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[1][TOP]
>UniRef100_C6T731 Methylenetetrahydrofolate reductase n=1 Tax=Glycine max
RepID=C6T731_SOYBN
Length = 344
Score = 138 bits (348), Expect = 2e-31
Identities = 81/129 (62%), Positives = 88/129 (68%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
K+IEKIH AA++DPNRVVFSFEFFPPKTEDGV NL ERMDRMV H+PS
Sbjct: 2 KIIEKIH-AASADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVVHNPSFCDITWSAGGTT 60
Query: 181 RGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQ 360
+ I K I V + MP EK+D AL TIKSNGLQNVLALRGDPPHGQ
Sbjct: 61 ADLTLEIANKMQNIVCV-ETMMHLTCTNMPVEKIDHALHTIKSNGLQNVLALRGDPPHGQ 119
Query: 361 DKFVQVEGG 387
DKFVQVEGG
Sbjct: 120 DKFVQVEGG 128
Score = 62.8 bits (151), Expect = 1e-08
Identities = 40/115 (34%), Positives = 58/115 (50%), Gaps = 8/115 (6%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNIRY--------CQKDAEYRRCGNHDAPHLHQRCLMRRWTMLSRP 301
FCDITW AGG+TA + C + + C N + + +
Sbjct: 49 FCDITWSAGGTTADLTLEIANKMQNIVCVETMMHLTCTNMPVEKIDH-------ALHTIK 101
Query: 302 SSPMASRMCLLFEVIPHMVRTNSSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
S+ + + + L + P + + + FACARDLV+HIRAK+GDYFGIT+AGY
Sbjct: 102 SNGLQNVLALRGD--PPHGQDKFVQVEGGFACARDLVQHIRAKYGDYFGITVAGY 154
[2][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 129 bits (324), Expect = 1e-28
Identities = 79/141 (56%), Positives = 88/141 (62%), Gaps = 12/141 (8%)
Frame = +1
Query: 1 KVIEKIHEAAA------------SDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPS 144
KVI+KI EAA S N+VVFSFEFFPPKTEDGV NL ERMDRMVAH+PS
Sbjct: 2 KVIDKIREAAGGGGDANGNGGDNSSSNKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPS 61
Query: 145 VL*YYVGCWRINRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQN 324
G + I K I V + MP EK+D ALETIKSNG+QN
Sbjct: 62 FCDITWGAGGSTADLTLDIANKMQNIICV-ETMMHLTCTNMPVEKIDHALETIKSNGIQN 120
Query: 325 VLALRGDPPHGQDKFVQVEGG 387
VLALRGDPPHGQDKFVQ++GG
Sbjct: 121 VLALRGDPPHGQDKFVQIQGG 141
Score = 63.2 bits (152), Expect = 9e-09
Identities = 42/110 (38%), Positives = 54/110 (49%), Gaps = 3/110 (2%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNIRYCQKDAEYRRCGNHDAPHLHQRCLMRRWTMLSRPSSPMAS-- 319
FCDITWGAGGSTA + K + C +H C + + S
Sbjct: 62 FCDITWGAGGSTADLTLDIANK-MQNIICVE---TMMHLTCTNMPVEKIDHALETIKSNG 117
Query: 320 -RMCLLFEVIPHMVRTNSSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
+ L P + + + FACA DLVKHIR+K+GDYFGIT+AGY
Sbjct: 118 IQNVLALRGDPPHGQDKFVQIQGGFACALDLVKHIRSKYGDYFGITVAGY 167
[3][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 128 bits (322), Expect = 2e-28
Identities = 78/139 (56%), Positives = 89/139 (64%), Gaps = 9/139 (6%)
Frame = +1
Query: 1 KVIEKIHEAAA---------SDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL* 153
KVI+KI AAA S N+VVFSFEFFPPKT+DGV NL ERMDRMV+H+PS
Sbjct: 2 KVIDKIRAAAAAGDSNGGDSSSNNKVVFSFEFFPPKTDDGVDNLFERMDRMVSHNPSFCD 61
Query: 154 YYVGCWRINRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLA 333
G + I K I V + MP EK+D ALETIKSNG+QNVLA
Sbjct: 62 ITWGAGGSTADLTLDIANKMQNIICV-ETMMHLTCTNMPVEKIDHALETIKSNGIQNVLA 120
Query: 334 LRGDPPHGQDKFVQVEGGL 390
LRGDPPHGQDKFVQ++GGL
Sbjct: 121 LRGDPPHGQDKFVQIQGGL 139
Score = 60.8 bits (146), Expect = 4e-08
Identities = 41/110 (37%), Positives = 53/110 (48%), Gaps = 3/110 (2%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNIRYCQKDAEYRRCGNHDAPHLHQRCLMRRWTMLSRPSSPMAS-- 319
FCDITWGAGGSTA + K + C +H C + + S
Sbjct: 59 FCDITWGAGGSTADLTLDIANK-MQNIICVE---TMMHLTCTNMPVEKIDHALETIKSNG 114
Query: 320 -RMCLLFEVIPHMVRTNSSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
+ L P + + + ACA DLVKHIR+K+GDYFGIT+AGY
Sbjct: 115 IQNVLALRGDPPHGQDKFVQIQGGLACALDLVKHIRSKYGDYFGITVAGY 164
[4][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 127 bits (318), Expect = 5e-28
Identities = 75/132 (56%), Positives = 88/132 (66%), Gaps = 3/132 (2%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
KVIEKI +AA + +VVFSFEFFPPKTEDGV NL ERMDRMVAH P+ G
Sbjct: 2 KVIEKIRDAATEE-GKVVFSFEFFPPKTEDGVDNLFERMDRMVAHGPAFCDITWGAGGST 60
Query: 181 RGM*H*ILPKRCR---IP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
+ I K + + CT+ MP EK+D AL+TIKSNG+QNVLALRGDPP
Sbjct: 61 ADLTLEISNKMQNMICVETMMHLTCTN----MPVEKIDHALDTIKSNGIQNVLALRGDPP 116
Query: 352 HGQDKFVQVEGG 387
HGQDKFVQ++GG
Sbjct: 117 HGQDKFVQIQGG 128
Score = 63.9 bits (154), Expect = 5e-09
Identities = 42/110 (38%), Positives = 54/110 (49%), Gaps = 3/110 (2%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNIRYCQKDAEYRRCGNHDAPHLHQRCLMRRWTMLSRPSSPMAS-- 319
FCDITWGAGGSTA + K + C +H C + + S
Sbjct: 49 FCDITWGAGGSTADLTLEISNK-MQNMICVE---TMMHLTCTNMPVEKIDHALDTIKSNG 104
Query: 320 -RMCLLFEVIPHMVRTNSSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
+ L P + + + FACA DLV+HIRAK+GDYFGIT+AGY
Sbjct: 105 IQNVLALRGDPPHGQDKFVQIQGGFACALDLVQHIRAKYGDYFGITVAGY 154
[5][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 127 bits (318), Expect = 5e-28
Identities = 75/132 (56%), Positives = 88/132 (66%), Gaps = 3/132 (2%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
KVIEKI +AA + +VVFSFEFFPPKTEDGV NL ERMDRMVAH P+ G
Sbjct: 2 KVIEKIRDAATEE-GKVVFSFEFFPPKTEDGVDNLFERMDRMVAHGPAFCDITWGAGGST 60
Query: 181 RGM*H*ILPKRCR---IP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
+ I K + + CT+ MP EK+D AL+TIKSNG+QNVLALRGDPP
Sbjct: 61 ADLTLEISNKMQNMICVETMMHLTCTN----MPVEKIDHALDTIKSNGIQNVLALRGDPP 116
Query: 352 HGQDKFVQVEGG 387
HGQDKFVQ++GG
Sbjct: 117 HGQDKFVQIQGG 128
Score = 63.9 bits (154), Expect = 5e-09
Identities = 42/110 (38%), Positives = 54/110 (49%), Gaps = 3/110 (2%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNIRYCQKDAEYRRCGNHDAPHLHQRCLMRRWTMLSRPSSPMAS-- 319
FCDITWGAGGSTA + K + C +H C + + S
Sbjct: 49 FCDITWGAGGSTADLTLEISNK-MQNMICVE---TMMHLTCTNMPVEKIDHALDTIKSNG 104
Query: 320 -RMCLLFEVIPHMVRTNSSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
+ L P + + + FACA DLV+HIRAK+GDYFGIT+AGY
Sbjct: 105 IQNVLALRGDPPHGQDKFVQIQGGFACALDLVQHIRAKYGDYFGITVAGY 154
[6][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 127 bits (318), Expect = 5e-28
Identities = 75/132 (56%), Positives = 88/132 (66%), Gaps = 3/132 (2%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
KVIEKI +AA + +VVFSFEFFPPKTEDGV NL ERMDRMVAH P+ G
Sbjct: 2 KVIEKIRDAATEE-GKVVFSFEFFPPKTEDGVDNLFERMDRMVAHGPAFCDITWGAGGST 60
Query: 181 RGM*H*ILPKRCR---IP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
+ I K + + CT+ MP EK+D AL+TIKSNG+QNVLALRGDPP
Sbjct: 61 ADLTLEISNKMQNMICVETMMHLTCTN----MPVEKIDHALDTIKSNGIQNVLALRGDPP 116
Query: 352 HGQDKFVQVEGG 387
HGQDKFVQ++GG
Sbjct: 117 HGQDKFVQIQGG 128
Score = 63.9 bits (154), Expect = 5e-09
Identities = 42/110 (38%), Positives = 54/110 (49%), Gaps = 3/110 (2%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNIRYCQKDAEYRRCGNHDAPHLHQRCLMRRWTMLSRPSSPMAS-- 319
FCDITWGAGGSTA + K + C +H C + + S
Sbjct: 49 FCDITWGAGGSTADLTLEISNK-MQNMICVE---TMMHLTCTNMPVEKIDHALDTIKSNG 104
Query: 320 -RMCLLFEVIPHMVRTNSSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
+ L P + + + FACA DLV+HIRAK+GDYFGIT+AGY
Sbjct: 105 IQNVLALRGDPPHGQDKFVQIQGGFACALDLVQHIRAKYGDYFGITVAGY 154
[7][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 126 bits (317), Expect = 6e-28
Identities = 76/132 (57%), Positives = 86/132 (65%), Gaps = 3/132 (2%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
KVIEKI EAA + R FSFE+FPPKTE+GV NL ERMDRMVAH PS G
Sbjct: 2 KVIEKIQEAAGN--GRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGST 59
Query: 181 RGM*H*I---LPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
+ I + + + CT+ MP EK+D ALETIKSNG+QNVLALRGDPP
Sbjct: 60 ADLTLEIANRMQNMVCVETMMHLTCTN----MPVEKIDHALETIKSNGIQNVLALRGDPP 115
Query: 352 HGQDKFVQVEGG 387
HGQDKFVQVEGG
Sbjct: 116 HGQDKFVQVEGG 127
Score = 63.5 bits (153), Expect = 7e-09
Identities = 43/115 (37%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNIRY--------CQKDAEYRRCGNHDAPHLHQRCLMRRWTMLSRP 301
FCDITWGAGGSTA + C + + C N + L
Sbjct: 48 FCDITWGAGGSTADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHA--------LETI 99
Query: 302 SSPMASRMCLLFEVIPHMVRTNSSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
S + L PH + + + FACA DLV+HIRAK+GDYFGIT+AGY
Sbjct: 100 KSNGIQNVLALRGDPPHG-QDKFVQVEGGFACALDLVQHIRAKYGDYFGITVAGY 153
[8][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 125 bits (313), Expect = 2e-27
Identities = 76/132 (57%), Positives = 85/132 (64%), Gaps = 3/132 (2%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
KVIEKI EAA R FSFE+FPPKTE+GV NL ERMDRMVAH PS G
Sbjct: 2 KVIEKILEAAGD--GRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGST 59
Query: 181 RGM*H*I---LPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
+ I + + + CT+ MP EK+D ALETIKSNG+QNVLALRGDPP
Sbjct: 60 ADLTLEIANRMQNMVCVETMMHLTCTN----MPVEKIDHALETIKSNGIQNVLALRGDPP 115
Query: 352 HGQDKFVQVEGG 387
HGQDKFVQVEGG
Sbjct: 116 HGQDKFVQVEGG 127
Score = 63.5 bits (153), Expect = 7e-09
Identities = 43/115 (37%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNIRY--------CQKDAEYRRCGNHDAPHLHQRCLMRRWTMLSRP 301
FCDITWGAGGSTA + C + + C N + L
Sbjct: 48 FCDITWGAGGSTADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHA--------LETI 99
Query: 302 SSPMASRMCLLFEVIPHMVRTNSSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
S + L PH + + + FACA DLV+HIRAK+GDYFGIT+AGY
Sbjct: 100 KSNGIQNVLALRGDPPHG-QDKFVQVEGGFACALDLVQHIRAKYGDYFGITVAGY 153
[9][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 124 bits (312), Expect = 2e-27
Identities = 75/132 (56%), Positives = 86/132 (65%), Gaps = 3/132 (2%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
KVIEKI EAAA R VFSFE+FPPKTE+G+ NL ERMDRMVAH P+ G
Sbjct: 2 KVIEKIQEAAAD--GRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGST 59
Query: 181 RGM*H*I---LPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
+ I + + + CT+ MP EK+DDAL TIKSNG+QNVLALRGDPP
Sbjct: 60 ADLTLEIANRMQNMVCVETMMHLTCTN----MPVEKIDDALTTIKSNGIQNVLALRGDPP 115
Query: 352 HGQDKFVQVEGG 387
HGQDKFVQV GG
Sbjct: 116 HGQDKFVQVAGG 127
Score = 63.2 bits (152), Expect = 9e-09
Identities = 43/115 (37%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNIRY--------CQKDAEYRRCGNHDAPHLHQRCLMRRWTMLSRP 301
FCDITWGAGGSTA + C + + C N + L+
Sbjct: 48 FCDITWGAGGSTADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDA--------LTTI 99
Query: 302 SSPMASRMCLLFEVIPHMVRTNSSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
S + L PH + + FACA DLV+HIRAK+GDYFGIT+AGY
Sbjct: 100 KSNGIQNVLALRGDPPHG-QDKFVQVAGGFACALDLVQHIRAKYGDYFGITVAGY 153
[10][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 124 bits (312), Expect = 2e-27
Identities = 75/132 (56%), Positives = 86/132 (65%), Gaps = 3/132 (2%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
KVIEKI EAAA R VFSFE+FPPKTE+G+ NL ERMDRMVAH P+ G
Sbjct: 2 KVIEKIQEAAAD--GRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGST 59
Query: 181 RGM*H*I---LPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
+ I + + + CT+ MP EK+DDAL TIKSNG+QNVLALRGDPP
Sbjct: 60 ADLTLEIANRMQNMVCVETMMHLTCTN----MPVEKIDDALTTIKSNGIQNVLALRGDPP 115
Query: 352 HGQDKFVQVEGG 387
HGQDKFVQV GG
Sbjct: 116 HGQDKFVQVAGG 127
Score = 63.2 bits (152), Expect = 9e-09
Identities = 43/115 (37%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNIRY--------CQKDAEYRRCGNHDAPHLHQRCLMRRWTMLSRP 301
FCDITWGAGGSTA + C + + C N + L+
Sbjct: 48 FCDITWGAGGSTADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDA--------LTTI 99
Query: 302 SSPMASRMCLLFEVIPHMVRTNSSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
S + L PH + + FACA DLV+HIRAK+GDYFGIT+AGY
Sbjct: 100 KSNGIQNVLALRGDPPHG-QDKFVQVAGGFACALDLVQHIRAKYGDYFGITVAGY 153
[11][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 120 bits (301), Expect = 5e-26
Identities = 73/132 (55%), Positives = 84/132 (63%), Gaps = 3/132 (2%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
KVI+KI A D + FSFEFFPPKTEDGV NL ERMDRMVA+ P+ G
Sbjct: 2 KVIDKIQSLA--DEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGST 59
Query: 181 RGM*H*ILPKRCRIP*VWKP*---CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
+ I + + V CT+ MP EK+D ALETI+SNG+QNVLALRGDPP
Sbjct: 60 ADLTLDIASRMQNVVCVESMMHLTCTN----MPVEKIDHALETIRSNGIQNVLALRGDPP 115
Query: 352 HGQDKFVQVEGG 387
HGQDKFVQVEGG
Sbjct: 116 HGQDKFVQVEGG 127
Score = 58.9 bits (141), Expect = 2e-07
Identities = 40/115 (34%), Positives = 55/115 (47%), Gaps = 8/115 (6%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNIRY--------CQKDAEYRRCGNHDAPHLHQRCLMRRWTMLSRP 301
FCDITWGAGGSTA + C + + C N + R
Sbjct: 48 FCDITWGAGGSTADLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIR------- 100
Query: 302 SSPMASRMCLLFEVIPHMVRTNSSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
S+ + + + L + P + + + F CA DLV HIR+K+GDYFGIT+AGY
Sbjct: 101 SNGIQNVLALRGD--PPHGQDKFVQVEGGFDCALDLVNHIRSKYGDYFGITVAGY 153
[12][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 119 bits (297), Expect = 1e-25
Identities = 71/124 (57%), Positives = 83/124 (66%), Gaps = 4/124 (3%)
Frame = +1
Query: 28 AASDPN-RVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*IL 204
A SD N +VVFSFEFFPPKTEDGV NL +RMDRMV+H+P+ G + I
Sbjct: 23 AISDSNDKVVFSFEFFPPKTEDGVDNLFDRMDRMVSHNPTFCDITWGAGGSTADLTLDIA 82
Query: 205 PKRCR---IP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQ 375
K + + CT+ MP EK+D AL+TIKSNG+QNVLALRGDPPHGQDKFVQ
Sbjct: 83 NKMQNMICVETMMHLTCTN----MPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQ 138
Query: 376 VEGG 387
VEGG
Sbjct: 139 VEGG 142
Score = 63.9 bits (154), Expect = 5e-09
Identities = 42/110 (38%), Positives = 54/110 (49%), Gaps = 3/110 (2%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNIRYCQKDAEYRRCGNHDAPHLHQRCLMRRWTMLSRPSSPMAS-- 319
FCDITWGAGGSTA + K + C +H C + + S
Sbjct: 63 FCDITWGAGGSTADLTLDIANK-MQNMICVE---TMMHLTCTNMPVEKIDHALQTIKSNG 118
Query: 320 -RMCLLFEVIPHMVRTNSSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
+ L P + + + FACA DLVKHIR+K+GDYFGIT+AGY
Sbjct: 119 IQNVLALRGDPPHGQDKFVQVEGGFACALDLVKHIRSKYGDYFGITVAGY 168
[13][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 119 bits (297), Expect = 1e-25
Identities = 73/132 (55%), Positives = 83/132 (62%), Gaps = 3/132 (2%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
KVIEKI A +VVFSFEFFPPKTE+GV NL +RMDRMV H PS G
Sbjct: 2 KVIEKIQNAEKE--GKVVFSFEFFPPKTEEGVENLFDRMDRMVEHQPSFCDITWGAGGST 59
Query: 181 RGM*H*ILPKRCR---IP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
+ I K + + CT+ MP EK+D AL TIK+NG+QNVLALRGDPP
Sbjct: 60 ADLTLDISNKMQNMICVESMMHLTCTN----MPVEKIDHALATIKANGIQNVLALRGDPP 115
Query: 352 HGQDKFVQVEGG 387
HGQDKFVQVEGG
Sbjct: 116 HGQDKFVQVEGG 127
Score = 63.2 bits (152), Expect = 9e-09
Identities = 42/115 (36%), Positives = 55/115 (47%), Gaps = 8/115 (6%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNI--------RYCQKDAEYRRCGNHDAPHLHQRCLMRRWTMLSRP 301
