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[1][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 124 bits (311), Expect = 4e-27
Identities = 65/106 (61%), Positives = 75/106 (70%)
Frame = -2
Query: 540 GFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSAL 361
GFCKTKIPAE+ AALEPIKDNEEAV+AYGIHLGTEMCKKI+AHG KTLHLYTLN+EKSAL
Sbjct: 250 GFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKIMAHGIKTLHLYTLNMEKSAL 309
Query: 360 AIPKEPWLN*RDQHTSDTPCQCYSGLKKMVRIKRGQRKTWWFKWPK 223
AI L + + P + + R+K G R +W PK
Sbjct: 310 AILMNLGLIEESKISRPLP---WRPPTNVFRVKEGVRPIFWANRPK 352
[2][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 124 bits (310), Expect = 6e-27
Identities = 66/106 (62%), Positives = 74/106 (69%)
Frame = -2
Query: 540 GFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSAL 361
GFCKTKIPAE+ AALEPIKDNEEAV+AYGIHLGTEMCKKILAHG KTLHLYTLN+EKSAL
Sbjct: 246 GFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSAL 305
Query: 360 AIPKEPWLN*RDQHTSDTPCQCYSGLKKMVRIKRGQRKTWWFKWPK 223
AI L + T P + + R+K R +W PK
Sbjct: 306 AILMNLGLIEESKITRPLP---WRPPTNVFRVKEDVRPIFWANRPK 348
[3][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 122 bits (305), Expect = 2e-26
Identities = 66/106 (62%), Positives = 73/106 (68%)
Frame = -2
Query: 540 GFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSAL 361
GFCKTKIPAE+ AALEPIKDNEEAV+AYGIHLGTEMCKKILAHG KTLHLYTLN+EKSAL
Sbjct: 249 GFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSAL 308
Query: 360 AIPKEPWLN*RDQHTSDTPCQCYSGLKKMVRIKRGQRKTWWFKWPK 223
AI L + T P + + R K R +W PK
Sbjct: 309 AILMNLGLIEESKITRALP---WRPPTNVFRAKEDVRPIFWANRPK 351
[4][TOP]
>UniRef100_C6T731 Methylenetetrahydrofolate reductase n=1 Tax=Glycine max
RepID=C6T731_SOYBN
Length = 344
Score = 121 bits (304), Expect(2) = 2e-26
Identities = 58/62 (93%), Positives = 60/62 (96%)
Frame = -2
Query: 540 GFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSAL 361
GFCKTKIPA+IMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG TLHLYTLN+EKSAL
Sbjct: 236 GFCKTKIPADIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGINTLHLYTLNMEKSAL 295
Query: 360 AI 355
AI
Sbjct: 296 AI 297
Score = 21.2 bits (43), Expect(2) = 2e-26
Identities = 11/22 (50%), Positives = 13/22 (59%)
Frame = -3
Query: 353 LKNLGLIEETSIPRTRPANAIQ 288
L NLGLIEET +A+Q
Sbjct: 298 LMNLGLIEETKFLGPYLGDALQ 319
[5][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 118 bits (296), Expect(2) = 4e-26
Identities = 55/62 (88%), Positives = 60/62 (96%)
Frame = -2
Query: 540 GFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSAL 361
GFCKTKIP+E+ AALEPIKDN+EAVKAYGIHLGTEMCKKILAHG KT+HLYTLN+EKSAL
Sbjct: 235 GFCKTKIPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAHGIKTVHLYTLNMEKSAL 294
Query: 360 AI 355
AI
Sbjct: 295 AI 296
Score = 23.5 bits (49), Expect(2) = 4e-26
Identities = 11/17 (64%), Positives = 12/17 (70%)
Frame = -3
Query: 353 LKNLGLIEETSIPRTRP 303
L NLGLIEE+ I R P
Sbjct: 297 LMNLGLIEESKISRPFP 313
[6][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 118 bits (296), Expect(2) = 4e-26
Identities = 55/62 (88%), Positives = 60/62 (96%)
Frame = -2
Query: 540 GFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSAL 361
GFCKTKIP+E+ AALEPIKDN+EAVKAYGIHLGTEMCKKILAHG KT+HLYTLN+EKSAL
Sbjct: 235 GFCKTKIPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAHGIKTVHLYTLNMEKSAL 294
Query: 360 AI 355
AI
Sbjct: 295 AI 296
Score = 23.5 bits (49), Expect(2) = 4e-26
Identities = 11/17 (64%), Positives = 12/17 (70%)
Frame = -3
Query: 353 LKNLGLIEETSIPRTRP 303
L NLGLIEE+ I R P
Sbjct: 297 LMNLGLIEESKISRPFP 313
[7][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 119 bits (299), Expect = 1e-25
Identities = 56/62 (90%), Positives = 60/62 (96%)
Frame = -2
Query: 540 GFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSAL 361
GFCKTKIP E+MAALEPIKDNEEAVKAYGIHLGTEMCKK+LAHG K+LHLYTLN+EKSAL
Sbjct: 235 GFCKTKIPVEVMAALEPIKDNEEAVKAYGIHLGTEMCKKMLAHGVKSLHLYTLNMEKSAL 294
Query: 360 AI 355
AI
Sbjct: 295 AI 296
[8][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 119 bits (297), Expect = 2e-25
Identities = 65/106 (61%), Positives = 72/106 (67%)
Frame = -2
Query: 540 GFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSAL 361
GFCKTKIPAEI AALEPIKDNEEAVKAYGIHLGTEMCKKILA G KTLHLYTLN+EKSAL
Sbjct: 235 GFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSAL 294
Query: 360 AIPKEPWLN*RDQHTSDTPCQCYSGLKKMVRIKRGQRKTWWFKWPK 223
I L + + P + + R+K R +W PK
Sbjct: 295 GILMNLGLIEESKISRSLP---WRPPTNVFRVKEDVRPIFWANRPK 337
[9][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 119 bits (297), Expect = 2e-25
Identities = 65/106 (61%), Positives = 72/106 (67%)
Frame = -2
Query: 540 GFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSAL 361
GFCKTKIPAEI AALEPIKDNEEAVKAYGIHLGTEMCKKILA G KTLHLYTLN+EKSAL
Sbjct: 235 GFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSAL 294
Query: 360 AIPKEPWLN*RDQHTSDTPCQCYSGLKKMVRIKRGQRKTWWFKWPK 223
I L + + P + + R+K R +W PK
Sbjct: 295 GILMNLGLIEESKISRSLP---WRPPTNVFRVKEDVRPIFWANRPK 337
[10][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 118 bits (296), Expect = 2e-25
Identities = 56/62 (90%), Positives = 59/62 (95%)
Frame = -2
Query: 540 GFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSAL 361
GFCKTKIP+EI AALEPIKDNEEAV+AYGIHLGTEMCKKILAHG KTLHLYTLN+EKSAL
Sbjct: 235 GFCKTKIPSEITAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSAL 294
Query: 360 AI 355
I
Sbjct: 295 GI 296
[11][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 118 bits (295), Expect = 3e-25
