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[1][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 264 bits (674), Expect = 3e-69
Identities = 125/125 (100%), Positives = 125/125 (100%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA
Sbjct: 437 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 496
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP
Sbjct: 497 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 556
Query: 17 EADPS 3
EADPS
Sbjct: 557 EADPS 561
[2][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=B9DHL6_ARATH
Length = 402
Score = 231 bits (588), Expect = 3e-59
Identities = 106/125 (84%), Positives = 113/125 (90%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQPSVNA +SDSP +GWGGP GYVYQKAYLEFFCSK+KLD +VEK KA PSITYMA
Sbjct: 247 LTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMA 306
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK E WVSNT ++DVNAVTWGVFPAKE+IQPTIVDPASF VWKDEAFE WSRSWANLYP
Sbjct: 307 VNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYP 366
Query: 17 EADPS 3
E DPS
Sbjct: 367 EDDPS 371
[3][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 231 bits (588), Expect = 3e-59
Identities = 106/125 (84%), Positives = 113/125 (90%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQPSVNA +SDSP +GWGGP GYVYQKAYLEFFCSK+KLD +VEK KA PSITYMA
Sbjct: 437 LTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMA 496
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK E WVSNT ++DVNAVTWGVFPAKE+IQPTIVDPASF VWKDEAFE WSRSWANLYP
Sbjct: 497 VNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYP 556
Query: 17 EADPS 3
E DPS
Sbjct: 557 EDDPS 561
[4][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 225 bits (574), Expect = 1e-57
Identities = 101/125 (80%), Positives = 113/125 (90%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VNAE+SDSP+VGWGGP GYVYQKAYLEFFCSKEKL+A+VE+CKA P +TYMA
Sbjct: 451 LTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYLEFFCSKEKLNALVERCKAFPLVTYMA 510
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VN+G W+SN A DVNAVTWGVFPAKEIIQPT+VDP SF+VWKDEAFE WSR WA+LYP
Sbjct: 511 VNRGGSWISNVALTDVNAVTWGVFPAKEIIQPTVVDPTSFSVWKDEAFEIWSRGWASLYP 570
Query: 17 EADPS 3
E DPS
Sbjct: 571 EGDPS 575
[5][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 219 bits (559), Expect = 6e-56
Identities = 97/125 (77%), Positives = 111/125 (88%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN E+SDSP+VGWGGP GYVYQKAYLEFFCSK+KL+A+V+KCK+ P +TY+A
Sbjct: 448 LTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYLEFFCSKDKLNALVDKCKSFPFVTYIA 507
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNKG W+SN A DVNAVTWGVFP KEIIQPT+VDP SF+VWKDEAFE WSR WA+LYP
Sbjct: 508 VNKGGSWISNVALTDVNAVTWGVFPGKEIIQPTVVDPTSFSVWKDEAFEIWSRGWASLYP 567
Query: 17 EADPS 3
E DPS
Sbjct: 568 EGDPS 572
[6][TOP]
>UniRef100_A9P8D1 Putative uncharacterized protein n=1 Tax=Populus trichocarpa
RepID=A9P8D1_POPTR
Length = 224
Score = 219 bits (559), Expect = 6e-56
Identities = 97/125 (77%), Positives = 111/125 (88%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN E+SDSP+VGWGGP GYVYQKAYLEFFCSK+KL+A+V+KCK+ P +TY+A
Sbjct: 67 LTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYLEFFCSKDKLNALVDKCKSFPFVTYIA 126
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNKG W+SN A DVNAVTWGVFP KEIIQPT+VDP SF+VWKDEAFE WSR WA+LYP
Sbjct: 127 VNKGGSWISNVALTDVNAVTWGVFPGKEIIQPTVVDPTSFSVWKDEAFEIWSRGWASLYP 186
Query: 17 EADPS 3
E DPS
Sbjct: 187 EGDPS 191
[7][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 213 bits (543), Expect = 4e-54
Identities = 95/125 (76%), Positives = 111/125 (88%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN E+SDSP+VGWGGP GYVYQKAY+EFFCS +KL A++EKCKALP +TYMA
Sbjct: 452 LTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYIEFFCSTDKLQALLEKCKALPQLTYMA 511
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VN+G +SN Q DVNAVTWGVFP K+IIQPT+VDPASF+VWKDEAFE W+R WA+LYP
Sbjct: 512 VNRGGTLLSNVGQNDVNAVTWGVFPGKQIIQPTVVDPASFSVWKDEAFEIWTRGWASLYP 571
Query: 17 EADPS 3
E+DPS
Sbjct: 572 ESDPS 576
[8][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 208 bits (529), Expect = 2e-52
Identities = 95/125 (76%), Positives = 108/125 (86%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN E+SDS +VGWGGP GYVYQKAYLEFFCS+EKL+A+V+KCK PS+TYMA
Sbjct: 437 LTINSQPAVNGEKSDSLSVGWGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHPSLTYMA 496
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK W+SN +VNAVTWGVFPA+EIIQPT+VDP+SF VWKDEAFE WSR WA LYP
Sbjct: 497 VNKEGTWMSNVGPGEVNAVTWGVFPAREIIQPTVVDPSSFMVWKDEAFEIWSRGWALLYP 556
Query: 17 EADPS 3
E DPS
Sbjct: 557 EDDPS 561
[9][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 205 bits (521), Expect = 1e-51
Identities = 94/125 (75%), Positives = 107/125 (85%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN E+SDS +VGWGGP GYVYQKAYLEFFCS+EKL+A+V+KCK S+TYMA
Sbjct: 437 LTINSQPAVNGEKSDSLSVGWGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHTSLTYMA 496
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK W+SN +VNAVTWGVFPA+EIIQPT+VDP+SF VWKDEAFE WSR WA LYP
Sbjct: 497 VNKEGTWMSNVGPGEVNAVTWGVFPAREIIQPTVVDPSSFMVWKDEAFEIWSRGWALLYP 556
Query: 17 EADPS 3
E DPS
Sbjct: 557 EDDPS 561
[10][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 205 bits (521), Expect = 1e-51
Identities = 94/125 (75%), Positives = 107/125 (85%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN E+SDS +VGWGGP GYVYQKAYLEFFCS+EKL+A+V+KCK S+TYMA
Sbjct: 430 LTINSQPAVNGEKSDSLSVGWGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHTSLTYMA 489
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK W+SN +VNAVTWGVFPA+EIIQPT+VDP+SF VWKDEAFE WSR WA LYP
Sbjct: 490 VNKEGTWMSNVGPGEVNAVTWGVFPAREIIQPTVVDPSSFMVWKDEAFEIWSRGWALLYP 549
Query: 17 EADPS 3
E DPS
Sbjct: 550 EDDPS 554
[11][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 201 bits (512), Expect = 2e-50
Identities = 94/125 (75%), Positives = 105/125 (84%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN E+SDSPTVGWGGP GYVYQKAYLEFFC+KEKLD ++EK KA PS+TY+A
Sbjct: 437 LTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKAFPSLTYIA 496
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK + SN A VNAVTWGVFP KEIIQPT+VDPASF VWKDEAFE W+R WA L+P
Sbjct: 497 VNKDGESFSNIAPNAVNAVTWGVFPGKEIIQPTVVDPASFMVWKDEAFEIWTRGWACLFP 556
Query: 17 EADPS 3
E D S
Sbjct: 557 EGDSS 561
[12][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 195 bits (495), Expect = 2e-48
Identities = 90/125 (72%), Positives = 103/125 (82%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN E+SDSPTVGWGGP GYVYQKAYLEFFC+KEKLD ++EK KA PS+TY+A
Sbjct: 437 LTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKAFPSLTYIA 496
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK + SN + VNAVTWGVFP KEIIQPT+VD ASF VWKDEAFE W+R W ++P
Sbjct: 497 VNKDGETFSNISPNAVNAVTWGVFPGKEIIQPTVVDHASFMVWKDEAFEIWTRGWGCMFP 556
Query: 17 EADPS 3
E D S
Sbjct: 557 EGDSS 561
[13][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 194 bits (492), Expect = 3e-48
Identities = 91/125 (72%), Positives = 102/125 (81%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN ERSDS +VGWGGP GYVYQKAYLEFFCSKEKLD ++EK KA PS+TY+A
Sbjct: 437 LTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIA 496
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK + SN VNAVTWGVFP KEI+QPT+VD ASF VWKDEAFE WS+ WA L+P
Sbjct: 497 VNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWKDEAFEIWSKGWACLFP 556
Query: 17 EADPS 3
E D S
Sbjct: 557 EGDSS 561
[14][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 194 bits (492), Expect = 3e-48
Identities = 86/125 (68%), Positives = 102/125 (81%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN E+SDSP++GWGG GYVYQKAY+EFFCS EKL+ +VEK K LP +TY+A
Sbjct: 437 LTINSQPAVNGEKSDSPSIGWGGAAGYVYQKAYVEFFCSPEKLNELVEKAKNLPFVTYIA 496
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK +N DVNAVTWGVFPAKE+IQPT+VDP SF VWKDEAF+ W + WA+LYP
Sbjct: 497 VNKKGATAANIGPTDVNAVTWGVFPAKEVIQPTVVDPVSFMVWKDEAFQAWEQEWASLYP 556
Query: 17 EADPS 3
+ DPS
Sbjct: 557 DGDPS 561
[15][TOP]
>UniRef100_A6N158 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Oryza sativa
Indica Group RepID=A6N158_ORYSI
Length = 237
Score = 194 bits (492), Expect = 3e-48
Identities = 91/125 (72%), Positives = 102/125 (81%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN ERSDS +VGWGGP GYVYQKAYLEFFCSKEKLD ++EK KA PS+TY+A
Sbjct: 80 LTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIA 139
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK + SN VNAVTWGVFP KEI+QPT+VD ASF VWKDEAFE WS+ WA L+P
Sbjct: 140 VNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWKDEAFEIWSKGWACLFP 199
Query: 17 EADPS 3
E D S
Sbjct: 200 EGDSS 204
[16][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 194 bits (492), Expect = 3e-48
Identities = 91/125 (72%), Positives = 102/125 (81%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN ERSDS +VGWGGP GYVYQKAYLEFFCSKEKLD ++EK KA PS+TY+A
Sbjct: 437 LTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIA 496
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK + SN VNAVTWGVFP KEI+QPT+VD ASF VWKDEAFE WS+ WA L+P
Sbjct: 497 VNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWKDEAFEIWSKGWACLFP 556
Query: 17 EADPS 3
E D S
Sbjct: 557 EGDSS 561
[17][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 193 bits (491), Expect = 4e-48
Identities = 88/125 (70%), Positives = 101/125 (80%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN E+SDSP+VGWGGP GYVYQKAY+EFFCS EKL AV+EK K PS+TY+A
Sbjct: 437 LTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYVEFFCSPEKLQAVIEKAKTSPSLTYIA 496
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VN + SN VNAVTWGVFPAKE+IQPT+VDP SF VWKDEAF+ W + WA+LYP
Sbjct: 497 VNAKGETKSNVGPTSVNAVTWGVFPAKEVIQPTVVDPVSFMVWKDEAFQAWDQEWASLYP 556
Query: 17 EADPS 3
E D S
Sbjct: 557 EDDAS 561
[18][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 193 bits (491), Expect = 4e-48
Identities = 90/125 (72%), Positives = 104/125 (83%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VNAE+S+SP+VGWGGP GYVYQKAY+EFFC+KEKL ++EK KA PS+TY+A
Sbjct: 425 LTINSQPAVNAEKSESPSVGWGGPGGYVYQKAYVEFFCAKEKLGQLIEKSKAFPSLTYIA 484
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK + +SN VNAVTWGVFP KEIIQPT+VD ASF VWKDEAFE WSR WA L+P
Sbjct: 485 VNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRGWACLFP 544
Query: 17 EADPS 3
E D S
Sbjct: 545 EGDSS 549
[19][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 187 bits (475), Expect = 3e-46
Identities = 87/125 (69%), Positives = 100/125 (80%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN E+SDSP+VGWGGP GYVYQKAY+EFFCS EKL AV+EK K+ PS+T++A
Sbjct: 437 LTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYVEFFCSPEKLQAVIEKAKSNPSLTFIA 496
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VN + SN VNAVTWGVFPAKE+IQPT+VDP SF VWKDEAF+TW WA LY
Sbjct: 497 VNAKGETQSNIGPNCVNAVTWGVFPAKEVIQPTVVDPVSFMVWKDEAFQTWDHEWAALYS 556
Query: 17 EADPS 3
E D S
Sbjct: 557 EEDSS 561
[20][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 146 bits (368), Expect = 8e-34
Identities = 72/126 (57%), Positives = 84/126 (66%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VNA S GWGGP GYVYQKAYLEFF S E+ ++E P I Y A
Sbjct: 464 LTINSQPNVNALPSTHEVFGWGGPNGYVYQKAYLEFFISAERFKTLLEVLPNFPMINYHA 523
Query: 197 VNKGEQW-VSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
++ E VSN+ AVTWGVFP +EI+QPT+VDP SF+ WKDEAF W+ WANLY
Sbjct: 524 LDLSESINVSNSDHHQPIAVTWGVFPGREILQPTVVDPTSFSYWKDEAFALWTNQWANLY 583
Query: 20 PEADPS 3
PE S
Sbjct: 584 PEESKS 589
[21][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 145 bits (365), Expect = 2e-33
Identities = 70/126 (55%), Positives = 83/126 (65%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKAL-PSITYM 201
LTINSQP+VN + S P VGWG GYV+QKAYLEFF S E + A+++ K P + Y
Sbjct: 474 LTINSQPNVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEMVSALIKVLKRYEPRVNYH 533
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
VN Q ++N A NAVTWG+FP +EIIQPT+VDP SF WKDEAF W WA LY
Sbjct: 534 IVNVHGQNITNAADLQPNAVTWGIFPGREIIQPTVVDPVSFVYWKDEAFALWIEQWAKLY 593
Query: 20 PEADPS 3
E PS
Sbjct: 594 EEESPS 599
[22][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 144 bits (362), Expect = 4e-33
Identities = 71/121 (58%), Positives = 77/121 (63%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP VN SD GWGGP GYVY KAY+EFFCS E + K A PSITY+A
Sbjct: 438 LTINSQPRVNGVASDDAVHGWGGPGGYVYGKAYVEFFCSPEAWATLRAKLDAAPSITYLA 497
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
N A VNAVTWGVFP KE+IQPT+V SF VWKDEAFE W+ W LY
Sbjct: 498 TTAAGSPAGNMAPDAVNAVTWGVFPGKEVIQPTVVCAPSFAVWKDEAFELWTSEWGALYE 557
Query: 17 E 15
E
Sbjct: 558 E 558
[23][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 143 bits (360), Expect = 7e-33
Identities = 69/126 (54%), Positives = 83/126 (65%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKAL-PSITYM 201
LTINSQP+VN + S P VGWG GYV+QKAYLEFF S E + A+++ K P + Y
Sbjct: 474 LTINSQPNVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEMVTALIKVLKRYEPRVNYH 533
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
VN Q ++N A +AVTWG+FP +EIIQPT+VDP SF WKDEAF W WA LY
Sbjct: 534 IVNVHGQNITNAADLQPSAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLY 593
Query: 20 PEADPS 3
E PS
Sbjct: 594 EEESPS 599
[24][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 142 bits (358), Expect = 1e-32
Identities = 72/125 (57%), Positives = 83/125 (66%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+V+ RSD GWG P GYVYQKAYLEFF S + L ++ + + P ITY A
Sbjct: 432 LTINSQPAVDGVRSDDKVHGWGPPGGYVYQKAYLEFFVSPDLLSPLIRRIEKDPRITYYA 491
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK +NT NAVTWGVFP KEI+QPTIV+ SF WKDEAFE WA+LYP
Sbjct: 492 VNKQGDLRTNTHSESPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFEL-GLQWAHLYP 550
Query: 17 EADPS 3
PS
Sbjct: 551 AESPS 555
[25][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 140 bits (354), Expect = 3e-32
Identities = 68/126 (53%), Positives = 82/126 (65%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VNA S P VGWG P GYV+QKAYLEFF S+E + A+ + P++ Y
Sbjct: 469 LTINSQPNVNAAPSTDPVVGWGTPGGYVFQKAYLEFFTSRENVQALFKVLPKYPNVNYHI 528
Query: 197 VN-KGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
+ +G+ +N Q AVTWGVFP KEIIQPT+VDP SF WKDEAF W+ W LY
Sbjct: 529 IKFEGDDDYTNCDQQQPIAVTWGVFPGKEIIQPTVVDPVSFKFWKDEAFTLWTEYWGQLY 588
Query: 20 PEADPS 3
E S
Sbjct: 589 AEDSKS 594
[26][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 139 bits (351), Expect = 8e-32
Identities = 65/126 (51%), Positives = 84/126 (66%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++NA+ S P VGWG GYV+QKAYLEFF S+E ++A+++ K + Y
Sbjct: 520 LTINSQPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYH 579
