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[1][TOP]
>UniRef100_B9DI07 AT1G74040 protein (Fragment) n=1 Tax=Arabidopsis thaliana
RepID=B9DI07_ARATH
Length = 491
Score = 360 bits (923), Expect = 5e-98
Identities = 184/184 (100%), Positives = 184/184 (100%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV
Sbjct: 286 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 345
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY
Sbjct: 346 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 405
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA
Sbjct: 406 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 465
Query: 543 LNKM 554
LNKM
Sbjct: 466 LNKM 469
[2][TOP]
>UniRef100_Q9C550 2-isopropylmalate synthase 2, chloroplastic n=1 Tax=Arabidopsis
thaliana RepID=LEU12_ARATH
Length = 631
Score = 360 bits (923), Expect = 5e-98
Identities = 184/184 (100%), Positives = 184/184 (100%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV
Sbjct: 426 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 485
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY
Sbjct: 486 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 545
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA
Sbjct: 546 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 605
Query: 543 LNKM 554
LNKM
Sbjct: 606 LNKM 609
[3][TOP]
>UniRef100_Q5FAL5 Putative 2-isopropylmalate synthase n=1 Tax=Brassica oleracea
RepID=Q5FAL5_BRAOL
Length = 623
Score = 335 bits (858), Expect = 2e-90
Identities = 166/184 (90%), Positives = 181/184 (98%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHALKDRL ELGYVLDD QLS++FWRFK+VAE+KKRVTDAD+IALVSDEVFQPEA+
Sbjct: 420 KLSGRHALKDRLTELGYVLDDEQLSSIFWRFKSVAERKKRVTDADIIALVSDEVFQPEAL 479
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
WKLLD+QITCGTLGLST+TVKLAD+DGKEHVACS+GTGPVD+AYKAVDLIVKEPATLLEY
Sbjct: 480 WKLLDIQITCGTLGLSTATVKLADADGKEHVACSMGTGPVDSAYKAVDLIVKEPATLLEY 539
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
SMNAVTEGIDAIATTRVLIRG+NNYS+TNA+TGE V+RTFSGTGAGMDIVVSSVKAYVGA
Sbjct: 540 SMNAVTEGIDAIATTRVLIRGNNNYSTTNAITGEEVQRTFSGTGAGMDIVVSSVKAYVGA 599
Query: 543 LNKM 554
LNKM
Sbjct: 600 LNKM 603
[4][TOP]
>UniRef100_Q30DX9 2-isopropylmalate synthase 1 n=1 Tax=Brassica insularis
RepID=Q30DX9_9BRAS
Length = 623
Score = 335 bits (858), Expect = 2e-90
Identities = 166/184 (90%), Positives = 181/184 (98%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHALKDRL ELGYVLDD QLS++FWRFK+VAE+KKRVTDAD+IALVSDEVFQPEA+
Sbjct: 420 KLSGRHALKDRLTELGYVLDDEQLSSIFWRFKSVAERKKRVTDADIIALVSDEVFQPEAL 479
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
WKLLD+QITCGTLGLST+TVKLAD+DGKEHVACS+GTGPVD+AYKAVDLIVKEPATLLEY
Sbjct: 480 WKLLDIQITCGTLGLSTATVKLADADGKEHVACSMGTGPVDSAYKAVDLIVKEPATLLEY 539
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
SMNAVTEGIDAIATTRVLIRG+NNYS+TNA+TGE V+RTFSGTGAGMDIVVSSVKAYVGA
Sbjct: 540 SMNAVTEGIDAIATTRVLIRGNNNYSTTNAITGEEVQRTFSGTGAGMDIVVSSVKAYVGA 599
Query: 543 LNKM 554
LNKM
Sbjct: 600 LNKM 603
[5][TOP]
>UniRef100_UPI000034F3A5 MAML-4 (METHYLTHIOALKYLMALATE SYNTHASE-LIKE 4); 2-isopropylmalate
synthase n=1 Tax=Arabidopsis thaliana
RepID=UPI000034F3A5
Length = 631
Score = 333 bits (855), Expect = 4e-90
Identities = 167/184 (90%), Positives = 176/184 (95%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHALKDRL ELGY LDD QLS +FWRFK VAEQKKRVTDAD+IALVSDEVFQPEAV
Sbjct: 428 KLSGRHALKDRLTELGYQLDDEQLSTIFWRFKTVAEQKKRVTDADIIALVSDEVFQPEAV 487
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
WKLLD+QITCGTLGLST+TVKLAD+DGKEHVACS+GTGPVD+AYKAVDLIVKEPATLLEY
Sbjct: 488 WKLLDIQITCGTLGLSTATVKLADADGKEHVACSIGTGPVDSAYKAVDLIVKEPATLLEY 547
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
SMNAVTEGIDAIATTRVLIRG N YSSTNA+TGE V+RTFSGTGAGMDIVVSSVKAYVGA
Sbjct: 548 SMNAVTEGIDAIATTRVLIRGSNKYSSTNAITGEEVQRTFSGTGAGMDIVVSSVKAYVGA 607
Query: 543 LNKM 554
LNKM
Sbjct: 608 LNKM 611
[6][TOP]
>UniRef100_B2D157 2-isopropylmalate synthase n=1 Tax=Brassica oleracea
RepID=B2D157_BRAOL
Length = 672
Score = 329 bits (844), Expect = 7e-89
Identities = 164/184 (89%), Positives = 177/184 (96%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHALKDRL ELGYVLDD QLS +FWRFK+VAEQKKRVTDAD+IALVSDEVFQPEAV
Sbjct: 469 KLSGRHALKDRLTELGYVLDDEQLSTIFWRFKSVAEQKKRVTDADIIALVSDEVFQPEAV 528
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
WK+LD+QITCGTLGLST+TVKLAD+DGKEH ACS+GTGPVD+AYKAVDLIVKEPATLLEY
Sbjct: 529 WKVLDIQITCGTLGLSTATVKLADADGKEHCACSMGTGPVDSAYKAVDLIVKEPATLLEY 588
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
SMNAVTEGIDAIATTRVL+RG+N Y+STNA+TGE V RTFSGTGAGMDIVVSSVKAYVGA
Sbjct: 589 SMNAVTEGIDAIATTRVLVRGNNTYTSTNAITGEEVLRTFSGTGAGMDIVVSSVKAYVGA 648
Query: 543 LNKM 554
LNKM
Sbjct: 649 LNKM 652
[7][TOP]
>UniRef100_Q9LPR4 2-isopropylmalate synthase 1, chloroplastic n=1 Tax=Arabidopsis
thaliana RepID=LEU11_ARATH
Length = 675
Score = 308 bits (789), Expect = 2e-82
Identities = 167/228 (73%), Positives = 176/228 (77%), Gaps = 44/228 (19%)
Frame = +3
Query: 3 KLSGRHALKDRLNE-----------------------------LGYVLDDGQLSNLFWRF 95
KLSGRHALKDRL E LGY LDD QLS +FWRF
Sbjct: 428 KLSGRHALKDRLTEVHSNLTHTNTCIAIFVGDTNVLLSFVHFQLGYQLDDEQLSTIFWRF 487
Query: 96 KAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLGLSTSTVKLADSDGKEHV 275
K VAEQKKRVTDAD+IALVSDEVFQPEAVWKLLD+QITCGTLGLST+TVKLAD+DGKEHV
Sbjct: 488 KTVAEQKKRVTDADIIALVSDEVFQPEAVWKLLDIQITCGTLGLSTATVKLADADGKEHV 547
Query: 276 ACSVGTGPVDAAYKAVDLIVK---------------EPATLLEYSMNAVTEGIDAIATTR 410
ACS+GTGPVD+AYKAVDLIVK EPATLLEYSMNAVTEGIDAIATTR
Sbjct: 548 ACSIGTGPVDSAYKAVDLIVKVLFIPLRLSSTNNSPEPATLLEYSMNAVTEGIDAIATTR 607
Query: 411 VLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGALNKM 554
VLIRG N YSSTNA+TGE V+RTFSGTGAGMDIVVSSVKAYVGALNKM
Sbjct: 608 VLIRGSNKYSSTNAITGEEVQRTFSGTGAGMDIVVSSVKAYVGALNKM 655
[8][TOP]
>UniRef100_B9H597 Predicted protein (Fragment) n=1 Tax=Populus trichocarpa
RepID=B9H597_POPTR
Length = 558
Score = 304 bits (779), Expect = 3e-81
Identities = 152/184 (82%), Positives = 169/184 (91%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHALKDRLNELGY LDD QL N+FWRFKAVAE KKRVTDADLIALVSDEVFQPE V
Sbjct: 354 KLSGRHALKDRLNELGYELDDAQLGNIFWRFKAVAETKKRVTDADLIALVSDEVFQPENV 413
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
WKL D+Q+TCGTLGLST+TVKL +DG+EHVACS+GTGPVD+AYKAV+LIVKEP TLLEY
Sbjct: 414 WKLHDLQVTCGTLGLSTATVKLLSADGEEHVACSLGTGPVDSAYKAVNLIVKEPVTLLEY 473
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