FCDITWGAGGSTA + C + + C N + L+
Sbjct: 48 FCDITWGAGGSTADLTLDISNKMQNMICVESMMHLTCTNMPVEKIDHA--------LATI 99
Query: 302 SSPMASRMCLLFEVIPHMVRTNSSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
+ + L PH + + + FACA DLVKHIR+K+GDYFGIT+AGY
Sbjct: 100 KANGIQNVLALRGDPPHG-QDKFVQVEGGFACALDLVKHIRSKYGDYFGITVAGY 153
[14][TOP]
>UniRef100_Q3EAG8 Methylenetetrahydrofolate reductase n=1 Tax=Arabidopsis thaliana
RepID=Q3EAG8_ARATH
Length = 407
Score = 115 bits (287), Expect = 2e-24
Identities = 66/129 (51%), Positives = 83/129 (64%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
KV++KI + ++ + FSFEFFPPKTEDGV NL ERMDR+V++ P+ G
Sbjct: 2 KVVDKIK--SVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGST 59
Query: 181 RGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQ 360
+ I + + V + MP EK+D ALETI+SNG+QNVLALRGDPPHGQ
Sbjct: 60 ADLTLEIASRMQNVICV-ETMMHLTCTNMPIEKIDHALETIRSNGIQNVLALRGDPPHGQ 118
Query: 361 DKFVQVEGG 387
DKFVQVEGG
Sbjct: 119 DKFVQVEGG 127
Score = 61.2 bits (147), Expect = 3e-08
Identities = 41/115 (35%), Positives = 56/115 (48%), Gaps = 8/115 (6%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNIRY--------CQKDAEYRRCGNHDAPHLHQRCLMRRWTMLSRP 301
FCDITWGAGGSTA + C + + C N + R
Sbjct: 48 FCDITWGAGGSTADLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIR------- 100
Query: 302 SSPMASRMCLLFEVIPHMVRTNSSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
S+ + + + L + P + + + FACA DLV HIR+K+GDYFGIT+AGY
Sbjct: 101 SNGIQNVLALRGD--PPHGQDKFVQVEGGFACALDLVNHIRSKYGDYFGITVAGY 153
[15][TOP]
>UniRef100_Q9SE60-2 Isoform 2 of Methylenetetrahydrofolate reductase 1 n=1
Tax=Arabidopsis thaliana RepID=Q9SE60-2
Length = 421
Score = 115 bits (287), Expect = 2e-24
Identities = 66/129 (51%), Positives = 83/129 (64%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
KV++KI + ++ + FSFEFFPPKTEDGV NL ERMDR+V++ P+ G
Sbjct: 2 KVVDKIK--SVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGST 59
Query: 181 RGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQ 360
+ I + + V + MP EK+D ALETI+SNG+QNVLALRGDPPHGQ
Sbjct: 60 ADLTLEIASRMQNVICV-ETMMHLTCTNMPIEKIDHALETIRSNGIQNVLALRGDPPHGQ 118
Query: 361 DKFVQVEGG 387
DKFVQVEGG
Sbjct: 119 DKFVQVEGG 127
Score = 61.2 bits (147), Expect = 3e-08
Identities = 41/115 (35%), Positives = 56/115 (48%), Gaps = 8/115 (6%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNIRY--------CQKDAEYRRCGNHDAPHLHQRCLMRRWTMLSRP 301
FCDITWGAGGSTA + C + + C N + R
Sbjct: 48 FCDITWGAGGSTADLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIR------- 100
Query: 302 SSPMASRMCLLFEVIPHMVRTNSSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
S+ + + + L + P + + + FACA DLV HIR+K+GDYFGIT+AGY
Sbjct: 101 SNGIQNVLALRGD--PPHGQDKFVQVEGGFACALDLVNHIRSKYGDYFGITVAGY 153
[16][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 115 bits (287), Expect = 2e-24
Identities = 66/129 (51%), Positives = 83/129 (64%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
KV++KI + ++ + FSFEFFPPKTEDGV NL ERMDR+V++ P+ G
Sbjct: 2 KVVDKIK--SVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGST 59
Query: 181 RGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQ 360
+ I + + V + MP EK+D ALETI+SNG+QNVLALRGDPPHGQ
Sbjct: 60 ADLTLEIASRMQNVICV-ETMMHLTCTNMPIEKIDHALETIRSNGIQNVLALRGDPPHGQ 118
Query: 361 DKFVQVEGG 387
DKFVQVEGG
Sbjct: 119 DKFVQVEGG 127
Score = 61.2 bits (147), Expect = 3e-08
Identities = 41/115 (35%), Positives = 56/115 (48%), Gaps = 8/115 (6%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNIRY--------CQKDAEYRRCGNHDAPHLHQRCLMRRWTMLSRP 301
FCDITWGAGGSTA + C + + C N + R
Sbjct: 48 FCDITWGAGGSTADLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIR------- 100
Query: 302 SSPMASRMCLLFEVIPHMVRTNSSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
S+ + + + L + P + + + FACA DLV HIR+K+GDYFGIT+AGY
Sbjct: 101 SNGIQNVLALRGD--PPHGQDKFVQVEGGFACALDLVNHIRSKYGDYFGITVAGY 153
[17][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 108 bits (270), Expect = 2e-22
Identities = 65/132 (49%), Positives = 81/132 (61%), Gaps = 3/132 (2%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
KVI+KI+ A VVFSFEFFPPKTE+GV NL +RMDRMV H P+ G
Sbjct: 2 KVIDKINNGLAG--GNVVFSFEFFPPKTEEGVENLFDRMDRMVMHQPAFCDITWGAGGST 59
Query: 181 RGM*H*ILPKRCR---IP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
+ I K + + CT+ M E +D AL+++KSNG+QN+LALRGDPP
Sbjct: 60 SAVTLDIANKMQNMICVETMMHLTCTN----MLVETLDGALDSVKSNGIQNILALRGDPP 115
Query: 352 HGQDKFVQVEGG 387
HGQDKFV +EGG
Sbjct: 116 HGQDKFVTIEGG 127
Score = 63.2 bits (152), Expect = 9e-09
Identities = 42/110 (38%), Positives = 54/110 (49%), Gaps = 3/110 (2%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNIRYCQKDAEYRRCGNHDAPHLHQRCLMRRWTMLSRPSSPMAS-- 319
FCDITWGAGGST+A + K + C +H C L + S
Sbjct: 48 FCDITWGAGGSTSAVTLDIANK-MQNMICVE---TMMHLTCTNMLVETLDGALDSVKSNG 103
Query: 320 -RMCLLFEVIPHMVRTNSSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
+ L P + + F+CA DLV+HIRAK+GDYFGIT+AGY
Sbjct: 104 IQNILALRGDPPHGQDKFVTIEGGFSCALDLVRHIRAKYGDYFGITVAGY 153
[18][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 107 bits (268), Expect = 3e-22
Identities = 64/132 (48%), Positives = 81/132 (61%), Gaps = 3/132 (2%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
KVI+KI+ A VVFSFEFFPPKTE+GV NL +RMDRMV H P+ G
Sbjct: 2 KVIDKINNGLAG--GNVVFSFEFFPPKTEEGVENLFDRMDRMVRHQPAFCDITWGAGGST 59
Query: 181 RGM*H*ILPKRCR---IP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
+ I K + + CT+ M E +D+AL+ +KSNG+QN+LALRGDPP
Sbjct: 60 SAITLDIANKMQNMICVETMMHLTCTN----MLVETLDNALDNVKSNGIQNILALRGDPP 115
Query: 352 HGQDKFVQVEGG 387
HGQDKFV ++GG
Sbjct: 116 HGQDKFVTIDGG 127
Score = 59.3 bits (142), Expect = 1e-07
Identities = 40/110 (36%), Positives = 52/110 (47%), Gaps = 3/110 (2%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNIRYCQKDAEYRRCGNHDAPHLHQRCLMRRWTMLSRPSSPMAS-- 319
FCDITWGAGGST+A + K + C +H C L + S
Sbjct: 48 FCDITWGAGGSTSAITLDIANK-MQNMICVE---TMMHLTCTNMLVETLDNALDNVKSNG 103
Query: 320 -RMCLLFEVIPHMVRTNSSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
+ L P + F+CA DLV+HI+ K+GDYFGIT+AGY
Sbjct: 104 IQNILALRGDPPHGQDKFVTIDGGFSCALDLVRHIKDKYGDYFGITVAGY 153
[19][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 90.1 bits (222), Expect = 7e-17
Identities = 54/107 (50%), Positives = 66/107 (61%), Gaps = 3/107 (2%)
Frame = +1
Query: 76 PKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*I---LPKRCRIP*VWKP*C 246
P+ +GV NL ERMDRMVAH P+ G + I + + + C
Sbjct: 13 PRRREGVENLFERMDRMVAHGPNFCDITWGAGGSTADVTLDIANRMQNMVCVETMMHLTC 72
Query: 247 TSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
T+ MP EK+D+AL+TIKSNG+QNVLALRGDPPHGQDKFVQV GG
Sbjct: 73 TN----MPVEKIDNALDTIKSNGIQNVLALRGDPPHGQDKFVQVAGG 115
Score = 60.1 bits (144), Expect = 7e-08
Identities = 41/115 (35%), Positives = 53/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNI--------RYCQKDAEYRRCGNHDAPHLHQRCLMRRWTMLSRP 301
FCDITWGAGGSTA + C + + C N + L
Sbjct: 36 FCDITWGAGGSTADVTLDIANRMQNMVCVETMMHLTCTNMPVEKIDNA--------LDTI 87
Query: 302 SSPMASRMCLLFEVIPHMVRTNSSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
S + L PH + + F+CA DLV+HI+AK+GDYFGIT+AGY
Sbjct: 88 KSNGIQNVLALRGDPPHG-QDKFVQVAGGFSCALDLVEHIKAKYGDYFGITVAGY 141
[20][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 64.7 bits (156), Expect(2) = 6e-15
Identities = 44/133 (33%), Positives = 68/133 (51%), Gaps = 4/133 (3%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
K+ +K+ + P++ FSFE+F PKT GV NL +RMDRM + S+ + W
Sbjct: 2 KITQKLADRHKEKPDKATFSFEYFVPKTTQGVQNLYDRMDRM--YEASLPEFIDITWNAG 59
Query: 181 RGM*H*I---LPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
G + L + + MP ++D+ALE ++G QN+LALRGDPP
Sbjct: 60 GGRLSQLSTELVATAQSVLGLETCMHLTCTNMPISQIDEALEDAYNSGCQNILALRGDPP 119
Query: 352 -HGQDKFVQVEGG 387
+ + + +EGG
Sbjct: 120 LNAPNGWQPIEGG 132
Score = 39.3 bits (90), Expect(2) = 6e-15
Identities = 17/26 (65%), Positives = 22/26 (84%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A+DLVK+IRAK+GD+F I +AGY
Sbjct: 133 FNYAKDLVKYIRAKYGDHFDIGVAGY 158
[21][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 79.0 bits (193), Expect = 2e-13
Identities = 51/133 (38%), Positives = 69/133 (51%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
K+I K+ E FSFEFFPP+TE+GV NL ER+DRMVA+ P G
Sbjct: 2 KLIHKVEEKMKK--GETFFSFEFFPPRTEEGVENLFERLDRMVAYGPVFCDITWGAGGST 59
Query: 181 RGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQ 360
+ I + + V + MP+EK++ AL +K G+QN+LALRGDPP
Sbjct: 60 ADVTLDIATRMQNLICV-ETMMHLTCTNMPEEKLESALHEVKKMGVQNILALRGDPP--- 115
Query: 361 DKFVQVEGGLCLC 399
+V G C+C
Sbjct: 116 ----KVRVGACVC 124
[22][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 77.4 bits (189), Expect = 4e-13
Identities = 48/129 (37%), Positives = 74/129 (57%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
K+ +KI ++A +D ++ +SFE+FPP+T G+ NLL+R++RM A P +
Sbjct: 2 KITQKIQQSANND--KIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRT 59
Query: 181 RGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQ 360
+ ++ K C+ + MP EK+D AL K +G +NVLALRGDPP G+
Sbjct: 60 SDLTSEMV-KTCQGLIGMETCMHLTCTNMPKEKVDIALREAKQHGCRNVLALRGDPPSGK 118
Query: 361 DKFVQVEGG 387
D++ VEGG
Sbjct: 119 DEWEAVEGG 127
[23][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 74.7 bits (182), Expect = 3e-12
Identities = 54/136 (39%), Positives = 69/136 (50%), Gaps = 9/136 (6%)
Frame = +1
Query: 10 EKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVG-------- 165
EK+ + A++ RV SFEFFPPKT GV NL +RMDRM A PS + G
Sbjct: 5 EKLAQNEAAE--RVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLSDL 62
Query: 166 -CWRINRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRG 342
C +N L + CT MP EK+D AL+ +G N+LALRG
Sbjct: 63 TCEMVNVAQSVYGLETCMHLT------CTD----MPTEKVDAALQAAYKSGCTNILALRG 112
Query: 343 DPPHGQDKFVQVEGGL 390
DPP ++K+ EGGL
Sbjct: 113 DPPREKEKWEAAEGGL 128
[24][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 71.6 bits (174), Expect = 2e-11
Identities = 48/132 (36%), Positives = 73/132 (55%), Gaps = 3/132 (2%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
K+I+KI + S N +SFE+FPPKT +GV NL +R+ RM+ P + G
Sbjct: 5 KIIDKIQKKKES--NTPFYSFEYFPPKTMEGVQNLYDRLGRMLLFEPLFIDITWGAGGST 62
Query: 181 RGM*H*ILPKR---CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
+ I K C + + CT+ MP ++ AL+ KS G++N+LALRGDPP
Sbjct: 63 SALTLEIAEKAQNVCGLETMMHLTCTN----MPVSEIIYALDKAKSTGIRNILALRGDPP 118
Query: 352 HGQDKFVQVEGG 387
G++ + ++EGG
Sbjct: 119 RGEE-WKKIEGG 129
[25][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 52.4 bits (124), Expect(2) = 6e-11
Identities = 38/112 (33%), Positives = 56/112 (50%), Gaps = 3/112 (2%)
Frame = +1
Query: 25 AAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*Y-YVGCWRINRGM*H*I 201
AA + + FSFEFF PKT GV NL +RMDRM P + + R+++ +
Sbjct: 13 AADEEQPKASFSFEFFVPKTLQGVQNLYDRMDRMYQTQPEFIDITWNAGGRLSQRTSELV 72
Query: 202 LPKR--CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
+ + CT+ + + DE ++ A E G +N+LALRGDPP
Sbjct: 73 ATSQGVLGLETCMHLTCTNMSTALVDEALERAYEA----GCENILALRGDPP 120
Score = 38.1 bits (87), Expect(2) = 6e-11
Identities = 15/26 (57%), Positives = 21/26 (80%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A+DLV HIRA++GD+F + +AGY
Sbjct: 132 FRYAKDLVAHIRARYGDHFDVGVAGY 157
[26][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 70.1 bits (170), Expect = 7e-11
Identities = 49/130 (37%), Positives = 62/130 (47%), Gaps = 9/130 (6%)
Frame = +1
Query: 25 AAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVG---------CWRI 177
A A R SFEFFPPKT GV NL +RMDRM + PS + G C +
Sbjct: 8 AHAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLSELTCEMV 67
Query: 178 NRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHG 357
N + + CT MP EK+D AL++ G N+LALRGDPP
Sbjct: 68 N------VAQSVYGLETCMHLTCTD----MPREKVDTALQSAFKAGCTNILALRGDPPRE 117
Query: 358 QDKFVQVEGG 387
++K+ EGG
Sbjct: 118 KEKWEATEGG 127
[27][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 70.1 bits (170), Expect = 7e-11
Identities = 49/130 (37%), Positives = 62/130 (47%), Gaps = 9/130 (6%)
Frame = +1
Query: 25 AAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVG---------CWRI 177
A A R SFEFFPPKT GV NL +RMDRM + PS + G C +
Sbjct: 8 AHAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLSELTCEMV 67
Query: 178 NRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHG 357
N + + CT MP EK+D AL++ G N+LALRGDPP
Sbjct: 68 N------VAQSVYGLETCMHLTCTD----MPREKVDTALQSAFKAGCTNILALRGDPPRE 117
Query: 358 QDKFVQVEGG 387
++K+ EGG
Sbjct: 118 KEKWEATEGG 127
[28][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 70.1 bits (170), Expect = 7e-11
Identities = 49/125 (39%), Positives = 62/125 (49%), Gaps = 4/125 (3%)
Frame = +1
Query: 25 AAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCW----RINRGM* 192
A A R SFEFFPPKT GV NL +RMDRM PS + G + M
Sbjct: 8 ALAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLAELTCEMV 67
Query: 193 H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFV 372
H + + CT MP EK+D+AL++ G N+LALRGDPP ++ +
Sbjct: 68 H-VAQSVYGLETCMHLTCTD----MPREKVDEALQSAFKAGCTNILALRGDPPREKESWE 122
Query: 373 QVEGG 387
Q EGG
Sbjct: 123 QTEGG 127
[29][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 70.1 bits (170), Expect = 7e-11
Identities = 48/130 (36%), Positives = 63/130 (48%), Gaps = 9/130 (6%)
Frame = +1
Query: 25 AAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVG---------CWRI 177
A A R SFEFFPPKT GV NL +RMDRM + PS + G C +
Sbjct: 8 AHAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLSELTCEMV 67
Query: 178 NRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHG 357
N + + CT MP EK+D A+++ G N+LALRGDPP
Sbjct: 68 N------VAQSVYGLETCMHLTCTD----MPREKVDAAIQSAFKAGCTNILALRGDPPRE 117
Query: 358 QDKFVQVEGG 387
++K+ +EGG
Sbjct: 118 KEKWEAIEGG 127
[30][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 70.1 bits (170), Expect = 7e-11
Identities = 48/130 (36%), Positives = 63/130 (48%), Gaps = 9/130 (6%)
Frame = +1
Query: 25 AAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVG---------CWRI 177
A A R SFEFFPPKT GV NL +RMDRM + PS + G C +
Sbjct: 8 AHAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLSELTCEMV 67
Query: 178 NRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHG 357
N + + CT MP EK+D A+++ G N+LALRGDPP
Sbjct: 68 N------VAQSVYGLETCMHLTCTD----MPREKVDAAIQSAFKAGCTNILALRGDPPRE 117
Query: 358 QDKFVQVEGG 387
++K+ +EGG
Sbjct: 118 KEKWEAIEGG 127
[31][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 69.3 bits (168), Expect = 1e-10
Identities = 47/119 (39%), Positives = 59/119 (49%), Gaps = 9/119 (7%)
Frame = +1
Query: 58 SFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVG---------CWRINRGM*H*ILPK 210
SFEFFPPKT GV NL +RMDRM + PS + G C +N L
Sbjct: 19 SFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLSELTCEMVNVAQSVYGLET 78
