKPNEGV 822
[123][TOP]
>UniRef100_Q7YU59 RE56428p n=1 Tax=Drosophila melanogaster RepID=Q7YU59_DROME
Length = 1287
Score = 97.4 bits (241), Expect = 4e-19
Identities = 55/112 (49%), Positives = 76/112 (67%), Gaps = 5/112 (4%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR---QPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ILV +R +P E LE ++ L +VGPSI L SLSE F +
Sbjct: 692 IPFLVLAVGVDNIFILVQTHQRDQRKPNET-LEQQVGRILGKVGPSILLTSLSESFCFFL 750
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVD--CF 338
G MPA R F+++A +A+++DF+LQ+T FV+L LD++R E+ R+D CF
Sbjct: 751 GGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCF 802
[124][TOP]
>UniRef100_UPI00001830DD Cdig2 protein n=1 Tax=Rattus norvegicus RepID=UPI00001830DD
Length = 1278
Score = 97.1 bits (240), Expect = 6e-19
Identities = 53/113 (46%), Positives = 73/113 (64%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL--ELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV +R E L+ ++ L EV P++ L+S SE AF G
Sbjct: 691 IPFLVLAVGVDNIFILVQTYQRDERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFG 750
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ SMPA FS+FA +AVL+DF+LQ+T FV+ + LD +R E R+D C++
Sbjct: 751 ALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSFLGLDIKRQEKNRLDILCCVR 803
[125][TOP]
>UniRef100_Q17RV5 NPC1-like 1 protein n=2 Tax=Homo sapiens RepID=Q17RV5_HUMAN
Length = 1332
Score = 97.1 bits (240), Expect = 6e-19
Identities = 54/113 (47%), Positives = 73/113 (64%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFLVL+ G DN+ I V +R P P E I AL V PS+ L SLSE + F +G
Sbjct: 702 VPFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLG 761
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ MPA R F++ + LAV+LDF+LQ++AFVAL+ LDS+R E R+D C+K
Sbjct: 762 ALTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEASRLDVCCCVK 814
[126][TOP]
>UniRef100_B7ZLE6 NPC1L1 protein n=1 Tax=Homo sapiens RepID=B7ZLE6_HUMAN
Length = 1286
Score = 97.1 bits (240), Expect = 6e-19
Identities = 54/113 (47%), Positives = 73/113 (64%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFLVL+ G DN+ I V +R P P E I AL V PS+ L SLSE + F +G
Sbjct: 702 VPFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLG 761
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ MPA R F++ + LAV+LDF+LQ++AFVAL+ LDS+R E R+D C+K
Sbjct: 762 ALTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEASRLDVCCCVK 814
[127][TOP]
>UniRef100_A8MSP5 NPC1 (Niemann-Pick disease, type C1, gene)-like 1, isoform CRA_a n=1
Tax=Homo sapiens RepID=A8MSP5_HUMAN
Length = 1359
Score = 97.1 bits (240), Expect = 6e-19
Identities = 54/113 (47%), Positives = 73/113 (64%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFLVL+ G DN+ I V +R P P E I AL V PS+ L SLSE + F +G
Sbjct: 702 VPFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLG 761
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ MPA R F++ + LAV+LDF+LQ++AFVAL+ LDS+R E R+D C+K
Sbjct: 762 ALTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEASRLDVCCCVK 814
[128][TOP]
>UniRef100_Q9UHC9 Niemann-Pick C1-like protein 1 n=1 Tax=Homo sapiens RepID=NPCL1_HUMAN
Length = 1359
Score = 97.1 bits (240), Expect = 6e-19
Identities = 54/113 (47%), Positives = 73/113 (64%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFLVL+ G DN+ I V +R P P E I AL V PS+ L SLSE + F +G
Sbjct: 702 VPFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLG 761
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ MPA R F++ + LAV+LDF+LQ++AFVAL+ LDS+R E R+D C+K
Sbjct: 762 ALTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEASRLDVCCCVK 814
[129][TOP]
>UniRef100_UPI00005638CC Niemann Pick type C1 n=1 Tax=Mus musculus RepID=UPI00005638CC
Length = 1277
Score = 96.7 bits (239), Expect = 7e-19
Identities = 53/113 (46%), Positives = 73/113 (64%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL--ELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV +R E L+ ++ L EV P++ L+S SE AF G
Sbjct: 690 IPFLVLAVGVDNIFILVQTYQRDERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFG 749
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ SMPA FS+FA +AVL+DF+LQ+T FV+L+ LD +R E +D C++
Sbjct: 750 ALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNHLDILCCVR 802
[130][TOP]
>UniRef100_Q4RWY5 Chromosome 15 SCAF14981, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4RWY5_TETNG
Length = 1209
Score = 96.7 bits (239), Expect = 7e-19
Identities = 56/128 (43%), Positives = 80/128 (62%), Gaps = 16/128 (12%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAF-- 182
IPFLVLA GVDN+ I+V ++R +P L +I L +V PS+ L+S SE +AF
Sbjct: 642 IPFLVLAVGVDNIFIIVQTLQRDE-RMPHEELHQQIGRILGDVAPSMFLSSFSETVAFFL 700
Query: 183 -----------AVGSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRV 329
A+G+ +MPA R FS+FA LAV +DF+LQ++ FV+L+ LD+ R ED R+
Sbjct: 701 GKFNSSLKLFEAIGALSNMPAARTFSLFAGLAVFIDFLLQISCFVSLLGLDASRQEDNRL 760
Query: 330 DCFPCIKV 353
D C+K+
Sbjct: 761 DIVCCVKL 768
[131][TOP]
>UniRef100_Q7TMD4 Niemann Pick type C1 n=1 Tax=Mus musculus RepID=Q7TMD4_MOUSE
Length = 1277
Score = 96.7 bits (239), Expect = 7e-19
Identities = 53/113 (46%), Positives = 73/113 (64%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL--ELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV +R E L+ ++ L EV P++ L+S SE AF G
Sbjct: 690 IPFLVLAVGVDNIFILVQTYQRDERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFG 749
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ SMPA FS+FA +AVL+DF+LQ+T FV+L+ LD +R E +D C++
Sbjct: 750 ALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNHLDILCCVR 802
[132][TOP]
>UniRef100_Q3U2B2 Putative uncharacterized protein n=1 Tax=Mus musculus
RepID=Q3U2B2_MOUSE
Length = 1094
Score = 96.7 bits (239), Expect = 7e-19
Identities = 53/113 (46%), Positives = 73/113 (64%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL--ELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV +R E L+ ++ L EV P++ L+S SE AF G
Sbjct: 690 IPFLVLAVGVDNIFILVQTYQRDERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFG 749
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ SMPA FS+FA +AVL+DF+LQ+T FV+L+ LD +R E +D C++
Sbjct: 750 ALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNHLDILCCVR 802
[133][TOP]
>UniRef100_A0MJA7 Niemann-Pick C1-like 1 protein n=1 Tax=Oryctolagus cuniculus
RepID=A0MJA7_RABIT
Length = 1325
Score = 96.7 bits (239), Expect = 7e-19
Identities = 56/113 (49%), Positives = 72/113 (63%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL--ELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFLVLA G DN+ ILV +R P E E I AL V PS+ L SLSE + F +G
Sbjct: 701 VPFLVLAVGADNIFILVLEYQRLPRRPEESREAHIGRALGRVAPSMLLCSLSETICFFLG 760
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ MPA R F++ + LAV LDF+LQ+TAFVAL+ LDS+R E R D C++
Sbjct: 761 ALTPMPAVRTFALTSGLAVQLDFLLQMTAFVALLSLDSKRQEASRPDVCCCLE 813
[134][TOP]
>UniRef100_A0MJA5 Niemann-Pick C1-like 1 protein n=2 Tax=Macaca RepID=A0MJA5_MACMU
Length = 1332
Score = 96.7 bits (239), Expect = 7e-19
Identities = 54/113 (47%), Positives = 73/113 (64%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFLVL+ G DN+ I V +R P P E I AL V PS+ L SLSE + F +G
Sbjct: 702 VPFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLG 761
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ MPA R F++ + LAV+LDF+LQ++AFVAL+ LDS+R E R+D C+K
Sbjct: 762 ALTPMPAVRTFALTSGLAVVLDFLLQMSAFVALLSLDSKRQEASRLDVCCCVK 814
[135][TOP]
>UniRef100_B4NZ62 GE26328 n=1 Tax=Drosophila yakuba RepID=B4NZ62_DROYA
Length = 1287
Score = 96.7 bits (239), Expect = 7e-19
Identities = 55/112 (49%), Positives = 76/112 (67%), Gaps = 5/112 (4%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR---QPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ILV +R +P E LE +I L +VGPS+ L SLSE F +
Sbjct: 692 IPFLVLAVGVDNIFILVQTHQRDQRKPNET-LEQQIGRILGKVGPSMLLTSLSESFCFFL 750
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVD--CF 338
G MPA R F+++A +A+++DF+LQ+T FV+L LD++R E+ R+D CF
Sbjct: 751 GGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCF 802
[136][TOP]
>UniRef100_B3N0K3 GF21705 n=1 Tax=Drosophila ananassae RepID=B3N0K3_DROAN
Length = 1323
Score = 96.7 bits (239), Expect = 7e-19
Identities = 51/113 (45%), Positives = 75/113 (66%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR-QPLELP-LEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ I+VH R + P I A+ ++GPSI + SE+ FA+G
Sbjct: 652 IPFLVLAVGVDNIFIMVHTYHRLDHSQFPSTHEAIGEAIGQIGPSILQTAGSEMACFAIG 711
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
MPA + F+M+AA+A+LL+F+LQ+TAFVAL+ +D +R + R+D C++
Sbjct: 712 CIADMPAVKTFAMYAAIAILLNFLLQITAFVALMAIDERRYQAGRLDMLCCVR 764
[137][TOP]
>UniRef100_C5MCB4 Putative uncharacterized protein n=1 Tax=Candida tropicalis MYA-3404
RepID=C5MCB4_CANTT
Length = 1259
Score = 96.7 bits (239), Expect = 7e-19
Identities = 52/123 (42%), Positives = 80/123 (65%), Gaps = 5/123 (4%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAV----KRQP-LELPLEGRISNALVEVGPSITLASLSEVLAF 182
IPFLVLA G+DN+ ++VH + + QP E+P+ RI+ AL +GPS ++++ +V F
Sbjct: 651 IPFLVLAIGIDNIFLIVHELHVISEVQPDKEIPI--RIAQALKNIGPSCFISAILQVSMF 708
Query: 183 AVGSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSF 362
+ + + MPA R F+ + AVL++F+LQ+T F+ L+ LD +R E+ RVDC PCI V
Sbjct: 709 LLATSVGMPAVRNFAFYGGGAVLINFLLQMTCFIGLLSLDQKRLEENRVDCVPCIAVAPI 768
Query: 363 HAD 371
D
Sbjct: 769 SLD 771
[138][TOP]
>UniRef100_O35604 Niemann-Pick C1 protein n=1 Tax=Mus musculus RepID=NPC1_MOUSE
Length = 1278
Score = 96.7 bits (239), Expect = 7e-19