Identities = 64/106 (60%), Positives = 73/106 (68%)
Frame = -2
Query: 540 GFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSAL 361
GFCKTKIPAEI AAL+PIKDNEEAVKAYGIHLGTEMCKKILA G KTLHLYTLN+EK+AL
Sbjct: 223 GFCKTKIPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKTAL 282
Query: 360 AIPKEPWLN*RDQHTSDTPCQCYSGLKKMVRIKRGQRKTWWFKWPK 223
AI L + + P + + R+K R +W PK
Sbjct: 283 AILMNLGLIEESKLSRTLP---WRPPTNVFRVKEDVRPIFWANRPK 325
[12][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 113 bits (282), Expect = 1e-23
Identities = 60/106 (56%), Positives = 71/106 (66%)
Frame = -2
Query: 540 GFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSAL 361
GFCKTKIP+EI AAL+PIKDNEEAVK YGIHLGTEMCKKILA G KTLHLYTLN++KSA+
Sbjct: 235 GFCKTKIPSEITAALDPIKDNEEAVKQYGIHLGTEMCKKILATGIKTLHLYTLNMDKSAI 294
Query: 360 AIPKEPWLN*RDQHTSDTPCQCYSGLKKMVRIKRGQRKTWWFKWPK 223
I L + + P + + R+K R +W PK
Sbjct: 295 GILMNLGLIEESKVSRPLP---WRPATNVFRVKEDVRPIFWANRPK 337
[13][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 112 bits (279), Expect = 2e-23
Identities = 59/106 (55%), Positives = 71/106 (66%)
Frame = -2
Query: 540 GFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSAL 361
GFCKTKIP+EI AAL+PIKDNEEAV+ YGIHLGTEMCKKILA G KTLHLYTLN++KSA+
Sbjct: 235 GFCKTKIPSEITAALDPIKDNEEAVRQYGIHLGTEMCKKILATGIKTLHLYTLNMDKSAI 294
Query: 360 AIPKEPWLN*RDQHTSDTPCQCYSGLKKMVRIKRGQRKTWWFKWPK 223
I L + + P + + R+K R +W PK
Sbjct: 295 GILMNLGLIEESKVSRPLP---WRPATNVFRVKEDVRPIFWANRPK 337
[14][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 109 bits (273), Expect = 1e-22
Identities = 51/60 (85%), Positives = 56/60 (93%)
Frame = -2
Query: 534 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 355
CKTK+PAEIMAALEPIKDN+EAV+AYGIHLGTEMCKKILAH +TLHLY+LNLEKS L I
Sbjct: 237 CKTKVPAEIMAALEPIKDNDEAVRAYGIHLGTEMCKKILAHDIRTLHLYSLNLEKSVLGI 296
[15][TOP]
>UniRef100_Q3EAG8 Methylenetetrahydrofolate reductase n=1 Tax=Arabidopsis thaliana
RepID=Q3EAG8_ARATH
Length = 407
Score = 109 bits (272), Expect = 1e-22
Identities = 58/106 (54%), Positives = 69/106 (65%)
Frame = -2
Query: 540 GFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSAL 361
GFCKTKIPAE+ AALEPIKDN+EAVKAYGIH TEMCKKILAHG +LHLYTLN++KSA+
Sbjct: 235 GFCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAI 294
Query: 360 AIPKEPWLN*RDQHTSDTPCQCYSGLKKMVRIKRGQRKTWWFKWPK 223
I L + + P + + R K R +W PK
Sbjct: 295 GILMNLGLIDESKISRSLP---WRRPANVFRTKEDVRPIFWANRPK 337
[16][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=B9DHL6_ARATH
Length = 402
Score = 109 bits (272), Expect = 1e-22
Identities = 58/106 (54%), Positives = 69/106 (65%)
Frame = -2
Query: 540 GFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSAL 361
GFCKTKIPAE+ AALEPIKDN+EAVKAYGIH TEMCKKILAHG +LHLYTLN++KSA+
Sbjct: 45 GFCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAI 104
Query: 360 AIPKEPWLN*RDQHTSDTPCQCYSGLKKMVRIKRGQRKTWWFKWPK 223
I L + + P + + R K R +W PK
Sbjct: 105 GILMNLGLIDESKISRSLP---WRRPANVFRTKEDVRPIFWANRPK 147
[17][TOP]
>UniRef100_Q9SE60-2 Isoform 2 of Methylenetetrahydrofolate reductase 1 n=1
Tax=Arabidopsis thaliana RepID=Q9SE60-2
Length = 421
Score = 109 bits (272), Expect = 1e-22
Identities = 58/106 (54%), Positives = 69/106 (65%)
Frame = -2
Query: 540 GFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSAL 361
GFCKTKIPAE+ AALEPIKDN+EAVKAYGIH TEMCKKILAHG +LHLYTLN++KSA+
Sbjct: 235 GFCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAI 294
Query: 360 AIPKEPWLN*RDQHTSDTPCQCYSGLKKMVRIKRGQRKTWWFKWPK 223
I L + + P + + R K R +W PK
Sbjct: 295 GILMNLGLIDESKISRSLP---WRRPANVFRTKEDVRPIFWANRPK 337
[18][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 109 bits (272), Expect = 1e-22
Identities = 58/106 (54%), Positives = 69/106 (65%)
Frame = -2
Query: 540 GFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSAL 361
GFCKTKIPAE+ AALEPIKDN+EAVKAYGIH TEMCKKILAHG +LHLYTLN++KSA+
Sbjct: 235 GFCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAI 294
Query: 360 AIPKEPWLN*RDQHTSDTPCQCYSGLKKMVRIKRGQRKTWWFKWPK 223
I L + + P + + R K R +W PK
Sbjct: 295 GILMNLGLIDESKISRSLP---WRRPANVFRTKEDVRPIFWANRPK 337
[19][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 108 bits (271), Expect = 2e-22
Identities = 59/104 (56%), Positives = 70/104 (67%)
Frame = -2
Query: 534 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 355
CKTK+PAEIMA LEPIKDN+EAV+AYGIHLGTEMCKKILAH +TLHLY+LNLEKS L I
Sbjct: 237 CKTKVPAEIMATLEPIKDNDEAVRAYGIHLGTEMCKKILAHDIRTLHLYSLNLEKSVLGI 296
Query: 354 PKEPWLN*RDQHTSDTPCQCYSGLKKMVRIKRGQRKTWWFKWPK 223
+ L + T P + + K R K R +W P+
Sbjct: 297 LQNLGLIDFSKVTRPLPWRPPTNSK---RTKEDVRPIFWANRPR 337
[20][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 94.7 bits (234), Expect(2) = 6e-19
Identities = 47/65 (72%), Positives = 54/65 (83%)
Frame = -2
Query: 540 GFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSAL 361
GFCKTKIP+E+ AALEPIKDN+EAVKAYGIHLGTEMCKKILAHG KT L T++L L
Sbjct: 235 GFCKTKIPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAHGIKTFGL-TMDLPWQNL 293
Query: 360 AIPKE 346
+ +E
Sbjct: 294 GLIEE 298
Score = 23.1 bits (48), Expect(2) = 6e-19
Identities = 12/20 (60%), Positives = 13/20 (65%)
Frame = -3
Query: 362 WQYLKNLGLIEETSIPRTRP 303
WQ NLGLIEE+ I R P
Sbjct: 290 WQ---NLGLIEESKISRPFP 306
[21][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 89.0 bits (219), Expect = 2e-16
Identities = 44/63 (69%), Positives = 52/63 (82%), Gaps = 1/63 (1%)
Frame = -2
Query: 540 GFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSA 364
