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[1][TOP]
>UniRef100_B9GZM5 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9GZM5_POPTR
          Length = 540

 Score =  214 bits (545), Expect = 2e-54
 Identities = 101/121 (83%), Positives = 114/121 (94%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           K IQKGI+EI ELF++GRPDMTIVAFGS+ LDIFEVNDIMSSKGWHLNALQRPNSIHIC+
Sbjct: 420 KRIQKGIKEIPELFIIGRPDMTIVAFGSNDLDIFEVNDIMSSKGWHLNALQRPNSIHICI 479

Query: 182 TLQLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMDGT 361
           TLQ  P V+DFL+DLKESV+TVK+NPGPI+GGLAPIYGAAGK+PDRGMVQELLV++MD T
Sbjct: 480 TLQHAPVVEDFLRDLKESVQTVKENPGPINGGLAPIYGAAGKIPDRGMVQELLVNYMDST 539

Query: 362 C 364
           C
Sbjct: 540 C 540

[2][TOP]
>UniRef100_A7R367 Chromosome undetermined scaffold_488, whole genome shotgun sequence
           n=1 Tax=Vitis vinifera RepID=A7R367_VITVI
          Length = 537

 Score =  209 bits (533), Expect = 6e-53
 Identities = 99/121 (81%), Positives = 114/121 (94%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           K +Q+GI++I ELFV+GRPDMTIVAFGS+V+DIFEVNDI+SSKGWHLNALQRPNSIHIC+
Sbjct: 417 KKLQRGIKDIPELFVIGRPDMTIVAFGSNVVDIFEVNDILSSKGWHLNALQRPNSIHICL 476

Query: 182 TLQLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMDGT 361
           TLQ V  ++DFLKDLKESV+TVK+NPGPI+GGLAPIYGAAGKMPDRGMV ELLV+FMD T
Sbjct: 477 TLQHVTILEDFLKDLKESVQTVKQNPGPINGGLAPIYGAAGKMPDRGMVGELLVNFMDST 536

Query: 362 C 364
           C
Sbjct: 537 C 537

[3][TOP]
>UniRef100_B9RMB8 Sphingosine phosphate lyase, putative n=1 Tax=Ricinus communis
           RepID=B9RMB8_RICCO
          Length = 541

 Score =  207 bits (528), Expect = 2e-52
 Identities = 98/121 (80%), Positives = 112/121 (92%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           K IQKGIEE+ ELFV+GRPDMTIVAFGS+VLDIFEVNDI+SSKGWHLNALQRPNS+HICV
Sbjct: 421 KKIQKGIEEMPELFVIGRPDMTIVAFGSNVLDIFEVNDILSSKGWHLNALQRPNSLHICV 480

Query: 182 TLQLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMDGT 361
           TLQ     +DFL+DL+ESV+TVK+NPGPI+GGLAPIYGAAGK+PDR MVQELLV++MD T
Sbjct: 481 TLQHASVYEDFLQDLRESVQTVKQNPGPINGGLAPIYGAAGKIPDRSMVQELLVNYMDST 540

Query: 362 C 364
           C
Sbjct: 541 C 541

[4][TOP]
>UniRef100_Q9C509 Sphingosine-1-phosphate lyase n=2 Tax=Arabidopsis thaliana
           RepID=SGPL_ARATH
          Length = 544

 Score =  205 bits (522), Expect = 1e-51
 Identities = 97/118 (82%), Positives = 108/118 (91%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           K +++G+ EI ELFV+G+PDMTIVAFGS  LDIFEVNDIMSSKGWHLNALQRPNSIHIC+
Sbjct: 424 KRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHLNALQRPNSIHICI 483

Query: 182 TLQLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           TLQ VP VDDFL+DL+E+VETVK NPGPI+GGLAPIYGAAGKMPDRGMV ELLV FMD
Sbjct: 484 TLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPDRGMVNELLVSFMD 541

[5][TOP]
>UniRef100_A5BC55 Putative uncharacterized protein n=1 Tax=Vitis vinifera
           RepID=A5BC55_VITVI
          Length = 133

 Score =  204 bits (519), Expect = 2e-51
 Identities = 97/118 (82%), Positives = 112/118 (94%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           K +Q+GI++I ELFV+GRPDMTIVAFGS+V+DIFEVNDI+SSKGWHLNALQRPNSIHIC+
Sbjct: 5   KKLQRGIKDIPELFVIGRPDMTIVAFGSNVVDIFEVNDILSSKGWHLNALQRPNSIHICL 64

Query: 182 TLQLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           TLQ V  ++DFLKDLKESV+TVK+NPGPI+GGLAPIYGAAGKMPDRGMV ELLV+FMD
Sbjct: 65  TLQHVTILEDFLKDLKESVQTVKQNPGPINGGLAPIYGAAGKMPDRGMVGELLVNFMD 122

[6][TOP]
>UniRef100_UPI0000DD88F6 Os01g0100900 n=1 Tax=Oryza sativa Japonica Group
           RepID=UPI0000DD88F6
          Length = 537

 Score =  201 bits (512), Expect = 2e-50
 Identities = 95/121 (78%), Positives = 109/121 (90%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           K IQ+GIE+I  LFV+G+PDMT+VAFGSD +DIFEVNDIMSSKGWHLNALQRPNS+HICV
Sbjct: 417 KKIQRGIEDIPGLFVIGKPDMTVVAFGSDSVDIFEVNDIMSSKGWHLNALQRPNSLHICV 476

Query: 182 TLQLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMDGT 361
           TLQ     ++FLKDLK+SV+TVK NPGPISGG APIYGAAGKMPDRGMV+ELLV+FMD +
Sbjct: 477 TLQHTVIYEEFLKDLKDSVDTVKANPGPISGGRAPIYGAAGKMPDRGMVRELLVEFMDAS 536

Query: 362 C 364
           C
Sbjct: 537 C 537

[7][TOP]
>UniRef100_C5XFN1 Putative uncharacterized protein Sb03g009170 n=1 Tax=Sorghum
           bicolor RepID=C5XFN1_SORBI
          Length = 533

 Score =  201 bits (512), Expect = 2e-50
 Identities = 96/121 (79%), Positives = 108/121 (89%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           K IQ+GI EI  LFV+G+PDMTIVAFGSDV+DIFEVNDIMSSKGWHLNALQRPNS+HICV
Sbjct: 413 KKIQRGIGEIPGLFVIGKPDMTIVAFGSDVVDIFEVNDIMSSKGWHLNALQRPNSLHICV 472

Query: 182 TLQLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMDGT 361
           TLQ     D FLKDL++SV+TVK NPGPISGG+APIYGAAGKMPDRG V+ELLV+FMD +
Sbjct: 473 TLQHTTIYDQFLKDLQDSVDTVKANPGPISGGMAPIYGAAGKMPDRGTVRELLVEFMDSS 532

Query: 362 C 364
           C
Sbjct: 533 C 533

[8][TOP]
>UniRef100_B7FAK6 Os01g0100900 protein n=2 Tax=Oryza sativa RepID=B7FAK6_ORYSJ
          Length = 539

 Score =  201 bits (512), Expect = 2e-50
 Identities = 95/121 (78%), Positives = 109/121 (90%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           K IQ+GIE+I  LFV+G+PDMT+VAFGSD +DIFEVNDIMSSKGWHLNALQRPNS+HICV
Sbjct: 419 KKIQRGIEDIPGLFVIGKPDMTVVAFGSDSVDIFEVNDIMSSKGWHLNALQRPNSLHICV 478

Query: 182 TLQLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMDGT 361
           TLQ     ++FLKDLK+SV+TVK NPGPISGG APIYGAAGKMPDRGMV+ELLV+FMD +
Sbjct: 479 TLQHTVIYEEFLKDLKDSVDTVKANPGPISGGRAPIYGAAGKMPDRGMVRELLVEFMDAS 538

Query: 362 C 364
           C
Sbjct: 539 C 539

[9][TOP]
>UniRef100_Q52RG7 Sphingosine-1-phosphate lyase n=1 Tax=Oryza sativa Japonica Group
           RepID=SGPL_ORYSJ
          Length = 539

 Score =  201 bits (512), Expect = 2e-50
 Identities = 95/121 (78%), Positives = 109/121 (90%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           K IQ+GIE+I  LFV+G+PDMT+VAFGSD +DIFEVNDIMSSKGWHLNALQRPNS+HICV
Sbjct: 419 KKIQRGIEDIPGLFVIGKPDMTVVAFGSDSVDIFEVNDIMSSKGWHLNALQRPNSLHICV 478

Query: 182 TLQLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMDGT 361
           TLQ     ++FLKDLK+SV+TVK NPGPISGG APIYGAAGKMPDRGMV+ELLV+FMD +
Sbjct: 479 TLQHTVIYEEFLKDLKDSVDTVKANPGPISGGRAPIYGAAGKMPDRGMVRELLVEFMDAS 538

Query: 362 C 364
           C
Sbjct: 539 C 539

[10][TOP]
>UniRef100_B6SZI2 Sphingosine-1-phosphate lyase n=1 Tax=Zea mays RepID=B6SZI2_MAIZE
          Length = 533

 Score =  199 bits (506), Expect = 8e-50
 Identities = 95/121 (78%), Positives = 106/121 (87%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           K IQ+GI EI  LFV+G+PDMT+VAFGSDV+DIFEVNDIMSSKGWHLNALQRPNS+HICV
Sbjct: 413 KKIQRGIGEIPGLFVIGKPDMTVVAFGSDVVDIFEVNDIMSSKGWHLNALQRPNSLHICV 472

Query: 182 TLQLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMDGT 361
           TLQ     D FLKDL++SV TVK NPGPISGG APIYGAAGKMPDRG V+ELLV+FMD +
Sbjct: 473 TLQHTTVYDQFLKDLQDSVNTVKANPGPISGGKAPIYGAAGKMPDRGTVRELLVEFMDSS 532

Query: 362 C 364
           C
Sbjct: 533 C 533

[11][TOP]
>UniRef100_A9NUF1 Putative uncharacterized protein n=1 Tax=Picea sitchensis
           RepID=A9NUF1_PICSI
          Length = 544

 Score =  185 bits (469), Expect = 2e-45
 Identities = 83/121 (68%), Positives = 106/121 (87%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           K+IQ+GI++I ELF+VGRPDMT++AFGSD LDIF+VND++S++GWHLNALQRPNSIHIC+
Sbjct: 424 KTIQQGIKQIPELFIVGRPDMTVIAFGSDKLDIFKVNDVLSTQGWHLNALQRPNSIHICL 483

Query: 182 TLQLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMDGT 361
           TLQ     +DFLKDLK++V TV++NP     G+APIYGAA KMPDRGMVQ+LL+++MD T
Sbjct: 484 TLQHTLIAEDFLKDLKKAVTTVQENPSAFEDGMAPIYGAAAKMPDRGMVQDLLIEYMDNT 543

Query: 362 C 364
           C
Sbjct: 544 C 544

[12][TOP]
>UniRef100_B9GMN2 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9GMN2_POPTR
          Length = 107

 Score =  158 bits (399), Expect = 2e-37
 Identities = 83/121 (68%), Positives = 93/121 (76%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           K IQKG            PDMTIVA  S+ LDIFEVNDIM+SKGWHLNALQRPNSIHICV
Sbjct: 5   KRIQKG------------PDMTIVAIRSNDLDIFEVNDIMASKGWHLNALQRPNSIHICV 52

Query: 182 TLQLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMDGT 361
           TLQ  P  +DFL+DL+ESV TV      ISGGLAPIYGAAGK+PDRGM++ELLV++MD T
Sbjct: 53  TLQHAPVFEDFLRDLRESVRTV------ISGGLAPIYGAAGKIPDRGMLEELLVNYMDST 106

Query: 362 C 364
           C
Sbjct: 107 C 107

[13][TOP]
>UniRef100_A9SKK9 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
           RepID=A9SKK9_PHYPA
          Length = 537

 Score =  149 bits (375), Expect = 1e-34
 Identities = 67/121 (55%), Positives = 93/121 (76%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           ++I+ GI +I  L+V+G+PDMT+VAF S  L+I++VN+ M+ KGW LNAL +P+S+HICV
Sbjct: 417 RNIKLGIPDIEGLYVLGKPDMTVVAFASKELNIYKVNEAMAEKGWSLNALHKPSSVHICV 476

Query: 182 TLQLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMDGT 361
           TLQ V  VD FL DLK +V+ V+ NPG    G+APIYGA   +PDRG ++++LVD+MD T
Sbjct: 477 TLQHVDVVDKFLDDLKAAVKYVRDNPGKYEDGMAPIYGAGATLPDRGTIRDILVDYMDST 536

Query: 362 C 364
           C
Sbjct: 537 C 537

[14][TOP]
>UniRef100_Q54RV9 Sphingosine-1-phosphate lyase n=1 Tax=Dictyostelium discoideum
           RepID=SGPL_DICDI
          Length = 528

 Score =  119 bits (297), Expect = 1e-25
 Identities = 60/119 (50%), Positives = 82/119 (68%), Gaps = 1/119 (0%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           K I KG++ I  + ++G P   +VAF  D  +IF VND MS KGWHLNALQRPNS+H+CV
Sbjct: 399 KKIIKGLQSINGVKIIGDPKAMVVAFTCD--NIFYVNDYMSKKGWHLNALQRPNSLHVCV 456

Query: 182 TLQLVPAVDDFLKDLKESVETVKKNPGPI-SGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           T +++     F++DLK+S++ VK N G +   G APIYG+A  +PDR MV  +L DF+D
Sbjct: 457 TAKMIGMESLFIEDLKDSIKLVKDNSGSLPKDGTAPIYGSAHSVPDREMVGTILSDFID 515

[15][TOP]
>UniRef100_UPI00006A2233 Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (hSPL)
           (Sphingosine-1-phosphate aldolase). n=1 Tax=Xenopus
           (Silurana) tropicalis RepID=UPI00006A2233
          Length = 502

 Score =  109 bits (273), Expect = 8e-23
 Identities = 51/118 (43%), Positives = 82/118 (69%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           I+  + +I E+F+ G+P+++++A GS+  DIF +++ +++KGW+LN LQ P+SIHIC+TL
Sbjct: 366 IETELRKIKEIFIFGKPEVSVIALGSNKFDIFRLSNSLTAKGWNLNTLQFPSSIHICLTL 425

Query: 188 QLVPA--VDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
               +     F+KD+KESVE + ++PG  + GL  IYG A  +PDR MV E+   F+D
Sbjct: 426 LHTKSGVAQQFVKDVKESVEVIMQDPGAKTTGLGAIYGMAQTIPDRSMVTEISQAFLD 483

[16][TOP]
>UniRef100_Q1D8D2 Putative sphingosine-1-phosphate lyase n=1 Tax=Myxococcus xanthus
           DK 1622 RepID=Q1D8D2_MYXXD
          Length = 509

 Score =  107 bits (267), Expect = 4e-22
 Identities = 55/119 (46%), Positives = 85/119 (71%), Gaps = 2/119 (1%)
 Frame = +2

Query: 5   SIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT 184
           +I+KGI +I EL V+G P + ++AFGS+ +DIF+V + MS  GW+LN L +P+++H+CVT
Sbjct: 388 AIKKGIRDIPELHVLGDP-LFVIAFGSESVDIFQVMERMSEHGWNLNGLHKPSAVHLCVT 446

Query: 185 LQ-LVPAV-DDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           L+   P V + FL DL+++V+ VK +P    G +AP+YG A  +P RG+V +LL  +MD
Sbjct: 447 LRHTQPGVAEQFLVDLRDAVDYVKSHPS-AKGTMAPVYGMAASVPFRGLVSDLLKKYMD 504

[17][TOP]
>UniRef100_A4QNU7 Sphingosine-1-phosphate lyase 1 n=1 Tax=Danio rerio
           RepID=A4QNU7_DANRE
          Length = 572

 Score =  106 bits (265), Expect = 7e-22
 Identities = 52/120 (43%), Positives = 79/120 (65%), Gaps = 2/120 (1%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           + I+ GI +I  +FV G P++++VA GSD  DIF +++ ++SKGW+LN LQ P+SIHICV
Sbjct: 424 RKIKTGIRKIDGVFVFGDPEVSVVALGSDDFDIFRLSNALTSKGWNLNTLQFPSSIHICV 483

Query: 182 TLQLVPA--VDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           T+    +   + F+ D+K+ V  + KNP   + G+  IYG A  +PDR MV E+   F+D
Sbjct: 484 TMLHTQSGVAEQFISDVKKEVAIIMKNPKEKTTGMGAIYGMAQSIPDRSMVTEVSQGFLD 543

[18][TOP]
>UniRef100_B2W874 Sphingosine-1-phosphate lyase 1 n=1 Tax=Pyrenophora
           tritici-repentis Pt-1C-BFP RepID=B2W874_PYRTR
          Length = 567

 Score =  103 bits (258), Expect = 4e-21
 Identities = 55/133 (41%), Positives = 81/133 (60%), Gaps = 15/133 (11%)
 Frame = +2

Query: 2   KSIQKGIEEIAELF----VVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSI 169
           K I+  I E  EL     ++GRP +++VAF S+ LDI+++ D MSSKGWHLNALQ P +I
Sbjct: 430 KQIETAIREKPELSSDLKIIGRPLVSVVAFLSNTLDIYDIADGMSSKGWHLNALQSPPAI 489

Query: 170 HICVTLQLVPAVDDFLKDLKESVETVKKN-----------PGPISGGLAPIYGAAGKMPD 316
           H+ VTL +V  VD  ++DL E  E V++             G + G  A +YG AG +P+
Sbjct: 490 HVAVTLPIVAVVDKLIEDLVEVTEDVREKERKRIAEGKGAKGAVKGDAAALYGVAGSLPN 549

Query: 317 RGMVQELLVDFMD 355
           + +V++L   F+D
Sbjct: 550 KSVVEDLAKGFLD 562

[19][TOP]
>UniRef100_Q08VE4 Sphingosine-1-phosphate lyase 1 n=1 Tax=Stigmatella aurantiaca
           DW4/3-1 RepID=Q08VE4_STIAU
          Length = 506

 Score =  103 bits (257), Expect = 6e-21
 Identities = 54/120 (45%), Positives = 84/120 (70%), Gaps = 2/120 (1%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           K++++GI  I EL V+G P + ++AFGS  LDI++V + M ++GW LN L +P ++H+CV
Sbjct: 384 KALKEGIAAIPELHVLGDP-LFVIAFGSKTLDIYKVMERMGARGWDLNGLHKPPAVHLCV 442

Query: 182 TLQ-LVPAV-DDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           TL+   P V + FL+DL+ +V  V+ NPG   G +AP+YG AG +P RG++ +LL  +MD
Sbjct: 443 TLRHTQPGVAERFLEDLRAAVAHVQANPGE-KGTMAPVYGMAGTVPFRGVLSDLLKKYMD 501

[20][TOP]
>UniRef100_UPI00016E6E7B UPI00016E6E7B related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E6E7B
          Length = 568

 Score =  103 bits (256), Expect = 8e-21
 Identities = 53/120 (44%), Positives = 78/120 (65%), Gaps = 2/120 (1%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           + I+  I +I  + V+G P++++VA GSD  DIF +++ ++SKGW+LN LQ P SIHIC 
Sbjct: 429 RKIKTEIRKIKGVIVLGDPEISVVALGSDDFDIFRLSNALTSKGWNLNTLQFPASIHICC 488

Query: 182 T-LQLVPAV-DDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           T L   P V D F++D+KE V  + KNP   + G+  IYG A  +PDR +V E+   F+D
Sbjct: 489 TVLHTQPGVADHFIRDVKEQVAIIMKNPKERTTGMGAIYGMAQAIPDRSLVTEISQGFLD 548

[21][TOP]
>UniRef100_UPI0000F2AF77 PREDICTED: similar to sphingosine-1-phosphate lyase n=1
           Tax=Monodelphis domestica RepID=UPI0000F2AF77
          Length = 565

 Score =  102 bits (255), Expect = 1e-20
 Identities = 53/118 (44%), Positives = 78/118 (66%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           ++  +E+I  +FV G P ++++A GS   DIF ++++M++KGW+LN LQ P+SIHIC+T 
Sbjct: 428 LKSELEKIKGIFVFGNPQLSVIALGSRDFDIFRLSNLMTAKGWNLNILQFPSSIHICITM 487

Query: 185 LQLVPAVD-DFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           L   P V   FLKD++ESV  + KNP   + GL  IYG +  + DR MV EL   F+D
Sbjct: 488 LHTRPKVSMQFLKDVRESVTQIMKNPKARTTGLGAIYGMSQTVSDRKMVAELTEAFLD 545

[22][TOP]
>UniRef100_A7RKY4 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7RKY4_NEMVE
          Length = 584

 Score =  102 bits (254), Expect = 1e-20
 Identities = 51/118 (43%), Positives = 75/118 (63%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           I+KG+ ++  L+V G P +++VAFGSD  DI+ +   ++ +GW LN+LQ P +IH+CVT 
Sbjct: 451 IEKGLRDVPGLYVFGEPIVSVVAFGSDKFDIYALGTALTGRGWCLNSLQYPPAIHLCVTL 510

Query: 185 LQLVPAV-DDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           L   P V D FLKD++E    +  +P   + GL  IYG A  +PDR +V EL   F+D
Sbjct: 511 LNTQPGVADRFLKDVRECAAKLLADPNAKTAGLGAIYGMAANIPDRSIVNELACGFLD 568

[23][TOP]
>UniRef100_UPI000194C945 PREDICTED: sphingosine-1-phosphate lyase 1 n=1 Tax=Taeniopygia
           guttata RepID=UPI000194C945
          Length = 700

 Score =  102 bits (253), Expect = 2e-20
 Identities = 44/119 (36%), Positives = 82/119 (68%), Gaps = 2/119 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           ++  + +I  +F+ G+P++++++ GSD  DI+ +++ +++KGW+LN LQ P SIH+C+T 
Sbjct: 562 LESELRKIDSIFIFGKPEVSVLSIGSDTFDIYRLSNFLAAKGWNLNVLQFPPSIHLCITQ 621

Query: 185 LQLVPAV-DDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMDG 358
           L   P V + FLKD+++S++ + K+ G  + G+  IYG A  +PDR +V E+   ++DG
Sbjct: 622 LHTKPGVAEQFLKDVRDSIQDIMKDLGAKTTGMGAIYGMAQSVPDRSLVAEISQAYLDG 680

[24][TOP]
>UniRef100_UPI000155C7D7 PREDICTED: similar to sphingosine-1-phosphate lyase, partial n=1
           Tax=Ornithorhynchus anatinus RepID=UPI000155C7D7
          Length = 560

 Score =  102 bits (253), Expect = 2e-20
 Identities = 52/118 (44%), Positives = 78/118 (66%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           ++  +E I  +F+ G P ++++A GS   DIF +++++++KGW+LN LQ P+SIHIC+T 
Sbjct: 422 LKSELETIKGIFIFGDPQVSVIALGSRDFDIFRLSNVLTAKGWNLNQLQFPSSIHICLTQ 481

Query: 185 LQLVPAV-DDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           L   P V   FLKD++ESV  + KNP   + G+  IYG A  +PDR MV EL   F+D
Sbjct: 482 LHTKPGVATQFLKDVRESVTQIMKNPKAKTTGMGAIYGMAQGVPDRKMVAELSQAFLD 539

[25][TOP]
>UniRef100_Q0UKS0 Putative uncharacterized protein n=1 Tax=Phaeosphaeria nodorum
           RepID=Q0UKS0_PHANO
          Length = 580

 Score =  101 bits (252), Expect = 2e-20
 Identities = 55/133 (41%), Positives = 78/133 (58%), Gaps = 15/133 (11%)
 Frame = +2

Query: 2   KSIQKGIEEIAELF----VVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSI 169
           K I+  I E  EL     V+G+P +++V+F SD +DI+++ D MS KGWHLNALQ P +I
Sbjct: 443 KKIESAIRERPELASDLKVIGKPLVSVVSFLSDTIDIYDIADGMSGKGWHLNALQNPPAI 502

Query: 170 HICVTLQLVPAVDDFLKDLKESVETVKKN-----------PGPISGGLAPIYGAAGKMPD 316
           HI VTL +V  VD  ++DL E  E VK              G + G  A +YG AG +P+
Sbjct: 503 HIAVTLPIVAVVDKLIEDLVEVTEDVKDKERRRIAEGKGAKGAVKGDAAALYGVAGSLPN 562

Query: 317 RGMVQELLVDFMD 355
           + +V +L   F+D
Sbjct: 563 KSVVVDLAKGFLD 575

[26][TOP]
>UniRef100_UPI00017B2759 UPI00017B2759 related cluster n=1 Tax=Tetraodon nigroviridis
           RepID=UPI00017B2759
          Length = 567

 Score =  100 bits (250), Expect = 4e-20
 Identities = 52/120 (43%), Positives = 78/120 (65%), Gaps = 2/120 (1%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           + I+  I +I  + V+G P++++VA GSD  DIF +++ +++KGW+LN LQ P+SIHIC 
Sbjct: 428 RKIKTEIRKIKGVMVLGDPEVSVVALGSDHFDIFRLSNALTAKGWNLNTLQFPSSIHICC 487

Query: 182 T-LQLVPAV-DDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           T L   P V D F+ D+KE V  + KNP   + G+  IYG A  +PDR +V E+   F+D
Sbjct: 488 TVLHTQPGVADRFIGDVKEEVAIIMKNPEERTTGMGAIYGMAQAIPDRSLVTEISRGFLD 547

[27][TOP]
>UniRef100_Q4S3S0 Chromosome 17 SCAF14747, whole genome shotgun sequence. (Fragment)
           n=1 Tax=Tetraodon nigroviridis RepID=Q4S3S0_TETNG
          Length = 595

 Score =  100 bits (250), Expect = 4e-20
 Identities = 52/120 (43%), Positives = 78/120 (65%), Gaps = 2/120 (1%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           + I+  I +I  + V+G P++++VA GSD  DIF +++ +++KGW+LN LQ P+SIHIC 
Sbjct: 458 RKIKTEIRKIKGVMVLGDPEVSVVALGSDHFDIFRLSNALTAKGWNLNTLQFPSSIHICC 517

Query: 182 T-LQLVPAV-DDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           T L   P V D F+ D+KE V  + KNP   + G+  IYG A  +PDR +V E+   F+D
Sbjct: 518 TVLHTQPGVADRFIGDVKEEVAIIMKNPEERTTGMGAIYGMAQAIPDRSLVTEISRGFLD 577