Identities = 53/113 (46%), Positives = 73/113 (64%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL--ELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV +R E L+ ++ L EV P++ L+S SE AF G
Sbjct: 691 IPFLVLAVGVDNIFILVQTYQRDERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFG 750
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ SMPA FS+FA +AVL+DF+LQ+T FV+L+ LD +R E +D C++
Sbjct: 751 ALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNHLDILCCVR 803
[139][TOP]
>UniRef100_Q9VL24 Niemann-Pick type C-1 n=1 Tax=Drosophila melanogaster
RepID=Q9VL24_DROME
Length = 1287
Score = 96.3 bits (238), Expect = 1e-18
Identities = 54/112 (48%), Positives = 76/112 (67%), Gaps = 5/112 (4%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR---QPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ILV +R +P E LE ++ L +VGPS+ L SLSE F +
Sbjct: 692 IPFLVLAVGVDNIFILVQTHQRDQRKPNET-LEQQVGRILGKVGPSMLLTSLSESFCFFL 750
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVD--CF 338
G MPA R F+++A +A+++DF+LQ+T FV+L LD++R E+ R+D CF
Sbjct: 751 GGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCF 802
[140][TOP]
>UniRef100_Q9U5W1 NPC1 protein n=1 Tax=Drosophila melanogaster RepID=Q9U5W1_DROME
Length = 1287
Score = 96.3 bits (238), Expect = 1e-18
Identities = 54/112 (48%), Positives = 76/112 (67%), Gaps = 5/112 (4%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR---QPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ILV +R +P E LE ++ L +VGPS+ L SLSE F +
Sbjct: 692 IPFLVLAVGVDNIFILVQTHQRDQRKPNET-LEQQVGRILGKVGPSMLLTSLSESFCFFL 750
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVD--CF 338
G MPA R F+++A +A+++DF+LQ+T FV+L LD++R E+ R+D CF
Sbjct: 751 GGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCF 802
[141][TOP]
>UniRef100_B4Q8Q7 GD22294 n=1 Tax=Drosophila simulans RepID=B4Q8Q7_DROSI
Length = 1251
Score = 96.3 bits (238), Expect = 1e-18
Identities = 54/112 (48%), Positives = 76/112 (67%), Gaps = 5/112 (4%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR---QPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ILV +R +P E LE ++ L +VGPS+ L SLSE F +
Sbjct: 692 IPFLVLAVGVDNIFILVQTHQRDQRKPNET-LEQQVGRILGKVGPSMLLTSLSESFCFFL 750
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVD--CF 338
G MPA R F+++A +A+++DF+LQ+T FV+L LD++R E+ R+D CF
Sbjct: 751 GGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCF 802
[142][TOP]
>UniRef100_B4HWH4 GM11941 n=1 Tax=Drosophila sechellia RepID=B4HWH4_DROSE
Length = 1287
Score = 96.3 bits (238), Expect = 1e-18
Identities = 54/112 (48%), Positives = 76/112 (67%), Gaps = 5/112 (4%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR---QPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ILV +R +P E LE ++ L +VGPS+ L SLSE F +
Sbjct: 692 IPFLVLAVGVDNIFILVQTHQRDQRKPNET-LEQQVGRILGKVGPSMLLTSLSESFCFFL 750
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVD--CF 338
G MPA R F+++A +A+++DF+LQ+T FV+L LD++R E+ R+D CF
Sbjct: 751 GGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCF 802
[143][TOP]
>UniRef100_B3MPM8 GF14130 n=1 Tax=Drosophila ananassae RepID=B3MPM8_DROAN
Length = 1286
Score = 96.3 bits (238), Expect = 1e-18
Identities = 55/112 (49%), Positives = 75/112 (66%), Gaps = 5/112 (4%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR---QPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ILV +R +P E LE +I L VGPS+ L SLSE F +
Sbjct: 691 IPFLVLAVGVDNIFILVQTHQRDQRKPNET-LEQQIGRILGRVGPSMLLTSLSESFCFFL 749
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVD--CF 338
G MPA R F+++A +A+++DF+LQ+T FV+L LD++R E+ R+D CF
Sbjct: 750 GGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRKEENRMDICCF 801
[144][TOP]
>UniRef100_A0MJA4 Niemann-Pick C1-like 1 protein n=1 Tax=Canis lupus familiaris
RepID=A0MJA4_CANFA
Length = 1325
Score = 95.9 bits (237), Expect = 1e-18
Identities = 52/112 (46%), Positives = 71/112 (63%), Gaps = 2/112 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFLVLA G DN+ I V +R P P E I AL V PS+ L SLSE + F +G
Sbjct: 702 VPFLVLAVGADNIFIFVLEYQRLPRRPGEPREAHIGRALGSVAPSMLLCSLSEAICFFLG 761
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCI 347
+ MPA + F++ + A++LDF+LQV+AFVAL+ LDS+R E R+D C+
Sbjct: 762 ALTPMPAVKTFALISGFAIVLDFLLQVSAFVALLSLDSRRQEASRLDVCCCV 813
[145][TOP]
>UniRef100_B3N938 GG23970 n=1 Tax=Drosophila erecta RepID=B3N938_DROER
Length = 1268
Score = 95.9 bits (237), Expect = 1e-18
Identities = 54/112 (48%), Positives = 76/112 (67%), Gaps = 5/112 (4%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR---QPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ILV +R +P E +E +I L +VGPS+ L SLSE F +
Sbjct: 674 IPFLVLAVGVDNIFILVQTHQRDQRKPNET-IEQQIGRILGKVGPSMLLTSLSESFCFFL 732
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVD--CF 338
G MPA R F+++A +A+++DF+LQ+T FV+L LD++R E+ R+D CF
Sbjct: 733 GGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCF 784
[146][TOP]
>UniRef100_B4MSW0 GK19822 n=1 Tax=Drosophila willistoni RepID=B4MSW0_DROWI
Length = 1264
Score = 95.5 bits (236), Expect = 2e-18
Identities = 51/113 (45%), Positives = 72/113 (63%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLE--LPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ I+VH +R + I A+ +VGPSI + SE FA+G
Sbjct: 670 IPFLVLAVGVDNIFIMVHTYQRLDHKRFATTHEAIGEAIGQVGPSILQTAGSEFACFAIG 729
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+ MPA + F+ +AA A+LLDF+ Q+TAFVAL+ +D +R D R+D C++
Sbjct: 730 AISDMPAVKTFAQYAAAAILLDFLFQITAFVALMAIDERRFLDGRLDMLCCVR 782
[147][TOP]
>UniRef100_UPI000069E05C Niemann-Pick C1-like protein 1 precursor. n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI000069E05C
Length = 1228
Score = 95.1 bits (235), Expect = 2e-18
Identities = 57/114 (50%), Positives = 74/114 (64%), Gaps = 3/114 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR---QPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
+PFLVLA G DN+ I V ++R +P E E +I L V PS+ L S+SE L F +
Sbjct: 639 VPFLVLAVGADNIFIFVLELQRDDRRPGERR-EEQIGRVLGNVAPSMLLCSVSESLCFFL 697
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
G+ MPA R F++ AALA+LLDFVLQ++ FVAL+ LDS+R E R D CIK
Sbjct: 698 GALTKMPAVRTFALNAALAILLDFVLQISMFVALVSLDSKRQEASRYDICCCIK 751
[148][TOP]
>UniRef100_UPI000069E05B Niemann-Pick C1-like protein 1 precursor. n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069E05B
Length = 1260
Score = 95.1 bits (235), Expect = 2e-18
Identities = 57/114 (50%), Positives = 74/114 (64%), Gaps = 3/114 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR---QPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
+PFLVLA G DN+ I V ++R +P E E +I L V PS+ L S+SE L F +
Sbjct: 697 VPFLVLAVGADNIFIFVLELQRDDRRPGERR-EEQIGRVLGNVAPSMLLCSVSESLCFFL 755
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
G+ MPA R F++ AALA+LLDFVLQ++ FVAL+ LDS+R E R D CIK
Sbjct: 756 GALTKMPAVRTFALNAALAILLDFVLQISMFVALVSLDSKRQEASRYDICCCIK 809
[149][TOP]
>UniRef100_UPI000069E05A Niemann-Pick C1-like protein 1 precursor. n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069E05A
Length = 1319
Score = 95.1 bits (235), Expect = 2e-18
Identities = 57/114 (50%), Positives = 74/114 (64%), Gaps = 3/114 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR---QPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
+PFLVLA G DN+ I V ++R +P E E +I L V PS+ L S+SE L F +
Sbjct: 711 VPFLVLAVGADNIFIFVLELQRDDRRPGERR-EEQIGRVLGNVAPSMLLCSVSESLCFFL 769
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
G+ MPA R F++ AALA+LLDFVLQ++ FVAL+ LDS+R E R D CIK
Sbjct: 770 GALTKMPAVRTFALNAALAILLDFVLQISMFVALVSLDSKRQEASRYDICCCIK 823
[150][TOP]
>UniRef100_UPI00017610E4 PREDICTED: similar to NPC1 (Niemann-Pick disease, type C1,
gene)-like 1 n=1 Tax=Danio rerio RepID=UPI00017610E4
Length = 1087
Score = 94.7 bits (234), Expect = 3e-18
Identities = 58/127 (45%), Positives = 81/127 (63%), Gaps = 4/127 (3%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGR---ISNALVEVGPSITLASLSEVLAFAV 188
+PFLVLA G DN+ I V +R L P E R I L V PS+ L SLSE + F +
Sbjct: 572 VPFLVLAVGADNIFIFVLEYQRD-LRRPGEQREEQIGRVLGNVAPSMLLCSLSESVCFFL 630
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHA 368
G+ +MPA + F+++AALAVL+DFVLQ+TAFVAL+ LD++R + R + C+ V +
Sbjct: 631 GALSTMPAVKSFALYAALAVLMDFVLQMTAFVALLSLDARRQDSNRCEIACCVTVDTPRP 690
Query: 369 D-PDKGI 386
P++GI
Sbjct: 691 QKPNEGI 697
[151][TOP]
>UniRef100_UPI000023DFE9 hypothetical protein FG09254.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023DFE9
Length = 1295
Score = 94.7 bits (234), Expect = 3e-18
Identities = 49/111 (44%), Positives = 76/111 (68%), Gaps = 3/111 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPF+VLA GVDN+ ++VH ++R P +E R++ AL +GPSI ++L+E +AFA+
Sbjct: 686 IPFIVLAVGVDNIFLIVHELERVNTSFPDQMVEERVARALGRMGPSILFSALTETVAFAL 745
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFP 341
G+ + MPA R F+ +AA AV ++ VLQ+T FV+ + L+ R ED R + +P
Sbjct: 746 GTAVGMPAVRNFAAYAAGAVFVNAVLQMTMFVSFLSLNQMRVEDHRCELWP 796
[152][TOP]
>UniRef100_UPI0001A2D2B7 Novel protein similar to human and mouse intersectin 2 (ITSN2) n=1
Tax=Danio rerio RepID=UPI0001A2D2B7
Length = 1260
Score = 94.7 bits (234), Expect = 3e-18
Identities = 58/127 (45%), Positives = 81/127 (63%), Gaps = 4/127 (3%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGR---ISNALVEVGPSITLASLSEVLAFAV 188
+PFLVLA G DN+ I V +R L P E R I L V PS+ L SLSE + F +
Sbjct: 678 VPFLVLAVGADNIFIFVLEYQRD-LRRPGEQREEQIGRVLGNVAPSMLLCSLSESVCFFL 736
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHA 368
G+ +MPA + F+++AALAVL+DFVLQ+TAFVAL+ LD++R + R + C+ V +
Sbjct: 737 GALSTMPAVKSFALYAALAVLMDFVLQMTAFVALLSLDARRQDSNRCEIACCVTVDTPRP 796
