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[1][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 117 bits (294), Expect(2) = 7e-42
Identities = 58/58 (100%), Positives = 58/58 (100%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM 357
IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM
Sbjct: 241 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM 298
Score = 77.4 bits (189), Expect(2) = 7e-42
Identities = 37/39 (94%), Positives = 37/39 (94%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L NLGLIDESKISRSLPWRRPANVFRTKEDVRPIF ANR
Sbjct: 297 LMNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFWANR 335
[2][TOP]
>UniRef100_Q9SE60-2 Isoform 2 of Methylenetetrahydrofolate reductase 1 n=1
Tax=Arabidopsis thaliana RepID=Q9SE60-2
Length = 421
Score = 117 bits (294), Expect(2) = 7e-42
Identities = 58/58 (100%), Positives = 58/58 (100%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM 357
IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM
Sbjct: 241 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM 298
Score = 77.4 bits (189), Expect(2) = 7e-42
Identities = 37/39 (94%), Positives = 37/39 (94%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L NLGLIDESKISRSLPWRRPANVFRTKEDVRPIF ANR
Sbjct: 297 LMNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFWANR 335
[3][TOP]
>UniRef100_Q3EAG8 Methylenetetrahydrofolate reductase n=1 Tax=Arabidopsis thaliana
RepID=Q3EAG8_ARATH
Length = 407
Score = 117 bits (294), Expect(2) = 7e-42
Identities = 58/58 (100%), Positives = 58/58 (100%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM 357
IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM
Sbjct: 241 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM 298
Score = 77.4 bits (189), Expect(2) = 7e-42
Identities = 37/39 (94%), Positives = 37/39 (94%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L NLGLIDESKISRSLPWRRPANVFRTKEDVRPIF ANR
Sbjct: 297 LMNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFWANR 335
[4][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=B9DHL6_ARATH
Length = 402
Score = 117 bits (294), Expect(2) = 7e-42
Identities = 58/58 (100%), Positives = 58/58 (100%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM 357
IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM
Sbjct: 51 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM 108
Score = 77.4 bits (189), Expect(2) = 7e-42
Identities = 37/39 (94%), Positives = 37/39 (94%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L NLGLIDESKISRSLPWRRPANVFRTKEDVRPIF ANR
Sbjct: 107 LMNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFWANR 145
[5][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 97.8 bits (242), Expect(2) = 1e-35
Identities = 45/58 (77%), Positives = 52/58 (89%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM 357
IP E+ AALEPIKDN+EAVKAYGIH TEMCKK+LAHG+ SLHLYTLN++KSA+ ILM
Sbjct: 241 IPVEVMAALEPIKDNEEAVKAYGIHLGTEMCKKMLAHGVKSLHLYTLNMEKSALAILM 298
Score = 76.6 bits (187), Expect(2) = 1e-35
Identities = 36/39 (92%), Positives = 37/39 (94%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L NLG+IDESKISRSLPWRRPANVFRTKEDVRPIF ANR
Sbjct: 297 LMNLGMIDESKISRSLPWRRPANVFRTKEDVRPIFWANR 335
[6][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 100 bits (250), Expect(2) = 2e-34
Identities = 48/58 (82%), Positives = 54/58 (93%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM 357
IPAE+TAALEPIKDN+EAVKAYGIH TEMCKKILA GI +LHLYTLN++KSA+GILM
Sbjct: 241 IPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALGILM 298
Score = 69.7 bits (169), Expect(2) = 2e-34
Identities = 33/39 (84%), Positives = 34/39 (87%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L NLGLI+ESKISRSLPWR P NVFR KEDVRPIF ANR
Sbjct: 297 LMNLGLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANR 335
[7][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 100 bits (250), Expect(2) = 2e-34
Identities = 48/58 (82%), Positives = 54/58 (93%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM 357
IPAE+TAALEPIKDN+EAVKAYGIH TEMCKKILA GI +LHLYTLN++KSA+GILM
Sbjct: 241 IPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALGILM 298
Score = 69.7 bits (169), Expect(2) = 2e-34
Identities = 33/39 (84%), Positives = 34/39 (87%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L NLGLI+ESKISRSLPWR P NVFR KEDVRPIF ANR
Sbjct: 297 LMNLGLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANR 335
[8][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 101 bits (251), Expect(2) = 2e-34
Identities = 47/58 (81%), Positives = 54/58 (93%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM 357
IP+E+TAALEPIKDNDEAVKAYGIH TEMCKKILAHGI ++HLYTLN++KSA+ ILM
Sbjct: 241 IPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAHGIKTVHLYTLNMEKSALAILM 298
Score = 68.9 bits (167), Expect(2) = 2e-34
Identities = 32/39 (82%), Positives = 33/39 (84%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L NLGLI+ESKISR PWRRP NVFR KEDVRPIF ANR
Sbjct: 297 LMNLGLIEESKISRPFPWRRPTNVFRVKEDVRPIFWANR 335
[9][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 101 bits (251), Expect(2) = 2e-34
Identities = 47/58 (81%), Positives = 54/58 (93%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM 357
IP+E+TAALEPIKDNDEAVKAYGIH TEMCKKILAHGI ++HLYTLN++KSA+ ILM
Sbjct: 241 IPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAHGIKTVHLYTLNMEKSALAILM 298
Score = 68.9 bits (167), Expect(2) = 2e-34
Identities = 32/39 (82%), Positives = 33/39 (84%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L NLGLI+ESKISR PWRRP NVFR KEDVRPIF ANR
Sbjct: 297 LMNLGLIEESKISRPFPWRRPTNVFRVKEDVRPIFWANR 335
[10][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 100 bits (250), Expect(2) = 7e-34
Identities = 47/58 (81%), Positives = 54/58 (93%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM 357
IPAE+TAALEPIKDN+EAV+AYGIH TEMCKKILAHGI +LHLYTLN++KSA+ ILM
Sbjct: 255 IPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILM 312
Score = 67.4 bits (163), Expect(2) = 7e-34
Identities = 31/39 (79%), Positives = 34/39 (87%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L NLGLI+ESKI+R+LPWR P NVFR KEDVRPIF ANR
Sbjct: 311 LMNLGLIEESKITRALPWRPPTNVFRAKEDVRPIFWANR 349
[11][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 100 bits (250), Expect(2) = 1e-33
Identities = 47/58 (81%), Positives = 54/58 (93%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM 357
IPAE+TAALEPIKDN+EAV+AYGIH TEMCKKILAHGI +LHLYTLN++KSA+ ILM
Sbjct: 252 IPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILM 309
Score = 66.6 bits (161), Expect(2) = 1e-33
Identities = 31/39 (79%), Positives = 33/39 (84%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L NLGLI+ESKI+R LPWR P NVFR KEDVRPIF ANR
Sbjct: 308 LMNLGLIEESKITRPLPWRPPTNVFRVKEDVRPIFWANR 346
[12][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 100 bits (248), Expect(2) = 6e-33
Identities = 46/58 (79%), Positives = 54/58 (93%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM 357
IPAE+TAALEPIKDN+EAV+AYGIH TEMCKKI+AHGI +LHLYTLN++KSA+ ILM
Sbjct: 256 IPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKIMAHGIKTLHLYTLNMEKSALAILM 313
Score = 65.1 bits (157), Expect(2) = 6e-33
Identities = 31/39 (79%), Positives = 32/39 (82%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L NLGLI+ESKISR LPWR P NVFR KE VRPIF ANR
Sbjct: 312 LMNLGLIEESKISRPLPWRPPTNVFRVKEGVRPIFWANR 350
[13][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 96.7 bits (239), Expect(2) = 6e-33
Identities = 45/58 (77%), Positives = 53/58 (91%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM 357
IPAE+TAAL+PIKDN+EAVKAYGIH TEMCKKILA GI +LHLYTLN++K+A+ ILM
Sbjct: 229 IPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKTALAILM 286
Score = 68.6 bits (166), Expect(2) = 6e-33
Identities = 32/44 (72%), Positives = 36/44 (81%)
Frame = +2
Query: 437 TVVLKLQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
T + L NLGLI+ESK+SR+LPWR P NVFR KEDVRPIF ANR
Sbjct: 280 TALAILMNLGLIEESKLSRTLPWRPPTNVFRVKEDVRPIFWANR 323
[14][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 99.0 bits (245), Expect(2) = 2e-32