[28][TOP]
>UniRef100_Q5ZMK8 Putative uncharacterized protein n=2 Tax=Gallus gallus
           RepID=Q5ZMK8_CHICK
          Length = 561

 Score =  100 bits (249), Expect = 5e-20
 Identities = 42/119 (35%), Positives = 80/119 (67%), Gaps = 2/119 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           ++  + +I  +F+ G+P++++++ GSD  DI+ +++++++KGW+LN LQ P SIH+C+T 
Sbjct: 423 LESELRKIDSIFIFGKPEVSVLSIGSDTFDIYRLSNLLAAKGWNLNILQFPPSIHLCITQ 482

Query: 188 QLVPA--VDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMDG 358
               +   + FLKD+K+S+E +  N    + G+  IYG A  +PDR +V E+ + ++DG
Sbjct: 483 LHTKSGVAEQFLKDVKDSIEDIMNNLNAKTTGMGAIYGMAQSIPDRSLVAEISLAYLDG 541

[29][TOP]
>UniRef100_C1FD78 Sphingosine-1-phosphate lyase n=1 Tax=Micromonas sp. RCC299
           RepID=C1FD78_9CHLO
          Length = 561

 Score =  100 bits (249), Expect = 5e-20
 Identities = 54/119 (45%), Positives = 76/119 (63%), Gaps = 3/119 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSD--VLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           ++ GI +I  L V+G     +VA+GS   +LDI+ VNDIM +KGWHL+ L  P ++H+C+
Sbjct: 437 LRAGISQIRGLQVLGSDVTMVVAWGSTDPLLDIYVVNDIMITKGWHLSVLHTPAALHMCI 496

Query: 182 TLQLVPAVDDFLKDLKESV-ETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           T   +  V + L DL+E+V E    N   ISGG APIYG AG +PDR +V ++L D  D
Sbjct: 497 TPANLERVPELLSDLREAVDEAQNSNDEGISGGKAPIYGLAGALPDRDLVGDILKDVQD 555

[30][TOP]
>UniRef100_A5UWH0 Pyridoxal-dependent decarboxylase n=1 Tax=Roseiflexus sp. RS-1
           RepID=A5UWH0_ROSS1
          Length = 498

 Score = 97.1 bits (240), Expect = 5e-19
 Identities = 51/118 (43%), Positives = 78/118 (66%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           I+ GIE I EL ++G P + ++AF +  LDI+ + D M+ +GW+LN L  P ++HICVTL
Sbjct: 378 IRTGIEAIPELRILGDP-LWVIAFTATRLDIYRILDRMAQRGWNLNGLHHPPAVHICVTL 436

Query: 188 -QLVPAV-DDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
               P V D F+ DL++SV  V++ P    GG+AP+YG A  +P RG++ +LL  ++D
Sbjct: 437 PHTAPGVADRFIADLRDSVAAVRREP-RARGGMAPVYGMAASLPFRGVIGDLLRRYLD 493

[31][TOP]
>UniRef100_Q6C4B5 YALI0E28237p n=1 Tax=Yarrowia lipolytica RepID=Q6C4B5_YARLI
          Length = 448

 Score = 97.1 bits (240), Expect = 5e-19
 Identities = 46/113 (40%), Positives = 69/113 (61%), Gaps = 1/113 (0%)
 Frame = +2

Query: 23  EEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPA 202
           EEI +L ++G P  +++AFGSD ++I++++D MS KGWHL+ LQ P + H+  T   V A
Sbjct: 332 EEIPDLQIIGDPRASVIAFGSDSVNIYDLSDAMSKKGWHLSTLQNPPAAHVAFTKPAVAA 391

Query: 203 VDDFLKDLKESVETVKK-NPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMDG 358
           VDD + DLK  +  +KK     +  G A  YG AG +   G+   L+  F+DG
Sbjct: 392 VDDLVSDLKSCIIEMKKAGNTKVEDGTAAFYGVAGSIKTAGVADRLVCGFLDG 444

[32][TOP]
>UniRef100_C3Y062 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3Y062_BRAFL
          Length = 566

 Score = 96.7 bits (239), Expect = 7e-19
 Identities = 47/118 (39%), Positives = 78/118 (66%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           I K + +I  +FV G P++++VAFGS+V DI+ V++ +++KGW+LN+LQ P+SIH+C TL
Sbjct: 430 IAKELRKIDGIFVFGEPEVSVVAFGSEVFDIYRVSNTLTAKGWNLNSLQFPSSIHLCCTL 489

Query: 188 -QLVPAVDD-FLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
              +P V D F+ D+K +V     +P   + G   IYG A  +PDR ++ ++   ++D
Sbjct: 490 CHTLPGVTDRFINDVKNAVADALADPQAKTTGQGAIYGMAQSVPDRKIIADIAWGYLD 547

[33][TOP]
>UniRef100_A7TJC3 Putative uncharacterized protein n=1 Tax=Vanderwaltozyma polyspora
           DSM 70294 RepID=A7TJC3_VANPO
          Length = 583

 Score = 96.7 bits (239), Expect = 7e-19
 Identities = 45/120 (37%), Positives = 80/120 (66%), Gaps = 2/120 (1%)
 Frame = +2

Query: 2   KSIQKGIE-EIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHIC 178
           + ++K IE E+ EL ++G P  ++ AF SDV+D++E++D ++ +GWHL+ LQ+P ++H+ 
Sbjct: 438 RKLRKYIENELPELQIIGNPQCSVTAFKSDVIDVYELSDKLAKEGWHLSTLQKPAALHLA 497

Query: 179 VTLQLVPAVDDFLKDLKESVETVKK-NPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           VT   + +VD+    LK ++E +K+ N  P S G + +YG AG +   G+  +L+V F+D
Sbjct: 498 VTKLSINSVDELCTVLKRNIEEMKESNSTPASDGTSALYGIAGSIKTTGVADKLVVGFID 557

[34][TOP]
>UniRef100_UPI0000E224B9 PREDICTED: sphingosine-1-phosphate lyase 1 isoform 2 n=1 Tax=Pan
           troglodytes RepID=UPI0000E224B9
          Length = 488

 Score = 96.3 bits (238), Expect = 9e-19
 Identities = 49/118 (41%), Positives = 72/118 (61%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           ++  +E I  +FV G P ++++A GS   DI+ ++++M++KGW+LN LQ P SIH C+TL
Sbjct: 350 LKSELENIKGIFVFGNPQLSVIALGSRDFDIYRLSNLMTAKGWNLNQLQFPPSIHFCITL 409

Query: 188 --QLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
                     FLKD++ESV  + KNP   + G+  IYG A    DR MV EL   F+D
Sbjct: 410 LHARKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQTTVDRNMVAELSSVFLD 467

[35][TOP]
>UniRef100_UPI0000E224B8 PREDICTED: sphingosine-1-phosphate lyase 1 isoform 6 n=1 Tax=Pan
           troglodytes RepID=UPI0000E224B8
          Length = 568

 Score = 96.3 bits (238), Expect = 9e-19
 Identities = 49/118 (41%), Positives = 72/118 (61%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           ++  +E I  +FV G P ++++A GS   DI+ ++++M++KGW+LN LQ P SIH C+TL
Sbjct: 430 LKSELENIKGIFVFGNPQLSVIALGSRDFDIYRLSNLMTAKGWNLNQLQFPPSIHFCITL 489

Query: 188 --QLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
                     FLKD++ESV  + KNP   + G+  IYG A    DR MV EL   F+D
Sbjct: 490 LHARKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQTTVDRNMVAELSSVFLD 547

[36][TOP]
>UniRef100_UPI0000E224B7 PREDICTED: sphingosine-1-phosphate lyase 1 isoform 1 n=1 Tax=Pan
           troglodytes RepID=UPI0000E224B7
          Length = 569

 Score = 96.3 bits (238), Expect = 9e-19
 Identities = 49/118 (41%), Positives = 72/118 (61%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           ++  +E I  +FV G P ++++A GS   DI+ ++++M++KGW+LN LQ P SIH C+TL
Sbjct: 431 LKSELENIKGIFVFGNPQLSVIALGSRDFDIYRLSNLMTAKGWNLNQLQFPPSIHFCITL 490

Query: 188 --QLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
                     FLKD++ESV  + KNP   + G+  IYG A    DR MV EL   F+D
Sbjct: 491 LHARKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQTTVDRNMVAELSSVFLD 548

[37][TOP]
>UniRef100_UPI0000D9C37C PREDICTED: similar to sphingosine-1-phosphate lyase 1 n=1
           Tax=Macaca mulatta RepID=UPI0000D9C37C
          Length = 633

 Score = 96.3 bits (238), Expect = 9e-19
 Identities = 49/118 (41%), Positives = 72/118 (61%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           ++  +E I  +FV G P ++++A GS   DI+ ++++M++KGW+LN LQ P SIH C+TL
Sbjct: 495 LKSELENIKGIFVFGNPQLSVIALGSRDFDIYRLSNLMTAKGWNLNQLQFPPSIHFCITL 554

Query: 188 --QLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
                     FLKD++ESV  + KNP   + G+  IYG A    DR MV EL   F+D
Sbjct: 555 LHARKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQTTVDRNMVAELSSVFLD 612

[38][TOP]
>UniRef100_A7NKD8 Pyridoxal-dependent decarboxylase n=1 Tax=Roseiflexus castenholzii
           DSM 13941 RepID=A7NKD8_ROSCS
          Length = 498

 Score = 96.3 bits (238), Expect = 9e-19
 Identities = 54/120 (45%), Positives = 78/120 (65%), Gaps = 2/120 (1%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           + I+ GIE I EL V+G P + ++AF S  LDI+ V D M+ +GW+LN L  P +IHICV
Sbjct: 376 RRIRCGIESIPELRVLGDP-LWVIAFASMRLDIYRVLDQMAQRGWNLNGLHHPPAIHICV 434

Query: 182 T-LQLVPAV-DDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           T L   P V D F+ DL+++V  V++ P    GG+AP+YG A  +P R +V +LL  ++D
Sbjct: 435 TLLHTQPGVADRFIADLRDAVAAVRREP-RARGGMAPVYGMAASLPFRSVVSDLLRRYLD 493

[39][TOP]
>UniRef100_B3S4N5 Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens
           RepID=B3S4N5_TRIAD
          Length = 426

 Score = 96.3 bits (238), Expect = 9e-19
 Identities = 49/119 (41%), Positives = 74/119 (62%), Gaps = 2/119 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           I+  I+E+  L+V+G P ++++A GS   DI+++N +MS KGW+LNALQ P SIHIC T+
Sbjct: 304 IKDRIKEVDGLYVLGDPKLSVIAIGSKDFDIYQLNQLMSDKGWNLNALQFPPSIHICCTM 363

Query: 188 QLVP--AVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMDG 358
                  V  FL+D+KE    + + P     G A +YG A  +PDR ++ +L   F+DG
Sbjct: 364 THTQPGVVTKFLRDIKEVAAQLIQEPRKTPIGSAAMYGMAQTIPDRSIITDLTNAFLDG 422

[40][TOP]
>UniRef100_Q5R4G0 Sphingosine-1-phosphate lyase 1 n=1 Tax=Pongo abelii
           RepID=SGPL1_PONAB
          Length = 568

 Score = 96.3 bits (238), Expect = 9e-19
 Identities = 49/118 (41%), Positives = 72/118 (61%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           ++  +E I  +FV G P ++++A GS   DI+ ++++M++KGW+LN LQ P SIH C+TL
Sbjct: 430 LKSELENIKGIFVFGNPQLSVIALGSRDFDIYRLSNLMTAKGWNLNQLQFPPSIHFCITL 489

Query: 188 --QLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
                     FLKD++ESV  + KNP   + G+  IYG A    DR MV EL   F+D
Sbjct: 490 LHARKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQTTVDRNMVAELSSVFLD 547

[41][TOP]
>UniRef100_O95470 Sphingosine-1-phosphate lyase 1 n=1 Tax=Homo sapiens
           RepID=SGPL1_HUMAN
          Length = 568

 Score = 96.3 bits (238), Expect = 9e-19
 Identities = 49/118 (41%), Positives = 72/118 (61%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           ++  +E I  +FV G P ++++A GS   DI+ ++++M++KGW+LN LQ P SIH C+TL
Sbjct: 430 LKSELENIKGIFVFGNPQLSVIALGSRDFDIYRLSNLMTAKGWNLNQLQFPPSIHFCITL 489

Query: 188 --QLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
                     FLKD++ESV  + KNP   + G+  IYG A    DR MV EL   F+D
Sbjct: 490 LHARKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQTTVDRNMVAELSSVFLD 547

[42][TOP]
>UniRef100_B4N5T0 GK17932 n=1 Tax=Drosophila willistoni RepID=B4N5T0_DROWI
          Length = 545

 Score = 95.9 bits (237), Expect = 1e-18
 Identities = 50/113 (44%), Positives = 75/113 (66%), Gaps = 3/113 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           I++G+ +I  +FV G+P  ++VA GS V DIF ++D +   GW+LNALQ P+ IHICVT 
Sbjct: 419 IERGVRQIDGVFVFGKPVTSVVAIGSTVFDIFRLSDSLCKLGWNLNALQFPSGIHICVTD 478

Query: 185 LQLVPAV-DDFLKDLKESVETVKKNPG-PISGGLAPIYGAAGKMPDRGMVQEL 337
           +   P V D F+ DL+  V  + K+PG P+ G +A +YG A  +PDR ++ E+
Sbjct: 479 MHTKPGVADKFIADLRSCVAEIMKDPGVPVEGKMA-LYGMAQSIPDRSVIGEV 530

[43][TOP]
>UniRef100_C5DM58 KLTH0G06182p n=1 Tax=Lachancea thermotolerans CBS 6340
           RepID=C5DM58_LACTC
          Length = 561

 Score = 95.9 bits (237), Expect = 1e-18
 Identities = 46/113 (40%), Positives = 73/113 (64%), Gaps = 2/113 (1%)
 Frame = +2

Query: 23  EEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPA 202
           EEI EL ++G P  ++VAF SD +D+ E++D ++ +GWHL+ALQ P ++H+ VT    PA
Sbjct: 440 EEIPELCIIGDPLCSVVAFTSDQIDVHELSDKLAKQGWHLSALQNPPALHLAVTWLTRPA 499

Query: 203 VDDFLKDLKESVETVKKNPG--PISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           + + ++ L+E V+ +   P   P S G + +YG AG +   G+V  LLV F+D
Sbjct: 500 LPELMRTLQEVVKELSSEPNKKPSSDGTSALYGVAGSVKTSGVVDRLLVGFLD 552

[44][TOP]
>UniRef100_UPI00005872F7 PREDICTED: hypothetical protein n=1 Tax=Strongylocentrotus
           purpuratus RepID=UPI00005872F7
          Length = 422

 Score = 95.5 bits (236), Expect = 2e-18
 Identities = 44/120 (36%), Positives = 77/120 (64%), Gaps = 2/120 (1%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           + + + + +I  LFV G P++++V  GS V +I+ ++  ++ +GW+LN+LQ P+S H+CV
Sbjct: 294 RKVAEEVGKIPGLFVYGNPEVSVVGVGSKVFNIYRLSGALTERGWNLNSLQFPSSFHLCV 353

Query: 182 TL-QLVPAV-DDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           TL Q  P V + F++D+KE  E + K P   + G A +YG A  +PDR +V ++   ++D
Sbjct: 354 TLRQTFPGVAEQFIQDVKECTEEIMKTPNEKASGSAALYGTAQAIPDRSLVTDMARGYLD 413

[45][TOP]
>UniRef100_UPI0001B79B0A Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (SPL)
           (Sphingosine-1-phosphate aldolase). n=1 Tax=Rattus
           norvegicus RepID=UPI0001B79B0A
          Length = 568

 Score = 95.5 bits (236), Expect = 2e-18
 Identities = 47/118 (39%), Positives = 73/118 (61%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           ++  +E I  +F++G P ++++A GS+  DI+ ++++MS+KGW+ N LQ P SIH C+TL
Sbjct: 430 LKSELENIKNIFILGDPQLSVIALGSNDFDIYRLSNMMSAKGWNFNYLQFPRSIHFCITL 489

Query: 188 --QLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
                     FLKD++ESV  + KNP   + G+  IYG A    DR MV E+   F+D
Sbjct: 490 VHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQATIDRKMVAEISSVFLD 547

[46][TOP]
>UniRef100_Q8CHN6 Sphingosine-1-phosphate lyase 1 n=1 Tax=Rattus norvegicus
           RepID=SGPL1_RAT
          Length = 568

 Score = 95.5 bits (236), Expect = 2e-18
 Identities = 47/118 (39%), Positives = 73/118 (61%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           ++  +E I  +F++G P ++++A GS+  DI+ ++++MS+KGW+ N LQ P SIH C+TL
Sbjct: 430 LKSELENIKNIFILGDPQLSVIALGSNDFDIYRLSNMMSAKGWNFNYLQFPRSIHFCITL 489

Query: 188 --QLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
                     FLKD++ESV  + KNP   + G+  IYG A    DR MV E+   F+D
Sbjct: 490 VHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQATIDRKMVAEISSVFLD 547

[47][TOP]
>UniRef100_B4KQG4 GI21004 n=1 Tax=Drosophila mojavensis RepID=B4KQG4_DROMO
          Length = 544

 Score = 95.1 bits (235), Expect = 2e-18
 Identities = 49/113 (43%), Positives = 75/113 (66%), Gaps = 3/113 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           I++G+ +I  +FV G+P  +++A GS+V DIF ++D +   GW+LNALQ P+ IHICVT 
Sbjct: 419 IERGVRQIDGIFVFGKPATSVIAIGSNVFDIFRLSDALCKLGWNLNALQFPSGIHICVTD 478

Query: 185 LQLVPAV-DDFLKDLKESVETVKKNPG-PISGGLAPIYGAAGKMPDRGMVQEL 337
           +   P V D FL DL+     + K+PG P+ G +A +YG A  +PDR ++ E+
Sbjct: 479 MHTRPGVADKFLADLRTCTAEIMKDPGQPVVGKMA-LYGMAQSIPDRSVIGEV 530

[48][TOP]
>UniRef100_UPI00018614E7 hypothetical protein BRAFLDRAFT_277715 n=1 Tax=Branchiostoma
           floridae RepID=UPI00018614E7
          Length = 566

 Score = 94.7 bits (234), Expect = 3e-18
 Identities = 46/118 (38%), Positives = 78/118 (66%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           I K +++I  +FV G P++++VAFGS+V DI+ V++ +++KGW+LN+ Q P+SIH+C TL
Sbjct: 430 IAKELKKIDGIFVFGEPEVSVVAFGSEVFDIYRVSNTLTAKGWNLNSQQFPSSIHLCCTL 489

Query: 188 -QLVPAVDD-FLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
              +P V D F+ D+K +V     +P   + G   IYG A  +PDR ++ ++   ++D
Sbjct: 490 CHTLPGVTDRFINDVKNAVADALADPQAKTTGQGAIYGMAQSVPDRKIIADIAWGYLD 547

[49][TOP]
>UniRef100_UPI00017F051B PREDICTED: similar to sphingosine-1-phosphate lyase 1 n=1 Tax=Sus
           scrofa RepID=UPI00017F051B
          Length = 568

 Score = 94.0 bits (232), Expect = 5e-18
 Identities = 49/114 (42%), Positives = 69/114 (60%), Gaps = 2/114 (1%)
 Frame = +2

Query: 20  IEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL--QL 193
           +E I  +FV G P ++++A GS   DIF + ++M++KGW+LN LQ P SIH C+TL    
Sbjct: 434 LENIKGIFVFGNPQLSVIALGSRDFDIFRLFNLMTAKGWNLNQLQFPPSIHFCITLVHTR 493

Query: 194 VPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
                 FLKD++ESV  + KNP   + G+  IYG A    DR +V EL   F+D
Sbjct: 494 KRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQATIDRNLVAELSSFFLD 547

[50][TOP]
>UniRef100_UPI000155D8B9 PREDICTED: sphingosine-1-phosphate lyase 1 n=1 Tax=Equus caballus
           RepID=UPI000155D8B9
          Length = 568

 Score = 94.0 bits (232), Expect = 5e-18
 Identities = 48/118 (40%), Positives = 72/118 (61%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           ++  +E+I  +FV G P ++++A GS   DI+ + ++M++KGW+LN LQ P SIH C+TL
Sbjct: 430 LKSELEKIKGIFVFGNPQLSVIALGSRDFDIYRLFNLMTAKGWNLNQLQFPPSIHFCITL 489

Query: 188 --QLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
                     FLKD++ESV  + KNP   + G+  IYG A    DR +V EL   F+D
Sbjct: 490 VHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQTTVDRNLVAELSSVFLD 547

[51][TOP]
>UniRef100_Q8R0X7 Sphingosine-1-phosphate lyase 1 n=2 Tax=Mus musculus
           RepID=SGPL1_MOUSE
          Length = 568

 Score = 94.0 bits (232), Expect = 5e-18
 Identities = 48/127 (37%), Positives = 76/127 (59%), Gaps = 2/127 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           ++  +E I  +F+ G P ++++A GS+  DI+ ++++MS+KGW+ N LQ P SIH C+TL
Sbjct: 430 LKSELENIKNIFIFGDPQLSVIALGSNDFDIYRLSNMMSAKGWNFNYLQFPRSIHFCITL 489

Query: 188 --QLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMDGT 361
                     FLKD++ESV  + KNP   + G+  IYG A    DR +V E+   F+D  
Sbjct: 490 VHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQATIDRKLVAEISSVFLD-- 547

Query: 362 C*WCSQP 382
           C + + P
Sbjct: 548 CLYTTDP 554

[52][TOP]
>UniRef100_Q4FK38 Sgpl1 protein n=1 Tax=Mus musculus RepID=Q4FK38_MOUSE
          Length = 568

 Score = 94.0 bits (232), Expect = 5e-18
 Identities = 48/127 (37%), Positives = 76/127 (59%), Gaps = 2/127 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           ++  +E I  +F+ G P ++++A GS+  DI+ ++++MS+KGW+ N LQ P SIH C+TL
Sbjct: 430 LKSELENIKNIFIFGDPQLSVIALGSNDFDIYRLSNMMSAKGWNFNYLQFPRSIHFCITL 489

Query: 188 --QLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMDGT 361
                     FLKD++ESV  + KNP   + G+  IYG A    DR +V E+   F+D  
Sbjct: 490 VHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQATIDRKLVAEISSVFLD-- 547

Query: 362 C*WCSQP 382
           C + + P
Sbjct: 548 CLYTTDP 554

[53][TOP]
>UniRef100_Q3UDJ2 Putative uncharacterized protein n=1 Tax=Mus musculus
           RepID=Q3UDJ2_MOUSE
          Length = 568

 Score = 94.0 bits (232), Expect = 5e-18
 Identities = 48/127 (37%), Positives = 76/127 (59%), Gaps = 2/127 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           ++  +E I  +F+ G P ++++A GS+  DI+ ++++MS+KGW+ N LQ P SIH C+TL
Sbjct: 430 LKSELENIKNIFIFGDPQLSVIALGSNDFDIYRLSNMMSAKGWNFNYLQFPRSIHFCITL 489

Query: 188 --QLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMDGT 361
                     FLKD++ESV  + KNP   + G+  IYG A    DR +V E+   F+D  
Sbjct: 490 VHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQATIDRKLVAEISSVFLD-- 547

Query: 362 C*WCSQP 382
           C + + P
Sbjct: 548 CLYTTDP 554

[54][TOP]
>UniRef100_C1MXR5 Sphingosine-1-phosphate lyase n=1 Tax=Micromonas pusilla CCMP1545
           RepID=C1MXR5_9CHLO
          Length = 561

 Score = 94.0 bits (232), Expect = 5e-18
 Identities = 52/119 (43%), Positives = 72/119 (60%), Gaps = 3/119 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSD--VLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           ++ G+ EI  L V+G     +VA+GS    L+I+ VND+M  KGWHL+ LQ P ++H+C+
Sbjct: 437 LRAGLSEIDGLKVLGEDVSMVVAWGSSDPSLNIYTVNDVMVKKGWHLSVLQAPPALHMCL 496

Query: 182 TLQLVPAVDDFLKDLKESV-ETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           T   V +V     DL  +V ET     G + GG APIYG AG +PDRG V ++L D  D
Sbjct: 497 TSANVASVRQLCVDLAIAVKETRALGKGKVDGGKAPIYGLAGGLPDRGTVGDILKDVQD 555

[55][TOP]
>UniRef100_UPI0000EB3D58 Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (hSPL)
           (Sphingosine-1-phosphate aldolase). n=1 Tax=Canis lupus
           familiaris RepID=UPI0000EB3D58
          Length = 568

 Score = 93.2 bits (230), Expect = 8e-18
 Identities = 48/118 (40%), Positives = 71/118 (60%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           ++  +E I  +FV G P ++++A GS   DI+ + ++M++KGW+LN LQ P SIH C+TL
Sbjct: 430 LKSELETIKGIFVFGNPQLSVIALGSRDFDIYRLFNLMTAKGWNLNQLQFPPSIHFCITL 489

Query: 188 --QLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
                     FLKD++ESV  + KNP   + G+  IYG A    DR +V EL   F+D
Sbjct: 490 VHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQTTVDRNLVAELSSVFLD 547

[56][TOP]
>UniRef100_UPI00005A07E0 PREDICTED: similar to sphingosine-1-phosphate lyase 1 n=1 Tax=Canis
           lupus familiaris RepID=UPI00005A07E0
          Length = 568

 Score = 93.2 bits (230), Expect = 8e-18
 Identities = 48/118 (40%), Positives = 71/118 (60%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           ++  +E I  +FV G P ++++A GS   DI+ + ++M++KGW+LN LQ P SIH C+TL
Sbjct: 430 LKSELETIKGIFVFGNPQLSVIALGSRDFDIYRLFNLMTAKGWNLNQLQFPPSIHFCITL 489

Query: 188 --QLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
                     FLKD++ESV  + KNP   + G+  IYG A    DR +V EL   F+D
Sbjct: 490 VHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQTTVDRNLVAELSSVFLD 547

[57][TOP]
>UniRef100_Q290S2 GA21426 n=1 Tax=Drosophila pseudoobscura pseudoobscura
           RepID=Q290S2_DROPS
          Length = 545

