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[1][TOP]
>UniRef100_Q9SZJ5 Serine hydroxymethyltransferase, mitochondrial n=1 Tax=Arabidopsis
           thaliana RepID=GLYM_ARATH
          Length = 517

 Score =  329 bits (843), Expect = 1e-88
 Identities = 169/169 (100%), Positives = 169/169 (100%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV
Sbjct: 349 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 408

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ
Sbjct: 409 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 468

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN
Sbjct: 469 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 517

[2][TOP]
>UniRef100_P50433 Serine hydroxymethyltransferase, mitochondrial n=1 Tax=Solanum
           tuberosum RepID=GLYM_SOLTU
          Length = 518

 Score =  288 bits (737), Expect = 3e-76
 Identities = 143/169 (84%), Positives = 159/169 (94%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EY+AYQEQVLSNS+KFAQ L E+GYELVSGGTDNHLVLVN+K KGIDGSRVEKVLEAV
Sbjct: 350 TPEYRAYQEQVLSNSSKFAQALGEKGYELVSGGTDNHLVLVNMKNKGIDGSRVEKVLEAV 409

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGF+EEDF KVA++FD AV IA+KVK+E Q
Sbjct: 410 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFLEEDFVKVADFFDAAVKIAVKVKAETQ 469

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           GTKLKDFV+ +ESS+ I+SEIAKLRH+VEE+AKQFPTIGFEKETMKYKN
Sbjct: 470 GTKLKDFVATLESSAPIKSEIAKLRHDVEEYAKQFPTIGFEKETMKYKN 518

[3][TOP]
>UniRef100_P49357 Serine hydroxymethyltransferase 1, mitochondrial n=1 Tax=Flaveria
           pringlei RepID=GLYM_FLAPR
          Length = 517

 Score =  286 bits (732), Expect = 1e-75
 Identities = 144/169 (85%), Positives = 162/169 (95%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T+EYKAYQEQV+SNSAKFA+TL++ GYELVSGGT+NHLVLVNLK KGIDGS+VEKVLEAV
Sbjct: 350 TAEYKAYQEQVMSNSAKFAETLVKSGYELVSGGTENHLVLVNLKNKGIDGSKVEKVLEAV 409

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVA +FD AV +A+K+K EA+
Sbjct: 410 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAYFFDLAVKLAVKIKGEAK 469

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           GTKLKDFV+AMESS+ IQSEI+KLRH+VEE+AKQFPTIGFEKETMKYKN
Sbjct: 470 GTKLKDFVTAMESSA-IQSEISKLRHDVEEYAKQFPTIGFEKETMKYKN 517

[4][TOP]
>UniRef100_Q7Y1F0 Serine hydroxymethyltransferase n=1 Tax=Oryza sativa Japonica Group
           RepID=Q7Y1F0_ORYSJ
          Length = 557

 Score =  285 bits (728), Expect = 3e-75
 Identities = 142/169 (84%), Positives = 156/169 (92%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EY+AYQEQV+SN AKFAQ+L  +GYELVSGGTDNHLVLVNLK KGIDGSRVEKVLE V
Sbjct: 389 TPEYRAYQEQVMSNCAKFAQSLTAKGYELVSGGTDNHLVLVNLKSKGIDGSRVEKVLENV 448

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVA++FD AV +ALKVK+ A 
Sbjct: 449 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVADFFDAAVNLALKVKAAAG 508

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           GTKLKDFV+ ++S S IQSEIAKLRH+VEE+AKQFPTIGFEKETMKYKN
Sbjct: 509 GTKLKDFVATLQSDSNIQSEIAKLRHDVEEYAKQFPTIGFEKETMKYKN 557

[5][TOP]
>UniRef100_Q10D67 Serine hydroxymethyltransferase n=1 Tax=Oryza sativa Japonica Group
           RepID=Q10D67_ORYSJ
          Length = 464

 Score =  285 bits (728), Expect = 3e-75
 Identities = 142/169 (84%), Positives = 156/169 (92%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EY+AYQEQV+SN AKFAQ+L  +GYELVSGGTDNHLVLVNLK KGIDGSRVEKVLE V
Sbjct: 296 TPEYRAYQEQVMSNCAKFAQSLTAKGYELVSGGTDNHLVLVNLKSKGIDGSRVEKVLENV 355

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVA++FD AV +ALKVK+ A 
Sbjct: 356 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVADFFDAAVNLALKVKAAAG 415

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           GTKLKDFV+ ++S S IQSEIAKLRH+VEE+AKQFPTIGFEKETMKYKN
Sbjct: 416 GTKLKDFVATLQSDSNIQSEIAKLRHDVEEYAKQFPTIGFEKETMKYKN 464

[6][TOP]
>UniRef100_B9FBQ3 Serine hydroxymethyltransferase n=1 Tax=Oryza sativa Japonica Group
           RepID=B9FBQ3_ORYSJ
          Length = 489

 Score =  285 bits (728), Expect = 3e-75
 Identities = 142/169 (84%), Positives = 156/169 (92%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EY+AYQEQV+SN AKFAQ+L  +GYELVSGGTDNHLVLVNLK KGIDGSRVEKVLE V
Sbjct: 321 TPEYRAYQEQVMSNCAKFAQSLTAKGYELVSGGTDNHLVLVNLKSKGIDGSRVEKVLENV 380

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVA++FD AV +ALKVK+ A 
Sbjct: 381 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVADFFDAAVNLALKVKAAAG 440

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           GTKLKDFV+ ++S S IQSEIAKLRH+VEE+AKQFPTIGFEKETMKYKN
Sbjct: 441 GTKLKDFVATLQSDSNIQSEIAKLRHDVEEYAKQFPTIGFEKETMKYKN 489

[7][TOP]
>UniRef100_Q10D68 Serine hydroxymethyltransferase n=3 Tax=Oryza sativa
           RepID=Q10D68_ORYSJ
          Length = 513

 Score =  285 bits (728), Expect = 3e-75
 Identities = 142/169 (84%), Positives = 156/169 (92%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EY+AYQEQV+SN AKFAQ+L  +GYELVSGGTDNHLVLVNLK KGIDGSRVEKVLE V
Sbjct: 345 TPEYRAYQEQVMSNCAKFAQSLTAKGYELVSGGTDNHLVLVNLKSKGIDGSRVEKVLENV 404

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVA++FD AV +ALKVK+ A 
Sbjct: 405 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVADFFDAAVNLALKVKAAAG 464

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           GTKLKDFV+ ++S S IQSEIAKLRH+VEE+AKQFPTIGFEKETMKYKN
Sbjct: 465 GTKLKDFVATLQSDSNIQSEIAKLRHDVEEYAKQFPTIGFEKETMKYKN 513

[8][TOP]
>UniRef100_C6ZJZ0 Serine hydroxymethyltransferase n=1 Tax=Glycine max
           RepID=C6ZJZ0_SOYBN
          Length = 518

 Score =  284 bits (726), Expect = 5e-75
 Identities = 140/169 (82%), Positives = 157/169 (92%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EY+AYQEQVLSNS KFAQ L ERGYELVSGGT+NHLVLVNLK KGIDGSRVEKVLEAV
Sbjct: 350 TPEYRAYQEQVLSNSFKFAQALSERGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAV 409

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDF KVAE+FD AV +A+K+K +++
Sbjct: 410 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEFFDAAVKLAVKIKGQSK 469

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           GTKLKDF++ ++SSST QSEIAKLRH+VE++AKQFPTIGFEK TMKYKN
Sbjct: 470 GTKLKDFLATIQSSSTFQSEIAKLRHDVEDYAKQFPTIGFEKATMKYKN 518

[9][TOP]
>UniRef100_A9YWS0 Serine hydroxymethyltransferase n=1 Tax=Medicago truncatula
           RepID=A9YWS0_MEDTR
          Length = 518

 Score =  283 bits (724), Expect = 8e-75
 Identities = 140/167 (83%), Positives = 155/167 (92%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EYKAYQEQVLSN AKFAQ L E+GYELVSGGT+NHLVLVNLK KGIDGSRVEKVLEAV
Sbjct: 350 TPEYKAYQEQVLSNCAKFAQALSEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAV 409

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDF KVAEYFD +V +ALK+K+E++
Sbjct: 410 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDASVNLALKIKAESK 469

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKY 119
           GTKLKDFV  ++SSS +QSEI+KLRH+VEEFAKQFPTIGFEK +MKY
Sbjct: 470 GTKLKDFVETLQSSSYVQSEISKLRHDVEEFAKQFPTIGFEKSSMKY 516

[10][TOP]
>UniRef100_A6XMY5 Serine hydroxymethyltransferase n=1 Tax=Triticum monococcum
           RepID=A6XMY5_TRIMO
          Length = 510

 Score =  283 bits (723), Expect = 1e-74
 Identities = 138/169 (81%), Positives = 157/169 (92%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EY+AYQEQV+SNSA+FA++L  +GY++VSGGTDNHLVLVNLK KGIDGSRVEKVLE V
Sbjct: 342 TQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENV 401

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVA++FD AV +ALKVK+ A 
Sbjct: 402 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVADFFDSAVNLALKVKAAAA 461

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           GTKLKDFV+ ++S S IQ+EIAKLRH+VEE+AKQFPTIGFEKETMKYKN
Sbjct: 462 GTKLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIGFEKETMKYKN 510

[11][TOP]
>UniRef100_P49358 Serine hydroxymethyltransferase 2, mitochondrial n=1 Tax=Flaveria
           pringlei RepID=GLYN_FLAPR
          Length = 517

 Score =  283 bits (723), Expect = 1e-74
 Identities = 143/169 (84%), Positives = 159/169 (94%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T+EYKAYQEQV+SN AKFA+TL++ GYELVSGGT+NHLVLVNLK KGIDGSRVEKVLEAV
Sbjct: 350 TAEYKAYQEQVMSNCAKFAETLVKSGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAV 409

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVA  FD AV +A+K+K EAQ
Sbjct: 410 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAYLFDLAVKLAVKIKGEAQ 469

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           GTKLKDFV+AM+SS+  QSEI+KLRH+VEE+AKQFPTIGFEKETMKYKN
Sbjct: 470 GTKLKDFVAAMQSSA-FQSEISKLRHDVEEYAKQFPTIGFEKETMKYKN 517

[12][TOP]
>UniRef100_A7R470 Chromosome undetermined scaffold_622, whole genome shotgun sequence
           (Fragment) n=1 Tax=Vitis vinifera RepID=A7R470_VITVI
          Length = 206

 Score =  282 bits (721), Expect = 2e-74
 Identities = 139/169 (82%), Positives = 156/169 (92%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EYKAYQEQVLSN +KFA+TLM++GYELVSGGT+NHLVLVNLK KGIDGSRVEKVLE+V
Sbjct: 38  TPEYKAYQEQVLSNCSKFAETLMKKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLESV 97

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HI +NKNTVPGDVSAMVP GIRMGTPALTSRGFVEEDF KVAEYFD AVT+A+K+K+E  
Sbjct: 98  HIVANKNTVPGDVSAMVPSGIRMGTPALTSRGFVEEDFVKVAEYFDVAVTVAVKIKAETT 157

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           GTKLKDF++ M+SS  +Q EIAKLRHEVE++AKQFPTIGFEKETMKYKN
Sbjct: 158 GTKLKDFLAIMQSSPHLQYEIAKLRHEVEKYAKQFPTIGFEKETMKYKN 206

[13][TOP]
>UniRef100_UPI0001985E8D PREDICTED: hypothetical protein, partial n=1 Tax=Vitis vinifera
            RepID=UPI0001985E8D
          Length = 1004

 Score =  281 bits (719), Expect = 3e-74
 Identities = 138/169 (81%), Positives = 156/169 (92%)
 Frame = -3

Query: 619  TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
            T EYKAYQEQVLSN +KFA+TLM++GYELVS GT+NHLVLVNLK KGIDGSRVEKVLE+V
Sbjct: 836  TPEYKAYQEQVLSNCSKFAETLMKKGYELVSSGTENHLVLVNLKNKGIDGSRVEKVLESV 895

Query: 439  HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            HI +NKNTVPGDVSAMVP GIRMGTPALTSRGFVE+DF KVAEYFD AVT+A+K+K+E  
Sbjct: 896  HIVANKNTVPGDVSAMVPSGIRMGTPALTSRGFVEKDFVKVAEYFDAAVTVAVKIKAETT 955

Query: 259  GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
            GTKLK+F++ M+SS  +QSEIAKLRHEVEE+AKQFPTIGFEKETMKYKN
Sbjct: 956  GTKLKEFLATMQSSPHLQSEIAKLRHEVEEYAKQFPTIGFEKETMKYKN 1004

[14][TOP]
>UniRef100_A7R5Q4 Chromosome undetermined scaffold_1022, whole genome shotgun
           sequence n=1 Tax=Vitis vinifera RepID=A7R5Q4_VITVI
          Length = 173

 Score =  281 bits (719), Expect = 3e-74
 Identities = 138/169 (81%), Positives = 156/169 (92%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EYKAYQEQVLSN +KFA+TLM++GYELVS GT+NHLVLVNLK KGIDGSRVEKVLE+V
Sbjct: 5   TPEYKAYQEQVLSNCSKFAETLMKKGYELVSSGTENHLVLVNLKNKGIDGSRVEKVLESV 64

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HI +NKNTVPGDVSAMVP GIRMGTPALTSRGFVE+DF KVAEYFD AVT+A+K+K+E  
Sbjct: 65  HIVANKNTVPGDVSAMVPSGIRMGTPALTSRGFVEKDFVKVAEYFDAAVTVAVKIKAETT 124

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           GTKLK+F++ M+SS  +QSEIAKLRHEVEE+AKQFPTIGFEKETMKYKN
Sbjct: 125 GTKLKEFLATMQSSPHLQSEIAKLRHEVEEYAKQFPTIGFEKETMKYKN 173

[15][TOP]
>UniRef100_A7NUI3 Serine hydroxymethyltransferase n=1 Tax=Vitis vinifera
           RepID=A7NUI3_VITVI
          Length = 516

 Score =  281 bits (718), Expect = 4e-74
 Identities = 139/169 (82%), Positives = 156/169 (92%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EYKAYQEQVL+N + FAQ+L+E+GYELVSGGTDNHLVLVNLK KGIDGSRVEKVLE+V
Sbjct: 348 TPEYKAYQEQVLTNCSTFAQSLLEKGYELVSGGTDNHLVLVNLKNKGIDGSRVEKVLESV 407

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDF KVAE FD AV +ALK+K+ ++
Sbjct: 408 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAELFDAAVKLALKIKANSK 467

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           GTKLKDFV+ M+S +  QSEIAKLRHEVEE+AKQFPTIGFEKETMKYK+
Sbjct: 468 GTKLKDFVATMQSDAETQSEIAKLRHEVEEYAKQFPTIGFEKETMKYKD 516

[16][TOP]
>UniRef100_P34899 Serine hydroxymethyltransferase, mitochondrial n=1 Tax=Pisum
           sativum RepID=GLYM_PEA
          Length = 518

 Score =  280 bits (717), Expect = 5e-74
 Identities = 138/167 (82%), Positives = 157/167 (94%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EY+AYQEQVLSNS+KFA+ L E+GY+LVSGGT+NHLVLVNLK KGIDGSRVEKVLE V
Sbjct: 350 TPEYRAYQEQVLSNSSKFAKALSEKGYDLVSGGTENHLVLVNLKNKGIDGSRVEKVLELV 409

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDF KVAEYFD AV++ALKVK+E++
Sbjct: 410 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDAAVSLALKVKAESK 469

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKY 119
           GTKLKDFV A+++SS +QSEI+KL+H+VEEFAKQFPTIGFEK TMKY
Sbjct: 470 GTKLKDFVEALQTSSYVQSEISKLKHDVEEFAKQFPTIGFEKATMKY 516

[17][TOP]
>UniRef100_C6ZJY8 Serine hydroxymethyltransferase n=1 Tax=Glycine max
           RepID=C6ZJY8_SOYBN
          Length = 516

 Score =  278 bits (712), Expect = 2e-73
 Identities = 140/169 (82%), Positives = 155/169 (91%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EY+AYQEQVLSNS KFAQ L ER YELVSGGT+NHLVLVNLK KGIDGSRVEKVLEAV
Sbjct: 348 TPEYRAYQEQVLSNSFKFAQALSERSYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAV 407

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDF KVAE+FD AV IA+K+K E++
Sbjct: 408 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEFFDAAVKIAVKIKGESK 467

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           GTKLKDF++ +ESSST QSEIAKLR +VEE+AKQFPTIGF+K TMK+KN
Sbjct: 468 GTKLKDFLATIESSSTFQSEIAKLRLDVEEYAKQFPTIGFDKATMKHKN 516

[18][TOP]
>UniRef100_A9PL10 Serine hydroxymethyltransferase n=1 Tax=Populus tremuloides
           RepID=A9PL10_POPTM
          Length = 520

 Score =  278 bits (711), Expect = 3e-73
 Identities = 139/169 (82%), Positives = 158/169 (93%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EYKAYQEQVLSN AKFAQ+L+E+GYELVSGGT+NHLVLVNLK KGIDGSRVEKVLE+V
Sbjct: 353 TVEYKAYQEQVLSNCAKFAQSLVEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLESV 412

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVA++FD AV +A+K+K+E +
Sbjct: 413 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVADFFDAAVKVAVKIKAETK 472

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           GTKLKDF+ A +S+   QSEI+KLRH+VEE+AKQFPTIGFEKETMKYKN
Sbjct: 473 GTKLKDFL-ATQSAPHFQSEISKLRHDVEEYAKQFPTIGFEKETMKYKN 520

[19][TOP]
>UniRef100_Q3E923 Serine hydroxymethyltransferase n=1 Tax=Arabidopsis thaliana
           RepID=Q3E923_ARATH
          Length = 517

 Score =  277 bits (708), Expect = 6e-73
 Identities = 136/168 (80%), Positives = 155/168 (92%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EYKAYQ+QVL N +KFA+TL+ +GY+LVSGGTDNHLVLVNLK KGIDGSRVEKVLE V
Sbjct: 349 TPEYKAYQDQVLRNCSKFAETLLAKGYDLVSGGTDNHLVLVNLKNKGIDGSRVEKVLELV 408

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGF+EEDFAKVAEYFD AV IALK+K+E+Q
Sbjct: 409 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFIEEDFAKVAEYFDLAVKIALKIKAESQ 468

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYK 116
           GTKLKDFV+ M+S+  +QSE++KLR  VEE+AKQFPTIGFEKETM+YK
Sbjct: 469 GTKLKDFVATMQSNEKLQSEMSKLREMVEEYAKQFPTIGFEKETMRYK 516

[20][TOP]
>UniRef100_A9PL06 Serine hydroxymethyltransferase n=1 Tax=Populus tremuloides
           RepID=A9PL06_POPTM
          Length = 516

 Score =  277 bits (708), Expect = 6e-73
 Identities = 137/169 (81%), Positives = 157/169 (92%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EYKAYQEQVLSN +KFAQ+L+E+GYELVSGGT+NHLVLVNL+ KGIDGSRVEKVLE V
Sbjct: 349 TPEYKAYQEQVLSNCSKFAQSLIEKGYELVSGGTENHLVLVNLRNKGIDGSRVEKVLELV 408

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGF+E DF KVAE+FD AV +ALK+K++AQ
Sbjct: 409 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFIERDFVKVAEFFDAAVKLALKIKADAQ 468

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           GTKLKDFV+AM+S    QSEIA+LRH+VEE+AKQFPT+GFEKETMKYK+
Sbjct: 469 GTKLKDFVAAMKSDG-YQSEIARLRHDVEEYAKQFPTVGFEKETMKYKD 516

[21][TOP]
>UniRef100_Q94C74 Serine hydroxymethyltransferase n=1 Tax=Arabidopsis thaliana
           RepID=Q94C74_ARATH
          Length = 517

 Score =  275 bits (703), Expect = 2e-72
 Identities = 135/168 (80%), Positives = 154/168 (91%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EYKAYQ+QVL N +KFA+TL+ +GY+LVSGGTDNHLVLVNLK KGIDGSRVEKVLE V
Sbjct: 349 TPEYKAYQDQVLRNCSKFAETLLAKGYDLVSGGTDNHLVLVNLKNKGIDGSRVEKVLELV 408

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGI MGTPALTSRGF+EEDFAKVAEYFD AV IALK+K+E+Q
Sbjct: 409 HIAANKNTVPGDVSAMVPGGIHMGTPALTSRGFIEEDFAKVAEYFDLAVKIALKIKAESQ 468

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYK 116
           GTKLKDFV+ M+S+  +QSE++KLR  VEE+AKQFPTIGFEKETM+YK
Sbjct: 469 GTKLKDFVATMQSNEKLQSEMSKLREMVEEYAKQFPTIGFEKETMRYK 516

[22][TOP]
>UniRef100_B9SMX7 Serine hydroxymethyltransferase n=1 Tax=Ricinus communis
           RepID=B9SMX7_RICCO
          Length = 513

 Score =  275 bits (703), Expect = 2e-72
 Identities = 136/169 (80%), Positives = 158/169 (93%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EYKAYQEQVL N +KF+Q+L+E+GYELVSGGT+NHLVLVNL+ KGIDGSRVEKVLE+V
Sbjct: 346 TPEYKAYQEQVLKNCSKFSQSLLEKGYELVSGGTENHLVLVNLRNKGIDGSRVEKVLESV 405

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAE+FD AV +ALK+K++ +
Sbjct: 406 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDAAVKLALKIKADTK 465

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           GTKLKDFV+ M+SS  IQS IA+LRH+VEE+AKQFPT+GFEKETMKYK+
Sbjct: 466 GTKLKDFVATMKSSD-IQSGIAQLRHDVEEYAKQFPTVGFEKETMKYKD 513

[23][TOP]
>UniRef100_A9PJ09 Serine hydroxymethyltransferase n=1 Tax=Populus trichocarpa x
           Populus deltoides RepID=A9PJ09_9ROSI
          Length = 520

 Score =  275 bits (703), Expect = 2e-72
 Identities = 137/169 (81%), Positives = 157/169 (92%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EYKAYQEQVLSN +KFAQ+L+E+GYELVSGGT+NHLVLVNLK KGIDGSRVEKVLE+V
Sbjct: 353 TLEYKAYQEQVLSNCSKFAQSLVEKGYELVSGGTENHLVLVNLKTKGIDGSRVEKVLESV 412

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVA++FD +V +A+K+K+E +
Sbjct: 413 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVADFFDASVKLAVKMKAETK 472

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           GTKLKDF+  M+S+   QSEI+KLRHEVEE+AKQFPTIGF KETMKYKN
Sbjct: 473 GTKLKDFLVTMQSAH-FQSEISKLRHEVEEYAKQFPTIGFNKETMKYKN 520

[24][TOP]
>UniRef100_B6T7Q7 Serine hydroxymethyltransferase n=1 Tax=Zea mays RepID=B6T7Q7_MAIZE
          Length = 513

 Score =  275 bits (702), Expect = 3e-72
 Identities = 140/170 (82%), Positives = 156/170 (91%), Gaps = 1/170 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EY+AYQEQV+SN AKFAQ+L+ +GYELVSGGTDNHLVLVNLK KGIDGSRVEKVLE+V
Sbjct: 345 TPEYRAYQEQVISNCAKFAQSLISKGYELVSGGTDNHLVLVNLKNKGIDGSRVEKVLESV 404

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVA++FD AV +ALK+K+   
Sbjct: 405 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVADFFDAAVNLALKIKAATT 464

Query: 259 -GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
            GTKLKDFV+ ++S S IQ EIAKLRH+VEEFAKQFPTIGFEKETMKYKN
Sbjct: 465 GGTKLKDFVATLQSDS-IQVEIAKLRHDVEEFAKQFPTIGFEKETMKYKN 513

[25][TOP]
>UniRef100_B9HK13 Serine hydroxymethyltransferase (Fragment) n=2 Tax=Populus
           RepID=B9HK13_POPTR
          Length = 518

 Score =  275 bits (702), Expect = 3e-72
 Identities = 137/169 (81%), Positives = 157/169 (92%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EYKAYQEQVLSN +KFAQ+L+E+GYELVSGGT+NHLVLVNLK KGIDGSRVEKVLE+V
Sbjct: 351 TLEYKAYQEQVLSNCSKFAQSLVEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLESV 410

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVA++FD +V +A+K+K+E +
Sbjct: 411 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVADFFDASVKLAVKMKAETK 470

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           GTKLKDF+  M+S+   QSEI+KLRHEVEE+AKQFPTIGF KETMKYKN
Sbjct: 471 GTKLKDFLVTMQSAH-FQSEISKLRHEVEEYAKQFPTIGFNKETMKYKN 518

[26][TOP]
>UniRef100_A9PIN8 Serine hydroxymethyltransferase n=1 Tax=Populus trichocarpa x
           Populus deltoides RepID=A9PIN8_9ROSI
          Length = 520

 Score =  275 bits (702), Expect = 3e-72
 Identities = 138/169 (81%), Positives = 157/169 (92%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EYKAYQEQVLSN AKFAQ+L+E+GYELVSGGT+NHLVLVNLK KGIDGSRVEKVLE+V
Sbjct: 353 TVEYKAYQEQVLSNCAKFAQSLVEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLESV 412

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVA++FD AV +A+K+K+E +
Sbjct: 413 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVADFFDAAVKLAVKIKAETK 472

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           GTKLKDF+ A +S+   QSEI+KLR +VEE+AKQFPTIGFEKETMKYKN
Sbjct: 473 GTKLKDFL-ATQSAPHFQSEISKLRRDVEEYAKQFPTIGFEKETMKYKN 520

[27][TOP]
>UniRef100_B9GN69 Serine hydroxymethyltransferase n=1 Tax=Populus trichocarpa
           RepID=B9GN69_POPTR
          Length = 516

 Score =  274 bits (701), Expect = 4e-72
 Identities = 136/169 (80%), Positives = 156/169 (92%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EYKAYQEQVLSN +KFAQ+L+E+GYELVSGGT+NHLVLVNL+ KGIDGSRVEKVLE V
Sbjct: 349 TPEYKAYQEQVLSNCSKFAQSLIEKGYELVSGGTENHLVLVNLRNKGIDGSRVEKVLELV 408

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGF+E DF KVAE+FD AV +ALK+K++AQ
Sbjct: 409 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFIERDFVKVAEFFDAAVKLALKIKADAQ 468

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           G KLKDFV+AM+S    QSEIA+LRH+VEE+AKQFPT+GFEKETMKYK+
Sbjct: 469 GMKLKDFVAAMKSDGH-QSEIARLRHDVEEYAKQFPTVGFEKETMKYKD 516

[28][TOP]
>UniRef100_B9HV02 Serine hydroxymethyltransferase n=1 Tax=Populus trichocarpa
           RepID=B9HV02_POPTR
          Length = 520

 Score =  273 bits (698), Expect = 8e-72
 Identities = 137/169 (81%), Positives = 157/169 (92%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EYKAYQEQVLSN AKFAQ+L+E+GYELVSGGT+NHLVLVNLK KGIDGSRVEKVLE+V
Sbjct: 353 TVEYKAYQEQVLSNCAKFAQSLVEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLESV 412

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVA++FD AV +A+++K+E +
Sbjct: 413 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVADFFDAAVKLAVEIKAETK 472

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           GTKLKDF+ A +S+   QSEI+KLR +VEE+AKQFPTIGFEKETMKYKN
Sbjct: 473 GTKLKDFL-ATQSAPHFQSEISKLRRDVEEYAKQFPTIGFEKETMKYKN 520

[29][TOP]
>UniRef100_B9SMK7 Serine hydroxymethyltransferase n=1 Tax=Ricinus communis
           RepID=B9SMK7_RICCO
          Length = 515

 Score =  273 bits (697), Expect = 1e-71
 Identities = 137/169 (81%), Positives = 152/169 (89%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           TSEYKAYQEQVLSN AKFAQTL ++GYELVSGGT+NHLVLVNLK KGIDGSRVEKVLEAV
Sbjct: 350 TSEYKAYQEQVLSNCAKFAQTLAQKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAV 409

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGF+EEDFAKVAE+FD AV +A+K+K E +
Sbjct: 410 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFIEEDFAKVAEFFDAAVKLAVKIKGETK 469

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           GTKLKDF++ +      QS+I KLRH VEE+AKQFPTIGFEK TMKYKN
Sbjct: 470 GTKLKDFLATIPQ---FQSDITKLRHAVEEYAKQFPTIGFEKGTMKYKN 515

[30][TOP]
>UniRef100_Q8GRI1 Serine hydroxymethyltransferase n=1 Tax=Arabidopsis thaliana
           RepID=Q8GRI1_ARATH
          Length = 533

 Score =  268 bits (684), Expect = 4e-70
 Identities = 137/184 (74%), Positives = 155/184 (84%), Gaps = 16/184 (8%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFA----------------QTLMERGYELVSGGTDNHLVLVNLK 488
           T EYKAYQ+QVL N +KFA                QTL+ +GY+LVSGGTDNHLVLVNLK
Sbjct: 349 TPEYKAYQDQVLRNCSKFAELDIRPTVIISYGLSMQTLLAKGYDLVSGGTDNHLVLVNLK 408

Query: 487 PKGIDGSRVEKVLEAVHIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEY 308
            KGIDGSRVEKVLE VHIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGF+EEDFAKVAEY
Sbjct: 409 NKGIDGSRVEKVLELVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFIEEDFAKVAEY 468

Query: 307 FDKAVTIALKVKSEAQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKET 128
           FD AV IALK+K+E+QGTKLKDFV+ M+S+  +QSE++KLR  VEE+AKQFPTIGFEKET
Sbjct: 469 FDLAVKIALKIKAESQGTKLKDFVATMQSNEKLQSEMSKLREMVEEYAKQFPTIGFEKET 528

Query: 127 MKYK 116
           M+YK
Sbjct: 529 MRYK 532

[31][TOP]
>UniRef100_Q45FE6 Serine hydroxymethyltransferase n=1 Tax=Medicago truncatula
           RepID=Q45FE6_MEDTR
          Length = 507

 Score =  267 bits (683), Expect = 5e-70
 Identities = 132/167 (79%), Positives = 152/167 (91%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ+QVLSNS+ FAQ+L+E+GY+LVSGGT+NHLVLVNL+ KGIDGSRVEKVLE+V
Sbjct: 339 TPEFKNYQKQVLSNSSTFAQSLLEKGYDLVSGGTENHLVLVNLRNKGIDGSRVEKVLESV 398

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGFVE+DF KVAEYFD AV IAL++K  ++
Sbjct: 399 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEDDFKKVAEYFDAAVKIALQIKENSK 458

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKY 119
           GTKLKDFV AMES S +QS+IA LRH+VE +AKQFPTIGFE ETMKY
Sbjct: 459 GTKLKDFVEAMESDSQVQSQIADLRHDVEGYAKQFPTIGFEIETMKY 505

[32][TOP]
>UniRef100_B2BGS6 Glycine/serine hydroxymethyltransferase reductase (Fragment) n=1
           Tax=Olea europaea RepID=B2BGS6_OLEEU
          Length = 197

 Score =  265 bits (677), Expect = 2e-69
 Identities = 133/166 (80%), Positives = 152/166 (91%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EYKAYQEQV+SN +KFAQTL+++ Y+LVSGGT+NHLVLVNLK KGIDGSRVEKVLE+V
Sbjct: 35  TPEYKAYQEQVMSNCSKFAQTLVKKSYDLVSGGTENHLVLVNLKNKGIDGSRVEKVLESV 94

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDF KVAE+FD +V +ALK+K+  Q
Sbjct: 95  HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEFFDASVKLALKIKANTQ 154

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMK 122
           GTKLKDFV+AM+SS+   SEI KLR +VEE+AKQFPTIGFEKETMK
Sbjct: 155 GTKLKDFVTAMQSST---SEIEKLRQDVEEYAKQFPTIGFEKETMK 197

[33][TOP]
>UniRef100_B8LLV3 Serine hydroxymethyltransferase n=1 Tax=Picea sitchensis
           RepID=B8LLV3_PICSI
          Length = 428