Identities = 47/58 (81%), Positives = 53/58 (91%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM 357
IP+E+TAAL+PIKDN+EAVK YGIH TEMCKKILA GI +LHLYTLN+DKSAIGILM
Sbjct: 241 IPSEITAALDPIKDNEEAVKQYGIHLGTEMCKKILATGIKTLHLYTLNMDKSAIGILM 298
Score = 64.3 bits (155), Expect(2) = 2e-32
Identities = 30/39 (76%), Positives = 32/39 (82%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L NLGLI+ESK+SR LPWR NVFR KEDVRPIF ANR
Sbjct: 297 LMNLGLIEESKVSRPLPWRPATNVFRVKEDVRPIFWANR 335
[15][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 97.8 bits (242), Expect(2) = 5e-32
Identities = 46/58 (79%), Positives = 53/58 (91%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM 357
IP+E+TAAL+PIKDN+EAV+ YGIH TEMCKKILA GI +LHLYTLN+DKSAIGILM
Sbjct: 241 IPSEITAALDPIKDNEEAVRQYGIHLGTEMCKKILATGIKTLHLYTLNMDKSAIGILM 298
Score = 64.3 bits (155), Expect(2) = 5e-32
Identities = 30/39 (76%), Positives = 32/39 (82%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L NLGLI+ESK+SR LPWR NVFR KEDVRPIF ANR
Sbjct: 297 LMNLGLIEESKVSRPLPWRPATNVFRVKEDVRPIFWANR 335
[16][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 100 bits (249), Expect(2) = 7e-31
Identities = 46/57 (80%), Positives = 54/57 (94%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGIL 354
IP+E+TAALEPIKDN+EAV+AYGIH TEMCKKILAHGI +LHLYTLN++KSA+GIL
Sbjct: 241 IPSEITAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALGIL 297
Score = 57.8 bits (138), Expect(2) = 7e-31
Identities = 28/39 (71%), Positives = 30/39 (76%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L NLGLID +KI R LPWR NV RTKE+VRPIF ANR
Sbjct: 297 LANLGLIDMTKIRRPLPWRPATNVLRTKENVRPIFWANR 335
[17][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 94.7 bits (234), Expect(2) = 1e-30
Identities = 43/57 (75%), Positives = 51/57 (89%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGIL 354
+PAE+ AALEPIKDNDEAV+AYGIH TEMCKKILAH I +LHLY+LN++KS +GIL
Sbjct: 241 VPAEIMAALEPIKDNDEAVRAYGIHLGTEMCKKILAHDIRTLHLYSLNLEKSVLGIL 297
Score = 62.8 bits (151), Expect(2) = 1e-30
Identities = 30/39 (76%), Positives = 32/39 (82%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
LQNLGLID S++SR LPWR P N RTKEDVRPIF ANR
Sbjct: 297 LQNLGLIDFSRVSRPLPWRPPTNSKRTKEDVRPIFWANR 335
[18][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 93.2 bits (230), Expect(2) = 3e-30
Identities = 42/57 (73%), Positives = 50/57 (87%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGIL 354
+PAE+ A LEPIKDNDEAV+AYGIH TEMCKKILAH I +LHLY+LN++KS +GIL
Sbjct: 241 VPAEIMATLEPIKDNDEAVRAYGIHLGTEMCKKILAHDIRTLHLYSLNLEKSVLGIL 297
Score = 62.8 bits (151), Expect(2) = 3e-30
Identities = 30/39 (76%), Positives = 32/39 (82%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
LQNLGLID SK++R LPWR P N RTKEDVRPIF ANR
Sbjct: 297 LQNLGLIDFSKVTRPLPWRPPTNSKRTKEDVRPIFWANR 335
[19][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 73.6 bits (179), Expect(2) = 2e-19
Identities = 34/58 (58%), Positives = 46/58 (79%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+PAE++ ALE IKDNDEAVKAYGI MC+++LA G + +H+YTLN++KSA+ IL
Sbjct: 235 VPAEISDALEAIKDNDEAVKAYGIDLGVRMCRQLLASGEVPGVHMYTLNLEKSAVAIL 292
Score = 46.6 bits (109), Expect(2) = 2e-19
Identities = 22/45 (48%), Positives = 29/45 (64%), Gaps = 1/45 (2%)
Frame = +2
Query: 437 TVVLKLQNLGLIDESKISRSLPWRR-PANVFRTKEDVRPIFGANR 568
+ V L+ LGL+D S++ R LPWR PA R E VRP+F +NR
Sbjct: 287 SAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSNR 331
[20][TOP]
>UniRef100_C6T731 Methylenetetrahydrofolate reductase n=1 Tax=Glycine max
RepID=C6T731_SOYBN
Length = 344
Score = 99.4 bits (246), Expect = 2e-19
Identities = 46/58 (79%), Positives = 53/58 (91%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILM 357
IPA++ AALEPIKDN+EAVKAYGIH TEMCKKILAHGI +LHLYTLN++KSA+ ILM
Sbjct: 242 IPADIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGINTLHLYTLNMEKSALAILM 299
[21][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 54.7 bits (130), Expect(2) = 1e-13
Identities = 24/58 (41%), Positives = 40/58 (68%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILA-HGITSLHLYTLNVDKSAIGIL 354
+P + +E IKDNDEA++ +GI AT +CKK+LA + +H+YTLN +++ + +L
Sbjct: 259 VPQRILDTIESIKDNDEAIRKFGIVEATNLCKKLLASDDVPGIHVYTLNREEAVVKLL 316
Score = 45.4 bits (106), Expect(2) = 1e-13
Identities = 24/43 (55%), Positives = 28/43 (65%)
Frame = +2
Query: 440 VVLKLQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
VV L+ +GL E I +SLPWR AN R EDVRPIF A+R
Sbjct: 312 VVKLLKRVGLWHEESIYKSLPWRPSANGKRISEDVRPIFWASR 354
[22][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 77.8 bits (190), Expect = 5e-13
Identities = 38/57 (66%), Positives = 47/57 (82%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGIL 354
IP+E+TAALEPIKDNDEAVKAYGIH TEMCKKILAHGI + L T+++ +G++
Sbjct: 241 IPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAHGIKTFGL-TMDLPWQNLGLI 296
Score = 72.4 bits (176), Expect = 2e-11
Identities = 35/45 (77%), Positives = 37/45 (82%)
Frame = +2
Query: 434 LTVVLKLQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
LT+ L QNLGLI+ESKISR PWRRP NVFR KEDVRPIF ANR
Sbjct: 284 LTMDLPWQNLGLIEESKISRPFPWRRPTNVFRVKEDVRPIFWANR 328
[23][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 64.3 bits (155), Expect(2) = 8e-13
Identities = 28/58 (48%), Positives = 41/58 (70%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITS-LHLYTLNVDKSAIGIL 354
+P E+TA +EPIKDND A++ YGI A MC+++L G+ S LH YTLN + + + +L
Sbjct: 273 VPQEITAVIEPIKDNDAAIRNYGIELAVTMCRELLVSGVVSGLHFYTLNREVATVEVL 330
Score = 33.1 bits (74), Expect(2) = 8e-13
Identities = 19/39 (48%), Positives = 24/39 (61%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ +E R LPW A+ R EDVRPIF A+R
Sbjct: 330 LKRLGIWNEDP-RRPLPWAVSAHPKRRVEDVRPIFWASR 367
[24][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 61.2 bits (147), Expect(2) = 8e-13
Identities = 27/57 (47%), Positives = 37/57 (64%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGIL 354
+P + LEPIKDNDE VK YG+ EM K++L G+ LH YTLN+++S +L
Sbjct: 234 VPQYIMDNLEPIKDNDEEVKKYGVRLCVEMSKRLLDFGVEGLHFYTLNLERSVRKVL 290
Score = 36.2 bits (82), Expect(2) = 8e-13
Identities = 18/39 (46%), Positives = 24/39 (61%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ L L+ ++S LPW + A R KE+VRPIF NR
Sbjct: 290 LKGLQLVTPDQLSPFLPWAQSAAGNRLKEEVRPIFWQNR 328
[25][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 57.4 bits (137), Expect(2) = 2e-12
Identities = 27/58 (46%), Positives = 39/58 (67%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
IP E+ A+EPI+DNDEA++ YG+H A M +++ G + LH YTLN + + I IL
Sbjct: 265 IPDEIREAIEPIRDNDEAIRNYGVHQAVTMIRELFDSGLVNGLHFYTLNREVATIQIL 322
Score = 38.5 bits (88), Expect(2) = 2e-12
Identities = 20/39 (51%), Positives = 26/39 (66%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ +GL E I R PW+R AN R +E+VRPIF A+R
Sbjct: 322 LKQIGLWTED-IQRPWPWKRTANYNRCEEEVRPIFWASR 359
[26][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 55.1 bits (131), Expect(2) = 3e-12
Identities = 26/57 (45%), Positives = 37/57 (64%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGIL 354
IP ALEP+K++D AVK G +EMC+K+L +GI LH YT+N+ +S +L
Sbjct: 232 IPKGWMEALEPVKNDDAAVKQIGRALVSEMCRKLLDNGINHLHFYTMNLAQSTTMVL 288
Score = 40.4 bits (93), Expect(2) = 3e-12
Identities = 19/49 (38%), Positives = 31/49 (63%)
Frame = +2
Query: 422 IPENLTVVLKLQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
+ ++ T+VL+ NL E+ + + LPWR+ + R +EDVRPIF +R
Sbjct: 280 LAQSTTMVLEELNLKPSTETPLQKPLPWRKSLGLGRREEDVRPIFWRHR 328
[27][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 61.2 bits (147), Expect(2) = 7e-12
Identities = 28/58 (48%), Positives = 40/58 (68%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P E+T+ LEPIKDND A++ YGI A EMC+ +L G + LH YTLN + + + +L
Sbjct: 280 VPEEITSILEPIKDNDAAIRNYGIQLAVEMCRVLLDSGKVPGLHFYTLNREVATMEVL 337
Score = 33.1 bits (74), Expect(2) = 7e-12
Identities = 20/39 (51%), Positives = 23/39 (58%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LGL E R LPW A+ R EDVRPIF A+R
Sbjct: 337 LRQLGLWTEDP-RRPLPWAVSAHPKRKVEDVRPIFWASR 374
