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[1][TOP]
>UniRef100_C6T731 Methylenetetrahydrofolate reductase n=1 Tax=Glycine max
RepID=C6T731_SOYBN
Length = 344
Score = 241 bits (615), Expect = 2e-62
Identities = 118/138 (85%), Positives = 127/138 (92%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MK+IEKIH AA++DPN+VVFSFEFFPPKTEDGV NL ERMDRMV H+PSF DITW AGG+
Sbjct: 1 MKIIEKIH-AASADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVVHNPSFCDITWSAGGT 59
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
TAD+TL+IA KMQN V VETMMHLTCTNMPVEKID AL TIKSNGLQNVLALRGDPPHGQ
Sbjct: 60 TADLTLEIANKMQNIVCVETMMHLTCTNMPVEKIDHALHTIKSNGLQNVLALRGDPPHGQ 119
Query: 439 DKFVQVEGGFACARDLVK 492
DKFVQVEGGFACARDLV+
Sbjct: 120 DKFVQVEGGFACARDLVQ 137
[2][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 236 bits (602), Expect = 6e-61
Identities = 119/150 (79%), Positives = 126/150 (84%), Gaps = 12/150 (8%)
Frame = +1
Query: 79 MKVIEKIHEAAA------------SDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSP 222
MKVI+KI EAA S NKVVFSFEFFPPKTEDGV NL ERMDRMVAH+P
Sbjct: 1 MKVIDKIREAAGGGGDANGNGGDNSSSNKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNP 60
Query: 223 SFXDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQN 402
SF DITWGAGGSTAD+TLDIA KMQN + VETMMHLTCTNMPVEKID ALETIKSNG+QN
Sbjct: 61 SFCDITWGAGGSTADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQN 120
Query: 403 VLALRGDPPHGQDKFVQVEGGFACARDLVK 492
VLALRGDPPHGQDKFVQ++GGFACA DLVK
Sbjct: 121 VLALRGDPPHGQDKFVQIQGGFACALDLVK 150
[3][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 231 bits (590), Expect = 1e-59
Identities = 116/147 (78%), Positives = 125/147 (85%), Gaps = 9/147 (6%)
Frame = +1
Query: 79 MKVIEKIHEAAA---------SDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFX 231
MKVI+KI AAA S NKVVFSFEFFPPKT+DGV NL ERMDRMV+H+PSF
Sbjct: 1 MKVIDKIRAAAAAGDSNGGDSSSNNKVVFSFEFFPPKTDDGVDNLFERMDRMVSHNPSFC 60
Query: 232 DITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLA 411
DITWGAGGSTAD+TLDIA KMQN + VETMMHLTCTNMPVEKID ALETIKSNG+QNVLA
Sbjct: 61 DITWGAGGSTADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLA 120
Query: 412 LRGDPPHGQDKFVQVEGGFACARDLVK 492
LRGDPPHGQDKFVQ++GG ACA DLVK
Sbjct: 121 LRGDPPHGQDKFVQIQGGLACALDLVK 147
[4][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 231 bits (588), Expect = 2e-59
Identities = 112/138 (81%), Positives = 124/138 (89%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MKVIEKI +AA + KVVFSFEFFPPKTEDGV NL ERMDRMVAH P+F DITWGAGGS
Sbjct: 1 MKVIEKIRDAATEE-GKVVFSFEFFPPKTEDGVDNLFERMDRMVAHGPAFCDITWGAGGS 59
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
TAD+TL+I+ KMQN + VETMMHLTCTNMPVEKID AL+TIKSNG+QNVLALRGDPPHGQ
Sbjct: 60 TADLTLEISNKMQNMICVETMMHLTCTNMPVEKIDHALDTIKSNGIQNVLALRGDPPHGQ 119
Query: 439 DKFVQVEGGFACARDLVK 492
DKFVQ++GGFACA DLV+
Sbjct: 120 DKFVQIQGGFACALDLVQ 137
[5][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 231 bits (588), Expect = 2e-59
Identities = 112/138 (81%), Positives = 124/138 (89%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MKVIEKI +AA + KVVFSFEFFPPKTEDGV NL ERMDRMVAH P+F DITWGAGGS
Sbjct: 1 MKVIEKIRDAATEE-GKVVFSFEFFPPKTEDGVDNLFERMDRMVAHGPAFCDITWGAGGS 59
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
TAD+TL+I+ KMQN + VETMMHLTCTNMPVEKID AL+TIKSNG+QNVLALRGDPPHGQ
Sbjct: 60 TADLTLEISNKMQNMICVETMMHLTCTNMPVEKIDHALDTIKSNGIQNVLALRGDPPHGQ 119
Query: 439 DKFVQVEGGFACARDLVK 492
DKFVQ++GGFACA DLV+
Sbjct: 120 DKFVQIQGGFACALDLVQ 137
[6][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 231 bits (588), Expect = 2e-59
Identities = 112/138 (81%), Positives = 124/138 (89%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MKVIEKI +AA + KVVFSFEFFPPKTEDGV NL ERMDRMVAH P+F DITWGAGGS
Sbjct: 1 MKVIEKIRDAATEE-GKVVFSFEFFPPKTEDGVDNLFERMDRMVAHGPAFCDITWGAGGS 59
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
TAD+TL+I+ KMQN + VETMMHLTCTNMPVEKID AL+TIKSNG+QNVLALRGDPPHGQ
Sbjct: 60 TADLTLEISNKMQNMICVETMMHLTCTNMPVEKIDHALDTIKSNGIQNVLALRGDPPHGQ 119
Query: 439 DKFVQVEGGFACARDLVK 492
DKFVQ++GGFACA DLV+
Sbjct: 120 DKFVQIQGGFACALDLVQ 137
[7][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 229 bits (583), Expect = 9e-59
Identities = 113/138 (81%), Positives = 122/138 (88%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MKVIEKI EAA + + FSFE+FPPKTE+GV NL ERMDRMVAH PSF DITWGAGGS
Sbjct: 1 MKVIEKIQEAAGN--GRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGS 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
TAD+TL+IA +MQN V VETMMHLTCTNMPVEKID ALETIKSNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQ 118
Query: 439 DKFVQVEGGFACARDLVK 492
DKFVQVEGGFACA DLV+
Sbjct: 119 DKFVQVEGGFACALDLVQ 136
[8][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 227 bits (579), Expect = 3e-58
Identities = 113/138 (81%), Positives = 121/138 (87%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MKVIEKI EAA + FSFE+FPPKTE+GV NL ERMDRMVAH PSF DITWGAGGS
Sbjct: 1 MKVIEKILEAAGD--GRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGS 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
TAD+TL+IA +MQN V VETMMHLTCTNMPVEKID ALETIKSNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQ 118
Query: 439 DKFVQVEGGFACARDLVK 492
DKFVQVEGGFACA DLV+
Sbjct: 119 DKFVQVEGGFACALDLVQ 136
[9][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 227 bits (578), Expect = 4e-58
Identities = 112/138 (81%), Positives = 122/138 (88%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MKVIEKI EAAA + VFSFE+FPPKTE+G+ NL ERMDRMVAH P+F DITWGAGGS
Sbjct: 1 MKVIEKIQEAAAD--GRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGS 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
TAD+TL+IA +MQN V VETMMHLTCTNMPVEKIDDAL TIKSNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQ 118
Query: 439 DKFVQVEGGFACARDLVK 492
DKFVQV GGFACA DLV+
Sbjct: 119 DKFVQVAGGFACALDLVQ 136
[10][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 227 bits (578), Expect = 4e-58
Identities = 112/138 (81%), Positives = 122/138 (88%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MKVIEKI EAAA + VFSFE+FPPKTE+G+ NL ERMDRMVAH P+F DITWGAGGS
Sbjct: 1 MKVIEKIQEAAAD--GRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGS 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
TAD+TL+IA +MQN V VETMMHLTCTNMPVEKIDDAL TIKSNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQ 118
Query: 439 DKFVQVEGGFACARDLVK 492
DKFVQV GGFACA DLV+
Sbjct: 119 DKFVQVAGGFACALDLVQ 136
[11][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 226 bits (577), Expect = 5e-58
Identities = 116/151 (76%), Positives = 126/151 (83%), Gaps = 13/151 (8%)
Frame = +1
Query: 79 MKVIEKIHEA------------AASDPN-KVVFSFEFFPPKTEDGVVNLLERMDRMVAHS 219
MKVI+KI + A SD N KVVFSFEFFPPKTEDGV NL +RMDRMV+H+
Sbjct: 1 MKVIDKIKASVGASSHPHSNGGAISDSNDKVVFSFEFFPPKTEDGVDNLFDRMDRMVSHN 60
Query: 220 PSFXDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQ 399
P+F DITWGAGGSTAD+TLDIA KMQN + VETMMHLTCTNMPVEKID AL+TIKSNG+Q
Sbjct: 61 PTFCDITWGAGGSTADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALQTIKSNGIQ 120
Query: 400 NVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
NVLALRGDPPHGQDKFVQVEGGFACA DLVK
Sbjct: 121 NVLALRGDPPHGQDKFVQVEGGFACALDLVK 151
[12][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 224 bits (571), Expect = 2e-57
Identities = 111/138 (80%), Positives = 119/138 (86%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MKVIEKI A KVVFSFEFFPPKTE+GV NL +RMDRMV H PSF DITWGAGGS
Sbjct: 1 MKVIEKIQNAEKE--GKVVFSFEFFPPKTEEGVENLFDRMDRMVEHQPSFCDITWGAGGS 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
TAD+TLDI+ KMQN + VE+MMHLTCTNMPVEKID AL TIK+NG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLDISNKMQNMICVESMMHLTCTNMPVEKIDHALATIKANGIQNVLALRGDPPHGQ 118
Query: 439 DKFVQVEGGFACARDLVK 492
DKFVQVEGGFACA DLVK
Sbjct: 119 DKFVQVEGGFACALDLVK 136
[13][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 222 bits (565), Expect = 1e-56
Identities = 110/137 (80%), Positives = 118/137 (86%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MKVI+KI A D K FSFEFFPPKTEDGV NL ERMDRMVA+ P+F DITWGAGGS
Sbjct: 1 MKVIDKIQSLA--DEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGS 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
TAD+TLDIA +MQN V VE+MMHLTCTNMPVEKID ALETI+SNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQ 118
Query: 439 DKFVQVEGGFACARDLV 489
DKFVQVEGGF CA DLV
Sbjct: 119 DKFVQVEGGFDCALDLV 135
[14][TOP]
>UniRef100_Q3EAG8 Methylenetetrahydrofolate reductase n=1 Tax=Arabidopsis thaliana
RepID=Q3EAG8_ARATH
Length = 407
Score = 217 bits (553), Expect = 3e-55
Identities = 103/137 (75%), Positives = 120/137 (87%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MKV++KI + ++ + FSFEFFPPKTEDGV NL ERMDR+V++ P+F DITWGAGGS
Sbjct: 1 MKVVDKIK--SVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGS 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
TAD+TL+IA +MQN + VETMMHLTCTNMP+EKID ALETI+SNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIRSNGIQNVLALRGDPPHGQ 118
Query: 439 DKFVQVEGGFACARDLV 489
DKFVQVEGGFACA DLV
Sbjct: 119 DKFVQVEGGFACALDLV 135
[15][TOP]
>UniRef100_Q9SE60-2 Isoform 2 of Methylenetetrahydrofolate reductase 1 n=1
Tax=Arabidopsis thaliana RepID=Q9SE60-2
Length = 421
Score = 217 bits (553), Expect = 3e-55
Identities = 103/137 (75%), Positives = 120/137 (87%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MKV++KI + ++ + FSFEFFPPKTEDGV NL ERMDR+V++ P+F DITWGAGGS
Sbjct: 1 MKVVDKIK--SVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGS 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
TAD+TL+IA +MQN + VETMMHLTCTNMP+EKID ALETI+SNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIRSNGIQNVLALRGDPPHGQ 118
Query: 439 DKFVQVEGGFACARDLV 489
DKFVQVEGGFACA DLV
Sbjct: 119 DKFVQVEGGFACALDLV 135
[16][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 217 bits (553), Expect = 3e-55
Identities = 103/137 (75%), Positives = 120/137 (87%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MKV++KI + ++ + FSFEFFPPKTEDGV NL ERMDR+V++ P+F DITWGAGGS
Sbjct: 1 MKVVDKIK--SVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGS 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
TAD+TL+IA +MQN + VETMMHLTCTNMP+EKID ALETI+SNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIRSNGIQNVLALRGDPPHGQ 118
Query: 439 DKFVQVEGGFACARDLV 489
DKFVQVEGGFACA DLV
Sbjct: 119 DKFVQVEGGFACALDLV 135
[17][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 208 bits (530), Expect = 1e-52
Identities = 100/138 (72%), Positives = 116/138 (84%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MKVI+KI+ A VVFSFEFFPPKTE+GV NL +RMDRMV H P+F DITWGAGGS
Sbjct: 1 MKVIDKINNGLAG--GNVVFSFEFFPPKTEEGVENLFDRMDRMVMHQPAFCDITWGAGGS 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
T+ VTLDIA KMQN + VETMMHLTCTNM VE +D AL+++KSNG+QN+LALRGDPPHGQ
Sbjct: 59 TSAVTLDIANKMQNMICVETMMHLTCTNMLVETLDGALDSVKSNGIQNILALRGDPPHGQ 118
Query: 439 DKFVQVEGGFACARDLVK 492
DKFV +EGGF+CA DLV+
Sbjct: 119 DKFVTIEGGFSCALDLVR 136
[18][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 207 bits (527), Expect = 3e-52
Identities = 98/138 (71%), Positives = 116/138 (84%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MKVI+KI+ A VVFSFEFFPPKTE+GV NL +RMDRMV H P+F DITWGAGGS
Sbjct: 1 MKVIDKINNGLAG--GNVVFSFEFFPPKTEEGVENLFDRMDRMVRHQPAFCDITWGAGGS 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
T+ +TLDIA KMQN + VETMMHLTCTNM VE +D+AL+ +KSNG+QN+LALRGDPPHGQ
Sbjct: 59 TSAITLDIANKMQNMICVETMMHLTCTNMLVETLDNALDNVKSNGIQNILALRGDPPHGQ 118
Query: 439 DKFVQVEGGFACARDLVK 492
DKFV ++GGF+CA DLV+
Sbjct: 119 DKFVTIDGGFSCALDLVR 136
[19][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 193 bits (491), Expect = 4e-48
Identities = 92/112 (82%), Positives = 101/112 (90%)
Frame = +1
Query: 157 PKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTC 336
P+ +GV NL ERMDRMVAH P+F DITWGAGGSTADVTLDIA +MQN V VETMMHLTC
Sbjct: 13 PRRREGVENLFERMDRMVAHGPNFCDITWGAGGSTADVTLDIANRMQNMVCVETMMHLTC 72
Query: 337 TNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
TNMPVEKID+AL+TIKSNG+QNVLALRGDPPHGQDKFVQV GGF+CA DLV+
Sbjct: 73 TNMPVEKIDNALDTIKSNGIQNVLALRGDPPHGQDKFVQVAGGFSCALDLVE 124
[20][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 162 bits (411), Expect = 8e-39
Identities = 78/117 (66%), Positives = 92/117 (78%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MK+I K+ E + FSFEFFPP+TE+GV NL ER+DRMVA+ P F DITWGAGGS
Sbjct: 1 MKLIHKVEEKMKK--GETFFSFEFFPPRTEEGVENLFERLDRMVAYGPVFCDITWGAGGS 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 429
TADVTLDIA +MQN + VETMMHLTCTNMP EK++ AL +K G+QN+LALRGDPP
Sbjct: 59 TADVTLDIATRMQNLICVETMMHLTCTNMPEEKLESALHEVKKMGVQNILALRGDPP 115
[21][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 161 bits (407), Expect = 2e-38
Identities = 80/138 (57%), Positives = 105/138 (76%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MK+I+KI + S N +SFE+FPPKT +GV NL +R+ RM+ P F DITWGAGGS
Sbjct: 4 MKIIDKIQKKKES--NTPFYSFEYFPPKTMEGVQNLYDRLGRMLLFEPLFIDITWGAGGS 61
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
T+ +TL+IA+K QN G+ETMMHLTCTNMPV +I AL+ KS G++N+LALRGDPP G+
Sbjct: 62 TSALTLEIAEKAQNVCGLETMMHLTCTNMPVSEIIYALDKAKSTGIRNILALRGDPPRGE 121
Query: 439 DKFVQVEGGFACARDLVK 492
+ + ++EGGFA A DLV+
Sbjct: 122 E-WKKIEGGFAYAADLVR 138
[22][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 156 bits (394), Expect = 8e-37
Identities = 75/138 (54%), Positives = 101/138 (73%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MK+ +KI ++A +D K+ +SFE+FPP+T G+ NLL+R++RM A P F DITW AGG
Sbjct: 1 MKITQKIQQSANND--KIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGR 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
T+D+T ++ K Q +G+ET MHLTCTNMP EK+D AL K +G +NVLALRGDPP G+
Sbjct: 59 TSDLTSEMVKTCQGLIGMETCMHLTCTNMPKEKVDIALREAKQHGCRNVLALRGDPPSGK 118
Query: 439 DKFVQVEGGFACARDLVK 492
D++ VEGGF DLV+
Sbjct: 119 DEWEAVEGGFVHGIDLVR 136
[23][TOP]
>UniRef100_A9UZU5 Methylenetetrahydrofolate reductase n=1 Tax=Monosiga brevicollis
RepID=A9UZU5_MONBE
Length = 332
Score = 148 bits (373), Expect = 2e-34
Identities = 70/137 (51%), Positives = 96/137 (70%)
Frame = +1
Query: 82 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGST 261
K+ +++ E +A V SFEFFPP+T+DGV +L+ R+ R P F D+TWGAGGST
Sbjct: 5 KISDRLQELSAKGEKFV--SFEFFPPRTDDGVTSLMSRIQRYNDQQPLFMDMTWGAGGST 62
Query: 262 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 441
+D+TLD+ +M G MHLTCTNMP EKID AL+ + G++N++ALRGDPP G++
Sbjct: 63 SDLTLDLCTRMVKECGANANMHLTCTNMPSEKIDIALKGARDAGIRNIVALRGDPPAGEE 122
Query: 442 KFVQVEGGFACARDLVK 492
+ VEGG++CA DLVK
Sbjct: 123 AWEAVEGGYSCALDLVK 139
[24][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 147 bits (371), Expect = 4e-34
Identities = 73/138 (52%), Positives = 95/138 (68%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
M + EK+ + A++ +V SFEFFPPKT GV NL +RMDRM A PSF DITWGAGG
Sbjct: 1 MHIKEKLAQNEAAE--RVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGR 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL+ +G N+LALRGDPP +
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREK 118
Query: 439 DKFVQVEGGFACARDLVK 492
+K+ EGG A+DLVK
Sbjct: 119 EKWEAAEGGLRYAKDLVK 136
[25][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 145 bits (366), Expect = 1e-33
Identities = 72/138 (52%), Positives = 95/138 (68%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
M + EK+ + A+ + SFEFFPPKT GV NL +RMDRM A PSF DITWGAGG
Sbjct: 1 MHISEKLAQNEAA--GRPGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGR 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
+D+T ++ Q+ G+ET MHLTCT+MP+EK+D AL++ G N+LALRGDPP +
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVDAALQSAYKAGCTNILALRGDPPREK 118
Query: 439 DKFVQVEGGFACARDLVK 492
+K+ +GGF A+DLVK
Sbjct: 119 EKWEATDGGFRYAKDLVK 136
[26][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 144 bits (364), Expect = 2e-33
Identities = 72/138 (52%), Positives = 95/138 (68%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
M V +K+ E AA+ + SFE+FPPKT GV NL +RMDRM P+F D+TWGAGGS
Sbjct: 1 MHVGQKLQEQAAT--GRPGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGS 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
+++T ++ + Q G+ET MHLTCT+MP E++D ALE + G N+LALRGDPP Q
Sbjct: 59 RSELTCEMVRIAQTVFGLETCMHLTCTDMPRERVDAALEAAYNAGCTNILALRGDPPREQ 118
Query: 439 DKFVQVEGGFACARDLVK 492
+K+ EGGF A+DLVK
Sbjct: 119 EKWEAAEGGFRYAKDLVK 136
[27][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 144 bits (362), Expect = 4e-33
Identities = 71/138 (51%), Positives = 94/138 (68%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
M + +K+ A A+ + SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAHAEAT--GRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
+++T ++ Q+ G+ET MHLTCT+MP EK+D AL++ G N+LALRGDPP +
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDTALQSAFKAGCTNILALRGDPPREK 118
Query: 439 DKFVQVEGGFACARDLVK 492
+K+ EGGF A+DLVK
Sbjct: 119 EKWEATEGGFRYAKDLVK 136
[28][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 144 bits (362), Expect = 4e-33
Identities = 71/138 (51%), Positives = 94/138 (68%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
M + +K+ A A+ + SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAHAEAT--GRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
+++T ++ Q+ G+ET MHLTCT+MP EK+D AL++ G N+LALRGDPP +
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDTALQSAFKAGCTNILALRGDPPREK 118
Query: 439 DKFVQVEGGFACARDLVK 492
+K+ EGGF A+DLVK
Sbjct: 119 EKWEATEGGFRYAKDLVK 136
[29][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 144 bits (362), Expect = 4e-33
Identities = 70/138 (50%), Positives = 95/138 (68%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
M + +K+ A A+ + SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAHAEAT--GRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
+++T ++ Q+ G+ET MHLTCT+MP EK+D A+++ G N+LALRGDPP +
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAAIQSAFKAGCTNILALRGDPPREK 118
Query: 439 DKFVQVEGGFACARDLVK 492
+K+ +EGGF A+DLVK
Sbjct: 119 EKWEAIEGGFRYAKDLVK 136
[30][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 144 bits (362), Expect = 4e-33
Identities = 70/138 (50%), Positives = 95/138 (68%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
M + +K+ A A+ + SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAHAEAT--GRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
+++T ++ Q+ G+ET MHLTCT+MP EK+D A+++ G N+LALRGDPP +
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAAIQSAFKAGCTNILALRGDPPREK 118
Query: 439 DKFVQVEGGFACARDLVK 492
+K+ +EGGF A+DLVK
Sbjct: 119 EKWEAIEGGFRYAKDLVK 136
[31][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 143 bits (360), Expect = 7e-33
Identities = 70/129 (54%), Positives = 88/129 (68%)
Frame = +1
Query: 106 AAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIA 285
A A + SFEFFPPKT GV NL +RMDRM PSF DITWGAGG A++T ++
Sbjct: 8 ALAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLAELTCEMV 67
Query: 286 KKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 465
Q+ G+ET MHLTCT+MP EK+D+AL++ G N+LALRGDPP ++ + Q EGG
Sbjct: 68 HVAQSVYGLETCMHLTCTDMPREKVDEALQSAFKAGCTNILALRGDPPREKESWEQTEGG 127
Query: 466 FACARDLVK 492
F ARDLV+
Sbjct: 128 FRYARDLVQ 136