SM AVTEGIDAIATTRV+IRG+N ++ T+A+T E +RTFSG+GAGMDIVVSSVKAYVGA
Sbjct: 474 SMIAVTEGIDAIATTRVVIRGENQHAPTHALTDEPFQRTFSGSGAGMDIVVSSVKAYVGA 533
Query: 543 LNKM 554
LNKM
Sbjct: 534 LNKM 537
[9][TOP]
>UniRef100_B9SX30 Isopropylmalate synthase, putative n=1 Tax=Ricinus communis
RepID=B9SX30_RICCO
Length = 632
Score = 302 bits (774), Expect = 1e-80
Identities = 151/184 (82%), Positives = 169/184 (91%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHALKDRL ELGY L+D QL +FWRFKAVAE KKRVTDADLIALVSDEVFQPE V
Sbjct: 427 KLSGRHALKDRLKELGYELNDEQLGTIFWRFKAVAETKKRVTDADLIALVSDEVFQPEIV 486
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
WKL D+Q+TCGTLGLST+TVKL ++DG+EH+ACSVG+GPVDA YKAVDLIVKEP LLEY
Sbjct: 487 WKLGDLQVTCGTLGLSTATVKLINADGEEHIACSVGSGPVDAGYKAVDLIVKEPVELLEY 546
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
SMNAVTEGIDAIATTRVLIR ++N++ST+A+TGE +RTFSG+GAGMDIVVSSVKAYVGA
Sbjct: 547 SMNAVTEGIDAIATTRVLIRREDNHTSTHALTGEPFQRTFSGSGAGMDIVVSSVKAYVGA 606
Query: 543 LNKM 554
LNKM
Sbjct: 607 LNKM 610
[10][TOP]
>UniRef100_B7FLQ1 Putative uncharacterized protein n=1 Tax=Medicago truncatula
RepID=B7FLQ1_MEDTR
Length = 416
Score = 293 bits (751), Expect = 4e-78
Identities = 145/184 (78%), Positives = 165/184 (89%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHA++ RL ELGY L D Q+ +LFWRFKAVAEQKKR+TDADL ALVSDEVFQ E +
Sbjct: 229 KLSGRHAMRKRLEELGYELKDDQVESLFWRFKAVAEQKKRITDADLRALVSDEVFQAEPI 288
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
WKL D+Q+TCGTLGLST+TVKL DG H+ACSVGTGPVD+AYKAVDLIVKEPATLLEY
Sbjct: 289 WKLDDLQVTCGTLGLSTATVKLVGDDGSAHIACSVGTGPVDSAYKAVDLIVKEPATLLEY 348
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
SM AVTEGIDAIATTRV+IRGD + +ST+A+TGESV+RTFSGTGAGMD+VVSSVKAY+ A
Sbjct: 349 SMIAVTEGIDAIATTRVVIRGDTDQTSTHALTGESVQRTFSGTGAGMDVVVSSVKAYIAA 408
Query: 543 LNKM 554
+NKM
Sbjct: 409 INKM 412
[11][TOP]
>UniRef100_B5LAV3 Putative isopropylmalate synthase n=1 Tax=Capsicum annuum
RepID=B5LAV3_CAPAN
Length = 602
Score = 283 bits (725), Expect = 5e-75
Identities = 136/184 (73%), Positives = 169/184 (91%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHAL+ ++ ELGY ++ +L +LFWRFK+VAE+KK++TD DLIAL+SDEVFQP+ V
Sbjct: 400 KLSGRHALQAKMLELGYEIEGKELDDLFWRFKSVAEKKKKITDDDLIALMSDEVFQPQFV 459
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
W+L ++Q+TCG+LGLST+TVKL D+DGKEH++CSVGTGPVDAAYKAVDLIVK P TLLEY
Sbjct: 460 WQLQNVQVTCGSLGLSTATVKLIDADGKEHISCSVGTGPVDAAYKAVDLIVKIPVTLLEY 519
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
SMNAVT+GIDAIA+TRVLIRG+N ++ST+A+TGE+V RTFSGTGA MDIV+SSV+AY+GA
Sbjct: 520 SMNAVTQGIDAIASTRVLIRGENGHTSTHALTGETVHRTFSGTGADMDIVISSVRAYIGA 579
Query: 543 LNKM 554
LNKM
Sbjct: 580 LNKM 583
[12][TOP]
>UniRef100_UPI0001983443 PREDICTED: similar to putative isopropylmalate synthase n=1
Tax=Vitis vinifera RepID=UPI0001983443
Length = 615
Score = 283 bits (723), Expect = 8e-75
Identities = 136/184 (73%), Positives = 164/184 (89%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHALK RL ELGY ++ +L ++FWRFK VAE+KK +TD D+IALVSDE+FQP+
Sbjct: 412 KLSGRHALKSRLLELGYEIEGMELDDIFWRFKEVAEKKKNLTDVDVIALVSDEIFQPKVF 471
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
WKL D+Q+TCGTLGLST+TVKL D+DG++HVACSVGTGPVD+AYKA+DL+VKE TLLEY
Sbjct: 472 WKLGDLQVTCGTLGLSTATVKLIDADGQKHVACSVGTGPVDSAYKAIDLLVKEQVTLLEY 531
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
+NAVTEGIDAIATTRVLIRG+ N++ TNA+TGE+V R+FSGTGAGMDIVVSSV+AY+ A
Sbjct: 532 GLNAVTEGIDAIATTRVLIRGEKNHTLTNALTGETVHRSFSGTGAGMDIVVSSVRAYISA 591
Query: 543 LNKM 554
LNKM
Sbjct: 592 LNKM 595
[13][TOP]
>UniRef100_A7QS57 Chromosome chr5 scaffold_156, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7QS57_VITVI
Length = 447
Score = 283 bits (723), Expect = 8e-75
Identities = 136/184 (73%), Positives = 164/184 (89%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHALK RL ELGY ++ +L ++FWRFK VAE+KK +TD D+IALVSDE+FQP+
Sbjct: 244 KLSGRHALKSRLLELGYEIEGMELDDIFWRFKEVAEKKKNLTDVDVIALVSDEIFQPKVF 303
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
WKL D+Q+TCGTLGLST+TVKL D+DG++HVACSVGTGPVD+AYKA+DL+VKE TLLEY
Sbjct: 304 WKLGDLQVTCGTLGLSTATVKLIDADGQKHVACSVGTGPVDSAYKAIDLLVKEQVTLLEY 363
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
+NAVTEGIDAIATTRVLIRG+ N++ TNA+TGE+V R+FSGTGAGMDIVVSSV+AY+ A
Sbjct: 364 GLNAVTEGIDAIATTRVLIRGEKNHTLTNALTGETVHRSFSGTGAGMDIVVSSVRAYISA 423
Query: 543 LNKM 554
LNKM
Sbjct: 424 LNKM 427
[14][TOP]
>UniRef100_O04974 2-isopropylmalate synthase B n=1 Tax=Solanum pennellii
RepID=LEU1B_SOLPN
Length = 612
Score = 274 bits (700), Expect = 4e-72
Identities = 132/184 (71%), Positives = 165/184 (89%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSG K ++ ELGY ++ +L +LFWRFK+VAE+KK++TD DL+AL+SDEVFQP+ V
Sbjct: 410 KLSGVMLCKPKMLELGYEIEGKELDDLFWRFKSVAEKKKKITDDDLVALMSDEVFQPQFV 469
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
W+L ++Q+TCG+LGLST+TVKL D+DG+EH++CSVGTGPVDAAYKAVDLIVK P TLLEY
Sbjct: 470 WQLQNVQVTCGSLGLSTATVKLIDADGREHISCSVGTGPVDAAYKAVDLIVKVPVTLLEY 529
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
SMNAVT+GIDAIA+TRVLIRG+N ++ST+A+TGE+V RTFSGTGA MDIV+SSV+AYVGA
Sbjct: 530 SMNAVTQGIDAIASTRVLIRGENGHTSTHALTGETVHRTFSGTGADMDIVISSVRAYVGA 589
Query: 543 LNKM 554
LNKM
Sbjct: 590 LNKM 593
[15][TOP]
>UniRef100_O04973 2-isopropylmalate synthase A n=1 Tax=Solanum pennellii
RepID=LEU1A_SOLPN
Length = 589
Score = 263 bits (673), Expect = 5e-69
Identities = 129/184 (70%), Positives = 157/184 (85%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHALK ++ ELGY +D +L +LFWRFK+VAE+KK++TD DLIAL+SDEV QP
Sbjct: 387 KLSGRHALKSKMLELGYDIDGKELEDLFWRFKSVAEKKKKITDDDLIALMSDEVLQPNVY 446
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
WKL D+QI CG+LGLST+TVKL ++DG+EH+ACSVGTGPVDAAYKAVDLIVK P TLLEY
Sbjct: 447 WKLGDVQIMCGSLGLSTATVKLINTDGQEHIACSVGTGPVDAAYKAVDLIVKVPITLLEY 506
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
SMNAVTEGIDAIA+TRV I + ++ N TG+++ RTFSGTGA MD+V+SSV+AY+GA
Sbjct: 507 SMNAVTEGIDAIASTRVSICSIDRHTIMNGSTGQTIHRTFSGTGADMDVVISSVRAYIGA 566
Query: 543 LNKM 554
LNKM
Sbjct: 567 LNKM 570
[16][TOP]
>UniRef100_B6SWN1 2-isopropylmalate synthase B n=1 Tax=Zea mays RepID=B6SWN1_MAIZE
Length = 642
Score = 239 bits (611), Expect = 8e-62
Identities = 118/184 (64%), Positives = 147/184 (79%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHA++ +L ELGY + D + + F R+K VAE+KKRVTD D+ AL+SDE+FQP+ +
Sbjct: 435 KLSGRHAVRSKLVELGYEISDKEFEDFFKRYKEVAEKKKRVTDEDIEALLSDEIFQPKVI 494
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