 Score =  264 bits (674), Expect = 5e-69
 Identities = 132/170 (77%), Positives = 151/170 (88%), Gaps = 1/170 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           TSEYKAYQEQVLSN A FA+ L ERGYELVSGGTDNHLVLVNLK KGIDGSRVE+VLE V
Sbjct: 259 TSEYKAYQEQVLSNCAHFAKCLSERGYELVSGGTDNHLVLVNLKNKGIDGSRVERVLELV 318

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGD+SAMVPGGIRMGTPALTSRGF+E+DFAKVAE+FD A  +A+++KSE +
Sbjct: 319 HIAANKNTVPGDISAMVPGGIRMGTPALTSRGFIEDDFAKVAEFFDIAAQLAIRIKSETK 378

Query: 259 -GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
            G+KLKDF + MESS   Q+EIA LRH VEE+AKQFPTIGFEK ++KYK+
Sbjct: 379 GGSKLKDFKATMESSPHFQAEIASLRHNVEEYAKQFPTIGFEKTSLKYKD 428

[34][TOP]
>UniRef100_A7R7N7 Serine hydroxymethyltransferase (Fragment) n=1 Tax=Vitis vinifera
           RepID=A7R7N7_VITVI
          Length = 305

 Score =  261 bits (668), Expect = 3e-68
 Identities = 129/155 (83%), Positives = 146/155 (94%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           TSEYKAYQEQVLSN +KFA+TL+++GYELVSGGT+NHLVLVNLK KGIDGSRVEKVLE+V
Sbjct: 151 TSEYKAYQEQVLSNCSKFAETLIKKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLESV 210

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDF KVAEYFD AVT+A+K+K+E  
Sbjct: 211 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDAAVTVAVKIKAETT 270

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQF 155
           GTKLKDF++ M+SS  +QSEIAKLRHEVEE+AKQF
Sbjct: 271 GTKLKDFLATMQSSPHLQSEIAKLRHEVEEYAKQF 305

[35][TOP]
>UniRef100_A9RQ31 Serine hydroxymethyltransferase n=1 Tax=Physcomitrella patens
           subsp. patens RepID=A9RQ31_PHYPA
          Length = 479

 Score =  261 bits (667), Expect = 3e-68
 Identities = 130/174 (74%), Positives = 148/174 (85%), Gaps = 5/174 (2%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+KAYQEQVL NSA FA+ LM RGYELVSGGT+NHLVLVNLKPKG+DGSRVE+V+E  
Sbjct: 306 TPEFKAYQEQVLRNSAHFAKALMGRGYELVSGGTENHLVLVNLKPKGVDGSRVERVMELA 365

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-- 266
           HIA+NKNTVPGDVSA+VPGGIRMGTPALTSRGF EEDF KVAEYFD+AV IA+KVK    
Sbjct: 366 HIAANKNTVPGDVSALVPGGIRMGTPALTSRGFTEEDFEKVAEYFDRAVEIAVKVKKSTA 425

Query: 265 ---AQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
                GTKLKDF + +++   +Q+EI KL+HEVEEFAKQFPTIGFEK +MKYKN
Sbjct: 426 LFPVAGTKLKDFRNVVDTDPEVQAEIGKLKHEVEEFAKQFPTIGFEKSSMKYKN 479

[36][TOP]
>UniRef100_A9SHC0 Serine hydroxymethyltransferase n=1 Tax=Physcomitrella patens
           subsp. patens RepID=A9SHC0_PHYPA
          Length = 473

 Score =  261 bits (666), Expect = 4e-68
 Identities = 129/169 (76%), Positives = 152/169 (89%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+KAYQEQVLSNSA+FA+ LM +GYELVSGGT+NHLVLVNLKPKG+DGSRVE+V+E  
Sbjct: 306 TPEFKAYQEQVLSNSARFAKALMSQGYELVSGGTENHLVLVNLKPKGVDGSRVERVMELA 365

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSA+VPGGIRMGTPALTSRGF+EEDF KVAE+FD+AV IA+KVK ++ 
Sbjct: 366 HIAANKNTVPGDVSALVPGGIRMGTPALTSRGFIEEDFEKVAEFFDRAVGIAVKVK-KST 424

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           G KLKDF +A+++   IQ+EI KLR EVEEFAKQFPTIGFEK +MKY+N
Sbjct: 425 GAKLKDFRAAVDTDPEIQAEIGKLRTEVEEFAKQFPTIGFEKSSMKYQN 473

[37][TOP]
>UniRef100_A9NUX0 Serine hydroxymethyltransferase n=1 Tax=Picea sitchensis
           RepID=A9NUX0_PICSI
          Length = 519

 Score =  259 bits (662), Expect = 1e-67
 Identities = 129/169 (76%), Positives = 149/169 (88%), Gaps = 1/169 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K+YQEQVLSN A FA  L++RGYELVSGGTDNHLVLVNLK KGIDGSRVE+VLE  
Sbjct: 350 TPEFKSYQEQVLSNCAHFAHCLIKRGYELVSGGTDNHLVLVNLKNKGIDGSRVERVLELA 409

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSAM+PGGIRMGTPALTSRGF+E+DFAKVAE+FD AV +++K+KSE +
Sbjct: 410 HIAANKNTVPGDVSAMIPGGIRMGTPALTSRGFLEDDFAKVAEFFDLAVQLSIKIKSETK 469

Query: 259 -GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYK 116
            G+KLKDF + +ESS  IQ EI  LRHEVEE+AKQFPTIGFEK +MKYK
Sbjct: 470 GGSKLKDFKATIESSPAIQDEIRNLRHEVEEYAKQFPTIGFEKSSMKYK 518

[38][TOP]
>UniRef100_A7R6Z2 Chromosome undetermined scaffold_1500, whole genome shotgun
           sequence (Fragment) n=1 Tax=Vitis vinifera
           RepID=A7R6Z2_VITVI
          Length = 1257

 Score =  224 bits (570), Expect = 6e-57
 Identities = 110/134 (82%), Positives = 124/134 (92%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EYKAYQEQVLSN +KFA+TLM++GYELVSGGT+NHLVLVNLK KGIDGSRVEKVLE+V
Sbjct: 38  TPEYKAYQEQVLSNCSKFAETLMKKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLESV 97

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HI +NKNTVPGDVSAMVP GIRMGTPALTSRGFVEEDF KVAEYFD AVT+A+K+K+E  
Sbjct: 98  HIVANKNTVPGDVSAMVPSGIRMGTPALTSRGFVEEDFVKVAEYFDVAVTVAVKIKAETT 157

Query: 259 GTKLKDFVSAMESS 218
           GTKLKDF++ M+SS
Sbjct: 158 GTKLKDFLAIMQSS 171

[39][TOP]
>UniRef100_Q8W4V3 Serine hydroxymethyltransferase n=1 Tax=Chlamydomonas reinhardtii
           RepID=Q8W4V3_CHLRE
          Length = 520

 Score =  212 bits (539), Expect = 2e-53
 Identities = 107/169 (63%), Positives = 136/169 (80%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K+YQ+QVLSNS   A  L +RG++LVSGGTDNH+VLV+L+PKG+DGSRVE+VLE  
Sbjct: 356 TPEFKSYQQQVLSNSQALAGALAKRGFKLVSGGTDNHIVLVDLRPKGVDGSRVERVLELA 415

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA+NKNTVPGDVSA+VPGG+RMG+PALTSRGFVE+DF +VAE+ D+AV IA+ +K +  
Sbjct: 416 HIAANKNTVPGDVSALVPGGLRMGSPALTSRGFVEKDFEQVAEFVDRAVNIAVDLKKKY- 474

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
             KLK+F  AM   ST   +I  L+ +VE FA +FPTIGF+K  M+YKN
Sbjct: 475 -PKLKEFREAMAKEST--PDINALKKDVETFAMRFPTIGFDKAAMRYKN 520

[40][TOP]
>UniRef100_A4SBB9 Serine hydroxymethyltransferase n=1 Tax=Ostreococcus lucimarinus
           CCE9901 RepID=A4SBB9_OSTLU
          Length = 525

 Score =  208 bits (529), Expect = 3e-52
 Identities = 104/165 (63%), Positives = 129/165 (78%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+KAYQ QV+SN    A  L++ G +LVSGGTDNHL L++L+P G+DGSRVE+VLE  HI
Sbjct: 359 EFKAYQRQVMSNMQAMANRLVQHGIKLVSGGTDNHLALLDLRPMGVDGSRVERVLELAHI 418

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           A NKNTVPGDVSAMVPGG+R+GTPALTSRGF E+DF +VAE+  + + IA  VKS+++GT
Sbjct: 419 ACNKNTVPGDVSAMVPGGLRIGTPALTSRGFTEKDFEQVAEFIVRGIKIAQDVKSKSEGT 478

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKY 119
           KLKDF +A+ES      E+ +L  +VEEFA QFPTIGFEK   KY
Sbjct: 479 KLKDFRAALESKE--WPELTQLTKDVEEFATQFPTIGFEKAEGKY 521

[41][TOP]
>UniRef100_A5BJY0 Putative uncharacterized protein n=1 Tax=Vitis vinifera
           RepID=A5BJY0_VITVI
          Length = 523

 Score =  207 bits (526), Expect = 7e-52
 Identities = 108/155 (69%), Positives = 124/155 (80%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EYKAYQEQVLSN +KFA+TLM++GYELVSGGT+NHLVLVNLK KGIDGSRVEKVLE+V
Sbjct: 350 TPEYKAYQEQVLSNCSKFAETLMKKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLESV 409

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HI +NKNTVPGDVSAMVP GIRMG            DF KVAEYFD AVT+A+K+K+E  
Sbjct: 410 HIVANKNTVPGDVSAMVPSGIRMG-----------RDFVKVAEYFDXAVTVAVKIKAETT 458

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQF 155
           GTKLK F++ M+SS  +Q EIAKLRHE  E  + F
Sbjct: 459 GTKLKXFLAXMQSSPHLQXEIAKLRHEGVETLQIF 493

[42][TOP]
>UniRef100_B5YLQ7 Glycine or serine hydroxymethyltransferase, serine methylase n=1
           Tax=Thalassiosira pseudonana CCMP1335 RepID=B5YLQ7_THAPS
          Length = 531

 Score =  205 bits (522), Expect = 2e-51
 Identities = 104/169 (61%), Positives = 127/169 (75%), Gaps = 1/169 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKP-KGIDGSRVEKVLEA 443
           T E+  YQ+QVL N A+    L   GYE+VSGGTDNHLVLVN+K  KGIDG+RVE+VLE 
Sbjct: 354 TPEFVEYQKQVLKNCARLNSELQSLGYEIVSGGTDNHLVLVNVKSSKGIDGARVERVLEL 413

Query: 442 VHIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEA 263
             IASNKNTVPGD SA+ PGGIRMGTPALTSRGF+EEDFAKVA YFD+AV+IA K+K+  
Sbjct: 414 ACIASNKNTVPGDTSALNPGGIRMGTPALTSRGFMEEDFAKVAHYFDRAVSIANKLKNTE 473

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYK 116
           +G K+K F        ++  E+ +LR EV EFA  FPT+GFE+  M++K
Sbjct: 474 EGKKMKGFREMCAVGPSVDPELVQLRKEVSEFASSFPTVGFEESEMEFK 522

[43][TOP]
>UniRef100_B7FQ66 Serine hydroxymethyltransferase n=1 Tax=Phaeodactylum tricornutum
           CCAP 1055/1 RepID=B7FQ66_PHATR
          Length = 501

 Score =  194 bits (494), Expect = 4e-48
 Identities = 94/169 (55%), Positives = 129/169 (76%), Gaps = 1/169 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKG-IDGSRVEKVLEA 443
           T+++  YQ+QVL NS++ A+ L + GY LVSGGTDNHLVL+++K    IDG+RVE++LE 
Sbjct: 324 TADFVVYQKQVLKNSSRLAEELNKLGYTLVSGGTDNHLVLIDVKSSAKIDGARVERILEL 383

Query: 442 VHIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEA 263
             IA+NKNTVPGD SA++PGGIRMGTPALTSRGF E+DF KVA +FD+AV IA+K+K+  
Sbjct: 384 ACIATNKNTVPGDTSALMPGGIRMGTPALTSRGFKEDDFTKVAHFFDRAVKIAVKLKNTD 443

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYK 116
           QG KLK F        ++ +++ +LRH+V EFA  FPT+GF ++ M ++
Sbjct: 444 QGAKLKGFREMCAVGPSVDADLVQLRHDVSEFACLFPTVGFNEDEMTFE 492

[44][TOP]
>UniRef100_Q00VT2 Serine hydroxymethyltransferase n=1 Tax=Ostreococcus tauri
           RepID=Q00VT2_OSTTA
          Length = 543

 Score =  187 bits (476), Expect = 5e-46
 Identities = 97/165 (58%), Positives = 119/165 (72%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+KAYQ QVLSN    A+ L E G +LVSGGT NHL L++L+P G+DGSRVE+VLE  HI
Sbjct: 377 EFKAYQLQVLSNMQACAKRLQEHGVKLVSGGTVNHLALLDLRPMGVDGSRVERVLELAHI 436

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           A NKNTVPGDVSAMVPGG+R+GTPALTSRGF+E+DF  VA+   + + I   +   A+GT
Sbjct: 437 ACNKNTVPGDVSAMVPGGLRIGTPALTSRGFLEKDFETVADLIVRGIHITKTINDSAKGT 496

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKY 119
           KLKDF  A+ S      E+ +L  +VE  A +FPTIGFEK   KY
Sbjct: 497 KLKDFREALASKE--WPELTQLTKDVENLATRFPTIGFEKAEGKY 539

[45][TOP]
>UniRef100_C1MWT5 Serine hydroxymethyltransferase n=1 Tax=Micromonas pusilla CCMP1545
           RepID=C1MWT5_9CHLO
          Length = 517

 Score =  184 bits (468), Expect = 4e-45
 Identities = 97/166 (58%), Positives = 119/166 (71%), Gaps = 1/166 (0%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           ++K YQ QV+ N    +  L + G ELVSGGTDNHLVL +L+P G+DGSRVE+VLE  HI
Sbjct: 349 DFKKYQNQVMKNMVAMSDRLKKHGVELVSGGTDNHLVLADLRPLGVDGSRVERVLELAHI 408

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           A NKNTVPGD SAMVPGG+R+GTPALT+RGFVE DF +VA+   K + I  K+K E  G 
Sbjct: 409 ACNKNTVPGDKSAMVPGGLRLGTPALTTRGFVEADFERVADMVWKGIEITKKLK-EVHGP 467

Query: 253 KLKDF-VSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKY 119
           KLKDF V+  ++      EI  L+ EVE FA QFPTIGF+K+  KY
Sbjct: 468 KLKDFRVALADAPPGKFPEIDALKSEVEAFAAQFPTIGFDKKDGKY 513

[46][TOP]
>UniRef100_UPI000052319C PREDICTED: similar to Shmt2 protein n=1 Tax=Ciona intestinalis
           RepID=UPI000052319C
          Length = 489

 Score =  182 bits (461), Expect = 3e-44
 Identities = 91/158 (57%), Positives = 116/158 (73%)
 Frame = -3

Query: 610 YKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIA 431
           +K YQ Q L N+A  A  L  RGY LVSGGTDNHLVLV+L+PKGIDG+R EKVLE   + 
Sbjct: 332 FKEYQIQTLKNAATMASELTARGYNLVSGGTDNHLVLVDLRPKGIDGARTEKVLELASVT 391

Query: 430 SNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTK 251
            NKN+VPGD SA++PGG+R+G PALTSR FVEEDF KV ++ DK V IA++ K + +  K
Sbjct: 392 VNKNSVPGDKSALMPGGLRLGAPALTSRDFVEEDFVKVVDFLDKGVEIAIEAKKKTK--K 449

Query: 250 LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFE 137
           L DF S +E++     +I+ LR+EVE+FA+ FP  GFE
Sbjct: 450 LADFKSFIETNPETVEKISNLRNEVEKFARSFPMPGFE 487

[47][TOP]
>UniRef100_C1EFW6 Serine hydroxymethyltransferase n=1 Tax=Micromonas sp. RCC299
           RepID=C1EFW6_9CHLO
          Length = 491

 Score =  181 bits (460), Expect = 3e-44
 Identities = 96/166 (57%), Positives = 119/166 (71%), Gaps = 1/166 (0%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+KAYQ QV+ N    ++ L   G ELVSGGTDNHLVL +L+P G+DGSRVE+VLE  HI
Sbjct: 323 EFKAYQTQVMRNMHAMSERLKSHGIELVSGGTDNHLVLADLRPLGVDGSRVERVLELAHI 382

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           A NKNTVPGD SAMVPGG+R+GTPALT+RGFVE DF KVA++  + + IA  +K++  G 
Sbjct: 383 ACNKNTVPGDKSAMVPGGLRLGTPALTTRGFVEADFEKVADFVVRGIHIAKDLKTKL-GP 441

Query: 253 KLKDFVSAMESSSTIQ-SEIAKLRHEVEEFAKQFPTIGFEKETMKY 119
           KLKDF   +  +   +  EI  L+ EVE FA  FPTIGF+K   KY
Sbjct: 442 KLKDFRDGLSHAPEGKFPEIDALKAEVEAFAATFPTIGFDKAEGKY 487

[48][TOP]
>UniRef100_Q00SC2 Serine hydroxymethyltransferase n=1 Tax=Ostreococcus tauri
           RepID=Q00SC2_OSTTA
          Length = 542

 Score =  178 bits (452), Expect = 3e-43
 Identities = 88/155 (56%), Positives = 115/155 (74%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  +  YQEQV+ N A  A+ LME GY LVSGGTDNHLVL +L+PKG+DG+RVEK+L+  
Sbjct: 336 TPGFVKYQEQVIKNCAAMAKRLMELGYTLVSGGTDNHLVLCDLRPKGVDGARVEKILDLC 395

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HI  NKN+VPGD SA+VPGGIR+G+PA+T+RG  E DF +VA+  DK V IA+ +K + +
Sbjct: 396 HITLNKNSVPGDTSALVPGGIRIGSPAMTTRGMTEADFIRVADLIDKGVNIAIDIKGKTE 455

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQF 155
           G KLKDF + +E++      IA+LR EVE FA +F
Sbjct: 456 GGKLKDFKAYLEANDV--PAIAELRAEVEAFADEF 488

[49][TOP]
>UniRef100_Q3SZ20 Serine hydroxymethyltransferase, mitochondrial n=1 Tax=Bos taurus
           RepID=GLYM_BOVIN
          Length = 504

 Score =  178 bits (451), Expect = 4e-43
 Identities = 88/161 (54%), Positives = 115/161 (71%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  Q+L N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 344 TPMFREYSLQILKNAQAMANALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 403

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSRGF+E+DF KV  + D+ V I L+VKS+  
Sbjct: 404 SITANKNTCPGDRSAITPGGLRLGAPALTSRGFLEDDFRKVVGFIDEGVNIGLEVKSKT- 462

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFE 137
            TKL+DF S +        ++A LR  VE+FA+ FP  GF+
Sbjct: 463 -TKLQDFKSFLLKDPETSHQLADLRQRVEQFARAFPMPGFD 502

[50][TOP]
>UniRef100_UPI00017F00A6 PREDICTED: similar to Serine hydroxymethyltransferase 2
           (mitochondrial) n=1 Tax=Sus scrofa RepID=UPI00017F00A6
          Length = 505

 Score =  177 bits (450), Expect = 5e-43
 Identities = 91/162 (56%), Positives = 116/162 (71%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+RVE+VLE V
Sbjct: 345 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARVERVLELV 404

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+GTPALTSR F E+DF KV  + D+ V+I L+VKS+  
Sbjct: 405 SITANKNTCPGDRSAITPGGLRLGTPALTSRQFREDDFRKVVAFIDEGVSIGLEVKSKT- 463

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
            TKL+DF S +         +A LR  VE+FA+ FP  GFE+
Sbjct: 464 -TKLQDFKSFLLKDPETCRRLADLRQRVEQFARAFPMPGFEE 504

[51][TOP]
>UniRef100_UPI0000E230C0 PREDICTED: serine hydroxymethyltransferase 2 (mitochondrial) n=1
           Tax=Pan troglodytes RepID=UPI0000E230C0
          Length = 506

 Score =  174 bits (442), Expect = 4e-42
 Identities = 87/162 (53%), Positives = 114/162 (70%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 344 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 403

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VKS+  
Sbjct: 404 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT- 462

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 463 -AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFDE 503

[52][TOP]
>UniRef100_UPI0001AE6AEB UPI0001AE6AEB related cluster n=1 Tax=Homo sapiens
           RepID=UPI0001AE6AEB
          Length = 513

 Score =  174 bits (442), Expect = 4e-42
 Identities = 87/162 (53%), Positives = 114/162 (70%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 353 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 412

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VKS+  
Sbjct: 413 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT- 471

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 472 -AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFDE 512

[53][TOP]
>UniRef100_UPI0001AE6AEA UPI0001AE6AEA related cluster n=1 Tax=Homo sapiens
           RepID=UPI0001AE6AEA
          Length = 442

 Score =  174 bits (442), Expect = 4e-42
 Identities = 87/162 (53%), Positives = 114/162 (70%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 282 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 341

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VKS+  
Sbjct: 342 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT- 400

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 401 -AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFDE 441

[54][TOP]
>UniRef100_Q8N1A5 Serine hydroxymethyltransferase n=1 Tax=Homo sapiens
           RepID=Q8N1A5_HUMAN
          Length = 494

 Score =  174 bits (442), Expect = 4e-42
 Identities = 87/162 (53%), Positives = 114/162 (70%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 334 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 393

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VKS+  
Sbjct: 394 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT- 452

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 453 -AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFDE 493

[55][TOP]
>UniRef100_Q5HYG8 Serine hydroxymethyltransferase n=1 Tax=Homo sapiens
           RepID=Q5HYG8_HUMAN
          Length = 483

 Score =  174 bits (442), Expect = 4e-42
 Identities = 87/162 (53%), Positives = 114/162 (70%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 323 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 382

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VKS+  
Sbjct: 383 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT- 441

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 442 -AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFDE 482

[56][TOP]
>UniRef100_Q5BJF5 Serine hydroxymethyltransferase (Fragment) n=1 Tax=Homo sapiens
           RepID=Q5BJF5_HUMAN
          Length = 480

 Score =  174 bits (442), Expect = 4e-42
 Identities = 87/162 (53%), Positives = 114/162 (70%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 320 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 379

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VKS+  
Sbjct: 380 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT- 438

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 439 -AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFDE 479

[57][TOP]
>UniRef100_Q53ET4 Serine hydroxymethyltransferase (Fragment) n=1 Tax=Homo sapiens
           RepID=Q53ET4_HUMAN
          Length = 504

 Score =  174 bits (442), Expect = 4e-42
 Identities = 87/162 (53%), Positives = 114/162 (70%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 344 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 403

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VKS+  
Sbjct: 404 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFHEDDFRRVVDFIDEGVNIGLEVKSKT- 462

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 463 -AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFDE 503

[58][TOP]
>UniRef100_B4E1G2 Serine hydroxymethyltransferase n=1 Tax=Homo sapiens
           RepID=B4E1G2_HUMAN
          Length = 442

 Score =  174 bits (442), Expect = 4e-42
 Identities = 87/162 (53%), Positives = 114/162 (70%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 282 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 341

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VKS+  
Sbjct: 342 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT- 400

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 401 -AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFDE 441

[59][TOP]
>UniRef100_B4DWA7 Serine hydroxymethyltransferase n=1 Tax=Homo sapiens
           RepID=B4DWA7_HUMAN
          Length = 513

 Score =  174 bits (442), Expect = 4e-42
 Identities = 87/162 (53%), Positives = 114/162 (70%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 353 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 412

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VKS+  
Sbjct: 413 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT- 471

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 472 -AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFDE 512

[60][TOP]
>UniRef100_B4DP88 Serine hydroxymethyltransferase n=1 Tax=Homo sapiens
           RepID=B4DP88_HUMAN
          Length = 435

 Score =  174 bits (442), Expect = 4e-42
 Identities = 87/162 (53%), Positives = 114/162 (70%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 275 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 334

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VKS+  
Sbjct: 335 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT- 393

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 394 -AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFDE 434

[61][TOP]
>UniRef100_B4DLV4 cDNA FLJ58585, highly similar to Serine hydroxymethyltransferase,
           mitochondrial (EC 2.1.2.1) n=1 Tax=Homo sapiens
           RepID=B4DLV4_HUMAN
          Length = 408

 Score =  174 bits (442), Expect = 4e-42
 Identities = 87/162 (53%), Positives = 114/162 (70%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 248 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 307

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VKS+  
Sbjct: 308 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT- 366

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 367 -AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFDE 407

[62][TOP]
>UniRef100_B4DJ63 Serine hydroxymethyltransferase n=1 Tax=Homo sapiens
           RepID=B4DJ63_HUMAN
          Length = 378

 Score =  174 bits (442), Expect = 4e-42
 Identities = 87/162 (53%), Positives = 114/162 (70%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 218 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 277

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VKS+  
Sbjct: 278 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT- 336

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 337 -AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFDE 377

[63][TOP]
>UniRef100_P34897 Serine hydroxymethyltransferase, mitochondrial n=2 Tax=Homo sapiens
           RepID=GLYM_HUMAN
          Length = 504

 Score =  174 bits (442), Expect = 4e-42
 Identities = 87/162 (53%), Positives = 114/162 (70%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 344 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 403

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VKS+  
Sbjct: 404 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT- 462

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 463 -AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFDE 503

[64][TOP]
>UniRef100_C4R8C2 Serine hydroxymethyltransferase n=1 Tax=Pichia pastoris GS115
           RepID=C4R8C2_PICPG
          Length = 497

 Score =  174 bits (440), Expect = 7e-42
 Identities = 84/159 (52%), Positives = 120/159 (75%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+ +YQ+ V+ NS  FA++ ++RG++LVSGGTD HL+LV+L+ K IDG+RVE VLE +
Sbjct: 337 TPEFVSYQQAVVDNSKSFAESFIKRGFQLVSGGTDTHLILVDLRNKKIDGARVENVLEKI 396

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           +IA+NKNTVPGDVSA+ P G+R+GTPA+T+RGF   DF +VA YF+KAV IA+ +KS  +
Sbjct: 397 NIAANKNTVPGDVSALFPSGLRVGTPAMTTRGFTAADFDRVAGYFEKAVAIAIDLKSGEK 456

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
           G+  K+ +++ +S +   +EI KL  EV E+A  FP  G
Sbjct: 457 GSLAKEKLASFKSLAEDSAEIKKLAQEVSEWASTFPVPG 495

[65][TOP]
>UniRef100_UPI0000D9CD41 PREDICTED: similar to serine hydroxymethyltransferase 2
           (mitochondrial) isoform 8 n=1 Tax=Macaca mulatta
           RepID=UPI0000D9CD41
          Length = 465

 Score =  172 bits (437), Expect = 2e-41
 Identities = 86/162 (53%), Positives = 114/162 (70%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 305 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 364

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VK++  
Sbjct: 365 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKTKT- 423

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 424 -AKLQDFKSFLLKDSETSQRLADLRQRVEQFARGFPMPGFDE 464

[66][TOP]
>UniRef100_UPI0000D9CD40 PREDICTED: similar to serine hydroxymethyltransferase 2
           (mitochondrial) isoform 1 n=1 Tax=Macaca mulatta
           RepID=UPI0000D9CD40
          Length = 495

 Score =  172 bits (437), Expect = 2e-41
 Identities = 86/162 (53%), Positives = 114/162 (70%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 335 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 394

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VK++  
Sbjct: 395 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKTKT- 453

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 454 -AKLQDFKSFLLKDSETSQRLADLRQRVEQFARGFPMPGFDE 494

[67][TOP]
>UniRef100_UPI0000D9CD3F PREDICTED: similar to serine hydroxymethyltransferase 2
           (mitochondrial) isoform 5 n=1 Tax=Macaca mulatta
           RepID=UPI0000D9CD3F
          Length = 499

 Score =  172 bits (437), Expect = 2e-41
 Identities = 86/162 (53%), Positives = 114/162 (70%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 339 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 398

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VK++  
Sbjct: 399 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKTKT- 457

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 458 -AKLQDFKSFLLKDSETSQRLADLRQRVEQFARGFPMPGFDE 498

[68][TOP]
>UniRef100_UPI0000D9CD3E PREDICTED: similar to serine hydroxymethyltransferase 2
           (mitochondrial) isoform 10 n=2 Tax=Macaca mulatta
           RepID=UPI0000D9CD3E
          Length = 509

 Score =  172 bits (437), Expect = 2e-41
 Identities = 86/162 (53%), Positives = 114/162 (70%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 349 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 408

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VK++  
Sbjct: 409 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKTKT- 467

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 468 -AKLQDFKSFLLKDSETSQRLADLRQRVEQFARGFPMPGFDE 508

[69][TOP]
>UniRef100_UPI0000D9CD3D PREDICTED: similar to serine hydroxymethyltransferase 2
           (mitochondrial) isoform 9 n=1 Tax=Macaca mulatta
           RepID=UPI0000D9CD3D
          Length = 496

 Score =  172 bits (437), Expect = 2e-41
 Identities = 86/162 (53%), Positives = 114/162 (70%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 336 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 395

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VK++  
Sbjct: 396 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKTKT- 454

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 455 -AKLQDFKSFLLKDSETSQRLADLRQRVEQFARGFPMPGFDE 495

[70][TOP]
>UniRef100_UPI0000D9CD3C PREDICTED: similar to serine hydroxymethyltransferase 2
           (mitochondrial) isoform 2 n=1 Tax=Macaca mulatta
           RepID=UPI0000D9CD3C
          Length = 511

 Score =  172 bits (437), Expect = 2e-41
 Identities = 86/162 (53%), Positives = 114/162 (70%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 351 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 410

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VK++  
Sbjct: 411 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKTKT- 469

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 470 -AKLQDFKSFLLKDSETSQRLADLRQRVEQFARGFPMPGFDE 510

[71][TOP]
>UniRef100_UPI000181CA7E serine hydroxymethyltransferase 2 (mitochondrial) n=1 Tax=Pongo
           abelii RepID=UPI000181CA7E
          Length = 504

 Score =  172 bits (436), Expect = 2e-41
 Identities = 86/162 (53%), Positives = 113/162 (69%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 344 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 403

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VK +  
Sbjct: 404 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKRKT- 462

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 463 -AKLQDFKSFLLKDSETSQRLADLRQRVEQFARAFPMPGFDE 503

[72][TOP]
>UniRef100_UPI000155E566 PREDICTED: serine hydroxymethyltransferase 2 (mitochondrial) n=1
           Tax=Equus caballus RepID=UPI000155E566
          Length = 504

 Score =  172 bits (436), Expect = 2e-41
 Identities = 85/159 (53%), Positives = 114/159 (71%)
 Frame = -3

Query: 610 YKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIA 431
           ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V I 
Sbjct: 347 FREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSIT 406

Query: 430 SNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTK 251
           +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V+I L+VKS+    K
Sbjct: 407 ANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVSIGLEVKSKT--AK 464

Query: 250 LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
           L+DF S + +       +A LR  VE+FA+ FP  GF++
Sbjct: 465 LQDFKSFLLNDPETSRRLANLRQRVEQFARAFPMPGFDE 503

[73][TOP]
>UniRef100_A4S9F8 Serine hydroxymethyltransferase n=1 Tax=Ostreococcus lucimarinus
           CCE9901 RepID=A4S9F8_OSTLU
          Length = 455

 Score =  172 bits (436), Expect = 2e-41
 Identities = 84/155 (54%), Positives = 111/155 (71%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  +  YQEQV+ N A  A  LME GY LVSGGTDNHL+L +L+PKG+DG+RVEK+L+  
Sbjct: 295 TPGFVKYQEQVIKNCAAMANRLMELGYTLVSGGTDNHLILCDLRPKGVDGARVEKILDLS 354

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HI  NKN+VPGD SA++PGGIR+G+PA+T+RG  E DF +VA   D+ V IA+ +K + +
Sbjct: 355 HITLNKNSVPGDTSALIPGGIRIGSPAMTTRGMTEADFVRVANLIDQGVQIAIDIKKKTE 414