[28][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 60.8 bits (146), Expect(2) = 1e-11
Identities = 28/58 (48%), Positives = 40/58 (68%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P E+ +EPIKDND A++ YGI A EMCK +LA G ++ LH YTLN + + + +L
Sbjct: 276 VPEEIKQVIEPIKDNDAAIRNYGIQQAVEMCKVLLASGEVSGLHFYTLNREVATMEVL 333
Score = 32.7 bits (73), Expect(2) = 1e-11
Identities = 20/39 (51%), Positives = 23/39 (58%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LGL E R LPW A+ R EDVRPIF A+R
Sbjct: 333 LRQLGLWAEDP-RRPLPWAISAHPKRKVEDVRPIFWASR 370
[29][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 56.2 bits (134), Expect(2) = 1e-11
Identities = 29/65 (44%), Positives = 39/65 (60%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMVF 363
IP + ALEP+K++D AV+ G +MCKKILA GI LH YT+N+ ++ IL
Sbjct: 232 IPPDWLEALEPVKNDDAAVRNLGKSLVADMCKKILASGIYHLHFYTMNLQQATKMILDEL 291
Query: 364 FSFPS 378
PS
Sbjct: 292 GLIPS 296
Score = 37.0 bits (84), Expect(2) = 1e-11
Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 2/41 (4%)
Frame = +2
Query: 452 LQNLGLIDESK--ISRSLPWRRPANVFRTKEDVRPIFGANR 568
L LGLI K + + LPWR+ + R +EDVRPIF +R
Sbjct: 288 LDELGLIPSHKTPLQKPLPWRQSLGLGRREEDVRPIFWRHR 328
[30][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 56.2 bits (134), Expect(2) = 1e-11
Identities = 29/65 (44%), Positives = 39/65 (60%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMVF 363
IP + ALEP+K++D AV+ G +MCKKILA GI LH YT+N+ ++ IL
Sbjct: 232 IPPDWLEALEPVKNDDAAVRNLGKSLVADMCKKILASGIYHLHFYTMNLQQATKMILDEL 291
Query: 364 FSFPS 378
PS
Sbjct: 292 GLIPS 296
Score = 37.0 bits (84), Expect(2) = 1e-11
Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 2/41 (4%)
Frame = +2
Query: 452 LQNLGLIDESK--ISRSLPWRRPANVFRTKEDVRPIFGANR 568
L LGLI K + + LPWR+ + R +EDVRPIF +R
Sbjct: 288 LDELGLIPSHKTPLQKPLPWRQSLGLGRREEDVRPIFWRHR 328
[31][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 59.7 bits (143), Expect(2) = 2e-11
Identities = 27/58 (46%), Positives = 39/58 (67%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P E+ +EPIKDND A++ YGI A MCK++LA G + LH YTLN + + + +L
Sbjct: 270 VPQEIKDVIEPIKDNDAAIRNYGIELAVTMCKELLASGLVPGLHFYTLNREVATMEVL 327
Score = 33.1 bits (74), Expect(2) = 2e-11
Identities = 19/39 (48%), Positives = 24/39 (61%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ +E R LPW A+ R EDVRPIF A+R
Sbjct: 327 LKRLGMWNEDP-RRPLPWAVSAHPKRRVEDVRPIFWASR 364
[32][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 53.5 bits (127), Expect(2) = 5e-11
Identities = 26/58 (44%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
IP AL+PIKD+D V+ G +EMC+K+L G I LH YT+N++K+ + IL
Sbjct: 232 IPQHFLDALDPIKDDDYLVREKGTELVSEMCQKLLESGYINHLHFYTMNLEKATVMIL 289
Score = 37.7 bits (86), Expect(2) = 5e-11
Identities = 22/52 (42%), Positives = 30/52 (57%), Gaps = 5/52 (9%)
Frame = +2
Query: 428 ENLTVVLKLQNLGLIDESKISR-----SLPWRRPANVFRTKEDVRPIFGANR 568
E TV++ L+ L LI+ K + LPWR+ N R+KE +RPIF NR
Sbjct: 282 EKATVMI-LEKLNLIEAVKSNEIVGVTELPWRKSLNPERSKESIRPIFWQNR 332
[33][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 57.0 bits (136), Expect(2) = 7e-11
Identities = 25/58 (43%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P E+ +EPIKDND A++ YGI A +C+++LA G + LH YTLN + + +L
Sbjct: 317 VPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEVL 374
Score = 33.9 bits (76), Expect(2) = 7e-11
Identities = 19/39 (48%), Positives = 24/39 (61%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ E R LPW A+ R +EDVRPIF A+R
Sbjct: 374 LKRLGMWTEDP-RRPLPWALSAHPKRREEDVRPIFWASR 411
[34][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 57.0 bits (136), Expect(2) = 7e-11
Identities = 25/58 (43%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P E+ +EPIKDND A++ YGI A +C+++LA G + LH YTLN + + +L
Sbjct: 299 VPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEVL 356
Score = 33.9 bits (76), Expect(2) = 7e-11
Identities = 19/39 (48%), Positives = 24/39 (61%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ E R LPW A+ R +EDVRPIF A+R
Sbjct: 356 LKRLGMWTEDP-RRPLPWALSAHPKRREEDVRPIFWASR 393
[35][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 57.0 bits (136), Expect(2) = 7e-11
Identities = 25/58 (43%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P E+ +EPIKDND A++ YGI A +C+++LA G + LH YTLN + + +L
Sbjct: 306 VPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEVL 363
Score = 33.9 bits (76), Expect(2) = 7e-11
Identities = 19/39 (48%), Positives = 24/39 (61%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ E R LPW A+ R +EDVRPIF A+R
Sbjct: 363 LKRLGMWTEDP-RRPLPWALSAHPKRREEDVRPIFWASR 400
[36][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 57.0 bits (136), Expect(2) = 7e-11
Identities = 25/58 (43%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P E+ +EPIKDND A++ YGI A +C+++LA G + LH YTLN + + +L
Sbjct: 276 VPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEVL 333
Score = 33.9 bits (76), Expect(2) = 7e-11
Identities = 19/39 (48%), Positives = 24/39 (61%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ E R LPW A+ R +EDVRPIF A+R
Sbjct: 333 LKRLGMWTEDP-RRPLPWALSAHPKRREEDVRPIFWASR 370
[37][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 58.9 bits (141), Expect(2) = 1e-10
Identities = 26/58 (44%), Positives = 40/58 (68%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P E+T+ +EPIKDND A++ YGI A +MC+ +L G + LH YTLN + + + +L
Sbjct: 280 LPEEITSIIEPIKDNDAAIRNYGIQLAVQMCRVLLDSGKVPGLHFYTLNREVATMEVL 337
Score = 31.2 bits (69), Expect(2) = 1e-10
Identities = 19/39 (48%), Positives = 23/39 (58%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LGL E R LPW A+ R EDVRPIF ++R
Sbjct: 337 LRQLGLWIEDP-RRPLPWAVSAHPKRKVEDVRPIFWSSR 374
[38][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 56.2 bits (134), Expect(2) = 1e-10
Identities = 25/58 (43%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P E+ +EPIKDND A++ YGI A +C ++LA G + LH YTLN + + +L
Sbjct: 317 VPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLHFYTLNREMATTEVL 374
Score = 33.9 bits (76), Expect(2) = 1e-10
Identities = 19/39 (48%), Positives = 24/39 (61%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ E R LPW A+ R +EDVRPIF A+R
Sbjct: 374 LKRLGMWTEDP-RRPLPWALSAHPKRREEDVRPIFWASR 411
[39][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 56.2 bits (134), Expect(2) = 1e-10
Identities = 25/58 (43%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P E+ +EPIKDND A++ YGI A +C ++LA G + LH YTLN + + +L
Sbjct: 299 VPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLHFYTLNREMATTEVL 356
Score = 33.9 bits (76), Expect(2) = 1e-10
Identities = 19/39 (48%), Positives = 24/39 (61%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ E R LPW A+ R +EDVRPIF A+R
Sbjct: 356 LKRLGMWTEDP-RRPLPWALSAHPKRREEDVRPIFWASR 393
[40][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 58.9 bits (141), Expect(2) = 1e-10
Identities = 26/58 (44%), Positives = 40/58 (68%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P E+T+ +EPIKDND A++ YGI A +MC+ +L G + LH YTLN + + + +L
Sbjct: 280 LPEEITSIIEPIKDNDAAIRNYGIQLAVQMCRVLLDSGKVPGLHFYTLNREVATMEVL 337
Score = 31.2 bits (69), Expect(2) = 1e-10
Identities = 19/39 (48%), Positives = 23/39 (58%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LGL E R LPW A+ R EDVRPIF ++R
Sbjct: 337 LRQLGLWIEDP-RRPLPWAVSAHPKRKVEDVRPIFWSSR 374
[41][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 56.2 bits (134), Expect(2) = 1e-10
Identities = 25/58 (43%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P E+ +EPIKDND A++ YGI A +C ++LA G + LH YTLN + + +L
Sbjct: 276 VPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLHFYTLNREMATTEVL 333
Score = 33.9 bits (76), Expect(2) = 1e-10
Identities = 19/39 (48%), Positives = 24/39 (61%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ E R LPW A+ R +EDVRPIF A+R
Sbjct: 333 LKRLGMWTEDP-RRPLPWALSAHPKRREEDVRPIFWASR 370
[42][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 57.8 bits (138), Expect(2) = 1e-10
Identities = 26/58 (44%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGIT-SLHLYTLNVDKSAIGIL 354
+P E+ +EPIKDND A++ YGI A MC+++L G+ LH YTLN + + I +L