GFCKTK+PAEI ALE IKDN+EAVKAYGI LG MC+++LA G +H+YTLNLEKSA
Sbjct: 229 GFCKTKVPAEISDALEAIKDNDEAVKAYGIDLGVRMCRQLLASGEVPGVHMYTLNLEKSA 288
Query: 363 LAI 355
+AI
Sbjct: 289 VAI 291
[22][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 71.2 bits (173), Expect = 4e-11
Identities = 45/104 (43%), Positives = 58/104 (55%), Gaps = 1/104 (0%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIP 352
KTK+P IM LEPIKDN+E VK YG+ L EM K++L G + LH YTLNLE+S +
Sbjct: 231 KTKVPQYIMDNLEPIKDNDEEVKKYGVRLCVEMSKRLLDFGVEGLHFYTLNLERSVRKVL 290
Query: 351 KEPWLN*RDQHTSDTP-CQCYSGLKKMVRIKRGQRKTWWFKWPK 223
K L DQ + P Q +G R+K R +W P+
Sbjct: 291 KGLQLVTPDQLSPFLPWAQSAAG----NRLKEEVRPIFWQNRPR 330
[23][TOP]
>UniRef100_A7QB31 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7QB31_VITVI
Length = 93
Score = 70.1 bits (170), Expect = 1e-10
Identities = 33/46 (71%), Positives = 37/46 (80%)
Frame = -2
Query: 540 GFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFK 403
GFCKTK+ A ALEPIKDNE+AV YGIHLGTEMCKK+L +G K
Sbjct: 14 GFCKTKVTA----ALEPIKDNEKAVNTYGIHLGTEMCKKVLGNGIK 55
[24][TOP]
>UniRef100_B7GB47 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B7GB47_PHATR
Length = 376
Score = 67.8 bits (164), Expect = 5e-10
Identities = 31/57 (54%), Positives = 40/57 (70%), Gaps = 1/57 (1%)
Frame = -2
Query: 537 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEK 370
FCKT++P + A +E IKD+ AVKA+G+ G EMC+ +LA G LH YTLNLEK
Sbjct: 310 FCKTRVPETLRARMEAIKDDAAAVKAFGVEFGVEMCRTLLASGHVSVLHFYTLNLEK 366
[25][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 65.5 bits (158), Expect = 2e-09
Identities = 30/62 (48%), Positives = 46/62 (74%), Gaps = 1/62 (1%)
Frame = -2
Query: 537 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSAL 361
+C+ ++P E + LEP+KD+++AV+ G L +MC+KILA G T LHLYT+NLE+++L
Sbjct: 230 WCQVRLPPEFLERLEPVKDDDQAVREIGTVLVADMCRKILASGHVTHLHLYTMNLERASL 289
Query: 360 AI 355
I
Sbjct: 290 MI 291
[26][TOP]
>UniRef100_B8BVS6 Methylenetetrahydrofolate reductase n=1 Tax=Thalassiosira
pseudonana CCMP1335 RepID=B8BVS6_THAPS
Length = 383
Score = 64.3 bits (155), Expect = 5e-09
Identities = 28/64 (43%), Positives = 40/64 (62%)
Frame = -2
Query: 537 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALA 358
FCKT++P + ++ IKD+ +AVK +G+ G E+ + +L G K LH YTLNLEK
Sbjct: 249 FCKTRVPKSLEERMDAIKDDADAVKKFGVEFGAEISRNLLDSGVKILHFYTLNLEKVVYG 308
Query: 357 IPKE 346
I E
Sbjct: 309 ITDE 312
[27][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 63.5 bits (153), Expect = 9e-09
Identities = 31/62 (50%), Positives = 41/62 (66%), Gaps = 1/62 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAI 355
K IP EI +EPIKDN+ A++ YGI L T+MC+ +L G LH+YTLNLE + + I
Sbjct: 245 KLSIPEEIQKVIEPIKDNDAAIRKYGIDLATDMCRTLLNSGKVHGLHMYTLNLETATIQI 304
Query: 354 PK 349
K
Sbjct: 305 LK 306
[28][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 62.4 bits (150), Expect = 2e-08
Identities = 32/64 (50%), Positives = 40/64 (62%), Gaps = 3/64 (4%)
Frame = -2
Query: 537 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTL---HLYTLNLEKS 367
+C +P EI LEPIKD++EAVK G L EMC++ILA + H YTLNLE+S
Sbjct: 253 YCGVSVPDEIWKRLEPIKDDDEAVKEIGCSLAAEMCRQILADPIAKIDGVHFYTLNLERS 312
Query: 366 ALAI 355
A I
Sbjct: 313 ATRI 316
[29][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 62.4 bits (150), Expect = 2e-08
Identities = 26/62 (41%), Positives = 44/62 (70%), Gaps = 1/62 (1%)
Frame = -2
Query: 537 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSAL 361
+C+ +P MA L+P+KD+++AV+ G L +MC+K+L G+ T LH+YT+NLEK+ +
Sbjct: 230 WCQINVPEAFMAKLDPVKDDDQAVREVGTELVAQMCQKLLDSGYVTHLHMYTMNLEKACI 289
Query: 360 AI 355
+
Sbjct: 290 MV 291
[30][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 60.8 bits (146), Expect = 6e-08
Identities = 27/57 (47%), Positives = 37/57 (64%)
Frame = -2
Query: 525 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 355
KIP M L P+KD++E V+ G+ L EMC+K++A G LH YT+NLEK+ I
Sbjct: 231 KIPQHFMDTLVPVKDDDEGVRERGVELIVEMCRKLIASGITRLHFYTMNLEKAVKMI 287
[31][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 60.5 bits (145), Expect = 8e-08
Identities = 29/62 (46%), Positives = 40/62 (64%), Gaps = 1/62 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P EI +EPIKDN+ A++ YGI L MCK++LA G LH YTLN E + + +
Sbjct: 267 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVTMCKELLASGLVPGLHFYTLNREVATMEV 326
Query: 354 PK 349
K
Sbjct: 327 LK 328
[32][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 60.5 bits (145), Expect = 8e-08
Identities = 27/62 (43%), Positives = 43/62 (69%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIP 352
K +IP + + ALEP+K+++ AVK G L +MC+++LA G K LH YT+NL ++ A+
Sbjct: 229 KARIPPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAAGIKHLHFYTMNLAQATQAVL 288
Query: 351 KE 346
+E
Sbjct: 289 EE 290
[33][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 60.1 bits (144), Expect = 1e-07
Identities = 28/62 (45%), Positives = 41/62 (66%), Gaps = 1/62 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAI 355
K ++P EI A +EPIKDN+ A++ YGI L MC+++L G + LH YTLN E + + +
Sbjct: 270 KLEVPQEITAVIEPIKDNDAAIRNYGIELAVTMCRELLVSGVVSGLHFYTLNREVATVEV 329
Query: 354 PK 349
K
Sbjct: 330 LK 331
[34][TOP]
>UniRef100_A9UZU5 Methylenetetrahydrofolate reductase n=1 Tax=Monosiga brevicollis
RepID=A9UZU5_MONBE
Length = 332
Score = 60.1 bits (144), Expect = 1e-07
Identities = 27/61 (44%), Positives = 40/61 (65%)
Frame = -2
Query: 537 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALA 358
FCK++ PA + AA+E D++EA++ + G ++C+ + A G LH YTLNLEK LA