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQF 155
           G KLKDF + ++ +      IA LR EVE FA +F
Sbjct: 415 GGKLKDFKAYLDENDV--PAIAALRAEVEAFADEF 447

[74][TOP]
>UniRef100_Q5REZ8 Serine hydroxymethyltransferase n=1 Tax=Pongo abelii
           RepID=Q5REZ8_PONAB
          Length = 505

 Score =  172 bits (436), Expect = 2e-41
 Identities = 86/162 (53%), Positives = 113/162 (69%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 345 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 404

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VK +  
Sbjct: 405 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKRKT- 463

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 464 -AKLQDFKSFLLKDSETSQRLADLRQRVEQFARAFPMPGFDE 504

[75][TOP]
>UniRef100_UPI00005A1FE3 PREDICTED: similar to serine hydroxymethyltransferase 2
           (mitochondrial) isoform 2 n=1 Tax=Canis lupus familiaris
           RepID=UPI00005A1FE3
          Length = 505

 Score =  172 bits (435), Expect = 3e-41
 Identities = 86/162 (53%), Positives = 114/162 (70%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 345 TPTFREYALQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 404

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VK++  
Sbjct: 405 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVHIGLEVKNKT- 463

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 464 -AKLQDFKSFLLKDSETSHRLADLRQRVEQFARAFPMPGFDE 504

[76][TOP]
>UniRef100_B4DJQ3 Serine hydroxymethyltransferase n=1 Tax=Homo sapiens
           RepID=B4DJQ3_HUMAN
          Length = 483

 Score =  172 bits (435), Expect = 3e-41
 Identities = 86/162 (53%), Positives = 113/162 (69%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNH VLV+L+PKG+DG+R E+VLE V
Sbjct: 323 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHPVLVDLRPKGLDGARAERVLELV 382

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VKS+  
Sbjct: 383 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT- 441

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 442 -AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFDE 482

[77][TOP]
>UniRef100_B3RMF1 Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens
           RepID=B3RMF1_TRIAD
          Length = 532

 Score =  171 bits (432), Expect = 6e-41
 Identities = 86/159 (54%), Positives = 116/159 (72%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+  YQ+QVL N    A  L+ +GY L+SGGTDNHL+LV+L+PKG+DGSR E+VLE V
Sbjct: 373 TPEFVEYQKQVLKNCKAMANALLNKGYTLISGGTDNHLILVDLRPKGVDGSRTERVLELV 432

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           +I++NKNT PGD SA+ PGG+R+GTPALTSR F E+DF +V E+ ++ V I  + K +  
Sbjct: 433 NISTNKNTCPGDKSALFPGGMRLGTPALTSRDFKEKDFEQVVEFIERGVQITYEAKQKT- 491

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
           GT LK+F   + S   I ++I+ LR EV+EFA+QFP  G
Sbjct: 492 GT-LKEFKEFVISDPDITAKISALRQEVKEFAEQFPMPG 529

[78][TOP]
>UniRef100_A0BRC5 Chromosome undetermined scaffold_122, whole genome shotgun sequence
           n=1 Tax=Paramecium tetraurelia RepID=A0BRC5_PARTE
          Length = 474

 Score =  171 bits (432), Expect = 6e-41
 Identities = 85/161 (52%), Positives = 117/161 (72%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ+ VLSNS K A  L++R + LVSGGTDNHLVLVNLKPK IDG+RVE +L++V
Sbjct: 315 TPEFKNYQKNVLSNSKKLADELLKRNFSLVSGGTDNHLVLVNLKPKSIDGARVESILQSV 374

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           +I+ NKNTVP D SA+VP G+RMG+  +TSRG  +++FA++A++ D+ V IA KVK EA 
Sbjct: 375 NISVNKNTVPKDKSALVPNGLRMGSVPMTSRGVNQDEFAQIADFIDRGVAIAQKVKGEA- 433

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFE 137
           G K++DF   +  +     +I KL+ +V  F+ QFP  G +
Sbjct: 434 GPKVQDFKDWLAKNGDQHPDIQKLKKDVVSFSSQFPVPGLD 474

[79][TOP]
>UniRef100_B4DW25 Serine hydroxymethyltransferase n=1 Tax=Homo sapiens
           RepID=B4DW25_HUMAN
          Length = 430

 Score =  171 bits (432), Expect = 6e-41
 Identities = 85/153 (55%), Positives = 110/153 (71%)
 Frame = -3

Query: 592 QVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIASNKNTV 413
           QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V I +NKNT 
Sbjct: 279 QVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTC 338

Query: 412 PGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTKLKDFVS 233
           PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VKS+    KL+DF S
Sbjct: 339 PGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT--AKLQDFKS 396

Query: 232 AMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
            +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 397 FLLKDSETSQRLANLRQRVEQFARAFPMPGFDE 429

[80][TOP]
>UniRef100_A4QV83 Serine hydroxymethyltransferase n=1 Tax=Magnaporthe grisea
           RepID=A4QV83_MAGGR
          Length = 516

 Score =  170 bits (431), Expect = 8e-41
 Identities = 92/171 (53%), Positives = 122/171 (71%), Gaps = 17/171 (9%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMER-------GYELVSGGTDNHLVLVNLKPKGIDGSRVEK 455
           E++AYQEQVL N+  FA+ L E        GY++VSGGTDNHLVL +LKP+GIDG+RVE+
Sbjct: 340 EFRAYQEQVLVNAKAFARRLGEAKGNGGGLGYKIVSGGTDNHLVLADLKPQGIDGARVER 399

Query: 454 VLEAVHIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKV 275
           VLE V IA+NKNTVPGD SA+ PGG+RMGTPA+T+RGF E+DF +VA+  D+AVTIA++V
Sbjct: 400 VLELVGIAANKNTVPGDKSALTPGGLRMGTPAMTTRGFGEDDFVRVADIVDRAVTIAVRV 459

Query: 274 ----------KSEAQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 152
                     K E    KLK+F+  + +  T +SEI +LR EV ++   +P
Sbjct: 460 DKAARKAAEAKGEKSPGKLKNFLEYLGNGET-ESEIVQLRSEVSDWVGTYP 509

[81][TOP]
>UniRef100_C1N4T7 Serine hydroxymethyltransferase n=1 Tax=Micromonas pusilla CCMP1545
           RepID=C1N4T7_9CHLO
          Length = 509

 Score =  170 bits (430), Expect = 1e-40
 Identities = 85/155 (54%), Positives = 113/155 (72%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+  YQ+QV+SN A  A  L E GY LVSGGTDNHL+L +L+P G+DG+RVE +L+  
Sbjct: 350 TPEFIGYQKQVISNCATLANRLTELGYTLVSGGTDNHLILCDLRPMGVDGARVEYILDQA 409

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HI  NKN+VP D SA+VPGGIR+GTPA+T+RG +E+DF KVA+  D+ V IA+  K++A 
Sbjct: 410 HITLNKNSVPRDTSALVPGGIRIGTPAMTTRGMLEDDFVKVADLIDEGVKIAIDCKAQAG 469

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQF 155
           G KL DF   ++  ST +++IA LR +VE FA  F
Sbjct: 470 GPKLADFKQYVQ--STDRADIAALREKVESFAGDF 502

[82][TOP]
>UniRef100_A9T735 Serine hydroxymethyltransferase (Fragment) n=1 Tax=Physcomitrella
           patens subsp. patens RepID=A9T735_PHYPA
          Length = 460

 Score =  170 bits (430), Expect = 1e-40
 Identities = 87/166 (52%), Positives = 112/166 (67%), Gaps = 1/166 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ+QV+ N    A  LME GY+LVSGGTDNHLVLV+L+P G DG+R EKVL+  
Sbjct: 292 TPEFKTYQQQVVKNCRALADRLMELGYKLVSGGTDNHLVLVDLRPMGADGARAEKVLDLA 351

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I  NKN+VPGD SA+ PGG+R+G+PALT+RG  E +F KVA +  + + I +K K    
Sbjct: 352 SITLNKNSVPGDKSAINPGGVRIGSPALTTRGLGEAEFVKVANFIHEGIQITVKAKETCP 411

Query: 259 GTKLKDFVSAMESSSTIQ-SEIAKLRHEVEEFAKQFPTIGFEKETM 125
           GTK+KDF+  +ES S  Q   I  LR  VE FA Q+P  G   E++
Sbjct: 412 GTKIKDFLEYVESESCEQRGAILDLRKRVEAFATQYPIPGVGTESL 457

[83][TOP]
>UniRef100_UPI000023F3A5 hypothetical protein FG08350.1 n=1 Tax=Gibberella zeae PH-1
           RepID=UPI000023F3A5
          Length = 502

 Score =  169 bits (429), Expect = 1e-40
 Identities = 93/166 (56%), Positives = 119/166 (71%), Gaps = 10/166 (6%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQE+VL+NS   A  L + GY LVSGGTDNHLVLV+LKPKGIDG+RVE+VLE V
Sbjct: 332 TPEFKDYQEKVLANSQAMANQLTDLGYSLVSGGTDNHLVLVDLKPKGIDGARVERVLELV 391

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKV----- 275
            +ASNKNTVPGD SA+ PGG+R+GTPA+T+RGF  EDF +VA+  D+ V I L V     
Sbjct: 392 GVASNKNTVPGDRSALKPGGLRLGTPAMTTRGFNGEDFKRVADIVDRGVKITLAVDKDAR 451

Query: 274 -KSEAQGTK----LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 152
             +EA+G K    +K+F+  +   S+++ EIA LR EV E+   FP
Sbjct: 452 AAAEAKGAKNPGTVKNFLEFLGDGSSVK-EIAALRDEVAEWVGGFP 496

[84][TOP]
>UniRef100_B7PGD5 Serine hydroxymethyltransferase (Fragment) n=1 Tax=Ixodes
           scapularis RepID=B7PGD5_IXOSC
          Length = 475

 Score =  169 bits (429), Expect = 1e-40
 Identities = 87/162 (53%), Positives = 113/162 (69%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+KAYQEQV+ N+   A+ L  +GY  VSGGTDNHLV V+L+P G++GSR E+VLE +
Sbjct: 314 TPEFKAYQEQVVKNAKMLAKELQAKGYTCVSGGTDNHLVWVDLRPTGLNGSRAERVLELM 373

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            IA NKNTVPGD SA+ PGGIR+GTPALT+RG  E+D A VAE+  K +  AL+VK+   
Sbjct: 374 SIACNKNTVPGDKSALNPGGIRLGTPALTTRGLKEQDMATVAEFIHKGLQFALEVKA-GS 432

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
           G  LKDF + +E+       + +LR +VE FA  F   G+EK
Sbjct: 433 GPTLKDFKTKLETDPACVDRVRELREQVENFALTFFMPGYEK 474

[85][TOP]
>UniRef100_A0BLK1 Chromosome undetermined scaffold_114, whole genome shotgun sequence
           n=1 Tax=Paramecium tetraurelia RepID=A0BLK1_PARTE
          Length = 474

 Score =  169 bits (429), Expect = 1e-40
 Identities = 85/161 (52%), Positives = 116/161 (72%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K+YQ  VL NS K A  L++R + LVSGGTDNHLVLVNLKPK IDG+RVE +L+AV
Sbjct: 315 TPEFKSYQMSVLLNSKKLADELLKRNFSLVSGGTDNHLVLVNLKPKSIDGARVESILQAV 374

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           +I+ NKNTVP D SA+VP G+RMG+  +TSRG  +++FA++A++ D+ V IA KVK EA 
Sbjct: 375 NISVNKNTVPKDKSALVPNGLRMGSVPMTSRGVNQDEFAQIADFIDRGVAIAQKVKGEA- 433

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFE 137
           G K++DF   +  +     +I KL+ +V  F+ QFP  G +
Sbjct: 434 GPKVQDFKDWLAKNGDQHPDIQKLKKDVVSFSSQFPVPGLD 474

[86][TOP]
>UniRef100_UPI00005A1FE4 PREDICTED: similar to serine hydroxymethyltransferase 2
           (mitochondrial) isoform 4 n=1 Tax=Canis lupus familiaris
           RepID=UPI00005A1FE4
          Length = 505

 Score =  169 bits (428), Expect = 2e-40
 Identities = 85/156 (54%), Positives = 111/156 (71%)
 Frame = -3

Query: 601 YQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIASNK 422
           Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V I +NK
Sbjct: 351 YALQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANK 410

Query: 421 NTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTKLKD 242
           NT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VK++    KL+D
Sbjct: 411 NTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVHIGLEVKNKT--AKLQD 468

Query: 241 FVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
           F S +   S     +A LR  VE+FA+ FP  GF++
Sbjct: 469 FKSFLLKDSETSHRLADLRQRVEQFARAFPMPGFDE 504

[87][TOP]
>UniRef100_UPI000023F466 hypothetical protein FG09873.1 n=1 Tax=Gibberella zeae PH-1
           RepID=UPI000023F466
          Length = 499

 Score =  169 bits (428), Expect = 2e-40
 Identities = 92/172 (53%), Positives = 119/172 (69%), Gaps = 16/172 (9%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMER------GYELVSGGTDNHLVLVNLKPKGIDGSRVE 458
           T E++AYQ QVL N+  FA+ L E       GY+LVSGGTDNHLVL +LKP GIDG RVE
Sbjct: 322 TPEFQAYQSQVLKNAKAFAKRLSEPKGKGGLGYKLVSGGTDNHLVLADLKPHGIDGGRVE 381

Query: 457 KVLEAVHIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALK 278
           +VLE V +A+NKNTVPGD SA+VPGG+RMGTPA+T+RGF E+DF +VA+  D+AVTIA +
Sbjct: 382 RVLELVGVAANKNTVPGDRSALVPGGLRMGTPAMTTRGFNEDDFVRVADVVDRAVTIASR 441

Query: 277 V----------KSEAQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 152
           +          K +    K+K F+  +    T QSEI +LR EVE++   +P
Sbjct: 442 IDKAARKAAEEKGDKSPGKIKVFLEHLGDGET-QSEIVQLRSEVEDWVGTYP 492

[88][TOP]
>UniRef100_A9T736 Serine hydroxymethyltransferase n=1 Tax=Physcomitrella patens
           subsp. patens RepID=A9T736_PHYPA
          Length = 582

 Score =  169 bits (427), Expect = 2e-40
 Identities = 87/164 (53%), Positives = 110/164 (67%), Gaps = 1/164 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ+QV+ N    A  LME GY+LVSGGTDNHLVLV+L+P G DG+R EKVL+  
Sbjct: 373 TPEFKTYQQQVVKNCRALADRLMELGYKLVSGGTDNHLVLVDLRPMGADGARAEKVLDLA 432

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I  NKN+VPGD SA+ PGG+R+G+PALT+RG  E +F KVA +  + + I +K K    
Sbjct: 433 SITLNKNSVPGDKSAINPGGVRIGSPALTTRGLGEAEFVKVANFIHEGIQITVKAKETCP 492

Query: 259 GTKLKDFVSAMESSSTIQ-SEIAKLRHEVEEFAKQFPTIGFEKE 131
           GTK+KDF+  +ES S  Q   I  LR  VE FA Q+P  G   E
Sbjct: 493 GTKIKDFLEYVESESCEQRGAILDLRKRVEAFATQYPIPGVGTE 536

[89][TOP]
>UniRef100_A8J4R9 Serine hydroxymethyltransferase n=1 Tax=Chlamydomonas reinhardtii
           RepID=A8J4R9_CHLRE
          Length = 487

 Score =  169 bits (427), Expect = 2e-40
 Identities = 87/161 (54%), Positives = 117/161 (72%), Gaps = 2/161 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E++ YQ+QV++N +     L + GY++VS GTDNHLVL++LKP GIDG+RV+ VL+AV
Sbjct: 327 TEEFRTYQKQVVANCSALCGRLQQHGYKIVSDGTDNHLVLLDLKPAGIDGARVQTVLDAV 386

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIA--LKVKSE 266
            I  NKN+VPGD SAMVPGGIR+GTPALT+RGF E+DF +VA++  +A+TIA   + K+ 
Sbjct: 387 SITLNKNSVPGDKSAMVPGGIRIGTPALTTRGFQEKDFEQVADFIHRAITIAKDCQAKTP 446

Query: 265 AQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
           A G KLK+F   +E +   + +IA LR EVE  A  FP  G
Sbjct: 447 APG-KLKEFKEYLEGAGAARPDIAALRAEVEALATSFPMPG 486

[90][TOP]
>UniRef100_UPI000151B2B1 conserved hypothetical protein n=1 Tax=Pichia guilliermondii ATCC
           6260 RepID=UPI000151B2B1
          Length = 484

 Score =  168 bits (426), Expect = 3e-40
 Identities = 78/157 (49%), Positives = 117/157 (74%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           EYK YQ+ V+ N++ FAQ L  RG++LVSGGTD HLVL++L  K IDG+RVE +LE ++I
Sbjct: 326 EYKQYQQNVIDNASSFAQALQSRGFKLVSGGTDTHLVLIDLSSKNIDGARVEGLLERINI 385

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           A+NKNTVPGD SA+ P G+R+GTPA+T+RGF + +F KVAEY ++AV ++LK+K + QG+
Sbjct: 386 AANKNTVPGDKSALFPSGLRVGTPAMTTRGFGQAEFEKVAEYINRAVELSLKLKGQEQGS 445

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
             K+ +++ +  +   +E+ +L  EV ++  Q+P  G
Sbjct: 446 VPKELLASFKQLADESTEVKELAEEVAKWVGQYPVPG 482

[91][TOP]
>UniRef100_Q5C0V4 SJCHGC07535 protein (Fragment) n=1 Tax=Schistosoma japonicum
           RepID=Q5C0V4_SCHJA
          Length = 218

 Score =  168 bits (426), Expect = 3e-40
 Identities = 82/159 (51%), Positives = 112/159 (70%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           EY+ YQEQVL N  +  ++L + GYELV+GG+D HL L++L+P  IDG+R EK+LE V I
Sbjct: 59  EYRVYQEQVLKNMKQLCKSLTDYGYELVTGGSDTHLCLIDLRPLKIDGARAEKILELVRI 118

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           A+NKNT PGD+SA+ PGG+R G+ ALTSR F E+DF KVAE+    + IA+K    A   
Sbjct: 119 AANKNTCPGDLSALRPGGLRFGSAALTSRNFREKDFIKVAEFIHTGIQIAVKANELANSK 178

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFE 137
            LKD+   +E++  I+S I KLR E+EEFA ++P  G +
Sbjct: 179 LLKDYEVVVETNVEIRSMIGKLRREIEEFASKYPLPGLD 217

[92][TOP]
>UniRef100_A5DQR0 Serine hydroxymethyltransferase n=1 Tax=Pichia guilliermondii
           RepID=A5DQR0_PICGU
          Length = 484

 Score =  168 bits (426), Expect = 3e-40
 Identities = 78/157 (49%), Positives = 117/157 (74%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           EYK YQ+ V+ N++ FAQ L  RG++LVSGGTD HLVL++L  K IDG+RVE +LE ++I
Sbjct: 326 EYKQYQQNVIDNASSFAQALQSRGFKLVSGGTDTHLVLIDLSSKNIDGARVEGLLERINI 385

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           A+NKNTVPGD SA+ P G+R+GTPA+T+RGF + +F KVAEY ++AV ++LK+K + QG+
Sbjct: 386 AANKNTVPGDKSALFPSGLRVGTPAMTTRGFGQAEFEKVAEYINRAVELSLKLKGQEQGS 445

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
             K+ +++ +  +   +E+ +L  EV ++  Q+P  G
Sbjct: 446 VPKELLASFKQLADESTEVKELAEEVAKWVGQYPVPG 482

[93][TOP]
>UniRef100_C1EJ55 Serine hydroxymethyltransferase n=1 Tax=Micromonas sp. RCC299
           RepID=C1EJ55_9CHLO
          Length = 433

 Score =  168 bits (425), Expect = 4e-40
 Identities = 83/155 (53%), Positives = 112/155 (72%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+  YQ+QV+ N A  A  L E GY LVSGGTDNHL+L +L+PKGIDG+RVE++L+  
Sbjct: 274 TPEFVEYQKQVVKNCAALAGRLTELGYTLVSGGTDNHLILCDLRPKGIDGARVERILDLA 333

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HI  NKN+VP D SA++PGGIR+G PA+T+RG +EEDF +VA+   K V IA++ K+ A+
Sbjct: 334 HITLNKNSVPRDTSALIPGGIRIGAPAMTTRGMLEEDFVRVADLIHKGVEIAIECKAAAE 393

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQF 155
           G KLKDF   + ++   +++I  LR EVE FA  F
Sbjct: 394 GPKLKDFNDYLAAND--RADIKALREEVESFADGF 426

[94][TOP]
>UniRef100_C4QPI2 Serine hydroxymethyltransferase n=1 Tax=Schistosoma mansoni
           RepID=C4QPI2_SCHMA
          Length = 458

 Score =  168 bits (425), Expect = 4e-40
 Identities = 84/159 (52%), Positives = 112/159 (70%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           EYK YQEQVL N  +  ++L   GYELV+GG+D HL L++L+P  IDG+R EKVLE V I
Sbjct: 299 EYKVYQEQVLKNMKQLCKSLKAYGYELVTGGSDTHLCLLDLRPLKIDGARAEKVLELVRI 358

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           A+NKNT PGDVSA+ PGG+R G+ ALTSR F EEDF KV+E+   A+ IA+K    A   
Sbjct: 359 AANKNTCPGDVSALRPGGLRFGSAALTSRNFHEEDFVKVSEFIHVAIQIAVKANELASSK 418

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFE 137
            LKD+   +E++  ++S I KL+ E+EEFA ++P  G +
Sbjct: 419 LLKDYEVVVETNVEVRSMIEKLKLEIEEFASKYPLPGLD 457

[95][TOP]
>UniRef100_P14519 Serine hydroxymethyltransferase, mitochondrial n=1 Tax=Oryctolagus
           cuniculus RepID=GLYM_RABIT
          Length = 504

 Score =  168 bits (425), Expect = 4e-40
 Identities = 84/160 (52%), Positives = 110/160 (68%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L+ERGY LVSGGTDNHLVLV+L+PKG+DG+R E+VLE V
Sbjct: 344 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 403

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VK +  
Sbjct: 404 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKRKT- 462

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGF 140
             KL+DF S +         +A LR  V++FA+ FP  GF
Sbjct: 463 -AKLQDFKSFLLKDPETSQHLADLRRRVQQFARAFPMPGF 501

[96][TOP]
>UniRef100_Q9CZN7 Serine hydroxymethyltransferase n=1 Tax=Mus musculus
           RepID=Q9CZN7_MOUSE
          Length = 504

 Score =  167 bits (422), Expect = 8e-40
 Identities = 83/162 (51%), Positives = 112/162 (69%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L++RGY LVSGGTD HLVLV+L+PKG+DG+R E+VLE V
Sbjct: 344 TPMFREYSLQVLRNAQAMADALLKRGYSLVSGGTDTHLVLVDLRPKGLDGARAERVLELV 403

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VK +  
Sbjct: 404 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKRKT- 462

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +         +A LR +VE+FA+ FP  GF++
Sbjct: 463 -AKLQDFKSFLLKDPETSQRLANLRQQVEQFARGFPMPGFDE 503

[97][TOP]
>UniRef100_Q99K87 Serine hydroxymethyltransferase n=1 Tax=Mus musculus
           RepID=Q99K87_MOUSE
          Length = 504

 Score =  167 bits (422), Expect = 8e-40
 Identities = 83/162 (51%), Positives = 112/162 (69%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L++RGY LVSGGTD HLVLV+L+PKG+DG+R E+VLE V
Sbjct: 344 TPMFREYSLQVLRNAQAMADALLKRGYSLVSGGTDTHLVLVDLRPKGLDGARAERVLELV 403

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VK +  
Sbjct: 404 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKRKT- 462

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +         +A LR +VE+FA+ FP  GF++
Sbjct: 463 -AKLQDFKSFLLKDPETSQRLANLRQQVEQFARGFPMPGFDE 503

[98][TOP]
>UniRef100_Q5U3Z7 Serine hydroxymethyltransferase n=1 Tax=Rattus norvegicus
           RepID=Q5U3Z7_RAT
          Length = 504

 Score =  167 bits (422), Expect = 8e-40
 Identities = 83/162 (51%), Positives = 112/162 (69%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L++RGY LVSGGTD HLVLV+L+PKG+DG+R E+VLE V
Sbjct: 344 TPMFREYSLQVLRNAQAMADALLKRGYSLVSGGTDTHLVLVDLRPKGLDGARAERVLELV 403

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VK +  
Sbjct: 404 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKRKT- 462

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +         +A LR +VE+FA+ FP  GF++
Sbjct: 463 -AKLQDFKSFLLKDPETSQRLANLRQQVEQFARGFPMPGFDE 503

[99][TOP]
>UniRef100_Q3TFD0 Serine hydroxymethyltransferase n=1 Tax=Mus musculus
           RepID=Q3TFD0_MOUSE
          Length = 501

 Score =  167 bits (422), Expect = 8e-40
 Identities = 83/162 (51%), Positives = 112/162 (69%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QVL N+   A  L++RGY LVSGGTD HLVLV+L+PKG+DG+R E+VLE V
Sbjct: 341 TPMFREYSLQVLRNAQAMADALLKRGYSLVSGGTDTHLVLVDLRPKGLDGARAERVLELV 400

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D+ V I L+VK +  
Sbjct: 401 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKRKT- 459

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             KL+DF S +         +A LR +VE+FA+ FP  GF++
Sbjct: 460 -AKLQDFKSFLLKDPETSQRLANLRQQVEQFARGFPMPGFDE 500

[100][TOP]
>UniRef100_C7YT82 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
           RepID=C7YT82_NECH7
          Length = 498

 Score =  167 bits (422), Expect = 8e-40
 Identities = 91/172 (52%), Positives = 118/172 (68%), Gaps = 16/172 (9%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMER------GYELVSGGTDNHLVLVNLKPKGIDGSRVE 458
           T E++ YQ QVL N+  FA+ L E       GY LVSGGTDNHLVL +LKP+GIDGSRVE
Sbjct: 322 TPEFQVYQTQVLKNAKAFARRLSEPKGNGGLGYTLVSGGTDNHLVLADLKPQGIDGSRVE 381

Query: 457 KVLEAVHIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALK 278
           +VLE V +A+NKNTVPGD SA+VPGG+RMGTPA+T+RGF E+DF +VA+  D+AV I  +
Sbjct: 382 RVLELVGVAANKNTVPGDRSALVPGGLRMGTPAMTTRGFNEDDFVRVADVVDRAVAITSR 441

Query: 277 V----------KSEAQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 152
           +          K E    KLK+F+  + +  T QSEI +LR EV ++   +P
Sbjct: 442 IDKAARKEAEEKGEKNPGKLKNFMEYLGNGET-QSEIVQLRSEVADWVGTYP 492

[101][TOP]
>UniRef100_UPI00006A0CB2 Shmt2-prov protein. n=1 Tax=Xenopus (Silurana) tropicalis
           RepID=UPI00006A0CB2
          Length = 496

 Score =  166 bits (421), Expect = 1e-39
 Identities = 83/159 (52%), Positives = 109/159 (68%)
 Frame = -3

Query: 610 YKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIA 431
           ++ Y  QVL N+   A  L+ +GY LVSGGTDNHLVLV+L+PKGIDG+R E+VLE V I 
Sbjct: 339 FREYAVQVLKNAKSMAAALLSKGYTLVSGGTDNHLVLVDLRPKGIDGARAERVLELVSIT 398

Query: 430 SNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTK 251
           +NKNT PGD SA+ PGG+R+G PALTSR F E DF KV  + D+ + I L VK +    K
Sbjct: 399 ANKNTCPGDKSALTPGGLRLGAPALTSRNFKEADFEKVVHFIDEGIRIGLDVKRKT--NK 456

Query: 250 LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
           L+DF + +       + IA LR +VE+FA+ FP  GF++
Sbjct: 457 LQDFKNFLLEDHETVNRIADLRKQVEQFARSFPMPGFDE 495

[102][TOP]
>UniRef100_Q68EQ3 Serine hydroxymethyltransferase n=1 Tax=Xenopus (Silurana)
           tropicalis RepID=Q68EQ3_XENTR
          Length = 496

 Score =  166 bits (421), Expect = 1e-39
 Identities = 83/159 (52%), Positives = 109/159 (68%)
 Frame = -3

Query: 610 YKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIA 431
           ++ Y  QVL N+   A  L+ +GY LVSGGTDNHLVLV+L+PKGIDG+R E+VLE V I 
Sbjct: 339 FREYAVQVLKNAKSMAAALLSKGYTLVSGGTDNHLVLVDLRPKGIDGARAERVLELVSIT 398

Query: 430 SNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTK 251
           +NKNT PGD SA+ PGG+R+G PALTSR F E DF KV  + D+ + I L VK +    K
Sbjct: 399 ANKNTCPGDKSALTPGGLRLGAPALTSRNFKEADFEKVVHFIDEGIRIGLDVKRKT--NK 456

Query: 250 LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
           L+DF + +       + IA LR +VE+FA+ FP  GF++
Sbjct: 457 LQDFKNFLLEDHETVNRIADLRKQVEQFARSFPMPGFDE 495

[103][TOP]
>UniRef100_Q7S5N8 Putative serine hydroxymethyltransferase, mitochondrial n=1
           Tax=Neurospora crassa RepID=GLYM_NEUCR
          Length = 527

 Score =  166 bits (421), Expect = 1e-39
 Identities = 88/173 (50%), Positives = 119/173 (68%), Gaps = 17/173 (9%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMER------GYELVSGGTDNHLVLVNLKPKGIDGSRVE 458
           T E++AYQ QVL+N+   A  L E       GY +VSGGTDNHLVL++LKP+GIDGSRVE
Sbjct: 349 TPEFRAYQSQVLANATALAARLGEPKDKNGLGYTIVSGGTDNHLVLIDLKPQGIDGSRVE 408

Query: 457 KVLEAVHIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALK 278
           +VLE V +A+NKNTVPGD SA+ PGG+R+GTPA+T+RGF EEDFA+VA+  D+AVTIA++
Sbjct: 409 RVLELVGVAANKNTVPGDKSALTPGGLRIGTPAMTTRGFTEEDFARVADIIDRAVTIAVR 468

Query: 277 VK-----------SEAQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 152
           +            +E    ++K F+  + +  T   EI +LR EVE +   +P
Sbjct: 469 INKAAKEDAVKKGNEKAANRVKTFMDYLGNGET-DPEIVQLRSEVESWVGTYP 520

[104][TOP]
>UniRef100_UPI00017B4846 UPI00017B4846 related cluster n=1 Tax=Tetraodon nigroviridis
           RepID=UPI00017B4846
          Length = 484

 Score =  166 bits (420), Expect = 1e-39
 Identities = 80/158 (50%), Positives = 112/158 (70%), Gaps = 1/158 (0%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+KAYQ QVL+N    +  L++ GY++V+GG+DNHL+L++L+ KG DG R EKVLEA  I
Sbjct: 323 EFKAYQVQVLANCRALSSALIDHGYKIVTGGSDNHLILLDLRSKGTDGGRAEKVLEACAI 382

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ-G 257
           A NKNT PGD SA+ P G+R G+PALTSRG V++DF KVAE+  +A+ ++L+V+      
Sbjct: 383 ACNKNTCPGDKSALRPSGLRFGSPALTSRGLVQDDFKKVAEFIHRAIMLSLEVQGSLDPK 442

Query: 256 TKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
             LK+F+ A++     Q  +A++R EVE FA QFP  G
Sbjct: 443 APLKEFIQALKQEEKFQQRVAEIRTEVEAFASQFPMPG 480

[105][TOP]
>UniRef100_Q4SVN9 Serine hydroxymethyltransferase (Fragment) n=1 Tax=Tetraodon
           nigroviridis RepID=Q4SVN9_TETNG
          Length = 482

 Score =  166 bits (420), Expect = 1e-39
 Identities = 80/158 (50%), Positives = 112/158 (70%), Gaps = 1/158 (0%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+KAYQ QVL+N    +  L++ GY++V+GG+DNHL+L++L+ KG DG R EKVLEA  I
Sbjct: 321 EFKAYQVQVLANCRALSSALIDHGYKIVTGGSDNHLILLDLRSKGTDGGRAEKVLEACAI 380