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
V+ + ++N + NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY
Sbjct: 580 IVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFAPWIEQWGKLY 639
Query: 20 PEADPS 3
E PS
Sbjct: 640 EEESPS 645
[27][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 139 bits (351), Expect = 8e-32
Identities = 65/126 (51%), Positives = 84/126 (66%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++NA+ S P VGWG GYV+QKAYLEFF S+E ++A+++ K + Y
Sbjct: 520 LTINSQPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYH 579
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
V+ + ++N + NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY
Sbjct: 580 IVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLY 639
Query: 20 PEADPS 3
E PS
Sbjct: 640 EEESPS 645
[28][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 139 bits (351), Expect = 8e-32
Identities = 65/126 (51%), Positives = 84/126 (66%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++NA+ S P VGWG GYV+QKAYLEFF S+E ++A+++ K + Y
Sbjct: 520 LTINSQPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYH 579
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
V+ + ++N + NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY
Sbjct: 580 IVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLY 639
Query: 20 PEADPS 3
E PS
Sbjct: 640 EEESPS 645
[29][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 139 bits (351), Expect = 8e-32
Identities = 65/126 (51%), Positives = 83/126 (65%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
L+INSQPSVNA S P +GWGG GY+YQKAYLEFF S E + ++++ K P + Y
Sbjct: 425 LSINSQPSVNAASSTDPLLGWGGEGGYIYQKAYLEFFASPEVVYILLQELKNYPQVNYHV 484
Query: 197 VNKGEQW-VSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
VN + ++N AVTWGVFP +EI+QPT+VDP SF +WKDEAF W + W+ LY
Sbjct: 485 VNNHDTVDITNCDSQTPVAVTWGVFPGREIVQPTVVDPISFKIWKDEAFSLWEQQWSRLY 544
Query: 20 PEADPS 3
E S
Sbjct: 545 TEDSKS 550
[30][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 139 bits (351), Expect = 8e-32
Identities = 65/126 (51%), Positives = 84/126 (66%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++NA+ S P VGWG GYV+QKAYLEFF S+E ++A+++ K + Y
Sbjct: 479 LTINSQPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYH 538
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
V+ + ++N + NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY
Sbjct: 539 IVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLY 598
Query: 20 PEADPS 3
E PS
Sbjct: 599 EEESPS 604
[31][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 139 bits (349), Expect = 1e-31
Identities = 65/126 (51%), Positives = 82/126 (65%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++N + S P VGWG GYV+QKAYLEFF S+E +A+++ K + Y
Sbjct: 503 LTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYH 562
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
VN + ++N + NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY
Sbjct: 563 LVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLY 622
Query: 20 PEADPS 3
E PS
Sbjct: 623 EEESPS 628
[32][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 139 bits (349), Expect = 1e-31
Identities = 65/126 (51%), Positives = 82/126 (65%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++N + S P VGWG GYV+QKAYLEFF S+E +A+++ K + Y
Sbjct: 521 LTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYH 580
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
VN + ++N + NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY
Sbjct: 581 LVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLY 640
Query: 20 PEADPS 3
E PS
Sbjct: 641 EEESPS 646
[33][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 139 bits (349), Expect = 1e-31
Identities = 65/126 (51%), Positives = 82/126 (65%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++N + S P VGWG GYV+QKAYLEFF S+E +A+++ K + Y
Sbjct: 480 LTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYH 539
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
VN + ++N + NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY
Sbjct: 540 LVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLY 599
Query: 20 PEADPS 3
E PS
Sbjct: 600 EEESPS 605
[34][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 138 bits (348), Expect = 2e-31
Identities = 65/126 (51%), Positives = 82/126 (65%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++N + S P VGWG GYV+QKAYLEFF S E ++A+++ K + Y
Sbjct: 474 LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSETVEALLQVLKKYELRVNYH 533
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
VN + ++N + NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY
Sbjct: 534 IVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLY 593
Query: 20 PEADPS 3
E PS
Sbjct: 594 EEESPS 599
[35][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 138 bits (348), Expect = 2e-31
Identities = 65/126 (51%), Positives = 82/126 (65%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++N + S P VGWG GYV+QKAYLEFF S+E +A+++ K + Y
Sbjct: 503 LTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYH 562
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
VN + ++N + NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY
Sbjct: 563 LVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLY 622
Query: 20 PEADPS 3
E PS
Sbjct: 623 EEESPS 628
[36][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 138 bits (348), Expect = 2e-31
Identities = 65/126 (51%), Positives = 82/126 (65%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++N + S P VGWG GYV+QKAYLEFF S+E +A+++ K + Y
Sbjct: 521 LTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYH 580
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
VN + ++N + NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY
Sbjct: 581 LVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLY 640
Query: 20 PEADPS 3
E PS
Sbjct: 641 EEESPS 646
[37][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 138 bits (348), Expect = 2e-31
Identities = 65/126 (51%), Positives = 82/126 (65%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++N + S P VGWG GYV+QKAYLEFF S+E +A+++ K + Y
Sbjct: 480 LTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYH 539
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
VN + ++N + NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY
Sbjct: 540 LVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLY 599
Query: 20 PEADPS 3
E PS
Sbjct: 600 EEESPS 605
[38][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 138 bits (348), Expect = 2e-31
Identities = 72/125 (57%), Positives = 83/125 (66%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+V+ RSD GWG GYVYQKAYLEFF S E LDA++ + +A P ITY A
Sbjct: 444 LTINSQPAVDGARSDDKVHGWGPKNGYVYQKAYLEFFVSPEDLDALIARIEADPQITYHA 503
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VN +NT NAVTWGVFP EIIQPTIV+ SF WKDEA+E R+WA +Y
Sbjct: 504 VNSQGDMRTNTNSEAPNAVTWGVFPHCEIIQPTIVESISFLAWKDEAYEI-GRNWAKVYE 562
Query: 17 EADPS 3
PS
Sbjct: 563 PTSPS 567
[39][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 138 bits (347), Expect = 2e-31
Identities = 65/126 (51%), Positives = 81/126 (64%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKAL-PSITYM 201
LTINSQP++N + S VGWG GYV+QKAYLEFF S E + A+++ K P + Y
Sbjct: 480 LTINSQPNINGKASSDAIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYQ 539
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
VN + ++N NAVTWG+FP +EIIQPT+VDP SF WKDEAF W WA LY
Sbjct: 540 IVNVQGRNITNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLY 599
Query: 20 PEADPS 3
+ PS
Sbjct: 600 EDESPS 605
[40][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 137 bits (346), Expect = 3e-31
Identities = 64/126 (50%), Positives = 83/126 (65%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++N + S P VGWG GYV+QKAYLEFF S+E ++A+++ K + Y
Sbjct: 479 LTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYH 538
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
V+ + ++N + NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY
Sbjct: 539 IVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLY 598
Query: 20 PEADPS 3
E PS
Sbjct: 599 EEESPS 604
[41][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 137 bits (346), Expect = 3e-31
Identities = 63/126 (50%), Positives = 83/126 (65%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++N + S P VGWG GYV+QKAYLEFF S+E ++A+++ K + Y
Sbjct: 485 LTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYH 544
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
V+ + ++N + NAVTWG+FP +EI+QPT+VDP SF WKDEAF W W LY
Sbjct: 545 IVDVKGENITNAPELQPNAVTWGIFPGREIVQPTVVDPISFMFWKDEAFALWIEQWGKLY 604
Query: 20 PEADPS 3
E PS
Sbjct: 605 EEESPS 610
[42][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 137 bits (346), Expect = 3e-31
Identities = 63/126 (50%), Positives = 83/126 (65%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++N + S P VGWG GYV+QKAYLEFF S+E ++A+++ K + Y
Sbjct: 520 LTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYH 579
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
V+ + ++N + NAVTWG+FP +EI+QPT+VDP SF WKDEAF W W LY
Sbjct: 580 IVDVKGENITNAPELQPNAVTWGIFPGREIVQPTVVDPISFMFWKDEAFALWIEQWGKLY 639
Query: 20 PEADPS 3
E PS
Sbjct: 640 EEESPS 645
[43][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 137 bits (346), Expect = 3e-31
Identities = 64/126 (50%), Positives = 83/126 (65%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++N + S P VGWG GYV+QKAYLEFF S+E ++A+++ K + Y
Sbjct: 479 LTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYH 538
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
V+ + ++N + NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY
Sbjct: 539 IVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLY 598
Query: 20 PEADPS 3
E PS
Sbjct: 599 EEESPS 604
[44][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 137 bits (346), Expect = 3e-31
Identities = 64/126 (50%), Positives = 83/126 (65%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++N + S P VGWG GYV+QKAYLEFF S+E ++A+++ K + Y
Sbjct: 479 LTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYH 538
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
V+ + ++N + NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY
Sbjct: 539 IVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLY 598
Query: 20 PEADPS 3
E PS
Sbjct: 599 EEESPS 604
[45][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 137 bits (345), Expect = 4e-31
Identities = 67/126 (53%), Positives = 81/126 (64%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++N + S P VGWG GYV+QKAYLEFF S E + A+++ K + Y
Sbjct: 482 LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYH 541
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
VN Q ++N NAVTWG+FP +EIIQPT+VDP SF WKDEAF W WA LY
Sbjct: 542 IVNVQGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY 601
Query: 20 PEADPS 3
E PS
Sbjct: 602 EEESPS 607
[46][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Canis lupus familiaris RepID=UPI00005A03BF
Length = 780
Score = 136 bits (343), Expect = 6e-31
Identities = 64/126 (50%), Positives = 82/126 (65%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++N + S P VGWG GYV+QKAYLEFF S+E + A+++ K + Y
Sbjct: 605 LTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYH 664
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
V+ + ++N + NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY
Sbjct: 665 IVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLY 724
Query: 20 PEADPS 3
E PS
Sbjct: 725 EEESPS 730
[47][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 136 bits (343), Expect = 6e-31
Identities = 65/126 (51%), Positives = 81/126 (64%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKAL-PSITYM 201
LTINSQP++N + S P VGWG GYVYQKAYLEFF S E + A+++ K P + Y
Sbjct: 484 LTINSQPNINGKPSTDPIVGWGPAGGYVYQKAYLEFFTSSENVTALLKVLKKYEPRVNYH 543
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
VN + ++N NAVTWG+F +EI+QPT+VDP SF WKDEAF W WA LY
Sbjct: 544 IVNVHGRNLTNAPDMQPNAVTWGIFAGREIVQPTVVDPVSFMSWKDEAFALWIEQWAKLY 603
Query: 20 PEADPS 3
+ PS
Sbjct: 604 EDESPS 609
[48][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 136 bits (343), Expect = 6e-31
Identities = 64/126 (50%), Positives = 82/126 (65%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++N + S P VGWG GYV+QKAYLEFF S+E + A+++ K + Y
Sbjct: 521 LTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYH 580
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
V+ + ++N + NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY
Sbjct: 581 IVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLY 640
Query: 20 PEADPS 3
E PS
Sbjct: 641 EEESPS 646
[49][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 136 bits (343), Expect = 6e-31
Identities = 65/126 (51%), Positives = 81/126 (64%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKAL-PSITYM 201
LTINSQP++N + S P VGWG GYVYQKAYLEFF S E + A+++ K P + Y
Sbjct: 484 LTINSQPNINGKPSTDPIVGWGPAGGYVYQKAYLEFFTSSENVTALLKVLKKYEPRVNYH 543
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
VN + ++N NAVTWG+F +EI+QPT+VDP SF WKDEAF W WA LY
Sbjct: 544 IVNVHGRNLTNAPDMQPNAVTWGIFAGREIVQPTVVDPVSFMSWKDEAFALWIEQWAKLY 603
Query: 20 PEADPS 3
+ PS
Sbjct: 604 EDESPS 609
[50][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 135 bits (340), Expect = 1e-30
Identities = 65/126 (51%), Positives = 80/126 (63%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++N + S P VGWG GYV+QKAYLEFF S E + A+++ K + Y
Sbjct: 477 LTINSQPNINGKPSADPVVGWGPSGGYVFQKAYLEFFTSSETVAALLKVLKKYELRVNYH 536
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
VN + ++N NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY
Sbjct: 537 IVNVKGENITNAPDMQPNAVTWGIFPGREIIQPTVVDPVSFMSWKDEAFALWIEQWGKLY 596
Query: 20 PEADPS 3
E PS
Sbjct: 597 EEESPS 602
[51][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
RepID=UPI0000E814FF
Length = 508
Score = 135 bits (340), Expect = 1e-30
Identities = 66/126 (52%), Positives = 80/126 (63%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++N + S P GWG GYV+QKAYLEFF S E + A+++ K + Y
Sbjct: 339 LTINSQPNINGKPSTDPIFGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYELRVNYH 398
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
VN Q ++N NAVTWG+FP +EIIQPT+VDP SF WKDEAF W WA LY
Sbjct: 399 IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY 458
Query: 20 PEADPS 3
E PS
Sbjct: 459 EEESPS 464
[52][TOP]
>UniRef100_UPI0000ECA34F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Gallus
gallus RepID=UPI0000ECA34F
Length = 640
Score = 135 bits (340), Expect = 1e-30
Identities = 66/126 (52%), Positives = 80/126 (63%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++N + S P GWG GYV+QKAYLEFF S E + A+++ K + Y