Query: 369 D-PDKGI 386
P++GI
Sbjct: 797 QKPNEGI 803
[153][TOP]
>UniRef100_Q7Q409 AGAP008137-PA n=1 Tax=Anopheles gambiae RepID=Q7Q409_ANOGA
Length = 1192
Score = 94.7 bits (234), Expect = 3e-18
Identities = 55/112 (49%), Positives = 72/112 (64%), Gaps = 5/112 (4%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR---QPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ILV +R +P E E I L VGPSI L S+SE F +
Sbjct: 593 IPFLVLAVGVDNIFILVQTHQRDTKKPTETHAE-HIGRILGRVGPSILLTSVSESCCFFL 651
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVD--CF 338
G MPA R F+++A +A+L+DF+LQ+T FV+L+ LD+ R D R+D CF
Sbjct: 652 GGLSDMPAVRAFALYAGMALLIDFILQITCFVSLLALDTIRQTDNRLDVLCF 703
[154][TOP]
>UniRef100_UPI0000F2B5DF PREDICTED: similar to Niemann-Pick C1-like 1 protein n=1
Tax=Monodelphis domestica RepID=UPI0000F2B5DF
Length = 1331
Score = 94.4 bits (233), Expect = 4e-18
Identities = 53/112 (47%), Positives = 71/112 (63%), Gaps = 2/112 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL--ELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFLVLA G DN+ I V +R P E E I L V PS+ L SLSE + F +G
Sbjct: 699 VPFLVLAVGADNIFIFVLEYQRLPRHSEESREVHIGRVLGTVAPSMLLCSLSEAICFFLG 758
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCI 347
+ SMPA R F++ A LA++ DF+LQ++AFVAL+ LDS+R E R+D C+
Sbjct: 759 ALTSMPAVRTFALTAGLAIIFDFLLQMSAFVALLSLDSKRQEASRLDICCCV 810
[155][TOP]
>UniRef100_Q6T3U3 Niemann-Pick C1-like protein 1 n=1 Tax=Rattus norvegicus
RepID=NPCL1_RAT
Length = 1331
Score = 94.4 bits (233), Expect = 4e-18
Identities = 55/124 (44%), Positives = 73/124 (58%), Gaps = 3/124 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGR---ISNALVEVGPSITLASLSEVLAFAV 188
+PFLVLA G DN+ I V +R P +P E R I L V PS+ L SLSE + F +
Sbjct: 702 VPFLVLAVGADNIFIFVLEYQRLP-RMPGEQREAHIGRTLGSVAPSMLLCSLSEAICFFL 760
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHA 368
G+ MPA R F++ + LA++LDF+LQ+TAFVAL+ LDS+R E R D C
Sbjct: 761 GALTPMPAVRTFALTSGLAIILDFLLQMTAFVALLSLDSKRQEASRPDVLCCFSTRKLPP 820
Query: 369 DPDK 380
+K
Sbjct: 821 PKEK 824
[156][TOP]
>UniRef100_P56941 Niemann-Pick C1 protein n=1 Tax=Sus scrofa RepID=NPC1_PIG
Length = 1277
Score = 94.4 bits (233), Expect = 4e-18
Identities = 52/113 (46%), Positives = 73/113 (64%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV +R L+ ++ L EV PS+ L+S SE +AF +G
Sbjct: 690 IPFLVLAVGVDNIFILVQTYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLG 749
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+PA FS+FA +AVL+DF+LQ+T FV+L+ LD +R E R+D C++
Sbjct: 750 GLSVVPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNRLDVVCCVQ 802
[157][TOP]
>UniRef100_B5DSD6 GA25612 n=1 Tax=Drosophila pseudoobscura pseudoobscura
RepID=B5DSD6_DROPS
Length = 487
Score = 94.0 bits (232), Expect = 5e-18
Identities = 52/111 (46%), Positives = 73/111 (65%), Gaps = 4/111 (3%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPL--EGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV +R +L E +I L VGPS+ L SLSE F +G
Sbjct: 196 IPFLVLAVGVDNIFILVQTHQRDHRKLNELHEQQIGRILGRVGPSMLLTSLSESFCFFLG 255
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVD--CF 338
MPA + F+++A +A+++DF+LQ+T FV+L LD++R E+ R+D CF
Sbjct: 256 GLSDMPAVKAFALYAGIALIIDFLLQITCFVSLFTLDTKRKEENRLDICCF 306
[158][TOP]
>UniRef100_A5E1Z8 Putative uncharacterized protein n=1 Tax=Lodderomyces elongisporus
RepID=A5E1Z8_LODEL
Length = 1191
Score = 94.0 bits (232), Expect = 5e-18
Identities = 52/136 (38%), Positives = 86/136 (63%), Gaps = 10/136 (7%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR-----QPLELPLEGRISNALVEVGPSITLASLSEVLAF 182
IPFLVLA GVDN+ ++VH + + L++P+ RI+ A+ +GPS ++++ ++ F
Sbjct: 501 IPFLVLAIGVDNIFLIVHELHKISEHEPDLDIPI--RIAFAMRNIGPSCFISAILQISMF 558
Query: 183 AVGSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDC-----FPCI 347
+ + + MPA + F++++A AV ++F+LQ+T FV+L+ LD QR E RVDC P I
Sbjct: 559 LLATAVDMPAVKNFAIYSAGAVAINFILQMTCFVSLLALDQQRMESNRVDCAPWITIPAI 618
Query: 348 KVHSFHADPDKGIRQR 395
++H D +G R R
Sbjct: 619 RIHG-GQDEARGTRNR 633
[159][TOP]
>UniRef100_UPI0001795FBF PREDICTED: similar to NPC1 (Niemann-Pick disease, type C1, gene)-like
1 n=1 Tax=Equus caballus RepID=UPI0001795FBF
Length = 1329
Score = 93.6 bits (231), Expect = 6e-18
Identities = 53/111 (47%), Positives = 70/111 (63%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFLVLA G DN+ I V +R P E I AL VGPS+ L SLSE + F +G
Sbjct: 701 VPFLVLAVGADNIFIFVLEYQRLPRRAGEKREAHIGRALGRVGPSMLLCSLSEAICFFLG 760
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ SMPA R F++ + AV+LDF+LQ++AFVAL+ LD +R E R+D C
Sbjct: 761 ALTSMPAVRTFALTSGFAVILDFLLQMSAFVALLSLDCRRQEALRLDFCCC 811
[160][TOP]
>UniRef100_B0JYK2 NPC1 protein n=2 Tax=Bos taurus RepID=B0JYK2_BOVIN
Length = 1277
Score = 93.6 bits (231), Expect = 6e-18
Identities = 51/112 (45%), Positives = 72/112 (64%), Gaps = 2/112 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV +R L+ ++ L EV PS+ L+S +E +AF +G
Sbjct: 690 IPFLVLAVGVDNIFILVQTYQRDERLQGETLDQQVGRVLGEVAPSMFLSSFAETVAFFLG 749
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCI 347
MPA FS+FA +AVL+DF+LQ+T FV+L+ LD +R E ++D C+
Sbjct: 750 GLSVMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNQLDVLCCV 801
[161][TOP]
>UniRef100_A3KMG9 Npc1l1 protein (Fragment) n=1 Tax=Mus musculus RepID=A3KMG9_MOUSE
Length = 1332
Score = 93.6 bits (231), Expect = 6e-18
Identities = 54/112 (48%), Positives = 71/112 (63%), Gaps = 3/112 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGR---ISNALVEVGPSITLASLSEVLAFAV 188
+PFLVLA G DN+ I V +R P +P E R I L V PS+ L SLSE + F +
Sbjct: 701 VPFLVLAVGADNIFIFVLEYQRLP-RMPGEQREAHIGRTLGSVAPSMLLCSLSEAICFFL 759
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
G+ SMPA R F++ + LA++ DF+LQ+TAFVAL+ LDS+R E R D C
Sbjct: 760 GALTSMPAVRTFALTSGLAIIFDFLLQMTAFVALLSLDSKRQEASRPDVVCC 811
[162][TOP]
>UniRef100_Q6T3U4 Niemann-Pick C1-like protein 1 n=1 Tax=Mus musculus RepID=NPCL1_MOUSE
Length = 1333
Score = 93.6 bits (231), Expect = 6e-18
Identities = 54/112 (48%), Positives = 71/112 (63%), Gaps = 3/112 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGR---ISNALVEVGPSITLASLSEVLAFAV 188
+PFLVLA G DN+ I V +R P +P E R I L V PS+ L SLSE + F +
Sbjct: 702 VPFLVLAVGADNIFIFVLEYQRLP-RMPGEQREAHIGRTLGSVAPSMLLCSLSEAICFFL 760
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
G+ SMPA R F++ + LA++ DF+LQ+TAFVAL+ LDS+R E R D C
Sbjct: 761 GALTSMPAVRTFALTSGLAIIFDFLLQMTAFVALLSLDSKRQEASRPDVVCC 812
[163][TOP]
>UniRef100_A0MJA8 Niemann-Pick C1-like 1 protein n=1 Tax=Mesocricetus auratus
RepID=A0MJA8_MESAU
Length = 1328
Score = 92.8 bits (229), Expect = 1e-17
Identities = 52/112 (46%), Positives = 69/112 (61%), Gaps = 2/112 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFLVLA G DN+ I V +R P E I L V PS+ L SLSE + F +G
Sbjct: 703 VPFLVLAVGADNIFIFVLEYQRLPRRPGEQREAHIGRTLGSVAPSMLLCSLSEAVCFFLG 762
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCI 347
+ MPA R F++ A L+++LDF+LQ+TAFVAL+ LDS+R E R D C+
Sbjct: 763 ALTPMPAVRTFALTAGLSIILDFLLQMTAFVALLSLDSKRQEASRPDILCCL 814
[164][TOP]
>UniRef100_UPI0001924FA4 PREDICTED: similar to predicted protein n=1 Tax=Hydra
magnipapillata RepID=UPI0001924FA4
Length = 920
Score = 92.4 bits (228), Expect = 1e-17
Identities = 54/112 (48%), Positives = 73/112 (65%), Gaps = 3/112 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVK---RQPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ILV A++ R P E E ++ L VGPS+ L+SLSE +AF
Sbjct: 299 IPFLVLAVGVDNIFILVQALQWDDRLPNETVGE-QVGRVLGMVGPSMLLSSLSESVAFGF 357
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
G MPA FS+FAALAV+ +F+LQ+T VA++ LD++R + + D C
Sbjct: 358 GGLSKMPAVHTFSIFAALAVVFNFLLQITMLVAVVALDAKRQANNKYDVICC 409
[165][TOP]
>UniRef100_UPI00005BC4A6 PREDICTED: similar to NPC1 (Niemann-Pick disease, type C1, gene)-like
1 n=1 Tax=Bos taurus RepID=UPI00005BC4A6
Length = 1333
Score = 92.4 bits (228), Expect = 1e-17
Identities = 53/111 (47%), Positives = 69/111 (62%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFLVLA G DN+ I V +R P E I AL V PS+ L SLSE + F +G
Sbjct: 704 VPFLVLAVGADNIFIFVLEYQRLPRRPGEEREAHIGRALGRVAPSMLLCSLSEAICFFLG 763
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ MPA R F++ + AVLLDF+LQ++AFVAL+ LDS+R E R+D C
Sbjct: 764 ALTPMPAVRTFALTSGFAVLLDFLLQMSAFVALLSLDSRRQEASRMDICCC 814
[166][TOP]
>UniRef100_UPI00017B4C1E UPI00017B4C1E related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B4C1E
Length = 1213
Score = 92.4 bits (228), Expect = 1e-17
Identities = 54/115 (46%), Positives = 73/115 (63%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGR---ISNALVEVGPSITLASLSEVLAFAV 188
+PFLVLA G DN+ I V +R + P E R I L V PS+ L SLSE + F
Sbjct: 627 VPFLVLAVGADNIFIFVLEYQRD-VRRPGEKREEQIGRILGNVAPSMLLCSLSESICFFF 685
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
G+ +MPA + F+++AA+A+LLDF LQ+TAFVAL+ LD +R + R + CIKV
Sbjct: 686 GALSTMPAVKSFALYAAVAILLDFALQMTAFVALLSLDCRRQDSNRCELLCCIKV 740
[167][TOP]
>UniRef100_UPI00019513D7 UPI00019513D7 related cluster n=1 Tax=Bos taurus RepID=UPI00019513D7
Length = 1324
Score = 92.4 bits (228), Expect = 1e-17
Identities = 53/111 (47%), Positives = 69/111 (62%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFLVLA G DN+ I V +R P E I AL V PS+ L SLSE + F +G
Sbjct: 704 VPFLVLAVGADNIFIFVLEYQRLPRRPGEEREAHIGRALGRVAPSMLLCSLSEAICFFLG 763
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ MPA R F++ + AVLLDF+LQ++AFVAL+ LDS+R E R+D C
Sbjct: 764 ALTPMPAVRTFALTSGFAVLLDFLLQMSAFVALLSLDSRRQEASRMDICCC 814
[168][TOP]
>UniRef100_Q4T749 Chromosome undetermined SCAF8317, whole genome shotgun sequence.