Sbjct: 260 FCKSRTPAALRAAVEAAGDDKEAIRKVAVEHGAQLCRDLQAAGAPGLHFYTLNLEKVTLA 319
Query: 357 I 355
I
Sbjct: 320 I 320
[35][TOP]
>UniRef100_B9XQY3 Methylenetetrahydrofolate reductase n=1 Tax=bacterium Ellin514
RepID=B9XQY3_9BACT
Length = 303
Score = 59.7 bits (143), Expect = 1e-07
Identities = 26/62 (41%), Positives = 38/62 (61%)
Frame = -2
Query: 534 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 355
C K+P+ +++ LE + DN+EA AYGI TE C ++L G LH+YTLN S + +
Sbjct: 236 CGAKLPSRLVSCLEKLADNDEAAAAYGIDYATEQCAELLREGAPGLHMYTLNKAPSTIQV 295
Query: 354 PK 349
K
Sbjct: 296 LK 297
[36][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 59.7 bits (143), Expect = 1e-07
Identities = 27/62 (43%), Positives = 42/62 (67%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIP 352
KT IP + + ALEP+K+++ AVK G L +MC++++A G K LH YT+NL +S +
Sbjct: 229 KTHIPPDWLEALEPVKNDDAAVKQVGKRLIADMCRRLIASGIKHLHFYTMNLAQSTQLVL 288
Query: 351 KE 346
+E
Sbjct: 289 EE 290
[37][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 59.7 bits (143), Expect = 1e-07
Identities = 33/78 (42%), Positives = 49/78 (62%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIP 352
K KIP M ALEP+K+++ AVK G L +EMC+K+L +G LH YT+NL +S +
Sbjct: 229 KCKIPKGWMEALEPVKNDDAAVKQIGRALVSEMCRKLLDNGINHLHFYTMNLAQSTTMVL 288
Query: 351 KEPWLN*RDQHTSDTPCQ 298
+E L + +++TP Q
Sbjct: 289 EELNL----KPSTETPLQ 302
[38][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 59.7 bits (143), Expect = 1e-07
Identities = 27/62 (43%), Positives = 42/62 (67%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIP 352
K K+P+E M ALEP+K+++ AV+ G L MC++++A G K LH YT+NL ++ +
Sbjct: 229 KVKVPSEWMEALEPVKNDDSAVRDIGKTLIANMCRQLIAAGIKHLHFYTMNLAQATQLVL 288
Query: 351 KE 346
KE
Sbjct: 289 KE 290
[39][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 59.7 bits (143), Expect = 1e-07
Identities = 28/62 (45%), Positives = 41/62 (66%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIP 352
K +IP E + ALEP+K+++ AVK G L EMC+K+LA G LH YT+NL ++ ++
Sbjct: 229 KARIPPEWLEALEPVKNDDAAVKEIGKRLIAEMCRKLLAAGLNHLHFYTMNLAQATQSVL 288
Query: 351 KE 346
E
Sbjct: 289 DE 290
[40][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 59.3 bits (142), Expect = 2e-07
Identities = 28/63 (44%), Positives = 40/63 (63%), Gaps = 1/63 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAI 355
K ++P EI +EPIKDN+ A++ YGI EMCK +LA G LH YTLN E + + +
Sbjct: 273 KLEVPEEIKQVIEPIKDNDAAIRNYGIQQAVEMCKVLLASGEVSGLHFYTLNREVATMEV 332
Query: 354 PKE 346
++
Sbjct: 333 LRQ 335
[41][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 58.9 bits (141), Expect = 2e-07
Identities = 28/62 (45%), Positives = 40/62 (64%), Gaps = 1/62 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P EIM +EPIKDN+ A++ YGI L MC+++L G LH YTLN E + + +
Sbjct: 267 KLEVPQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDSGLVHGLHFYTLNREVATIDV 326
Query: 354 PK 349
K
Sbjct: 327 LK 328
[42][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 58.9 bits (141), Expect = 2e-07
Identities = 28/63 (44%), Positives = 41/63 (65%), Gaps = 1/63 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAI 355
K ++P EI + LEPIKDN+ A++ YGI L EMC+ +L G LH YTLN E + + +
Sbjct: 277 KLEVPEEITSILEPIKDNDAAIRNYGIQLAVEMCRVLLDSGKVPGLHFYTLNREVATMEV 336
Query: 354 PKE 346
++
Sbjct: 337 LRQ 339
[43][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 58.9 bits (141), Expect = 2e-07
Identities = 28/62 (45%), Positives = 40/62 (64%), Gaps = 1/62 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P EIM +EPIKDN+ A++ YGI L MC+++L G LH YTLN E + + +
Sbjct: 267 KLEVPQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDSGLVHGLHFYTLNREVATIDV 326
Query: 354 PK 349
K
Sbjct: 327 LK 328
[44][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 58.9 bits (141), Expect = 2e-07
Identities = 28/62 (45%), Positives = 40/62 (64%), Gaps = 1/62 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P EIM +EPIKDN+ A++ YGI L MC+++L G LH YTLN E + + +
Sbjct: 267 KLEVPQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDSGLVHGLHFYTLNREVATIDV 326
Query: 354 PK 349
K
Sbjct: 327 LK 328
[45][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 58.5 bits (140), Expect = 3e-07
Identities = 26/62 (41%), Positives = 42/62 (67%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIP 352
K +IP + + ALEP+K+++ AVK G L +MC+++LA G LH YT+NL ++ A+
Sbjct: 229 KARIPPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAAGINHLHFYTMNLAQATQAVL 288
Query: 351 KE 346
+E
Sbjct: 289 EE 290
[46][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 58.5 bits (140), Expect = 3e-07
Identities = 26/62 (41%), Positives = 42/62 (67%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIP 352
K +IP + + ALEP+K+++ AVK G L +MC+++LA G LH YT+NL ++ A+
Sbjct: 229 KARIPPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAAGINHLHFYTMNLAQATQAVL 288
Query: 351 KE 346
+E
Sbjct: 289 EE 290
[47][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 57.8 bits (138), Expect = 5e-07
Identities = 25/62 (40%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
Frame = -2
Query: 537 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSAL 361
+C+ +P + LEP+KD+++ V+ G L E+C+K+L G+ LH+YT+NLEK++L
Sbjct: 232 WCQINVPDNFLELLEPVKDDDQLVRDVGTELMVELCQKLLDSGYVNHLHMYTMNLEKASL 291
Query: 360 AI 355
I
Sbjct: 292 MI 293
[48][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 57.8 bits (138), Expect = 5e-07
Identities = 28/62 (45%), Positives = 41/62 (66%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIP 352
K +IP + + ALEP+K+++ AV+ G L +MCKKILA G LH YT+NL+++ I