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ-G 257
           A NKNT PGD SA+ P G+R G+PALTSRG V++DF KVAE+  +A+ ++L+V+      
Sbjct: 381 ACNKNTCPGDKSALRPSGLRFGSPALTSRGLVQDDFKKVAEFIHRAIMLSLEVQGSLDPK 440

Query: 256 TKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
             LK+F+ A++     Q  +A++R EVE FA QFP  G
Sbjct: 441 APLKEFIQALKQEEKFQQRVAEIRTEVEAFASQFPMPG 478

[106][TOP]
>UniRef100_B2ADB9 Serine hydroxymethyltransferase n=1 Tax=Podospora anserina
           RepID=B2ADB9_PODAN
          Length = 544

 Score =  166 bits (420), Expect = 1e-39
 Identities = 88/173 (50%), Positives = 121/173 (69%), Gaps = 17/173 (9%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMER------GYELVSGGTDNHLVLVNLKPKGIDGSRVE 458
           T E++AYQ QVLSN+  F++ L E       GY++VSGGTDNHLVLV+LKP G+DG+RVE
Sbjct: 367 TPEFRAYQSQVLSNAKAFSKRLGEPKEKGGLGYKIVSGGTDNHLVLVDLKPHGVDGARVE 426

Query: 457 KVLEAVHIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALK 278
           ++LE V +ASNKNTVPGD SA+ PGG+RMGTPA+T+RGF EEDFA+VA+  D++VTIA++
Sbjct: 427 RILELVGVASNKNTVPGDKSALTPGGLRMGTPAMTTRGFQEEDFARVADIVDRSVTIAVR 486

Query: 277 VKSEAQ-----------GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 152
           V   A+             ++K F+  +    T  +EI +LR EV ++   +P
Sbjct: 487 VDKAARKAAEEKGEGKTAGRVKTFMEFLGDGET-DTEIVQLRSEVADWVGTYP 538

[107][TOP]
>UniRef100_Q6AXB3 Serine hydroxymethyltransferase n=1 Tax=Xenopus laevis
           RepID=Q6AXB3_XENLA
          Length = 496

 Score =  165 bits (418), Expect = 2e-39
 Identities = 82/159 (51%), Positives = 108/159 (67%)
 Frame = -3

Query: 610 YKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIA 431
           ++ Y  QVL N+   A  L+ +GY LVSGGTDNHLVLV+L+PKGIDG+R E+VLE V I 
Sbjct: 339 FREYAVQVLKNAKSMAAALLSKGYTLVSGGTDNHLVLVDLRPKGIDGARAERVLELVSIT 398

Query: 430 SNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTK 251
           +NKNT PGD SA+ PGG+R+G PALTSR F E DF KV ++ D+ + I L VK +    K
Sbjct: 399 ANKNTCPGDKSALTPGGLRLGAPALTSRNFKEADFEKVVDFIDEGIRIGLDVKRKT--NK 456

Query: 250 LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
           L+DF + +         I  LR +VE+FA+ FP  GF++
Sbjct: 457 LQDFKNFLLEDQETVKRIGDLRKQVEQFARAFPMPGFDE 495

[108][TOP]
>UniRef100_C4Y365 Serine hydroxymethyltransferase n=1 Tax=Clavispora lusitaniae ATCC
           42720 RepID=C4Y365_CLAL4
          Length = 530

 Score =  165 bits (418), Expect = 2e-39
 Identities = 79/157 (50%), Positives = 114/157 (72%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           EYK YQ++V+ N+  FA  L  +G++LVS GTD HL+LV+L+ K IDG+RVE VLE  +I
Sbjct: 372 EYKQYQQEVVDNAKAFADALKGKGFDLVSDGTDTHLILVDLRSKKIDGARVEAVLERANI 431

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           A+NKNTVPGD SA+ P G+R+GTPA+T+RGF  E+FAKVAEYF +AV IA+ +K + +G 
Sbjct: 432 AANKNTVPGDKSALFPSGLRVGTPAMTTRGFGPEEFAKVAEYFQRAVEIAISLKEKEEGA 491

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
             K+ +++ +  +   +E+  L  EV+ +A Q+P  G
Sbjct: 492 VAKELLASFKKLADESAEVKALDEEVKAWAAQYPVPG 528

[109][TOP]
>UniRef100_UPI0001865040 hypothetical protein BRAFLDRAFT_124997 n=1 Tax=Branchiostoma
           floridae RepID=UPI0001865040
          Length = 509

 Score =  165 bits (417), Expect = 3e-39
 Identities = 83/161 (51%), Positives = 111/161 (68%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ YQEQV+SN+   A++LM +GY+LVS GTDNHLVLV+L+PKGIDG+RVE+V E  
Sbjct: 348 TPMFREYQEQVMSNTKAMAESLMSKGYKLVSDGTDNHLVLVDLRPKGIDGARVERVCELA 407

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I  NKNT PGD SA+ PGG+R+G PALTSR   E++F +V ++ D+AV I L+VK +  
Sbjct: 408 SITCNKNTCPGDKSALTPGGLRLGAPALTSRCMKEDNFRQVVDFIDEAVQIGLQVKDKT- 466

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFE 137
           G K+ DF   +         I+ LR  VE FA+ FP  GF+
Sbjct: 467 GPKMVDFKKFLLEDEETVGRISDLRARVESFARTFPMPGFD 507

[110][TOP]
>UniRef100_UPI00016E0052 UPI00016E0052 related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E0052
          Length = 486

 Score =  165 bits (417), Expect = 3e-39
 Identities = 79/161 (49%), Positives = 112/161 (69%), Gaps = 1/161 (0%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+KAYQ QVL+N    +  L++ GY++V+GG+DNHL+L++L+ KG DG R EKVLEA  I
Sbjct: 325 EFKAYQMQVLANCKALSSALIDHGYKIVTGGSDNHLILLDLRSKGTDGGRAEKVLEACAI 384

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ-G 257
           A NKNT PGD SA+ P G+R G+PALTSRG V++DF KVAE+  + + + L+V+      
Sbjct: 385 ACNKNTCPGDKSALRPSGLRFGSPALTSRGMVQDDFKKVAEFIHRGIVLTLEVQGSLDPK 444

Query: 256 TKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             L+DF+ A++     Q  +A++R EVE FA QFP  G ++
Sbjct: 445 APLRDFLQALKREEKFQQRVAEIRTEVEAFASQFPMPGLDE 485

[111][TOP]
>UniRef100_UPI00016E0051 UPI00016E0051 related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E0051
          Length = 478

 Score =  165 bits (417), Expect = 3e-39
 Identities = 79/161 (49%), Positives = 112/161 (69%), Gaps = 1/161 (0%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+KAYQ QVL+N    +  L++ GY++V+GG+DNHL+L++L+ KG DG R EKVLEA  I
Sbjct: 317 EFKAYQMQVLANCKALSSALIDHGYKIVTGGSDNHLILLDLRSKGTDGGRAEKVLEACAI 376

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ-G 257
           A NKNT PGD SA+ P G+R G+PALTSRG V++DF KVAE+  + + + L+V+      
Sbjct: 377 ACNKNTCPGDKSALRPSGLRFGSPALTSRGMVQDDFKKVAEFIHRGIVLTLEVQGSLDPK 436

Query: 256 TKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
             L+DF+ A++     Q  +A++R EVE FA QFP  G ++
Sbjct: 437 APLRDFLQALKREEKFQQRVAEIRTEVEAFASQFPMPGLDE 477

[112][TOP]
>UniRef100_C3Y126 Serine hydroxymethyltransferase n=1 Tax=Branchiostoma floridae
           RepID=C3Y126_BRAFL
          Length = 509

 Score =  165 bits (417), Expect = 3e-39
 Identities = 83/161 (51%), Positives = 111/161 (68%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ YQEQV+SN+   A++LM +GY+LVS GTDNHLVLV+L+PKGIDG+RVE+V E  
Sbjct: 348 TPMFREYQEQVMSNTKAMAESLMSKGYKLVSDGTDNHLVLVDLRPKGIDGARVERVCELA 407

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I  NKNT PGD SA+ PGG+R+G PALTSR   E++F +V ++ D+AV I L+VK +  
Sbjct: 408 SITCNKNTCPGDKSALTPGGLRLGAPALTSRCMKEDNFRQVVDFIDEAVQIGLQVKDKT- 466

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFE 137
           G K+ DF   +         I+ LR  VE FA+ FP  GF+
Sbjct: 467 GPKMVDFKKFLLEDEETVGRISDLRARVESFARTFPMPGFD 507

[113][TOP]
>UniRef100_C6ZJY9 Serine hydroxymethyltransferase n=1 Tax=Glycine max
           RepID=C6ZJY9_SOYBN
          Length = 536

 Score =  164 bits (415), Expect = 5e-39
 Identities = 79/158 (50%), Positives = 116/158 (73%), Gaps = 1/158 (0%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+K YQ QV++N    A+ L+E GY+LVSGG+DNHLVLV+L+P G+DG+RVEK+L+   I
Sbjct: 378 EFKNYQNQVVANCRALAKRLIEHGYKLVSGGSDNHLVLVDLRPSGLDGARVEKILDLASI 437

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
             NKN+VPGD SA+VPGGIR+G PA+T+RG  E++F+ +A++  + V I+L+ KS   GT
Sbjct: 438 TLNKNSVPGDKSALVPGGIRIGAPAMTTRGLGEKEFSLIADFIHEGVQISLEAKSLVSGT 497

Query: 253 KLKDFVSAMESSS-TIQSEIAKLRHEVEEFAKQFPTIG 143
           KL+DF+  + SS   +  ++++LR +VE    Q+P  G
Sbjct: 498 KLQDFLKFVTSSEFPLGEKVSELRRKVEALTTQYPIPG 535

[114][TOP]
>UniRef100_C5MGE8 Serine hydroxymethyltransferase n=1 Tax=Candida tropicalis MYA-3404
           RepID=C5MGE8_CANTT
          Length = 491

 Score =  164 bits (414), Expect = 7e-39
 Identities = 77/157 (49%), Positives = 115/157 (73%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           EYK YQ+ V+SN+  FA  L+ +G++LVS GTD HL+LV+L+ + IDG+RVE VLE  +I
Sbjct: 333 EYKQYQQDVISNAKHFADALVSKGFKLVSDGTDTHLILVDLRSRNIDGARVEAVLERANI 392

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           A+NKNTVPGDVSA+ P G+R+GTPA+T+RGF  E+F KVAE+ DKAV IA+++K++ QG 
Sbjct: 393 AANKNTVPGDVSALFPSGLRVGTPAMTTRGFGPEEFDKVAEFIDKAVNIAIELKAQEQGK 452

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
             K+ +++ +  +    ++ +L  EV  +  ++P  G
Sbjct: 453 VPKELLASFKKLADESDKVKELDQEVVSWVSKYPVPG 489

[115][TOP]
>UniRef100_UPI00003BD7A0 hypothetical protein DEHA0C14113g n=1 Tax=Debaryomyces hansenii
           CBS767 RepID=UPI00003BD7A0
          Length = 493

 Score =  163 bits (413), Expect = 9e-39
 Identities = 75/157 (47%), Positives = 116/157 (73%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+K YQ+ V++N+A FA  L  +G+ LVSGGTD HL+LV+L+ K IDG+RVE VLE  +I
Sbjct: 334 EFKEYQKDVVANAASFASELQSKGFTLVSGGTDTHLILVDLRSKNIDGARVEAVLERANI 393

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           A+NKNTVPGD SA+ P G+R+GTPA+T+RGF   +FA+VAE+F++AV I++ +K++ QG+
Sbjct: 394 AANKNTVPGDKSALFPSGLRVGTPAMTTRGFGASEFARVAEFFERAVQISIDLKAQEQGS 453

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
             K+ +++ +  +   S + +L  EV+++   +P  G
Sbjct: 454 SSKELLASFKQLANSSSAVQELATEVKDWVSTYPVPG 490

[116][TOP]
>UniRef100_UPI00017B1AF2 UPI00017B1AF2 related cluster n=1 Tax=Tetraodon nigroviridis
           RepID=UPI00017B1AF2
          Length = 500

 Score =  163 bits (413), Expect = 9e-39
 Identities = 84/160 (52%), Positives = 110/160 (68%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  +K Y  QV+ N+   AQ L+++GY LVSGGTDNHLVLV+L+P+G+DG+R E+VLE V
Sbjct: 340 TPMFKQYIAQVMLNAKSMAQALLKKGYTLVSGGTDNHLVLVDLRPRGMDGARAERVLELV 399

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+GTPALTSR F E DF KV E+ D+ + IAL VK +  
Sbjct: 400 SITANKNTCPGDKSALTPGGLRLGTPALTSRQFKEADFEKVVEFIDEGIQIALDVKKKT- 458

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGF 140
              L  F + +   +   S +A+LR  VE FA+ FP  GF
Sbjct: 459 -GNLASFKAFLLEDAESVSRMAELRQRVELFARPFPMPGF 497

[117][TOP]
>UniRef100_Q4S803 Serine hydroxymethyltransferase n=1 Tax=Tetraodon nigroviridis
           RepID=Q4S803_TETNG
          Length = 500

 Score =  163 bits (413), Expect = 9e-39
 Identities = 84/160 (52%), Positives = 110/160 (68%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  +K Y  QV+ N+   AQ L+++GY LVSGGTDNHLVLV+L+P+G+DG+R E+VLE V
Sbjct: 340 TPMFKQYIAQVMLNAKSMAQALLKKGYTLVSGGTDNHLVLVDLRPRGMDGARAERVLELV 399

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+GTPALTSR F E DF KV E+ D+ + IAL VK +  
Sbjct: 400 SITANKNTCPGDKSALTPGGLRLGTPALTSRQFKEADFEKVVEFIDEGIQIALDVKKKT- 458

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGF 140
              L  F + +   +   S +A+LR  VE FA+ FP  GF
Sbjct: 459 -GNLASFKAFLLEDAESVSRMAELRQRVELFARPFPMPGF 497

[118][TOP]
>UniRef100_B9S1D7 Serine hydroxymethyltransferase n=1 Tax=Ricinus communis
           RepID=B9S1D7_RICCO
          Length = 527

 Score =  163 bits (413), Expect = 9e-39
 Identities = 81/158 (51%), Positives = 112/158 (70%), Gaps = 1/158 (0%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+KAYQ+QV+SN    A  L+E GY+LVSGG+DNHLVLV+L+P GIDG+RVEK+L+   I
Sbjct: 369 EFKAYQKQVISNCRALAYRLVELGYKLVSGGSDNHLVLVDLRPLGIDGARVEKILDMASI 428

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
             NKN+VPGD SA+VPGGIR+G+PA+T+RGF E +F   A++  + V I  + K    G+
Sbjct: 429 TLNKNSVPGDKSALVPGGIRIGSPAMTTRGFTEREFIATADFIHEGVQITTEAKKSVSGS 488

Query: 253 KLKDFVSAMESSS-TIQSEIAKLRHEVEEFAKQFPTIG 143
           KL+DF+  + S   ++ SE++ L+  VE  A QF   G
Sbjct: 489 KLQDFMKLVASPDFSLASEVSDLQTRVEALATQFSIPG 526

[119][TOP]
>UniRef100_A9PL11 Serine hydroxymethyltransferase n=1 Tax=Populus tremuloides
           RepID=A9PL11_POPTM
          Length = 529

 Score =  163 bits (413), Expect = 9e-39
 Identities = 78/158 (49%), Positives = 112/158 (70%), Gaps = 1/158 (0%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+KAYQ+QV+ NS   A  ++E GY+LVSGG+DNHL+LV+L+P G+DG+RVEK+L+   I
Sbjct: 371 EFKAYQKQVICNSRALANRMVELGYKLVSGGSDNHLILVDLRPLGLDGARVEKILDIASI 430

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
             NKN+VPGD SA+VPGGIR+G+PA+T+RGF E +F   A+   + V I+L+ K    G+
Sbjct: 431 TLNKNSVPGDKSALVPGGIRIGSPAMTTRGFTEREFVATADLIHEGVQISLEAKKSVSGS 490

Query: 253 KLKDFVSAMESSS-TIQSEIAKLRHEVEEFAKQFPTIG 143
           KL+DF+  ++S    +  +++ LR  VE    QFP  G
Sbjct: 491 KLQDFLKFVKSPDFPLTDKVSDLRRRVEALTTQFPIPG 528

[120][TOP]
>UniRef100_P50432 Serine hydroxymethyltransferase n=2 Tax=Caenorhabditis elegans
           RepID=GLYC_CAEEL
          Length = 507

 Score =  163 bits (412), Expect = 1e-38
 Identities = 82/161 (50%), Positives = 111/161 (68%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           + ++  Y EQVL N+   A+ + + GY L +GGTDNHL+LV+L+P G++G+R E VL+  
Sbjct: 346 SEDFVQYGEQVLKNAKTLAERMKKHGYALATGGTDNHLLLVDLRPIGVEGARAEHVLDLA 405

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA NKNT PGDVSA+ PGGIR+GTPALTSRGF E+DF KV ++  + V IA K  +EA 
Sbjct: 406 HIACNKNTCPGDVSALRPGGIRLGTPALTSRGFQEQDFEKVGDFIHEGVQIAKKYNAEA- 464

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFE 137
           G  LKDF S  E++   + ++A L   VEEF+ +F   G E
Sbjct: 465 GKTLKDFKSFTETNEPFKKDVADLAKRVEEFSTKFEIPGNE 505

[121][TOP]
>UniRef100_UPI00016DFAAE UPI00016DFAAE related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016DFAAE
          Length = 461

 Score =  162 bits (411), Expect = 2e-38
 Identities = 84/160 (52%), Positives = 108/160 (67%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  +K Y  QV+ N+   A  L++RGY LVSGGTDNHLVLV+L+P+G+DG+R E+VLE V
Sbjct: 301 TPMFKQYISQVMLNAKSMANALLKRGYTLVSGGTDNHLVLVDLRPRGMDGARAERVLELV 360

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+GTPALTSR F E DF KV  + D+ + IAL VK +  
Sbjct: 361 SITANKNTCPGDKSALTPGGMRLGTPALTSRQFKETDFEKVVAFIDEGIQIALNVKKKT- 419

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGF 140
              L  F + +   +   S IA+LR  VE FA+ FP  GF
Sbjct: 420 -GNLASFKAFLLEDAETASRIAELRQRVELFARPFPMPGF 458

[122][TOP]
>UniRef100_B5X423 Serine hydroxymethyltransferase n=1 Tax=Salmo salar
           RepID=B5X423_SALSA
          Length = 503

 Score =  162 bits (411), Expect = 2e-38
 Identities = 84/161 (52%), Positives = 109/161 (67%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ Y  QV+ NS   A+ L+ +GY LVSGGT+NHLVLV+L+PKGIDG+R E+VLE V
Sbjct: 343 TPMFREYIGQVMRNSKAMAEALLSKGYTLVSGGTENHLVLVDLRPKGIDGARAERVLELV 402

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+G PALTSR F E DF +V E+ D+   IAL VK +  
Sbjct: 403 SITANKNTCPGDKSALAPGGLRLGAPALTSRQFKETDFVQVVEFMDEGFKIALDVKKKT- 461

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFE 137
             KL DF + +       + +A+LR  VE FA+ FP  GFE
Sbjct: 462 -GKLADFKNFLLEDPETVARMAELRKRVEAFARPFPMPGFE 501

[123][TOP]
>UniRef100_Q9CWR5 Serine hydroxymethyltransferase n=1 Tax=Mus musculus
           RepID=Q9CWR5_MOUSE
          Length = 478

 Score =  162 bits (411), Expect = 2e-38
 Identities = 82/160 (51%), Positives = 108/160 (67%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T+E+K YQ QVL+N    +  L E GY++V+GG+DNHL+L++L+ KG DG R EKVLEA 
Sbjct: 315 TTEFKIYQLQVLANCRALSDALTELGYKIVTGGSDNHLILMDLRSKGTDGGRAEKVLEAC 374

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-A 263
            IA NKNT PGD SA+ P G+R+GTPALTSRG +EEDF KVA +  + + + L+++S  A
Sbjct: 375 SIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKVAHFIHRGIELTLQIQSHMA 434

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   +     IQS +A LR EVE FA  F   G
Sbjct: 435 TKATLKEFKEKLAGDEKIQSAVATLREEVENFASNFSLPG 474

[124][TOP]
>UniRef100_Q8R0X9 Serine hydroxymethyltransferase n=1 Tax=Mus musculus
           RepID=Q8R0X9_MOUSE
          Length = 478

 Score =  162 bits (411), Expect = 2e-38
 Identities = 82/160 (51%), Positives = 108/160 (67%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T+E+K YQ QVL+N    +  L E GY++V+GG+DNHL+L++L+ KG DG R EKVLEA 
Sbjct: 315 TTEFKIYQLQVLANCRALSDALTELGYKIVTGGSDNHLILMDLRSKGTDGGRAEKVLEAC 374

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-A 263
            IA NKNT PGD SA+ P G+R+GTPALTSRG +EEDF KVA +  + + + L+++S  A
Sbjct: 375 SIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKVAHFIHRGIELTLQIQSHMA 434

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   +     IQS +A LR EVE FA  F   G
Sbjct: 435 TKATLKEFKEKLAGDEKIQSAVATLREEVENFASNFSLPG 474

[125][TOP]
>UniRef100_Q6TXG7 Serine hydroxymethyltransferase n=1 Tax=Rattus norvegicus
           RepID=Q6TXG7_RAT
          Length = 681

 Score =  162 bits (411), Expect = 2e-38
 Identities = 80/160 (50%), Positives = 107/160 (66%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T+E+K YQ QVL+N    +  L E GY++V+GG+DNHL+L++L+PKG DG R EKVLEA 
Sbjct: 518 TTEFKIYQLQVLANCRALSDALTELGYKIVTGGSDNHLILMDLRPKGTDGGRAEKVLEAC 577

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-A 263
            IA NKNT PGD SA+ P G+R+GTPALTSRG +EEDF K+A +  + + + L+++S   
Sbjct: 578 SIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKIAHFIHRGIELTLQIQSHMT 637

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   +      QS +A LR EVE FA  F   G
Sbjct: 638 MRATLKEFKEKLTGDEKFQSAVAALREEVENFASNFSLPG 677

[126][TOP]
>UniRef100_Q4KLG7 Shmt1 protein (Fragment) n=1 Tax=Rattus norvegicus RepID=Q4KLG7_RAT
          Length = 352

 Score =  162 bits (411), Expect = 2e-38
 Identities = 80/160 (50%), Positives = 107/160 (66%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T+E+K YQ QVL+N    +  L E GY++V+GG+DNHL+L++L+PKG DG R EKVLEA 
Sbjct: 189 TTEFKIYQLQVLANCRALSDALTELGYKIVTGGSDNHLILMDLRPKGTDGGRAEKVLEAC 248

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-A 263
            IA NKNT PGD SA+ P G+R+GTPALTSRG +EEDF K+A +  + + + L+++S   
Sbjct: 249 SIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKIAHFIHRGIELTLQIQSHMT 308

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   +      QS +A LR EVE FA  F   G
Sbjct: 309 MRATLKEFKEKLTGDEKFQSAVAALREEVENFASNFSLPG 348

[127][TOP]
>UniRef100_B5Y594 Serine hydroxymethyltransferase n=1 Tax=Phaeodactylum tricornutum
           CCAP 1055/1 RepID=B5Y594_PHATR
          Length = 473

 Score =  162 bits (411), Expect = 2e-38
 Identities = 82/167 (49%), Positives = 113/167 (67%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           ++K Y +QV  N+   A  L   GY + SGGT+NHLVL +LKP+GI GS+ EKV +AV I
Sbjct: 306 DFKVYSQQVKKNAKALADKLTSMGYSMASGGTENHLVLWDLKPQGITGSKFEKVCDAVSI 365

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
             NKN VPGDVSA+ PGG+R+GTPALT+R  VE DF ++ ++  +A+ I L ++ E  G 
Sbjct: 366 TLNKNCVPGDVSAVTPGGVRIGTPALTTRTMVESDFEQIGQFLHEALEITLAIQ-EKSGP 424

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           KLKDF+  +E ++ I++    L+  V +FA  FP  GF+  TMKYKN
Sbjct: 425 KLKDFLPLLEKNADIEA----LKVRVHDFATTFPMPGFDPATMKYKN 467

[128][TOP]
>UniRef100_P50431 Serine hydroxymethyltransferase, cytosolic n=1 Tax=Mus musculus
           RepID=GLYC_MOUSE
          Length = 478

 Score =  162 bits (411), Expect = 2e-38
 Identities = 82/160 (51%), Positives = 108/160 (67%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T+E+K YQ QVL+N    +  L E GY++V+GG+DNHL+L++L+ KG DG R EKVLEA 
Sbjct: 315 TTEFKIYQLQVLANCRALSDALTELGYKIVTGGSDNHLILMDLRSKGTDGGRAEKVLEAC 374

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-A 263
            IA NKNT PGD SA+ P G+R+GTPALTSRG +EEDF KVA +  + + + L+++S  A
Sbjct: 375 SIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKVAHFIHRGIELTLQIQSHMA 434

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   +     IQS +A LR EVE FA  F   G
Sbjct: 435 TKATLKEFKEKLAGDEKIQSAVATLREEVENFASNFSLPG 474

[129][TOP]
>UniRef100_UPI00016E5FAA UPI00016E5FAA related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E5FAA
          Length = 503

 Score =  162 bits (410), Expect = 2e-38
 Identities = 83/157 (52%), Positives = 104/157 (66%)
 Frame = -3

Query: 610 YKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIA 431
           +K Y  QVL N+   A  L+ +GY LVSGGTDNHLVLV+L+P GIDG+R E+VLE   I 
Sbjct: 346 FKDYIAQVLKNAKAMATALISKGYTLVSGGTDNHLVLVDLRPMGIDGARAERVLELASIT 405

Query: 430 SNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTK 251
           +NKNT PGD SA+ PGG+R+G PALTSR F E DF KV E+ D+   I L VK +    K
Sbjct: 406 ANKNTCPGDTSALTPGGLRLGAPALTSRQFKEADFVKVVEFMDEGFKIGLDVKKKT--GK 463

Query: 250 LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGF 140
           L++F + +       + IA LRH VE FA+ FP  GF
Sbjct: 464 LQEFKNVLVQDPETVARIADLRHRVEAFARPFPMPGF 500

[130][TOP]
>UniRef100_UPI00016E5FA9 UPI00016E5FA9 related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E5FA9
          Length = 497

 Score =  162 bits (410), Expect = 2e-38
 Identities = 83/157 (52%), Positives = 104/157 (66%)
 Frame = -3

Query: 610 YKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIA 431
           +K Y  QVL N+   A  L+ +GY LVSGGTDNHLVLV+L+P GIDG+R E+VLE   I 
Sbjct: 340 FKDYIAQVLKNAKAMATALISKGYTLVSGGTDNHLVLVDLRPMGIDGARAERVLELASIT 399

Query: 430 SNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTK 251
           +NKNT PGD SA+ PGG+R+G PALTSR F E DF KV E+ D+   I L VK +    K
Sbjct: 400 ANKNTCPGDTSALTPGGLRLGAPALTSRQFKEADFVKVVEFMDEGFKIGLDVKKKT--GK 457

Query: 250 LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGF 140
           L++F + +       + IA LRH VE FA+ FP  GF
Sbjct: 458 LQEFKNVLVQDPETVARIADLRHRVEAFARPFPMPGF 494

[131][TOP]
>UniRef100_UPI00016E5FA8 UPI00016E5FA8 related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E5FA8
          Length = 501

 Score =  162 bits (410), Expect = 2e-38
 Identities = 83/157 (52%), Positives = 104/157 (66%)
 Frame = -3

Query: 610 YKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIA 431
           +K Y  QVL N+   A  L+ +GY LVSGGTDNHLVLV+L+P GIDG+R E+VLE   I 
Sbjct: 344 FKDYIAQVLKNAKAMATALISKGYTLVSGGTDNHLVLVDLRPMGIDGARAERVLELASIT 403

Query: 430 SNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTK 251
           +NKNT PGD SA+ PGG+R+G PALTSR F E DF KV E+ D+   I L VK +    K
Sbjct: 404 ANKNTCPGDTSALTPGGLRLGAPALTSRQFKEADFVKVVEFMDEGFKIGLDVKKKT--GK 461

Query: 250 LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGF 140
           L++F + +       + IA LRH VE FA+ FP  GF
Sbjct: 462 LQEFKNVLVQDPETVARIADLRHRVEAFARPFPMPGF 498

[132][TOP]
>UniRef100_UPI00016E5FA7 UPI00016E5FA7 related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E5FA7
          Length = 445

 Score =  162 bits (410), Expect = 2e-38
 Identities = 83/157 (52%), Positives = 104/157 (66%)
 Frame = -3

Query: 610 YKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIA 431
           +K Y  QVL N+   A  L+ +GY LVSGGTDNHLVLV+L+P GIDG+R E+VLE   I 
Sbjct: 288 FKDYIAQVLKNAKAMATALISKGYTLVSGGTDNHLVLVDLRPMGIDGARAERVLELASIT 347

Query: 430 SNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTK 251
           +NKNT PGD SA+ PGG+R+G PALTSR F E DF KV E+ D+   I L VK +    K
Sbjct: 348 ANKNTCPGDTSALTPGGLRLGAPALTSRQFKEADFVKVVEFMDEGFKIGLDVKKKT--GK 405

Query: 250 LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGF 140
           L++F + +       + IA LRH VE FA+ FP  GF
Sbjct: 406 LQEFKNVLVQDPETVARIADLRHRVEAFARPFPMPGF 442

[133][TOP]
>UniRef100_UPI00016E5FA6 UPI00016E5FA6 related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E5FA6
          Length = 500

 Score =  162 bits (410), Expect = 2e-38
 Identities = 83/157 (52%), Positives = 104/157 (66%)
 Frame = -3

Query: 610 YKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIA 431
           +K Y  QVL N+   A  L+ +GY LVSGGTDNHLVLV+L+P GIDG+R E+VLE   I 
Sbjct: 343 FKDYIAQVLKNAKAMATALISKGYTLVSGGTDNHLVLVDLRPMGIDGARAERVLELASIT 402

Query: 430 SNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTK 251
           +NKNT PGD SA+ PGG+R+G PALTSR F E DF KV E+ D+   I L VK +    K
Sbjct: 403 ANKNTCPGDTSALTPGGLRLGAPALTSRQFKEADFVKVVEFMDEGFKIGLDVKKKT--GK 460

Query: 250 LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGF 140
           L++F + +       + IA LRH VE FA+ FP  GF
Sbjct: 461 LQEFKNVLVQDPETVARIADLRHRVEAFARPFPMPGF 497

[134][TOP]
>UniRef100_UPI00016E087B UPI00016E087B related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E087B
          Length = 506

 Score =  162 bits (410), Expect = 2e-38
 Identities = 84/160 (52%), Positives = 108/160 (67%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  +K Y  QV+ N+   A  L++RGY LVSGGTDNHLVLV+L+P+G+DG+R E+VLE V
Sbjct: 346 TPMFKQYISQVMLNAKSMANALLKRGYTLVSGGTDNHLVLVDLRPRGMDGARAERVLELV 405

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+GTPALTSR F E DF KV  + D+ + IAL VK +  
Sbjct: 406 SITANKNTCPGDKSALTPGGMRLGTPALTSRQFKETDFEKVVAFIDEGIQIALDVKKKT- 464

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGF 140
              L  F + +   +   S IA+LR  VE FA+ FP  GF
Sbjct: 465 -GNLASFKAFLLEDAETASRIAELRQRVELFARPFPMPGF 503

[135][TOP]
>UniRef100_UPI00016E087A UPI00016E087A related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E087A
          Length = 435

 Score =  162 bits (410), Expect = 2e-38
 Identities = 84/160 (52%), Positives = 108/160 (67%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  +K Y  QV+ N+   A  L++RGY LVSGGTDNHLVLV+L+P+G+DG+R E+VLE V
Sbjct: 275 TPMFKQYISQVMLNAKSMANALLKRGYTLVSGGTDNHLVLVDLRPRGMDGARAERVLELV 334

