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[1][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=B9DHL6_ARATH
Length = 402
Score = 372 bits (954), Expect = e-101
Identities = 180/180 (100%), Positives = 180/180 (100%)
Frame = -1
Query: 542 ARPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGK 363
ARPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGK
Sbjct: 181 ARPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGK 240
Query: 362 INSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP 183
INSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP
Sbjct: 241 INSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP 300
Query: 182 SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRS 3
SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRS
Sbjct: 301 SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRS 360
[2][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 372 bits (954), Expect = e-101
Identities = 180/180 (100%), Positives = 180/180 (100%)
Frame = -1
Query: 542 ARPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGK 363
ARPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGK
Sbjct: 371 ARPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGK 430
Query: 362 INSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP 183
INSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP
Sbjct: 431 INSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP 490
Query: 182 SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRS 3
SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRS
Sbjct: 491 SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRS 550
[3][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 328 bits (840), Expect = 2e-88
Identities = 152/180 (84%), Positives = 166/180 (92%)
Frame = -1
Query: 542 ARPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGK 363
+RP+ RDKKLQQEWVVPLKS+ED+QEKFKELC+GNLKSSPWSELDGLQPET+IINEQL K
Sbjct: 371 SRPRARDKKLQQEWVVPLKSVEDIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIK 430
Query: 362 INSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP 183
+NS GFLTINSQPSVNA +SDSP +GWGGP GYVYQKAYLEFFCSK+KLD +VEK KA P
Sbjct: 431 VNSKGFLTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP 490
Query: 182 SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRS 3
SITYMAVNK E WVSNT ++DVNAVTWGVFPAKE+IQPTIVDPASF VWKDEAFE WSRS
Sbjct: 491 SITYMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRS 550
[4][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 301 bits (770), Expect = 3e-80
Identities = 136/178 (76%), Positives = 154/178 (86%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKI 360
RP+ R KKL +EW PLKS+ED+ EKFK C+G LKSSPWSELDGLQPETKIINEQLGKI
Sbjct: 383 RPRARGKKLLEEWAAPLKSVEDIYEKFKVYCLGKLKSSPWSELDGLQPETKIINEQLGKI 442
Query: 359 NSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS 180
N GFLTINSQP+VN KSDSP++GWGGPGGYVYQKAYLEFFCSKDKL+ LV+K K+FP
Sbjct: 443 NLKGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYLEFFCSKDKLNALVDKCKSFPF 502
Query: 179 ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSR 6
+TY+AVNK +W+SN +DVNAVTWGVFP KE+IQPT+VDP SF VWKDEAFEIWSR
Sbjct: 503 VTYIAVNKGGSWISNVALTDVNAVTWGVFPGKEIIQPTVVDPTSFSVWKDEAFEIWSR 560
[5][TOP]
>UniRef100_A9P8D1 Putative uncharacterized protein n=1 Tax=Populus trichocarpa
RepID=A9P8D1_POPTR
Length = 224
Score = 301 bits (770), Expect = 3e-80
Identities = 136/178 (76%), Positives = 154/178 (86%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKI 360
RP+ R KKL +EW PLKS+ED+ EKFK C+G LKSSPWSELDGLQPETKIINEQLGKI
Sbjct: 2 RPRARGKKLLEEWAAPLKSVEDIYEKFKVYCLGKLKSSPWSELDGLQPETKIINEQLGKI 61
Query: 359 NSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS 180
N GFLTINSQP+VN KSDSP++GWGGPGGYVYQKAYLEFFCSKDKL+ LV+K K+FP
Sbjct: 62 NLKGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYLEFFCSKDKLNALVDKCKSFPF 121
Query: 179 ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSR 6
+TY+AVNK +W+SN +DVNAVTWGVFP KE+IQPT+VDP SF VWKDEAFEIWSR
Sbjct: 122 VTYIAVNKGGSWISNVALTDVNAVTWGVFPGKEIIQPTVVDPTSFSVWKDEAFEIWSR 179
[6][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 300 bits (768), Expect = 4e-80
Identities = 136/178 (76%), Positives = 156/178 (87%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKI 360
RP+ R KKL +EW PLKS+ED+ EKFK C+G LKSSPWSEL+GLQPETKIINEQLG+I
Sbjct: 386 RPRARGKKLFEEWASPLKSVEDIYEKFKVYCLGKLKSSPWSELEGLQPETKIINEQLGRI 445
Query: 359 NSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS 180
N GFLTINSQP+VNA KSDSP++GWGGPGGYVYQKAYLEFFCSK+KL+ LVE+ KAFP
Sbjct: 446 NLKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYLEFFCSKEKLNALVERCKAFPL 505
Query: 179 ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSR 6
+TYMAVN+ +W+SN +DVNAVTWGVFPAKE+IQPT+VDP SF VWKDEAFEIWSR
Sbjct: 506 VTYMAVNRGGSWISNVALTDVNAVTWGVFPAKEIIQPTVVDPTSFSVWKDEAFEIWSR 563
[7][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 299 bits (766), Expect = 8e-80
Identities = 137/178 (76%), Positives = 156/178 (87%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKI 360
RP+ RDKKLQ EWVVPLKSIEDVQE+F + C+G LKSSPWSELDGLQPE+KIINE LG I
Sbjct: 372 RPRARDKKLQDEWVVPLKSIEDVQERFIKFCLGKLKSSPWSELDGLQPESKIINELLGNI 431
Query: 359 NSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS 180
NS GFLTINSQP+VN KSDS ++GWGGPGGYVYQKAYLEFFCS++KL+ LV+K K PS
Sbjct: 432 NSKGFLTINSQPAVNGEKSDSLSVGWGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHPS 491
Query: 179 ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSR 6
+TYMAVNK W+SN G +VNAVTWGVFPA+E+IQPT+VDP+SF VWKDEAFEIWSR
Sbjct: 492 LTYMAVNKEGTWMSNVGPGEVNAVTWGVFPAREIIQPTVVDPSSFMVWKDEAFEIWSR 549
[8][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 296 bits (758), Expect = 6e-79
Identities = 136/178 (76%), Positives = 155/178 (87%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKI 360
RP+ RDKKLQ EWVVPLKSIEDVQE+F + C+G LKSSPWSELDGLQPE+KIINE LG I
Sbjct: 372 RPRARDKKLQDEWVVPLKSIEDVQERFIKFCLGKLKSSPWSELDGLQPESKIINELLGNI 431
Query: 359 NSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS 180
NS GFLTINSQP+VN KSDS ++GWGGPGGYVYQKAYLEFFCS++KL+ LV+K K S
Sbjct: 432 NSKGFLTINSQPAVNGEKSDSLSVGWGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHTS 491
Query: 179 ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSR 6
+TYMAVNK W+SN G +VNAVTWGVFPA+E+IQPT+VDP+SF VWKDEAFEIWSR
Sbjct: 492 LTYMAVNKEGTWMSNVGPGEVNAVTWGVFPAREIIQPTVVDPSSFMVWKDEAFEIWSR 549
[9][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 296 bits (758), Expect = 6e-79
Identities = 136/178 (76%), Positives = 155/178 (87%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKI 360
RP+ RDKKLQ EWVVPLKSIEDVQE+F + C+G LKSSPWSELDGLQPE+KIINE LG I
Sbjct: 365 RPRARDKKLQDEWVVPLKSIEDVQERFIKFCLGKLKSSPWSELDGLQPESKIINELLGNI 424
Query: 359 NSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS 180
NS GFLTINSQP+VN KSDS ++GWGGPGGYVYQKAYLEFFCS++KL+ LV+K K S
Sbjct: 425 NSKGFLTINSQPAVNGEKSDSLSVGWGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHTS 484
Query: 179 ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSR 6
+TYMAVNK W+SN G +VNAVTWGVFPA+E+IQPT+VDP+SF VWKDEAFEIWSR
Sbjct: 485 LTYMAVNKEGTWMSNVGPGEVNAVTWGVFPAREIIQPTVVDPSSFMVWKDEAFEIWSR 542
[10][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 295 bits (755), Expect = 1e-78
Identities = 134/178 (75%), Positives = 153/178 (85%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKI 360
RP+ RDKKL EWVVPL S ED+ EKFK+ C+G LK+SPWSELDGLQPETKIINEQLGKI
Sbjct: 387 RPRARDKKLHDEWVVPLSSAEDIFEKFKKHCLGKLKTSPWSELDGLQPETKIINEQLGKI 446
Query: 359 NSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS 180
N GFLTINSQP+VN KSDSP++GWGGPGGYVYQKAY+EFFCS DKL L+EK KA P
Sbjct: 447 NLKGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYIEFFCSTDKLQALLEKCKALPQ 506
Query: 179 ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSR 6
+TYMAVN+ +SN G++DVNAVTWGVFP K++IQPT+VDPASF VWKDEAFEIW+R
Sbjct: 507 LTYMAVNRGGTLLSNVGQNDVNAVTWGVFPGKQIIQPTVVDPASFSVWKDEAFEIWTR 564
[11][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 287 bits (735), Expect = 3e-76
Identities = 132/178 (74%), Positives = 150/178 (84%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKI 360
RP+GR KKLQ+EW VPLKS+ED+ E+F C G L SSPWSELDGLQPETKII++QL KI
Sbjct: 372 RPRGRGKKLQEEWAVPLKSVEDISERFTNFCQGKLTSSPWSELDGLQPETKIIDDQLVKI 431
Query: 359 NSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS 180
N GFLTINSQP+VN KSDSP +GWGGPGGYVYQKAYLEFFC+K+KLD L+EK KAFPS
Sbjct: 432 NQKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKAFPS 491
Query: 179 ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSR 6
+TY+AVNK SN + VNAVTWGVFP KE+IQPT+VDPASF VWKDEAFEIW+R
Sbjct: 492 LTYIAVNKDGESFSNIAPNAVNAVTWGVFPGKEIIQPTVVDPASFMVWKDEAFEIWTR 549
[12][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 285 bits (729), Expect = 1e-75
Identities = 131/178 (73%), Positives = 153/178 (85%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKI 360
RP+GR KKLQ+EW VPLKS++D+ E+F C G LKSSPWSELDGLQPET II++QL KI
Sbjct: 360 RPRGRGKKLQEEWAVPLKSVQDINERFVNFCEGKLKSSPWSELDGLQPETTIIDDQLVKI 419
Query: 359 NSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS 180
NS GFLTINSQP+VNA KS+SP++GWGGPGGYVYQKAY+EFFC+K+KL L+EKSKAFPS
Sbjct: 420 NSKGFLTINSQPAVNAEKSESPSVGWGGPGGYVYQKAYVEFFCAKEKLGQLIEKSKAFPS 479
Query: 179 ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSR 6
+TY+AVNK +SN + VNAVTWGVFP KE+IQPT+VD ASF VWKDEAFEIWSR
Sbjct: 480 LTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSR 537
[13][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 282 bits (722), Expect = 1e-74
Identities = 130/178 (73%), Positives = 148/178 (83%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKI 360
RP+GR KKLQ+EW VPLKS+ED+ E+F C G L SSPWSELDGLQPETKII++QL I
Sbjct: 372 RPRGRGKKLQEEWAVPLKSVEDISERFTNFCQGKLTSSPWSELDGLQPETKIIDDQLVNI 431
Query: 359 NSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS 180
N GFLTINSQP+VN KSDSP +GWGGPGGYVYQKAYLEFFC+K+KLD L+EK KAFPS
Sbjct: 432 NQKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKAFPS 491
Query: 179 ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSR 6
+TY+AVNK SN + VNAVTWGVFP KE+IQPT+VD ASF VWKDEAFEIW+R
Sbjct: 492 LTYIAVNKDGETFSNISPNAVNAVTWGVFPGKEIIQPTVVDHASFMVWKDEAFEIWTR 549
[14][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 281 bits (720), Expect = 2e-74
Identities = 129/178 (72%), Positives = 150/178 (84%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKI 360
RP+GR KKLQ+EW VP+KS+ED+ E+F C G L SSPWSELDGLQPETKII++QL KI
Sbjct: 372 RPRGRGKKLQEEWAVPVKSVEDINERFMNFCQGKLTSSPWSELDGLQPETKIIDDQLVKI 431
Query: 359 NSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS 180
N GFLTINSQP+VN +SDS ++GWGGPGGYVYQKAYLEFFCSK+KLD L+EKSKAFPS
Sbjct: 432 NQKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPS 491
Query: 179 ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSR 6
+TY+AVNK SN + VNAVTWGVFP KE++QPT+VD ASF VWKDEAFEIWS+
Sbjct: 492 LTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWKDEAFEIWSK 549
[15][TOP]
>UniRef100_A6N158 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Oryza sativa
Indica Group RepID=A6N158_ORYSI
Length = 237
Score = 281 bits (720), Expect = 2e-74
Identities = 129/178 (72%), Positives = 150/178 (84%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKI 360
RP+GR KKLQ+EW VP+KS+ED+ E+F C G L SSPWSELDGLQPETKII++QL KI
Sbjct: 15 RPRGRGKKLQEEWAVPVKSVEDINERFMNFCQGKLTSSPWSELDGLQPETKIIDDQLVKI 74
Query: 359 NSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS 180
N GFLTINSQP+VN +SDS ++GWGGPGGYVYQKAYLEFFCSK+KLD L+EKSKAFPS
Sbjct: 75 NQKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPS 134
Query: 179 ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSR 6
+TY+AVNK SN + VNAVTWGVFP KE++QPT+VD ASF VWKDEAFEIWS+
Sbjct: 135 LTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWKDEAFEIWSK 192
[16][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 281 bits (720), Expect = 2e-74
Identities = 129/178 (72%), Positives = 150/178 (84%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKI 360
RP+GR KKLQ+EW VP+KS+ED+ E+F C G L SSPWSELDGLQPETKII++QL KI
Sbjct: 372 RPRGRGKKLQEEWAVPVKSVEDINERFMNFCQGKLTSSPWSELDGLQPETKIIDDQLVKI 431
Query: 359 NSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS 180
N GFLTINSQP+VN +SDS ++GWGGPGGYVYQKAYLEFFCSK+KLD L+EKSKAFPS
Sbjct: 432 NQKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPS 491
Query: 179 ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSR 6
+TY+AVNK SN + VNAVTWGVFP KE++QPT+VD ASF VWKDEAFEIWS+
Sbjct: 492 LTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWKDEAFEIWSK 549
[17][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 262 bits (669), Expect = 1e-68
Identities = 121/178 (67%), Positives = 143/178 (80%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKI 360
R + R KK+ +EWVVPL SI D+QEKF C+G LKS+PWSELDGLQPET INE+L ++
Sbjct: 372 RRRSRSKKILEEWVVPLSSIVDIQEKFANFCVGKLKSNPWSELDGLQPETVKINEKLEQL 431
Query: 359 NSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS 180
N GFLTINSQP+VN KSDSP+IGWGG GYVYQKAY+EFFCS +KL+ LVEK+K P
Sbjct: 432 NRKGFLTINSQPAVNGEKSDSPSIGWGGAAGYVYQKAYVEFFCSPEKLNELVEKAKNLPF 491
Query: 179 ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSR 6
+TY+AVNK +N G +DVNAVTWGVFPAKEVIQPT+VDP SF VWKDEAF+ W +
Sbjct: 492 VTYIAVNKKGATAANIGPTDVNAVTWGVFPAKEVIQPTVVDPVSFMVWKDEAFQAWEQ 549
[18][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 251 bits (642), Expect = 2e-65
Identities = 117/178 (65%), Positives = 137/178 (76%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKI 360
R K R KKLQ+EW VPL S EDV F + C G L + PWSEL+GLQPET INE+L +
Sbjct: 372 RKKTRSKKLQKEWAVPLNSSEDVNAIFAKYCQGTLSTHPWSELEGLQPETVQINEKLVAL 431
Query: 359 NSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS 180
N GFLTINSQP+VN KSDSP++GWGGPGGYVYQKAY+EFFCS +KL ++EK+K PS
Sbjct: 432 NQGGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYVEFFCSPEKLQAVIEKAKTSPS 491
Query: 179 ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSR 6
+TY+AVN SN G + VNAVTWGVFPAKEVIQPT+VDP SF VWKDEAF+ W +
Sbjct: 492 LTYIAVNAKGETKSNVGPTSVNAVTWGVFPAKEVIQPTVVDPVSFMVWKDEAFQAWDQ 549
[19][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 249 bits (637), Expect = 7e-65
Identities = 115/176 (65%), Positives = 139/176 (78%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKI 360
R K R KKLQ+EW VPL S EDV + F + C G L + PWSEL+GLQPET IN++L +
Sbjct: 372 RKKTRSKKLQKEWAVPLNSCEDVNQIFAKYCQGTLSTHPWSELEGLQPETSQINDKLVAL 431
Query: 359 NSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS 180
N+ GFLTINSQP+VN KSDSP++GWGGPGGYVYQKAY+EFFCS +KL ++EK+K+ PS
Sbjct: 432 NTQGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYVEFFCSPEKLQAVIEKAKSNPS 491
Query: 179 ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
+T++AVN SN G + VNAVTWGVFPAKEVIQPT+VDP SF VWKDEAF+ W
Sbjct: 492 LTFIAVNAKGETQSNIGPNCVNAVTWGVFPAKEVIQPTVVDPVSFMVWKDEAFQTW 547
[20][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 181 bits (460), Expect = 2e-44
Identities = 91/176 (51%), Positives = 112/176 (63%), Gaps = 1/176 (0%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDG-LQPETKIINEQLGKIN 357
+ R +K + W S++DV++ F + G + PW+ELDG L E I E L +N
Sbjct: 374 EARREKARAAWGAAPASVDDVKQVFVKYIKGEVSLLPWAELDGGLTAEAAAIREPLAALN 433
Query: 356 SNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSI 177
+NG+LTINSQP VN SD GWGGPGGYVY KAY+EFFCS + TL K A PSI
Sbjct: 434 ANGYLTINSQPRVNGVASDDAVHGWGGPGGYVYGKAYVEFFCSPEAWATLRAKLDAAPSI 493
Query: 176 TYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWS 9
TY+A + + N VNAVTWGVFP KEVIQPT+V SF VWKDEAFE+W+
Sbjct: 494 TYLATTAAGSPAGNMAPDAVNAVTWGVFPGKEVIQPTVVCAPSFAVWKDEAFELWT 549
[21][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 172 bits (435), Expect = 2e-41
Identities = 85/170 (50%), Positives = 115/170 (67%)
Frame = -1
Query: 524 DKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGF 345
+++ ++ W P ++DV+ F++ C G +K+ PWSE + ET +I+++L K+N GF
Sbjct: 386 NEEAKEMWGAPT-CLDDVKTLFQQFCAGQVKALPWSETP-VARETSVISDKLAKMNQLGF 443
Query: 344 LTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMA 165
LTINSQP+V+ A+SD GWG GYVYQKAYLEFF S + LD L+ + +A P ITY A
Sbjct: 444 LTINSQPAVDGARSDDKVHGWGPKNGYVYQKAYLEFFVSPEDLDALIARIEADPQITYHA 503
Query: 164 VNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
VN + +NT NAVTWGVFP E+IQPTIV+ SF WKDEA+EI
Sbjct: 504 VNSQGDMRTNTNSEAPNAVTWGVFPHCEIIQPTIVESISFLAWKDEAYEI 553
[22][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 170 bits (431), Expect = 5e-41
Identities = 85/186 (45%), Positives = 117/186 (62%), Gaps = 8/186 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGN-------LKSSPWSELDGLQPETKII 381
R K + +++ + W L ++DV E FK G + S PW++ + L ET I
Sbjct: 354 RSKAKKEQMLKMWGQQLNDVQDVFEVFKCYISGEKNENGVKVTSLPWND-EELALETSFI 412
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
E+L NSNG L+INSQPSVNAA S P +GWGG GGY+YQKAYLEFF S + + L++
Sbjct: 413 KEKLIHFNSNGILSINSQPSVNAASSTDPLLGWGGEGGYIYQKAYLEFFASPEVVYILLQ 472
Query: 200 KSKAFPSITYMAVNKSENW-VSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
+ K +P + Y VN + ++N AVTWGVFP +E++QPT+VDP SFK+WKDEA
Sbjct: 473 ELKNYPQVNYHVVNNHDTVDITNCDSQTPVAVTWGVFPGREIVQPTVVDPISFKIWKDEA 532
Query: 23 FEIWSR 6
F +W +
Sbjct: 533 FSLWEQ 538
[23][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 169 bits (427), Expect = 2e-40
Identities = 82/185 (44%), Positives = 116/185 (62%), Gaps = 8/185 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGN-------LKSSPWSELDGLQPETKII 381
+P + ++L W L ++DV + F G ++ PW++ D L ET I
Sbjct: 398 KPNAKKEELLDMWGHELTCLQDVCDVFTNYITGKESKNGKKVRKIPWND-DDLAAETSFI 456
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
N++L +INS G LTINSQP+VNAA S P +GWG PGGYV+QKAYLEFF S++ + L +
Sbjct: 457 NDKLARINSRGVLTINSQPNVNAAPSTDPVVGWGTPGGYVFQKAYLEFFTSRENVQALFK 516
Query: 200 KSKAFPSITYMAVN-KSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
+P++ Y + + ++ +N + AVTWGVFP KE+IQPT+VDP SFK WKDEA
Sbjct: 517 VLPKYPNVNYHIIKFEGDDDYTNCDQQQPIAVTWGVFPGKEIIQPTVVDPVSFKFWKDEA 576
Query: 23 FEIWS 9
F +W+
Sbjct: 577 FTLWT 581
[24][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 167 bits (424), Expect = 3e-40
Identities = 88/166 (53%), Positives = 105/166 (63%), Gaps = 3/166 (1%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQP---ETKIINEQLGKINSNGFLTIN 333
W P S D+ F C G+L PWS QP ET +I EQL K+N G+LTIN
Sbjct: 381 WGHPTTS-SDLHALFARFCRGDLAKLPWST----QPPASETSLIIEQLAKMNELGYLTIN 435
Query: 332 SQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKS 153
SQP+V+ +SD GWG PGGYVYQKAYLEFF S D L L+ + + P ITY AVNK
Sbjct: 436 SQPAVDGVRSDDKVHGWGPPGGYVYQKAYLEFFVSPDLLSPLIRRIEKDPRITYYAVNKQ 495
Query: 152 ENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
+ +NT NAVTWGVFP KE++QPTIV+ SF WKDEAFE+
Sbjct: 496 GDLRTNTHSESPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFEL 541
[25][TOP]
>UniRef100_A8Q9P3 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8Q9P3_MALGO
Length = 515
Score = 167 bits (423), Expect = 4e-40
Identities = 84/160 (52%), Positives = 102/160 (63%)
Frame = -1
Query: 485 SIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAK 306
+I+D+Q F C G L PWS+ L ET +INE L +N GF TINSQP+V+ A+
Sbjct: 307 TIQDLQSLFARFCTGELACLPWSDAP-LAKETSVINEPLRALNERGFFTINSQPAVDGAR 365
Query: 305 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 126
SD P GWG GYVYQKAYLEFF S +LD L+ + A P ITY AVN + +NT
Sbjct: 366 SDDPVHGWGPKHGYVYQKAYLEFFVSPQQLDELIARFDAHPQITYHAVNAQGDMRTNTTS 425