W L D+Q TCGTLGLST+TVKL DG+E +ACSVGTGPVDAAYKAVD I++ P L EY
Sbjct: 495 WSLADVQATCGTLGLSTATVKLIGPDGEERIACSVGTGPVDAAYKAVDQIIQIPTVLREY 554
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
M +VTEGIDAIATTRV++ GD +S +A+TG S R+FSG+GA MDIVVSSV+AY+ A
Sbjct: 555 GMTSVTEGIDAIATTRVVVTGDVANNSKHALTGHSFNRSFSGSGAAMDIVVSSVRAYLSA 614
Query: 543 LNKM 554
LNKM
Sbjct: 615 LNKM 618
[17][TOP]
>UniRef100_C5Y4G6 Putative uncharacterized protein Sb05g002540 n=1 Tax=Sorghum
bicolor RepID=C5Y4G6_SORBI
Length = 620
Score = 239 bits (609), Expect = 1e-61
Identities = 117/184 (63%), Positives = 147/184 (79%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHA++ +L ELGY + D + + F R+K VAE+KKRVTD D+ AL+SDE+FQP+ +
Sbjct: 414 KLSGRHAVRSKLVELGYEISDKEFEDFFKRYKEVAEKKKRVTDEDIEALLSDEIFQPKVI 473
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
W L D+Q TCGTLGLST+TVKL DG+E + CSVGTGPVDAAYKAVD I++ P L EY
Sbjct: 474 WSLADVQATCGTLGLSTATVKLIAPDGEEKIGCSVGTGPVDAAYKAVDQIIQIPTVLREY 533
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
M +VTEGIDAIATTRV++ GD +S +A+TG+S R+FSG+GA MDIVVSSV+AY+ A
Sbjct: 534 GMTSVTEGIDAIATTRVVVTGDVTNNSKHALTGQSFNRSFSGSGAAMDIVVSSVRAYLSA 593
Query: 543 LNKM 554
LNKM
Sbjct: 594 LNKM 597
[18][TOP]
>UniRef100_C4J3S6 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=C4J3S6_MAIZE
Length = 640
Score = 238 bits (608), Expect = 2e-61
Identities = 116/184 (63%), Positives = 147/184 (79%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHA++ +L ELGY + D + + F R+K VAE+KKRVTD D+ AL+SDE+FQP+ +
Sbjct: 434 KLSGRHAVRSKLVELGYEISDKEFEDFFKRYKEVAEKKKRVTDEDIEALLSDEIFQPKVI 493
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
W L D+Q TCGTLGLST+TVKL DG+E +ACSVGTGPVDAAYKA+D I++ P L EY
Sbjct: 494 WSLADVQATCGTLGLSTATVKLIAPDGEERIACSVGTGPVDAAYKAIDQIIQIPTVLREY 553
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
M +VTEGIDAIATTRV++ GD +S +A+TG + R+FSG+GA MDIVVSSV+AY+ A
Sbjct: 554 GMTSVTEGIDAIATTRVVVTGDVTNNSKHALTGRAFNRSFSGSGAAMDIVVSSVRAYLSA 613
Query: 543 LNKM 554
LNKM
Sbjct: 614 LNKM 617
[19][TOP]
>UniRef100_B6SWM0 2-isopropylmalate synthase B n=1 Tax=Zea mays RepID=B6SWM0_MAIZE
Length = 640
Score = 238 bits (608), Expect = 2e-61
Identities = 116/184 (63%), Positives = 147/184 (79%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHA++ +L ELGY + D + + F R+K VAE+KKRVTD D+ AL+SDE+FQP+ +
Sbjct: 434 KLSGRHAVRSKLVELGYEISDKEFEDFFKRYKEVAEKKKRVTDEDIEALLSDEIFQPKVI 493
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
W L D+Q TCGTLGLST+TVKL DG+E +ACSVGTGPVDAAYKA+D I++ P L EY
Sbjct: 494 WSLADVQATCGTLGLSTATVKLIAPDGEERIACSVGTGPVDAAYKAIDQIIQIPTVLREY 553
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
M +VTEGIDAIATTRV++ GD +S +A+TG + R+FSG+GA MDIVVSSV+AY+ A
Sbjct: 554 GMTSVTEGIDAIATTRVVVTGDVTNNSKHALTGRAFNRSFSGSGAAMDIVVSSVRAYLSA 613
Query: 543 LNKM 554
LNKM
Sbjct: 614 LNKM 617
[20][TOP]
>UniRef100_C0P8I4 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=C0P8I4_MAIZE
Length = 626
Score = 238 bits (607), Expect = 2e-61
Identities = 117/184 (63%), Positives = 149/184 (80%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHA++ +L ELGY + D + + F R+K VAE+KKRVTD DL AL+SDE+FQP+ +
Sbjct: 420 KLSGRHAVRSKLVELGYEIGDKEFEDFFKRYKEVAEKKKRVTDEDLEALLSDEIFQPKVI 479
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
W L D+Q TCGTL LST+TVKL DG+E +ACSVGTGPVDAAYKAVD I++ P L EY
Sbjct: 480 WSLADVQATCGTLALSTATVKLVAPDGEEKIACSVGTGPVDAAYKAVDKIIQIPTVLREY 539
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
SM +VTEGIDAIATTRV++ GD + ++ +A+TG+S R+FSG+GA MDIVVSSV+AY+ A
Sbjct: 540 SMTSVTEGIDAIATTRVVVTGDVSNNAKHALTGQSFNRSFSGSGASMDIVVSSVRAYLSA 599
Query: 543 LNKM 554
LNK+
Sbjct: 600 LNKI 603
[21][TOP]
>UniRef100_C5YQI8 Putative uncharacterized protein Sb08g001160 n=1 Tax=Sorghum
bicolor RepID=C5YQI8_SORBI
Length = 633
Score = 238 bits (606), Expect = 3e-61
Identities = 117/184 (63%), Positives = 148/184 (80%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHA++ +L ELGY + D + + F R+K VAE+KKRVTD DL AL+SDE+FQP+ +
Sbjct: 427 KLSGRHAVRSKLVELGYEIGDKEFEDFFKRYKEVAEKKKRVTDEDLEALLSDEIFQPKLI 486
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
W L D+Q TCGTL LST+TVKL DG+E +ACSVGTGPVDAAYKAVD I++ P L EY
Sbjct: 487 WSLADVQATCGTLSLSTATVKLIGPDGEERIACSVGTGPVDAAYKAVDQIIQIPTVLREY 546
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
SM +VTEGIDAIATTRV++ GD + ++ +A+TG S R+FSG+GA MDIVVSSV+AY+ A
Sbjct: 547 SMTSVTEGIDAIATTRVVVTGDVSINAKHALTGRSFNRSFSGSGASMDIVVSSVRAYLSA 606
Query: 543 LNKM 554
LNK+
Sbjct: 607 LNKI 610
[22][TOP]
>UniRef100_B8A2E9 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=B8A2E9_MAIZE
Length = 641
Score = 238 bits (606), Expect = 3e-61
Identities = 117/184 (63%), Positives = 147/184 (79%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHA++ +L ELGY + D + + F R+K VAE+KKRVTD D+ AL+SDE+FQP+ +
Sbjct: 434 KLSGRHAVRSKLVELGYEISDKEFEDFFKRYKEVAEKKKRVTDEDIEALLSDEIFQPKVI 493
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
W L D+Q TCGTLGLST+TVKL DG+E +ACSVGTGPVDAA+KAVD I++ P L EY
Sbjct: 494 WSLADVQATCGTLGLSTATVKLIGPDGEERIACSVGTGPVDAAHKAVDQIIQIPTVLREY 553
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
M +VTEGIDAIATTRV++ GD +S +A+TG S R+FSG+GA MDIVVSSV+AY+ A
Sbjct: 554 GMTSVTEGIDAIATTRVVVTGDVANNSKHALTGHSFNRSFSGSGAAMDIVVSSVRAYLSA 613
Query: 543 LNKM 554
LNKM
Sbjct: 614 LNKM 617
[23][TOP]
>UniRef100_B6SH97 2-isopropylmalate synthase B n=1 Tax=Zea mays RepID=B6SH97_MAIZE
Length = 624
Score = 238 bits (606), Expect = 3e-61
Identities = 117/184 (63%), Positives = 149/184 (80%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHA++ +L ELGY + D + + F R+K VAE+KKRVTD DL AL+SDE+FQP+ +
Sbjct: 418 KLSGRHAVRSKLVELGYEIGDKEFEDFFKRYKEVAEKKKRVTDEDLEALLSDEIFQPKVI 477
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
W L D+Q TCGTL LST+TVKL DG+E +ACSVGTGPVDAAYKAVD I++ P L EY
Sbjct: 478 WSLADVQATCGTLALSTATVKLIAPDGEEKIACSVGTGPVDAAYKAVDKIIQIPTVLREY 537
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
SM +VTEGIDAIATTRV++ GD + ++ +A+TG+S R+FSG+GA MDIVVSSV+AY+ A
Sbjct: 538 SMTSVTEGIDAIATTRVVVTGDVSNNAKHALTGQSFNRSFSGSGASMDIVVSSVRAYLSA 597
Query: 543 LNKM 554
LNK+
Sbjct: 598 LNKI 601
[24][TOP]
>UniRef100_A9T9B8 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9T9B8_PHYPA
Length = 583
Score = 235 bits (600), Expect = 1e-60
Identities = 122/184 (66%), Positives = 143/184 (77%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHALK RLN+LGY +D L ++F RFKAVAE+KK V+D DL L+SDEVFQPE +
Sbjct: 375 KLSGRHALKQRLNQLGYEIDGQDLDDVFKRFKAVAEKKKNVSDDDLEILLSDEVFQPETL 434