(Fragment) n=1 Tax=Tetraodon nigroviridis
RepID=Q4T749_TETNG
Length = 1132
Score = 92.4 bits (228), Expect = 1e-17
Identities = 54/115 (46%), Positives = 73/115 (63%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGR---ISNALVEVGPSITLASLSEVLAFAV 188
+PFLVLA G DN+ I V +R + P E R I L V PS+ L SLSE + F
Sbjct: 609 VPFLVLAVGADNIFIFVLEYQRD-VRRPGEKREEQIGRILGNVAPSMLLCSLSESICFFF 667
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
G+ +MPA + F+++AA+A+LLDF LQ+TAFVAL+ LD +R + R + CIKV
Sbjct: 668 GALSTMPAVKSFALYAAVAILLDFALQMTAFVALLSLDCRRQDSNRCELLCCIKV 722
[169][TOP]
>UniRef100_Q9TT75 Niemann-Pick type C1 disease protein n=1 Tax=Oryctolagus cuniculus
RepID=Q9TT75_RABIT
Length = 1286
Score = 92.4 bits (228), Expect = 1e-17
Identities = 51/113 (45%), Positives = 71/113 (62%), Gaps = 2/113 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV +R L+ ++ L EV PSI L+S +E +AF +G
Sbjct: 699 IPFLVLAVGVDNIFILVQTYQRDERLQGETLDQQLGRVLGEVAPSIFLSSFAETVAFFLG 758
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
MPA FS+FA +AV +DF+LQ+T FV+L+ LD +R E ++D C +
Sbjct: 759 GLSVMPAVHTFSLFAGMAVFIDFLLQITCFVSLLGLDIKRQEKNQLDVLCCFR 811
[170][TOP]
>UniRef100_Q9GLC9 Niemann-Pick type C1 disease protein n=1 Tax=Bos taurus
RepID=Q9GLC9_BOVIN
Length = 1277
Score = 92.4 bits (228), Expect = 1e-17
Identities = 50/112 (44%), Positives = 73/112 (65%), Gaps = 2/112 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILV--HAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV + + + L+ ++ L EV PS+ L+S +E +AF +G
Sbjct: 690 IPFLVLAVGVDNIFILVQTYQIDERLQGETLDQQVGRVLGEVAPSMFLSSFAETVAFFLG 749
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCI 347
MPA FS+FA +AVL+DF+LQ+T FV+L+ LD +R E ++D C+
Sbjct: 750 GLSVMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNQLDVLCCV 801
[171][TOP]
>UniRef100_B4JPL7 GH13378 n=1 Tax=Drosophila grimshawi RepID=B4JPL7_DROGR
Length = 1021
Score = 92.4 bits (228), Expect = 1e-17
Identities = 49/111 (44%), Positives = 71/111 (63%), Gaps = 4/111 (3%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQP--LELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV +R + E ++ L VGPS+ L S+SE F +G
Sbjct: 688 IPFLVLAVGVDNIFILVQTYQRDQRRTDETTEQQVGRVLGHVGPSMLLTSVSESCCFFLG 747
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVD--CF 338
MPA + F+++A +A+L+DF+LQ+T FV L LD++R ++ R+D CF
Sbjct: 748 GLSDMPAVKAFALYAGVALLIDFILQITCFVGLFTLDTKRRDENRLDICCF 798
[172][TOP]
>UniRef100_UPI000180CC29 PREDICTED: Niemann-Pick disease, type C1 n=1 Tax=Ciona intestinalis
RepID=UPI000180CC29
Length = 1366
Score = 92.0 bits (227), Expect = 2e-17
Identities = 52/115 (45%), Positives = 75/115 (65%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILV---HAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
+PFLVLA G DN+ IL +R+P E L +I + EVGPS+ L SL+E +AF +
Sbjct: 732 VPFLVLAIGADNIFILTLEYQRDERKPDE-DLADQIGRVMGEVGPSMLLCSLTECVAFFL 790
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
G+ MPA F++ AA+A+ DF+LQ+TAF+A++ LD++R RVD CIK+
Sbjct: 791 GALTDMPAVEQFALAAAVAIAFDFLLQITAFLAVLSLDARRTRGNRVDVCCCIKM 845
[173][TOP]
>UniRef100_B0WCU9 Niemann-pick C1 n=1 Tax=Culex quinquefasciatus RepID=B0WCU9_CULQU
Length = 1645
Score = 92.0 bits (227), Expect = 2e-17
Identities = 52/108 (48%), Positives = 69/108 (63%), Gaps = 3/108 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR---QPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ILV +R +P E E I L VGPSI L ++SE F +
Sbjct: 904 IPFLVLAVGVDNIFILVQTHQRDTKKPTETHAE-HIGRILGRVGPSILLTAVSESCCFFL 962
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVD 332
G MPA R F+++A +A+L+DF LQ+T FV+L+ LD+ R D R+D
Sbjct: 963 GGLSDMPAVRAFALYAGMALLIDFFLQITCFVSLLALDTARQADNRLD 1010
[174][TOP]
>UniRef100_Q59ZV0 Potential sterol homeostasis protein n=1 Tax=Candida albicans
RepID=Q59ZV0_CANAL
Length = 1256
Score = 92.0 bits (227), Expect = 2e-17
Identities = 48/115 (41%), Positives = 73/115 (63%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVH---AVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA G+DN+ ++VH + L LE RIS AL +GPS ++++ +V F +
Sbjct: 654 IPFLVLAIGIDNIFLIVHELHVISEGNPNLALEVRISQALKHIGPSCFISAVLQVCMFLL 713
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
+ + MPA + F+ + A AVL++F LQ+T F+ L+ LD +R ED RVD P + +
Sbjct: 714 ATSVGMPAVKNFAYYGAGAVLINFSLQMTCFIGLLALDQRRLEDNRVDYVPWVTI 768
[175][TOP]
>UniRef100_C4YFP8 Putative uncharacterized protein n=1 Tax=Candida albicans
RepID=C4YFP8_CANAL
Length = 1256
Score = 92.0 bits (227), Expect = 2e-17
Identities = 48/115 (41%), Positives = 73/115 (63%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVH---AVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA G+DN+ ++VH + L LE RIS AL +GPS ++++ +V F +
Sbjct: 654 IPFLVLAIGIDNIFLIVHELHVISEGNPNLALEVRISQALKHIGPSCFISAVLQVCMFLL 713
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
+ + MPA + F+ + A AVL++F LQ+T F+ L+ LD +R ED RVD P + +
Sbjct: 714 ATSVGMPAVKNFAYYGAGAVLINFSLQMTCFIGLLALDQRRLEDNRVDYVPWVTI 768
[176][TOP]
>UniRef100_B4KJH6 GI18274 (Fragment) n=1 Tax=Drosophila mojavensis RepID=B4KJH6_DROMO
Length = 1253
Score = 91.7 bits (226), Expect = 2e-17
Identities = 49/111 (44%), Positives = 70/111 (63%), Gaps = 4/111 (3%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV +R E ++ L VGPS+ L S+SE F +G
Sbjct: 660 IPFLVLAVGVDNIFILVQTYQRDNRRANETTEKQVGRVLGRVGPSMLLTSVSESCCFFLG 719
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVD--CF 338
S MPA + F+++A +A+L+DF+LQ+T F+ L LD +R ++ R+D CF
Sbjct: 720 SLSDMPAVKAFALYAGVALLIDFILQITCFIGLFTLDIKRKDENRLDICCF 770
[177][TOP]
>UniRef100_Q17FP9 Niemann-pick C1 (Fragment) n=1 Tax=Aedes aegypti RepID=Q17FP9_AEDAE
Length = 1132
Score = 91.3 bits (225), Expect = 3e-17
Identities = 52/108 (48%), Positives = 68/108 (62%), Gaps = 3/108 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR---QPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ILV +R +P E E I L VGPSI L ++SE F +
Sbjct: 396 IPFLVLAVGVDNIFILVQTHQRDTKKPTETHAE-HIGRILGRVGPSILLTAVSESCCFFL 454
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVD 332
G MPA R F+++A +A+L+DF LQ+T FV+L+ LD+ R D R D
Sbjct: 455 GGLSDMPAVRAFALYAGMALLIDFFLQITCFVSLLALDTARQADNRYD 502
[178][TOP]
>UniRef100_B4M8H0 GJ18108 n=1 Tax=Drosophila virilis RepID=B4M8H0_DROVI
Length = 1282
Score = 91.3 bits (225), Expect = 3e-17
Identities = 49/111 (44%), Positives = 69/111 (62%), Gaps = 4/111 (3%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
IPFLVLA GVDN+ ILV +R E ++ L VGPS+ L S+SE F +G
Sbjct: 689 IPFLVLAVGVDNIFILVQTFQRDQRRTNETTEQQVGRVLGRVGPSMLLTSVSESCCFFLG 748
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVD--CF 338
S MPA + F+++A A+L+DF+LQ+T F+ L LD +R ++ R+D CF
Sbjct: 749 SLSDMPAVKAFALYAGAALLIDFILQITCFIGLFTLDIKRKDENRLDICCF 799
[179][TOP]
>UniRef100_A5DNY6 Putative uncharacterized protein n=1 Tax=Pichia guilliermondii
RepID=A5DNY6_PICGU
Length = 1248
Score = 91.3 bits (225), Expect = 3e-17
Identities = 44/115 (38%), Positives = 77/115 (66%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFL+LA G+DN+ +LVH +K+ P +E +S L VGPS ++++ ++ F +
Sbjct: 649 IPFLILAIGIDNIFLLVHELKQVTKSNPSSSVEENVSKTLASVGPSCLISAVLQLTMFLL 708
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
+ + MPA + F+ ++A A+ ++FVLQ+TAFV+L+ LD +R++ R D FP +++
Sbjct: 709 ATVVDMPAVKNFAFYSAGAIFVNFVLQMTAFVSLMTLDQKRSDSGRFDVFPFVQL 763
[180][TOP]
>UniRef100_UPI000151B5B2 hypothetical protein PGUG_04987 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151B5B2
Length = 1248
Score = 90.9 bits (224), Expect = 4e-17
Identities = 45/115 (39%), Positives = 77/115 (66%), Gaps = 3/115 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPL---EGRISNALVEVGPSITLASLSEVLAFAV 188
IPFL+LA G+DN+ +LVH +K+ PL E +S L VGPS ++++ ++ F +
Sbjct: 649 IPFLILAIGIDNIFLLVHELKQVTKSNPLSSVEENVSKTLASVGPSCLISAVLQLTMFLL 708
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
+ + MPA + F+ ++A A+ ++FVLQ+TAFV+L+ LD +R++ R D FP +++
Sbjct: 709 ATVVDMPAVKNFAFYSAGAIFVNFVLQMTAFVSLMTLDQKRSDLGRFDVFPFVQL 763
[181][TOP]
>UniRef100_C4Y974 Putative uncharacterized protein n=1 Tax=Clavispora lusitaniae ATCC
42720 RepID=C4Y974_CLAL4
Length = 1250
Score = 90.5 bits (223), Expect = 5e-17
Identities = 48/117 (41%), Positives = 77/117 (65%), Gaps = 3/117 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAV---KRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ++VH V ++ + RIS + +VGP+ +++L +V F +
Sbjct: 657 IPFLVLAVGVDNVFLIVHEVHLLSESASDISVPERISTGIQKVGPACLISALLQVSVFLL 716
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHS 359
+ + MPA R F++++A A+ ++F+LQ++AFVAL+ LD +R E R+D P I V S
Sbjct: 717 AATVKMPAVRNFALYSAGAIAVNFLLQMSAFVALLSLDQRRLESGRMDLAPWITVQS 773
[182][TOP]
>UniRef100_UPI0000DB761D PREDICTED: similar to Niemann-Pick Type C-1 CG5722-PA isoform 2 n=1
Tax=Apis mellifera RepID=UPI0000DB761D
Length = 1358
Score = 90.1 bits (222), Expect = 7e-17
Identities = 54/121 (44%), Positives = 75/121 (61%), Gaps = 3/121 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQ---PLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ILV +R+ P E + I L +VGPS+ L S+SE F +
Sbjct: 684 IPFLVLAVGVDNIFILVQTHQRESRRPNE-SIPEHIGRILGQVGPSMLLTSVSESCCFFL 742
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHA 368
G MPA + F+++A +A+L+DFVLQVT FV+L+ LD+ R + ++D C VH
Sbjct: 743 GGLSDMPAVKAFALYAGMALLVDFVLQVTCFVSLLALDTIRQANNKLDV--CCFVHGSKK 800
Query: 369 D 371
D
Sbjct: 801 D 801
[183][TOP]
>UniRef100_UPI0001758A11 PREDICTED: similar to niemann-pick C1 n=1 Tax=Tribolium castaneum