Sbjct: 229 KIRIPPDWLEALEPVKNDDAAVRNLGKSLVADMCKKILASGIYHLHFYTMNLQQATKMIL 288
Query: 351 KE 346
E
Sbjct: 289 DE 290
[49][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 57.8 bits (138), Expect = 5e-07
Identities = 28/62 (45%), Positives = 41/62 (66%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIP 352
K +IP + + ALEP+K+++ AV+ G L +MCKKILA G LH YT+NL+++ I
Sbjct: 229 KIRIPPDWLEALEPVKNDDAAVRNLGKSLVADMCKKILASGIYHLHFYTMNLQQATKMIL 288
Query: 351 KE 346
E
Sbjct: 289 DE 290
[50][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 57.8 bits (138), Expect = 5e-07
Identities = 28/62 (45%), Positives = 40/62 (64%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIP 352
K ++P M ALEP K+++ AVK G L +EMC+KIL G + LH YT+NL +S +
Sbjct: 229 KCRVPPSWMEALEPCKNDDAAVKQIGKKLVSEMCRKILDSGIRHLHFYTMNLAQSTKMVL 288
Query: 351 KE 346
+E
Sbjct: 289 EE 290
[51][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 57.8 bits (138), Expect = 5e-07
Identities = 29/63 (46%), Positives = 38/63 (60%), Gaps = 1/63 (1%)
Frame = -2
Query: 534 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH-GFKTLHLYTLNLEKSALA 358
C P +++ LEPIK ++ VK +GIHL +M K I G + HLYTLNLEKSA
Sbjct: 255 CGVHTPEDVLEQLEPIKMDDAKVKEHGIHLSIDMIKSIREQTGIRAFHLYTLNLEKSATC 314
Query: 357 IPK 349
+ K
Sbjct: 315 VIK 317
[52][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 57.4 bits (137), Expect = 7e-07
Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P EI +EPIKDN+ A++ YGI L +C+++LA G LH YTLN E + +
Sbjct: 296 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEV 355
Query: 354 PK 349
K
Sbjct: 356 LK 357
[53][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 57.4 bits (137), Expect = 7e-07
Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P EI +EPIKDN+ A++ YGI L +C+++LA G LH YTLN E + +
Sbjct: 314 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEV 373
Query: 354 PK 349
K
Sbjct: 374 LK 375
[54][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 57.4 bits (137), Expect = 7e-07
Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P EI +EPIKDN+ A++ YGI L +C+++LA G LH YTLN E + +
Sbjct: 273 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEV 332
Query: 354 PK 349
K
Sbjct: 333 LK 334
[55][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 57.4 bits (137), Expect = 7e-07
Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P EI +EPIKDN+ A++ YGI L +C+++LA G LH YTLN E + +
Sbjct: 303 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEV 362
Query: 354 PK 349
K
Sbjct: 363 LK 364
[56][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 57.4 bits (137), Expect = 7e-07
Identities = 27/62 (43%), Positives = 41/62 (66%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIP 352
K +IP E + ALEP+K+++ AVK G L +MC+++LA G LH YT+NL +S +
Sbjct: 229 KIRIPPEWLEALEPVKNDDAAVKEIGKGLIADMCRRLLAAGINHLHFYTMNLAQSTQLVL 288
Query: 351 KE 346
+E
Sbjct: 289 EE 290
[57][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 57.0 bits (136), Expect = 8e-07
Identities = 29/64 (45%), Positives = 42/64 (65%), Gaps = 1/64 (1%)
Frame = -2
Query: 525 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIPKE 346
KIP E MA LEP+K+++ AV+ G L EMC+KI+ G + LH YT+NL ++ + +E
Sbjct: 231 KIPEEWMAKLEPVKNDDVAVREIGKTLVAEMCRKIVDAGIRHLHFYTMNLAQATRMVLEE 290
Query: 345 -PWL 337
WL
Sbjct: 291 LDWL 294
[58][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 57.0 bits (136), Expect = 8e-07
Identities = 28/58 (48%), Positives = 40/58 (68%), Gaps = 1/58 (1%)
Frame = -2
Query: 525 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
KIP + LEP+KD+++ V+ G L +MC+KIL G+ K LH+YT+NLEK+ L I
Sbjct: 236 KIPQAFLDVLEPVKDDDQLVRDKGSELIVDMCQKILNSGYVKHLHIYTMNLEKAPLII 293
[59][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 57.0 bits (136), Expect = 8e-07
Identities = 27/62 (43%), Positives = 41/62 (66%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIP 352
K KIP + ALEP+K+++ AV+ G L EMC+K+LA+G LH YT+NL ++ +
Sbjct: 229 KAKIPQAWLDALEPVKNDDVAVRDIGKSLVAEMCRKLLANGIHHLHFYTMNLAQATRMVL 288
Query: 351 KE 346
+E
Sbjct: 289 EE 290
[60][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 56.6 bits (135), Expect = 1e-06
Identities = 27/62 (43%), Positives = 38/62 (61%), Gaps = 1/62 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P EI +EPIKDN+ A++ YGI L +C ++LA G LH YTLN E + +
Sbjct: 296 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLHFYTLNREMATTEV 355
Query: 354 PK 349
K
Sbjct: 356 LK 357
[61][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 56.6 bits (135), Expect = 1e-06
Identities = 27/62 (43%), Positives = 38/62 (61%), Gaps = 1/62 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P EI +EPIKDN+ A++ YGI L +C ++LA G LH YTLN E + +
Sbjct: 314 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLHFYTLNREMATTEV 373
Query: 354 PK 349
K
Sbjct: 374 LK 375
[62][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 56.6 bits (135), Expect = 1e-06
Identities = 26/63 (41%), Positives = 41/63 (65%), Gaps = 1/63 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAI 355
K ++P EI + +EPIKDN+ A++ YGI L +MC+ +L G LH YTLN E + + +
Sbjct: 277 KLELPEEITSIIEPIKDNDAAIRNYGIQLAVQMCRVLLDSGKVPGLHFYTLNREVATMEV 336
Query: 354 PKE 346
++
Sbjct: 337 LRQ 339
[63][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 56.6 bits (135), Expect = 1e-06
Identities = 26/63 (41%), Positives = 41/63 (65%), Gaps = 1/63 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAI 355
K ++P EI + +EPIKDN+ A++ YGI L +MC+ +L G LH YTLN E + + +
Sbjct: 277 KLELPEEITSIIEPIKDNDAAIRNYGIQLAVQMCRVLLDSGKVPGLHFYTLNREVATMEV 336