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+GTPALTSR F E DF KV  + D+ + IAL VK +  
Sbjct: 335 SITANKNTCPGDKSALTPGGMRLGTPALTSRQFKETDFEKVVAFIDEGIQIALDVKKKT- 393

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGF 140
              L  F + +   +   S IA+LR  VE FA+ FP  GF
Sbjct: 394 -GNLASFKAFLLEDAETASRIAELRQRVELFARPFPMPGF 432

[136][TOP]
>UniRef100_UPI00016E0879 UPI00016E0879 related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E0879
          Length = 491

 Score =  162 bits (410), Expect = 2e-38
 Identities = 84/160 (52%), Positives = 108/160 (67%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  +K Y  QV+ N+   A  L++RGY LVSGGTDNHLVLV+L+P+G+DG+R E+VLE V
Sbjct: 331 TPMFKQYISQVMLNAKSMANALLKRGYTLVSGGTDNHLVLVDLRPRGMDGARAERVLELV 390

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+GTPALTSR F E DF KV  + D+ + IAL VK +  
Sbjct: 391 SITANKNTCPGDKSALTPGGMRLGTPALTSRQFKETDFEKVVAFIDEGIQIALDVKKKT- 449

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGF 140
              L  F + +   +   S IA+LR  VE FA+ FP  GF
Sbjct: 450 -GNLASFKAFLLEDAETASRIAELRQRVELFARPFPMPGF 488

[137][TOP]
>UniRef100_UPI00016E0878 UPI00016E0878 related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E0878
          Length = 499

 Score =  162 bits (410), Expect = 2e-38
 Identities = 84/160 (52%), Positives = 108/160 (67%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  +K Y  QV+ N+   A  L++RGY LVSGGTDNHLVLV+L+P+G+DG+R E+VLE V
Sbjct: 339 TPMFKQYISQVMLNAKSMANALLKRGYTLVSGGTDNHLVLVDLRPRGMDGARAERVLELV 398

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+GTPALTSR F E DF KV  + D+ + IAL VK +  
Sbjct: 399 SITANKNTCPGDKSALTPGGMRLGTPALTSRQFKETDFEKVVAFIDEGIQIALDVKKKT- 457

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGF 140
              L  F + +   +   S IA+LR  VE FA+ FP  GF
Sbjct: 458 -GNLASFKAFLLEDAETASRIAELRQRVELFARPFPMPGF 496

[138][TOP]
>UniRef100_UPI00006608D0 UPI00006608D0 related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00006608D0
          Length = 499

 Score =  162 bits (410), Expect = 2e-38
 Identities = 84/160 (52%), Positives = 108/160 (67%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  +K Y  QV+ N+   A  L++RGY LVSGGTDNHLVLV+L+P+G+DG+R E+VLE V
Sbjct: 339 TPMFKQYISQVMLNAKSMANALLKRGYTLVSGGTDNHLVLVDLRPRGMDGARAERVLELV 398

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNT PGD SA+ PGG+R+GTPALTSR F E DF KV  + D+ + IAL VK +  
Sbjct: 399 SITANKNTCPGDKSALTPGGMRLGTPALTSRQFKETDFEKVVAFIDEGIQIALDVKKKT- 457

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGF 140
              L  F + +   +   S IA+LR  VE FA+ FP  GF
Sbjct: 458 -GNLASFKAFLLEDAETASRIAELRQRVELFARPFPMPGF 496

[139][TOP]
>UniRef100_A4HW78 Serine hydroxymethyltransferase n=1 Tax=Leishmania infantum
           RepID=A4HW78_LEIIN
          Length = 465

 Score =  162 bits (410), Expect = 2e-38
 Identities = 83/167 (49%), Positives = 116/167 (69%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+KAY  QV SN+   A  L  +G+  VSGGTDNHL+L N++  G+ GS+VEK+L+AV I
Sbjct: 297 EWKAYAMQVQSNARALAAALSSKGHVFVSGGTDNHLLLWNVRVHGLTGSKVEKLLDAVSI 356

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           + NKNT+PGD SAM PGGIR+GT ALTSRG VE D + VAE+ D+A+ +A ++++     
Sbjct: 357 SVNKNTIPGDKSAMTPGGIRVGTLALTSRGMVEADMSTVAEFLDRAIVLAKQIQAAMNAM 416

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           KL DFV+A+++     + +A LR +VE FA  F    F+ E +KYK+
Sbjct: 417 KLSDFVAALQT----HAGVAALRKDVEAFATTFAMPSFDVERIKYKD 459

[140][TOP]
>UniRef100_C9SQ14 Serine hydroxymethyltransferase n=1 Tax=Verticillium albo-atrum
           VaMs.102 RepID=C9SQ14_9PEZI
          Length = 536

 Score =  162 bits (410), Expect = 2e-38
 Identities = 90/171 (52%), Positives = 117/171 (68%), Gaps = 15/171 (8%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMER------GYELVSGGTDNHLVLVNLKPKGIDGSRVE 458
           T E++AYQ QVLSN+   A  L E       GY+LV GGT+NHLVLV+LKP+GIDGSRVE
Sbjct: 358 TPEFRAYQTQVLSNAKALAHRLGESKEKGGLGYKLVGGGTENHLVLVDLKPQGIDGSRVE 417

Query: 457 KVLEAVHIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALK 278
           +VLE V +ASNKNTVPGD SA+VPGG+R+GTPA+T+RGF EEDF +VA+  D+AVTIA++
Sbjct: 418 RVLELVGVASNKNTVPGDRSALVPGGLRIGTPAMTTRGFSEEDFGRVADIIDRAVTIAVR 477

Query: 277 VKSEA------QGTK---LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 152
           +   A      +G K   L+    A   +     EI +LR EV ++   +P
Sbjct: 478 IDKAAKKAAAERGEKKPGLQRIFMAHLGNGDSDPEIVQLRSEVSDWVGTYP 528

[141][TOP]
>UniRef100_A3LY87 Serine hydroxymethyltransferase n=1 Tax=Pichia stipitis
           RepID=A3LY87_PICST
          Length = 492

 Score =  162 bits (410), Expect = 2e-38
 Identities = 78/157 (49%), Positives = 114/157 (72%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           EYK YQ  V++N++ FA  L+ RG++LVS GTD HL+LV+L+ K IDG+RVE VLE  +I
Sbjct: 334 EYKEYQRDVVANASSFANALVSRGFKLVSDGTDTHLILVDLRSKNIDGARVEAVLERANI 393

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           A+NKNTVPGD SA+ P G+R+GTPA+T+RGF  E+F KVA+  +KAV I+L +K++ QG+
Sbjct: 394 AANKNTVPGDKSALFPSGLRVGTPAMTTRGFGPEEFDKVAKLIEKAVEISLALKAQEQGS 453

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
             K+ +++ +  +   +E+  L  EV ++A  FP  G
Sbjct: 454 VPKELLASFKKLADSSAEVKALAKEVSDWASTFPVPG 490

[142][TOP]
>UniRef100_Q4QFK2 Serine hydroxymethyltransferase n=1 Tax=Leishmania major
           RepID=Q4QFK2_LEIMA
          Length = 465

 Score =  162 bits (409), Expect = 3e-38
 Identities = 83/169 (49%), Positives = 115/169 (68%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           + E+KAY  QV SN+   A  L  +G+  VSGGTDNHL+L N++  G+ GS+VEK+L+AV
Sbjct: 295 SQEWKAYARQVQSNARALAAALSSKGHVFVSGGTDNHLLLWNVRVHGLTGSKVEKLLDAV 354

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I+ NKNT+PGD SAM PGGIR+GT ALTSRG VE D + VAE+ D+A+ +A ++++   
Sbjct: 355 SISVNKNTIPGDKSAMTPGGIRVGTLALTSRGMVEADMSTVAEFLDRAIVLAKQIQAAMN 414

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
             KL DFV A+++     +  A LR +VE FA  F    F+ E +KYK+
Sbjct: 415 AVKLSDFVEALQT----HAGAAALRKDVEAFATTFAMPSFDVERIKYKD 459

[143][TOP]
>UniRef100_Q23PT8 Serine hydroxymethyltransferase n=1 Tax=Tetrahymena thermophila
           SB210 RepID=Q23PT8_TETTH
          Length = 487

 Score =  162 bits (409), Expect = 3e-38
 Identities = 79/155 (50%), Positives = 116/155 (74%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T +YK YQ QVL NS   A++L++R Y LVSGGTDNHLVL++L+ K +DG+R+E +LE V
Sbjct: 327 TPQYKEYQTQVLQNSKAMAESLLKRNYTLVSGGTDNHLVLLDLRSKNLDGARMETLLELV 386

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           +I  NKNTVPGD SA++P G+R+GTPALT+RG VE+D  +V E+ D+A  +  ++ S+  
Sbjct: 387 NIYVNKNTVPGDKSALIPSGLRLGTPALTTRGLVEKDIDQVVEFIDRATHLVPQI-SKQS 445

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQF 155
           G+K+ +F S ++++S    E+  LR+EV +F+KQF
Sbjct: 446 GSKVAEFKSWIQANSESVPELVSLRNEVIQFSKQF 480

[144][TOP]
>UniRef100_Q6FQ44 Serine hydroxymethyltransferase, mitochondrial n=1 Tax=Candida
           glabrata RepID=GLYM_CANGA
          Length = 485

 Score =  162 bits (409), Expect = 3e-38
 Identities = 83/162 (51%), Positives = 115/162 (70%), Gaps = 3/162 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+  YQ+QV+SN+  F   L++RG+ELVSGGTDNHL+L+NL   GIDG+R+E +LE +
Sbjct: 323 TPEFVEYQKQVVSNAKAFGDELLKRGFELVSGGTDNHLLLLNLSNMGIDGARLEAILEKI 382

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           +IA+NKNT+PGD SA+ P G+R+GTPA+T+RGF E+DF KVAEY D AV +++ +KS+ +
Sbjct: 383 NIAANKNTIPGDKSALFPSGLRVGTPAMTTRGFQEQDFKKVAEYIDNAVKLSIALKSQ-E 441

Query: 259 GTKLKDFVSAMESSSTI--QSE-IAKLRHEVEEFAKQFPTIG 143
               KD  S + S   +  QSE + KL  EV  +   FP  G
Sbjct: 442 SADAKDVRSKLNSFKQLCDQSEPVQKLAEEVSSWVGTFPVPG 483

[145][TOP]
>UniRef100_UPI000194D5CE PREDICTED: similar to serine hydroxymethyltransferase 1 (soluble)
           n=1 Tax=Taeniopygia guttata RepID=UPI000194D5CE
          Length = 482

 Score =  161 bits (408), Expect = 4e-38
 Identities = 82/160 (51%), Positives = 110/160 (68%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+KAYQ+QV++N    +  LME GY++V+GG+DNHL+LV+L+ KG DG R E+VLE  
Sbjct: 320 TPEFKAYQQQVVANCKALSSALMEMGYDIVTGGSDNHLILVDLRSKGTDGGRAERVLELC 379

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKV-KSEA 263
            IA NKNT PGDVSA+ P G+R GTPALTSRGF ++DF KVA+Y  + + +AL+V K  +
Sbjct: 380 SIACNKNTCPGDVSALRPSGLRFGTPALTSRGFRQDDFRKVAQYIHRGIELALRVQKDMS 439

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   +E     + E+  L+ EVE FA  FP  G
Sbjct: 440 PKATLKEFKDKLEDPK-YRGELKALKEEVEAFAGTFPLPG 478

[146][TOP]
>UniRef100_B9HDQ7 Serine hydroxymethyltransferase n=1 Tax=Populus trichocarpa
           RepID=B9HDQ7_POPTR
          Length = 529

 Score =  161 bits (408), Expect = 4e-38
 Identities = 77/158 (48%), Positives = 112/158 (70%), Gaps = 1/158 (0%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+KAYQ+QV+ NS   A  ++E GY+LVSGG+DNHL+LV+L+P G+DG+RVEK+L+   I
Sbjct: 371 EFKAYQKQVICNSRALANRMVELGYKLVSGGSDNHLILVDLRPLGLDGARVEKILDMASI 430

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
             NKN+VPGD SA+VPGGIR+G+PA+T+RGF E +F   A+   + V I+L+ K    G+
Sbjct: 431 TLNKNSVPGDKSALVPGGIRIGSPAMTTRGFTETEFVATADLIHEGVQISLEAKKSVSGS 490

Query: 253 KLKDFVSAMESSS-TIQSEIAKLRHEVEEFAKQFPTIG 143
           KL+DF+  ++S    +  +++ L+  VE    QFP  G
Sbjct: 491 KLQDFLKFVKSPDFPLTDKVSDLQRRVEALTTQFPIPG 528

[147][TOP]
>UniRef100_C5KPS8 Serine hydroxymethyltransferase n=1 Tax=Perkinsus marinus ATCC
           50983 RepID=C5KPS8_9ALVE
          Length = 607

 Score =  161 bits (407), Expect = 5e-38
 Identities = 81/159 (50%), Positives = 118/159 (74%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EY+ YQEQV+ NS   A+ LM+ GY+LVSGGTDNHLVL++L+ KGI+G++ EK+ + V
Sbjct: 451 TEEYRHYQEQVVKNSKALAEELMKLGYDLVSGGTDNHLVLLDLRSKGINGNKTEKLCDHV 510

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I+ NKNTVPGD SA+ P G+R+G PA+T+RG  E+DF K+A++  + V I L+V+ ++ 
Sbjct: 511 AISLNKNTVPGDKSAITPSGLRIGAPAMTTRGANEDDFRKIAQFIHRVVEIGLQVQKQS- 569

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
           G KLKDF++ +++S     E+A+LR EV  F++ F  IG
Sbjct: 570 GPKLKDFLAILDNSP--PPELAQLRDEVMTFSRGFVPIG 606

[148][TOP]
>UniRef100_Q60V73 Serine hydroxymethyltransferase n=2 Tax=Caenorhabditis briggsae
           RepID=GLYC_CAEBR
          Length = 511

 Score =  160 bits (406), Expect = 6e-38
 Identities = 79/159 (49%), Positives = 110/159 (69%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           + ++  Y EQ+L N+   A+ L + GY L +GGTDNHL+LV+L+P G++G+R E +L+  
Sbjct: 350 SEDFVQYGEQILKNAKTLAERLKKHGYSLATGGTDNHLLLVDLRPIGVEGARAEHILDLA 409

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HIA NKNT PGDVSA+ PGGIR+GTPALTSRGF E+DF KV ++  + V IA K  +EA 
Sbjct: 410 HIACNKNTCPGDVSALRPGGIRLGTPALTSRGFKEQDFEKVGDFIHEGVQIAKKYNAEA- 468

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
           G  LKDF +   ++   + E+A+L   VEEF+ +F   G
Sbjct: 469 GKTLKDFKAFTATNEQFKQEVAELAKRVEEFSGKFEIPG 507

[149][TOP]
>UniRef100_A7SS63 Serine hydroxymethyltransferase n=1 Tax=Nematostella vectensis
           RepID=A7SS63_NEMVE
          Length = 470

 Score =  160 bits (405), Expect = 8e-38
 Identities = 78/159 (49%), Positives = 111/159 (69%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+KAY +Q+L N    A+  MERGY+LV+ GTDNHLVL++L+PKGI G++ E++LE +
Sbjct: 310 TPEFKAYGQQILGNCKAMAEVFMERGYKLVTDGTDNHLVLMDLRPKGIGGAQAERILEEI 369

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I  NKNT PGD SA+ PGG+R+G PALTSR F   DF +VA++ D+ + + L+++ E  
Sbjct: 370 SITVNKNTCPGDKSALKPGGLRIGAPALTSRKFKVHDFKQVADFIDRGIKLGLEIQ-EVA 428

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
           GT  K F+ A+ SS     ++  LR EVE+F+ +FP  G
Sbjct: 429 GTDFKKFIEAL-SSEKFSEKVESLRKEVEKFSGKFPMPG 466

[150][TOP]
>UniRef100_P35623 Serine hydroxymethyltransferase, cytosolic n=1 Tax=Ovis aries
           RepID=GLYC_SHEEP
          Length = 484

 Score =  160 bits (405), Expect = 8e-38
 Identities = 82/161 (50%), Positives = 110/161 (68%), Gaps = 2/161 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E++AYQ QV++N    A+ LM  GY +V+GG+DNHL+LV+L+ KG DG R EKVLEA 
Sbjct: 321 TPEFRAYQRQVVANCRALAEALMGLGYRVVTGGSDNHLILVDLRSKGTDGGRAEKVLEAC 380

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            IA NKNT PGD SA+ P G+R+GTPALTSRG +EEDF KVA +  + + + L+++ +A 
Sbjct: 381 SIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFRKVAHFIHRGIELTLQIQ-DAV 439

Query: 259 GTK--LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
           G K  LK+F+  +  +   Q  +  LR EVE FA  FP  G
Sbjct: 440 GVKATLKEFMEKLAGAEEHQRAVTALRAEVESFATLFPLPG 480

[151][TOP]
>UniRef100_UPI00018635C2 hypothetical protein BRAFLDRAFT_223174 n=1 Tax=Branchiostoma
           floridae RepID=UPI00018635C2
          Length = 471

 Score =  160 bits (404), Expect = 1e-37
 Identities = 80/159 (50%), Positives = 112/159 (70%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+K Y +QV+ N     + +M++GY +V+ G+DNHL+L++L+ KGI+GS+ EK+LE V I
Sbjct: 313 EFKTYIQQVIKNCQAMCKMMMDKGYHVVTDGSDNHLLLIDLRSKGINGSKTEKILEEVSI 372

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           A NKNT PGD SA+ P G+R GTPALTSRGFVE+DF KV ++ D+A+ +A+++++   G 
Sbjct: 373 ACNKNTCPGDKSALNPSGLRFGTPALTSRGFVEKDFEKVTDFIDRAILLAVEIQT-VSGK 431

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFE 137
            LKDF + M       S+IA LR EVE FA  FP  G E
Sbjct: 432 MLKDFKAKM-VEEPFSSKIAALRAEVEAFAIAFPIPGLE 469

[152][TOP]
>UniRef100_UPI0000162B6C SHM3 (SERINE HYDROXYMETHYLTRANSFERASE 3); catalytic/ glycine
           hydroxymethyltransferase/ pyridoxal phosphate binding
           n=1 Tax=Arabidopsis thaliana RepID=UPI0000162B6C
          Length = 529

 Score =  160 bits (404), Expect = 1e-37
 Identities = 78/158 (49%), Positives = 112/158 (70%), Gaps = 1/158 (0%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+KAYQ++V+SN    A  L+E G++LVSGG+DNHLVLV+L+P G+DG+RVEK+L+   I
Sbjct: 371 EFKAYQKRVVSNCRALANRLVELGFKLVSGGSDNHLVLVDLRPMGMDGARVEKILDMASI 430

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
             NKN+VPGD SA+VPGGIR+G+PA+T+RG  E+DF  VA++  + V I ++ K  A G+
Sbjct: 431 TLNKNSVPGDKSALVPGGIRIGSPAMTTRGLSEKDFVVVADFIKEGVEITMEAKKAAPGS 490

Query: 253 KLKDFVSAMESSS-TIQSEIAKLRHEVEEFAKQFPTIG 143
           KL+DF   + S    ++  +  L+  VE F  +FP  G
Sbjct: 491 KLQDFNKFVTSPEFPLKERVKSLKERVETFTSRFPIPG 528

[153][TOP]
>UniRef100_UPI00017B2450 UPI00017B2450 related cluster n=1 Tax=Tetraodon nigroviridis
           RepID=UPI00017B2450
          Length = 502

 Score =  160 bits (404), Expect = 1e-37
 Identities = 82/157 (52%), Positives = 104/157 (66%)
 Frame = -3

Query: 610 YKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIA 431
           +K Y  QVL N+   A  L+ +GY LVSGGTDNHLVLV+L+P GIDG+R E+VLE   I 
Sbjct: 345 FKDYIAQVLKNAKAMAAALISKGYTLVSGGTDNHLVLVDLRPMGIDGARAERVLELASIT 404

Query: 430 SNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTK 251
           +NKNT PGD SA+ PGG+R+G PALTSR F E DF +V E+ D+   I L VK +    K
Sbjct: 405 ANKNTCPGDTSALTPGGLRLGAPALTSRQFKEADFVQVVEFMDEGFKIGLDVKKKT--GK 462

Query: 250 LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGF 140
           L++F + +       + IA LRH VE FA+ FP  GF
Sbjct: 463 LQEFKNFLVQDPETVARIADLRHRVEAFARPFPMPGF 499

[154][TOP]
>UniRef100_Q4SS81 Serine hydroxymethyltransferase (Fragment) n=1 Tax=Tetraodon
           nigroviridis RepID=Q4SS81_TETNG
          Length = 501

 Score =  160 bits (404), Expect = 1e-37
 Identities = 82/157 (52%), Positives = 104/157 (66%)
 Frame = -3

Query: 610 YKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIA 431
           +K Y  QVL N+   A  L+ +GY LVSGGTDNHLVLV+L+P GIDG+R E+VLE   I 
Sbjct: 344 FKDYIAQVLKNAKAMAAALISKGYTLVSGGTDNHLVLVDLRPMGIDGARAERVLELASIT 403

Query: 430 SNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTK 251
           +NKNT PGD SA+ PGG+R+G PALTSR F E DF +V E+ D+   I L VK +    K
Sbjct: 404 ANKNTCPGDTSALTPGGLRLGAPALTSRQFKEADFVQVVEFMDEGFKIGLDVKKKT--GK 461

Query: 250 LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGF 140
           L++F + +       + IA LRH VE FA+ FP  GF
Sbjct: 462 LQEFKNFLVQDPETVARIADLRHRVEAFARPFPMPGF 498

[155][TOP]
>UniRef100_Q9SUU0 Serine hydroxymethyltransferase n=1 Tax=Arabidopsis thaliana
           RepID=Q9SUU0_ARATH
          Length = 462

 Score =  160 bits (404), Expect = 1e-37
 Identities = 78/158 (49%), Positives = 112/158 (70%), Gaps = 1/158 (0%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+KAYQ++V+SN    A  L+E G++LVSGG+DNHLVLV+L+P G+DG+RVEK+L+   I
Sbjct: 304 EFKAYQKRVVSNCRALANRLVELGFKLVSGGSDNHLVLVDLRPMGMDGARVEKILDMASI 363

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
             NKN+VPGD SA+VPGGIR+G+PA+T+RG  E+DF  VA++  + V I ++ K  A G+
Sbjct: 364 TLNKNSVPGDKSALVPGGIRIGSPAMTTRGLSEKDFVVVADFIKEGVEITMEAKKAAPGS 423

Query: 253 KLKDFVSAMESSS-TIQSEIAKLRHEVEEFAKQFPTIG 143
           KL+DF   + S    ++  +  L+  VE F  +FP  G
Sbjct: 424 KLQDFNKFVTSPEFPLKERVKSLKERVETFTSRFPIPG 461

[156][TOP]
>UniRef100_C3XSQ5 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3XSQ5_BRAFL
          Length = 406

 Score =  160 bits (404), Expect = 1e-37
 Identities = 80/159 (50%), Positives = 112/159 (70%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+K Y +QV+ N     + +M++GY +V+ G+DNHL+L++L+ KGI+GS+ EK+LE V I
Sbjct: 248 EFKTYIQQVIKNCQAMCKMMMDKGYHVVTDGSDNHLLLIDLRSKGINGSKTEKILEEVSI 307

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           A NKNT PGD SA+ P G+R GTPALTSRGFVE+DF KV ++ D+A+ +A+++++   G 
Sbjct: 308 ACNKNTCPGDKSALNPSGLRFGTPALTSRGFVEKDFEKVTDFIDRAILLAVEIQT-VSGK 366

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFE 137
            LKDF + M       S+IA LR EVE FA  FP  G E
Sbjct: 367 MLKDFKAKM-VEEPFSSKIAALRAEVEAFAIAFPIPGLE 404

[157][TOP]
>UniRef100_C5E343 Serine hydroxymethyltransferase n=1 Tax=Lachancea thermotolerans
           CBS 6340 RepID=C5E343_LACTC
          Length = 493

 Score =  160 bits (404), Expect = 1e-37
 Identities = 79/162 (48%), Positives = 118/162 (72%), Gaps = 3/162 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ  V++N++ F + L++RG++LVSGGTD HLVL++L   GIDG+R+E +LE +
Sbjct: 331 TPEFKEYQTAVVANASVFGEELVKRGFQLVSGGTDTHLVLIDLSNIGIDGARLETILEKI 390

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           +IA+NKNT+PGD SA+ P G+R+GTPA+T+RGF  EDFAKVAEY DKA  +A+ +KS+ +
Sbjct: 391 NIAANKNTIPGDKSALFPSGLRVGTPAMTTRGFGPEDFAKVAEYIDKAAKLAIGLKSQ-E 449

Query: 259 GTKLKDFVSAMESSSTI---QSEIAKLRHEVEEFAKQFPTIG 143
            ++ KD  S + +   +     E+A L ++V E+  +FP  G
Sbjct: 450 SSEAKDARSKLANFKQLCAESDEVAALANKVSEWVGEFPVPG 491

[158][TOP]
>UniRef100_B9WKJ4 Serine hydroxymethyltransferase n=1 Tax=Candida dubliniensis CD36
           RepID=B9WKJ4_CANDC
          Length = 493

 Score =  160 bits (404), Expect = 1e-37
 Identities = 75/157 (47%), Positives = 116/157 (73%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           EY  YQ++V+SN+  FA  L+ +G++LVS GTD HL+LV+L+ + IDG+RVE VLE  +I
Sbjct: 335 EYVKYQQEVVSNAKHFADALVSKGFKLVSDGTDTHLILVDLRSRNIDGARVEAVLERANI 394

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           A+NKNTVPGDVSA+ P G+R+GTPA+T+RGF  E+F KVAE+ D+AV IA+++K++ QG 
Sbjct: 395 AANKNTVPGDVSALFPSGLRVGTPAMTTRGFGPEEFDKVAEFIDQAVNIAIELKAQEQGK 454

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
             K+ +++ +  +   +++ +L  EV  +  ++P  G
Sbjct: 455 VPKELLASFKQLADESNKVKQLDKEVVSWVSKYPVPG 491

[159][TOP]
>UniRef100_Q5E9P9 Serine hydroxymethyltransferase, cytosolic n=1 Tax=Bos taurus
           RepID=GLYC_BOVIN
          Length = 484

 Score =  160 bits (404), Expect = 1e-37
 Identities = 82/161 (50%), Positives = 110/161 (68%), Gaps = 2/161 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E++AYQ QV++N    A+ LM  GY +V+GG+DNHL+LV+L+ KG DG R EKVLEA 
Sbjct: 321 TPEFRAYQRQVVANCRALAEALMGLGYRVVTGGSDNHLILVDLRSKGTDGGRAEKVLEAC 380

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            IA NKNT PGD SA+ P G+R+GTPALTSRG +EEDF KVA +  + + + L+++ +A 
Sbjct: 381 SIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKVAHFIHRGIELTLQIQ-DAV 439

Query: 259 GTK--LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
           G K  LK+F+  +  +      +A LR EVE FA  FP  G
Sbjct: 440 GVKATLKEFMEKLAGAEEHHRAVAALRAEVESFATLFPLPG 480

[160][TOP]
>UniRef100_UPI0001A2B9EF Serine hydroxymethyltransferase, mitochondrial precursor (EC
           2.1.2.1) (Serine methylase) (Glycine
           hydroxymethyltransferase) (SHMT). n=1 Tax=Danio rerio
           RepID=UPI0001A2B9EF
          Length = 487

 Score =  159 bits (403), Expect = 1e-37
 Identities = 83/157 (52%), Positives = 106/157 (67%)
 Frame = -3

Query: 610 YKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIA 431
           ++ Y  QVL NS   A  L+++GY LVSGGTDNHLVLV+L+P+G+DG+R E+VLE V I 
Sbjct: 330 FREYIAQVLKNSKAMAAALLDKGYTLVSGGTDNHLVLVDLRPQGMDGARAERVLELVSIT 389

Query: 430 SNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTK 251
           +NKNT PGD SA+ PGG+R+GTPALTSR   E DF KV E+  + + I   VK + +  K
Sbjct: 390 ANKNTCPGDKSALTPGGLRLGTPALTSRQLKECDFQKVVEFIHQGIQIGQDVKKKTK--K 447

Query: 250 LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGF 140
           L DF S +   +   S IA LR  VE FA+ FP  GF
Sbjct: 448 LSDFKSFLLEDAETVSRIADLRSRVEAFARPFPMPGF 484

[161][TOP]
>UniRef100_Q8AVC0 Serine hydroxymethyltransferase n=1 Tax=Xenopus laevis
           RepID=Q8AVC0_XENLA
          Length = 485

 Score =  159 bits (403), Expect = 1e-37
 Identities = 83/158 (52%), Positives = 106/158 (67%), Gaps = 1/158 (0%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+K YQ+QV+SN    +  + E GY +V+GG+DNHL+LVNL+ K  DG R EKVLEA  I
Sbjct: 324 EFKLYQKQVVSNCKALSLAIEELGYHVVTGGSDNHLILVNLRDKKTDGGRAEKVLEACSI 383

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKV-KSEAQG 257
           A NKNT PGD SA+ P G+R+GTPALTSRGF EEDF KVA++  + + + L++ KS   G
Sbjct: 384 ACNKNTCPGDKSALRPSGLRLGTPALTSRGFNEEDFKKVAQFIHRGIELTLEIQKSMNPG 443

Query: 256 TKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
             LKDF   + S      +I  LR EVE+FA  FP  G
Sbjct: 444 ATLKDFKEKLASQDVHTPKILALRAEVEKFAGTFPIPG 481

[162][TOP]
>UniRef100_A9LDD9 Mitochondrial serine hydroxymethyltransferase n=1 Tax=Danio rerio
           RepID=A9LDD9_DANRE
          Length = 492

 Score =  159 bits (403), Expect = 1e-37
 Identities = 83/157 (52%), Positives = 106/157 (67%)
 Frame = -3

Query: 610 YKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIA 431
           ++ Y  QVL NS   A  L+++GY LVSGGTDNHLVLV+L+P+G+DG+R E+VLE V I 
Sbjct: 335 FREYIAQVLKNSKAMAAALLDKGYTLVSGGTDNHLVLVDLRPQGMDGARAERVLELVSIT 394

Query: 430 SNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTK 251
           +NKNT PGD SA+ PGG+R+GTPALTSR   E DF KV E+  + + I   VK + +  K
Sbjct: 395 ANKNTCPGDKSALTPGGLRLGTPALTSRQLKECDFQKVVEFIHQGIQIGQDVKKKTK--K 452

Query: 250 LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGF 140
           L DF S +   +   S IA LR  VE FA+ FP  GF
Sbjct: 453 LSDFKSFLLEDAETVSRIADLRSRVEAFARPFPMPGF 489

[163][TOP]
>UniRef100_Q59PP7 Serine hydroxymethyltransferase n=1 Tax=Candida albicans
           RepID=Q59PP7_CANAL
          Length = 493

 Score =  159 bits (403), Expect = 1e-37
 Identities = 75/157 (47%), Positives = 115/157 (73%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           EY  YQ++V+SN+  FA  L+ +G++LVS GTD HL+LV+L+ + IDG+RVE VLE  +I
Sbjct: 335 EYVKYQQEVVSNAKHFADALVSKGFKLVSDGTDTHLILVDLRSRNIDGARVEAVLERANI 394

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           A+NKNTVPGDVSA+ P G+R+GTPA+T+RGF  E+F KVAE+ D+AV IA+++K++ QG 
Sbjct: 395 ATNKNTVPGDVSALFPSGLRVGTPAMTTRGFGPEEFDKVAEFIDQAVNIAIELKAQEQGK 454

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
             K+ +++ +  +    ++ +L  EV  +  ++P  G
Sbjct: 455 VPKELLASFKKLADESDKVKQLDKEVVSWVSKYPVPG 491

[164][TOP]
>UniRef100_Q59PM9 Serine hydroxymethyltransferase n=1 Tax=Candida albicans
           RepID=Q59PM9_CANAL
          Length = 493