RepID=UPI0001758A11
Length = 1306
Score = 89.0 bits (219), Expect = 2e-16
Identities = 52/112 (46%), Positives = 71/112 (63%), Gaps = 5/112 (4%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQ---PLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ ILV +R+ P E + I L +VGPS+ L S+SE F +
Sbjct: 714 IPFLVLAVGVDNIFILVQTHQREGKKPTETHAQ-HIGRTLGQVGPSMLLTSVSESCCFFL 772
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVD--CF 338
GS MPA + F+++A +A+L DF+LQ+T FV+L+ LD+ R R D CF
Sbjct: 773 GSLSDMPAVKAFALYAGMALLFDFLLQITCFVSLLSLDTIRQASNRFDICCF 824
[184][TOP]
>UniRef100_UPI0000E48D84 PREDICTED: similar to Niemann-Pick C disease protein n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000E48D84
Length = 705
Score = 89.0 bits (219), Expect = 2e-16
Identities = 50/121 (41%), Positives = 75/121 (61%), Gaps = 2/121 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLEL--PLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL+LA G DN+ I V +R + E +I L +V PS+ L LSE ++F +G
Sbjct: 46 VPFLILAIGADNIFIYVLDFQRDHRQEGESREEQIGRVLGKVAPSMLLCGLSESISFFLG 105
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHAD 371
+ MPA R+F++++ ++VL++F+LQ+TAFVAL+ LD +R E R D CI H D
Sbjct: 106 ALTEMPAVRIFALYSGMSVLINFILQITAFVALLSLDVRRQESGRFDIVCCIPPK--HKD 163
Query: 372 P 374
P
Sbjct: 164 P 164
[185][TOP]
>UniRef100_UPI00017B10BC UPI00017B10BC related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B10BC
Length = 1362
Score = 89.0 bits (219), Expect = 2e-16
Identities = 44/112 (39%), Positives = 70/112 (62%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL L GVD+M +L H+ + ++PLE R+ N L G SI L S++ + AF + +
Sbjct: 459 LPFLALGIGVDDMFLLAHSFRETGSDIPLEERMGNCLRRTGTSIALTSINNMTAFFMAAI 518
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
+ +PA RVFS+ AA+ V+L+ V+ + F A++ LD R E KR+D C+ +
Sbjct: 519 VPIPALRVFSLQAAIVVVLNLVMVLLIFPAILCLDLYRREAKRLDILCCLYI 570
[186][TOP]
>UniRef100_UPI00017B10BB UPI00017B10BB related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B10BB
Length = 1327
Score = 89.0 bits (219), Expect = 2e-16
Identities = 44/112 (39%), Positives = 70/112 (62%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL L GVD+M +L H+ + ++PLE R+ N L G SI L S++ + AF + +
Sbjct: 466 LPFLALGIGVDDMFLLAHSFRETGSDIPLEERMGNCLRRTGTSIALTSINNMTAFFMAAI 525
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
+ +PA RVFS+ AA+ V+L+ V+ + F A++ LD R E KR+D C+ +
Sbjct: 526 VPIPALRVFSLQAAIVVVLNLVMVLLIFPAILCLDLYRREAKRLDILCCLYI 577
[187][TOP]
>UniRef100_Q4RVD6 Chromosome 15 SCAF14992, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4RVD6_TETNG
Length = 1197
Score = 89.0 bits (219), Expect = 2e-16
Identities = 44/112 (39%), Positives = 70/112 (62%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL L GVD+M +L H+ + ++PLE R+ N L G SI L S++ + AF + +
Sbjct: 518 LPFLALGIGVDDMFLLAHSFRETGSDIPLEERMGNCLRRTGTSIALTSINNMTAFFMAAI 577
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
+ +PA RVFS+ AA+ V+L+ V+ + F A++ LD R E KR+D C+ +
Sbjct: 578 VPIPALRVFSLQAAIVVVLNLVMVLLIFPAILCLDLYRREAKRLDILCCLYI 629
[188][TOP]
>UniRef100_A8PHM2 Patched family protein n=1 Tax=Brugia malayi RepID=A8PHM2_BRUMA
Length = 797
Score = 88.6 bits (218), Expect = 2e-16
Identities = 46/113 (40%), Positives = 70/113 (61%), Gaps = 1/113 (0%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
IPFLVLA GVD++ I +H + LP+E RI L E GPSIT+ SL+ L+FA+ F
Sbjct: 232 IPFLVLAIGVDDVFIFLHCYHQTDPRLPVEERIGKMLAEAGPSITITSLTNFLSFAISIF 291
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCF-PCIKV 353
PA ++FS + ++AV+ D+ Q+ + A++ + R E KR+ F PC+ +
Sbjct: 292 TPTPAIQIFSAYISVAVVFDYTYQIFLYSAILTFGAHR-EKKRLHAFIPCMSI 343
[189][TOP]
>UniRef100_UPI0001924FA3 PREDICTED: similar to predicted protein, partial n=1 Tax=Hydra
magnipapillata RepID=UPI0001924FA3
Length = 1289
Score = 85.9 bits (211), Expect = 1e-15
Identities = 51/112 (45%), Positives = 72/112 (64%), Gaps = 3/112 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVK---RQPLELPLEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA +DN+ ILV A++ R P E E ++ L VGPS+ L+SLSE +AF
Sbjct: 686 IPFLVLAVRIDNIFILVQALQWDDRLPNETVGE-QVGRVLGMVGPSMLLSSLSESVAFGF 744
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
GS + A FS+FAALAV+ +F+LQ+T VA++ LD++R + + D C
Sbjct: 745 GSLSKISAVHTFSIFAALAVVFNFLLQITMLVAVVALDAKRQANNKYDVICC 796
[190][TOP]
>UniRef100_UPI000021CEBE PaTched Related family member (ptr-18) n=1 Tax=Caenorhabditis
elegans RepID=UPI000021CEBE
Length = 858
Score = 85.9 bits (211), Expect = 1e-15
Identities = 39/103 (37%), Positives = 67/103 (65%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL+L+ GVD++ I +HA R P + + R++ L + GPSI++ SL+ +L+FA+G F
Sbjct: 290 VPFLILSIGVDDVFIFIHAWHRTPYKHSVRDRMAETLADAGPSISITSLTNLLSFAIGIF 349
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKR 326
PA F +F + AV+ D++ Q+ F A++VL +R E ++
Sbjct: 350 TPTPAIYTFCVFISTAVIYDYIYQIFFFSAVLVLSGEREEQRK 392
[191][TOP]
>UniRef100_Q9XWL9 Protein Y38F1A.3, partially confirmed by transcript evidence n=1
Tax=Caenorhabditis elegans RepID=Q9XWL9_CAEEL
Length = 895
Score = 85.9 bits (211), Expect = 1e-15
Identities = 39/103 (37%), Positives = 67/103 (65%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL+L+ GVD++ I +HA R P + + R++ L + GPSI++ SL+ +L+FA+G F
Sbjct: 327 VPFLILSIGVDDVFIFIHAWHRTPYKHSVRDRMAETLADAGPSISITSLTNLLSFAIGIF 386
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKR 326
PA F +F + AV+ D++ Q+ F A++VL +R E ++
Sbjct: 387 TPTPAIYTFCVFISTAVIYDYIYQIFFFSAVLVLSGEREEQRK 429
[192][TOP]
>UniRef100_A8IYI0 Sterol sensing domain protein (Fragment) n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IYI0_CHLRE
Length = 717
Score = 85.5 bits (210), Expect = 2e-15
Identities = 53/112 (47%), Positives = 68/112 (60%), Gaps = 3/112 (2%)
Frame = +3
Query: 48 DNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFI-SMPACRVF 224
D + L HA Q LP R++ +L GPSITLA+ E AFA+G + SMPA R F
Sbjct: 260 DAVTSLTHAP--QDHALPPAERLALSLAAAGPSITLAAACETAAFALGGLLTSMPAVRNF 317
Query: 225 SMFAALAVLLDFVLQV--TAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADP 374
S+ AA AV LDF LQV T F AL+VLD +R + +R+DC PCI++ P
Sbjct: 318 SLAAAAAVALDFGLQVQVTVFAALLVLDVRRLQSRRLDCLPCIQLQPEQLQP 369
[193][TOP]
>UniRef100_B7PPF5 Niemann-Pick type C1 domain-containing protein, putative n=1
Tax=Ixodes scapularis RepID=B7PPF5_IXOSC
Length = 1233
Score = 85.5 bits (210), Expect = 2e-15
Identities = 48/116 (41%), Positives = 74/116 (63%), Gaps = 5/116 (4%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEG-----RISNALVEVGPSITLASLSEVLAF 182
IPFLVLA GVDN+ ILV +R ++ EG ++ + EV PS+ L+S+S F
Sbjct: 640 IPFLVLAVGVDNIFILVQQFQR---DVRREGETTVEQVGRLVGEVAPSMMLSSVSMSACF 696
Query: 183 AVGSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIK 350
+G+ PA R+F+++A +A+L++F LQ+T F++L LD+ R ED R+D CI+
Sbjct: 697 FIGALTETPAVRIFALYAGVALLINFFLQMTCFLSLFTLDTLRQEDGRLDLCFCIR 752
[194][TOP]
>UniRef100_A8WPJ5 C. briggsae CBR-PTR-16 protein n=2 Tax=Caenorhabditis briggsae
RepID=A8WPJ5_CAEBR
Length = 808
Score = 85.5 bits (210), Expect = 2e-15
Identities = 39/104 (37%), Positives = 68/104 (65%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL++ G D++ I++HA+++ LE +I+ + E GPSIT+ S + +L+FA+G
Sbjct: 233 MPFLIIGVGCDDVFIIIHAMRKTDKRESLENQIAETMEEAGPSITVTSATNILSFAIGIA 292
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRV 329
PA +F ++ +AV +DFV Q+T FVA++V + +R E R+
Sbjct: 293 TPTPAISLFCLYTCIAVAVDFVYQLTFFVAVLVFEEKRLEAMRL 336
[195][TOP]
>UniRef100_UPI0000E4A6C0 PREDICTED: hypothetical protein n=1 Tax=Strongylocentrotus
purpuratus RepID=UPI0000E4A6C0
Length = 934
Score = 84.3 bits (207), Expect = 4e-15
Identities = 43/121 (35%), Positives = 71/121 (58%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL++ GVDNM I++ ++ + LP+ R+ E SIT+ +L+ +LAF +G+
Sbjct: 355 MPFLIIGVGVDNMFIMIAGWRQLSIYLPVHERMGKTYSEAAVSITITNLTTILAFIIGAS 414
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPD 377
IS+PA R F ++A +A+ + Q+T F A + +R E K + C+ C KV S P+
Sbjct: 415 ISLPAIRAFCIYAGVAMFFAYFYQITFFGACMAFTGER-EAKNLHCYTCKKVVSKDESPN 473
Query: 378 K 380
K
Sbjct: 474 K 474
[196][TOP]
>UniRef100_UPI0000E48CB2 PREDICTED: hypothetical protein n=1 Tax=Strongylocentrotus
purpuratus RepID=UPI0000E48CB2
Length = 842
Score = 84.3 bits (207), Expect = 4e-15
Identities = 43/121 (35%), Positives = 71/121 (58%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL++ GVDNM I++ ++ + LP+ R+ E SIT+ +L+ +LAF +G+
Sbjct: 263 MPFLIIGVGVDNMFIMIAGWRQLSIYLPVHERMGKTYSEAAVSITITNLTTILAFIIGAS 322
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPD 377
IS+PA R F ++A +A+ + Q+T F A + +R E K + C+ C KV S P+
Sbjct: 323 ISLPAIRAFCIYAGVAMFFAYFYQITFFGACMAFTGER-EAKNLHCYTCKKVVSKDESPN 381
Query: 378 K 380
K
Sbjct: 382 K 382
[197][TOP]
>UniRef100_A4S8G2 RND family transporter: Niemann-Pick type C1 disease protein-like
protein n=1 Tax=Ostreococcus lucimarinus CCE9901
RepID=A4S8G2_OSTLU
Length = 808
Score = 84.3 bits (207), Expect = 4e-15
Identities = 39/110 (35%), Positives = 67/110 (60%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL+L GVD+M ++V++ + R+ +L G SIT+ S ++V+AF +GS
Sbjct: 298 LPFLLLGIGVDDMFVIVNSYDNTEARVDPVERMGRSLRVAGMSITVTSATDVIAFLIGSS 357
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCI 347
S+PA + F +AAL + D++ Q+T F A + +D +R + + DCF C+
Sbjct: 358 TSLPALKNFCFYAALGIFFDYLYQITFFTAFLSIDERRKSENKADCFFCL 407
[198][TOP]
>UniRef100_Q6CBA1 YALI0C20757p n=1 Tax=Yarrowia lipolytica RepID=Q6CBA1_YARLI
Length = 1239
Score = 84.3 bits (207), Expect = 4e-15