Query: 354 PKE 346
++
Sbjct: 337 LRQ 339
[64][TOP]
>UniRef100_Q0EWI5 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0EWI5_9PROT
Length = 251
Score = 56.6 bits (135), Expect = 1e-06
Identities = 26/60 (43%), Positives = 38/60 (63%)
Frame = -2
Query: 534 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 355
C IPA + ++PI+D+ EAVKA GI L + C+++L G LH YTLN ++ +AI
Sbjct: 184 CGASIPAWLHEQMQPIRDDLEAVKALGIELAAKQCRELLQAGVPGLHFYTLNKSEATIAI 243
[65][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 56.6 bits (135), Expect = 1e-06
Identities = 27/63 (42%), Positives = 40/63 (63%), Gaps = 1/63 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K +IP EI A+EPI+DN+EA++ YG+H M +++ G LH YTLN E + + I
Sbjct: 262 KLEIPDEIREAIEPIRDNDEAIRNYGVHQAVTMIRELFDSGLVNGLHFYTLNREVATIQI 321
Query: 354 PKE 346
K+
Sbjct: 322 LKQ 324
[66][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 56.6 bits (135), Expect = 1e-06
Identities = 27/62 (43%), Positives = 39/62 (62%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIP 352
K K+P M ALEP+K+++ AVK G L MC+KIL G + LH YT+NL ++ +
Sbjct: 229 KCKVPESWMEALEPVKNDDAAVKQIGKKLVANMCQKILDSGIRHLHFYTMNLAQATKMVL 288
Query: 351 KE 346
+E
Sbjct: 289 EE 290
[67][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 56.6 bits (135), Expect = 1e-06
Identities = 27/62 (43%), Positives = 39/62 (62%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIP 352
K K+P M ALEP+K+++ AVK G L MC+KIL G + LH YT+NL ++ +
Sbjct: 229 KCKVPESWMEALEPVKNDDAAVKQIGKKLVANMCQKILDSGIRHLHFYTMNLAQATKMVL 288
Query: 351 KE 346
+E
Sbjct: 289 EE 290
[68][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 56.6 bits (135), Expect = 1e-06
Identities = 30/66 (45%), Positives = 41/66 (62%), Gaps = 1/66 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKS-ALAI 355
+ +IP E + LEPIK ++ AV+ G L E+C+KILA G LH YT+NL +S AL +
Sbjct: 224 QARIPEEWLQRLEPIKTDDAAVRIVGRQLVVELCRKILAAGIHHLHFYTMNLAQSTALIL 283
Query: 354 PKEPWL 337
WL
Sbjct: 284 EDLDWL 289
[69][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 56.6 bits (135), Expect = 1e-06
Identities = 27/62 (43%), Positives = 38/62 (61%), Gaps = 1/62 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P EI +EPIKDN+ A++ YGI L +C ++LA G LH YTLN E + +
Sbjct: 273 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLHFYTLNREMATTEV 332
Query: 354 PK 349
K
Sbjct: 333 LK 334
[70][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S5W8_NEMVE
Length = 619
Score = 56.2 bits (134), Expect = 1e-06
Identities = 31/71 (43%), Positives = 46/71 (64%), Gaps = 7/71 (9%)
Frame = -2
Query: 525 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSA----- 364
K+P EI+ L+ K++ EA++A+GI T+MC+++ A G + +HLYTLN+EK
Sbjct: 251 KVPNEILEVLKSGKEDLEAIQAFGIQHATKMCQELFASGKVQGIHLYTLNIEKPVMSILE 310
Query: 363 -LAIPKEPWLN 334
L I KEP LN
Sbjct: 311 NLKISKEPELN 321
[71][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 56.2 bits (134), Expect = 1e-06
Identities = 25/62 (40%), Positives = 41/62 (66%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIP 352
KT+IP + + ALEP+K+++ AV+ G L +MC++++A G LH YT+NL +S +
Sbjct: 229 KTRIPPDWLEALEPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVL 288
Query: 351 KE 346
E
Sbjct: 289 DE 290
[72][TOP]
>UniRef100_UPI000194E904 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH), partial n=1 Tax=Taeniopygia guttata
RepID=UPI000194E904
Length = 345
Score = 55.8 bits (133), Expect = 2e-06
Identities = 26/62 (41%), Positives = 38/62 (61%), Gaps = 1/62 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P EI +EPIKDN+ A++ YG+ L MC+++L G LH YTLN E + +
Sbjct: 275 KLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEV 334
Query: 354 PK 349
K
Sbjct: 335 LK 336
[73][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 55.8 bits (133), Expect = 2e-06
Identities = 26/62 (41%), Positives = 38/62 (61%), Gaps = 1/62 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P EI +EPIKDN+ A++ YG+ L MC+++L G LH YTLN E + +
Sbjct: 275 KLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEV 334
Query: 354 PK 349
K
Sbjct: 335 LK 336
[74][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
RepID=UPI0000E814FF
Length = 508
Score = 55.8 bits (133), Expect = 2e-06
Identities = 26/62 (41%), Positives = 38/62 (61%), Gaps = 1/62 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P EI +EPIKDN+ A++ YG+ L MC+++L G LH YTLN E + +
Sbjct: 131 KLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGLVHGLHFYTLNREVATTEV 190
Query: 354 PK 349
K
Sbjct: 191 LK 192
[75][TOP]
>UniRef100_UPI0000ECA34F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Gallus
gallus RepID=UPI0000ECA34F
Length = 640
Score = 55.8 bits (133), Expect = 2e-06
Identities = 26/62 (41%), Positives = 38/62 (61%), Gaps = 1/62 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P EI +EPIKDN+ A++ YG+ L MC+++L G LH YTLN E + +
Sbjct: 263 KLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGLVHGLHFYTLNREVATTEV 322
Query: 354 PK 349
K
Sbjct: 323 LK 324
[76][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 55.8 bits (133), Expect = 2e-06
Identities = 25/62 (40%), Positives = 41/62 (66%), Gaps = 1/62 (1%)
Frame = -2
Query: 537 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSAL 361
+C+ +IP + + LEP+KD++ V+ G L +MC+K+L G K LH YT+NLEK+ +
Sbjct: 228 WCQIQIPQDFLDQLEPVKDDDMRVRELGTQLVADMCQKMLDSGKIKHLHFYTMNLEKATV 287
Query: 360 AI 355
+
Sbjct: 288 MV 289
[77][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 55.5 bits (132), Expect = 2e-06