 Score = 93.2 bits (230), Expect = 8e-18
 Identities = 47/113 (41%), Positives = 73/113 (64%), Gaps = 3/113 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           I++G+ +I  LFV G+P  +++A GS+V DIF ++D +   GW+LNALQ P+ IHICVT 
Sbjct: 419 IERGVRDIDGLFVFGKPATSVIALGSNVFDIFRLSDSLCKLGWNLNALQFPSGIHICVTD 478

Query: 188 QLVPA--VDDFLKDLKESVETVKKNPG-PISGGLAPIYGAAGKMPDRGMVQEL 337
               A   D F+ D++     + K+PG P+ G +A +YG A  +PDR ++ E+
Sbjct: 479 MHTQAGVADKFIADVRSCTAEIMKDPGQPVVGKMA-LYGMAQSIPDRSVIGEV 530

[58][TOP]
>UniRef100_B4P8H4 GE14215 n=1 Tax=Drosophila yakuba RepID=B4P8H4_DROYA
          Length = 545

 Score = 93.2 bits (230), Expect = 8e-18
 Identities = 46/113 (40%), Positives = 76/113 (67%), Gaps = 3/113 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           I++G+ +I  +F+ G+P  +++A GS+V DIF ++D +   GW+LNALQ P+ IH+CVT 
Sbjct: 419 IERGLRDIDGVFIFGKPATSVIALGSNVFDIFRLSDSLCKLGWNLNALQFPSGIHLCVTD 478

Query: 185 LQLVPAV-DDFLKDLKESVETVKKNPG-PISGGLAPIYGAAGKMPDRGMVQEL 337
           +   P V D F+ D++  V  + K+PG P+ G +A +YG A  +PDR ++ E+
Sbjct: 479 MHTQPGVADKFIADVRSCVAEIMKDPGQPVVGKMA-LYGMAQSIPDRSVIGEV 530

[59][TOP]
>UniRef100_B4GBB4 GL10551 n=1 Tax=Drosophila persimilis RepID=B4GBB4_DROPE
          Length = 527

 Score = 93.2 bits (230), Expect = 8e-18
 Identities = 47/113 (41%), Positives = 73/113 (64%), Gaps = 3/113 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           I++G+ +I  LFV G+P  +++A GS+V DIF ++D +   GW+LNALQ P+ IHICVT 
Sbjct: 401 IERGVRDIDGLFVFGKPATSVIALGSNVFDIFRLSDSLCKLGWNLNALQFPSGIHICVTD 460

Query: 188 QLVPA--VDDFLKDLKESVETVKKNPG-PISGGLAPIYGAAGKMPDRGMVQEL 337
               A   D F+ D++     + K+PG P+ G +A +YG A  +PDR ++ E+
Sbjct: 461 MHTQAGVADKFIADVRSCTAEIMKDPGQPVVGKMA-LYGMAQSIPDRSVIGEV 512

[60][TOP]
>UniRef100_UPI000180C1A9 PREDICTED: similar to sphingosine-1-phosphate lyase 1 n=1 Tax=Ciona
           intestinalis RepID=UPI000180C1A9
          Length = 562

 Score = 92.8 bits (229), Expect = 1e-17
 Identities = 47/118 (39%), Positives = 76/118 (64%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           I++G+ +I  ++V+G+P+M++VA GS   D+F ++  +  +GW+LN LQ P SIHIC T+
Sbjct: 427 IEQGLRKIEYIYVLGKPEMSVVALGSLDFDVFRLSTELVKRGWNLNNLQFPASIHICCTM 486

Query: 188 -QLVPAV-DDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
               P V D  L+D++ESV+ +  +P   + G   IYG A  +PDR +V E+   F+D
Sbjct: 487 PHTHPGVADRLLQDIRESVDIIMSDPKAKATGAGAIYGMAQSIPDRSIVTEISHGFID 544

[61][TOP]
>UniRef100_A6GEB7 Putative sphingosine-1-phosphate lyase n=1 Tax=Plesiocystis
           pacifica SIR-1 RepID=A6GEB7_9DELT
          Length = 509

 Score = 92.4 bits (228), Expect = 1e-17
 Identities = 53/122 (43%), Positives = 77/122 (63%), Gaps = 4/122 (3%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAF--GSDVLDIFEVNDIMSSKGWHLNALQRPNSIHI 175
           + I++GI+ I  L V+G P + +V+F  G + L+I+EV D M  K W+LN L RP  +H+
Sbjct: 385 QKIRRGIDAILGLKVLGDP-LWVVSFASGEEGLNIYEVLDAMGKKHWNLNGLHRPPCVHL 443

Query: 176 CVTLQLVP--AVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDF 349
            VTL+       + FL DL+E+VE  + NPG    G+APIYG AG +P RG V +LL  +
Sbjct: 444 AVTLRHTKEGVAERFLDDLREAVEHTRANPGE-GSGMAPIYGLAGTIPARGAVSDLLEMY 502

Query: 350 MD 355
           +D
Sbjct: 503 LD 504

[62][TOP]
>UniRef100_A5D788 SGPL1 protein n=1 Tax=Bos taurus RepID=A5D788_BOVIN
          Length = 568

 Score = 92.4 bits (228), Expect = 1e-17
 Identities = 47/118 (39%), Positives = 71/118 (60%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           ++  +E I  +FV G P ++++A GS   DI+ + ++M++KGW+LN LQ P S+H C+TL
Sbjct: 430 LKSELENIKGIFVFGNPQLSVIALGSRDFDIYRLFNLMNAKGWNLNQLQFPPSLHFCITL 489

Query: 188 --QLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
                     FLKD++ESV  + KNP   + G+  IYG A    DR +V EL   F+D
Sbjct: 490 VHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQATIDRNLVAELSSVFLD 547

[63][TOP]
>UniRef100_B4QIK3 GD25496 n=2 Tax=melanogaster subgroup RepID=B4QIK3_DROSI
          Length = 545

 Score = 92.4 bits (228), Expect = 1e-17
 Identities = 45/113 (39%), Positives = 75/113 (66%), Gaps = 3/113 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           I++G+ +I  +F+ G+P  +++A GS+V DIF ++D +   GW+LNALQ P+ IH+CVT 
Sbjct: 419 IERGVRDIDGIFIFGKPATSVIALGSNVFDIFRLSDSLCKLGWNLNALQFPSGIHLCVTD 478

Query: 185 LQLVPAV-DDFLKDLKESVETVKKNPG-PISGGLAPIYGAAGKMPDRGMVQEL 337
           +   P V D F+ D++     + K+PG P+ G +A +YG A  +PDR ++ E+
Sbjct: 479 MHTQPGVADKFIADVRSCTAEIMKDPGQPVVGKMA-LYGMAQSIPDRSVIGEV 530

[64][TOP]
>UniRef100_B3NP20 GG22218 n=1 Tax=Drosophila erecta RepID=B3NP20_DROER
          Length = 545

 Score = 92.4 bits (228), Expect = 1e-17
 Identities = 45/113 (39%), Positives = 75/113 (66%), Gaps = 3/113 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           I++G+ +I  +F+ G+P  +++A GS+V DIF ++D +   GW+LNALQ P+ IH+CVT 
Sbjct: 419 IERGVRDINGIFIFGKPATSVIALGSNVFDIFRLSDSLCKLGWNLNALQFPSGIHLCVTD 478

Query: 185 LQLVPAV-DDFLKDLKESVETVKKNPG-PISGGLAPIYGAAGKMPDRGMVQEL 337
           +   P V D F+ D++     + K+PG P+ G +A +YG A  +PDR ++ E+
Sbjct: 479 MHTQPGVADKFIADVRSCTAEIMKDPGQPVVGKMA-LYGMAQSIPDRSVIGEV 530

[65][TOP]
>UniRef100_B3MD62 GF13423 n=1 Tax=Drosophila ananassae RepID=B3MD62_DROAN
          Length = 545

 Score = 92.4 bits (228), Expect = 1e-17
 Identities = 47/115 (40%), Positives = 73/115 (63%), Gaps = 3/115 (2%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           + I++G+ +I  +FV G+P  +++A GS   DIF ++D +   GW+LNALQ P+ IHICV
Sbjct: 417 RHIERGVRDINGIFVFGKPATSVIALGSKKFDIFRLSDALCKLGWNLNALQFPSGIHICV 476

Query: 182 T-LQLVPAV-DDFLKDLKESVETVKKNPG-PISGGLAPIYGAAGKMPDRGMVQEL 337
           T +   P V D F+ D+K     + K+PG P+ G  A +YG A  +PDR ++ E+
Sbjct: 477 TDMHTQPGVADKFIADVKSCTAEIMKDPGQPVQGKFA-LYGMAQSIPDRSVIGEV 530

[66][TOP]
>UniRef100_Q6FSD9 Strain CBS138 chromosome H complete sequence n=1 Tax=Candida
           glabrata RepID=Q6FSD9_CANGA
          Length = 565

 Score = 92.4 bits (228), Expect = 1e-17
 Identities = 41/112 (36%), Positives = 74/112 (66%), Gaps = 2/112 (1%)
 Frame = +2

Query: 26  EIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAV 205
           ++ +L V+G P +++V+F S+ L+I+E+ D ++  GWHLNALQ+P ++H+ +T   VP +
Sbjct: 446 KLPQLEVLGDPKLSVVSFSSNKLNIYELADRLAKSGWHLNALQKPAALHLAITTLSVPTI 505

Query: 206 DDFLKDLKESVETVKKNP--GPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           D F++ L E+VE +  +P   P + G + +YG AG +   G+  +L+  F+D
Sbjct: 506 DTFIETLTEAVEQMSADPTSTPSTEGTSALYGVAGSVKTTGVADKLITAFLD 557

[67][TOP]
>UniRef100_Q9V7Y2 Sphingosine-1-phosphate lyase n=1 Tax=Drosophila melanogaster
           RepID=SGPL_DROME
          Length = 545

 Score = 92.4 bits (228), Expect = 1e-17
 Identities = 45/113 (39%), Positives = 75/113 (66%), Gaps = 3/113 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           I++G+ +I  +F+ G+P  +++A GS+V DIF ++D +   GW+LNALQ P+ IH+CVT 
Sbjct: 419 IERGVRDIDGIFIFGKPATSVIALGSNVFDIFRLSDSLCKLGWNLNALQFPSGIHLCVTD 478

Query: 185 LQLVPAV-DDFLKDLKESVETVKKNPG-PISGGLAPIYGAAGKMPDRGMVQEL 337
           +   P V D F+ D++     + K+PG P+ G +A +YG A  +PDR ++ E+
Sbjct: 479 MHTQPGVADKFIADVRSCTAEIMKDPGQPVVGKMA-LYGMAQSIPDRSVIGEV 530

[68][TOP]
>UniRef100_B4LKG7 GJ20717 n=1 Tax=Drosophila virilis RepID=B4LKG7_DROVI
          Length = 544

 Score = 92.0 bits (227), Expect = 2e-17
 Identities = 46/113 (40%), Positives = 72/113 (63%), Gaps = 3/113 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           I++G+ +I  +FV G+P  +++A GS+V DIF ++D +   GW+LN LQ P+ IHIC+T 
Sbjct: 419 IERGVRQIDGIFVFGKPATSVIAMGSNVFDIFRLSDALCKLGWNLNPLQFPSGIHICITD 478

Query: 188 QLVPA--VDDFLKDLKESVETVKKNPG-PISGGLAPIYGAAGKMPDRGMVQEL 337
               A   D FL DL+     + K+PG P+ G +A +YG A  +PDR ++ E+
Sbjct: 479 MHTQAGVADKFLADLRTCTAEIMKDPGQPVVGKMA-LYGMAQSIPDRSVIGEV 530

[69][TOP]
>UniRef100_A6SSH1 Putative uncharacterized protein n=1 Tax=Botryotinia fuckeliana
           B05.10 RepID=A6SSH1_BOTFB
          Length = 157

 Score = 92.0 bits (227), Expect = 2e-17
 Identities = 50/119 (42%), Positives = 72/119 (60%), Gaps = 11/119 (9%)
 Frame = +2

Query: 32  AELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDD 211
           A+L V+G+P +++VAF S  LDI+++ D MS KGWHLN+LQ P +IH+ VTL +V   + 
Sbjct: 34  ADLHVLGKPLVSVVAFTSKTLDIYDIADAMSGKGWHLNSLQNPPAIHVAVTLPIVKVWEK 93

Query: 212 FLKDL---------KESVETV--KKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
            ++DL         KE V  V  K   G   G  A +YG AG +P++ +V EL   F+D
Sbjct: 94  LIEDLIAVVEGEKEKERVRIVEGKGAKGKSLGDSAALYGVAGSLPNKSVVVELASGFLD 152

[70][TOP]
>UniRef100_A4RSX4 Sphingosine-1-phosphate lyase n=1 Tax=Ostreococcus lucimarinus
           CCE9901 RepID=A4RSX4_OSTLU
          Length = 532

 Score = 91.3 bits (225), Expect = 3e-17
 Identities = 47/118 (39%), Positives = 75/118 (63%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSD--VLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           ++K + +   L ++GR    +VA+ +     +++ +NDI+SSKGW L  LQ P+++H C+
Sbjct: 410 LRKAVADTDGLELIGRHATMVVAWRTTDRTNNVYVLNDILSSKGWRLAVLQNPSALHFCI 469

Query: 182 TLQLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           T   + +VD  + DLK++V+T  +    I GG APIYG A  +PDRG+V+ELL D  D
Sbjct: 470 TPANISSVDALIDDLKQAVQT-SRTLDKIPGGKAPIYGLAHGLPDRGVVKELLRDIQD 526

[71][TOP]
>UniRef100_C5E100 ZYRO0G16918p n=1 Tax=Zygosaccharomyces rouxii CBS 732
           RepID=C5E100_ZYGRC
          Length = 570

 Score = 91.3 bits (225), Expect = 3e-17
 Identities = 42/113 (37%), Positives = 71/113 (62%), Gaps = 2/113 (1%)
 Frame = +2

Query: 23  EEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPA 202
           +E+ EL ++G P   +V+F SD L+++E+ D +S  GWHL+ALQ+P ++HI VT   V +
Sbjct: 448 KELPELQIIGDPLCCVVSFKSDQLNVYELGDKLSKMGWHLSALQKPPALHIAVTKLSVSS 507

Query: 203 VDDFLKDLKESVETVKKNPG--PISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           +D  + DLK  V  +KKNP   P + G + +YG A  +   G+  +++  ++D
Sbjct: 508 IDKLVSDLKTMVNEMKKNPNQKPANDGTSALYGVASSIKTTGVADKVVAGYLD 560

[72][TOP]
>UniRef100_B4J547 GH20882 n=1 Tax=Drosophila grimshawi RepID=B4J547_DROGR
          Length = 544

 Score = 90.9 bits (224), Expect = 4e-17
 Identities = 43/112 (38%), Positives = 70/112 (62%), Gaps = 2/112 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           I++G+ +I  +F+ G+P  +++A GS+V DIF ++D +   GW+LN LQ P+ IHIC+T 
Sbjct: 419 IERGVRQIDGIFIFGKPATSVIAMGSNVFDIFRLSDALCKLGWNLNPLQFPSGIHICITD 478

Query: 185 LQLVPAV-DDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQEL 337
           +   P V D F+ DL+     + K+PG    G   +YG A  +PDR ++ E+
Sbjct: 479 MHTKPGVADKFVADLRTCTAEIMKDPGQPVVGKFALYGMAQSIPDRSVIGEV 530

[73][TOP]
>UniRef100_Q6CTS1 KLLA0C10505p n=1 Tax=Kluyveromyces lactis RepID=Q6CTS1_KLULA
          Length = 582

 Score = 90.1 bits (222), Expect = 7e-17
 Identities = 43/113 (38%), Positives = 74/113 (65%), Gaps = 2/113 (1%)
 Frame = +2

Query: 23  EEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPA 202
           +EI EL ++G P  ++++F S+ +DI+E++D +S  GWHL+ALQ P+SIH+ +T   + +
Sbjct: 459 KEIPELQILGDPLCSVISFTSNKIDIYELSDTLSKSGWHLSALQNPSSIHLALTKLSLKS 518

Query: 203 VDDFLKDLKESVETVKKNPG--PISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           VD+    LK +V+ +K++P   P S G + +YG AG +   G+   L+  F+D
Sbjct: 519 VDELKHLLKSTVDKMKQSPDAKPSSDGTSALYGVAGSVKTVGVADRLIEGFLD 571

[74][TOP]
>UniRef100_Q0CJA5 Putative uncharacterized protein n=1 Tax=Aspergillus terreus
           NIH2624 RepID=Q0CJA5_ASPTN
          Length = 565

 Score = 90.1 bits (222), Expect = 7e-17
 Identities = 47/119 (39%), Positives = 74/119 (62%), Gaps = 11/119 (9%)
 Frame = +2

Query: 32  AELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDD 211
           +ELFV+G P +++VAFG+  LD++ + D M +KGWHLNA+Q P +IH+ VT+ +V     
Sbjct: 443 SELFVLGNPLVSVVAFGARHLDVYRIADGMLNKGWHLNAMQDPPAIHVAVTMPIVKVWMR 502

Query: 212 FLKDLKESVETVKKN-----------PGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
            + DL+  V++ +K            P P +G  A +YG AG +P++G+V EL   F+D
Sbjct: 503 LIADLEAVVQSERKEVEKRLEAGESIPEP-TGNSATLYGVAGSLPNKGIVVELTRGFLD 560

[75][TOP]
>UniRef100_A7EYG6 Putative uncharacterized protein n=1 Tax=Sclerotinia sclerotiorum
           1980 UF-70 RepID=A7EYG6_SCLS1
          Length = 529

 Score = 90.1 bits (222), Expect = 7e-17
 Identities = 48/118 (40%), Positives = 72/118 (61%), Gaps = 11/118 (9%)
 Frame = +2

Query: 35  ELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDDF 214
           +L ++G+P +++VAF S  LDI+++ D MS+KGWHLN+LQ P +IH+ VTL +V   +  
Sbjct: 407 DLHILGKPLVSVVAFTSKTLDIYDIADAMSAKGWHLNSLQSPPAIHVAVTLPIVKVREKL 466

Query: 215 LKDL---------KESVETV--KKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           ++DL         KE V  V  K   G   G  A +YG AG +P++ +V EL   F+D
Sbjct: 467 IEDLIAVVEGEKEKERVRIVEGKGAKGKSLGDSAALYGVAGSLPNKSVVVELASGFLD 524

[76][TOP]
>UniRef100_B7G9X7 Predicted protein (Fragment) n=1 Tax=Phaeodactylum tricornutum CCAP
           1055/1 RepID=B7G9X7_PHATR
          Length = 442

 Score = 89.7 bits (221), Expect = 9e-17
 Identities = 49/121 (40%), Positives = 72/121 (59%), Gaps = 1/121 (0%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           ++I  GI+ +  + ++      +V+F S+ +DI+ + D M+  GW+LNALQ P S+HICV
Sbjct: 320 RAIADGIQLVRGVKLLTPKPFMVVSFTSNEMDIYRIQDYMTKAGWNLNALQSPASVHICV 379

Query: 182 TLQLVPAVDDFLKDLKESVETVK-KNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMDG 358
           TL +VP VD FL+DLK S+  V+ +  G    G A +YG  G +P  G V   L  F D 
Sbjct: 380 TLNVVPKVDSFLRDLKMSINQVRNEGKGGRKKGTAGVYGTVGSLP-AGPVDYSLRAFTDL 438

Query: 359 T 361
           T
Sbjct: 439 T 439

[77][TOP]
>UniRef100_C9SKG3 Sphingosine-1-phosphate lyase n=1 Tax=Verticillium albo-atrum
           VaMs.102 RepID=C9SKG3_9PEZI
          Length = 566

 Score = 89.7 bits (221), Expect = 9e-17
 Identities = 45/119 (37%), Positives = 72/119 (60%), Gaps = 11/119 (9%)
 Frame = +2

Query: 32  AELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDD 211
           +EL +VGRP ++++AF +  LDI+++ D MS+KGWHLNALQ P +IH+ VTL +    + 
Sbjct: 443 SELEIVGRPLVSVMAFTARNLDIYDIADAMSTKGWHLNALQNPPAIHVAVTLPITKVWEK 502

Query: 212 FLKDLKESVETVKKN-----------PGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
            + DL+  VE  ++             G   G  A +YG AG +P++ +V +L+  F+D
Sbjct: 503 LMADLEAVVEAEREKERVRIVEGKGAKGTAKGDSAALYGVAGSLPNKSVVVDLVNGFLD 561

[78][TOP]
>UniRef100_B7PHK6 Sphingosine phosphate lyase, putative n=1 Tax=Ixodes scapularis
           RepID=B7PHK6_IXOSC
          Length = 475

 Score = 89.0 bits (219), Expect = 1e-16
 Identities = 45/115 (39%), Positives = 71/115 (61%), Gaps = 3/115 (2%)
 Frame = +2

Query: 20  IEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMS-SKGWHLNALQRPNSIHICVTLQLV 196
           + E+  ++V+G PD ++VA GS V DIF++ + ++  +GW+LN LQ P   H+CVTL  V
Sbjct: 350 VSEVPGIYVIGSPDTSVVAIGSHVFDIFQLMEKLTHQRGWNLNPLQYPAGFHLCVTLLHV 409

Query: 197 P--AVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
                D F+ D++E    + K+P   S G A IYG A  +PDR +V++L   ++D
Sbjct: 410 SEKVADRFVNDVRELTAEIMKDPPKPSTGQAAIYGMAQSLPDRTVVEDLARAYID 464

[79][TOP]
>UniRef100_UPI000186EA0D Sply, sphingosine-phosphate lyase, putative n=1 Tax=Pediculus
           humanus corporis RepID=UPI000186EA0D
          Length = 554

 Score = 87.0 bits (214), Expect = 6e-16
 Identities = 46/120 (38%), Positives = 70/120 (58%), Gaps = 2/120 (1%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           K I+  ++EI E+FV G P  ++VA GS+   I+ ++D +S  GW+LN LQ P  IH+CV
Sbjct: 415 KYIENKLKEIDEIFVFGSPITSVVAIGSNTFHIYRLSDALSKCGWNLNPLQYPPGIHLCV 474

Query: 182 T-LQLVPAV-DDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           T L     V + F++D+K  V  + KNP     G   +YG +  +PDR +V +    F+D
Sbjct: 475 TNLHTRKGVAESFIEDVKREVAVIMKNPDEEVKGKMAMYGTSANLPDRTVVGDFARIFLD 534

[80][TOP]
>UniRef100_A8N7P6 Putative uncharacterized protein n=1 Tax=Coprinopsis cinerea
           okayama7#130 RepID=A8N7P6_COPC7
          Length = 569

 Score = 85.9 bits (211), Expect = 1e-15
 Identities = 50/114 (43%), Positives = 66/114 (57%), Gaps = 5/114 (4%)
 Frame = +2

Query: 29  IAELFVVGRPDMTIVAFGSDV--LDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPA 202
           I EL+V+G P  ++VAFGS    +++ EV D MS KGWHLN L  P ++HI VT   VP 
Sbjct: 454 IPELYVLGDPPASVVAFGSKHPNVNVLEVGDAMSKKGWHLNGLSGPPAVHIAVTRLTVPL 513

Query: 203 VDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKM---PDRGMVQELLVDFMD 355
           VD F+ DLK++V   K +P    G +  +YG        PD  MV EL   F+D
Sbjct: 514 VDQFIADLKDAVREAKVSPSG-QGTMVALYGLGNSSAVGPD--MVGELATAFLD 564

[81][TOP]
>UniRef100_B2B105 Predicted CDS Pa_3_7920 n=1 Tax=Podospora anserina
           RepID=B2B105_PODAN
          Length = 570

 Score = 85.5 bits (210), Expect = 2e-15
 Identities = 45/118 (38%), Positives = 69/118 (58%), Gaps = 11/118 (9%)
 Frame = +2

Query: 35  ELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDDF 214
           EL ++G P ++++AF S  L+I+++ D MS+KGWHLNALQ P +IH+ +TL +V   +  
Sbjct: 448 ELEILGNPLVSVIAFKSKTLNIYDIADGMSAKGWHLNALQNPPAIHVALTLPIVKVWEKL 507

Query: 215 LKDLKESVETVKKN-----------PGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
             DL+  VE  K+             G   G  A +YG AG +P++ +V EL   F+D
Sbjct: 508 AADLEAVVEQEKEKERARVAEGKGAKGKEVGDSAALYGVAGSLPNKSVVVELARGFLD 565

[82][TOP]
>UniRef100_A2QJ87 Contig An04c0180, complete genome n=1 Tax=Aspergillus niger CBS
           513.88 RepID=A2QJ87_ASPNC
          Length = 636

 Score = 84.3 bits (207), Expect = 4e-15
 Identities = 48/118 (40%), Positives = 68/118 (57%), Gaps = 12/118 (10%)
 Frame = +2

Query: 38  LFVVGRPDMTIVAFGS--DVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDD 211
           L +VG+P +++VAF S  D +DI+++ D +S+KGWHLNALQ P +IH+  T+    AVD 
Sbjct: 514 LDIVGKPMVSVVAFYSKNDAVDIYDIADSLSAKGWHLNALQSPPAIHVAFTVPTAAAVDA 573

Query: 212 FLKDLKESVET------VKKNPGPI----SGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
              DL  +VE        +K  G       G  A +YG AG MPD+ +V  L   F+D
Sbjct: 574 LTTDLVVAVEAELAKAEERKQQGKSYVVKRGDTAALYGVAGSMPDKSIVSRLAEGFLD 631

[83][TOP]
>UniRef100_C8VL65 Putative uncharacterized protein n=2 Tax=Emericella nidulans
           RepID=C8VL65_EMENI
          Length = 572

 Score = 84.0 bits (206), Expect = 5e-15
 Identities = 50/134 (37%), Positives = 73/134 (54%), Gaps = 16/134 (11%)
 Frame = +2

Query: 2   KSIQKGIEEIAELF----VVGRPDMTIVAFGS--DVLDIFEVNDIMSSKGWHLNALQRPN 163
           K  +  I E A L     VVG+P ++++AF S  D +DI+++ D +S+KGWHLNALQ P 
Sbjct: 434 KKFESAINEDARLSPNLQVVGQPMVSVIAFESKNDAVDIYDIADDLSAKGWHLNALQSPP 493

Query: 164 SIHICVTLQLVPAVDDFLKDLKESVE------TVKKNPGPI----SGGLAPIYGAAGKMP 313
           ++H+  T+    AVD  + DL   VE        +K  G       G  + +YG AG MP
Sbjct: 494 AMHVAFTIPTAAAVDTLISDLVAVVEKELEKAEERKRQGKSYVVKRGDTSALYGVAGSMP 553