[32][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 143 bits (360), Expect = 7e-33
Identities = 73/140 (52%), Positives = 95/140 (67%), Gaps = 2/140 (1%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFXDITWGAGG 255
M++ EK+ S K FSFE+F PKT GV NL +RMDRM + P F D+TW AGG
Sbjct: 1 MRISEKLQNHR-SKSTKPTFSFEYFVPKTTQGVQNLYDRMDRMYQSTLPQFIDVTWNAGG 59
Query: 256 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 432
+ +T D+ + Q+ +G+ET MHLTCTNMPV +IDDALE+ + +G QN+LALRGDPP
Sbjct: 60 GVLSQLTTDLVETSQSVLGLETCMHLTCTNMPVSQIDDALESARLSGCQNILALRGDPPV 119
Query: 433 GQDKFVQVEGGFACARDLVK 492
D + VEGGF A+DLV+
Sbjct: 120 NSDSWQPVEGGFQYAKDLVR 139
[33][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 143 bits (360), Expect = 7e-33
Identities = 73/139 (52%), Positives = 93/139 (66%), Gaps = 1/139 (0%)
Frame = +1
Query: 79 MKVIEKI-HEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGG 255
M + +K+ H AA P+ SFEFFPPKT GV NL +RMDRM PSF DITWGAGG
Sbjct: 1 MHIKDKLAHSEAAGRPS---ISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFVDITWGAGG 57
Query: 256 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 435
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL++ G N+LALRGDPP
Sbjct: 58 RLSDLTAEMVNVSQSVYGLETCMHLTCTDMPREKVDWALQSAYKAGCTNILALRGDPPRE 117
Query: 436 QDKFVQVEGGFACARDLVK 492
++ + EGGF A+DLVK
Sbjct: 118 KEAWAPTEGGFQYAKDLVK 136
[34][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 143 bits (360), Expect = 7e-33
Identities = 72/138 (52%), Positives = 90/138 (65%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
M + EK+ + A K SFEFFPPKT GV NL +RMDRM PSF DITWGAGG
Sbjct: 1 MHIREKLAKNEAE--GKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGR 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
+D+T ++ Q+ G+ET MHLTCT+MPVEK+D AL+ G N+LALRGDPP +
Sbjct: 59 LSDLTCEMVSVAQSVYGLETCMHLTCTDMPVEKVDQALQAAYKAGCTNILALRGDPPREK 118
Query: 439 DKFVQVEGGFACARDLVK 492
+ + E GF A+DLVK
Sbjct: 119 EAWEAAENGFCYAKDLVK 136
[35][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 143 bits (360), Expect = 7e-33
Identities = 72/138 (52%), Positives = 92/138 (66%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
M V +K+++ A +V SFEFFPPKT GV NL +RMDRM A PSF DITWGAGG
Sbjct: 1 MHVKDKLYQNEAG--GQVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGR 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
+D+T ++ Q+ G+ET MHLTCT+MP+EK+D AL G N+LALRGDPP +
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVDAALSAAYKAGCTNILALRGDPPRDK 118
Query: 439 DKFVQVEGGFACARDLVK 492
+ + EGG A+DLVK
Sbjct: 119 EAWEATEGGLRYAKDLVK 136
[36][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 142 bits (359), Expect = 9e-33
Identities = 69/119 (57%), Positives = 83/119 (69%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVE 315
FSFE+FPPKT GV NL +RMDRM P F DITWGAGG A++T ++ + Q G+E
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIAELTCEMVLQAQAVYGLE 77
Query: 316 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
T MHLTCT+M VEK++DAL G N+LALRGDPP QDK+ +GGF ARDLVK
Sbjct: 78 TCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRDQDKWTAADGGFQYARDLVK 136
[37][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 142 bits (359), Expect = 9e-33
Identities = 67/118 (56%), Positives = 85/118 (72%)
Frame = +1
Query: 139 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVET 318
SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +++T ++ Q+ G+ET
Sbjct: 19 SFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLSELTCEMVNVAQSVYGLET 78
Query: 319 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
MHLTCT+MP EK+D AL++ G N+LALRGDPP ++K+ EGGF A+DLVK
Sbjct: 79 CMHLTCTDMPSEKVDAALQSAFKAGCTNILALRGDPPREKEKWEATEGGFRYAKDLVK 136
[38][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 142 bits (359), Expect = 9e-33
Identities = 67/118 (56%), Positives = 85/118 (72%)
Frame = +1
Query: 139 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVET 318
SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +++T ++ Q+ G+ET
Sbjct: 19 SFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLSELTCEMVNVAQSVYGLET 78
Query: 319 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
MHLTCT+MP EK+D AL++ G N+LALRGDPP ++K+ EGGF A+DLVK
Sbjct: 79 CMHLTCTDMPSEKVDAALQSAFKAGCTNILALRGDPPREKEKWEATEGGFRYAKDLVK 136
[39][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 142 bits (358), Expect = 1e-32
Identities = 69/119 (57%), Positives = 83/119 (69%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVE 315
FSFE+FPPKT GV NL +RMDRM P F DITWGAGG A++T ++ + Q G+E
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIAELTCEMVLQAQAVYGLE 77
Query: 316 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
T MHLTCT+M VEK++DAL G N+LALRGDPP QDK+ +GGF ARDLVK
Sbjct: 78 TCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDKWEAADGGFQYARDLVK 136
[40][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 142 bits (358), Expect = 1e-32
Identities = 73/139 (52%), Positives = 92/139 (66%), Gaps = 1/139 (0%)
Frame = +1
Query: 79 MKVIEKI-HEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGG 255
M V EK+ H A+ P+ SFEFFPPKT GV NL +RMDRM P+F DITWGAGG
Sbjct: 1 MHVKEKLAHSEASGRPS---ISFEFFPPKTAQGVQNLYDRMDRMHGLGPAFIDITWGAGG 57
Query: 256 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 435
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL+ G N+LALRGDPP
Sbjct: 58 RLSDLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDWALQCAHKAGCTNILALRGDPPRE 117
Query: 436 QDKFVQVEGGFACARDLVK 492
++ + EGGF A+DLVK
Sbjct: 118 KESWAPTEGGFRYAKDLVK 136
[41][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 142 bits (358), Expect = 1e-32
Identities = 73/139 (52%), Positives = 92/139 (66%), Gaps = 1/139 (0%)
Frame = +1
Query: 79 MKVIEKI-HEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGG 255
M V EK+ H A+ P+ SFEFFPPKT GV NL +RMDRM P+F DITWGAGG
Sbjct: 1 MHVKEKLAHSEASGRPS---ISFEFFPPKTAQGVQNLYDRMDRMHGLGPAFIDITWGAGG 57
Query: 256 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 435
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL+ G N+LALRGDPP
Sbjct: 58 RLSDLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDWALQCAHKAGCTNILALRGDPPRE 117
Query: 436 QDKFVQVEGGFACARDLVK 492
++ + EGGF A+DLVK
Sbjct: 118 KESWAPTEGGFRYAKDLVK 136
[42][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 142 bits (358), Expect = 1e-32
Identities = 67/118 (56%), Positives = 85/118 (72%)
Frame = +1
Query: 139 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVET 318
SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +++T ++ Q+ G+ET
Sbjct: 19 SFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLSELTCEMVNVAQSVYGLET 78
Query: 319 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
MHLTCT+MP EK+D AL++ G N+LALRGDPP ++K+ EGGF A+DLVK
Sbjct: 79 CMHLTCTDMPREKVDAALQSAFKAGCTNILALRGDPPREKEKWEATEGGFRYAKDLVK 136
[43][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 142 bits (358), Expect = 1e-32
Identities = 70/138 (50%), Positives = 94/138 (68%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
M + +K+ E S + SFE+FPPKT GV NL +RMDRM P+F D+TWGAGGS
Sbjct: 1 MHIGQKLQEQETS--GRPGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGS 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
+++T ++ + Q G+ET MHLTCT+MP E++D ALE+ + G N+LALRGDPP Q
Sbjct: 59 RSELTCEMVRIAQTVFGLETCMHLTCTDMPRERVDAALESAYNAGCTNILALRGDPPREQ 118
Query: 439 DKFVQVEGGFACARDLVK 492
+K+ EGGF A+DLVK
Sbjct: 119 EKWEAAEGGFRYAKDLVK 136
[44][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 142 bits (358), Expect = 1e-32
Identities = 71/138 (51%), Positives = 92/138 (66%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
M + EK+ + A+ + SFEFFPPKT GV NL +RMDRM A PSF DITWGAGG
Sbjct: 1 MHIKEKLAQNEAA--GRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGR 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL+ G N+LALRGDPP +
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYKAGCTNILALRGDPPRDK 118
Query: 439 DKFVQVEGGFACARDLVK 492
+ + +GGF A+DLVK
Sbjct: 119 EAWEAADGGFRYAKDLVK 136
[45][TOP]
>UniRef100_C9S7I4 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S7I4_9PEZI
Length = 181
Score = 142 bits (357), Expect = 2e-32
Identities = 67/119 (56%), Positives = 85/119 (71%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVE 315
FSFE+FPPKT GV NL +RMDRM P F DITWGAGG A++T ++ + Q+ G+E
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIAELTCEMVTQAQSVYGLE 77
Query: 316 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
T MHLTCT+M +EK++DAL G N+LALRGDPP ++K+V +GGF ARDLVK
Sbjct: 78 TCMHLTCTDMGLEKVNDALRKGYKAGCTNILALRGDPPREKEKWVAADGGFEYARDLVK 136
[46][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 141 bits (355), Expect = 3e-32
Identities = 70/138 (50%), Positives = 92/138 (66%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
M + EK+ + A+ K+ SFEFFPPKT GV NL +RMDRM PSF DITWGAGG
Sbjct: 1 MHIKEKLAQNEAA--GKIGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGR 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
+D+T ++ Q+ G+ET MHLTCT+MP E++D AL+ G N+LALRGDPP +
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPQERVDAALQAAYKAGCTNILALRGDPPREK 118
Query: 439 DKFVQVEGGFACARDLVK 492
+ + +GGF A+DLVK
Sbjct: 119 EVWEAADGGFRYAKDLVK 136
[47][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 140 bits (352), Expect = 6e-32
Identities = 69/138 (50%), Positives = 93/138 (67%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MK+ K+ +A A+D FSFEFF PKT GV NL +RMDRM P F DITW AGG
Sbjct: 1 MKISHKLEKAHAADSTPT-FSFEFFVPKTSQGVNNLYDRMDRMYQLGPQFIDITWNAGGR 59
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
+++T ++ Q+ +G+ET MHLTCT MP + +++AL++ G QN+LALRGDPP
Sbjct: 60 LSNLTNEMVATAQSALGLETCMHLTCTGMPKQLVENALQSAFDGGCQNILALRGDPPVES 119
Query: 439 DKFVQVEGGFACARDLVK 492
+K+ V+GGF A+DLVK
Sbjct: 120 EKWEAVDGGFRYAKDLVK 137
[48][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 139 bits (350), Expect = 1e-31
Identities = 69/138 (50%), Positives = 89/138 (64%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
M + +K+ +A A K FSFEFFPPKT GV NL +RMDRM P F D+TWGAGG
Sbjct: 1 MHISQKLAQAKAE--GKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGR 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
+ +T ++ K Q G+ET MHLTCT+M K+D+AL +G N+LALRGDPP +
Sbjct: 59 HSKLTCEMVKVAQTVYGLETCMHLTCTDMEKTKLDEALRDAYQSGCTNILALRGDPPRER 118
Query: 439 DKFVQVEGGFACARDLVK 492
+K+ GGF A+DLVK
Sbjct: 119 EKWEATAGGFRYAKDLVK 136
[49][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 139 bits (350), Expect = 1e-31
Identities = 71/140 (50%), Positives = 92/140 (65%), Gaps = 2/140 (1%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFXDITWGAGG 255
MK+ EK+ + + K +SFE+F PKT GV NL +RMDRM S P F DITW AGG
Sbjct: 1 MKITEKLEQHRQTS-GKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGG 59
Query: 256 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 432
+ ++ D+ Q+ +G+ET MHLTCTNMP+ IDDALE +G QN+LALRGDPP
Sbjct: 60 GRLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPR 119
Query: 433 GQDKFVQVEGGFACARDLVK 492
+ + VEGGF A+DL+K
Sbjct: 120 DAENWTPVEGGFQYAKDLIK 139
[50][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 139 bits (350), Expect = 1e-31
Identities = 71/140 (50%), Positives = 92/140 (65%), Gaps = 2/140 (1%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFXDITWGAGG 255
MK+ EK+ + + K +SFE+F PKT GV NL +RMDRM S P F DITW AGG
Sbjct: 1 MKITEKLEQHRQTS-GKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGG 59
Query: 256 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 432
+ ++ D+ Q+ +G+ET MHLTCTNMP+ IDDALE +G QN+LALRGDPP
Sbjct: 60 GRLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPR 119
Query: 433 GQDKFVQVEGGFACARDLVK 492
+ + VEGGF A+DL+K
Sbjct: 120 DAENWTPVEGGFQYAKDLIK 139
[51][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 139 bits (350), Expect = 1e-31
Identities = 71/140 (50%), Positives = 92/140 (65%), Gaps = 2/140 (1%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFXDITWGAGG 255
MK+ EK+ + + K +SFE+F PKT GV NL +RMDRM S P F DITW AGG
Sbjct: 1 MKITEKLEQHRQTS-GKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGG 59
Query: 256 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 432
+ ++ D+ Q+ +G+ET MHLTCTNMP+ IDDALE +G QN+LALRGDPP
Sbjct: 60 GRLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPR 119
Query: 433 GQDKFVQVEGGFACARDLVK 492
+ + VEGGF A+DL+K
Sbjct: 120 DAENWTPVEGGFQYAKDLIK 139
[52][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 138 bits (348), Expect = 2e-31
Identities = 70/141 (49%), Positives = 96/141 (68%), Gaps = 3/141 (2%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFXDITWGAGG 255
MK+ +K+ + P+K FSFE+F PKT GV NL +RMDRM S P F DITW AGG
Sbjct: 1 MKITQKLADRHKEKPDKATFSFEYFVPKTTQGVQNLYDRMDRMYEASLPEFIDITWNAGG 60
Query: 256 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP- 429
+ ++ ++ Q+ +G+ET MHLTCTNMP+ +ID+ALE ++G QN+LALRGDPP
Sbjct: 61 GRLSQLSTELVATAQSVLGLETCMHLTCTNMPISQIDEALEDAYNSGCQNILALRGDPPL 120
Query: 430 HGQDKFVQVEGGFACARDLVK 492
+ + + +EGGF A+DLVK
Sbjct: 121 NAPNGWQPIEGGFNYAKDLVK 141
[53][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 138 bits (348), Expect = 2e-31
Identities = 69/139 (49%), Positives = 91/139 (65%), Gaps = 1/139 (0%)
Frame = +1
Query: 79 MKVIEKIHE-AAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGG 255
M+V EK+ + A+ +K FSFEFF PKT GV NL +RMDRM P F DITW AGG
Sbjct: 1 MRVSEKLQKNREANGTSKATFSFEFFVPKTSQGVQNLYDRMDRMYQTHPQFIDITWNAGG 60
Query: 256 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 435
+ ++ ++ Q+ +G+ET MHLTCTNMP + IDDAL+ +G QN+LALRGD P
Sbjct: 61 RLSQLSTELVSTSQSVLGLETCMHLTCTNMPRQLIDDALQKAYESGCQNILALRGDAPIT 120
Query: 436 QDKFVQVEGGFACARDLVK 492
++ EGGF A+DLV+
Sbjct: 121 SSEWKPCEGGFTYAKDLVR 139
[54][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 138 bits (347), Expect = 2e-31
Identities = 66/122 (54%), Positives = 84/122 (68%)
Frame = +1
Query: 127 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTV 306
+V SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +D+T ++ Q+
Sbjct: 15 RVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLSDLTCEMVNVAQSVY 74
Query: 307 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDL 486
G+ET MHLTCT+MP+EK++ AL G N+LALRGDPP ++ + EGG A+DL
Sbjct: 75 GLETCMHLTCTDMPLEKVNAALSAAYKAGCTNILALRGDPPRDKEAWEATEGGLRYAKDL 134
Query: 487 VK 492
VK
Sbjct: 135 VK 136
[55][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 138 bits (347), Expect = 2e-31
Identities = 67/137 (48%), Positives = 91/137 (66%)
Frame = +1
Query: 82 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGST 261
K+ KI A A ++ +SFE+FPP+T G+ NL +R++RM P F DITW AGG T
Sbjct: 18 KITNKI--AKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERMADLGPEFVDITWNAGGRT 75
Query: 262 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 441
+D+T + K + +G+ET MHLTCTNMP EKID AL+ K G +N+LALRGDPP GQ
Sbjct: 76 SDLTASLVKTVHTYIGLETCMHLTCTNMPREKIDTALKEAKEFGCRNILALRGDPPAGQS 135
Query: 442 KFVQVEGGFACARDLVK 492
++ GF A++LV+
Sbjct: 136 EWEPHAAGFTRAKELVE 152
[56][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 138 bits (347), Expect = 2e-31
Identities = 66/122 (54%), Positives = 84/122 (68%)
Frame = +1
Query: 127 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTV 306
+V SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +D+T ++ Q+
Sbjct: 15 RVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLSDLTCEMVNVAQSVY 74
Query: 307 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDL 486
G+ET MHLTCT+MP+EK++ AL G N+LALRGDPP ++ + EGG A+DL
Sbjct: 75 GLETCMHLTCTDMPLEKVNAALSAAYKAGCTNILALRGDPPRDKEAWEATEGGLRYAKDL 134
Query: 487 VK 492
VK
Sbjct: 135 VK 136
[57][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 138 bits (347), Expect = 2e-31
Identities = 66/122 (54%), Positives = 84/122 (68%)
Frame = +1
Query: 127 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTV 306
+V SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +D+T ++ Q+
Sbjct: 15 RVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLSDLTCEMVNVAQSVY 74
Query: 307 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDL 486
G+ET MHLTCT+MP+EK++ AL G N+LALRGDPP ++ + EGG A+DL
Sbjct: 75 GLETCMHLTCTDMPLEKVNAALSAAYKAGCTNILALRGDPPRDKEAWEATEGGLRYAKDL 134
Query: 487 VK 492
VK
Sbjct: 135 VK 136
[58][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 137 bits (346), Expect = 3e-31
Identities = 66/126 (52%), Positives = 82/126 (65%)
Frame = +1
Query: 112 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKK 291
A + K FSFEFFPPKT GV NL +RMDRM P F D+TWGAGG + +T ++ K
Sbjct: 10 AREEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHSKLTCEMVKV 69
Query: 292 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFA 471
Q G+ET MHLTCT+M K+DDAL +G N+LALRGDPP ++K+ GGF
Sbjct: 70 AQTVYGLETCMHLTCTDMEKSKLDDALREAYQSGCTNILALRGDPPREREKWEATAGGFR 129
Query: 472 CARDLV 489
A+DLV
Sbjct: 130 YAKDLV 135
[59][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 137 bits (346), Expect = 3e-31
Identities = 67/118 (56%), Positives = 81/118 (68%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVE 315
FSFEFFPPKT GV NL +RMDRM PSF DITWGAGG A +T ++ Q+ G+E
Sbjct: 18 FSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLAQLTCEMVGVAQSQYGLE 77
Query: 316 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLV 489
T MHLTCT+M EK+D+AL G N+LALRGDPP ++K+ EGGF A+DLV
Sbjct: 78 TCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEKWEATEGGFQYAKDLV 135
[60][TOP]
>UniRef100_A6SLU6 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6SLU6_BOTFB
Length = 390
Score = 137 bits (346), Expect = 3e-31
Identities = 67/118 (56%), Positives = 81/118 (68%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVE 315
FSFEFFPPKT GV NL +RMDRM PSF DITWGAGG A +T ++ Q+ G+E
Sbjct: 18 FSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLAQLTCEMVGVAQSQYGLE 77
Query: 316 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLV 489
T MHLTCT+M EK+D+AL G N+LALRGDPP ++K+ EGGF A+DLV
Sbjct: 78 TCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEKWEATEGGFQYAKDLV 135
[61][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 136 bits (342), Expect = 8e-31
Identities = 65/118 (55%), Positives = 81/118 (68%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVE 315
FSFE+FPPKT GV NL +RM+RM P F DITWGAGG A++T ++ + Q +G+E
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMERMYNFGPKFVDITWGAGGRIAELTCEMVVQAQTYLGLE 77
Query: 316 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLV 489
MHLTCT+M EK++DAL G N+LALRGDPP Q+K+ EGGF ARDLV
Sbjct: 78 ACMHLTCTDMGEEKVNDALRKAYKAGCTNILALRGDPPREQEKWEATEGGFQYARDLV 135
[62][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 136 bits (342), Expect = 8e-31
Identities = 65/119 (54%), Positives = 83/119 (69%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVE 315
FSFE+FPPKT GV NL +RM+RM P F DITWGAGG A++T ++ + Q +G+E
Sbjct: 18 FSFEYFPPKTTQGVQNLYDRMERMNNFGPKFIDITWGAGGRIAELTCEMVVQAQTYLGLE 77
Query: 316 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
T MHLTCT+M EK++DAL G N+LALRGDPP ++K+ EGGF ARDLV+
Sbjct: 78 TCMHLTCTDMGEEKVNDALRKAYKAGCTNILALRGDPPREKEKWEAAEGGFRYARDLVQ 136
[63][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 135 bits (340), Expect = 1e-30
Identities = 64/118 (54%), Positives = 83/118 (70%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVE 315