Identities = 25/63 (39%), Positives = 40/63 (63%), Gaps = 1/63 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P +I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +
Sbjct: 313 KLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEV 372
Query: 354 PKE 346
K+
Sbjct: 373 LKQ 375
[78][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 55.5 bits (132), Expect = 2e-06
Identities = 25/63 (39%), Positives = 40/63 (63%), Gaps = 1/63 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P +I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +
Sbjct: 313 KLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEV 372
Query: 354 PKE 346
K+
Sbjct: 373 LKQ 375
[79][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 55.5 bits (132), Expect = 2e-06
Identities = 25/63 (39%), Positives = 40/63 (63%), Gaps = 1/63 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P +I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +
Sbjct: 313 KLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEV 372
Query: 354 PKE 346
K+
Sbjct: 373 LKQ 375
[80][TOP]
>UniRef100_B4D0K5 Methylenetetrahydrofolate reductase n=1 Tax=Chthoniobacter flavus
Ellin428 RepID=B4D0K5_9BACT
Length = 297
Score = 55.5 bits (132), Expect = 2e-06
Identities = 25/60 (41%), Positives = 35/60 (58%)
Frame = -2
Query: 534 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 355
C K+PA+ + L+ + ++EAV AYGI TE C +L G LH YTLN +S + I
Sbjct: 229 CGAKLPAQFLRRLDELDGDDEAVAAYGIEYATEQCASLLEFGVPGLHFYTLNKARSTVQI 288
[81][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 55.5 bits (132), Expect = 2e-06
Identities = 27/57 (47%), Positives = 40/57 (70%), Gaps = 1/57 (1%)
Frame = -2
Query: 522 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAI 355
IP + L+PIKD++E V+ G +L EMC+K+L G+ + LH+YT+NLEK+ L I
Sbjct: 237 IPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMI 293
[82][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 55.5 bits (132), Expect = 2e-06
Identities = 25/57 (43%), Positives = 37/57 (64%)
Frame = -2
Query: 525 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 355
+IP + ALEP+KD++ V+ G L EMC+K++ +G LH YT+NLEK+ I
Sbjct: 232 RIPQHFIDALEPLKDDDALVREKGSELMAEMCQKLVDNGITRLHFYTMNLEKATKMI 288
[83][TOP]
>UniRef100_B5VIK4 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VIK4_YEAS6
Length = 411
Score = 55.5 bits (132), Expect = 2e-06
Identities = 27/57 (47%), Positives = 40/57 (70%), Gaps = 1/57 (1%)
Frame = -2
Query: 522 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAI 355
IP + L+PIKD++E V+ G +L EMC+K+L G+ + LH+YT+NLEK+ L I
Sbjct: 48 IPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMI 104
[84][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 55.5 bits (132), Expect = 2e-06
Identities = 27/57 (47%), Positives = 40/57 (70%), Gaps = 1/57 (1%)
Frame = -2
Query: 522 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAI 355
IP + L+PIKD++E V+ G +L EMC+K+L G+ + LH+YT+NLEK+ L I
Sbjct: 237 IPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMI 293
[85][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 55.5 bits (132), Expect = 2e-06
Identities = 25/63 (39%), Positives = 40/63 (63%), Gaps = 1/63 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P +I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +
Sbjct: 272 KLEVPQKIKDVIEPIKDNDAAIRNYGIELAVRLCRELLDSGLVPGLHFYTLNREVATMEV 331
Query: 354 PKE 346
K+
Sbjct: 332 LKQ 334
[86][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 55.5 bits (132), Expect = 2e-06
Identities = 27/57 (47%), Positives = 40/57 (70%), Gaps = 1/57 (1%)
Frame = -2
Query: 522 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAI 355
IP + L+PIKD++E V+ G +L EMC+K+L G+ + LH+YT+NLEK+ L I
Sbjct: 237 IPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMI 293
[87][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 55.1 bits (131), Expect = 3e-06
Identities = 26/62 (41%), Positives = 41/62 (66%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIP 352
+ KIP E + ALEP+K+++ AV+ G L MC+K+LA+G LH YT+NL ++ +
Sbjct: 229 QAKIPQEWLDALEPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLL 288
Query: 351 KE 346
+E
Sbjct: 289 EE 290
[88][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 54.7 bits (130), Expect = 4e-06
Identities = 25/63 (39%), Positives = 39/63 (61%), Gaps = 1/63 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +
Sbjct: 278 KLEVPQTIKDVIEPIKDNDAAIRNYGIELAVNLCRELLDSGLVPGLHFYTLNREVATMEV 337
Query: 354 PKE 346
K+
Sbjct: 338 LKQ 340
[89][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 54.7 bits (130), Expect = 4e-06
Identities = 25/63 (39%), Positives = 39/63 (61%), Gaps = 1/63 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +
Sbjct: 313 KLEVPQTIKDVIEPIKDNDAAIRNYGIELAVNLCRELLDSGLVPGLHFYTLNREVATMEV 372
Query: 354 PKE 346
K+
Sbjct: 373 LKQ 375
[90][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 54.7 bits (130), Expect = 4e-06
Identities = 25/62 (40%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P +I +EPIKDN+ A++ YGI +C+++LA G LH YTLN E + + +
Sbjct: 272 KLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNREVATIEV 331
Query: 354 PK 349
K
Sbjct: 332 LK 333
[91][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 54.7 bits (130), Expect = 4e-06
Identities = 34/104 (32%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILA-HGFKTLHLYTLNLEKSALAI 355
K +P I+ +E IKDN+EA++ +GI T +CKK+LA +H+YTLN E++ + +
Sbjct: 256 KLPVPQRILDTIESIKDNDEAIRKFGIVEATNLCKKLLASDDVPGIHVYTLNREEAVVKL 315
Query: 354 PKEPWLN*RDQHTSDTPCQCYSGLKKMVRIKRGQRKTWWFKWPK 223