Query: 314 DRGMVQELLVDFMD 355
           D+ +V  L   F+D
Sbjct: 554 DKSIVSRLAEGFLD 567

[84][TOP]
>UniRef100_UPI000180C693 PREDICTED: similar to predicted protein n=1 Tax=Ciona intestinalis
           RepID=UPI000180C693
          Length = 543

 Score = 83.6 bits (205), Expect = 6e-15
 Identities = 43/120 (35%), Positives = 67/120 (55%), Gaps = 2/120 (1%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGS--DVLDIFEVNDIMSSKGWHLNALQRPNSIHI 175
           + +++G+  I  L V+G P MT   F +  + L IF + D+M  KGW + A + P+S+H 
Sbjct: 419 EKMKEGVRSIEGLKVLGSPLMTAFGFSTSDESLSIFGIVDVMEEKGWKMEAQRGPDSVHC 478

Query: 176 CVTLQLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
            +    + + D+++ DLK+SVE VKKN      G + IYG    +P  G+V   LVD  D
Sbjct: 479 SILPNHIKSCDEWVSDLKQSVEQVKKNGTNPKNGTSAIYGMLSMVPSDGIVDNFLVDLFD 538

[85][TOP]
>UniRef100_B8C894 Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335
           RepID=B8C894_THAPS
          Length = 203

 Score = 83.6 bits (205), Expect = 6e-15
 Identities = 47/121 (38%), Positives = 73/121 (60%), Gaps = 3/121 (2%)
 Frame = +2

Query: 2   KSIQKGIEE-IAELFVVGRPDMTIVAFGSDV--LDIFEVNDIMSSKGWHLNALQRPNSIH 172
           ++I++GI + I  L V+G P  ++VAF S V  L+I+ +   M+ KGW+LN+LQ P+ +H
Sbjct: 78  RAIKRGIRDGIDGLEVIGDPLSSVVAFRSTVPTLNIYGIGQAMTHKGWNLNSLQYPSCLH 137

Query: 173 ICVTLQLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFM 352
           IC T         FL DL+++V  VK +P   S G A IYG A  +PD  +++ +   F+
Sbjct: 138 ICCTNLHRGKDKQFLNDLRDAVHEVKSHPSKYSQGTAAIYGMAHSLPDSTLLEPIARGFV 197

Query: 353 D 355
           D
Sbjct: 198 D 198

[86][TOP]
>UniRef100_Q7PY31 AGAP001724-PA n=1 Tax=Anopheles gambiae RepID=Q7PY31_ANOGA
          Length = 519

 Score = 83.6 bits (205), Expect = 6e-15
 Identities = 44/119 (36%), Positives = 70/119 (58%), Gaps = 3/119 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           I++ +  I  +F+ G P  +++  GS   DIF +   +S+ GW+LN+LQ P+ IHICVT 
Sbjct: 389 IEQELRAIKNIFIFGTPATSVIGIGSRDFDIFLLGGELSNLGWNLNSLQFPSGIHICVTY 448

Query: 188 QLVPA--VDDFLKDLKESVETVKKNP-GPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
               A   D F++D++  V  + KNP  P+ G +A IYG A  +PDR ++ +    F+D
Sbjct: 449 MHTEAGVADKFIQDVRSKVALIMKNPTKPVEGKMA-IYGVAQSVPDRELIGDFTKCFID 506

[87][TOP]
>UniRef100_Q4JSA1 Sply, Sphingosine-phosphate lyase n=1 Tax=Anopheles gambiae
           RepID=Q4JSA1_ANOGA
          Length = 519

 Score = 83.6 bits (205), Expect = 6e-15
 Identities = 44/119 (36%), Positives = 70/119 (58%), Gaps = 3/119 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           I++ +  I  +F+ G P  +++  GS   DIF +   +S+ GW+LN+LQ P+ IHICVT 
Sbjct: 389 IEQELRAIKNIFIFGTPATSVIGIGSRDFDIFLLGGELSNLGWNLNSLQFPSGIHICVTY 448

Query: 188 QLVPA--VDDFLKDLKESVETVKKNP-GPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
               A   D F++D++  V  + KNP  P+ G +A IYG A  +PDR ++ +    F+D
Sbjct: 449 MHTEAGVADKFIQDVRSKVALIMKNPTKPVEGKMA-IYGVAQSVPDRELIGDFTKCFID 506

[88][TOP]
>UniRef100_C8Z5K6 Dpl1p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z5K6_YEAST
          Length = 589

 Score = 83.6 bits (205), Expect = 6e-15
 Identities = 40/113 (35%), Positives = 67/113 (59%), Gaps = 2/113 (1%)
 Frame = +2

Query: 23  EEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPA 202
           E I +L ++G P  ++++F S  L+I E++D +S KGWH NALQ+P ++H+  T      
Sbjct: 463 ENIPDLNIMGNPRYSVISFSSKTLNIHELSDRLSKKGWHFNALQKPVALHMAFTRLSAHV 522

Query: 203 VDDFLKDLKESVETVK--KNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           VD+    L+ +V+ +K   N  P   G + +YG AG +   G+  +L+V F+D
Sbjct: 523 VDEICDILRTTVQELKSESNSKPSPDGTSALYGVAGSVKTAGVADKLIVGFLD 575

[89][TOP]
>UniRef100_C7YZN5 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
           RepID=C7YZN5_NECH7
          Length = 571

 Score = 83.6 bits (205), Expect = 6e-15
 Identities = 41/118 (34%), Positives = 70/118 (59%), Gaps = 11/118 (9%)
 Frame = +2

Query: 35  ELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDDF 214
           EL ++G+P +++VAF +  L+++++ D MS+KGWHLNALQ P +IH+ VTL +    +  
Sbjct: 449 ELEILGKPLVSVVAFTARNLNVYDIADGMSAKGWHLNALQNPPAIHVAVTLPITKVWEKL 508

Query: 215 LKDLKESVETVKKNP-----------GPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           + DL+  VE  ++             G   G  + +YG AG +P++ +V +L   F+D
Sbjct: 509 IADLEAVVEEEREKERVRIVEGKTAHGKAMGDTSALYGVAGSLPNKSVVVDLATGFLD 566

[90][TOP]
>UniRef100_B5VGH2 YDR294Cp-like protein n=1 Tax=Saccharomyces cerevisiae AWRI1631
           RepID=B5VGH2_YEAS6
          Length = 457

 Score = 83.6 bits (205), Expect = 6e-15
 Identities = 40/113 (35%), Positives = 67/113 (59%), Gaps = 2/113 (1%)
 Frame = +2

Query: 23  EEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPA 202
           E I +L ++G P  ++++F S  L+I E++D +S KGWH NALQ+P ++H+  T      
Sbjct: 331 ENIPDLNIMGNPRYSVISFSSKTLNIHELSDRLSKKGWHFNALQKPVALHMAFTRLSAHV 390

Query: 203 VDDFLKDLKESVETVK--KNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           VD+    L+ +V+ +K   N  P   G + +YG AG +   G+  +L+V F+D
Sbjct: 391 VDEICDILRTTVQELKSESNSKPSPDGTSALYGVAGSVKTAGVADKLIVGFLD 443

[91][TOP]
>UniRef100_B3LG01 Dihydrosphingosine phosphate lyase n=1 Tax=Saccharomyces cerevisiae
           RM11-1a RepID=B3LG01_YEAS1
          Length = 589

 Score = 83.6 bits (205), Expect = 6e-15
 Identities = 40/113 (35%), Positives = 67/113 (59%), Gaps = 2/113 (1%)
 Frame = +2

Query: 23  EEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPA 202
           E I +L ++G P  ++++F S  L+I E++D +S KGWH NALQ+P ++H+  T      
Sbjct: 463 ENIPDLNIMGNPRYSVISFSSKTLNIHELSDRLSKKGWHFNALQKPVALHMAFTRLSAHV 522

Query: 203 VDDFLKDLKESVETVK--KNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           VD+    L+ +V+ +K   N  P   G + +YG AG +   G+  +L+V F+D
Sbjct: 523 VDEICDILRTTVQELKSESNSKPSPDGTSALYGVAGSVKTAGVADKLIVGFLD 575

[92][TOP]
>UniRef100_A6ZYP2 Dihydrosphingosine phosphate lyase n=1 Tax=Saccharomyces cerevisiae
           YJM789 RepID=A6ZYP2_YEAS7
          Length = 589

 Score = 83.6 bits (205), Expect = 6e-15
 Identities = 40/113 (35%), Positives = 67/113 (59%), Gaps = 2/113 (1%)
 Frame = +2

Query: 23  EEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPA 202
           E I +L ++G P  ++++F S  L+I E++D +S KGWH NALQ+P ++H+  T      
Sbjct: 463 ENIPDLNIMGNPRYSVISFSSKTLNIHELSDRLSKKGWHFNALQKPVALHMAFTRLSAHV 522

Query: 203 VDDFLKDLKESVETVK--KNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           VD+    L+ +V+ +K   N  P   G + +YG AG +   G+  +L+V F+D
Sbjct: 523 VDEICDILRTTVQELKSESNSKPSPDGTSALYGVAGSVKTAGVADKLIVGFLD 575

[93][TOP]
>UniRef100_Q05567 Sphingosine-1-phosphate lyase n=2 Tax=Saccharomyces cerevisiae
           RepID=SGPL_YEAST
          Length = 589

 Score = 83.6 bits (205), Expect = 6e-15
 Identities = 40/113 (35%), Positives = 67/113 (59%), Gaps = 2/113 (1%)
 Frame = +2

Query: 23  EEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPA 202
           E I +L ++G P  ++++F S  L+I E++D +S KGWH NALQ+P ++H+  T      
Sbjct: 463 ENIPDLNIMGNPRYSVISFSSKTLNIHELSDRLSKKGWHFNALQKPVALHMAFTRLSAHV 522

Query: 203 VDDFLKDLKESVETVK--KNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           VD+    L+ +V+ +K   N  P   G + +YG AG +   G+  +L+V F+D
Sbjct: 523 VDEICDILRTTVQELKSESNSKPSPDGTSALYGVAGSVKTAGVADKLIVGFLD 575

[94][TOP]
>UniRef100_UPI0000D555CD PREDICTED: similar to sphingosine phosphate lyase isoform 1 n=1
           Tax=Tribolium castaneum RepID=UPI0000D555CD
          Length = 543

 Score = 83.2 bits (204), Expect = 8e-15
 Identities = 43/119 (36%), Positives = 69/119 (57%), Gaps = 3/119 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           I+KG+  +  +F+ G+P  +++A GS+   I+ +   ++  GW+LN LQ P+ IHICVT 
Sbjct: 417 IEKGLRRMKGIFIFGQPATSVIALGSNDFHIYRLGSALNKLGWNLNVLQFPSGIHICVTH 476

Query: 188 QLVP--AVDDFLKDLKESVETVKKNPG-PISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
                   D FL D++ S+  + K P  P+ G +A IYG A  +PDR +V +    F+D
Sbjct: 477 MHTQQGVADKFLNDVQNSLAEILKEPDVPVEGKMA-IYGVAQSVPDRSIVTDFTRLFLD 534

[95][TOP]
>UniRef100_A0DUU2 Chromosome undetermined scaffold_65, whole genome shotgun sequence
           n=1 Tax=Paramecium tetraurelia RepID=A0DUU2_PARTE
          Length = 546

 Score = 83.2 bits (204), Expect = 8e-15
 Identities = 42/119 (35%), Positives = 69/119 (57%), Gaps = 3/119 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDV-LDIFEVNDIMSSKGWHLNALQRPNSIHICVT 184
           + K I EI EL V G+P +  V F S   ++++ ++ I++SKGW+LN  Q PN IHI VT
Sbjct: 423 LAKQINEIPELEVCGQPRINCVCFKSKGNINVYSIHQILTSKGWNLNTTQNPNGIHISVT 482

Query: 185 LQLVPAVDDFLKDLKESVETVKKNPGPI--SGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
            Q +  +  F++++KE+++ +K NP      G +  +YG   K+PD       L  ++D
Sbjct: 483 QQNIQNLKQFVQEIKEAIQEIKANPSQYKKGGDMGALYGTTQKIPDSKFAGNALKLYLD 541

[96][TOP]
>UniRef100_UPI0001792440 PREDICTED: similar to Sphingosine-1-phosphate lyase CG8946-PA n=1
           Tax=Acyrthosiphon pisum RepID=UPI0001792440
          Length = 552

 Score = 82.8 bits (203), Expect = 1e-14
 Identities = 40/118 (33%), Positives = 72/118 (61%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           I++ +  +  +F+ G+P  +++A GSD  +I+ ++D ++S+GW+LN LQ P  IHIC+T 
Sbjct: 428 IEEQLRSMKGIFIFGKPTTSVIAIGSDDFNIYRLSDALNSRGWNLNTLQFPIGIHICITH 487

Query: 185 LQLVPAVDD-FLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           L   P V   F++DL++ +  + K P     G   +YG +  +PDR +V ++   F+D
Sbjct: 488 LHTKPGVASLFIEDLRQELIEILKTPNVELTGKMAMYGMSATLPDRTIVGDITRYFID 545

[97][TOP]
>UniRef100_Q01EF2 Putative sphingosine-1-phosphate lyase (ISS) n=1 Tax=Ostreococcus
           tauri RepID=Q01EF2_OSTTA
          Length = 498

 Score = 82.8 bits (203), Expect = 1e-14
 Identities = 46/122 (37%), Positives = 73/122 (59%), Gaps = 4/122 (3%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDV-LDIFEVNDIMSSKGWHLNALQRPNSIHIC 178
           K +++ I     L ++G     IVA+ +    +I+ +NDI++SKGW L  LQ P ++H C
Sbjct: 375 KKLREAIAATEGLELIGTHITMIVAWHTSTGSNIYVLNDILTSKGWRLAVLQNPKALHFC 434

Query: 179 VTLQLVPAVDDFLKDLKESV---ETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDF 349
           +T   + A+D+ + DL+ +V   +T+K  P    GG APIYG A  +PDRG+++ LL D 
Sbjct: 435 ITPANLSAIDELITDLRSAVRLSQTLKTVP----GGKAPIYGLAHGLPDRGVIKALLKDV 490

Query: 350 MD 355
            D
Sbjct: 491 QD 492

[98][TOP]
>UniRef100_Q2UJL4 Glutamate decarboxylase/sphingosine phosphate lyase n=1
           Tax=Aspergillus oryzae RepID=Q2UJL4_ASPOR
          Length = 572

 Score = 82.8 bits (203), Expect = 1e-14
 Identities = 48/118 (40%), Positives = 67/118 (56%), Gaps = 12/118 (10%)
 Frame = +2

Query: 38  LFVVGRPDMTIVAFGSD--VLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDD 211
           L VVG+P +++VAF S    +DI+++ D +S+KGWHLNALQ P +IH+  T+    A+D 
Sbjct: 450 LDVVGKPMISVVAFQSKNGAVDIYDMADALSAKGWHLNALQSPAAIHVAFTIPTASALDK 509

Query: 212 FLKDLKESVE------TVKKNPGPI----SGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
              DL E VE        +K  G       G  A +YG AG MPD+ +V  L   F+D
Sbjct: 510 LTADLVEVVEKELDKAEERKRQGKSYIIKRGDTAALYGVAGSMPDKSIVSRLAEGFLD 567

[99][TOP]
>UniRef100_B8N0W9 Sphinganine-1-phosphate aldolase BST1, putative n=1 Tax=Aspergillus
           flavus NRRL3357 RepID=B8N0W9_ASPFN
          Length = 438

 Score = 82.8 bits (203), Expect = 1e-14
 Identities = 48/118 (40%), Positives = 67/118 (56%), Gaps = 12/118 (10%)
 Frame = +2

Query: 38  LFVVGRPDMTIVAFGSD--VLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDD 211
           L VVG+P +++VAF S    +DI+++ D +S+KGWHLNALQ P +IH+  T+    A+D 
Sbjct: 316 LDVVGKPMISVVAFQSKNGAVDIYDMADALSAKGWHLNALQSPAAIHVAFTIPTASALDK 375

Query: 212 FLKDLKESVE------TVKKNPGPI----SGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
              DL E VE        +K  G       G  A +YG AG MPD+ +V  L   F+D
Sbjct: 376 LTADLVEVVEKELDKAEERKRQGKSYIIKRGDTAALYGVAGSMPDKSIVSRLAEGFLD 433

[100][TOP]
>UniRef100_B0D1E7 Predicted protein n=1 Tax=Laccaria bicolor S238N-H82
           RepID=B0D1E7_LACBS
          Length = 564

 Score = 82.8 bits (203), Expect = 1e-14
 Identities = 48/116 (41%), Positives = 67/116 (57%), Gaps = 5/116 (4%)
 Frame = +2

Query: 23  EEIAELFVVGRPDMTIVAFGSDV--LDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLV 196
           E I EL+V+G P  ++VAFGS    +++ EV D MS +GWHLN L  P ++HI  T   +
Sbjct: 447 ETIPELYVLGDPPASVVAFGSKHPNVNVLEVGDAMSLRGWHLNGLSDPPAVHIACTRLTL 506

Query: 197 PAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKM---PDRGMVQELLVDFMD 355
           P VD F+ DLK++V   K +P   SG +  +YG        PD  MV +L   F+D
Sbjct: 507 PVVDAFIADLKDAVREAKVSPSG-SGTMVAVYGLGNSSAVGPD--MVGQLATAFLD 559

[101][TOP]
>UniRef100_Q2GNQ0 Putative uncharacterized protein n=1 Tax=Chaetomium globosum
           RepID=Q2GNQ0_CHAGB
          Length = 570

 Score = 82.4 bits (202), Expect = 1e-14
 Identities = 45/120 (37%), Positives = 71/120 (59%), Gaps = 13/120 (10%)
 Frame = +2

Query: 35  ELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDDF 214
           EL ++G P +++VAF +  L+I++V D MS++GWHLNALQ P +IH+ VTL +V   +  
Sbjct: 446 ELEILGNPLVSVVAFRARSLNIYDVADAMSARGWHLNALQDPPAIHVAVTLPIVKVWERL 505

Query: 215 LKDLKESVETV-----------KKNPG--PISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
             DL+  V+             KK  G   ++G  A +YG AG +P++ +V +L   F+D
Sbjct: 506 AADLEAVVDAEREKERARQVEGKKTRGGEAVTGDAAALYGVAGSLPNKSVVVDLASGFLD 565

[102][TOP]
>UniRef100_UPI000051A46E PREDICTED: similar to Sphingosine-1-phosphate lyase CG8946-PA,
           isoform A n=1 Tax=Apis mellifera RepID=UPI000051A46E
          Length = 549

 Score = 82.0 bits (201), Expect = 2e-14
 Identities = 41/119 (34%), Positives = 73/119 (61%), Gaps = 3/119 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           I++ + ++  +F+ G P  +++A GS+   I+++++ +++KGW+LN LQ P  IH+CVT 
Sbjct: 415 IEQRLRKLKGIFIFGTPATSVIALGSNDFHIYKLSEALNAKGWNLNTLQFPCGIHLCVTY 474

Query: 188 QLVPA--VDDFLKDLKESVETVKKNP-GPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
               +   D FL D++  +E + KNP  P+ G  A IYG +  +PDR +V +    F+D
Sbjct: 475 VHTQSGVADQFLSDVETELEEILKNPETPVEGKFA-IYGMSQSIPDRSIVGDFAKCFLD 532

[103][TOP]
>UniRef100_Q17G38 Sphingosine phosphate lyase n=1 Tax=Aedes aegypti
           RepID=Q17G38_AEDAE
          Length = 538

 Score = 82.0 bits (201), Expect = 2e-14
 Identities = 45/119 (37%), Positives = 70/119 (58%), Gaps = 3/119 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           I+  + ++  ++V G P  ++VA GS   DIF ++  ++S GW+LN+LQ P+ IHICVT 
Sbjct: 412 IEAQLRKVDSIYVFGTPATSVVAIGSKDFDIFRLSAELNSLGWNLNSLQFPSGIHICVTY 471

Query: 188 QLVP--AVDDFLKDLKESVETVKKNP-GPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
                   D F+ D++  V  V KNP  P+ G +A IYG A  +PDR ++ +    F+D
Sbjct: 472 MHTQDGIADKFVNDVRTKVALVMKNPEKPVEGKMA-IYGVAQAVPDREVIGDFTKCFID 529

[104][TOP]
>UniRef100_A9UYY0 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9UYY0_MONBE
          Length = 574

 Score = 82.0 bits (201), Expect = 2e-14
 Identities = 44/123 (35%), Positives = 74/123 (60%), Gaps = 3/123 (2%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEV-NDIMSSKGWHLNALQRPNSIHIC 178
           + I +GI++I  L ++  PD  +V++ SDV D++ + + ++   GW LN LQ P SIHIC
Sbjct: 447 REIAEGIKKIPGLRLMCEPDGPVVSWTSDVFDVYRMTHGLIEEHGWDLNVLQFPPSIHIC 506

Query: 179 VTLQLVPA--VDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFM 352
           VTL       V+ FL D+ +    +  NPG  + G A +YG A  +PDR ++++++  ++
Sbjct: 507 VTLAHTREGIVESFLNDMAKVAAPLFANPGVKAEGGAAVYGMAQSIPDRTIIEDVVKTYL 566

Query: 353 DGT 361
           D T
Sbjct: 567 DTT 569

[105][TOP]
>UniRef100_C5PGG5 Sphingosine-1-phosphate lyase, putative n=1 Tax=Coccidioides
           posadasii C735 delta SOWgp RepID=C5PGG5_COCP7
          Length = 565

 Score = 81.3 bits (199), Expect = 3e-14
 Identities = 43/119 (36%), Positives = 65/119 (54%), Gaps = 12/119 (10%)
 Frame = +2

Query: 35  ELFVVGRPDMTIVAFGSDV--LDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVD 208
           +L V+G P +++VAF +    +DI+++ D MS+KGWHLNALQ P ++H+  T+    AVD
Sbjct: 442 DLKVIGEPMVSVVAFATTTAEIDIYDIADAMSAKGWHLNALQNPAAMHVAFTVPTANAVD 501

Query: 209 DFLKDLKESVETVKKNPGPIS----------GGLAPIYGAAGKMPDRGMVQELLVDFMD 355
               DL E VE  +                 G  + +YG AG +PD+ +V  L   F+D
Sbjct: 502 QLTADLTEVVEIKRAKADERKRLGQKVEKERGDTSALYGVAGSIPDKSIVSRLAEGFLD 560

[106][TOP]
>UniRef100_C4JRQ4 Sphingosine-1-phosphate lyase n=1 Tax=Uncinocarpus reesii 1704
           RepID=C4JRQ4_UNCRE
          Length = 571

 Score = 81.3 bits (199), Expect = 3e-14
 Identities = 47/123 (38%), Positives = 67/123 (54%), Gaps = 16/123 (13%)
 Frame = +2

Query: 35  ELFVVGRPDMTIVAFGSDV--LDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVD 208
           +L VVG P +++VAF +    +DI+++ D MS+KGWHLNALQ P ++H+  T+    AVD
Sbjct: 448 DLKVVGEPMVSVVAFAATTAEIDIYDIADAMSAKGWHLNALQNPPAMHVAFTIPTANAVD 507

Query: 209 DFLKDLKESVE--------------TVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVD 346
               DL E VE               V+K  G  S     +YG AG +PD+ +V  L   
Sbjct: 508 KLTTDLVEVVELERAKADERRRLGQKVEKERGDTSA----LYGVAGSIPDKSIVSRLAEG 563

Query: 347 FMD 355
           F+D
Sbjct: 564 FLD 566

[107][TOP]
>UniRef100_B0Y6N4 Sphinganine-1-phosphate aldolase BST1, putative n=2 Tax=Aspergillus
           fumigatus RepID=B0Y6N4_ASPFC
          Length = 572

 Score = 81.3 bits (199), Expect = 3e-14
 Identities = 46/118 (38%), Positives = 68/118 (57%), Gaps = 12/118 (10%)
 Frame = +2

Query: 38  LFVVGRPDMTIVAFGSD--VLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDD 211
           L +VG+P +++VAF S    +DI++V D +S+KGWHLNALQ P +IH+  T+    AV+ 
Sbjct: 450 LGIVGKPMVSVVAFQSQNGAVDIYDVADGLSAKGWHLNALQSPPAIHVAFTIPTAAAVEK 509

Query: 212 FLKDLKESVE------TVKKNPGPI----SGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
              DL E+VE        +K  G       G  + +YG AG +PD+ +V  L   F+D
Sbjct: 510 LTTDLVETVEKELEKAEERKRQGKSYVLKRGDTSALYGVAGSLPDKSIVSRLAEGFLD 567

[108][TOP]
>UniRef100_A1CWS0 Sphinganine-1-phosphate aldolase BST1, putative n=1 Tax=Neosartorya
           fischeri NRRL 181 RepID=A1CWS0_NEOFI
          Length = 572

 Score = 81.3 bits (199), Expect = 3e-14
 Identities = 50/134 (37%), Positives = 72/134 (53%), Gaps = 16/134 (11%)
 Frame = +2

Query: 2   KSIQKGIEE----IAELFVVGRPDMTIVAFGSD--VLDIFEVNDIMSSKGWHLNALQRPN 163
           K  +  IEE       L +VG+P +++VAF S    +DI++V D +S KGWHLNALQ P 
Sbjct: 434 KKFEASIEEHPVLSKNLGIVGKPMVSVVAFQSQNGAVDIYDVADGLSGKGWHLNALQSPP 493

Query: 164 SIHICVTLQLVPAVDDFLKDLKESVE------TVKKNPGPI----SGGLAPIYGAAGKMP 313
           +IH+  T+    AV+    DL E+VE        +K  G       G  + +YG AG +P
Sbjct: 494 AIHVAFTIPTAAAVEKLTTDLVETVEKELEKAEERKRQGKSYVLKRGDTSALYGVAGSIP 553

Query: 314 DRGMVQELLVDFMD 355
           D+ +V  L   F+D
Sbjct: 554 DKSIVSRLAEGFLD 567

[109][TOP]
>UniRef100_UPI000023DDAA hypothetical protein FG04413.1 n=1 Tax=Gibberella zeae PH-1
           RepID=UPI000023DDAA
          Length = 572