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
W + +Q+ CGT GLST+TVKL DG EH+ SVGTGPVDAAYKAVD IVK P TLLEY
Sbjct: 435 WSVGLIQVVCGTSGLSTATVKLVGPDGVEHIGMSVGTGPVDAAYKAVDTIVKAPVTLLEY 494
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
SM+AVTEGIDAIA TRV IR + + TN TG V R++SGTGA D+VVSSV+AY+ A
Sbjct: 495 SMHAVTEGIDAIAHTRVQIRALDPLTVTNPQTGSQVPRSYSGTGAAEDVVVSSVRAYISA 554
Query: 543 LNKM 554
LNKM
Sbjct: 555 LNKM 558
[25][TOP]
>UniRef100_Q2RAP8 2-isopropylmalate synthase B, putative, expressed n=1 Tax=Oryza
sativa Japonica Group RepID=Q2RAP8_ORYSJ
Length = 635
Score = 232 bits (592), Expect = 1e-59
Identities = 117/184 (63%), Positives = 146/184 (79%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHA++ +L ELGY + D + + F R+K VAE+KKRVTD D+ AL+SDE+FQP+
Sbjct: 430 KLSGRHAVRSKLVELGYEITDKEFEDFFKRYKEVAEKKKRVTDEDIEALLSDEIFQPKVF 489
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
W L D+Q TCGTLGLST+TVKL DG+E +AC+VGTGPVDAAYKAVD I++ P L EY
Sbjct: 490 WSLADVQATCGTLGLSTATVKLIGPDGEEKIACAVGTGPVDAAYKAVDDIIQIPTVLREY 549
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
SM +VTEGIDAIATTRV++ GD + S +A+TG S R FSG+GA +DIVVSSV+AY+ A
Sbjct: 550 SMTSVTEGIDAIATTRVVVTGDVS-DSKHALTGHSFSRAFSGSGAALDIVVSSVRAYLSA 608
Query: 543 LNKM 554
LNKM
Sbjct: 609 LNKM 612
[26][TOP]
>UniRef100_B8BJ19 Putative uncharacterized protein n=1 Tax=Oryza sativa Indica Group
RepID=B8BJ19_ORYSI
Length = 609
Score = 232 bits (592), Expect = 1e-59
Identities = 117/184 (63%), Positives = 146/184 (79%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHA++ +L ELGY + D + + F R+K VAE+KKRVTD D+ AL+SDE+FQP+
Sbjct: 404 KLSGRHAVRSKLVELGYEITDKEFEDFFKRYKEVAEKKKRVTDEDIEALLSDEIFQPKVF 463
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
W L D+Q TCGTLGLST+TVKL DG+E +AC+VGTGPVDAAYKAVD I++ P L EY
Sbjct: 464 WSLADVQATCGTLGLSTATVKLIGPDGEEKIACAVGTGPVDAAYKAVDDIIQIPTVLREY 523
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
SM +VTEGIDAIATTRV++ GD + S +A+TG S R FSG+GA +DIVVSSV+AY+ A
Sbjct: 524 SMTSVTEGIDAIATTRVVVTGDVS-DSKHALTGHSFSRAFSGSGAALDIVVSSVRAYLSA 582
Query: 543 LNKM 554
LNKM
Sbjct: 583 LNKM 586
[27][TOP]
>UniRef100_Q2QXY9 Os12g0138900 protein n=2 Tax=Oryza sativa RepID=Q2QXY9_ORYSJ
Length = 635
Score = 231 bits (590), Expect = 2e-59
Identities = 117/184 (63%), Positives = 145/184 (78%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHA++ +L ELGY + D + + F R+K VAE+KKRVTD D+ AL+SDE+FQP+
Sbjct: 430 KLSGRHAVRSKLVELGYEITDKEFEDFFKRYKEVAEKKKRVTDEDIEALLSDEIFQPKVF 489
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
W L D+Q TCGTLGLST+TVKL DG E +AC+VGTGPVDAAYKAVD I++ P L EY
Sbjct: 490 WSLADVQATCGTLGLSTATVKLIGPDGDEKIACAVGTGPVDAAYKAVDDIIQIPTVLREY 549
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
SM +VTEGIDAIATTRV++ GD + S +A+TG S R FSG+GA +DIVVSSV+AY+ A
Sbjct: 550 SMTSVTEGIDAIATTRVVVTGDVS-DSKHALTGHSFNRAFSGSGAALDIVVSSVRAYLSA 608
Query: 543 LNKM 554
LNKM
Sbjct: 609 LNKM 612
[28][TOP]
>UniRef100_A9S4K9 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9S4K9_PHYPA
Length = 616
Score = 227 bits (578), Expect = 5e-58
Identities = 115/184 (62%), Positives = 142/184 (77%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHALK RLN+LGY +D +L ++F RFKAVAE+KK V++ DL L+ DEVFQPE +
Sbjct: 408 KLSGRHALKQRLNQLGYEVDGQELDDVFKRFKAVAEKKKNVSNEDLETLLFDEVFQPETL 467
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
W L +Q+ CG G+ST+TVKL DG +H+ SVGTGPVDAAYKAVD IVK P TLLEY
Sbjct: 468 WSLGLIQVVCGNAGISTATVKLEGPDGAQHIGMSVGTGPVDAAYKAVDTIVKAPVTLLEY 527
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+N+VTEGIDA+A TRV IR ++ + T+A T V RT+SGTGA D+VVSS +AY+ A
Sbjct: 528 SLNSVTEGIDALAHTRVQIRALDSLTVTHAQTDSQVPRTYSGTGASEDVVVSSCRAYISA 587
Query: 543 LNKM 554
LNKM
Sbjct: 588 LNKM 591
[29][TOP]
>UniRef100_Q39891 Probable 2-isopropylmalate synthase n=1 Tax=Glycine max
RepID=LEU1_SOYBN
Length = 565
Score = 216 bits (551), Expect = 7e-55
Identities = 108/184 (58%), Positives = 142/184 (77%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSG AL+ RL ELGY L + ++ ++FW+FKA+AE+KK VTD DL ALVS + F E++
Sbjct: 372 KLSGSQALRKRLEELGYDLKEDEVDSVFWQFKAMAEKKKVVTDVDLKALVSYKAFHAESI 431
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
WKL D+Q+TCGT+GLST+TVKL + DG HVACS+G G VD+ YKA++LIVKEP LL+Y
Sbjct: 432 WKLGDLQVTCGTIGLSTATVKLVNIDGSTHVACSIGIGAVDSTYKAINLIVKEPTKLLDY 491
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+N+VTEGI T RV+I +NN++ST A T ++ TFSG A MD+VVS+VKAY+ A
Sbjct: 492 SLNSVTEGIGVNVTARVVICRENNHTSTYAFTEDANYPTFSGIAAEMDVVVSTVKAYLVA 551
Query: 543 LNKM 554
LNK+
Sbjct: 552 LNKL 555
[30][TOP]
>UniRef100_UPI0000DD9B13 Os11g0142500 n=1 Tax=Oryza sativa Japonica Group
RepID=UPI0000DD9B13
Length = 639
Score = 214 bits (545), Expect = 3e-54
Identities = 108/170 (63%), Positives = 134/170 (78%)
Frame = +3
Query: 45 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 224
LGY + D + + F R+K VAE+KKRVTD D+ AL+SDE+FQP+ W L D+Q TCGTLG
Sbjct: 448 LGYEITDKEFEDFFKRYKEVAEKKKRVTDEDIEALLSDEIFQPKVFWSLADVQATCGTLG 507
Query: 225 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 404
LST+TVKL DG+E +AC+VGTGPVDAAYKAVD I++ P L EYSM +VTEGIDAIAT
Sbjct: 508 LSTATVKLIGPDGEEKIACAVGTGPVDAAYKAVDDIIQIPTVLREYSMTSVTEGIDAIAT 567
Query: 405 TRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGALNKM 554
TRV++ GD + S +A+TG S R FSG+GA +DIVVSSV+AY+ ALNKM
Sbjct: 568 TRVVVTGDVS-DSKHALTGHSFSRAFSGSGAALDIVVSSVRAYLSALNKM 616
[31][TOP]
>UniRef100_A8HXS9 Isopropylmalate synthase (Fragment) n=1 Tax=Chlamydomonas
reinhardtii RepID=A8HXS9_CHLRE
Length = 444
Score = 194 bits (492), Expect = 5e-48
Identities = 99/188 (52%), Positives = 138/188 (73%), Gaps = 4/188 (2%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR+AL RL LGY L +L ++F RFKA+A++KK +TD D++AL+SDE+ QP+ +
Sbjct: 239 KHSGRNALNSRLRTLGYELSQSELDDVFKRFKALADKKKGITDEDILALMSDELHQPKVI 298
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
W+LLD+Q+ CGT+G+ T+TV++ DG + VGTGPVDAAYKAVD +V+ A L +Y
Sbjct: 299 WELLDLQVVCGTMGMPTATVQMKGPDGIARIGVGVGTGPVDAAYKAVDSLVRVEAELSDY 358
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYS----STNAVTGESVERTFSGTGAGMDIVVSSVKA 530
S+++VT+GI+A+A TRV+IR S S +A G +V+R FSG+GA DIVV+S +A
Sbjct: 359 SVSSVTQGIEALAHTRVMIRPSGKMSDAGYSEHAALG-TVQRQFSGSGANEDIVVASARA 417
Query: 531 YVGALNKM 554
YV ALNKM
Sbjct: 418 YVSALNKM 425
[32][TOP]
>UniRef100_Q6UA13 Fiber protein Fb26 (Fragment) n=1 Tax=Gossypium barbadense
RepID=Q6UA13_GOSBA
Length = 128
Score = 176 bits (446), Expect = 1e-42