K L + P + + K RI R +W PK
Sbjct: 316 LKRVGLWHEESIYKSLPWRPSANGK---RISEDVRPIFWASRPK 356
[92][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6H337_AJECH
Length = 524
Score = 54.7 bits (130), Expect = 4e-06
Identities = 25/55 (45%), Positives = 38/55 (69%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKS 367
K +IP + + ALEP+K+++ AV+ G L MC+KILA G LH YT+NL+++
Sbjct: 120 KIRIPPDWLEALEPVKNDDAAVRNLGKSLVANMCRKILAAGIYHLHFYTMNLQQA 174
[93][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 54.7 bits (130), Expect = 4e-06
Identities = 25/55 (45%), Positives = 38/55 (69%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKS 367
K +IP + + ALEP+K+++ AV+ G L MC+KILA G LH YT+NL+++
Sbjct: 229 KIRIPPDWLEALEPVKNDDAAVRNLGKSLVANMCRKILAAGIYHLHFYTMNLQQA 283
[94][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 54.7 bits (130), Expect = 4e-06
Identities = 27/60 (45%), Positives = 39/60 (65%)
Frame = -2
Query: 525 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIPKE 346
KIP E M LEP+K+++ AV+ G L E+C+KILA G LH YT+NL ++ + +E
Sbjct: 231 KIPDEWMQRLEPVKNDDVAVRDIGKTLVAELCRKILAAGIHHLHFYTMNLAQATRMVLEE 290
[95][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 54.7 bits (130), Expect = 4e-06
Identities = 28/63 (44%), Positives = 39/63 (61%), Gaps = 2/63 (3%)
Frame = -2
Query: 528 TKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKIL--AHGFKTLHLYTLNLEKSALAI 355
TKIP + ALEP+K ++E V+ G L +MC+KIL G + LH YT+NLEK +
Sbjct: 191 TKIPQFFLDALEPVKSDDEKVREVGTKLVADMCRKILDSGLGIRGLHFYTMNLEKGTRML 250
Query: 354 PKE 346
+E
Sbjct: 251 LEE 253
[96][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 54.7 bits (130), Expect = 4e-06
Identities = 25/62 (40%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P +I +EPIKDN+ A++ YGI +C+++LA G LH YTLN E + + +
Sbjct: 272 KLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNREVATIEV 331
Query: 354 PK 349
K
Sbjct: 332 LK 333
[97][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 54.3 bits (129), Expect = 6e-06
Identities = 27/64 (42%), Positives = 42/64 (65%), Gaps = 1/64 (1%)
Frame = -2
Query: 525 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIPKE 346
K+P E MA LE +K+++ AV+ G L +MC+KIL+ G + LH YT+NL ++ + +E
Sbjct: 231 KVPEEWMAKLESVKNDDVAVRDIGKTLVADMCRKILSAGIRHLHFYTMNLAQATRMVLEE 290
Query: 345 -PWL 337
WL
Sbjct: 291 LDWL 294
[98][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 54.3 bits (129), Expect = 6e-06
Identities = 26/58 (44%), Positives = 39/58 (67%), Gaps = 1/58 (1%)
Frame = -2
Query: 525 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
KIP + ALEPIKD++ V+ G L +EMC++++ G+ LH YT+NLEK+ + I
Sbjct: 232 KIPPHFLEALEPIKDDDFLVREKGTELVSEMCQQLIESGYVNHLHFYTMNLEKATVMI 289
[99][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 53.9 bits (128), Expect = 7e-06
Identities = 26/62 (41%), Positives = 38/62 (61%), Gaps = 1/62 (1%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
K ++P EI +EPIKDN+ A++ YGI +C+++LA G LH YTLN E + +
Sbjct: 272 KLEVPQEIKDVIEPIKDNDGAIRNYGIDQAVSLCQQLLASGLVPGLHFYTLNREVATTEV 331
Query: 354 PK 349
K
Sbjct: 332 LK 333
[100][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 53.9 bits (128), Expect = 7e-06
Identities = 27/67 (40%), Positives = 38/67 (56%), Gaps = 6/67 (8%)
Frame = -2
Query: 537 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFK------TLHLYTLNL 376
FCKTK+P I LE +K +++ VK G+ + MC +I+++G LH YTLNL
Sbjct: 201 FCKTKVPRAIADQLEQVKGDDQRVKDLGVEICVAMCSQIMSYGVDHTHSSGGLHFYTLNL 260
Query: 375 EKSALAI 355
E S I
Sbjct: 261 ESSVCRI 267
[101][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 53.9 bits (128), Expect = 7e-06
Identities = 27/67 (40%), Positives = 38/67 (56%), Gaps = 6/67 (8%)
Frame = -2
Query: 537 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFK------TLHLYTLNL 376
FCKTK+P I LE +K +++ VK G+ + MC +I+++G LH YTLNL
Sbjct: 201 FCKTKVPRAIADQLEQVKGDDQRVKDLGVEICVAMCSQIMSYGVDHTHSSGGLHFYTLNL 260
Query: 375 EKSALAI 355
E S I
Sbjct: 261 ESSVCRI 267
[102][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 53.9 bits (128), Expect = 7e-06
Identities = 26/62 (41%), Positives = 39/62 (62%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIP 352
K +IP + ALEP+K+++ AV+ G L MCKK+LA G LH YT+NL+++ +
Sbjct: 229 KIQIPPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLASGIHHLHFYTMNLQQATKMVL 288
Query: 351 KE 346
E
Sbjct: 289 DE 290
[103][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 53.9 bits (128), Expect = 7e-06
Identities = 26/62 (41%), Positives = 39/62 (62%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIP 352
K +IP + ALEP+K+++ AV+ G L MCKK+LA G LH YT+NL+++ +
Sbjct: 229 KIQIPPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLASGIHHLHFYTMNLQQATKMVL 288
Query: 351 KE 346
E
Sbjct: 289 DE 290
[104][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 53.9 bits (128), Expect = 7e-06
Identities = 26/62 (41%), Positives = 39/62 (62%)
Frame = -2
Query: 531 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIP 352
K +IP + ALEP+K+++ AV+ G L MCKK+LA G LH YT+NL+++ +
Sbjct: 229 KIQIPPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLASGIHHLHFYTMNLQQATKMVL 288
Query: 351 KE 346
E
Sbjct: 289 DE 290
[105][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 53.5 bits (127), Expect = 9e-06
Identities = 26/57 (45%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
Frame = -2
Query: 522 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 355
IP + AL+PIKD++ V+ G L +EMC+K+L G+ LH YT+NLEK+ + I
Sbjct: 232 IPQHFLDALDPIKDDDYLVREKGTELVSEMCQKLLESGYINHLHFYTMNLEKATVMI 288