Query: 211 RCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
+ CT MP EK+D AL++ G N+LALRGDPP ++K+ EGG
Sbjct: 79 CMHLT------CTD----MPSEKVDAALQSAFKAGCTNILALRGDPPREKEKWEATEGG 127
[32][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 69.3 bits (168), Expect = 1e-10
Identities = 47/119 (39%), Positives = 59/119 (49%), Gaps = 9/119 (7%)
Frame = +1
Query: 58 SFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVG---------CWRINRGM*H*ILPK 210
SFEFFPPKT GV NL +RMDRM + PS + G C +N L
Sbjct: 19 SFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLSELTCEMVNVAQSVYGLET 78
Query: 211 RCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
+ CT MP EK+D AL++ G N+LALRGDPP ++K+ EGG
Sbjct: 79 CMHLT------CTD----MPSEKVDAALQSAFKAGCTNILALRGDPPREKEKWEATEGG 127
[33][TOP]
>UniRef100_A9UZU5 Methylenetetrahydrofolate reductase n=1 Tax=Monosiga brevicollis
RepID=A9UZU5_MONBE
Length = 332
Score = 68.9 bits (167), Expect = 2e-10
Identities = 45/132 (34%), Positives = 70/132 (53%), Gaps = 3/132 (2%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
K+ +++ E +A V SFEFFPP+T+DGV +L+ R+ R P + G
Sbjct: 5 KISDRLQELSAKGEKFV--SFEFFPPRTDDGVTSLMSRIQRYNDQQPLFMDMTWGAGGST 62
Query: 181 RGM*H*I---LPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
+ + + K C CT+ MP EK+D AL+ + G++N++ALRGDPP
Sbjct: 63 SDLTLDLCTRMVKECGANANMHLTCTN----MPSEKIDIALKGARDAGIRNIVALRGDPP 118
Query: 352 HGQDKFVQVEGG 387
G++ + VEGG
Sbjct: 119 AGEEAWEAVEGG 130
Score = 55.1 bits (131), Expect = 2e-06
Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 3/110 (2%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNIRYCQKDAEYRRCGNHDAPHLHQRCL---MRRWTMLSRPSSPMA 316
F D+TWGAGGST+ + C + + CG + ++H C + + + +
Sbjct: 51 FMDMTWGAGGSTSDLTLDLCTRMV--KECGAN--ANMHLTCTNMPSEKIDIALKGARDAG 106
Query: 317 SRMCLLFEVIPHMVRTNSSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
R + P + ++CA DLVKHIR +HGD+F I ++GY
Sbjct: 107 IRNIVALRGDPPAGEEAWEAVEGGYSCALDLVKHIRKEHGDFFSIAVSGY 156
[34][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 68.6 bits (166), Expect = 2e-10
Identities = 47/119 (39%), Positives = 59/119 (49%), Gaps = 9/119 (7%)
Frame = +1
Query: 58 SFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVG---------CWRINRGM*H*ILPK 210
SFEFFPPKT GV NL +RMDRM + PS + G C +N L
Sbjct: 19 SFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLSELTCEMVNVAQSVYGLET 78
Query: 211 RCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
+ CT MP EK+D AL++ G N+LALRGDPP ++K+ EGG
Sbjct: 79 CMHLT------CTD----MPREKVDAALQSAFKAGCTNILALRGDPPREKEKWEATEGG 127
[35][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 68.2 bits (165), Expect = 3e-10
Identities = 49/135 (36%), Positives = 71/135 (52%), Gaps = 6/135 (4%)
Frame = +1
Query: 1 KVIEKI--HEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGC-W 171
++ EK+ H + ++ P FSFE+F PKT GV NL +RMDRM S L ++ W
Sbjct: 2 RISEKLQNHRSKSTKPT---FSFEYFVPKTTQGVQNLYDRMDRMYQ---STLPQFIDVTW 55
Query: 172 RINRGM*H*I---LPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRG 342
G+ + L + + + MP ++DDALE+ + +G QN+LALRG
Sbjct: 56 NAGGGVLSQLTTDLVETSQSVLGLETCMHLTCTNMPVSQIDDALESARLSGCQNILALRG 115
Query: 343 DPPHGQDKFVQVEGG 387
DPP D + VEGG
Sbjct: 116 DPPVNSDSWQPVEGG 130
[36][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 53.9 bits (128), Expect(2) = 3e-10
Identities = 24/41 (58%), Positives = 32/41 (78%)
Frame = +1
Query: 265 MPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
MP EK+D AL+ K +G +N+LALRGDPP G+D++ VEGG
Sbjct: 47 MPREKVDTALKEAKEHGCRNILALRGDPPMGKDEWEAVEGG 87
Score = 34.3 bits (77), Expect(2) = 3e-10
Identities = 13/25 (52%), Positives = 18/25 (72%)
Frame = +3
Query: 189 VTLDIAKKMQNTVGVETMMHLTCTN 263
+T ++ K Q +G+ET MHLTCTN
Sbjct: 22 LTSEMVKTCQGLIGIETCMHLTCTN 46
[37][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 67.8 bits (164), Expect = 4e-10
Identities = 51/138 (36%), Positives = 66/138 (47%), Gaps = 9/138 (6%)
Frame = +1
Query: 4 VIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVG------ 165
V +K+++ A +V SFEFFPPKT GV NL +RMDRM A PS + G
Sbjct: 3 VKDKLYQNEAG--GQVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS 60
Query: 166 ---CWRINRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLAL 336
C +N + + CT MP EK+D AL G N+LAL
Sbjct: 61 DLTCEMVN------VAQSVYGLETCMHLTCTD----MPLEKVDAALSAAYKAGCTNILAL 110
Query: 337 RGDPPHGQDKFVQVEGGL 390
RGDPP ++ + EGGL
Sbjct: 111 RGDPPRDKEAWEATEGGL 128
[38][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 50.1 bits (118), Expect(2) = 5e-10
Identities = 40/123 (32%), Positives = 56/123 (45%), Gaps = 7/123 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T +G VNL+ R DRM A P V + G ++ ++
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 159
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGLC 393
C + + C P E++ L K GL+N++ALRGDP D + EGG
Sbjct: 160 CGLETILHMTCCQQRP----EEITGHLHRAKQLGLKNIMALRGDPV--GDHWEAEEGGFS 213
Query: 394 LCT 402
T
Sbjct: 214 YAT 216
Score = 37.4 bits (85), Expect(2) = 5e-10
Identities = 16/26 (61%), Positives = 19/26 (73%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F+ A DLVKHIR + DYF I +AGY
Sbjct: 212 FSYATDLVKHIRTEFADYFDICVAGY 237
[39][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 50.1 bits (118), Expect(2) = 5e-10
Identities = 40/123 (32%), Positives = 56/123 (45%), Gaps = 7/123 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T +G VNL+ R DRM A P V + G ++ ++
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 159
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGLC 393
C + + C P E++ L K GL+N++ALRGDP D + EGG
Sbjct: 160 CGLETILHMTCCQQRP----EEITGHLHRAKQLGLKNIMALRGDPV--GDHWEAEEGGFS 213
Query: 394 LCT 402
T
Sbjct: 214 YAT 216
Score = 37.4 bits (85), Expect(2) = 5e-10
Identities = 16/26 (61%), Positives = 19/26 (73%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F+ A DLVKHIR + DYF I +AGY
Sbjct: 212 FSYATDLVKHIRTEFADYFDICVAGY 237
[40][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 50.1 bits (118), Expect(2) = 5e-10
Identities = 40/123 (32%), Positives = 56/123 (45%), Gaps = 7/123 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T +G VNL+ R DRM A P V + G ++ ++
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 159
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGLC 393
C + + C P E++ L K GL+N++ALRGDP D + EGG
Sbjct: 160 CGLETILHMTCCQQRP----EEITGHLHRAKQLGLKNIMALRGDPV--GDHWEAEEGGFS 213
Query: 394 LCT 402
T
Sbjct: 214 YAT 216
Score = 37.4 bits (85), Expect(2) = 5e-10
Identities = 16/26 (61%), Positives = 19/26 (73%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F+ A DLVKHIR + DYF I +AGY
Sbjct: 212 FSYATDLVKHIRTEFADYFDICVAGY 237
[41][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 50.1 bits (118), Expect(2) = 5e-10
Identities = 40/123 (32%), Positives = 56/123 (45%), Gaps = 7/123 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T +G VNL+ R DRM A P V + G ++ ++
Sbjct: 59 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGLC 393
C + + C P E++ L K GL+N++ALRGDP D + EGG
Sbjct: 119 CGLETILHMTCCQQRP----EEITGHLHRAKQLGLKNIMALRGDPV--GDHWEAEEGGFS 172
Query: 394 LCT 402
T
Sbjct: 173 YAT 175
Score = 37.4 bits (85), Expect(2) = 5e-10
Identities = 16/26 (61%), Positives = 19/26 (73%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F+ A DLVKHIR + DYF I +AGY
Sbjct: 171 FSYATDLVKHIRTEFADYFDICVAGY 196
[42][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 67.4 bits (163), Expect = 5e-10
Identities = 50/137 (36%), Positives = 67/137 (48%), Gaps = 9/137 (6%)
Frame = +1
Query: 4 VIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVG------ 165
+ EK+ + A+ R SFEFFPPKT GV NL +RMDRM A PS + G
Sbjct: 3 ISEKLAQNEAA--GRPGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS 60
Query: 166 ---CWRINRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLAL 336
C +N + + CT MP EK+D AL++ G N+LAL
Sbjct: 61 DLTCEMVN------VAQSVYGLETCMHLTCTD----MPLEKVDAALQSAYKAGCTNILAL 110
Query: 337 RGDPPHGQDKFVQVEGG 387
RGDPP ++K+ +GG
Sbjct: 111 RGDPPREKEKWEATDGG 127
[43][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 67.0 bits (162), Expect = 6e-10
Identities = 49/136 (36%), Positives = 66/136 (48%), Gaps = 10/136 (7%)
Frame = +1
Query: 10 EKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM 189
+K+ E AA+ R SFE+FPPKT GV NL +RMDRM P+ + G +
Sbjct: 5 QKLQEQAAT--GRPGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGSRSEL 62
Query: 190 *H*ILPKRCRIP*VWKP*----------CTSPAPTMPDEKMDDALETIKSNGLQNVLALR 339
C + + + CT MP E++D ALE + G N+LALR
Sbjct: 63 -------TCEMVRIAQTVFGLETCMHLTCTD----MPRERVDAALEAAYNAGCTNILALR 111
Query: 340 GDPPHGQDKFVQVEGG 387
GDPP Q+K+ EGG
Sbjct: 112 GDPPREQEKWEAAEGG 127
[44][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 67.0 bits (162), Expect = 6e-10
Identities = 49/135 (36%), Positives = 64/135 (47%), Gaps = 9/135 (6%)
Frame = +1
Query: 10 EKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVG-------- 165
EK+ + A+ R SFEFFPPKT GV NL +RMDRM A PS + G
Sbjct: 5 EKLAQNEAA--GRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLSDL 62
Query: 166 -CWRINRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRG 342
C +N + + CT MP EK+D AL+ G N+LALRG
Sbjct: 63 TCEMVN------VAQSVYGLETCMHLTCTD----MPQEKVDAALQAAYKAGCTNILALRG 112
Query: 343 DPPHGQDKFVQVEGG 387
DPP ++ + +GG
Sbjct: 113 DPPRDKEAWEAADGG 127
[45][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 47.8 bits (112), Expect(2) = 8e-10
Identities = 39/123 (31%), Positives = 55/123 (44%), Gaps = 7/123 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T +G VNL+ R DRM A P V + G ++ ++
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTALNY 159
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGLC 393
C + + C E++ L K GL+N++ALRGDP D + EGG
Sbjct: 160 CGLETILHMTCCQ----QRQEEISGHLHRAKQLGLKNIMALRGDPV--GDHWEAEEGGFS 213
Query: 394 LCT 402
T
Sbjct: 214 YAT 216
Score = 38.9 bits (89), Expect(2) = 8e-10
Identities = 17/26 (65%), Positives = 20/26 (76%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F+ A DLVKHIR + GDYF I +AGY
Sbjct: 212 FSYATDLVKHIRNEFGDYFDICVAGY 237
[46][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 47.8 bits (112), Expect(2) = 8e-10
Identities = 39/123 (31%), Positives = 55/123 (44%), Gaps = 7/123 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T +G VNL+ R DRM A P V + G ++ ++
Sbjct: 65 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTALNY 124
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGLC 393
C + + C E++ L K GL+N++ALRGDP D + EGG
Sbjct: 125 CGLETILHMTCCQ----QRQEEISGHLHRAKQLGLKNIMALRGDPV--GDHWEAEEGGFS 178
Query: 394 LCT 402
T
Sbjct: 179 YAT 181
Score = 38.9 bits (89), Expect(2) = 8e-10
Identities = 17/26 (65%), Positives = 20/26 (76%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F+ A DLVKHIR + GDYF I +AGY
Sbjct: 177 FSYATDLVKHIRNEFGDYFDICVAGY 202
[47][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 54.3 bits (129), Expect(2) = 1e-09
Identities = 40/113 (35%), Positives = 55/113 (48%), Gaps = 3/113 (2%)
Frame = +1
Query: 22 EAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*Y-YVGCWRINRGM*H* 198
+ A + FSFEFF PKT GV NL ERMDRM P + + R++
Sbjct: 8 QRAHEEREDATFSFEFFVPKTSQGVQNLYERMDRMYQTQPEFIDITWNAGGRLSMLSTDL 67
Query: 199 ILPKR--CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
+ + + CT+ MP ++DDAL+ G +N+LALRGDPP
Sbjct: 68 VATSQGVLGLETCMHLTCTN----MPVSQIDDALKKAYDAGCENILALRGDPP 116
Score = 32.0 bits (71), Expect(2) = 1e-09
Identities = 13/26 (50%), Positives = 19/26 (73%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A+DLV +IR ++GD+F I +A Y
Sbjct: 133 FRYAKDLVSYIREQYGDHFDIGVAAY 158
[48][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 66.2 bits (160), Expect = 1e-09
Identities = 50/137 (36%), Positives = 64/137 (46%), Gaps = 9/137 (6%)
Frame = +1
Query: 4 VIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVG------ 165
V EK+ + AS R SFEFFPPKT GV NL +RMDRM P+ + G
Sbjct: 3 VKEKLAHSEAS--GRPSISFEFFPPKTAQGVQNLYDRMDRMHGLGPAFIDITWGAGGRLS 60
Query: 166 ---CWRINRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLAL 336
C +N + + CT MP EK+D AL+ G N+LAL
Sbjct: 61 DLTCEMVN------VAQSVYGLETCMHLTCTD----MPREKVDWALQCAHKAGCTNILAL 110
Query: 337 RGDPPHGQDKFVQVEGG 387
RGDPP ++ + EGG
Sbjct: 111 RGDPPREKESWAPTEGG 127
[49][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 66.2 bits (160), Expect = 1e-09
Identities = 50/137 (36%), Positives = 64/137 (46%), Gaps = 9/137 (6%)
Frame = +1
Query: 4 VIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVG------ 165
V EK+ + AS R SFEFFPPKT GV NL +RMDRM P+ + G
Sbjct: 3 VKEKLAHSEAS--GRPSISFEFFPPKTAQGVQNLYDRMDRMHGLGPAFIDITWGAGGRLS 60
Query: 166 ---CWRINRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLAL 336
C +N + + CT MP EK+D AL+ G N+LAL
Sbjct: 61 DLTCEMVN------VAQSVYGLETCMHLTCTD----MPREKVDWALQCAHKAGCTNILAL 110
Query: 337 RGDPPHGQDKFVQVEGG 387
RGDPP ++ + EGG
Sbjct: 111 RGDPPREKESWAPTEGG 127
[50][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 66.2 bits (160), Expect = 1e-09
Identities = 47/121 (38%), Positives = 58/121 (47%), Gaps = 10/121 (8%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*ILPKRCRIP*VW 234
FSFEFFPPKT GV NL +RMDRM PS + I G + C + V
Sbjct: 18 FSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFI-------DITWGAGGRLAQLTCEMVGVA 70
Query: 235 KP----------*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEG 384
+ CT M EK+D+AL G N+LALRGDPP ++K+ EG
Sbjct: 71 QSQYGLETCMHLTCTD----MGKEKVDEALRNAYKAGCTNILALRGDPPREKEKWEATEG 126
Query: 385 G 387
G
Sbjct: 127 G 127
[51][TOP]
>UniRef100_A6SLU6 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6SLU6_BOTFB
Length = 390
Score = 66.2 bits (160), Expect = 1e-09
Identities = 47/121 (38%), Positives = 58/121 (47%), Gaps = 10/121 (8%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*ILPKRCRIP*VW 234
FSFEFFPPKT GV NL +RMDRM PS + I G + C + V
Sbjct: 18 FSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFI-------DITWGAGGRLAQLTCEMVGVA 70
Query: 235 KP----------*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEG 384
+ CT M EK+D+AL G N+LALRGDPP ++K+ EG
Sbjct: 71 QSQYGLETCMHLTCTD----MGKEKVDEALRNAYKAGCTNILALRGDPPREKEKWEATEG 126
Query: 385 G 387
G
Sbjct: 127 G 127
[52][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 50.4 bits (119), Expect(2) = 2e-09
Identities = 41/123 (33%), Positives = 60/123 (48%), Gaps = 7/123 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T G VNL+ R DRM + P + + G ++ ++
Sbjct: 60 FSLEFFPPRTSSGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY 119
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGLC 393
C + V C + EK+ D L K GL+N++ALRGDP G+D +V+ +GG
Sbjct: 120 CGLESVLHLTCCN----QTKEKITDHLNKAKRLGLKNIMALRGDPV-GED-WVEEDGGFN 173
Query: 394 LCT 402
T
Sbjct: 174 FAT 176
Score = 35.0 bits (79), Expect(2) = 2e-09