Identities = 88/108 (81%), Positives = 98/108 (90%)
Frame = +3
Query: 231 TSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIATTR 410
T+TVKL +DG+EHVACSVGTGPVD+AYKA+DLI KEP TLLEYSMNAVTEGIDAIATTR
Sbjct: 1 TATVKLIGADGEEHVACSVGTGPVDSAYKAIDLITKEPVTLLEYSMNAVTEGIDAIATTR 60
Query: 411 VLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGALNKM 554
VLIR + + STN +TGE V+RTFSGTGAGMDIVVSSVKAY+GALNKM
Sbjct: 61 VLIRAEKSRISTNILTGEIVQRTFSGTGAGMDIVVSSVKAYIGALNKM 108
[33][TOP]
>UniRef100_A9GW82 2-isopropylmalate synthase n=1 Tax=Sorangium cellulosum 'So ce 56'
RepID=A9GW82_SORC5
Length = 564
Score = 174 bits (442), Expect = 3e-42
Identities = 92/184 (50%), Positives = 128/184 (69%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHAL++RL ELGY LD+ QL+ F FKA+A++KK VTD D+ A+VS Q + +
Sbjct: 352 KHSGRHALRNRLEELGYHLDEAQLAAAFASFKALADKKKHVTDPDIEAIVSTTRAQADDL 411
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+ L +Q+ CGT G+ T+TV+L DG HV ++GTGPVDAAY+A+D IV+ P++LLE+
Sbjct: 412 YTLDALQVACGTTGMPTATVRLRGPDGALHVRAAIGTGPVDAAYRAIDEIVRVPSSLLEF 471
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S++AVTEGIDA+ V +R D SS ++ R F G GA DI+V+S KAY+ A
Sbjct: 472 SVHAVTEGIDALGEVSVRVRADAT-SSKRHPQHDAAARVFHGHGADTDILVASAKAYLTA 530
Query: 543 LNKM 554
LN++
Sbjct: 531 LNRL 534
[34][TOP]
>UniRef100_C1FID7 2-isopropylmalate synthase n=1 Tax=Micromonas sp. RCC299
RepID=C1FID7_9CHLO
Length = 639
Score = 166 bits (419), Expect = 1e-39
Identities = 93/194 (47%), Positives = 126/194 (64%), Gaps = 10/194 (5%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKR-VTDADLIALVSDEVFQPE- 176
K SGRHALK +L +LG+ L+ +L+ +F RFK VAEQK V D ++IALV+ Q +
Sbjct: 415 KHSGRHALKSKLKQLGFPLEGDELNEMFDRFKLVAEQKTGGVGDDEIIALVTSGAGQGDD 474
Query: 177 --AVWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPAT 350
WKL ++Q+ CGT+GL T+TVK+ D + +VGTGPVDAAYKA+D + +
Sbjct: 475 TAVTWKLDEVQVVCGTMGLPTATVKMTGPDAVTRINSAVGTGPVDAAYKAIDGLCRVKVD 534
Query: 351 LLEYSMNAVTEGIDAIATTRVLIRGDNNYS------STNAVTGESVERTFSGTGAGMDIV 512
L+EY++NAV EGI+++A TRV IR ++ + N TG RTF TGA DIV
Sbjct: 535 LVEYTVNAVVEGIESLAQTRVSIRAKSDQTMPGAMMKANVQTGNVEARTFMATGADSDIV 594
Query: 513 VSSVKAYVGALNKM 554
VSS +AYV ALN+M
Sbjct: 595 VSSARAYVAALNRM 608
[35][TOP]
>UniRef100_C1N4J5 2-isopropylmalate synthase n=1 Tax=Micromonas pusilla CCMP1545
RepID=C1N4J5_9CHLO
Length = 649
Score = 162 bits (410), Expect = 2e-38
Identities = 92/192 (47%), Positives = 123/192 (64%), Gaps = 8/192 (4%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKR-VTDADLIALVSDEVFQ--- 170
K SGRHAL +L +LGY L+ L +F RFK VAEQK V D ++IALV+ E Q
Sbjct: 427 KHSGRHALSSKLKQLGYPLEGDALDEMFNRFKLVAEQKTGGVDDDEIIALVTCEGSQFAG 486
Query: 171 ---PEAVWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVD-LIVK 338
A WKL D+Q+ CGT+GL T+TVK+ DG V VG+GPVDA YKA+D ++
Sbjct: 487 DVDKSASWKLEDVQVVCGTMGLPTATVKMCGPDGMSRVRSEVGSGPVDATYKAIDGIVAA 546
Query: 339 EPATLLEYSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVS 518
L+EYS+NAV EGI+++A TRV +R ++ + +GE RTF+ +GA DIVV+
Sbjct: 547 GKVELVEYSVNAVVEGIESLAETRVRVRPMDSVAMKAKSSGEMEARTFTASGADTDIVVA 606
Query: 519 SVKAYVGALNKM 554
S +AYV A N+M
Sbjct: 607 SARAYVAATNRM 618
[36][TOP]
>UniRef100_B7FUP6 2-isopropylmalate synthase n=1 Tax=Phaeodactylum tricornutum CCAP
1055/1 RepID=B7FUP6_PHATR
Length = 663
Score = 160 bits (405), Expect = 6e-38
Identities = 91/189 (48%), Positives = 122/189 (64%), Gaps = 5/189 (2%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKR-VTDADLIALVSDEVFQPEA 179
K SGR+A+ RL ELGY LD +L+ +F RFK VAE+KK + D DL ALVSD+
Sbjct: 438 KHSGRNAVGTRLRELGYDLDTEKLNAVFVRFKQVAERKKGGLEDEDLEALVSDQAGLSNL 497
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
+W++ +Q+ G G+ T+TVK+ DG E GTGPVDA YKA+D I+ L
Sbjct: 498 LWEVTGLQVATGLSGIPTATVKMLGPDGLERYVACTGTGPVDAVYKAIDQIMGVSVRLEA 557
Query: 360 YSMNAVTEGIDAIATTRVLIR----GDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVK 527
Y +N+VTEGI+A+ATTRV+I G N+ S ++ TG S R FSG+G+ DI+ SS +
Sbjct: 558 YQLNSVTEGIEAMATTRVVIAPLEGGPNDSISIHSQTGVSRNRKFSGSGSDTDIITSSAR 617
Query: 528 AYVGALNKM 554
AYV ALNK+
Sbjct: 618 AYVSALNKL 626
[37][TOP]
>UniRef100_B8BRI7 Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335
RepID=B8BRI7_THAPS
Length = 658
Score = 157 bits (397), Expect = 5e-37
Identities = 90/189 (47%), Positives = 121/189 (64%), Gaps = 5/189 (2%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKR-VTDADLIALVSDEVFQPEA 179
K SGR+A+ RL E+GY LD +L+ +F RFK VAE+KK + D DL +LV D+
Sbjct: 434 KHSGRNAVGTRLREMGYDLDMDKLNAVFARFKEVAEKKKGGLDDDDLESLVMDQSQSTNE 493
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
+WK+ +Q T G G+ TSTVK+ DG E + GTGPVDA YKA+D I+ L
Sbjct: 494 LWKVTGLQTTTGISGIPTSTVKMMGPDGVERFVSATGTGPVDAVYKAIDQIMGVSVELES 553
Query: 360 YSMNAVTEGIDAIATTRVLI----RGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVK 527
YSMN+V EGI+A+A+TRV+I G N+ +A T + ER FSG+G+ DI+ SS +
Sbjct: 554 YSMNSVNEGIEALASTRVVIVPNANGPNDSVVMDAQTSQLRERKFSGSGSDTDIITSSAR 613
Query: 528 AYVGALNKM 554
AYV ALNK+
Sbjct: 614 AYVSALNKL 622
[38][TOP]
>UniRef100_Q01FR2 Putative 2-isopropylmalate synthase (ISS) n=1 Tax=Ostreococcus
tauri RepID=Q01FR2_OSTTA
Length = 586
Score = 155 bits (393), Expect = 1e-36
Identities = 88/194 (45%), Positives = 120/194 (61%), Gaps = 10/194 (5%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKR-VTDADLIALVSDEVFQPEA 179
K SGRHAL +L +LG ++ L +F RFK VAE K V D +L+A+V D +
Sbjct: 378 KHSGRHALSSKLKQLGVPMEGAALDEVFNRFKLVAETKLGGVNDDELLAIVRDGESVQDP 437
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
W L +Q+ CGT GL T+TV++ + DG +H++ VGTGPVDAA+KA+D +V L E
Sbjct: 438 AWSLETVQVVCGTTGLPTATVRMNNRDGTQHISAVVGTGPVDAAFKAIDALVGLDVVLTE 497
Query: 360 YSMNAVTEGIDAIATTRVLIR---------GDNNYSSTNAVTGESVERTFSGTGAGMDIV 512
Y + AVT+GI+++A T + I+ G + Y TN TGE R F+ TGA DIV
Sbjct: 498 YRVTAVTKGINSMAETTITIKPKEGVEQKLGTDVY-KTNVQTGEKTMRAFTATGADTDIV 556
Query: 513 VSSVKAYVGALNKM 554
VSS +AYV ALN+M
Sbjct: 557 VSSARAYVIALNRM 570
[39][TOP]
>UniRef100_Q4BZE1 2-isopropylmalate synthase n=1 Tax=Crocosphaera watsonii WH 8501
RepID=Q4BZE1_CROWT
Length = 537
Score = 154 bits (390), Expect = 3e-36
Identities = 79/184 (42%), Positives = 120/184 (65%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR+A + RL+ELG+ L D L+N F RFK VA++KK +TD DL A+V+DE+ Q +
Sbjct: 347 KLSGRNAFRTRLSELGFELSDNDLNNAFLRFKEVADKKKEITDWDLEAIVNDEIQQAPEL 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG +ST+TV L + +GKE ++GTGPVDA YKA++ +V P L+E+