FSFE+FPPKT GV NL +RMDRM P F DITWGAGG A++T ++ + Q +G+E
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIAELTCEMVAQAQAYLGLE 77
Query: 316 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLV 489
T MHLTCT+M EK+++AL+ G N+LALRGDPP ++++ EGGF ARDLV
Sbjct: 78 TCMHLTCTDMGEEKVNNALQRAYKAGCTNILALRGDPPREKERWEAAEGGFQYARDLV 135
[64][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 135 bits (340), Expect = 1e-30
Identities = 72/139 (51%), Positives = 92/139 (66%), Gaps = 1/139 (0%)
Frame = +1
Query: 79 MKVIEKIHEA-AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGG 255
MK+ EK+ +A S+P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MKISEKLTQAHKGSNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 256 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 435
++ +T ++ Q+T+G+ET MHLTCTNM VE ID+ALE +G QN+LALRGDPP
Sbjct: 61 RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALEKAFKSGCQNILALRGDPPLD 120
Query: 436 QDKFVQVEGGFACARDLVK 492
+ G F A+DL+K
Sbjct: 121 GS---ESTGDFKYAKDLIK 136
[65][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 135 bits (340), Expect = 1e-30
Identities = 72/139 (51%), Positives = 91/139 (65%), Gaps = 1/139 (0%)
Frame = +1
Query: 79 MKVIEKIHEA-AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGG 255
MK+ EK+ +A S P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MKISEKLSQAHRGSKPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 256 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 435
++ +T ++ Q+T+G+ET MHLTCTNM VE ID+ALE +G QN+LALRGDPP
Sbjct: 61 RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALEKAYKSGCQNILALRGDPPLD 120
Query: 436 QDKFVQVEGGFACARDLVK 492
+ G F A+DL+K
Sbjct: 121 GS---ESTGDFKYAKDLIK 136
[66][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 135 bits (339), Expect = 2e-30
Identities = 68/138 (49%), Positives = 89/138 (64%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MK+ EK+ +A + +SFEFFPP+T G+ NL +R++RM P F DITWGAGG
Sbjct: 1 MKITEKLQKAEKE--GRPFWSFEFFPPRTAQGLQNLYDRIERMRDLGPEFIDITWGAGGK 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
AD+T + + Q T+G+ET MHL CT MP EK++ AL KS+G QN+LALRGDP G
Sbjct: 59 NADLTNSLVQVCQATIGIETCMHLCCTEMPKEKVEWALREAKSHGCQNILALRGDPVAGT 118
Query: 439 DKFVQVEGGFACARDLVK 492
+ GGF A DLV+
Sbjct: 119 STWEPTPGGFMNAVDLVR 136
[67][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 134 bits (337), Expect = 3e-30
Identities = 65/128 (50%), Positives = 83/128 (64%)
Frame = +1
Query: 106 AAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIA 285
A K FSFE+FPPKT GV NL +RM+RM P F DITWGAGG A++T ++
Sbjct: 3 AETEKTGKPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIAELTCEMV 62
Query: 286 KKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 465
+ Q G+ET MHLTCT+M VEK++DAL G N+LALRGDPP ++K+ + G
Sbjct: 63 TQAQTYFGLETCMHLTCTDMGVEKVNDALSKAYKAGCTNILALRGDPPRDKEKWEAAQDG 122
Query: 466 FACARDLV 489
F A+DLV
Sbjct: 123 FNYAKDLV 130
[68][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 134 bits (336), Expect = 4e-30
Identities = 69/139 (49%), Positives = 91/139 (65%), Gaps = 2/139 (1%)
Frame = +1
Query: 79 MKVIEKIHEA--AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAG 252
MK+ EK+H+A ++ P FSFEFF PKT GV NL +RMDRM +P F DITW AG
Sbjct: 1 MKISEKLHQAHSGSTRPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAG 60
Query: 253 GSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 432
G ++ +T ++ Q+T+G+ET MHLTCTNM +E ID+AL +G QN+LALRGDPP
Sbjct: 61 GRSSSLTNEMVYTAQSTLGLETCMHLTCTNMKIELIDEALSKAYKSGCQNILALRGDPPL 120
Query: 433 GQDKFVQVEGGFACARDLV 489
+ G F A+DL+
Sbjct: 121 DGS---ESTGDFKYAKDLI 136
[69][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 133 bits (334), Expect = 7e-30
Identities = 68/138 (49%), Positives = 89/138 (64%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MK+ EK+ A + FSFEFF PKT GV NL +RMDRM SP F DITW AGG
Sbjct: 1 MKITEKLSSAHRREDAPPTFSFEFFTPKTAQGVQNLYDRMDRMYNLSPQFIDITWNAGGR 60
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
++++T ++ Q +G+ET MHLTCTNM +E ID+AL++ +G QN+LALRGDPP
Sbjct: 61 SSNLTCEMINTAQTVLGLETCMHLTCTNMTLEVIDEALKSAYDSGCQNILALRGDPPLDG 120
Query: 439 DKFVQVEGGFACARDLVK 492
+ G F A+DL+K
Sbjct: 121 S---ESTGCFRYAKDLIK 135
[70][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 132 bits (332), Expect = 1e-29
Identities = 68/141 (48%), Positives = 89/141 (63%), Gaps = 4/141 (2%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
M++ +K+ + A + FSFEFF PKT GV NL ERMDRM P F DITW AGG
Sbjct: 1 MRISQKL-QRAHEEREDATFSFEFFVPKTSQGVQNLYERMDRMYQTQPEFIDITWNAGGR 59
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG- 435
+ ++ D+ Q +G+ET MHLTCTNMPV +IDDAL+ G +N+LALRGDPP
Sbjct: 60 LSMLSTDLVATSQGVLGLETCMHLTCTNMPVSQIDDALKKAYDAGCENILALRGDPPINS 119
Query: 436 ---QDKFVQVEGGFACARDLV 489
++++ E GF A+DLV
Sbjct: 120 LGEEEEWKPCENGFRYAKDLV 140
[71][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 132 bits (331), Expect = 2e-29
Identities = 72/140 (51%), Positives = 92/140 (65%), Gaps = 3/140 (2%)
Frame = +1
Query: 79 MKVIEKI---HEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGA 249
MK+ EK+ H+AA S P FSFEFF PKT GV NL +RMDRM +P F DITW A
Sbjct: 1 MKISEKLDQAHKAAHSPP--ATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNA 58
Query: 250 GGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 429
GG ++ +T ++ Q+T+G+ET MHLTCTNM VE ID+AL+ +G QN+LALRGDPP
Sbjct: 59 GGRSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALDKAYKSGCQNILALRGDPP 118
Query: 430 HGQDKFVQVEGGFACARDLV 489
+ G F A+DL+
Sbjct: 119 LDGS---ESTGDFKYAKDLI 135
[72][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 131 bits (330), Expect = 2e-29
Identities = 68/139 (48%), Positives = 91/139 (65%), Gaps = 1/139 (0%)
Frame = +1
Query: 79 MKVIEKIHEA-AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGG 255
M++ EK+ +A + S P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MRISEKLSQAHSTSSPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 256 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 435
++ +T ++ Q+T+G+ET MHLTCTNM +E ID+AL +G QN+LALRGDPP
Sbjct: 61 RSSSLTNEMVYTAQSTLGLETCMHLTCTNMKIELIDEALHKAYVSGCQNILALRGDPPLD 120
Query: 436 QDKFVQVEGGFACARDLVK 492
+ G F A+DL++
Sbjct: 121 GS---ESTGDFKYAKDLIR 136
[73][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 131 bits (330), Expect = 2e-29
Identities = 69/139 (49%), Positives = 92/139 (66%), Gaps = 1/139 (0%)
Frame = +1
Query: 79 MKVIEKIHEAAAS-DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGG 255
MK+ +K+ +A +S +P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MKISDKLSQAHSSANPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 256 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 435
++ +T ++ Q+T+G+ET MHLTCTNM VE ID+AL +G QN+LALRGDPP
Sbjct: 61 RSSSLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALHKAFESGCQNILALRGDPPLD 120
Query: 436 QDKFVQVEGGFACARDLVK 492
+ G F A+DL++
Sbjct: 121 GS---ESTGDFKYAKDLIE 136
[74][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 130 bits (328), Expect = 4e-29
Identities = 68/139 (48%), Positives = 91/139 (65%), Gaps = 1/139 (0%)
Frame = +1
Query: 79 MKVIEKIHEA-AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGG 255
M++ EK+ +A + S P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MRISEKLLQAHSTSSPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 256 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 435
++ +T ++ Q+T+G+ET MHLTCTNM +E ID+AL +G QN+LALRGDPP
Sbjct: 61 RSSSLTNEMVYTAQSTLGLETCMHLTCTNMKIELIDEALHKAYVSGCQNILALRGDPPLD 120
Query: 436 QDKFVQVEGGFACARDLVK 492
+ G F A+DL++
Sbjct: 121 GS---ESTGDFKYAKDLIR 136
[75][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 130 bits (327), Expect = 5e-29
Identities = 67/139 (48%), Positives = 94/139 (67%), Gaps = 1/139 (0%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFXDITWGAGG 255
MK+ +K+ D +V +S+E+FPPKT GVVNL R++RM P+F D+TWGAGG
Sbjct: 1 MKITDKLQLPEYRD--RVTWSYEYFPPKTSTGVVNLYNRIERMRDWGHPTFVDVTWGAGG 58
Query: 256 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 435
S++D+T I K Q+ G++T MHLTCTNM ++ID+ALE G +N+LALRGDP
Sbjct: 59 SSSDLTPVIVKVTQSDYGLDTCMHLTCTNMATKQIDEALERAYKVGCRNILALRGDPVKH 118
Query: 436 QDKFVQVEGGFACARDLVK 492
+ ++ +EGGF A DLV+
Sbjct: 119 ESEWTALEGGFEYACDLVR 137
[76][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 130 bits (326), Expect = 6e-29
Identities = 60/137 (43%), Positives = 93/137 (67%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MK+ +KI AA DP++ ++FEFFPP+T+ G NL+ R+ R+ +P +TWGAGGS
Sbjct: 1 MKLSDKI---AAHDPSQPFYTFEFFPPRTDQGFENLVSRISRLATLNPLAISVTWGAGGS 57
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
T D +L++A Q ++T++HLTCTNM +D+ L+ ++ G+QN+LALRGDPP G+
Sbjct: 58 TKDRSLELASLTQGDYHLDTLLHLTCTNMEQGLVDEVLKAVRDRGIQNILALRGDPPRGE 117
Query: 439 DKFVQVEGGFACARDLV 489
++++ + F A DLV
Sbjct: 118 EEWIPSDPRFTHAVDLV 134
[77][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NEV2_COPC7
Length = 617
Score = 129 bits (324), Expect = 1e-28
Identities = 63/138 (45%), Positives = 92/138 (66%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MK+ +KI E DP+K ++FEFFPP+T+ G NL+ R+ R+ P ITWGAGGS
Sbjct: 1 MKLSQKIAE---HDPSKPFYTFEFFPPRTDQGTENLIARISRLSTLDPLAISITWGAGGS 57
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
T + +LD+A Q+ ++T++HLTCTNM IDD L+ +K G++ +LALRGDPP G+
Sbjct: 58 TKERSLDLASITQSQHRLDTILHLTCTNMEQGLIDDVLKDVKDRGIETILALRGDPPRGE 117
Query: 439 DKFVQVEGGFACARDLVK 492
++++ + F A DLVK
Sbjct: 118 EEWIPSDPRFTHAIDLVK 135
[78][TOP]
>UniRef100_A3LW82 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LW82_PICST
Length = 635
Score = 128 bits (322), Expect = 2e-28
Identities = 64/128 (50%), Positives = 89/128 (69%)
Frame = +1
Query: 109 AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAK 288
AA P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 9 AALGPDEKFISFEFFPPKTDSGFRNLLARLNRMSALNPLFITVTWGAGGSTSEKSLDLAA 68
Query: 289 KMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGF 468
QN +G+ T++HLTCTN E ID+AL+ K +G++N+LALRGDPP ++ + F
Sbjct: 69 TCQNDLGLTTILHLTCTNTNKEIIDEALKRAKESGIRNILALRGDPPRAEEYWTP-NCDF 127
Query: 469 ACARDLVK 492
A DLV+
Sbjct: 128 NSAVDLVR 135
[79][TOP]
>UniRef100_B9WCV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WCV3_CANDC
Length = 640
Score = 128 bits (321), Expect = 2e-28
Identities = 64/128 (50%), Positives = 88/128 (68%)
Frame = +1
Query: 109 AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAK 288
A+ P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 9 ASLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFITVTWGAGGSTSEKSLDLAA 68
Query: 289 KMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGF 468
QN +G+ T++HLTCTN E ID AL K+ G++N+LALRGDPP ++ + F
Sbjct: 69 TCQNEIGITTVLHLTCTNTNKEVIDQALSKAKAAGVRNILALRGDPPRTEEYWTP-NCDF 127
Query: 469 ACARDLVK 492
+ A DLVK
Sbjct: 128 SGAVDLVK 135
[80][TOP]
>UniRef100_UPI00003BE162 hypothetical protein DEHA0F09867g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE162
Length = 642
Score = 127 bits (320), Expect = 3e-28
Identities = 64/127 (50%), Positives = 89/127 (70%)
Frame = +1
Query: 112 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKK 291
A P++ SFEFFPPKT+ G NLL R++RM+A +P F +TWGAGGST++ +LD+A
Sbjct: 10 ALKPHERFVSFEFFPPKTDTGFRNLLARLNRMLALNPLFITVTWGAGGSTSEKSLDLAAT 69
Query: 292 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFA 471
Q +G+ T++HLTCTN E ID+ALE K G++N+LALRGDPP ++ ++ + F
Sbjct: 70 CQKEIGLTTVLHLTCTNTNKEIIDNALEKAKEQGIRNILALRGDPPRTEEYWIP-DCDFN 128
Query: 472 CARDLVK 492
A DLVK
Sbjct: 129 NAVDLVK 135
[81][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 127 bits (320), Expect = 3e-28
Identities = 67/141 (47%), Positives = 88/141 (62%), Gaps = 4/141 (2%)
Frame = +1
Query: 79 MKVIEKIHEA----AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWG 246
MK+ +K+ +A FSFEFF PKT G+ NL +RMDRM +P F DITW
Sbjct: 1 MKITDKLQQAHSCKVGGSAPPATFSFEFFVPKTSQGLQNLYDRMDRMYDLNPIFIDITWN 60
Query: 247 AGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 426
AGG ++ +T ++ Q+T+G+ET MHLTCTNMPV ID+ALE +G QN+LALRGDP
Sbjct: 61 AGGRSSTLTNEMVYTAQSTLGLETCMHLTCTNMPVSLIDEALEKAFKSGCQNILALRGDP 120
Query: 427 PHGQDKFVQVEGGFACARDLV 489
P + G F A+DL+
Sbjct: 121 PLDGS---ESTGDFKYAKDLI 138
[82][TOP]
>UniRef100_UPI000151A866 hypothetical protein PGUG_01501 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151A866
Length = 642
Score = 127 bits (319), Expect = 4e-28
Identities = 66/138 (47%), Positives = 92/138 (66%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
M V++KI+ D SFEFFPPKT+ G NLL R+ RM+A +P F +TWGAGGS
Sbjct: 1 MSVVQKINSLGPQDR---FISFEFFPPKTDTGFRNLLARLHRMLALNPLFITVTWGAGGS 57
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
T++ +LD+A Q +G+ T++HLTCTN + ID+AL+ K NG++N+LALRGDPP +
Sbjct: 58 TSEKSLDLAITCQKELGLTTVLHLTCTNTNKDIIDNALQRAKENGIRNILALRGDPPRTE 117
Query: 439 DKFVQVEGGFACARDLVK 492
+ + + F A DLVK
Sbjct: 118 EYWTP-DCDFYSAVDLVK 134
[83][TOP]
>UniRef100_C5M548 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M548_CANTT
Length = 633
Score = 127 bits (319), Expect = 4e-28
Identities = 59/107 (55%), Positives = 79/107 (73%)
Frame = +1
Query: 121 PNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQN 300
P++ SFEFFPPKT+ G NLL R++RM A +P F ITWGAGGST++ +LD+A Q
Sbjct: 13 PDERFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFITITWGAGGSTSEKSLDLAATCQK 72
Query: 301 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 441
VG+ T++HLTCTN E ID+AL K+NG++N+LALRGDPP ++
Sbjct: 73 EVGITTVLHLTCTNTNKEIIDEALARAKANGIRNILALRGDPPRAEE 119
[84][TOP]
>UniRef100_B8BVS6 Methylenetetrahydrofolate reductase n=1 Tax=Thalassiosira
pseudonana CCMP1335 RepID=B8BVS6_THAPS
Length = 383
Score = 127 bits (318), Expect = 5e-28
Identities = 66/139 (47%), Positives = 92/139 (66%), Gaps = 6/139 (4%)
Frame = +1
Query: 94 KIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPS-FXDITWGAGGSTADV 270
KI + D S E+FPP+T+ GV NL RMDRM+ ++ + + D+TWGAGGSTAD+
Sbjct: 12 KIIDLLQRDTEIAHVSLEYFPPRTDQGVKNLHARMDRMLVNTNALYTDMTWGAGGSTADL 71
Query: 271 TLDIAKKMQNTVGVETMMHLTCTNM-----PVEKIDDALETIKSNGLQNVLALRGDPPHG 435
+L++A T G + MHLTCTNM PV+ + DAL+ G++N++ALRGDPP G
Sbjct: 72 SLELALHAHKT-GHVSNMHLTCTNMEKDGDPVKAVHDALQQAYDGGIRNIVALRGDPPEG 130
Query: 436 QDKFVQVEGGFACARDLVK 492
+ ++ EGGF+CA DLVK
Sbjct: 131 EKEWTATEGGFSCALDLVK 149
[85][TOP]
>UniRef100_Q5A5S8 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5A5S8_CANAL
Length = 640
Score = 127 bits (318), Expect = 5e-28
Identities = 64/128 (50%), Positives = 87/128 (67%)
Frame = +1
Query: 109 AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAK 288
A+ P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 9 ASLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFVTVTWGAGGSTSEKSLDLAA 68
Query: 289 KMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGF 468
QN +G+ T++HLTCTN E ID AL K+ G++N+LALRGDPP ++ + F
Sbjct: 69 TCQNEIGITTVLHLTCTNTNKEVIDQALSRAKAAGVRNILALRGDPPRTEEYWTP-NCDF 127
Query: 469 ACARDLVK 492
A DLVK
Sbjct: 128 NGAVDLVK 135
[86][TOP]
>UniRef100_C4YKV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=C4YKV3_CANAL
Length = 640
Score = 127 bits (318), Expect = 5e-28
Identities = 64/128 (50%), Positives = 87/128 (67%)
Frame = +1
Query: 109 AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAK 288
A+ P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 9 ASLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFVTVTWGAGGSTSEKSLDLAA 68
Query: 289 KMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGF 468
QN +G+ T++HLTCTN E ID AL K+ G++N+LALRGDPP ++ + F
Sbjct: 69 TCQNEIGITTVLHLTCTNTNKEVIDQALSKAKAAGVRNILALRGDPPRTEEYWTP-NCDF 127
Query: 469 ACARDLVK 492
A DLVK
Sbjct: 128 NGAVDLVK 135
[87][TOP]
>UniRef100_Q6BM19 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=Q6BM19_DEBHA
Length = 642
Score = 126 bits (317), Expect = 7e-28
Identities = 64/127 (50%), Positives = 88/127 (69%)
Frame = +1
Query: 112 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKK 291
A P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 10 ALKPHERFVSFEFFPPKTDTGFRNLLARLNRMSALNPLFITVTWGAGGSTSEKSLDLAAT 69
Query: 292 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFA 471
Q +G+ T++HLTCTN E ID+ALE K G++N+LALRGDPP ++ ++ + F
Sbjct: 70 CQKEIGLTTVLHLTCTNTNKEIIDNALEKAKEQGIRNILALRGDPPRTEEYWIP-DCDFN 128
Query: 472 CARDLVK 492
A DLVK
Sbjct: 129 NAVDLVK 135
[88][TOP]
>UniRef100_A5DZ35 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DZ35_LODEL
Length = 622
Score = 126 bits (317), Expect = 7e-28
Identities = 62/124 (50%), Positives = 86/124 (69%)
Frame = +1
Query: 121 PNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQN 300
P++ SFEFF PKT+ G NLL R++R++A +P F +TWGAGGST++ +LD+A QN
Sbjct: 13 PDEKFISFEFFSPKTDSGFRNLLARLNRLLAFNPLFITVTWGAGGSTSEKSLDLAATCQN 72
Query: 301 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACAR 480
+G+ T++HLTCTN E ID AL K+NG++N+LALRGDPP ++ + F A
Sbjct: 73 KIGINTVLHLTCTNTDKEIIDSALARAKANGIRNILALRGDPPRTEEYWTP-NCEFNNAV 131
Query: 481 DLVK 492
DLVK
Sbjct: 132 DLVK 135
[89][TOP]
>UniRef100_A5DE00 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DE00_PICGU
Length = 642
Score = 126 bits (316), Expect = 9e-28
Identities = 66/138 (47%), Positives = 91/138 (65%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
M V++KI+ D SFEFFPPKT+ G NLL R+ RM A +P F +TWGAGGS
Sbjct: 1 MSVVQKINSLGPQDR---FISFEFFPPKTDTGFRNLLARLHRMSALNPLFITVTWGAGGS 57
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
T++ +LD+A Q +G+ T++HLTCTN + ID+AL+ K NG++N+LALRGDPP +
Sbjct: 58 TSEKSLDLAITCQKELGLTTVLHLTCTNTNKDIIDNALQRAKENGIRNILALRGDPPRTE 117
Query: 439 DKFVQVEGGFACARDLVK 492
+ + + F A DLVK
Sbjct: 118 EYWTP-DCDFYSAVDLVK 134
[90][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 125 bits (313), Expect = 2e-27
Identities = 67/140 (47%), Positives = 85/140 (60%), Gaps = 3/140 (2%)
Frame = +1
Query: 79 MKVIEKIHE---AAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGA 249
M++ +K+ + AA + K FSFEFF PKT GV NL +RMDRM P F DITW A
Sbjct: 1 MRISQKLKQRAGAADEEQPKASFSFEFFVPKTLQGVQNLYDRMDRMYQTQPEFIDITWNA 60
Query: 250 GGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 429
GG + T ++ Q +G+ET MHLTCTNM +D+ALE G +N+LALRGDPP
Sbjct: 61 GGRLSQRTSELVATSQGVLGLETCMHLTCTNMSTALVDEALERAYEAGCENILALRGDPP 120
Query: 430 HGQDKFVQVEGGFACARDLV 489
Q + GGF A+DLV
Sbjct: 121 L-QGTWEPCAGGFRYAKDLV 139
[91][TOP]
>UniRef100_C5DPF1 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5DPF1_ZYGRC
Length = 650
Score = 125 bits (313), Expect = 2e-27
Identities = 61/101 (60%), Positives = 71/101 (70%)
Frame = +1
Query: 139 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVET 318
S EFFPPKTE G NLLERM+RM A P F +TWGAGGSTA+ TL++A Q + +
Sbjct: 16 SLEFFPPKTETGKQNLLERMERMTALGPLFATVTWGAGGSTAEKTLELASLAQKNLNLPI 75
Query: 319 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 441
MHLTCTNM IDDAL K+ G+ N+LALRGDPP GQD
Sbjct: 76 CMHLTCTNMDRNIIDDALTRCKAAGIHNILALRGDPPIGQD 116
[92][TOP]
>UniRef100_Q6CEM7 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CEM7_YARLI
Length = 625
Score = 124 bits (312), Expect = 3e-27
Identities = 67/138 (48%), Positives = 86/138 (62%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
M I K+ A P++ FS EFFPPKT++G+ N R+ RM A P F ITWGAGGS
Sbjct: 1 MSTITKL--IAGLKPDEKFFSLEFFPPKTQNGMANFRARLARMAALKPLFITITWGAGGS 58
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