Identities = 42/101 (41%), Positives = 70/101 (69%), Gaps = 3/101 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELP---LEGRISNALVEVGPSITLASLSEVLAFAV 188
IPFLVLA GVDN+ +L H + + P ++ R+S A+ +GPSI +++++E LAF +
Sbjct: 638 IPFLVLAVGVDNIFLLCHEMDAANIAYPNDSVDTRVSKAVGRIGPSIVISAITETLAFGL 697
Query: 189 GSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQR 311
+ + MPA R F+++AA AV ++ +LQ+T FV+++ LD +R
Sbjct: 698 AATVKMPAVRNFAIYAAGAVFINAILQLTIFVSVMALDQRR 738
[199][TOP]
>UniRef100_A2I5E0 Patched 2 (Fragment) n=1 Tax=Leucoraja erinacea RepID=A2I5E0_RAJER
Length = 386
Score = 84.0 bits (206), Expect = 5e-15
Identities = 43/111 (38%), Positives = 66/111 (59%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD+M +L HA Q +P + R L G S+ L S++ ++AF++
Sbjct: 85 LPFLALGIGVDDMFLLAHAFTETGQNKNIPFKDRTGECLRRTGTSVALTSINNMIAFSMA 144
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ LD R EDKR+D F C
Sbjct: 145 ALIPIPALRAFSLQAAIVVVFNFAMVLLIFPAILSLDLHRREDKRLDIFCC 195
[200][TOP]
>UniRef100_UPI000175F27F PREDICTED: im:7149020, partial n=1 Tax=Danio rerio
RepID=UPI000175F27F
Length = 598
Score = 83.6 bits (205), Expect = 6e-15
Identities = 48/121 (39%), Positives = 72/121 (59%)
Frame = +3
Query: 21 PFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFI 200
P+LVL G D +R P E L +I L +V PS+ L+S SE +AF +G+
Sbjct: 25 PWLVLGGYEDRD-------ERMPEE-ELHQQIGRILGDVAPSMFLSSFSETVAFFLGALS 76
Query: 201 SMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPDK 380
+MPA R FS+FA LA+ +DF+LQ++ FV+L+ LD +R E R+D C+K+ + +
Sbjct: 77 TMPAVRTFSLFAGLAIFIDFLLQISCFVSLLGLDIKRQEANRMDILCCVKLSDGQEEKSE 136
Query: 381 G 383
G
Sbjct: 137 G 137
[201][TOP]
>UniRef100_Q9DEF3 Patched-2 n=1 Tax=Xenopus laevis RepID=Q9DEF3_XENLA
Length = 1413
Score = 83.6 bits (205), Expect = 6e-15
Identities = 41/109 (37%), Positives = 64/109 (58%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL L GVD+M +L HA P + R L G S+TL S++ ++AF + +
Sbjct: 484 LPFLALGIGVDDMFLLAHAFTETSRSTPFKDRTGECLRRTGTSVTLTSINNMIAFFMAAL 543
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ +PA R FS+ AA+ V+ +F + + F A++ LD QR ED+R+D C
Sbjct: 544 VPIPALRAFSLQAAVIVVFNFAMVLLIFPAILSLDLQRREDQRLDILCC 592
[202][TOP]
>UniRef100_C3SAR5 Patched 2 (Fragment) n=1 Tax=Scyliorhinus canicula
RepID=C3SAR5_SCYCA
Length = 385
Score = 83.6 bits (205), Expect = 6e-15
Identities = 43/111 (38%), Positives = 65/111 (58%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD+M +L HA Q +P + R L G S+ L S++ ++AF +
Sbjct: 85 LPFLALGIGVDDMFLLAHAFTETGQNKNIPFKDRTGECLRRTGTSVALTSINNIIAFFMA 144
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ LD R EDKR+D F C
Sbjct: 145 ALIPIPALRAFSLQAAIVVVFNFAMVLLIFPAILSLDLHRREDKRLDIFCC 195
[203][TOP]
>UniRef100_Q9Z2A1 Patched (Fragment) n=1 Tax=Rattus norvegicus RepID=Q9Z2A1_RAT
Length = 608
Score = 83.2 bits (204), Expect = 8e-15
Identities = 43/111 (38%), Positives = 65/111 (58%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P+E R L G S+ L S+S V AF +
Sbjct: 489 LPFLALGVGVDDVFLLAHAFSETGQNKRIPIEDRTGECLKRTGASVALTSISNVTAFFMA 548
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED+R+D F C
Sbjct: 549 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 599
[204][TOP]
>UniRef100_UPI0000F2D9E2 PREDICTED: similar to patched homolog 1 (Drosophila) n=1
Tax=Monodelphis domestica RepID=UPI0000F2D9E2
Length = 1724
Score = 82.8 bits (203), Expect = 1e-14
Identities = 43/111 (38%), Positives = 64/111 (57%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 780 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 839
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED+R+D F C
Sbjct: 840 ALIPIPALRAFSLQAAIVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 890
[205][TOP]
>UniRef100_UPI00002231DA Hypothetical protein CBG02766 n=1 Tax=Caenorhabditis briggsae AF16
RepID=UPI00002231DA
Length = 798
Score = 82.8 bits (203), Expect = 1e-14
Identities = 43/129 (33%), Positives = 77/129 (59%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL+L+ GVD++ I +HA R P + + R++ L + GPSI++ SL+ +L+F +G F
Sbjct: 232 VPFLILSIGVDDVFIFIHAWHRTPHKHSVRDRMAETLADAGPSISITSLTNLLSFGIGIF 291
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPD 377
PA F +F + AV+ D++ Q+ F A++VL R E++R++ + K +P
Sbjct: 292 TPTPAIYTFCVFISTAVIYDYIYQIFFFSAVLVLGGDR-EERRMNAYFWWKYEPLKEEPK 350
Query: 378 KGIRQRKPG 404
+++K G
Sbjct: 351 N--KKKKDG 357
[206][TOP]
>UniRef100_B7T1N0 Niemann-Pick C1-like protein 1 (Fragment) n=1 Tax=Monodelphis
domestica RepID=B7T1N0_MONDO
Length = 270
Score = 82.8 bits (203), Expect = 1e-14
Identities = 47/97 (48%), Positives = 62/97 (63%), Gaps = 2/97 (2%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPL--ELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFLVLA G DN+ I V +R P E E I L V PS+ L SLSE + F +G
Sbjct: 174 VPFLVLAVGADNIFIFVLEYQRLPRHSEESREVHIGRVLGTVAPSMLLCSLSEAICFFLG 233
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLD 302
+ SMPA R F++ A LA++ DF+LQ++AFVAL+ LD
Sbjct: 234 ALTSMPAVRTFALTAGLAIIFDFLLQMSAFVALLSLD 270
[207][TOP]
>UniRef100_C3YCG9 Putative uncharacterized protein (Fragment) n=1 Tax=Branchiostoma
floridae RepID=C3YCG9_BRAFL
Length = 664
Score = 82.8 bits (203), Expect = 1e-14
Identities = 44/126 (34%), Positives = 72/126 (57%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
IPFL+L GVD+M +++ A ++ + LP++ R+ A+ + G SIT+ S+++ LAF G
Sbjct: 139 IPFLLLGIGVDDMFVMIAAWRKCDVTLPVQERMGRAMSDAGVSITITSITDCLAFVAGVM 198
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPD 377
P+ R+F ++A++ V DF+ Q+T F A + L +R R CF C+ V D
Sbjct: 199 NVFPSVRLFCIYASVGVAFDFLYQITFFAAFMSLTGRRERANR-HCFTCLPVLPKSQAQD 257
Query: 378 KGIRQR 395
K R
Sbjct: 258 KSAAYR 263
[208][TOP]
>UniRef100_A8WTK0 C. briggsae CBR-PTR-18 protein n=1 Tax=Caenorhabditis briggsae
RepID=A8WTK0_CAEBR
Length = 905
Score = 82.8 bits (203), Expect = 1e-14
Identities = 43/129 (33%), Positives = 77/129 (59%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL+L+ GVD++ I +HA R P + + R++ L + GPSI++ SL+ +L+F +G F
Sbjct: 339 VPFLILSIGVDDVFIFIHAWHRTPHKHSVRDRMAETLADAGPSISITSLTNLLSFGIGIF 398
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADPD 377
PA F +F + AV+ D++ Q+ F A++VL R E++R++ + K +P
Sbjct: 399 TPTPAIYTFCVFISTAVIYDYIYQIFFFSAVLVLGGDR-EERRMNAYFWWKYEPLKEEPK 457
Query: 378 KGIRQRKPG 404
+++K G
Sbjct: 458 N--KKKKDG 464
[209][TOP]
>UniRef100_UPI000194DF4B PREDICTED: patched n=1 Tax=Taeniopygia guttata RepID=UPI000194DF4B
Length = 1443
Score = 82.4 bits (202), Expect = 1e-14
Identities = 43/111 (38%), Positives = 64/111 (57%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 503 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 562
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED+R+D F C
Sbjct: 563 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 613
[210][TOP]
>UniRef100_UPI000179784D PREDICTED: patched n=1 Tax=Equus caballus RepID=UPI000179784D
Length = 1395
Score = 82.4 bits (202), Expect = 1e-14
Identities = 43/111 (38%), Positives = 64/111 (57%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 446 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 505
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED+R+D F C
Sbjct: 506 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 556
[211][TOP]
>UniRef100_UPI0000D9E037 PREDICTED: similar to patched n=1 Tax=Macaca mulatta
RepID=UPI0000D9E037
Length = 801
Score = 82.4 bits (202), Expect = 1e-14
Identities = 43/111 (38%), Positives = 64/111 (57%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 433 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 492
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED+R+D F C
Sbjct: 493 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 543
[212][TOP]
>UniRef100_UPI0000F58F24 patched isoform L'''' n=1 Tax=Homo sapiens RepID=UPI0000F58F24
Length = 1446
Score = 82.4 bits (202), Expect = 1e-14
Identities = 43/111 (38%), Positives = 64/111 (57%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 502 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 561
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED+R+D F C
Sbjct: 562 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 612
[213][TOP]
>UniRef100_Q3LFT4 PTCH protein-10 (Fragment) n=2 Tax=Homo sapiens RepID=Q3LFT4_HUMAN
Length = 348
Score = 82.4 bits (202), Expect = 1e-14
Identities = 43/111 (38%), Positives = 64/111 (57%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 164 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 223
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED+R+D F C
Sbjct: 224 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 274
[214][TOP]
>UniRef100_Q5VZC2 Patched homolog 1 (Drosophila) n=2 Tax=Homo sapiens
RepID=Q5VZC2_HUMAN
Length = 1296
Score = 82.4 bits (202), Expect = 1e-14
Identities = 43/111 (38%), Positives = 64/111 (57%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 352 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 411
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED+R+D F C
Sbjct: 412 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 462
[215][TOP]
>UniRef100_UPI0000EB47AC Protein patched homolog 1 (PTC1) (PTC). n=1 Tax=Canis lupus
familiaris RepID=UPI0000EB47AC
Length = 1454
Score = 82.4 bits (202), Expect = 1e-14
Identities = 43/111 (38%), Positives = 64/111 (57%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 506 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 565