Identities = 16/26 (61%), Positives = 18/26 (69%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A DLVKHIR + DYF I +AGY
Sbjct: 172 FNFATDLVKHIRHEFDDYFDICVAGY 197
[53][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 65.5 bits (158), Expect = 2e-09
Identities = 47/124 (37%), Positives = 59/124 (47%), Gaps = 9/124 (7%)
Frame = +1
Query: 46 RVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVG---------CWRINRGM*H* 198
RV SFEFFPPKT GV NL +RMDRM + PS + G C +N
Sbjct: 15 RVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLSDLTCEMVN------ 68
Query: 199 ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQV 378
+ + CT MP EK++ AL G N+LALRGDPP ++ +
Sbjct: 69 VAQSVYGLETCMHLTCTD----MPLEKVNAALSAAYKAGCTNILALRGDPPRDKEAWEAT 124
Query: 379 EGGL 390
EGGL
Sbjct: 125 EGGL 128
[54][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 65.5 bits (158), Expect = 2e-09
Identities = 47/124 (37%), Positives = 59/124 (47%), Gaps = 9/124 (7%)
Frame = +1
Query: 46 RVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVG---------CWRINRGM*H* 198
RV SFEFFPPKT GV NL +RMDRM + PS + G C +N
Sbjct: 15 RVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLSDLTCEMVN------ 68
Query: 199 ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQV 378
+ + CT MP EK++ AL G N+LALRGDPP ++ +
Sbjct: 69 VAQSVYGLETCMHLTCTD----MPLEKVNAALSAAYKAGCTNILALRGDPPRDKEAWEAT 124
Query: 379 EGGL 390
EGGL
Sbjct: 125 EGGL 128
[55][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 65.5 bits (158), Expect = 2e-09
Identities = 47/124 (37%), Positives = 59/124 (47%), Gaps = 9/124 (7%)
Frame = +1
Query: 46 RVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVG---------CWRINRGM*H* 198
RV SFEFFPPKT GV NL +RMDRM + PS + G C +N
Sbjct: 15 RVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLSDLTCEMVN------ 68
Query: 199 ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQV 378
+ + CT MP EK++ AL G N+LALRGDPP ++ +
Sbjct: 69 VAQSVYGLETCMHLTCTD----MPLEKVNAALSAAYKAGCTNILALRGDPPRDKEAWEAT 124
Query: 379 EGGL 390
EGGL
Sbjct: 125 EGGL 128
[56][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 47.0 bits (110), Expect(2) = 2e-09
Identities = 39/121 (32%), Positives = 53/121 (43%), Gaps = 10/121 (8%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCW----------RINRGM*H*IL 204
FS EFFPP+T +G VNL+ R DRM A P Y W + M
Sbjct: 101 FSLEFFPPRTAEGAVNLISRFDRMAAGGPL---YIDVTWHPAGDPGSDKETSSMMIASTA 157
Query: 205 PKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEG 384
C + + C E++ L K GL+N++ALRGDP D++ + EG
Sbjct: 158 VNYCGLETILHMTCCRQRL----EEITGHLHKAKQLGLKNIMALRGDPI--GDQWEEEEG 211
Query: 385 G 387
G
Sbjct: 212 G 212
Score = 38.1 bits (87), Expect(2) = 2e-09
Identities = 17/26 (65%), Positives = 20/26 (76%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A DLVKHIR++ GDYF I +AGY
Sbjct: 213 FNYAVDLVKHIRSEFGDYFDICVAGY 238
[57][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 47.0 bits (110), Expect(2) = 2e-09
Identities = 39/121 (32%), Positives = 53/121 (43%), Gaps = 10/121 (8%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCW----------RINRGM*H*IL 204
FS EFFPP+T +G VNL+ R DRM A P Y W + M
Sbjct: 83 FSLEFFPPRTAEGAVNLISRFDRMAAGGPL---YIDVTWHPAGDPGSDKETSSMMIASTA 139
Query: 205 PKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEG 384
C + + C E++ L K GL+N++ALRGDP D++ + EG
Sbjct: 140 VNYCGLETILHMTCCRQRL----EEITGHLHKAKQLGLKNIMALRGDPI--GDQWEEEEG 193
Query: 385 G 387
G
Sbjct: 194 G 194
Score = 38.1 bits (87), Expect(2) = 2e-09
Identities = 17/26 (65%), Positives = 20/26 (76%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A DLVKHIR++ GDYF I +AGY
Sbjct: 195 FNYAVDLVKHIRSEFGDYFDICVAGY 220
[58][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 47.0 bits (110), Expect(2) = 2e-09
Identities = 39/121 (32%), Positives = 53/121 (43%), Gaps = 10/121 (8%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCW----------RINRGM*H*IL 204
FS EFFPP+T +G VNL+ R DRM A P Y W + M
Sbjct: 90 FSLEFFPPRTAEGAVNLISRFDRMAAGGPL---YIDVTWHPAGDPGSDKETSSMMIASTA 146
Query: 205 PKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEG 384
C + + C E++ L K GL+N++ALRGDP D++ + EG
Sbjct: 147 VNYCGLETILHMTCCRQRL----EEITGHLHKAKQLGLKNIMALRGDPI--GDQWEEEEG 200
Query: 385 G 387
G
Sbjct: 201 G 201
Score = 38.1 bits (87), Expect(2) = 2e-09
Identities = 17/26 (65%), Positives = 20/26 (76%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A DLVKHIR++ GDYF I +AGY
Sbjct: 202 FNYAVDLVKHIRSEFGDYFDICVAGY 227
[59][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 47.0 bits (110), Expect(2) = 2e-09
Identities = 39/121 (32%), Positives = 53/121 (43%), Gaps = 10/121 (8%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCW----------RINRGM*H*IL 204
FS EFFPP+T +G VNL+ R DRM A P Y W + M
Sbjct: 60 FSLEFFPPRTAEGAVNLISRFDRMAAGGPL---YIDVTWHPAGDPGSDKETSSMMIASTA 116
Query: 205 PKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEG 384
C + + C E++ L K GL+N++ALRGDP D++ + EG
Sbjct: 117 VNYCGLETILHMTCCRQRL----EEITGHLHKAKQLGLKNIMALRGDPI--GDQWEEEEG 170
Query: 385 G 387
G
Sbjct: 171 G 171
Score = 38.1 bits (87), Expect(2) = 2e-09
Identities = 17/26 (65%), Positives = 20/26 (76%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A DLVKHIR++ GDYF I +AGY
Sbjct: 172 FNYAVDLVKHIRSEFGDYFDICVAGY 197
[60][TOP]
>UniRef100_C5DPF1 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5DPF1_ZYGRC
Length = 650
Score = 65.1 bits (157), Expect = 2e-09
Identities = 45/108 (41%), Positives = 53/108 (49%), Gaps = 6/108 (5%)
Frame = +1
Query: 58 SFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*IL------PKRCR 219
S EFFPPKTE G NLLERM+RM A P + W L K
Sbjct: 16 SLEFFPPKTETGKQNLLERMERMTALGPL---FATVTWGAGGSTAEKTLELASLAQKNLN 72
Query: 220 IP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQD 363
+P CT+ M +DDAL K+ G+ N+LALRGDPP GQD
Sbjct: 73 LPICMHLTCTN----MDRNIIDDALTRCKAAGIHNILALRGDPPIGQD 116
[61][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 65.1 bits (157), Expect = 2e-09
Identities = 48/136 (35%), Positives = 65/136 (47%), Gaps = 10/136 (7%)
Frame = +1
Query: 10 EKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM 189
+K+ E S R SFE+FPPKT GV NL +RMDRM P+ + G +
Sbjct: 5 QKLQEQETS--GRPGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGSRSEL 62
Query: 190 *H*ILPKRCRIP*VWKP*----------CTSPAPTMPDEKMDDALETIKSNGLQNVLALR 339
C + + + CT MP E++D ALE+ + G N+LALR
Sbjct: 63 -------TCEMVRIAQTVFGLETCMHLTCTD----MPRERVDAALESAYNAGCTNILALR 111
Query: 340 GDPPHGQDKFVQVEGG 387
GDPP Q+K+ EGG
Sbjct: 112 GDPPREQEKWEAAEGG 127
[62][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 65.1 bits (157), Expect = 2e-09
Identities = 46/122 (37%), Positives = 57/122 (46%), Gaps = 10/122 (8%)
Frame = +1
Query: 58 SFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*ILPKRCRIP*VWK 237
SFEFFPPKT GV NL +RMDRM PS + I G + C + V +
Sbjct: 19 SFEFFPPKTAQGVQNLYDRMDRMHGLGPSFI-------DITWGAGGRLSDLTCEMVSVAQ 71
Query: 238 P*----------CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
CT MP EK+D AL+ G N+LALRGDPP ++ + E G
Sbjct: 72 SVYGLETCMHLTCTD----MPVEKVDQALQAAYKAGCTNILALRGDPPREKEAWEAAENG 127
Query: 388 LC 393
C
Sbjct: 128 FC 129
[63][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 47.4 bits (111), Expect(2) = 3e-09
Identities = 40/123 (32%), Positives = 57/123 (46%), Gaps = 7/123 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T G VNL+ R DRM A P V + G ++ ++
Sbjct: 59 FSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNY 118
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGLC 393
C + + C + E++ L K GL+N+LALRGDP D++ + EGG
Sbjct: 119 CGLETILHMTCCHQS----REEITGHLNKAKQLGLKNILALRGDPI--GDQWEEEEGGFN 172
Query: 394 LCT 402
T
Sbjct: 173 YAT 175
Score = 37.4 bits (85), Expect(2) = 3e-09
Identities = 16/26 (61%), Positives = 19/26 (73%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A DLVKHIR + GDYF + +AGY
Sbjct: 171 FNYATDLVKHIRNEFGDYFDVCVAGY 196
[64][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 47.4 bits (111), Expect(2) = 3e-09
Identities = 40/123 (32%), Positives = 57/123 (46%), Gaps = 7/123 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T G VNL+ R DRM A P V + G ++ ++
Sbjct: 59 FSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNY 118
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGLC 393
C + + C + E++ L K GL+N+LALRGDP D++ + EGG
Sbjct: 119 CGLETILHMTCCHQS----REEITGHLNKAKQLGLKNILALRGDPI--GDQWEEEEGGFN 172
Query: 394 LCT 402
T
Sbjct: 173 YAT 175
Score = 37.4 bits (85), Expect(2) = 3e-09
Identities = 16/26 (61%), Positives = 19/26 (73%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A DLVKHIR + GDYF + +AGY
Sbjct: 171 FNYATDLVKHIRNEFGDYFDVCVAGY 196
[65][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 45.1 bits (105), Expect(2) = 3e-09
Identities = 39/118 (33%), Positives = 56/118 (47%), Gaps = 7/118 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T G VNL+ R D+M A P V + G ++ ++
Sbjct: 59 FSLEFFPPRTAQGAVNLISRFDQMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
C + V C + E++ L K GL+N+LALRGDP D++ + EGG
Sbjct: 119 CGLETVLHMTCCRQS----REEITGYLHKAKRLGLKNILALRGDPV--GDQWEEEEGG 170
Score = 39.7 bits (91), Expect(2) = 3e-09
Identities = 16/26 (61%), Positives = 21/26 (80%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F+ A DLVKHIR++ GDYF + +AGY
Sbjct: 171 FSYAADLVKHIRSEFGDYFDVCVAGY 196
[66][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 64.7 bits (156), Expect = 3e-09
Identities = 44/120 (36%), Positives = 58/120 (48%), Gaps = 9/120 (7%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVG---------CWRINRGM*H*ILP 207
FSFE+FPPKT GV NL +RM+RM P + G C + + + L
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMERMYNFGPKFVDITWGAGGRIAELTCEMVVQAQTYLGLE 77
Query: 208 KRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
+ CT M +EK++DAL G N+LALRGDPP Q+K+ EGG
Sbjct: 78 ACMHLT------CTD----MGEEKVNDALRKAYKAGCTNILALRGDPPREQEKWEATEGG 127
[67][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 64.7 bits (156), Expect = 3e-09
Identities = 45/129 (34%), Positives = 59/129 (45%), Gaps = 10/129 (7%)
Frame = +1
Query: 31 ASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*ILPK 210
A + + FSFEFFPPKT GV NL +RMDRM P + G + +
Sbjct: 10 AREEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHSKL------- 62
Query: 211 RCRIP*VWKP----------*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQ 360
C + V + CT M K+DDAL +G N+LALRGDPP +
Sbjct: 63 TCEMVKVAQTVYGLETCMHLTCTD----MEKSKLDDALREAYQSGCTNILALRGDPPRER 118
Query: 361 DKFVQVEGG 387
+K+ GG
Sbjct: 119 EKWEATAGG 127
[68][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 64.3 bits (155), Expect = 4e-09
Identities = 45/129 (34%), Positives = 65/129 (50%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
K+ EK+ +A R +SFEFFPP+T G+ NL +R++RM P + G N
Sbjct: 2 KITEKLQKAEKE--GRPFWSFEFFPPRTAQGLQNLYDRIERMRDLGPEFIDITWGAGGKN 59
Query: 181 RGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQ 360
+ + L + C+ + MP EK++ AL KS+G QN+LALRGDP G
Sbjct: 60 ADLTN-SLVQVCQATIGIETCMHLCCTEMPKEKVEWALREAKSHGCQNILALRGDPVAGT 118
Query: 361 DKFVQVEGG 387
+ GG
Sbjct: 119 STWEPTPGG 127
[69][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 64.3 bits (155), Expect = 4e-09
Identities = 45/132 (34%), Positives = 64/132 (48%), Gaps = 3/132 (2%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
K+ EK+ + + + +SFE+F PKT GV NL +RMDRM + S+ + W
Sbjct: 2 KITEKLEQHRQTS-GKPTYSFEYFVPKTTQGVQNLYDRMDRM--YEASLPQFIDITWNAG 58
Query: 181 RGM*H*I---LPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
G + L + + MP +DDALE +G QN+LALRGDPP
Sbjct: 59 GGRLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPP 118
Query: 352 HGQDKFVQVEGG 387
+ + VEGG
Sbjct: 119 RDAENWTPVEGG 130
[70][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 64.3 bits (155), Expect = 4e-09
Identities = 46/114 (40%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCW-RINRGM*H*ILPKRC--RIP 225
FSFE+FPPKT GV NL +RMDRM P + G RI +L + +
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIAELTCEMVLQAQAVYGLE 77
Query: 226 *VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
CT M EK++DAL G N+LALRGDPP QDK+ +GG
Sbjct: 78 TCMHLTCTD----MGVEKVNDALLKAYKAGCTNILALRGDPPRDQDKWTAADGG 127
[71][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 64.3 bits (155), Expect = 4e-09
Identities = 45/132 (34%), Positives = 64/132 (48%), Gaps = 3/132 (2%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
K+ EK+ + + + +SFE+F PKT GV NL +RMDRM + S+ + W
Sbjct: 2 KITEKLEQHRQTS-GKPTYSFEYFVPKTTQGVQNLYDRMDRM--YEASLPQFIDITWNAG 58
Query: 181 RGM*H*I---LPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
G + L + + MP +DDALE +G QN+LALRGDPP
Sbjct: 59 GGRLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPP 118
Query: 352 HGQDKFVQVEGG 387
+ + VEGG
Sbjct: 119 RDAENWTPVEGG 130
[72][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 64.3 bits (155), Expect = 4e-09
Identities = 45/132 (34%), Positives = 64/132 (48%), Gaps = 3/132 (2%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
K+ EK+ + + + +SFE+F PKT GV NL +RMDRM + S+ + W
Sbjct: 2 KITEKLEQHRQTS-GKPTYSFEYFVPKTTQGVQNLYDRMDRM--YEASLPQFIDITWNAG 58
Query: 181 RGM*H*I---LPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
G + L + + MP +DDALE +G QN+LALRGDPP
Sbjct: 59 GGRLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPP 118
Query: 352 HGQDKFVQVEGG 387
+ + VEGG
Sbjct: 119 RDAENWTPVEGG 130
[73][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 45.1 bits (105), Expect(2) = 5e-09
Identities = 36/105 (34%), Positives = 49/105 (46%), Gaps = 7/105 (6%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T G VNL+ R DRM A P V + G ++ I+
Sbjct: 54 FSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMIIANTAVDY 113
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDP 348
C + V C+ +++ L K GL+N+LALRGDP
Sbjct: 114 CGLETVLHMTCSQ----QNRDEITSHLHKAKRLGLKNILALRGDP 154
Score = 38.9 bits (89), Expect(2) = 5e-09
Identities = 17/26 (65%), Positives = 21/26 (80%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F+ A DLVKHIR++ GDYF I +AGY
Sbjct: 166 FSHAVDLVKHIRSEFGDYFDICVAGY 191
[74][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 63.9 bits (154), Expect = 5e-09
Identities = 46/114 (40%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCW-RINRGM*H*ILPKRC--RIP 225
FSFE+FPPKT GV NL +RMDRM P + G RI +L + +
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIAELTCEMVLQAQAVYGLE 77
Query: 226 *VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
CT M EK++DAL G N+LALRGDPP QDK+ +GG
Sbjct: 78 TCMHLTCTD----MGVEKVNDALLKAYKAGCTNILALRGDPPRAQDKWEAADGG 127
[75][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 63.9 bits (154), Expect = 5e-09
Identities = 46/132 (34%), Positives = 69/132 (52%), Gaps = 3/132 (2%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*Y-YVGCWRI 177