Sbjct: 270 VPQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDSGLVHGLHFYTLNREVATIDVL 327
Score = 32.3 bits (72), Expect(2) = 1e-10
Identities = 18/39 (46%), Positives = 23/39 (58%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ E R +PW A+ R EDVRPIF A+R
Sbjct: 327 LKRLGMWKEDP-RRPMPWAMSAHPKRRVEDVRPIFWASR 364
[43][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 57.8 bits (138), Expect(2) = 1e-10
Identities = 26/58 (44%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGIT-SLHLYTLNVDKSAIGIL 354
+P E+ +EPIKDND A++ YGI A MC+++L G+ LH YTLN + + I +L
Sbjct: 270 VPQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDSGLVHGLHFYTLNREVATIDVL 327
Score = 32.3 bits (72), Expect(2) = 1e-10
Identities = 19/39 (48%), Positives = 23/39 (58%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ E R LPW A+ R EDVRPIF A+R
Sbjct: 327 LKRLGMWKEDP-RRPLPWAVSAHPKRRVEDVRPIFWASR 364
[44][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 57.8 bits (138), Expect(2) = 1e-10
Identities = 26/58 (44%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGIT-SLHLYTLNVDKSAIGIL 354
+P E+ +EPIKDND A++ YGI A MC+++L G+ LH YTLN + + I +L
Sbjct: 270 VPQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDSGLVHGLHFYTLNREVATIDVL 327
Score = 32.3 bits (72), Expect(2) = 1e-10
Identities = 19/39 (48%), Positives = 23/39 (58%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ E R LPW A+ R EDVRPIF A+R
Sbjct: 327 LKRLGMWKEDP-RRPLPWAVSAHPKRRVEDVRPIFWASR 364
[45][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 51.6 bits (122), Expect(2) = 1e-10
Identities = 23/58 (39%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
IP AL PIK++D A++ G +EMC+K++ G + LH YT+N+++S + IL
Sbjct: 235 IPQHFLDALNPIKEDDYAIREVGTQLVSEMCQKLIDSGYVNHLHFYTMNLERSTVMIL 292
Score = 38.5 bits (88), Expect(2) = 1e-10
Identities = 19/48 (39%), Positives = 28/48 (58%), Gaps = 4/48 (8%)
Frame = +2
Query: 437 TVVLKLQNLGLIDESK----ISRSLPWRRPANVFRTKEDVRPIFGANR 568
+ V+ L+ L L++ K + LPWR+ N R+KE +RPIF NR
Sbjct: 287 STVMILEKLNLVESIKDNDAVVEILPWRKSLNPSRSKESIRPIFWQNR 334
[46][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 52.4 bits (124), Expect(2) = 1e-10
Identities = 27/65 (41%), Positives = 37/65 (56%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMVF 363
IP ALEP+K++D AV+ G MCKK+LA GI LH YT+N+ ++ +L
Sbjct: 232 IPPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLASGIHHLHFYTMNLQQATKMVLDEL 291
Query: 364 FSFPS 378
PS
Sbjct: 292 GLIPS 296
Score = 37.4 bits (85), Expect(2) = 1e-10
Identities = 19/41 (46%), Positives = 26/41 (63%), Gaps = 2/41 (4%)
Frame = +2
Query: 452 LQNLGLID--ESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L LGLI E+ + + LPWR+ + R +EDVRPIF +R
Sbjct: 288 LDELGLIPSHETPLQKPLPWRQSLGLGRREEDVRPIFWRHR 328
[47][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 52.4 bits (124), Expect(2) = 1e-10
Identities = 27/65 (41%), Positives = 37/65 (56%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMVF 363
IP ALEP+K++D AV+ G MCKK+LA GI LH YT+N+ ++ +L
Sbjct: 232 IPPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLASGIHHLHFYTMNLQQATKMVLDEL 291
Query: 364 FSFPS 378
PS
Sbjct: 292 GLIPS 296
Score = 37.4 bits (85), Expect(2) = 1e-10
Identities = 19/41 (46%), Positives = 26/41 (63%), Gaps = 2/41 (4%)
Frame = +2
Query: 452 LQNLGLID--ESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L LGLI E+ + + LPWR+ + R +EDVRPIF +R
Sbjct: 288 LDELGLIPSHETPLQKPLPWRQSLGLGRREEDVRPIFWRHR 328
[48][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 52.4 bits (124), Expect(2) = 1e-10
Identities = 27/65 (41%), Positives = 37/65 (56%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMVF 363
IP ALEP+K++D AV+ G MCKK+LA GI LH YT+N+ ++ +L
Sbjct: 232 IPPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLASGIHHLHFYTMNLQQATKMVLDEL 291
Query: 364 FSFPS 378
PS
Sbjct: 292 GLIPS 296
Score = 37.4 bits (85), Expect(2) = 1e-10
Identities = 19/41 (46%), Positives = 26/41 (63%), Gaps = 2/41 (4%)
Frame = +2
Query: 452 LQNLGLID--ESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L LGLI E+ + + LPWR+ + R +EDVRPIF +R
Sbjct: 288 LDELGLIPSHETPLQKPLPWRQSLGLGRREEDVRPIFWRHR 328
[49][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 53.9 bits (128), Expect(2) = 1e-10
Identities = 28/65 (43%), Positives = 37/65 (56%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMVF 363
+P ALEP K++D AVK G +EMC+KIL GI LH YT+N+ +S +L
Sbjct: 232 VPPSWMEALEPCKNDDAAVKQIGKKLVSEMCRKILDSGIRHLHFYTMNLAQSTKMVLEEL 291
Query: 364 FSFPS 378
PS
Sbjct: 292 DLIPS 296
Score = 35.8 bits (81), Expect(2) = 1e-10
Identities = 18/41 (43%), Positives = 26/41 (63%), Gaps = 2/41 (4%)
Frame = +2
Query: 452 LQNLGLI--DESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ L LI E+ + + LPWR+ + R +EDVRPIF +R
Sbjct: 288 LEELDLIPSSETPLQKPLPWRQSLGLGRREEDVRPIFWRHR 328
[50][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 52.4 bits (124), Expect(2) = 1e-10
Identities = 25/58 (43%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
IP ALEPIK++D V+A G +EMC K++ G + LH YT+N++++ I IL
Sbjct: 232 IPQHFLDALEPIKEDDYLVRAKGTELVSEMCTKLIKSGYVNHLHFYTMNLERATIMIL 289
Score = 37.4 bits (85), Expect(2) = 1e-10
Identities = 21/52 (40%), Positives = 30/52 (57%), Gaps = 5/52 (9%)
Frame = +2
Query: 428 ENLTVVLKLQNLGLIDESKISR-----SLPWRRPANVFRTKEDVRPIFGANR 568
E T+++ L+NL LI+ K LPWR+ + R+KE +RPIF NR
Sbjct: 282 ERATIMI-LENLNLIESVKSHEVIGGSDLPWRKSLHPQRSKESIRPIFWQNR 332
[51][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 52.4 bits (124), Expect(2) = 1e-10
Identities = 25/58 (43%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
IP ALEPIK++D V+A G +EMC K++ G + LH YT+N++++ I IL
Sbjct: 232 IPQHFLDALEPIKEDDYLVRAKGTELVSEMCTKLIKSGYVNHLHFYTMNLERATIMIL 289
Score = 37.4 bits (85), Expect(2) = 1e-10
Identities = 21/52 (40%), Positives = 30/52 (57%), Gaps = 5/52 (9%)
Frame = +2
Query: 428 ENLTVVLKLQNLGLIDESKISR-----SLPWRRPANVFRTKEDVRPIFGANR 568
E T+++ L+NL LI+ K LPWR+ + R+KE +RPIF NR
Sbjct: 282 ERATIMI-LENLNLIESVKSHEVIGGSDLPWRKSLHPQRSKESIRPIFWQNR 332
[52][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 60.1 bits (144), Expect(2) = 1e-10
Identities = 27/58 (46%), Positives = 42/58 (72%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P E LEP+KD+D+AV+ G +MC+KILA G +T LHLYT+N++++++ IL
Sbjct: 235 LPPEFLERLEPVKDDDQAVREIGTVLVADMCRKILASGHVTHLHLYTMNLERASLMIL 292
Score = 29.6 bits (65), Expect(2) = 1e-10
Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 8/47 (17%)
Frame = +2
Query: 452 LQNLGLIDES--------KISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ L LID + +L WR+ N R KE VRPIF R
Sbjct: 292 LERLQLIDTGGAGVRRRPSTNETLTWRKSLNPTRRKEGVRPIFWQRR 338
[53][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 56.2 bits (134), Expect(2) = 3e-10
Identities = 25/58 (43%), Positives = 39/58 (67%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P ++ +EPIKDND A++ YGI A +C+++LA G + LH YTLN + + I +L
Sbjct: 275 VPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNREVATIEVL 332
Score = 32.7 bits (73), Expect(2) = 3e-10
Identities = 20/39 (51%), Positives = 23/39 (58%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LGL E R LPW A+ R EDVRPIF A+R
Sbjct: 332 LKRLGLWIEDP-RRPLPWALSAHPKRRVEDVRPIFWASR 369
[54][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 56.2 bits (134), Expect(2) = 3e-10
Identities = 25/58 (43%), Positives = 39/58 (67%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P ++ +EPIKDND A++ YGI A +C+++LA G + LH YTLN + + I +L
Sbjct: 275 VPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNREVATIEVL 332
Score = 32.7 bits (73), Expect(2) = 3e-10
Identities = 20/39 (51%), Positives = 23/39 (58%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LGL E R LPW A+ R EDVRPIF A+R
Sbjct: 332 LKRLGLWIEDP-RRPLPWALSAHPKRRVEDVRPIFWASR 369
[55][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 55.1 bits (131), Expect(2) = 3e-10
Identities = 24/58 (41%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P E+ +EPIKDND A++ YG+ A MC+++L G + LH YTLN + + +L
Sbjct: 278 VPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEVL 335