Sbjct: 471 LTINSQPNINGKPSTDPIFGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYELRVNYH 530
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
VN Q ++N NAVTWG+FP +EIIQPT+VDP SF WKDEAF W WA LY
Sbjct: 531 IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY 590
Query: 20 PEADPS 3
E PS
Sbjct: 591 EEESPS 596
[53][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 134 bits (337), Expect = 3e-30
Identities = 68/125 (54%), Positives = 81/125 (64%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN+ RSD P GWG GYVYQKAYLEFF + L+ ++ + +ITY
Sbjct: 428 LTINSQPAVNSARSDDPVFGWGPSNGYVYQKAYLEFFVNPTLLNLLLTHIERDSNITYYV 487
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
+NK +NT NAVTWGVFP KEI+QPTIV+ SF WKDEAFE + WA LY
Sbjct: 488 INKRGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFEL-GQQWAKLYE 546
Query: 17 EADPS 3
PS
Sbjct: 547 ANSPS 551
[54][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S5W8_NEMVE
Length = 619
Score = 133 bits (334), Expect = 7e-30
Identities = 66/126 (52%), Positives = 79/126 (62%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQPS+NA S+ P GWG P GYV+QKAYLEFF +E + + K I +
Sbjct: 454 LTINSQPSLNAVPSEDPNHGWGKPGGYVFQKAYLEFFAREEIALELYHQLKDGTRINFHL 513
Query: 197 VNK-GEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
VN GE +N NAVTWGVFP EI+QPT+VDP +F+ WKDEAF W + W LY
Sbjct: 514 VNSSGESDFTNANMYSPNAVTWGVFPGSEILQPTVVDPIAFHYWKDEAFGLWKQQWGRLY 573
Query: 20 PEADPS 3
PE S
Sbjct: 574 PEGSRS 579
[55][TOP]
>UniRef100_A8Q9P3 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8Q9P3_MALGO
Length = 515
Score = 130 bits (328), Expect = 4e-29
Identities = 67/124 (54%), Positives = 79/124 (63%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAV 195
TINSQP+V+ RSD P GWG GYVYQKAYLEFF S ++LD ++ + A P ITY AV
Sbjct: 354 TINSQPAVDGARSDDPVHGWGPKHGYVYQKAYLEFFVSPQQLDELIARFDAHPQITYHAV 413
Query: 194 NKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPE 15
N +NT NAVTWG FP EI+QPTIV+ SF WKDEA+E R WA Y
Sbjct: 414 NAQGDMRTNTTSDAPNAVTWGCFPHCEILQPTIVESMSFLAWKDEAYEI-GRRWAAFYEP 472
Query: 14 ADPS 3
P+
Sbjct: 473 ESPT 476
[56][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 129 bits (325), Expect = 8e-29
Identities = 70/127 (55%), Positives = 84/127 (66%), Gaps = 4/127 (3%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKA--LPSITY 204
LTINSQP VN S P VGWG G+VYQKAY+EFFC + +L+ ++ +A SI+Y
Sbjct: 411 LTINSQPRVNGALSTDPYVGWGPAGGFVYQKAYVEFFCPEGQLEQLIRGIEAEKYDSISY 470
Query: 203 MAVNK-GEQWVSNTA-QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWA 30
MAV G + SN Q VNAVTWGVFP EIIQPT+VD SF WKDEAF W+ W
Sbjct: 471 MAVTADGSKVRSNIPPQGQVNAVTWGVFPNSEIIQPTVVDVTSFMAWKDEAFALWN-EWM 529
Query: 29 NLYPEAD 9
++YPE D
Sbjct: 530 DVYPEDD 536
[57][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 129 bits (325), Expect = 8e-29
Identities = 70/127 (55%), Positives = 84/127 (66%), Gaps = 4/127 (3%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKA--LPSITY 204
LTINSQP VN S P VGWG G+VYQKAY+EFFC + +L+ ++ +A SI+Y
Sbjct: 390 LTINSQPRVNGALSTDPYVGWGPAGGFVYQKAYVEFFCPEGQLEQLIRGIEAEKYDSISY 449
Query: 203 MAVNK-GEQWVSNTA-QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWA 30
MAV G + SN Q VNAVTWGVFP EIIQPT+VD SF WKDEAF W+ W
Sbjct: 450 MAVTADGSKVRSNIPPQGQVNAVTWGVFPNSEIIQPTVVDVTSFMAWKDEAFALWN-EWM 508
Query: 29 NLYPEAD 9
++YPE D
Sbjct: 509 DVYPEDD 515
[58][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 129 bits (325), Expect = 8e-29
Identities = 67/125 (53%), Positives = 79/125 (63%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN RSD GWG GYVYQKAYLEFF L +++ + +ITY
Sbjct: 388 LTINSQPAVNGARSDDKIFGWGPSNGYVYQKAYLEFFVDPALLQLLLKHLERDTNITYHV 447
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
+NK +NT NAVTWGVFP KEIIQPTIV+ SF WKDEA+E ++ WA LY
Sbjct: 448 INKRGDLQTNTHSEGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAYELGAQ-WARLYE 506
Query: 17 EADPS 3
PS
Sbjct: 507 HDSPS 511
[59][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 129 bits (324), Expect = 1e-28
Identities = 67/126 (53%), Positives = 79/126 (62%), Gaps = 1/126 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP++N S GWGG G VY+KAY+EFF S E ++E K P ITY A
Sbjct: 445 LTINSQPAINGLPSTDKQHGWGGKNGIVYKKAYIEFFASPENTLKLIEYFKKCPMITYHA 504
Query: 197 VN-KGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
VN KG+ S T NAVTWG+FP KEIIQPT+VD SF VWKDEAF W W++ Y
Sbjct: 505 VNRKGD---SKTNTKGTNAVTWGIFPGKEIIQPTVVDHNSFMVWKDEAFALWETQWSSTY 561
Query: 20 PEADPS 3
+ S
Sbjct: 562 SPSSTS 567
[60][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 129 bits (323), Expect = 1e-28
Identities = 65/124 (52%), Positives = 79/124 (63%), Gaps = 2/124 (1%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LT NSQP+VNA S GWGG GY+YQKAYLEFF K+ +D ++E P + Y
Sbjct: 458 LTTNSQPAVNAALSTDERFGWGGAGGYIYQKAYLEFFMHKKNVDFLLEVLNDNPRVNYHI 517
Query: 197 VNK-GEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
++ G +N + AVTWGVFP KEIIQPT+VDP SFN WKDEAF W W +LY
Sbjct: 518 IDSHGCYDKTNADRYSPIAVTWGVFPGKEIIQPTVVDPISFNFWKDEAFSLWIEKWQSLY 577
Query: 20 -PEA 12
PE+
Sbjct: 578 EPES 581
[61][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 128 bits (322), Expect = 2e-28
Identities = 63/120 (52%), Positives = 75/120 (62%), Gaps = 1/120 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQPSVNA S + GWGGP GY+YQKAY E FCS E + +V K S+ A
Sbjct: 467 LTINSQPSVNAALSTHESFGWGGPGGYIYQKAYCECFCSPENMRCLVNMVKQNQSMNVYA 526
Query: 197 VNKGEQWV-SNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
VN + T V A+TWGVFP +EI+QPTI DP F VW +EAF W+ W+NLY
Sbjct: 527 VNNAGNCIQEGTELGGVTALTWGVFPNREILQPTIFDPRIFLVWAEEAFSLWTSMWSNLY 586
[62][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 128 bits (322), Expect = 2e-28
Identities = 65/125 (52%), Positives = 77/125 (61%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN +S PT GWG GYVYQKAYLE S E + ++ + + P TY A
Sbjct: 427 LTINSQPAVNGAKSSDPTFGWGPRNGYVYQKAYLEVLVSPEYIAEIITRIERDPEFTYYA 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK +N NAVTWGVFP KEI+QPTIV+ SF WKDE F + WAN +
Sbjct: 487 VNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDE-FYRLGQQWANCHG 545
Query: 17 EADPS 3
A PS
Sbjct: 546 GASPS 550
[63][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 128 bits (322), Expect = 2e-28
Identities = 64/125 (51%), Positives = 76/125 (60%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN +S P GWG GYVYQKAYLE F S E + ++ + + P TY A
Sbjct: 427 LTINSQPAVNGAKSSDPVFGWGPRNGYVYQKAYLEVFVSPEYISEIITRLERDPEFTYYA 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK +N NAVTWGVFP KEI+QPTIV+ SF WKDE F + WAN +
Sbjct: 487 VNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDE-FYRLGQQWANCHA 545
Query: 17 EADPS 3
PS
Sbjct: 546 GVSPS 550
[64][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 127 bits (319), Expect = 4e-28
Identities = 66/127 (51%), Positives = 81/127 (63%), Gaps = 2/127 (1%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKC-KALPSITYM 201
LTINSQP+VNA S P GWG GY+ QKAYLEFF +K +A+ K P + Y
Sbjct: 453 LTINSQPNVNAVPSTHPIYGWGDKGGYISQKAYLEFFINKHYAEALKTVLPKYHPRVNYH 512
Query: 200 AVNK-GEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANL 24
+NK G +N +++ NAVTWG+F KEIIQPT+VDP SF VWKDEAF W WA+L
Sbjct: 513 MINKCGTTDHTNADRSNPNAVTWGIFAGKEIIQPTVVDPVSFIVWKDEAFGLWHERWASL 572
Query: 23 YPEADPS 3
Y + S
Sbjct: 573 YEKGSKS 579
[65][TOP]
>UniRef100_Q8MQE7 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis elegans
RepID=Q8MQE7_CAEEL
Length = 642
Score = 124 bits (311), Expect = 3e-27
Identities = 61/128 (47%), Positives = 79/128 (61%), Gaps = 3/128 (2%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKC-KALP-SITY 204
LT+NSQPSVN S P VGWG P GY YQKAYLE F + E D +++ + P + Y
Sbjct: 475 LTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSDKLIQIIEREFPVRVNY 534
Query: 203 MAVNKGEQW-VSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWAN 27
A+NK + +N+ + AVTWGVFP EI QPT+VDP SF W+DEA++ W W +
Sbjct: 535 HAINKDSTFDKTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQWGD 594
Query: 26 LYPEADPS 3
YP+ S
Sbjct: 595 FYPKESKS 602
[66][TOP]
>UniRef100_Q17693 Probable methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis
elegans RepID=MTHR_CAEEL
Length = 663
Score = 124 bits (311), Expect = 3e-27
Identities = 61/128 (47%), Positives = 79/128 (61%), Gaps = 3/128 (2%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKC-KALP-SITY 204
LT+NSQPSVN S P VGWG P GY YQKAYLE F + E D +++ + P + Y
Sbjct: 496 LTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSDKLIQIIEREFPVRVNY 555
Query: 203 MAVNKGEQW-VSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWAN 27
A+NK + +N+ + AVTWGVFP EI QPT+VDP SF W+DEA++ W W +
Sbjct: 556 HAINKDSTFDKTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQWGD 615
Query: 26 LYPEADPS 3
YP+ S
Sbjct: 616 FYPKESKS 623
[67][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 124 bits (310), Expect = 4e-27
Identities = 61/119 (51%), Positives = 76/119 (63%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP++N E+S P GWG P GYV+QK Y+EFF L+ + E K L S++Y
Sbjct: 430 LTINSQPALNGEKSSHPVFGWGPPNGYVFQKPYVEFFVHPSLLNELKETVKKLNSVSYFV 489
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
NK +N+ NAVTWGVFP +EIIQPTIV+ SF WKDEA+ + WAN Y
Sbjct: 490 TNKNGDLDTNSQYEIPNAVTWGVFPNREIIQPTIVESTSFLAWKDEAY-SLGMEWANAY 547
[68][TOP]
>UniRef100_UPI0000123E6B Hypothetical protein CBG12960 n=1 Tax=Caenorhabditis briggsae AF16
RepID=UPI0000123E6B
Length = 662
Score = 122 bits (306), Expect = 1e-26
Identities = 61/129 (47%), Positives = 80/129 (62%), Gaps = 4/129 (3%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCS---KEKLDAVVEKCKALPSIT 207
LT+NSQPSVN S P VGWG P GY YQKAYLE F + EKL ++E+ + +
Sbjct: 497 LTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSEKLIDIIEREYPV-RVN 555
Query: 206 YMAVNKGEQW-VSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWA 30
Y A++K + +N+ + AVTWGVFP EI QPT+VDP SF W+DEA++ W W
Sbjct: 556 YHAIDKDSSFDKTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQWG 615
Query: 29 NLYPEADPS 3
+ YP+ S
Sbjct: 616 DFYPKESKS 624
[69][TOP]
>UniRef100_Q497H7 Mthfr protein (Fragment) n=2 Tax=Mus musculus RepID=Q497H7_MOUSE
Length = 166
Score = 122 bits (306), Expect = 1e-26
Identities = 57/116 (49%), Positives = 74/116 (63%), Gaps = 1/116 (0%)
Frame = -2
Query: 347 AERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVS 171
A+ S P VGWG GYV+QKAYLEFF S+E ++A+++ K + Y V+ + ++
Sbjct: 1 AKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENIT 60
Query: 170 NTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPS 3
N + NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY E PS
Sbjct: 61 NAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPS 116
[70][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 122 bits (305), Expect = 2e-26
Identities = 63/125 (50%), Positives = 73/125 (58%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
+TINSQP+VN +S P GWG GYVYQKAYLE S E + + + P ITY A
Sbjct: 427 ITINSQPAVNGVKSTHPVHGWGPANGYVYQKAYLELLVSPELFPEIKRRIEDHPDITYYA 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
V K +N NAVTWGVFP KEI+QPTIV+ SF WKDEAF+ WA Y
Sbjct: 487 VTKSGNLHTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQL-GLEWARCYD 545
Query: 17 EADPS 3
PS
Sbjct: 546 ADTPS 550
[71][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 121 bits (304), Expect = 2e-26
Identities = 62/125 (49%), Positives = 75/125 (60%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN +S P GWG GYVYQK+YLE D ++ + + P +TY A
Sbjct: 427 LTINSQPAVNGVKSSHPIHGWGPDNGYVYQKSYLELLVHPGVFDKMISRIENHPDLTYYA 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
V K + SN NAVTWGVFP KEI+QPTIV+ SF WKDEAF WA+ Y
Sbjct: 487 VTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRL-GVDWAHCYD 545
Query: 17 EADPS 3
+ PS
Sbjct: 546 ISSPS 550
[72][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 121 bits (304), Expect = 2e-26
Identities = 61/125 (48%), Positives = 77/125 (61%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN S P GWG GYVYQKAYLE E + V+ + + P +TY A
Sbjct: 427 LTINSQPAVNGMSSSHPVYGWGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNPDLTYYA 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
+NK + +NT+ + NAVTWG+F +KE+IQPTIV+ SF WKDEAF WA +
Sbjct: 487 INKNGELKTNTSDSP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAFRL-GDDWAKCHD 544
Query: 17 EADPS 3
PS
Sbjct: 545 ARSPS 549
[73][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 121 bits (304), Expect = 2e-26
Identities = 61/125 (48%), Positives = 77/125 (61%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN S P GWG GYVYQKAYLE E + V+ + + P +TY A
Sbjct: 427 LTINSQPAVNGMSSSHPVYGWGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNPDLTYYA 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
+NK + +NT+ + NAVTWG+F +KE+IQPTIV+ SF WKDEAF WA +
Sbjct: 487 INKNGELKTNTSDSP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAFRL-GDDWAKCHD 544
Query: 17 EADPS 3
PS
Sbjct: 545 ARSPS 549
[74][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 121 bits (304), Expect = 2e-26
Identities = 62/125 (49%), Positives = 75/125 (60%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
+T+NSQP+VN +S P GWG GYVYQKAYLE S E + ++ + P +TY A
Sbjct: 427 ITVNSQPAVNGVKSTHPVHGWGPSKGYVYQKAYLELLVSPEVYPEIKKRIENHPDLTYHA 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
V K +N NAVTWGVFP KEI+QPTIV+ SF WKDEAF+ S WA Y
Sbjct: 487 VTKSGMLETNAPSDAPNAVTWGVFPGKEIVQPTIVERISFLAWKDEAFQLGS-DWARCYE 545
Query: 17 EADPS 3
PS
Sbjct: 546 ADTPS 550
[75][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 120 bits (302), Expect = 4e-26
Identities = 61/125 (48%), Positives = 74/125 (59%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
+T+NSQP+VN +S P GWG GYVYQKAYLE S E + + ++ P +TY A
Sbjct: 427 ITVNSQPAVNGVKSTHPIHGWGPANGYVYQKAYLEMLISPELFPQIKSRIESHPDLTYHA 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
V K +N NAVTWGVFP KEI+QPTIV+ SF WKDEAF+ WA Y
Sbjct: 487 VTKSGNLHTNAQFEGPNAVTWGVFPGKEIVQPTIVERISFLAWKDEAFQL-GMEWARCYE 545
Query: 17 EADPS 3
PS
Sbjct: 546 TGTPS 550
[76][TOP]
>UniRef100_B6JY06 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6JY06_SCHJY
Length = 626
Score = 120 bits (302), Expect = 4e-26
Identities = 57/124 (45%), Positives = 76/124 (61%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAV 195
T+ SQP+VNA S GWG G+V+QKA++E F S +A+ ++ P ITY+A
Sbjct: 471 TVGSQPAVNAAPSSHAIFGWGPRGGWVFQKAFVEMFMSTMDFEALAQRLHDNPQITYLAG 530
Query: 194 NKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPE 15
N ++ +N + NAVTWGVFP +EIIQ TI+ P SF W+DEA+ W WA LYP
Sbjct: 531 NNKGEFKTNASLDSANAVTWGVFPGREIIQSTIIAPVSFQAWRDEAYSIWG-EWARLYPA 589
Query: 14 ADPS 3
PS
Sbjct: 590 GTPS 593
[77][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 120 bits (302), Expect = 4e-26