K+ K+ +A A+D + FSFEFF PKT GV NL +RMDRM P + + R+
Sbjct: 2 KISHKLEKAHAAD-STPTFSFEFFVPKTSQGVNNLYDRMDRMYQLGPQFIDITWNAGGRL 60
Query: 178 NRGM*H*ILPKRCR--IP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
+ + + + CT MP + +++AL++ G QN+LALRGDPP
Sbjct: 61 SNLTNEMVATAQSALGLETCMHLTCTG----MPKQLVENALQSAFDGGCQNILALRGDPP 116
Query: 352 HGQDKFVQVEGG 387
+K+ V+GG
Sbjct: 117 VESEKWEAVDGG 128
[76][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 63.9 bits (154), Expect = 5e-09
Identities = 48/127 (37%), Positives = 62/127 (48%), Gaps = 4/127 (3%)
Frame = +1
Query: 19 HEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCW----RINRG 186
H AA P+ SFEFFPPKT GV NL +RMDRM PS + G +
Sbjct: 9 HSEAAGRPS---ISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFVDITWGAGGRLSDLTAE 65
Query: 187 M*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDK 366
M + + + CT MP EK+D AL++ G N+LALRGDPP ++
Sbjct: 66 MVN-VSQSVYGLETCMHLTCTD----MPREKVDWALQSAYKAGCTNILALRGDPPREKEA 120
Query: 367 FVQVEGG 387
+ EGG
Sbjct: 121 WAPTEGG 127
[77][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 46.2 bits (108), Expect(2) = 6e-09
Identities = 38/118 (32%), Positives = 56/118 (47%), Gaps = 7/118 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T +G VNL+ R DRM A P V + G ++ ++
Sbjct: 101 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 160
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
C + + C E++ L K GL+N++ALRGDP D++ + EGG
Sbjct: 161 CGLETILHMTCCCQRL----EEITGHLHKAKQLGLKNIMALRGDPI--GDQWEEEEGG 212
Score = 37.4 bits (85), Expect(2) = 6e-09
Identities = 16/26 (61%), Positives = 20/26 (76%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A DLVKHIR++ GDYF + +AGY
Sbjct: 213 FNYAVDLVKHIRSEFGDYFDLCVAGY 238
[78][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 46.2 bits (108), Expect(2) = 6e-09
Identities = 38/118 (32%), Positives = 56/118 (47%), Gaps = 7/118 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T +G VNL+ R DRM A P V + G ++ ++
Sbjct: 83 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 142
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
C + + C E++ L K GL+N++ALRGDP D++ + EGG
Sbjct: 143 CGLETILHMTCCCQRL----EEITGHLHKAKQLGLKNIMALRGDPI--GDQWEEEEGG 194
Score = 37.4 bits (85), Expect(2) = 6e-09
Identities = 16/26 (61%), Positives = 20/26 (76%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A DLVKHIR++ GDYF + +AGY
Sbjct: 195 FNYAVDLVKHIRSEFGDYFDLCVAGY 220
[79][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 46.2 bits (108), Expect(2) = 6e-09
Identities = 38/118 (32%), Positives = 56/118 (47%), Gaps = 7/118 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T +G VNL+ R DRM A P V + G ++ ++
Sbjct: 60 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 119
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
C + + C E++ L K GL+N++ALRGDP D++ + EGG
Sbjct: 120 CGLETILHMTCCCQRL----EEITGHLHKAKQLGLKNIMALRGDPI--GDQWEEEEGG 171
Score = 37.4 bits (85), Expect(2) = 6e-09
Identities = 16/26 (61%), Positives = 20/26 (76%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A DLVKHIR++ GDYF + +AGY
Sbjct: 172 FNYAVDLVKHIRSEFGDYFDLCVAGY 197
[80][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 63.5 bits (153), Expect = 7e-09
Identities = 46/135 (34%), Positives = 64/135 (47%), Gaps = 9/135 (6%)
Frame = +1
Query: 10 EKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVG-------- 165
EK+ + A+ ++ SFEFFPPKT GV NL +RMDRM PS + G
Sbjct: 5 EKLAQNEAA--GKIGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLSDL 62
Query: 166 -CWRINRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRG 342
C +N + + CT MP E++D AL+ G N+LALRG
Sbjct: 63 TCEMVN------VAQSVYGLETCMHLTCTD----MPQERVDAALQAAYKAGCTNILALRG 112
Query: 343 DPPHGQDKFVQVEGG 387
DPP ++ + +GG
Sbjct: 113 DPPREKEVWEAADGG 127
[81][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 63.2 bits (152), Expect = 9e-09
Identities = 42/120 (35%), Positives = 59/120 (49%), Gaps = 9/120 (7%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVG---------CWRINRGM*H*ILP 207
FSFE+FPPKT GV NL +RMDRM P + G C + + + L
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIAELTCEMVAQAQAYLGLE 77
Query: 208 KRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
+ CT M +EK+++AL+ G N+LALRGDPP ++++ EGG
Sbjct: 78 TCMHLT------CTD----MGEEKVNNALQRAYKAGCTNILALRGDPPREKERWEAAEGG 127
[82][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 63.2 bits (152), Expect = 9e-09
Identities = 41/135 (30%), Positives = 70/135 (51%), Gaps = 11/135 (8%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCW--- 171
K+ +KI AA DP++ ++FEFFPP+T+ G NL+ R+ R+ +P + G
Sbjct: 2 KLSDKI---AAHDPSQPFYTFEFFPPRTDQGFENLVSRISRLATLNPLAISVTWGAGGST 58
Query: 172 --------RINRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNV 327
+ +G H L + CT+ M +D+ L+ ++ G+QN+
Sbjct: 59 KDRSLELASLTQGDYH--LDTLLHLT------CTN----MEQGLVDEVLKAVRDRGIQNI 106
Query: 328 LALRGDPPHGQDKFV 372
LALRGDPP G+++++
Sbjct: 107 LALRGDPPRGEEEWI 121
[83][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 62.8 bits (151), Expect = 1e-08
Identities = 45/131 (34%), Positives = 59/131 (45%), Gaps = 10/131 (7%)
Frame = +1
Query: 25 AAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*IL 204
A A + FSFEFFPPKT GV NL +RMDRM P + G + +
Sbjct: 8 AQAKAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHSKL----- 62
Query: 205 PKRCRIP*VWKP----------*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPH 354
C + V + CT M K+D+AL +G N+LALRGDPP
Sbjct: 63 --TCEMVKVAQTVYGLETCMHLTCTD----MEKTKLDEALRDAYQSGCTNILALRGDPPR 116
Query: 355 GQDKFVQVEGG 387
++K+ GG
Sbjct: 117 EREKWEATAGG 127
[84][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 62.8 bits (151), Expect = 1e-08
Identities = 43/120 (35%), Positives = 58/120 (48%), Gaps = 9/120 (7%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVG---------CWRINRGM*H*ILP 207
FSFE+FPPKT GV NL +RM+RM P + G C + + + L
Sbjct: 18 FSFEYFPPKTTQGVQNLYDRMERMNNFGPKFIDITWGAGGRIAELTCEMVVQAQTYLGLE 77
Query: 208 KRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
+ CT M +EK++DAL G N+LALRGDPP ++K+ EGG
Sbjct: 78 TCMHLT------CTD----MGEEKVNDALRKAYKAGCTNILALRGDPPREKEKWEAAEGG 127
[85][TOP]
>UniRef100_B2KFL5 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Mus musculus
RepID=B2KFL5_MOUSE
Length = 194
Score = 50.1 bits (118), Expect(2) = 1e-08
Identities = 40/123 (32%), Positives = 56/123 (45%), Gaps = 7/123 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T +G VNL+ R DRM A P V + G ++ ++
Sbjct: 59 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGLC 393
C + + C P E++ L K GL+N++ALRGDP D + EGG
Sbjct: 119 CGLETILHMTCCQQRP----EEITGHLHRAKQLGLKNIMALRGDPV--GDHWEAEEGGFS 172
Query: 394 LCT 402
T
Sbjct: 173 YAT 175
Score = 32.3 bits (72), Expect(2) = 1e-08
Identities = 14/24 (58%), Positives = 17/24 (70%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIA 460
F+ A DLVKHIR + DYF I +A
Sbjct: 171 FSYATDLVKHIRTEFADYFDICVA 194
[86][TOP]
>UniRef100_A2A7F9 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Mus musculus
RepID=A2A7F9_MOUSE
Length = 194
Score = 50.1 bits (118), Expect(2) = 1e-08
Identities = 40/123 (32%), Positives = 56/123 (45%), Gaps = 7/123 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T +G VNL+ R DRM A P V + G ++ ++
Sbjct: 59 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGLC 393
C + + C P E++ L K GL+N++ALRGDP D + EGG
Sbjct: 119 CGLETILHMTCCQQRP----EEITGHLHRAKQLGLKNIMALRGDPV--GDHWEAEEGGFS 172
Query: 394 LCT 402
T
Sbjct: 173 YAT 175
Score = 32.3 bits (72), Expect(2) = 1e-08
Identities = 14/24 (58%), Positives = 17/24 (70%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIA 460
F+ A DLVKHIR + DYF I +A
Sbjct: 171 FSYATDLVKHIRTEFADYFDICVA 194
[87][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TTE9_VANPO
Length = 612
Score = 37.4 bits (85), Expect(3) = 2e-08
Identities = 16/27 (59%), Positives = 20/27 (74%)
Frame = +1
Query: 280 MDDALETIKSNGLQNVLALRGDPPHGQ 360
+D ALE ++G N+LALRGDPP GQ
Sbjct: 70 IDAALEQAHASGCHNILALRGDPPRGQ 96
Score = 34.3 bits (77), Expect(3) = 2e-08
Identities = 15/33 (45%), Positives = 23/33 (69%)
Frame = +2
Query: 368 SSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
SS +F A LV++IR+K+G++F I +AGY
Sbjct: 114 SSDGDCNFKFAAQLVRYIRSKYGNHFAIGVAGY 146
Score = 29.6 bits (65), Expect(3) = 2e-08
Identities = 11/16 (68%), Positives = 14/16 (87%)
Frame = +3
Query: 216 QNTVGVETMMHLTCTN 263
Q+ +G+ET MHLTCTN
Sbjct: 49 QSVLGLETCMHLTCTN 64
[88][TOP]
>UniRef100_C9S7I4 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S7I4_9PEZI
Length = 181
Score = 62.0 bits (149), Expect = 2e-08
Identities = 44/120 (36%), Positives = 57/120 (47%), Gaps = 9/120 (7%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVG---------CWRINRGM*H*ILP 207
FSFE+FPPKT GV NL +RMDRM P + G C + + L
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIAELTCEMVTQAQSVYGLE 77
Query: 208 KRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
+ CT M EK++DAL G N+LALRGDPP ++K+V +GG
Sbjct: 78 TCMHLT------CTD----MGLEKVNDALRKGYKAGCTNILALRGDPPREKEKWVAADGG 127
[89][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 61.2 bits (147), Expect = 3e-08
Identities = 46/126 (36%), Positives = 60/126 (47%), Gaps = 9/126 (7%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*Y-------- 156
K+ EK+ A + FSFEFF PKT GV NL +RMDRM SP +
Sbjct: 2 KITEKLSSAHRREDAPPTFSFEFFTPKTAQGVQNLYDRMDRMYNLSPQFIDITWNAGGRS 61
Query: 157 -YVGCWRINRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLA 333
+ C IN L + CT+ M E +D+AL++ +G QN+LA
Sbjct: 62 SNLTCEMINTAQTVLGLETCMHLT------CTN----MTLEVIDEALKSAYDSGCQNILA 111
Query: 334 LRGDPP 351
LRGDPP
Sbjct: 112 LRGDPP 117
[90][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 41.6 bits (96), Expect(2) = 4e-08
Identities = 37/130 (28%), Positives = 54/130 (41%), Gaps = 6/130 (4%)
Frame = +1
Query: 4 VIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINR 183
+I+KI + S +S EFFPP+T+ G VNL+ R DR+ +P + W
Sbjct: 26 IIQKIRKRINSGDK--FYSLEFFPPRTDSGGVNLIARFDRLAIGNPL---FIDVTWHPKG 80
Query: 184 GM*H*ILPKRCRIP*VWKP*CTSPAP------TMPDEKMDDALETIKSNGLQNVLALRGD 345
+ I C + E +D L K GL+N+LALRGD
Sbjct: 81 NSGGDEVTASLTIASAALNFCGLDSMLHMTCINSTTEDIDKYLRKAKKQGLRNILALRGD 140
Query: 346 PPHGQDKFVQ 375
D+ V+
Sbjct: 141 VSDSIDESVR 150
Score = 39.3 bits (90), Expect(2) = 4e-08
Identities = 18/33 (54%), Positives = 22/33 (66%)
Frame = +2
Query: 368 SSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
S R + A DLVKHIR + G+YFGI +AGY
Sbjct: 148 SVRHTKELKYASDLVKHIRKEFGNYFGIAVAGY 180
[91][TOP]
>UniRef100_Q04NW1 Methylenetetrahydrofolate reductase n=2 Tax=Leptospira
borgpetersenii serovar Hardjo-bovis RepID=Q04NW1_LEPBJ
Length = 290
Score = 60.8 bits (146), Expect = 4e-08
Identities = 40/115 (34%), Positives = 58/115 (50%), Gaps = 3/115 (2%)
Frame = +1
Query: 52 VFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*ILP---KRCRI 222
V+SFEFFPPKT+DG + L+ + + P + G R IL K
Sbjct: 15 VYSFEFFPPKTQDGDLKLMGTVKELARLDPDFVTVTYGAGGSTRDKTAQILSEISKNYSF 74
Query: 223 P*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
P V C +++ L+ I+S+G+ N++ALRGDPP G+ KF + EGG
Sbjct: 75 PTVSHFTCVGAN----QDQIFKTLKEIRSSGIVNLMALRGDPPKGEGKFKKTEGG 125
[92][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 43.1 bits (100), Expect(2) = 5e-08
Identities = 38/118 (32%), Positives = 55/118 (46%), Gaps = 7/118 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T G VNL+ R D+M A P V + G ++ I+
Sbjct: 57 FSLEFFPPRTAQGAVNLISRFDQMGAGGPLFVDVTWHPAGDPGSDKETSSMIIANTAVDY 116
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
C + V C +++ L K GL+N++ALRGDP D++ + EGG
Sbjct: 117 CGLETVLHMTCCH----QTRDEITRHLHKAKRLGLKNIMALRGDPI--GDEWEEEEGG 168
Score = 37.4 bits (85), Expect(2) = 5e-08
Identities = 16/26 (61%), Positives = 20/26 (76%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A DLVKHIR++ GDYF + +AGY
Sbjct: 169 FNHAVDLVKHIRSEFGDYFDVCVAGY 194
[93][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 60.1 bits (144), Expect = 7e-08
Identities = 42/123 (34%), Positives = 60/123 (48%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
K+ KI A A R+ +SFE+FPP+T G+ NL +R++RM P +
Sbjct: 18 KITNKI--AKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERMADLGPEFVDITWNAGGRT 75
Query: 181 RGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQ 360
+ L K + MP EK+D AL+ K G +N+LALRGDPP GQ
Sbjct: 76 SDL-TASLVKTVHTYIGLETCMHLTCTNMPREKIDTALKEAKEFGCRNILALRGDPPAGQ 134
Query: 361 DKF 369
++
Sbjct: 135 SEW 137
[94][TOP]
>UniRef100_C5M548 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M548_CANTT
Length = 633
Score = 60.1 bits (144), Expect = 7e-08
Identities = 42/114 (36%), Positives = 57/114 (50%), Gaps = 6/114 (5%)
Frame = +1
Query: 40 PNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*IL----- 204
P+ SFEFFPPKT+ G NLL R++RM A +P + W L
Sbjct: 13 PDERFVSFEFFPPKTDSGFRNLLARLNRMSAFNPL---FITITWGAGGSTSEKSLDLAAT 69
Query: 205 -PKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQD 363
K I V CT+ E +D+AL K+NG++N+LALRGDPP ++
Sbjct: 70 CQKEVGITTVLHLTCTN----TNKEIIDEALARAKANGIRNILALRGDPPRAEE 119
[95][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 60.1 bits (144), Expect = 7e-08
Identities = 45/133 (33%), Positives = 68/133 (51%), Gaps = 4/133 (3%)
Frame = +1
Query: 1 KVIEKIHE-AAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*Y-YVGCWR 174
+V EK+ + A+ ++ FSFEFF PKT GV NL +RMDRM P + + R
Sbjct: 2 RVSEKLQKNREANGTSKATFSFEFFVPKTSQGVQNLYDRMDRMYQTHPQFIDITWNAGGR 61
Query: 175 INRGM*H*ILPKR--CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDP 348
+++ + + + CT+ MP + +DDAL+ +G QN+LALRGD
Sbjct: 62 LSQLSTELVSTSQSVLGLETCMHLTCTN----MPRQLIDDALQKAYESGCQNILALRGDA 117
Query: 349 PHGQDKFVQVEGG 387
P ++ EGG
Sbjct: 118 PITSSEWKPCEGG 130
[96][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 60.1 bits (144), Expect = 7e-08
Identities = 43/122 (35%), Positives = 62/122 (50%), Gaps = 5/122 (4%)
Frame = +1
Query: 1 KVIEKIHEA--AASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWR 174
K+ EK+H+A ++ P FSFEFF PKT GV NL +RMDRM +P +
Sbjct: 2 KISEKLHQAHSGSTRPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 61
Query: 175 INRGM*H*IL---PKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGD 345
+ + + ++ + CT+ M E +D+AL +G QN+LALRGD
Sbjct: 62 RSSSLTNEMVYTAQSTLGLETCMHLTCTN----MKIELIDEALSKAYKSGCQNILALRGD 117
Query: 346 PP 351
PP
Sbjct: 118 PP 119
[97][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 44.7 bits (104), Expect(2) = 8e-08
Identities = 41/134 (30%), Positives = 55/134 (41%), Gaps = 18/134 (13%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL------------------*YYVGCWRIN 180
FS EFFPP+T G NL+ R +RMV P + + C +N
Sbjct: 47 FSLEFFPPRTPQGAANLISRFERMVQGGPMFMDITWHPAGDPGNSDKETSSMSIACAALN 106