 Score =  159 bits (403), Expect = 1e-37
 Identities = 75/157 (47%), Positives = 115/157 (73%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           EY  YQ++V+SN+  FA  L+ +G++LVS GTD HL+LV+L+ + IDG+RVE VLE  +I
Sbjct: 335 EYVKYQQEVVSNAKHFADALVSKGFKLVSDGTDTHLILVDLRSRNIDGARVEAVLERANI 394

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           A+NKNTVPGDVSA+ P G+R+GTPA+T+RGF  E+F KVAE+ D+AV IA+++K++ QG 
Sbjct: 395 AANKNTVPGDVSALFPSGLRVGTPAMTTRGFGPEEFDKVAEFIDQAVNIAIELKAQEQGK 454

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
             K+ +++ +  +    ++ +L  EV  +  ++P  G
Sbjct: 455 VPKELLASFKKLADESDKVKQLDKEVVSWVSKYPVPG 491

[165][TOP]
>UniRef100_C4YSX1 Serine hydroxymethyltransferase n=1 Tax=Candida albicans
           RepID=C4YSX1_CANAL
          Length = 493

 Score =  159 bits (403), Expect = 1e-37
 Identities = 75/157 (47%), Positives = 115/157 (73%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           EY  YQ++V+SN+  FA  L+ +G++LVS GTD HL+LV+L+ + IDG+RVE VLE  +I
Sbjct: 335 EYVKYQQEVVSNAKHFADALVSKGFKLVSDGTDTHLILVDLRSRNIDGARVEAVLERANI 394

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           A+NKNTVPGDVSA+ P G+R+GTPA+T+RGF  E+F KVAE+ D+AV IA+++K++ QG 
Sbjct: 395 ATNKNTVPGDVSALFPSGLRVGTPAMTTRGFGPEEFDKVAEFIDQAVNIAIELKAQEQGK 454

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
             K+ +++ +  +    ++ +L  EV  +  ++P  G
Sbjct: 455 VPKELLASFKKLADESDKVKQLDKEVVSWVSKYPVPG 491

[166][TOP]
>UniRef100_O13425 Serine hydroxymethyltransferase, mitochondrial n=1 Tax=Candida
           albicans RepID=GLYM_CANAL
          Length = 493

 Score =  159 bits (403), Expect = 1e-37
 Identities = 75/157 (47%), Positives = 115/157 (73%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           EY  YQ++V+SN+  FA  L+ +G++LVS GTD HL+LV+L+ + IDG+RVE VLE  +I
Sbjct: 335 EYVKYQQEVVSNAKHFADALVSKGFKLVSDGTDTHLILVDLRSRNIDGARVEAVLERANI 394

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           A+NKNTVPGDVSA+ P G+R+GTPA+T+RGF  E+F KVAE+ D+AV IA+++K++ QG 
Sbjct: 395 AANKNTVPGDVSALFPSGLRVGTPAMTTRGFGPEEFDKVAEFIDQAVNIAIELKAQEQGK 454

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
             K+ +++ +  +    ++ +L  EV  +  ++P  G
Sbjct: 455 VPKELLASFKKLADESDKVKQLDKEVVSWVSKYPVPG 491

[167][TOP]
>UniRef100_A9TQS1 Serine hydroxymethyltransferase n=1 Tax=Physcomitrella patens
           subsp. patens RepID=A9TQS1_PHYPA
          Length = 478

 Score =  159 bits (402), Expect = 2e-37
 Identities = 79/169 (46%), Positives = 118/169 (69%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  +KAY +QV +N+    + LM++GY++V+GGT+NHLVL +L+P G+ G++VEKV E  
Sbjct: 314 TPLFKAYAKQVKANAKAIGEALMKKGYKMVTGGTENHLVLWDLRPLGLTGNKVEKVCELA 373

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HI  NKN V GD SA+ PGG+R+G PA+TSRG  E+DF ++A++ ++AV I LKV+ E +
Sbjct: 374 HITLNKNAVFGDSSALAPGGVRVGAPAMTSRGLKEKDFEQIADFLERAVNITLKVQKE-R 432

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           G  LK+F   +E++     EIA L+ +VE+F+  F   GF+   +KY N
Sbjct: 433 GKLLKEFNKGLENN----EEIAALKRDVEKFSMSFDMPGFDVNKLKYGN 477

[168][TOP]
>UniRef100_UPI00005A0C12 PREDICTED: similar to serine hydroxymethyltransferase 1 (soluble)
           isoform 1 isoform 2 n=1 Tax=Canis lupus familiaris
           RepID=UPI00005A0C12
          Length = 483

 Score =  159 bits (401), Expect = 2e-37
 Identities = 81/161 (50%), Positives = 112/161 (69%), Gaps = 2/161 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E++ YQ QV++N    A+TLME GY++V+GG+DNHL+LV+L+ KG DG R EKVLEA 
Sbjct: 320 TPEFRLYQHQVVANCRVLAETLMELGYKVVTGGSDNHLILVDLRSKGTDGGRAEKVLEAC 379

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-- 266
            IA NKNT PGD SA+ P G+R+GTPALTSRG +E++F KVA++  + + + L+++++  
Sbjct: 380 SIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKEFQKVAQFVHRGIELTLQIQNDIG 439

Query: 265 AQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
           A+ T LK+F   +      Q  I  LR EVE FA  FP  G
Sbjct: 440 ARAT-LKEFREKLAGDEKHQRAIRALREEVESFASLFPLPG 479

[169][TOP]
>UniRef100_UPI00005A0C11 PREDICTED: similar to serine hydroxymethyltransferase 1 (soluble)
           isoform 1 isoform 1 n=1 Tax=Canis lupus familiaris
           RepID=UPI00005A0C11
          Length = 483

 Score =  159 bits (401), Expect = 2e-37
 Identities = 81/161 (50%), Positives = 112/161 (69%), Gaps = 2/161 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E++ YQ QV++N    A+TLME GY++V+GG+DNHL+LV+L+ KG DG R EKVLEA 
Sbjct: 320 TPEFRLYQHQVVANCRVLAETLMELGYKVVTGGSDNHLILVDLRSKGTDGGRAEKVLEAC 379

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-- 266
            IA NKNT PGD SA+ P G+R+GTPALTSRG +E++F KVA++  + + + L+++++  
Sbjct: 380 SIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKEFQKVAQFVHRGIELTLQIQNDIG 439

Query: 265 AQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
           A+ T LK+F   +      Q  I  LR EVE FA  FP  G
Sbjct: 440 ARAT-LKEFREKLAGDEKHQRAIRALREEVESFASLFPLPG 479

[170][TOP]
>UniRef100_UPI00005A0C0F PREDICTED: similar to serine hydroxymethyltransferase 1 (soluble)
           isoform 2 isoform 4 n=1 Tax=Canis lupus familiaris
           RepID=UPI00005A0C0F
          Length = 444

 Score =  159 bits (401), Expect = 2e-37
 Identities = 81/161 (50%), Positives = 112/161 (69%), Gaps = 2/161 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E++ YQ QV++N    A+TLME GY++V+GG+DNHL+LV+L+ KG DG R EKVLEA 
Sbjct: 281 TPEFRLYQHQVVANCRVLAETLMELGYKVVTGGSDNHLILVDLRSKGTDGGRAEKVLEAC 340

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-- 266
            IA NKNT PGD SA+ P G+R+GTPALTSRG +E++F KVA++  + + + L+++++  
Sbjct: 341 SIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKEFQKVAQFVHRGIELTLQIQNDIG 400

Query: 265 AQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
           A+ T LK+F   +      Q  I  LR EVE FA  FP  G
Sbjct: 401 ARAT-LKEFREKLAGDEKHQRAIRALREEVESFASLFPLPG 440

[171][TOP]
>UniRef100_UPI00005A0C0E PREDICTED: similar to serine hydroxymethyltransferase 1 (soluble)
           isoform 1 isoform 3 n=1 Tax=Canis lupus familiaris
           RepID=UPI00005A0C0E
          Length = 469

 Score =  159 bits (401), Expect = 2e-37
 Identities = 81/161 (50%), Positives = 112/161 (69%), Gaps = 2/161 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E++ YQ QV++N    A+TLME GY++V+GG+DNHL+LV+L+ KG DG R EKVLEA 
Sbjct: 306 TPEFRLYQHQVVANCRVLAETLMELGYKVVTGGSDNHLILVDLRSKGTDGGRAEKVLEAC 365

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-- 266
            IA NKNT PGD SA+ P G+R+GTPALTSRG +E++F KVA++  + + + L+++++  
Sbjct: 366 SIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKEFQKVAQFVHRGIELTLQIQNDIG 425

Query: 265 AQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
           A+ T LK+F   +      Q  I  LR EVE FA  FP  G
Sbjct: 426 ARAT-LKEFREKLAGDEKHQRAIRALREEVESFASLFPLPG 465

[172][TOP]
>UniRef100_Q94JQ3 Serine hydroxymethyltransferase n=1 Tax=Arabidopsis thaliana
           RepID=Q94JQ3_ARATH
          Length = 529

 Score =  159 bits (401), Expect = 2e-37
 Identities = 78/158 (49%), Positives = 111/158 (70%), Gaps = 1/158 (0%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+KAYQ++V+SN    A  L+E G++LVSGG+DNHLVLV+L+P G+DG+RVEK+L+   I
Sbjct: 371 EFKAYQKRVVSNCRALANRLVELGFKLVSGGSDNHLVLVDLRPMGMDGARVEKILDMASI 430

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
             NKN+VPGD SA+VPGGIR+G+PA+T+RG  E+DF  VA++  + V I ++ K  A G+
Sbjct: 431 TLNKNSVPGDKSALVPGGIRIGSPAMTTRGLSEKDFVVVADFIKEGVEITMEAKKAAPGS 490

Query: 253 KLKDFVSAMESSS-TIQSEIAKLRHEVEEFAKQFPTIG 143
           KL+DF   + S    ++  +  L   VE F  +FP  G
Sbjct: 491 KLQDFNKFVTSPEFPLKERVKSLTERVETFTSRFPIPG 528

[173][TOP]
>UniRef100_C4R7T9 Serine hydroxymethyltransferase n=1 Tax=Pichia pastoris GS115
           RepID=C4R7T9_PICPG
          Length = 470

 Score =  158 bits (400), Expect = 3e-37
 Identities = 81/158 (51%), Positives = 110/158 (69%), Gaps = 2/158 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQEQVL N+          GY+LVS GTD+H+VLV+LK K IDG+R+E V E +
Sbjct: 313 TPEFKQYQEQVLKNAKALENEFKRLGYKLVSDGTDSHMVLVSLKDKDIDGARIETVCENI 372

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-- 266
           +IA NKN++PGD SA+VPGG+R+G PA+T+RG  EEDF K+A Y DK+V  A KV+SE  
Sbjct: 373 NIALNKNSIPGDRSALVPGGVRIGAPAMTTRGASEEDFVKIANYIDKSVQYAKKVQSELP 432

Query: 265 AQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 152
            +  KLKDF + +   S    EI +L++E+  +A +FP
Sbjct: 433 IEANKLKDFKAKIAEGS---DEITQLKNEISAWAGEFP 467

[174][TOP]
>UniRef100_B6K5E0 Serine hydroxymethyltransferase n=1 Tax=Schizosaccharomyces
           japonicus yFS275 RepID=B6K5E0_SCHJY
          Length = 460

 Score =  158 bits (400), Expect = 3e-37
 Identities = 80/158 (50%), Positives = 111/158 (70%), Gaps = 3/158 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E++AYQE VL N+    +  + R YELVSGGTD HLVLVNL  KGIDG+RVE+VLE +
Sbjct: 300 TPEFRAYQESVLRNAKALERAFLARNYELVSGGTDTHLVLVNLTSKGIDGARVERVLELI 359

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           +I++NKNTVPGD SA++P G+R+GTPA T+RGF E+DF +V +Y D+AV +  ++ ++A+
Sbjct: 360 NISANKNTVPGDKSALIPHGLRLGTPACTTRGFNEQDFERVVDYIDQAVALTKQINADAK 419

Query: 259 GT---KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQF 155
            T   KL DF   +   S    EI +L+ E+  +A  F
Sbjct: 420 KTGKNKLSDFKQFLGDGSQ-YPEIQRLKSEIGSWASGF 456

[175][TOP]
>UniRef100_UPI0000E80FC6 PREDICTED: similar to serine hydroxymethyltransferase 1 (soluble)
           n=1 Tax=Gallus gallus RepID=UPI0000E80FC6
          Length = 580

 Score =  158 bits (399), Expect = 4e-37
 Identities = 80/160 (50%), Positives = 107/160 (66%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+KAYQ+QV++N    A  LME GY++V+GG+DNHL+L++L+ +G DG R E+VLE  
Sbjct: 418 TPEFKAYQQQVVANCKTLAAALMEMGYDIVTGGSDNHLILLDLRNRGTDGGRAERVLELC 477

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            IA NKNT PGDVSA+ P G+R GTPALTSRGF ++DF  VA Y  K + + L+V+ +  
Sbjct: 478 SIACNKNTCPGDVSALRPSGLRFGTPALTSRGFRQDDFRTVARYIHKGIELTLRVQKDMN 537

Query: 259 -GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   +E     Q E+  L+ EVE FA  FP  G
Sbjct: 538 PKATLKEFKEKLEEEK-YQGELKALKEEVEAFAATFPLPG 576

[176][TOP]
>UniRef100_UPI0000ECABF3 Serine hydroxymethyltransferase, cytosolic (EC 2.1.2.1) (Serine
           methylase) (Glycine hydroxymethyltransferase) (SHMT).
           n=1 Tax=Gallus gallus RepID=UPI0000ECABF3
          Length = 486

 Score =  158 bits (399), Expect = 4e-37
 Identities = 80/160 (50%), Positives = 107/160 (66%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+KAYQ+QV++N    A  LME GY++V+GG+DNHL+L++L+ +G DG R E+VLE  
Sbjct: 324 TPEFKAYQQQVVANCKTLAAALMEMGYDIVTGGSDNHLILLDLRNRGTDGGRAERVLELC 383

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            IA NKNT PGDVSA+ P G+R GTPALTSRGF ++DF  VA Y  K + + L+V+ +  
Sbjct: 384 SIACNKNTCPGDVSALRPSGLRFGTPALTSRGFRQDDFRTVARYIHKGIELTLRVQKDMN 443

Query: 259 -GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   +E     Q E+  L+ EVE FA  FP  G
Sbjct: 444 PKATLKEFKEKLEEEK-YQGELKALKEEVEAFAATFPLPG 482

[177][TOP]
>UniRef100_C7YLG8 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
           RepID=C7YLG8_NECH7
          Length = 504

 Score =  158 bits (399), Expect = 4e-37
 Identities = 85/164 (51%), Positives = 115/164 (70%), Gaps = 10/164 (6%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+  YQ+ VL+N+   +  L   GY+LVSGGTDNHLVLV+LK KG+DG+RVE+VLE V +
Sbjct: 336 EFAEYQKTVLTNAQALSNQLSSLGYKLVSGGTDNHLVLVDLKSKGVDGARVERVLELVGV 395

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKV------K 272
           ASNKNTVPGD SA+ PGG+R+GTPA+T+RGF  EDF +VA+  D+ V I + V       
Sbjct: 396 ASNKNTVPGDRSALKPGGLRLGTPAMTTRGFSAEDFKRVADIVDRGVKITIAVDKDARAA 455

Query: 271 SEAQGTK----LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 152
           +EA+G K    +K F+  +   S+++ EI +LR EVEE+   FP
Sbjct: 456 AEAKGAKNPKTVKAFLEYLGDGSSVK-EIGELRKEVEEWVGGFP 498

[178][TOP]
>UniRef100_A7P4I0 Serine hydroxymethyltransferase n=2 Tax=Vitis vinifera
           RepID=A7P4I0_VITVI
          Length = 428

 Score =  157 bits (398), Expect = 5e-37
 Identities = 77/158 (48%), Positives = 109/158 (68%), Gaps = 1/158 (0%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+KAYQ QV+SN    A  L+E GY LVSGG+DNHL+LV+L+P GIDG+R EK+L+   I
Sbjct: 270 EFKAYQNQVVSNCRALAGRLIELGYNLVSGGSDNHLILVDLRPLGIDGARAEKILDMASI 329

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
             NKN+VPGD SA+VPGGIR+G+PA+T+RGF E++F   A++  + V ++L+ K    G+
Sbjct: 330 TLNKNSVPGDKSALVPGGIRIGSPAMTTRGFSEKEFIATADFIHEGVQLSLEAKKSVSGS 389

Query: 253 KLKDFVSAMESSS-TIQSEIAKLRHEVEEFAKQFPTIG 143
           KL DF+  + S   ++   ++ L+  VE    QFP  G
Sbjct: 390 KLLDFMKFVTSPDFSLIDRVSDLQRRVETLTTQFPMPG 427

[179][TOP]
>UniRef100_UPI0000E48941 PREDICTED: similar to Serine hydroxymethyltransferase 2
           (mitochondrial) n=1 Tax=Strongylocentrotus purpuratus
           RepID=UPI0000E48941
          Length = 278

 Score =  157 bits (398), Expect = 5e-37
 Identities = 78/160 (48%), Positives = 109/160 (68%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  ++ YQ+QVL N    A+ LME+GY LV+GGT+NHLVLV+L+P G DG+R   +L+ V
Sbjct: 120 TPMFREYQDQVLKNCNALAERLMEKGYTLVTGGTENHLVLVDLRPMGGDGTRAGLILDEV 179

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I  NKNT PGD SA+ PGGIR+G PA+TSRGF E DF K A+  ++ + I+L++  +  
Sbjct: 180 SITINKNTCPGDTSALSPGGIRIGAPAMTSRGFSEADFVKCADLVNEGIQISLEINGKV- 238

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGF 140
           G KLKDF + + +   + ++I  LR  VE F +QFP  G+
Sbjct: 239 GKKLKDFKTCLATDPEVAAKINDLRTRVEGFTRQFPMPGY 278

[180][TOP]
>UniRef100_Q6NYR0 Serine hydroxymethyltransferase n=1 Tax=Danio rerio
           RepID=Q6NYR0_DANRE
          Length = 481

 Score =  157 bits (398), Expect = 5e-37
 Identities = 79/160 (49%), Positives = 110/160 (68%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ QVL+N    A  LM++GY++V+GG+DNHL+LV+L+  G DG R EKVLEA 
Sbjct: 318 TPEFKTYQLQVLANCKALASALMDKGYKVVTGGSDNHLILVDLRSNGTDGGRAEKVLEAC 377

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKV-KSEA 263
            IA NKNT PGD SA+ P G+R+G+PALTSRG +EE F KVAE+  + + + L++ K+  
Sbjct: 378 AIACNKNTCPGDKSALRPSGLRLGSPALTSRGLLEEHFHKVAEFIHQGIVLTLEIQKNMN 437

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   +  +   Q +I ++R EVE+FA +FP  G
Sbjct: 438 PKATLKEFKEELAQNEKYQLKIKEIRKEVEDFAGKFPMPG 477

[181][TOP]
>UniRef100_Q2TL58 Serine hydroxymethyltransferase n=1 Tax=Danio rerio
           RepID=Q2TL58_DANRE
          Length = 481

 Score =  157 bits (398), Expect = 5e-37
 Identities = 79/160 (49%), Positives = 110/160 (68%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ QVL+N    A  LM++GY++V+GG+DNHL+LV+L+  G DG R EKVLEA 
Sbjct: 318 TPEFKTYQLQVLANCKALASALMDKGYKVVTGGSDNHLILVDLRSNGTDGGRAEKVLEAC 377

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKV-KSEA 263
            IA NKNT PGD SA+ P G+R+G+PALTSRG +EE F KVAE+  + + + L++ K+  
Sbjct: 378 AIACNKNTCPGDKSALRPSGLRLGSPALTSRGLLEEHFHKVAEFIHQGIVLTLEIQKNMN 437

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   +  +   Q +I ++R EVE+FA +FP  G
Sbjct: 438 PKATLKEFKEELAQNEKYQLKIKEIRKEVEDFAGKFPMPG 477

[182][TOP]
>UniRef100_UPI0001926091 PREDICTED: similar to MGC79128 protein n=1 Tax=Hydra magnipapillata
           RepID=UPI0001926091
          Length = 492

 Score =  157 bits (396), Expect = 9e-37
 Identities = 82/161 (50%), Positives = 108/161 (67%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E++ YQ QVL N+   A+ LM +GY++VS GTDNHLVLV+L+PKGIDGSRVE VL+  
Sbjct: 332 TPEFRDYQVQVLKNAKTMAEQLMAKGYDIVSNGTDNHLVLVDLRPKGIDGSRVEFVLDQA 391

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I +NKNTVPGD SAM P G+R+G  ALTSR F E DF KV +  +K V I L+ +   +
Sbjct: 392 SITANKNTVPGDKSAMKPSGLRLGAAALTSRNFKENDFVKVIDLLNKGVEIGLEAQKLTK 451

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFE 137
              LK++ S  +++ TI   +  LR EV +FA  FP  G +
Sbjct: 452 --TLKEYKSIFKTNRTIMDGVDSLRQEVCQFACTFPMPGLD 490

[183][TOP]
>UniRef100_UPI0000D9E1C1 PREDICTED: similar to serine hydroxymethyltransferase 1 (soluble)
           isoform 1 isoform 6 n=1 Tax=Macaca mulatta
           RepID=UPI0000D9E1C1
          Length = 473

 Score =  157 bits (396), Expect = 9e-37
 Identities = 79/160 (49%), Positives = 109/160 (68%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ QV++N    ++ LME GY++V+GG+DNHL+LV+L+ KG DG R EKVLEA 
Sbjct: 311 TLEFKVYQHQVVANCRALSEALMELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEAC 370

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-A 263
            IA NKNT PGD SA+ P G+R+GTPALTSRG +E+DF KVA++  + + + L+++S+  
Sbjct: 371 SIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAQFIHRGIELTLQIQSDIG 430

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   + +    Q  +  LR EVE FA  FP  G
Sbjct: 431 VRATLKEFKERL-AGDKYQGAVQALREEVESFASLFPLPG 469

[184][TOP]
>UniRef100_UPI0000D9E1C0 PREDICTED: similar to serine hydroxymethyltransferase 1 (soluble)
           isoform 2 isoform 7 n=1 Tax=Macaca mulatta
           RepID=UPI0000D9E1C0
          Length = 444

 Score =  157 bits (396), Expect = 9e-37
 Identities = 79/160 (49%), Positives = 109/160 (68%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ QV++N    ++ LME GY++V+GG+DNHL+LV+L+ KG DG R EKVLEA 
Sbjct: 282 TLEFKVYQHQVVANCRALSEALMELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEAC 341

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-A 263
            IA NKNT PGD SA+ P G+R+GTPALTSRG +E+DF KVA++  + + + L+++S+  
Sbjct: 342 SIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAQFIHRGIELTLQIQSDIG 401

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   + +    Q  +  LR EVE FA  FP  G
Sbjct: 402 VRATLKEFKERL-AGDKYQGAVQALREEVESFASLFPLPG 440

[185][TOP]
>UniRef100_UPI0000D9E1BE PREDICTED: similar to serine hydroxymethyltransferase 1 (soluble)
           isoform 1 isoform 2 n=1 Tax=Macaca mulatta
           RepID=UPI0000D9E1BE
          Length = 483

 Score =  157 bits (396), Expect = 9e-37
 Identities = 79/160 (49%), Positives = 109/160 (68%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ QV++N    ++ LME GY++V+GG+DNHL+LV+L+ KG DG R EKVLEA 
Sbjct: 321 TLEFKVYQHQVVANCRALSEALMELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEAC 380

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-A 263
            IA NKNT PGD SA+ P G+R+GTPALTSRG +E+DF KVA++  + + + L+++S+  
Sbjct: 381 SIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAQFIHRGIELTLQIQSDIG 440

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   + +    Q  +  LR EVE FA  FP  G
Sbjct: 441 VRATLKEFKERL-AGDKYQGAVQALREEVESFASLFPLPG 479

[186][TOP]
>UniRef100_C1GCX5 Serine hydroxymethyltransferase n=1 Tax=Paracoccidioides
           brasiliensis Pb18 RepID=C1GCX5_PARBD
          Length = 471

 Score =  157 bits (396), Expect = 9e-37
 Identities = 80/158 (50%), Positives = 108/158 (68%), Gaps = 2/158 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQEQVL N+        + GY+LVS GTD+H+VL++L PK +DG+RVE VLE +
Sbjct: 313 TPEFKQYQEQVLKNAKALEHEFKKLGYKLVSDGTDSHMVLLDLTPKALDGARVEAVLEQI 372

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-- 266
           +IA NKN++PGD SA+ PGGIR+G PA+TSRG  EEDF ++A + DKA+ I   V+SE  
Sbjct: 373 NIACNKNSIPGDKSALSPGGIRIGAPAMTSRGMGEEDFKRIANFIDKAINICKSVQSELP 432

Query: 265 AQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 152
               KLKDF + + S +    EI  LR ++ E+A  FP
Sbjct: 433 KNANKLKDFKAKVASETV--PEILTLRKDIAEWASTFP 468

[187][TOP]
>UniRef100_C0SHS9 Serine hydroxymethyltransferase n=1 Tax=Paracoccidioides
           brasiliensis Pb03 RepID=C0SHS9_PARBP
          Length = 471

 Score =  157 bits (396), Expect = 9e-37
 Identities = 80/158 (50%), Positives = 108/158 (68%), Gaps = 2/158 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQEQVL N+        + GY+LVS GTD+H+VL++L PK +DG+RVE VLE +
Sbjct: 313 TPEFKQYQEQVLKNAKALEHEFKKLGYKLVSDGTDSHMVLLDLTPKALDGARVEAVLEQI 372

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-- 266
           +IA NKN++PGD SA+ PGGIR+G PA+TSRG  EEDF ++A + DKA+ I   V+SE  
Sbjct: 373 NIACNKNSIPGDKSALSPGGIRIGAPAMTSRGMGEEDFKRIANFIDKAINICKSVQSELP 432

Query: 265 AQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 152
               KLKDF + + S +    EI  LR ++ E+A  FP
Sbjct: 433 KNANKLKDFKAKVASETV--PEIITLRKDIAEWASTFP 468

[188][TOP]
>UniRef100_Q6C859 Serine hydroxymethyltransferase n=1 Tax=Yarrowia lipolytica
           RepID=Q6C859_YARLI
          Length = 481

 Score =  156 bits (395), Expect = 1e-36
 Identities = 76/154 (49%), Positives = 114/154 (74%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+K YQ++V+ N+  F++ L + G++LVS GTD HL+L++LKP  IDG+R E VL+ ++I
Sbjct: 320 EFKEYQQKVVDNAQAFSKALSDAGFKLVSDGTDTHLILIDLKPFSIDGARTEMVLDGMNI 379

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           A+NKNTVPGD SA+VPGGIR+GTPA+T+RGF + +F +VA+Y  KAV IA ++K +A   
Sbjct: 380 AANKNTVPGDKSALVPGGIRIGTPAMTTRGFDQSEFEQVAKYIVKAVDIAKRLKQKAVSE 439

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 152
            +K  +S         +E+ +LR+EVE +AK++P
Sbjct: 440 GVKK-ISQFRPYVDADAEVKELRNEVESWAKKYP 472

[189][TOP]
>UniRef100_Q7SXN1 Serine hydroxymethyltransferase n=1 Tax=Danio rerio
           RepID=Q7SXN1_DANRE
          Length = 481

 Score =  156 bits (394), Expect = 1e-36
 Identities = 78/160 (48%), Positives = 109/160 (68%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ QVL+N    A  LM++GY++V+GG+DNHL+LV+L+  G DG R EKVLEA 
Sbjct: 318 TPEFKTYQLQVLANCKALASALMDKGYKVVTGGSDNHLILVDLRSNGTDGGRAEKVLEAC 377

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKV-KSEA 263
            IA NKNT PGD SA+ P G+R+G+PALTSRG +EE F KVAE+  + + + L++ K+  
Sbjct: 378 AIACNKNTCPGDKSALRPSGLRLGSPALTSRGLLEEHFHKVAEFIHQGIVLTLEIQKNMN 437

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   +  +   Q +  ++R EVE+FA +FP  G
Sbjct: 438 PKATLKEFKEELSQNEKYQLKTKEIRKEVEDFAGKFPMPG 477

[190][TOP]
>UniRef100_C5LR27 Serine hydroxymethyltransferase n=1 Tax=Perkinsus marinus ATCC
           50983 RepID=C5LR27_9ALVE
          Length = 460

 Score =  156 bits (394), Expect = 1e-36
 Identities = 79/159 (49%), Positives = 115/159 (72%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EYK YQ+QV+ NS   A  L++ GY+LVSGGTDNHLVL++L+ +GI+G++ EK+ + V
Sbjct: 304 TEEYKQYQQQVVKNSKALADELIKLGYDLVSGGTDNHLVLLDLRSRGINGNKTEKLCDHV 363

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I+ NKNTVPGD SA+ P G+R+G PA+T+RG  EEDF K+A++  + V I L+V+ ++ 
Sbjct: 364 AISLNKNTVPGDKSAITPSGLRIGAPAMTTRGAKEEDFRKIAQFIHRVVEIGLQVQKQS- 422

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
           G KLKDF++ ++  +T   E+ +LR EV  F+  F  IG
Sbjct: 423 GPKLKDFLAILD--NTPPPELTQLREEVMAFSCGFVPIG 459

[191][TOP]
>UniRef100_A4H7V2 Serine hydroxymethyltransferase n=1 Tax=Leishmania braziliensis
           RepID=A4H7V2_LEIBR
          Length = 465

 Score =  156 bits (394), Expect = 1e-36
 Identities = 79/168 (47%), Positives = 113/168 (67%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K Y +QV SN+   A  L  +G++ VSGGTDNHL+L N++  G+ GS++EK+L+AV
Sbjct: 295 TPEWKVYAKQVQSNARTLAAALSAKGHKFVSGGTDNHLLLWNVRVHGLTGSKMEKLLDAV 354

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            ++ NKNT+PGD SAM PGGIR+GT +LTSRG VE D   +AE+ D+A+ +A ++++E  
Sbjct: 355 SVSVNKNTIPGDKSAMTPGGIRVGTLSLTSRGMVEADMRVIAEFLDRAIELAKQIQTEVG 414

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYK 116
             KL DFV A+       S +A LR +VE FA  F    F+   +KY+
Sbjct: 415 SAKLNDFVEALPK----YSGVAALRRDVEAFATTFAIPTFDVARIKYQ 458

[192][TOP]
>UniRef100_UPI0000E49DF3 PREDICTED: similar to serine hydroxymethyltransferase isoform 1 n=2
           Tax=Strongylocentrotus purpuratus RepID=UPI0000E49DF3
          Length = 496

 Score =  155 bits (393), Expect = 2e-36
 Identities = 77/159 (48%), Positives = 105/159 (66%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+K Y   V++N+   A+ LM+RGY + SGGTD HL+L++L+P G+DG+R E VLE V I
Sbjct: 336 EFKLYARDVVTNAQAMAEELMKRGYTISSGGTDTHLLLLDLRPLGLDGARGEFVLERVGI 395

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
             NKNT PGD SA+ PGG+R+GTPALTSR F   DF  V +Y D+ + +  +   +   T
Sbjct: 396 VLNKNTCPGDKSALKPGGLRIGTPALTSRNFKVTDFMMVVDYIDRGLKLTAEANKKCSST 455

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFE 137
            L+DF + + S S  QS++A L  EVE FA +FP  G E
Sbjct: 456 TLRDFKAYVTSDSDFQSKLAALEKEVESFAVRFPLPGHE 494

[193][TOP]
>UniRef100_UPI0000E49DF2 PREDICTED: similar to serine hydroxymethyltransferase isoform 2 n=1
           Tax=Strongylocentrotus purpuratus RepID=UPI0000E49DF2
          Length = 534

 Score =  155 bits (393), Expect = 2e-36
 Identities = 77/159 (48%), Positives = 105/159 (66%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+K Y   V++N+   A+ LM+RGY + SGGTD HL+L++L+P G+DG+R E VLE V I
Sbjct: 374 EFKLYARDVVTNAQAMAEELMKRGYTISSGGTDTHLLLLDLRPLGLDGARGEFVLERVGI 433