Identities = 61/125 (48%), Positives = 74/125 (59%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
+TINSQP+VN RS P GWG P GYVYQKAYLE + + E+ P +TY A
Sbjct: 422 ITINSQPAVNGVRSTHPIHGWGPPNGYVYQKAYLELLVHPAIFEQLKERIHDHPDLTYYA 481
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
V K +N NAVTWGVFP KEI+QPT+V+ SF WKDEAF+ WA +
Sbjct: 482 VTKSGNLHTNATYEGPNAVTWGVFPGKEIVQPTVVENISFLAWKDEAFQL-GMEWARCHD 540
Query: 17 EADPS 3
+ PS
Sbjct: 541 QNTPS 545
[78][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 120 bits (301), Expect = 5e-26
Identities = 58/125 (46%), Positives = 78/125 (62%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP++N +S P GWG GYVYQKAYLE S +D V+ + + P +TY
Sbjct: 427 LTINSQPAINGAKSSHPIYGWGPKNGYVYQKAYLELLISPTLIDEVIRRIETNPDLTYHC 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
+NK + +N++ NAVTWG+F +KE+IQPTIV+ SF WKDEA+ WA +
Sbjct: 487 INKNGELRTNSSDTP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRL-GDDWAKCHD 544
Query: 17 EADPS 3
+ PS
Sbjct: 545 ASSPS 549
[79][TOP]
>UniRef100_A8XGR9 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis briggsae
RepID=A8XGR9_CAEBR
Length = 724
Score = 120 bits (300), Expect = 6e-26
Identities = 61/139 (43%), Positives = 81/139 (58%), Gaps = 14/139 (10%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCS---KEKLDAVVEKCKALPSIT 207
LT+NSQPSVN S P VGWG P GY YQKAYLE F + EKL ++E+ + +
Sbjct: 547 LTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSEKLIDIIEREYPV-RVN 605
Query: 206 YMAVNKGEQWV-----------SNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDE 60
Y A++K ++ +N+ + AVTWGVFP EI QPT+VDP SF W+DE
Sbjct: 606 YHAIDKDVSYILNSHDSMQIFRTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDE 665
Query: 59 AFETWSRSWANLYPEADPS 3
A++ W W + YP+ S
Sbjct: 666 AYQMWMAQWGDFYPKESKS 684
[80][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
RepID=A8PV87_BRUMA
Length = 656
Score = 119 bits (299), Expect = 8e-26
Identities = 63/127 (49%), Positives = 75/127 (59%), Gaps = 2/127 (1%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQPS+N S P VGWG P GY YQKAYLEFF S+ + + + +
Sbjct: 495 LTINSQPSINGAPSTDPFVGWGKPGGYCYQKAYLEFFTSQANAEVLWSLLPSYSRLNCHI 554
Query: 197 VNKGE--QWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANL 24
VN W +NT AVTWGVFP EI QPT+VDP SF VWKDEAF W +W+++
Sbjct: 555 VNHDATIDW-TNTETTMPIAVTWGVFPGSEIAQPTVVDPLSFRVWKDEAFSAW-LNWSSI 612
Query: 23 YPEADPS 3
Y E S
Sbjct: 613 YAEGTSS 619
[81][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 119 bits (299), Expect = 8e-26
Identities = 60/125 (48%), Positives = 78/125 (62%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN +S P GWG GYVYQKAYLE E +D ++ + + P +TY
Sbjct: 428 LTINSQPAVNGVKSTDPVHGWGPRNGYVYQKAYLELLVPPEHVDELLRRIEKNPDLTYYC 487
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK + + + + NAVTWG+F +KEIIQPTIV+ SF WKDEA++ WA +P
Sbjct: 488 VNKTGELKARSDEGP-NAVTWGIFASKEIIQPTIVESVSFMAWKDEAYQL-GEDWAKCHP 545
Query: 17 EADPS 3
PS
Sbjct: 546 ADSPS 550
[82][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 119 bits (299), Expect = 8e-26
Identities = 60/125 (48%), Positives = 75/125 (60%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+V+ +S P GWG GYVYQKAYLE + + + +V + + P +TY A
Sbjct: 427 LTINSQPAVDGVKSSDPVYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQHDPDLTYYA 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
V K +N NAVTWGVFP KEI+QPTIV+ SF WKDEAF WA+ +
Sbjct: 487 VKKTGDLQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRL-GTDWAHCHS 545
Query: 17 EADPS 3
PS
Sbjct: 546 ALSPS 550
[83][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 119 bits (298), Expect = 1e-25
Identities = 63/125 (50%), Positives = 77/125 (61%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN +S P GWG GYVYQKAYLE + E + +V+K + IT+ A
Sbjct: 427 LTINSQPAVNGAKSTHPVHGWGPKNGYVYQKAYLELLVTPEVAEKLVKKLENQSEITFYA 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK +N A NAVTWG++P KE+IQPTIV+ SF WK+EAF S WA YP
Sbjct: 487 VNKTGNLQTN-APGGPNAVTWGIYPGKEVIQPTIVEKISFLAWKEEAFRLGS-EWAKCYP 544
Query: 17 EADPS 3
S
Sbjct: 545 AESES 549
[84][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 119 bits (297), Expect = 1e-25
Identities = 59/125 (47%), Positives = 77/125 (61%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LT+NSQP+VN RS P GWG G+VYQKAYLE F LD ++ + + P +TY A
Sbjct: 427 LTVNSQPAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLTYHA 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
V K + +NT + NA+TWG+F +EI+QPTIVD SF WKDEA+ WA +
Sbjct: 487 VAKNRELRTNTRDSP-NALTWGIFAGREIVQPTIVDTISFLAWKDEAYRL-GEDWAKCHD 544
Query: 17 EADPS 3
+ PS
Sbjct: 545 ASSPS 549
[85][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 119 bits (297), Expect = 1e-25
Identities = 59/125 (47%), Positives = 77/125 (61%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LT+NSQP+VN RS P GWG G+VYQKAYLE F LD ++ + + P +TY A
Sbjct: 427 LTVNSQPAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLTYHA 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
V K + +NT + NA+TWG+F +EI+QPTIVD SF WKDEA+ WA +
Sbjct: 487 VAKNRELRTNTRDSP-NALTWGIFAGREIVQPTIVDTISFLAWKDEAYRL-GEDWAKCHD 544
Query: 17 EADPS 3
+ PS
Sbjct: 545 ASSPS 549
[86][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 118 bits (295), Expect = 2e-25
Identities = 59/125 (47%), Positives = 76/125 (60%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP++N S P GWG GYVYQKAYLE E +D V+ + + +TY A
Sbjct: 427 LTINSQPAINGASSSHPVYGWGPKNGYVYQKAYLELLIPPEIIDEVITRIQKNADLTYYA 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
NK + +NT+ + NAVTWG+F +KE+IQPTIV+ SF WKDEA+ WA +
Sbjct: 487 TNKNGELKTNTSDSP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRL-GDDWAKCHD 544
Query: 17 EADPS 3
PS
Sbjct: 545 ARSPS 549
[87][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 117 bits (293), Expect = 4e-25
Identities = 60/125 (48%), Positives = 77/125 (61%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+++ S P GWG GYVYQKAYLE S +D V+ + + P +TY
Sbjct: 427 LTINSQPAIDGMPSSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYC 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK + +NT + NAVTWG+F +KEIIQPTIV+ SF WKDEA+ WA +
Sbjct: 487 VNKKGELRTNTTDSP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHV 544
Query: 17 EADPS 3
+ PS
Sbjct: 545 ASSPS 549
[88][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 117 bits (293), Expect = 4e-25
Identities = 58/125 (46%), Positives = 77/125 (61%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LT+NSQP+VN RS P GWG G+VYQKAYLE F LD ++ + + P +TY A
Sbjct: 427 LTVNSQPAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLTYHA 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
V K + +NT + NA+TWG+F +EI+QPTIV+ SF WKDEA+ WA +
Sbjct: 487 VAKNRELRTNTRDSP-NALTWGIFAGREIVQPTIVETISFLAWKDEAYRL-GEDWAKCHD 544
Query: 17 EADPS 3
+ PS
Sbjct: 545 ASSPS 549
[89][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 117 bits (292), Expect = 5e-25
Identities = 57/126 (45%), Positives = 84/126 (66%), Gaps = 2/126 (1%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS--ITYM 201
T+ SQP+V+A +S+ VGWG GYV+QKA++EFF ++++++ + EK + IT
Sbjct: 473 TVGSQPAVDAAKSEDEVVGWGPRGGYVFQKAFVEFFVTEDEVNRLKEKVEREGKGLITMY 532
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
A N+ + +NT + VNAVTWGVFP +EI Q TI++ SF WK+EAF+ W+ W+ LY
Sbjct: 533 AANRKGDFKTNTDKDSVNAVTWGVFPGQEIAQSTIIEETSFLAWKEEAFDIWA-EWSLLY 591
Query: 20 PEADPS 3
P PS
Sbjct: 592 PRNTPS 597
[90][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 117 bits (292), Expect = 5e-25
Identities = 59/125 (47%), Positives = 78/125 (62%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+++ S P GWG GYVYQKAYLE S ++ V+ + + +TY
Sbjct: 427 LTINSQPAIDGVHSSHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYC 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK + +NT+ + NAVTWG+F +KEIIQPTIV+ SF WKDEA+ WA +P
Sbjct: 487 VNKTGELRTNTSDSP-NAVTWGIFVSKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHP 544
Query: 17 EADPS 3
+ PS
Sbjct: 545 ASSPS 549
[91][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 117 bits (292), Expect = 5e-25
Identities = 59/125 (47%), Positives = 78/125 (62%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+++ S P GWG GYVYQKAYLE S ++ V+ + + +TY
Sbjct: 427 LTINSQPAIDGVHSSHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYC 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK + +NT+ + NAVTWG+F +KEIIQPTIV+ SF WKDEA+ WA +P
Sbjct: 487 VNKTGELRTNTSDSP-NAVTWGIFVSKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHP 544
Query: 17 EADPS 3
+ PS
Sbjct: 545 ASSPS 549
[92][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6H337_AJECH
Length = 524
Score = 116 bits (291), Expect = 7e-25
Identities = 60/125 (48%), Positives = 77/125 (61%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+++ S P GWG GYVYQKAYLE S +D V+ + + P +TY
Sbjct: 318 LTINSQPAIDGMPSSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYC 377
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK + +NT + NAVTWG+F +KEIIQPTIV+ SF WKDEA+ WA +
Sbjct: 378 VNKIGELRTNTTDSP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHV 435
Query: 17 EADPS 3
+ PS
Sbjct: 436 ASSPS 440
[93][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 116 bits (291), Expect = 7e-25
Identities = 59/125 (47%), Positives = 75/125 (60%), Gaps = 12/125 (9%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS----- 213
+T+NSQPS+N+ RS GWG GYVYQK YLEFFC K+ + +++
Sbjct: 432 ITLNSQPSLNSVRSSDKVFGWGPKNGYVYQKQYLEFFCHKDVVARLLDHIDQYNKNQGDS 491
Query: 212 ----ITYMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEA---F 54
I+Y AVNK +SN D+NAVTWGVFP +EI+QPTIV+ SF WKDE F
Sbjct: 492 TSAVISYYAVNKNGNLISNCQDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYTLF 551
Query: 53 ETWSR 39
WS+
Sbjct: 552 SEWSK 556
[94][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 116 bits (291), Expect = 7e-25
Identities = 59/125 (47%), Positives = 77/125 (61%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+++ S P GWG GYVYQKAYLE S ++ V+ + + +TY
Sbjct: 427 LTINSQPAIDGVHSSHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYC 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK + +NT + NAVTWG+F +KEIIQPTIV+ SF WKDEA+ WA +P
Sbjct: 487 VNKTGELRTNTTDSP-NAVTWGIFVSKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHP 544
Query: 17 EADPS 3
+ PS
Sbjct: 545 ASSPS 549
[95][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 116 bits (291), Expect = 7e-25
Identities = 60/125 (48%), Positives = 77/125 (61%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+++ S P GWG GYVYQKAYLE S +D V+ + + P +TY
Sbjct: 413 LTINSQPAIDGMPSSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYC 472
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
VNK + +NT + NAVTWG+F +KEIIQPTIV+ SF WKDEA+ WA +
Sbjct: 473 VNKIGELRTNTTDSP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHG 530
Query: 17 EADPS 3
+ PS
Sbjct: 531 ASSPS 535
[96][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 115 bits (288), Expect = 2e-24
Identities = 57/131 (43%), Positives = 83/131 (63%), Gaps = 8/131 (6%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP------ 216
LTINSQP VN S+ GWG G+VYQK YLEFF + L ++ + L
Sbjct: 425 LTINSQPCVNGLPSNHNVHGWGPSNGFVYQKQYLEFFIPAKFLTKLISNIEELNKSYSSN 484
Query: 215 --SITYMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWS 42
++T+ AVN + ++N+ + D+NAVTWG+FP KE++QPTIV+ SF WKDEAF +
Sbjct: 485 FNTLTFYAVNAQGELITNSKEDDINAVTWGIFPGKEVVQPTIVERCSFLAWKDEAFRVF- 543
Query: 41 RSWANLYPEAD 9
++W++L+ + D
Sbjct: 544 KAWSSLFKDQD 554
[97][TOP]
>UniRef100_C9S7I3 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S7I3_9PEZI
Length = 312
Score = 115 bits (287), Expect = 2e-24
Identities = 57/125 (45%), Positives = 73/125 (58%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
+TINSQP+VN +S GWG GYVYQK+YLE + ++ + + P +TY A
Sbjct: 135 ITINSQPAVNGVKSSHAVHGWGPKNGYVYQKSYLEMLVHPDLYPEIISRIEKHPDMTYYA 194
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
V K N NAVTWGVFP KEI+QPTIV+ SF WKDEAF WA+ +
Sbjct: 195 VTKSGNLKYNAPSDGPNAVTWGVFPGKEIVQPTIVEGISFVAWKDEAFRL-GLDWAHCFE 253
Query: 17 EADPS 3
++ PS
Sbjct: 254 QSSPS 258
[98][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 115 bits (287), Expect = 2e-24
Identities = 57/125 (45%), Positives = 78/125 (62%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN +S P GWG G+VYQKAYLE E ++ ++ + + P +TY
Sbjct: 428 LTINSQPAVNGVKSTDPVHGWGPRNGFVYQKAYLELLVPPEHVEELLRRIEKNPDLTYYC 487
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
+NK + + + + NAVTWG+F +KEIIQPTIV+ SF WKDEA++ WA +P
Sbjct: 488 INKTGELRARSDEGP-NAVTWGIFASKEIIQPTIVESVSFMAWKDEAYQL-GDDWAKCHP 545
Query: 17 EADPS 3
PS
Sbjct: 546 ADSPS 550
[99][TOP]
>UniRef100_UPI000151BABB hypothetical protein PGUG_04648 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151BABB
Length = 355
Score = 114 bits (285), Expect = 3e-24
Identities = 58/127 (45%), Positives = 81/127 (63%), Gaps = 8/127 (6%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKE---KLDAVVEKC-----KA 222
LT+NSQPS+N +S+ GWG GYV+QK YLEFFC ++ KL +EK ++
Sbjct: 172 LTMNSQPSLNCVKSNDKVYGWGPKNGYVFQKQYLEFFCHRDIFPKLLESIEKFNEKGGES 231
Query: 221 LPSITYMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWS 42
+TY A +K + +NT + D+NAVTWGVFP +EI+QPTIV+ SF WKDE + +
Sbjct: 232 CSFLTYYAADKNGELNTNTKEDDINAVTWGVFPGEEILQPTIVEKTSFFAWKDEVYRLLA 291
Query: 41 RSWANLY 21
W ++Y
Sbjct: 292 -EWGSVY 297
[100][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 114 bits (285), Expect = 3e-24
Identities = 54/105 (51%), Positives = 71/105 (67%), Gaps = 1/105 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYM 201
LTINSQP++N + S P VGWG GYV+QKAYLEFF S+E +A+++ K + Y
Sbjct: 510 LTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYH 569
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWK 66
VN + ++N + NAVTWG+FP +EIIQPT+VDP SF WK
Sbjct: 570 LVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWK 614
[101][TOP]
>UniRef100_A5DMZ7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DMZ7_PICGU
Length = 355
Score = 114 bits (285), Expect = 3e-24
Identities = 58/127 (45%), Positives = 81/127 (63%), Gaps = 8/127 (6%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKE---KLDAVVEKC-----KA 222
LT+NSQPS+N +S+ GWG GYV+QK YLEFFC ++ KL +EK ++
Sbjct: 172 LTMNSQPSLNCVKSNDKVYGWGPKNGYVFQKQYLEFFCHRDIFPKLLESIEKFNEKGGES 231
Query: 221 LPSITYMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWS 42
+TY A +K + +NT + D+NAVTWGVFP +EI+QPTIV+ SF WKDE + +
Sbjct: 232 CSFLTYYAADKNGELNTNTKEDDINAVTWGVFPGEEILQPTIVEKTSFFAWKDEVYRLLA 291
Query: 41 RSWANLY 21
W ++Y
Sbjct: 292 -EWGSVY 297
[102][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 114 bits (284), Expect = 4e-24