Query: 181 RGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQ 360
+L C C S T D + L+ K G++N+LALRGDP G
Sbjct: 107 YVGHETMLHMSC---------CNS---TKDDIRRH--LDKAKELGIRNILALRGDPIVG- 151
Query: 361 DKFVQVEGGLCLCT 402
D++ VE G T
Sbjct: 152 DEWKYVEDGFNYAT 165
Score = 35.0 bits (79), Expect(2) = 8e-08
Identities = 15/26 (57%), Positives = 19/26 (73%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A D+VK IRA+ GDYF + +AGY
Sbjct: 161 FNYATDMVKFIRAEFGDYFTVCVAGY 186
[98][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 47.0 bits (110), Expect(2) = 1e-07
Identities = 38/120 (31%), Positives = 56/120 (46%), Gaps = 7/120 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*I-----LPKRCR 219
+SFEFFPPKTE G+ NLL R+DRM + + W ++ + K
Sbjct: 41 YSFEFFPPKTEAGLDNLLTRIDRMAQRLDPL--FIDVTWGSDKTSARTMALASHAQKYLG 98
Query: 220 IP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFV--QVEGGLC 393
+ + C M +++ L+ K G+ N+LALRGDPP + + V GG C
Sbjct: 99 VDVLLHLSCQG----MTRDQLIRVLDQAKVLGIHNILALRGDPPKAKKHWQVGDVSGGEC 154
Score = 32.3 bits (72), Expect(2) = 1e-07
Identities = 14/23 (60%), Positives = 18/23 (78%)
Frame = +2
Query: 398 ARDLVKHIRAKHGDYFGITIAGY 466
A DLV+ IR +GDYFGI +AG+
Sbjct: 157 AIDLVRLIRNTYGDYFGIAVAGH 179
[99][TOP]
>UniRef100_UPI00003BE162 hypothetical protein DEHA0F09867g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE162
Length = 642
Score = 59.3 bits (142), Expect = 1e-07
Identities = 42/120 (35%), Positives = 60/120 (50%), Gaps = 6/120 (5%)
Frame = +1
Query: 31 ASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*IL-- 204
A P+ SFEFFPPKT+ G NLL R++RM+A +P + W L
Sbjct: 10 ALKPHERFVSFEFFPPKTDTGFRNLLARLNRMLALNPL---FITVTWGAGGSTSEKSLDL 66
Query: 205 ----PKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFV 372
K + V CT+ E +D+ALE K G++N+LALRGDPP ++ ++
Sbjct: 67 AATCQKEIGLTTVLHLTCTN----TNKEIIDNALEKAKEQGIRNILALRGDPPRTEEYWI 122
[100][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 59.3 bits (142), Expect = 1e-07
Identities = 49/126 (38%), Positives = 61/126 (48%), Gaps = 9/126 (7%)
Frame = +1
Query: 1 KVIEKIHEA-AASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRI 177
K+ EK+ +A S+P FSFEFF PKT GV NL +RMDRM +P + W
Sbjct: 2 KISEKLTQAHKGSNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDI---TW-- 56
Query: 178 NRGM*H*ILPKRCRIP*VWKP*CTSPAPT--------MPDEKMDDALETIKSNGLQNVLA 333
N G L V+ T T M E +D+ALE +G QN+LA
Sbjct: 57 NAGGRSSTLTNEM----VYTAQSTLGLETCMHLTCTNMKVELIDEALEKAFKSGCQNILA 112
Query: 334 LRGDPP 351
LRGDPP
Sbjct: 113 LRGDPP 118
[101][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 59.3 bits (142), Expect = 1e-07
Identities = 49/126 (38%), Positives = 60/126 (47%), Gaps = 9/126 (7%)
Frame = +1
Query: 1 KVIEKIHEA-AASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRI 177
K+ EK+ +A S P FSFEFF PKT GV NL +RMDRM +P + W
Sbjct: 2 KISEKLSQAHRGSKPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDI---TW-- 56
Query: 178 NRGM*H*ILPKRCRIP*VWKP*CTSPAPT--------MPDEKMDDALETIKSNGLQNVLA 333
N G L V+ T T M E +D+ALE +G QN+LA
Sbjct: 57 NAGGRSSTLTNEM----VYTAQSTLGLETCMHLTCTNMKVELIDEALEKAYKSGCQNILA 112
Query: 334 LRGDPP 351
LRGDPP
Sbjct: 113 LRGDPP 118
[102][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 59.3 bits (142), Expect = 1e-07
Identities = 41/120 (34%), Positives = 56/120 (46%), Gaps = 9/120 (7%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVG---------CWRINRGM*H*ILP 207
FSFE+FPPKT GV NL +RM+RM P + G C + + + L
Sbjct: 13 FSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIAELTCEMVTQAQTYFGLE 72
Query: 208 KRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
+ CT M EK++DAL G N+LALRGDPP ++K+ + G
Sbjct: 73 TCMHLT------CTD----MGVEKVNDALSKAYKAGCTNILALRGDPPRDKEKWEAAQDG 122
[103][TOP]
>UniRef100_UPI000151A866 hypothetical protein PGUG_01501 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151A866
Length = 642
Score = 58.9 bits (141), Expect = 2e-07
Identities = 43/126 (34%), Positives = 62/126 (49%), Gaps = 6/126 (4%)
Frame = +1
Query: 4 VIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINR 183
V++KI+ D SFEFFPPKT+ G NLL R+ RM+A +P + W
Sbjct: 3 VVQKINSLGPQDR---FISFEFFPPKTDTGFRNLLARLHRMLALNPL---FITVTWGAGG 56
Query: 184 GM*H*IL------PKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGD 345
L K + V CT+ + +D+AL+ K NG++N+LALRGD
Sbjct: 57 STSEKSLDLAITCQKELGLTTVLHLTCTNTNKDI----IDNALQRAKENGIRNILALRGD 112
Query: 346 PPHGQD 363
PP ++
Sbjct: 113 PPRTEE 118
[104][TOP]
>UniRef100_B9XQY3 Methylenetetrahydrofolate reductase n=1 Tax=bacterium Ellin514
RepID=B9XQY3_9BACT
Length = 303
Score = 58.9 bits (141), Expect = 2e-07
Identities = 43/125 (34%), Positives = 66/125 (52%), Gaps = 4/125 (3%)
Frame = +1
Query: 25 AAASDPNRVVFSFEFFPPKTEDGVVNLLER----MDRMVAHSPSVL*YYVGCWRINRGM* 192
AA +D ++ V SFEFFPPKT++G LLE+ + R+ SV G R M
Sbjct: 15 AAKADAHQPVISFEFFPPKTDEGDRALLEKTIPALLRLKPDFCSVTYGAGGGTRDKTLMI 74
Query: 193 H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFV 372
+ + ++P + C + E++ D +E +S G++N+LALRGDPP G +F
Sbjct: 75 VDRIQREHQLPTMLHLTCVNATR----EQLRDVIEQARSLGVKNILALRGDPPGGNGEFK 130
Query: 373 QVEGG 387
+GG
Sbjct: 131 MTDGG 135
[105][TOP]
>UniRef100_Q752W6 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q752W6_ASHGO
Length = 635
Score = 58.9 bits (141), Expect = 2e-07
Identities = 44/124 (35%), Positives = 58/124 (46%), Gaps = 6/124 (4%)
Frame = +1
Query: 34 SDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*IL--- 204
S+ NR S EFFPPKT+ G NLL R++RM A P + W L
Sbjct: 9 SELNRPSLSLEFFPPKTDSGKSNLLARIERMSAMDPL---FITVTWGAGGSTAEKTLELA 65
Query: 205 ---PKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQ 375
+ IP CT+ T+ +D AL K G++N+LALRGD P D+
Sbjct: 66 ALAQRELNIPVCMHLTCTNMDRTI----LDKALMRAKEAGIRNILALRGDMPLAADEEEH 121
Query: 376 VEGG 387
V+GG
Sbjct: 122 VDGG 125
[106][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 43.1 bits (100), Expect(2) = 2e-07
Identities = 34/105 (32%), Positives = 49/105 (46%), Gaps = 7/105 (6%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T G VNL+ R DRM A P V + G ++ ++
Sbjct: 64 FSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 123
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDP 348
C + + C + +K+ L K GL+N++ALRGDP
Sbjct: 124 CGLESILHLTCCN----QTKDKITGYLGKAKRLGLKNIMALRGDP 164
Score = 35.4 bits (80), Expect(2) = 2e-07
Identities = 16/26 (61%), Positives = 19/26 (73%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A DLVKHIR++ DYF I +AGY
Sbjct: 176 FNYAIDLVKHIRSEFDDYFDICVAGY 201
[107][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 43.1 bits (100), Expect(2) = 2e-07
Identities = 34/105 (32%), Positives = 49/105 (46%), Gaps = 7/105 (6%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T G VNL+ R DRM A P V + G ++ ++
Sbjct: 64 FSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 123
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDP 348
C + + C + +K+ L K GL+N++ALRGDP
Sbjct: 124 CGLESILHLTCCN----QTKDKITGYLGKAKRLGLKNIMALRGDP 164
Score = 35.4 bits (80), Expect(2) = 2e-07
Identities = 16/26 (61%), Positives = 19/26 (73%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A DLVKHIR++ DYF I +AGY
Sbjct: 176 FNYAIDLVKHIRSEFDDYFDICVAGY 201
[108][TOP]
>UniRef100_B4UHX4 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter sp. K
RepID=B4UHX4_ANASK
Length = 300
Score = 58.5 bits (140), Expect = 2e-07
Identities = 40/114 (35%), Positives = 56/114 (49%)
Frame = +1
Query: 31 ASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*ILPK 210
A + +FSFEFFPPKT+DGV L E ++ + P+ + G R ++ +
Sbjct: 10 ARERGEPIFSFEFFPPKTDDGVRGLFETVEALRPLGPAYVSVTYGAGGSTRAKTIELVKR 69
Query: 211 RCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFV 372
R V + DE + L+ + G+QNVLALRGDPP GQ FV
Sbjct: 70 LKRDAEVEAMAHVTCVGASRDE-IAAVLDEVAEAGIQNVLALRGDPPRGQGAFV 122
[109][TOP]
>UniRef100_P46151 Methylenetetrahydrofolate reductase 1 n=1 Tax=Saccharomyces
cerevisiae RepID=MTHR1_YEAST
Length = 657
Score = 58.5 bits (140), Expect = 2e-07
Identities = 44/122 (36%), Positives = 59/122 (48%), Gaps = 3/122 (2%)
Frame = +1
Query: 7 IEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRG 186
I ++ A AS S EFFPPKTE G NL+ERM RM A P + G
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 187 ---M*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHG 357
+ + IP CT+ + +DDAL+ + G++N+LALRGDPP G
Sbjct: 59 KTLTLASLAQQTLNIPVCMHLTCTNTEKAI----IDDALDRCYNAGIRNILALRGDPPIG 114
Query: 358 QD 363
+D
Sbjct: 115 ED 116
[110][TOP]
>UniRef100_B8JEQ3 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter
dehalogenans 2CP-1 RepID=B8JEQ3_ANAD2
Length = 300
Score = 58.2 bits (139), Expect = 3e-07
Identities = 40/114 (35%), Positives = 56/114 (49%)
Frame = +1
Query: 31 ASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*ILPK 210
A + +FSFEFFPPKT+DGV L E ++ + P+ + G R ++ +
Sbjct: 10 ARERGEPIFSFEFFPPKTDDGVRGLFETVEALRPLGPAYVSVTYGAGGSTRAKTIELVKR 69
Query: 211 RCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFV 372
R V + DE + L+ + G+QNVLALRGDPP GQ FV
Sbjct: 70 LKRDAEVEAMAHVTCVGASRDE-IAAVLDEVAEAGIQNVLALRGDPPRGQGGFV 122
[111][TOP]
>UniRef100_Q6BM19 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=Q6BM19_DEBHA
Length = 642
Score = 58.2 bits (139), Expect = 3e-07
Identities = 42/120 (35%), Positives = 59/120 (49%), Gaps = 6/120 (5%)
Frame = +1
Query: 31 ASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*IL-- 204
A P+ SFEFFPPKT+ G NLL R++RM A +P + W L
Sbjct: 10 ALKPHERFVSFEFFPPKTDTGFRNLLARLNRMSALNPL---FITVTWGAGGSTSEKSLDL 66
Query: 205 ----PKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFV 372
K + V CT+ E +D+ALE K G++N+LALRGDPP ++ ++
Sbjct: 67 AATCQKEIGLTTVLHLTCTN----TNKEIIDNALEKAKEQGIRNILALRGDPPRTEEYWI 122
[112][TOP]
>UniRef100_C7GU28 Met12p n=2 Tax=Saccharomyces cerevisiae RepID=C7GU28_YEAS2
Length = 657
Score = 58.2 bits (139), Expect = 3e-07
Identities = 44/122 (36%), Positives = 59/122 (48%), Gaps = 3/122 (2%)
Frame = +1
Query: 7 IEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRG 186
I ++ A AS S EFFPPKTE G NL+ERM RM A P + G
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 187 ---M*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHG 357
+ + IP CT+ + +DDAL+ + G++N+LALRGDPP G
Sbjct: 59 KTLALASLAQQTLNIPVCMHLTCTNTDKAI----IDDALDRCYNAGIRNILALRGDPPIG 114
Query: 358 QD 363
+D
Sbjct: 115 ED 116
[113][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 58.2 bits (139), Expect = 3e-07
Identities = 47/123 (38%), Positives = 60/123 (48%), Gaps = 8/123 (6%)
Frame = +1
Query: 7 IEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRG 186
+++ H+AA S P FSFEFF PKT GV NL +RMDRM +P + W N G
Sbjct: 7 LDQAHKAAHSPP--ATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDI---TW--NAG 59
Query: 187 M*H*ILPKRCRIP*VWKP*CTSPAPT--------MPDEKMDDALETIKSNGLQNVLALRG 342
L V+ T T M E +D+AL+ +G QN+LALRG
Sbjct: 60 GRSSTLTNEM----VYTAQSTLGLETCMHLTCTNMKVELIDEALDKAYKSGCQNILALRG 115
Query: 343 DPP 351
DPP
Sbjct: 116 DPP 118
[114][TOP]
>UniRef100_B5VTD9 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VTD9_YEAS6
Length = 657
Score = 58.2 bits (139), Expect = 3e-07
Identities = 44/122 (36%), Positives = 59/122 (48%), Gaps = 3/122 (2%)
Frame = +1
Query: 7 IEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRG 186
I ++ A AS S EFFPPKTE G NL+ERM RM A P + G
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 187 ---M*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHG 357
+ + IP CT+ + +DDAL+ + G++N+LALRGDPP G
Sbjct: 59 KTLALASLAQQTLNIPVCMHLTCTNTDKAI----IDDALDRCYNAGIRNILALRGDPPIG 114
Query: 358 QD 363
+D
Sbjct: 115 ED 116
[115][TOP]
>UniRef100_B3LL40 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LL40_YEAS1
Length = 657
Score = 58.2 bits (139), Expect = 3e-07
Identities = 44/122 (36%), Positives = 59/122 (48%), Gaps = 3/122 (2%)
Frame = +1
Query: 7 IEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRG 186
I ++ A AS S EFFPPKTE G NL+ERM RM A P + G
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 187 ---M*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHG 357
+ + IP CT+ + +DDAL+ + G++N+LALRGDPP G
Sbjct: 59 KTLALASLAQQTLNIPVCMHLTCTNTDKAI----IDDALDRCYNAGIRNILALRGDPPIG 114
Query: 358 QD 363
+D
Sbjct: 115 ED 116
[116][TOP]
>UniRef100_A6ZWM3 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae YJM789 RepID=A6ZWM3_YEAS7
Length = 441
Score = 58.2 bits (139), Expect = 3e-07
Identities = 44/122 (36%), Positives = 59/122 (48%), Gaps = 3/122 (2%)
Frame = +1
Query: 7 IEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRG 186
I ++ A AS S EFFPPKTE G NL+ERM RM A P + G
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 187 ---M*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHG 357
+ + IP CT+ + +DDAL+ + G++N+LALRGDPP G
Sbjct: 59 KTLALASLAQQTLNIPVCMHLTCTNTDKAI----IDDALDRCYNAGIRNILALRGDPPIG 114
Query: 358 QD 363
+D
Sbjct: 115 ED 116
[117][TOP]
>UniRef100_A3LW82 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LW82_PICST
Length = 635
Score = 58.2 bits (139), Expect = 3e-07
Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 4/116 (3%)
Frame = +1
Query: 28 AASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*ILP 207
AA P+ SFEFFPPKT+ G NLL R++RM A +P + G + L
Sbjct: 9 AALGPDEKFISFEFFPPKTDSGFRNLLARLNRMSALNPLFITVTWGAGG-STSEKSLDLA 67
Query: 208 KRCR----IP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQD 363
C+ + + CT+ E +D+AL+ K +G++N+LALRGDPP ++
Sbjct: 68 ATCQNDLGLTTILHLTCTN----TNKEIIDEALKRAKESGIRNILALRGDPPRAEE 119
[118][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 43.9 bits (102), Expect(2) = 3e-07
Identities = 37/117 (31%), Positives = 55/117 (47%), Gaps = 7/117 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T G VNL+ R DRM + P V + G ++ I+
Sbjct: 54 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVNF 113
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEG 384
C + + C + E + L+ K GL+N++ALRGDP G++ + EG
Sbjct: 114 CGLETLLHMTCCN----QTKEDITKHLQKAKRLGLKNIMALRGDPT-GEEWEEEAEG 165
Score = 33.9 bits (76), Expect(2) = 3e-07
Identities = 16/26 (61%), Positives = 18/26 (69%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A DLVKHIR + DYF I +AGY
Sbjct: 166 FNYAVDLVKHIRHEFEDYFDICVAGY 191
[119][TOP]
>UniRef100_C1XWC8 Methylenetetrahydrofolate reductase n=1 Tax=Meiothermus silvanus
DSM 9946 RepID=C1XWC8_9DEIN
Length = 294
Score = 57.8 bits (138), Expect = 4e-07
Identities = 43/126 (34%), Positives = 63/126 (50%), Gaps = 1/126 (0%)
Frame = +1
Query: 13 KIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM* 192
KIH A P + +FSFEFFPPKTE+G L + + P+ + G RG
Sbjct: 2 KIHTQFA--PGKPLFSFEFFPPKTEEGEAQLFRTLHILKPLQPAFVSVTYGAGGSARGKT 59
Query: 193 H*ILPKRCR-IP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKF 369
+ + R + T T E++ + LE ++ G +N++A+RGDPP GQ +F
Sbjct: 60 VEWVERIKREVGLEVMAHLTCVGATR--EEIGEVLEQLRQVGAENLMAVRGDPPKGQREF 117