 Score = 80.9 bits (198), Expect = 4e-14
 Identities = 43/118 (36%), Positives = 69/118 (58%), Gaps = 11/118 (9%)
 Frame = +2

Query: 35  ELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDDF 214
           EL ++G+P +++VAF +  L+++++ D M +KGWHLNALQ P +IH+ VTL +    +  
Sbjct: 450 ELEIMGKPLVSVVAFTARNLNVYDIADGMGTKGWHLNALQSPPAIHVAVTLPITKVWEKL 509

Query: 215 LKDL---------KESVETV--KKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           + DL         KE V  V  K   G   G  + +YG AG +P++ +V +L   F+D
Sbjct: 510 ITDLEAVVEEEREKERVRLVEGKGTHGKAMGDASALYGVAGSLPNKSVVVDLASGFLD 567

[110][TOP]
>UniRef100_Q1E7L0 Putative uncharacterized protein n=1 Tax=Coccidioides immitis
           RepID=Q1E7L0_COCIM
          Length = 572

 Score = 80.9 bits (198), Expect = 4e-14
 Identities = 43/119 (36%), Positives = 65/119 (54%), Gaps = 12/119 (10%)
 Frame = +2

Query: 35  ELFVVGRPDMTIVAFGSDV--LDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVD 208
           +L V+G P +++VAF +    +DI+++ D MS+KGWHLNALQ P ++H+  T+    AVD
Sbjct: 449 DLKVIGEPMVSVVAFATTTAEIDIYDIADAMSAKGWHLNALQNPAAMHVAFTVPTANAVD 508

Query: 209 DFLKDLKESVETVKKNPGPIS----------GGLAPIYGAAGKMPDRGMVQELLVDFMD 355
               DL E VE  +                 G  + +YG AG +PD+ +V  L   F+D
Sbjct: 509 HLTADLTEVVEIERAKADERKRLGQKVEKERGDTSALYGVAGSIPDKSIVSRLAEGFLD 567

[111][TOP]
>UniRef100_C1UZK8 PLP-dependent enzyme, glutamate decarboxylase n=1 Tax=Haliangium
           ochraceum DSM 14365 RepID=C1UZK8_9DELT
          Length = 514

 Score = 80.5 bits (197), Expect = 5e-14
 Identities = 47/120 (39%), Positives = 73/120 (60%), Gaps = 4/120 (3%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGS--DVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           I+ G+  +  + ++G P + ++AF +  + +DI+ V   MS +GW LN L RP  +H+CV
Sbjct: 392 IKTGLRALPAIEILGDP-LWVIAFAARDERVDIYRVMARMSQRGWSLNGLHRPACVHLCV 450

Query: 182 TLQ-LVPAV-DDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           TL+   P V + F+ DL E++  V+  PG   G  AP+YG A  +P RGMV E+L  +MD
Sbjct: 451 TLRHAEPGVAERFVADLGEAIAEVEAAPGEAEGA-APVYGMAATIPVRGMVGEMLRRYMD 509

[112][TOP]
>UniRef100_A1CHZ0 Sphinganine-1-phosphate aldolase BST1, putative n=1 Tax=Aspergillus
           clavatus RepID=A1CHZ0_ASPCL
          Length = 572

 Score = 80.5 bits (197), Expect = 5e-14
 Identities = 45/118 (38%), Positives = 68/118 (57%), Gaps = 12/118 (10%)
 Frame = +2

Query: 38  LFVVGRPDMTIVAFGSD--VLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDD 211
           L VVG+P +++VAF S    +DI++V D +S+KGWHLNALQ P +IH+  T+    AV+ 
Sbjct: 450 LTVVGKPMVSVVAFQSQNGAIDIYDVADGLSAKGWHLNALQSPPAIHVAFTIPTAAAVEK 509

Query: 212 FLKDLKESVE------TVKKNPGPI----SGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
              DL ++VE        ++  G       G  + +YG AG +PD+ +V  L   F+D
Sbjct: 510 LTSDLVDTVEKELEKAEERRRQGKAYVLKRGDTSALYGVAGSIPDKSIVNRLAEGFLD 567

[113][TOP]
>UniRef100_Q5BZ75 SJCHGC05403 protein (Fragment) n=1 Tax=Schistosoma japonicum
           RepID=Q5BZ75_SCHJA
          Length = 207

 Score = 79.3 bits (194), Expect = 1e-13
 Identities = 42/118 (35%), Positives = 73/118 (61%), Gaps = 6/118 (5%)
 Frame = +2

Query: 20  IEEIAELFVVGRPDMTIVAFGSDVLDIFEVN----DIMSSKGWHLNALQRPNSIHICVTL 187
           + +I  + ++G+P+++IVAFGS+  +I+++     D  + +GW+LN LQ P +IH CVT 
Sbjct: 81  LRKIPGINILGQPNVSIVAFGSNNFNIYKLGHALLDKPNGRGWNLNNLQFPPAIHFCVTD 140

Query: 188 Q--LVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
              +    D F+ D+KE+V+ + K P     G A +YG +  +PDR +V+EL   ++D
Sbjct: 141 MHTVKGCADKFIHDVKEAVKELMKTPNTKPEGSAALYGLSHMIPDRSIVEELAHCYLD 198

[114][TOP]
>UniRef100_Q0CZH7 Putative uncharacterized protein n=1 Tax=Aspergillus terreus
           NIH2624 RepID=Q0CZH7_ASPTN
          Length = 572

 Score = 79.3 bits (194), Expect = 1e-13
 Identities = 48/118 (40%), Positives = 66/118 (55%), Gaps = 12/118 (10%)
 Frame = +2

Query: 38  LFVVGRPDMTIVAFGSDV--LDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDD 211
           L VVG+P +++VAF S    +D +++ D +S+KGWHLNALQ P +IH+  TL    AVD 
Sbjct: 450 LGVVGKPMVSVVAFESTNPGVDTYDLADGLSAKGWHLNALQSPPAIHVAFTLPTAAAVDK 509

Query: 212 FLKDLKESVE------TVKKNPGPI----SGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
              DL E +E        +K  G       G  A +YG AG MPD+ +V  L   F+D
Sbjct: 510 LTADLVEVLEKELAKAEERKRQGKSYVIKRGDTAALYGVAGSMPDKSVVSRLAEGFLD 567

[115][TOP]
>UniRef100_C6H2K0 Sphingosine-1-phosphate lyase n=1 Tax=Ajellomyces capsulatus H143
           RepID=C6H2K0_AJECH
          Length = 573

 Score = 79.3 bits (194), Expect = 1e-13
 Identities = 42/118 (35%), Positives = 66/118 (55%), Gaps = 12/118 (10%)
 Frame = +2

Query: 38  LFVVGRPDMTIVAFGSDV--LDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDD 211
           L V+G+P +++VA+ S    +DI+++ D +S+KGWHLNALQ P +IH+  T+    AV+ 
Sbjct: 451 LAVIGKPSVSVVAWQSATPEIDIYDIADALSAKGWHLNALQTPPAIHVAFTVPTAAAVEK 510

Query: 212 FLKDLKESVETVKKNPGPIS----------GGLAPIYGAAGKMPDRGMVQELLVDFMD 355
            + DL   VE  K                 G ++ +YG AG +PD+ +V  L   F+D
Sbjct: 511 LIADLVAVVEQEKAKVAERKKLGLKVEKERGDVSALYGVAGSIPDKSIVSRLAEGFLD 568

[116][TOP]
>UniRef100_UPI00015B42F4 PREDICTED: similar to sphingosine phosphate lyase n=1 Tax=Nasonia
           vitripennis RepID=UPI00015B42F4
          Length = 567

 Score = 79.0 bits (193), Expect = 2e-13
 Identities = 37/118 (31%), Positives = 73/118 (61%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           I++ +  +  ++V G P  +++A GS   +I+ ++  ++++GW+LN LQ P++IHICVT 
Sbjct: 419 IERELRGMNNIYVFGTPMTSVIAVGSHDFEIYRLSQALNARGWNLNTLQFPSAIHICVTH 478

Query: 185 LQLVPAV-DDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           +   P V   F+ D++  +E + + P   + G+  +YG+A  +PDR +V ++   F+D
Sbjct: 479 VHTEPGVAQQFVDDVRFELEKIMQTPKEEAEGIYALYGSAQTIPDRSVVGDITKSFID 536

[117][TOP]
>UniRef100_B0XFI0 Sphingosine-1-phosphate lyase n=1 Tax=Culex quinquefasciatus
           RepID=B0XFI0_CULQU
          Length = 539

 Score = 79.0 bits (193), Expect = 2e-13
 Identities = 44/119 (36%), Positives = 69/119 (57%), Gaps = 3/119 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           I+  + +I  +++ G P  ++VA GS   DIF ++  ++  GW+LN+LQ P+ IHICVT 
Sbjct: 412 IETELRKIDNIYIFGTPATSVVAIGSKDFDIFRLSGELNGLGWNLNSLQFPSGIHICVTH 471

Query: 188 QLVP--AVDDFLKDLKESVETVKKNP-GPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
                   D F+ D++  V    +NP  P+ G +A IYG A ++PDR +V E    F+D
Sbjct: 472 MHTQNGIADKFVADVRSKVALCMQNPEKPVEGKMA-IYGVAQEVPDREVVGEFTKCFID 529

[118][TOP]
>UniRef100_C5FUQ1 Sphingosine-1-phosphate lyase n=1 Tax=Microsporum canis CBS 113480
           RepID=C5FUQ1_NANOT
          Length = 574

 Score = 79.0 bits (193), Expect = 2e-13
 Identities = 45/118 (38%), Positives = 68/118 (57%), Gaps = 12/118 (10%)
 Frame = +2

Query: 38  LFVVGRPDMTIVAFGSD--VLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDD 211
           L VVGRP +++V F S    +DI++V D MS+ GWHLNALQ P ++H+  TL    AVD 
Sbjct: 452 LEVVGRPMVSVVGFTSTNPEVDIYDVADAMSNMGWHLNALQSPPAMHVAFTLPTANAVDK 511

Query: 212 FLKDL-----KESVETVKKNPGPIS-----GGLAPIYGAAGKMPDRGMVQELLVDFMD 355
            ++DL     +E  +  ++    I      G  + +YG AG +PD+ +V+ L   F+D
Sbjct: 512 LIEDLTTVVQQELTKIAERKAAGIKVEKKRGDTSALYGVAGSIPDKSIVRRLAEGFLD 569

[119][TOP]
>UniRef100_B8LWR8 Sphinganine-1-phosphate aldolase BST1, putative n=1 Tax=Talaromyces
           stipitatus ATCC 10500 RepID=B8LWR8_TALSN
          Length = 574

 Score = 79.0 bits (193), Expect = 2e-13
 Identities = 46/120 (38%), Positives = 67/120 (55%), Gaps = 12/120 (10%)
 Frame = +2

Query: 32  AELFVVGRPDMTIVAFGSDV--LDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAV 205
           A L V+G+P++++VAF S    +D +++ D MS+KGWHLNALQ P +IH+  T     AV
Sbjct: 450 ANLEVIGKPEVSVVAFASKNVGIDTYDIADAMSAKGWHLNALQDPPAIHMAFTRPTALAV 509

Query: 206 DDFLKDLKE--SVETVK--------KNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           +    +L E  S E  K        K+     G  A +YG AG +PD+ +V  L   F+D
Sbjct: 510 EKLQTELTEVVSAELAKAEERQRQGKSYAKQRGDTAALYGVAGSLPDKSIVSRLAEGFLD 569

[120][TOP]
>UniRef100_C1US47 PLP-dependent enzyme, glutamate decarboxylase n=1 Tax=Haliangium
           ochraceum DSM 14365 RepID=C1US47_9DELT
          Length = 513

 Score = 78.6 bits (192), Expect = 2e-13
 Identities = 41/114 (35%), Positives = 66/114 (57%), Gaps = 2/114 (1%)
 Frame = +2

Query: 17  GIEEIAELFVVGRPDMTIVAFGS--DVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQ 190
           GI  I  L + G P M++V FG+    LDIF V D +  +GWH++  Q PNSIH+ +  Q
Sbjct: 345 GIHTIDGLQIFGAPHMSLVCFGARDPELDIFAVADALERRGWHIDRQQSPNSIHVTLMPQ 404

Query: 191 LVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFM 352
            +  ++ +L D+ E+V+ V+ +P   + G A +YG   KMP   + +  +V+ M
Sbjct: 405 HLEVLERYLSDIAEAVDEVRADPSLRTQGQAAMYGMMAKMPFARITRRGVVELM 458

[121][TOP]
>UniRef100_C4QDT2 Sphingosine phosphate lyase, putative n=1 Tax=Schistosoma mansoni
            RepID=C4QDT2_SCHMA
          Length = 1239

 Score = 78.6 bits (192), Expect = 2e-13
 Identities = 41/118 (34%), Positives = 70/118 (59%), Gaps = 6/118 (5%)
 Frame = +2

Query: 20   IEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSK----GWHLNALQRPNSIHICVTL 187
            + +I  +FV G P++++VAF S+  DI++++  +S K    GW+LN LQ P ++H+CVT 
Sbjct: 1114 LRKIPGIFVFGEPNVSVVAFSSNNFDIYKLSHSLSDKPNGRGWNLNNLQFPPAVHLCVTD 1173

Query: 188  QLVP--AVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
                    + F++D+KE  + + K P   S G   +YG +  +PDR +V EL   ++D
Sbjct: 1174 MHTTKGCAERFIQDVKEIAKELMKKPNKKSKGSVALYGLSQMIPDRSIVTELAHCYLD 1231

[122][TOP]
>UniRef100_C0NMW5 Sphingosine-1-phosphate lyase n=1 Tax=Ajellomyces capsulatus G186AR
           RepID=C0NMW5_AJECG
          Length = 573

 Score = 78.6 bits (192), Expect = 2e-13
 Identities = 42/118 (35%), Positives = 65/118 (55%), Gaps = 12/118 (10%)
 Frame = +2

Query: 38  LFVVGRPDMTIVAFGSDV--LDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDD 211
           L V+G+P +++VA+ S    +DI+++ D +S+KGWHLNALQ P +IH+  T+    AV+ 
Sbjct: 451 LAVIGKPSVSVVAWQSATPEIDIYDIADALSAKGWHLNALQTPPAIHVAFTVPTAAAVEK 510

Query: 212 FLKDLKESVETVKKNPGPIS----------GGLAPIYGAAGKMPDRGMVQELLVDFMD 355
            + DL   VE  K                 G  + +YG AG +PD+ +V  L   F+D
Sbjct: 511 LIADLVAVVEQEKAKVAERKKLGLKVEKERGDASALYGVAGSIPDKSIVSRLAEGFLD 568

[123][TOP]
>UniRef100_Q67PY4 Putative sphingosine-1-phosphate lyase n=1 Tax=Symbiobacterium
           thermophilum RepID=Q67PY4_SYMTH
          Length = 507

 Score = 78.2 bits (191), Expect = 3e-13
 Identities = 42/118 (35%), Positives = 73/118 (61%), Gaps = 2/118 (1%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           ++ G+  I  L ++G P + ++A  SD L+I++V + M+ +GW LN L RP + H+ +TL
Sbjct: 388 LKAGVRAIPSLKILGDP-LWVIAVASDELNIYQVMEEMAGRGWRLNGLHRPPAFHVALTL 446

Query: 188 QLVP--AVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           +      VD FL DL+++V  V+ +P   + G+AP+YG A   P   +V+++L  F+D
Sbjct: 447 RHTEPGVVDRFLADLQDAVAQVRAHPEKAT-GMAPVYGMAAAAPPE-LVRQVLTGFID 502

[124][TOP]
>UniRef100_B6HST2 Pc22g13200 protein n=1 Tax=Penicillium chrysogenum Wisconsin
           54-1255 RepID=B6HST2_PENCW
          Length = 572

 Score = 78.2 bits (191), Expect = 3e-13
 Identities = 43/116 (37%), Positives = 64/116 (55%), Gaps = 12/116 (10%)
 Frame = +2

Query: 44  VVGRPDMTIVAFGSD--VLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDDFL 217
           V+G P +++VAF S    +DI+++ D +S+KGWHLNALQ P +IH   T+    AVD  +
Sbjct: 452 VIGNPIVSVVAFRSKNGAIDIYDIADDLSAKGWHLNALQSPAAIHCAFTIPTAKAVDQLI 511

Query: 218 KDLKESV------ETVKKNPGPI----SGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
            DL E +         +K  G       G  + +YG AG +PD+ +V  L   F+D
Sbjct: 512 ADLSEVIGKELEKAEQRKREGKSYILKRGDTSALYGVAGSIPDKSVVSRLAEGFLD 567

[125][TOP]
>UniRef100_A4RHU4 Putative uncharacterized protein n=1 Tax=Magnaporthe grisea
           RepID=A4RHU4_MAGGR
          Length = 567

 Score = 78.2 bits (191), Expect = 3e-13
 Identities = 41/119 (34%), Positives = 65/119 (54%), Gaps = 11/119 (9%)
 Frame = +2

Query: 32  AELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDD 211
           AEL ++G+P  ++VAF +  L+I+++ D M  KGWHLN+LQ P ++H+  TL      + 
Sbjct: 444 AELEIIGKPLSSVVAFRARNLNIYDIADAMGEKGWHLNSLQNPPAMHVAFTLPTAKVWER 503

Query: 212 FLKDLKESVETVKKN-----------PGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
              DL+  VE  ++             G   G  A +YG AG +P++ +V EL   F+D
Sbjct: 504 LATDLEACVEGEREKERARIAEGKGAKGAAVGDSAALYGVAGSLPNKSVVVELANGFLD 562

[126][TOP]
>UniRef100_C5GFQ5 Sphinganine-1-phosphate aldolase BST1 n=1 Tax=Ajellomyces
           dermatitidis ER-3 RepID=C5GFQ5_AJEDR
          Length = 573

 Score = 77.4 bits (189), Expect = 4e-13
 Identities = 42/118 (35%), Positives = 66/118 (55%), Gaps = 12/118 (10%)
 Frame = +2

Query: 38  LFVVGRPDMTIVAFGSDV--LDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDD 211
           L V+G+P +++VA+ S    +DI+++ D +S+KGWHLNALQ P +IH+  T+    AV+ 
Sbjct: 451 LKVLGKPMVSVVAWDSATPEIDIYDIADALSAKGWHLNALQAPPAIHVAFTVPTAGAVEK 510

Query: 212 FLKDLKESVETVKKNPGPI----------SGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
            + DL   VE  ++                G  A +YG AG +PD+ +V  L   F+D
Sbjct: 511 LIADLVAVVEQEREKAAERKRLGLKVEKGKGDAAALYGVAGSIPDKSIVSRLAEGFLD 568

[127][TOP]
>UniRef100_B6QPY0 Sphinganine-1-phosphate aldolase BST1, putative n=1 Tax=Penicillium
           marneffei ATCC 18224 RepID=B6QPY0_PENMQ
          Length = 574

 Score = 77.0 bits (188), Expect = 6e-13
 Identities = 45/120 (37%), Positives = 65/120 (54%), Gaps = 12/120 (10%)
 Frame = +2

Query: 32  AELFVVGRPDMTIVAFGSDV--LDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAV 205
           A L V+G P +++VAF S    +D +++ D MS+KGWHLNALQ P +IH+  T     AV
Sbjct: 450 ANLEVIGNPQVSVVAFASKNVGIDTYDIADAMSAKGWHLNALQDPAAIHVAFTRPTALAV 509

Query: 206 DDFLKDLKE--SVETVK--------KNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           +    +L E  S E  K        K+     G  + +YG AG +PD+ +V  L   F+D
Sbjct: 510 EKLQSELTEVVSAELAKAEERQRQGKSYARQRGDTSALYGVAGSLPDKSIVSRLAEGFLD 569

[128][TOP]
>UniRef100_A8PYD7 Putative uncharacterized protein n=1 Tax=Malassezia globosa CBS
           7966 RepID=A8PYD7_MALGO
          Length = 263

 Score = 76.3 bits (186), Expect = 1e-12
 Identities = 48/122 (39%), Positives = 72/122 (59%), Gaps = 4/122 (3%)
 Frame = +2

Query: 2   KSIQKGIE-EIAELFVVGRPDMTIVAFGS-DVLDIFEVNDIMSSKGWHLNALQRP-NSIH 172
           K I+K +  EI EL ++G+P ++++AF S   ++I++V D MS +GWHLNAL     + H
Sbjct: 134 KEIEKRVRAEIPELVILGKPLVSVLAFASAGNVNIYDVGDQMSRRGWHLNALSGDMPAFH 193

Query: 173 ICVTLQLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGM-VQELLVDF 349
           I  T   VP VD F+ DLKESV   +  P   SG +A +YG     P   M ++E+   +
Sbjct: 194 IACTRLTVPVVDRFVHDLKESVAASRSRPSK-SGAMATVYGLHTTTPVAPMLLKEMAARY 252

Query: 350 MD 355
           +D
Sbjct: 253 ID 254

[129][TOP]
>UniRef100_UPI00003BDB49 hypothetical protein DEHA0D17589g n=1 Tax=Debaryomyces hansenii
           CBS767 RepID=UPI00003BDB49
          Length = 596

 Score = 75.1 bits (183), Expect = 2e-12
 Identities = 36/111 (32%), Positives = 60/111 (54%), Gaps = 5/111 (4%)
 Frame = +2

Query: 38  LFVVGRPDMTIVAFG-----SDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPA 202
           L V+G P  ++VAFG        L I+++ + +SSKGWH + LQ P ++H  +T   VP 
Sbjct: 481 LEVIGDPIGSVVAFGVTKNYRSTLSIYKIGECLSSKGWHFSTLQNPAALHFALTRLTVPV 540

Query: 203 VDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           + + + DL E      K+       +A +YG AG +   G+ + ++V F+D
Sbjct: 541 IGELISDLVEVTSAALKDESNSESEIAALYGVAGSVKTTGVAERVVVAFLD 591

[130][TOP]
>UniRef100_Q08TY4 Sphingosine-1-phosphate lyase 1 n=1 Tax=Stigmatella aurantiaca
           DW4/3-1 RepID=Q08TY4_STIAU
          Length = 440

 Score = 75.1 bits (183), Expect = 2e-12
 Identities = 38/114 (33%), Positives = 61/114 (53%)
 Frame = +2

Query: 17  GIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLV 196
           GI  I  L V+G P + + AF SD L+++E+ D M ++GW ++  Q P ++H  +T    
Sbjct: 323 GINAIPGLRVLGAPQVGVFAFSSDSLNVYELGDAMEARGWKMDRQQNPPALHCMITPSHE 382

Query: 197 PAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMDG 358
             V+  L DL++    +     P   G A +YG  G +PD   V   L++F+DG
Sbjct: 383 RIVEPLLADLRDCASKLAAGE-PAPEGSAAMYGMVGAIPDSKQVDGFLLEFLDG 435

[131][TOP]
>UniRef100_A8Q048 Pyridoxal-dependent decarboxylase conserved domain containing
           protein n=1 Tax=Brugia malayi RepID=A8Q048_BRUMA
          Length = 557

 Score = 75.1 bits (183), Expect = 2e-12
 Identities = 41/115 (35%), Positives = 66/115 (57%), Gaps = 3/115 (2%)
 Frame = +2

Query: 20  IEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQ--L 193
           + +I  L ++G PD++IVAF SDV +I+ + D MS+ GW+LN++Q P   HICVT    L
Sbjct: 430 MNDIDGLRLLGSPDISIVAFTSDVFNIYALVDDMSALGWNLNSIQNPAGAHICVTYNTVL 489

Query: 194 VPAVDDFLKDLKESVETVKKNPGPIS-GGLAPIYGAAGKMPDRGMVQELLVDFMD 355
             A   F+ DL++    +  +P       +A IYG    +PD+ ++  L   ++D
Sbjct: 490 ANAWRTFIDDLRKVAFALMNDPDREKYSNMAAIYGLTANIPDKQLISNLAYCYLD 544

[132][TOP]
>UniRef100_Q6BRI1 DEHA2D16192p n=1 Tax=Debaryomyces hansenii RepID=Q6BRI1_DEBHA
          Length = 596

 Score = 75.1 bits (183), Expect = 2e-12
 Identities = 36/111 (32%), Positives = 60/111 (54%), Gaps = 5/111 (4%)
 Frame = +2

Query: 38  LFVVGRPDMTIVAFG-----SDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPA 202
           L V+G P  ++VAFG        L I+++ + +SSKGWH + LQ P ++H  +T   VP 
Sbjct: 481 LEVIGDPIGSVVAFGVTKNYRSTLSIYKIGECLSSKGWHFSTLQNPAALHFALTRLTVPV 540

Query: 203 VDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           + + + DL E      K+       +A +YG AG +   G+ + ++V F+D
Sbjct: 541 IGELISDLVEVTSAALKDESNSESEIAALYGVAGSVKTTGVAERVVVAFLD 591

[133][TOP]
>UniRef100_Q5KCC8 Sphinganine-1-phosphate aldolase, putative n=1 Tax=Filobasidiella
           neoformans RepID=Q5KCC8_CRYNE
          Length = 546

 Score = 74.3 bits (181), Expect = 4e-12
 Identities = 36/107 (33%), Positives = 60/107 (56%)
 Frame = +2

Query: 35  ELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDDF 214
           +L+V+G P   +VAF S  ++I+ V D+MS KGWHL+AL     +H+  T     +VD  
Sbjct: 436 DLYVLGDPKGPVVAFNSKTINIYAVGDVMSKKGWHLSALGGDGGLHMAFTRLSAKSVDKL 495

Query: 215 LKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           ++DL ++++ VK +P    G +  +YG         +V +L   F+D
Sbjct: 496 IEDLGDALKEVKASPQGAGGDMVALYGLGQTSAGPHVVGKLAETFLD 542

[134][TOP]
>UniRef100_Q55JD1 Putative uncharacterized protein n=1 Tax=Filobasidiella neoformans
           RepID=Q55JD1_CRYNE
          Length = 546

 Score = 74.3 bits (181), Expect = 4e-12
 Identities = 36/107 (33%), Positives = 60/107 (56%)
 Frame = +2

Query: 35  ELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDDF 214
           +L+V+G P   +VAF S  ++I+ V D+MS KGWHL+AL     +H+  T     +VD  
Sbjct: 436 DLYVLGDPKGPVVAFNSKTINIYAVGDVMSKKGWHLSALGGDGGLHMAFTRLSAKSVDKL 495