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
             NKNT PGD SA+ PGG+R+GTPALTSR F   DF  V +Y D+ + +  +   +   T
Sbjct: 434 VLNKNTCPGDKSALKPGGLRIGTPALTSRNFKVTDFMMVVDYIDRGLKLTAEANKKCSST 493

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFE 137
            L+DF + + S S  QS++A L  EVE FA +FP  G E
Sbjct: 494 TLRDFKAYVTSDSDFQSKLAALEKEVESFAVRFPLPGHE 532

[194][TOP]
>UniRef100_UPI0000585236 PREDICTED: similar to serine hydroxymethyltransferase isoform 2 n=1
           Tax=Strongylocentrotus purpuratus RepID=UPI0000585236
          Length = 518

 Score =  155 bits (393), Expect = 2e-36
 Identities = 77/159 (48%), Positives = 105/159 (66%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+K Y   V++N+   A+ LM+RGY + SGGTD HL+L++L+P G+DG+R E VLE V I
Sbjct: 358 EFKLYARDVVTNAQAMAEELMKRGYTISSGGTDTHLLLLDLRPLGLDGARGEFVLERVGI 417

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
             NKNT PGD SA+ PGG+R+GTPALTSR F   DF  V +Y D+ + +  +   +   T
Sbjct: 418 VLNKNTCPGDKSALKPGGLRIGTPALTSRNFKVTDFMMVVDYIDRGLKLTAEANKKCSST 477

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFE 137
            L+DF + + S S  QS++A L  EVE FA +FP  G E
Sbjct: 478 TLRDFKAYVTSDSDFQSKLAALEKEVESFAVRFPLPGHE 516

[195][TOP]
>UniRef100_UPI00004D312F UPI00004D312F related cluster n=1 Tax=Xenopus (Silurana) tropicalis
           RepID=UPI00004D312F
          Length = 485

 Score =  155 bits (393), Expect = 2e-36
 Identities = 79/158 (50%), Positives = 105/158 (66%), Gaps = 1/158 (0%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+K YQ QV+SN    +  + E GY +V+GG+DNHL+LVNL+ +  DG R EKVLEA  I
Sbjct: 324 EFKLYQRQVVSNCKALSSAMEELGYHVVTGGSDNHLILVNLRGQKTDGGRAEKVLEACAI 383

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-AQG 257
           A NKNT PGD SA+ P G+R+GTPALTSRGF EEDF KVA++  + + + L++++    G
Sbjct: 384 ACNKNTCPGDKSALRPSGLRLGTPALTSRGFKEEDFKKVAQFIHRGIELTLEIQNAMIPG 443

Query: 256 TKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
             LKDF   + S      ++  LR EVE+FA  FP  G
Sbjct: 444 ATLKDFKEKLASEDVHTPKMLALREEVEKFAGTFPIPG 481

[196][TOP]
>UniRef100_Q8W524 Serine hydroxymethyltransferase (Fragment) n=1 Tax=Zea mays
           RepID=Q8W524_MAIZE
          Length = 343

 Score =  155 bits (393), Expect = 2e-36
 Identities = 76/87 (87%), Positives = 83/87 (95%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T EY+AYQEQV+SN AKFAQ+L+ +GYELVSGGTDNHLVLVNLK KGIDGSRVEKVLE+V
Sbjct: 257 TPEYRAYQEQVISNCAKFAQSLISKGYELVSGGTDNHLVLVNLKNKGIDGSRVEKVLESV 316

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPA 359
           HIA+NKNTVPGDVSAMVPGGIRMGTPA
Sbjct: 317 HIAANKNTVPGDVSAMVPGGIRMGTPA 343

[197][TOP]
>UniRef100_B8CCS6 Serine hydroxymethyltransferase n=1 Tax=Thalassiosira pseudonana
           CCMP1335 RepID=B8CCS6_THAPS
          Length = 476

 Score =  155 bits (393), Expect = 2e-36
 Identities = 82/168 (48%), Positives = 109/168 (64%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+  Y  QV  N+      L+  GY L +GGT+NHLVL +LKP+ + GS+ EKV +AV
Sbjct: 313 TPEFHQYSAQVRKNAQALGNKLISLGYSLATGGTENHLVLWDLKPQKLTGSKFEKVCDAV 372

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I  NKN VPGD SA+ PGG+R+G PALT+R  VE DF ++A +  +A+TIALK++ E+ 
Sbjct: 373 SITLNKNCVPGDRSAVTPGGVRIGAPALTTRKMVEADFEQIAMFLHEALTIALKIQEES- 431

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYK 116
           G KL DFV  +E +     E+  LR  V EFA  FP  GF+ + MKYK
Sbjct: 432 GPKLVDFVKCLEQN----GEVEGLRKRVNEFASGFPMPGFDPKEMKYK 475

[198][TOP]
>UniRef100_Q2F5L3 Serine hydroxymethyltransferase n=1 Tax=Bombyx mori
           RepID=Q2F5L3_BOMMO
          Length = 465

 Score =  155 bits (393), Expect = 2e-36
 Identities = 75/162 (46%), Positives = 111/162 (68%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T+E+  YQ+QV+ N+ +  + L+ RGY + +GGTD HL LV+L+  G+ G+  E+VLE  
Sbjct: 304 TTEFVEYQKQVIKNAQRLCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELC 363

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            +A NKNTVPGD+SA+ P GIR+GTPALT+RG  E D  KV ++ D+A+ I L++  +  
Sbjct: 364 SVACNKNTVPGDISALNPSGIRLGTPALTTRGLKEADIDKVVDFIDRALKIGLEI-IKVS 422

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
           G KL DF  A+E ++  + +I  L+ EVE ++K FP  GF+K
Sbjct: 423 GLKLVDFNKAIEENAEFKKKIENLKEEVENYSKSFPLPGFDK 464

[199][TOP]
>UniRef100_A6S2X4 Serine hydroxymethyltransferase n=1 Tax=Botryotinia fuckeliana
           B05.10 RepID=A6S2X4_BOTFB
          Length = 516

 Score =  155 bits (393), Expect = 2e-36
 Identities = 86/169 (50%), Positives = 117/169 (69%), Gaps = 16/169 (9%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMER------GYELVSGGTDNHLVLVNLKPKGIDGSRVEKV 452
           E++AYQE VL N+  FA+ L +       GY +VSGGTDNHLVL++LKP+G+DG+RVE+V
Sbjct: 341 EFRAYQEAVLLNAKAFAKRLGDSKDKGGLGYSIVSGGTDNHLVLIDLKPQGVDGARVERV 400

Query: 451 LEAVHIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKV- 275
           LE V +ASNKNTVPGD SA+ PGG+RMGTPA+T+RGF  EDF +VA+  ++AVTI  ++ 
Sbjct: 401 LELVGVASNKNTVPGDKSALKPGGLRMGTPAMTTRGFQPEDFVRVADVVNRAVTITQRLD 460

Query: 274 -----KSEAQGTK----LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQF 155
                 +EA+G K    +K F+  +      + EI +LR EVEE+   F
Sbjct: 461 KSAREAAEAKGRKNPGSVKAFLEYLGEGEN-EREIVQLRSEVEEWVGTF 508

[200][TOP]
>UniRef100_UPI0000EDD54A PREDICTED: similar to Serine hydroxymethyltransferase 1 (soluble)
           n=1 Tax=Ornithorhynchus anatinus RepID=UPI0000EDD54A
          Length = 484

 Score =  155 bits (392), Expect = 3e-36
 Identities = 79/160 (49%), Positives = 104/160 (65%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ+QV++N    +  + E GY +V+GG+DNHL+LV+L+ KG DG R EKVLEA 
Sbjct: 321 TPEFKVYQQQVVANCKALSAAMTELGYHVVTGGSDNHLILVDLRNKGTDGGRAEKVLEAC 380

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-A 263
            IA NKNT PGD SA+ P G+R+GTPALTSRG +E DF KVA +  + + +   ++SE A
Sbjct: 381 SIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLENDFKKVAYFIHRGIELTRMIQSEMA 440

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   +      QS I  +R EVE FA  FP  G
Sbjct: 441 AKATLKEFKERLAGDEKYQSIIKSIREEVEAFASVFPLPG 480

[201][TOP]
>UniRef100_UPI00005EB8A8 PREDICTED: similar to cytosolic serine hydroxymethyltransferase n=1
           Tax=Monodelphis domestica RepID=UPI00005EB8A8
          Length = 484

 Score =  155 bits (392), Expect = 3e-36
 Identities = 77/161 (47%), Positives = 110/161 (68%), Gaps = 2/161 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+KAYQ+QV++N       LME GY +V+GG+DNHL+L++L+ KG DG R EKVLE+ 
Sbjct: 321 TPEFKAYQQQVVANCKALCAALMELGYHIVTGGSDNHLILLDLRSKGTDGGRAEKVLESC 380

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEA- 263
            IA NKNT PGD SA+ P G+R+GTPALTSRG +E+DF +VA++  + + +AL+++ +  
Sbjct: 381 SIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKDFHQVAQFIHEGIELALRIQRDVG 440

Query: 262 -QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
            Q T +K+F   +   +  Q  +  LR +VE FA  FP  G
Sbjct: 441 PQAT-MKEFKEKLAGDAHYQGAVKALRDKVESFATTFPLPG 480

[202][TOP]
>UniRef100_UPI0001796D23 PREDICTED: similar to serine hydroxymethyltransferase 1 (soluble)
           n=1 Tax=Equus caballus RepID=UPI0001796D23
          Length = 575

 Score =  155 bits (391), Expect = 3e-36
 Identities = 78/161 (48%), Positives = 109/161 (67%), Gaps = 2/161 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E++ YQ QV++N    A++LM  GY +V+GG+DNHL+LV+L+ KG DG R EKVLEA 
Sbjct: 412 TPEFRLYQRQVVANCRALAESLMALGYTVVTGGSDNHLILVDLRSKGTDGGRAEKVLEAC 471

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            IA NKNT PGD SA+ P G+R+GTPALTSRG +E++F KVA++  + + + L+++++  
Sbjct: 472 SIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKEFQKVAQFIHRGIELTLQIQNDV- 530

Query: 259 GTK--LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
           G K  LK+F   +      Q  +  LR EVE FA  FP  G
Sbjct: 531 GIKATLKEFKEKLAGDEKHQQAVRALREEVESFASLFPLPG 571

[203][TOP]
>UniRef100_A8P0J8 Serine hydroxymethyltransferase n=1 Tax=Coprinopsis cinerea
           okayama7#130 RepID=A8P0J8_COPC7
          Length = 480

 Score =  155 bits (391), Expect = 3e-36
 Identities = 81/167 (48%), Positives = 114/167 (68%), Gaps = 3/167 (1%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+KAY +QV++N+   A+TL+  GY+L +GGTDNHLVL +L+P G+ GS+VEKV + + I
Sbjct: 305 EWKAYAKQVVANARALAETLVGHGYKLQTGGTDNHLVLWDLRPIGLTGSKVEKVCDLMGI 364

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
             NKN V GD SA VPGGIR+GT ALTSR   EED  +VAE+  +AV I+L ++ EA   
Sbjct: 365 TINKNAVSGDASAQVPGGIRLGTSALTSRDMREEDVKQVAEFLHRAVQISLTLQKEAGTK 424

Query: 253 KLKDFV---SAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMK 122
            LKDFV   +  E       ++++LR EV+ FAK+FP  G + + ++
Sbjct: 425 LLKDFVRVATTKEEGKVGYEQVSQLREEVQAFAKRFPLPGVDTQNLQ 471

[204][TOP]
>UniRef100_A7EEI9 Serine hydroxymethyltransferase n=1 Tax=Sclerotinia sclerotiorum
           1980 UF-70 RepID=A7EEI9_SCLS1
          Length = 521

 Score =  155 bits (391), Expect = 3e-36
 Identities = 86/169 (50%), Positives = 116/169 (68%), Gaps = 16/169 (9%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMER------GYELVSGGTDNHLVLVNLKPKGIDGSRVEKV 452
           E++AYQE VL N+  FA+ L +       GY +VSGGTDNHLVL++LKP+G+DG+RVE+V
Sbjct: 346 EFRAYQEAVLLNAKAFAKRLGDSKDKGGLGYSIVSGGTDNHLVLIDLKPQGVDGARVERV 405

Query: 451 LEAVHIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTI----- 287
           LE V +ASNKNTVPGD SA+ PGG+RMGTPA+T+RGF  +DF +VA+  ++AVTI     
Sbjct: 406 LELVGVASNKNTVPGDKSALKPGGLRMGTPAMTTRGFQPDDFVRVADVVNRAVTITQRLD 465

Query: 286 -ALKVKSEAQGTK----LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQF 155
              K  +EA+G K    +K F+  +      + EI +LR EVEE+   F
Sbjct: 466 KTAKEAAEAKGRKNPGSVKAFLEYLGEGEN-EREIVQLRSEVEEWVGTF 513

[205][TOP]
>UniRef100_A5E6C0 Serine hydroxymethyltransferase n=1 Tax=Lodderomyces elongisporus
           RepID=A5E6C0_LODEL
          Length = 486

 Score =  155 bits (391), Expect = 3e-36
 Identities = 73/157 (46%), Positives = 110/157 (70%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           +YK YQ+ V+ N+  FA  L  +G++LVSGGTD HL+LV+L  K IDG+RVE VLE  +I
Sbjct: 328 DYKKYQQAVVDNAKHFANELQSKGFDLVSGGTDTHLILVDLSSKKIDGARVEAVLERANI 387

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           A+NKNT+PGD SA+ P G+R+GTPA+T+RGF  ++F KVAE  D+AV IA+++K++ QG 
Sbjct: 388 AANKNTIPGDTSALFPSGLRVGTPAMTTRGFGFDEFTKVAELMDEAVAIAIELKAKEQGK 447

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
             K+ +++ +  +    ++ +L   V E+   +P  G
Sbjct: 448 VPKELLASFKKLADESDKVKELGQRVAEWTTTYPVPG 484

[206][TOP]
>UniRef100_UPI0000EB3F8C Serine hydroxymethyltransferase, cytosolic (EC 2.1.2.1) (Serine
           methylase) (Glycine hydroxymethyltransferase) (SHMT).
           n=1 Tax=Canis lupus familiaris RepID=UPI0000EB3F8C
          Length = 486

 Score =  154 bits (389), Expect = 6e-36
 Identities = 82/163 (50%), Positives = 109/163 (66%), Gaps = 4/163 (2%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E++ YQ QV++N    A+TLME GY++V+GG+DNHL+LV+L+ KG DG R EKVLEA 
Sbjct: 321 TPEFRLYQHQVVANCRVLAETLMELGYKVVTGGSDNHLILVDLRSKGTDGGRAEKVLEAC 380

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-- 266
            IA NKNT PGD SA+ P G+R+GTPALTSRG +E++F KVA++  +   I L ++ +  
Sbjct: 381 SIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKEFQKVAQFVHRGTGIELTLQIQND 440

Query: 265 --AQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
             A+ T LK+F   +      Q  I  LR EVE FA  FP  G
Sbjct: 441 IGARAT-LKEFREKLAGDEKHQRAIRALREEVESFASLFPLPG 482

[207][TOP]
>UniRef100_A4HGU0 Serine hydroxymethyltransferase n=1 Tax=Leishmania braziliensis
           RepID=A4HGU0_LEIBR
          Length = 465

 Score =  154 bits (389), Expect = 6e-36
 Identities = 79/159 (49%), Positives = 110/159 (69%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E++AY +QV +N+   A  L E G  LVSGGTDNHL+L NL P GI GS+VEK+L+  HI
Sbjct: 305 EWRAYAKQVKANAKALAAALTESGEALVSGGTDNHLLLWNLNPHGITGSKVEKLLDMAHI 364

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
             NKNT+ GD SA  P GIR+GTPALT+RGF E+DF +VA++  ++V ++ +V+  A   
Sbjct: 365 TVNKNTIVGDKSAQAPYGIRLGTPALTTRGFQEKDFKQVAQFLIRSVHLSKEVQKSAGSM 424

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFE 137
           KL DFV A E+S+ +Q    ++  EV+ +A+Q+P  G E
Sbjct: 425 KLADFVKAAETSTALQ----EMAEEVKAYARQYPYPGLE 459

[208][TOP]
>UniRef100_Q53ET7 Serine hydroxymethyltransferase (Fragment) n=1 Tax=Homo sapiens
           RepID=Q53ET7_HUMAN
          Length = 483

 Score =  154 bits (389), Expect = 6e-36
 Identities = 78/160 (48%), Positives = 108/160 (67%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ QV++N    ++ L E GY++V+GG+DNHL+LV+L+ KG DG R EKVLEA 
Sbjct: 321 TLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEAC 380

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-A 263
            IA NKNT PGD SA+ P G+R+GTPALTSRG +E+DF KVA +  + + + L+++S+  
Sbjct: 381 SIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTG 440

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   + +    Q+ +  LR EVE FA  FP  G
Sbjct: 441 VRATLKEFKERL-AGDKYQAAVQALREEVESFASLFPLPG 479

[209][TOP]
>UniRef100_B4DPM9 Serine hydroxymethyltransferase n=2 Tax=Homo sapiens
           RepID=B4DPM9_HUMAN
          Length = 345

 Score =  154 bits (389), Expect = 6e-36
 Identities = 78/160 (48%), Positives = 108/160 (67%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ QV++N    ++ L E GY++V+GG+DNHL+LV+L+ KG DG R EKVLEA 
Sbjct: 183 TLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEAC 242

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-A 263
            IA NKNT PGD SA+ P G+R+GTPALTSRG +E+DF KVA +  + + + L+++S+  
Sbjct: 243 SIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTG 302

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   + +    Q+ +  LR EVE FA  FP  G
Sbjct: 303 VRATLKEFKERL-AGDKYQAAVQALREEVESFASLFPLPG 341

[210][TOP]
>UniRef100_Q6CKQ4 Serine hydroxymethyltransferase n=1 Tax=Kluyveromyces lactis
           RepID=Q6CKQ4_KLULA
          Length = 469

 Score =  154 bits (389), Expect = 6e-36
 Identities = 75/158 (47%), Positives = 111/158 (70%), Gaps = 2/158 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ QVL N+    ++  + GY LVS GTD+H+VLV+L+ KG+DG+RVE V E +
Sbjct: 312 TPEFKEYQTQVLKNAKVLEESFKKLGYRLVSDGTDSHMVLVSLREKGVDGARVEYVCENI 371

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-- 266
           +IA NKN++PGD SA+VPGG+R+G PA+T+RGF E +FA++ +Y DKAV  A K +    
Sbjct: 372 NIALNKNSIPGDKSALVPGGVRIGAPAMTTRGFGEPEFARIVDYIDKAVQFAAKTQQSLP 431

Query: 265 AQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 152
            +  KLKDF + +   S    E+ +L++E+ ++A +FP
Sbjct: 432 KEANKLKDFKAKVNEGS---EELTQLKNEIYQWAGEFP 466

[211][TOP]
>UniRef100_P34896-2 Isoform 2 of Serine hydroxymethyltransferase, cytosolic n=1
           Tax=Homo sapiens RepID=P34896-2
          Length = 444

 Score =  154 bits (389), Expect = 6e-36
 Identities = 78/160 (48%), Positives = 108/160 (67%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ QV++N    ++ L E GY++V+GG+DNHL+LV+L+ KG DG R EKVLEA 
Sbjct: 282 TLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEAC 341

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-A 263
            IA NKNT PGD SA+ P G+R+GTPALTSRG +E+DF KVA +  + + + L+++S+  
Sbjct: 342 SIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTG 401

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   + +    Q+ +  LR EVE FA  FP  G
Sbjct: 402 VRATLKEFKERL-AGDKYQAAVQALREEVESFASLFPLPG 440

[212][TOP]
>UniRef100_P34896 Serine hydroxymethyltransferase, cytosolic n=1 Tax=Homo sapiens
           RepID=GLYC_HUMAN
          Length = 483

 Score =  154 bits (389), Expect = 6e-36
 Identities = 78/160 (48%), Positives = 108/160 (67%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ QV++N    ++ L E GY++V+GG+DNHL+LV+L+ KG DG R EKVLEA 
Sbjct: 321 TLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEAC 380

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-A 263
            IA NKNT PGD SA+ P G+R+GTPALTSRG +E+DF KVA +  + + + L+++S+  
Sbjct: 381 SIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTG 440

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   + +    Q+ +  LR EVE FA  FP  G
Sbjct: 441 VRATLKEFKERL-AGDKYQAAVQALREEVESFASLFPLPG 479

[213][TOP]
>UniRef100_UPI0000E248E0 PREDICTED: serine hydroxymethyltransferase 1 (soluble) isoform 5
           n=1 Tax=Pan troglodytes RepID=UPI0000E248E0
          Length = 473

 Score =  154 bits (388), Expect = 7e-36
 Identities = 78/160 (48%), Positives = 108/160 (67%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ QV++N    ++ L E GY++V+GG+DNHL+LV+L+ KG DG R EKVLEA 
Sbjct: 311 TLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEAC 370

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-A 263
            IA NKNT PGD SA+ P G+R+GTPALTSRG +E+DF KVA +  + + + L+++S+  
Sbjct: 371 SIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTG 430

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   + +    Q+ +  LR EVE FA  FP  G
Sbjct: 431 VRATLKEFKERL-AGDKYQAVVQALREEVESFASLFPLPG 469

[214][TOP]
>UniRef100_UPI000036AB45 PREDICTED: serine hydroxymethyltransferase 1 (soluble) isoform 6
           n=1 Tax=Pan troglodytes RepID=UPI000036AB45
          Length = 483

 Score =  154 bits (388), Expect = 7e-36
 Identities = 78/160 (48%), Positives = 108/160 (67%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ QV++N    ++ L E GY++V+GG+DNHL+LV+L+ KG DG R EKVLEA 
Sbjct: 321 TLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEAC 380

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-A 263
            IA NKNT PGD SA+ P G+R+GTPALTSRG +E+DF KVA +  + + + L+++S+  
Sbjct: 381 SIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTG 440

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   + +    Q+ +  LR EVE FA  FP  G
Sbjct: 441 VRATLKEFKERL-AGDKYQAVVQALREEVESFASLFPLPG 479

[215][TOP]
>UniRef100_UPI000036AB44 PREDICTED: serine hydroxymethyltransferase 1 (soluble) isoform 8
           n=1 Tax=Pan troglodytes RepID=UPI000036AB44
          Length = 444

 Score =  154 bits (388), Expect = 7e-36
 Identities = 78/160 (48%), Positives = 108/160 (67%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ QV++N    ++ L E GY++V+GG+DNHL+LV+L+ KG DG R EKVLEA 
Sbjct: 282 TLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEAC 341

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-A 263
            IA NKNT PGD SA+ P G+R+GTPALTSRG +E+DF KVA +  + + + L+++S+  
Sbjct: 342 SIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTG 401

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   + +    Q+ +  LR EVE FA  FP  G
Sbjct: 402 VRATLKEFKERL-AGDKYQAVVQALREEVESFASLFPLPG 440

[216][TOP]
>UniRef100_Q28CF2 Serine hydroxymethyltransferase n=1 Tax=Xenopus (Silurana)
           tropicalis RepID=Q28CF2_XENTR
          Length = 485

 Score =  154 bits (388), Expect = 7e-36
 Identities = 78/158 (49%), Positives = 105/158 (66%), Gaps = 1/158 (0%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+K YQ QV+SN    +  + E GY +V+GG+DNHL+LVNL+ +  DG R EKVLEA  I
Sbjct: 324 EFKLYQRQVVSNCKALSSAMEELGYHVVTGGSDNHLILVNLRGQKTDGGRAEKVLEACAI 383

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-AQG 257
           A NKNT PGD SA+ P G+R+GTPALTSRGF E+DF KVA++  + + + L++++    G
Sbjct: 384 ACNKNTCPGDKSALRPSGLRLGTPALTSRGFKEDDFKKVAQFIHRGIELTLEIQNAMIPG 443

Query: 256 TKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
             LKDF   + S      ++  LR EVE+FA  FP  G
Sbjct: 444 ATLKDFKEKLASEDVHTPKMLALRAEVEKFAGTFPIPG 481

[217][TOP]
>UniRef100_Q17I00 Serine hydroxymethyltransferase n=1 Tax=Aedes aegypti
           RepID=Q17I00_AEDAE
          Length = 573

 Score =  154 bits (388), Expect = 7e-36
 Identities = 73/162 (45%), Positives = 109/162 (67%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ Q++ N+    + L+ERGY + +GGTD HLVLV+L+P GI G+R E VLE +
Sbjct: 412 TPEFKDYQTQIIRNAQALCKGLLERGYSISTGGTDVHLVLVDLRPAGITGARAEYVLEEI 471

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            IA NKNTVPGD SA+ P GIR+GTPALT+RG VE D   V ++ D+ + ++ ++ +   
Sbjct: 472 SIACNKNTVPGDKSALNPSGIRLGTPALTTRGLVESDMTHVVDFIDRGLKLSKEI-TAVS 530

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
           G KL DF   +    T+ +++  L+ EV+ ++ +FP  G+E+
Sbjct: 531 GPKLVDFKRVLHEDPTLNAKVQALKEEVQAYSAKFPMPGYEE 572

[218][TOP]
>UniRef100_Q17HZ9 Serine hydroxymethyltransferase n=1 Tax=Aedes aegypti
           RepID=Q17HZ9_AEDAE
          Length = 475

 Score =  154 bits (388), Expect = 7e-36
 Identities = 73/162 (45%), Positives = 109/162 (67%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ Q++ N+    + L+ERGY + +GGTD HLVLV+L+P GI G+R E VLE +
Sbjct: 314 TPEFKDYQTQIIRNAQALCKGLLERGYSISTGGTDVHLVLVDLRPAGITGARAEYVLEEI 373

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            IA NKNTVPGD SA+ P GIR+GTPALT+RG VE D   V ++ D+ + ++ ++ +   
Sbjct: 374 SIACNKNTVPGDKSALNPSGIRLGTPALTTRGLVESDMTHVVDFIDRGLKLSKEI-TAVS 432

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEK 134
           G KL DF   +    T+ +++  L+ EV+ ++ +FP  G+E+
Sbjct: 433 GPKLVDFKRVLHEDPTLNAKVQALKEEVQAYSAKFPMPGYEE 474

[219][TOP]
>UniRef100_Q10104 Probable serine hydroxymethyltransferase, cytosolic n=1
           Tax=Schizosaccharomyces pombe RepID=GLYC_SCHPO
          Length = 472

 Score =  154 bits (388), Expect = 7e-36
 Identities = 81/158 (51%), Positives = 113/158 (71%), Gaps = 3/158 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+  YQ+ VLSN+   A   + RGY+LVSGGTD HLVLV+L  KG+DG+RVE++LE V
Sbjct: 312 TPEFYQYQKDVLSNAKAMANAFITRGYKLVSGGTDTHLVLVDLTDKGVDGARVERILELV 371

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEA- 263
           +I++NKNTVPGD SA++P G+R+GTPA T+RGF E+DF +V E  D+ V++  K+   A 
Sbjct: 372 NISANKNTVPGDKSALIPRGLRLGTPACTTRGFDEKDFERVVELIDEVVSLTKKINEAAL 431

Query: 262 -QG-TKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQF 155
            +G +K +DF + +   S   SEIAKL+ EV  +A +F
Sbjct: 432 KEGKSKFRDFKAYVGDGSKF-SEIAKLKKEVITWAGKF 468

[220][TOP]
>UniRef100_P07511 Serine hydroxymethyltransferase, cytosolic n=1 Tax=Oryctolagus
           cuniculus RepID=GLYC_RABIT
          Length = 484

 Score =  154 bits (388), Expect = 7e-36
 Identities = 76/160 (47%), Positives = 105/160 (65%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ QV++N    +  L+E GY++V+GG+DNHL+LV+L+ KG DG R EKVLEA 
Sbjct: 321 TPEFKEYQRQVVANCRALSAALVELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEAC 380

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-A 263
            IA NKNT PGD SA+ P G+R+GTPALTSRG +E+DF KVA +  + + + ++++ +  
Sbjct: 381 SIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTVQIQDDTG 440

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   +      Q  +  LR EVE FA  FP  G
Sbjct: 441 PRATLKEFKEKLAGDEKHQRAVRALRQEVESFAALFPLPG 480

[221][TOP]
>UniRef100_Q2QT32 Serine hydroxymethyltransferase n=1 Tax=Oryza sativa Japonica Group
           RepID=Q2QT32_ORYSJ
          Length = 531

 Score =  153 bits (387), Expect = 1e-35
 Identities = 82/166 (49%), Positives = 112/166 (67%)
 Frame = -3

Query: 610 YKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIA 431
           +K+Y +QV +N+      LM +GY+LV+ GT+NHLVL +L+P G+ G++VEKV +   I 
Sbjct: 371 FKSYIKQVKANAVALGNHLMSKGYKLVTDGTENHLVLWDLRPLGLTGNKVEKVCDLCSIT 430

Query: 430 SNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTK 251
            NKN V GD SAM PGG+R+GTPA+TSRG VEEDF ++AE+  +AVTI L V+ E +G  
Sbjct: 431 LNKNAVFGDSSAMSPGGVRIGTPAMTSRGLVEEDFVQIAEFLHQAVTICLDVQKE-RGKL 489

Query: 250 LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           LK F   +E++  I+     LR EVE+FA  F   GF    MKYK+
Sbjct: 490 LKYFNEGLENNKDIED----LRAEVEKFATSFEMPGFRVSDMKYKD 531

[222][TOP]
>UniRef100_Q0INQ6 Serine hydroxymethyltransferase (Fragment) n=1 Tax=Oryza sativa
           Japonica Group RepID=Q0INQ6_ORYSJ
          Length = 462

 Score =  153 bits (387), Expect = 1e-35
 Identities = 82/166 (49%), Positives = 112/166 (67%)
 Frame = -3

Query: 610 YKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIA 431
           +K+Y +QV +N+      LM +GY+LV+ GT+NHLVL +L+P G+ G++VEKV +   I 
Sbjct: 302 FKSYIKQVKANAVALGNHLMSKGYKLVTDGTENHLVLWDLRPLGLTGNKVEKVCDLCSIT 361

Query: 430 SNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTK 251
            NKN V GD SAM PGG+R+GTPA+TSRG VEEDF ++AE+  +AVTI L V+ E +G  
Sbjct: 362 LNKNAVFGDSSAMSPGGVRIGTPAMTSRGLVEEDFVQIAEFLHQAVTICLDVQKE-RGKL 420

Query: 250 LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           LK F   +E++  I+     LR EVE+FA  F   GF    MKYK+
Sbjct: 421 LKYFNEGLENNKDIED----LRAEVEKFATSFEMPGFRVSDMKYKD 462

[223][TOP]
>UniRef100_C1E3R7 Serine hydroxymethyltransferase n=1 Tax=Micromonas sp. RCC299
           RepID=C1E3R7_9CHLO
          Length = 422

 Score =  153 bits (387), Expect = 1e-35
 Identities = 77/163 (47%), Positives = 112/163 (68%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E+K YQ+QV +N+   A  LM +GY+LV+ GTDNHLVL +L+P G+ GS++E + + +HI
Sbjct: 263 EFKRYQQQVKANARALASALMSKGYKLVTDGTDNHLVLWDLRPCGLTGSKMETICDMLHI 322

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
             NKN V GD SA+ PGG R+G PA+TSRG  E DF K+A++  KAV +AL+V++ + G 
Sbjct: 323 TLNKNAVFGDASALTPGGCRIGAPAMTSRGLKENDFEKIADFLHKAVELALEVQA-SHGK 381

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETM 125
            LKD+   +E +  + +    LR EVE FA+ FP  GF +E++
Sbjct: 382 MLKDWKLGLEGNPAVDT----LRAEVEAFAESFPMPGFTRESV 420

[224][TOP]
>UniRef100_A2ZJS7 Putative uncharacterized protein n=1 Tax=Oryza sativa Indica Group
           RepID=A2ZJS7_ORYSI
          Length = 294

 Score =  153 bits (387), Expect = 1e-35
 Identities = 82/166 (49%), Positives = 112/166 (67%)
 Frame = -3