Query: 370 VQVEGG 387
VEGG
Sbjct: 118 RPVEGG 123
[120][TOP]
>UniRef100_A5DE00 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DE00_PICGU
Length = 642
Score = 57.8 bits (138), Expect = 4e-07
Identities = 43/126 (34%), Positives = 61/126 (48%), Gaps = 6/126 (4%)
Frame = +1
Query: 4 VIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINR 183
V++KI+ D SFEFFPPKT+ G NLL R+ RM A +P + W
Sbjct: 3 VVQKINSLGPQDR---FISFEFFPPKTDTGFRNLLARLHRMSALNPL---FITVTWGAGG 56
Query: 184 GM*H*IL------PKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGD 345
L K + V CT+ + +D+AL+ K NG++N+LALRGD
Sbjct: 57 STSEKSLDLAITCQKELGLTTVLHLTCTNTNKDI----IDNALQRAKENGIRNILALRGD 112
Query: 346 PPHGQD 363
PP ++
Sbjct: 113 PPRTEE 118
[121][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 42.0 bits (97), Expect(2) = 4e-07
Identities = 37/118 (31%), Positives = 56/118 (47%), Gaps = 7/118 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T G VNL+ R DRM + P + + G ++ ++
Sbjct: 64 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY 123
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
C + + C + +K+ L K GL+N++ALRGDP G D + + EGG
Sbjct: 124 CGLESILHLTCCN----QTKDKITGYLGKAKHLGLKNIMALRGDPV-GAD-WEEEEGG 175
Score = 35.4 bits (80), Expect(2) = 4e-07
Identities = 16/26 (61%), Positives = 19/26 (73%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A DLVKHIR++ DYF I +AGY
Sbjct: 176 FNYAVDLVKHIRSEFDDYFDICVAGY 201
[122][TOP]
>UniRef100_B6QFH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QFH8_PENMQ
Length = 710
Score = 57.0 bits (136), Expect = 6e-07
Identities = 45/125 (36%), Positives = 64/125 (51%), Gaps = 4/125 (3%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSVL*YYVGCWRI 177
K+ EKI AA P+ FS EFFPPKT+ G VNL R++RM A P + G
Sbjct: 3 KITEKI---AALPPDSNYFSLEFFPPKTQMGSVNLQARLERMAQALRPLFVTVTWGAGGT 59
Query: 178 NRGM---*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDP 348
I ++ ++ CT+ M +D+ALE K+ G++N+LALRGDP
Sbjct: 60 TAAKSLELAEICQRQLQLTTCLHLTCTN----MTRSLIDEALEQAKALGIRNILALRGDP 115
Query: 349 PHGQD 363
P ++
Sbjct: 116 PRSEE 120
[123][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 57.0 bits (136), Expect = 6e-07
Identities = 42/121 (34%), Positives = 61/121 (50%), Gaps = 4/121 (3%)
Frame = +1
Query: 1 KVIEKIHEA-AASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRI 177
++ EK+ +A + S P FSFEFF PKT GV NL +RMDRM +P +
Sbjct: 2 RISEKLSQAHSTSSPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGGR 61
Query: 178 NRGM*H*IL---PKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDP 348
+ + + ++ + CT+ M E +D+AL +G QN+LALRGDP
Sbjct: 62 SSSLTNEMVYTAQSTLGLETCMHLTCTN----MKIELIDEALHKAYVSGCQNILALRGDP 117
Query: 349 P 351
P
Sbjct: 118 P 118
[124][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 57.0 bits (136), Expect = 6e-07
Identities = 42/121 (34%), Positives = 62/121 (51%), Gaps = 4/121 (3%)
Frame = +1
Query: 1 KVIEKIHEAAAS-DPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRI 177
K+ +K+ +A +S +P FSFEFF PKT GV NL +RMDRM +P +
Sbjct: 2 KISDKLSQAHSSANPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGGR 61
Query: 178 NRGM*H*IL---PKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDP 348
+ + + ++ + CT+ M E +D+AL +G QN+LALRGDP
Sbjct: 62 SSSLTNEMVYTAQSTLGLETCMHLTCTN----MKVELIDEALHKAFESGCQNILALRGDP 117
Query: 349 P 351
P
Sbjct: 118 P 118
[125][TOP]
>UniRef100_B4D0K5 Methylenetetrahydrofolate reductase n=1 Tax=Chthoniobacter flavus
Ellin428 RepID=B4D0K5_9BACT
Length = 297
Score = 56.6 bits (135), Expect = 8e-07
Identities = 45/125 (36%), Positives = 63/125 (50%), Gaps = 4/125 (3%)
Frame = +1
Query: 25 AAASDPNRVVFSFEFFPPKTEDGVVNLLER-MDRMVAHSPSVL*YYVGCWRINRGM*H*I 201
A A R V S EFFP KTE+G NLLE+ + +++ P+ G R I
Sbjct: 9 AEARLAGRPVLSLEFFPTKTEEGERNLLEKTLPDLMSIKPAFCSVTYGAGGGTRDKTLGI 68
Query: 202 LPKRCR---IP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFV 372
+ + R +P + C + E++ L+ K G+QN+LALRGDPP G D FV
Sbjct: 69 VDRIQRHHNLPAMMHLTCVNSTR----EELGHVLDEAKGRGIQNILALRGDPPSGGD-FV 123
Query: 373 QVEGG 387
+ EGG
Sbjct: 124 KTEGG 128
[126][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 42.4 bits (98), Expect(2) = 9e-07
Identities = 36/117 (30%), Positives = 56/117 (47%), Gaps = 7/117 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T + VNL+ R DRM A P V + G ++ I+
Sbjct: 62 FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY 121
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEG 384
C + + C +++ L+ K GL+N++ALRGDP G++ +V+G
Sbjct: 122 CGLETIVHMTCCH----QTKDEITGHLQKAKRLGLKNIMALRGDPV-GEEWEEEVDG 173
Score = 33.9 bits (76), Expect(2) = 9e-07
Identities = 16/26 (61%), Positives = 18/26 (69%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A DLVKHIR + DYF I +AGY
Sbjct: 174 FNHAVDLVKHIRNEFDDYFDICVAGY 199
[127][TOP]
>UniRef100_UPI000194E904 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH), partial n=1 Tax=Taeniopygia guttata
RepID=UPI000194E904
Length = 345
Score = 42.4 bits (98), Expect(2) = 9e-07
Identities = 36/117 (30%), Positives = 56/117 (47%), Gaps = 7/117 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T + VNL+ R DRM A P V + G ++ I+
Sbjct: 62 FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY 121
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEG 384
C + + C +++ L+ K GL+N++ALRGDP G++ +V+G
Sbjct: 122 CGLETILHMTCCH----QTRDEITGHLQKAKRLGLKNIMALRGDPV-GEEWEEEVDG 173
Score = 33.9 bits (76), Expect(2) = 9e-07
Identities = 16/26 (61%), Positives = 18/26 (69%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A DLVKHIR + DYF I +AGY
Sbjct: 174 FNHAVDLVKHIRNEFDDYFDICVAGY 199
[128][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 56.2 bits (134), Expect = 1e-06
Identities = 42/121 (34%), Positives = 61/121 (50%), Gaps = 4/121 (3%)
Frame = +1
Query: 1 KVIEKIHEA-AASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRI 177
++ EK+ +A + S P FSFEFF PKT GV NL +RMDRM +P +
Sbjct: 2 RISEKLLQAHSTSSPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGGR 61
Query: 178 NRGM*H*IL---PKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDP 348
+ + + ++ + CT+ M E +D+AL +G QN+LALRGDP
Sbjct: 62 SSSLTNEMVYTAQSTLGLETCMHLTCTN----MKIELIDEALHKAYVSGCQNILALRGDP 117
Query: 349 P 351
P
Sbjct: 118 P 118
[129][TOP]
>UniRef100_A7HDS2 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter sp.
Fw109-5 RepID=A7HDS2_ANADF
Length = 300
Score = 56.2 bits (134), Expect = 1e-06
Identities = 39/113 (34%), Positives = 55/113 (48%)
Frame = +1
Query: 31 ASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*ILPK 210
A + VFSFEFFPPKT+DGV L E ++ + +P+ + G R L K
Sbjct: 10 ARERGEPVFSFEFFPPKTDDGVRQLFETVEALRPLAPAYVSVTYGAGGSTRQR-TLELVK 68
Query: 211 RCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKF 369
R + + E++ L+ + G+QNVLALRGDPP G+ F
Sbjct: 69 RLKRDTEVEAMAHLTCVGASREELAAVLDELAEAGIQNVLALRGDPPRGETSF 121
[130][TOP]
>UniRef100_Q08QG9 Methylenetetrahydrofolate reductase n=1 Tax=Stigmatella aurantiaca
DW4/3-1 RepID=Q08QG9_STIAU
Length = 327
Score = 56.2 bits (134), Expect = 1e-06
Identities = 36/117 (30%), Positives = 57/117 (48%)
Frame = +1
Query: 37 DPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*ILPKRC 216
+P+ FSFEFFPPKT++G NLL+ ++ + P + G R ++ +
Sbjct: 45 NPSNPCFSFEFFPPKTDEGTENLLKTVEELAPLEPGFVSVTYGAGGSTREKTLGLVTRIK 104
Query: 217 RIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
+ + + DE + + L+ +++ L NVL LRGDPP GQ F GG
Sbjct: 105 QTTGIESMAHLTCVGHTRDE-LREVLQQLEAAKLDNVLVLRGDPPRGQTTFAPTPGG 160
[131][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 40.4 bits (93), Expect(2) = 1e-06
Identities = 15/34 (44%), Positives = 25/34 (73%)
Frame = +1
Query: 280 MDDALETIKSNGLQNVLALRGDPPHGQDKFVQVE 381
+D L+T K G++N+LALRGDPP G++ ++ +
Sbjct: 153 LDQTLDTAKRLGIKNILALRGDPPRGEEYWIAAD 186
Score = 35.4 bits (80), Expect(2) = 1e-06
Identities = 15/26 (57%), Positives = 20/26 (76%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A DLV++IR +HG+YF I +AGY
Sbjct: 189 FQHATDLVRYIRQRHGNYFCIGVAGY 214
[132][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
RepID=A8PV87_BRUMA
Length = 656
Score = 35.4 bits (80), Expect(4) = 1e-06
Identities = 15/29 (51%), Positives = 18/29 (62%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP 141
FS EFFPPKT + V N R+DR +P
Sbjct: 71 FSLEFFPPKTTNSVANFFARLDRFREGNP 99
Score = 28.5 bits (62), Expect(4) = 1e-06
Identities = 13/20 (65%), Positives = 16/20 (80%)
Frame = +1
Query: 292 LETIKSNGLQNVLALRGDPP 351
LE K+ GL+N+LALRGD P
Sbjct: 154 LEQSKALGLKNILALRGDLP 173
Score = 27.7 bits (60), Expect(4) = 1e-06
Identities = 11/23 (47%), Positives = 16/23 (69%)
Frame = +2
Query: 398 ARDLVKHIRAKHGDYFGITIAGY 466
A DL++ I+ ++ DYF I AGY
Sbjct: 186 ALDLIRWIKEEYNDYFTIACAGY 208
Score = 21.9 bits (45), Expect(4) = 1e-06
Identities = 6/10 (60%), Positives = 10/10 (100%)
Frame = +3
Query: 228 GVETMMHLTC 257
G++TM+H+TC
Sbjct: 133 GMDTMLHITC 142
[133][TOP]
>UniRef100_Q2ILB5 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter
dehalogenans 2CP-C RepID=Q2ILB5_ANADE
Length = 300
Score = 55.8 bits (133), Expect = 1e-06
Identities = 39/114 (34%), Positives = 54/114 (47%)
Frame = +1
Query: 31 ASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*ILPK 210
A + +FSFEFFPPKT+DGV L E ++ + P+ + G R L K
Sbjct: 10 ARERGEPIFSFEFFPPKTDDGVRGLFETVEALRPLGPAYVSVTYGAGGSTRAK-TIDLVK 68
Query: 211 RCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFV 372
R + + E++ L+ + G+QNVLALRGD P GQ FV
Sbjct: 69 RLKRDAEVEAMAHVTCVGASREEIAAVLDEVADAGIQNVLALRGDAPRGQSAFV 122
[134][TOP]
>UniRef100_Q6FNS2 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FNS2_CANGA
Length = 645
Score = 55.8 bits (133), Expect = 1e-06
Identities = 40/112 (35%), Positives = 55/112 (49%), Gaps = 6/112 (5%)
Frame = +1
Query: 34 SDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H------ 195
SD + + S EFFPPKTE G NLLERM+RM A P + W
Sbjct: 8 SDRDGPLISLEFFPPKTESGKRNLLERMERMSALDPL---FITVTWGAGGSTSEKTLELA 64
Query: 196 *ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
I + +P CT+ T+ + +AL+ +S G++N+LALRGD P
Sbjct: 65 QIAQRDLNVPICMHLTCTNMDTTL----IKEALDACRSYGIKNILALRGDAP 112
[135][TOP]
>UniRef100_Q5A5S8 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5A5S8_CANAL
Length = 640
Score = 55.8 bits (133), Expect = 1e-06
Identities = 42/118 (35%), Positives = 61/118 (51%), Gaps = 6/118 (5%)
Frame = +1
Query: 28 AASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSP--SVL*YYVGCWRINRGM*H*I 201
A+ P+ SFEFFPPKT+ G NLL R++RM A +P + + G + +
Sbjct: 9 ASLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFVTVTWGAGGSTSEKSL---D 65
Query: 202 LPKRCR----IP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQD 363
L C+ I V CT+ E +D AL K+ G++N+LALRGDPP ++
Sbjct: 66 LAATCQNEIGITTVLHLTCTN----TNKEVIDQALSRAKAAGVRNILALRGDPPRTEE 119
[136][TOP]
>UniRef100_C4YKV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=C4YKV3_CANAL
Length = 640
Score = 55.8 bits (133), Expect = 1e-06
Identities = 42/118 (35%), Positives = 61/118 (51%), Gaps = 6/118 (5%)
Frame = +1
Query: 28 AASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSP--SVL*YYVGCWRINRGM*H*I 201
A+ P+ SFEFFPPKT+ G NLL R++RM A +P + + G + +
Sbjct: 9 ASLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFVTVTWGAGGSTSEKSL---D 65
Query: 202 LPKRCR----IP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQD 363
L C+ I V CT+ E +D AL K+ G++N+LALRGDPP ++
Sbjct: 66 LAATCQNEIGITTVLHLTCTN----TNKEVIDQALSKAKAAGVRNILALRGDPPRTEE 119
[137][TOP]
>UniRef100_B9WCV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WCV3_CANDC
Length = 640
Score = 55.8 bits (133), Expect = 1e-06
Identities = 42/116 (36%), Positives = 59/116 (50%), Gaps = 4/116 (3%)
Frame = +1
Query: 28 AASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*ILP 207
A+ P+ SFEFFPPKT+ G NLL R++RM A +P + G + L
Sbjct: 9 ASLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFITVTWGAGG-STSEKSLDLA 67
Query: 208 KRCR----IP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQD 363
C+ I V CT+ E +D AL K+ G++N+LALRGDPP ++
Sbjct: 68 ATCQNEIGITTVLHLTCTN----TNKEVIDQALSKAKAAGVRNILALRGDPPRTEE 119
[138][TOP]
>UniRef100_Q4Q0B9 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania major
RepID=Q4Q0B9_LEIMA
Length = 309
Score = 55.8 bits (133), Expect = 1e-06
Identities = 39/114 (34%), Positives = 58/114 (50%), Gaps = 7/114 (6%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNIRYCQKDAEYRRCGNHDAP-HLHQRCLMRRWTMLSRP---SSPM 313
F D+TWGAGG T+ +R C KD ++ + D P ++H C ++ +
Sbjct: 50 FLDLTWGAGGRTSGTTMRLC-KDLQH---AHPDTPINMHITCTNTPKGLIKETLEFAKTH 105
Query: 314 ASRMCLLFEVIPHMVRTNSSRSKVD---FACARDLVKHIRAKHGDYFGITIAGY 466
R L P + +VD FACARDLV++IR +GDYF +++AGY
Sbjct: 106 GIRNILALRGDP----PSGEEFQVDPDGFACARDLVRYIRDTYGDYFCVSVAGY 155
[139][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 43.5 bits (101), Expect(2) = 1e-06
Identities = 36/117 (30%), Positives = 54/117 (46%), Gaps = 7/117 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T G VNL+ R DRM + P V + G ++ ++
Sbjct: 54 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMVIASAAVNF 113
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEG 384
C + + C + E + L K GL+N++ALRGDP G++ + EG
Sbjct: 114 CGLETILHMTCCN----QTKEDITKHLHKAKHLGLKNIMALRGDPT-GEEWEEEAEG 165
Score = 32.0 bits (71), Expect(2) = 1e-06
Identities = 15/26 (57%), Positives = 17/26 (65%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A DLV HIR + DYF I +AGY
Sbjct: 166 FNYAVDLVTHIRHEFDDYFDICVAGY 191
[140][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 43.5 bits (101), Expect(2) = 1e-06
Identities = 36/117 (30%), Positives = 54/117 (46%), Gaps = 7/117 (5%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSP---SVL*YYVGCWRINRGM*H*ILPKR---- 213
FS EFFPP+T G VNL+ R DRM + P V + G ++ ++
Sbjct: 54 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMVIASAAVNF 113
Query: 214 CRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEG 384
C + + C + E + L K GL+N++ALRGDP G++ + EG
Sbjct: 114 CGLETILHMTCCN----QTKEDITKHLHKAKHLGLKNIMALRGDPT-GEEWEEEAEG 165
Score = 32.0 bits (71), Expect(2) = 1e-06
Identities = 15/26 (57%), Positives = 17/26 (65%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A DLV HIR + DYF I +AGY
Sbjct: 166 FNYAVDLVTHIRHEFDDYFDICVAGY 191
[141][TOP]
>UniRef100_B0SH77 Methylenetetrahydrofolate reductase n=2 Tax=Leptospira biflexa
serovar Patoc RepID=B0SH77_LEPBA
Length = 295
Score = 55.5 bits (132), Expect = 2e-06
Identities = 36/127 (28%), Positives = 57/127 (44%), Gaps = 3/127 (2%)
Frame = +1
Query: 16 IHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H 195
+H + + SFEFFPPK E+ +L + + +P+ + G R + H
Sbjct: 1 MHISEILGKKQTTISFEFFPPKNEEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRHLTH 60
Query: 196 *ILPK---RCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDK 366