Query: 215 LKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           ++DL ++++ VK +P    G +  +YG         +V +L   F+D
Sbjct: 496 IEDLGDALKEVKASPQGAGGDMVALYGLGQTSAGPHVVGKLAETFLD 542

[135][TOP]
>UniRef100_Q9Y194 Sphingosine-1-phosphate lyase n=1 Tax=Caenorhabditis elegans
           RepID=SGPL_CAEEL
          Length = 552

 Score = 73.2 bits (178), Expect = 8e-12
 Identities = 41/123 (33%), Positives = 73/123 (59%), Gaps = 3/123 (2%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           + + + IE+I  +   G+ D+++VAF  + ++I+EV+D M   GW+LN LQ P +IHIC+
Sbjct: 422 RMLAEKIEKIKWIKPYGKSDVSLVAFSGNGVNIYEVSDKMMKLGWNLNTLQNPAAIHICL 481

Query: 182 TLQLV--PAVDDFLKDLKESVETV-KKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFM 352
           T+       V+ F  DL++  E +  K       G+A +YG A ++P + +V E++  ++
Sbjct: 482 TINQANEEVVNAFAVDLEKICEELAAKGEQKADSGMAAMYGMAAQVP-KSVVDEVIALYI 540

Query: 353 DGT 361
           D T
Sbjct: 541 DAT 543

[136][TOP]
>UniRef100_A0D650 Chromosome undetermined scaffold_39, whole genome shotgun sequence
           n=1 Tax=Paramecium tetraurelia RepID=A0D650_PARTE
          Length = 559

 Score = 72.8 bits (177), Expect = 1e-11
 Identities = 36/122 (29%), Positives = 70/122 (57%), Gaps = 4/122 (3%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDV--LDIFEVNDIMSSKGWHLNALQRPNSIHI 175
           +S+ K + EI E+ V G P +  VAF S    L+ + +++I++ +GW ++++Q P  +HI
Sbjct: 433 QSLAKQLSEIPEIKVFGNPQINCVAFMSKESWLNAYSIHEILTHQGWTISSVQNPAGVHI 492

Query: 176 CVTLQLVPAVDDFLKDLKESVETVKKNPGPI--SGGLAPIYGAAGKMPDRGMVQELLVDF 349
            +T Q +  +  ++ D+K ++E +K NP      G +  +YG   K+PD  +  + L  +
Sbjct: 493 SLTQQNIVNLKQYVHDIKAAIEKIKANPQVYQKGGEMGTLYGTTQKIPDSKLAGQALKVY 552

Query: 350 MD 355
           +D
Sbjct: 553 LD 554

[137][TOP]
>UniRef100_C4R8D3 Dihydrosphingosine phosphate lyase n=1 Tax=Pichia pastoris GS115
           RepID=C4R8D3_PICPG
          Length = 571

 Score = 72.8 bits (177), Expect = 1e-11
 Identities = 38/125 (30%), Positives = 68/125 (54%), Gaps = 7/125 (5%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           + I+  I+ I  L ++G P  ++VAF S+   I+++ D +S+KGWHL+ LQRP +IHI V
Sbjct: 442 RKIKSEIQSIKGLSIIGDPIGSVVAFTSENYSIYDITDRLSAKGWHLSTLQRPPAIHIAV 501

Query: 182 TLQLVPAVDDFLKDLKESVETVKKNPGPISGG-------LAPIYGAAGKMPDRGMVQELL 340
           T+      ++ + DLK  +  ++++      G        A +YG AG +    +   ++
Sbjct: 502 TIPTCKVSNELISDLKNIMTEIERDAEDPKIGKKENKNDTAALYGIAGSVKTGPIADRVI 561

Query: 341 VDFMD 355
             F+D
Sbjct: 562 EAFLD 566

[138][TOP]
>UniRef100_A5DZL7 Sphingosine-1-phosphate lyase n=1 Tax=Lodderomyces elongisporus
           RepID=A5DZL7_LODEL
          Length = 584

 Score = 72.8 bits (177), Expect = 1e-11
 Identities = 41/127 (32%), Positives = 66/127 (51%), Gaps = 9/127 (7%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDV-----LDIFEVNDIMSSKGWHLNALQRPNS 166
           K+I+K       L ++G P  ++V+F         L I+E+ D+++ KGWH   LQ P +
Sbjct: 454 KAIEKDSTLSEYLEIIGNPIGSVVSFKVKTSKKKELSIYELGDLLTKKGWHFATLQNPAA 513

Query: 167 IHICVTLQLVPAVDDFLKDL----KESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQE 334
           +H   T    P VD+ + DL    KE++E  KK  G      A +YG AG +   G+  +
Sbjct: 514 LHFAFTRLTTPVVDELIDDLVGCTKEAIELTKKT-GKKQSDTAALYGIAGSVHTAGLADK 572

Query: 335 LLVDFMD 355
           ++V F+D
Sbjct: 573 IIVAFLD 579

[139][TOP]
>UniRef100_A5DBE5 Putative uncharacterized protein n=1 Tax=Pichia guilliermondii
           RepID=A5DBE5_PICGU
          Length = 588

 Score = 72.8 bits (177), Expect = 1e-11
 Identities = 38/109 (34%), Positives = 63/109 (57%), Gaps = 3/109 (2%)
 Frame = +2

Query: 38  LFVVGRPDMTIVAFGSD--VLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDD 211
           L V+G P  +++AF S    ++I+++ D +++KGWH  ALQ+P ++H   T   VP V++
Sbjct: 475 LEVLGDPIASVIAFKSKNASVNIYDLGDALTAKGWHFAALQKPAALHFAFTRLTVPIVNE 534

Query: 212 FLKDLKESVETVKKN-PGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
            ++DL E  E +  N  G      A IYG AG +   G+   ++V F+D
Sbjct: 535 LIRDLIECTEELAANKSGNKKNDTAAIYGVAGSVSTSGVANRIIVAFLD 583

[140][TOP]
>UniRef100_A8XBE1 C. briggsae CBR-SPL-1 protein n=1 Tax=Caenorhabditis briggsae
           RepID=A8XBE1_CAEBR
          Length = 552

 Score = 72.0 bits (175), Expect = 2e-11
 Identities = 42/118 (35%), Positives = 72/118 (61%), Gaps = 4/118 (3%)
 Frame = +2

Query: 20  IEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLV- 196
           I++I  +   G  D+++VAF  + ++I+EV+D M   GW+LN LQ P +IHIC+T+    
Sbjct: 428 IQKIKWVKPYGSSDVSLVAFSGNGINIYEVSDRMMKLGWNLNTLQNPAAIHICLTINQAN 487

Query: 197 -PAVDDFLKDLKESVETVKK--NPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMDGT 361
              V+ F+ DL+++ E V    N  P   G+A +YG A ++P + +V E++  ++D T
Sbjct: 488 EEVVNAFVSDLQKTCEDVAAAGNQKP-DHGMAAMYGMAAQVP-KSVVDEVIALYIDAT 543

[141][TOP]
>UniRef100_C1G3V6 Sphingosine-1-phosphate lyase n=1 Tax=Paracoccidioides brasiliensis
           Pb18 RepID=C1G3V6_PARBD
          Length = 573

 Score = 70.9 bits (172), Expect = 4e-11
 Identities = 39/120 (32%), Positives = 65/120 (54%), Gaps = 12/120 (10%)
 Frame = +2

Query: 32  AELFVVGRPDMTIVAFGSDVLDI--FEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAV 205
           + L ++G+P +++VA+ S   DI  +++ D ++ KGWHLNALQ P  +H+  T+    AV
Sbjct: 449 SSLKIIGKPLVSVVAWESKTPDINIYDIADALADKGWHLNALQSPPGMHVAFTVPTAAAV 508

Query: 206 DDFLKDL-------KESVETVKKNPGPIS---GGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           +  + DL       KE V   K+    +    G  + +YG AG +PD+ +V      F+D
Sbjct: 509 ERLVADLVAVVEREKEKVAEQKRMGQKVEKHRGDTSALYGVAGSIPDKSIVNRFAEGFLD 568

[142][TOP]
>UniRef100_C0S546 Sphingosine-1-phosphate lyase n=1 Tax=Paracoccidioides brasiliensis
           Pb03 RepID=C0S546_PARBP
          Length = 558

 Score = 70.9 bits (172), Expect = 4e-11
 Identities = 39/120 (32%), Positives = 65/120 (54%), Gaps = 12/120 (10%)
 Frame = +2

Query: 32  AELFVVGRPDMTIVAFGSDVLDI--FEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAV 205
           + L ++G+P +++VA+ S   DI  +++ D ++ KGWHLNALQ P  +H+  T+    AV
Sbjct: 434 SSLKIIGKPLVSVVAWESKTPDINIYDIADALADKGWHLNALQSPPGMHVAFTVPTAAAV 493

Query: 206 DDFLKDL-------KESVETVKKNPGPIS---GGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           +  + DL       KE V   K+    +    G  + +YG AG +PD+ +V      F+D
Sbjct: 494 ERLVADLVAVVEREKEKVAEQKRMGQKVEKHRGDTSALYGVAGSIPDKSIVNRFAEGFLD 553

[143][TOP]
>UniRef100_A6RAW5 Putative uncharacterized protein n=1 Tax=Ajellomyces capsulatus
           NAm1 RepID=A6RAW5_AJECN
          Length = 593

 Score = 70.9 bits (172), Expect = 4e-11
 Identities = 39/109 (35%), Positives = 60/109 (55%), Gaps = 12/109 (11%)
 Frame = +2

Query: 38  LFVVGRPDMTIVAFGSDV--LDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDD 211
           L V+G+P  ++VA+ S    +DI+++ D +S+KGWHLNALQ P +IH+  T+    AV+ 
Sbjct: 451 LAVIGKPMASVVAWQSATPEIDIYDIADALSAKGWHLNALQTPPAIHVAFTVPTAAAVEK 510

Query: 212 FLKDLKESVETVKKNPGPIS----------GGLAPIYGAAGKMPDRGMV 328
            + DL   VE  K                 G  + +YG AG +PD+ +V
Sbjct: 511 LIVDLVAVVEQEKAKVAERKKLGLKVEKERGDASALYGVAGSIPDKSIV 559

[144][TOP]
>UniRef100_A3LPY6 Dihydrosphingosine-1-phosphate lyase n=1 Tax=Pichia stipitis
           RepID=A3LPY6_PICST
          Length = 603

 Score = 70.9 bits (172), Expect = 4e-11
 Identities = 37/115 (32%), Positives = 60/115 (52%), Gaps = 9/115 (7%)
 Frame = +2

Query: 38  LFVVGRPDMTIVAF------GSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVP 199
           L V+G P  ++++F            ++E+ DI+  KGWH + LQ P ++H   T   +P
Sbjct: 484 LEVIGEPVASVISFKVKDEYAKKKFSVYELGDILKKKGWHFSTLQHPPALHFAFTKLTIP 543

Query: 200 AVDDFLKDLKESVETVK---KNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
            VD+ L DL  SV  +    +N    S  +A IYG AG +   G+  +++V F+D
Sbjct: 544 IVDEMLADLVSSVHELVDHWENSTTPSSDVATIYGVAGSVRTAGVADKVIVAFLD 598

[145][TOP]
>UniRef100_UPI000151AD88 hypothetical protein PGUG_00600 n=1 Tax=Pichia guilliermondii ATCC
           6260 RepID=UPI000151AD88
          Length = 588

 Score = 70.5 bits (171), Expect = 5e-11
 Identities = 37/109 (33%), Positives = 62/109 (56%), Gaps = 3/109 (2%)
 Frame = +2

Query: 38  LFVVGRPDMTIVAFG--SDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDD 211
           L V+G P   ++AF   +  ++I+++ D +++KGWH  ALQ+P ++H   T   VP V++
Sbjct: 475 LEVLGDPIALVIAFKLKNASVNIYDLGDALTAKGWHFAALQKPAALHFAFTRLTVPIVNE 534

Query: 212 FLKDLKESVETVKKN-PGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
            ++DL E  E +  N  G      A IYG AG +   G+   ++V F+D
Sbjct: 535 LIRDLIECTEELAANKSGNKKNDTAAIYGVAGSVSTSGVANRIIVAFLD 583

[146][TOP]
>UniRef100_Q2TW35 Glutamate decarboxylase/sphingosine phosphate lyase n=1
           Tax=Aspergillus oryzae RepID=Q2TW35_ASPOR
          Length = 566

 Score = 70.5 bits (171), Expect = 5e-11
 Identities = 38/116 (32%), Positives = 62/116 (53%), Gaps = 12/116 (10%)
 Frame = +2

Query: 44  VVGRPDMTIVAFGS--DVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDDFL 217
           ++G P ++++AF S  D ++ +++ D M ++GWHLNALQ P +IH   T+    AVD  +
Sbjct: 446 IIGYPMVSVIAFTSKNDEIETYDIADAMDARGWHLNALQSPPAIHCAFTIPTAEAVDGLI 505

Query: 218 KDLKESVETV------KKNPGP----ISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
            DL + +  +      +K  G       G  A +YG  G + DR MV +    F+D
Sbjct: 506 SDLIDVISEILLQIQEQKQKGEHIVRQRGKSAALYGVGGSIADRTMVNQFAEGFLD 561

[147][TOP]
>UniRef100_C5M7V2 Sphingosine-1-phosphate lyase n=1 Tax=Candida tropicalis MYA-3404
           RepID=C5M7V2_CANTT
          Length = 596

 Score = 70.5 bits (171), Expect = 5e-11
 Identities = 38/119 (31%), Positives = 64/119 (53%), Gaps = 13/119 (10%)
 Frame = +2

Query: 38  LFVVGRPDMTIVAFG-----SDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPA 202
           L ++G P  ++VAF       D L I+E++D++S KGWH + LQ P+++H  +T   VP 
Sbjct: 473 LEIIGDPIGSVVAFKVRLDQEDHLSIYEISDLLSKKGWHFSTLQNPSALHFAITRLTVPV 532

Query: 203 VDDFLKDL----KESVETVKK----NPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           +D  ++DL    +E+V   ++    N        A +YG AG +   G+   L+  F+D
Sbjct: 533 IDQLIEDLAGCTEEAVRIAEEQRNGNIKKKQSDTAALYGIAGSVHTAGLADRLIAAFLD 591

[148][TOP]
>UniRef100_B8NX23 Sphingosine phosphate lyase, putative n=1 Tax=Aspergillus flavus
           NRRL3357 RepID=B8NX23_ASPFN
          Length = 566

 Score = 70.5 bits (171), Expect = 5e-11
 Identities = 38/116 (32%), Positives = 62/116 (53%), Gaps = 12/116 (10%)
 Frame = +2

Query: 44  VVGRPDMTIVAFGS--DVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDDFL 217
           ++G P ++++AF S  D ++ +++ D M ++GWHLNALQ P +IH   T+    AVD  +
Sbjct: 446 IIGYPMVSVIAFTSKNDEIETYDIADAMDARGWHLNALQSPPAIHCAFTIPTAEAVDGLI 505

Query: 218 KDLKESVETV------KKNPGP----ISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
            DL + +  +      +K  G       G  A +YG  G + DR MV +    F+D
Sbjct: 506 SDLIDVISEILLQIQEQKQKGEHIVRQRGKSAALYGVGGSIADRTMVNQFAEGFLD 561

[149][TOP]
>UniRef100_Q59SV5 Putative uncharacterized protein DPL1 n=1 Tax=Candida albicans
           RepID=Q59SV5_CANAL
          Length = 589

 Score = 70.1 bits (170), Expect = 7e-11
 Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 13/119 (10%)
 Frame = +2

Query: 38  LFVVGRPDMTIVAFG-----SDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPA 202
           L ++G P  ++++F      S  L I+E++D+++ KGWH   LQ P+++H   T   VP 
Sbjct: 466 LQIIGDPIGSVISFQLAPQQSGNLSIYEISDLLTKKGWHFATLQNPSALHFAFTRLTVPV 525

Query: 203 VDDFLKDLKESV--------ETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           VD+ + DL E+         E  K       G  A +YG AG +   G+   L+V F+D
Sbjct: 526 VDELIADLVEATKEAVAIAEEHKKNGVTKAPGDTAALYGIAGSVHTAGLADRLIVAFLD 584

[150][TOP]
>UniRef100_Q59SR8 Putative uncharacterized protein DPL1 n=1 Tax=Candida albicans
           RepID=Q59SR8_CANAL
          Length = 589

 Score = 70.1 bits (170), Expect = 7e-11
 Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 13/119 (10%)
 Frame = +2

Query: 38  LFVVGRPDMTIVAFG-----SDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPA 202
           L ++G P  ++++F      S  L I+E++D+++ KGWH   LQ P+++H   T   VP 
Sbjct: 466 LQIIGDPIGSVISFQLAPQQSGNLSIYEISDLLTKKGWHFATLQNPSALHFAFTRLTVPV 525

Query: 203 VDDFLKDLKESV--------ETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           VD+ + DL E+         E  K       G  A +YG AG +   G+   L+V F+D
Sbjct: 526 VDELIADLVEATKEAVAIAEEHKKNGVTKAPGDTAALYGIAGSVHTAGLADRLIVAFLD 584

[151][TOP]
>UniRef100_C4YQC8 Sphingosine-1-phosphate lyase n=1 Tax=Candida albicans
           RepID=C4YQC8_CANAL
          Length = 589

 Score = 70.1 bits (170), Expect = 7e-11
 Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 13/119 (10%)
 Frame = +2

Query: 38  LFVVGRPDMTIVAFG-----SDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPA 202
           L ++G P  ++++F      S  L I+E++D+++ KGWH   LQ P+++H   T   VP 
Sbjct: 466 LQIIGDPIGSVISFQLAPQQSGNLSIYEISDLLTKKGWHFATLQNPSALHFAFTRLTVPV 525

Query: 203 VDDFLKDLKESV--------ETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           VD+ + DL E+         E  K       G  A +YG AG +   G+   L+V F+D
Sbjct: 526 VDELIADLVEATKEAVAIAEEHKKNGVTKAPGDTAALYGIAGSVHTAGLADRLIVAFLD 584

[152][TOP]
>UniRef100_Q8X074 Probable sphingosine-1-phosphate lyase n=1 Tax=Neurospora crassa
           RepID=Q8X074_NEUCR
          Length = 576

 Score = 69.7 bits (169), Expect = 9e-11
 Identities = 43/126 (34%), Positives = 68/126 (53%), Gaps = 19/126 (15%)
 Frame = +2

Query: 35  ELFVVGRPDMTIVAFGS-DVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDD 211
           EL ++G P ++++AF +   L+I+++ D MSS+GWHLNALQ P +IH+ VT  +    + 
Sbjct: 446 ELEILGNPLVSVLAFQARGDLNIYDIADGMSSRGWHLNALQNPPAIHVAVTAPVAKNWER 505

Query: 212 FLKDL---------KESVETV---------KKNPGPISGGLAPIYGAAGKMPDRGMVQEL 337
             +DL         KE V  V         K      +G  A +YG AG +P++ +V +L
Sbjct: 506 LAQDLEGVVEEEREKERVRQVEALKMGISGKTGKQKAAGDTAALYGVAGSLPNKSVVVDL 565

Query: 338 LVDFMD 355
              F+D
Sbjct: 566 ARGFLD 571

[153][TOP]
>UniRef100_C6ZD42 Sphingosine 1-phosphate lyase n=1 Tax=Fluoribacter dumoffii
           RepID=C6ZD42_9GAMM
          Length = 597

 Score = 68.9 bits (167), Expect = 2e-10
 Identities = 37/106 (34%), Positives = 64/106 (60%), Gaps = 4/106 (3%)
 Frame = +2

Query: 35  ELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT--LQLVPAVD 208
           ++++ G P  +++ F SD L+   + + +  +GW LN+LQ+P+  H+C+T    LV   +
Sbjct: 452 DIYIFGNPQWSVLGFRSDTLNPHFIANELDKRGWKLNSLQKPDGFHLCLTHVHTLVDRFE 511

Query: 209 D-FLKDLKESVETVKKNPGPIS-GGLAPIYGAAGKMPDRGMVQELL 340
           D F+KDL+ES+E VK+ P      G   +YG  G +P +  VQE++
Sbjct: 512 DKFIKDLQESIEAVKQYPADKKPEGNVKVYGTIGILPTQ--VQEVI 555

[154][TOP]
>UniRef100_Q4Q758 Sphingosine phosphate lyase-like protein, putative n=1
           Tax=Leishmania major RepID=Q4Q758_LEIMA
          Length = 537

 Score = 68.9 bits (167), Expect = 2e-10
 Identities = 41/129 (31%), Positives = 73/129 (56%), Gaps = 11/129 (8%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           +++ + + ++  + ++G P  ++ AF S+V+DIF + D +  +GW LN LQ P  +   V
Sbjct: 404 ETMTRELSKLPYIRIIGEPAASVFAFTSNVIDIFRLGDDLKLRGWVLNTLQFPPGLQFSV 463

Query: 182 T-LQLVPAVD-DFLKDLK--------ESVETVKKNPGPISG-GLAPIYGAAGKMPDRGMV 328
           T LQ  PAV   FL D+K        ES + +     P+ G     +YG A ++PDR ++
Sbjct: 464 TLLQTPPAVTARFLSDVKEIGDILFAESEKLIADGKKPVLGESSGTLYGTAQRVPDRTIM 523

Query: 329 QELLVDFMD 355
           Q++L +F++
Sbjct: 524 QDVLREFLN 532

[155][TOP]
>UniRef100_C4I9Q9 Sphingosine-1-phosphate lyase (SP-lyase)
           (SPL)(Sphingosine-1-phosphate aldolase) n=1
           Tax=Burkholderia pseudomallei MSHR346 RepID=C4I9Q9_BURPS
          Length = 493

 Score = 68.2 bits (165), Expect = 3e-10
 Identities = 44/105 (41%), Positives = 60/105 (57%), Gaps = 6/105 (5%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           +Q  +  I EL V+G+P     AF SD  DI+ VND M  +GW  N LQ P+++H+CVT 
Sbjct: 368 MQAAVRSIPELRVLGKPTFCF-AFASDAFDIYHVNDFMRQRGWRFNGLQHPDALHMCVTG 426

Query: 185 LQLVPAV-DDFLKDLKESVETV--KKNPGPISGGLAPIYG--AAG 304
            Q  P V + F +DL E+VE    + +  P S G   +YG  AAG
Sbjct: 427 PQTQPGVAEQFRQDLGEAVEHARHRAHARPQSSG---VYGGDAAG 468

[156][TOP]
>UniRef100_Q3JJF7 Pyridoxal-dependent decarboxylase conserved domain n=3
           Tax=Burkholderia pseudomallei RepID=Q3JJF7_BURP1
          Length = 473

 Score = 68.2 bits (165), Expect = 3e-10
 Identities = 45/105 (42%), Positives = 62/105 (59%), Gaps = 6/105 (5%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           +Q  +  I EL V+G+P     AF SD  DI+ VND M  +GW LN L+RP+++H+CVT 
Sbjct: 348 MQAAVRAIPELRVLGKPTFCF-AFTSDAFDIYHVNDFMRQRGWRLNGLRRPDALHMCVTG 406

Query: 185 LQLVPAV-DDFLKDLKESVETV--KKNPGPISGGLAPIYG--AAG 304
            Q  P V + F +DL E+VE    + +  P S G   +YG  AAG
Sbjct: 407 PQTQPGVAERFRQDLGEAVEHARHRAHARPQSSG---VYGGDAAG 448

[157][TOP]
>UniRef100_Q585W1 Sphingosine phosphate lyase-like protein, putative n=1
           Tax=Trypanosoma brucei RepID=Q585W1_9TRYP
          Length = 538

 Score = 68.2 bits (165), Expect = 3e-10
 Identities = 42/128 (32%), Positives = 74/128 (57%), Gaps = 12/128 (9%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           I   + ++  + ++G+P   + AFGS+++DIF +N+ + S+GW LN LQ P+ +   VT 
Sbjct: 405 ITDALSKLPYIHIIGKPTACVFAFGSNIIDIFVLNEELRSRGWVLNCLQFPSGLQFSVTL 464

Query: 185 LQLVPAV-DDFLKDLKE-------SVETVKKNPGPISGGL---APIYGAAGKMPDRGMVQ 331
           LQ V  V D F++D+ E         E   KN G   G +   + IYG+  K+ DR +++
Sbjct: 465 LQTVGEVADRFIEDVTEIGGRMFAEYEDATKN-GRRHGAVNAKSTIYGSQQKVSDRTIIK 523

Query: 332 ELLVDFMD 355
           ++L +F++
Sbjct: 524 DVLKEFLN 531

[158][TOP]
>UniRef100_C9ZR31 Sphingosine phosphate lyase-like protein, putative n=1
           Tax=Trypanosoma brucei gambiense DAL972
           RepID=C9ZR31_TRYBG
          Length = 538

 Score = 68.2 bits (165), Expect = 3e-10
 Identities = 42/128 (32%), Positives = 74/128 (57%), Gaps = 12/128 (9%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           I   + ++  + ++G+P   + AFGS+++DIF +N+ + S+GW LN LQ P+ +   VT 
Sbjct: 405 ITDALSKLPYIHIIGKPTACVFAFGSNIIDIFVLNEELRSRGWVLNCLQFPSGLQFSVTL 464

Query: 185 LQLVPAV-DDFLKDLKE-------SVETVKKNPGPISGGL---APIYGAAGKMPDRGMVQ 331
           LQ V  V D F++D+ E         E   KN G   G +   + IYG+  K+ DR +++
Sbjct: 465 LQTVGEVADRFIEDVTEIGGRMFAEYEDATKN-GRRHGAVNAKSTIYGSQQKVSDRTIIK 523

Query: 332 ELLVDFMD 355
           ++L +F++
Sbjct: 524 DVLKEFLN 531

[159][TOP]
>UniRef100_A4I5R3 Sphingosine phosphate lyase-like protein, putative n=1
           Tax=Leishmania infantum RepID=A4I5R3_LEIIN
          Length = 537

 Score = 68.2 bits (165), Expect = 3e-10
 Identities = 38/123 (30%), Positives = 70/123 (56%), Gaps = 11/123 (8%)
 Frame = +2

Query: 20  IEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVP 199
           + ++  + ++G P  ++ AF S+V+DIF + D +  +GW LN LQ P+ +   VTL   P
Sbjct: 410 LSKLPYIRIIGEPTASVFAFTSNVIDIFRLGDDLKLRGWVLNTLQFPSGLQFSVTLLQTP 469