Query: 125 SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSR 6
NAVTWG FP E++QPTIV+ SF WKDEA+EI R
Sbjct: 426 DAPNAVTWGCFPHCEILQPTIVESMSFLAWKDEAYEIGRR 465
[26][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 164 bits (416), Expect = 3e-39
Identities = 89/178 (50%), Positives = 110/178 (61%), Gaps = 8/178 (4%)
Frame = -1
Query: 518 KLQQEWVVPLKSIEDVQEKFKELCIGN-------LKSSPWSELDGLQPETKIINEQLGKI 360
+L + W L+S+EDV E F G + + PWS D L ET I + L I
Sbjct: 400 ELLKMWGEKLESVEDVYEIFTCFVSGERNKYGYKVDALPWSN-DALALETLFIKKSLEYI 458
Query: 359 NSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS 180
NS G LTINSQP+VNA S GWGGP GYVYQKAYLEFF S ++ TL+E FP
Sbjct: 459 NSKGILTINSQPNVNALPSTHEVFGWGGPNGYVYQKAYLEFFISAERFKTLLEVLPNFPM 518
Query: 179 ITYMAVNKSENW-VSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWS 9
I Y A++ SE+ VSN+ AVTWGVFP +E++QPT+VDP SF WKDEAF +W+
Sbjct: 519 INYHALDLSESINVSNSDHHQPIAVTWGVFPGREILQPTVVDPTSFSYWKDEAFALWT 576
[27][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 161 bits (408), Expect = 2e-38
Identities = 80/157 (50%), Positives = 100/157 (63%)
Frame = -1
Query: 485 SIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAK 306
S D+ F C L + PWS+ Q ET +I EQL +N GFLTINSQP+VN+A+
Sbjct: 382 SFADIASLFSRFCTKKLSALPWSDQAPSQ-ETSVIAEQLATMNEFGFLTINSQPAVNSAR 440
Query: 305 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 126
SD P GWG GYVYQKAYLEFF + L+ L+ + +ITY +NK + +NT
Sbjct: 441 SDDPVFGWGPSNGYVYQKAYLEFFVNPTLLNLLLTHIERDSNITYYVINKRGDLRTNTHS 500
Query: 125 SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
NAVTWGVFP KE++QPTIV+ SF WKDEAFE+
Sbjct: 501 DGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFEL 537
[28][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 160 bits (404), Expect = 7e-38
Identities = 80/184 (43%), Positives = 107/184 (58%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSS-------PWSELDGLQPETKII 381
+ K + L Q W L S E V E F G S PW++ D L PET ++
Sbjct: 409 KSKSPKEALLQMWGEELMSEESVYEVFTNYITGQTNRSGHKVMCLPWND-DPLAPETNLL 467
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
++L K+N G LTINSQP++N S +GWG GGYV+QKAYLEFF S + + L++
Sbjct: 468 KDELEKVNRRGVLTINSQPNINGKASSDAIVGWGPAGGYVFQKAYLEFFTSSENVTALLQ 527
Query: 200 KSKAF-PSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
K + P + Y VN ++N + NAVTWG+FP +E+IQPT+VDP SF WKDEA
Sbjct: 528 VLKKYEPRVNYQIVNVQGRNITNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEA 587
Query: 23 FEIW 12
F +W
Sbjct: 588 FALW 591
[29][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 160 bits (404), Expect = 7e-38
Identities = 81/159 (50%), Positives = 101/159 (63%)
Frame = -1
Query: 488 KSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAA 309
+S +DV F C GN+K PW++ L E++ I EQL +N NGFLTINSQP++N
Sbjct: 398 QSEQDVYNVFASYCSGNIKRLPWND-SPLSLESENIKEQLVFLNKNGFLTINSQPAINGL 456
Query: 308 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 129
S GWGG G VY+KAY+EFF S + L+E K P ITY AVN+ + S T
Sbjct: 457 PSTDKQHGWGGKNGIVYKKAYIEFFASPENTLKLIEYFKKCPMITYHAVNRKGD--SKTN 514
Query: 128 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
NAVTWG+FP KE+IQPT+VD SF VWKDEAF +W
Sbjct: 515 TKGTNAVTWGIFPGKEIIQPTVVDHNSFMVWKDEAFALW 553
[30][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 160 bits (404), Expect = 7e-38
Identities = 84/169 (49%), Positives = 105/169 (62%), Gaps = 3/169 (1%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQP 324
W P ++E+V F + C G L + PWS+ ET II QL K+N GFLTINSQP
Sbjct: 337 WGYPT-TLEEVSVLFAKFCKGELDALPWSD-SAPSKETSIIATQLAKMNELGFLTINSQP 394
Query: 323 SVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENW 144
+VN A+SD GWG GYVYQKAYLEFF L L++ + +ITY +NK +
Sbjct: 395 AVNGARSDDKIFGWGPSNGYVYQKAYLEFFVDPALLQLLLKHLERDTNITYHVINKRGDL 454
Query: 143 VSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI---WSR 6
+NT NAVTWGVFP KE+IQPTIV+ SF WKDEA+E+ W+R
Sbjct: 455 QTNTHSEGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAYELGAQWAR 503
[31][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 157 bits (396), Expect = 6e-37
Identities = 84/184 (45%), Positives = 111/184 (60%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGN-------LKSSPWSELDGLQPETKII 381
+ K +++ + W L IEDV F+ G +KS P ++ D LQPET ++
Sbjct: 387 KSKESEEERLKMWGEKLDCIEDVYHVFQCYLSGKKNKWGYKVKSLPLND-DELQPETSLL 445
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
++QL +IN +GFLT NSQP+VNAA S GWGG GGY+YQKAYLEFF K +D L+E
Sbjct: 446 SDQLYRINGHGFLTTNSQPAVNAALSTDERFGWGGAGGYIYQKAYLEFFMHKKNVDFLLE 505
Query: 200 KSKAFPSITYMAVNKSENW-VSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
P + Y ++ + +N AVTWGVFP KE+IQPT+VDP SF WKDEA
Sbjct: 506 VLNDNPRVNYHIIDSHGCYDKTNADRYSPIAVTWGVFPGKEIIQPTVVDPISFNFWKDEA 565
Query: 23 FEIW 12
F +W
Sbjct: 566 FSLW 569
[32][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 155 bits (391), Expect = 2e-36
Identities = 79/184 (42%), Positives = 107/184 (58%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGN-------LKSSPWSELDGLQPETKII 381
+ K ++L + W L S E V E F G + PW++ D L PET ++
Sbjct: 403 KSKSPREELLKMWGQELNSEESVFEVFTYYISGEPNPNGHKVNCLPWND-DPLAPETNLL 461
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
+L K+N G LTINSQP+VN S P +GWG GYV+QKAYLEFF S + + L++
Sbjct: 462 KNELQKVNKRGILTINSQPNVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEMVSALIK 521
Query: 200 KSKAF-PSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
K + P + Y VN ++N + NAVTWG+FP +E+IQPT+VDP SF WKDEA
Sbjct: 522 VLKRYEPRVNYHIVNVHGQNITNAADLQPNAVTWGIFPGREIIQPTVVDPVSFVYWKDEA 581
Query: 23 FEIW 12
F +W
Sbjct: 582 FALW 585
[33][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 155 bits (391), Expect = 2e-36
Identities = 82/163 (50%), Positives = 101/163 (61%), Gaps = 1/163 (0%)
Frame = -1
Query: 494 PLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVN 315
P KS EDV E F G + PW E LQPE+ +I +L +N GFLTINSQPSVN
Sbjct: 419 PTKS-EDVYEVFALYIEGKIPHIPWCEAT-LQPESFLIQTKLAALNRAGFLTINSQPSVN 476
Query: 314 AAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSN 135
AA S + GWGGPGGY+YQKAY E FCS + + LV K S+ AVN + N +
Sbjct: 477 AALSTHESFGWGGPGGYIYQKAYCECFCSPENMRCLVNMVKQNQSMNVYAVNNAGNCIQE 536
Query: 134 TGE-SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWS 9
E V A+TWGVFP +E++QPTI DP F VW +EAF +W+
Sbjct: 537 GTELGGVTALTWGVFPNREILQPTIFDPRIFLVWAEEAFSLWT 579
[34][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 155 bits (391), Expect = 2e-36
Identities = 80/173 (46%), Positives = 105/173 (60%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ + W P KSI+D+ E F ++S PWSE + E II L ++N
Sbjct: 366 KGSNEQNIKLWGQP-KSIKDIAELFVSYLENGIESLPWSEAP-ISSEADIIKSDLIELNR 423
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
GFLTINSQP+V+ KS P GWG GYVYQKAYLE + D + LV + + P +T
Sbjct: 424 RGFLTINSQPAVDGVKSSDPVYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQHDPDLT 483
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y AV K+ + +N NAVTWGVFP KE++QPTIV+ SF WKDEAF +
Sbjct: 484 YYAVKKTGDLQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRL 536
[35][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
RepID=A8PV87_BRUMA
Length = 656
Score = 154 bits (388), Expect = 5e-36
Identities = 83/182 (45%), Positives = 112/182 (61%), Gaps = 10/182 (5%)
Frame = -1
Query: 527 RDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSS-------PWSEL-DGLQPETKIINEQ 372
RD++L+ + L+++ D+Q+ F N+ + PW+E DG++ ET +I +Q
Sbjct: 427 RDEQLRM-YGERLETLADIQKVFVNFITQNINENGVKVSQLPWNEQHDGIRAETSLIKDQ 485
Query: 371 LGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSK 192
L NSNGFLTINSQPS+N A S P +GWG PGGY YQKAYLEFF S+ + L
Sbjct: 486 LLWCNSNGFLTINSQPSINGAPSTDPFVGWGKPGGYCYQKAYLEFFTSQANAEVLWSLLP 545
Query: 191 AFPSITYMAVNKSE--NWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFE 18
++ + VN +W +NT + AVTWGVFP E+ QPT+VDP SF+VWKDEAF
Sbjct: 546 SYSRLNCHIVNHDATIDW-TNTETTMPIAVTWGVFPGSEIAQPTVVDPLSFRVWKDEAFS 604
Query: 17 IW 12
W
Sbjct: 605 AW 606
[36][TOP]
>UniRef100_Q8MQE7 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis elegans
RepID=Q8MQE7_CAEEL
Length = 642
Score = 153 bits (387), Expect = 7e-36
Identities = 74/142 (52%), Positives = 99/142 (69%), Gaps = 4/142 (2%)
Frame = -1
Query: 425 PWSELD-GLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKA 249
PW+E + G+QPET +I+EQL N NG LT+NSQPSVN A S P +GWG PGGY YQKA
Sbjct: 447 PWTEAETGVQPETSLISEQLVWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKA 506
Query: 248 YLEFFCSKDKLDTLVE-KSKAFP-SITYMAVNKSENW-VSNTGESDVNAVTWGVFPAKEV 78
YLE F + + D L++ + FP + Y A+NK + +N+ E+ AVTWGVFP E+
Sbjct: 507 YLECFMTAELSDKLIQIIEREFPVRVNYHAINKDSTFDKTNSEETTPIAVTWGVFPGSEI 566
Query: 77 IQPTIVDPASFKVWKDEAFEIW 12
QPT+VDP SF+ W+DEA+++W
Sbjct: 567 AQPTVVDPLSFRAWRDEAYQMW 588
[37][TOP]
>UniRef100_Q17693 Probable methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis
elegans RepID=MTHR_CAEEL
Length = 663
Score = 153 bits (387), Expect = 7e-36
Identities = 74/142 (52%), Positives = 99/142 (69%), Gaps = 4/142 (2%)
Frame = -1
Query: 425 PWSELD-GLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKA 249
PW+E + G+QPET +I+EQL N NG LT+NSQPSVN A S P +GWG PGGY YQKA
Sbjct: 468 PWTEAETGVQPETSLISEQLVWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKA 527
Query: 248 YLEFFCSKDKLDTLVE-KSKAFP-SITYMAVNKSENW-VSNTGESDVNAVTWGVFPAKEV 78
YLE F + + D L++ + FP + Y A+NK + +N+ E+ AVTWGVFP E+
Sbjct: 528 YLECFMTAELSDKLIQIIEREFPVRVNYHAINKDSTFDKTNSEETTPIAVTWGVFPGSEI 587
Query: 77 IQPTIVDPASFKVWKDEAFEIW 12
QPT+VDP SF+ W+DEA+++W
Sbjct: 588 AQPTVVDPLSFRAWRDEAYQMW 609
[38][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 152 bits (385), Expect = 1e-35
Identities = 83/185 (44%), Positives = 106/185 (57%), Gaps = 9/185 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIG-------NLKSSPWSELDGLQPETKII 381
R + KL+ W L S DV + FK G + +PW++ DGL PET ++
Sbjct: 382 RSRTAKDKLRSLWGKELTSEADVWKVFKHFITGAVNENGVKVTETPWND-DGLSPETNVL 440
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTL-V 204
+ L + N G LTINSQP+VNA S P GWG GGY+ QKAYLEFF +K + L
Sbjct: 441 SSTLSRYNELGVLTINSQPNVNAVPSTHPIYGWGDKGGYISQKAYLEFFINKHYAEALKT 500
Query: 203 EKSKAFPSITYMAVNK-SENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDE 27
K P + Y +NK +N S+ NAVTWG+F KE+IQPT+VDP SF VWKDE
Sbjct: 501 VLPKYHPRVNYHMINKCGTTDHTNADRSNPNAVTWGIFAGKEIIQPTVVDPVSFIVWKDE 560
Query: 26 AFEIW 12
AF +W
Sbjct: 561 AFGLW 565
[39][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 152 bits (385), Expect = 1e-35
Identities = 78/184 (42%), Positives = 107/184 (58%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSS-------PWSELDGLQPETKII 381
+ K ++L + W L S E V E F G + PW++ D L PET ++
Sbjct: 403 KSKSPREELLKMWGQELSSEESVFEVFTYYISGEPNPNGHKVTCLPWND-DPLAPETNLL 461
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
+L K+N G LTINSQP+VN S P +GWG GYV+QKAYLEFF S + + L++
Sbjct: 462 KSELQKVNKRGILTINSQPNVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEMVTALIK 521
Query: 200 KSKAF-PSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
K + P + Y VN ++N + +AVTWG+FP +E+IQPT+VDP SF WKDEA
Sbjct: 522 VLKRYEPRVNYHIVNVHGQNITNAADLQPSAVTWGIFPGREIIQPTVVDPVSFMYWKDEA 581
Query: 23 FEIW 12
F +W
Sbjct: 582 FALW 585
[40][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 152 bits (384), Expect = 1e-35
Identities = 80/190 (42%), Positives = 109/190 (57%), Gaps = 14/190 (7%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKF-------------KELCIGNLKSSPWSELDGLQ 399
+ K + L Q W L S E V E F K LC+ PW++ + L
Sbjct: 413 KSKSSKEALLQMWGEELLSEESVFEVFTCYITAQTNRSGQKVLCL------PWND-EPLA 465
Query: 398 PETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDK 219
PET ++ ++L K+N G LTINSQP++N S P +GWG GGYVYQKAYLEFF S +
Sbjct: 466 PETNLLKDELEKVNRRGVLTINSQPNINGKPSTDPIVGWGPAGGYVYQKAYLEFFTSSEN 525
Query: 218 LDTLVEKSKAF-PSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFK 42
+ L++ K + P + Y VN ++N + NAVTWG+F +E++QPT+VDP SF
Sbjct: 526 VTALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPNAVTWGIFAGREIVQPTVVDPVSFM 585
Query: 41 VWKDEAFEIW 12
WKDEAF +W
Sbjct: 586 SWKDEAFALW 595
[41][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 152 bits (384), Expect = 1e-35
Identities = 80/190 (42%), Positives = 109/190 (57%), Gaps = 14/190 (7%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKF-------------KELCIGNLKSSPWSELDGLQ 399
+ K + L Q W L S E V E F K LC+ PW++ + L
Sbjct: 413 KSKSSKEALLQMWGEELLSEESVFEVFTCYITAQTNRSGQKVLCL------PWND-EPLA 465
Query: 398 PETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDK 219
PET ++ ++L K+N G LTINSQP++N S P +GWG GGYVYQKAYLEFF S +
Sbjct: 466 PETNLLKDELEKVNRRGVLTINSQPNINGKPSTDPIVGWGPAGGYVYQKAYLEFFTSSEN 525
Query: 218 LDTLVEKSKAF-PSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFK 42
+ L++ K + P + Y VN ++N + NAVTWG+F +E++QPT+VDP SF
Sbjct: 526 VTALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPNAVTWGIFAGREIVQPTVVDPVSFM 585
Query: 41 VWKDEAFEIW 12
WKDEAF +W
Sbjct: 586 SWKDEAFALW 595
[42][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 152 bits (383), Expect = 2e-35
Identities = 79/173 (45%), Positives = 103/173 (59%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ + W PL SI+D+ + F G L+S PWSE + E I L +N
Sbjct: 366 KGTNEQNIKLWGTPL-SIKDLSDLFVRYMEGKLESLPWSE-QPITGEATSIRNDLIDLNR 423
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
GFLTINSQP+VN AKS P GWG GYVYQKAYLE S + + ++ + + P T
Sbjct: 424 RGFLTINSQPAVNGAKSSDPTFGWGPRNGYVYQKAYLEVLVSPEYIAEIITRIERDPEFT 483
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y AVNK + +N NAVTWGVFP KE++QPTIV+ SF WKDE + +
Sbjct: 484 YYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRL 536
[43][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 151 bits (382), Expect = 3e-35
Identities = 77/184 (41%), Positives = 111/184 (60%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGN-------LKSSPWSELDGLQPETKII 381
+ K ++L + W L S E V E F+ G + PW++ + L ET ++
Sbjct: 449 KSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLM 507
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
E+L ++N G LTINSQP++NA S P +GWG GGYV+QKAYLEFF S++ ++ L++
Sbjct: 508 KEELLRVNRLGILTINSQPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQ 567
Query: 200 KSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
K + + Y V+ ++N E NAVTWG+FP +E+IQPT+VDP SF WKDEA
Sbjct: 568 VLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEA 627
Query: 23 FEIW 12
F +W
Sbjct: 628 FALW 631
[44][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 151 bits (382), Expect = 3e-35
Identities = 77/184 (41%), Positives = 111/184 (60%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGN-------LKSSPWSELDGLQPETKII 381
+ K ++L + W L S E V E F+ G + PW++ + L ET ++
Sbjct: 449 KSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLM 507
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
E+L ++N G LTINSQP++NA S P +GWG GGYV+QKAYLEFF S++ ++ L++
Sbjct: 508 KEELLRVNRLGILTINSQPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQ 567
Query: 200 KSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
K + + Y V+ ++N E NAVTWG+FP +E+IQPT+VDP SF WKDEA
Sbjct: 568 VLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEA 627
Query: 23 FEIW 12
F +W
Sbjct: 628 FALW 631
[45][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 151 bits (382), Expect = 3e-35
Identities = 77/173 (44%), Positives = 109/173 (63%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ + W P KS++D+ + F G L PWSE + E+ II + L +N+
Sbjct: 366 KGTNEQNIKLWGEP-KSVKDLSDIFIRFLEGKLDRLPWSE-SAITQESDIIKDDLIALNN 423
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
GFLTINSQP++N AKS P GWG GYVYQKAYLE S +D ++ + + P +T
Sbjct: 424 RGFLTINSQPAINGAKSSHPIYGWGPKNGYVYQKAYLELLISPTLIDEVIRRIETNPDLT 483
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y +NK+ +N+ ++ NAVTWG+F +KEVIQPTIV+ SF WKDEA+ +
Sbjct: 484 YHCINKNGELRTNSSDTP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRL 535
[46][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 151 bits (382), Expect = 3e-35
Identities = 77/184 (41%), Positives = 111/184 (60%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGN-------LKSSPWSELDGLQPETKII 381
+ K ++L + W L S E V E F+ G + PW++ + L ET ++
Sbjct: 408 KSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLM 466
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
E+L ++N G LTINSQP++NA S P +GWG GGYV+QKAYLEFF S++ ++ L++
Sbjct: 467 KEELLRVNRLGILTINSQPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQ 526
Query: 200 KSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
K + + Y V+ ++N E NAVTWG+FP +E+IQPT+VDP SF WKDEA
Sbjct: 527 VLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEA 586
Query: 23 FEIW 12
F +W
Sbjct: 587 FALW 590
[47][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 151 bits (381), Expect = 3e-35
Identities = 78/173 (45%), Positives = 101/173 (58%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ + W P+ I D+ + F G L S PWSE + E I L +N
Sbjct: 366 KGTNEQNVKLWGSPM-CIRDLSDLFVRYMEGKLDSLPWSE-QAITTEAGPIRSDLIDLNR 423
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
GFLTINSQP+VN AKS P GWG GYVYQKAYLE F S + + ++ + + P T
Sbjct: 424 RGFLTINSQPAVNGAKSSDPVFGWGPRNGYVYQKAYLEVFVSPEYISEIITRLERDPEFT 483
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y AVNK + +N NAVTWGVFP KE++QPTIV+ SF WKDE + +
Sbjct: 484 YYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRL 536
[48][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 150 bits (380), Expect = 4e-35
Identities = 77/177 (43%), Positives = 105/177 (59%), Gaps = 8/177 (4%)
Frame = -1
Query: 518 KLQQEWVVPLKSIEDVQEKFKELCIGNLKSS-------PWSELDGLQPETKIINEQLGKI 360
+L + W L S E V E F G + PW++ + L ET ++ E+L K+
Sbjct: 410 ELLKMWGEELTSEESVFEVFTYYLSGEPNQNGYKVTCLPWND-EPLAAETSLMKEELLKV 468
Query: 359 NSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP- 183
N G LTINSQP++N S P +GWG GGYV+QKAYLEFF S + ++ L++ K +
Sbjct: 469 NQRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSETVEALLQVLKKYEL 528
Query: 182 SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
+ Y VN ++N E NAVTWG+FP +E+IQPT+VDP SF WKDEAF +W
Sbjct: 529 RVNYHIVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALW 585
[49][TOP]
>UniRef100_UPI0000123E6B Hypothetical protein CBG12960 n=1 Tax=Caenorhabditis briggsae AF16
RepID=UPI0000123E6B
Length = 662
Score = 150 bits (380), Expect = 4e-35
Identities = 78/171 (45%), Positives = 110/171 (64%), Gaps = 11/171 (6%)
Frame = -1
Query: 491 LKSIEDVQEKFKELCIGNLKSS-------PWSELD-GLQPETKIINEQLGKINSNGFLTI 336
++SIEDV+ F S PW+E + G+QPET +I+EQL N NG LT+
Sbjct: 440 IESIEDVKRVFINYITQTPNVSGKKVTVLPWTEAETGVQPETSLISEQLVWCNENGILTV 499
Query: 335 NSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE-KSKAFP-SITYMAV 162
NSQPSVN A S P +GWG PGGY YQKAYLE F + + + L++ + +P + Y A+
Sbjct: 500 NSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSEKLIDIIEREYPVRVNYHAI 559
Query: 161 NKSENW-VSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
+K ++ +N+ E+ AVTWGVFP E+ QPT+VDP SF+ W+DEA+++W
Sbjct: 560 DKDSSFDKTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMW 610
[50][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 150 bits (380), Expect = 4e-35
Identities = 78/175 (44%), Positives = 108/175 (61%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKI 360
R KG +++ + W P KSI+D+ + F G ++ PWS+ + PET I +L +
Sbjct: 365 RLKGTNEQNIKLWGAP-KSIKDLSDIFVRYLNGKVERLPWSD-SAVTPETSDIQNELLDL 422
Query: 359 NSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS 180
N GFLTINSQP+VN KS P GWG GYVYQKAYLE + +D L+ + + P