Score = 33.9 bits (76), Expect(2) = 3e-10
Identities = 20/39 (51%), Positives = 24/39 (61%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LGL +E R LPW A+ R EDVRPIF A+R
Sbjct: 335 LKRLGLWNEDP-RRPLPWAVSAHPKRRVEDVRPIFWASR 372
[56][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 48.9 bits (115), Expect(2) = 3e-10
Identities = 21/58 (36%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKIL-AHGITSLHLYTLNVDKSAIGIL 354
+P + LEPIK++DEA++ YG+ A MC+++L + + +H+YTLN + + +L
Sbjct: 253 VPQYIIDDLEPIKNDDEAIREYGVKLAVSMCRELLSSDDVPGIHVYTLNREVATTELL 310
Score = 40.0 bits (92), Expect(2) = 3e-10
Identities = 20/39 (51%), Positives = 26/39 (66%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
LQ LGL + R LPW+ AN+ R +EDVRPIF ++R
Sbjct: 310 LQQLGLWRPYQSHRLLPWKPSANLKRLQEDVRPIFWSSR 348
[57][TOP]
>UniRef100_UPI0000ECA34F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Gallus
gallus RepID=UPI0000ECA34F
Length = 640
Score = 55.5 bits (132), Expect(2) = 3e-10
Identities = 24/58 (41%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGIT-SLHLYTLNVDKSAIGIL 354
+P E+ +EPIKDND A++ YG+ A MC+++L G+ LH YTLN + + +L
Sbjct: 266 VPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGLVHGLHFYTLNREVATTEVL 323
Score = 33.1 bits (74), Expect(2) = 3e-10
Identities = 19/39 (48%), Positives = 24/39 (61%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ +E R LPW A+ R EDVRPIF A+R
Sbjct: 323 LKRLGIWNEDP-RRPLPWAVSAHPKRRVEDVRPIFWASR 360
[58][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
RepID=UPI0000E814FF
Length = 508
Score = 55.5 bits (132), Expect(2) = 3e-10
Identities = 24/58 (41%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGIT-SLHLYTLNVDKSAIGIL 354
+P E+ +EPIKDND A++ YG+ A MC+++L G+ LH YTLN + + +L
Sbjct: 134 VPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGLVHGLHFYTLNREVATTEVL 191
Score = 33.1 bits (74), Expect(2) = 3e-10
Identities = 19/39 (48%), Positives = 24/39 (61%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ +E R LPW A+ R EDVRPIF A+R
Sbjct: 191 LKRLGIWNEDP-RRPLPWAVSAHPKRRVEDVRPIFWASR 228
[59][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 53.9 bits (128), Expect(2) = 5e-10
Identities = 23/58 (39%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P ++ +EPIKDND A++ YGI A +C+++L G + LH YTLN + + + +L
Sbjct: 316 VPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEVL 373
Score = 33.9 bits (76), Expect(2) = 5e-10
Identities = 19/39 (48%), Positives = 24/39 (61%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ E R LPW A+ R +EDVRPIF A+R
Sbjct: 373 LKQLGMWTEDP-RRPLPWALSAHPKRREEDVRPIFWASR 410
[60][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 53.9 bits (128), Expect(2) = 5e-10
Identities = 23/58 (39%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P ++ +EPIKDND A++ YGI A +C+++L G + LH YTLN + + + +L
Sbjct: 316 VPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEVL 373
Score = 33.9 bits (76), Expect(2) = 5e-10
Identities = 19/39 (48%), Positives = 24/39 (61%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ E R LPW A+ R +EDVRPIF A+R
Sbjct: 373 LKQLGMWTEDP-RRPLPWALSAHPKRREEDVRPIFWASR 410
[61][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 53.9 bits (128), Expect(2) = 5e-10
Identities = 23/58 (39%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P ++ +EPIKDND A++ YGI A +C+++L G + LH YTLN + + + +L
Sbjct: 316 VPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEVL 373
Score = 33.9 bits (76), Expect(2) = 5e-10
Identities = 19/39 (48%), Positives = 24/39 (61%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ E R LPW A+ R +EDVRPIF A+R
Sbjct: 373 LKQLGMWTEDP-RRPLPWALSAHPKRREEDVRPIFWASR 410
[62][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 53.9 bits (128), Expect(2) = 5e-10
Identities = 23/58 (39%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P ++ +EPIKDND A++ YGI A +C+++L G + LH YTLN + + + +L
Sbjct: 275 VPQKIKDVIEPIKDNDAAIRNYGIELAVRLCRELLDSGLVPGLHFYTLNREVATMEVL 332
Score = 33.9 bits (76), Expect(2) = 5e-10
Identities = 19/39 (48%), Positives = 24/39 (61%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ E R LPW A+ R +EDVRPIF A+R
Sbjct: 332 LKQLGMWTEDP-RRPLPWALSAHPKRREEDVRPIFWASR 369
[63][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 52.8 bits (125), Expect(2) = 5e-10
Identities = 25/57 (43%), Positives = 37/57 (64%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGIL 354
IP ALEP+K++D AV+ G EMC+K+LA+GI LH YT+N+ ++ +L
Sbjct: 232 IPQAWLDALEPVKNDDVAVRDIGKSLVAEMCRKLLANGIHHLHFYTMNLAQATRMVL 288
Score = 35.0 bits (79), Expect(2) = 5e-10
Identities = 17/43 (39%), Positives = 25/43 (58%)
Frame = +2
Query: 440 VVLKLQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
+VL+ N E + +LPW++ + R +EDVRPIF NR
Sbjct: 286 MVLEELNWAPSAERPLQHALPWKQSKGLGRREEDVRPIFWRNR 328
[64][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
RepID=A8PV87_BRUMA
Length = 656
Score = 53.9 bits (128), Expect(2) = 7e-10
Identities = 27/65 (41%), Positives = 44/65 (67%), Gaps = 1/65 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGILMV 360
IP + +LEPIK++D+AV+ +GI A +C+ +L++G TS+HL+TLN + S+ IL
Sbjct: 287 IPDSILTSLEPIKNDDDAVRNFGIWHAVTLCRTLLSNGSATSIHLFTLNREASSREILQQ 346
Query: 361 FFSFP 375
+P
Sbjct: 347 LGLWP 351
Score = 33.5 bits (75), Expect(2) = 7e-10
Identities = 21/41 (51%), Positives = 26/41 (63%), Gaps = 2/41 (4%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRR--PANVFRTKEDVRPIFGANR 568
LQ LGL S + R+LPWR ++ R KEDVRPIF + R
Sbjct: 344 LQQLGLWPRSPM-RALPWRLFGESHPVRCKEDVRPIFWSMR 383
[65][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 54.7 bits (130), Expect(2) = 7e-10
Identities = 25/58 (43%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P E+ +EPIKDND A++ YGI A +C+++LA G + LH YTLN + + +L
Sbjct: 275 VPQEIKDVIEPIKDNDGAIRNYGIDQAVSLCQQLLASGLVPGLHFYTLNREVATTEVL 332
Score = 32.7 bits (73), Expect(2) = 7e-10
Identities = 19/39 (48%), Positives = 23/39 (58%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ E R LPW A+ R +EDVRPIF A R
Sbjct: 332 LKRLGMWVEDP-RRPLPWALSAHPKRREEDVRPIFWATR 369
[66][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 57.0 bits (136), Expect(2) = 7e-10
Identities = 24/58 (41%), Positives = 40/58 (68%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P A L+P+KD+D+AV+ G +MC+K+L G +T LH+YT+N++K+ I +L
Sbjct: 235 VPEAFMAKLDPVKDDDQAVREVGTELVAQMCQKLLDSGYVTHLHMYTMNLEKACIMVL 292
Score = 30.4 bits (67), Expect(2) = 7e-10
Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 5/47 (10%)
Frame = +2
Query: 443 VLKLQNLGLIDESK-ISRS----LPWRRPANVFRTKEDVRPIFGANR 568
++ L LGL+ E + I R +PWR+ + R E VRPIF R
Sbjct: 289 IMVLDRLGLLSEDEDIFRDEVVPMPWRKSLHPQRRNESVRPIFWQKR 335
[67][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 53.1 bits (126), Expect(2) = 1e-09
Identities = 23/58 (39%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P + +EPIKDND A++ YGI A +C+++L G + LH YTLN + + + +L
Sbjct: 316 VPQTIKDVIEPIKDNDAAIRNYGIELAVNLCRELLDSGLVPGLHFYTLNREVATMEVL 373
Score = 33.5 bits (75), Expect(2) = 1e-09
Identities = 19/39 (48%), Positives = 24/39 (61%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ E R LPW A+ R +EDVRPIF A+R
Sbjct: 373 LKQLGMWTEDP-RRPLPWAVSAHPKRREEDVRPIFWASR 410
[68][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 53.1 bits (126), Expect(2) = 1e-09
Identities = 23/58 (39%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P + +EPIKDND A++ YGI A +C+++L G + LH YTLN + + + +L
Sbjct: 281 VPQTIKDVIEPIKDNDAAIRNYGIELAVNLCRELLDSGLVPGLHFYTLNREVATMEVL 338
Score = 33.5 bits (75), Expect(2) = 1e-09
Identities = 19/39 (48%), Positives = 24/39 (61%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ E R LPW A+ R +EDVRPIF A+R
Sbjct: 338 LKQLGMWTEDP-RRPLPWAVSAHPKRREEDVRPIFWASR 375
[69][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 53.5 bits (127), Expect(2) = 1e-09
Identities = 27/65 (41%), Positives = 38/65 (58%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMVF 363
IP + ALEP+K++D AV+ G MC+KILA GI LH YT+N+ ++ +L
Sbjct: 232 IPPDWLEALEPVKNDDAAVRNLGKSLVANMCRKILAAGIYHLHFYTMNLQQATKMVLGEL 291
Query: 364 FSFPS 378
PS
Sbjct: 292 ELIPS 296