TA +LDIA + Q ++G++ +HLTCTNM ID ALE G+ N+LALRGDPP G+
Sbjct: 59 TAKKSLDIASECQ-SMGLDVCLHLTCTNMDPALIDQALEAASKAGICNILALRGDPPRGE 117
Query: 439 DKFVQVEGGFACARDLVK 492
+ + F A DLVK
Sbjct: 118 EYWQPASPEFQHAADLVK 135
[93][TOP]
>UniRef100_Q752W6 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q752W6_ASHGO
Length = 635
Score = 124 bits (310), Expect = 4e-27
Identities = 63/126 (50%), Positives = 81/126 (64%)
Frame = +1
Query: 115 SDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKM 294
S+ N+ S EFFPPKT+ G NLL R++RM A P F +TWGAGGSTA+ TL++A
Sbjct: 9 SELNRPSLSLEFFPPKTDSGKSNLLARIERMSAMDPLFITVTWGAGGSTAEKTLELAALA 68
Query: 295 QNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFAC 474
Q + + MHLTCTNM +D AL K G++N+LALRGD P D+ V+GGF
Sbjct: 69 QRELNIPVCMHLTCTNMDRTILDKALMRAKEAGIRNILALRGDMPLAADEEEHVDGGFLY 128
Query: 475 ARDLVK 492
A DLV+
Sbjct: 129 AIDLVR 134
[94][TOP]
>UniRef100_C4Y9Q4 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y9Q4_CLAL4
Length = 601
Score = 122 bits (306), Expect = 1e-26
Identities = 65/138 (47%), Positives = 90/138 (65%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
M V+E+I A P++ SFEFFPPKT+ G NLL R+ RM +P F +TWGAGGS
Sbjct: 1 MSVVERIQ---ALGPDEKFCSFEFFPPKTDAGFRNLLARLHRMRDLNPLFVSVTWGAGGS 57
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
T++ +L++A Q +G+ T++HLTCTN IDDAL K+ G++N+LALRGDPP +
Sbjct: 58 TSEKSLELAVTCQQLLGISTVLHLTCTNTNKAIIDDALSRAKAAGIRNILALRGDPPRTR 117
Query: 439 DKFVQVEGGFACARDLVK 492
+ + E F A DLV+
Sbjct: 118 EYWTP-ECSFRTAVDLVR 134
[95][TOP]
>UniRef100_C4R2L4 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2L4_PICPG
Length = 596
Score = 120 bits (301), Expect = 5e-26
Identities = 64/137 (46%), Positives = 89/137 (64%)
Frame = +1
Query: 82 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGST 261
K+I+KI E +SFEFFPPKT++G+ NLL R+ RM +P F +TWGAGG+T
Sbjct: 3 KIIDKIKELKGEP----FYSFEFFPPKTDNGLRNLLARLGRMSMLNPLFVTVTWGAGGTT 58
Query: 262 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 441
+ TLD+A Q + + T +HLTCTN + ID+AL+ NG++N+LALRGDPP +
Sbjct: 59 SSKTLDLAITCQKDLDLTTCIHLTCTNTSKKLIDNALKAAYDNGIKNILALRGDPPR-EA 117
Query: 442 KFVQVEGGFACARDLVK 492
+ V V+ F A DLV+
Sbjct: 118 QEVAVDQDFKYAIDLVR 134
[96][TOP]
>UniRef100_A7TRT4 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TRT4_VANPO
Length = 645
Score = 120 bits (301), Expect = 5e-26
Identities = 58/101 (57%), Positives = 73/101 (72%)
Frame = +1
Query: 139 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVET 318
S EFFPPKTE G NLLERM RM A P F +TWGAGG+TA+ TL++A +N++ +
Sbjct: 17 SLEFFPPKTEIGKRNLLERMGRMSAMDPLFVTVTWGAGGTTAEKTLELATLAENSLNLNV 76
Query: 319 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 441
+HLTCTNM ID+ALE K G++N+LALRGDPP G+D
Sbjct: 77 CIHLTCTNMSRGIIDEALEACKKIGIRNILALRGDPPIGED 117
[97][TOP]
>UniRef100_Q08QG9 Methylenetetrahydrofolate reductase n=1 Tax=Stigmatella aurantiaca
DW4/3-1 RepID=Q08QG9_STIAU
Length = 327
Score = 120 bits (300), Expect = 6e-26
Identities = 54/125 (43%), Positives = 81/125 (64%)
Frame = +1
Query: 118 DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQ 297
+P+ FSFEFFPPKT++G NLL+ ++ + P F +T+GAGGST + TL + +++
Sbjct: 45 NPSNPCFSFEFFPPKTDEGTENLLKTVEELAPLEPGFVSVTYGAGGSTREKTLGLVTRIK 104
Query: 298 NTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACA 477
T G+E+M HLTC +++ + L+ +++ L NVL LRGDPP GQ F GGF A
Sbjct: 105 QTTGIESMAHLTCVGHTRDELREVLQQLEAAKLDNVLVLRGDPPRGQTTFAPTPGGFRYA 164
Query: 478 RDLVK 492
+LV+
Sbjct: 165 SELVE 169
[98][TOP]
>UniRef100_P46151 Methylenetetrahydrofolate reductase 1 n=1 Tax=Saccharomyces
cerevisiae RepID=MTHR1_YEAST
Length = 657
Score = 119 bits (299), Expect = 8e-26
Identities = 67/137 (48%), Positives = 83/137 (60%), Gaps = 2/137 (1%)
Frame = +1
Query: 88 IEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTAD 267
I ++ A AS S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 268 VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD-- 441
TL +A Q T+ + MHLTCTN IDDAL+ + G++N+LALRGDPP G+D
Sbjct: 59 KTLTLASLAQQTLNIPVCMHLTCTNTEKAIIDDALDRCYNAGIRNILALRGDPPIGEDWL 118
Query: 442 KFVQVEGGFACARDLVK 492
E F A DLV+
Sbjct: 119 DSQSNESPFKYAVDLVR 135
[99][TOP]
>UniRef100_C7GU28 Met12p n=2 Tax=Saccharomyces cerevisiae RepID=C7GU28_YEAS2
Length = 657
Score = 119 bits (298), Expect = 1e-25
Identities = 67/137 (48%), Positives = 83/137 (60%), Gaps = 2/137 (1%)
Frame = +1
Query: 88 IEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTAD 267
I ++ A AS S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 268 VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD-- 441
TL +A Q T+ + MHLTCTN IDDAL+ + G++N+LALRGDPP G+D
Sbjct: 59 KTLALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPPIGEDWL 118
Query: 442 KFVQVEGGFACARDLVK 492
E F A DLV+
Sbjct: 119 DSQSNESPFKYAVDLVR 135
[100][TOP]
>UniRef100_B5VTD9 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VTD9_YEAS6
Length = 657
Score = 119 bits (298), Expect = 1e-25
Identities = 67/137 (48%), Positives = 83/137 (60%), Gaps = 2/137 (1%)
Frame = +1
Query: 88 IEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTAD 267
I ++ A AS S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 268 VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD-- 441
TL +A Q T+ + MHLTCTN IDDAL+ + G++N+LALRGDPP G+D
Sbjct: 59 KTLALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPPIGEDWL 118
Query: 442 KFVQVEGGFACARDLVK 492
E F A DLV+
Sbjct: 119 DSQSNESPFKYAVDLVR 135
[101][TOP]
>UniRef100_B3LL40 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LL40_YEAS1
Length = 657
Score = 119 bits (298), Expect = 1e-25
Identities = 67/137 (48%), Positives = 83/137 (60%), Gaps = 2/137 (1%)
Frame = +1
Query: 88 IEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTAD 267
I ++ A AS S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 268 VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD-- 441
TL +A Q T+ + MHLTCTN IDDAL+ + G++N+LALRGDPP G+D
Sbjct: 59 KTLALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPPIGEDWL 118
Query: 442 KFVQVEGGFACARDLVK 492
E F A DLV+
Sbjct: 119 DSQSNESPFKYAVDLVR 135
[102][TOP]
>UniRef100_A6ZWM3 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae YJM789 RepID=A6ZWM3_YEAS7
Length = 441
Score = 119 bits (298), Expect = 1e-25
Identities = 67/137 (48%), Positives = 83/137 (60%), Gaps = 2/137 (1%)
Frame = +1
Query: 88 IEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTAD 267
I ++ A AS S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 268 VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD-- 441
TL +A Q T+ + MHLTCTN IDDAL+ + G++N+LALRGDPP G+D
Sbjct: 59 KTLALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPPIGEDWL 118
Query: 442 KFVQVEGGFACARDLVK 492
E F A DLV+
Sbjct: 119 DSQSNESPFKYAVDLVR 135
[103][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 119 bits (298), Expect = 1e-25
Identities = 62/123 (50%), Positives = 79/123 (64%), Gaps = 1/123 (0%)
Frame = +1
Query: 127 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFXDITWGAGGSTADVTLDIAKKMQNT 303
KV +S+EFFPPKT GV NL R+DRM P F D+TWGAGG+++++T I +Q
Sbjct: 15 KVTYSYEFFPPKTSTGVQNLYNRIDRMKTWGRPMFVDVTWGAGGTSSELTPGIVNVIQTD 74
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
V+T MHLTCTNM E ID AL+ G +N+LALRGDP D + + E GF A D
Sbjct: 75 FEVDTCMHLTCTNMSTEMIDAALKRAHETGCRNILALRGDPVKDTD-WTEGESGFRYASD 133
Query: 484 LVK 492
LV+
Sbjct: 134 LVR 136
[104][TOP]
>UniRef100_Q6FNS2 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FNS2_CANGA
Length = 645
Score = 118 bits (296), Expect = 2e-25
Identities = 65/131 (49%), Positives = 83/131 (63%), Gaps = 5/131 (3%)
Frame = +1
Query: 115 SDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKM 294
SD + + S EFFPPKTE G NLLERM+RM A P F +TWGAGGST++ TL++A+
Sbjct: 8 SDRDGPLISLEFFPPKTESGKRNLLERMERMSALDPLFITVTWGAGGSTSEKTLELAQIA 67
Query: 295 QNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP---HGQDKFVQVEGG 465
Q + V MHLTCTNM I +AL+ +S G++N+LALRGD P DK + G
Sbjct: 68 QRDLNVPICMHLTCTNMDTTLIKEALDACRSYGIKNILALRGDAPIEDQWDDKTINSSEG 127
Query: 466 --FACARDLVK 492
F A DLV+
Sbjct: 128 PEFRYAVDLVR 138
[105][TOP]
>UniRef100_C1XWC8 Methylenetetrahydrofolate reductase n=1 Tax=Meiothermus silvanus
DSM 9946 RepID=C1XWC8_9DEIN
Length = 294
Score = 118 bits (295), Expect = 2e-25
Identities = 59/132 (44%), Positives = 83/132 (62%)
Frame = +1
Query: 94 KIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVT 273
KIH A P K +FSFEFFPPKTE+G L + + P+F +T+GAGGS T
Sbjct: 2 KIHTQFA--PGKPLFSFEFFPPKTEEGEAQLFRTLHILKPLQPAFVSVTYGAGGSARGKT 59
Query: 274 LDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQ 453
++ ++++ VG+E M HLTC E+I + LE ++ G +N++A+RGDPP GQ +F
Sbjct: 60 VEWVERIKREVGLEVMAHLTCVGATREEIGEVLEQLRQVGAENLMAVRGDPPKGQREFRP 119
Query: 454 VEGGFACARDLV 489
VEGGF A +LV
Sbjct: 120 VEGGFRYASELV 131
[106][TOP]
>UniRef100_A6RQJ7 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6RQJ7_BOTFB
Length = 663
Score = 117 bits (292), Expect = 5e-25
Identities = 62/121 (51%), Positives = 80/121 (66%), Gaps = 1/121 (0%)
Frame = +1
Query: 82 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGS 258
K+ EKI AA P+ FS EFFPPKT G NL R+DRM A P F +TWGAGGS
Sbjct: 3 KITEKI---AALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGS 59
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
TA +L++A+ Q +G+ T +HLTCTNM +D ALE K+ G++N+LALRGDPP +
Sbjct: 60 TATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSE 119
Query: 439 D 441
+
Sbjct: 120 E 120
[107][TOP]
>UniRef100_B4UHX4 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter sp. K
RepID=B4UHX4_ANASK
Length = 300
Score = 116 bits (290), Expect = 9e-25
Identities = 56/126 (44%), Positives = 80/126 (63%)
Frame = +1
Query: 112 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKK 291
A + + +FSFEFFPPKT+DGV L E ++ + P++ +T+GAGGST T+++ K+
Sbjct: 10 ARERGEPIFSFEFFPPKTDDGVRGLFETVEALRPLGPAYVSVTYGAGGSTRAKTIELVKR 69
Query: 292 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFA 471
++ VE M H+TC ++I L+ + G+QNVLALRGDPP GQ FV GFA
Sbjct: 70 LKRDAEVEAMAHVTCVGASRDEIAAVLDEVAEAGIQNVLALRGDPPRGQGAFVPHPDGFA 129
Query: 472 CARDLV 489
A +LV
Sbjct: 130 HASELV 135
[108][TOP]
>UniRef100_B6QFH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QFH8_PENMQ
Length = 710
Score = 116 bits (290), Expect = 9e-25
Identities = 61/121 (50%), Positives = 82/121 (67%), Gaps = 1/121 (0%)
Frame = +1
Query: 82 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGS 258
K+ EKI AA P+ FS EFFPPKT+ G VNL R++RM A P F +TWGAGG+
Sbjct: 3 KITEKI---AALPPDSNYFSLEFFPPKTQMGSVNLQARLERMAQALRPLFVTVTWGAGGT 59
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
TA +L++A+ Q + + T +HLTCTNM ID+ALE K+ G++N+LALRGDPP +
Sbjct: 60 TAAKSLELAEICQRQLQLTTCLHLTCTNMTRSLIDEALEQAKALGIRNILALRGDPPRSE 119
Query: 439 D 441
+
Sbjct: 120 E 120
[109][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 116 bits (290), Expect = 9e-25
Identities = 54/96 (56%), Positives = 69/96 (71%)
Frame = +1
Query: 205 MVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIK 384
M A P F DITW AGG T+D+T ++ K Q +G+ET MHLTCTNMP EK+D AL+ K
Sbjct: 1 MRALGPEFIDITWNAGGRTSDLTSEMVKTCQGLIGIETCMHLTCTNMPREKVDTALKEAK 60
Query: 385 SNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
+G +N+LALRGDPP G+D++ VEGGF DLV+
Sbjct: 61 EHGCRNILALRGDPPMGKDEWEAVEGGFVHGIDLVR 96
[110][TOP]
>UniRef100_A7E9M9 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7E9M9_SCLS1
Length = 663
Score = 116 bits (290), Expect = 9e-25
Identities = 62/121 (51%), Positives = 79/121 (65%), Gaps = 1/121 (0%)
Frame = +1
Query: 82 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGS 258
K+ EKI AA P+ FS EFFPPKT G NL R+DRM A P F +TWGAGGS
Sbjct: 3 KITEKI---AALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGS 59
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
TA +L++A+ Q +G+ T +HLTCTNM +D ALE K+ G++N+LALRGDPP
Sbjct: 60 TATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSD 119
Query: 439 D 441
+
Sbjct: 120 E 120
[111][TOP]
>UniRef100_B9XQY3 Methylenetetrahydrofolate reductase n=1 Tax=bacterium Ellin514
RepID=B9XQY3_9BACT
Length = 303
Score = 115 bits (289), Expect = 1e-24
Identities = 61/138 (44%), Positives = 88/138 (63%), Gaps = 1/138 (0%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLER-MDRMVAHSPSFXDITWGAGG 255
M+ I I+ AA +D ++ V SFEFFPPKT++G LLE+ + ++ P F +T+GAGG
Sbjct: 7 MQFIRDIY-AAKADAHQPVISFEFFPPKTDEGDRALLEKTIPALLRLKPDFCSVTYGAGG 65
Query: 256 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 435
T D TL I ++Q + TM+HLTC N E++ D +E +S G++N+LALRGDPP G
Sbjct: 66 GTRDKTLMIVDRIQREHQLPTMLHLTCVNATREQLRDVIEQARSLGVKNILALRGDPPGG 125
Query: 436 QDKFVQVEGGFACARDLV 489
+F +GGF + LV
Sbjct: 126 NGEFKMTDGGFEYSHQLV 143
[112][TOP]
>UniRef100_B4D0K5 Methylenetetrahydrofolate reductase n=1 Tax=Chthoniobacter flavus
Ellin428 RepID=B4D0K5_9BACT
Length = 297
Score = 115 bits (289), Expect = 1e-24
Identities = 64/138 (46%), Positives = 87/138 (63%), Gaps = 1/138 (0%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLER-MDRMVAHSPSFXDITWGAGG 255
M+ I I+ A A + V S EFFP KTE+G NLLE+ + +++ P+F +T+GAGG
Sbjct: 1 MQFIRDIY-AEARLAGRPVLSLEFFPTKTEEGERNLLEKTLPDLMSIKPAFCSVTYGAGG 59
Query: 256 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 435
T D TL I ++Q + MMHLTC N E++ L+ K G+QN+LALRGDPP G
Sbjct: 60 GTRDKTLGIVDRIQRHHNLPAMMHLTCVNSTREELGHVLDEAKGRGIQNILALRGDPPSG 119
Query: 436 QDKFVQVEGGFACARDLV 489
D FV+ EGGF +R+LV
Sbjct: 120 GD-FVKTEGGFEFSRELV 136
[113][TOP]
>UniRef100_B8NQE8 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus flavus
NRRL3357 RepID=B8NQE8_ASPFN
Length = 738
Score = 115 bits (289), Expect = 1e-24
Identities = 73/162 (45%), Positives = 95/162 (58%), Gaps = 9/162 (5%)
Frame = +1
Query: 34 YPLSLSLASIKD*NKM-KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV 210
Y LS + A KM K+ +KI AA P+ FS EFFPPKT+ G NL R++RM
Sbjct: 34 YHLSRNFAGTDSGIKMEKITDKI---AALPPDANYFSLEFFPPKTQMGFANLQARLERMA 90
Query: 211 -AHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKS 387
A P F +TWGAGGSTA +L++A+ Q + + T +HLTCTNM +D+ALE K
Sbjct: 91 QALRPLFVTVTWGAGGSTAQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKV 150
Query: 388 NGLQNVLALRGDPP-------HGQDKFVQVEGGFACARDLVK 492
G++N+LALRGDPP HG+D F A DLV+
Sbjct: 151 LGIRNILALRGDPPRSEEYNMHGED---DSNRDFTFAVDLVR 189
[114][TOP]
>UniRef100_A4HQF9 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania braziliensis
RepID=A4HQF9_LEIBR
Length = 309
Score = 115 bits (288), Expect = 2e-24
Identities = 58/130 (44%), Positives = 83/130 (63%), Gaps = 2/130 (1%)
Frame = +1
Query: 109 AASDPNKVVFSFEFFPPKTEDGVVNLLE-RMDRMVAHSPSFXDITWGAGGSTADVTLDIA 285
AA D NK S+EF+PP++E N ++ ++ + SP F D+TWGAGG T++ T+ +
Sbjct: 10 AAEDANKWYTSYEFYPPRSEKAEENFMKVQIPNFMRQSPVFLDLTWGAGGRTSETTMRLC 69
Query: 286 KKMQNTV-GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEG 462
K +QN MH+TCTNM + I + L+ K +G++N+LALRGDPP G D+F
Sbjct: 70 KDLQNAYPDTPINMHITCTNMSHDLIKETLDFAKEHGIRNILALRGDPPRG-DEFQSNPE 128
Query: 463 GFACARDLVK 492
GF CARDLV+
Sbjct: 129 GFTCARDLVR 138
[115][TOP]
>UniRef100_Q2ILB5 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter
dehalogenans 2CP-C RepID=Q2ILB5_ANADE
Length = 300
Score = 114 bits (286), Expect = 3e-24
Identities = 56/126 (44%), Positives = 78/126 (61%)
Frame = +1
Query: 112 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKK 291
A + + +FSFEFFPPKT+DGV L E ++ + P++ +T+GAGGST T+D+ K+
Sbjct: 10 ARERGEPIFSFEFFPPKTDDGVRGLFETVEALRPLGPAYVSVTYGAGGSTRAKTIDLVKR 69
Query: 292 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFA 471
++ VE M H+TC E+I L+ + G+QNVLALRGD P GQ FV GF
Sbjct: 70 LKRDAEVEAMAHVTCVGASREEIAAVLDEVADAGIQNVLALRGDAPRGQSAFVPHPDGFT 129
Query: 472 CARDLV 489
A +LV
Sbjct: 130 HASELV 135
[116][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 114 bits (286), Expect = 3e-24
Identities = 69/145 (47%), Positives = 89/145 (61%), Gaps = 8/145 (5%)
Frame = +1
Query: 82 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGS 258
K+ +KI AA PN+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPNENYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGS 59
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP--- 429
TA +L++A+ Q + + T +HLTCTNM ID+ALE K G++N+LALRGDPP
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSE 119
Query: 430 ----HGQDKFVQVEGGFACARDLVK 492
HG+D F A DLV+
Sbjct: 120 EYNTHGED---DSNKDFTFAVDLVR 141
[117][TOP]
>UniRef100_C8V780 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5AU15] n=2 Tax=Emericella
nidulans RepID=C8V780_EMENI
Length = 684
Score = 114 bits (286), Expect = 3e-24
Identities = 68/144 (47%), Positives = 87/144 (60%), Gaps = 9/144 (6%)
Frame = +1
Query: 88 IEKI-HEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGST 261
+EKI H+ AA P FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKITHKIAALPPGANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST 60
Query: 262 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP---- 429
A +L++A+ Q + + T +HLTCTNM +D ALE K G++N+LALRGDPP
Sbjct: 61 AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEE 120
Query: 430 ---HGQDKFVQVEGGFACARDLVK 492
HG+D F A DLV+
Sbjct: 121 YNMHGED---DSNKDFTFAVDLVR 141
[118][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 114 bits (286), Expect = 3e-24
Identities = 69/145 (47%), Positives = 89/145 (61%), Gaps = 8/145 (5%)
Frame = +1
Query: 82 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGS 258
K+ +KI AA PN+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPNENYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGS 59
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP--- 429
TA +L++A+ Q + + T +HLTCTNM ID+ALE K G++N+LALRGDPP
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSE 119
Query: 430 ----HGQDKFVQVEGGFACARDLVK 492
HG+D F A DLV+
Sbjct: 120 EYNTHGED---DSNKDFTFAVDLVR 141
[119][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1CZX0_NEOFI
Length = 716
Score = 114 bits (286), Expect = 3e-24
Identities = 69/145 (47%), Positives = 89/145 (61%), Gaps = 8/145 (5%)
Frame = +1
Query: 82 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGS 258
K+ +KI AA PN+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 30 KITDKI---AALPPNENYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGS 86
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP--- 429
TA +L++A+ Q + + T +HLTCTNM ID+ALE K G++N+LALRGDPP
Sbjct: 87 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSE 146
Query: 430 ----HGQDKFVQVEGGFACARDLVK 492
HG+D F A DLV+
Sbjct: 147 EYNMHGED---DSNKDFTFAVDLVR 168
[120][TOP]
>UniRef100_B8JEQ3 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter
dehalogenans 2CP-1 RepID=B8JEQ3_ANAD2
Length = 300
Score = 114 bits (285), Expect = 3e-24
Identities = 55/126 (43%), Positives = 79/126 (62%)
Frame = +1
Query: 112 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKK 291
A + + +FSFEFFPPKT+DGV L E ++ + P++ +T+GAGGST T+++ K+
Sbjct: 10 ARERGEPIFSFEFFPPKTDDGVRGLFETVEALRPLGPAYVSVTYGAGGSTRAKTIELVKR 69
Query: 292 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFA 471
++ VE M H+TC ++I L+ + G+QNVLALRGDPP GQ FV GF
Sbjct: 70 LKRDAEVEAMAHVTCVGASRDEIAAVLDEVAEAGIQNVLALRGDPPRGQGGFVPHPDGFT 129
Query: 472 CARDLV 489
A +LV
Sbjct: 130 HASELV 135
[121][TOP]
>UniRef100_A7HDS2 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter sp.