Query: 200 --AVDDFLKDLKESVETV-KKNPGPISGGLAPI--------YGAAGKMPDRGMVQELLVD 346
                 FL D+KE  +T+  ++   I+ G  P+        YG A ++PDR +++++L +
Sbjct: 470 TAVTARFLSDVKEIGDTLFAESEKLIADGKKPVLGESSGTLYGTAQRVPDRTIIKDVLRE 529

Query: 347 FMD 355
           F++
Sbjct: 530 FLN 532

[160][TOP]
>UniRef100_A8PQP1 Pyridoxal-dependent decarboxylase conserved domain containing
           protein n=1 Tax=Brugia malayi RepID=A8PQP1_BRUMA
          Length = 570

 Score = 67.4 bits (163), Expect = 5e-10
 Identities = 40/121 (33%), Positives = 69/121 (57%), Gaps = 3/121 (2%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICV 181
           + I+ GIE+   + ++   D+T VAF +  L+++ + D M+  GW L+ LQ P ++HICV
Sbjct: 426 REIRTGIEKCLHIQLLCESDVTTVAFTTRGLNVYALADRMNKLGWVLSTLQNPPAVHICV 485

Query: 182 TLQLVPA--VDDFLKDLKESVETVKKNPG-PISGGLAPIYGAAGKMPDRGMVQELLVDFM 352
           TL    +  V++FL++L  + E +  NP        A IYG    +PD  +V+E+   ++
Sbjct: 486 TLNHTKSGVVENFLRELNMACEDLVSNPEFSHQSRTAAIYGMVSAVPD--LVEEISQMYL 543

Query: 353 D 355
           D
Sbjct: 544 D 544

[161][TOP]
>UniRef100_B2HAT7 Sphingosine-1-phosphate lyase n=1 Tax=Burkholderia pseudomallei
           1655 RepID=B2HAT7_BURPS
          Length = 493

 Score = 67.0 bits (162), Expect = 6e-10
 Identities = 44/105 (41%), Positives = 60/105 (57%), Gaps = 6/105 (5%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           +Q  +  I EL V+G+P     AF SD  DI+ VND M  +GW  N LQ P+++H+CVT 
Sbjct: 368 MQAAVRAIPELRVLGKPTFCF-AFASDAFDIYHVNDFMRQRGWRFNGLQHPDALHMCVTG 426

Query: 185 LQLVPAV-DDFLKDLKESVETV--KKNPGPISGGLAPIYG--AAG 304
            Q  P V + F +DL E+VE    + +  P S G   +YG  AAG
Sbjct: 427 PQTQPGVAERFRQDLGEAVEHARHRAHARPQSSG---VYGGDAAG 468

[162][TOP]
>UniRef100_UPI00016A8CCF sphingosine-1-phosphate lyase n=1 Tax=Burkholderia oklahomensis
           EO147 RepID=UPI00016A8CCF
          Length = 473

 Score = 66.6 bits (161), Expect = 8e-10
 Identities = 43/100 (43%), Positives = 56/100 (56%), Gaps = 4/100 (4%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           IQ  +  I EL V+G+P     AF SD  DI+ VND M   GW  N LQ P+++H+CVT 
Sbjct: 348 IQAAVLAIPELRVLGKPTFCF-AFTSDAFDIYHVNDCMRRHGWRFNGLQHPDALHLCVTG 406

Query: 185 LQLVP-AVDDFLKDLKESVETVKK--NPGPISGGLAPIYG 295
            Q  P  V+ F  DL E+VE  ++  N  P S G   +YG
Sbjct: 407 PQTQPGVVERFRDDLGEAVEYARRHANARPKSSG---VYG 443

[163][TOP]
>UniRef100_UPI00006CC4BC Pyridoxal-dependent decarboxylase conserved domain containing
           protein n=1 Tax=Tetrahymena thermophila
           RepID=UPI00006CC4BC
          Length = 547

 Score = 66.2 bits (160), Expect = 1e-09
 Identities = 38/121 (31%), Positives = 66/121 (54%), Gaps = 5/121 (4%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFG---SDVLDIFEVNDIMSS-KGWHLNALQRPNSIHI 175
           I+  I +I EL ++G P  TI+AF    +  ++I+ ++D +     W +   + P  IHI
Sbjct: 415 IRDEIRKIEELEILGNPVTTIIAFRVKKNQEINIYHISDALKDINDWQVENQRFPECIHI 474

Query: 176 CVTLQLVPAVDDFLKDLKESVETVKKNPGPIS-GGLAPIYGAAGKMPDRGMVQELLVDFM 352
               Q +   + F+ DLK+++  VK+NP   +  G A +YG  G +PD  +++E +  FM
Sbjct: 475 SFMPQHLQIKEQFIIDLKKAINIVKENPKKYAKDGTAAMYGMMGMVPDEEVLEEFMAHFM 534

Query: 353 D 355
           D
Sbjct: 535 D 535

[164][TOP]
>UniRef100_A3NNI2 Sphingosine-1-phosphate lyase n=1 Tax=Burkholderia pseudomallei 668
           RepID=A3NNI2_BURP6
          Length = 473

 Score = 66.2 bits (160), Expect = 1e-09
 Identities = 44/105 (41%), Positives = 60/105 (57%), Gaps = 6/105 (5%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           +Q  +  I EL V+G+P     AF SD  DI+ VND M  +GW  N LQ P+++H+CVT 
Sbjct: 348 MQAAVRAIPELRVLGKPTFCF-AFTSDAFDIYHVNDFMRQRGWRFNGLQHPDALHMCVTG 406

Query: 185 LQLVPAV-DDFLKDLKESVETV--KKNPGPISGGLAPIYG--AAG 304
            Q  P V + F +DL E+VE    + +  P S G   +YG  AAG
Sbjct: 407 PQTQPGVAERFRQDLGEAVEHARHRAHARPQSSG---VYGGDAAG 448

[165][TOP]
>UniRef100_A3P8X5 Sphingosine-1-phosphate lyase n=5 Tax=Burkholderia pseudomallei
           RepID=A3P8X5_BURP0
          Length = 473

 Score = 66.2 bits (160), Expect = 1e-09
 Identities = 44/105 (41%), Positives = 60/105 (57%), Gaps = 6/105 (5%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           +Q  +  I EL V+G+P     AF SD  DI+ VND M  +GW  N LQ P+++H+CVT 
Sbjct: 348 MQAAVRAIPELRVLGKPTFCF-AFTSDAFDIYHVNDFMRQRGWRFNGLQHPDALHMCVTG 406

Query: 185 LQLVPAV-DDFLKDLKESVETV--KKNPGPISGGLAPIYG--AAG 304
            Q  P V + F +DL E+VE    + +  P S G   +YG  AAG
Sbjct: 407 PQTQPGVAERFRQDLGEAVEHARHRAHARPQSSG---VYGGDAAG 448

[166][TOP]
>UniRef100_B1H9D7 Sphingosine-1-phosphate lyase n=2 Tax=Burkholderia pseudomallei
           RepID=B1H9D7_BURPS
          Length = 493

 Score = 66.2 bits (160), Expect = 1e-09
 Identities = 44/105 (41%), Positives = 60/105 (57%), Gaps = 6/105 (5%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           +Q  +  I EL V+G+P     AF SD  DI+ VND M  +GW  N LQ P+++H+CVT 
Sbjct: 368 MQAAVRAIPELRVLGKPTFCF-AFTSDAFDIYHVNDFMRQRGWRFNGLQHPDALHMCVTG 426

Query: 185 LQLVPAV-DDFLKDLKESVETV--KKNPGPISGGLAPIYG--AAG 304
            Q  P V + F +DL E+VE    + +  P S G   +YG  AAG
Sbjct: 427 PQTQPGVAERFRQDLGEAVEHARHRAHARPQSSG---VYGGDAAG 468

[167][TOP]
>UniRef100_A4LG68 Sphingosine-1-phosphate lyase n=1 Tax=Burkholderia pseudomallei 305
           RepID=A4LG68_BURPS
          Length = 473

 Score = 66.2 bits (160), Expect = 1e-09
 Identities = 44/105 (41%), Positives = 60/105 (57%), Gaps = 6/105 (5%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           +Q  +  I EL V+G+P     AF SD  DI+ VND M  +GW  N LQ P+++H+CVT 
Sbjct: 348 MQAAVRAIPELRVLGKPTFCF-AFTSDAFDIYHVNDFMRQRGWRFNGLQHPDALHMCVTG 406

Query: 185 LQLVPAV-DDFLKDLKESVETV--KKNPGPISGGLAPIYG--AAG 304
            Q  P V + F +DL E+VE    + +  P S G   +YG  AAG
Sbjct: 407 PQTQPGVAERFRQDLGEAVEHARHRAHARPQSSG---VYGGDAAG 448

[168][TOP]
>UniRef100_Q5WUR6 Probable sphingosine-1-phosphate lyase n=1 Tax=Legionella
           pneumophila str. Lens RepID=SGPL_LEGPL
          Length = 605

 Score = 66.2 bits (160), Expect = 1e-09
 Identities = 36/97 (37%), Positives = 55/97 (56%), Gaps = 4/97 (4%)
 Frame = +2

Query: 35  ELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT--LQLVPAVD 208
           +++V G P  +I+ F S+  +   + D +  +GW LN LQ P+  H+C+T    LV   +
Sbjct: 455 DIYVYGNPQWSILGFRSNTCNAHFIADELEKRGWKLNLLQNPDGFHLCLTHVHTLVRGFE 514

Query: 209 -DFLKDLKESVETVKK-NPGPISGGLAPIYGAAGKMP 313
             F+KDL+E+V  VK   PG  + G   +YGA G MP
Sbjct: 515 TQFIKDLREAVIDVKNYPPGKKASGNVKVYGAVGMMP 551

[169][TOP]
>UniRef100_C4M8C7 S phingosine-1-phosphate lyase 1, putative n=1 Tax=Entamoeba
           histolytica HM-1:IMSS RepID=C4M8C7_ENTHI
          Length = 514

 Score = 65.9 bits (159), Expect = 1e-09
 Identities = 34/126 (26%), Positives = 71/126 (56%), Gaps = 8/126 (6%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVG--RPDMTIVAFGSDVLDIFEVNDIMSSK-GWHLNALQRPNSIH 172
           K+++  + +++ + ++     D  +VAF +  L+I++V+D M+ +  W  N LQ P ++H
Sbjct: 387 KNLKNELSKMSNIKILNDMEQDTPVVAFTTTDLNIYKVSDCMNKEFQWEFNTLQFPAAVH 446

Query: 173 ICVTLQLVPAVDDFLKDLKESVETVKKNP-GPISGGLAPIYGAAGKMPD----RGMVQEL 337
            CVT + +     F++DL ++++ ++K+P  P     AP+YG    +PD      MV ++
Sbjct: 447 FCVTEKTIGCEKQFMEDLNKALDIIRKDPKNPKYNVWAPVYGMTSSLPDIDTLEDMVSQV 506

Query: 338 LVDFMD 355
           +  + D
Sbjct: 507 IAQYCD 512

[170][TOP]
>UniRef100_B0EIY0 Sphingosine-1-phosphate lyase, putative n=1 Tax=Entamoeba dispar
           SAW760 RepID=B0EIY0_ENTDI
          Length = 514

 Score = 65.9 bits (159), Expect = 1e-09
 Identities = 34/126 (26%), Positives = 71/126 (56%), Gaps = 8/126 (6%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVG--RPDMTIVAFGSDVLDIFEVNDIMSSK-GWHLNALQRPNSIH 172
           K+++  + +++ + ++     D  +VAF +  L+I++V+D M+ +  W  N LQ P ++H
Sbjct: 387 KNLKNELSKMSNIKILNDMEQDTPVVAFTTTDLNIYKVSDCMNKEFQWEFNTLQFPAAVH 446

Query: 173 ICVTLQLVPAVDDFLKDLKESVETVKKNP-GPISGGLAPIYGAAGKMPD----RGMVQEL 337
            CVT + +     F++DL ++++ ++K+P  P     AP+YG    +PD      MV ++
Sbjct: 447 FCVTEKTIGCEKQFIEDLNKALDIIRKDPKNPKYNVWAPVYGMTSSLPDIDTLEDMVSQV 506

Query: 338 LVDFMD 355
           +  + D
Sbjct: 507 IAQYCD 512

[171][TOP]
>UniRef100_B9WDX2 Sphingosine-1-phosphate lyase, putative (Sphingosine-1-phosphate
           aldolase, putative) (Dihydrosphingosine phosphate lyase,
           putative) n=1 Tax=Candida dubliniensis CD36
           RepID=B9WDX2_CANDC
          Length = 589

 Score = 65.9 bits (159), Expect = 1e-09
 Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 13/119 (10%)
 Frame = +2

Query: 38  LFVVGRPDMTIVAFGSDV-----LDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPA 202
           L ++G P  ++++F         L I+E++D+++ KGWH   LQ P+++H   T   VP 
Sbjct: 466 LQIIGDPIGSVISFQLAPQQLGNLSIYEISDLLTKKGWHFATLQNPSALHFAFTRLTVPV 525

Query: 203 VDDFLKDLKESV--------ETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFMD 355
           VD+ + DL ++         E  K       G  A +YG AG +   G+   L+V F+D
Sbjct: 526 VDELIADLVDATKEAAAIAEEHKKNGVTKPPGDTAALYGIAGSVHTAGLADRLIVAFLD 584

[172][TOP]
>UniRef100_Q5ZTI6 Probable sphingosine-1-phosphate lyase n=1 Tax=Legionella
           pneumophila subsp. pneumophila str. Philadelphia 1
           RepID=SGPL_LEGPH
          Length = 601

 Score = 65.9 bits (159), Expect = 1e-09
 Identities = 36/97 (37%), Positives = 54/97 (55%), Gaps = 4/97 (4%)
 Frame = +2

Query: 35  ELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT--LQLVPAVD 208
           +++V G P  +I+ F S+  +   + D +  +GW LN LQ P+  H+C+T    LV   +
Sbjct: 455 DIYVYGNPQWSILGFRSNTCNAHFIADELEKRGWKLNLLQNPDGFHLCLTHVHTLVKGFE 514

Query: 209 -DFLKDLKESVETVKK-NPGPISGGLAPIYGAAGKMP 313
             F+KDL+E+V  VK   PG    G   +YGA G MP
Sbjct: 515 TQFIKDLREAVIDVKNYPPGKKPSGNVKVYGAVGMMP 551

[173][TOP]
>UniRef100_Q5X3A8 Probable sphingosine-1-phosphate lyase n=1 Tax=Legionella
           pneumophila str. Paris RepID=SGPL_LEGPA
          Length = 605

 Score = 65.9 bits (159), Expect = 1e-09
 Identities = 36/97 (37%), Positives = 55/97 (56%), Gaps = 4/97 (4%)
 Frame = +2

Query: 35  ELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT--LQLVPAVD 208
           +++V G P  +I+ F S+  +   + D +  +GW LN LQ P+  H+C+T    LV + +
Sbjct: 455 DIYVYGNPQWSILGFRSNTCNAHFIADELEKRGWKLNLLQNPDGFHLCLTHVHTLVGSFE 514

Query: 209 -DFLKDLKESVETVKK-NPGPISGGLAPIYGAAGKMP 313
             F+KDL+E+V  VK   PG    G   +YGA G MP
Sbjct: 515 TQFIKDLREAVIDVKNYPPGKKPSGNVKVYGAVGMMP 551

[174][TOP]
>UniRef100_B1N3J5 Sphingosine-1-phosphate lyase, putative n=1 Tax=Entamoeba
           histolytica HM-1:IMSS RepID=B1N3J5_ENTHI
          Length = 110

 Score = 65.5 bits (158), Expect = 2e-09
 Identities = 33/105 (31%), Positives = 60/105 (57%), Gaps = 6/105 (5%)
 Frame = +2

Query: 59  DMTIVAFGSDVLDIFEVNDIMSSK-GWHLNALQRPNSIHICVTLQLVPAVDDFLKDLKES 235
           D  +VAF +  L+I++V+D M+ +  W  N LQ P ++H CVT + +     F++DL ++
Sbjct: 4   DTPVVAFTTTDLNIYKVSDCMNKEFQWEFNTLQFPAAVHFCVTEKTIGCEKQFMEDLNKA 63

Query: 236 VETVKKNP-GPISGGLAPIYGAAGKMPD----RGMVQELLVDFMD 355
           ++ ++K+P  P     AP+YG    +PD      MV +++  + D
Sbjct: 64  LDIIRKDPKNPKYNVWAPVYGMTSSLPDIDTLEDMVSQVIAQYCD 108

[175][TOP]
>UniRef100_Q2T8I9 Sphingosine-1-phosphate lyase n=1 Tax=Burkholderia thailandensis
           E264 RepID=Q2T8I9_BURTA
          Length = 473

 Score = 64.7 bits (156), Expect = 3e-09
 Identities = 35/85 (41%), Positives = 51/85 (60%), Gaps = 2/85 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           +Q  +  I EL V+G+P     AF SD  DI+ VND M  +GW LN L+ P+++ +CVT 
Sbjct: 348 MQAAVRAIPELRVLGKPTFCF-AFASDAFDIYHVNDFMRQRGWRLNGLRHPDALQMCVTE 406

Query: 185 LQLVPAV-DDFLKDLKESVETVKKN 256
            Q  P V D F +DL  +VE  +++
Sbjct: 407 PQTRPGVADQFRRDLGAAVEHARRH 431

[176][TOP]
>UniRef100_C5JIJ1 Sphinganine-1-phosphate aldolase BST1 n=1 Tax=Ajellomyces
           dermatitidis SLH14081 RepID=C5JIJ1_AJEDS
          Length = 569

 Score = 64.7 bits (156), Expect = 3e-09
 Identities = 37/108 (34%), Positives = 59/108 (54%), Gaps = 12/108 (11%)
 Frame = +2

Query: 38  LFVVGRPDMTIVAFGSDV--LDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVDD 211
           L V+G+P +++VA+ S    +DI+++ D +S+KGWHLNALQ P +IH+  T+    AV+ 
Sbjct: 462 LKVLGKPMVSVVAWDSATPEIDIYDIADALSAKGWHLNALQAPPAIHVAFTVPTAGAVEK 521

Query: 212 FLKDLKESVETVKKNPGPI----------SGGLAPIYGAAGKMPDRGM 325
            + DL   VE  ++                G  A +YG AG +  R +
Sbjct: 522 LIADLVAVVEQEREKAAERKRLGLKVEKGKGDAAALYGVAGSILIRAL 569

[177][TOP]
>UniRef100_UPI00016ACD98 sphingosine-1-phosphate lyase n=1 Tax=Burkholderia thailandensis
           MSMB43 RepID=UPI00016ACD98
          Length = 473

 Score = 63.9 bits (154), Expect = 5e-09
 Identities = 34/85 (40%), Positives = 51/85 (60%), Gaps = 2/85 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           +Q  +  I EL V+G+P     AF SD  D++ VND M   GW  N LQ P+++H+CVT 
Sbjct: 348 MQAAVRAIPELRVLGKPTFCF-AFASDAFDVYHVNDYMRRHGWRFNGLQHPDALHMCVTG 406

Query: 185 LQLVPAV-DDFLKDLKESVETVKKN 256
            Q  P V + F +DL E+V+  +++
Sbjct: 407 PQTRPGVAERFRQDLGEAVDYARRH 431

[178][TOP]
>UniRef100_UPI00016A8008 sphingosine-1-phosphate lyase n=1 Tax=Burkholderia oklahomensis
           C6786 RepID=UPI00016A8008
          Length = 473

 Score = 63.9 bits (154), Expect = 5e-09
 Identities = 41/100 (41%), Positives = 55/100 (55%), Gaps = 4/100 (4%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           +Q  +  I EL V+G+P     AF SD  DI+ VND M   GW  N LQ P+++H+CVT 
Sbjct: 348 MQAAVLAIPELRVLGKPTFCF-AFTSDAFDIYHVNDCMRRHGWRFNGLQHPDALHLCVTG 406

Query: 185 LQLVP-AVDDFLKDLKESVETVKK--NPGPISGGLAPIYG 295
            Q  P  V+ F  DL E+ E  ++  N  P S G   +YG
Sbjct: 407 PQTQPGVVERFRDDLGEAAEYARRHANARPKSSG---VYG 443

[179][TOP]
>UniRef100_Q22UE1 Pyridoxal-dependent decarboxylase conserved domain containing
           protein n=1 Tax=Tetrahymena thermophila SB210
           RepID=Q22UE1_TETTH
          Length = 575

 Score = 63.5 bits (153), Expect = 7e-09
 Identities = 39/115 (33%), Positives = 65/115 (56%), Gaps = 7/115 (6%)
 Frame = +2

Query: 26  EIAELFVVGRPDMTIVA--FGSDV-LDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLV 196
           E+ E+ V+G P   +VA  +   V  +I+ +   +S KGW    +QRP +IHI +T  + 
Sbjct: 457 ELQEIDVIGNPKTVVVAIVYKKGVNRNIYHLEGALSQKGWAFAGVQRPAAIHISITHGIA 516

Query: 197 PAVDDFLKDLKESVETVKKNPGPI-SGGLAPIYGAAGKMPDRGMVQ---ELLVDF 349
             V D ++DLK +V+ V +NP    +   + IYGA+ ++PD  ++    E+ VDF
Sbjct: 517 NRVKDLIRDLKLAVKEVAENPEKFKNSSSSSIYGASVQVPDTRILDSMLEICVDF 571

[180][TOP]
>UniRef100_A8XV29 C. briggsae CBR-TAG-38 protein n=1 Tax=Caenorhabditis briggsae
           RepID=A8XV29_CAEBR
          Length = 543

 Score = 63.2 bits (152), Expect = 9e-09
 Identities = 36/123 (29%), Positives = 67/123 (54%), Gaps = 5/123 (4%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDV-LDIFEVNDIMSSKGWHLNALQRPNSIHIC 178
           + I+ G+ +I  + + G  D+ IV++ +D  ++++  ++ M  + W LN LQ P+ +HI 
Sbjct: 414 RKIRDGLSKIKGIKLQGPSDVCIVSWTTDSGVELYRFHNYMKERHWQLNGLQFPSGVHIM 473

Query: 179 VTLQLVP--AVDDFLKDLKESVETVKKNPGPISG--GLAPIYGAAGKMPDRGMVQELLVD 346
           VT+        + F+ D + + + V++NP   S     A IYG A  +PDR +V E    
Sbjct: 474 VTMNHTQPGLAESFIADCQAAADFVRQNPVTESDKKSEAAIYGLAQSIPDRSLVHEFAHS 533

Query: 347 FMD 355
           ++D
Sbjct: 534 YLD 536

[181][TOP]
>UniRef100_A5IDX4 Sphingosine-1-phosphate lyase I n=1 Tax=Legionella pneumophila str.
           Corby RepID=A5IDX4_LEGPC
          Length = 605

 Score = 62.8 bits (151), Expect = 1e-08
 Identities = 34/97 (35%), Positives = 53/97 (54%), Gaps = 4/97 (4%)
 Frame = +2

Query: 35  ELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT--LQLVPAVD 208
           +++V G P  +I+ F S+  +   + D +  +GW LN LQ P+  H+C+T    +V   +
Sbjct: 455 DIYVYGNPQWSILGFRSNTCNAHFIADELEKRGWKLNLLQNPDGFHLCLTHVHTVVKGFE 514

Query: 209 -DFLKDLKESVETVKK-NPGPISGGLAPIYGAAGKMP 313
             F+ DL+E+V  VK   PG    G   +YGA G MP
Sbjct: 515 TQFINDLREAVIDVKNYPPGKKPSGNVKVYGAVGMMP 551

[182][TOP]
>UniRef100_C5L2Y7 Sphingosine phosphate lyase, putative n=1 Tax=Perkinsus marinus
           ATCC 50983 RepID=C5L2Y7_9ALVE
          Length = 393

 Score = 62.8 bits (151), Expect = 1e-08
 Identities = 42/129 (32%), Positives = 70/129 (54%), Gaps = 8/129 (6%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAF----GSDVLDIFEVNDIMSSKGWHLNALQRPNSI 169
           K ++KGI +I  + V+GRP +++VA     G +  D  E     +   W+LN LQ P+ +
Sbjct: 264 KHLEKGINDIEGVRVLGRPSVSVVAITCTNGVNDYDFAEWLKNNTKTHWNLNMLQMPSGV 323

Query: 170 HICVTLQLVPAVDDFLKDLKESV--ETVKKNPGPISG--GLAPIYGAAGKMPDRGMVQEL 337
           HICVT      +D+ L D++  +  E  K + G  SG  G A +YG+A  +P + +   +
Sbjct: 324 HICVTRLNAKKMDELLTDIEAGLKAEKAKLDAGVKSGHSGNAAVYGSAASVP-KELADIV 382

Query: 338 LVDFMDGTC 364
           +  ++D TC
Sbjct: 383 VAKYLD-TC 390

[183][TOP]
>UniRef100_C5KK69 Sphingosine-1-phosphate lyase, putative n=1 Tax=Perkinsus marinus
           ATCC 50983 RepID=C5KK69_9ALVE
          Length = 424

 Score = 62.8 bits (151), Expect = 1e-08
 Identities = 42/129 (32%), Positives = 70/129 (54%), Gaps = 8/129 (6%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAF----GSDVLDIFEVNDIMSSKGWHLNALQRPNSI 169
           K ++KGI +I  + V+GRP +++VA     G +  D  E     +   W+LN LQ P+ +
Sbjct: 295 KHLEKGINDIEGVRVLGRPSVSVVAITCTNGVNDYDFAEWLKNNTKTHWNLNMLQMPSGV 354

Query: 170 HICVTLQLVPAVDDFLKDLKESV--ETVKKNPGPISG--GLAPIYGAAGKMPDRGMVQEL 337
           HICVT      +D+ L D++  +  E  K + G  SG  G A +YG+A  +P + +   +
Sbjct: 355 HICVTRLNAEKMDELLTDIEAGLKAEKAKLDAGVKSGHSGNAAVYGSAASVP-KELADIV 413

Query: 338 LVDFMDGTC 364
           +  ++D TC
Sbjct: 414 VAKYLD-TC 421

[184][TOP]
>UniRef100_A4HIG7 Sphingosine phosphate lyase-like protein,putative n=1
           Tax=Leishmania braziliensis RepID=A4HIG7_LEIBR
          Length = 537

 Score = 62.8 bits (151), Expect = 1e-08
 Identities = 41/122 (33%), Positives = 68/122 (55%), Gaps = 11/122 (9%)
 Frame = +2