Score = 33.1 bits (74), Expect(2) = 1e-09
Identities = 18/41 (43%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Frame = +2
Query: 452 LQNLGLIDESK--ISRSLPWRRPANVFRTKEDVRPIFGANR 568
L L LI K + + LPWR+ + R +EDVRPIF +R
Sbjct: 288 LGELELIPSHKTPLQKPLPWRQSLGLGRREEDVRPIFWRHR 328
[70][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 50.4 bits (119), Expect(2) = 1e-09
Identities = 23/53 (43%), Positives = 33/53 (62%), Gaps = 2/53 (3%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAH--GITSLHLYTLNVDK 336
+P ALEPIK++DE V+ G +MC++IL GI LH YT+N++K
Sbjct: 233 VPQSFLDALEPIKNDDEKVREVGTRLVADMCRRILKEDIGIRGLHFYTMNLEK 285
Score = 36.2 bits (82), Expect(2) = 1e-09
Identities = 16/39 (41%), Positives = 23/39 (58%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ L L+ + + LPWR+ R +E +RPIF ANR
Sbjct: 291 LEELNLVPRIETIKPLPWRQSLTPNRRQESIRPIFWANR 329
[71][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6H337_AJECH
Length = 524
Score = 53.5 bits (127), Expect(2) = 1e-09
Identities = 27/65 (41%), Positives = 38/65 (58%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMVF 363
IP + ALEP+K++D AV+ G MC+KILA GI LH YT+N+ ++ +L
Sbjct: 123 IPPDWLEALEPVKNDDAAVRNLGKSLVANMCRKILAAGIYHLHFYTMNLQQATKMVLGEL 182
Query: 364 FSFPS 378
PS
Sbjct: 183 ELIPS 187
Score = 33.1 bits (74), Expect(2) = 1e-09
Identities = 18/41 (43%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Frame = +2
Query: 452 LQNLGLIDESK--ISRSLPWRRPANVFRTKEDVRPIFGANR 568
L L LI K + + LPWR+ + R +EDVRPIF +R
Sbjct: 179 LGELELIPSHKTPLQKPLPWRQSLGLGRREEDVRPIFWRHR 219
[72][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Canis lupus familiaris RepID=UPI00005A03BF
Length = 780
Score = 53.1 bits (126), Expect(2) = 2e-09
Identities = 23/58 (39%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P ++ +EPIKDND A++ YGI A +C+++L G + LH YTLN + + +L
Sbjct: 401 VPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHFYTLNREMATTEVL 458
Score = 32.7 bits (73), Expect(2) = 2e-09
Identities = 19/39 (48%), Positives = 24/39 (61%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ E R LPW A+ R +EDVRPIF A+R
Sbjct: 458 LKRLGMWIEDP-RRPLPWAVSAHPKRREEDVRPIFWASR 495
[73][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 53.1 bits (126), Expect(2) = 2e-09
Identities = 23/58 (39%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P ++ +EPIKDND A++ YGI A +C+++L G + LH YTLN + + +L
Sbjct: 317 VPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHFYTLNREMATTEVL 374
Score = 32.7 bits (73), Expect(2) = 2e-09
Identities = 19/39 (48%), Positives = 24/39 (61%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG+ E R LPW A+ R +EDVRPIF A+R
Sbjct: 374 LKRLGMWIEDP-RRPLPWAVSAHPKRREEDVRPIFWASR 411
[74][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 53.1 bits (126), Expect(2) = 2e-09
Identities = 24/57 (42%), Positives = 37/57 (64%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGIL 354
IP T ALEP+K++D V+ G +MC+K++A GIT LH YT+N+ ++ +L
Sbjct: 232 IPQHWTDALEPVKNDDVEVREVGKMLVADMCRKLIAAGITHLHFYTMNLAQATRMVL 288
Score = 32.7 bits (73), Expect(2) = 2e-09
Identities = 17/41 (41%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Frame = +2
Query: 452 LQNLGLID--ESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ L L+ E+ + + LPWR + R E+VRPIF NR
Sbjct: 288 LEELDLLPDVEAPLEKPLPWRPSLGLNRRDENVRPIFWRNR 328
[75][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 51.6 bits (122), Expect(2) = 2e-09
Identities = 26/65 (40%), Positives = 36/65 (55%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMVF 363
+P ALEP+K++D AVK G MC+KIL GI LH YT+N+ ++ +L
Sbjct: 232 VPESWMEALEPVKNDDAAVKQIGKKLVANMCQKILDSGIRHLHFYTMNLAQATKMVLEEL 291
Query: 364 FSFPS 378
PS
Sbjct: 292 KLIPS 296
Score = 34.3 bits (77), Expect(2) = 2e-09
Identities = 18/41 (43%), Positives = 25/41 (60%), Gaps = 2/41 (4%)
Frame = +2
Query: 452 LQNLGLID--ESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ L LI E+ + + LPWR+ + R EDVRPIF +R
Sbjct: 288 LEELKLIPSYETPLQKPLPWRQSLGLGRRDEDVRPIFWRHR 328
[76][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 51.6 bits (122), Expect(2) = 2e-09
Identities = 26/65 (40%), Positives = 36/65 (55%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMVF 363
+P ALEP+K++D AVK G MC+KIL GI LH YT+N+ ++ +L
Sbjct: 232 VPESWMEALEPVKNDDAAVKQIGKKLVANMCQKILDSGIRHLHFYTMNLAQATKMVLEEL 291
Query: 364 FSFPS 378
PS
Sbjct: 292 KLIPS 296
Score = 34.3 bits (77), Expect(2) = 2e-09
Identities = 18/41 (43%), Positives = 25/41 (60%), Gaps = 2/41 (4%)
Frame = +2
Query: 452 LQNLGLID--ESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ L LI E+ + + LPWR+ + R EDVRPIF +R
Sbjct: 288 LEELKLIPSYETPLQKPLPWRQSLGLGRRDEDVRPIFWRHR 328
[77][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 51.6 bits (122), Expect(2) = 2e-09
Identities = 27/65 (41%), Positives = 38/65 (58%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMVF 363
IP E LEP+K++D AV+ G E+C+KILA GI LH YT+N+ ++ +L
Sbjct: 232 IPDEWMQRLEPVKNDDVAVRDIGKTLVAELCRKILAAGIHHLHFYTMNLAQATRMVLEEL 291
Query: 364 FSFPS 378
PS
Sbjct: 292 DWMPS 296
Score = 34.3 bits (77), Expect(2) = 2e-09
Identities = 14/28 (50%), Positives = 19/28 (67%)
Frame = +2
Query: 485 ISRSLPWRRPANVFRTKEDVRPIFGANR 568
+ ++LPW+R + R EDVRPIF NR
Sbjct: 301 VKQALPWKRSLGLGRQVEDVRPIFWRNR 328
[78][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 52.4 bits (124), Expect(2) = 3e-09
Identities = 25/58 (43%), Positives = 36/58 (62%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
IP AL+PIKD+D V+ G +EMC K+L G + LH YT+N++K+ + IL
Sbjct: 232 IPQHFLDALDPIKDDDFLVRERGTELVSEMCNKLLQSGYVNHLHFYTMNLEKATVMIL 289
Score = 33.1 bits (74), Expect(2) = 3e-09
Identities = 20/52 (38%), Positives = 29/52 (55%), Gaps = 5/52 (9%)
Frame = +2
Query: 428 ENLTVVLKLQNLGLIDESKI-----SRSLPWRRPANVFRTKEDVRPIFGANR 568
E TV++ L+ L LI+ K LPWR+ + R+KE +RPIF +R
Sbjct: 282 EKATVMI-LEKLNLIEAIKSHDVVGGSELPWRKSLHPERSKESIRPIFWQHR 332
[79][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 52.4 bits (124), Expect(2) = 3e-09
Identities = 25/58 (43%), Positives = 36/58 (62%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
IP AL+PIKD+D V+ G +EMC K+L G + LH YT+N++K+ + IL
Sbjct: 232 IPQHFLDALDPIKDDDFLVRERGTELVSEMCNKLLQSGYVNHLHFYTMNLEKATVMIL 289
Score = 33.1 bits (74), Expect(2) = 3e-09
Identities = 20/52 (38%), Positives = 29/52 (55%), Gaps = 5/52 (9%)
Frame = +2
Query: 428 ENLTVVLKLQNLGLIDESKI-----SRSLPWRRPANVFRTKEDVRPIFGANR 568
E TV++ L+ L LI+ K LPWR+ + R+KE +RPIF +R
Sbjct: 282 EKATVMI-LEKLNLIEAIKSHDVVGGSELPWRKSLHPERSKESIRPIFWQHR 332
[80][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 52.4 bits (124), Expect(2) = 3e-09
Identities = 27/65 (41%), Positives = 38/65 (58%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMVF 363
IP E A LEP+K++D AV+ G EMC+KI+ GI LH YT+N+ ++ +L
Sbjct: 232 IPEEWMAKLEPVKNDDVAVREIGKTLVAEMCRKIVDAGIRHLHFYTMNLAQATRMVLEEL 291
Query: 364 FSFPS 378
PS
Sbjct: 292 DWLPS 296
Score = 33.1 bits (74), Expect(2) = 3e-09
Identities = 14/28 (50%), Positives = 18/28 (64%)
Frame = +2
Query: 485 ISRSLPWRRPANVFRTKEDVRPIFGANR 568
+ R+LPW++ R EDVRPIF NR
Sbjct: 301 LKRALPWKQSLGSGRRDEDVRPIFWRNR 328
[81][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 48.5 bits (114), Expect(2) = 3e-09
Identities = 21/57 (36%), Positives = 37/57 (64%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGIL 354
IP + +A+LE +K++D AV+ G EMC++I+ G+ LH YT+N+ ++ +L
Sbjct: 232 IPPKWSASLEAVKNDDSAVRNIGKDLVAEMCRRIIQAGVHHLHFYTMNLAQATRMVL 288
Score = 37.0 bits (84), Expect(2) = 3e-09
Identities = 18/43 (41%), Positives = 26/43 (60%)
Frame = +2
Query: 440 VVLKLQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
+VL+ NL + + +LPWR+ + R +EDVRPIF NR
Sbjct: 286 MVLEELNLTPSTQRPLKHALPWRQSLGLGRREEDVRPIFWKNR 328
[82][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 52.0 bits (123), Expect(2) = 3e-09
Identities = 26/65 (40%), Positives = 38/65 (58%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMVF 363
IP + ALEP+K++D AV+ G MC+K+LA GI LH YT+N+ ++ +L
Sbjct: 218 IPPDWLEALEPVKNDDVAVRNLGKSLVANMCRKMLAAGIHHLHFYTMNLQQATKMVLGEL 277
Query: 364 FSFPS 378
PS
Sbjct: 278 ELIPS 282