Sbjct: 407 FRLELVQVSCGDHAVSTATVTLRNPEGKELTDAAIGTGPVDAVYKAINRVVNVPNELIEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDA+ + +R + RT+SG A DI+ +S +AY+ A
Sbjct: 467 SVKSVTAGIDAMGEVTIRLRHEG--------------RTYSGYAANTDIITASARAYISA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[40][TOP]
>UniRef100_A4RRV6 Predicted protein n=1 Tax=Ostreococcus lucimarinus CCE9901
RepID=A4RRV6_OSTLU
Length = 624
Score = 154 bits (388), Expect = 6e-36
Identities = 86/193 (44%), Positives = 118/193 (61%), Gaps = 9/193 (4%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKR-VTDADLIALVSDEVFQPEA 179
K SGRHAL +L +LG ++ L +F RFK VAE K V D +L+A+V D +
Sbjct: 416 KHSGRHALSSKLKQLGVPMEGDALDEVFNRFKLVAETKLGGVNDDELLAIVRDGESVQDP 475
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
W L +Q+ CGT GL T+TVK+ DG H++ VGTGPVDAA+KA+D +V L E
Sbjct: 476 AWSLETVQVVCGTTGLPTATVKMLAKDGTVHISAVVGTGPVDAAFKAIDALVGLDVVLTE 535
Query: 360 YSMNAVTEGIDAIATTRVLIRGDN--------NYSSTNAVTGESVERTFSGTGAGMDIVV 515
Y + AVT+GI+++A T + ++ + TN TGE+ R+F+ TGA DIVV
Sbjct: 536 YRVTAVTKGINSLAETTITVKPREGAEQKLGADVFKTNLQTGETAVRSFTATGADTDIVV 595
Query: 516 SSVKAYVGALNKM 554
SS +AYV ALN+M
Sbjct: 596 SSARAYVIALNRM 608
[41][TOP]
>UniRef100_Q46K01 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus str.
NATL2A RepID=LEU1_PROMT
Length = 539
Score = 152 bits (385), Expect = 1e-35
Identities = 80/184 (43%), Positives = 122/184 (66%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL +LGY L+ L++ F RFK +A++K+ +TD DL A+VS++V PEA+
Sbjct: 347 KLSGRSAVRARLEDLGYDLNREDLNDAFARFKDLADRKREITDRDLEAIVSEQVQLPEAL 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CGT + T+TV + DG+E A S+GTGPVDA +A+D + +EP L+E+
Sbjct: 407 FQLKLVQVSCGTSLMPTATVTVVGEDGEEKTAVSLGTGPVDAVVRALDSLTEEPNELIEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VTEGIDA+ + IR D N FSG A D+VV++ +AY+ A
Sbjct: 467 SVKSVTEGIDALGEVTIRIRRDGN--------------LFSGHSADTDVVVAAAQAYINA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[42][TOP]
>UniRef100_A2C3L7 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus str.
NATL1A RepID=LEU1_PROM1
Length = 539
Score = 152 bits (385), Expect = 1e-35
Identities = 80/184 (43%), Positives = 122/184 (66%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL +LGY L+ L++ F RFK +A++K+ +TD DL A+VS++V PEA+
Sbjct: 347 KLSGRSAVRARLEDLGYDLNREDLNDAFARFKDLADRKREITDRDLEAIVSEQVQLPEAL 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CGT + T+TV + DG+E A S+GTGPVDA +A+D + +EP L+E+
Sbjct: 407 FQLKLVQVSCGTSLMPTATVTVVGEDGEEKTAVSLGTGPVDAVVRALDSLTEEPNELIEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VTEGIDA+ + IR D N FSG A D+VV++ +AY+ A
Sbjct: 467 SVKSVTEGIDALGEVTIRIRRDGN--------------LFSGHSADTDVVVAAAQAYINA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[43][TOP]
>UniRef100_Q7NI93 2-isopropylmalate synthase n=1 Tax=Gloeobacter violaceus
RepID=LEU1_GLOVI
Length = 538
Score = 152 bits (385), Expect = 1e-35
Identities = 81/184 (44%), Positives = 117/184 (63%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR+A + RL ELGY L D L+ F RFK +A++KK V+D D+ A++SDE+
Sbjct: 345 KHSGRNAFRTRLVELGYELGDADLNRAFLRFKELADKKKTVSDWDIEAVISDEIRLIPEA 404
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG GL T+TV+L DG E V +VGTGPVDA YKA++ +++ P L+E+
Sbjct: 405 YRLEQVQVSCGEPGLPTATVRLTGPDGVERVDAAVGTGPVDAVYKAINRLIELPNELIEF 464
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDA+ + +R D RTFSG A DI+V+S +AY+ A
Sbjct: 465 SVQSVTAGIDAMGEVTIRVRQDG--------------RTFSGHAANTDIIVASARAYLNA 510
Query: 543 LNKM 554
LNK+
Sbjct: 511 LNKL 514
[44][TOP]
>UniRef100_P48576 2-isopropylmalate synthase n=1 Tax=Synechocystis sp. PCC 6803
RepID=LEU1_SYNY3
Length = 533
Score = 151 bits (382), Expect = 3e-35
Identities = 82/184 (44%), Positives = 120/184 (65%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR+A RL ELG+ L D +L+N F RFK VA+++K +TD DL A+V+DE+ QP +
Sbjct: 347 KLSGRNAFGTRLKELGFDLSDTELNNAFIRFKEVADKRKEITDWDLEAIVNDEIRQPPEL 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG + T+T+ + G E A ++GTGPVDA YKA++ IV+ P LLEY
Sbjct: 407 FRLERVQVSCGEPSVPTATLTIRTPAGPEETAVAIGTGPVDAVYKAINQIVQLPNELLEY 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VTEGIDA+ V +R N V ++G A DI+V+S +AY+GA
Sbjct: 467 SVTSVTEGIDALGKVSVRLR-------HNGV-------IYTGYAANTDIIVASARAYLGA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[45][TOP]
>UniRef100_A9AZM4 2-isopropylmalate synthase n=1 Tax=Herpetosiphon aurantiacus ATCC
23779 RepID=A9AZM4_HERA2
Length = 555
Score = 149 bits (377), Expect = 1e-34
Identities = 75/185 (40%), Positives = 119/185 (64%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA + R+ ELGY D+ +++LF RFK VA++KK V D D+ AL+SDE +P V
Sbjct: 334 KHSGRHAFRHRVQELGYSFDEATINHLFARFKDVADRKKYVDDRDVEALISDEAGRPSPV 393
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q G + T+TV++ +G+ + + GTGPVDA Y A++ +V P TLLE+
Sbjct: 394 YELEHVQFASGVNAIPTATVRMRGPNGEVKIESAQGTGPVDAVYSAINKVVLTPVTLLEF 453
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVE-RTFSGTGAGMDIVVSSVKAYVG 539
++NA+TEGIDA+ V + + +T ++ + + + G G +DI+V++ +AYV
Sbjct: 454 AVNAITEGIDAVGEVSVKVVEGKHKHVRGVLTDKATDAKVWRGNGVNVDIIVAAAEAYVS 513
Query: 540 ALNKM 554
ALNK+
Sbjct: 514 ALNKL 518
[46][TOP]
>UniRef100_A3IRU3 2-isopropylmalate synthase n=1 Tax=Cyanothece sp. CCY0110
RepID=A3IRU3_9CHRO
Length = 537
Score = 149 bits (377), Expect = 1e-34
Identities = 77/184 (41%), Positives = 118/184 (64%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR+A + RLNELG+ L + +L+N F RFK VA++KK +TD DL A+V+DE+ Q +
Sbjct: 347 KLSGRNAFRTRLNELGFELSETELNNAFLRFKEVADKKKEITDWDLEAIVNDEIQQAPEL 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG T+TV L + +GKE ++GTGPVDA YKA++ +V P L+E+
Sbjct: 407 FRLELVQVSCGDHSAPTATVTLRNPEGKELTDAAIGTGPVDAVYKAINRVVNVPNELIEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDA+ + +R + R +SG A DI+ +S +AY+ A
Sbjct: 467 SVKSVTAGIDAMGEVTIRLRYEG--------------RIYSGYAANTDIITASARAYISA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[47][TOP]
>UniRef100_A9BB43 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus str. MIT
9211 RepID=LEU1_PROM4
Length = 536
Score = 149 bits (375), Expect = 2e-34
Identities = 80/184 (43%), Positives = 118/184 (64%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL ELGY L L+ F +FK +A++K+ +TD DL A+VS++V QP+A
Sbjct: 347 KLSGRSAVRARLEELGYDLTRDDLNEAFAKFKDLADRKREITDRDLEAIVSEQVMQPDAR 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CGT T+TV LAD DG E A ++GTGPVDA KA+D + E L+E+
Sbjct: 407 FQLQLVQVSCGTTLKPTATVTLADQDGTEQTAVALGTGPVDAVCKALDSLAGESNELIEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VTEGIDA+ + +R + + FSG A D+VV++ +AYV A