Sbjct: 423 NKRGFLTINSQPAVNGVKSTDPVHGWGPRNGYVYQKAYLELLVPPEHVDELLRRIEKNPD 482
Query: 179 ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
+TY VNK+ + + E NAVTWG+F +KE+IQPTIV+ SF WKDEA+++
Sbjct: 483 LTYYCVNKTGELKARSDEGP-NAVTWGIFASKEIIQPTIVESVSFMAWKDEAYQL 536
[51][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 150 bits (380), Expect = 4e-35
Identities = 75/169 (44%), Positives = 102/169 (60%)
Frame = -1
Query: 521 KKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFL 342
K++ W P KS ++ + F C + S PWS+L + E +I +QL +N N FL
Sbjct: 373 KEITTSWGSP-KSYSEIGDLFARYCEKKISSLPWSDLP-ISDEADLIRDQLLSMNRNAFL 430
Query: 341 TINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAV 162
TINSQP++N KS P GWG P GYV+QK Y+EFF L+ L E K S++Y
Sbjct: 431 TINSQPALNGEKSSHPVFGWGPPNGYVFQKPYVEFFVHPSLLNELKETVKKLNSVSYFVT 490
Query: 161 NKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
NK+ + +N+ NAVTWGVFP +E+IQPTIV+ SF WKDEA+ +
Sbjct: 491 NKNGDLDTNSQYEIPNAVTWGVFPNREIIQPTIVESTSFLAWKDEAYSL 539
[52][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 150 bits (379), Expect = 6e-35
Identities = 76/184 (41%), Positives = 109/184 (59%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSS-------PWSELDGLQPETKII 381
+ K ++L + W L S E V E F G + PW++ + L ET ++
Sbjct: 408 KSKSPKEELLKMWGEELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWND-EPLAAETSLM 466
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
E+L ++N G LTINSQP++N S P +GWG GGYV+QKAYLEFF S++ ++ L++
Sbjct: 467 KEELLRVNRQGVLTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQ 526
Query: 200 KSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
K + + Y V+ ++N E NAVTWG+FP +E+IQPT+VDP SF WKDEA
Sbjct: 527 VLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEA 586
Query: 23 FEIW 12
F +W
Sbjct: 587 FALW 590
[53][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 150 bits (379), Expect = 6e-35
Identities = 77/184 (41%), Positives = 108/184 (58%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSS-------PWSELDGLQPETKII 381
+ K ++L + W L S E V E F G + PW++ + L ET ++
Sbjct: 432 KSKSPKEELLKMWGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLL 490
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
E+L ++N G LTINSQP++N S P +GWG GGYV+QKAYLEFF S++ + L++
Sbjct: 491 KEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQ 550
Query: 200 KSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
K + + Y VN ++N E NAVTWG+FP +E+IQPT+VDP SF WKDEA
Sbjct: 551 VLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEA 610
Query: 23 FEIW 12
F +W
Sbjct: 611 FALW 614
[54][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 150 bits (379), Expect = 6e-35
Identities = 77/184 (41%), Positives = 108/184 (58%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSS-------PWSELDGLQPETKII 381
+ K ++L + W L S E V E F G + PW++ + L ET ++
Sbjct: 450 KSKSPKEELLKMWGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLL 508
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
E+L ++N G LTINSQP++N S P +GWG GGYV+QKAYLEFF S++ + L++
Sbjct: 509 KEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQ 568
Query: 200 KSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
K + + Y VN ++N E NAVTWG+FP +E+IQPT+VDP SF WKDEA
Sbjct: 569 VLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEA 628
Query: 23 FEIW 12
F +W
Sbjct: 629 FALW 632
[55][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 150 bits (379), Expect = 6e-35
Identities = 77/184 (41%), Positives = 108/184 (58%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSS-------PWSELDGLQPETKII 381
+ K ++L + W L S E V E F G + PW++ + L ET ++
Sbjct: 409 KSKSPKEELLKMWGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLL 467
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
E+L ++N G LTINSQP++N S P +GWG GGYV+QKAYLEFF S++ + L++
Sbjct: 468 KEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQ 527
Query: 200 KSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
K + + Y VN ++N E NAVTWG+FP +E+IQPT+VDP SF WKDEA
Sbjct: 528 VLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEA 587
Query: 23 FEIW 12
F +W
Sbjct: 588 FALW 591
[56][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 149 bits (377), Expect = 1e-34
Identities = 77/184 (41%), Positives = 107/184 (58%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSS-------PWSELDGLQPETKII 381
+ K ++L + W L S E V E F G + PW++ + L ET ++
Sbjct: 406 KSKSPREELLKMWGQELTSEESVFEVFAYYLSGEPNQNGYKVTCLPWND-EPLAAETSLL 464
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
E+L K+N G LTINSQP++N S P +GWG GGYV+QKAYLEFF S + + L++
Sbjct: 465 KEELQKVNRRGILTINSQPNINGKPSADPVVGWGPSGGYVFQKAYLEFFTSSETVAALLK 524
Query: 200 KSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
K + + Y VN ++N + NAVTWG+FP +E+IQPT+VDP SF WKDEA
Sbjct: 525 VLKKYELRVNYHIVNVKGENITNAPDMQPNAVTWGIFPGREIIQPTVVDPVSFMSWKDEA 584
Query: 23 FEIW 12
F +W
Sbjct: 585 FALW 588
[57][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 149 bits (377), Expect = 1e-34
Identities = 75/184 (40%), Positives = 110/184 (59%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGN-------LKSSPWSELDGLQPETKII 381
+ K ++L + W L S E V E F+ G + PW++ + L ET ++
Sbjct: 414 KSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLM 472
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
E+L ++N G LTINSQP++N S P +GWG GGYV+QKAYLEFF S++ ++ L++
Sbjct: 473 KEELLRVNRLGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQ 532
Query: 200 KSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
K + + Y V+ ++N E NAVTWG+FP +E++QPT+VDP SF WKDEA
Sbjct: 533 VLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIVQPTVVDPISFMFWKDEA 592
Query: 23 FEIW 12
F +W
Sbjct: 593 FALW 596
[58][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 149 bits (377), Expect = 1e-34
Identities = 75/184 (40%), Positives = 110/184 (59%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGN-------LKSSPWSELDGLQPETKII 381
+ K ++L + W L S E V E F+ G + PW++ + L ET ++
Sbjct: 449 KSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLM 507
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
E+L ++N G LTINSQP++N S P +GWG GGYV+QKAYLEFF S++ ++ L++
Sbjct: 508 KEELLRVNRLGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQ 567
Query: 200 KSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
K + + Y V+ ++N E NAVTWG+FP +E++QPT+VDP SF WKDEA
Sbjct: 568 VLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIVQPTVVDPISFMFWKDEA 627
Query: 23 FEIW 12
F +W
Sbjct: 628 FALW 631
[59][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 149 bits (377), Expect = 1e-34
Identities = 75/184 (40%), Positives = 109/184 (59%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSS-------PWSELDGLQPETKII 381
+ K ++L + W L S E V + F G + PW++ + L ET ++
Sbjct: 408 KSKSPKEELLKMWGEELTSEESVFQVFAHYLSGEPNQNGYKVTCLPWND-EPLAAETSLM 466
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
E+L ++N G LTINSQP++N S P +GWG GGYV+QKAYLEFF S++ ++ L++
Sbjct: 467 KEELLRVNRRGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQ 526
Query: 200 KSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
K + + Y V+ ++N E NAVTWG+FP +E+IQPT+VDP SF WKDEA
Sbjct: 527 VLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEA 586
Query: 23 FEIW 12
F +W
Sbjct: 587 FALW 590
[60][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 149 bits (377), Expect = 1e-34
Identities = 77/184 (41%), Positives = 110/184 (59%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGN-------LKSSPWSELDGLQPETKII 381
+ K ++L + W L S E V E F+ G + PW++ + L ET ++
Sbjct: 449 KSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLM 507
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
E+L ++N G LTINSQP++NA S P +GWG GGYV+QKAYLEFF S++ ++ L++
Sbjct: 508 KEELLRVNRLGILTINSQPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQ 567
Query: 200 KSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
K + + Y V+ ++N E NAVTWG+FP +E+IQPT+VDP SF WKDEA
Sbjct: 568 VLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEA 627
Query: 23 FEIW 12
F W
Sbjct: 628 FAPW 631
[61][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
RepID=UPI0000E814FF
Length = 508
Score = 149 bits (375), Expect = 2e-34
Identities = 79/185 (42%), Positives = 107/185 (57%), Gaps = 8/185 (4%)
Frame = -1
Query: 542 ARPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSS-------PWSELDGLQPETKI 384
++P R++ L+ W L E V E F G + PW++ D L ET +
Sbjct: 268 SKPSPREELLKM-WGEELTGEESVFEVFTCYITGEPNKNGHRVTCMPWND-DPLATETSL 325
Query: 383 INEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLV 204
+ EQL K+N G LTINSQP++N S P GWG GGYV+QKAYLEFF S + + L+
Sbjct: 326 LKEQLEKVNRRGILTINSQPNINGKPSTDPIFGWGPSGGYVFQKAYLEFFTSNEIVTALL 385
Query: 203 EKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDE 27
+ K + + Y VN ++N + NAVTWG+FP +E+IQPT+VDP SF WKDE
Sbjct: 386 KVLKKYELRVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDE 445
Query: 26 AFEIW 12
AF +W
Sbjct: 446 AFALW 450
[62][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 149 bits (375), Expect = 2e-34
Identities = 77/184 (41%), Positives = 107/184 (58%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSS-------PWSELDGLQPETKII 381
+ K + L + W L S E V E F G + PW++ + L ET ++
Sbjct: 432 KSKSPRELLLKMWGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLL 490
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
E+L ++N G LTINSQP++N S P +GWG GGYV+QKAYLEFF S++ + L++
Sbjct: 491 KEELLRVNRQGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQ 550
Query: 200 KSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
K + + Y VN ++N E NAVTWG+FP +E+IQPT+VDP SF WKDEA
Sbjct: 551 VLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEA 610
Query: 23 FEIW 12
F +W
Sbjct: 611 FALW 614
[63][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 149 bits (375), Expect = 2e-34
Identities = 77/184 (41%), Positives = 107/184 (58%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSS-------PWSELDGLQPETKII 381
+ K + L + W L S E V E F G + PW++ + L ET ++
Sbjct: 450 KSKSPRELLLKMWGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLL 508
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
E+L ++N G LTINSQP++N S P +GWG GGYV+QKAYLEFF S++ + L++
Sbjct: 509 KEELLRVNRQGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQ 568
Query: 200 KSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
K + + Y VN ++N E NAVTWG+FP +E+IQPT+VDP SF WKDEA
Sbjct: 569 VLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEA 628
Query: 23 FEIW 12
F +W
Sbjct: 629 FALW 632
[64][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Canis lupus familiaris RepID=UPI00005A03BF
Length = 780
Score = 149 bits (375), Expect = 2e-34
Identities = 76/184 (41%), Positives = 108/184 (58%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGN-------LKSSPWSELDGLQPETKII 381
+ K ++L + W L S E V E F G + PW++ + L ET ++
Sbjct: 534 KSKSPREELLKMWGEELTSEESVFEVFARYLSGEPNQHGYKVTCLPWND-EPLAAETSLM 592
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
E+L ++N G LTINSQP++N S P +GWG GGYV+QKAYLEFF S++ + L++
Sbjct: 593 KEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQ 652
Query: 200 KSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
K + + Y V+ ++N E NAVTWG+FP +E+IQPT+VDP SF WKDEA
Sbjct: 653 VLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEA 712
Query: 23 FEIW 12
F +W
Sbjct: 713 FALW 716
[65][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 149 bits (375), Expect = 2e-34
Identities = 76/184 (41%), Positives = 108/184 (58%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGN-------LKSSPWSELDGLQPETKII 381
+ K ++L + W L S E V E F G + PW++ + L ET ++
Sbjct: 450 KSKSPREELLKMWGEELTSEESVFEVFARYLSGEPNQHGYKVTCLPWND-EPLAAETSLM 508
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
E+L ++N G LTINSQP++N S P +GWG GGYV+QKAYLEFF S++ + L++
Sbjct: 509 KEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQ 568
Query: 200 KSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
K + + Y V+ ++N E NAVTWG+FP +E+IQPT+VDP SF WKDEA
Sbjct: 569 VLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEA 628
Query: 23 FEIW 12
F +W
Sbjct: 629 FALW 632
[66][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 149 bits (375), Expect = 2e-34
Identities = 75/180 (41%), Positives = 108/180 (60%), Gaps = 9/180 (5%)
Frame = -1
Query: 521 KKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFL 342
K+ Q+ W +P ++I D+ G L S PW + + +T II + L ++N N +
Sbjct: 375 KRAQELWGLP-QTISDITGLVISYLKGQLNSLPWFD-GAIGEDTNIILDHLIELNENSLI 432
Query: 341 TINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS------ 180
T+NSQPS+N+ +S GWG GYVYQK YLEFFC KD + L++ +
Sbjct: 433 TLNSQPSLNSVRSSDKVFGWGPKNGYVYQKQYLEFFCHKDVVARLLDHIDQYNKNQGDST 492
Query: 179 ---ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWS 9
I+Y AVNK+ N +SN + D+NAVTWGVFP +E++QPTIV+ SF WKDE + ++S
Sbjct: 493 SAVISYYAVNKNGNLISNCQDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYTLFS 552
[67][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 149 bits (375), Expect = 2e-34
Identities = 76/180 (42%), Positives = 111/180 (61%), Gaps = 9/180 (5%)
Frame = -1
Query: 521 KKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFL 342
KK + W +P +S+ D+ G+LKS PWS+ + +T++I + L +N +GF
Sbjct: 375 KKAFELWGLP-QSLADLSGIIINYLKGDLKSLPWSD-GPVGDDTRVIVDDLIYLNQHGFF 432
Query: 341 TINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF-------- 186
T+NSQP++NA KS GWG GYVYQK YLEFFC KD + L+++ + F
Sbjct: 433 TMNSQPALNAVKSSEKVFGWGPKNGYVYQKQYLEFFCHKDVVSKLLDQVEEFNIKGAESS 492
Query: 185 -PSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWS 9
I+Y AV+K N +N + D+NAVTWGVFP +E++QPTIV+ SF WKDE + +++
Sbjct: 493 SAFISYYAVDKDGNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFT 552
[68][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 149 bits (375), Expect = 2e-34
Identities = 79/180 (43%), Positives = 109/180 (60%), Gaps = 9/180 (5%)
Frame = -1
Query: 521 KKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFL 342
KK W P ++++D + G LKS PWS+ + +T ++ E L +N GFL
Sbjct: 375 KKAYDLWGTP-QTLKDFSDIIVSYLQGELKSLPWSD-GPIGEDTSVMVENLINLNHKGFL 432
Query: 341 TINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLV------EKSKAFPS 180
T+NSQP++NA KS GWG GYVYQK YLEFFC KD L L+ KS+ S
Sbjct: 433 TMNSQPALNAVKSSEKVYGWGPKNGYVYQKQYLEFFCPKDLLPKLLHTIDSYNKSEGDAS 492
Query: 179 ---ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWS 9
I+Y AV+K+ N +N + D+NAVTWGVFP +E++QPTIV+ SF WKDE + +++
Sbjct: 493 SSIISYYAVDKNGNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFT 552
[69][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 149 bits (375), Expect = 2e-34
Identities = 77/184 (41%), Positives = 107/184 (58%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSS-------PWSELDGLQPETKII 381
+ K + L + W L S E V E F G + PW++ + L ET ++
Sbjct: 409 KSKSPRELLLKMWGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLL 467
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
E+L ++N G LTINSQP++N S P +GWG GGYV+QKAYLEFF S++ + L++
Sbjct: 468 KEELLRVNRQGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQ 527
Query: 200 KSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
K + + Y VN ++N E NAVTWG+FP +E+IQPT+VDP SF WKDEA
Sbjct: 528 VLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEA 587
Query: 23 FEIW 12
F +W
Sbjct: 588 FALW 591
[70][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 149 bits (375), Expect = 2e-34
Identities = 75/184 (40%), Positives = 109/184 (59%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSS-------PWSELDGLQPETKII 381
+ K ++L + W L S E V + F G + PW++ + L ET ++
Sbjct: 408 KSKSPKEELLKMWGEELTSEESVFQVFAHHLSGEPNQNGYKVTCLPWND-EPLAAETSLM 466
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
E+L ++N G LTINSQP++N S P +GWG GGYV+QKAYLEFF S++ ++ L++
Sbjct: 467 KEELLRVNRRGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQ 526
Query: 200 KSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
K + + Y V+ ++N E NAVTWG+FP +E+IQPT+VDP SF WKDEA
Sbjct: 527 VLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEA 586
Query: 23 FEIW 12
F +W
Sbjct: 587 FALW 590
[71][TOP]
>UniRef100_A8XGR9 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis briggsae
RepID=A8XGR9_CAEBR
Length = 724
Score = 148 bits (374), Expect = 2e-34
Identities = 78/181 (43%), Positives = 111/181 (61%), Gaps = 21/181 (11%)
Frame = -1
Query: 491 LKSIEDVQEKFKELCIGNLKSS-------PWSELD-GLQPETKIINEQLGKINSNGFLTI 336
++SIEDV+ F S PW+E + G+QPET +I+EQL N NG LT+
Sbjct: 490 IESIEDVKRVFINYITQTPNVSGKKVTVLPWTEAETGVQPETSLISEQLVWCNENGILTV 549
Query: 335 NSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE-KSKAFP-SITYMAV 162
NSQPSVN A S P +GWG PGGY YQKAYLE F + + + L++ + +P + Y A+
Sbjct: 550 NSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSEKLIDIIEREYPVRVNYHAI 609
Query: 161 NKSENWV-----------SNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
+K +++ +N+ E+ AVTWGVFP E+ QPT+VDP SF+ W+DEA+++
Sbjct: 610 DKDVSYILNSHDSMQIFRTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQM 669
Query: 14 W 12
W
Sbjct: 670 W 670
[72][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 148 bits (374), Expect = 2e-34
Identities = 79/182 (43%), Positives = 111/182 (60%), Gaps = 11/182 (6%)
Frame = -1
Query: 521 KKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFL 342
KK + W +P +S+ ++ G+LKS PWS+ + +TK+I + L +N +GF
Sbjct: 375 KKAFELWGLP-QSLAELSGIIINYLKGDLKSLPWSD-GPVGDDTKVIVDDLIYLNQHGFF 432
Query: 341 TINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLV-----------EKS 195
T+NSQP++NA KS GWG GYVYQK YLEFFC KD + L+ E S
Sbjct: 433 TMNSQPALNAVKSSEKVFGWGPKNGYVYQKQYLEFFCHKDVVSKLLDHVEEFNVKGAESS 492
Query: 194 KAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
AF I+Y AV+K N +N + D+NAVTWGVFP +E++QPTIV+ SF WKDE + +
Sbjct: 493 SAF--ISYYAVDKDGNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRL 550
Query: 14 WS 9
++
Sbjct: 551 FT 552
[73][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 148 bits (373), Expect = 3e-34
Identities = 77/184 (41%), Positives = 106/184 (57%), Gaps = 8/184 (4%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSS-------PWSELDGLQPETKII 381
+ K ++L + W L E V E F G + PW++ D L ET ++
Sbjct: 411 KSKSPREELLKMWGEELTGEESVFEVFTCYITGEPNKNGYKVTCMPWND-DPLATETNLL 469
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
+QL K+N G LTINSQP++N S P +GWG GGYV+QKAYLEFF S + + L++
Sbjct: 470 KDQLEKVNRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLK 529
Query: 200 KSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 24
K + + Y VN ++N + NAVTWG+FP +E+IQPT+VDP SF WKDEA
Sbjct: 530 VLKKYELRVNYHIVNVQGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEA 589
Query: 23 FEIW 12
F +W
Sbjct: 590 FALW 593
[74][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 148 bits (373), Expect = 3e-34
Identities = 76/172 (44%), Positives = 100/172 (58%)
Frame = -1
Query: 530 GRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSN 351
G ++ +++W P K+I+D+ E F ++S PWSE L E I + L ++N
Sbjct: 367 GSNEANRKKWGEP-KAIQDIAELFVSYLNNKIESLPWSE-SPLTTEADEIRDDLIELNKR 424
Query: 350 GFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITY 171
G LTINSQP+VN KS P GWG GYVYQK+YLE D ++ + + P +TY
Sbjct: 425 GLLTINSQPAVNGVKSSHPIHGWGPDNGYVYQKSYLELLVHPGVFDKMISRIENHPDLTY 484
Query: 170 MAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
AV K SN NAVTWGVFP KE++QPTIV+ SF WKDEAF +
Sbjct: 485 YAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRL 536