Identities = 58/125 (46%), Positives = 74/125 (59%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LT+NSQP+VN +S GWG GYVYQK+YLE + + ++ + + P +T+ A
Sbjct: 427 LTVNSQPAVNGVKSSHAVHGWGPSNGYVYQKSYLELLVHPDVFNDMIGRIENHPDLTFYA 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
V K + SN NAVTWGVFP KEI+QPTIV+ SF WKDEAF WA+ Y
Sbjct: 487 VTKDGELRSNAPSDCPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRL-GVDWAHCYD 545
Query: 17 EADPS 3
PS
Sbjct: 546 ANSPS 550
[103][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 114 bits (284), Expect = 4e-24
Identities = 58/125 (46%), Positives = 76/125 (60%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LT+NSQP+VN RS P GWG G+VYQKAYLE F LD ++ + + +TY A
Sbjct: 427 LTVNSQPAVNGVRSSHPVYGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNDDLTYHA 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
V K + +NT + NA+TWG+F +EI+QPTIV+ SF WKDEA+ WA +
Sbjct: 487 VAKEGELRTNTRDSP-NALTWGIFAGREIVQPTIVETISFLAWKDEAYRL-GEDWAKCHE 544
Query: 17 EADPS 3
A PS
Sbjct: 545 AASPS 549
[104][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 113 bits (283), Expect = 6e-24
Identities = 57/127 (44%), Positives = 76/127 (59%), Gaps = 9/127 (7%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS----- 213
LT+NSQP++NA +S GWG GYVYQK YLEFFC K+ L ++ +
Sbjct: 432 LTMNSQPALNAVKSSEKVYGWGPKNGYVYQKQYLEFFCPKDLLPKLLHTIDSYNKSEGDA 491
Query: 212 ----ITYMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETW 45
I+Y AV+K +N D+NAVTWGVFP +EI+QPTIV+ SF WKDE + +
Sbjct: 492 SSSIISYYAVDKNGNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLF 551
Query: 44 SRSWANL 24
+ W N+
Sbjct: 552 T-EWTNI 557
[105][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 112 bits (279), Expect = 2e-23
Identities = 58/134 (43%), Positives = 80/134 (59%), Gaps = 12/134 (8%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKAL-------- 219
T+NSQP++NA +S GWG GYVYQK YLEFFC K+ + ++++ +
Sbjct: 433 TMNSQPALNAVKSSEKVFGWGPKNGYVYQKQYLEFFCHKDVVSKLLDQVEEFNIKGAESS 492
Query: 218 -PSITYMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEA---FE 51
I+Y AV+K +N D+NAVTWGVFP +EI+QPTIV+ SF WKDE F
Sbjct: 493 SAFISYYAVDKDGNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFT 552
Query: 50 TWSRSWANLYPEAD 9
W++ ++ EAD
Sbjct: 553 EWAKIASSNLVEAD 566
[106][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 111 bits (278), Expect = 2e-23
Identities = 57/119 (47%), Positives = 75/119 (63%), Gaps = 3/119 (2%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+++ S P GWG GYVYQKAYLE S +D V+ + + +TY
Sbjct: 427 LTINSQPAIDGMPSSHPIYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNSDLTYYC 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAF---ETWSRSWA 30
VNK + +NT + NAVTWG+F +KEIIQPTIV+ SF WKDEA+ + W++ A
Sbjct: 487 VNKKGELKTNTTDSP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRLGDDWAKCHA 544
[107][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 111 bits (278), Expect = 2e-23
Identities = 57/119 (47%), Positives = 75/119 (63%), Gaps = 3/119 (2%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+++ S P GWG GYVYQKAYLE S +D V+ + + +TY
Sbjct: 427 LTINSQPAIDGMPSSHPIYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNSDLTYYC 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAF---ETWSRSWA 30
VNK + +NT + NAVTWG+F +KEIIQPTIV+ SF WKDEA+ + W++ A
Sbjct: 487 VNKKGELKTNTTDSP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRLGDDWAKCHA 544
[108][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 111 bits (278), Expect = 2e-23
Identities = 56/125 (44%), Positives = 75/125 (60%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN +S P GWG G+VYQKAYLE +D ++ + + +TY A
Sbjct: 427 LTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSNLIDELITRIEKNDDLTYHA 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
NK + +NT + NA+TWG+F +EIIQPTIV+ SF WKDEA+ W+ +
Sbjct: 487 TNKKGELKTNTRDSP-NALTWGIFAGREIIQPTIVETVSFLAWKDEAY-LLGEHWSKCHD 544
Query: 17 EADPS 3
A PS
Sbjct: 545 AASPS 549
[109][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 111 bits (277), Expect = 3e-23
Identities = 55/120 (45%), Positives = 70/120 (58%), Gaps = 1/120 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LT+NSQP V+ S GWGG G VYQKAY E F S K + + + PS+ A
Sbjct: 428 LTVNSQPPVDGLPSCHKVFGWGGKGGRVYQKAYFECFVSPSKANRLTQMVTDHPSLNMYA 487
Query: 197 VNK-GEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
VN G++ + V A+TWGVFP +EI+QPTI DP +F +W +EAF W W NLY
Sbjct: 488 VNNAGQELRVGVEEGGVTALTWGVFPNREILQPTIFDPDTFLIWAEEAFSLWGSMWLNLY 547
[110][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 111 bits (277), Expect = 3e-23
Identities = 55/125 (44%), Positives = 75/125 (60%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP+VN +S P GWG G+VYQKAYLE LD ++ + + +TY A
Sbjct: 427 LTINSQPAVNGAKSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIEGNEDLTYHA 486
Query: 197 VNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
V+K + +NT + NA+TWG+F +E++QPTIV+ SF WKDEA+ WA +
Sbjct: 487 VSKNGELRTNTHDSP-NALTWGIFAGREVVQPTIVETISFLAWKDEAYRL-GEDWAKCHA 544
Query: 17 EADPS 3
PS
Sbjct: 545 ATSPS 549
[111][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 110 bits (276), Expect = 4e-23
Identities = 55/126 (43%), Positives = 76/126 (60%), Gaps = 9/126 (7%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKAL-------- 219
T+NSQP++NA +S GWG GYVYQK YLEFFC K+ + +++ +
Sbjct: 433 TMNSQPALNAVKSSEKVFGWGPKNGYVYQKQYLEFFCHKDVVSKLLDHVEEFNVKGAESS 492
Query: 218 -PSITYMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWS 42
I+Y AV+K +N D+NAVTWGVFP +EI+QPTIV+ SF WKDE + ++
Sbjct: 493 SAFISYYAVDKDGNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFT 552
Query: 41 RSWANL 24
WA +
Sbjct: 553 -EWAKI 557
[112][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 110 bits (275), Expect = 5e-23
Identities = 56/117 (47%), Positives = 71/117 (60%), Gaps = 4/117 (3%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LT+NSQP VN S VGWG GYVYQK YLEF K KL + + +PS+TY A
Sbjct: 437 LTLNSQPRVNGASSADKIVGWGPNNGYVYQKQYLEFLLPKSKLSQLRDFVNDMPSLTYFA 496
Query: 197 VNKGEQWVSN-TAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAF---ETWSR 39
V+ ++ SN NAVTWG+FP +E++QPTIV+ SF WK+E F + W R
Sbjct: 497 VDSADELHSNHPDDTAANAVTWGIFPGREVLQPTIVEKVSFLAWKEEFFDILDEWKR 553
[113][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 110 bits (274), Expect = 6e-23
Identities = 59/122 (48%), Positives = 74/122 (60%), Gaps = 2/122 (1%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKA-LPSITYMA 198
TINSQP VN + S P VGWG GYVYQK YLEF +EKL E C+ +TY A
Sbjct: 442 TINSQPKVNGKPSTDPVVGWGPTKGYVYQKEYLEFLLPREKLPLFQEICQEHSDHLTYFA 501
Query: 197 VNKGEQWVSNTAQ-ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
++ + +N + + NAVTWGVFP EI+QPTIV+ ASF WK+E F T + W +
Sbjct: 502 IDSQDNLATNHPEDSRANAVTWGVFPGSEILQPTIVEKASFLAWKEEFF-TILKEWKLTF 560
Query: 20 PE 15
E
Sbjct: 561 VE 562
[114][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 110 bits (274), Expect = 6e-23
Identities = 55/124 (44%), Positives = 74/124 (59%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAV 195
TINSQP+VN RS P GWG G+VYQKAYLE LD ++ + + +TY AV
Sbjct: 428 TINSQPAVNGARSSHPVYGWGPKNGFVYQKAYLELLVPPYLLDELIARIEKNEDLTYHAV 487
Query: 194 NKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPE 15
+K + +NT + NA+TWG+F +E++QPTIV+ SF WKDEA+ WA +
Sbjct: 488 SKTGELRTNTRDSP-NALTWGIFAGREVVQPTIVETISFLAWKDEAYRL-GEDWAKCHEA 545
Query: 14 ADPS 3
PS
Sbjct: 546 GSPS 549
[115][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 109 bits (273), Expect = 8e-23
Identities = 53/124 (42%), Positives = 76/124 (61%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAV 195
TINSQP+VN +S P GWG G+VYQKAYLE +D ++ + +A +TY AV
Sbjct: 428 TINSQPAVNGVKSSHPVFGWGPKNGFVYQKAYLELLVPPYVIDELIARIEANEDLTYHAV 487
Query: 194 NKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPE 15
K + +NT + NA+TWG+F +E++QPTIV+ SF WKDEA++ WA +
Sbjct: 488 TKKGELRTNTRDSP-NALTWGIFAGREVVQPTIVETVSFLAWKDEAYQL-GEDWAKCHEA 545
Query: 14 ADPS 3
+ P+
Sbjct: 546 SSPT 549
[116][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 109 bits (273), Expect = 8e-23
Identities = 57/113 (50%), Positives = 74/113 (65%), Gaps = 6/113 (5%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDA---VVEKCKALPS--- 213
T+NSQP+++A RS+ GWG G+VYQK YLEF K+KL +VEK A +
Sbjct: 435 TLNSQPALSAVRSNDKLYGWGPKNGFVYQKQYLEFLVRKDKLKELLDIVEKHNAKDTYGL 494
Query: 212 ITYMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAF 54
ITY AV+K +N+ D+NAVTWGVFP +EI+QPTIV+ SF WKDE +
Sbjct: 495 ITYYAVDKSGNLHTNSKNDDINAVTWGVFPGEEILQPTIVEKVSFLAWKDEVY 547
[117][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 109 bits (272), Expect = 1e-22
Identities = 55/116 (47%), Positives = 73/116 (62%), Gaps = 9/116 (7%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS------ 213
T+NSQPS+NA +S+ GWG GYVYQK YLEFF K+ + A++ +
Sbjct: 433 TLNSQPSLNAIKSNDKVYGWGPKNGYVYQKQYLEFFVHKDIIPALLHQIDNYNRGQGDSN 492
Query: 212 ---ITYMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAF 54
+TY AV++ + SNT D+NAVTWGVFP +EI+QPTIV+ SF WKDE +
Sbjct: 493 SSVLTYYAVDQKGKLFSNTKDDDINAVTWGVFPGEEILQPTIVEKVSFLAWKDEVY 548
[118][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 109 bits (272), Expect = 1e-22
Identities = 57/110 (51%), Positives = 67/110 (60%), Gaps = 2/110 (1%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKA-LPSITYM 201
LTINSQP VN S P VGWG GYVYQK YLEF K L A A P++TY
Sbjct: 440 LTINSQPKVNGAPSADPIVGWGPANGYVYQKQYLEFLLPKHHLPAFHAALTADFPTLTYF 499
Query: 200 AVNKGEQWVSN-TAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAF 54
AV+ + SN NAVTWG+FP +E++QPTIV+ ASF WKDE +
Sbjct: 500 AVDADDNLASNHPDDTQANAVTWGIFPGREVLQPTIVEKASFLAWKDEFY 549
[119][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 109 bits (272), Expect = 1e-22
Identities = 55/116 (47%), Positives = 73/116 (62%), Gaps = 9/116 (7%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS------ 213
T+NSQPS+NA +S+ GWG GYVYQK YLEFF K+ + A++ +
Sbjct: 433 TLNSQPSLNAIKSNDKVYGWGPKNGYVYQKQYLEFFVHKDIIPALLHQIDNYNRGQGDSN 492
Query: 212 ---ITYMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAF 54
+TY AV++ + SNT D+NAVTWGVFP +EI+QPTIV+ SF WKDE +
Sbjct: 493 SSVLTYYAVDQKGKLFSNTKDDDINAVTWGVFPGEEILQPTIVEKVSFLAWKDEVY 548
[120][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 109 bits (272), Expect = 1e-22
Identities = 55/124 (44%), Positives = 75/124 (60%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAV 195
TINSQP+VN +S P GWG GYVYQKAYLE +D ++ + + +TY AV
Sbjct: 428 TINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNGDLTYHAV 487
Query: 194 NKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPE 15
+K + +NT + NA+TWG+F +EI+QPTIV+ SF WKDEA+ WA +
Sbjct: 488 SKTGELRTNTRDSP-NALTWGIFAGREIVQPTIVETVSFLAWKDEAYRL-GDDWAKCHDT 545
Query: 14 ADPS 3
+ PS
Sbjct: 546 SSPS 549
[121][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR2_SCHPO
Length = 641
Score = 108 bits (271), Expect = 1e-22
Identities = 52/124 (41%), Positives = 73/124 (58%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAV 195
T+ SQP+VN S P GWG G V+QKA++E F + + L + K P +TY A
Sbjct: 484 TVGSQPAVNGAPSADPVFGWGPKGGRVFQKAFVECFVNGKDLKDFITKWHDNPQVTYYAG 543
Query: 194 NKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPE 15
N ++++N + +AVTWGV+P +EIIQ TI+ SF W E+F+ W WANLY +
Sbjct: 544 NNKSEFLTNAPKDGASAVTWGVYPGREIIQSTIIAEVSFKAWLSESFQVWG-EWANLYSK 602
Query: 14 ADPS 3
PS
Sbjct: 603 NTPS 606
[122][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NEV2_COPC7
Length = 617
Score = 108 bits (269), Expect = 2e-22
Identities = 52/120 (43%), Positives = 74/120 (61%), Gaps = 2/120 (1%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS--ITYM 201
T+ SQP+V+ S T GWG GYV+QK ++EFFC ++A+ ++ K + + Y
Sbjct: 454 TVGSQPAVDGISSSDETFGWGPRAGYVFQKGFVEFFCDFHDVEAIEQRIKQRGAGWVHYF 513
Query: 200 AVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
N + SN + NAVTWGVFP +EI Q TI++ SF WKDEA++ W+ SWA+LY
Sbjct: 514 MANNNGECRSNVPEDGRNAVTWGVFPGQEIQQTTIIEKESFLTWKDEAYDIWN-SWASLY 572
[123][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 107 bits (267), Expect = 4e-22
Identities = 53/127 (41%), Positives = 77/127 (60%), Gaps = 3/127 (2%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS---ITY 204
++ SQP+V+ S P VG+G P G+V+QK+++E F S D +V + AL + ITY
Sbjct: 526 SVGSQPAVDGAPSTDPIVGFGPPGGFVFQKSFVELFVSSSDKDRLVARIDALGASAPITY 585
Query: 203 MAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANL 24
A N + SN + N VTW VFP KEI+Q TI++ SF W++EAFE W+ W+ L
Sbjct: 586 FAGNAKGDFQSNLGDEEANTVTWAVFPGKEIVQSTIIERQSFEAWREEAFEIWA-EWSLL 644
Query: 23 YPEADPS 3
+P+ S
Sbjct: 645 FPKKSAS 651
[124][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 105 bits (262), Expect = 2e-21
Identities = 55/124 (44%), Positives = 73/124 (58%), Gaps = 12/124 (9%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS----- 213
LT+NSQP++N+ +S GWG GYVYQK YLEFFC K D +V+ + +
Sbjct: 433 LTMNSQPALNSIKSSEKIFGWGPKNGYVYQKQYLEFFCHK---DIIVKLLQTIDDYNNNQ 489
Query: 212 -------ITYMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAF 54
I+Y AV+ +N D+NAVTWGVFP +EI+QPTIV+ SF WKDE +
Sbjct: 490 GDASSAIISYYAVDLKGNLTTNCNDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVY 549
Query: 53 ETWS 42
+S
Sbjct: 550 RLFS 553
[125][TOP]
>UniRef100_Q0UB79 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UB79_PHANO
Length = 543
Score = 104 bits (260), Expect = 3e-21
Identities = 51/124 (41%), Positives = 71/124 (57%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAV 195
T+ SQP+VN RS P GWG GYV+QK ++EFF + A+ + A +TY A
Sbjct: 389 TVASQPAVNGVRSTDPVFGWGPKNGYVFQKPFVEFFLPAAEFHALRTRLDAHDQVTYFAG 448
Query: 194 NKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPE 15
N + +++ ++ VN VTWG F KEI+ PTI++ SF W +EAF W R W +YP
Sbjct: 449 NANGDFEASSEES-VNPVTWGTFAGKEIVTPTIIEAVSFRSWLEEAFSIW-REWQRIYPT 506
Query: 14 ADPS 3
S
Sbjct: 507 KSAS 510
[126][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 103 bits (258), Expect = 5e-21
Identities = 51/109 (46%), Positives = 70/109 (64%), Gaps = 1/109 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
+TINSQP VN RS+ GWG GYVYQK YLEF K KL +++ K +TY A
Sbjct: 439 ITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFA 498
Query: 197 V-NKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAF 54
+ ++G+ ++ + NAVTWG+FP +EI+QPTIV+ SF WK+E +
Sbjct: 499 IDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFY 547
[127][TOP]
>UniRef100_B5VIK4 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VIK4_YEAS6
Length = 411
Score = 103 bits (258), Expect = 5e-21
Identities = 51/109 (46%), Positives = 70/109 (64%), Gaps = 1/109 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
+TINSQP VN RS+ GWG GYVYQK YLEF K KL +++ K +TY A
Sbjct: 250 ITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFA 309