Score = 33.1 bits (74), Expect(2) = 3e-09
Identities = 18/41 (43%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Frame = +2
Query: 452 LQNLGLIDESK--ISRSLPWRRPANVFRTKEDVRPIFGANR 568
L L LI K + + LPWR+ + R +EDVRPIF +R
Sbjct: 274 LGELELIPSHKTPLQKPLPWRQSLGLGRREEDVRPIFWRHR 314
[83][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 50.4 bits (119), Expect(2) = 4e-09
Identities = 24/58 (41%), Positives = 35/58 (60%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
IP LEPIKD+D V+ G ++MC K+L G + LH YT+N++++ I IL
Sbjct: 232 IPPHFLEVLEPIKDDDYLVREKGTELVSQMCTKLLQSGFVNHLHFYTMNLERATIMIL 289
Score = 34.3 bits (77), Expect(2) = 4e-09
Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 5/52 (9%)
Frame = +2
Query: 428 ENLTVVLKLQNLGLIDESKISRS-----LPWRRPANVFRTKEDVRPIFGANR 568
E T+++ L+ L +I+ K + LPWR+ + R+KE +RPIF NR
Sbjct: 282 ERATIMI-LETLNIIEPVKAHENTGGDELPWRKSLHPQRSKETIRPIFWQNR 332
[84][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S5W8_NEMVE
Length = 619
Score = 53.5 bits (127), Expect(2) = 1e-08
Identities = 24/58 (41%), Positives = 41/58 (70%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P E+ L+ K++ EA++A+GI AT+MC+++ A G + +HLYTLN++K + IL
Sbjct: 252 VPNEILEVLKSGKEDLEAIQAFGIQHATKMCQELFASGKVQGIHLYTLNIEKPVMSIL 309
Score = 30.0 bits (66), Expect(2) = 1e-08
Identities = 17/39 (43%), Positives = 27/39 (69%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+NL + E ++++ LPW+ + R+ EDVRPIF A+R
Sbjct: 309 LENLKISKEPELNK-LPWQ--LSDVRSGEDVRPIFWASR 344
[85][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TTE9_VANPO
Length = 612
Score = 48.9 bits (115), Expect(2) = 1e-08
Identities = 21/58 (36%), Positives = 35/58 (60%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITS-LHLYTLNVDKSAIGIL 354
+P L P+ D+DE V+ G +MC+++L G+ S LHLYT+N+++ + IL
Sbjct: 225 VPDNFLQRLAPVSDDDELVREIGTQLVVDMCRRLLESGVVSHLHLYTMNLERPPLVIL 282
Score = 34.7 bits (78), Expect(2) = 1e-08
Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 11/50 (22%)
Frame = +2
Query: 452 LQNLGLIDESKISRSL-----------PWRRPANVFRTKEDVRPIFGANR 568
L+ LGL+ E+ +S+ PWRR N R E+VRPIF +R
Sbjct: 282 LERLGLLPEASAEQSIDTFTNEPPAVVPWRRSLNPQRRNEEVRPIFWKSR 331
[86][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 48.9 bits (115), Expect(2) = 1e-08
Identities = 24/53 (45%), Positives = 32/53 (60%), Gaps = 2/53 (3%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKIL--AHGITSLHLYTLNVDK 336
IP ALEP+K +DE V+ G +MC+KIL GI LH YT+N++K
Sbjct: 193 IPQFFLDALEPVKSDDEKVREVGTKLVADMCRKILDSGLGIRGLHFYTMNLEK 245
Score = 34.7 bits (78), Expect(2) = 1e-08
Identities = 16/39 (41%), Positives = 22/39 (56%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ L L+ + + LPWR+ R E +RPIF ANR
Sbjct: 251 LEELNLVPRIETIKPLPWRQCLTPNRRNETIRPIFWANR 289
[87][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 50.4 bits (119), Expect(2) = 1e-08
Identities = 23/57 (40%), Positives = 36/57 (63%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGIL 354
IP T ALEPIK++D V+ G +MC++++ GIT LH YT+N+ ++ +L
Sbjct: 232 IPQHWTDALEPIKNDDVEVREVGKGLVADMCRRLIEAGITHLHFYTMNLAQATRMVL 288
Score = 32.7 bits (73), Expect(2) = 1e-08
Identities = 17/41 (41%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Frame = +2
Query: 452 LQNLGLIDE--SKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ L L+ + S + + LPWR + R E+VRPIF NR
Sbjct: 288 LEELDLLPDPGSPLEKPLPWRPSLGLNRRDENVRPIFWRNR 328
[88][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 63.2 bits (152), Expect = 1e-08
Identities = 29/58 (50%), Positives = 41/58 (70%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
IP E+ +EPIKDND A++ YGI AT+MC+ +L G + LH+YTLN++ + I IL
Sbjct: 248 IPEEIQKVIEPIKDNDAAIRKYGIDLATDMCRTLLNSGKVHGLHMYTLNLETATIQIL 305
[89][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 50.4 bits (119), Expect(2) = 3e-08
Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
IP + LEP+KD+D V+ G +MC+K+L G I LH YT+N++K+ + +L
Sbjct: 233 IPQDFLDQLEPVKDDDMRVRELGTQLVADMCQKMLDSGKIKHLHFYTMNLEKATVMVL 290
Score = 31.6 bits (70), Expect(2) = 3e-08
Identities = 17/42 (40%), Positives = 21/42 (50%)
Frame = +2
Query: 443 VLKLQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
V+ L+ L L + LPWR + R E VRPIF NR
Sbjct: 287 VMVLERLNLPAQDSAVAPLPWRPSLALGRQDETVRPIFWKNR 328
[90][TOP]
>UniRef100_B9XQY3 Methylenetetrahydrofolate reductase n=1 Tax=bacterium Ellin514
RepID=B9XQY3_9BACT
Length = 303
Score = 62.0 bits (149), Expect = 3e-08
Identities = 28/57 (49%), Positives = 37/57 (64%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGIL 354
+P+ L + LE + DNDEA AYGI +ATE C ++L G LH+YTLN S I +L
Sbjct: 240 LPSRLVSCLEKLADNDEAAAAYGIDYATEQCAELLREGAPGLHMYTLNKAPSTIQVL 296
[91][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 62.0 bits (149), Expect = 3e-08
Identities = 32/61 (52%), Positives = 41/61 (67%), Gaps = 3/61 (4%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSL---HLYTLNVDKSAIGIL 354
+P E+ LEPIKD+DEAVK G A EMC++ILA I + H YTLN+++SA IL
Sbjct: 258 VPDEIWKRLEPIKDDDEAVKEIGCSLAAEMCRQILADPIAKIDGVHFYTLNLERSATRIL 317
Query: 355 M 357
M
Sbjct: 318 M 318
[92][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 49.7 bits (117), Expect(2) = 4e-08
Identities = 25/65 (38%), Positives = 38/65 (58%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMVF 363
+P E A LE +K++D AV+ G +MC+KIL+ GI LH YT+N+ ++ +L
Sbjct: 232 VPEEWMAKLESVKNDDVAVRDIGKTLVADMCRKILSAGIRHLHFYTMNLAQATRMVLEEL 291
Query: 364 FSFPS 378
PS
Sbjct: 292 DWLPS 296
Score = 32.0 bits (71), Expect(2) = 4e-08
Identities = 13/28 (46%), Positives = 18/28 (64%)
Frame = +2
Query: 485 ISRSLPWRRPANVFRTKEDVRPIFGANR 568
+ ++LPW++ R EDVRPIF NR
Sbjct: 301 LKQALPWKQSLGFGRRDEDVRPIFWRNR 328
[93][TOP]
>UniRef100_A8Q9P3 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8Q9P3_MALGO
Length = 515
Score = 47.4 bits (111), Expect(2) = 5e-08
Identities = 23/61 (37%), Positives = 37/61 (60%), Gaps = 3/61 (4%)
Frame = +1
Query: 205 ALEPIKDNDEAVKAYGIHFATEMCKKILAH---GITSLHLYTLNVDKSAIGILMVFFSFP 375
AL+P+K++DE V+ G +MCKKIL H I +H+YT+N+++ + +L P
Sbjct: 164 ALDPVKEDDEQVRIVGTRLVGDMCKKILEHPDLDIHGVHIYTMNLERGSRMLLEYLGLTP 223
Query: 376 S 378
S
Sbjct: 224 S 224
Score = 33.9 bits (76), Expect(2) = 5e-08
Identities = 17/39 (43%), Positives = 22/39 (56%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LGL + LPWR R +E++RPIF ANR
Sbjct: 216 LEYLGLTPSVQQLHPLPWRPSLTPKRREENIRPIFWANR 254
[94][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 49.3 bits (116), Expect(2) = 6e-08
Identities = 23/56 (41%), Positives = 34/56 (60%), Gaps = 3/56 (5%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAH---GITSLHLYTLNVDKSA 342
+P+ AL P++ +DE V+ G +MCK IL + GI LH+YTLN++K A
Sbjct: 236 VPSHFYEALNPVRGDDEKVRQVGTKLVADMCKTILDNKEAGIKGLHIYTLNLEKGA 291
Score = 31.6 bits (70), Expect(2) = 6e-08
Identities = 16/39 (41%), Positives = 20/39 (51%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L+ LG + LPWR R +E +RPIF ANR
Sbjct: 295 LRELGFEGRREQIAPLPWRPSLTPSRREETIRPIFWANR 333
[95][TOP]
>UniRef100_B7GB47 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B7GB47_PHATR
Length = 376
Score = 60.5 bits (145), Expect = 9e-08
Identities = 28/58 (48%), Positives = 40/58 (68%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P L A +E IKD+ AVKA+G+ F EMC+ +LA G ++ LH YTLN++K G+L
Sbjct: 315 VPETLRARMEAIKDDAAAVKAFGVEFGVEMCRTLLASGHVSVLHFYTLNLEKVVYGVL 372
[96][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 50.4 bits (119), Expect(2) = 1e-07
Identities = 22/55 (40%), Positives = 36/55 (65%), Gaps = 2/55 (3%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAH--GITSLHLYTLNVDKSA 342
+P AL+P++D+D+ V+ G EMCKKI+ GI+ LH+YT+N++K +
Sbjct: 249 VPQYFHDALDPVRDDDQKVREIGTRLVGEMCKKIVGTGLGISGLHIYTMNLEKGS 303
Score = 29.3 bits (64), Expect(2) = 1e-07
Identities = 16/39 (41%), Positives = 18/39 (46%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
L LGL LPW R +E +RPIF ANR
Sbjct: 307 LDYLGLTPSVNQVSPLPWTPSLTPKRREEKIRPIFWANR 345
[97][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 44.3 bits (103), Expect(2) = 2e-07
Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 6/63 (9%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGIT------SLHLYTLNVDKSAI 345