Sbjct: 467 SVKSVTEGIDALGEVTIRLRREG--------------KIFSGHSADTDVVVAAAQAYVNA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[48][TOP]
>UniRef100_Q7VBG1 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus
RepID=LEU1_PROMA
Length = 536
Score = 148 bits (374), Expect = 2e-34
Identities = 80/184 (43%), Positives = 119/184 (64%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL ELGY L L++ F RFK +A++K+ ++D DL A+VS++V QPEA
Sbjct: 347 KLSGRSAVRARLEELGYDLTREDLNDAFARFKDLADRKREISDRDLEAIVSEQVMQPEAR 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL +Q++CGT T+TV +AD DG E+ A ++GTGPVDA KA+ + E L+E+
Sbjct: 407 FKLHLVQVSCGTALRPTATVTIADQDGIENTAVALGTGPVDAVCKALRSLTNEKNDLIEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VTEGIDA+ + +R D + FSG A D+VV++ +AY+ A
Sbjct: 467 SVKSVTEGIDALGEVTIRLRRDG--------------KIFSGHSADTDVVVAAAQAYINA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[49][TOP]
>UniRef100_B7KJX8 2-isopropylmalate synthase n=1 Tax=Cyanothece sp. PCC 7424
RepID=LEU1_CYAP7
Length = 536
Score = 148 bits (374), Expect = 2e-34
Identities = 78/184 (42%), Positives = 116/184 (63%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHA RL ELG+ L + L+ F RFK VA++KK +TD DL A+V+DE+ Q V
Sbjct: 347 KLSGRHAFSTRLKELGFELSETDLNKAFLRFKEVADKKKEITDWDLEAIVNDEIQQAPEV 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG T+TV L +G+E + ++GTGPVDA YKA++ +V P L+E+
Sbjct: 407 FRLELVQVSCGDQARPTATVILRGPEGQELMDAAIGTGPVDAVYKAINRVVNVPNQLIEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDA+ + ++ +N R FSG A DI+V+S +AY+ A
Sbjct: 467 SVKSVTAGIDAMGEVTIRLKYEN--------------RIFSGHAANTDIIVASARAYISA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[50][TOP]
>UniRef100_A3Z7T3 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. RS9917
RepID=A3Z7T3_9SYNE
Length = 540
Score = 147 bits (371), Expect = 5e-34
Identities = 78/184 (42%), Positives = 119/184 (64%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL ELGY L L F RFK +A++K+ +TD DL A+VS++V QPEA
Sbjct: 347 KLSGRSAVRARLEELGYDLSREDLDEAFARFKDLADRKREITDRDLEAIVSEQVQQPEAR 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG+ T+TV LAD +G+E A ++GTGPVDA +A++ + +EP L+E+
Sbjct: 407 YQLKLVQVSCGSSLRPTATVTLADEEGREQTAAAIGTGPVDAVCRALNALAEEPNQLVEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VTEGIDA+ + +R D +SG A D+VV++ +A+V A
Sbjct: 467 SVKSVTEGIDAMGEVTIRLRRDG--------------ALYSGHSADTDVVVAAAQAFVNA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[51][TOP]
>UniRef100_B7JYP4 2-isopropylmalate synthase n=2 Tax=Cyanothece RepID=LEU1_CYAP8
Length = 536
Score = 147 bits (371), Expect = 5e-34
Identities = 75/184 (40%), Positives = 118/184 (64%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR+A + RL ELG+ L D +++N F RFK VA++KK +TD DL A+V+DE+ Q +
Sbjct: 347 KLSGRNAFRTRLKELGFELSDTEINNAFLRFKEVADKKKEITDWDLAAIVNDEMQQAPEL 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG T+TV L DG+E ++GTGPVDA YKA++ +V+ P L+E+
Sbjct: 407 FRLELVQVSCGDHACPTATVTLRTPDGQELTDAAIGTGPVDAVYKAINRVVQVPNELIEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDA+ + +R + ++ +SG A DI+ +S +AY+ A
Sbjct: 467 SVKSVTAGIDAMGEVTIRLRYE--------------DKIYSGYAANTDIITASARAYISA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[52][TOP]
>UniRef100_Q05XR9 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. RS9916
RepID=Q05XR9_9SYNE
Length = 540
Score = 146 bits (369), Expect = 9e-34
Identities = 79/184 (42%), Positives = 118/184 (64%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL ELGY L L F RFK +A++K+ +TD DL A+VS++V QPEA
Sbjct: 347 KLSGRSAVRARLEELGYDLSRDDLDEAFARFKDLADRKREITDRDLEAIVSEQVQQPEAR 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG+ T+TV LAD +G+E A S+GTGPVDA +A++ + P L+E+
Sbjct: 407 YQLKLVQVSCGSSLQPTATVTLADEEGQEQTAASIGTGPVDAVCRALNALAGVPNELVEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VTEGIDA+ + +R D + FSG A D+VV++ +A+V A
Sbjct: 467 SVKSVTEGIDAMGEVTIRLRRDG--------------QLFSGHSADTDVVVAAAQAFVNA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[53][TOP]
>UniRef100_B1WQQ4 2-isopropylmalate synthase n=1 Tax=Cyanothece sp. ATCC 51142
RepID=LEU1_CYAA5
Length = 537
Score = 146 bits (369), Expect = 9e-34
Identities = 76/184 (41%), Positives = 116/184 (63%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR+A + RL+ELG+ L + L+N F RFK VA++KK +TD DL A+V+DE+ Q +
Sbjct: 347 KLSGRNAFRTRLDELGFELSERDLNNAFLRFKEVADKKKEITDWDLEAIVNDEIQQAPEL 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG T+TV L +GKE ++GTGPVDA YKA++ +V P L+E+
Sbjct: 407 FRLELVQVSCGDHSAPTATVTLRTPEGKELTDAAIGTGPVDAVYKAINRVVNVPNELIEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDA+ + +R + R +SG A DI+ +S +AY+ A
Sbjct: 467 SVKSVTAGIDAMGEVTIRLRHEG--------------RIYSGYAANTDIITASARAYISA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[54][TOP]
>UniRef100_B4B3Y2 2-isopropylmalate synthase n=1 Tax=Cyanothece sp. PCC 7822
RepID=B4B3Y2_9CHRO
Length = 535
Score = 145 bits (367), Expect = 1e-33
Identities = 76/184 (41%), Positives = 118/184 (64%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR+A RL ELG+ L + +L+ F RFK VA+++K +TD DL A+V+DE+ +
Sbjct: 347 KLSGRNAFGTRLKELGFELTETELNKAFVRFKEVADKRKEITDWDLEAIVNDEIHVAPEI 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG T+TV L +G+E + ++GTGPVDA YKA++ +V P L+E+
Sbjct: 407 FRLELVQVSCGDQARPTATVILKGPNGEELMDAAIGTGPVDAVYKAINRVVNVPNQLIEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VTEGIDA+ + ++ +N RTFSG A DI+V+S +AY+ A
Sbjct: 467 SVKSVTEGIDAMGEVTIRLKYEN--------------RTFSGHAANTDIIVASARAYISA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[55][TOP]
>UniRef100_A2C859 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus str. MIT
9303 RepID=LEU1_PROM3
Length = 540
Score = 145 bits (366), Expect = 2e-33
Identities = 80/184 (43%), Positives = 118/184 (64%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL ELGY L L F RFK +A++K+ +TD DL A+VS++V QPEA
Sbjct: 347 KLSGRSAVRARLEELGYDLTREDLDEAFARFKDLADRKRDITDRDLEAIVSEQVQQPEAR 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG+ T+TV LA DG+E A +VGTGPVDA +A++ + EP L+E+
Sbjct: 407 FQLRLVQVSCGSSLRPTATVILAQEDGQEQTAAAVGTGPVDAVCRALNALAGEPNELIEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VTEGIDA+ + +R D + FSG A D+VV++ +A+V A
Sbjct: 467 SVKSVTEGIDAMGEVTIRLRRDG--------------QLFSGHSADTDVVVAAAQAFVNA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[56][TOP]
>UniRef100_Q2JLJ8 2-isopropylmalate synthase n=1 Tax=Synechococcus sp.