Fw109-5 RepID=A7HDS2_ANADF
Length = 300
Score = 114 bits (285), Expect = 3e-24
Identities = 56/126 (44%), Positives = 79/126 (62%)
Frame = +1
Query: 112 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKK 291
A + + VFSFEFFPPKT+DGV L E ++ + +P++ +T+GAGGST TL++ K+
Sbjct: 10 ARERGEPVFSFEFFPPKTDDGVRQLFETVEALRPLAPAYVSVTYGAGGSTRQRTLELVKR 69
Query: 292 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFA 471
++ VE M HLTC E++ L+ + G+QNVLALRGDPP G+ F GF
Sbjct: 70 LKRDTEVEAMAHLTCVGASREELAAVLDELAEAGIQNVLALRGDPPRGETSFSPHPEGFR 129
Query: 472 CARDLV 489
A +LV
Sbjct: 130 YASELV 135
[122][TOP]
>UniRef100_C5GI01 Methylenetetrahydrofolate reductase n=2 Tax=Ajellomyces
dermatitidis RepID=C5GI01_AJEDR
Length = 713
Score = 114 bits (285), Expect = 3e-24
Identities = 66/141 (46%), Positives = 88/141 (62%), Gaps = 6/141 (4%)
Frame = +1
Query: 88 IEKIHEAAASDP-NKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGST 261
+EKI + A+ P N FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIAALPRNANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 262 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 441
A +L++A+ Q +G+ T +HLTCTNM +D AL K+ G++N+LALRGDPP ++
Sbjct: 61 AAKSLELAEICQRQLGLTTCLHLTCTNMNRSLVDHALSEAKALGIRNILALRGDPPRSEE 120
Query: 442 KFVQVEG----GFACARDLVK 492
+ E F A DLVK
Sbjct: 121 YNIDGEDDSNKDFTYAVDLVK 141
[123][TOP]
>UniRef100_C4JM22 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JM22_UNCRE
Length = 709
Score = 114 bits (285), Expect = 3e-24
Identities = 66/141 (46%), Positives = 88/141 (62%), Gaps = 6/141 (4%)
Frame = +1
Query: 88 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGST 261
+EKI + A+ P FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIAALPEDANFFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 262 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 441
A +L++A+ Q +G+ T +HLTCTNM IDDAL+ K+ G++N+LALRGDPP +
Sbjct: 61 ASKSLELAEICQRQLGLTTCLHLTCTNMNRALIDDALDEAKALGIRNILALRGDPPRSDE 120
Query: 442 KFVQVEG----GFACARDLVK 492
+ E F A DLV+
Sbjct: 121 YNLAGEDDSNKDFTYAIDLVR 141
[124][TOP]
>UniRef100_B8MDD4 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8MDD4_TALSN
Length = 713
Score = 114 bits (285), Expect = 3e-24
Identities = 60/121 (49%), Positives = 80/121 (66%), Gaps = 1/121 (0%)
Frame = +1
Query: 82 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGS 258
K+ EKI AA P FS EFFPPKT+ G VNL R++RM P F +TWGAGG+
Sbjct: 3 KITEKI---AALPPGSNYFSLEFFPPKTQMGSVNLQARLERMAQVLRPLFVTVTWGAGGT 59
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
TA +L++A+ Q + + T +HLTCTNM ID+ALE K+ G++N+LALRGDPP +
Sbjct: 60 TAAKSLELAEICQRQLQLTTCLHLTCTNMTRSLIDEALEQAKALGIKNILALRGDPPRSE 119
Query: 439 D 441
+
Sbjct: 120 E 120
[125][TOP]
>UniRef100_Q2UA39 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus oryzae
RepID=Q2UA39_ASPOR
Length = 690
Score = 114 bits (284), Expect = 4e-24
Identities = 67/145 (46%), Positives = 88/145 (60%), Gaps = 8/145 (5%)
Frame = +1
Query: 82 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGS 258
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGS 59
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP--- 429
TA +L++A+ Q + + T +HLTCTNM +D+ALE K G++N+LALRGDPP
Sbjct: 60 TAQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSE 119
Query: 430 ----HGQDKFVQVEGGFACARDLVK 492
HG+D F A DLV+
Sbjct: 120 EYNMHGED---DSNRDFTFAVDLVR 141
[126][TOP]
>UniRef100_Q2HBA5 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2HBA5_CHAGB
Length = 643
Score = 113 bits (283), Expect = 6e-24
Identities = 66/147 (44%), Positives = 90/147 (61%), Gaps = 8/147 (5%)
Frame = +1
Query: 76 KMKVIEKIHEAAASDP-NKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGA 249
K ++KI + A+ P + FS EFFPPKT G NL R+DRM A P F ++TWGA
Sbjct: 16 KSHAMDKITDKIAALPAGQDYFSLEFFPPKTAMGFSNLRSRLDRMARALRPLFVNVTWGA 75
Query: 250 GGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 429
GGSTA +L++A+ Q +G+ T +HLTCTNM ID AL+ K+ G++N+LALRGDPP
Sbjct: 76 GGSTATKSLELAEICQRELGLTTCLHLTCTNMSRRLIDKALDDAKALGIRNILALRGDPP 135
Query: 430 H------GQDKFVQVEGGFACARDLVK 492
+ + E F+ A DLV+
Sbjct: 136 RRAEYRDANEPEPEEEEEFSWAVDLVR 162
[127][TOP]
>UniRef100_Q6CR34 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CR34_KLULA
Length = 649
Score = 113 bits (282), Expect = 8e-24
Identities = 58/118 (49%), Positives = 76/118 (64%)
Frame = +1
Query: 139 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVET 318
S EFFPPKTE G NLL RM+RM A +P F +TW AGG+TA TL++A Q + V
Sbjct: 27 SLEFFPPKTEPGKRNLLARMERMCALNPLFITVTWAAGGTTAGKTLELATIAQRELNVPV 86
Query: 319 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
MHLTCTNM + ID+AL+ + ++N+LALRGDP G++ + F A DLV+
Sbjct: 87 CMHLTCTNMNKDIIDEALKAARDADIRNILALRGDPAIGEEWSPDADTEFKYAVDLVR 144
[128][TOP]
>UniRef100_C6HED8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6HED8_AJECH
Length = 713
Score = 113 bits (282), Expect = 8e-24
Identities = 65/141 (46%), Positives = 88/141 (62%), Gaps = 6/141 (4%)
Frame = +1
Query: 88 IEKIHEAAAS-DPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGST 261
+EKI + A+ P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIANLPPDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 262 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 441
A +L++A+ Q +G+ T +HLTCTNM +D AL K+ G++N+LALRGDPP ++
Sbjct: 61 AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNILALRGDPPRSEE 120
Query: 442 KFVQVEG----GFACARDLVK 492
+ E F A DLVK
Sbjct: 121 YNIDGEDDSNKDFTWAVDLVK 141
[129][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 113 bits (282), Expect = 8e-24
Identities = 67/142 (47%), Positives = 91/142 (64%), Gaps = 5/142 (3%)
Frame = +1
Query: 82 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGS 258
K+ +KI EA D + FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KISDKI-EALPKDAH--YFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGS 59
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
TA +L++A+ Q +G+ T +HLTCTNM ID+ALE K+ G++N+LALRGDPP +
Sbjct: 60 TAARSLELAEICQRQLGLTTCLHLTCTNMNRTLIDEALEETKALGIRNILALRGDPPRSE 119
Query: 439 DKFVQVEG----GFACARDLVK 492
+ + E F+ A DLV+
Sbjct: 120 EYNIDGEDDSNKDFSHAVDLVR 141
[130][TOP]
>UniRef100_C0NTN2 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NTN2_AJECG
Length = 713
Score = 113 bits (282), Expect = 8e-24
Identities = 65/141 (46%), Positives = 88/141 (62%), Gaps = 6/141 (4%)
Frame = +1
Query: 88 IEKIHEAAAS-DPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGST 261
+EKI + A+ P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIANLPPDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 262 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 441
A +L++A+ Q +G+ T +HLTCTNM +D AL K+ G++N+LALRGDPP ++
Sbjct: 61 AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNILALRGDPPRSEE 120
Query: 442 KFVQVEG----GFACARDLVK 492
+ E F A DLVK
Sbjct: 121 YNIDGEDDSNKDFTWAVDLVK 141
[131][TOP]
>UniRef100_A6QT35 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6QT35_AJECN
Length = 712
Score = 113 bits (282), Expect = 8e-24
Identities = 65/141 (46%), Positives = 88/141 (62%), Gaps = 6/141 (4%)
Frame = +1
Query: 88 IEKIHEAAAS-DPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGST 261
+EKI + A+ P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIANLPPDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 262 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 441
A +L++A+ Q +G+ T +HLTCTNM +D AL K+ G++N+LALRGDPP ++
Sbjct: 61 AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNILALRGDPPRSEE 120
Query: 442 KFVQVEG----GFACARDLVK 492
+ E F A DLVK
Sbjct: 121 YNIDGEDDSNKDFTWAVDLVK 141
[132][TOP]
>UniRef100_B0SH77 Methylenetetrahydrofolate reductase n=2 Tax=Leptospira biflexa
serovar Patoc RepID=B0SH77_LEPBA
Length = 295
Score = 112 bits (281), Expect = 1e-23
Identities = 53/131 (40%), Positives = 77/131 (58%)
Frame = +1
Query: 97 IHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTL 276
+H + + SFEFFPPK E+ +L + + +P++ +T+GAGGST +T
Sbjct: 1 MHISEILGKKQTTISFEFFPPKNEEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRHLTH 60
Query: 277 DIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQV 456
D+ K+QN G+ + HLTC E+I D L+ +G+ N++ALRGDPP GQ F Q
Sbjct: 61 DLVVKLQNETGLTIVSHLTCVGSTKEEIGDILKRYDKSGIHNIMALRGDPPKGQQDFQQT 120
Query: 457 EGGFACARDLV 489
E GFA A +LV
Sbjct: 121 ENGFAYAGELV 131
[133][TOP]
>UniRef100_A2QUJ5 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QUJ5_ASPNC
Length = 699
Score = 112 bits (281), Expect = 1e-23
Identities = 67/145 (46%), Positives = 88/145 (60%), Gaps = 8/145 (5%)
Frame = +1
Query: 82 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGS 258
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGS 59
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP--- 429
TA +L++A+ Q + + T +HLTCTNM +D+ALE K G++N+LALRGDPP
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSE 119
Query: 430 ----HGQDKFVQVEGGFACARDLVK 492
HG+D F A DLV+
Sbjct: 120 EYNMHGED---DSNKDFTFAVDLVR 141
[134][TOP]
>UniRef100_C9S8T9 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S8T9_9PEZI
Length = 670
Score = 112 bits (280), Expect = 1e-23
Identities = 67/144 (46%), Positives = 87/144 (60%), Gaps = 7/144 (4%)
Frame = +1
Query: 82 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGS 258
K+ +KI AA N FS EFFPPKT G NL +R+DRM A P F ++TWGAGGS
Sbjct: 3 KITDKI---AALPANANYFSLEFFPPKTAMGFSNLRDRLDRMERALRPLFVNVTWGAGGS 59
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
TA +L++A+ Q +G+ T +HLTCTNM +D AL+ K G++N+LALRGDPP
Sbjct: 60 TAFKSLELAEICQRELGLTTCLHLTCTNMSRRLVDKALDDAKVLGIRNILALRGDPPRKA 119
Query: 439 DKFVQVE------GGFACARDLVK 492
+ V+ F A DLVK
Sbjct: 120 EYQDAVDEESDDGEDFVWATDLVK 143
[135][TOP]
>UniRef100_B6HK87 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6HK87_PENCW
Length = 691
Score = 112 bits (280), Expect = 1e-23
Identities = 67/145 (46%), Positives = 88/145 (60%), Gaps = 8/145 (5%)
Frame = +1
Query: 82 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGS 258
K+ EKI AA P+ FS EFFPPKT G NL R++RM A P F +TWGAGGS
Sbjct: 4 KITEKI---AALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS 60
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP--- 429
TA +L++A+ Q + + T++HLTCTNM + +D AL+ K G++N+LALRGDPP
Sbjct: 61 TAARSLELAEVCQRQLQLTTVLHLTCTNMSRKLVDMALDEAKVLGIRNILALRGDPPRSE 120
Query: 430 ----HGQDKFVQVEGGFACARDLVK 492
HG+D F A DLV+
Sbjct: 121 EYNMHGED---DSNKDFTFAVDLVR 142
[136][TOP]
>UniRef100_A1C4Z1 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C4Z1_ASPCL
Length = 690
Score = 112 bits (280), Expect = 1e-23
Identities = 68/145 (46%), Positives = 88/145 (60%), Gaps = 8/145 (5%)
Frame = +1
Query: 82 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGS 258
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPDANYFSLEFFPPKTKMGFANLQARLERMEQALRPLFVTVTWGAGGS 59
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP--- 429
TA +L++A+ Q + + T +HLTCTNM ID+ALE K G++N+LALRGDPP
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSE 119
Query: 430 ----HGQDKFVQVEGGFACARDLVK 492
HG+D F A DLV+
Sbjct: 120 EYNMHGED---DSNKDFTFAVDLVR 141
[137][TOP]
>UniRef100_UPI000023F2EE hypothetical protein FG07127.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023F2EE
Length = 672
Score = 112 bits (279), Expect = 2e-23
Identities = 58/120 (48%), Positives = 82/120 (68%), Gaps = 2/120 (1%)
Frame = +1
Query: 88 IEKIHEAAASDP-NKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGST 261
++KI + A+ P + FS EFFPPKT G NL +R+ RM A P F ++TWGAGGST
Sbjct: 1 MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST 60
Query: 262 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 441
+ +L++A+ Q VG+ T +HLTCTNM + ID+AL K+ G++N+LALRGDPP ++
Sbjct: 61 SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE 120
[138][TOP]
>UniRef100_Q7S2B6 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S2B6_NEUCR
Length = 681
Score = 112 bits (279), Expect = 2e-23
Identities = 58/120 (48%), Positives = 78/120 (65%), Gaps = 2/120 (1%)
Frame = +1
Query: 88 IEKIHE-AAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFXDITWGAGGST 261
+EKI + AA P+ FS EFFPPKT G NL +R++RM P F ++TWGAGGST
Sbjct: 1 MEKITDKVAALPPDSNYFSLEFFPPKTAMGFANLRDRLERMARGLRPLFVNVTWGAGGST 60
Query: 262 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 441
A +L++A+ Q +G+ T +HLTCTNM +D LE K G++N+LALRGDPP +
Sbjct: 61 AQKSLELAEICQRELGLTTCLHLTCTNMSRRLLDKTLEDAKVLGIRNILALRGDPPRAAE 120
[139][TOP]
>UniRef100_Q0CE17 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CE17_ASPTN
Length = 696
Score = 112 bits (279), Expect = 2e-23
Identities = 67/145 (46%), Positives = 87/145 (60%), Gaps = 8/145 (5%)
Frame = +1
Query: 82 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGS 258
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPDSNYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGS 59
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP--- 429
TA +L++A+ Q + + T +HLTCTNM +D ALE K G++N+LALRGDPP
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRGLVDKALEEAKVLGIRNILALRGDPPRSE 119
Query: 430 ----HGQDKFVQVEGGFACARDLVK 492
HG+D F A DLV+
Sbjct: 120 EYNMHGED---DSNKDFTFAVDLVR 141
[140][TOP]
>UniRef100_C1GJU2 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1GJU2_PARBD
Length = 712
Score = 111 bits (278), Expect = 2e-23
Identities = 62/141 (43%), Positives = 87/141 (61%), Gaps = 6/141 (4%)
Frame = +1
Query: 88 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGST 261
+E+I + A+ P FS EFFPPKT G +NL R++RM A P F ++TWGAGGST
Sbjct: 1 MERISDKIAALPQDANYFSLEFFPPKTPMGFLNLKARLERMSQALRPLFVNVTWGAGGST 60
Query: 262 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 441
+L++A+ Q +G+ T +HLTCTNM +DDAL + G++N+LALRGDPP ++
Sbjct: 61 VSKSLELAEMCQRQLGLTTCLHLTCTNMNRTLVDDALAEANALGIRNILALRGDPPRSEE 120
Query: 442 KFVQVEG----GFACARDLVK 492
+ E F A DLV+
Sbjct: 121 YNIDGEDDSNKDFTHAVDLVR 141
[141][TOP]
>UniRef100_Q04NW1 Methylenetetrahydrofolate reductase n=2 Tax=Leptospira
borgpetersenii serovar Hardjo-bovis RepID=Q04NW1_LEPBJ
Length = 290
Score = 111 bits (277), Expect = 3e-23
Identities = 55/137 (40%), Positives = 82/137 (59%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MK + +I+ +A V+SFEFFPPKT+DG + L+ + + P F +T+GAGGS
Sbjct: 1 MKKVSEIYGSAKGP----VYSFEFFPPKTQDGDLKLMGTVKELARLDPDFVTVTYGAGGS 56
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
T D T I ++ T+ H TC ++I L+ I+S+G+ N++ALRGDPP G+
Sbjct: 57 TRDKTAQILSEISKNYSFPTVSHFTCVGANQDQIFKTLKEIRSSGIVNLMALRGDPPKGE 116
Query: 439 DKFVQVEGGFACARDLV 489
KF + EGGF A +L+
Sbjct: 117 GKFKKTEGGFENATELI 133
[142][TOP]
>UniRef100_Q1DT03 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DT03_COCIM
Length = 711
Score = 110 bits (276), Expect = 4e-23
Identities = 64/141 (45%), Positives = 86/141 (60%), Gaps = 6/141 (4%)
Frame = +1
Query: 88 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGST 261
+EKI A+ P FS EFFPPKT+ G NL R++RM A P F +TWGAGG+T
Sbjct: 1 MEKISNKIAALPEDANYFSLEFFPPKTQMGSANLQARLERMSQALRPLFVTVTWGAGGTT 60
Query: 262 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 441
A +L++A+ Q +G+ T +HLTCTNM ID AL+ K+ G++N+LALRGDPP +
Sbjct: 61 ATKSLELAEICQRQLGLTTCLHLTCTNMNRTLIDSALDEAKALGIRNILALRGDPPRSDE 120
Query: 442 KFVQVEGG----FACARDLVK 492
+ E F A DLV+
Sbjct: 121 YNLDGEDDSNKEFTYAVDLVR 141
[143][TOP]
>UniRef100_C7YTQ6 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YTQ6_NECH7
Length = 674
Score = 110 bits (276), Expect = 4e-23
Identities = 62/126 (49%), Positives = 83/126 (65%), Gaps = 7/126 (5%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGV 312
FS EFFPPKT G NL +R+ RM A P F ++TWGAGGST+ +L++A+ Q +G+
Sbjct: 18 FSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGSTSQKSLELAELCQRELGL 77
Query: 313 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD----KFVQVEGG--FAC 474
T +HLTCTNM + ID ALE K+ G++N+LALRGDPP ++ + +GG F
Sbjct: 78 TTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRREEYRDPDDSEDDGGQDFNW 137
Query: 475 ARDLVK 492
A DLVK
Sbjct: 138 AADLVK 143
[144][TOP]
>UniRef100_C5P4Q4 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5P4Q4_COCP7
Length = 711
Score = 110 bits (276), Expect = 4e-23
Identities = 64/141 (45%), Positives = 86/141 (60%), Gaps = 6/141 (4%)
Frame = +1
Query: 88 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGST 261
+EKI A+ P FS EFFPPKT+ G NL R++RM A P F +TWGAGG+T
Sbjct: 1 MEKISNKIAALPEDADYFSLEFFPPKTQMGSANLQARLERMSQALRPLFVTVTWGAGGTT 60
Query: 262 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 441
A +L++A+ Q +G+ T +HLTCTNM ID AL+ K+ G++N+LALRGDPP +
Sbjct: 61 ATKSLELAEICQRQLGLTTCLHLTCTNMNRTLIDSALDEAKALGIRNILALRGDPPRSDE 120
Query: 442 KFVQVEGG----FACARDLVK 492
+ E F A DLV+
Sbjct: 121 YNLDGEDDSNKEFTYAVDLVR 141
[145][TOP]
>UniRef100_C1H0K0 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1H0K0_PARBA
Length = 713
Score = 110 bits (276), Expect = 4e-23
Identities = 62/141 (43%), Positives = 86/141 (60%), Gaps = 6/141 (4%)
Frame = +1
Query: 88 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGST 261
+E+I + A+ P FS EFFPPKT G +NL R++RM A P F +TWGAGGST
Sbjct: 1 MERISDKIAALPQDANYFSLEFFPPKTPMGFLNLKTRLERMSQALRPLFVTVTWGAGGST 60
Query: 262 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 441
+L++A+ Q +G+ T +HLTCTNM +DDAL + G++N+LALRGDPP ++
Sbjct: 61 VSKSLELAEMCQRQLGLTTCLHLTCTNMNRTLVDDALAEANALGIRNILALRGDPPRSEE 120
Query: 442 KFVQVEG----GFACARDLVK 492
+ E F A DLV+
Sbjct: 121 YNIDGEDDSNKDFTHAVDLVR 141
[146][TOP]
>UniRef100_B2WHR5 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WHR5_PYRTR
Length = 653
Score = 110 bits (276), Expect = 4e-23
Identities = 60/120 (50%), Positives = 79/120 (65%), Gaps = 2/120 (1%)
Frame = +1
Query: 88 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGST 261
+EKI + S P+ FS EFFPPKT G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKITDKINSLPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST 60
Query: 262 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 441
A +L++A+ Q +G+ T +HLTCTNM + IDDALE K G++N+LALRGD P ++
Sbjct: 61 ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDDALEQAKVLGIRNILALRGDAPRSEE 120
[147][TOP]
>UniRef100_A4IC95 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania infantum
RepID=A4IC95_LEIIN
Length = 309
Score = 110 bits (275), Expect = 5e-23
Identities = 56/130 (43%), Positives = 85/130 (65%), Gaps = 2/130 (1%)
Frame = +1
Query: 109 AASDPNKVVFSFEFFPPKTEDGVVNLLERM-DRMVAHSPSFXDITWGAGGSTADVTLDIA 285
AA D +K S+E +PP++E ++++ + + SP F D+TWGAGG T+D T+ +
Sbjct: 10 AAEDVSKWYTSYELYPPRSEKAEEDMMKVLVPNFMRQSPVFLDLTWGAGGRTSDTTMRLC 69
Query: 286 KKMQNTV-GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEG 462
K +Q+ MH+TCTN P I++AL+ K++G++N+LALRGDPP G++ F
Sbjct: 70 KDLQHAYPDTPINMHITCTNTPKGLINEALDFAKTHGIRNILALRGDPPRGEE-FRADPD 128
Query: 463 GFACARDLVK 492
GFACARDLV+
Sbjct: 129 GFACARDLVR 138
[148][TOP]
>UniRef100_C0S8C4 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0S8C4_PARBP
Length = 712
Score = 110 bits (274), Expect = 6e-23
Identities = 62/141 (43%), Positives = 86/141 (60%), Gaps = 6/141 (4%)
Frame = +1
Query: 88 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGST 261
+E+I + A+ P FS EFFPPKT G +NL R++RM A P F +TWGAGGST
Sbjct: 1 MERISDKIAALPQDANYFSLEFFPPKTPMGFLNLKARLERMSQALRPLFVTVTWGAGGST 60
Query: 262 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 441
+L++A+ Q +G+ T +HLTCTNM +DDAL + G++N+LALRGDPP ++
Sbjct: 61 VSKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDDALAEANALGIRNILALRGDPPRSEE 120
Query: 442 KFVQVEG----GFACARDLVK 492
+ E F A DLV+
Sbjct: 121 YNIDGEDDSNKDFTHAVDLVR 141
[149][TOP]
>UniRef100_B2B6X0 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B6X0_PODAN
Length = 691
Score = 109 bits (272), Expect = 1e-22
Identities = 58/120 (48%), Positives = 80/120 (66%), Gaps = 2/120 (1%)
Frame = +1
Query: 76 KMKVIEKIHEAAASDPNKVVF-SFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGA 249
K ++KI + A+ P + + S EFFPPKT G NL +R+DRM A P F ++TWGA
Sbjct: 16 KNHAMDKITDKIAALPAETNYCSLEFFPPKTAMGFSNLRDRLDRMARALRPLFVNVTWGA 75
Query: 250 GGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 429
GGSTA +L++A+ Q + + T +HLTCTNM + ID LE K+ G++N+LALRGDPP
Sbjct: 76 GGSTATKSLELAEICQRELSLTTCLHLTCTNMSRKLIDKTLEDAKALGIRNILALRGDPP 135
[150][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 108 bits (271), Expect = 1e-22
Identities = 51/104 (49%), Positives = 77/104 (74%), Gaps = 3/104 (2%)
Frame = +1
Query: 139 SFEFFPPKTEDGVVNLLERMDRMVA---HSPSFXDITWGAGGSTADVTLDIAKKMQNTVG 309
++EFFPP T+ G VNLL+R+ R+ + +P +TWGAGGSTA+ +L++A+++ + +G
Sbjct: 17 NYEFFPPLTDPGFVNLLDRIRRLTSSPFQAPLAVSVTWGAGGSTAEKSLELAQQVVD-MG 75
Query: 310 VETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 441
VE ++HLTCTNMP +K+D AL K G+ N+LALRGDPP ++
Sbjct: 76 VEVILHLTCTNMPKDKVDFALRRCKDLGISNILALRGDPPREEE 119
[151][TOP]
>UniRef100_C5DIA7 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5DIA7_LACTC
Length = 660
Score = 108 bits (270), Expect = 2e-22
Identities = 60/119 (50%), Positives = 74/119 (62%), Gaps = 1/119 (0%)
Frame = +1
Query: 139 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVET 318
S EFFPPKT+ G NL RM RM A +P F ITWGAGG+TA TL++A Q + V