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED+R+D F C
Sbjct: 566 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 616
[216][TOP]
>UniRef100_UPI0000EBCDA7 PREDICTED: patched homolog 1 (Drosophila) n=1 Tax=Bos taurus
RepID=UPI0000EBCDA7
Length = 1453
Score = 82.4 bits (202), Expect = 1e-14
Identities = 43/111 (38%), Positives = 64/111 (57%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 502 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 561
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED+R+D F C
Sbjct: 562 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 612
[217][TOP]
>UniRef100_UPI0000ECC273 Protein patched homolog 1 (PTC1) (PTC). n=1 Tax=Gallus gallus
RepID=UPI0000ECC273
Length = 1303
Score = 82.4 bits (202), Expect = 1e-14
Identities = 43/111 (38%), Positives = 64/111 (57%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 372 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 431
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED+R+D F C
Sbjct: 432 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 482
[218][TOP]
>UniRef100_Q6UY90 Patched n=1 Tax=Rattus norvegicus RepID=Q6UY90_RAT
Length = 1434
Score = 82.4 bits (202), Expect = 1e-14
Identities = 43/111 (38%), Positives = 64/111 (57%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 489 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 548
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED+R+D F C
Sbjct: 549 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 599
[219][TOP]
>UniRef100_Q3UUD4 Putative uncharacterized protein (Fragment) n=1 Tax=Mus musculus
RepID=Q3UUD4_MOUSE
Length = 247
Score = 82.4 bits (202), Expect = 1e-14
Identities = 43/111 (38%), Positives = 64/111 (57%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 103 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 162
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED+R+D F C
Sbjct: 163 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 213
[220][TOP]
>UniRef100_Q61115 Protein patched homolog 1 n=1 Tax=Mus musculus RepID=PTC1_MOUSE
Length = 1434
Score = 82.4 bits (202), Expect = 1e-14
Identities = 43/111 (38%), Positives = 64/111 (57%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 489 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 548
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED+R+D F C
Sbjct: 549 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 599
[221][TOP]
>UniRef100_Q13635 Protein patched homolog 1 n=1 Tax=Homo sapiens RepID=PTC1_HUMAN
Length = 1447
Score = 82.4 bits (202), Expect = 1e-14
Identities = 43/111 (38%), Positives = 64/111 (57%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 503 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 562
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED+R+D F C
Sbjct: 563 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 613
[222][TOP]
>UniRef100_Q90693 Protein patched homolog 1 n=1 Tax=Gallus gallus RepID=PTC1_CHICK
Length = 1442
Score = 82.4 bits (202), Expect = 1e-14
Identities = 43/111 (38%), Positives = 64/111 (57%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 503 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 562
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED+R+D F C
Sbjct: 563 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 613
[223][TOP]
>UniRef100_UPI00018660BE hypothetical protein BRAFLDRAFT_126548 n=1 Tax=Branchiostoma
floridae RepID=UPI00018660BE
Length = 945
Score = 82.0 bits (201), Expect = 2e-14
Identities = 39/112 (34%), Positives = 69/112 (61%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL++ GVD+M +++ A ++ + LP++ R+ A+ + SIT+ S+++ +AFAVG
Sbjct: 317 VPFLLIGVGVDDMFVMIAAWRKCDVRLPVQERMGRAMSDAAASITITSITDCVAFAVGVI 376
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
P+ R+F +AA+ V D++ Q+T F A++ L +R R CF C V
Sbjct: 377 SVFPSVRIFCTYAAIGVAFDYLYQITFFAAIMSLAGRRERANR-HCFTCCPV 427
[224][TOP]
>UniRef100_UPI000069FEA0 Protein patched homolog 2 (PTC2). n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069FEA0
Length = 1415
Score = 82.0 bits (201), Expect = 2e-14
Identities = 40/109 (36%), Positives = 63/109 (57%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL L GVD+M +L HA L P + R L G S+ L S++ ++AF + +
Sbjct: 484 LPFLALGIGVDDMFLLAHAFTETSLSTPFKERTGECLRRTGTSVALTSINNMIAFFMAAL 543
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ +PA R FS+ AA+ V+ +F + + F A++ LD R ED+R+D C
Sbjct: 544 VPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSLDLHRREDQRLDILCC 592
[225][TOP]
>UniRef100_Q6IRA5 Putative uncharacterized protein n=1 Tax=Xenopus laevis
RepID=Q6IRA5_XENLA
Length = 1422
Score = 82.0 bits (201), Expect = 2e-14
Identities = 40/109 (36%), Positives = 63/109 (57%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL L GVD+M +L HA L P + R L G S+ L S++ ++AF + +
Sbjct: 484 LPFLALGIGVDDMFLLAHAFTETSLSTPFKERTGECLRRTGTSVALTSINNMIAFFMAAL 543
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ +PA R FS+ AA+ V+ +F + + F A++ LD R ED+R+D C
Sbjct: 544 VPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSLDLHRREDQRLDILCC 592
[226][TOP]
>UniRef100_O16307 Patched related family protein 16 n=1 Tax=Caenorhabditis elegans
RepID=O16307_CAEEL
Length = 881
Score = 82.0 bits (201), Expect = 2e-14
Identities = 40/112 (35%), Positives = 70/112 (62%), Gaps = 7/112 (6%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL++ G D++ I++HA+++ LE RI+ + E GPSIT+ S + L+FA+G
Sbjct: 248 MPFLIIGVGCDDVFIIIHAMRKTDKSESLEDRIAETMEEAGPSITVTSATNCLSFAIGIA 307
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQR-------AEDKRVD 332
PA +F ++ +AV +DFV Q+T FVA++V + +R E+K+++
Sbjct: 308 TPTPAISLFCLYTCVAVAVDFVYQLTFFVAVLVYEEKRLMKLQKVGEEKKIE 359
[227][TOP]
>UniRef100_C3YCH2 Putative uncharacterized protein (Fragment) n=1 Tax=Branchiostoma
floridae RepID=C3YCH2_BRAFL
Length = 840
Score = 82.0 bits (201), Expect = 2e-14
Identities = 39/112 (34%), Positives = 69/112 (61%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL++ GVD+M +++ A ++ + LP++ R+ A+ + SIT+ S+++ +AFAVG
Sbjct: 317 VPFLLIGVGVDDMFVMIAAWRKCDVRLPVQERMGRAMSDAAASITITSITDCVAFAVGVI 376
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
P+ R+F +AA+ V D++ Q+T F A++ L +R R CF C V
Sbjct: 377 SVFPSVRIFCTYAAIGVAFDYLYQITFFAAIMSLAGRRERANR-HCFTCCPV 427
[228][TOP]
>UniRef100_B3RI30 Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens
RepID=B3RI30_TRIAD
Length = 978
Score = 82.0 bits (201), Expect = 2e-14
Identities = 47/120 (39%), Positives = 69/120 (57%), Gaps = 8/120 (6%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILV--------HAVKRQPLELPLEGRISNALVEVGPSITLASLSEV 173
+PFL+L GVD+M ++ HA R + + L + G SIT+ SL++V
Sbjct: 339 LPFLLLGIGVDDMFVIATAWDNFKHHAGDRT---VDIAEHAGQCLKKAGVSITVTSLTDV 395
Query: 174 LAFAVGSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
+AF +G+ +PA FS+FA + +L F+LQ+T F A IVLDS+R R C PC+KV
Sbjct: 396 VAFTIGASTVLPALSSFSIFAGIGILAVFILQITFFTACIVLDSRRRNAGRDACLPCLKV 455
[229][TOP]
>UniRef100_UPI0000568152 PREDICTED: patched2 n=1 Tax=Danio rerio RepID=UPI0000568152
Length = 1242
Score = 81.6 bits (200), Expect = 2e-14
Identities = 43/111 (38%), Positives = 63/111 (56%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 492 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 551
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED+R D F C
Sbjct: 552 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRFDIFCC 602
[230][TOP]
>UniRef100_B0UXP5 Patched 2 (Fragment) n=2 Tax=Danio rerio RepID=B0UXP5_DANRE
Length = 1354
Score = 81.6 bits (200), Expect = 2e-14
Identities = 43/111 (38%), Positives = 63/111 (56%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 371 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 430
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED+R D F C
Sbjct: 431 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRFDIFCC 481
[231][TOP]
>UniRef100_UPI00016E939F UPI00016E939F related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E939F
Length = 1147
Score = 81.6 bits (200), Expect = 2e-14
Identities = 43/111 (38%), Positives = 63/111 (56%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 430 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 489
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED+R D F C
Sbjct: 490 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRFDIFCC 540
[232][TOP]
>UniRef100_UPI00016E939E UPI00016E939E related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E939E
Length = 1458
Score = 81.6 bits (200), Expect = 2e-14
Identities = 43/111 (38%), Positives = 63/111 (56%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 493 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 552
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED+R D F C
Sbjct: 553 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRFDIFCC 603
[233][TOP]
>UniRef100_UPI00016E939D UPI00016E939D related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E939D
Length = 1448
Score = 81.6 bits (200), Expect = 2e-14
Identities = 43/111 (38%), Positives = 63/111 (56%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 493 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 552
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED+R D F C
Sbjct: 553 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRFDIFCC 603
[234][TOP]
>UniRef100_Q9W6T6 Patched-2 protein n=1 Tax=Danio rerio RepID=Q9W6T6_DANRE