Query: 197 V-NKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAF 54
+ ++G+ ++ + NAVTWG+FP +EI+QPTIV+ SF WK+E +
Sbjct: 310 IDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFY 358
[128][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 103 bits (258), Expect = 5e-21
Identities = 51/109 (46%), Positives = 70/109 (64%), Gaps = 1/109 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
+TINSQP VN RS+ GWG GYVYQK YLEF K KL +++ K +TY A
Sbjct: 439 ITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFA 498
Query: 197 V-NKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAF 54
+ ++G+ ++ + NAVTWG+FP +EI+QPTIV+ SF WK+E +
Sbjct: 499 IDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFY 547
[129][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1CZX0_NEOFI
Length = 716
Score = 103 bits (258), Expect = 5e-21
Identities = 59/140 (42%), Positives = 78/140 (55%), Gaps = 16/140 (11%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKCKAL---PSIT 207
T+ SQP+VN RSD PT GWG P G+V+QK ++EFFC + V++ A +
Sbjct: 531 TLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEFFCPSKDFQTVLKPLFAKHGHEKLA 590
Query: 206 YMAVN-KGE---QWVSNTAQAD--------VNAVTWGVFPAKEIIQPTIVDPASFNVWKD 63
+ A N KGE ++ A AD VNAVTWGVF KEI+ PTI++ SF W +
Sbjct: 591 WFATNVKGEFESSLPADPAHADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGE 650
Query: 62 EAFETWSRSWANLYPEADPS 3
EAF W W +YP P+
Sbjct: 651 EAFRIWD-EWRRVYPRGTPT 669
[130][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 103 bits (258), Expect = 5e-21
Identities = 51/109 (46%), Positives = 70/109 (64%), Gaps = 1/109 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
+TINSQP VN RS+ GWG GYVYQK YLEF K KL +++ K +TY A
Sbjct: 439 ITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFA 498
Query: 197 V-NKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAF 54
+ ++G+ ++ + NAVTWG+FP +EI+QPTIV+ SF WK+E +
Sbjct: 499 IDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFY 547
[131][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 103 bits (256), Expect = 8e-21
Identities = 51/115 (44%), Positives = 70/115 (60%), Gaps = 4/115 (3%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
+TINSQP +N RS+ GWG GYVYQK YLEF EK++ + ++ +TY A
Sbjct: 439 ITINSQPQINGIRSNHKVHGWGPKDGYVYQKQYLEFLLPNEKVEKLEKQLAGNEMLTYFA 498
Query: 197 VNKGEQWVSNTAQ-ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAF---ETW 45
V+ + SN + NAVTWG+FP +E++QPTIV+ SF WK+E + E W
Sbjct: 499 VDNKDNLKSNHPDGSKANAVTWGIFPGREVLQPTIVEKVSFLAWKEEFYRILEEW 553
[132][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 103 bits (256), Expect = 8e-21
Identities = 59/140 (42%), Positives = 78/140 (55%), Gaps = 16/140 (11%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKCKAL---PSIT 207
T+ SQP+VN RSD PT GWG P G+V+QK ++EFFC + V++ A +
Sbjct: 504 TLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEFFCPSKDFRTVLKPLFAKHGHEKLA 563
Query: 206 YMAVN-KGE---QWVSNTAQAD--------VNAVTWGVFPAKEIIQPTIVDPASFNVWKD 63
+ A N KGE ++ A AD VNAVTWGVF KEI+ PTI++ SF W +
Sbjct: 564 WFATNVKGEFESSLPADPAHADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGE 623
Query: 62 EAFETWSRSWANLYPEADPS 3
EAF W W +YP P+
Sbjct: 624 EAFRIWD-EWRRVYPRGTPT 642
[133][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 103 bits (256), Expect = 8e-21
Identities = 55/120 (45%), Positives = 75/120 (62%), Gaps = 1/120 (0%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
LTINSQP V A S P GWG GYV+QKAYLEFF +++ +++E + ++ Y
Sbjct: 435 LTINSQPPVCAAPSTDPLFGWGPAHGYVFQKAYLEFFMHPDQVKSLLEVIPSFKTVQYY- 493
Query: 197 VNKGEQWVSNTAQADV-NAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
+ E + + DV +AVTWGVFP E+IQPT+V+ ASF WKDEA+ + SWA +
Sbjct: 494 ITDYEGSLETNGELDVPSAVTWGVFPNSEVIQPTVVESASFLAWKDEAY-SLGLSWAKAH 552
[134][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 103 bits (256), Expect = 8e-21
Identities = 59/140 (42%), Positives = 78/140 (55%), Gaps = 16/140 (11%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKCKAL---PSIT 207
T+ SQP+VN RSD PT GWG P G+V+QK ++EFFC + V++ A +
Sbjct: 504 TLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEFFCPSKDFRTVLKPLFAKHGHEKLA 563
Query: 206 YMAVN-KGE---QWVSNTAQAD--------VNAVTWGVFPAKEIIQPTIVDPASFNVWKD 63
+ A N KGE ++ A AD VNAVTWGVF KEI+ PTI++ SF W +
Sbjct: 564 WFATNVKGEFESSLPADPAHADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGE 623
Query: 62 EAFETWSRSWANLYPEADPS 3
EAF W W +YP P+
Sbjct: 624 EAFRIWD-EWRRVYPRGTPT 642
[135][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TTE9_VANPO
Length = 612
Score = 102 bits (255), Expect = 1e-20
Identities = 54/129 (41%), Positives = 75/129 (58%), Gaps = 5/129 (3%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKC----KALPSI 210
+TINSQP VN RS+ GWG GYVYQK YLEF + + + + ++ + S+
Sbjct: 434 VTINSQPQVNGLRSNVKGFGWGPSDGYVYQKQYLEFLLPRARFERLQQELSKTNETTSSL 493
Query: 209 TYMAVNKGEQWVSNTAQ-ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSW 33
TY+A + W SN A AVTWGVFP +E++QPTIV+ SF W+DE F + W
Sbjct: 494 TYLAADSHGGWWSNQPDGAKATAVTWGVFPGREVLQPTIVEKISFLAWRDE-FYRILQDW 552
Query: 32 ANLYPEADP 6
+++ A P
Sbjct: 553 RDIFVHASP 561
[136][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 102 bits (253), Expect = 2e-20
Identities = 53/121 (43%), Positives = 69/121 (57%), Gaps = 4/121 (3%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
+TINSQP +N +S P GWG GYVYQK YLEF KEKL + + +TY A
Sbjct: 438 ITINSQPQLNGVKSSHPVHGWGPRDGYVYQKMYLEFLLPKEKLSKLHDCLVNDVMLTYFA 497
Query: 197 VNKGEQWVSNTAQAD-VNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAF---ETWSRSWA 30
V+ +N NAVTWG+FP +E++QPTIV+ SF WK E + E W ++
Sbjct: 498 VDHNGNLTTNHQDGTRANAVTWGIFPGREVLQPTIVEKVSFLAWKQEFYHICEEWKLNFI 557
Query: 29 N 27
N
Sbjct: 558 N 558
[137][TOP]
>UniRef100_B2B6X0 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B6X0_PODAN
Length = 691
Score = 101 bits (252), Expect = 2e-20
Identities = 52/137 (37%), Positives = 74/137 (54%), Gaps = 13/137 (9%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCK---ALPSITY 204
++ SQP+VN RS PT GWG G+V+QKA++EFF + +K + + +
Sbjct: 523 SLASQPAVNGLRSSDPTFGWGPANGFVFQKAFVEFFIPSADWKVLEQKLRHPDLKDDVCF 582
Query: 203 MAVNKGEQWVSNTA----------QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAF 54
A+N +VS+ +A NAVTWGVFP KEI+ PTI++ SF W +EAF
Sbjct: 583 YAINAAGDFVSSDTAGSLEAEGEKEASTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAF 642
Query: 53 ETWSRSWANLYPEADPS 3
W WA +Y + S
Sbjct: 643 GIWG-EWAKIYGKGSES 658
[138][TOP]
>UniRef100_B2WHR5 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WHR5_PYRTR
Length = 653
Score = 100 bits (250), Expect = 4e-20
Identities = 49/119 (41%), Positives = 68/119 (57%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAV 195
T+ SQP+VN +S P GWG GYV+QK ++EFF + A K +A +T+ A
Sbjct: 499 TVASQPAVNGVKSTDPIFGWGPKNGYVFQKPFVEFFIPAAEFQAFKPKLQAHDQVTWFAG 558
Query: 194 NKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 18
N + + + + VN VTWG F KEI+ PTI++ SF W DEAF W + W +YP
Sbjct: 559 NAAGAFEA-SQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWLDEAFSIW-KEWQRIYP 615
[139][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 100 bits (250), Expect = 4e-20
Identities = 52/122 (42%), Positives = 71/122 (58%), Gaps = 4/122 (3%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS--ITYM 201
T+ SQP+V+ S VGWG GYV+QK ++EFFC ++ +D + + + + Y
Sbjct: 439 TVGSQPAVDGVSSGDKVVGWGPRGGYVFQKGFVEFFCEEKDMDVIERRVERNGHGWVHYF 498
Query: 200 AVN--KGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWAN 27
A N + SN + NAVTWGVFP +EI Q TI++ SF WKDEAF WS WA+
Sbjct: 499 AGNYKADGECRSNVPEGGRNAVTWGVFPGQEIAQTTIIEKESFLTWKDEAFSIWS-EWAS 557
Query: 26 LY 21
Y
Sbjct: 558 FY 559
[140][TOP]
>UniRef100_C7YTQ6 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YTQ6_NECH7
Length = 674
Score = 100 bits (248), Expect = 7e-20
Identities = 55/137 (40%), Positives = 73/137 (53%), Gaps = 13/137 (9%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKA---LPSITY 204
T+ SQP+VN RS T GWG P G+V+QK+++EFF + + EK + S+ +
Sbjct: 506 TVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFFIPSSEWSVLKEKLNSSELCDSVCF 565
Query: 203 MAVNKGEQWVSNT----------AQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAF 54
A N +VS+ A NAVTWGVFP KEII PTI++ SF W +EAF
Sbjct: 566 YAGNAKGDFVSSDKGGHVDGSSGAGPSTNAVTWGVFPGKEIITPTIIEEVSFRAWCEEAF 625
Query: 53 ETWSRSWANLYPEADPS 3
W WA +Y S
Sbjct: 626 GIWG-EWAKVYGRGSDS 641
[141][TOP]
>UniRef100_Q0CE17 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CE17_ASPTN
Length = 696
Score = 99.8 bits (247), Expect = 9e-20
Identities = 54/140 (38%), Positives = 74/140 (52%), Gaps = 16/140 (11%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKC---KALPSIT 207
T+ SQP+VN RSD P GWG P G+V+QK ++EFFC + ++ +
Sbjct: 512 TLASQPAVNGVRSDDPIFGWGPPREGFVFQKPFVEFFCPTKDYQTALKPMLQKHGHEKLA 571
Query: 206 YMAVNKGEQWVSN----TAQAD--------VNAVTWGVFPAKEIIQPTIVDPASFNVWKD 63
+ A N + S+ T+ AD VNAVTWGVF KEI+ PTI++ SF W D
Sbjct: 572 WFATNANGDFESSLPAQTSDADPIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGD 631
Query: 62 EAFETWSRSWANLYPEADPS 3
EA+ W W +YP P+
Sbjct: 632 EAYRIWD-EWRRIYPRGSPT 650
[142][TOP]
>UniRef100_A1C4Z1 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C4Z1_ASPCL
Length = 690
Score = 99.0 bits (245), Expect = 1e-19
Identities = 57/135 (42%), Positives = 77/135 (57%), Gaps = 16/135 (11%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKCKAL---PSIT 207
T+ SQP+VN RSD+ T GWG P G+V+QK ++EFFC + + V++ A +
Sbjct: 505 TLASQPAVNGVRSDNSTFGWGPPGEGFVFQKPFVEFFCPSKDFETVLKPLFANHGHEKLA 564
Query: 206 YMAVN-KGEQWVS---NTAQAD--------VNAVTWGVFPAKEIIQPTIVDPASFNVWKD 63
+ A N KGE S TA +D VNAVTWGVF KEI+ PTI++ SF W +
Sbjct: 565 WFATNAKGEFQSSLPAETADSDALEPNPDNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGE 624
Query: 62 EAFETWSRSWANLYP 18
EA+ W W +YP
Sbjct: 625 EAYRIW-EEWRRIYP 638
[143][TOP]
>UniRef100_Q7S2B6 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S2B6_NEUCR
Length = 681
Score = 98.6 bits (244), Expect = 2e-19
Identities = 56/143 (39%), Positives = 77/143 (53%), Gaps = 25/143 (17%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEK---LDAVVEKCKALPSITY 204
++ SQP+VN RSD T GWG G+V+QKA++EFF L+A +++ ++ +
Sbjct: 501 SLASQPAVNGLRSDDGTFGWGPENGFVFQKAFVEFFIPSADWRVLEAKLKQPDMKDTVCF 560
Query: 203 MAVNKGEQWVSN---------------TAQAD-------VNAVTWGVFPAKEIIQPTIVD 90
A N +VS TA+AD NAVTWGVFP KEI+ PTI++
Sbjct: 561 FATNAAGDFVSTDTINFRARMAAEAEGTAEADHRPHEPSTNAVTWGVFPGKEILTPTIIE 620
Query: 89 PASFNVWKDEAFETWSRSWANLY 21
SF W +EAF WS WA +Y
Sbjct: 621 EVSFRAWSEEAFGIWS-EWAKIY 642
[144][TOP]
>UniRef100_Q752W6 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q752W6_ASHGO
Length = 635
Score = 98.2 bits (243), Expect = 3e-19
Identities = 50/126 (39%), Positives = 70/126 (55%), Gaps = 2/126 (1%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS--ITY 204
LT+ SQP+ N+ S GWG P G VYQKA++E F K + +A ++ P +Y
Sbjct: 477 LTLASQPATNSTPSADKIFGWGPPGGVVYQKAFVELFVEKARWEAELKPRLEGPDSKFSY 536
Query: 203 MAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANL 24
+ + SN A + VTWGVFP +I+Q TI++ SF W+DEAF W SW+ L
Sbjct: 537 YFGDSAGSFASNMAPESSSVVTWGVFPNSQILQTTIIEEESFKAWRDEAFSIW-LSWSKL 595
Query: 23 YPEADP 6
+P P
Sbjct: 596 FPRNSP 601
[145][TOP]
>UniRef100_A7TRT4 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TRT4_VANPO
Length = 645
Score = 98.2 bits (243), Expect = 3e-19
Identities = 54/128 (42%), Positives = 71/128 (55%), Gaps = 3/128 (2%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVE-KCKALP--SIT 207
LT+ SQP+ NA S GWG GYVYQKA++E F K++ +A+V+ K P +
Sbjct: 486 LTLASQPATNASPSTDKIFGWGPKNGYVYQKAFVEMFILKKQWEAIVKPKLDHYPRGKFS 545
Query: 206 YMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWAN 27
Y + + SN N VTWGVFP +IQ TIV+ SF W+DEAF W WA
Sbjct: 546 YYVGDSSGSFESNLETNSSNVVTWGVFPNSPVIQTTIVEEESFKAWRDEAFCIW-LEWAK 604
Query: 26 LYPEADPS 3
L+P + S
Sbjct: 605 LFPSNELS 612
[146][TOP]
>UniRef100_UPI000023F2EE hypothetical protein FG07127.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023F2EE
Length = 672
Score = 97.8 bits (242), Expect = 3e-19
Identities = 55/137 (40%), Positives = 72/137 (52%), Gaps = 13/137 (9%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSK---EKLDAVVEKCKALPSITY 204
T+ SQP+VN RS T GWG P G+V+QK+++EFF E L A + + + +
Sbjct: 504 TVASQPAVNGLRSSDATFGWGPPNGFVFQKSFVEFFIPANEWEILKAKLVSSELQDYVCF 563
Query: 203 MAVNKGEQWVSNT----------AQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAF 54
A N +VS+ A NAVTWGVFP KEII PTI++ SF W +EAF
Sbjct: 564 YASNARGDYVSSDIGGHVDGSTEASPSTNAVTWGVFPGKEIITPTIIEEVSFRAWCEEAF 623
Query: 53 ETWSRSWANLYPEADPS 3
W WA +Y S
Sbjct: 624 GIWG-EWAKVYGRGSES 639
[147][TOP]
>UniRef100_Q5A5S8 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5A5S8_CANAL
Length = 640
Score = 97.8 bits (242), Expect = 3e-19
Identities = 50/129 (38%), Positives = 72/129 (55%), Gaps = 5/129 (3%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAV 195
++ SQP+VN +S GWG G +YQK+++E F KE ++ K + ++TY
Sbjct: 479 SVASQPAVNGCKSTDNIFGWGPRNGIIYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVG 538
Query: 194 NKGEQWVSN-----TAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWA 30
NK + SN + NAVTWGVFP+KE++QPT++D SF W +EAF W WA
Sbjct: 539 NKDGEIKSNLPIGPNVKLSKNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFLLW-LEWA 597
Query: 29 NLYPEADPS 3
Y + S
Sbjct: 598 RCYKKNSKS 606
[148][TOP]
>UniRef100_Q2HBA5 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2HBA5_CHAGB
Length = 643
Score = 97.8 bits (242), Expect = 3e-19
Identities = 49/124 (39%), Positives = 68/124 (54%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAV 195
T+ SQP+VN RS PT GWG G+V+QKA++EFF A+ ++ +
Sbjct: 505 TLASQPAVNGLRSSDPTFGWGPQNGFVFQKAFVEFFLPLADWAALEKR-----------L 553
Query: 194 NKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPE 15
N+ E +A NAV+WGVFP KEI+ PTI++ SF W +EAF W W +Y +
Sbjct: 554 NRPEMEGRREREASTNAVSWGVFPGKEIVPPTIIEEVSFRAWSEEAFGIWG-EWVKIYEK 612
Query: 14 ADPS 3
S
Sbjct: 613 GSES 616
[149][TOP]
>UniRef100_C4YKV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=C4YKV3_CANAL
Length = 640
Score = 97.8 bits (242), Expect = 3e-19
Identities = 50/129 (38%), Positives = 72/129 (55%), Gaps = 5/129 (3%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAV 195
++ SQP+VN +S GWG G +YQK+++E F KE ++ K + ++TY
Sbjct: 479 SVASQPAVNGCKSTDNIFGWGPRNGIIYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVG 538
Query: 194 NKGEQWVSN-----TAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWA 30
NK + SN + NAVTWGVFP+KE++QPT++D SF W +EAF W WA
Sbjct: 539 NKDGEIKSNLPIGPNVKLSKNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFLLW-LEWA 597
Query: 29 NLYPEADPS 3
Y + S
Sbjct: 598 RCYKKNSKS 606
[150][TOP]
>UniRef100_Q6CEM7 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CEM7_YARLI
Length = 625