Sbjct: 36 SLEFFPPKTKLGKQNLTARMTRMTALNPLFITITWGAGGTTAKKTLELATVAQRELNVPV 95
Query: 319 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG-FACARDLVK 492
MHLTCTN E ID+AL+ ++N+LALRGDPP G++ E F A DLV+
Sbjct: 96 CMHLTCTNTNKEIIDEALKLAHEADIRNILALRGDPPVGEEWETPSESSEFQHAVDLVR 154
[152][TOP]
>UniRef100_Q8EY55 Methylenetetrahydrofolate reductase n=1 Tax=Leptospira interrogans
RepID=Q8EY55_LEPIN
Length = 310
Score = 108 bits (269), Expect = 2e-22
Identities = 55/137 (40%), Positives = 83/137 (60%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MK + +I+ +A V+SFEFFPPKT +G L+E + + +P F +T+GAGGS
Sbjct: 18 MKKVSEIYGSAKGP----VYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGS 73
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
T D T+ I ++ T+ H TC +I + L+ I+S+G+ N++ALRGDPP G+
Sbjct: 74 TRDKTVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGE 133
Query: 439 DKFVQVEGGFACARDLV 489
+F +VE GF A +LV
Sbjct: 134 GEFKKVENGFGNATELV 150
[153][TOP]
>UniRef100_Q75G11 Methylenetetrahydrofolate reductase n=2 Tax=Leptospira interrogans
RepID=Q75G11_LEPIC
Length = 310
Score = 108 bits (269), Expect = 2e-22
Identities = 55/137 (40%), Positives = 83/137 (60%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MK + +I+ +A V+SFEFFPPKT +G L+E + + +P F +T+GAGGS
Sbjct: 18 MKKVSEIYGSAKGP----VYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGS 73
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
T D T+ I ++ T+ H TC +I + L+ I+S+G+ N++ALRGDPP G+
Sbjct: 74 TRDKTVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGE 133
Query: 439 DKFVQVEGGFACARDLV 489
+F +VE GF A +LV
Sbjct: 134 GEFKKVENGFGNATELV 150
[154][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 108 bits (269), Expect = 2e-22
Identities = 61/124 (49%), Positives = 78/124 (62%), Gaps = 5/124 (4%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFXDITWGAGGSTADVTLDIAKKMQNTVGV 312
+SFEFFPPKTE G+ NLL R+DRM P F ITWG+ GST TL +A Q V
Sbjct: 1 YSFEFFPPKTEPGLDNLLTRIDRMCRRLDPLFVSITWGSNGSTLSRTLAVASHAQRFACV 60
Query: 313 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQ--VEGGFACAR-- 480
+ ++HL+CT + E+I L KS+G+ N+LALRGDPP G+ + + V GG C R
Sbjct: 61 DVLLHLSCTGLTREQIGHVLAMAKSSGVHNILALRGDPPQGKRAWKEGDVSGG-ECDRAI 119
Query: 481 DLVK 492
DLVK
Sbjct: 120 DLVK 123
[155][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR2_SCHPO
Length = 641
Score = 107 bits (267), Expect = 4e-22
Identities = 60/140 (42%), Positives = 84/140 (60%), Gaps = 2/140 (1%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPN-KVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFXDITWGAG 252
MK+++ I + PN +SFE+FPPKT G+ NL R+ RM + P F +TWG
Sbjct: 1 MKIVDLIDKI----PNGNAFYSFEYFPPKTTVGLENLSSRITRMSRNMMPLFSSVTWGTA 56
Query: 253 GSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 432
GSTA+V++ +AK ++ + +HLTCTN+ ID ALET K G++N+LALRGDPP
Sbjct: 57 GSTAEVSIYLAKMLEQHHKIPACLHLTCTNVDKAIIDKALETAKEYGIRNILALRGDPPL 116
Query: 433 GQDKFVQVEGGFACARDLVK 492
D + F A DLV+
Sbjct: 117 NSDHWEGKVSEFEHAVDLVR 136
[156][TOP]
>UniRef100_Q1D7X5 Methylenetetrahydrofolate reductase n=1 Tax=Myxococcus xanthus DK
1622 RepID=Q1D7X5_MYXXD
Length = 290
Score = 107 bits (266), Expect = 5e-22
Identities = 50/125 (40%), Positives = 75/125 (60%)
Frame = +1
Query: 118 DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQ 297
+P+ FSFEFFPP+T++G NLL+ ++ + P F +T GAGGST T+++ +++
Sbjct: 8 NPSDPCFSFEFFPPRTDEGEANLLKALEDLATLQPGFVSVTEGAGGSTRAKTVELVLRIK 67
Query: 298 NTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACA 477
G+E M HLTC ++ LE + + + NVL LRGDPP GQ F GGF A
Sbjct: 68 QEAGIEAMAHLTCGGHSPAELRTVLERLSAAKVDNVLVLRGDPPKGQTVFEPAPGGFRYA 127
Query: 478 RDLVK 492
++V+
Sbjct: 128 SEMVR 132
[157][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 106 bits (265), Expect = 7e-22
Identities = 61/123 (49%), Positives = 78/123 (63%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T G VNL+ R DRM + P F DITW G GS + ++ IA N
Sbjct: 60 FSLEFFPPRTSSGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY 119
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+E+++HLTC N EKI D L K GL+N++ALRGDP G+D +V+ +GGF A D
Sbjct: 120 CGLESVLHLTCCNQTKEKITDHLNKAKRLGLKNIMALRGDPV-GED-WVEEDGGFNFATD 177
Query: 484 LVK 492
LVK
Sbjct: 178 LVK 180
[158][TOP]
>UniRef100_B7GB47 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B7GB47_PHATR
Length = 376
Score = 105 bits (263), Expect = 1e-21
Identities = 61/150 (40%), Positives = 82/150 (54%), Gaps = 28/150 (18%)
Frame = +1
Query: 127 KVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGSTADVTLDIAKKMQNT 303
K S E+FPP+T +GV NL RM RM P+F D+TWGAGGSTA+++L +A NT
Sbjct: 39 KPFVSLEYFPPRTAEGVQNLHARMHRMRDTLQPAFTDMTWGAGGSTAELSLQLALYAHNT 98
Query: 304 VGVETMMHLTCTNM---------------------------PVEKIDDALETIKSNGLQN 402
G +H+TCTN+ P E + AL+ G++N
Sbjct: 99 -GHVANLHMTCTNLDSGKSSTSTSSSSEHNGNASDDVASADPRETLRRALQQAHDGGIRN 157
Query: 403 VLALRGDPPHGQDKFVQVEGGFACARDLVK 492
++ALRGDPP GQ+ + EGGF CA DLV+
Sbjct: 158 LVALRGDPPAGQETWTATEGGFTCALDLVE 187
[159][TOP]
>UniRef100_Q4Q0B9 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania major
RepID=Q4Q0B9_LEIMA
Length = 309
Score = 105 bits (263), Expect = 1e-21
Identities = 56/130 (43%), Positives = 83/130 (63%), Gaps = 2/130 (1%)
Frame = +1
Query: 109 AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFXDITWGAGGSTADVTLDIA 285
AA D +K S+E +PP++E ++++ + H SP F D+TWGAGG T+ T+ +
Sbjct: 10 AAEDASKWNTSYELYPPRSEKAEEDMMKVLVPNFMHQSPVFLDLTWGAGGRTSGTTMRLC 69
Query: 286 KKMQNT-VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEG 462
K +Q+ MH+TCTN P I + LE K++G++N+LALRGDPP G++ V +
Sbjct: 70 KDLQHAHPDTPINMHITCTNTPKGLIKETLEFAKTHGIRNILALRGDPPSGEEFQVDPD- 128
Query: 463 GFACARDLVK 492
GFACARDLV+
Sbjct: 129 GFACARDLVR 138
[160][TOP]
>UniRef100_A5KL25 Methylenetetrahydrofolate reductase n=1 Tax=Ruminococcus torques
ATCC 27756 RepID=A5KL25_9FIRM
Length = 289
Score = 104 bits (259), Expect = 4e-21
Identities = 48/119 (40%), Positives = 77/119 (64%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MK+I+++ E +K+ SFE FPPKT+ G ++ D M +P+F +T+GAGG
Sbjct: 1 MKIIDRLKE------DKIHISFEVFPPKTDAGFEKVIAATDAMAKLNPAFISVTYGAGGG 54
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 435
T+ T IA +++ +GV ++ HLTC + +E++ D +E +K NG++N+LALRGD P G
Sbjct: 55 TSKNTAKIASHIKDDLGVVSLAHLTCASSTIEEVRDVIENLKENGIENILALRGDIPEG 113
[161][TOP]
>UniRef100_C1XL88 Methylenetetrahydrofolate reductase n=1 Tax=Meiothermus ruber DSM
1279 RepID=C1XL88_MEIRU
Length = 291
Score = 103 bits (257), Expect = 6e-21
Identities = 53/121 (43%), Positives = 71/121 (58%)
Frame = +1
Query: 127 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTV 306
K +FSFEFFPPKT G L + + P+F IT+GAGGS + T + A ++QN V
Sbjct: 11 KPLFSFEFFPPKTPRGEAALFRTLHELKPLKPAFVSITYGAGGSERNKTAEWAARIQNEV 70
Query: 307 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDL 486
G+ M HLTC E++ L G++N++ALRGDPP G +F V GGF A +L
Sbjct: 71 GLPAMAHLTCVGSTREELLARLHEYARAGVENIMALRGDPPQGAREFQPVAGGFRYAAEL 130
Query: 487 V 489
V
Sbjct: 131 V 131
[162][TOP]
>UniRef100_A3DBL1 Methylenetetrahydrofolate reductase n=3 Tax=Clostridium
thermocellum RepID=A3DBL1_CLOTH
Length = 291
Score = 103 bits (257), Expect = 6e-21
Identities = 49/121 (40%), Positives = 73/121 (60%)
Frame = +1
Query: 127 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTV 306
K V SFE FPPK + + ++ +++ P F +T+GAGGS D T++IA K++N
Sbjct: 11 KPVISFEIFPPKLDTPIESIFGTLEQFKELKPDFISVTYGAGGSAKDRTIEIASKIKNEY 70
Query: 307 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDL 486
G+E+M HLTC E+ID L +++ + L+N+LALRGDPP Q F F A +L
Sbjct: 71 GIESMAHLTCVGHSKEEIDALLTSMREHNLENILALRGDPPANQPDFDFSNNAFKYANEL 130
Query: 487 V 489
+
Sbjct: 131 I 131
[163][TOP]
>UniRef100_C8X270 5,10-methylenetetrahydrofolate reductase n=1 Tax=Desulfohalobium
retbaense DSM 5692 RepID=C8X270_9DELT
Length = 293
Score = 103 bits (256), Expect = 8e-21
Identities = 51/124 (41%), Positives = 72/124 (58%)
Frame = +1
Query: 121 PNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQN 300
P K S EFFPPK E E + ++ + P F +T+GAGGST D TL + +++
Sbjct: 9 PGKKFISLEFFPPKDEGNWPGFFEEVHQLASMDPLFVSVTYGAGGSTQDNTLRLVSRLKQ 68
Query: 301 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACAR 480
+G+E M HLTC + D + +++++ + NVLALRGDPP GQD FV F A
Sbjct: 69 -MGLEPMAHLTCVGASAATLHDFMRSLQASDIDNVLALRGDPPQGQDTFVPDNADFQHAS 127
Query: 481 DLVK 492
DLV+
Sbjct: 128 DLVR 131
[164][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 102 bits (254), Expect = 1e-20
Identities = 57/123 (46%), Positives = 74/123 (60%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 65 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTALNY 124
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC E+I L K GL+N++ALRGDP D + EGGF+ A D
Sbjct: 125 CGLETILHMTCCQQRQEEISGHLHRAKQLGLKNIMALRGDPV--GDHWEAEEGGFSYATD 182
Query: 484 LVK 492
LVK
Sbjct: 183 LVK 185
[165][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 102 bits (254), Expect = 1e-20
Identities = 57/123 (46%), Positives = 74/123 (60%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTALNY 159
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC E+I L K GL+N++ALRGDP D + EGGF+ A D
Sbjct: 160 CGLETILHMTCCQQRQEEISGHLHRAKQLGLKNIMALRGDPV--GDHWEAEEGGFSYATD 217
Query: 484 LVK 492
LVK
Sbjct: 218 LVK 220
[166][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 102 bits (253), Expect = 2e-20
Identities = 57/123 (46%), Positives = 74/123 (60%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 159
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC E+I L K GL+N++ALRGDP D + EGGF+ A D
Sbjct: 160 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDPV--GDHWEAEEGGFSYATD 217
Query: 484 LVK 492
LVK
Sbjct: 218 LVK 220
[167][TOP]
>UniRef100_B2KFL5 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Mus musculus
RepID=B2KFL5_MOUSE
Length = 194
Score = 102 bits (253), Expect = 2e-20
Identities = 57/123 (46%), Positives = 74/123 (60%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC E+I L K GL+N++ALRGDP D + EGGF+ A D
Sbjct: 119 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDPV--GDHWEAEEGGFSYATD 176
Query: 484 LVK 492
LVK
Sbjct: 177 LVK 179
[168][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 102 bits (253), Expect = 2e-20
Identities = 57/123 (46%), Positives = 74/123 (60%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 159
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC E+I L K GL+N++ALRGDP D + EGGF+ A D
Sbjct: 160 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDPV--GDHWEAEEGGFSYATD 217
Query: 484 LVK 492
LVK
Sbjct: 218 LVK 220
[169][TOP]
>UniRef100_A2A7F9 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Mus musculus
RepID=A2A7F9_MOUSE
Length = 194
Score = 102 bits (253), Expect = 2e-20
Identities = 57/123 (46%), Positives = 74/123 (60%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC E+I L K GL+N++ALRGDP D + EGGF+ A D
Sbjct: 119 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDPV--GDHWEAEEGGFSYATD 176
Query: 484 LVK 492
LVK
Sbjct: 177 LVK 179
[170][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 102 bits (253), Expect = 2e-20
Identities = 57/123 (46%), Positives = 74/123 (60%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 159
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC E+I L K GL+N++ALRGDP D + EGGF+ A D
Sbjct: 160 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDPV--GDHWEAEEGGFSYATD 217
Query: 484 LVK 492
LVK
Sbjct: 218 LVK 220
[171][TOP]
>UniRef100_B6FS52 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium nexile DSM
1787 RepID=B6FS52_9CLOT
Length = 288
Score = 102 bits (253), Expect = 2e-20
Identities = 50/117 (42%), Positives = 74/117 (63%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MK+ +++ E N+V SFE FPPKT+ G +LE + + A PSF +T+GAGG
Sbjct: 1 MKIKDRLSE------NRVNISFEVFPPKTDAGYGKVLEATEEIAALKPSFISVTYGAGGG 54
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 429
T+ T+ IA +QN +GV ++ HLTC + E++ +E +K G+QN+LALRGD P
Sbjct: 55 TSKNTVKIASHIQNDLGVASLAHLTCASSTKEEVRQVIEQLKEQGIQNILALRGDIP 111
[172][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 102 bits (253), Expect = 2e-20
Identities = 57/123 (46%), Positives = 74/123 (60%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC E+I L K GL+N++ALRGDP D + EGGF+ A D
Sbjct: 119 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDPV--GDHWEAEEGGFSYATD 176
Query: 484 LVK 492
LVK
Sbjct: 177 LVK 179
[173][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 101 bits (252), Expect = 2e-20
Identities = 53/122 (43%), Positives = 72/122 (59%), Gaps = 4/122 (3%)
Frame = +1
Query: 85 VIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTA 264
+IEKIH+ K FS EFFPP+T +G VNL+ R DRM P F DITW G +
Sbjct: 21 LIEKIHKHIGK--KKKFFSLEFFPPRTPNGAVNLVARFDRMSQGGPLFCDITWHPAGDPS 78
Query: 265 D----VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 432
+ IA N G+ETM+H+TC N+ + + L+ K+ G++N+LALRGDPP
Sbjct: 79 GDKETSSCTIASTASNYCGIETMLHMTCANISCDLVLKNLKKAKNLGIRNILALRGDPPK 138
Query: 433 GQ 438
G+
Sbjct: 139 GE 140
[174][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 101 bits (252), Expect = 2e-20
Identities = 56/123 (45%), Positives = 76/123 (61%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T +G VNL+ R DRM A P + D+TW G GS + ++ IA N
Sbjct: 83 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNY 142
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC +E+I L K GL+N++ALRGDP D++ + EGGF A D
Sbjct: 143 CGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPI--GDQWEEEEGGFNYAVD 200
Query: 484 LVK 492
LVK
Sbjct: 201 LVK 203
[175][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 101 bits (252), Expect = 2e-20
Identities = 56/123 (45%), Positives = 76/123 (61%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T +G VNL+ R DRM A P + D+TW G GS + ++ IA N
Sbjct: 101 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNY 160
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC +E+I L K GL+N++ALRGDP D++ + EGGF A D
Sbjct: 161 CGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPI--GDQWEEEEGGFNYAVD 218
Query: 484 LVK 492
LVK
Sbjct: 219 LVK 221
[176][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 101 bits (252), Expect = 2e-20
Identities = 57/123 (46%), Positives = 76/123 (61%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 83 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 142
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC +E+I L K GL+N++ALRGDP D++ + EGGF A D
Sbjct: 143 CGLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDPI--GDQWEEEEGGFNYAVD 200
Query: 484 LVK 492
LVK
Sbjct: 201 LVK 203
[177][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 101 bits (252), Expect = 2e-20
Identities = 57/123 (46%), Positives = 76/123 (61%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 101 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 160
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC +E+I L K GL+N++ALRGDP D++ + EGGF A D
Sbjct: 161 CGLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDPI--GDQWEEEEGGFNYAVD 218
Query: 484 LVK 492
LVK
Sbjct: 219 LVK 221
[178][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 101 bits (252), Expect = 2e-20
Identities = 58/123 (47%), Positives = 75/123 (60%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNY 118
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC + E+I L K GL+N+LALRGDP D++ + EGGF A D
Sbjct: 119 CGLETILHMTCCHQSREEITGHLNKAKQLGLKNILALRGDPI--GDQWEEEEGGFNYATD 176
Query: 484 LVK 492
LVK
Sbjct: 177 LVK 179
[179][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 101 bits (252), Expect = 2e-20
Identities = 56/123 (45%), Positives = 76/123 (61%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T +G VNL+ R DRM A P + D+TW G GS + ++ IA N
Sbjct: 60 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNY 119
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC +E+I L K GL+N++ALRGDP D++ + EGGF A D
Sbjct: 120 CGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPI--GDQWEEEEGGFNYAVD 177
Query: 484 LVK 492
LVK
Sbjct: 178 LVK 180
[180][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 101 bits (252), Expect = 2e-20
Identities = 56/123 (45%), Positives = 76/123 (61%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T +G VNL+ R DRM A P + D+TW G GS + ++ IA N
Sbjct: 90 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNY 149
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC +E+I L K GL+N++ALRGDP D++ + EGGF A D
Sbjct: 150 CGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPI--GDQWEEEEGGFNYAVD 207
Query: 484 LVK 492
LVK
Sbjct: 208 LVK 210
[181][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 101 bits (252), Expect = 2e-20
Identities = 57/123 (46%), Positives = 76/123 (61%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 60 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 119
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC +E+I L K GL+N++ALRGDP D++ + EGGF A D
Sbjct: 120 CGLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDPI--GDQWEEEEGGFNYAVD 177
Query: 484 LVK 492
LVK
Sbjct: 178 LVK 180
[182][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 101 bits (252), Expect = 2e-20
Identities = 58/123 (47%), Positives = 75/123 (60%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNY 118
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC + E+I L K GL+N+LALRGDP D++ + EGGF A D
Sbjct: 119 CGLETILHMTCCHQSREEITGHLNKAKQLGLKNILALRGDPI--GDQWEEEEGGFNYATD 176
Query: 484 LVK 492
LVK
Sbjct: 177 LVK 179
[183][TOP]
>UniRef100_A6G2Q2 Methylenetetrahydrofolate reductase n=1 Tax=Plesiocystis pacifica
SIR-1 RepID=A6G2Q2_9DELT
Length = 310
Score = 101 bits (251), Expect = 3e-20
Identities = 47/118 (39%), Positives = 73/118 (61%)
Frame = +1
Query: 133 VFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGV 312
VFSFEFFPPK E G L ++++ P F +T+GAGGST + T+++ +++ +G+
Sbjct: 13 VFSFEFFPPKHEKGERVLWRSLEQLRTLEPDFVSVTYGAGGSTRERTVELVARIKTELGI 72
Query: 313 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDL 486
E M HLTC +++ +E + + + N+LALRGDPP G+ +F GGF A +L
Sbjct: 73 EPMAHLTCVGSTRDELARVVERLLAADVHNILALRGDPPKGETEFQHTPGGFRYASEL 130
[184][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 101 bits (251), Expect = 3e-20
Identities = 56/140 (40%), Positives = 77/140 (55%), Gaps = 4/140 (2%)
Frame = +1
Query: 85 VIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW----GAG 252
+I+KI + S +S EFFPP+T+ G VNL+ R DR+ +P F D+TW +G
Sbjct: 26 IIQKIRKRINSGDK--FYSLEFFPPRTDSGGVNLIARFDRLAIGNPLFIDVTWHPKGNSG 83
Query: 253 GSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 432
G +L IA N G+++M+H+TC N E ID L K GL+N+LALRGD
Sbjct: 84 GDEVTASLTIASAALNFCGLDSMLHMTCINSTTEDIDKYLRKAKKQGLRNILALRGDVSD 143
Query: 433 GQDKFVQVEGGFACARDLVK 492
D+ V+ A DLVK
Sbjct: 144 SIDESVRHTKELKYASDLVK 163
[185][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 100 bits (250), Expect = 4e-20
Identities = 57/123 (46%), Positives = 75/123 (60%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T G VNL+ R D+M A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAQGAVNLISRFDQMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC E+I L K GL+N+LALRGDP D++ + EGGF+ A D
Sbjct: 119 CGLETVLHMTCCRQSREEITGYLHKAKRLGLKNILALRGDPV--GDQWEEEEGGFSYAAD 176
Query: 484 LVK 492
LVK
Sbjct: 177 LVK 179
[186][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 100 bits (250), Expect = 4e-20
Identities = 50/109 (45%), Positives = 72/109 (66%), Gaps = 2/109 (1%)
Frame = +1
Query: 172 GVVNLLERMDRMVAHSPSFXDITWGAGG--STADVTLDIAKKMQNTVGVETMMHLTCTNM 345
GV NL ER+DRM P + D+TWGAGG S+++ T +I + G++ MMHLTCT+
Sbjct: 2 GVQNLYERLDRMAELGPMWIDVTWGAGGASSSSNKTFEICRNALTYHGLDVMMHLTCTHQ 61
Query: 346 PVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
VE+ID+ L+ K G++N+LALRGD P ++ +GGF+ A DLV+
Sbjct: 62 SVEEIDEVLDKCKEVGIRNILALRGDAPTQSSEWRACQGGFSHAVDLVR 110
[187][TOP]
>UniRef100_B4S8Y1 Methylenetetrahydrofolate reductase n=1 Tax=Prosthecochloris
aestuarii DSM 271 RepID=B4S8Y1_PROA2
Length = 296
Score = 100 bits (249), Expect = 5e-20
Identities = 50/126 (39%), Positives = 72/126 (57%)
Frame = +1
Query: 115 SDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKM 294
S + +FSFEFFPPK D L + ++ +PS+ +T+GAGGST T D+ K+
Sbjct: 8 SSTDNPIFSFEFFPPKKNDDWDRLFRTISELIPFNPSYVSVTYGAGGSTRTRTHDLVTKI 67
Query: 295 QNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFAC 474
+ G+ + HLTC ++I D L T ++NG+ NVLALRGD P G + + F
Sbjct: 68 RKETGLTVVSHLTCICSTKDEISDILSTYENNGITNVLALRGDLPPGTTSYSEATKDFPH 127
Query: 475 ARDLVK 492
A DLV+
Sbjct: 128 AIDLVR 133
[188][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 100 bits (249), Expect = 5e-20
Identities = 50/109 (45%), Positives = 71/109 (65%), Gaps = 2/109 (1%)
Frame = +1
Query: 172 GVVNLLERMDRMVAHSPSFXDITWGAGGSTA--DVTLDIAKKMQNTVGVETMMHLTCTNM 345
GV NL ER+DRM P + D+TWGAGGS++ + T +I + G++ MMHLTCT
Sbjct: 2 GVQNLYERLDRMAELGPMWIDVTWGAGGSSSSSNKTFEICRNALTYHGLDVMMHLTCTQQ 61
Query: 346 PVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
VE+ID+ L+ K G++N+LALRGD P ++ +GGF+ A DLV+
Sbjct: 62 SVEEIDEVLDKCKEVGIRNILALRGDAPTQSSEWRACQGGFSHAVDLVR 110
[189][TOP]
>UniRef100_A8UU31 Methylenetetrahydrofolate reductase n=1 Tax=Hydrogenivirga sp.