Length = 1243
Score = 81.6 bits (200), Expect = 2e-14
Identities = 43/111 (38%), Positives = 63/111 (56%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 492 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVVLTSISNVTAFFMA 551
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED+R D F C
Sbjct: 552 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRFDIFCC 602
[235][TOP]
>UniRef100_A7SH24 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7SH24_NEMVE
Length = 881
Score = 81.6 bits (200), Expect = 2e-14
Identities = 39/109 (35%), Positives = 69/109 (63%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL+L G+D+M ILV + RQ +L + I + G ++T+ ++++++AFAV +
Sbjct: 321 LPFLILGIGIDDMFILVDELDRQDNKLSVIDTIKMVMRHSGMTVTMTTVTDLVAFAVSTS 380
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ P+ R F ++AAL+V L +++ +T FVA+ D +R + R DC PC
Sbjct: 381 TAFPSIRYFCIYAALSVTLSYLMIITYFVAIATFDVRRIKANRRDCLPC 429
[236][TOP]
>UniRef100_A7SAU6 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7SAU6_NEMVE
Length = 644
Score = 81.6 bits (200), Expect = 2e-14
Identities = 39/109 (35%), Positives = 69/109 (63%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL+L G+D+M ILV + RQ +L + I + G ++T+ ++++++AFAV +
Sbjct: 140 LPFLILGIGIDDMFILVDELDRQDNKLSVIDTIKMVMRHSGMTVTMTTVTDLVAFAVSTS 199
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ P+ R F ++AAL+V L +++ +T FVA+ D +R + R DC PC
Sbjct: 200 TAFPSIRYFCIYAALSVTLSYLMIITYFVAIATFDVRRIKANRRDCLPC 248
[237][TOP]
>UniRef100_UPI0001A2D58B Protein patched homolog 1 (Patched 1) (PTC1). n=1 Tax=Danio rerio
RepID=UPI0001A2D58B
Length = 1221
Score = 81.3 bits (199), Expect = 3e-14
Identities = 39/109 (35%), Positives = 64/109 (58%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL L GVD+M +L H+ +P + R + L G S+ L S++ ++AF + +
Sbjct: 486 LPFLALGIGVDDMFLLAHSFTETRSNIPFKERTGDCLRRTGTSVALTSINNMIAFFMAAL 545
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ +PA R FS+ AA+ V+ +F + + F A++ LD R EDKR+D C
Sbjct: 546 VPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSLDLHRREDKRLDILCC 594
[238][TOP]
>UniRef100_Q6TKP9 Patched (Fragment) n=1 Tax=Homo sapiens RepID=Q6TKP9_HUMAN
Length = 651
Score = 81.3 bits (199), Expect = 3e-14
Identities = 42/111 (37%), Positives = 64/111 (57%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 98 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 157
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ ++ +F + + F A++ +D R ED+R+D F C
Sbjct: 158 ALIPIPALRAFSLQAAVVLVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 208
[239][TOP]
>UniRef100_UPI00015B5B0C PREDICTED: similar to conserved hypothetical protein n=1
Tax=Nasonia vitripennis RepID=UPI00015B5B0C
Length = 957
Score = 80.9 bits (198), Expect = 4e-14
Identities = 41/116 (35%), Positives = 72/116 (62%), Gaps = 5/116 (4%)
Frame = +3
Query: 15 NIPFLVLAGGVDNMCILVHAVKR-----QPLELPLEGRISNALVEVGPSITLASLSEVLA 179
++PF+++ GVD+ +++ A + + + PL R++ AL G +I++ SL++V+A
Sbjct: 403 SLPFMLMGLGVDDTFVMMAAWEEVISHEKNRDKPLPERVALALSHAGAAISVTSLTDVVA 462
Query: 180 FAVGSFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCI 347
F +G+ +P+ F ++AA+ V + F+LQVT FVA LD QR E+KR PC+
Sbjct: 463 FVIGASTILPSLHSFCIYAAVGVFVTFILQVTFFVAFFTLDCQRVENKRNGVLPCV 518
[240][TOP]
>UniRef100_Q00U42 Novel protein (ISS) (Fragment) n=1 Tax=Ostreococcus tauri
RepID=Q00U42_OSTTA
Length = 853
Score = 80.9 bits (198), Expect = 4e-14
Identities = 40/110 (36%), Positives = 65/110 (59%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL+L GVD+M ++V+A + R+ L G S+T+ S+++V+AF +GS
Sbjct: 375 LPFLLLGVGVDDMFVIVNAYDNVEARVDPVERMGRTLRYAGMSVTVTSITDVIAFLIGSS 434
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCI 347
S+PA + F +AAL + D+ QVT F A + LD +R ++ D F C+
Sbjct: 435 TSLPALKNFCYYAALGIFFDYFYQVTFFTACVALDERRKAKRQGDVFCCL 484
[241][TOP]
>UniRef100_Q5EFR6 Patched-1 (Fragment) n=1 Tax=Ambystoma mexicanum RepID=Q5EFR6_AMBME
Length = 493
Score = 80.5 bits (197), Expect = 5e-14
Identities = 43/111 (38%), Positives = 63/111 (56%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 378 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 437
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R ED R+D F C
Sbjct: 438 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDCRLDIFCC 488
[242][TOP]
>UniRef100_A8I9H8 Sterol sensing 5-transmembrane protein n=1 Tax=Chlamydomonas
reinhardtii RepID=A8I9H8_CHLRE
Length = 905
Score = 80.5 bits (197), Expect = 5e-14
Identities = 40/98 (40%), Positives = 65/98 (66%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL++ GVDN ++V Q + P+E R+ A+ G SIT++ L+ V+AFAVG++
Sbjct: 256 LPFLLVGVGVDNTFVIVSNYFDQDPDAPIEHRLGEAMALGGSSITVSCLTNVIAFAVGTY 315
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQR 311
S+ A FS++A++ VL+ F+ QVT F A + LD++R
Sbjct: 316 TSLEALLSFSVYASIGVLMVFIFQVTTFPAFLALDARR 353
[243][TOP]
>UniRef100_C3Z0Q6 Putative uncharacterized protein (Fragment) n=1 Tax=Branchiostoma
floridae RepID=C3Z0Q6_BRAFL
Length = 845
Score = 80.5 bits (197), Expect = 5e-14
Identities = 42/110 (38%), Positives = 64/110 (58%), Gaps = 2/110 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFLV+ GVDNM IL+ A +R +E R ++ E G SIT+ +++ LAFAVG+
Sbjct: 326 MPFLVIGVGVDNMFILLAAWRRTSPRRSVEERAADTFTEAGVSITITAMTNALAFAVGAI 385
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKR--VDCFP 341
S P R+F M++ +AVL ++ Q+ F A ++ D R R + C P
Sbjct: 386 TSFPGVRIFCMYSGVAVLFAYLFQINFFGACLIYDGIREHQNRHFLTCLP 435
[244][TOP]
>UniRef100_A8NFV7 Patched family protein n=1 Tax=Brugia malayi RepID=A8NFV7_BRUMA
Length = 866
Score = 80.5 bits (197), Expect = 5e-14
Identities = 41/117 (35%), Positives = 70/117 (59%)
Frame = +3
Query: 24 FLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIS 203
FLVL+ GVD++ I++ A R + P+ R++ L GPSIT++SL+ L+F +G F S
Sbjct: 308 FLVLSVGVDDVFIILRAWDRISIATPIPERLAKTLENAGPSITISSLTNALSFGIGIFSS 367
Query: 204 MPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKVHSFHADP 374
PA R FS+++ A+++ + Q+ F A++ + +R ++ F C+K ADP
Sbjct: 368 TPAVRTFSIYSCFAIIVCYFFQLILFTAVLAVSGKREQNNYQALFCCLK-----ADP 419
[245][TOP]
>UniRef100_Q4PE83 Putative uncharacterized protein n=1 Tax=Ustilago maydis
RepID=Q4PE83_USTMA
Length = 1489
Score = 80.1 bits (196), Expect = 7e-14
Identities = 36/83 (43%), Positives = 58/83 (69%)
Frame = +3
Query: 102 LEGRISNALVEVGPSITLASLSEVLAFAVGSFISMPACRVFSMFAALAVLLDFVLQVTAF 281
+E R + +L VGPSI L++ ++++AF +G+ + MPA R F+++AA ++L+ VL T F
Sbjct: 890 VEERAARSLARVGPSILLSATTQIVAFLLGAVVPMPAVRNFALYAAGSMLIVAVLHCTVF 949
Query: 282 VALIVLDSQRAEDKRVDCFPCIK 350
+A + LD+ R E R+DC PCIK
Sbjct: 950 IAAMALDAHRVESGRIDCMPCIK 972
[246][TOP]
>UniRef100_UPI000069F063 Protein patched homolog 1 (PTC1) (PTC). n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069F063
Length = 1424
Score = 79.0 bits (193), Expect = 2e-13
Identities = 42/111 (37%), Positives = 63/111 (56%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 497 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 556
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R E +R+D F C
Sbjct: 557 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREVRRLDIFCC 607
[247][TOP]
>UniRef100_Q98SW6 Patched-1 n=2 Tax=Xenopus laevis RepID=Q98SW6_XENLA
Length = 1418
Score = 79.0 bits (193), Expect = 2e-13
Identities = 42/111 (37%), Positives = 63/111 (56%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 493 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 552
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + F A++ +D R E +R+D F C
Sbjct: 553 ALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREVRRLDIFCC 603
[248][TOP]
>UniRef100_Q2MHN4 Patched n=1 Tax=Meriones unguiculatus RepID=Q2MHN4_MERUN
Length = 1434
Score = 79.0 bits (193), Expect = 2e-13
Identities = 42/111 (37%), Positives = 62/111 (55%), Gaps = 2/111 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKR--QPLELPLEGRISNALVEVGPSITLASLSEVLAFAVG 191
+PFL L GVD++ +L HA Q +P E R L G S+ L S+S V AF +
Sbjct: 489 LPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMA 548
Query: 192 SFISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPC 344
+ I +PA R FS+ AA+ V+ +F + + A++ +D R ED+R D F C
Sbjct: 549 ALIPIPALRAFSLQAAVVVVFNFAMVLLILPAILSMDLYRREDRRSDIFCC 599
[249][TOP]
>UniRef100_C3ZGC3 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
RepID=C3ZGC3_BRAFL
Length = 772
Score = 79.0 bits (193), Expect = 2e-13
Identities = 41/110 (37%), Positives = 64/110 (58%), Gaps = 2/110 (1%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFLV+ GVDNM IL+ + +R +E R ++ E G SIT+ +++ LAFAVG+
Sbjct: 327 MPFLVIGVGVDNMFILLASWRRTSPRHSVEERAADTFTEAGVSITITAMTNALAFAVGAI 386
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKR--VDCFP 341
S P R+F M++ +AVL ++ Q+ F A ++ D R R + C P
Sbjct: 387 TSFPGVRIFCMYSGVAVLFAYLFQINFFGACLIYDGIREHQNRHFLTCLP 436
[250][TOP]
>UniRef100_C3YPF1 Putative uncharacterized protein (Fragment) n=1 Tax=Branchiostoma
floridae RepID=C3YPF1_BRAFL
Length = 743
Score = 79.0 bits (193), Expect = 2e-13
Identities = 41/112 (36%), Positives = 69/112 (61%)
Frame = +3
Query: 18 IPFLVLAGGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSF 197
+PFL+L GVD+M I++ + ++ L + R +AL + +IT+ SL++ +AFAVG+
Sbjct: 221 VPFLLLGIGVDDMFIMIASWRKTDSRLAVPERTGHALADAATAITITSLTDCVAFAVGTI 280
Query: 198 ISMPACRVFSMFAALAVLLDFVLQVTAFVALIVLDSQRAEDKRVDCFPCIKV 353
PA R+F ++AA+ V D+V Q+T F A++ L +R + R C+KV
Sbjct: 281 TVFPAVRIFCIYAAVGVAFDYVYQITFFAAILSLAGRREKAGR-HWLTCLKV 331