Score = 97.4 bits (241), Expect = 4e-19
Identities = 50/119 (42%), Positives = 70/119 (58%), Gaps = 1/119 (0%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAV 195
T+ SQP+ NA +SD GWG GYV+QK++ EFF S E+ + A + V
Sbjct: 468 TVASQPACNALKSDDNIFGWGPKGGYVFQKSFAEFFISPEQWKKLKPLLDAQEDLVSYYV 527
Query: 194 NKGEQWV-SNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
K ++ V +N ++ N VTWGVFP +EI+Q TI+ SF+ W++EAF WS W LY
Sbjct: 528 AKSDKLVDTNVSERASNGVTWGVFPNREIVQTTIIQEDSFDAWREEAFSIWS-EWRALY 585
[151][TOP]
>UniRef100_C5DIA7 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5DIA7_LACTC
Length = 660
Score = 97.4 bits (241), Expect = 4e-19
Identities = 48/122 (39%), Positives = 74/122 (60%), Gaps = 2/122 (1%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVE-KCKALPS-ITY 204
L++ SQP+ N+ S GWG P GYVYQK+++E F K++ + ++ K + L S ++Y
Sbjct: 502 LSLASQPATNSTPSTDKIFGWGPPGGYVYQKSFVEMFVHKQQWELEIKPKLEPLGSKVSY 561
Query: 203 MAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANL 24
+ E + +N + + VTWGVFP E++Q TIV+ SF W+DEAF W W+ L
Sbjct: 562 YVGDSAETFYTNLDSSCSSVVTWGVFPNSEVLQTTIVEEESFKAWRDEAFSIW-LEWSKL 620
Query: 23 YP 18
+P
Sbjct: 621 FP 622
[152][TOP]
>UniRef100_Q6FNS2 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FNS2_CANGA
Length = 645
Score = 97.1 bits (240), Expect = 6e-19
Identities = 49/128 (38%), Positives = 69/128 (53%), Gaps = 3/128 (2%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEK---CKALPSIT 207
LT+ SQP NA S GWG G+VYQKA++E F +++ +++ +
Sbjct: 486 LTLASQPCTNASSSTDKIFGWGPSKGHVYQKAFIEMFVHRQQWKTILKPKLDYYGRRKFS 545
Query: 206 YMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWAN 27
Y A + + +N N VTWGVFP ++IQ TI++ SF W+DEAF WS WA
Sbjct: 546 YYAGDSKGSFETNLDPHSSNVVTWGVFPNSQVIQTTIIEEESFKAWRDEAFSIWS-EWAK 604
Query: 26 LYPEADPS 3
L+P PS
Sbjct: 605 LFPRNTPS 612
[153][TOP]
>UniRef100_Q2UA39 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus oryzae
RepID=Q2UA39_ASPOR
Length = 690
Score = 97.1 bits (240), Expect = 6e-19
Identities = 54/135 (40%), Positives = 73/135 (54%), Gaps = 16/135 (11%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKC---KALPSIT 207
T+ SQP+VN RSD P GWG P G+V+QK ++EFFC + ++++ +
Sbjct: 504 TLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLLQKHGHEKLA 563
Query: 206 YMAVN-KGEQWVSNTAQA-----------DVNAVTWGVFPAKEIIQPTIVDPASFNVWKD 63
+ A N KG+ S AQ +VN VTWGVF KEI+ PTI++ SF W D
Sbjct: 564 WFAANVKGDFESSLPAQTSDADPIEMNPNNVNCVTWGVFRGKEIVTPTIIEEVSFRAWGD 623
Query: 62 EAFETWSRSWANLYP 18
EAF W W +YP
Sbjct: 624 EAFRIWD-EWRRIYP 637
[154][TOP]
>UniRef100_B8NQE8 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus flavus
NRRL3357 RepID=B8NQE8_ASPFN
Length = 738
Score = 97.1 bits (240), Expect = 6e-19
Identities = 54/135 (40%), Positives = 73/135 (54%), Gaps = 16/135 (11%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKC---KALPSIT 207
T+ SQP+VN RSD P GWG P G+V+QK ++EFFC + ++++ +
Sbjct: 552 TLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLLQKHGHEKLA 611
Query: 206 YMAVN-KGEQWVSNTAQA-----------DVNAVTWGVFPAKEIIQPTIVDPASFNVWKD 63
+ A N KG+ S AQ +VN VTWGVF KEI+ PTI++ SF W D
Sbjct: 612 WFAANVKGDFESSLPAQTSDADPIEMNPNNVNCVTWGVFRGKEIVTPTIIEEVSFRAWGD 671
Query: 62 EAFETWSRSWANLYP 18
EAF W W +YP
Sbjct: 672 EAFRIWD-EWRRIYP 685
[155][TOP]
>UniRef100_Q1DT03 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DT03_COCIM
Length = 711
Score = 96.3 bits (238), Expect = 1e-18
Identities = 55/152 (36%), Positives = 76/152 (50%), Gaps = 28/152 (18%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKCKAL---PSIT 207
TI SQP+V+ RSD P GWG P G+V+QKA++EFFCSK+ + ++
Sbjct: 510 TIASQPAVSGVRSDHPIFGWGPPGEGFVFQKAFVEFFCSKDDYRSHLKPLLQRYGHDEFA 569
Query: 206 YMAVNKGEQWVSNTAQA------------------------DVNAVTWGVFPAKEIIQPT 99
+ A N + S+T+ + VNAVTWGVF KEII PT
Sbjct: 570 WFATNAAGDFESSTSSSIPVPTGPVDAVFDDMDSFPSSNSGGVNAVTWGVFRGKEIITPT 629
Query: 98 IVDPASFNVWKDEAFETWSRSWANLYPEADPS 3
I++ SF W +EAF W W ++P P+
Sbjct: 630 IIEEVSFRAWGEEAFRIWD-EWRRIFPRGSPT 660
[156][TOP]
>UniRef100_B9WCV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WCV3_CANDC
Length = 640
Score = 96.3 bits (238), Expect = 1e-18
Identities = 49/129 (37%), Positives = 73/129 (56%), Gaps = 5/129 (3%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAV 195
++ SQP++N +S GWG G +YQK+++E F KE ++ K + ++TY
Sbjct: 479 SVASQPAINGCKSTDNIFGWGPRNGTIYQKSFIELFMPKEDWTKLLLKIELDKTVTYYVG 538
Query: 194 NKGEQWVSN-----TAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWA 30
+K + SN A+ NAVTWGVFP+KE++QPT++D SF W +EAF W WA
Sbjct: 539 DKDGEIRSNLPIGPNAKLSKNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFLLWV-EWA 597
Query: 29 NLYPEADPS 3
Y + S
Sbjct: 598 RCYKKNSKS 606
[157][TOP]
>UniRef100_C1H0K0 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1H0K0_PARBA
Length = 713
Score = 95.9 bits (237), Expect = 1e-18
Identities = 53/147 (36%), Positives = 76/147 (51%), Gaps = 23/147 (15%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVE---KCKALPSIT 207
T+ SQP+VN RSD P GWG G+V+QKA++EFFCS + + +++ K ++
Sbjct: 512 TLASQPAVNGVRSDHPIFGWGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELS 571
Query: 206 YMAVNKGEQWVSNTA-------------------QADVNAVTWGVFPAKEIIQPTIVDPA 84
+ A N + S+++ VNAVTWGVF KEII PTI++
Sbjct: 572 WFATNASGDFQSSSSFTGITGLDDAVPDYNGAASSNGVNAVTWGVFKGKEIITPTIIEEV 631
Query: 83 SFNVWKDEAFETWSRSWANLYPEADPS 3
SF W DEAF W W ++ P+
Sbjct: 632 SFRAWGDEAFRIWD-EWRRIFRRGSPT 657
[158][TOP]
>UniRef100_C8V780 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5AU15] n=2 Tax=Emericella
nidulans RepID=C8V780_EMENI
Length = 684
Score = 95.5 bits (236), Expect = 2e-18
Identities = 53/138 (38%), Positives = 74/138 (53%), Gaps = 17/138 (12%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGP-VGYVYQKAYLEFFCS----KEKLDAVVEKCKALPSI 210
T+ SQP+VN RSD P GWG P G+V+QK ++EFFC K L +++K +
Sbjct: 500 TLASQPAVNGVRSDDPIFGWGPPGEGFVFQKPFVEFFCPASDFKTTLKPLLQK-HGHEKL 558
Query: 209 TYMAVNKGEQWVSNTAQA------------DVNAVTWGVFPAKEIIQPTIVDPASFNVWK 66
+ A N + S+ +VNAVTWGVF KEI+ PTI++ SF W
Sbjct: 559 AWFATNAAGDFESSLPAETSDTEPVEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWG 618
Query: 65 DEAFETWSRSWANLYPEA 12
DEA+ W W +YP++
Sbjct: 619 DEAYRIWD-EWRRIYPKS 635
[159][TOP]
>UniRef100_C5P4Q4 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5P4Q4_COCP7
Length = 711
Score = 95.5 bits (236), Expect = 2e-18
Identities = 54/152 (35%), Positives = 76/152 (50%), Gaps = 28/152 (18%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKCKAL---PSIT 207
T+ SQP+V+ RSD P GWG P G+V+QKA++EFFCSK+ + ++
Sbjct: 510 TLASQPAVSGVRSDHPIFGWGPPGEGFVFQKAFVEFFCSKDDYRSHLKPLLQRYGHDEFA 569
Query: 206 YMAVNKGEQWVSNTAQA------------------------DVNAVTWGVFPAKEIIQPT 99
+ A N + S+T+ + VNAVTWGVF KEII PT
Sbjct: 570 WFATNAAGDFESSTSSSIPVPTGPVDAVFDDMDSFPSSNSGGVNAVTWGVFRGKEIITPT 629
Query: 98 IVDPASFNVWKDEAFETWSRSWANLYPEADPS 3
I++ SF W +EAF W W ++P P+
Sbjct: 630 IIEEVSFRAWGEEAFRIWD-EWRRIFPRGSPT 660
[160][TOP]
>UniRef100_B6HK87 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6HK87_PENCW
Length = 691
Score = 95.5 bits (236), Expect = 2e-18
Identities = 55/142 (38%), Positives = 74/142 (52%), Gaps = 18/142 (12%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKCKAL---PSIT 207
T+ SQP+VN +D P GWG G+V+QK ++EFFCS +++ A +T
Sbjct: 503 TLASQPAVNGVHNDHPIFGWGPQREGFVFQKPFVEFFCSSNDYTNILKPLFAKHGHDKLT 562
Query: 206 YMAVN-KGEQWVSNTAQA-------------DVNAVTWGVFPAKEIIQPTIVDPASFNVW 69
+ A N KG+ S AQ VNAVTWGVF KEI+ PTI++ SF W
Sbjct: 563 WFATNVKGDFESSLPAQPADMDLDDLGSNPESVNAVTWGVFRGKEIVTPTIIEEVSFRAW 622
Query: 68 KDEAFETWSRSWANLYPEADPS 3
+EAF W W +YP P+
Sbjct: 623 GEEAFRIWD-EWRRIYPRGSPT 643
[161][TOP]
>UniRef100_C4R2L4 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2L4_PICPG
Length = 596
Score = 95.1 bits (235), Expect = 2e-18
Identities = 49/122 (40%), Positives = 70/122 (57%), Gaps = 2/122 (1%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKL-DAVVEKCKALPSITYMA 198
TI+SQPS N +S GWG GYVYQKA++E F +K++ + ++ + S+T+
Sbjct: 438 TISSQPSANGVKSTDKLFGWGPSEGYVYQKAFVEVFINKKQWNEEILPNLQGHKSVTWYL 497
Query: 197 VNKGEQWVSNTA-QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
+ + +N N+VTWG FP KEI+Q TI+ SF W +EAF W R W LY
Sbjct: 498 GDCNNAFDTNIKIPLSSNSVTWGCFPDKEIVQTTIIGEESFQAWNEEAFNIW-REWQKLY 556
Query: 20 PE 15
P+
Sbjct: 557 PK 558
[162][TOP]
>UniRef100_A7E9M9 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7E9M9_SCLS1
Length = 663
Score = 95.1 bits (235), Expect = 2e-18
Identities = 50/122 (40%), Positives = 70/122 (57%), Gaps = 4/122 (3%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKA---LPSITY 204
T+ SQP+VN +S GWG G+V+QKA++E F +A+ K + ++++
Sbjct: 504 TVASQPAVNGVKSTDSIFGWGPKNGFVFQKAFVELFLPTSDWEALQAKLTSPALRDTVSF 563
Query: 203 MAVN-KGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWAN 27
A N KG+ S+ A NAVTWG FP KEII PTI++ SF W +EAF W WA
Sbjct: 564 YASNAKGDFISSDEAIGSTNAVTWGAFPGKEIITPTIIEEVSFRAWAEEAFGIWG-EWAR 622
Query: 26 LY 21
+Y
Sbjct: 623 VY 624
[163][TOP]
>UniRef100_A5DE00 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DE00_PICGU
Length = 642
Score = 94.7 bits (234), Expect = 3e-18
Identities = 53/127 (41%), Positives = 72/127 (56%), Gaps = 9/127 (7%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDA-VVEKCKALPS---IT 207
++ SQPSVN RS GWG G+V+QK+++E F KE+ + K K + IT
Sbjct: 478 SLASQPSVNGARSSDKIFGWGPSNGFVFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDIT 537
Query: 206 YMAVNKGEQWVSNT-----AQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWS 42
Y A + + SN + NAVTWGVFP++E++QPTI+D SF W +EAF WS
Sbjct: 538 YYAGDSSGKIQSNLPVGPDSHNSKNAVTWGVFPSQEVLQPTIIDIESFRAWNEEAFHLWS 597
Query: 41 RSWANLY 21
WA Y
Sbjct: 598 -EWARCY 603
[164][TOP]
>UniRef100_A2QUJ5 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QUJ5_ASPNC
Length = 699
Score = 94.7 bits (234), Expect = 3e-18
Identities = 55/137 (40%), Positives = 74/137 (54%), Gaps = 17/137 (12%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKC---KALPSIT 207
T+ SQP++N RSD P GWG P G+V+QK ++EFFC + V++ +
Sbjct: 513 TLASQPAINGVRSDDPVFGWGPPGEGFVFQKPFVEFFCPTKDYLTVLKPLLQKHGHEKLA 572
Query: 206 YMAVN-KGEQWVS----NTAQAD--------VNAVTWGVFPAKEIIQPTIVDPASFNVWK 66
+ A N KG+ S NT D VNAVTWGVF KEI+ PTI++ SF W
Sbjct: 573 WFATNVKGDFESSLPGPNTDDPDPIDINPANVNAVTWGVFRGKEIVTPTIIEEVSFRAWG 632
Query: 65 DEAFETWSRSWANLYPE 15
DEA+ W W +YP+
Sbjct: 633 DEAYRIWD-EWRRIYPK 648
[165][TOP]
>UniRef100_C5M548 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M548_CANTT
Length = 633
Score = 94.4 bits (233), Expect = 4e-18
Identities = 51/129 (39%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAV 195
++ SQP+ NA +S GWG G VYQKA++E F K+ + + +A SITY A
Sbjct: 472 SVASQPAANACKSTDNIFGWGPRNGVVYQKAFVELFMPKDDWNKLKPLVEASDSITYYAA 531
Query: 194 NKGEQWVSNT-AQADV----NAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWA 30
+K + + A D+ NAVTWGVFP+KE++QPT++D SF W +E+F W W+
Sbjct: 532 DKTNKIEAKVPAGHDIKLTKNAVTWGVFPSKEVLQPTVIDYESFKAWNEESFLLW-LEWS 590
Query: 29 NLYPEADPS 3
Y + S
Sbjct: 591 RCYKKNSKS 599
[166][TOP]
>UniRef100_C5GI01 Methylenetetrahydrofolate reductase n=2 Tax=Ajellomyces
dermatitidis RepID=C5GI01_AJEDR
Length = 713
Score = 94.4 bits (233), Expect = 4e-18
Identities = 52/152 (34%), Positives = 74/152 (48%), Gaps = 28/152 (18%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKC---KALPSIT 207
T+ SQP+VN R+D P GWG G+V+QKA++EFFC+ L +++ +
Sbjct: 508 TLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAFVEFFCTAHDLKTILKPIFENHGHDELA 567
Query: 206 YMAVNKGEQWVSNTAQAD------------------------VNAVTWGVFPAKEIIQPT 99
+ A N + S++ D VNAVTWGVF KEI+ PT
Sbjct: 568 WFATNAAGDFESSSPPTDDSANDYSGPVDVYLDSNATAGGTGVNAVTWGVFRGKEIVTPT 627
Query: 98 IVDPASFNVWKDEAFETWSRSWANLYPEADPS 3
I++ SF W DEAF W W ++P P+
Sbjct: 628 IIEEVSFRAWGDEAFRIWD-EWRRVFPRGSPT 658
[167][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 94.0 bits (232), Expect = 5e-18
Identities = 48/121 (39%), Positives = 72/121 (59%), Gaps = 2/121 (1%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS-ITYMA 198
T+ SQP+V+ S PT G+G GY++QKA++E F ++ +A+V+ + + +TY A
Sbjct: 430 TVGSQPAVDGCDSTDPTFGFGPQGGYIFQKAFVELFMNENDKNALVQMIQGSSTPVTYFA 489
Query: 197 VN-KGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 21
+ +N +N VTWGVFP E+ Q TI++ ASF W+DEAF W R W L+
Sbjct: 490 GKCDPTTFETNLTTNGLNTVTWGVFPGTEVAQSTIIEEASFRAWRDEAFAIW-REWELLF 548
Query: 20 P 18
P
Sbjct: 549 P 549
[168][TOP]
>UniRef100_A6RQJ7 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6RQJ7_BOTFB
Length = 663
Score = 94.0 bits (232), Expect = 5e-18
Identities = 50/122 (40%), Positives = 69/122 (56%), Gaps = 4/122 (3%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFF---CSKEKLDAVVEKCKALPSITY 204
T+ SQP+VN +S GWG G+V+QKA++E F + L A + ++++
Sbjct: 504 TVASQPAVNGLKSSDSIFGWGPKNGFVFQKAFVELFIPVADWKTLHAKLTSPDLCDTVSF 563
Query: 203 MAVN-KGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWAN 27
A N KG+ S+ A NAVTWG FP KEII PTI++ SF W +EAF W WA
Sbjct: 564 YASNAKGDFISSDEAVGSTNAVTWGAFPGKEIITPTIIEEVSFRAWAEEAFGIWG-EWAR 622
Query: 26 LY 21
+Y
Sbjct: 623 VY 624
[169][TOP]
>UniRef100_C4Y9Q4 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y9Q4_CLAL4
Length = 601
Score = 93.2 bits (230), Expect = 8e-18
Identities = 49/129 (37%), Positives = 75/129 (58%), Gaps = 5/129 (3%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSK---EKLDAVVEKCKALPSITY 204
T+ SQP+V++ S +GWG G ++QK+++EFF K E+L +++K + +ITY
Sbjct: 441 TLASQPAVDSCPSSDSILGWGPRNGRIFQKSFVEFFVPKTEWERLLRLMDKDISDKTITY 500
Query: 203 MAVNKGEQWVSNTAQ--ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWA 30
N + +N + A+TWGVFP+KE++QPT++D SF W +EAF W WA
Sbjct: 501 FCGNSKGEITTNMPHKSSQRTAITWGVFPSKEVLQPTVIDRQSFQAWNEEAFGLW-LDWA 559
Query: 29 NLYPEADPS 3
Y PS
Sbjct: 560 RCYAPDSPS 568
[170][TOP]
>UniRef100_C1GJU2 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1GJU2_PARBD
Length = 712
Score = 93.2 bits (230), Expect = 8e-18
Identities = 52/147 (35%), Positives = 75/147 (51%), Gaps = 23/147 (15%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVE---KCKALPSIT 207
T+ SQP+VN RSD P GWG G+V+QKA++EFFCS + + +++ K ++
Sbjct: 512 TLASQPAVNGVRSDHPIFGWGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELS 571
Query: 206 YMAVNKGEQWVSNTA-------------------QADVNAVTWGVFPAKEIIQPTIVDPA 84
+ A N + S+++ VNAVTWGVF KEII PTI++
Sbjct: 572 WFATNASGDFQSSSSFTGTTGLDDAVPDYNGAASSNGVNAVTWGVFKGKEIITPTIIEEV 631
Query: 83 SFNVWKDEAFETWSRSWANLYPEADPS 3
SF W EAF W W ++ P+
Sbjct: 632 SFRAWGHEAFRIWD-EWRRIFRRGSPT 657
[171][TOP]
>UniRef100_C0S8C4 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0S8C4_PARBP
Length = 712
Score = 93.2 bits (230), Expect = 8e-18
Identities = 52/147 (35%), Positives = 75/147 (51%), Gaps = 23/147 (15%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVE---KCKALPSIT 207
T+ SQP+VN RSD P GWG G+V+QKA++EFFCS + + +++ K ++