128-5-R1-1 RepID=A8UU31_9AQUI
Length = 298
Score = 100 bits (248), Expect = 7e-20
Identities = 49/118 (41%), Positives = 72/118 (61%)
Frame = +1
Query: 139 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVET 318
SFEFFPPK E+G L + + + P+F +T+GAGGST D T ++ K++ VG+
Sbjct: 15 SFEFFPPKGEEGERQLFQTIKELEELKPTFVSVTYGAGGSTRDRTRNVVKRIHEEVGLTV 74
Query: 319 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
M HLTC E++ + LE + G++N+LALRGD PH F EG + A++LV+
Sbjct: 75 MAHLTCIAHTREELIEILEDYRGIGIENILALRGDVPHDTPDFRPPEGACSYAKELVE 132
[190][TOP]
>UniRef100_B3QV58 Methylenetetrahydrofolate reductase n=1 Tax=Chloroherpeton
thalassium ATCC 35110 RepID=B3QV58_CHLT3
Length = 294
Score = 99.8 bits (247), Expect = 9e-20
Identities = 47/123 (38%), Positives = 70/123 (56%)
Frame = +1
Query: 121 PNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQN 300
P+K FSFEF+PPK ++ L + ++ +P++ +T+GAGGST D T ++ ++
Sbjct: 9 PDKTQFSFEFYPPKKDEEWEKLFFHISELMPMNPAYVSVTYGAGGSTRDKTHNLVVRISK 68
Query: 301 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACAR 480
+ + HLTC +I LE NG+ N+LALRGDPP G F + GFA A
Sbjct: 69 ETNIPVVSHLTCVGSSKSEIHTILERYAENGITNILALRGDPPKGSTTFEKPADGFAYAN 128
Query: 481 DLV 489
+LV
Sbjct: 129 ELV 131
[191][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 99.8 bits (247), Expect = 9e-20
Identities = 59/143 (41%), Positives = 81/143 (56%), Gaps = 5/143 (3%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
+K+ ++I A D + FS EFFPP+T G NL+ R +RMV P F DITW G
Sbjct: 30 VKLADRIE--AKIDRGERWFSLEFFPPRTPQGAANLISRFERMVQGGPMFMDITWHPAGD 87
Query: 259 TAD-----VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGD 423
+ ++ IA N VG ETM+H++C N + I L+ K G++N+LALRGD
Sbjct: 88 PGNSDKETSSMSIACAALNYVGHETMLHMSCCNSTKDDIRRHLDKAKELGIRNILALRGD 147
Query: 424 PPHGQDKFVQVEGGFACARDLVK 492
P G D++ VE GF A D+VK
Sbjct: 148 PIVG-DEWKYVEDGFNYATDMVK 169
[192][TOP]
>UniRef100_UPI000196BD8E hypothetical protein CATMIT_02257 n=1 Tax=Catenibacterium mitsuokai
DSM 15897 RepID=UPI000196BD8E
Length = 287
Score = 99.4 bits (246), Expect = 1e-19
Identities = 51/132 (38%), Positives = 80/132 (60%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MK+I+ ++E +KV SFE FPPKT N+L+ +++ + +P+F +T+GAGG
Sbjct: 1 MKIIDLLNE------DKVTLSFEVFPPKTSGRYENVLKAAEKIASLNPNFMSVTYGAGGG 54
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
T+ T+ +AK + GVE M HLTC + E ++ +E K NG++N++ALRGD P
Sbjct: 55 TSAHTVALAKDIHEKYGVEVMAHLTCVSSTKEHVESMVEQFKENGIENIMALRGDIP--S 112
Query: 439 DKFVQVEGGFAC 474
D V + +AC
Sbjct: 113 DGKVGEDYQYAC 124
[193][TOP]
>UniRef100_A1VEZ2 Methylenetetrahydrofolate reductase n=3 Tax=Desulfovibrio vulgaris
RepID=A1VEZ2_DESVV
Length = 291
Score = 99.0 bits (245), Expect = 1e-19
Identities = 55/138 (39%), Positives = 76/138 (55%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MK+ E I + + +S EFFPPK + ++R+ A P F +T+GAGG
Sbjct: 1 MKIAEAIERQS-----RPFYSLEFFPPKEREQWPAFFATVERLKAMDPVFASVTYGAGGG 55
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
T D TLDI ++N +G+E M HLTC E+I L ++ G++NVLALRGDPP GQ
Sbjct: 56 TQDNTLDITAHLKNALGLEPMAHLTCVGATRERIAGFLARLREQGVENVLALRGDPPRGQ 115
Query: 439 DKFVQVEGGFACARDLVK 492
+ F A DLV+
Sbjct: 116 QVDWET-AEFRYASDLVR 132
[194][TOP]
>UniRef100_B0N2P6 Methylenetetrahydrofolate reductase n=2 Tax=Bacteria
RepID=B0N2P6_9FIRM
Length = 296
Score = 99.0 bits (245), Expect = 1e-19
Identities = 47/122 (38%), Positives = 76/122 (62%), Gaps = 1/122 (0%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDG-VVNLLERMDRMVAHSPSFXDITWGAGG 255
MK+I+ +H + SFE FPPK DG + ++ + +D + P F +T+GAGG
Sbjct: 1 MKIIDLLHR-------RPTLSFEIFPPKNHDGDISSIYQTIDELAKLKPDFISVTYGAGG 53
Query: 256 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 435
ST + T++IA K++N +E + HL+C + E++ L+++K+N ++NVLALRGD P G
Sbjct: 54 STTENTVEIASKIKNEYSIEAVAHLSCIDATPEQLIRVLDSLKANNIENVLALRGDYPRG 113
Query: 436 QD 441
D
Sbjct: 114 YD 115
[195][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 98.6 bits (244), Expect = 2e-19
Identities = 59/123 (47%), Positives = 75/123 (60%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T G VNL+ R DRM + P F DITW G GS + ++ IA N
Sbjct: 64 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY 123
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+E+++HLTC N +KI L K GL+N++ALRGDP G D + + EGGF A D
Sbjct: 124 CGLESILHLTCCNQTKDKITGYLGKAKHLGLKNIMALRGDPV-GAD-WEEEEGGFNYAVD 181
Query: 484 LVK 492
LVK
Sbjct: 182 LVK 184
[196][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 98.6 bits (244), Expect = 2e-19
Identities = 50/123 (40%), Positives = 72/123 (58%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTAD----VTLDIAKKMQNT 303
FS EFFPP+T +G VNLL DR+ + P F D+TW G + ++ IA N
Sbjct: 12 FSVEFFPPRTPNGAVNLLGTFDRLASACPLFCDVTWHPAGDPSGDKDTSSMTIASTALNY 71
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ETM+H+TC N + L K+ G++N+LALRGDPP G++ + +E G A D
Sbjct: 72 CGLETMLHMTCANQTKASVTKNLHKAKTLGIRNILALRGDPPDGEE-WKALEDGLAYGAD 130
Query: 484 LVK 492
+V+
Sbjct: 131 MVR 133
[197][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 98.6 bits (244), Expect = 2e-19
Identities = 67/199 (33%), Positives = 97/199 (48%), Gaps = 41/199 (20%)
Frame = +1
Query: 19 LSSPPYPLSLSL--ASIKD*NKMKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLE 192
++S LS SL A+ + + KI A D +SFEFFPPKT G+ NL
Sbjct: 1 MASDSAALSASLHGATASPSDPAHIATKIQAALTRDAP--FWSFEFFPPKTSQGLANLYN 58
Query: 193 RMDRM-VAHSPSFXDITWGAGGSTADVTLDIAKKMQ---------------NTVGVETM- 321
R+ RM V PS+ +TWGAGG+T +L++A ++Q N +G T
Sbjct: 59 RIARMHVNLEPSWIHVTWGAGGTTGGKSLELAGRIQKGKLDPDVELVQTEINHIGSGTQQ 118
Query: 322 ----------------------MHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 435
+HLTCTN+ +D L+T K G++N+LALRGDPP G
Sbjct: 119 HIENVKGGQEWEQERADPCDVCLHLTCTNVEKSSLDQTLDTAKRLGIKNILALRGDPPRG 178
Query: 436 QDKFVQVEGGFACARDLVK 492
++ ++ + F A DLV+
Sbjct: 179 EEYWIAADKRFQHATDLVR 197
[198][TOP]
>UniRef100_B8DJ94 Methylenetetrahydrofolate reductase n=1 Tax=Desulfovibrio vulgaris
str. 'Miyazaki F' RepID=B8DJ94_DESVM
Length = 291
Score = 98.2 bits (243), Expect = 3e-19
Identities = 52/121 (42%), Positives = 73/121 (60%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MK+ ++I AA++ P +S EFFPPK + ++R+ A P F +T+GAGGS
Sbjct: 1 MKIRDRI--AASTRP---FYSLEFFPPKERENWPGFFATVERLKALDPLFASVTYGAGGS 55
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
T D TL+I ++N +G+E M HLTC E+I D L ++ + NVLALRGD P GQ
Sbjct: 56 TQDNTLEITSHLKNVMGLEPMAHLTCVGATRERIADYLRRLREVNVDNVLALRGDAPKGQ 115
Query: 439 D 441
D
Sbjct: 116 D 116
[199][TOP]
>UniRef100_A4J6K4 Methylenetetrahydrofolate reductase n=1 Tax=Desulfotomaculum
reducens MI-1 RepID=A4J6K4_DESRM
Length = 288
Score = 98.2 bits (243), Expect = 3e-19
Identities = 47/120 (39%), Positives = 69/120 (57%)
Frame = +1
Query: 133 VFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGV 312
V SFE FPPK+ V + E ++ ++ P F +T+GAGGS+ D T +IA ++N +
Sbjct: 13 VISFEIFPPKSTSPVETIYETLEGLIKLEPGFISVTYGAGGSSRDRTKEIAATIKNRYKI 72
Query: 313 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
E + HLTC V +ID L ++ ++NVLALRGDPP + + F A DLV+
Sbjct: 73 EALAHLTCVGQAVNEIDQILNELQEENIENVLALRGDPPADAQNYDFSDSDFKYASDLVR 132
[200][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 97.8 bits (242), Expect = 3e-19
Identities = 54/129 (41%), Positives = 71/129 (55%), Gaps = 4/129 (3%)
Frame = +1
Query: 118 DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQ 297
+ N FS EFFPP+TE G NL+ R DRM A P F DITW G + + K+
Sbjct: 27 ESNDPFFSLEFFPPRTEQGAANLIGRFDRMRAGGPLFVDITWHPAGDPGSDKITSSTKIA 86
Query: 298 NTV----GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 465
TV G++TM+H+TC E I LE K+ G++N+LALRGD + + EGG
Sbjct: 87 GTVLNYCGLDTMLHMTCVKQTKETIKKNLEKTKNLGIRNILALRGD---ADESWGYQEGG 143
Query: 466 FACARDLVK 492
F DLV+
Sbjct: 144 FNYGVDLVR 152
[201][TOP]
>UniRef100_C4BW20 Methylenetetrahydrofolate reductase n=1 Tax=Sebaldella termitidis
ATCC 33386 RepID=C4BW20_9FUSO
Length = 292
Score = 97.4 bits (241), Expect = 4e-19
Identities = 46/122 (37%), Positives = 71/122 (58%)
Frame = +1
Query: 127 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTV 306
K VFSFE FPP L +D + P F +T+GAGG+T T+++A ++N +
Sbjct: 11 KAVFSFEIFPPNENFSSEKLYGVIDELSIQKPDFISVTYGAGGTTKGGTIEMASYIKNKL 70
Query: 307 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDL 486
+E + HLTC ++I++ L ++ N ++N+LALRGD P QD+ + G F A DL
Sbjct: 71 NIEAVTHLTCVGSRKDEIENFLNELERNNIENILALRGDIPKDQDESIYDRGDFLYASDL 130
Query: 487 VK 492
+K
Sbjct: 131 IK 132
[202][TOP]
>UniRef100_A6C2T8 Methylenetetrahydrofolate reductase n=1 Tax=Planctomyces maris DSM
8797 RepID=A6C2T8_9PLAN
Length = 297
Score = 97.4 bits (241), Expect = 4e-19
Identities = 45/117 (38%), Positives = 69/117 (58%)
Frame = +1
Query: 139 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVET 318
S E FPP+ E G L + ++ +V + P+F T+GAGGST+ T+++ +QN +
Sbjct: 15 SVEIFPPRNESGDAELFKTLEELVRYQPAFVSCTYGAGGSTSKRTIELCALIQNQLHNTA 74
Query: 319 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLV 489
H TC N E++ + L+ G+ N++ALRGDPP GQ+ FV +GG A +LV
Sbjct: 75 TAHFTCVNSTREELVEWLQNAVDAGITNIMALRGDPPAGQETFVPADGGLKYANELV 131
[203][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 96.7 bits (239), Expect = 7e-19
Identities = 58/123 (47%), Positives = 74/123 (60%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 64 FSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 123
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+E+++HLTC N +KI L K GL+N++ALRGDP G D + + E GF A D
Sbjct: 124 CGLESILHLTCCNQTKDKITGYLGKAKRLGLKNIMALRGDPV-GAD-WEEEEDGFNYAID 181
Query: 484 LVK 492
LVK
Sbjct: 182 LVK 184
[204][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 96.7 bits (239), Expect = 7e-19
Identities = 58/123 (47%), Positives = 74/123 (60%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 64 FSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 123
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+E+++HLTC N +KI L K GL+N++ALRGDP G D + + E GF A D
Sbjct: 124 CGLESILHLTCCNQTKDKITGYLGKAKRLGLKNIMALRGDPV-GAD-WEEEEDGFNYAID 181
Query: 484 LVK 492
LVK
Sbjct: 182 LVK 184
[205][TOP]
>UniRef100_C1DUH1 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
azorense Az-Fu1 RepID=C1DUH1_SULAA
Length = 291
Score = 96.3 bits (238), Expect = 1e-18
Identities = 49/122 (40%), Positives = 74/122 (60%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MK+++K+ + KV SFEFFPPKT++ +L + ++ + +P+F +T+GAGGS
Sbjct: 1 MKIVDKLKK------EKVSISFEFFPPKTKELEDSLFKTIEELKPINPTFVSVTYGAGGS 54
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
T + T DI KK+ + M HLTC ++I LE K+ G++N+LALRGD P
Sbjct: 55 TREKTRDIVKKIHEETNLTVMAHLTCVGHSKQEIKQILEDYKNIGIENILALRGDIPLSF 114
Query: 439 DK 444
DK
Sbjct: 115 DK 116
[206][TOP]
>UniRef100_C4FKN7 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
yellowstonense SS-5 RepID=C4FKN7_9AQUI
Length = 292
Score = 96.3 bits (238), Expect = 1e-18
Identities = 53/137 (38%), Positives = 75/137 (54%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MK+I+K+ K+ SFEFFPPKTE+ L E + + +P+F +T+GAGGS
Sbjct: 1 MKIIDKLKNT------KISISFEFFPPKTEEAEKTLFETISNLQPLNPTFVSVTYGAGGS 54
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
T + T DI KK+ + M HLTC ++I L+ K G++N+LALRGD P
Sbjct: 55 TREKTRDIVKKIHEETNLTVMAHLTCIGHSKQEILSILDDYKKIGIENILALRGDMPLNF 114
Query: 439 DKFVQVEGGFACARDLV 489
+K G A +LV
Sbjct: 115 EKTDIPSDGCKHASELV 131
[207][TOP]
>UniRef100_O67422 5,10-methylenetetrahydrofolate reductase n=1 Tax=Aquifex aeolicus
RepID=METF_AQUAE
Length = 296
Score = 96.3 bits (238), Expect = 1e-18
Identities = 48/118 (40%), Positives = 73/118 (61%)
Frame = +1
Query: 139 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVET 318
SFEFFPPKTE+G L E + ++ +P+F +T+GAGGST D T +I +K+ +
Sbjct: 15 SFEFFPPKTEEGERQLFETIRKLEKLNPTFVSVTYGAGGSTRDRTRNIVQKIHEETNLTV 74
Query: 319 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
M HLTC E++ D L+ K+ G++N+LALRGD P + + +G A++LV+
Sbjct: 75 MAHLTCIAHTREELIDILQDYKNIGIENILALRGDVPRDKPDWRPPKGACKYAKELVE 132
[208][TOP]
>UniRef100_B6JY06 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6JY06_SCHJY
Length = 626
Score = 95.9 bits (237), Expect = 1e-18
Identities = 49/118 (41%), Positives = 73/118 (61%), Gaps = 1/118 (0%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFXDITWGAGG 255
MK+ E++ + D + +SFEFFPPKT G+ NL RM RM P F +TW + G
Sbjct: 1 MKISEQLEQLPKDD---IHYSFEFFPPKTTIGLDNLTVRMKRMSKTMFPLFSSVTWSSAG 57
Query: 256 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 429
S+A +L + +Q+ GV + +H+TC+N+ E I L+ K+ G++N+LALRGDPP
Sbjct: 58 SSAAESLALCASLQSKFGVTSCLHMTCSNVDKESIKKNLDQAKAYGIRNILALRGDPP 115
[209][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 95.5 bits (236), Expect = 2e-18
Identities = 56/123 (45%), Positives = 74/123 (60%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 102 FSLEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 161
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC E+I L K GL+N+LALRG D++ VEGGF+ A D
Sbjct: 162 CGLETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGAV---GDQWEVVEGGFSYAAD 218
Query: 484 LVK 492
LV+
Sbjct: 219 LVR 221
[210][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 95.5 bits (236), Expect = 2e-18
Identities = 56/123 (45%), Positives = 74/123 (60%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T G VNL+ R DRM + P F D+TW G GS + ++ IA N
Sbjct: 54 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVNF 113
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC N E I L+ K GL+N++ALRGDP G++ + E GF A D
Sbjct: 114 CGLETLLHMTCCNQTKEDITKHLQKAKRLGLKNIMALRGDPT-GEEWEEEAE-GFNYAVD 171
Query: 484 LVK 492
LVK
Sbjct: 172 LVK 174
[211][TOP]
>UniRef100_C0C3T3 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium hylemonae
DSM 15053 RepID=C0C3T3_9CLOT
Length = 289
Score = 95.5 bits (236), Expect = 2e-18
Identities = 43/97 (44%), Positives = 65/97 (67%)
Frame = +1
Query: 139 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVET 318
SFE FPPKT+ G ++L +++ A PSF +T+GAGG T+ T++IA +QN +GV +
Sbjct: 15 SFEVFPPKTDAGYESVLSATEKIAALKPSFISVTYGAGGGTSKNTVNIASHIQNDLGVVS 74
Query: 319 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 429
+ HLTC + E++ +E +K G++NVL LRGD P
Sbjct: 75 LAHLTCASSTKEEVHQVIEKLKEKGIENVLGLRGDIP 111
[212][TOP]
>UniRef100_A8TTR8 Methylenetetrahydrofolate reductase n=1 Tax=alpha proteobacterium
BAL199 RepID=A8TTR8_9PROT
Length = 288
Score = 95.5 bits (236), Expect = 2e-18
Identities = 45/116 (38%), Positives = 68/116 (58%)
Frame = +1
Query: 139 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVET 318
SFEFFPPK E G + L E +DR+ + P F +T+GAGGST + T I +++ G+E
Sbjct: 8 SFEFFPPKDEAGEIKLWETLDRLAPYGPRFVSVTYGAGGSTRERTSRIVTRIKRETGLEP 67
Query: 319 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDL 486
HLTC +++D+ G+++V+ALRGD P G + +GG+A +L
Sbjct: 68 AAHLTCVGATCDEVDEVARGWWDAGIRHVVALRGDAPAGSGGYKPHDGGYANGAEL 123
[213][TOP]
>UniRef100_A6NZH7 Methylenetetrahydrofolate reductase n=1 Tax=Bacteroides capillosus
ATCC 29799 RepID=A6NZH7_9BACE
Length = 286
Score = 95.5 bits (236), Expect = 2e-18
Identities = 48/119 (40%), Positives = 70/119 (58%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MK+I+ + + +KV SFE FPPKT D ++ + + A P F +T+GAGG
Sbjct: 1 MKIIDILSQ------DKVTLSFEVFPPKTSDSYESVAKATQEIAALKPDFMSVTYGAGGG 54
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 435
T+D T+ IA +++ GVE + HLTC + E + L +K +G+ NVLALRGD P G
Sbjct: 55 TSDYTVGIAAGIRDKYGVEPLAHLTCASSTREHVHQVLGKLKESGISNVLALRGDIPEG 113
[214][TOP]
>UniRef100_UPI0001744B57 5,10-methylenetetrahydrofolate reductase n=1 Tax=Verrucomicrobium
spinosum DSM 4136 RepID=UPI0001744B57
Length = 300
Score = 95.1 bits (235), Expect = 2e-18
Identities = 47/119 (39%), Positives = 68/119 (57%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVE 315
FSFEFFPPKT + L E + + A P F +T+GAGG+T ++T D+ +++ T ++
Sbjct: 14 FSFEFFPPKTAETSQALYETISELEAFKPDFVSVTYGAGGTTRELTHDLVVRIKQTTSLD 73
Query: 316 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
+ HLTC E I LE G+ N+LAL GDPP G + + + F A DLV+
Sbjct: 74 PIPHLTCVCHSEEDIGGILERYAEAGVSNILALGGDPPRGLANYEKAKDAFQHASDLVR 132
[215][TOP]
>UniRef100_C4XPB4 Methylenetetrahydrofolate reductase n=1 Tax=Desulfovibrio
magneticus RS-1 RepID=C4XPB4_DESMR
Length = 330
Score = 95.1 bits (235), Expect = 2e-18
Identities = 49/117 (41%), Positives = 66/117 (56%)
Frame = +1
Query: 139 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVET 318
S EFFPPK + +++++ P F +T+GAGGST TL+I +++ G+E
Sbjct: 55 SLEFFPPKEREAWDGFFGVVEKLIPVRPLFVSVTYGAGGSTHAHTLEIVSRLKTAYGLEP 114
Query: 319 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLV 489
M HLTC +KI L + G+ NVLALRGDPP GQ+ FV F A DLV
Sbjct: 115 MAHLTCVGASKDKIRGFLGALAQAGVDNVLALRGDPPKGQETFVPDSEDFQHASDLV 171
[216][TOP]
>UniRef100_B3EPY8 Methylenetetrahydrofolate reductase n=1 Tax=Chlorobium
phaeobacteroides BS1 RepID=B3EPY8_CHLPB
Length = 293
Score = 95.1 bits (235), Expect = 2e-18
Identities = 48/120 (40%), Positives = 68/120 (56%)
Frame = +1
Query: 133 VFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGV 312
VFSFEFFPPK + L + ++ +PS+ +T+GAGGST T D+ K+Q G+
Sbjct: 14 VFSFEFFPPKKTEDWGKLFHTISELIPFNPSYVSVTYGAGGSTRSRTHDLVTKIQRETGL 73
Query: 313 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
+ HLTC + + + LE ++ G+ NVLALRGD P G + + F A DLVK
Sbjct: 74 TVVSHLTCICSGKKDVAEILEDYRTQGITNVLALRGDLPPGSTSYEEATKDFPHAVDLVK 133
[217][TOP]
>UniRef100_B2V845 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
sp. YO3AOP1 RepID=B2V845_SULSY
Length = 291
Score = 95.1 bits (235), Expect = 2e-18
Identities = 53/137 (38%), Positives = 76/137 (55%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MK+I+K+ KV SFEFFPPKTE+ L E + + +P+F +T+GAGGS
Sbjct: 1 MKIIDKLKNT------KVSISFEFFPPKTEEAEKTLFETISNLQPLNPTFVSVTYGAGGS 54
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 438
T + T DI KK+ + M HLTC ++I L+ + G++N+LALRGD P
Sbjct: 55 TREKTRDIVKKIHEETKLTVMAHLTCIGHSKQEILSILDDYEKIGIENILALRGDIPLNF 114
Query: 439 DKFVQVEGGFACARDLV 489
+K + G A +LV
Sbjct: 115 EKSDILSDGCKHASELV 131
[218][TOP]
>UniRef100_C1ZF18 Methylenetetrahydrofolate reductase n=1 Tax=Planctomyces
limnophilus DSM 3776 RepID=C1ZF18_PLALI
Length = 310
Score = 95.1 bits (235), Expect = 2e-18
Identities = 48/118 (40%), Positives = 70/118 (59%)
Frame = +1
Query: 139 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVET 318
S E FPPKT +G L + + ++P+F T+GAGGST TLD +++ + VGV
Sbjct: 27 SIEIFPPKTAEGDAALRQALQEFSTYNPAFVSCTYGAGGSTRSRTLDWCREIIDRVGVAP 86
Query: 319 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
H TC +++ D L G++N++ALRGD P G+ +F VEGGF+ AR LV+
Sbjct: 87 TAHFTCVGSNSDELIDWLGQAWQLGVRNIMALRGDVPQGETEFKAVEGGFSHARQLVE 144
[219][TOP]
>UniRef100_A3ZZ23 Methylenetetrahydrofolate reductase n=1 Tax=Blastopirellula marina
DSM 3645 RepID=A3ZZ23_9PLAN
Length = 293
Score = 95.1 bits (235), Expect = 2e-18
Identities = 48/124 (38%), Positives = 71/124 (57%)
Frame = +1
Query: 121 PNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQN 300
P ++ SFE FPPKT+ G +L+ ++++V P + T+GAGGST TLDI +K++
Sbjct: 9 PGRLGLSFELFPPKTDKGDASLMLHVEKLVKFKPDYITCTYGAGGSTRGKTLDIVEKVKQ 68
Query: 301 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACAR 480
GV HLT + V + L + G+ ++ALRGDPP GQ KF G + A
Sbjct: 69 VFGVPVASHLTLVDSTVGDLRLYLAEAERRGVDYIVALRGDPPQGQTKFRPTAKGLSYAS 128
Query: 481 DLVK 492
+LV+
Sbjct: 129 ELVE 132
[220][TOP]
>UniRef100_A8Q9P3 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8Q9P3_MALGO
Length = 515
Score = 95.1 bits (235), Expect = 2e-18
Identities = 48/91 (52%), Positives = 58/91 (63%)
Frame = +1
Query: 220 PSFXDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQ 399
P F DITW AGG T+D+T + K +Q GVET MHLTCTNMP KI+ AL K G +