[75][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 148 bits (373), Expect = 3e-34
Identities = 79/173 (45%), Positives = 105/173 (60%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ + W P KSI+D+ F G L PWSE + ET I + L +N+
Sbjct: 366 KGTNEQNIKLWGEP-KSIKDLSAIFIRFLEGGLDRLPWSE-SPITEETDDIKQDLIDLNN 423
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
GFLTINSQP+VN S P GWG GYVYQKAYLE + + ++ + + P +T
Sbjct: 424 RGFLTINSQPAVNGMSSSHPVYGWGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNPDLT 483
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y A+NK+ +NT +S NAVTWG+F +KEVIQPTIV+ SF WKDEAF +
Sbjct: 484 YYAINKNGELKTNTSDSP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAFRL 535
[76][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 148 bits (373), Expect = 3e-34
Identities = 78/173 (45%), Positives = 105/173 (60%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ + W P KSI+D+ F L PWSE + ET II + L +N+
Sbjct: 366 KGTNEQNIKLWGEP-KSIKDLSSIFVRFLEAKLDRLPWSE-SSITEETDIIKQDLIDLNN 423
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
GFLTINSQP++N A S P GWG GYVYQKAYLE + +D ++ + + +T
Sbjct: 424 RGFLTINSQPAINGASSSHPVYGWGPKNGYVYQKAYLELLIPPEIIDEVITRIQKNADLT 483
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y A NK+ +NT +S NAVTWG+F +KEVIQPTIV+ SF WKDEA+ +
Sbjct: 484 YYATNKNGELKTNTSDSP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRL 535
[77][TOP]
>UniRef100_UPI0000ECA34F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Gallus
gallus RepID=UPI0000ECA34F
Length = 640
Score = 147 bits (371), Expect = 5e-34
Identities = 77/178 (43%), Positives = 103/178 (57%), Gaps = 8/178 (4%)
Frame = -1
Query: 521 KKLQQEWVVPLKSIEDVQEKFKELCIGNLKSS-------PWSELDGLQPETKIINEQLGK 363
++L + W L E V E F G + PW++ D L ET ++ EQL K
Sbjct: 406 EELLKMWGEELTGEESVFEVFTCYITGEPNKNGHRVTCMPWND-DPLATETSLLKEQLEK 464
Query: 362 INSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP 183
+N G LTINSQP++N S P GWG GGYV+QKAYLEFF S + + L++ K +
Sbjct: 465 VNRRGILTINSQPNINGKPSTDPIFGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYE 524
Query: 182 -SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
+ Y VN ++N + NAVTWG+FP +E+IQPT+VDP SF WKDEAF +W
Sbjct: 525 LRVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALW 582
[78][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 147 bits (371), Expect = 5e-34
Identities = 76/178 (42%), Positives = 106/178 (59%), Gaps = 3/178 (1%)
Frame = -1
Query: 530 GRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSN 351
G ++ +++W P ++++D+ F L+ PWSE + E ++I + L +N+
Sbjct: 367 GSNELNRKKWGEP-QTVKDIANLFVRYLNQELEYLPWSEAP-ISSEAELIKDDLIALNNR 424
Query: 350 GFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITY 171
G +TINSQP+VN KS P GWG GYVYQKAYLE S + + + + P ITY
Sbjct: 425 GLITINSQPAVNGVKSTHPVHGWGPANGYVYQKAYLELLVSPELFPEIKRRIEDHPDITY 484
Query: 170 MAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI---WSR 6
AV KS N +N NAVTWGVFP KE++QPTIV+ SF WKDEAF++ W+R
Sbjct: 485 YAVTKSGNLHTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQLGLEWAR 542
[79][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 147 bits (371), Expect = 5e-34
Identities = 79/173 (45%), Positives = 104/173 (60%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ + W P KSI+D+ F G L PWSE + ET I L +N+
Sbjct: 366 KGTNEQNIKLWGEP-KSIKDLSAIFIRFLEGGLDRLPWSE-SPITEETDDIKHDLIDLNN 423
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
GFLTINSQP+VN S P GWG GYVYQKAYLE + + ++ + + P +T
Sbjct: 424 RGFLTINSQPAVNGMSSSHPVYGWGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNPDLT 483
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y A+NK+ +NT +S NAVTWG+F +KEVIQPTIV+ SF WKDEAF +
Sbjct: 484 YYAINKNGELKTNTSDSP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAFRL 535
[80][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 146 bits (369), Expect = 8e-34
Identities = 79/179 (44%), Positives = 106/179 (59%), Gaps = 3/179 (1%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ + W P KSI+D+ + F G L PWS+ + E I E L K+N
Sbjct: 366 KGTNEQNIKLWGEP-KSIKDISDIFVNFLTGKLDRLPWSD-SPITTEAHEIQEDLLKLNQ 423
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
GFLTINSQP+VN KS P GWG G+VYQKAYLE + +D L+ + + +T
Sbjct: 424 RGFLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSNLIDELITRIEKNDDLT 483
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAF---EIWSR 6
Y A NK +NT +S NA+TWG+F +E+IQPTIV+ SF WKDEA+ E WS+
Sbjct: 484 YHATNKKGELKTNTRDSP-NALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGEHWSK 541
[81][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 145 bits (367), Expect = 1e-33
Identities = 76/173 (43%), Positives = 104/173 (60%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ + W P S+ D+ E F GNL PWS+ + PET I + L ++N
Sbjct: 366 KGTNEQNIKLWGEP-NSLRDLAEVFVRFLEGNLDRLPWSD-SPITPETSAIKDALVELNR 423
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
GF TINSQP+VN KS P GWG G+VYQKAYLE +D L+ + +A +T
Sbjct: 424 RGFFTINSQPAVNGVKSSHPVFGWGPKNGFVYQKAYLELLVPPYVIDELIARIEANEDLT 483
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y AV K +NT +S NA+TWG+F +EV+QPTIV+ SF WKDEA+++
Sbjct: 484 YHAVTKKGELRTNTRDSP-NALTWGIFAGREVVQPTIVETVSFLAWKDEAYQL 535
[82][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 145 bits (367), Expect = 1e-33
Identities = 76/173 (43%), Positives = 105/173 (60%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ + W P KS++++ E F GNL PWSE + ET ++ L +N
Sbjct: 366 KGTNEQNIKLWGEP-KSLKELSEIFVRFLNGNLDRLPWSE-GAVTEETDVLKLDLLDLNR 423
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
GFLTINSQP+++ S P GWG GYVYQKAYLE S +D ++ + + P +T
Sbjct: 424 RGFLTINSQPAIDGMPSSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLT 483
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y VNK +NT +S NAVTWG+F +KE+IQPTIV+ SF WKDEA+ +
Sbjct: 484 YYCVNKKGELRTNTTDSP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL 535
[83][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 145 bits (367), Expect = 1e-33
Identities = 77/173 (44%), Positives = 105/173 (60%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ + W P KS++++ E F GNL PWSE + ET +I L +N
Sbjct: 352 KGTNEQNIKLWGEP-KSLKELSEIFVRFLNGNLDRLPWSE-GAVTEETDVIKLDLLDLNR 409
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
GFLTINSQP+++ S P GWG GYVYQKAYLE S +D ++ + + P +T
Sbjct: 410 RGFLTINSQPAIDGMPSSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLT 469
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y VNK +NT +S NAVTWG+F +KE+IQPTIV+ SF WKDEA+ +
Sbjct: 470 YYCVNKIGELRTNTTDSP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL 521
[84][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 145 bits (367), Expect = 1e-33
Identities = 75/182 (41%), Positives = 110/182 (60%), Gaps = 11/182 (6%)
Frame = -1
Query: 521 KKLQQEWVVP--LKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNG 348
K+ + W P LK + D+ + + G+LKS PWS+ + +TK+I + L ++N G
Sbjct: 376 KRAYELWGTPGSLKELSDIVISYLK---GDLKSLPWSD-GSVGDDTKVIVDDLVELNKRG 431
Query: 347 FLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS---- 180
LT+NSQP++N+ KS GWG GYVYQK YLEFFC KD + L++ + +
Sbjct: 432 LLTMNSQPALNSIKSSEKIFGWGPKNGYVYQKQYLEFFCHKDIIVKLLQTIDDYNNNQGD 491
Query: 179 -----ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
I+Y AV+ N +N + D+NAVTWGVFP +E++QPTIV+ SF WKDE + +
Sbjct: 492 ASSAIISYYAVDLKGNLTTNCNDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRL 551
Query: 14 WS 9
+S
Sbjct: 552 FS 553
[85][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 145 bits (366), Expect = 2e-33
Identities = 75/178 (42%), Positives = 107/178 (60%), Gaps = 3/178 (1%)
Frame = -1
Query: 530 GRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSN 351
G +++ +++W P SI+D+ F ++ PWSE + E +I + L ++N+
Sbjct: 367 GSNEQNRKKWGEPT-SIKDIANLFVRYLNKEIEYLPWSEAP-VAEEADLIKDDLIELNNR 424
Query: 350 GFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITY 171
G +T+NSQP+VN KS P GWG GYVYQKAYLE S + + + ++ P +TY
Sbjct: 425 GLITVNSQPAVNGVKSTHPIHGWGPANGYVYQKAYLEMLISPELFPQIKSRIESHPDLTY 484
Query: 170 MAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI---WSR 6
AV KS N +N NAVTWGVFP KE++QPTIV+ SF WKDEAF++ W+R
Sbjct: 485 HAVTKSGNLHTNAQFEGPNAVTWGVFPGKEIVQPTIVERISFLAWKDEAFQLGMEWAR 542
[86][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 145 bits (366), Expect = 2e-33
Identities = 77/173 (44%), Positives = 105/173 (60%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ Q W P KS++++ E F G L PWSE + ET II L +NS
Sbjct: 366 KGTNEQNIQLWGKP-KSLKELSEIFIHFLNGKLDRLPWSE-GAVTEETDIIKRDLLDLNS 423
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
GFLTINSQP+++ S P GWG GYVYQKAYLE S ++ ++ + + +T
Sbjct: 424 RGFLTINSQPAIDGVHSSHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLT 483
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y VNK+ +NT +S NAVTWG+F +KE+IQPTIV+ SF WKDEA+ +
Sbjct: 484 YYCVNKTGELRTNTSDSP-NAVTWGIFVSKEIIQPTIVETISFLAWKDEAYRL 535
[87][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 145 bits (366), Expect = 2e-33
Identities = 77/173 (44%), Positives = 105/173 (60%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ Q W P KS++++ E F G L PWSE + ET II L +NS
Sbjct: 366 KGTNEQNIQLWGKP-KSLKELSEIFIRFLNGKLDRLPWSE-GAVTEETDIIKRDLLDLNS 423
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
GFLTINSQP+++ S P GWG GYVYQKAYLE S ++ ++ + + +T
Sbjct: 424 RGFLTINSQPAIDGVHSSHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLT 483
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y VNK+ +NT +S NAVTWG+F +KE+IQPTIV+ SF WKDEA+ +
Sbjct: 484 YYCVNKTGELRTNTSDSP-NAVTWGIFVSKEIIQPTIVETISFLAWKDEAYRL 535
[88][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6H337_AJECH
Length = 524
Score = 145 bits (365), Expect = 2e-33
Identities = 76/173 (43%), Positives = 105/173 (60%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ + W P KS++++ E F GNL PWSE + ET ++ L +N
Sbjct: 257 KGTNEQNIKLWGEP-KSLKELSEIFVRFLNGNLDRLPWSE-GAVTEETDVLKLDLLDLNR 314
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
GFLTINSQP+++ S P GWG GYVYQKAYLE S +D ++ + + P +T
Sbjct: 315 RGFLTINSQPAIDGMPSSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLT 374
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y VNK +NT +S NAVTWG+F +KE+IQPTIV+ SF WKDEA+ +
Sbjct: 375 YYCVNKIGELRTNTTDSP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL 426
[89][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 144 bits (364), Expect = 3e-33
Identities = 75/173 (43%), Positives = 104/173 (60%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ + W P KSI D+ + F G L PWS+ + E I + L ++NS
Sbjct: 366 KGTNEQNIKLWGEP-KSIRDITQIFVRYLEGKLDRLPWSD-SPISGEANAIKDNLVQLNS 423
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
G LT+NSQP+VN +S P GWG G+VYQKAYLE F LD L+ + + P +T
Sbjct: 424 RGLLTVNSQPAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLT 483
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y AV K+ +NT +S NA+TWG+F +E++QPTIVD SF WKDEA+ +
Sbjct: 484 YHAVAKNRELRTNTRDSP-NALTWGIFAGREIVQPTIVDTISFLAWKDEAYRL 535
[90][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 144 bits (364), Expect = 3e-33
Identities = 77/173 (44%), Positives = 105/173 (60%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ Q W P KS++++ E F G L PWSE + ET II L +NS
Sbjct: 366 KGTNEQNIQLWGKP-KSLKELSEIFIRFLNGKLDRLPWSE-GAVTEETDIIKRDLLDLNS 423
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
GFLTINSQP+++ S P GWG GYVYQKAYLE S ++ ++ + + +T
Sbjct: 424 RGFLTINSQPAIDGVHSSHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLT 483
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y VNK+ +NT +S NAVTWG+F +KE+IQPTIV+ SF WKDEA+ +
Sbjct: 484 YYCVNKTGELRTNTTDSP-NAVTWGIFVSKEIIQPTIVETISFLAWKDEAYRL 535
[91][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 144 bits (364), Expect = 3e-33
Identities = 75/173 (43%), Positives = 104/173 (60%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ + W P KSI D+ + F G L PWS+ + E I + L ++NS
Sbjct: 366 KGTNEQNIKLWGEP-KSIRDITQIFVRYLEGKLDRLPWSD-SPISGEANAIKDNLVQLNS 423
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
G LT+NSQP+VN +S P GWG G+VYQKAYLE F LD L+ + + P +T
Sbjct: 424 RGLLTVNSQPAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLT 483
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y AV K+ +NT +S NA+TWG+F +E++QPTIVD SF WKDEA+ +
Sbjct: 484 YHAVAKNRELRTNTRDSP-NALTWGIFAGREIVQPTIVDTISFLAWKDEAYRL 535
[92][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 144 bits (363), Expect = 4e-33
Identities = 74/161 (45%), Positives = 101/161 (62%), Gaps = 4/161 (2%)
Frame = -1
Query: 479 EDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSD 300
+ V+ F + G +K PW + ET I +QL ++N LTINSQP VN A S
Sbjct: 367 DHVRRVFTDFIKGEVKRLPWCTEPPTE-ETLFIQKQLIRLNQCNMLTINSQPRVNGALST 425
Query: 299 SPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE--KSKAFPSITYMAVNKSENWVSNT-- 132
P +GWG GG+VYQKAY+EFFC + +L+ L+ +++ + SI+YMAV + V +
Sbjct: 426 DPYVGWGPAGGFVYQKAYVEFFCPEGQLEQLIRGIEAEKYDSISYMAVTADGSKVRSNIP 485
Query: 131 GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWS 9
+ VNAVTWGVFP E+IQPT+VD SF WKDEAF +W+
Sbjct: 486 PQGQVNAVTWGVFPNSEIIQPTVVDVTSFMAWKDEAFALWN 526
[93][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 144 bits (363), Expect = 4e-33
Identities = 77/171 (45%), Positives = 107/171 (62%)
Frame = -1
Query: 521 KKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFL 342
+K+ + W P K+++D++ G L S PWS++ + E + I Q+ ++N+ G L
Sbjct: 370 QKVLELWGEP-KTVDDLKTLLVNYLNGKLASLPWSDVP-ISNEIETIKPQILELNNRGIL 427
Query: 341 TINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAV 162
TINSQP+VN AKS P GWG GYVYQKAYLE + + + LV+K + IT+ AV
Sbjct: 428 TINSQPAVNGAKSTHPVHGWGPKNGYVYQKAYLELLVTPEVAEKLVKKLENQSEITFYAV 487
Query: 161 NKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWS 9
NK+ N +N NAVTWG++P KEVIQPTIV+ SF WK+EAF + S
Sbjct: 488 NKTGNLQTN-APGGPNAVTWGIYPGKEVIQPTIVEKISFLAWKEEAFRLGS 537
[94][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 144 bits (363), Expect = 4e-33
Identities = 75/175 (42%), Positives = 107/175 (61%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKI 360
R KG +++ + W P KSI+D+ + F G L+ PWS+ + ET I +L +
Sbjct: 365 RLKGTNEQNIKLWGAP-KSIKDLSDIFLRYLNGKLERLPWSD-SSVTLETSDIQNELLDL 422
Query: 359 NSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS 180
N GFLTINSQP+VN KS P GWG G+VYQKAYLE + ++ L+ + + P
Sbjct: 423 NKRGFLTINSQPAVNGVKSTDPVHGWGPRNGFVYQKAYLELLVPPEHVEELLRRIEKNPD 482
Query: 179 ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
+TY +NK+ + + E NAVTWG+F +KE+IQPTIV+ SF WKDEA+++
Sbjct: 483 LTYYCINKTGELRARSDEGP-NAVTWGIFASKEIIQPTIVESVSFMAWKDEAYQL 536
[95][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 144 bits (362), Expect = 5e-33
Identities = 75/162 (46%), Positives = 103/162 (63%), Gaps = 5/162 (3%)
Frame = -1
Query: 479 EDVQEK-FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKS 303
++ Q+K F + G +K PW + ET I +QL ++N LTINSQP VN A S
Sbjct: 345 KETQDKVFTDFIKGEVKRLPWCTEPPTE-ETLFIQKQLIRLNQCNMLTINSQPRVNGALS 403
Query: 302 DSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE--KSKAFPSITYMAVNKSENWVSNT- 132
P +GWG GG+VYQKAY+EFFC + +L+ L+ +++ + SI+YMAV + V +
Sbjct: 404 TDPYVGWGPAGGFVYQKAYVEFFCPEGQLEQLIRGIEAEKYDSISYMAVTADGSKVRSNI 463
Query: 131 -GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWS 9
+ VNAVTWGVFP E+IQPT+VD SF WKDEAF +W+
Sbjct: 464 PPQGQVNAVTWGVFPNSEIIQPTVVDVTSFMAWKDEAFALWN 505
[96][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S5W8_NEMVE
Length = 619
Score = 144 bits (362), Expect = 5e-33
Identities = 81/182 (44%), Positives = 105/182 (57%), Gaps = 8/182 (4%)
Frame = -1
Query: 527 RDKKLQQEWVVPLKSIEDVQEKFKELCIGN-------LKSSPWSELDGLQPETKIINEQL 369
+D +L W L S +DV + F G + PWS+ + L PET + E+L
Sbjct: 387 KDSELLSMWGRELNSEQDVFDIFVCYLTGRDNKQGFKVTELPWSDGE-LAPETIPLVEKL 445
Query: 368 GKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKA 189
N NG LTINSQPS+NA S+ P GWG PGGYV+QKAYLEFF ++ L + K
Sbjct: 446 VHANQNGILTINSQPSLNAVPSEDPNHGWGKPGGYVFQKAYLEFFAREEIALELYHQLKD 505
Query: 188 FPSITYMAVNKS-ENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
I + VN S E+ +N NAVTWGVFP E++QPT+VDP +F WKDEAF +W
Sbjct: 506 GTRINFHLVNSSGESDFTNANMYSPNAVTWGVFPGSEILQPTVVDPIAFHYWKDEAFGLW 565
Query: 11 SR 6
+
Sbjct: 566 KQ 567
[97][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 144 bits (362), Expect = 5e-33
Identities = 76/173 (43%), Positives = 105/173 (60%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ + W P KS++++ E F G+L PWSE + ET+II L +N
Sbjct: 366 KGTNEQNIKLWGEP-KSLKELSEIFIRFLNGSLDRLPWSE-GAVTEETEIIKSDLLDLNR 423
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
GFLTINSQP+++ S P GWG GYVYQKAYLE S +D ++ + + +T
Sbjct: 424 KGFLTINSQPAIDGMPSSHPIYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNSDLT 483
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y VNK +NT +S NAVTWG+F +KE+IQPTIV+ SF WKDEA+ +
Sbjct: 484 YYCVNKKGELKTNTTDSP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL 535
[98][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 144 bits (362), Expect = 5e-33
Identities = 76/173 (43%), Positives = 105/173 (60%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ + W P KS++++ E F G+L PWSE + ET+II L +N
Sbjct: 366 KGTNEQNIKLWGEP-KSLKELSEIFIRFLNGSLDRLPWSE-GAVTEETEIIKSDLLDLNR 423
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
GFLTINSQP+++ S P GWG GYVYQKAYLE S +D ++ + + +T
Sbjct: 424 KGFLTINSQPAIDGMPSSHPIYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNSDLT 483
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y VNK +NT +S NAVTWG+F +KE+IQPTIV+ SF WKDEA+ +
Sbjct: 484 YYCVNKKGELKTNTTDSP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL 535
[99][TOP]
>UniRef100_UPI000151BABB hypothetical protein PGUG_04648 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151BABB
Length = 355
Score = 143 bits (361), Expect = 7e-33
Identities = 74/171 (43%), Positives = 102/171 (59%), Gaps = 8/171 (4%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQP 324
W P +S +D+ +LKS PWS+ + +T II ++L +N GFLT+NSQP
Sbjct: 121 WGCP-QSFKDLSNLVVSYLKNDLKSLPWSD-GPIGEDTAIIVDKLISLNQRGFLTMNSQP 178
Query: 323 SVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS--------ITYM 168
S+N KS+ GWG GYV+QK YLEFFC +D L+E + F +TY
Sbjct: 179 SLNCVKSNDKVYGWGPKNGYVFQKQYLEFFCHRDIFPKLLESIEKFNEKGGESCSFLTYY 238
Query: 167 AVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
A +K+ +NT E D+NAVTWGVFP +E++QPTIV+ SF WKDE + +
Sbjct: 239 AADKNGELNTNTKEDDINAVTWGVFPGEEILQPTIVEKTSFFAWKDEVYRL 289
[100][TOP]
>UniRef100_A5DMZ7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DMZ7_PICGU
Length = 355
Score = 143 bits (361), Expect = 7e-33
Identities = 74/171 (43%), Positives = 102/171 (59%), Gaps = 8/171 (4%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQP 324
W P +S +D+ +LKS PWS+ + +T II ++L +N GFLT+NSQP
Sbjct: 121 WGCP-QSFKDLSNLVVSYLKNDLKSLPWSD-GPIGEDTAIIVDKLISLNQRGFLTMNSQP 178
Query: 323 SVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS--------ITYM 168
S+N KS+ GWG GYV+QK YLEFFC +D L+E + F +TY
Sbjct: 179 SLNCVKSNDKVYGWGPKNGYVFQKQYLEFFCHRDIFPKLLESIEKFNEKGGESCSFLTYY 238
Query: 167 AVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
A +K+ +NT E D+NAVTWGVFP +E++QPTIV+ SF WKDE + +
Sbjct: 239 AADKNGELNTNTKEDDINAVTWGVFPGEEILQPTIVEKTSFFAWKDEVYRL 289
[101][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 143 bits (361), Expect = 7e-33
Identities = 75/173 (43%), Positives = 104/173 (60%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ + W P KSI DV + F G L PWS+ + E I + L ++NS