+P + LE +K +D+ VK G+ MC +I+++G+ LH YTLN++ S
Sbjct: 206 VPRAIADQLEQVKGDDQRVKDLGVEICVAMCSQIMSYGVDHTHSSGGLHFYTLNLESSVC 265
Query: 346 GIL 354
I+
Sbjct: 266 RII 268
Score = 34.7 bits (78), Expect(2) = 2e-07
Identities = 16/39 (41%), Positives = 23/39 (58%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
++ L ++D +R LPWR R +E+VRPIF NR
Sbjct: 268 IERLMMVDNHVATRVLPWRPSKASSRQEENVRPIFWRNR 306
[98][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 44.3 bits (103), Expect(2) = 2e-07
Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 6/63 (9%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGIT------SLHLYTLNVDKSAI 345
+P + LE +K +D+ VK G+ MC +I+++G+ LH YTLN++ S
Sbjct: 206 VPRAIADQLEQVKGDDQRVKDLGVEICVAMCSQIMSYGVDHTHSSGGLHFYTLNLESSVC 265
Query: 346 GIL 354
I+
Sbjct: 266 RII 268
Score = 34.7 bits (78), Expect(2) = 2e-07
Identities = 16/39 (41%), Positives = 23/39 (58%)
Frame = +2
Query: 452 LQNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
++ L ++D +R LPWR R +E+VRPIF NR
Sbjct: 268 IERLMMVDNHVATRVLPWRPSKASSRQEENVRPIFWRNR 306
[99][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 58.9 bits (141), Expect = 3e-07
Identities = 24/52 (46%), Positives = 35/52 (67%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKS 339
IP L P+KD+DE V+ G+ EMC+K++A GIT LH YT+N++K+
Sbjct: 232 IPQHFMDTLVPVKDDDEGVRERGVELIVEMCRKLIASGITRLHFYTMNLEKA 283
[100][TOP]
>UniRef100_A7QB31 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7QB31_VITVI
Length = 93
Score = 58.5 bits (140), Expect = 3e-07
Identities = 25/36 (69%), Positives = 31/36 (86%)
Frame = +1
Query: 193 ELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGI 300
++TAALEPIKDN++AV YGIH TEMCKK+L +GI
Sbjct: 19 KVTAALEPIKDNEKAVNTYGIHLGTEMCKKVLGNGI 54
[101][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 44.3 bits (103), Expect(2) = 4e-07
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P+ L+ KD+D V+ G +MC K++ G + LH YT+N++KS I +L
Sbjct: 218 VPSWFQKQLDASKDDDSEVRCLGTQLVADMCLKLVESGYVNHLHFYTMNLEKSTIMVL 275
Score = 33.9 bits (76), Expect(2) = 4e-07
Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 14/58 (24%)
Frame = +2
Query: 437 TVVLKLQNLGLID--------------ESKISRSLPWRRPANVFRTKEDVRPIFGANR 568
+ ++ L+ L LID ES+++ +PWRR N R E +RPIF +NR
Sbjct: 270 STIMVLEKLQLIDTHNQPVASVRDCGVESQVT--VPWRRSLNPTRVNESIRPIFWSNR 325
[102][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 58.2 bits (139), Expect = 4e-07
Identities = 28/66 (42%), Positives = 40/66 (60%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMVF 363
IP E ALEP+K++D AVK G EMC+K+LA G+ LH YT+N+ ++ +L
Sbjct: 232 IPPEWLEALEPVKNDDAAVKEIGKRLIAEMCRKLLAAGLNHLHFYTMNLAQATQSVLDEL 291
Query: 364 FSFPSK 381
PS+
Sbjct: 292 KLIPSE 297
[103][TOP]
>UniRef100_B4D0K5 Methylenetetrahydrofolate reductase n=1 Tax=Chthoniobacter flavus
Ellin428 RepID=B4D0K5_9BACT
Length = 297
Score = 57.0 bits (136), Expect = 1e-06
Identities = 25/57 (43%), Positives = 36/57 (63%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGIL 354
+PA+ L+ + +DEAV AYGI +ATE C +L G+ LH YTLN +S + I+
Sbjct: 233 LPAQFLRRLDELDGDDEAVAAYGIEYATEQCASLLEFGVPGLHFYTLNKARSTVQIV 289
[104][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 56.6 bits (135), Expect = 1e-06
Identities = 29/70 (41%), Positives = 42/70 (60%), Gaps = 1/70 (1%)
Frame = +1
Query: 187 PAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAH-GITSLHLYTLNVDKSAIGILMVF 363
P ++ LEPIK +D VK +GIH + +M K I GI + HLYTLN++KSA ++ V
Sbjct: 260 PEDVLEQLEPIKMDDAKVKEHGIHLSIDMIKSIREQTGIRAFHLYTLNLEKSATCVIKVL 319
Query: 364 FSFPSKLVSV 393
P + S+
Sbjct: 320 ADVPDQSASI 329
[105][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 56.2 bits (134), Expect = 2e-06
Identities = 26/66 (39%), Positives = 40/66 (60%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMVF 363
IP + ALEP+K++D AVK G +MC+++LA GI LH YT+N+ ++ +L
Sbjct: 232 IPPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAAGINHLHFYTMNLAQATQAVLEEL 291
Query: 364 FSFPSK 381
PS+
Sbjct: 292 KLIPSE 297
[106][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 56.2 bits (134), Expect = 2e-06
Identities = 26/66 (39%), Positives = 40/66 (60%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMVF 363
IP + ALEP+K++D AVK G +MC+++LA GI LH YT+N+ ++ +L
Sbjct: 232 IPPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAAGINHLHFYTMNLAQATQAVLEEL 291
Query: 364 FSFPSK 381
PS+
Sbjct: 292 KLIPSE 297
[107][TOP]
>UniRef100_Q0EWI5 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0EWI5_9PROT
Length = 251
Score = 55.8 bits (133), Expect = 2e-06
Identities = 26/56 (46%), Positives = 37/56 (66%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGI 351
IPA L ++PI+D+ EAVKA GI A + C+++L G+ LH YTLN ++ I I
Sbjct: 188 IPAWLHEQMQPIRDDLEAVKALGIELAAKQCRELLQAGVPGLHFYTLNKSEATIAI 243
[108][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 55.8 bits (133), Expect = 2e-06
Identities = 24/52 (46%), Positives = 35/52 (67%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKS 339
IP ALEP+KD+D V+ G EMC+K++ +GIT LH YT+N++K+
Sbjct: 233 IPQHFIDALEPLKDDDALVREKGSELMAEMCQKLVDNGITRLHFYTMNLEKA 284
[109][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 55.8 bits (133), Expect = 2e-06
Identities = 26/66 (39%), Positives = 40/66 (60%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMVF 363
IP + ALEP+K++D AVK G +MC+++LA GI LH YT+N+ ++ +L
Sbjct: 232 IPPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAAGIKHLHFYTMNLAQATQAVLEEL 291
Query: 364 FSFPSK 381
PS+
Sbjct: 292 KLIPSE 297
[110][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 55.5 bits (132), Expect = 3e-06
Identities = 25/58 (43%), Positives = 41/58 (70%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
IP ++ L+PIKD+DE V+ G + EMC+K+L G ++ LH+YT+N++K+ + IL
Sbjct: 237 IPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMIL 294
[111][TOP]
>UniRef100_B5VIK4 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VIK4_YEAS6
Length = 411
Score = 55.5 bits (132), Expect = 3e-06
Identities = 25/58 (43%), Positives = 41/58 (70%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
IP ++ L+PIKD+DE V+ G + EMC+K+L G ++ LH+YT+N++K+ + IL
Sbjct: 48 IPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMIL 105
[112][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 55.5 bits (132), Expect = 3e-06
Identities = 25/58 (43%), Positives = 41/58 (70%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
IP ++ L+PIKD+DE V+ G + EMC+K+L G ++ LH+YT+N++K+ + IL
Sbjct: 237 IPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMIL 294
[113][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 55.5 bits (132), Expect = 3e-06
Identities = 25/58 (43%), Positives = 41/58 (70%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
IP ++ L+PIKD+DE V+ G + EMC+K+L G ++ LH+YT+N++K+ + IL
Sbjct: 237 IPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMIL 294
[114][TOP]
>UniRef100_UPI000194E904 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH), partial n=1 Tax=Taeniopygia guttata
RepID=UPI000194E904
Length = 345
Score = 55.1 bits (131), Expect = 4e-06
Identities = 24/58 (41%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG-ITSLHLYTLNVDKSAIGIL 354
+P E+ +EPIKDND A++ YG+ A MC+++L G + LH YTLN + + +L
Sbjct: 278 VPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEVL 335
[115][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 55.1 bits (131), Expect = 4e-06
Identities = 28/66 (42%), Positives = 40/66 (60%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMVF 363
IP E ALEP+K++D AVK G +MC+++LA GI LH YT+N+ +S +L
Sbjct: 232 IPPEWLEALEPVKNDDAAVKEIGKGLIADMCRRLLAAGINHLHFYTMNLAQSTQLVLEEL 291
Query: 364 FSFPSK 381
PS+
Sbjct: 292 NLTPSE 297
[116][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 54.7 bits (130), Expect = 5e-06
Identities = 28/57 (49%), Positives = 35/57 (61%)
Frame = +1
Query: 184 IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGIL 354
IP E LEPIK +D AV+ G E+C+KILA GI LH YT+N+ +S IL
Sbjct: 227 IPEEWLQRLEPIKTDDAAVRIVGRQLVVELCRKILAAGIHHLHFYTMNLAQSTALIL 283