Query: 20  IEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT-LQLV 196
           + ++  + ++G P  ++ AF S  +DIF + + +  +GW LN LQ P  +   VT LQ  
Sbjct: 410 LRKLPYIRIIGEPTASVFAFTSSEIDIFLLGEALKLRGWVLNKLQFPCGLQFSVTLLQTP 469

Query: 197 PAVD-DFLKDLKESVETV-KKNPGPISGGLAPI--------YGAAGKMPDRGMVQELLVD 346
           PAV   FL+D+KE   T+  +N   I+ G  PI        YG A ++PD  +V+++L +
Sbjct: 470 PAVTARFLRDVKEIGATLFAENKKLIAAGKKPIVGESSSTLYGTAQRIPDGTIVKDVLRE 529

Query: 347 FM 352
           F+
Sbjct: 530 FL 531

[185][TOP]
>UniRef100_Q2T8I7 Sphingosine-1-phosphate lyase n=1 Tax=Burkholderia thailandensis
           E264 RepID=Q2T8I7_BURTA
          Length = 473

 Score = 62.4 bits (150), Expect = 1e-08
 Identities = 34/85 (40%), Positives = 50/85 (58%), Gaps = 2/85 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           +Q  +  I EL V+G+P     AF SD  DI+ VND M  +GW  N LQ P+++H+CVT 
Sbjct: 348 MQAAVRAIPELRVLGKPTFCF-AFASDAFDIYHVNDFMRRQGWRFNGLQHPDALHMCVTG 406

Query: 185 LQLVPAV-DDFLKDLKESVETVKKN 256
            Q  P V   F +DL  +V+  +++
Sbjct: 407 PQTQPGVAKRFRQDLGAAVDYARRH 431

[186][TOP]
>UniRef100_C6ZD45 Sphingosine 1-phosphate lyase n=1 Tax=Legionella jamestowniensis
           RepID=C6ZD45_9GAMM
          Length = 601

 Score = 62.4 bits (150), Expect = 1e-08
 Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 4/97 (4%)
 Frame = +2

Query: 35  ELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPA---V 205
           +++V G P  +++ F SD L+   + D +  +GW LN LQ P   H+C+T     A    
Sbjct: 453 DIYVYGNPKWSVLGFRSDTLNPHLIADELEKRGWKLNLLQNPAGFHLCLTHVHTLAEGFE 512

Query: 206 DDFLKDLKESVETVKKNPGPIS-GGLAPIYGAAGKMP 313
           D F+ DL ++V  VK+ P      G   +YGA G MP
Sbjct: 513 DKFISDLGDAVIAVKQYPADKKPSGNVKVYGAVGTMP 549

[187][TOP]
>UniRef100_A3NNI8 Sphingosine-1-phosphate lyase n=1 Tax=Burkholderia pseudomallei 668
           RepID=A3NNI8_BURP6
          Length = 485

 Score = 61.6 bits (148), Expect = 3e-08
 Identities = 33/75 (44%), Positives = 46/75 (61%), Gaps = 2/75 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           +Q  +  I EL V+G+P     AF SD  DI+ VND M  +GW LN L+RP+++ +CVT 
Sbjct: 360 MQAAVRAIPELRVLGKPTFCF-AFASDAFDIYHVNDFMRQRGWRLNGLRRPDALQMCVTG 418

Query: 185 LQLVPAV-DDFLKDL 226
            Q  P V + F +DL
Sbjct: 419 PQTQPGVAEQFRRDL 433

[188][TOP]
>UniRef100_C2AHR3 PLP-dependent enzyme, glutamate decarboxylase n=1
           Tax=Thermomonospora curvata DSM 43183 RepID=C2AHR3_THECU
          Length = 468

 Score = 61.6 bits (148), Expect = 3e-08
 Identities = 42/125 (33%), Positives = 66/125 (52%), Gaps = 9/125 (7%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTL 187
           +Q+ +    +L ++G P   + +F SD  DI+ V D M+ +GW  N  Q PN+IH+ VTL
Sbjct: 336 MQQAVRSHPQLRILGEPTF-LFSFTSDEFDIYHVYDFMAGRGWRFNGQQYPNAIHMAVTL 394

Query: 188 -QLVPAV-DDFLKDLKESVETVKKNPG----PISGGLAPIYGAA-GKMPDRG--MVQELL 340
            Q  P V ++F  DL E+V   +K       P SG    IYG   G + D     +++++
Sbjct: 395 PQTRPGVTEEFAADLAEAVAYAQKQHAAGARPHSGA---IYGGVPGGLTDEADEFIRQIM 451

Query: 341 VDFMD 355
            D +D
Sbjct: 452 ADMLD 456

[189][TOP]
>UniRef100_A4LG74 Sphingosine-1-phosphate lyase n=1 Tax=Burkholderia pseudomallei 305
           RepID=A4LG74_BURPS
          Length = 507

 Score = 61.6 bits (148), Expect = 3e-08
 Identities = 33/75 (44%), Positives = 46/75 (61%), Gaps = 2/75 (2%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT- 184
           +Q  +  I EL V+G+P     AF SD  DI+ VND M  +GW LN L+RP+++ +CVT 
Sbjct: 382 MQAAVRAIPELRVLGKPTFCF-AFASDAFDIYHVNDFMRQRGWRLNGLRRPDALQMCVTG 440

Query: 185 LQLVPAV-DDFLKDL 226
            Q  P V + F +DL
Sbjct: 441 PQTQPGVAEQFRRDL 455

[190][TOP]
>UniRef100_A9UT87 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9UT87_MONBE
          Length = 456

 Score = 61.6 bits (148), Expect = 3e-08
 Identities = 33/119 (27%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAF--GSDVLDIFEVNDIMSSKGWHLNALQRPNSIHI 175
           ++I++ + EI  + ++G P MT ++    S  +++  + D+M  +GW L   Q P+S+H+
Sbjct: 334 EAIKRAVGEIEGIKILGTPHMTGISIVSASPQINVLILGDMMEKRGWKLEMQQNPSSLHL 393

Query: 176 CVTLQLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFM 352
            +    V  V D + DL+E     K +      G+A +YG    +PD  +V + L   M
Sbjct: 394 SIMPHHVARVQDLVADLRELAMGKKAD----DEGMAAMYGMTANIPDSSIVSDFLAKLM 448

[191][TOP]
>UniRef100_Q17456 Temporarily assigned gene name protein 38 n=1 Tax=Caenorhabditis
           elegans RepID=Q17456_CAEEL
          Length = 542

 Score = 60.5 bits (145), Expect = 6e-08
 Identities = 38/123 (30%), Positives = 64/123 (52%), Gaps = 5/123 (4%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGS-DVLDIFEVNDIMSSKGWHLNALQRPNSIHIC 178
           + I+ G+  I  + + G  D+ IV++ + D ++++  ++ M  K W LN LQ P  +HI 
Sbjct: 413 RKIRNGLSNIKGIKLQGPSDVCIVSWTTNDGVELYRFHNFMKEKHWQLNGLQFPAGVHIM 472

Query: 179 VTLQLV--PAVDDFLKDLKESVETVKKNPGPISG--GLAPIYGAAGKMPDRGMVQELLVD 346
           VT+        + F+ D + +VE VK +    S     A IYG A  +PDR +V E    
Sbjct: 473 VTMNHTHPGLAEAFVADCRAAVEFVKSHKPSESDKTSEAAIYGLAQSIPDRSLVHEFAHS 532

Query: 347 FMD 355
           ++D
Sbjct: 533 YID 535

[192][TOP]
>UniRef100_B2HAT2 Sphingosine-1-phosphate lyase n=1 Tax=Burkholderia pseudomallei
           1655 RepID=B2HAT2_BURPS
          Length = 485

 Score = 60.1 bits (144), Expect = 7e-08
 Identities = 27/59 (45%), Positives = 38/59 (64%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT 184
           +Q  +  I EL V+G+P     AF SD  DI+ VND M  +GW LN L+RP+++ +CVT
Sbjct: 360 MQAAVRAIPELRVLGKPTFCF-AFASDAFDIYHVNDFMRQRGWRLNGLRRPDALQMCVT 417

[193][TOP]
>UniRef100_Q54VR5 Sphingosine-1-phosphate lyase n=1 Tax=Dictyostelium discoideum
           RepID=Q54VR5_DICDI
          Length = 531

 Score = 59.7 bits (143), Expect = 1e-07
 Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 4/123 (3%)
 Frame = +2

Query: 5   SIQKGIEEI--AELFVVG-RPDMTIVAFGSDVLDIFEVNDIMSSK-GWHLNALQRPNSIH 172
           +IQKGI  +    + ++G  P M+I++  S V++I  V D M     W L    RPNSIH
Sbjct: 406 AIQKGIVSLPLGNVEIIGSNPVMSIISLRSKVVNIHAVADSMEKHFSWKLERQHRPNSIH 465

Query: 173 ICVTLQLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELLVDFM 352
           + +T   +     FL++LK S++ V  +P     G A +Y     +P   +  + L++F+
Sbjct: 466 MTLTPSHIGIEKVFLENLKFSIQEVMADPNLSKKGSAAMYNGINNIPLTAIADDFLIEFL 525

Query: 353 DGT 361
             T
Sbjct: 526 SKT 528

[194][TOP]
>UniRef100_A3P8Y1 Sphingosine-1-phosphate lyase n=2 Tax=Burkholderia pseudomallei
           RepID=A3P8Y1_BURP0
          Length = 498

 Score = 59.3 bits (142), Expect = 1e-07
 Identities = 27/59 (45%), Positives = 38/59 (64%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT 184
           +Q  +  I EL V+G+P     AF SD  DI+ VND M  +GW LN L+RP+++ +CVT
Sbjct: 373 MQAAVRAIPELRVLGKPTFCF-AFTSDAFDIYHVNDFMRQRGWRLNGLRRPDALQMCVT 430

[195][TOP]
>UniRef100_C4I9R5 Sphinganine-1-phosphate aldolase n=1 Tax=Burkholderia pseudomallei
           MSHR346 RepID=C4I9R5_BURPS
          Length = 485

 Score = 59.3 bits (142), Expect = 1e-07
 Identities = 27/59 (45%), Positives = 38/59 (64%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT 184
           +Q  +  I EL V+G+P     AF SD  DI+ VND M  +GW LN L+RP+++ +CVT
Sbjct: 360 MQAAVRAIPELRVLGKPTFCF-AFTSDAFDIYHVNDFMRQRGWRLNGLRRPDALQMCVT 417

[196][TOP]
>UniRef100_C0Y786 Putative sphinganine-1-phosphate aldolase n=2 Tax=Burkholderia
           pseudomallei RepID=C0Y786_BURPS
          Length = 507

 Score = 59.3 bits (142), Expect = 1e-07
 Identities = 27/59 (45%), Positives = 38/59 (64%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT 184
           +Q  +  I EL V+G+P     AF SD  DI+ VND M  +GW LN L+RP+++ +CVT
Sbjct: 382 MQAAVRAIPELRVLGKPTFCF-AFTSDAFDIYHVNDFMRQRGWRLNGLRRPDALQMCVT 439

[197][TOP]
>UniRef100_B1H9E3 Sphingosine-1-phosphate lyase n=2 Tax=Burkholderia pseudomallei
           RepID=B1H9E3_BURPS
          Length = 485

 Score = 59.3 bits (142), Expect = 1e-07
 Identities = 27/59 (45%), Positives = 38/59 (64%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT 184
           +Q  +  I EL V+G+P     AF SD  DI+ VND M  +GW LN L+RP+++ +CVT
Sbjct: 360 MQAAVRAIPELRVLGKPTFCF-AFTSDAFDIYHVNDFMRQRGWRLNGLRRPDALQMCVT 417

[198][TOP]
>UniRef100_Q3JJF3 Pyridoxal-dependent decarboxylase conserved domain n=3
           Tax=Burkholderia pseudomallei RepID=Q3JJF3_BURP1
          Length = 473

 Score = 59.3 bits (142), Expect = 1e-07
 Identities = 27/59 (45%), Positives = 38/59 (64%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT 184
           +Q  +  I EL V+G+P     AF SD  DI+ VND M  +GW LN L+RP+++ +CVT
Sbjct: 348 MQAAVRAIPELRVLGKPTFCF-AFTSDAFDIYHVNDFMRQRGWRLNGLRRPDALQMCVT 405

[199][TOP]
>UniRef100_A8EMW8 Sphingosine-1-phosphate lyase n=1 Tax=Burkholderia pseudomallei
           406e RepID=A8EMW8_BURPS
          Length = 485

 Score = 59.3 bits (142), Expect = 1e-07
 Identities = 27/59 (45%), Positives = 38/59 (64%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT 184
           +Q  +  I EL V+G+P     AF SD  DI+ VND M  +GW LN L+RP+++ +CVT
Sbjct: 360 MQAAVRAIPELRVLGKPTFCF-AFTSDAFDIYHVNDFMRQRGWRLNGLRRPDALQMCVT 417

[200][TOP]
>UniRef100_Q4DT68 Sphingosine phosphate lyase-like protein, putative n=1
           Tax=Trypanosoma cruzi RepID=Q4DT68_TRYCR
          Length = 545

 Score = 58.9 bits (141), Expect = 2e-07
 Identities = 37/125 (29%), Positives = 67/125 (53%), Gaps = 13/125 (10%)
 Frame = +2

Query: 20  IEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLV- 196
           + ++  + ++G P  ++ AF S+ +DIF + D +S +GW LN LQ P+ +   VTL    
Sbjct: 416 LSKLPYITILGDPITSVFAFNSECIDIFILGDRLSERGWALNRLQFPSGLQFSVTLLQTN 475

Query: 197 -PAVDDFLKD-----------LKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELL 340
              VD F+KD           +KE+ +  +      +GG   IY +  ++ DR +V+++L
Sbjct: 476 EGVVDRFIKDVTSIGEEMYMAVKEAEKEHRVVKKDEAGG--SIYASQQRVSDRSIVKDIL 533

Query: 341 VDFMD 355
            +F+D
Sbjct: 534 REFLD 538

[201][TOP]
>UniRef100_UPI00016A690A sphingosine-1-phosphate lyase n=1 Tax=Burkholderia thailandensis
           TXDOH RepID=UPI00016A690A
          Length = 104

 Score = 58.5 bits (140), Expect = 2e-07
 Identities = 31/75 (41%), Positives = 45/75 (60%), Gaps = 2/75 (2%)
 Frame = +2

Query: 77  FGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT-LQLVPAV-DDFLKDLKESVETVK 250
           F SD  DI+ VND M  +GW  N LQ P+++H+CVT  Q  P V D F +DL E+V+  +
Sbjct: 1   FASDAFDIYHVNDFMRRQGWRFNGLQHPDALHMCVTGPQTQPGVADRFRQDLGEAVDYAR 60

Query: 251 KNPGPISGGLAPIYG 295
           ++  P     + +YG
Sbjct: 61  RHT-PARAQSSGVYG 74

[202][TOP]
>UniRef100_A7NLA0 Pyridoxal-dependent decarboxylase n=1 Tax=Roseiflexus castenholzii
           DSM 13941 RepID=A7NLA0_ROSCS
          Length = 474

 Score = 57.4 bits (137), Expect = 5e-07
 Identities = 32/116 (27%), Positives = 63/116 (54%), Gaps = 5/116 (4%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHL----NALQRPNSIHI 175
           +  G++ I  L+V+GRP M++ +F S  +++F++ D +  +GW+L    +  + P ++H+
Sbjct: 319 LMAGVDAIDGLYVLGRPAMSMFSFASQAINVFQLADALRRRGWYLQPQFSTPRSPRNLHV 378

Query: 176 CVTLQLVPAVDDFLKDLKESVETVKKNPGPISGGLA-PIYGAAGKMPDRGMVQELL 340
            +T  +   VD  + D+   VE V+  P PI   L   +  A  + P   +V+ L+
Sbjct: 379 SITYGVAHNVDALIADIAACVEEVRHMP-PIDLALVRSVVEALTQDPSPAVVEGLM 433

[203][TOP]
>UniRef100_A5US78 Pyridoxal-dependent decarboxylase n=1 Tax=Roseiflexus sp. RS-1
           RepID=A5US78_ROSS1
          Length = 474

 Score = 57.4 bits (137), Expect = 5e-07
 Identities = 32/112 (28%), Positives = 58/112 (51%), Gaps = 4/112 (3%)
 Frame = +2

Query: 17  GIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHL----NALQRPNSIHICVT 184
           GI  I  LFV+G+P M++ +F S+ +++F + D +  +GW+L    +    P ++H+ VT
Sbjct: 322 GINAIDGLFVLGQPAMSMFSFASNNINVFHLADALRRRGWYLQPQFSTPLSPRNLHVSVT 381

Query: 185 LQLVPAVDDFLKDLKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELL 340
             +   V+  L DL   VE V++ P      +  +  A  + P    + EL+
Sbjct: 382 YGVAHNVEALLADLAACVEEVRQAPPTDPTLIQTLVSAIARDPSPATIMELM 433

[204][TOP]
>UniRef100_Q4DXI1 Sphingosine phosphate lyase-like protein, putative n=1
           Tax=Trypanosoma cruzi RepID=Q4DXI1_TRYCR
          Length = 545

 Score = 55.5 bits (132), Expect = 2e-06
 Identities = 35/125 (28%), Positives = 65/125 (52%), Gaps = 13/125 (10%)
 Frame = +2

Query: 20  IEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLV- 196
           + ++  + ++G P  ++ AF S+ +DIF + D +  +GW LN LQ P+ +   VTL    
Sbjct: 416 LSKLPYITILGDPITSVFAFNSECIDIFLLGDRLRERGWALNRLQFPSGLQFSVTLLQTN 475

Query: 197 -PAVDDFLKD-----------LKESVETVKKNPGPISGGLAPIYGAAGKMPDRGMVQELL 340
               D F+KD           +KE+ +  +      +GG   IY +  ++ DR +V+++L
Sbjct: 476 EGVADRFIKDVTSIGEEMYIAVKEAEKEHRVVKKDEAGG--SIYASQQRVSDRSIVKDIL 533

Query: 341 VDFMD 355
            +F+D
Sbjct: 534 REFLD 538

[205][TOP]
>UniRef100_UPI0001B54B0B Pyridoxal-dependent decarboxylase n=1 Tax=Streptomyces sp. AA4
           RepID=UPI0001B54B0B
          Length = 471

 Score = 54.3 bits (129), Expect = 4e-06
 Identities = 35/92 (38%), Positives = 51/92 (55%), Gaps = 5/92 (5%)
 Frame = +2

Query: 8   IQKGIEEIAELFVVGRPDMTIVAF-GSDVLDIFEVNDIMSSKGWHLNAL----QRPNSIH 172
           I+ G+ EI  L V+G P  T+VAF GSD  D+F V D M ++GW++         P ++H
Sbjct: 307 IRAGVAEIPGLRVLGDPVSTLVAFTGSDGFDLFTVADEMKARGWYVQPQFAHGTSPLNLH 366

Query: 173 ICVTLQLVPAVDDFLKDLKESVETVKKNPGPI 268
           + VT     +  +FL DL  SVE  +   GP+
Sbjct: 367 LTVTAANHGSEPEFLADLAASVEAARAE-GPV 397

[206][TOP]
>UniRef100_UPI000186B165 hypothetical protein BRAFLDRAFT_112656 n=1 Tax=Branchiostoma
           floridae RepID=UPI000186B165
          Length = 166

 Score = 54.3 bits (129), Expect = 4e-06
 Identities = 28/76 (36%), Positives = 40/76 (52%)
 Frame = +2

Query: 29  IAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVD 208
           I  L ++G P MT  A GS  ++I  + D M SKGW +   Q PN +H  V        D
Sbjct: 9   IQGLCILGEPHMTAFAIGSRGINILALADEMESKGWRMERTQNPNGLHCTVMPSHTNVRD 68

Query: 209 DFLKDLKESVETVKKN 256
            F++DL  + E VK++
Sbjct: 69  KFVEDLTAAAEYVKED 84

[207][TOP]
>UniRef100_B8FMJ7 Pyridoxal-dependent decarboxylase n=1 Tax=Desulfatibacillum
           alkenivorans AK-01 RepID=B8FMJ7_DESAA
          Length = 478

 Score = 54.3 bits (129), Expect = 4e-06
 Identities = 33/101 (32%), Positives = 53/101 (52%), Gaps = 5/101 (4%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNAL----QRPNSI 169
           K I  GI +I  L ++ +P MT++AF SD +++F + D M+S+GW++         P  I
Sbjct: 317 KKITAGIPKIKGLRLLAQPQMTLIAFTSDSVNVFHIIDEMNSRGWYIQPALSYDNCPAHI 376

Query: 170 HICVTLQLVPAVDDFLKDLKESVETVKKNP-GPISGGLAPI 289
           H+ V+   V   D  L+DL+E        P G +   L P+
Sbjct: 377 HLSVSASNVGWEDKLLEDLEECTAIAAGMPEGELVTSLRPM 417

[208][TOP]
>UniRef100_B0ERR7 Putative uncharacterized protein n=1 Tax=Entamoeba dispar SAW760
           RepID=B0ERR7_ENTDI
          Length = 264

 Score = 54.3 bits (129), Expect = 4e-06
 Identities = 27/89 (30%), Positives = 49/89 (55%), Gaps = 6/89 (6%)
 Frame = +2

Query: 107 VNDIMSSK-GWHLNALQRPNSIHICVTLQLVPAVDDFLKDLKESVETVKKNP-GPISGGL 280
           V+D M+ +  W  N LQ P ++H CVT + +     F++DL ++++ ++K+P  P     
Sbjct: 174 VSDCMNKEFQWEFNTLQFPAAVHFCVTEKTIGCEKQFIEDLNKALDIIRKDPKNPKYNVW 233

Query: 281 APIYGAAGKMPD----RGMVQELLVDFMD 355
           AP+YG    +PD      MV +++  + D
Sbjct: 234 APVYGMTSSLPDIDTLEDMVSQVIAQYCD 262

[209][TOP]
>UniRef100_UPI00016A6907 sphingosine-1-phosphate lyase n=2 Tax=Burkholderia thailandensis
           RepID=UPI00016A6907
          Length = 104

 Score = 53.9 bits (128), Expect = 5e-06
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 2/62 (3%)
 Frame = +2

Query: 77  FGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVT-LQLVPAV-DDFLKDLKESVETVK 250
           F SD  DI+ VND M  +GW LN L+ P+++ +CVT  Q  P V D F +DL  +VE  +
Sbjct: 1   FTSDAFDIYHVNDFMRQRGWRLNGLRHPDALQMCVTEPQTRPGVADQFRRDLGAAVEHAR 60

Query: 251 KN 256
           ++
Sbjct: 61  RH 62

[210][TOP]
>UniRef100_Q966E7 Putative uncharacterized protein n=1 Tax=Caenorhabditis elegans
           RepID=Q966E7_CAEEL
          Length = 606

 Score = 53.9 bits (128), Expect = 5e-06
 Identities = 29/99 (29%), Positives = 54/99 (54%), Gaps = 3/99 (3%)
 Frame = +2

Query: 50  GRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVP--AVDDFLKD 223
           G  D+ +VAF +  ++++ + D+M  KGWH++ L  P +  + ++L +     +D FL+D
Sbjct: 439 GSADLCVVAFTTSEVNVYNLVDVMVQKGWHVDPLLSPAAARVPISLSMCEEGVLDHFLED 498

Query: 224 LKESVETVKK-NPGPISGGLAPIYGAAGKMPDRGMVQEL 337
           L+ ++  +K   P    G  A  Y    K+ D+ +V EL
Sbjct: 499 LEMAICNLKSMEPAEKLGTTASFYQMLQKVNDKTLVDEL 537

[211][TOP]
>UniRef100_C5KK71 Sphingosine-1-phosphate lyase, putative n=1 Tax=Perkinsus marinus
           ATCC 50983 RepID=C5KK71_9ALVE
          Length = 535

 Score = 53.9 bits (128), Expect = 5e-06
 Identities = 33/97 (34%), Positives = 52/97 (53%), Gaps = 6/97 (6%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAF----GSDVLDIFEVNDIMSSKGWHLNALQRPNSI 169
           K ++KGI +I  + V+GRP +++VA     G +  D  E     +   W+LN LQ P+ +
Sbjct: 427 KHLEKGINDIEGVRVLGRPSVSVVAITCTNGVNDYDFAEWLKNNTKTHWNLNMLQMPSGV 486

Query: 170 HICVTLQLVPAVDDFLKDLKESV--ETVKKNPGPISG 274
           HICVT      +D+ L D++  +  E  K + G  SG
Sbjct: 487 HICVTRLNAKKMDELLTDIEAGLKAEKAKLDAGVKSG 523

[212][TOP]
>UniRef100_C3YZ31 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3YZ31_BRAFL
          Length = 112

 Score = 53.9 bits (128), Expect = 5e-06
 Identities = 28/74 (37%), Positives = 38/74 (51%)
 Frame = +2

Query: 29  IAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGWHLNALQRPNSIHICVTLQLVPAVD 208
           I  L ++G P MT  A GS  ++I  + D M SKGW +   Q PN +H  V        D
Sbjct: 9   IQGLCILGEPHMTAFAIGSKGINILALADEMESKGWRMERTQNPNGLHCTVMPSHTNVRD 68

Query: 209 DFLKDLKESVETVK 250
            F++DL  + E VK
Sbjct: 69  KFVEDLTAAAEYVK 82

[213][TOP]
>UniRef100_C4EIP7 PLP-dependent enzyme, glutamate decarboxylase n=1
           Tax=Streptosporangium roseum DSM 43021
           RepID=C4EIP7_STRRS
          Length = 472

 Score = 53.1 bits (126), Expect = 9e-06
 Identities = 32/101 (31%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
 Frame = +2

Query: 2   KSIQKGIEEIAELFVVGRPDMTIVAFGSDVLDIFEVNDIMSSKGW----HLNALQRPNSI 169
           + +++GI  I  L V+G P+  +VAFGSD +++F ++D    +GW     L+    P +I
Sbjct: 311 RRLREGIAGIPGLRVLGDPESALVAFGSDEVNVFVLSDEARKRGWFLQPQLSYAGIPANI 370

Query: 170 HICVTLQLVPAVDDFLKDLKESVETVK-KNPGPISGGLAPI 289
           HI VT   +  V+  L+ + ES E  + + P  +  GL  +
Sbjct: 371 HITVTGVTLRGVEAMLEVIAESAEAARERGPAALPDGLVDL 411