Sbjct: 366 KGTNEQNIKLWGEP-KSIRDVTQIFVRYLEGKLDRLPWSD-SPISGEANAIKDNLVQLNS 423
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
G LT+NSQP+VN +S P GWG G+VYQKAYLE F LD L+ + + P +T
Sbjct: 424 RGLLTVNSQPAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLT 483
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y AV K+ +NT +S NA+TWG+F +E++QPTIV+ SF WKDEA+ +
Sbjct: 484 YHAVAKNRELRTNTRDSP-NALTWGIFAGREIVQPTIVETISFLAWKDEAYRL 535
[102][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 142 bits (359), Expect = 1e-32
Identities = 77/178 (43%), Positives = 103/178 (57%), Gaps = 8/178 (4%)
Frame = -1
Query: 521 KKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFL 342
K+ + W P +SI+DV + F GNL S PWS+ + E ++ + L +N G L
Sbjct: 368 KRAVELWGKP-QSIDDVIDLFVRYLQGNLSSLPWSDGE-TSKEINVLLDDLLALNRQGIL 425
Query: 341 TINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEK--------SKAF 186
TINSQP VN S+ GWG G+VYQK YLEFF L L+ S F
Sbjct: 426 TINSQPCVNGLPSNHNVHGWGPSNGFVYQKQYLEFFIPAKFLTKLISNIEELNKSYSSNF 485
Query: 185 PSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
++T+ AVN ++N+ E D+NAVTWG+FP KEV+QPTIV+ SF WKDEAF ++
Sbjct: 486 NTLTFYAVNAQGELITNSKEDDINAVTWGIFPGKEVVQPTIVERCSFLAWKDEAFRVF 543
[103][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 142 bits (359), Expect = 1e-32
Identities = 77/173 (44%), Positives = 104/173 (60%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ Q W P KSI+D+ F G L PWS+ + E K I L ++N+
Sbjct: 366 KGTNEQNIQLWGEP-KSIKDLSRLFVRYLEGKLSRLPWSDTP-ISSEAKAIKPNLIELNN 423
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
G LTINSQP+VN AKS P GWG G+VYQKAYLE LD L+ + + +T
Sbjct: 424 RGILTINSQPAVNGAKSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIEGNEDLT 483
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y AV+K+ +NT +S NA+TWG+F +EV+QPTIV+ SF WKDEA+ +
Sbjct: 484 YHAVSKNGELRTNTHDSP-NALTWGIFAGREVVQPTIVETISFLAWKDEAYRL 535
[104][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 142 bits (359), Expect = 1e-32
Identities = 74/164 (45%), Positives = 96/164 (58%), Gaps = 3/164 (1%)
Frame = -1
Query: 488 KSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAA 309
KS++D+ F + + PWSE L E + I + L +N G +TINSQP+VN
Sbjct: 375 KSVKDIATLFVRYVQKEVDTLPWSE-SPLDAEAEQIRDDLIDLNLRGLITINSQPAVNGV 433
Query: 308 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 129
+S P GWG P GYVYQKAYLE + L E+ P +TY AV KS N +N
Sbjct: 434 RSTHPIHGWGPPNGYVYQKAYLELLVHPAIFEQLKERIHDHPDLTYYAVTKSGNLHTNAT 493
Query: 128 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI---WSR 6
NAVTWGVFP KE++QPT+V+ SF WKDEAF++ W+R
Sbjct: 494 YEGPNAVTWGVFPGKEIVQPTVVENISFLAWKDEAFQLGMEWAR 537
[105][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 142 bits (358), Expect = 2e-32
Identities = 79/181 (43%), Positives = 110/181 (60%), Gaps = 4/181 (2%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
K D +++ W P ++I D+ F C L PWS++ L E+ II ++L ++N
Sbjct: 374 KQTDAEIRALWGSP-ENIRDLGNVFAAYCERKLACLPWSDIP-LSGESAIIADKLAELNR 431
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
G LTINSQP V AA S P GWG GYV+QKAYLEFF D++ +L+E +F ++
Sbjct: 432 QGILTINSQPPVCAAPSTDPLFGWGPAHGYVFQKAYLEFFMHPDQVKSLLEVIPSFKTVQ 491
Query: 173 YMAVNKSENWVSNTGESDV-NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI---WSR 6
Y + E + GE DV +AVTWGVFP EVIQPT+V+ ASF WKDEA+ + W++
Sbjct: 492 YY-ITDYEGSLETNGELDVPSAVTWGVFPNSEVIQPTVVESASFLAWKDEAYSLGLSWAK 550
Query: 5 S 3
+
Sbjct: 551 A 551
[106][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 140 bits (354), Expect = 4e-32
Identities = 71/172 (41%), Positives = 99/172 (57%)
Frame = -1
Query: 530 GRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSN 351
G ++ +++W P K+++D+ + F + S PWSE L E I + L ++N
Sbjct: 367 GTNEANRKKWGEP-KTVQDIAQLFVRYLRNEIDSLPWSE-SPLTSEADEIRDDLVELNKR 424
Query: 350 GFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITY 171
G LT+NSQP+VN KS GWG GYVYQK+YLE D + ++ + + P +T+
Sbjct: 425 GLLTVNSQPAVNGVKSSHAVHGWGPSNGYVYQKSYLELLVHPDVFNDMIGRIENHPDLTF 484
Query: 170 MAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
AV K SN NAVTWGVFP KE++QPTIV+ SF WKDEAF +
Sbjct: 485 YAVTKDGELRSNAPSDCPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRL 536
[107][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 139 bits (351), Expect = 1e-31
Identities = 74/178 (41%), Positives = 102/178 (57%), Gaps = 3/178 (1%)
Frame = -1
Query: 530 GRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSN 351
G +++ +Q+W P I D+ F ++ PWSE + E +I + L +N
Sbjct: 367 GTNEQNRQKWGEPT-CIRDIANLFVRYLKKEIEYLPWSEAP-VAEEADLIKDYLLDLNKR 424
Query: 350 GFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITY 171
G +T+NSQP+VN KS P GWG GYVYQKAYLE S + + ++ + P +TY
Sbjct: 425 GLITVNSQPAVNGVKSTHPVHGWGPSKGYVYQKAYLELLVSPEVYPEIKKRIENHPDLTY 484
Query: 170 MAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI---WSR 6
AV KS +N NAVTWGVFP KE++QPTIV+ SF WKDEAF++ W+R
Sbjct: 485 HAVTKSGMLETNAPSDAPNAVTWGVFPGKEIVQPTIVERISFLAWKDEAFQLGSDWAR 542
[108][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 139 bits (350), Expect = 1e-31
Identities = 73/173 (42%), Positives = 102/173 (58%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ + W P KSI D+ + F G L+ PWS+ + E I E L ++N
Sbjct: 366 KGTNEQNIKLWGEP-KSIRDISQIFVRYVEGKLERLPWSD-SPISAEANAIKENLIELNG 423
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
G LT+NSQP+VN +S P GWG G+VYQKAYLE F LD L+ + + +T
Sbjct: 424 RGLLTVNSQPAVNGVRSSHPVYGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNDDLT 483
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y AV K +NT +S NA+TWG+F +E++QPTIV+ SF WKDEA+ +
Sbjct: 484 YHAVAKEGELRTNTRDSP-NALTWGIFAGREIVQPTIVETISFLAWKDEAYRL 535
[109][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 139 bits (349), Expect = 2e-31
Identities = 76/180 (42%), Positives = 102/180 (56%), Gaps = 11/180 (6%)
Frame = -1
Query: 521 KKLQQEWVVP--LKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNG 348
KK W P LK D+ F G L S PWS+ + +++II + L +N G
Sbjct: 375 KKAFDLWGHPGTLKQFSDIIISFLS---GKLNSLPWSD-SAIGQDSEIIVDNLIALNKKG 430
Query: 347 FLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF------ 186
F T+NSQPS+NA KS+ GWG GYVYQK YLEFF KD + L+ + +
Sbjct: 431 FFTLNSQPSLNAIKSNDKVYGWGPKNGYVYQKQYLEFFVHKDIIPALLHQIDNYNRGQGD 490
Query: 185 ---PSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
+TY AV++ SNT + D+NAVTWGVFP +E++QPTIV+ SF WKDE + +
Sbjct: 491 SNSSVLTYYAVDQKGKLFSNTKDDDINAVTWGVFPGEEILQPTIVEKVSFLAWKDEVYRL 550
[110][TOP]
>UniRef100_C5DIA7 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5DIA7_LACTC
Length = 660
Score = 139 bits (349), Expect = 2e-31
Identities = 74/177 (41%), Positives = 106/177 (59%), Gaps = 3/177 (1%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
K KK + W P S +D++ F G+L++ PWS+L GL ET +I E+L ++N
Sbjct: 441 KVSSKKAYEIWGQP-SSTDDIKTLFIRYLEGSLEALPWSDL-GLSAETALIQEELIQLNE 498
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP--- 183
G+L++ SQP+ N+ S GWG PGGYVYQK+++E F K + + L K K P
Sbjct: 499 RGYLSLASQPATNSTPSTDKIFGWGPPGGYVYQKSFVEMFVHKQQWE-LEIKPKLEPLGS 557
Query: 182 SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
++Y + +E + +N S + VTWGVFP EV+Q TIV+ SFK W+DEAF IW
Sbjct: 558 KVSYYVGDSAETFYTNLDSSCSSVVTWGVFPNSEVLQTTIVEEESFKAWRDEAFSIW 614
[111][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 139 bits (349), Expect = 2e-31
Identities = 76/180 (42%), Positives = 102/180 (56%), Gaps = 11/180 (6%)
Frame = -1
Query: 521 KKLQQEWVVP--LKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNG 348
KK W P LK D+ F G L S PWS+ + +++II + L +N G
Sbjct: 375 KKAFDLWGHPGTLKQFSDIIISFLS---GKLNSLPWSD-SAIGQDSEIIVDNLIALNKKG 430
Query: 347 FLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF------ 186
F T+NSQPS+NA KS+ GWG GYVYQK YLEFF KD + L+ + +
Sbjct: 431 FFTLNSQPSLNAIKSNDKVYGWGPKNGYVYQKQYLEFFVHKDIIPALLHQIDNYNRGQGD 490
Query: 185 ---PSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
+TY AV++ SNT + D+NAVTWGVFP +E++QPTIV+ SF WKDE + +
Sbjct: 491 SNSSVLTYYAVDQKGKLFSNTKDDDINAVTWGVFPGEEILQPTIVEKVSFLAWKDEVYRL 550
[112][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 137 bits (346), Expect = 4e-31
Identities = 71/156 (45%), Positives = 91/156 (58%), Gaps = 1/156 (0%)
Frame = -1
Query: 476 DVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDS 297
DV E F G++ PW E LQPE+ +I QL K+N GFLT+NSQP V+ S
Sbjct: 385 DVYEVFARYVEGSVPHIPWCETP-LQPESFLIQPQLAKLNRYGFLTVNSQPPVDGLPSCH 443
Query: 296 PAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKS-ENWVSNTGESD 120
GWGG GG VYQKAY E F S K + L + PS+ AVN + + E
Sbjct: 444 KVFGWGGKGGRVYQKAYFECFVSPSKANRLTQMVTDHPSLNMYAVNNAGQELRVGVEEGG 503
Query: 119 VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
V A+TWGVFP +E++QPTI DP +F +W +EAF +W
Sbjct: 504 VTALTWGVFPNREILQPTIFDPDTFLIWAEEAFSLW 539
[113][TOP]
>UniRef100_A7TRT4 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TRT4_VANPO
Length = 645
Score = 137 bits (345), Expect = 5e-31
Identities = 74/173 (42%), Positives = 104/173 (60%), Gaps = 3/173 (1%)
Frame = -1
Query: 521 KKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFL 342
KK W P KS+ D++ F + G++ + PW +L GL PET +I E+L ++N G+L
Sbjct: 429 KKAYDLWGTP-KSVIDLKSVFIKYLEGSISALPWCDL-GLSPETALIQEELIQLNQRGYL 486
Query: 341 TINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE-KSKAFP--SITY 171
T+ SQP+ NA+ S GWG GYVYQKA++E F K + + +V+ K +P +Y
Sbjct: 487 TLASQPATNASPSTDKIFGWGPKNGYVYQKAFVEMFILKKQWEAIVKPKLDHYPRGKFSY 546
Query: 170 MAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
+ S ++ SN + N VTWGVFP VIQ TIV+ SFK W+DEAF IW
Sbjct: 547 YVGDSSGSFESNLETNSSNVVTWGVFPNSPVIQTTIVEEESFKAWRDEAFCIW 599
[114][TOP]
>UniRef100_B6JY06 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6JY06_SCHJY
Length = 626
Score = 136 bits (343), Expect = 8e-31
Identities = 66/164 (40%), Positives = 96/164 (58%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQP 324
W P+ +D+ FK +G + PW + ++ ETK I ++L K+ + T+ SQP
Sbjct: 419 WGYPVDE-DDITNIFKRHVLGETTAIPWID-QPVEAETKTIGDKLAKLIEKKWWTVGSQP 476
Query: 323 SVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENW 144
+VNAA S GWG GG+V+QKA++E F S + L ++ P ITY+A N +
Sbjct: 477 AVNAAPSSHAIFGWGPRGGWVFQKAFVEMFMSTMDFEALAQRLHDNPQITYLAGNNKGEF 536
Query: 143 VSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
+N NAVTWGVFP +E+IQ TI+ P SF+ W+DEA+ IW
Sbjct: 537 KTNASLDSANAVTWGVFPGREIIQSTIIAPVSFQAWRDEAYSIW 580
[115][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 136 bits (342), Expect = 1e-30
Identities = 73/173 (42%), Positives = 103/173 (59%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ + W P KSI D+ F + G L PWS+ + E I ++L ++N
Sbjct: 366 KGTNEQNIKLWGEP-KSIRDLAHIFVKFMQGELARLPWSDTP-ISGEANAIKDKLIELNK 423
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
G TINSQP+VN A+S P GWG G+VYQKAYLE LD L+ + + +T
Sbjct: 424 RGLFTINSQPAVNGARSSHPVYGWGPKNGFVYQKAYLELLVPPYLLDELIARIEKNEDLT 483
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y AV+K+ +NT +S NA+TWG+F +EV+QPTIV+ SF WKDEA+ +
Sbjct: 484 YHAVSKTGELRTNTRDSP-NALTWGIFAGREVVQPTIVETISFLAWKDEAYRL 535
[116][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 136 bits (342), Expect = 1e-30
Identities = 71/175 (40%), Positives = 105/175 (60%), Gaps = 6/175 (3%)
Frame = -1
Query: 521 KKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFL 342
K+ + W P +++ D+ + +K+ PWS+ + +T ++ + L +N G
Sbjct: 377 KRAYELWGCP-QTLNDLSDIIVSYLNNEVKALPWSD-GPIGEDTTVLKDALIALNRKGLF 434
Query: 341 TINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTL---VEKSKA---FPS 180
T+NSQP+++A +S+ GWG G+VYQK YLEF KDKL L VEK A +
Sbjct: 435 TLNSQPALSAVRSNDKLYGWGPKNGFVYQKQYLEFLVRKDKLKELLDIVEKHNAKDTYGL 494
Query: 179 ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
ITY AV+KS N +N+ D+NAVTWGVFP +E++QPTIV+ SF WKDE + +
Sbjct: 495 ITYYAVDKSGNLHTNSKNDDINAVTWGVFPGEEILQPTIVEKVSFLAWKDEVYSL 549
[117][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 135 bits (340), Expect = 2e-30
Identities = 62/132 (46%), Positives = 87/132 (65%), Gaps = 1/132 (0%)
Frame = -1
Query: 425 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 246
PW++ + L ET ++ E+L ++N G LTINSQP++N S P +GWG GGYV+QKAY
Sbjct: 484 PWND-EPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAY 542
Query: 245 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 69
LEFF S++ + L++ K + + Y VN ++N E NAVTWG+FP +E+IQP
Sbjct: 543 LEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQP 602
Query: 68 TIVDPASFKVWK 33
T+VDP SF WK
Sbjct: 603 TVVDPVSFMFWK 614
[118][TOP]
>UniRef100_Q6FNS2 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FNS2_CANGA
Length = 645
Score = 134 bits (338), Expect = 3e-30
Identities = 70/178 (39%), Positives = 105/178 (58%), Gaps = 3/178 (1%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
K +K+ + W P SI D++ F + G+++S PW +L GL PET +I E+L ++N
Sbjct: 425 KVSNKRAYELWGSPT-SIRDLKAVFVKYLEGSIQSLPWCDL-GLSPETALIQEELIQLNY 482
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF---P 183
G+LT+ SQP NA+ S GWG G+VYQKA++E F + + T+++ +
Sbjct: 483 RGYLTLASQPCTNASSSTDKIFGWGPSKGHVYQKAFIEMFVHRQQWKTILKPKLDYYGRR 542
Query: 182 SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWS 9
+Y A + ++ +N N VTWGVFP +VIQ TI++ SFK W+DEAF IWS
Sbjct: 543 KFSYYAGDSKGSFETNLDPHSSNVVTWGVFPNSQVIQTTIIEEESFKAWRDEAFSIWS 600
[119][TOP]
>UniRef100_Q752W6 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q752W6_ASHGO
Length = 635
Score = 134 bits (337), Expect = 4e-30
Identities = 68/176 (38%), Positives = 102/176 (57%), Gaps = 2/176 (1%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
K +KK Q W P ++ D++ F G++++ PW +L GL PET +I E+L +N
Sbjct: 416 KVSNKKAYQIWGYP-STLNDIKSLFIGYLEGSIEALPWCDL-GLSPETALIQEELIGLNQ 473
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP--S 180
GFLT+ SQP+ N+ S GWG PGG VYQKA++E F K + + ++ P
Sbjct: 474 RGFLTLASQPATNSTPSADKIFGWGPPGGVVYQKAFVELFVEKARWEAELKPRLEGPDSK 533
Query: 179 ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
+Y + + ++ SN + VTWGVFP +++Q TI++ SFK W+DEAF IW
Sbjct: 534 FSYYFGDSAGSFASNMAPESSSVVTWGVFPNSQILQTTIIEEESFKAWRDEAFSIW 589
[120][TOP]
>UniRef100_Q0UB79 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UB79_PHANO
Length = 543
Score = 134 bits (337), Expect = 4e-30
Identities = 65/156 (41%), Positives = 96/156 (61%)
Frame = -1
Query: 479 EDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSD 300
+D+ F++ G L++ PWSE GL PET I +QL +N+ G+ T+ SQP+VN +S
Sbjct: 344 QDISALFRKHLEGELEALPWSE-QGLSPETSTIAKQLLALNAKGWWTVASQPAVNGVRST 402
Query: 299 SPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESD 120
P GWG GYV+QK ++EFF + L + A +TY A N + ++ +++ ES
Sbjct: 403 DPVFGWGPKNGYVFQKPFVEFFLPAAEFHALRTRLDAHDQVTYFAGNANGDFEASSEES- 461
Query: 119 VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
VN VTWG F KE++ PTI++ SF+ W +EAF IW
Sbjct: 462 VNPVTWGTFAGKEIVTPTIIEAVSFRSWLEEAFSIW 497
[121][TOP]
>UniRef100_B2WHR5 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WHR5_PYRTR
Length = 653
Score = 134 bits (337), Expect = 4e-30
Identities = 67/164 (40%), Positives = 97/164 (59%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQP 324
W P++ +D+ F+ G+L++ PWSE GL PET I+ QL +N+ G+ T+ SQP
Sbjct: 447 WGYPVEK-KDISTLFRRHIEGDLEAIPWSE-QGLSPETSTISAQLLALNAKGWWTVASQP 504
Query: 323 SVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENW 144
+VN KS P GWG GYV+QK ++EFF + K +A +T+ A N + +
Sbjct: 505 AVNGVKSTDPIFGWGPKNGYVFQKPFVEFFIPAAEFQAFKPKLQAHDQVTWFAGNAAGAF 564
Query: 143 VSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
++ E VN VTWG F KE++ PTI++ SF+ W DEAF IW
Sbjct: 565 EASQ-EDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWLDEAFSIW 607
[122][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 134 bits (336), Expect = 5e-30
Identities = 70/145 (48%), Positives = 90/145 (62%), Gaps = 2/145 (1%)
Frame = -1
Query: 443 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 264
G+LK PWS++ L E + + L ++N + LTINSQP VN A S P +GWG GY
Sbjct: 408 GDLKCLPWSDVP-LHQEADALLDSLIRLNEHLVLTINSQPKVNGAPSADPIVGWGPANGY 466
Query: 263 VYQKAYLEFFCSKDKLDTLVEKSKA-FPSITYMAVNKSENWVSN-TGESDVNAVTWGVFP 90
VYQK YLEF K L A FP++TY AV+ +N SN ++ NAVTWG+FP
Sbjct: 467 VYQKQYLEFLLPKHHLPAFHAALTADFPTLTYFAVDADDNLASNHPDDTQANAVTWGIFP 526
Query: 89 AKEVIQPTIVDPASFKVWKDEAFEI 15
+EV+QPTIV+ ASF WKDE + I
Sbjct: 527 GREVLQPTIVEKASFLAWKDEFYRI 551
[123][TOP]
>UniRef100_Q6CEM7 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CEM7_YARLI
Length = 625
Score = 133 bits (335), Expect = 7e-30
Identities = 70/166 (42%), Positives = 95/166 (57%), Gaps = 1/166 (0%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQP 324
W P+ D+ + F + +G L PWS+ L PET +I EQL ++N G T+ SQP
Sbjct: 416 WGYPVDDA-DLSKLFADTIVGKLPFMPWSD-QTLSPETMLIQEQLMELNQKGIWTVASQP 473
Query: 323 SVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENW 144
+ NA KSD GWG GGYV+QK++ EFF S ++ L A + V KS+
Sbjct: 474 ACNALKSDDNIFGWGPKGGYVFQKSFAEFFISPEQWKKLKPLLDAQEDLVSYYVAKSDKL 533
Query: 143 V-SNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWS 9
V +N E N VTWGVFP +E++Q TI+ SF W++EAF IWS
Sbjct: 534 VDTNVSERASNGVTWGVFPNREIVQTTIIQEDSFDAWREEAFSIWS 579
[124][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 132 bits (333), Expect = 1e-29
Identities = 71/173 (41%), Positives = 98/173 (56%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
KG +++ + W P KS+ D+ F G L PWS+ + E I L +N
Sbjct: 366 KGTNEQNIKLWGEP-KSLRDLTHIFVNFLEGKLARLPWSDTP-ITTEANAIKTSLIDLNQ 423
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT 174
G TINSQP+VN KS P GWG GYVYQKAYLE +D L+ + + +T
Sbjct: 424 KGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNGDLT 483
Query: 173 YMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
Y AV+K+ +NT +S NA+TWG+F +E++QPTIV+ SF WKDEA+ +
Sbjct: 484 YHAVSKTGELRTNTRDSP-NALTWGIFAGREIVQPTIVETVSFLAWKDEAYRL 535
[125][TOP]
>UniRef100_B2B6X0 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B6X0_PODAN
Length = 691
Score = 132 bits (332), Expect = 2e-29
Identities = 69/177 (38%), Positives = 101/177 (57%), Gaps = 13/177 (7%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQP 324
W P ++ ED+ F G L + PWSE +G PET I +QL K+NS G+ ++ SQP
Sbjct: 471 WGTP-RTTEDINNVFIRHLKGELTTIPWSE-EGFSPETDKIRDQLIKLNSKGWWSLASQP 528
Query: 323 SVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSK---AFPSITYMAVNKS 153
+VN +S P GWG G+V+QKA++EFF L +K + + + A+N +
Sbjct: 529 AVNGLRSSDPTFGWGPANGFVFQKAFVEFFIPSADWKVLEQKLRHPDLKDDVCFYAINAA 588
Query: 152 ENWVSN----------TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
++VS+ E+ NAVTWGVFP KE++ PTI++ SF+ W +EAF IW
Sbjct: 589 GDFVSSDTAGSLEAEGEKEASTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIW 645
[126][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 131 bits (330), Expect = 3e-29
Identities = 71/170 (41%), Positives = 97/170 (57%), Gaps = 1/170 (0%)
Frame = -1
Query: 521 KKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFL 342
KK + W P K+IEDV + G +K PWS+ L E I + L +N +
Sbjct: 382 KKSLELWSTP-KTIEDVSQLVISYLTGQIKCLPWSDTS-LDEEIDPILDHLLDLNRKMII 439
Query: 341 TINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAV 162
TINSQP +N +S+ GWG GYVYQK YLEF +K++ L ++ +TY AV
Sbjct: 440 TINSQPQINGIRSNHKVHGWGPKDGYVYQKQYLEFLLPNEKVEKLEKQLAGNEMLTYFAV 499
Query: 161 NKSENWVSNTGE-SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
+ +N SN + S NAVTWG+FP +EV+QPTIV+ SF WK+E + I
Sbjct: 500 DNKDNLKSNHPDGSKANAVTWGIFPGREVLQPTIVEKVSFLAWKEEFYRI 549
[127][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 131 bits (330), Expect = 3e-29