++ K + V C E++ D L+ +G+ N++ALRGDPP GQ
Sbjct: 61 DLVVKLQNETGLTIVSHLTCVGSTK----EEIGDILKRYDKSGIHNIMALRGDPPKGQQD 116
Query: 367 FVQVEGG 387
F Q E G
Sbjct: 117 FQQTENG 123
[142][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 55.5 bits (132), Expect = 2e-06
Identities = 42/121 (34%), Positives = 59/121 (48%), Gaps = 8/121 (6%)
Frame = +1
Query: 55 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*IL------PKRC 216
+SFEFFPPKTE G+ NLL R+DRM + + W N L +
Sbjct: 1 YSFEFFPPKTEPGLDNLLTRIDRMCRRLDPL--FVSITWGSNGSTLSRTLAVASHAQRFA 58
Query: 217 RIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQ--VEGGL 390
+ + CT + E++ L KS+G+ N+LALRGDPP G+ + + V GG
Sbjct: 59 CVDVLLHLSCTG----LTREQIGHVLAMAKSSGVHNILALRGDPPQGKRAWKEGDVSGGE 114
Query: 391 C 393
C
Sbjct: 115 C 115
[143][TOP]
>UniRef100_Q6CEM7 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CEM7_YARLI
Length = 625
Score = 55.5 bits (132), Expect = 2e-06
Identities = 38/117 (32%), Positives = 57/117 (48%), Gaps = 5/117 (4%)
Frame = +1
Query: 28 AASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSP--SVL*YYVGCWRINRGM*H*I 201
A P+ FS EFFPPKT++G+ N R+ RM A P + + G + +
Sbjct: 9 AGLKPDEKFFSLEFFPPKTQNGMANFRARLARMAALKPLFITITWGAGGSTAKKSL---D 65
Query: 202 LPKRCR---IP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQD 363
+ C+ + CT+ P + +D ALE G+ N+LALRGDPP G++
Sbjct: 66 IASECQSMGLDVCLHLTCTNMDPAL----IDQALEAASKAGICNILALRGDPPRGEE 118
[144][TOP]
>UniRef100_A5DZ35 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DZ35_LODEL
Length = 622
Score = 55.5 bits (132), Expect = 2e-06
Identities = 39/114 (34%), Positives = 56/114 (49%), Gaps = 6/114 (5%)
Frame = +1
Query: 40 PNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*IL----- 204
P+ SFEFF PKT+ G NLL R++R++A +P + W L
Sbjct: 13 PDEKFISFEFFSPKTDSGFRNLLARLNRLLAFNPL---FITVTWGAGGSTSEKSLDLAAT 69
Query: 205 -PKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQD 363
+ I V CT+ E +D AL K+NG++N+LALRGDPP ++
Sbjct: 70 CQNKIGINTVLHLTCTN----TDKEIIDSALARAKANGIRNILALRGDPPRTEE 119
[145][TOP]
>UniRef100_Q9N0Y5 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Sus scrofa
RepID=Q9N0Y5_PIG
Length = 183
Score = 39.7 bits (91), Expect(3) = 2e-06
Identities = 16/26 (61%), Positives = 21/26 (80%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F+ A DLVKHIR++ GDYF + +AGY
Sbjct: 62 FSYAADLVKHIRSEFGDYFDVCVAGY 87
Score = 29.6 bits (65), Expect(3) = 2e-06
Identities = 17/38 (44%), Positives = 23/38 (60%)
Frame = +1
Query: 274 EKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
E++ L K GL+N+LALRGDP D++ EGG
Sbjct: 26 EEVTGYLHKAKRLGLKNILALRGDPV--GDQWEAEEGG 61
Score = 24.6 bits (52), Expect(3) = 2e-06
Identities = 9/23 (39%), Positives = 15/23 (65%)
Frame = +3
Query: 201 IAKKMQNTVGVETMMHLTCTNDA 269
IA N G+ET++H+TC + +
Sbjct: 2 IASTAVNYCGLETILHMTCCHQS 24
[146][TOP]
>UniRef100_Q8EY55 Methylenetetrahydrofolate reductase n=1 Tax=Leptospira interrogans
RepID=Q8EY55_LEPIN
Length = 310
Score = 55.1 bits (131), Expect = 2e-06
Identities = 39/115 (33%), Positives = 58/115 (50%), Gaps = 3/115 (2%)
Frame = +1
Query: 52 VFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*ILP---KRCRI 222
V+SFEFFPPKT +G L+E + + +P + G R IL K
Sbjct: 32 VYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDKTVQILSQISKDYSF 91
Query: 223 P*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
P V C ++ + L+ I+S+G+ N++ALRGDPP G+ +F +VE G
Sbjct: 92 PTVSHFTCVGANKN----QILETLKGIRSSGILNLMALRGDPPKGEGEFKKVENG 142
[147][TOP]
>UniRef100_Q75G11 Methylenetetrahydrofolate reductase n=2 Tax=Leptospira interrogans
RepID=Q75G11_LEPIC
Length = 310
Score = 55.1 bits (131), Expect = 2e-06
Identities = 39/115 (33%), Positives = 58/115 (50%), Gaps = 3/115 (2%)
Frame = +1
Query: 52 VFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*ILP---KRCRI 222
V+SFEFFPPKT +G L+E + + +P + G R IL K
Sbjct: 32 VYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDKTVQILSQISKDYSF 91
Query: 223 P*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
P V C ++ + L+ I+S+G+ N++ALRGDPP G+ +F +VE G
Sbjct: 92 PTVSHFTCVGANKN----QILETLKGIRSSGILNLMALRGDPPKGEGEFKKVENG 142
[148][TOP]
>UniRef100_B8BVS6 Methylenetetrahydrofolate reductase n=1 Tax=Thalassiosira
pseudonana CCMP1335 RepID=B8BVS6_THAPS
Length = 383
Score = 55.1 bits (131), Expect = 2e-06
Identities = 39/131 (29%), Positives = 60/131 (45%), Gaps = 6/131 (4%)
Frame = +1
Query: 13 KIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM* 192
KI + D S E+FPP+T+ GV NL RMDRM+ ++ ++ Y W
Sbjct: 12 KIIDLLQRDTEIAHVSLEYFPPRTDQGVKNLHARMDRMLVNTNAL--YTDMTWGAGGSTA 69
Query: 193 H*ILP------KRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPH 354
L K + + P + + DAL+ G++N++ALRGDPP
Sbjct: 70 DLSLELALHAHKTGHVSNMHLTCTNMEKDGDPVKAVHDALQQAYDGGIRNIVALRGDPPE 129
Query: 355 GQDKFVQVEGG 387
G+ ++ EGG
Sbjct: 130 GEKEWTATEGG 140
[149][TOP]
>UniRef100_B8MDD4 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8MDD4_TALSN
Length = 713
Score = 55.1 bits (131), Expect = 2e-06
Identities = 43/124 (34%), Positives = 62/124 (50%), Gaps = 3/124 (2%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNL---LERMDRMVAHSPSVL*YYVGCW 171
K+ EKI AA P FS EFFPPKT+ G VNL LERM +++ + + G
Sbjct: 3 KITEKI---AALPPGSNYFSLEFFPPKTQMGSVNLQARLERMAQVLRPLFVTVTWGAGGT 59
Query: 172 RINRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
+ + L + C+ M +D+ALE K+ G++N+LALRGDPP
Sbjct: 60 TAAKSL---ELAEICQRQLQLTTCLHLTCTNMTRSLIDEALEQAKALGIKNILALRGDPP 116
Query: 352 HGQD 363
++
Sbjct: 117 RSEE 120
[150][TOP]
>UniRef100_A7TRT4 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TRT4_VANPO
Length = 645
Score = 54.7 bits (130), Expect = 3e-06
Identities = 42/105 (40%), Positives = 55/105 (52%), Gaps = 3/105 (2%)
Frame = +1
Query: 58 SFEFFPPKTEDGVVNLLERMDRMVAHSPS--VL*YYVGCWRINRGM*H*ILPKRC-RIP* 228
S EFFPPKTE G NLLERM RM A P + + G + + L + +
Sbjct: 17 SLEFFPPKTEIGKRNLLERMGRMSAMDPLFVTVTWGAGGTTAEKTLELATLAENSLNLNV 76
Query: 229 VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQD 363
CT+ M +D+ALE K G++N+LALRGDPP G+D
Sbjct: 77 CIHLTCTN----MSRGIIDEALEACKKIGIRNILALRGDPPIGED 117
[151][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 54.3 bits (129), Expect = 4e-06
Identities = 44/128 (34%), Positives = 64/128 (50%), Gaps = 7/128 (5%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYV------ 162
K+ +KI AA PN FS EFFPPKT+ G NL R++RM S ++ +V
Sbjct: 3 KITDKI---AALPPNENYFSLEFFPPKTQMGFSNLQARLERM---SQALRPLFVTVTWGA 56
Query: 163 -GCWRINRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALR 339
G I ++ ++ CT+ M +D+ALE K G++N+LALR
Sbjct: 57 GGSTAARSLELAEICQRQLQLTTCLHLTCTN----MSRALIDEALEEAKVLGIRNILALR 112
Query: 340 GDPPHGQD 363
GDPP ++
Sbjct: 113 GDPPRSEE 120
[152][TOP]
>UniRef100_C8V780 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5AU15] n=2 Tax=Emericella
nidulans RepID=C8V780_EMENI
Length = 684
Score = 54.3 bits (129), Expect = 4e-06
Identities = 44/123 (35%), Positives = 60/123 (48%), Gaps = 4/123 (3%)
Frame = +1
Query: 7 IEKI-HEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSP--SVL*YYVGCWR 174
+EKI H+ AA P FS EFFPPKT+ G NL R++RM A P + + G
Sbjct: 1 MEKITHKIAALPPGANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST 60
Query: 175 INRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPH 354
R + L + C+ M +D ALE K G++N+LALRGDPP
Sbjct: 61 AARSL---ELAEICQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPR 117
Query: 355 GQD 363
++
Sbjct: 118 SEE 120
[153][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 54.3 bits (129), Expect = 4e-06
Identities = 44/128 (34%), Positives = 64/128 (50%), Gaps = 7/128 (5%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYV------ 162
K+ +KI AA PN FS EFFPPKT+ G NL R++RM S ++ +V
Sbjct: 3 KITDKI---AALPPNENYFSLEFFPPKTQMGFSNLQARLERM---SQALRPLFVTVTWGA 56
Query: 163 -GCWRINRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALR 339
G I ++ ++ CT+ M +D+ALE K G++N+LALR
Sbjct: 57 GGSTAARSLELAEICQRQLQLTTCLHLTCTN----MSRALIDEALEEAKVLGIRNILALR 112
Query: 340 GDPPHGQD 363
GDPP ++
Sbjct: 113 GDPPRSEE 120
[154][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1CZX0_NEOFI
Length = 716
Score = 54.3 bits (129), Expect = 4e-06
Identities = 44/128 (34%), Positives = 64/128 (50%), Gaps = 7/128 (5%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYV------ 162
K+ +KI AA PN FS EFFPPKT+ G NL R++RM S ++ +V
Sbjct: 30 KITDKI---AALPPNENYFSLEFFPPKTQMGFSNLQARLERM---SQALRPLFVTVTWGA 83
Query: 163 -GCWRINRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALR 339
G I ++ ++ CT+ M +D+ALE K G++N+LALR
Sbjct: 84 GGSTAARSLELAEICQRQLQLTTCLHLTCTN----MSRALIDEALEEAKVLGIRNILALR 139
Query: 340 GDPPHGQD 363
GDPP ++
Sbjct: 140 GDPPRSEE 147
[155][TOP]
>UniRef100_C4R2L4 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2L4_PICPG
Length = 596
Score = 53.9 bits (128), Expect = 5e-06
Identities = 40/120 (33%), Positives = 60/120 (50%), Gaps = 3/120 (2%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRIN 180
K+I+KI E +SFEFFPPKT++G+ NLL R+ RM +P + G
Sbjct: 3 KIIDKIKELKGEP----FYSFEFFPPKTDNGLRNLLARLGRMSMLNPLFVTVTWGAGGTT 58
Query: 181 RGM*H*I---LPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
+ K + CT+ + + +D+AL+ NG++N+LALRGDPP
Sbjct: 59 SSKTLDLAITCQKDLDLTTCIHLTCTNTSKKL----IDNALKAAYDNGIKNILALRGDPP 114
[156][TOP]
>UniRef100_UPI00005884BD PREDICTED: similar to Mthfr-prov protein, partial n=1
Tax=Strongylocentrotus purpuratus RepID=UPI00005884BD
Length = 326
Score = 40.8 bits (94), Expect(2) = 5e-06
Identities = 43/142 (30%), Positives = 62/142 (43%), Gaps = 8/142 (5%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSP-SVL*YY------ 159
++ EKI AS FS EFFPP+T G VNL+ R M V+ Y
Sbjct: 57 RLSEKIANRIASKDRW--FSLEFFPPRTASGAVNLVGRYVHMGGGGEIKVMEMYYPWGGG 114
Query: 160 -VGCWRINRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLAL 336
G +++ + +L C + + C S + E + LE K G++N+LAL
Sbjct: 115 GAGEEQVSMEIARTML-NYCGLDTMLHMCCVSQSA----EVITRHLEWAKECGIRNILAL 169
Query: 337 RGDPPHGQDKFVQVEGGLCLCT 402
RGD P D++ GG T
Sbjct: 170 RGDVPGHTDEWEPTPGGFNYAT 191
Score = 32.7 bits (73), Expect(2) = 5e-06
Identities = 16/26 (61%), Positives = 17/26 (65%)
Frame = +2
Query: 389 FACARDLVKHIRAKHGDYFGITIAGY 466
F A DLVKHIR GD F I +AGY
Sbjct: 187 FNYATDLVKHIRKVFGDDFVIAVAGY 212
[157][TOP]
>UniRef100_Q6CR34 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CR34_KLULA
Length = 649
Score = 53.5 bits (127), Expect = 7e-06
Identities = 37/105 (35%), Positives = 53/105 (50%), Gaps = 3/105 (2%)
Frame = +1
Query: 58 SFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM---*H*ILPKRCRIP* 228
S EFFPPKTE G NLL RM+RM A +P + G I + +P
Sbjct: 27 SLEFFPPKTEPGKRNLLARMERMCALNPLFITVTWAAGGTTAGKTLELATIAQRELNVPV 86
Query: 229 VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQD 363
CT+ M + +D+AL+ + ++N+LALRGDP G++
Sbjct: 87 CMHLTCTN----MNKDIIDEALKAARDADIRNILALRGDPAIGEE 127
[158][TOP]
>UniRef100_Q2UA39 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus oryzae
RepID=Q2UA39_ASPOR
Length = 690
Score = 53.5 bits (127), Expect = 7e-06
Identities = 43/124 (34%), Positives = 61/124 (49%), Gaps = 3/124 (2%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSP--SVL*YYVGCW 171
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P + + G
Sbjct: 3 KITDKI---AALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGS 59
Query: 172 RINRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
R + L + C+ M +D+ALE K G++N+LALRGDPP
Sbjct: 60 TAQRSL---ELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPP 116
Query: 352 HGQD 363
++
Sbjct: 117 RSEE 120
[159][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 53.5 bits (127), Expect = 7e-06
Identities = 45/129 (34%), Positives = 58/129 (44%), Gaps = 12/129 (9%)
Frame = +1
Query: 1 KVIEKIHEA----AASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGC 168
K+ +K+ +A FSFEFF PKT G+ NL +RMDRM +P +
Sbjct: 2 KITDKLQQAHSCKVGGSAPPATFSFEFFVPKTSQGLQNLYDRMDRMYDLNPIFIDI---T 58
Query: 169 WRINRGM*H*ILPKRCRIP*VWKP*CTSPAPT--------MPDEKMDDALETIKSNGLQN 324
W N G L V+ T T MP +D+ALE +G QN
Sbjct: 59 W--NAGGRSSTLTNEM----VYTAQSTLGLETCMHLTCTNMPVSLIDEALEKAFKSGCQN 112
Query: 325 VLALRGDPP 351
+LALRGDPP
Sbjct: 113 ILALRGDPP 121
[160][TOP]
>UniRef100_B8NQE8 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus flavus
NRRL3357 RepID=B8NQE8_ASPFN
Length = 738
Score = 53.5 bits (127), Expect = 7e-06
Identities = 43/124 (34%), Positives = 61/124 (49%), Gaps = 3/124 (2%)
Frame = +1
Query: 1 KVIEKIHEAAASDPNRVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSP--SVL*YYVGCW 171
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P + + G
Sbjct: 51 KITDKI---AALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGS 107
Query: 172 RINRGM*H*ILPKRCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPP 351
R + L + C+ M +D+ALE K G++N+LALRGDPP
Sbjct: 108 TAQRSL---ELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPP 164
Query: 352 HGQD 363
++
Sbjct: 165 RSEE 168
[161][TOP]
>UniRef100_A4IC95 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania infantum
RepID=A4IC95_LEIIN
Length = 309
Score = 53.5 bits (127), Expect = 7e-06
Identities = 39/112 (34%), Positives = 57/112 (50%), Gaps = 5/112 (4%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNIRYCQKDAEYRRCGNHDAP-HLHQRCLMRRWTMLSRP---SSPM 313
F D+TWGAGG T+ +R C KD ++ D P ++H C +++ +
Sbjct: 50 FLDLTWGAGGRTSDTTMRLC-KDLQH---AYPDTPINMHITCTNTPKGLINEALDFAKTH 105
Query: 314 ASRMCLLFEVIPHMVRTNSSRSKVD-FACARDLVKHIRAKHGDYFGITIAGY 466
R L P R R+ D FACARDLV++I +GDYF +++AGY
Sbjct: 106 GIRNILALRGDPP--RGEEFRADPDGFACARDLVRYIHDTYGDYFCVSVAGY 155
[162][TOP]
>UniRef100_B3QV58 Methylenetetrahydrofolate reductase n=1 Tax=Chloroherpeton
thalassium ATCC 35110 RepID=B3QV58_CHLT3
Length = 294
Score = 53.1 bits (126), Expect = 9e-06
Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 3/119 (2%)
Frame = +1
Query: 40 PNRVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSVL*YYVGCWRINRGM*H*I---LPK 210
P++ FSFEF+PPK ++ L + ++ +P+ + G R H + + K
Sbjct: 9 PDKTQFSFEFYPPKKDEEWEKLFFHISELMPMNPAYVSVTYGAGGSTRDKTHNLVVRISK 68
Query: 211 RCRIP*VWKP*CTSPAPTMPDEKMDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 387
IP V C + + ++ LE NG+ N+LALRGDPP G F + G
Sbjct: 69 ETNIPVVSHLTCVGSSKS----EIHTILERYAENGITNILALRGDPPKGSTTFEKPADG 123
[163][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 53.1 bits (126), Expect = 9e-06
Identities = 39/117 (33%), Positives = 52/117 (44%), Gaps = 10/117 (8%)
Frame = +2
Query: 146 FCDITWGAGGSTAACNIRY---CQKDAEYRRCGNHDAPHLHQRCLMRRWTMLSRP---SS 307
F +TWGAGGSTAA ++ CQ+ C LH C T++ +
Sbjct: 49 FVTVTWGAGGSTAARSLELAEICQRQLGLTTC-------LHLTCTNMNRTLIDEALEETK 101
Query: 308 PMASRMCLLFEVIPHMVRT----NSSRSKVDFACARDLVKHIRAKHGDYFGITIAGY 466
+ R L P S DF+ A DLV++IR K+GDYF I +AGY
Sbjct: 102 ALGIRNILALRGDPPRSEEYNIDGEDDSNKDFSHAVDLVRYIRKKYGDYFCIGVAGY 158