Sbjct: 512 TLASQPAVNGVRSDHPIFGWGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELS 571
Query: 206 YMAVNKGEQWVSNTA-------------------QADVNAVTWGVFPAKEIIQPTIVDPA 84
+ A N + S+++ VNAVTWGVF KEII PTI++
Sbjct: 572 WFATNASGDFQSSSSFTGTTGLDDAVPDYSGAASSNGVNAVTWGVFKGKEIITPTIIEEV 631
Query: 83 SFNVWKDEAFETWSRSWANLYPEADPS 3
SF W EAF W W ++ P+
Sbjct: 632 SFRAWGHEAFRIWD-EWRRIFRRGSPT 657
[172][TOP]
>UniRef100_C0NTN2 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NTN2_AJECG
Length = 713
Score = 93.2 bits (230), Expect = 8e-18
Identities = 50/152 (32%), Positives = 75/152 (49%), Gaps = 28/152 (18%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVE---KCKALPSIT 207
T+ SQP+VN R+D P GWG G+V+QKA++EFFC +++++ + +
Sbjct: 508 TLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFA 567
Query: 206 YMAVNKGEQWVSNTAQAD------------------------VNAVTWGVFPAKEIIQPT 99
+ A N ++S++ D V AVTWGVF KEI+ PT
Sbjct: 568 WFATNAAGDFMSSSPATDATTEDSSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPT 627
Query: 98 IVDPASFNVWKDEAFETWSRSWANLYPEADPS 3
I++ SF W DEAF W W ++P P+
Sbjct: 628 IIEEVSFRAWGDEAFRIWD-EWRRIFPRGSPT 658
[173][TOP]
>UniRef100_A6QT35 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6QT35_AJECN
Length = 712
Score = 93.2 bits (230), Expect = 8e-18
Identities = 50/152 (32%), Positives = 75/152 (49%), Gaps = 28/152 (18%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVE---KCKALPSIT 207
T+ SQP+VN R+D P GWG G+V+QKA++EFFC +++++ + +
Sbjct: 507 TLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFA 566
Query: 206 YMAVNKGEQWVSNTAQAD------------------------VNAVTWGVFPAKEIIQPT 99
+ A N ++S++ D V AVTWGVF KEI+ PT
Sbjct: 567 WFATNAAGDFMSSSPATDAATEDFSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPT 626
Query: 98 IVDPASFNVWKDEAFETWSRSWANLYPEADPS 3
I++ SF W DEAF W W ++P P+
Sbjct: 627 IIEEVSFRAWGDEAFRIWD-EWRRIFPRGSPT 657
[174][TOP]
>UniRef100_A4RH85 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RH85_MAGGR
Length = 662
Score = 93.2 bits (230), Expect = 8e-18
Identities = 53/147 (36%), Positives = 74/147 (50%), Gaps = 23/147 (15%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSIT-YMA 198
T+ SQP+VN RS+ T GWG G+V+QKA++E F + A+ EK + + + A
Sbjct: 484 TVASQPAVNGLRSNDRTFGWGPQNGFVFQKAFVEMFLPSKDWKALREKLLSEKDVVCFYA 543
Query: 197 VNKGEQWVSNTAQADV----------------------NAVTWGVFPAKEIIQPTIVDPA 84
N + S+ D NAVTWGVFP KEI+ PTI++
Sbjct: 544 SNAKGDFESSDGGGDAPDGAPTGNGFADEQPLPSGSSTNAVTWGVFPGKEIVTPTIIEEV 603
Query: 83 SFNVWKDEAFETWSRSWANLYPEADPS 3
SF W +EAF W+ WA +Y + PS
Sbjct: 604 SFRAWSEEAFGIWA-EWAKVYGKDSPS 629
[175][TOP]
>UniRef100_C6HED8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6HED8_AJECH
Length = 713
Score = 92.8 bits (229), Expect = 1e-17
Identities = 50/152 (32%), Positives = 75/152 (49%), Gaps = 28/152 (18%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVE---KCKALPSIT 207
T+ SQP+VN R+D P GWG G+V+QKA++EFFC +++++ + +
Sbjct: 508 TLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFA 567
Query: 206 YMAVNKGEQWVSNTAQAD------------------------VNAVTWGVFPAKEIIQPT 99
+ A N ++S++ D V AVTWGVF KEI+ PT
Sbjct: 568 WFATNVAGDFMSSSPATDATTEDSSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPT 627
Query: 98 IVDPASFNVWKDEAFETWSRSWANLYPEADPS 3
I++ SF W DEAF W W ++P P+
Sbjct: 628 IIEEVSFRAWGDEAFRIWD-EWRRIFPRGSPT 658
[176][TOP]
>UniRef100_Q6CR34 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CR34_KLULA
Length = 649
Score = 92.0 bits (227), Expect = 2e-17
Identities = 48/126 (38%), Positives = 72/126 (57%), Gaps = 2/126 (1%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVE-KCKALPS-ITY 204
L++ SQP+ N +S GWG G +YQKA++E F KE+ + V++ K ++ +Y
Sbjct: 491 LSLASQPATNGSQSTDNIFGWGPANGLIYQKAFVEIFVRKEEWNQVLKPKIESKNGEFSY 550
Query: 203 MAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANL 24
+ + +N NAVTWGVFP E++Q TIV+ SF W+DEAF W W+ L
Sbjct: 551 YLGDYTGYFETNLQPKSSNAVTWGVFPNSEVVQTTIVEEESFKAWRDEAFSIWI-EWSKL 609
Query: 23 YPEADP 6
+P+ P
Sbjct: 610 FPKNTP 615
[177][TOP]
>UniRef100_UPI000151A866 hypothetical protein PGUG_01501 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151A866
Length = 642
Score = 91.7 bits (226), Expect = 2e-17
Identities = 52/127 (40%), Positives = 70/127 (55%), Gaps = 9/127 (7%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDA-VVEKCKALPS---IT 207
++ SQPSVN RS GWG G+V+QK+++E F KE+ + K K + IT
Sbjct: 478 SLASQPSVNGARSSDKIFGWGPSNGFVFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDIT 537
Query: 206 YMAVNKGEQWVSNT-----AQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWS 42
Y A + + SN + NAVTWGVFP +E++QPTI+D SF W +EAF W
Sbjct: 538 YYAGDSSGKIQSNLPVGPDSHNSKNAVTWGVFPLQEVLQPTIIDIESFRAWNEEAFHLW- 596
Query: 41 RSWANLY 21
WA Y
Sbjct: 597 LEWARCY 603
[178][TOP]
>UniRef100_C4JM22 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JM22_UNCRE
Length = 709
Score = 89.7 bits (221), Expect = 9e-17
Identities = 52/152 (34%), Positives = 72/152 (47%), Gaps = 28/152 (18%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKCKAL---PSIT 207
T+ SQP+VN RSD T GWG P G+V+QKA++EFFCS + ++
Sbjct: 508 TLASQPAVNGVRSDDTTFGWGPPGEGFVFQKAFVEFFCSSNDYRSYLKPLLQRYGHDEFA 567
Query: 206 YMAVNKGEQWVSNTAQA------------------------DVNAVTWGVFPAKEIIQPT 99
+ A N + ++T + VNAVTWGVF KEII PT
Sbjct: 568 WFATNAAGDFEASTPPSAHSPTEPVDAGFEDPSSPAASNPGGVNAVTWGVFRGKEIITPT 627
Query: 98 IVDPASFNVWKDEAFETWSRSWANLYPEADPS 3
I++ SF W +EAF W W ++ P+
Sbjct: 628 IIEEVSFRAWGEEAFRIWD-EWRRIFARGSPT 658
[179][TOP]
>UniRef100_A3LW82 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LW82_PICST
Length = 635
Score = 89.7 bits (221), Expect = 9e-17
Identities = 51/128 (39%), Positives = 71/128 (55%), Gaps = 10/128 (7%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-----SI 210
++ SQP+VN +S GWG G VYQKA++E F KE+ ++ + K P +I
Sbjct: 471 SLASQPAVNGCKSTDRIFGWGPKNGIVYQKAFVEIFVPKEQWESEL-KSSLKPHFEEKTI 529
Query: 209 TYMAVN-----KGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETW 45
TY + + +V A NA+TWGVFP+KE++QPTI+D SF W +EAF W
Sbjct: 530 TYYVGDAEGNIESNLFVGPDAHNSKNAITWGVFPSKEVLQPTIIDYESFKAWNEEAFLLW 589
Query: 44 SRSWANLY 21
WA Y
Sbjct: 590 I-EWARCY 596
[180][TOP]
>UniRef100_C9S8T9 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S8T9_9PEZI
Length = 670
Score = 89.0 bits (219), Expect = 2e-16
Identities = 48/130 (36%), Positives = 67/130 (51%), Gaps = 12/130 (9%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKC---KALPSITY 204
T+ SQP+VN S T GWG G+V+QKA++E F + E+ + ++ +
Sbjct: 503 TVASQPAVNGVPSRDATFGWGPSHGFVFQKAFVELFLPAADWKVLSERLTGPEVEGTVCF 562
Query: 203 MAVNKGEQW---------VSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFE 51
A N + V A NAVTWGVFP KEII PTI++ SF W +EAF+
Sbjct: 563 YACNGNGDFATSDDSGGLVRTAVPASTNAVTWGVFPGKEIITPTIIEEVSFRAWSEEAFK 622
Query: 50 TWSRSWANLY 21
W W+ +Y
Sbjct: 623 IWG-EWSRVY 631
[181][TOP]
>UniRef100_C7GU28 Met12p n=2 Tax=Saccharomyces cerevisiae RepID=C7GU28_YEAS2
Length = 657
Score = 87.8 bits (216), Expect = 3e-16
Identities = 45/128 (35%), Positives = 67/128 (52%), Gaps = 3/128 (2%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCK---ALPSIT 207
LT+ SQP+ NA S GWG G +YQKA++E F +++ + ++ +
Sbjct: 496 LTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFS 555
Query: 206 YMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWAN 27
Y A + + +N + VTWGVFP + Q TI++ SF W+DEAF WS WA
Sbjct: 556 YYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAK 614
Query: 26 LYPEADPS 3
L+P P+
Sbjct: 615 LFPRNTPA 622
[182][TOP]
>UniRef100_C5DPF1 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5DPF1_ZYGRC
Length = 650
Score = 87.8 bits (216), Expect = 3e-16
Identities = 48/125 (38%), Positives = 63/125 (50%), Gaps = 5/125 (4%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKE-----KLDAVVEKCKALPS 213
LT+ SQP+ N S + GWG G VYQKA++E F K + +E+
Sbjct: 490 LTLASQPATNGSPSTNKIFGWGPAYGVVYQKAFIEMFVPKNIWENGNMKKAIEQY-GRAK 548
Query: 212 ITYMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSW 33
+TY A + + +N N VTWGVF ++IQ TIV SF W DEAF W W
Sbjct: 549 LTYYANDSQGNFETNLESNSSNVVTWGVFSDSQVIQSTIVSEESFKAWSDEAFSIW-LEW 607
Query: 32 ANLYP 18
A L+P
Sbjct: 608 AKLFP 612
[183][TOP]
>UniRef100_B5VTD9 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VTD9_YEAS6
Length = 657
Score = 87.8 bits (216), Expect = 3e-16
Identities = 45/128 (35%), Positives = 67/128 (52%), Gaps = 3/128 (2%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCK---ALPSIT 207
LT+ SQP+ NA S GWG G +YQKA++E F +++ + ++ +
Sbjct: 496 LTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFS 555
Query: 206 YMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWAN 27
Y A + + +N + VTWGVFP + Q TI++ SF W+DEAF WS WA
Sbjct: 556 YYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAK 614
Query: 26 LYPEADPS 3
L+P P+
Sbjct: 615 LFPRNTPA 622
[184][TOP]
>UniRef100_B3LL40 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LL40_YEAS1
Length = 657
Score = 87.8 bits (216), Expect = 3e-16
Identities = 45/128 (35%), Positives = 67/128 (52%), Gaps = 3/128 (2%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCK---ALPSIT 207
LT+ SQP+ NA S GWG G +YQKA++E F +++ + ++ +
Sbjct: 496 LTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFS 555
Query: 206 YMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWAN 27
Y A + + +N + VTWGVFP + Q TI++ SF W+DEAF WS WA
Sbjct: 556 YYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAK 614
Query: 26 LYPEADPS 3
L+P P+
Sbjct: 615 LFPRNTPA 622
[185][TOP]
>UniRef100_P46151 Methylenetetrahydrofolate reductase 1 n=1 Tax=Saccharomyces
cerevisiae RepID=MTHR1_YEAST
Length = 657
Score = 87.8 bits (216), Expect = 3e-16
Identities = 45/128 (35%), Positives = 67/128 (52%), Gaps = 3/128 (2%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCK---ALPSIT 207
LT+ SQP+ NA S GWG G +YQKA++E F +++ + ++ +
Sbjct: 496 LTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFS 555
Query: 206 YMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWAN 27
Y A + + +N + VTWGVFP + Q TI++ SF W+DEAF WS WA
Sbjct: 556 YYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAK 614
Query: 26 LYPEADPS 3
L+P P+
Sbjct: 615 LFPRNTPA 622
[186][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 87.4 bits (215), Expect = 4e-16
Identities = 54/156 (34%), Positives = 73/156 (46%), Gaps = 32/156 (20%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKCKAL------P 216
T+ SQPSVN R+D P GWG G+V+QKA++EFFC + + K K L
Sbjct: 469 TLASQPSVNGVRNDHPIFGWGPRGEGFVFQKAFVEFFCPGDDFHS---KLKPLLNSYGHD 525
Query: 215 SITYMAVNKGEQWVSNTA-------------------------QADVNAVTWGVFPAKEI 111
+ A+N + S+T+ VNAVTWGVF KEI
Sbjct: 526 EFAWFAMNAKGDFQSSTSPEPPASPPTDSTEPLFDTDPLTDMDNGSVNAVTWGVFRGKEI 585
Query: 110 IQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPS 3
+ PTI++ SF W +EAF W W ++P S
Sbjct: 586 VTPTIIEAVSFRAWGEEAFGIW-EEWRRIFPRGSAS 620
[187][TOP]
>UniRef100_Q6BM19 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=Q6BM19_DEBHA
Length = 642
Score = 86.3 bits (212), Expect = 1e-15
Identities = 50/127 (39%), Positives = 68/127 (53%), Gaps = 9/127 (7%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKE----KLDAVVEKCKALPSIT 207
++ SQP+VN S GWG G +YQKA++E F K+ KL ++K +IT
Sbjct: 476 SLASQPAVNGCLSSDKIFGWGPGNGIIYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTIT 535
Query: 206 YMAVNKGEQWVSNTA-----QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWS 42
Y + + SN NA+TWGVFP+KE++QPTI+D SF W +EAF W
Sbjct: 536 YYCGDAEGRLTSNLNIDQEHYNSKNAITWGVFPSKEVLQPTIIDLESFKAWNEEAFILW- 594
Query: 41 RSWANLY 21
WA Y
Sbjct: 595 LEWARCY 601
[188][TOP]
>UniRef100_UPI00003BE162 hypothetical protein DEHA0F09867g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE162
Length = 642
Score = 85.5 bits (210), Expect = 2e-15
Identities = 50/127 (39%), Positives = 67/127 (52%), Gaps = 9/127 (7%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKE----KLDAVVEKCKALPSIT 207
++ SQP+VN S GWG G +YQKA++E F K+ KL ++K +IT
Sbjct: 476 SLASQPAVNGCLSSDKIFGWGPGNGIIYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTIT 535
Query: 206 YMAVNKGEQWVSNTA-----QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWS 42
Y + + SN NA+TWGVFP KE++QPTI+D SF W +EAF W
Sbjct: 536 YYCGDAEGRLTSNLNIDQEHYNSKNAITWGVFPLKEVLQPTIIDLESFKAWNEEAFILW- 594
Query: 41 RSWANLY 21
WA Y
Sbjct: 595 LEWARCY 601
[189][TOP]
>UniRef100_B8MDD4 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8MDD4_TALSN
Length = 713
Score = 85.1 bits (209), Expect = 2e-15
Identities = 53/150 (35%), Positives = 68/150 (45%), Gaps = 31/150 (20%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKC---KALPSIT 207
T+ SQP+VN RSD P GWG P G+V+QKA++EFFC V+ +
Sbjct: 513 TLASQPAVNGVRSDHPVFGWGPPGEGFVFQKAFVEFFCPSSDYQNKVKPTLLKHGSEEFS 572
Query: 206 YMAVN-----------------KGEQWVSNTAQADVN----------AVTWGVFPAKEII 108
+ A+N K E S A AD AVTWG F +EI
Sbjct: 573 WFAINAAGHLESSFLISTSSSPKPEDTSSAVAAADEEPLEIRESTGMAVTWGAFRGREIT 632
Query: 107 QPTIVDPASFNVWKDEAFETWSRSWANLYP 18
PTI++ SF W +EAF W W +YP
Sbjct: 633 TPTIIEEVSFRAWGEEAFRIWD-EWRRIYP 661
[190][TOP]
>UniRef100_A5DZ35 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DZ35_LODEL
Length = 622
Score = 84.3 bits (207), Expect = 4e-15
Identities = 46/123 (37%), Positives = 68/123 (55%), Gaps = 5/123 (4%)
Frame = -2
Query: 374 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAV 195
++ SQP+VN RS+ GWG G VYQK+++E F + + K + + TY
Sbjct: 464 SVASQPAVNGCRSNDNVFGWGPGNGVVYQKSFVELFIPAKDWKEL--KPRLDDATTYYVG 521
Query: 194 NKGEQ-----WVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWA 30
+K + + + + + NAVTWGVFP KE++QPT++D SF W +EAF W WA
Sbjct: 522 DKSGRIELSLFTNESTRHLKNAVTWGVFPLKEVVQPTVIDYESFKAWNEEAFLLW-LEWA 580
Query: 29 NLY 21
Y
Sbjct: 581 RCY 583
[191][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 82.8 bits (203), Expect = 1e-14
Identities = 52/129 (40%), Positives = 68/129 (52%), Gaps = 4/129 (3%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKAL-PSITYM 201
LTINSQP+VN + S P VGWG GYV+QKAYLEFF S E + A+++ K P + Y
Sbjct: 474 LTINSQPNVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEMVTALIKVLKRYEPRVNYH 533
Query: 200 AVN--KGEQWVSNTAQADVNAVTWGVFPAKEIIQPT-IVDPASFNVWKDEAFETWSRSWA 30
VN K Q + + +D G+ P + Q + ++ DEAF W WA
Sbjct: 534 IVNVHKHTQLLKLLSSSDT-----GMGPVIQNAQDLGNLSVIWISITDDEAFALWIEQWA 588
Query: 29 NLYPEADPS 3
LY E PS
Sbjct: 589 KLYEEESPS 597
[192][TOP]
>UniRef100_A7S359 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
RepID=A7S359_NEMVE
Length = 102
Score = 74.3 bits (181), Expect = 4e-12
Identities = 34/62 (54%), Positives = 43/62 (69%)
Frame = -2
Query: 377 LTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMA 198
L+INSQPSVNA S P +GWGG GY+YQKAYLEFF S E + ++++ K P + Y
Sbjct: 31 LSINSQPSVNAASSTDPLLGWGGEGGYIYQKAYLEFFASPEVVYILLQELKNYPQVNYHV 90
Query: 197 VN 192
VN
Sbjct: 91 VN 92