Identities = 73/170 (42%), Positives = 94/170 (55%), Gaps = 4/170 (2%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQP 324
W P K D+ + G LK PW ++ L E QL +N + LT+NSQP
Sbjct: 386 WSTPTK-FSDIAALVIDYLHGKLKCLPWCDV-ALNHEVDTTMPQLLDLNKHMILTLNSQP 443
Query: 323 SVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENW 144
VN A S +GWG GYVYQK YLEF K KL L + PS+TY AV+ ++
Sbjct: 444 RVNGASSADKIVGWGPNNGYVYQKQYLEFLLPKSKLSQLRDFVNDMPSLTYFAVDSADEL 503
Query: 143 VSN-TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI---WSR 6
SN ++ NAVTWG+FP +EV+QPTIV+ SF WK+E F+I W R
Sbjct: 504 HSNHPDDTAANAVTWGIFPGREVLQPTIVEKVSFLAWKEEFFDILDEWKR 553
[128][TOP]
>UniRef100_Q5A5S8 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5A5S8_CANAL
Length = 640
Score = 130 bits (327), Expect = 6e-29
Identities = 67/170 (39%), Positives = 98/170 (57%), Gaps = 5/170 (2%)
Frame = -1
Query: 506 EWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQ 327
+W P +SI D+ + F G + PW++ L PET +I E+L ++N G+ ++ SQ
Sbjct: 426 KWGTP-ESIADLTQVFINYLSGKVDVVPWAD-SSLSPETALIQEELFQLNEKGWFSVASQ 483
Query: 326 PSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEN 147
P+VN KS GWG G +YQK+++E F K+ L+ K + ++TY NK
Sbjct: 484 PAVNGCKSTDNIFGWGPRNGIIYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVGNKDGE 543
Query: 146 WVSN-----TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
SN + NAVTWGVFP+KEV+QPT++D SFK W +EAF +W
Sbjct: 544 IKSNLPIGPNVKLSKNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFLLW 593
[129][TOP]
>UniRef100_C5DPF1 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5DPF1_ZYGRC
Length = 650
Score = 130 bits (327), Expect = 6e-29
Identities = 73/179 (40%), Positives = 103/179 (57%), Gaps = 5/179 (2%)
Frame = -1
Query: 533 KGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS 354
K +KK + W P K+I+D+Q F + G++ + PW +L GL PET +I E+L ++N
Sbjct: 429 KVSNKKAYELWGQP-KTIQDLQIIFIKYLEGSIDALPWCDL-GLSPETALIQEELIQLNE 486
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKD-----KLDTLVEKSKA 189
GFLT+ SQP+ N + S + GWG G VYQKA++E F K+ + +E+
Sbjct: 487 RGFLTLASQPATNGSPSTNKIFGWGPAYGVVYQKAFIEMFVPKNIWENGNMKKAIEQ-YG 545
Query: 188 FPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
+TY A + N+ +N + N VTWGVF +VIQ TIV SFK W DEAF IW
Sbjct: 546 RAKLTYYANDSQGNFETNLESNSSNVVTWGVFSDSQVIQSTIVSEESFKAWSDEAFSIW 604
[130][TOP]
>UniRef100_C4YKV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=C4YKV3_CANAL
Length = 640
Score = 130 bits (327), Expect = 6e-29
Identities = 67/170 (39%), Positives = 98/170 (57%), Gaps = 5/170 (2%)
Frame = -1
Query: 506 EWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQ 327
+W P +SI D+ + F G + PW++ L PET +I E+L ++N G+ ++ SQ
Sbjct: 426 KWGTP-ESIADLTQVFINYLSGKVDVVPWAD-SSLSPETALIQEELFQLNEKGWFSVASQ 483
Query: 326 PSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEN 147
P+VN KS GWG G +YQK+++E F K+ L+ K + ++TY NK
Sbjct: 484 PAVNGCKSTDNIFGWGPRNGIIYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVGNKDGE 543
Query: 146 WVSN-----TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
SN + NAVTWGVFP+KEV+QPT++D SFK W +EAF +W
Sbjct: 544 IKSNLPIGPNVKLSKNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFLLW 593
[131][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 129 bits (325), Expect = 1e-28
Identities = 71/169 (42%), Positives = 95/169 (56%), Gaps = 1/169 (0%)
Frame = -1
Query: 518 KLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLT 339
K + W P SI DV GNLK PWS++ + E I L ++N + +T
Sbjct: 383 KCLELWSTPT-SINDVAFLVINYLNGNLKCLPWSDIT-INDEINPIKAHLIELNQHSIIT 440
Query: 338 INSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVN 159
INSQP VN +S+ GWG GYVYQK YLEF K KL L++ K +TY A++
Sbjct: 441 INSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAID 500
Query: 158 KSENWVSN-TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
+ +SN S NAVTWG+FP +E++QPTIV+ SF WK+E + I
Sbjct: 501 SQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFYHI 549
[132][TOP]
>UniRef100_C5M548 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M548_CANTT
Length = 633
Score = 129 bits (325), Expect = 1e-28
Identities = 68/170 (40%), Positives = 101/170 (59%), Gaps = 5/170 (2%)
Frame = -1
Query: 506 EWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQ 327
+W P ++ +D+ + F + G + PW++ L PET +I E+L ++N G+ ++ SQ
Sbjct: 419 KWGSP-ETTKDLAQIFIDYLSGKIDVIPWAD-QALSPETALIQEELFQLNEKGWFSVASQ 476
Query: 326 PSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEN 147
P+ NA KS GWG G VYQKA++E F KD + L +A SITY A +K+
Sbjct: 477 PAANACKSTDNIFGWGPRNGVVYQKAFVELFMPKDDWNKLKPLVEASDSITYYAADKTNK 536
Query: 146 WVSNT-GESDV----NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
+ D+ NAVTWGVFP+KEV+QPT++D SFK W +E+F +W
Sbjct: 537 IEAKVPAGHDIKLTKNAVTWGVFPSKEVLQPTVIDYESFKAWNEESFLLW 586
[133][TOP]
>UniRef100_B5VIK4 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VIK4_YEAS6
Length = 411
Score = 129 bits (325), Expect = 1e-28
Identities = 71/169 (42%), Positives = 95/169 (56%), Gaps = 1/169 (0%)
Frame = -1
Query: 518 KLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLT 339
K + W P SI DV GNLK PWS++ + E I L ++N + +T
Sbjct: 194 KCLELWSTPT-SINDVAFLVINYLNGNLKCLPWSDIP-INDEINPIKAHLIELNQHSIIT 251
Query: 338 INSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVN 159
INSQP VN +S+ GWG GYVYQK YLEF K KL L++ K +TY A++
Sbjct: 252 INSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAID 311
Query: 158 KSENWVSN-TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
+ +SN S NAVTWG+FP +E++QPTIV+ SF WK+E + I
Sbjct: 312 SQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFYHI 360
[134][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 129 bits (325), Expect = 1e-28
Identities = 71/169 (42%), Positives = 95/169 (56%), Gaps = 1/169 (0%)
Frame = -1
Query: 518 KLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLT 339
K + W P SI DV GNLK PWS++ + E I L ++N + +T
Sbjct: 383 KCLELWSTPT-SINDVAFLVINYLNGNLKCLPWSDIP-INDEINPIKAHLIELNQHSIIT 440
Query: 338 INSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVN 159
INSQP VN +S+ GWG GYVYQK YLEF K KL L++ K +TY A++
Sbjct: 441 INSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAID 500
Query: 158 KSENWVSN-TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
+ +SN S NAVTWG+FP +E++QPTIV+ SF WK+E + I
Sbjct: 501 SQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFYHI 549
[135][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 129 bits (325), Expect = 1e-28
Identities = 71/169 (42%), Positives = 95/169 (56%), Gaps = 1/169 (0%)
Frame = -1
Query: 518 KLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLT 339
K + W P SI DV GNLK PWS++ + E I L ++N + +T
Sbjct: 383 KCLELWSTPT-SINDVAFLVINYLNGNLKCLPWSDIP-INDEINPIKAHLIELNQHSIIT 440
Query: 338 INSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVN 159
INSQP VN +S+ GWG GYVYQK YLEF K KL L++ K +TY A++
Sbjct: 441 INSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAID 500
Query: 158 KSENWVSN-TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
+ +SN S NAVTWG+FP +E++QPTIV+ SF WK+E + I
Sbjct: 501 SQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFYHI 549
[136][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 129 bits (324), Expect = 1e-28
Identities = 72/173 (41%), Positives = 109/173 (63%), Gaps = 6/173 (3%)
Frame = -1
Query: 509 QEWVVPLKSIEDVQEKFKELCIGNLK--SSPWSELDGLQPETKIINEQLGKINSNGFL-- 342
+EW VP+ S D+ F + K ++P+ +L L PE+ +I L +NS
Sbjct: 415 KEWGVPV-STSDLSALFTAYLHSDPKHLTTPFCDLP-LSPESHMILPHLLALNSANVQHW 472
Query: 341 TINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS--ITYM 168
T+ SQP+V+AAKS+ +GWG GGYV+QKA++EFF ++D+++ L EK + IT
Sbjct: 473 TVGSQPAVDAAKSEDEVVGWGPRGGYVFQKAFVEFFVTEDEVNRLKEKVEREGKGLITMY 532
Query: 167 AVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWS 9
A N+ ++ +NT + VNAVTWGVFP +E+ Q TI++ SF WK+EAF+IW+
Sbjct: 533 AANRKGDFKTNTDKDSVNAVTWGVFPGQEIAQSTIIEETSFLAWKEEAFDIWA 585
[137][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 129 bits (323), Expect = 2e-28
Identities = 72/171 (42%), Positives = 96/171 (56%), Gaps = 2/171 (1%)
Frame = -1
Query: 521 KKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFL 342
KK + W P ++++D+ G LK PWS++ L E I + L +N +
Sbjct: 384 KKSIELWSTP-QTLDDMSNLVTSYLEGKLKCLPWSDVP-LNHEVDDILKHLIDLNKHHIF 441
Query: 341 TINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS-ITYMA 165
TINSQP VN S P +GWG GYVYQK YLEF ++KL E + +TY A
Sbjct: 442 TINSQPKVNGKPSTDPVVGWGPTKGYVYQKEYLEFLLPREKLPLFQEICQEHSDHLTYFA 501
Query: 164 VNKSENWVSNTGE-SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
++ +N +N E S NAVTWGVFP E++QPTIV+ ASF WK+E F I
Sbjct: 502 IDSQDNLATNHPEDSRANAVTWGVFPGSEILQPTIVEKASFLAWKEEFFTI 552
[138][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR2_SCHPO
Length = 641
Score = 128 bits (322), Expect = 2e-28
Identities = 61/164 (37%), Positives = 96/164 (58%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQP 324
W P+ D+ F++ + ++ + PW + + ++ ETK I + L K+N N + T+ SQP
Sbjct: 432 WGYPVDE-SDITSLFQKHIMSDISAIPWID-EPVEVETKTIAKYLLKLNGNSWWTVGSQP 489
Query: 323 SVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENW 144
+VN A S P GWG GG V+QKA++E F + L + K P +TY A N +
Sbjct: 490 AVNGAPSADPVFGWGPKGGRVFQKAFVECFVNGKDLKDFITKWHDNPQVTYYAGNNKSEF 549
Query: 143 VSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
++N + +AVTWGV+P +E+IQ TI+ SFK W E+F++W
Sbjct: 550 LTNAPKDGASAVTWGVYPGREIIQSTIIAEVSFKAWLSESFQVW 593
[139][TOP]
>UniRef100_C9S7I3 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S7I3_9PEZI
Length = 312
Score = 127 bits (320), Expect = 4e-28
Identities = 63/130 (48%), Positives = 76/130 (58%)
Frame = -1
Query: 404 LQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSK 225
L E I E L +N G +TINSQP+VN KS GWG GYVYQK+YLE
Sbjct: 115 LTNEADPIREDLIALNKRGIITINSQPAVNGVKSSHAVHGWGPKNGYVYQKSYLEMLVHP 174
Query: 224 DKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASF 45
D ++ + + P +TY AV KS N N NAVTWGVFP KE++QPTIV+ SF
Sbjct: 175 DLYPEIISRIEKHPDMTYYAVTKSGNLKYNAPSDGPNAVTWGVFPGKEIVQPTIVEGISF 234
Query: 44 KVWKDEAFEI 15
WKDEAF +
Sbjct: 235 VAWKDEAFRL 244
[140][TOP]
>UniRef100_C4Y9Q4 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y9Q4_CLAL4
Length = 601
Score = 127 bits (320), Expect = 4e-28
Identities = 66/169 (39%), Positives = 99/169 (58%), Gaps = 5/169 (2%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQP 324
W P +S+ DV F + + S PW + L PET +I EQL ++NS G T+ SQP
Sbjct: 389 WGTP-QSVADVSRVFIDYLSAKISSLPWVSTE-LSPETALIQEQLFELNSRGLFTLASQP 446
Query: 323 SVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSK---DKLDTLVEKSKAFPSITYMAVNKS 153
+V++ S +GWG G ++QK+++EFF K ++L L++K + +ITY N
Sbjct: 447 AVDSCPSSDSILGWGPRNGRIFQKSFVEFFVPKTEWERLLRLMDKDISDKTITYFCGNSK 506
Query: 152 ENWVSNT--GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
+N S A+TWGVFP+KEV+QPT++D SF+ W +EAF +W
Sbjct: 507 GEITTNMPHKSSQRTAITWGVFPSKEVLQPTVIDRQSFQAWNEEAFGLW 555
[141][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 127 bits (318), Expect = 7e-28
Identities = 73/176 (41%), Positives = 97/176 (55%), Gaps = 7/176 (3%)
Frame = -1
Query: 521 KKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWS------ELDGLQPETKIINEQLGKI 360
KK + W P S+ED+ + G LK PWS E+D + PE +N++L
Sbjct: 381 KKSLELWSAP-NSMEDIAQLVINYLRGELKYLPWSDTSLNHEVDDILPELVTLNQKL--- 436
Query: 359 NSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS 180
+TINSQP +N KS P GWG GYVYQK YLEF K+KL L +
Sbjct: 437 ----IITINSQPQLNGVKSSHPVHGWGPRDGYVYQKMYLEFLLPKEKLSKLHDCLVNDVM 492
Query: 179 ITYMAVNKSENWVSNTGE-SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
+TY AV+ + N +N + + NAVTWG+FP +EV+QPTIV+ SF WK E + I
Sbjct: 493 LTYFAVDHNGNLTTNHQDGTRANAVTWGIFPGREVLQPTIVEKVSFLAWKQEFYHI 548
[142][TOP]
>UniRef100_B9WCV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WCV3_CANDC
Length = 640
Score = 127 bits (318), Expect = 7e-28
Identities = 64/170 (37%), Positives = 97/170 (57%), Gaps = 5/170 (2%)
Frame = -1
Query: 506 EWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQ 327
+W P +S+ D+ F G + PW++ L PET +I E+L ++N G+ ++ SQ
Sbjct: 426 KWGTP-ESLADLTRVFINYLSGKVDVIPWAD-SSLSPETALIQEELFQLNEKGWFSVASQ 483
Query: 326 PSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEN 147
P++N KS GWG G +YQK+++E F K+ L+ K + ++TY +K
Sbjct: 484 PAINGCKSTDNIFGWGPRNGTIYQKSFIELFMPKEDWTKLLLKIELDKTVTYYVGDKDGE 543
Query: 146 WVSN-----TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
SN + NAVTWGVFP+KEV+QPT++D SFK W +EAF +W
Sbjct: 544 IRSNLPIGPNAKLSKNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFLLW 593
[143][TOP]
>UniRef100_Q6CR34 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CR34_KLULA
Length = 649
Score = 126 bits (317), Expect = 9e-28
Identities = 65/166 (39%), Positives = 99/166 (59%), Gaps = 2/166 (1%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQP 324
W P+ S+ED++ F G++K+ PWS+L GL ET I E+L ++N G+L++ SQP
Sbjct: 440 WDHPV-SLEDIKNIFIRYLEGSMKALPWSDL-GLSAETAFIQEELIELNQRGYLSLASQP 497
Query: 323 SVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEK--SKAFPSITYMAVNKSE 150
+ N ++S GWG G +YQKA++E F K++ + +++ +Y + +
Sbjct: 498 ATNGSQSTDNIFGWGPANGLIYQKAFVEIFVRKEEWNQVLKPKIESKNGEFSYYLGDYTG 557
Query: 149 NWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
+ +N NAVTWGVFP EV+Q TIV+ SFK W+DEAF IW
Sbjct: 558 YFETNLQPKSSNAVTWGVFPNSEVVQTTIVEEESFKAWRDEAFSIW 603
[144][TOP]
>UniRef100_Q7S2B6 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S2B6_NEUCR
Length = 681
Score = 124 bits (311), Expect = 4e-27
Identities = 72/192 (37%), Positives = 107/192 (55%), Gaps = 25/192 (13%)
Frame = -1
Query: 509 QEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINS 330
Q W P K+ ED+ + F G L + PWSE +G ET+ I + L ++NS G+ ++ S
Sbjct: 447 QLWGSP-KTTEDINKIFIRHLKGELSAIPWSE-EGFNDETEAIRDNLIELNSRGWWSLAS 504
Query: 329 QPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFC-SKD--KLDTLVEKSKAFPSITYMAVN 159
QP+VN +SD GWG G+V+QKA++EFF S D L+ +++ ++ + A N
Sbjct: 505 QPAVNGLRSDDGTFGWGPENGFVFQKAFVEFFIPSADWRVLEAKLKQPDMKDTVCFFATN 564
Query: 158 KSENWVS---------------NTGESD-------VNAVTWGVFPAKEVIQPTIVDPASF 45
+ ++VS T E+D NAVTWGVFP KE++ PTI++ SF
Sbjct: 565 AAGDFVSTDTINFRARMAAEAEGTAEADHRPHEPSTNAVTWGVFPGKEILTPTIIEEVSF 624
Query: 44 KVWKDEAFEIWS 9
+ W +EAF IWS
Sbjct: 625 RAWSEEAFGIWS 636
[145][TOP]
>UniRef100_A5DE00 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DE00_PICGU
Length = 642
Score = 124 bits (311), Expect = 4e-27
Identities = 69/175 (39%), Positives = 100/175 (57%), Gaps = 9/175 (5%)
Frame = -1
Query: 506 EWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQ 327
+W P +S +D+ + F G + PW + L ET +I E+L ++N G+ ++ SQ
Sbjct: 425 KWGTP-ESTKDISKVFLNYLSGKINILPWVDAP-LSAETALIQEELFELNDKGWFSLASQ 482
Query: 326 PSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDT-LVEKSKAF---PSITYMAVN 159
PSVN A+S GWG G+V+QK+++E F K++ T L K K ITY A +
Sbjct: 483 PSVNGARSSDKIFGWGPSNGFVFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDITYYAGD 542
Query: 158 KSENWVSN-----TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWS 9
S SN + NAVTWGVFP++EV+QPTI+D SF+ W +EAF +WS
Sbjct: 543 SSGKIQSNLPVGPDSHNSKNAVTWGVFPSQEVLQPTIIDIESFRAWNEEAFHLWS 597
[146][TOP]
>UniRef100_Q6BM19 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=Q6BM19_DEBHA
Length = 642
Score = 124 bits (310), Expect = 6e-27
Identities = 67/174 (38%), Positives = 98/174 (56%), Gaps = 9/174 (5%)
Frame = -1
Query: 506 EWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQ 327
+W P +S+ ++ + F G + S PW + L PET +I E+L ++N+ G+ ++ SQ
Sbjct: 423 KWGAP-ESVNEIIKVFVSYLSGKIDSLPWVDA-ALSPETALIQEELFEVNNKGWFSLASQ 480
Query: 326 PSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKD----KLDTLVEKSKAFPSITYMAVN 159
P+VN S GWG G +YQKA++E F KD KL ++K +ITY +
Sbjct: 481 PAVNGCLSSDKIFGWGPGNGIIYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTITYYCGD 540
Query: 158 KSENWVSNTG-----ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
SN + NA+TWGVFP+KEV+QPTI+D SFK W +EAF +W
Sbjct: 541 AEGRLTSNLNIDQEHYNSKNAITWGVFPSKEVLQPTIIDLESFKAWNEEAFILW 594
[147][TOP]
>UniRef100_C9S8T9 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S8T9_9PEZI
Length = 670
Score = 124 bits (310), Expect = 6e-27
Identities = 66/171 (38%), Positives = 97/171 (56%), Gaps = 12/171 (7%)
Frame = -1
Query: 488 KSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAA 309
KS D+ F + G L + PWSE +GL PET II EQL ++N+ G+ T+ SQP+VN
Sbjct: 455 KSSVDISTLFIKHIRGELSAIPWSE-EGLSPETNIIQEQLIELNTRGWWTVASQPAVNGV 513
Query: 308 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEK---SKAFPSITYMAVNKSENWVS 138
S GWG G+V+QKA++E F L E+ + ++ + A N + ++ +
Sbjct: 514 PSRDATFGWGPSHGFVFQKAFVELFLPAADWKVLSERLTGPEVEGTVCFYACNGNGDFAT 573
Query: 137 NTGE---------SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
+ + NAVTWGVFP KE+I PTI++ SF+ W +EAF+IW
Sbjct: 574 SDDSGGLVRTAVPASTNAVTWGVFPGKEIITPTIIEEVSFRAWSEEAFKIW 624
[148][TOP]
>UniRef100_UPI00003BE162 hypothetical protein DEHA0F09867g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE162
Length = 642
Score = 123 bits (308), Expect = 1e-26
Identities = 67/174 (38%), Positives = 97/174 (55%), Gaps = 9/174 (5%)
Frame = -1
Query: 506 EWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQ 327
+W P +S+ ++ + F G + S PW + L PET +I E+L ++N+ G+ ++ SQ
Sbjct: 423 KWGAP-ESVNEIIKVFVSYLSGKIDSLPWVDA-ALSPETALIQEELFEVNNKGWFSLASQ 480
Query: 326 PSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKD----KLDTLVEKSKAFPSITYMAVN 159
P+VN S GWG G +YQKA++E F KD KL ++K +ITY +
Sbjct: 481 PAVNGCLSSDKIFGWGPGNGIIYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTITYYCGD 540
Query: 158 KSENWVSNTG-----ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
SN + NA+TWGVFP KEV+QPTI+D SFK W +EAF +W
Sbjct: 541 AEGRLTSNLNIDQEHYNSKNAITWGVFPLKEVLQPTIIDLESFKAWNEEAFILW 594
[149][TOP]
>UniRef100_C7YTQ6 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YTQ6_NECH7
Length = 674
Score = 122 bits (307), Expect = 1e-26
Identities = 67/172 (38%), Positives = 98/172 (56%), Gaps = 13/172 (7%)
Frame = -1
Query: 488 KSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAA 309
K+ +D+ + F + G L + PWSE + L E+ I L ++N G+ T+ SQP+VN
Sbjct: 458 KTRQDINDLFVKHIQGQLSAIPWSE-EELLAESSTIQPHLLRLNQKGWWTVASQPAVNGL 516
Query: 308 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEK---SKAFPSITYMAVNKSENWVS 138
+S GWG P G+V+QK+++EFF + L EK S+ S+ + A N ++VS
Sbjct: 517 RSSDGTFGWGPPNGFVFQKSFVEFFIPSSEWSVLKEKLNSSELCDSVCFYAGNAKGDFVS 576
Query: 137 N------TGES----DVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
+ G S NAVTWGVFP KE+I PTI++ SF+ W +EAF IW
Sbjct: 577 SDKGGHVDGSSGAGPSTNAVTWGVFPGKEIITPTIIEEVSFRAWCEEAFGIW 628
[150][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri NRRL
181 RepID=A1CZX0_NEOFI
Length = 716
Score = 122 bits (307), Expect = 1e-26
Identities = 71/187 (37%), Positives = 102/187 (54%), Gaps = 23/187 (12%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSE------LDGLQPETKIINEQLGK-INSNGF 345
W P+ S ED+ F+ G+L PWSE GL ET++I +L K I+S G+
Sbjct: 471 WGYPV-SREDISALFRRHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLIDSKGW 529
Query: 344 LTINSQPSVNAAKSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSI 177
T+ SQP+VN +SD P GWG PG G+V+QK ++EFFC T+++ A +
Sbjct: 530 WTLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEFFCPSKDFQTVLKPLFAKHGHEKL 589
Query: 176 TYMAVNKSENWVSNT------------GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWK 33
+ A N + S+ ++VNAVTWGVF KE++ PTI++ SF+ W