Sbjct: 6 PEFVDITWNAGGRTSDMTTQLVKTVQTYFGVETCMHLTCTNMPRSKIEVALREAKEFGCR 65
Query: 400 NVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
NVLALRGDPP + GF+ A +LV+
Sbjct: 66 NVLALRGDPPAAGSPWEPHAAGFSHAFELVQ 96
[221][TOP]
>UniRef100_A1BH63 Methylenetetrahydrofolate reductase n=1 Tax=Chlorobium
phaeobacteroides DSM 266 RepID=A1BH63_CHLPD
Length = 289
Score = 94.7 bits (234), Expect = 3e-18
Identities = 48/120 (40%), Positives = 66/120 (55%)
Frame = +1
Query: 133 VFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGV 312
VFSFEFFPPK E+ L + + + +PS+ +T+GAGGST T D+ ++Q G+
Sbjct: 14 VFSFEFFPPKKEEEWNTLFATIASLTSLNPSYVSVTYGAGGSTRSKTHDLVTRIQKETGI 73
Query: 313 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
+ HLTC E+ LE NG+ NVLALRGD P G + F A DL++
Sbjct: 74 TVVSHLTCVCSDREETSSILENYLENGINNVLALRGDKPQGVATLAEAIKDFEHAADLIR 133
[222][TOP]
>UniRef100_Q1K0Z7 Methylenetetrahydrofolate reductase n=1 Tax=Desulfuromonas
acetoxidans DSM 684 RepID=Q1K0Z7_DESAC
Length = 289
Score = 94.7 bits (234), Expect = 3e-18
Identities = 50/125 (40%), Positives = 68/125 (54%)
Frame = +1
Query: 118 DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQ 297
D ++ SFEFFPPKT G L + + + +PS +T+GAGGST T D+ ++
Sbjct: 8 DQGRISLSFEFFPPKTVVGGERLFDNIAELAPLAPSSVSVTYGAGGSTRSQTHDLVLRIH 67
Query: 298 NTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACA 477
N GV + H TC + + L + NG++NVLALRGDPP + GFA A
Sbjct: 68 NETGVTVVPHQTCVAATRDDVAMILAEYEQNGIENVLALRGDPPLDDPDWTPPVNGFAHA 127
Query: 478 RDLVK 492
DLVK
Sbjct: 128 IDLVK 132
[223][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 94.4 bits (233), Expect = 4e-18
Identities = 54/123 (43%), Positives = 75/123 (60%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T G VNL+ R D+M A P F D+TW G GS + ++ IA +
Sbjct: 57 FSLEFFPPRTAQGAVNLISRFDQMGAGGPLFVDVTWHPAGDPGSDKETSSMIIANTAVDY 116
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC + ++I L K GL+N++ALRGDP D++ + EGGF A D
Sbjct: 117 CGLETVLHMTCCHQTRDEITRHLHKAKRLGLKNIMALRGDPI--GDEWEEEEGGFNHAVD 174
Query: 484 LVK 492
LVK
Sbjct: 175 LVK 177
[224][TOP]
>UniRef100_Q60CG9 Methylenetetrahydrofolate reductase n=1 Tax=Methylococcus
capsulatus RepID=Q60CG9_METCA
Length = 289
Score = 94.4 bits (233), Expect = 4e-18
Identities = 48/119 (40%), Positives = 71/119 (59%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVE 315
FSFEFFPPKTE+ NL + ++ P F +T+GAGGST + T + A ++Q T G+E
Sbjct: 15 FSFEFFPPKTEEATENLRRTLTKLAPLKPRFCSVTFGAGGSTREKTFETALEIQQTTGIE 74
Query: 316 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
HL+C I + LE +S+G+++++ALRGD P G + G F A +LV+
Sbjct: 75 CAPHLSCIASTRRSIREILEAYRSHGIRHIVALRGDMPSG----MLSAGEFRHANELVE 129
[225][TOP]
>UniRef100_C6JIG2 Methylenetetrahydrofolate reductase n=1 Tax=Fusobacterium varium
ATCC 27725 RepID=C6JIG2_FUSVA
Length = 293
Score = 94.4 bits (233), Expect = 4e-18
Identities = 46/121 (38%), Positives = 73/121 (60%)
Frame = +1
Query: 127 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTV 306
K + SFE FPP + + ++ +D + P F +T+GAGG+T T++IA K++N
Sbjct: 11 KTIVSFEVFPPNSIYSLEDVYSSIDELAKLQPDFISVTYGAGGATRGNTVEIASKIKNNN 70
Query: 307 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDL 486
+E + HLTC +IDD L+ +++N ++N+LALRGD P +D EG F A+DL
Sbjct: 71 KIEALAHLTCLGAKKNEIDDILKQLRANNIENILALRGDKP--KDSTPIGEGDFKYAQDL 128
Query: 487 V 489
+
Sbjct: 129 I 129
[226][TOP]
>UniRef100_A4SE12 Methylenetetrahydrofolate reductase n=1 Tax=Chlorobium
phaeovibrioides DSM 265 RepID=A4SE12_PROVI
Length = 289
Score = 94.0 bits (232), Expect = 5e-18
Identities = 49/123 (39%), Positives = 69/123 (56%)
Frame = +1
Query: 124 NKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNT 303
+K VFSFEFFPPK + L E + + +PS+ +T+GAGGST T D+ ++Q
Sbjct: 11 HKPVFSFEFFPPKKDADWETLFETITALSPLNPSYVSVTYGAGGSTRTRTHDLVTRIQKE 70
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ + HLTC + + LE +S+G+ NVLALRGD P G + F A D
Sbjct: 71 TGLSVVSHLTCIASTSGETGEILENYQSHGINNVLALRGDKPTGTESIADAVKDFPHAID 130
Query: 484 LVK 492
LV+
Sbjct: 131 LVR 133
[227][TOP]
>UniRef100_B6B3G2 Methylenetetrahydrofolate reductase n=1 Tax=Rhodobacterales
bacterium HTCC2083 RepID=B6B3G2_9RHOB
Length = 288
Score = 94.0 bits (232), Expect = 5e-18
Identities = 45/118 (38%), Positives = 69/118 (58%)
Frame = +1
Query: 139 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVET 318
SFEFFPP++ + L + + + P+F +T+GAGG+T D+T D + + G+
Sbjct: 7 SFEFFPPQSLEASFRLWDTVQVLSPLDPTFVSVTYGAGGTTRDLTRDAVATLHKSSGLNV 66
Query: 319 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
HLTC N E+ + G++ +LALRGD P GQD+F VEGGFA + +L++
Sbjct: 67 AAHLTCVNATREETLGIAKEFAKAGVREILALRGDAPKGQDRFTPVEGGFANSVELIE 124
[228][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 94.0 bits (232), Expect = 5e-18
Identities = 54/124 (43%), Positives = 77/124 (62%), Gaps = 5/124 (4%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFXDITWGAGGSTADVTLDIAKKMQNTVGV 312
+SFEFFPPKTE G+ NLL R+DRM P F D+TWG+ ++A T+ +A Q +GV
Sbjct: 41 YSFEFFPPKTEAGLDNLLTRIDRMAQRLDPLFIDVTWGSDKTSAR-TMALASHAQKYLGV 99
Query: 313 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFV--QVEGGFACAR-- 480
+ ++HL+C M +++ L+ K G+ N+LALRGDPP + + V GG C R
Sbjct: 100 DVLLHLSCQGMTRDQLIRVLDQAKVLGIHNILALRGDPPKAKKHWQVGDVSGG-ECERAI 158
Query: 481 DLVK 492
DLV+
Sbjct: 159 DLVR 162
[229][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 94.0 bits (232), Expect = 5e-18
Identities = 53/154 (34%), Positives = 84/154 (54%), Gaps = 17/154 (11%)
Frame = +1
Query: 82 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFXDITWGAGGS 258
++ EK+++ S + V+S EFFPP+T G+ NL R+ RM A P + +TWG GGS
Sbjct: 11 RIDEKLND---STQDAYVWSLEFFPPRTALGLANLCARVARMSEALQPGWVHVTWGTGGS 67
Query: 259 TADVTLDIAKKMQNTV----------------GVETMMHLTCTNMPVEKIDDALETIKSN 390
T D ++++A ++Q V + +HLTCTN+ +D L+ +
Sbjct: 68 TRDASMELAARVQKGVYDPLEDYTNVKERRKGACDVCLHLTCTNVERAYLDATLDEARQI 127
Query: 391 GLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
G++N+LALRGDPP + +V + A DLV+
Sbjct: 128 GIRNILALRGDPPRSDEYWVATDQRLQNATDLVR 161
[230][TOP]
>UniRef100_Q3A3T2 Methylenetetrahydrofolate reductase n=1 Tax=Pelobacter carbinolicus
DSM 2380 RepID=Q3A3T2_PELCD
Length = 301
Score = 93.6 bits (231), Expect = 6e-18
Identities = 45/125 (36%), Positives = 71/125 (56%)
Frame = +1
Query: 118 DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQ 297
D + FSFEFFPPKT+ L E + ++ + P F +T+GAGGST + T D+ ++
Sbjct: 8 DRYETTFSFEFFPPKTDKAAERLYETIRQLESLHPHFTSVTYGAGGSTRERTHDLVMRIH 67
Query: 298 NTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACA 477
+ ++ + HLTC + P ++I L+ G+ N+LAL GDPP + + + F A
Sbjct: 68 ESSSLDPIPHLTCVSSPEQEIHQILKRYAEAGISNILALAGDPPPDMPHYDRSQDAFPHA 127
Query: 478 RDLVK 492
DLV+
Sbjct: 128 ADLVR 132
[231][TOP]
>UniRef100_Q0YRM1 Methylenetetrahydrofolate reductase n=1 Tax=Chlorobium ferrooxidans
DSM 13031 RepID=Q0YRM1_9CHLB
Length = 328
Score = 93.6 bits (231), Expect = 6e-18
Identities = 51/136 (37%), Positives = 76/136 (55%)
Frame = +1
Query: 85 VIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTA 264
++++I +AA K VFSFEFFPPK ++ L + + + +PS+ +T+GAGGST
Sbjct: 41 LVKEILDAAV----KPVFSFEFFPPKKDEEWETLFKTIAALSPLNPSYVSVTYGAGGSTR 96
Query: 265 DVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDK 444
T D+ K+Q G+ + HLTC E+ L+ + NG+ NVLALRGD P G
Sbjct: 97 SRTHDLVTKIQRETGLTVVSHLTCICSDREETGSILQNYRDNGINNVLALRGDKPAGTAT 156
Query: 445 FVQVEGGFACARDLVK 492
+ F A DL++
Sbjct: 157 LAEAIKDFPHAIDLIR 172
[232][TOP]
>UniRef100_A3WED2 Methylenetetrahydrofolate reductase n=1 Tax=Erythrobacter sp. NAP1
RepID=A3WED2_9SPHN
Length = 309
Score = 93.6 bits (231), Expect = 6e-18
Identities = 50/142 (35%), Positives = 75/142 (52%), Gaps = 8/142 (5%)
Frame = +1
Query: 88 IEKIHEAAA-------SD-PNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW 243
+ ++HEA SD P + SFEFFPPKTE L + + P F +T+
Sbjct: 5 LNQLHEAKTALDAPLFSDLPGDIDISFEFFPPKTEKMGETLWSSVATLSPLGPRFVSVTY 64
Query: 244 GAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGD 423
GAGGST + T + ++QN G+ HLTC N E++++ G+++++ALRGD
Sbjct: 65 GAGGSTRERTHEQVVRIQNEAGIPAAAHLTCVNATKEEVNEVARHYWEEGIRHIVALRGD 124
Query: 424 PPHGQDKFVQVEGGFACARDLV 489
PP G + GG+ A DL+
Sbjct: 125 PPDGASAYTPHPGGYENAADLI 146
[233][TOP]
>UniRef100_A4U3F0 Methylenetetrahydrofolate reductase n=1 Tax=Magnetospirillum
gryphiswaldense RepID=A4U3F0_9PROT
Length = 293
Score = 93.2 bits (230), Expect = 8e-18
Identities = 49/128 (38%), Positives = 70/128 (54%)
Frame = +1
Query: 109 AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAK 288
AA+ V SFEFFPPKTE L E + R+ +PSF +T+GAGG+T + T D
Sbjct: 6 AAASAKPVSVSFEFFPPKTEKMQETLWECVKRLEPLAPSFVSVTYGAGGTTRERTHDTVV 65
Query: 289 KMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGF 468
++ ++ HLTC ++DD G+++++ALRGD P G + GG+
Sbjct: 66 RIARESSLKPAAHLTCVGHSQGEVDDIARRYWDEGIRHIVALRGDAPEGSGAYQPTPGGY 125
Query: 469 ACARDLVK 492
A A DLVK
Sbjct: 126 AYAVDLVK 133
[234][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 92.8 bits (229), Expect = 1e-17
Identities = 54/123 (43%), Positives = 74/123 (60%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + ++ IA +
Sbjct: 54 FSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMIIANTAVDY 113
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC+ ++I L K GL+N+LALRGDP D++ + E F+ A D
Sbjct: 114 CGLETVLHMTCSQQNRDEITSHLHKAKRLGLKNILALRGDPI--GDEWEEEENCFSHAVD 171
Query: 484 LVK 492
LVK
Sbjct: 172 LVK 174
[235][TOP]
>UniRef100_B3E425 Methylenetetrahydrofolate reductase n=1 Tax=Geobacter lovleyi SZ
RepID=B3E425_GEOLS
Length = 290
Score = 92.8 bits (229), Expect = 1e-17
Identities = 47/117 (40%), Positives = 67/117 (57%)
Frame = +1
Query: 139 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVET 318
S E+FPPK + ++R+ + +P F +T+GAGGS D TL+I +MQ +G+ET
Sbjct: 15 SVEYFPPKERQDWPAFFKVVERLASLNPLFASVTYGAGGSNQDATLEIVTQMQQQLGLET 74
Query: 319 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLV 489
M HLTC +++ L+ + G+QN+LALRGDPP E F A DLV
Sbjct: 75 MAHLTCVGAQAGRLNRFLDDLSKVGIQNILALRGDPPLETPVEQLTESPFHFASDLV 131
[236][TOP]
>UniRef100_A4RH85 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RH85_MAGGR
Length = 662
Score = 92.8 bits (229), Expect = 1e-17
Identities = 46/87 (52%), Positives = 62/87 (71%), Gaps = 1/87 (1%)
Frame = +1
Query: 172 GVVNLLERMDRMV-AHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMP 348
G NL +R+DRM A P F ++TWGAGGSTA +L++A+ Q + + T +HLTCTNM
Sbjct: 2 GFSNLRDRLDRMARALRPLFVNVTWGAGGSTAQKSLELAEICQRELALTTCLHLTCTNMS 61
Query: 349 VEKIDDALETIKSNGLQNVLALRGDPP 429
+ ID ALE K+ G++N+LALRGDPP
Sbjct: 62 RKLIDKALEDAKALGIRNILALRGDPP 88
[237][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 92.4 bits (228), Expect = 1e-17
Identities = 55/122 (45%), Positives = 72/122 (59%), Gaps = 4/122 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T G VNL+ R DRM + P F D+TW G GS + ++ IA N
Sbjct: 54 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMVIASAAVNF 113
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC N E I L K GL+N++ALRGDP G++ + E GF A D
Sbjct: 114 CGLETILHMTCCNQTKEDITKHLHKAKHLGLKNIMALRGDPT-GEEWEEEAE-GFNYAVD 171
Query: 484 LV 489
LV
Sbjct: 172 LV 173
[238][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 92.4 bits (228), Expect = 1e-17
Identities = 55/122 (45%), Positives = 72/122 (59%), Gaps = 4/122 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T G VNL+ R DRM + P F D+TW G GS + ++ IA N
Sbjct: 54 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMVIASAAVNF 113
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC N E I L K GL+N++ALRGDP G++ + E GF A D
Sbjct: 114 CGLETILHMTCCNQTKEDITKHLHKAKHLGLKNIMALRGDPT-GEEWEEEAE-GFNYAVD 171
Query: 484 LV 489
LV
Sbjct: 172 LV 173
[239][TOP]
>UniRef100_Q7UNJ7 Methylenetetrahydrofolate reductase n=1 Tax=Rhodopirellula baltica
RepID=Q7UNJ7_RHOBA
Length = 294
Score = 92.4 bits (228), Expect = 1e-17
Identities = 44/118 (37%), Positives = 69/118 (58%)
Frame = +1
Query: 139 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVET 318
SFE FPPKT +GV L + ++R++ P + T+GAGGS+ TL++ +K++ +
Sbjct: 19 SFELFPPKTSEGVELLCKNVERLMQFGPKYFTCTYGAGGSSQGTTLEVLQKVKQITKLPV 78
Query: 319 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
HLTC V++++ L G+ ++ALRGDPP G +F EGG A +LV+
Sbjct: 79 ASHLTCVGSTVKELEAYLTEAGRIGVDYIVALRGDPPKGTTQFEVTEGGLKYANELVE 136
[240][TOP]
>UniRef100_C0QT51 Methylenetetrahydrofolate reductase n=1 Tax=Persephonella marina
EX-H1 RepID=C0QT51_PERMH
Length = 293
Score = 92.4 bits (228), Expect = 1e-17
Identities = 49/118 (41%), Positives = 70/118 (59%), Gaps = 1/118 (0%)
Frame = +1
Query: 139 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVET 318
SFEFFPPKT +G L + + +P+F +T+GAGGST + T+ + K++ +
Sbjct: 15 SFEFFPPKTPEGEDQLFRTIKDLEKLNPTFVSVTYGAGGSTRERTIRVVKRIHEQCNLTV 74
Query: 319 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDK-FVQVEGGFACARDLV 489
M HLTC ++I D L+ K G+QN+LALRGD P GQ++ FV G A +LV
Sbjct: 75 MAHLTCIGHSKKEIYDILKGYKDIGIQNILALRGDIPQGQEESFVFPPDGCRYANELV 132
[241][TOP]
>UniRef100_A9KQY7 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium
phytofermentans ISDg RepID=A9KQY7_CLOPH
Length = 286
Score = 92.4 bits (228), Expect = 1e-17
Identities = 48/123 (39%), Positives = 73/123 (59%), Gaps = 1/123 (0%)
Frame = +1
Query: 127 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTAD-VTLDIAKKMQNT 303
K VFS E FPPK + V ++ + + +P F +T+GAGG+ AD T DIA +Q+
Sbjct: 11 KTVFSLEVFPPKKDSPVESIYRVLGELTKLNPDFISVTYGAGGNAADHTTCDIASYIQSN 70
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G++ + HLTC N E +D LE +KS G+ N+LALRGD ++ ++ + F A +
Sbjct: 71 YGIDALTHLTCVNSTKEDMDTTLEYLKSQGIMNILALRGD----RNPEIEPKKDFTYASN 126
Query: 484 LVK 492
LV+
Sbjct: 127 LVE 129
[242][TOP]
>UniRef100_C1SKU9 Methylenetetrahydrofolate reductase n=1 Tax=Denitrovibrio
acetiphilus DSM 12809 RepID=C1SKU9_9BACT
Length = 284
Score = 92.4 bits (228), Expect = 1e-17
Identities = 47/118 (39%), Positives = 69/118 (58%)
Frame = +1
Query: 139 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVET 318
SFEFFPPK ++ L E + ++ ++P F +T+GAGGST + TL+ K+M+
Sbjct: 14 SFEFFPPKKQESEQVLFETIKKLRRYNPEFVSVTYGAGGSTTEKTLEWTKRMKEDHDYSV 73
Query: 319 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 492
MMH TC ID A +++K + + N+LALRGD P G +F + F A DLV+
Sbjct: 74 MMHFTCIGADAAVIDSATQSLKESRVDNILALRGDIPAGTTEFKPTK-DFQYAADLVR 130
[243][TOP]
>UniRef100_C3WGW3 Methylenetetrahydrofolate reductase n=1 Tax=Fusobacterium sp.
2_1_31 RepID=C3WGW3_9FUSO
Length = 288
Score = 92.0 bits (227), Expect = 2e-17
Identities = 47/117 (40%), Positives = 75/117 (64%)
Frame = +1
Query: 139 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVET 318
SFE FPP + G+ + +D + P + +T+GAGG+T T++IA +++N GVE+
Sbjct: 15 SFEVFPPNDKVGLEQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTVEIADRIKNQNGVES 74
Query: 319 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLV 489
+ HLTC E+ID LE ++ + ++N+LALRGD P D+ ++V G F+ ARDL+
Sbjct: 75 VAHLTCIGAKKEEIDKVLEDLEKHNIENILALRGDYP--VDRELEV-GDFSYARDLI 128
[244][TOP]
>UniRef100_B5CM26 Methylenetetrahydrofolate reductase n=1 Tax=Ruminococcus lactaris
ATCC 29176 RepID=B5CM26_9FIRM
Length = 289
Score = 92.0 bits (227), Expect = 2e-17
Identities = 43/119 (36%), Positives = 73/119 (61%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGS 258
MK+I++++E +++ SFE FPPKT+ G N+ D + PS+ +T+GAGG
Sbjct: 1 MKIIDRLNE------DRINISFEVFPPKTDAGFANVQRATDEIAKLDPSYISVTYGAGGG 54
Query: 259 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 435
T+ T IA +++ + V ++ HLTC + E++ + + +K G++N+LALRGD P G
Sbjct: 55 TSKNTAKIASHIKDDLHVLSLAHLTCASSTKEEVREVIRNLKELGIENILALRGDIPEG 113
[245][TOP]
>UniRef100_UPI00005884BD PREDICTED: similar to Mthfr-prov protein, partial n=1
Tax=Strongylocentrotus purpuratus RepID=UPI00005884BD
Length = 326
Score = 91.7 bits (226), Expect = 2e-17
Identities = 58/146 (39%), Positives = 79/146 (54%), Gaps = 8/146 (5%)
Frame = +1
Query: 79 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDIT------ 240
M++ EKI AS FS EFFPP+T G VNL+ R H +I
Sbjct: 56 MRLSEKIANRIASKDRW--FSLEFFPPRTASGAVNLVGRY----VHMGGGGEIKVMEMYY 109
Query: 241 -WGAGGSTAD-VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLAL 414
WG GG+ + V+++IA+ M N G++TM+H+ C + E I LE K G++N+LAL
Sbjct: 110 PWGGGGAGEEQVSMEIARTMLNYCGLDTMLHMCCVSQSAEVITRHLEWAKECGIRNILAL 169
Query: 415 RGDPPHGQDKFVQVEGGFACARDLVK 492
RGD P D++ GGF A DLVK
Sbjct: 170 RGDVPGHTDEWEPTPGGFNYATDLVK 195
[246][TOP]
>UniRef100_Q6AMT4 Methylenetetrahydrofolate reductase n=1 Tax=Desulfotalea
psychrophila RepID=Q6AMT4_DESPS
Length = 296
Score = 91.7 bits (226), Expect = 2e-17
Identities = 45/118 (38%), Positives = 68/118 (57%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTVGVE 315
FSFEFFPPK ++G LL+ + +++ +PS+ IT+GAGGST + T D+ +++ +
Sbjct: 14 FSFEFFPPKNKEGEERLLQTLKQLIPLAPSYISITYGAGGSTREKTHDLVLRIRRETNLT 73
Query: 316 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLV 489
+ HLTC +I L+ G+ N+LAL+GDPP D + F A DLV
Sbjct: 74 VVSHLTCVGSSRAEILRILKRYDEAGIHNILALKGDPPAPTDDAAETVDDFLYAADLV 131
[247][TOP]
>UniRef100_B9NMM3 Methylenetetrahydrofolate reductase n=1 Tax=Rhodobacteraceae
bacterium KLH11 RepID=B9NMM3_9RHOB
Length = 288
Score = 91.7 bits (226), Expect = 2e-17
Identities = 43/121 (35%), Positives = 71/121 (58%)
Frame = +1
Query: 127 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNTV 306
K SFEFFPP+T + L + + + +P F +T+GAGG+T ++T D + +
Sbjct: 3 KPEISFEFFPPQTLEASFRLWDTVQTLAPLNPRFVSVTYGAGGTTRELTRDAVATLHKSS 62
Query: 307 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDL 486
G++ HLTC + ++ + +T G+Q+++ALRGDPP GQD+F GFA + +L
Sbjct: 63 GLQVAAHLTCVDASRQETLEIADTFARAGVQDIVALRGDPPKGQDQFTPHPEGFANSVEL 122
Query: 487 V 489
+
Sbjct: 123 I 123
[248][TOP]
>UniRef100_B5JFK7 Methylenetetrahydrofolate reductase n=1 Tax=Verrucomicrobiae
bacterium DG1235 RepID=B5JFK7_9BACT
Length = 296
Score = 91.7 bits (226), Expect = 2e-17
Identities = 43/122 (35%), Positives = 71/122 (58%)
Frame = +1
Query: 124 NKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITWGAGGSTADVTLDIAKKMQNT 303
++ + S EFFPPK+++ + L+E + + +SP F +T+GAGGST D + + +++
Sbjct: 13 SRPLLSVEFFPPKSDEALDELVESAEELAPYSPDFVSVTYGAGGSTRDRSAKACQLLRDE 72
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
M HLTC ++ + + + G +N++ALRGDPP + FV + GFA A D
Sbjct: 73 HDFNIMPHLTCVGASRGELAETINGLYEAGYRNIMALRGDPPKDSNSFVVAKDGFAHASD 132
Query: 484 LV 489
LV
Sbjct: 133 LV 134
[249][TOP]
>UniRef100_UPI000194E904 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH), partial n=1 Tax=Taeniopygia guttata
RepID=UPI000194E904
Length = 345
Score = 91.3 bits (225), Expect = 3e-17
Identities = 54/123 (43%), Positives = 76/123 (61%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T + VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 62 FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY 121
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC + ++I L+ K GL+N++ALRGDP G++ +V+ GF A D
Sbjct: 122 CGLETILHMTCCHQTRDEITGHLQKAKRLGLKNIMALRGDPV-GEEWEEEVD-GFNHAVD 179
Query: 484 LVK 492
LVK
Sbjct: 180 LVK 182
[250][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 91.3 bits (225), Expect = 3e-17
Identities = 54/123 (43%), Positives = 76/123 (61%), Gaps = 4/123 (3%)
Frame = +1
Query: 136 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFXDITW---GAGGSTADV-TLDIAKKMQNT 303
FS EFFPP+T + VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 62 FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY 121
Query: 304 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 483
G+ET++H+TC + ++I L+ K GL+N++ALRGDP G++ +V+ GF A D
Sbjct: 122 CGLETIVHMTCCHQTKDEITGHLQKAKRLGLKNIMALRGDPV-GEEWEEEVD-GFNHAVD 179
Query: 484 LVK 492
LVK
Sbjct: 180 LVK 182