Query: 610 YKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIA 431
           +K+Y +QV +N+      LM +GY+LV+ GT+NHLVL +L+P G+ G++VEKV +   I 
Sbjct: 134 FKSYIKQVKANAVALGNHLMSKGYKLVTDGTENHLVLWDLRPLGLTGNKVEKVCDLCSIT 193

Query: 430 SNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTK 251
            NKN V GD SAM PGG+R+GTPA+TSRG VEEDF ++AE+  +AVTI L V+ E +G  
Sbjct: 194 LNKNAVFGDSSAMSPGGVRIGTPAMTSRGLVEEDFVQIAEFLHQAVTICLDVQKE-RGKL 252

Query: 250 LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           LK F   +E++  I+     LR EVE+FA  F   GF    MKYK+
Sbjct: 253 LKYFNEGLENNKDIED----LRAEVEKFATSFEMPGFRVSDMKYKD 294

[225][TOP]
>UniRef100_Q7Q2F2 Serine hydroxymethyltransferase (Fragment) n=1 Tax=Anopheles
           gambiae RepID=Q7Q2F2_ANOGA
          Length = 475

 Score =  153 bits (387), Expect = 1e-35
 Identities = 73/158 (46%), Positives = 108/158 (68%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E++AYQEQV+ N+      L+E+GY + +GGTD HLVLV+L+P  I G+R E +LE + I
Sbjct: 316 EFRAYQEQVIKNARALCAGLLEKGYSVATGGTDVHLVLVDLRPVAITGARAEYILEEISI 375

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
           A NKNTVPGD SA+ P GIR+GTPALT+RG +E+D  +V E+ D+ + ++ ++ +   G 
Sbjct: 376 ACNKNTVPGDKSALNPSGIRLGTPALTTRGLLEKDMQQVVEFIDRGLRLSKEI-ANVSGP 434

Query: 253 KLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGF 140
           KL DF   +   ST   ++  LR EVE++++QF   G+
Sbjct: 435 KLSDFKRILHEDSTFSEKVNNLRKEVEQYSEQFLLPGY 472

[226][TOP]
>UniRef100_C1HCM1 Serine hydroxymethyltransferase n=1 Tax=Paracoccidioides
           brasiliensis Pb01 RepID=C1HCM1_PARBA
          Length = 535

 Score =  153 bits (387), Expect = 1e-35
 Identities = 87/171 (50%), Positives = 114/171 (66%), Gaps = 16/171 (9%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMER------GYELVSGGTDNHLVLVNLKPKGIDGSRVE 458
           T E+K YQ+ VL N+   A  L +       GY +VSGGTDNHLVLV+LK +G+DG+RVE
Sbjct: 357 TPEFKTYQQNVLENAKALADRLGKPTNSGGLGYNIVSGGTDNHLVLVDLKNRGVDGARVE 416

Query: 457 KVLEAVHIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALK 278
           +VLE   +ASNKNTVPGD SAM PGG+R+GTPA+TSRGF+ EDF +VA+  D+AVTI  K
Sbjct: 417 RVLELCAVASNKNTVPGDKSAMKPGGLRIGTPAMTSRGFLPEDFVRVADIVDRAVTITQK 476

Query: 277 V----KSEAQGTK------LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQF 155
           +    K++A+  K      +K F+  +     I  EI +LR EVEE+   F
Sbjct: 477 LDKTAKADAEAKKRKNPGSIKAFLEYLGEGEGI-PEILQLRQEVEEWVGTF 526

[227][TOP]
>UniRef100_C1H9H1 Serine hydroxymethyltransferase n=1 Tax=Paracoccidioides
           brasiliensis Pb01 RepID=C1H9H1_PARBA
          Length = 471

 Score =  153 bits (387), Expect = 1e-35
 Identities = 79/158 (50%), Positives = 107/158 (67%), Gaps = 2/158 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQEQVL N+        + GY+LVS GTD+H+VL++L PK +DG+RVE VLE +
Sbjct: 313 TPEFKQYQEQVLKNAKALEHEFKKLGYKLVSDGTDSHMVLLDLTPKALDGARVEAVLEQI 372

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-- 266
           +IA NKN++PGD SA+ P GIR+G PA+TSRG  EEDF ++A + DKA+ I   V+SE  
Sbjct: 373 NIACNKNSIPGDKSALSPCGIRIGAPAMTSRGMGEEDFKRIANFIDKAINICKSVQSELP 432

Query: 265 AQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 152
               KLKDF + + S +    EI  LR ++ E+A  FP
Sbjct: 433 KDANKLKDFKAKVASETV--PEILTLRKDIAEWASTFP 468

[228][TOP]
>UniRef100_A2YCP9 Serine hydroxymethyltransferase n=1 Tax=Oryza sativa Indica Group
           RepID=A2YCP9_ORYSI
          Length = 531

 Score =  153 bits (386), Expect = 1e-35
 Identities = 82/166 (49%), Positives = 112/166 (67%)
 Frame = -3

Query: 610 YKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIA 431
           +K+Y +QV +N+      LM +GY+LV+ GT+NHLVL +L+P G+ G++VEKV +   I 
Sbjct: 371 FKSYIKQVKANAVALGNHLMSKGYKLVTDGTENHLVLWDLRPLGLTGNKVEKVCDLCSIT 430

Query: 430 SNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTK 251
            NKN V GD SAM PGG+R+GTPA+TSRG VE+DF ++AE+  +AVTI L V+ E +G  
Sbjct: 431 LNKNAVFGDSSAMSPGGVRIGTPAMTSRGLVEKDFVQIAEFLHQAVTICLDVQKE-RGKL 489

Query: 250 LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           LK F   +E+S  I+     LR EVE+FA  F   GF    MKYK+
Sbjct: 490 LKYFNEGLENSKDIED----LRAEVEKFATSFEMPGFRVSDMKYKD 531

[229][TOP]
>UniRef100_B0XY66 Serine hydroxymethyltransferase n=2 Tax=Aspergillus fumigatus
           RepID=B0XY66_ASPFC
          Length = 471

 Score =  153 bits (386), Expect = 1e-35
 Identities = 77/158 (48%), Positives = 109/158 (68%), Gaps = 2/158 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E++ YQEQVL N+          G++LVS GTD+H+VL++L+PKG+DG+RVE VLE +
Sbjct: 313 TPEFRQYQEQVLKNAKALEVEFKALGHKLVSDGTDSHMVLLDLRPKGLDGARVEAVLEQI 372

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-- 266
           +IA NKN++PGD SA+ P GIR+GTPA+TSRG  EEDF +VA Y D+ + +   ++++  
Sbjct: 373 NIACNKNSIPGDKSALTPCGIRIGTPAMTSRGMSEEDFKRVARYIDQVINLCKSIQADLP 432

Query: 265 AQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 152
            +  KLKDF + + S S    EI  LR EV E+A  +P
Sbjct: 433 KEANKLKDFKAKVASGSV--PEILALRKEVAEWASTYP 468

[230][TOP]
>UniRef100_UPI00019834D0 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
           RepID=UPI00019834D0
          Length = 471

 Score =  152 bits (385), Expect = 2e-35
 Identities = 77/166 (46%), Positives = 114/166 (68%)
 Frame = -3

Query: 610 YKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIA 431
           +KAY +QV +N+      LM +GY+LV+GGT+NHLVL +L+P G+ G++VEK+ +  +I 
Sbjct: 311 FKAYAKQVKANAVALGNYLMSKGYKLVTGGTENHLVLWDLRPLGLTGNKVEKLCDLCNIT 370

Query: 430 SNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTK 251
            NKN V GD SA+ PGG+R+G PA+TSRG VE+DF ++AE+  +AVTI LK++ E  G  
Sbjct: 371 VNKNAVFGDSSALAPGGVRIGAPAMTSRGLVEKDFEQIAEFLHRAVTITLKIQKE-HGKL 429

Query: 250 LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           LKDF   + ++     +I +L+ +VE+F+  F   GF    MKYK+
Sbjct: 430 LKDFNKGLVNN----KDIEELKVDVEKFSASFEMPGFSVSEMKYKD 471

[231][TOP]
>UniRef100_A7Q734 Chromosome chr5 scaffold_58, whole genome shotgun sequence n=1
           Tax=Vitis vinifera RepID=A7Q734_VITVI
          Length = 243

 Score =  152 bits (385), Expect = 2e-35
 Identities = 77/166 (46%), Positives = 114/166 (68%)
 Frame = -3

Query: 610 YKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIA 431
           +KAY +QV +N+      LM +GY+LV+GGT+NHLVL +L+P G+ G++VEK+ +  +I 
Sbjct: 83  FKAYAKQVKANAVALGNYLMSKGYKLVTGGTENHLVLWDLRPLGLTGNKVEKLCDLCNIT 142

Query: 430 SNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTK 251
            NKN V GD SA+ PGG+R+G PA+TSRG VE+DF ++AE+  +AVTI LK++ E  G  
Sbjct: 143 VNKNAVFGDSSALAPGGVRIGAPAMTSRGLVEKDFEQIAEFLHRAVTITLKIQKE-HGKL 201

Query: 250 LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 113
           LKDF   + ++     +I +L+ +VE+F+  F   GF    MKYK+
Sbjct: 202 LKDFNKGLVNN----KDIEELKVDVEKFSASFEMPGFSVSEMKYKD 243

[232][TOP]
>UniRef100_C1GDE1 Serine hydroxymethyltransferase n=1 Tax=Paracoccidioides
           brasiliensis Pb18 RepID=C1GDE1_PARBD
          Length = 535

 Score =  152 bits (385), Expect = 2e-35
 Identities = 88/171 (51%), Positives = 113/171 (66%), Gaps = 16/171 (9%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMER------GYELVSGGTDNHLVLVNLKPKGIDGSRVE 458
           T E+K YQ+ VL N+   A  L +       GY +VSGGTDNHLVLV+LK +G+DG+RVE
Sbjct: 357 TPEFKTYQQNVLENAKALADRLGKPTNSGGLGYNIVSGGTDNHLVLVDLKNRGVDGARVE 416

Query: 457 KVLEAVHIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTI--- 287
           +VLE   +ASNKNTVPGD SAM PGG+R+GTPA+TSRGF+ EDF +VA+  D+AVTI   
Sbjct: 417 RVLELCAVASNKNTVPGDKSAMKPGGLRIGTPAMTSRGFLPEDFVRVADIVDRAVTITQK 476

Query: 286 ---ALKVKSEAQGTK----LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQF 155
              A K  +EA+  K    +K F+  +     I  EI +LR EVEE+   F
Sbjct: 477 LDKAAKANAEAKKRKNPGSVKAFLEYLGEGEGI-PEILQLRQEVEEWVGTF 526

[233][TOP]
>UniRef100_C0SAF1 Serine hydroxymethyltransferase n=1 Tax=Paracoccidioides
           brasiliensis Pb03 RepID=C0SAF1_PARBP
          Length = 533

 Score =  152 bits (385), Expect = 2e-35
 Identities = 88/171 (51%), Positives = 113/171 (66%), Gaps = 16/171 (9%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMER------GYELVSGGTDNHLVLVNLKPKGIDGSRVE 458
           T E+K YQ+ VL N+   A  L +       GY +VSGGTDNHLVLV+LK +G+DG+RVE
Sbjct: 357 TPEFKTYQQNVLENAKALADRLGKPTNSGGLGYNIVSGGTDNHLVLVDLKNRGVDGARVE 416

Query: 457 KVLEAVHIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTI--- 287
           +VLE   +ASNKNTVPGD SAM PGG+R+GTPA+TSRGF+ EDF +VA+  D+AVTI   
Sbjct: 417 RVLELCAVASNKNTVPGDKSAMKPGGLRIGTPAMTSRGFLPEDFVRVADIVDRAVTITQK 476

Query: 286 ---ALKVKSEAQGTK----LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQF 155
              A K  +EA+  K    +K F+  +     I  EI +LR EVEE+   F
Sbjct: 477 LDKAAKANAEAKKRKNPGSVKAFLEYLGEGEGI-PEILQLRQEVEEWVGTF 526

[234][TOP]
>UniRef100_B8M705 Serine hydroxymethyltransferase n=1 Tax=Talaromyces stipitatus ATCC
           10500 RepID=B8M705_TALSN
          Length = 471

 Score =  152 bits (385), Expect = 2e-35
 Identities = 78/158 (49%), Positives = 107/158 (67%), Gaps = 2/158 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E++ YQEQV+ N+        E GY+LV+ GTD+H+VLV+L+P G+DG+RVE VLE +
Sbjct: 313 TPEFRQYQEQVIKNAKALEVAFKEYGYKLVADGTDSHMVLVDLRPNGVDGARVEAVLEQI 372

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKS--E 266
           +IA NKN VPGD SA+ PGGIR+G PA+T+RG  EEDF +V  Y DKA+ I+ + ++   
Sbjct: 373 NIACNKNAVPGDKSALSPGGIRVGAPAMTTRGLGEEDFKRVVGYIDKAIKISKETQAGLP 432

Query: 265 AQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 152
            +  KLKDF + + S S    EI  LR E+  +A  FP
Sbjct: 433 KEANKLKDFKAKVASDSI--PEILSLRKEIAAWASTFP 468

[235][TOP]
>UniRef100_B6QQZ0 Serine hydroxymethyltransferase n=1 Tax=Penicillium marneffei ATCC
           18224 RepID=B6QQZ0_PENMQ
          Length = 471

 Score =  152 bits (385), Expect = 2e-35
 Identities = 80/158 (50%), Positives = 107/158 (67%), Gaps = 2/158 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E++ YQEQ + N+        E GY+LV+ GTD+H+VLV+L+P GIDG+RVE VLE +
Sbjct: 313 TPEFRQYQEQTIKNAKALEVAFKEYGYKLVADGTDSHMVLVDLRPNGIDGARVETVLEQI 372

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-- 266
           +IA NKN VPGD SA+ PGGIR+G PA+T+RG  EEDF +V  Y D+A+ I+  +++   
Sbjct: 373 NIACNKNAVPGDKSALSPGGIRVGAPAMTTRGLGEEDFKRVVGYIDQAIKISKSIQASLP 432

Query: 265 AQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 152
            +  KLKDF  A  SS TI  EI  LR E+  +A  FP
Sbjct: 433 KEANKLKDF-KAKASSETI-PEILNLRKEISAWASTFP 468

[236][TOP]
>UniRef100_B0D7Y2 Serine hydroxymethyltransferase n=1 Tax=Laccaria bicolor S238N-H82
           RepID=B0D7Y2_LACBS
          Length = 501

 Score =  152 bits (385), Expect = 2e-35
 Identities = 80/167 (47%), Positives = 110/167 (65%), Gaps = 3/167 (1%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHI 434
           E++AY +QV+SN+   A +L+E GY L +GGTDNHLVL +L+P G+ GS+VEKV + + I
Sbjct: 327 EFRAYAKQVISNAQTLASSLIEHGYRLQTGGTDNHLVLWDLRPIGLTGSKVEKVCDLMGI 386

Query: 433 ASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGT 254
             NKN V GD SA VPGGIR+GT ALTSR   E D  KVAE+  +AV ++L ++ EA   
Sbjct: 387 TINKNAVSGDASAQVPGGIRLGTSALTSRDMKEADIKKVAEFLHRAVQLSLLLQKEAGSK 446

Query: 253 KLKDFV---SAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMK 122
            LKDFV   +  E+     +++ +LR EV+ FA  FP  G +   +K
Sbjct: 447 LLKDFVRVATTQEAGKEGYAKVKELRDEVQSFASAFPLPGVDVSALK 493

[237][TOP]
>UniRef100_Q6C5P5 Serine hydroxymethyltransferase n=1 Tax=Yarrowia lipolytica
           RepID=Q6C5P5_YARLI
          Length = 471

 Score =  152 bits (384), Expect = 2e-35
 Identities = 75/155 (48%), Positives = 109/155 (70%), Gaps = 2/155 (1%)
 Frame = -3

Query: 610 YKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIA 431
           ++ YQEQVL N+        + GY LVSGGTD+H+VLV+L+ KGIDG+RVE V E ++IA
Sbjct: 316 FREYQEQVLKNAKALETEFNKLGYNLVSGGTDSHMVLVSLRDKGIDGARVETVCEQINIA 375

Query: 430 SNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKS--EAQG 257
            NKN++PGD SA+VPGG+R+G PA+++RGF EEDF K+A Y  +AV +A++++     + 
Sbjct: 376 LNKNSIPGDKSALVPGGVRIGAPAMSTRGFGEEDFKKIANYISQAVDLAIEIQQGLPKEA 435

Query: 256 TKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 152
            KLKDF +A ++      +I  L+ E+  +A QFP
Sbjct: 436 NKLKDFKAAAQAGG--NPKIEALKTEISNWAGQFP 468

[238][TOP]
>UniRef100_Q5A8J8 Serine hydroxymethyltransferase n=1 Tax=Candida albicans
           RepID=Q5A8J8_CANAL
          Length = 470

 Score =  152 bits (384), Expect = 2e-35
 Identities = 78/158 (49%), Positives = 108/158 (68%), Gaps = 2/158 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQEQVL N+        ++GY+LVS GTD+H+VLV+LK K IDG+RVE V E +
Sbjct: 313 TPEFKEYQEQVLKNAKALESEFTKKGYKLVSDGTDSHMVLVSLKDKQIDGARVETVCEKI 372

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-- 266
           +IA NKN++PGD SA+VPGG+R+G PA+T+RG  EEDF K+  Y D AV  A +V+S+  
Sbjct: 373 NIALNKNSIPGDKSALVPGGVRIGAPAMTTRGLGEEDFKKIVSYIDFAVNYAKEVQSQLP 432

Query: 265 AQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 152
               KLKDF +A+   S    ++  +R E+ ++A  FP
Sbjct: 433 KDANKLKDFKNAVSGDS---EKLKAVRDEIYQWAGSFP 467

[239][TOP]
>UniRef100_A1D7C1 Serine hydroxymethyltransferase n=1 Tax=Neosartorya fischeri NRRL
           181 RepID=A1D7C1_NEOFI
          Length = 471

 Score =  152 bits (384), Expect = 2e-35
 Identities = 76/158 (48%), Positives = 109/158 (68%), Gaps = 2/158 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E++ YQEQV+ N+          G++LVS GTD+H+VL++L+PKG+DG+RVE VLE +
Sbjct: 313 TPEFRQYQEQVIKNAKALEVEFKALGHKLVSDGTDSHMVLLDLRPKGLDGARVEAVLEQI 372

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-- 266
           +IA NKN++PGD SA+ P GIR+GTPA+TSRG  EEDF +VA Y D+ + +   ++++  
Sbjct: 373 NIACNKNSIPGDKSALTPCGIRIGTPAMTSRGMSEEDFKRVARYIDQVINLCKSIQADLP 432

Query: 265 AQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 152
            +  KLKDF + + S S    EI  LR EV E+A  +P
Sbjct: 433 KEANKLKDFKAKVASDSV--PEILALRKEVAEWASTYP 468

[240][TOP]
>UniRef100_Q5RFK5 Serine hydroxymethyltransferase, cytosolic n=1 Tax=Pongo abelii
           RepID=GLYC_PONAB
          Length = 483

 Score =  152 bits (384), Expect = 2e-35
 Identities = 77/160 (48%), Positives = 107/160 (66%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ QV++N    ++ L E GY++V+GG+DNHL+LV+L+ KG DG R EKVLEA 
Sbjct: 321 TLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEAC 380

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-A 263
            IA NKNT PGD SA+ P G+R+GTPALTSRG +E+DF KVA +  + + + L+++S+  
Sbjct: 381 SIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTG 440

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   + +    Q  +  LR +VE FA  FP  G
Sbjct: 441 VRATLKEFKERL-AGDKYQGAVQALREKVESFASLFPLPG 479

[241][TOP]
>UniRef100_O13426 Serine hydroxymethyltransferase, cytosolic n=1 Tax=Candida albicans
           RepID=GLYC_CANAL
          Length = 470

 Score =  152 bits (384), Expect = 2e-35
 Identities = 78/158 (49%), Positives = 108/158 (68%), Gaps = 2/158 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQEQVL N+        ++GY+LVS GTD+H+VLV+LK K IDG+RVE V E +
Sbjct: 313 TPEFKEYQEQVLKNAKALESEFTKKGYKLVSDGTDSHMVLVSLKDKQIDGARVETVCEKI 372

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-- 266
           +IA NKN++PGD SA+VPGG+R+G PA+T+RG  EEDF K+  Y D AV  A +V+S+  
Sbjct: 373 NIALNKNSIPGDKSALVPGGVRIGAPAMTTRGLGEEDFKKIVSYIDFAVNYAKEVQSQLP 432

Query: 265 AQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 152
               KLKDF +A+   S    ++  +R E+ ++A  FP
Sbjct: 433 KDANKLKDFKNAVSGDS---EKLKAVRDEIYQWAGSFP 467

[242][TOP]
>UniRef100_C8V028 Serine hydroxymethyltransferase (Eurofung) n=1 Tax=Aspergillus
           nidulans FGSC A4 RepID=C8V028_EMENI
          Length = 600

 Score =  152 bits (383), Expect = 3e-35
 Identities = 86/171 (50%), Positives = 116/171 (67%), Gaps = 16/171 (9%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMER------GYELVSGGTDNHLVLVNLKPKGIDGSRVE 458
           ++E+K YQE VL+N+   A+ L         GY +VSGGTDNHLVLV+LK +G+DG+RVE
Sbjct: 424 STEFKTYQETVLANAKSLAERLGGSTSSGGLGYNIVSGGTDNHLVLVDLKNRGVDGARVE 483

Query: 457 KVLEAVHIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALK 278
           +VLE   +ASNKNTVPGD SA+ PGG+R+GTPA+T+RGF  EDF +VA+  D+AVTI  K
Sbjct: 484 RVLELCGVASNKNTVPGDRSALKPGGLRLGTPAMTTRGFQPEDFRRVADIVDRAVTITQK 543

Query: 277 VKSEA------QGTK----LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQF 155
           +   A      +G K    +K F+  + +   I SEI +LR EVE++A  F
Sbjct: 544 LDKSAKESAASKGVKNPNTVKAFLEYVGNGEEI-SEIVQLRQEVEDWAGTF 593

[243][TOP]
>UniRef100_C4JEX8 Serine hydroxymethyltransferase n=1 Tax=Uncinocarpus reesii 1704
           RepID=C4JEX8_UNCRE
          Length = 481

 Score =  152 bits (383), Expect = 3e-35
 Identities = 88/169 (52%), Positives = 111/169 (65%), Gaps = 16/169 (9%)
 Frame = -3

Query: 613 EYKAYQEQVLSNSAKFAQTLMER------GYELVSGGTDNHLVLVNLKPKGIDGSRVEKV 452
           E+K YQ+ VL N+   A  L         GY +VSGGTDNHLVLV+LK +G+DG+RVE+V
Sbjct: 307 EFKTYQQNVLENAKALAGRLGNSTNSGGLGYNIVSGGTDNHLVLVDLKNRGVDGARVERV 366

Query: 451 LEAVHIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKV- 275
           LE   +ASNKNTVPGD SAM PGG+RMGTPA+TSRGF  EDF++VA+  D+AV I  K+ 
Sbjct: 367 LELCGVASNKNTVPGDKSAMKPGGLRMGTPAMTSRGFGPEDFSRVADIVDRAVIITQKLD 426

Query: 274 ---KSEAQG------TKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQF 155
              K+EA+       T LK F   +     I SEI +LR EVE++   F
Sbjct: 427 KAAKAEAESKNRKNPTSLKAFFEYLGEGEEI-SEIVQLRKEVEDWVGTF 474

[244][TOP]
>UniRef100_B9WJ77 Serine hydroxymethyltransferase n=1 Tax=Candida dubliniensis CD36
           RepID=B9WJ77_CANDC
          Length = 470

 Score =  152 bits (383), Expect = 3e-35
 Identities = 78/158 (49%), Positives = 107/158 (67%), Gaps = 2/158 (1%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQEQVL N+         +GY+LVS GTD+H+VLV+LK K IDG+RVE V E +
Sbjct: 313 TPEFKEYQEQVLKNAKALESEFKNKGYKLVSDGTDSHMVLVSLKDKQIDGARVETVCEKI 372

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-- 266
           +IA NKN++PGD SA+VPGG+R+G PA+T+RG  EEDF K+  Y D AV  A +V+S+  
Sbjct: 373 NIALNKNSIPGDKSALVPGGVRIGAPAMTTRGLGEEDFKKIVSYIDFAVNYAKEVQSQLP 432

Query: 265 AQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 152
               KLKDF +A+   S    ++  +R E+ ++A  FP
Sbjct: 433 KDANKLKDFKNAVSGDS---EKLKAVRDEIYQWAGSFP 467

[245][TOP]
>UniRef100_C5Y297 Serine hydroxymethyltransferase n=1 Tax=Sorghum bicolor
           RepID=C5Y297_SORBI
          Length = 471

 Score =  151 bits (382), Expect = 4e-35
 Identities = 77/168 (45%), Positives = 113/168 (67%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  +KAY +QV +N+      LM +GY++V+ GT+NHLVL +L+P G+ G++VEK+ +  
Sbjct: 308 TPGFKAYAKQVKANAVAIGNYLMSKGYKMVTDGTENHLVLWDLRPLGLTGNKVEKLCDLC 367

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
           HI  NKN V GD SA+ PGG+R+G PA+TSRG VE+DF ++ E+  +AVTI L ++ E  
Sbjct: 368 HITLNKNAVFGDSSALAPGGVRIGAPAMTSRGLVEKDFEQIGEFLHQAVTICLNIQKE-Y 426

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYK 116
           G  LKDF   + ++  I++    L+ +VE+FA  F   GF  E+MKYK
Sbjct: 427 GKLLKDFNKGLLNNKDIEN----LKTQVEKFADSFDMPGFTLESMKYK 470

[246][TOP]
>UniRef100_C6HT53 Serine hydroxymethyltransferase n=1 Tax=Ajellomyces capsulatus H143
           RepID=C6HT53_AJECH
          Length = 590

 Score =  151 bits (382), Expect = 4e-35
 Identities = 87/171 (50%), Positives = 112/171 (65%), Gaps = 16/171 (9%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMER------GYELVSGGTDNHLVLVNLKPKGIDGSRVE 458
           T E+K YQE VL N+   A  L +       GY +VSGGTDNHLVLV+LK +G+DG+RVE
Sbjct: 412 TPEFKTYQETVLENAKALADRLGKPTNSGGLGYNIVSGGTDNHLVLVDLKNRGVDGARVE 471

Query: 457 KVLEAVHIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALK 278
           +VLE   +ASNKNTVPGD SAM PGG+R+GTPA+TSRGF  EDF +VA+  D+AVTI  K
Sbjct: 472 RVLELCGVASNKNTVPGDKSAMKPGGLRIGTPAMTSRGFGPEDFVRVADIVDRAVTITQK 531

Query: 277 V----KSEAQGTK------LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQF 155
           +    K++A+  K      +K F+  +     I  EI  LR EVE++   F
Sbjct: 532 LDKTAKADAEAKKKKNPGSVKAFLEYLGEGQAI-PEITTLRQEVEDWVGTF 581

[247][TOP]
>UniRef100_C0NMB4 Serine hydroxymethyltransferase n=1 Tax=Ajellomyces capsulatus
           G186AR RepID=C0NMB4_AJECG
          Length = 530

 Score =  151 bits (382), Expect = 4e-35
 Identities = 87/171 (50%), Positives = 112/171 (65%), Gaps = 16/171 (9%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMER------GYELVSGGTDNHLVLVNLKPKGIDGSRVE 458
           T E+K YQE VL N+   A  L +       GY +VSGGTDNHLVLV+LK +G+DG+RVE
Sbjct: 352 TPEFKTYQETVLENAKALADRLGKPTNSGGLGYNIVSGGTDNHLVLVDLKNRGVDGARVE 411

Query: 457 KVLEAVHIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALK 278
           +VLE   +ASNKNTVPGD SAM PGG+R+GTPA+TSRGF  EDF +VA+  D+AVTI  K
Sbjct: 412 RVLELCGVASNKNTVPGDKSAMKPGGLRIGTPAMTSRGFGPEDFVRVADIVDRAVTITQK 471

Query: 277 V----KSEAQGTK------LKDFVSAMESSSTIQSEIAKLRHEVEEFAKQF 155
           +    K++A+  K      +K F+  +     I  EI  LR EVE++   F
Sbjct: 472 LDKTAKADAEAKKKKNPGSVKAFLEYLGEGQAI-PEITTLRQEVEDWVGTF 521

[248][TOP]
>UniRef100_UPI0000DD9C21 Os11g0455800 n=1 Tax=Oryza sativa Japonica Group
           RepID=UPI0000DD9C21
          Length = 471

 Score =  151 bits (381), Expect = 5e-35
 Identities = 77/168 (45%), Positives = 114/168 (67%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  +KAY +QV +N+    + LM +GY++V+ GT+NHLVL +L+P G+ G++VEK+ +  
Sbjct: 308 TPGFKAYAKQVKANAVAIGKYLMSKGYKMVTDGTENHLVLWDLRPLGLTGNKVEKMCDLC 367

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I  NKN V GD SA+ PGG+R+GTPA+TSRG VE+DF ++ E+  +AVTI L ++ E  
Sbjct: 368 SITLNKNAVFGDSSALAPGGVRIGTPAMTSRGLVEKDFEQIGEFLHQAVTICLNIQKE-H 426

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYK 116
           G  LKDF   + ++  I++    L+ EVE+FA  F   GF  ++MKYK
Sbjct: 427 GKLLKDFSKGLVNNKDIEN----LKLEVEKFATSFDMPGFTLDSMKYK 470

[249][TOP]
>UniRef100_UPI0000D9A0B5 PREDICTED: similar to serine hydroxymethyltransferase 1 (soluble)
           isoform 1 n=1 Tax=Macaca mulatta RepID=UPI0000D9A0B5
          Length = 282

 Score =  151 bits (381), Expect = 5e-35
 Identities = 77/160 (48%), Positives = 107/160 (66%), Gaps = 1/160 (0%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T E+K YQ QV++N    ++ LME GY++V+GG+ NHL+LV+L+ KG DG R EKVLEA 
Sbjct: 120 TLEFKVYQHQVVANCRALSEALMELGYKIVTGGSHNHLILVDLRSKGTDGGRAEKVLEAC 179

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE-A 263
            IA NKNT PGD SA+ P G+ +GTPALTSRG +E+DF KVA++  + + + L+++S+  
Sbjct: 180 SIACNKNTCPGDRSALRPSGLWLGTPALTSRGLLEKDFQKVAQFIHRGIELTLQIQSDIG 239

Query: 262 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIG 143
               LK+F   + +    Q  +  LR EVE FA  FP  G
Sbjct: 240 VRATLKEFKERL-AGDKYQGAVQALREEVESFASLFPLPG 278

[250][TOP]
>UniRef100_Q0ISV6 Serine hydroxymethyltransferase (Fragment) n=1 Tax=Oryza sativa
           Japonica Group RepID=Q0ISV6_ORYSJ
          Length = 497

 Score =  151 bits (381), Expect = 5e-35
 Identities = 77/168 (45%), Positives = 114/168 (67%)
 Frame = -3

Query: 619 TSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAV 440
           T  +KAY +QV +N+    + LM +GY++V+ GT+NHLVL +L+P G+ G++VEK+ +  
Sbjct: 334 TPGFKAYAKQVKANAVAIGKYLMSKGYKMVTDGTENHLVLWDLRPLGLTGNKVEKMCDLC 393

Query: 439 HIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQ 260
            I  NKN V GD SA+ PGG+R+GTPA+TSRG VE+DF ++ E+  +AVTI L ++ E  
Sbjct: 394 SITLNKNAVFGDSSALAPGGVRIGTPAMTSRGLVEKDFEQIGEFLHQAVTICLNIQKE-H 452

Query: 259 GTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYK 116
           G  LKDF   + ++  I++    L+ EVE+FA  F   GF  ++MKYK
Sbjct: 453 GKLLKDFSKGLVNNKDIEN----LKLEVEKFATSFDMPGFTLDSMKYK 496