Sbjct: 590 AWFATNVKGEFESSLPADPAHADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWG 649
Query: 32 DEAFEIW 12
+EAF IW
Sbjct: 650 EEAFRIW 656
[151][TOP]
>UniRef100_C7GU28 Met12p n=2 Tax=Saccharomyces cerevisiae RepID=C7GU28_YEAS2
Length = 657
Score = 122 bits (306), Expect = 2e-26
Identities = 66/173 (38%), Positives = 100/173 (57%), Gaps = 3/173 (1%)
Frame = -1
Query: 518 KLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLT 339
K + W +P K+I D+++ F + G+ + PWS+L GL ET +I E+L ++N G+LT
Sbjct: 440 KALELWGIP-KTIGDLKDIFIKYLEGSTDAIPWSDL-GLSAETALIQEELIQLNYRGYLT 497
Query: 338 INSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKS---KAFPSITYM 168
+ SQP+ NA S GWG G +YQKA++E F + + +T ++ +Y
Sbjct: 498 LASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYY 557
Query: 167 AVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWS 9
A + S ++ +N + VTWGVFP V Q TI++ SFK W+DEAF IWS
Sbjct: 558 AGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS 610
[152][TOP]
>UniRef100_B5VTD9 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VTD9_YEAS6
Length = 657
Score = 122 bits (306), Expect = 2e-26
Identities = 66/173 (38%), Positives = 100/173 (57%), Gaps = 3/173 (1%)
Frame = -1
Query: 518 KLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLT 339
K + W +P K+I D+++ F + G+ + PWS+L GL ET +I E+L ++N G+LT
Sbjct: 440 KALELWGIP-KTIGDLKDIFIKYLEGSTDAIPWSDL-GLSAETALIQEELIQLNYRGYLT 497
Query: 338 INSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKS---KAFPSITYM 168
+ SQP+ NA S GWG G +YQKA++E F + + +T ++ +Y
Sbjct: 498 LASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYY 557
Query: 167 AVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWS 9
A + S ++ +N + VTWGVFP V Q TI++ SFK W+DEAF IWS
Sbjct: 558 AGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS 610
[153][TOP]
>UniRef100_B3LL40 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LL40_YEAS1
Length = 657
Score = 122 bits (306), Expect = 2e-26
Identities = 66/173 (38%), Positives = 100/173 (57%), Gaps = 3/173 (1%)
Frame = -1
Query: 518 KLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLT 339
K + W +P K+I D+++ F + G+ + PWS+L GL ET +I E+L ++N G+LT
Sbjct: 440 KALELWGIP-KTIGDLKDIFIKYLEGSTDAIPWSDL-GLSAETALIQEELIQLNYRGYLT 497
Query: 338 INSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKS---KAFPSITYM 168
+ SQP+ NA S GWG G +YQKA++E F + + +T ++ +Y
Sbjct: 498 LASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYY 557
Query: 167 AVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWS 9
A + S ++ +N + VTWGVFP V Q TI++ SFK W+DEAF IWS
Sbjct: 558 AGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS 610
[154][TOP]
>UniRef100_P46151 Methylenetetrahydrofolate reductase 1 n=1 Tax=Saccharomyces
cerevisiae RepID=MTHR1_YEAST
Length = 657
Score = 122 bits (306), Expect = 2e-26
Identities = 66/173 (38%), Positives = 100/173 (57%), Gaps = 3/173 (1%)
Frame = -1
Query: 518 KLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLT 339
K + W +P K+I D+++ F + G+ + PWS+L GL ET +I E+L ++N G+LT
Sbjct: 440 KALELWGIP-KTIGDLKDIFIKYLEGSTDAIPWSDL-GLSAETALIQEELIQLNYRGYLT 497
Query: 338 INSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKS---KAFPSITYM 168
+ SQP+ NA S GWG G +YQKA++E F + + +T ++ +Y
Sbjct: 498 LASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYY 557
Query: 167 AVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWS 9
A + S ++ +N + VTWGVFP V Q TI++ SFK W+DEAF IWS
Sbjct: 558 AGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS 610
[155][TOP]
>UniRef100_UPI000151A866 hypothetical protein PGUG_01501 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151A866
Length = 642
Score = 122 bits (305), Expect = 2e-26
Identities = 68/174 (39%), Positives = 98/174 (56%), Gaps = 9/174 (5%)
Frame = -1
Query: 506 EWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQ 327
+W P +S +D+ + F G + PW + L ET +I E+L ++N G+ ++ SQ
Sbjct: 425 KWGTP-ESTKDISKVFLNYLSGKINILPWVDAP-LSAETALIQEELFELNDKGWFSLASQ 482
Query: 326 PSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDT-LVEKSKAF---PSITYMAVN 159
PSVN A+S GWG G+V+QK+++E F K++ T L K K ITY A +
Sbjct: 483 PSVNGARSSDKIFGWGPSNGFVFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDITYYAGD 542
Query: 158 KSENWVSN-----TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
S SN + NAVTWGVFP +EV+QPTI+D SF+ W +EAF +W
Sbjct: 543 SSGKIQSNLPVGPDSHNSKNAVTWGVFPLQEVLQPTIIDIESFRAWNEEAFHLW 596
[156][TOP]
>UniRef100_A3LW82 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LW82_PICST
Length = 635
Score = 122 bits (305), Expect = 2e-26
Identities = 68/175 (38%), Positives = 99/175 (56%), Gaps = 10/175 (5%)
Frame = -1
Query: 506 EWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQ 327
+W P +S+ D+ + F G + PW++ L ET +I E+L +N G+ ++ SQ
Sbjct: 418 KWGSP-ESVGDIAKVFMGYLSGKIDILPWTD-SSLSAETTLIQEELFDLNDRGWFSLASQ 475
Query: 326 PSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-----SITYMAV 162
P+VN KS GWG G VYQKA++E F K++ ++ + KS P +ITY
Sbjct: 476 PAVNGCKSTDRIFGWGPKNGIVYQKAFVEIFVPKEQWESEL-KSSLKPHFEEKTITYYVG 534
Query: 161 NKSENWVSNT-----GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
+ N SN + NA+TWGVFP+KEV+QPTI+D SFK W +EAF +W
Sbjct: 535 DAEGNIESNLFVGPDAHNSKNAITWGVFPSKEVLQPTIIDYESFKAWNEEAFLLW 589
[157][TOP]
>UniRef100_C8V780 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5AU15] n=2 Tax=Emericella
nidulans RepID=C8V780_EMENI
Length = 684
Score = 121 bits (304), Expect = 3e-26
Identities = 68/187 (36%), Positives = 101/187 (54%), Gaps = 23/187 (12%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSE------LDGLQPETKIIN-EQLGKINSNGF 345
W P+ S +D+ + F+ G+L PWSE GL ET+ I E L I+ G+
Sbjct: 440 WGYPV-STDDISKLFRRHVSGDLHMVPWSEGGAEENTSGLNAETETIRPELLALIDKKGW 498
Query: 344 LTINSQPSVNAAKSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSI 177
T+ SQP+VN +SD P GWG PG G+V+QK ++EFFC T ++ + +
Sbjct: 499 WTLASQPAVNGVRSDDPIFGWGPPGEGFVFQKPFVEFFCPASDFKTTLKPLLQKHGHEKL 558
Query: 176 TYMAVNKSENWVSNT------------GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWK 33
+ A N + ++ S+ ++VNAVTWGVF KE++ PTI++ SF+ W
Sbjct: 559 AWFATNAAGDFESSLPAETSDTEPVEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWG 618
Query: 32 DEAFEIW 12
DEA+ IW
Sbjct: 619 DEAYRIW 625
[158][TOP]
>UniRef100_A2QUJ5 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QUJ5_ASPNC
Length = 699
Score = 121 bits (304), Expect = 3e-26
Identities = 74/188 (39%), Positives = 102/188 (54%), Gaps = 24/188 (12%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSE------LDGLQPETKIIN-EQLGKINSNGF 345
W P+ ED+ F+ G L PWSE +GL ET II E L I+ G+
Sbjct: 453 WGYPVTR-EDISTLFRRHVSGELHMVPWSEGGAEEDSNGLNAETAIIQPELLTLIDKKGW 511
Query: 344 LTINSQPSVNAAKSDSPAIGWGGPG-GYVYQKAYLEFFC-SKDKLDTL--VEKSKAFPSI 177
T+ SQP++N +SD P GWG PG G+V+QK ++EFFC +KD L L + + +
Sbjct: 512 WTLASQPAINGVRSDDPVFGWGPPGEGFVFQKPFVEFFCPTKDYLTVLKPLLQKHGHEKL 571
Query: 176 TYMAVNKSENWVS-----NTGESD--------VNAVTWGVFPAKEVIQPTIVDPASFKVW 36
+ A N ++ S NT + D VNAVTWGVF KE++ PTI++ SF+ W
Sbjct: 572 AWFATNVKGDFESSLPGPNTDDPDPIDINPANVNAVTWGVFRGKEIVTPTIIEEVSFRAW 631
Query: 35 KDEAFEIW 12
DEA+ IW
Sbjct: 632 GDEAYRIW 639
[159][TOP]
>UniRef100_Q1DT03 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DT03_COCIM
Length = 711
Score = 120 bits (302), Expect = 5e-26
Identities = 74/192 (38%), Positives = 99/192 (51%), Gaps = 36/192 (18%)
Frame = -1
Query: 479 EDVQEKFKELCIGNLKSSPWSE------LDGLQPETKIINEQL-GKINSNGFLTINSQPS 321
ED+ F++ G L + PWSE GL PET I L I G+ TI SQP+
Sbjct: 457 EDINNIFRQHVSGGLHAVPWSEGGAAEETGGLSPETITIRPYLLSLIEKRGWWTIASQPA 516
Query: 320 VNAAKSDSPAIGWGGPG-GYVYQKAYLEFFCSKDK----LDTLVEKSKAFPSITYMAVNK 156
V+ +SD P GWG PG G+V+QKA++EFFCSKD L L+++ + A N
Sbjct: 517 VSGVRSDHPIFGWGPPGEGFVFQKAFVEFFCSKDDYRSHLKPLLQRY-GHDEFAWFATNA 575
Query: 155 SENWVSNTGES------------------------DVNAVTWGVFPAKEVIQPTIVDPAS 48
+ ++ S+T S VNAVTWGVF KE+I PTI++ S
Sbjct: 576 AGDFESSTSSSIPVPTGPVDAVFDDMDSFPSSNSGGVNAVTWGVFRGKEIITPTIIEEVS 635
Query: 47 FKVWKDEAFEIW 12
F+ W +EAF IW
Sbjct: 636 FRAWGEEAFRIW 647
[160][TOP]
>UniRef100_UPI000023F2EE hypothetical protein FG07127.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023F2EE
Length = 672
Score = 120 bits (301), Expect = 6e-26
Identities = 65/177 (36%), Positives = 99/177 (55%), Gaps = 13/177 (7%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQP 324
W P K+ +D+ + F + G L + PWSE + L+ E+ I L ++N G+ T+ SQP
Sbjct: 452 WDYP-KTRQDINDLFVKHIQGELSAIPWSE-EELRAESSTIKPHLLQLNGKGWWTVASQP 509
Query: 323 SVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEK---SKAFPSITYMAVNKS 153
+VN +S GWG P G+V+QK+++EFF ++ + L K S+ + + A N
Sbjct: 510 AVNGLRSSDATFGWGPPNGFVFQKSFVEFFIPANEWEILKAKLVSSELQDYVCFYASNAR 569
Query: 152 ENWVSN----------TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
++VS+ NAVTWGVFP KE+I PTI++ SF+ W +EAF IW
Sbjct: 570 GDYVSSDIGGHVDGSTEASPSTNAVTWGVFPGKEIITPTIIEEVSFRAWCEEAFGIW 626
[161][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 120 bits (301), Expect = 6e-26
Identities = 70/187 (37%), Positives = 101/187 (54%), Gaps = 23/187 (12%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSE------LDGLQPETKIINEQLGK-INSNGF 345
W P+ S ED+ F+ G+L PWSE GL ET++I +L K I+ G+
Sbjct: 444 WGYPV-SREDISALFRHHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLIDGKGW 502
Query: 344 LTINSQPSVNAAKSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSI 177
T+ SQP+VN +SD P GWG PG G+V+QK ++EFFC T+++ A +
Sbjct: 503 WTLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEFFCPSKDFRTVLKPLFAKHGHEKL 562
Query: 176 TYMAVNKSENWVSNT------------GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWK 33
+ A N + S+ ++VNAVTWGVF KE++ PTI++ SF+ W
Sbjct: 563 AWFATNVKGEFESSLPADPAHADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWG 622
Query: 32 DEAFEIW 12
+EAF IW
Sbjct: 623 EEAFRIW 629
[162][TOP]
>UniRef100_C1H0K0 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1H0K0_PARBA
Length = 713
Score = 120 bits (301), Expect = 6e-26
Identities = 77/197 (39%), Positives = 105/197 (53%), Gaps = 30/197 (15%)
Frame = -1
Query: 512 QQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSE------LDGLQPETKIINEQLGK-INS 354
+Q W P S ED+ + F G L PWSE GL ET I E+L + I+
Sbjct: 449 RQLWGYPT-SKEDINKLFHCHVSGELHIVPWSEGGSAEDSGGLNAETATIREELLQLIDG 507
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAF 186
G+ T+ SQP+VN +SD P GWG G G+V+QKA++EFFCS + +++ K
Sbjct: 508 RGWWTLASQPAVNGVRSDHPIFGWGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQ 567
Query: 185 PSITYMAVNKSENWVSN------TGESD-------------VNAVTWGVFPAKEVIQPTI 63
+++ A N S ++ S+ TG D VNAVTWGVF KE+I PTI
Sbjct: 568 DELSWFATNASGDFQSSSSFTGITGLDDAVPDYNGAASSNGVNAVTWGVFKGKEIITPTI 627
Query: 62 VDPASFKVWKDEAFEIW 12
++ SF+ W DEAF IW
Sbjct: 628 IEEVSFRAWGDEAFRIW 644
[163][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 120 bits (301), Expect = 6e-26
Identities = 70/187 (37%), Positives = 101/187 (54%), Gaps = 23/187 (12%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSE------LDGLQPETKIINEQLGK-INSNGF 345
W P+ S ED+ F+ G+L PWSE GL ET++I +L K I+ G+
Sbjct: 444 WGYPV-SREDISALFRRHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLIDGKGW 502
Query: 344 LTINSQPSVNAAKSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSI 177
T+ SQP+VN +SD P GWG PG G+V+QK ++EFFC T+++ A +
Sbjct: 503 WTLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEFFCPSKDFRTVLKPLFAKHGHEKL 562
Query: 176 TYMAVNKSENWVSNT------------GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWK 33
+ A N + S+ ++VNAVTWGVF KE++ PTI++ SF+ W
Sbjct: 563 AWFATNVKGEFESSLPADPAHADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWG 622
Query: 32 DEAFEIW 12
+EAF IW
Sbjct: 623 EEAFRIW 629
[164][TOP]
>UniRef100_C5P4Q4 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5P4Q4_COCP7
Length = 711
Score = 120 bits (300), Expect = 8e-26
Identities = 73/192 (38%), Positives = 99/192 (51%), Gaps = 36/192 (18%)
Frame = -1
Query: 479 EDVQEKFKELCIGNLKSSPWSE------LDGLQPETKIINEQL-GKINSNGFLTINSQPS 321
ED+ F++ G L + PWSE GL PET I L I G+ T+ SQP+
Sbjct: 457 EDINNIFRQHVSGGLHAVPWSEGGAAEETGGLSPETITIRPYLLSLIEKRGWWTLASQPA 516
Query: 320 VNAAKSDSPAIGWGGPG-GYVYQKAYLEFFCSKDK----LDTLVEKSKAFPSITYMAVNK 156
V+ +SD P GWG PG G+V+QKA++EFFCSKD L L+++ + A N
Sbjct: 517 VSGVRSDHPIFGWGPPGEGFVFQKAFVEFFCSKDDYRSHLKPLLQRY-GHDEFAWFATNA 575
Query: 155 SENWVSNTGES------------------------DVNAVTWGVFPAKEVIQPTIVDPAS 48
+ ++ S+T S VNAVTWGVF KE+I PTI++ S
Sbjct: 576 AGDFESSTSSSIPVPTGPVDAVFDDMDSFPSSNSGGVNAVTWGVFRGKEIITPTIIEEVS 635
Query: 47 FKVWKDEAFEIW 12
F+ W +EAF IW
Sbjct: 636 FRAWGEEAFRIW 647
[165][TOP]
>UniRef100_A1C4Z1 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C4Z1_ASPCL
Length = 690
Score = 120 bits (300), Expect = 8e-26
Identities = 69/187 (36%), Positives = 103/187 (55%), Gaps = 23/187 (12%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSE------LDGLQPETKIINEQLGK-INSNGF 345
W P+ S +D+ F+ G L PWSE GL ET++I +L K I+ G+
Sbjct: 445 WGYPV-SRDDISTLFRRHVSGELYIVPWSEGGAEENTSGLNAETEVIRPELLKLIDGKGW 503
Query: 344 LTINSQPSVNAAKSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVEK---SKAFPSI 177
T+ SQP+VN +SD+ GWG PG G+V+QK ++EFFC +T+++ + +
Sbjct: 504 WTLASQPAVNGVRSDNSTFGWGPPGEGFVFQKPFVEFFCPSKDFETVLKPLFANHGHEKL 563
Query: 176 TYMAVNKSENWVSN----TGESD--------VNAVTWGVFPAKEVIQPTIVDPASFKVWK 33
+ A N + S+ T +SD VNAVTWGVF KE++ PTI++ SF+ W
Sbjct: 564 AWFATNAKGEFQSSLPAETADSDALEPNPDNVNAVTWGVFRGKEIVTPTIIEEVSFRAWG 623
Query: 32 DEAFEIW 12
+EA+ IW
Sbjct: 624 EEAYRIW 630
[166][TOP]
>UniRef100_Q2HBA5 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2HBA5_CHAGB
Length = 643
Score = 119 bits (299), Expect = 1e-25
Identities = 64/167 (38%), Positives = 92/167 (55%)
Frame = -1
Query: 512 QQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTIN 333
+Q W P+ S D+ F G L++ PWSE + ET I +QL +NS G+ T+
Sbjct: 450 RQLWGAPV-SPPDISAIFIRHLRGELQTIPWSE-ESFSAETDKIRDQLVALNSKGWWTLA 507
Query: 332 SQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKS 153
SQP+VN +S P GWG G+V+QKA++EFF L ++ +N+
Sbjct: 508 SQPAVNGLRSSDPTFGWGPQNGFVFQKAFVEFFLPLADWAALEKR-----------LNRP 556
Query: 152 ENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
E E+ NAV+WGVFP KE++ PTI++ SF+ W +EAF IW
Sbjct: 557 EMEGRREREASTNAVSWGVFPGKEIVPPTIIEEVSFRAWSEEAFGIW 603
[167][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TTE9_VANPO
Length = 612
Score = 119 bits (298), Expect = 1e-25
Identities = 67/169 (39%), Positives = 93/169 (55%), Gaps = 6/169 (3%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFL-TINSQ 327
W +P SI DV G L+ PWS+ + E +I QL +N + TINSQ
Sbjct: 382 WAMP-SSIRDVAMLVVAYLQGELRCLPWSDTP-VSSEVDVIRRQLIALNEQQLIVTINSQ 439
Query: 326 PSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEK----SKAFPSITYMAVN 159
P VN +S+ GWG GYVYQK YLEF + + + L ++ ++ S+TY+A +
Sbjct: 440 PQVNGLRSNVKGFGWGPSDGYVYQKQYLEFLLPRARFERLQQELSKTNETTSSLTYLAAD 499
Query: 158 KSENWVSNTGE-SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI 15
W SN + + AVTWGVFP +EV+QPTIV+ SF W+DE + I
Sbjct: 500 SHGGWWSNQPDGAKATAVTWGVFPGREVLQPTIVEKISFLAWRDEFYRI 548
[168][TOP]
>UniRef100_A7E9M9 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7E9M9_SCLS1
Length = 663
Score = 119 bits (298), Expect = 1e-25
Identities = 64/159 (40%), Positives = 91/159 (57%), Gaps = 4/159 (2%)
Frame = -1
Query: 476 DVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDS 297
D+ + F G L + PWSE +GL ET I +QL +N G+ T+ SQP+VN KS
Sbjct: 460 DITDIFIRHLEGQLTAIPWSE-EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGVKSTD 518
Query: 296 PAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEK--SKAF-PSITYMAVNKSENWV-SNTG 129
GWG G+V+QKA++E F + L K S A ++++ A N +++ S+
Sbjct: 519 SIFGWGPKNGFVFQKAFVELFLPTSDWEALQAKLTSPALRDTVSFYASNAKGDFISSDEA 578
Query: 128 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
NAVTWG FP KE+I PTI++ SF+ W +EAF IW
Sbjct: 579 IGSTNAVTWGAFPGKEIITPTIIEEVSFRAWAEEAFGIW 617
[169][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 119 bits (297), Expect = 2e-25
Identities = 65/178 (36%), Positives = 99/178 (55%), Gaps = 13/178 (7%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKIN----------S 354
W P+ S+ D+ F + PW + L ET I + L +N
Sbjct: 464 WGHPV-SLTDISRIFGFYLEEKISCIPWCDAP-LMNETLQIRDHLLTLNRLAENASQSAG 521
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCS---KDKLDTLVEKSKAFP 183
G+ ++ SQP+V+ A S P +G+G PGG+V+QK+++E F S KD+L ++ A
Sbjct: 522 KGWWSVGSQPAVDGAPSTDPIVGFGPPGGFVFQKSFVELFVSSSDKDRLVARIDALGASA 581
Query: 182 SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWS 9
ITY A N ++ SN G+ + N VTW VFP KE++Q TI++ SF+ W++EAFEIW+
Sbjct: 582 PITYFAGNAKGDFQSNLGDEEANTVTWAVFPGKEIVQSTIIERQSFEAWREEAFEIWA 639
[170][TOP]
>UniRef100_Q2UA39 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus oryzae
RepID=Q2UA39_ASPOR
Length = 690
Score = 119 bits (297), Expect = 2e-25
Identities = 76/188 (40%), Positives = 103/188 (54%), Gaps = 24/188 (12%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSE------LDGLQPETKIIN-EQLGKINSNGF 345
W P+ S ED+ F G L PWSE GL ET++I E L I+ NG+
Sbjct: 444 WGFPV-SHEDISALFHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPELLQLIDGNGW 502
Query: 344 LTINSQPSVNAAKSDSPAIGWGGPG-GYVYQKAYLEFFC-SKDK---LDTLVEKSKAFPS 180
T+ SQP+VN +SD P GWG P G+V+QK ++EFFC SKD L L++K
Sbjct: 503 WTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLLQKH-GHEK 561
Query: 179 ITYMAVNKSENWVSN----TGESD--------VNAVTWGVFPAKEVIQPTIVDPASFKVW 36
+ + A N ++ S+ T ++D VN VTWGVF KE++ PTI++ SF+ W
Sbjct: 562 LAWFAANVKGDFESSLPAQTSDADPIEMNPNNVNCVTWGVFRGKEIVTPTIIEEVSFRAW 621
Query: 35 KDEAFEIW 12
DEAF IW
Sbjct: 622 GDEAFRIW 629
[171][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 119 bits (297), Expect = 2e-25
Identities = 72/199 (36%), Positives = 99/199 (49%), Gaps = 35/199 (17%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSE-----LDGLQPETKIINEQLGK-INSNGFL 342
W P S ED+ F+ L G L + PWSE GL PET I +L K + G+
Sbjct: 410 WGTPT-SREDISNIFRRLLSGELHAVPWSEGGAGEEGGLNPETATIRTELLKLVEGRGWW 468
Query: 341 TINSQPSVNAAKSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSIT 174
T+ SQPSVN ++D P GWG G G+V+QKA++EFFC D + ++ S
Sbjct: 469 TLASQPSVNGVRNDHPIFGWGPRGEGFVFQKAFVEFFCPGDDFHSKLKPLLNSYGHDEFA 528
Query: 173 YMAVNKSENWVSNTG-------------------------ESDVNAVTWGVFPAKEVIQP 69
+ A+N ++ S+T VNAVTWGVF KE++ P
Sbjct: 529 WFAMNAKGDFQSSTSPEPPASPPTDSTEPLFDTDPLTDMDNGSVNAVTWGVFRGKEIVTP 588
Query: 68 TIVDPASFKVWKDEAFEIW 12
TI++ SF+ W +EAF IW
Sbjct: 589 TIIEAVSFRAWGEEAFGIW 607
[172][TOP]
>UniRef100_B8NQE8 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus flavus
NRRL3357 RepID=B8NQE8_ASPFN
Length = 738
Score = 119 bits (297), Expect = 2e-25
Identities = 76/188 (40%), Positives = 103/188 (54%), Gaps = 24/188 (12%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSE------LDGLQPETKIIN-EQLGKINSNGF 345
W P+ S ED+ F G L PWSE GL ET++I E L I+ NG+
Sbjct: 492 WGFPV-SHEDISALFHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPELLQLIDGNGW 550
Query: 344 LTINSQPSVNAAKSDSPAIGWGGPG-GYVYQKAYLEFFC-SKDK---LDTLVEKSKAFPS 180
T+ SQP+VN +SD P GWG P G+V+QK ++EFFC SKD L L++K
Sbjct: 551 WTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLLQKH-GHEK 609
Query: 179 ITYMAVNKSENWVSN----TGESD--------VNAVTWGVFPAKEVIQPTIVDPASFKVW 36
+ + A N ++ S+ T ++D VN VTWGVF KE++ PTI++ SF+ W
Sbjct: 610 LAWFAANVKGDFESSLPAQTSDADPIEMNPNNVNCVTWGVFRGKEIVTPTIIEEVSFRAW 669
Query: 35 KDEAFEIW 12
DEAF IW
Sbjct: 670 GDEAFRIW 677
[173][TOP]
>UniRef100_A6RQJ7 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6RQJ7_BOTFB
Length = 663
Score = 119 bits (297), Expect = 2e-25
Identities = 63/159 (39%), Positives = 90/159 (56%), Gaps = 4/159 (2%)
Frame = -1
Query: 476 DVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDS 297
D+ + F G L + PWSE +GL ET I +QL +N G+ T+ SQP+VN KS
Sbjct: 460 DITDIFIRHLEGQLTAIPWSE-EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGLKSSD 518
Query: 296 PAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSENWV-SNTG 129
GWG G+V+QKA++E F TL K + ++++ A N +++ S+
Sbjct: 519 SIFGWGPKNGFVFQKAFVELFIPVADWKTLHAKLTSPDLCDTVSFYASNAKGDFISSDEA 578
Query: 128 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
NAVTWG FP KE+I PTI++ SF+ W +EAF IW
Sbjct: 579 VGSTNAVTWGAFPGKEIITPTIIEEVSFRAWAEEAFGIW 617
[174][TOP]
>UniRef100_C5GI01 Methylenetetrahydrofolate reductase n=2 Tax=Ajellomyces dermatitidis
RepID=C5GI01_AJEDR
Length = 713
Score = 118 bits (296), Expect = 2e-25
Identities = 68/190 (35%), Positives = 102/190 (53%), Gaps = 34/190 (17%)
Frame = -1
Query: 479 EDVQEKFKELCIGNLKSSPWSE-----LDGLQPETKIINEQLGK-INSNGFLTINSQPSV 318
ED+ F+ G+L PWSE GL ET I ++L + IN G+ T+ SQP+V
Sbjct: 456 EDINTIFQRHVSGDLHIVPWSEGGTQDTGGLNAETATIRDELLQLINGRGWWTLASQPAV 515
Query: 317 NAAKSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSE 150
N ++D P GWG G G+V+QKA++EFFC+ L T+++ ++ + + A N +
Sbjct: 516 NGVRNDHPIFGWGPRGEGFVFQKAFVEFFCTAHDLKTILKPIFENHGHDELAWFATNAAG 575
Query: 149 NWVSNTGESD------------------------VNAVTWGVFPAKEVIQPTIVDPASFK 42
++ S++ +D VNAVTWGVF KE++ PTI++ SF+
Sbjct: 576 DFESSSPPTDDSANDYSGPVDVYLDSNATAGGTGVNAVTWGVFRGKEIVTPTIIEEVSFR 635
Query: 41 VWKDEAFEIW 12
W DEAF IW
Sbjct: 636 AWGDEAFRIW 645
[175][TOP]
>UniRef100_C4R2L4 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2L4_PICPG
Length = 596
Score = 118 bits (295), Expect = 3e-25
Identities = 63/166 (37%), Positives = 95/166 (57%), Gaps = 2/166 (1%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQP 324
W P+ ++D+ + F + + PWSEL GL PET +I E+L ++N TI+SQP
Sbjct: 386 WGYPV-DLDDITKIFIAYLSNRITALPWSEL-GLNPETGLIQEELIQLNEKHMFTISSQP 443
Query: 323 SVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKL-DTLVEKSKAFPSITYMAVNKSEN 147
S N KS GWG GYVYQKA++E F +K + + ++ + S+T+ + +
Sbjct: 444 SANGVKSTDKLFGWGPSEGYVYQKAFVEVFINKKQWNEEILPNLQGHKSVTWYLGDCNNA 503
Query: 146 WVSNTG-ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
+ +N N+VTWG FP KE++Q TI+ SF+ W +EAF IW
Sbjct: 504 FDTNIKIPLSSNSVTWGCFPDKEIVQTTIIGEESFQAWNEEAFNIW 549
[176][TOP]
>UniRef100_Q0CE17 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CE17_ASPTN
Length = 696
Score = 117 bits (294), Expect = 4e-25
Identities = 69/187 (36%), Positives = 100/187 (53%), Gaps = 23/187 (12%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSE------LDGLQPETKIIN-EQLGKINSNGF 345
W P+ +D+ F+ G L PWSE GL PET+ I E L I+ G+
Sbjct: 452 WGYPVTR-DDINTLFRRHVSGELHMVPWSEGGAEEGSGGLNPETETIRPELLQLIDGKGW 510
Query: 344 LTINSQPSVNAAKSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSI 177
T+ SQP+VN +SD P GWG P G+V+QK ++EFFC T ++ + +
Sbjct: 511 WTLASQPAVNGVRSDDPIFGWGPPREGFVFQKPFVEFFCPTKDYQTALKPMLQKHGHEKL 570
Query: 176 TYMAVNKSENWVSN----TGESD--------VNAVTWGVFPAKEVIQPTIVDPASFKVWK 33
+ A N + ++ S+ T ++D VNAVTWGVF KE++ PTI++ SF+ W
Sbjct: 571 AWFATNANGDFESSLPAQTSDADPIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWG 630
Query: 32 DEAFEIW 12
DEA+ IW
Sbjct: 631 DEAYRIW 637
[177][TOP]
>UniRef100_C1GJU2 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1GJU2_PARBD
Length = 712
Score = 117 bits (294), Expect = 4e-25
Identities = 76/197 (38%), Positives = 104/197 (52%), Gaps = 30/197 (15%)
Frame = -1
Query: 512 QQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSE------LDGLQPETKIINEQLGK-INS 354
+Q W P S ED+ + F G L PWSE GL ET I E+L + I+
Sbjct: 449 RQLWGYPT-SREDINKLFHCHVSGELHIVPWSEGGSAEDSGGLNAETATIREELLQLIDG 507
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAF 186
G+ T+ SQP+VN +SD P GWG G G+V+QKA++EFFCS + +++ K
Sbjct: 508 RGWWTLASQPAVNGVRSDHPIFGWGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQ 567
Query: 185 PSITYMAVNKSENWVSN------TGESD-------------VNAVTWGVFPAKEVIQPTI 63
+++ A N S ++ S+ TG D VNAVTWGVF KE+I PTI
Sbjct: 568 DELSWFATNASGDFQSSSSFTGTTGLDDAVPDYNGAASSNGVNAVTWGVFKGKEIITPTI 627
Query: 62 VDPASFKVWKDEAFEIW 12
++ SF+ W EAF IW
Sbjct: 628 IEEVSFRAWGHEAFRIW 644
[178][TOP]
>UniRef100_C0S8C4 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0S8C4_PARBP
Length = 712
Score = 117 bits (294), Expect = 4e-25
Identities = 76/197 (38%), Positives = 104/197 (52%), Gaps = 30/197 (15%)
Frame = -1
Query: 512 QQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSE------LDGLQPETKIINEQLGK-INS 354
+Q W P S ED+ + F G L PWSE GL ET I E+L + I+
Sbjct: 449 RQLWGYPT-SREDINKLFHCHVSGELHIVPWSEGGSAEDSGGLNAETATIREELLQLIDG 507
Query: 353 NGFLTINSQPSVNAAKSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAF 186
G+ T+ SQP+VN +SD P GWG G G+V+QKA++EFFCS + +++ K
Sbjct: 508 RGWWTLASQPAVNGVRSDHPIFGWGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQ 567
Query: 185 PSITYMAVNKSENWVSN------TGESD-------------VNAVTWGVFPAKEVIQPTI 63
+++ A N S ++ S+ TG D VNAVTWGVF KE+I PTI
Sbjct: 568 DELSWFATNASGDFQSSSSFTGTTGLDDAVPDYSGAASSNGVNAVTWGVFKGKEIITPTI 627
Query: 62 VDPASFKVWKDEAFEIW 12
++ SF+ W EAF IW
Sbjct: 628 IEEVSFRAWGHEAFRIW 644
[179][TOP]
>UniRef100_A5DZ35 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DZ35_LODEL
Length = 622
Score = 116 bits (290), Expect = 1e-24
Identities = 65/170 (38%), Positives = 97/170 (57%), Gaps = 5/170 (2%)
Frame = -1
Query: 506 EWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQ 327
+W P +I+++ + F + G + PW++ L PET +I E+L ++N G+ ++ SQ
Sbjct: 411 KWGSPT-NIKELGQVFVDYLSGKIDVVPWADTS-LSPETALIQEELFELNQKGWFSVASQ 468
Query: 326 PSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEN 147
P+VN +S+ GWG G VYQK+++E F L K + + TY +KS
Sbjct: 469 PAVNGCRSNDNVFGWGPGNGVVYQKSFVELFIPAKDWKEL--KPRLDDATTYYVGDKSGR 526
Query: 146 WVSN--TGESD---VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
+ T ES NAVTWGVFP KEV+QPT++D SFK W +EAF +W
Sbjct: 527 IELSLFTNESTRHLKNAVTWGVFPLKEVVQPTVIDYESFKAWNEEAFLLW 576
[180][TOP]
>UniRef100_C0NTN2 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NTN2_AJECG
Length = 713
Score = 115 bits (287), Expect = 3e-24
Identities = 65/190 (34%), Positives = 100/190 (52%), Gaps = 34/190 (17%)
Frame = -1
Query: 479 EDVQEKFKELCIGNLKSSPWSE-----LDGLQPETKIINEQLGK-INSNGFLTINSQPSV 318
+D+ F+ G L PWSE GL ET I ++L + IN G+ T+ SQP+V
Sbjct: 456 QDINNIFQRHVSGELHLVPWSEGGAQDTGGLNAETATIRDELLQLINGRGWWTLASQPAV 515
Query: 317 NAAKSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSE 150
N ++D P GWG G G+V+QKA++EFFC +++++ +S + + A N +
Sbjct: 516 NGVRNDHPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNAAG 575
Query: 149 NWVSNT------------------------GESDVNAVTWGVFPAKEVIQPTIVDPASFK 42
+++S++ G + V AVTWGVF KE++ PTI++ SF+
Sbjct: 576 DFMSSSPATDATTEDSSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFR 635
Query: 41 VWKDEAFEIW 12
W DEAF IW
Sbjct: 636 AWGDEAFRIW 645
[181][TOP]
>UniRef100_C6HED8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6HED8_AJECH
Length = 713
Score = 114 bits (286), Expect = 3e-24
Identities = 65/190 (34%), Positives = 100/190 (52%), Gaps = 34/190 (17%)
Frame = -1
Query: 479 EDVQEKFKELCIGNLKSSPWSE-----LDGLQPETKIINEQLGK-INSNGFLTINSQPSV 318
+D+ F+ G L PWSE GL ET I ++L + IN G+ T+ SQP+V
Sbjct: 456 QDINNIFQRHVSGELHLVPWSEGGAQDTGGLNAETATIRDELLQLINGRGWWTLASQPAV 515
Query: 317 NAAKSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSE 150
N ++D P GWG G G+V+QKA++EFFC +++++ +S + + A N +
Sbjct: 516 NGVRNDHPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNVAG 575
Query: 149 NWVSNT------------------------GESDVNAVTWGVFPAKEVIQPTIVDPASFK 42
+++S++ G + V AVTWGVF KE++ PTI++ SF+
Sbjct: 576 DFMSSSPATDATTEDSSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFR 635
Query: 41 VWKDEAFEIW 12
W DEAF IW
Sbjct: 636 AWGDEAFRIW 645
[182][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NEV2_COPC7
Length = 617
Score = 114 bits (286), Expect = 3e-24
Identities = 60/169 (35%), Positives = 93/169 (55%), Gaps = 2/169 (1%)
Frame = -1
Query: 509 QEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINS 330
Q+W P K+ +D+ F + +P+S + L PE+ I L ++ G+ T+ S
Sbjct: 400 QQWGYP-KTFDDLTRIFLAHLHSEIPITPFSPTE-LCPESITILPHLERLTKRGWWTVGS 457
Query: 329 QPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS--ITYMAVNK 156
QP+V+ S GWG GYV+QK ++EFFC ++ + ++ K + + Y N
Sbjct: 458 QPAVDGISSSDETFGWGPRAGYVFQKGFVEFFCDFHDVEAIEQRIKQRGAGWVHYFMANN 517
Query: 155 SENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWS 9
+ SN E NAVTWGVFP +E+ Q TI++ SF WKDEA++IW+
Sbjct: 518 NGECRSNVPEDGRNAVTWGVFPGQEIQQTTIIEKESFLTWKDEAYDIWN 566
[183][TOP]
>UniRef100_A6QT35 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6QT35_AJECN
Length = 712
Score = 114 bits (286), Expect = 3e-24
Identities = 65/190 (34%), Positives = 99/190 (52%), Gaps = 34/190 (17%)
Frame = -1
Query: 479 EDVQEKFKELCIGNLKSSPWSE-----LDGLQPETKIINEQL-GKINSNGFLTINSQPSV 318
+D+ F+ G L PWSE GL ET I ++L IN G+ T+ SQP+V
Sbjct: 455 QDINNIFQRHVSGELHLVPWSEGGAQDTGGLNAETATIRDELLHLINGRGWWTLASQPAV 514
Query: 317 NAAKSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSE 150
N ++D P GWG G G+V+QKA++EFFC +++++ +S + + A N +
Sbjct: 515 NGVRNDHPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNAAG 574
Query: 149 NWVSNT------------------------GESDVNAVTWGVFPAKEVIQPTIVDPASFK 42
+++S++ G + V AVTWGVF KE++ PTI++ SF+
Sbjct: 575 DFMSSSPATDAATEDFSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFR 634
Query: 41 VWKDEAFEIW 12
W DEAF IW
Sbjct: 635 AWGDEAFRIW 644
[184][TOP]
>UniRef100_A4RH85 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RH85_MAGGR
Length = 662
Score = 114 bits (286), Expect = 3e-24
Identities = 67/190 (35%), Positives = 96/190 (50%), Gaps = 23/190 (12%)
Frame = -1
Query: 509 QEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINS 330
Q W P ++EDV F G L + PWSE + ET+ I + L +NS G+ T+ S
Sbjct: 430 QLWGRPA-TVEDVSNIFMRHLRGALPAIPWSE-EEFNAETETIRDTLLALNSRGWWTVAS 487
Query: 329 QPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT-YMAVNKS 153
QP+VN +S+ GWG G+V+QKA++E F L EK + + + A N
Sbjct: 488 QPAVNGLRSNDRTFGWGPQNGFVFQKAFVEMFLPSKDWKALREKLLSEKDVVCFYASNAK 547
Query: 152 ENWVSNTGESDV----------------------NAVTWGVFPAKEVIQPTIVDPASFKV 39
++ S+ G D NAVTWGVFP KE++ PTI++ SF+
Sbjct: 548 GDFESSDGGGDAPDGAPTGNGFADEQPLPSGSSTNAVTWGVFPGKEIVTPTIIEEVSFRA 607
Query: 38 WKDEAFEIWS 9
W +EAF IW+
Sbjct: 608 WSEEAFGIWA 617
[185][TOP]
>UniRef100_C4JM22 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii 1704
RepID=C4JM22_UNCRE
Length = 709
Score = 114 bits (285), Expect = 4e-24
Identities = 71/199 (35%), Positives = 100/199 (50%), Gaps = 35/199 (17%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSE------LDGLQPETKIINEQL-GKINSNGF 345
W P S ED+ + F+ G L + PWSE GL PET I L I+ G+
Sbjct: 448 WGFPT-SREDINQIFRRHVSGALHAVPWSEGGAAEESGGLNPETATIRPYLLDLIDKRGW 506
Query: 344 LTINSQPSVNAAKSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSI 177
T+ SQP+VN +SD GWG PG G+V+QKA++EFFCS + + ++ +
Sbjct: 507 WTLASQPAVNGVRSDDTTFGWGPPGEGFVFQKAFVEFFCSSNDYRSYLKPLLQRYGHDEF 566
Query: 176 TYMAVNKSENWVSNTGES------------------------DVNAVTWGVFPAKEVIQP 69
+ A N + ++ ++T S VNAVTWGVF KE+I P
Sbjct: 567 AWFATNAAGDFEASTPPSAHSPTEPVDAGFEDPSSPAASNPGGVNAVTWGVFRGKEIITP 626
Query: 68 TIVDPASFKVWKDEAFEIW 12
TI++ SF+ W +EAF IW
Sbjct: 627 TIIEEVSFRAWGEEAFRIW 645
[186][TOP]
>UniRef100_Q497H7 Mthfr protein (Fragment) n=2 Tax=Mus musculus RepID=Q497H7_MOUSE
Length = 166
Score = 113 bits (282), Expect = 1e-23
Identities = 50/102 (49%), Positives = 68/102 (66%), Gaps = 1/102 (0%)
Frame = -1
Query: 314 AAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVS 138
A S P +GWG GGYV+QKAYLEFF S++ ++ L++ K + + Y V+ ++
Sbjct: 1 AKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENIT 60
Query: 137 NTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
N E NAVTWG+FP +E+IQPT+VDP SF WKDEAF +W
Sbjct: 61 NAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALW 102
[187][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 112 bits (281), Expect = 1e-23
Identities = 62/170 (36%), Positives = 94/170 (55%), Gaps = 4/170 (2%)
Frame = -1
Query: 506 EWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQ 327
+W P KS++D+ + F + ++P+S L E+ +I L ++ + T+ SQ
Sbjct: 386 QWNNP-KSLDDLTQIFLGHLHAKILTTPFSPTP-LSSESLMILPHLERLTRRSWWTVGSQ 443
Query: 326 PSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSK--AFPSITYMAVNKS 153
P+V+ S +GWG GGYV+QK ++EFFC + +D + + + + Y A N
Sbjct: 444 PAVDGVSSGDKVVGWGPRGGYVFQKGFVEFFCEEKDMDVIERRVERNGHGWVHYFAGNYK 503
Query: 152 ENWV--SNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWS 9
+ SN E NAVTWGVFP +E+ Q TI++ SF WKDEAF IWS
Sbjct: 504 ADGECRSNVPEGGRNAVTWGVFPGQEIAQTTIIEKESFLTWKDEAFSIWS 553
[188][TOP]
>UniRef100_B6HK87 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6HK87_PENCW
Length = 691
Score = 111 bits (277), Expect = 4e-23
Identities = 67/189 (35%), Positives = 100/189 (52%), Gaps = 25/189 (13%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSEL------DGLQPETKIINEQLGK-INSNGF 345
W P+ S +D+ F+ G L PWSE +GL ET++I +L K I+ G+
Sbjct: 443 WGHPVDS-KDMSAIFRRHVSGELHMVPWSEGGAEEDGEGLNAETELIRPELLKLIDGRGW 501
Query: 344 LTINSQPSVNAAKSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSI 177
T+ SQP+VN +D P GWG G+V+QK ++EFFCS + +++ A +
Sbjct: 502 WTLASQPAVNGVHNDHPIFGWGPQREGFVFQKPFVEFFCSSNDYTNILKPLFAKHGHDKL 561
Query: 176 TYMAVNKSENWVSN--------------TGESDVNAVTWGVFPAKEVIQPTIVDPASFKV 39
T+ A N ++ S+ + VNAVTWGVF KE++ PTI++ SF+
Sbjct: 562 TWFATNVKGDFESSLPAQPADMDLDDLGSNPESVNAVTWGVFRGKEIVTPTIIEEVSFRA 621
Query: 38 WKDEAFEIW 12
W +EAF IW
Sbjct: 622 WGEEAFRIW 630
[189][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 104 bits (260), Expect = 4e-21
Identities = 59/172 (34%), Positives = 92/172 (53%), Gaps = 8/172 (4%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS------NGFL 342
W P+ +D+ F G L PW ++ + ET + L +NS +
Sbjct: 372 WGTPVDE-DDISSIFSRFVDGRLACMPWCDIP-VWDETMQLLPALLHLNSPPSAGGKAWW 429
Query: 341 TINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS-ITYMA 165
T+ SQP+V+ S P G+G GGY++QKA++E F +++ + LV+ + + +TY A
Sbjct: 430 TVGSQPAVDGCDSTDPTFGFGPQGGYIFQKAFVELFMNENDKNALVQMIQGSSTPVTYFA 489
Query: 164 VN-KSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIW 12
+ +N + +N VTWGVFP EV Q TI++ ASF+ W+DEAF IW
Sbjct: 490 GKCDPTTFETNLTTNGLNTVTWGVFPGTEVAQSTIIEEASFRAWRDEAFAIW 541
[190][TOP]
>UniRef100_A7S359 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
RepID=A7S359_NEMVE
Length = 102
Score = 102 bits (254), Expect = 2e-20
Identities = 52/102 (50%), Positives = 68/102 (66%)
Frame = -1
Query: 431 SSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQK 252
S PW++ + L ET I E+L NSNG L+INSQPSVNAA S P +GWGG GGY+YQK
Sbjct: 3 SLPWND-EELALETSFIKEKLIHFNSNGILSINSQPSVNAASSTDPLLGWGGEGGYIYQK 61
Query: 251 AYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 126
AYLEFF S + + L+++ K +P + Y VN N + N G+
Sbjct: 62 AYLEFFASPEVVYILLQELKNYPQVNYHVVN---NHLRNLGK 100
[191][TOP]
>UniRef100_B8MDD4 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8MDD4_TALSN
Length = 713
Score = 102 bits (254), Expect = 2e-20
Identities = 71/204 (34%), Positives = 96/204 (47%), Gaps = 37/204 (18%)
Frame = -1
Query: 512 QQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDG-----LQPETKIINEQLGKI-NSN 351
+Q W P+ ED+ F++ G L PWSE L ET+ I QL +I
Sbjct: 451 KQLWGFPVTR-EDIGALFRKHVSGELYIVPWSEGGAAEDANLNAETETIKPQLLQIIEKK 509
Query: 350 GFLTINSQPSVNAAKSDSPAIGWGGPG-GYVYQKAYLEFFC------SKDKLDTLVEKSK 192
+ T+ SQP+VN +SD P GWG PG G+V+QKA++EFFC +K K L S+
Sbjct: 510 NWWTLASQPAVNGVRSDHPVFGWGPPGEGFVFQKAFVEFFCPSSDYQNKVKPTLLKHGSE 569
Query: 191 AF------------------------PSITYMAVNKSENWVSNTGESDVNAVTWGVFPAK 84
F P T AV ++ ES AVTWG F +
Sbjct: 570 EFSWFAINAAGHLESSFLISTSSSPKPEDTSSAVAAADEEPLEIRESTGMAVTWGAFRGR 629
Query: 83 EVIQPTIVDPASFKVWKDEAFEIW 12
E+ PTI++ SF+ W +EAF IW
Sbjct: 630 EITTPTIIEEVSFRAWGEEAFRIW 653
[192][TOP]
>UniRef100_B6QFH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QFH8_PENMQ
Length = 710
Score = 100 bits (250), Expect = 5e-20
Identities = 70/203 (34%), Positives = 98/203 (48%), Gaps = 39/203 (19%)
Frame = -1
Query: 503 WVVPLKSIEDVQEKFKELCIGNLKSSPWSELDG-----LQPETKIINEQLGKI-NSNGFL 342
W P+ ED+ F++ G L PWSE L ET+II QL +I +
Sbjct: 452 WGFPVTR-EDIGTLFRKHVSGELYIVPWSEGGAAEDANLNAETQIIKPQLLQIIEKKNWW 510
Query: 341 TINSQPSVNAAKSDSPAIGWGGPG-GYVYQKAYLEFFC------SKDKLDTLVEKSKAFP 183
T+ SQP+VN +SD P GWG PG G+V+QKA++EFFC +K K L S+ F
Sbjct: 511 TLASQPAVNGVRSDHPVFGWGPPGEGFVFQKAFVEFFCPNADYQNKVKPTLLKHGSEEF- 569
Query: 182 SITYMAVNKSENWVSN--------------------------TGESDVNAVTWGVFPAKE 81
++ A+N + + S+ ES AVTWG F +E
Sbjct: 570 --SWFAINATGHLESSFLLSASSSPKPEDASSTIAADEEPVEVRESKGMAVTWGAFRGRE 627
Query: 80 VIQPTIVDPASFKVWKDEAFEIW 12
+ PTI++ SF+ W +EAF IW
Sbjct: 628 ITTPTIIEEVSFRAWGEEAFRIW 650
[193][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 95.9 bits (237), Expect = 2e-18
Identities = 66/188 (35%), Positives = 94/188 (50%), Gaps = 17/188 (9%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSS-------PWSELDGLQPETKII 381
+ K ++L + W L S E V E F G + PW++ D L PET ++
Sbjct: 403 KSKSPREELLKMWGQELSSEESVFEVFTYYISGEPNPNGHKVTCLPWND-DPLAPETNLL 461
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 201
+L K+N G LTINSQP+VN S P +GWG GYV+QKAYLEFF S + + L++
Sbjct: 462 KSELQKVNKRGILTINSQPNVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEMVTALIK 521
Query: 200 KSKAF-PSITYMAVNKSENW-------VSNTGESDV--NAVTWGVFPAKEVIQPTIVDPA 51
K + P + Y VN ++ S+TG V NA G VI +I D
Sbjct: 522 VLKRYEPRVNYHIVNVHKHTQLLKLLSSSDTGMGPVIQNAQDLGNL---SVIWISITDDE 578
Query: 50 SFKVWKDE 27
+F +W ++
Sbjct: 579 AFALWIEQ 586
[194][TOP]
>UniRef100_A7QB32 Chromosome chr5 scaffold_72, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7QB32_VITVI
Length = 170
Score = 91.7 bits (226), Expect = 3e-17
Identities = 39/64 (60%), Positives = 50/64 (78%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKI 360
RP DKKLQ+EWVVPLKS+ED+Q++F + C G LK+ PW E +GLQP+TKII+E +G I
Sbjct: 18 RPHACDKKLQEEWVVPLKSVEDIQKRFMKFCRGKLKNGPWKEFEGLQPDTKIIDEPIGNI 77
Query: 359 NSNG 348
N G
Sbjct: 78 NLKG 81
[195][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 72.0 bits (175), Expect = 3e-11
Identities = 40/103 (38%), Positives = 54/103 (52%), Gaps = 7/103 (6%)
Frame = -1
Query: 539 RPKGRDKKLQQEWVVPLKSIEDVQEKF-------KELCIGNLKSSPWSELDGLQPETKII 381
+ K + L Q W L S E V E F C + PW++ + L ET ++
Sbjct: 413 KSKSSKEALLQMWGEELLSEESVFEVFTFYITAQSNRCGQKVLCLPWND-EPLAQETNLL 471
Query: 380 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQK 252
++L K+N G LTINSQP++N S P +GWG GGYVYQK
Sbjct: 472 KDELEKVNRRGVLTINSQPNINGKPSTDPIVGWGPAGGYVYQK 514
[196][TOP]
>UniRef100_Q3EAG8 Methylenetetrahydrofolate reductase n=1 Tax=Arabidopsis thaliana
RepID=Q3EAG8_ARATH
Length = 407
Score = 57.4 bits (137), Expect = 7e-07
Identities = 26/27 (96%), Positives = 27/27 (100%)
Frame = -1
Query: 542 ARPKGRDKKLQQEWVVPLKSIEDVQEK 462
ARPKGRDKKLQQEWVVPLKSIEDVQE+
Sbjct: 371 ARPKGRDKKLQQEWVVPLKSIEDVQER 397
[197][TOP]
>UniRef100_Q9SE60-2 Isoform 2 of Methylenetetrahydrofolate reductase 1 n=1
Tax=Arabidopsis thaliana RepID=Q9SE60-2
Length = 421
Score = 56.6 bits (135), Expect = 1e-06
Identities = 26/26 (100%), Positives = 26/26 (100%)
Frame = -1
Query: 542 ARPKGRDKKLQQEWVVPLKSIEDVQE 465
ARPKGRDKKLQQEWVVPLKSIEDVQE
Sbjct: 371 ARPKGRDKKLQQEWVVPLKSIEDVQE 396