JA-2-3B'a(2-13) RepID=Q2JLJ8_SYNJB
Length = 546
Score = 145 bits (365), Expect = 3e-33
Identities = 77/184 (41%), Positives = 115/184 (62%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR+A ++RL ELG+ L + L+ F RFK +A++KK ++D DL A+V+DE +
Sbjct: 356 KHSGRNAFRNRLKELGFELSEQDLNKAFLRFKELADKKKEISDLDLEAIVNDETRPVPEL 415
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q+ CG T+TV+L +G+E V +VGTGPVDA YKA++ IV P L+E+
Sbjct: 416 YRLEHVQVVCGNREAPTATVRLVTPEGEERVDAAVGTGPVDAVYKAINRIVNIPNKLIEF 475
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDAI + +R + +R FSG A DI+V+S +AY+ A
Sbjct: 476 SVQSVTAGIDAIGEVTIRLRHE--------------DRIFSGHAANTDIIVASAQAYMNA 521
Query: 543 LNKM 554
LNK+
Sbjct: 522 LNKL 525
[57][TOP]
>UniRef100_B1XLQ9 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. PCC 7002
RepID=LEU1_SYNP2
Length = 533
Score = 144 bits (363), Expect = 4e-33
Identities = 77/184 (41%), Positives = 113/184 (61%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR+A + RL ELG+ L D L+ F RFK +A++KK +TD DL A+V DE QP +
Sbjct: 347 KHSGRNAFRTRLAELGFDLSDNDLNKAFLRFKDLADKKKEITDWDLEAIVKDETQQPPEL 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG T+T+ + GKE ++GTGPVDA YKA++ +V+ P L+EY
Sbjct: 407 FRLELVQVSCGDHAQPTATITIRTPGGKELTDAAIGTGPVDAIYKAINRVVQVPNELIEY 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDAI + +R + R +SG A DIVV+S +AY+ A
Sbjct: 467 SVQSVTAGIDAIGEVTIRLRHEG--------------RIYSGHAANTDIVVASARAYISA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[58][TOP]
>UniRef100_Q2JSL4 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. JA-3-3Ab
RepID=Q2JSL4_SYNJA
Length = 546
Score = 144 bits (362), Expect = 6e-33
Identities = 77/184 (41%), Positives = 114/184 (61%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR+A + RL ELG+ L + L+ F RFK +A++KK +TD DL A+V+DE +
Sbjct: 356 KHSGRNAFRTRLRELGFELSEQDLNKAFLRFKELADKKKEITDLDLEAIVNDETRPVPDL 415
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q+ CG T+TV+L +G+E V +VGTGPVDA YKA++ IV P L+E+
Sbjct: 416 YRLEHVQVVCGNHETPTATVRLITPEGEERVDAAVGTGPVDAVYKAINRIVNIPNKLIEF 475
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDA+ + +R + +R FSG A DI+V+S +AY+ A
Sbjct: 476 SVQSVTAGIDAMGEVTIRLRHE--------------DRVFSGHAANTDIIVASAQAYMNA 521
Query: 543 LNKM 554
LNK+
Sbjct: 522 LNKL 525
[59][TOP]
>UniRef100_A0ZGD0 2-isopropylmalate synthase n=1 Tax=Nodularia spumigena CCY9414
RepID=A0ZGD0_NODSP
Length = 534
Score = 144 bits (362), Expect = 6e-33
Identities = 77/184 (41%), Positives = 116/184 (63%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR+A + RL ELG+ L + +L+ F +FK VA++KK +TD DL A+V+DE+ Q +
Sbjct: 347 KHSGRNAFRSRLTELGFELSETELNKAFVKFKDVADKKKEITDWDLEAIVNDEIQQAPDL 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+++ +QI+CG T+TV L G+E ++GTGPVDA YKA++ +V P L+E+
Sbjct: 407 FRVELVQISCGNNAQPTATVTLRTPAGEELTDAAIGTGPVDAVYKAINRVVNVPNQLIEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VTEGIDA+ + +R D+ R FSG A DI+V+S +AYV A
Sbjct: 467 SVQSVTEGIDALGEVTIRLRHDS--------------RVFSGHAANTDIIVASAQAYVNA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[60][TOP]
>UniRef100_A4CVP9 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. WH 7805
RepID=A4CVP9_SYNPV
Length = 540
Score = 143 bits (361), Expect = 7e-33
Identities = 76/184 (41%), Positives = 118/184 (64%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL ELGY L L + F RFK +A++K+ +TD DL A+VS++V QP+A
Sbjct: 347 KLSGRSAVRARLEELGYDLSREDLDDAFARFKELADRKRDITDRDLEAIVSEQVQQPDAR 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG+ T+TV L D +G+E ++GTGPVDA +A++ + EP L+E+
Sbjct: 407 YQLTSVQVSCGSNLQPTATVTLLDEEGQEQSEAAIGTGPVDAVCRALNALAGEPNELVEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VTEGIDA+ + +R D + FSG A D+VV++ +A+V A
Sbjct: 467 SVKSVTEGIDAMGEVTIRLRRDG--------------QLFSGHAADTDVVVAAAQAFVNA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[61][TOP]
>UniRef100_B4VRZ4 2-isopropylmalate synthase n=1 Tax=Microcoleus chthonoplastes PCC
7420 RepID=B4VRZ4_9CYAN
Length = 539
Score = 143 bits (360), Expect = 1e-32
Identities = 80/184 (43%), Positives = 117/184 (63%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR+A + RL ELG+ L + +L+ F RFK VA++KK V+D DL ALV+DE+ Q +
Sbjct: 347 KHSGRNAFRSRLKELGFDLSETELNKAFVRFKEVADKKKDVSDWDLEALVNDEISQVPEL 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+ L +Q++CG T+TV L +G+E + ++GTGPVDA YKA++ +V P L+EY
Sbjct: 407 FHLELVQVSCGDHARPTATVTLRTPEGEELMDAAIGTGPVDAVYKAINRVVNVPNELIEY 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDA+ + +R Y+S R FSG A DI+V+S +AYV A
Sbjct: 467 SVQSVTAGIDALGEVTIRLR----YNS----------RVFSGHAANTDIIVASAQAYVNA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[62][TOP]
>UniRef100_Q0IBI3 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. CC9311
RepID=LEU1_SYNS3
Length = 540
Score = 142 bits (358), Expect = 2e-32
Identities = 77/184 (41%), Positives = 119/184 (64%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL ELGY L L + F RFK +A++K+ +TD DL ++VS +V QP+A
Sbjct: 347 KLSGRSAVRARLEELGYDLSREDLDDAFARFKDLADRKREITDRDLESIVSVQVQQPDAK 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG+ T+TV LAD +G+E A SVGTGPVDA ++++ + EP L+E+
Sbjct: 407 YQLKLVQVSCGSSLQPTATVTLADENGQEQTAASVGTGPVDAVCRSLNQLAGEPNELVEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VTEGIDA+ + +R D + +SG A D+VV++ +A+V A
Sbjct: 467 SVKSVTEGIDAMGDVTIRLRRDG--------------QLYSGHSAHTDVVVAAAEAFVNA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[63][TOP]
>UniRef100_Q7TUV5 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus str. MIT
9313 RepID=LEU1_PROMM
Length = 540
Score = 142 bits (358), Expect = 2e-32
Identities = 79/184 (42%), Positives = 117/184 (63%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL ELGY L L F RFK +A++K+ +TD DL A+VS++V Q EA
Sbjct: 347 KLSGRSAVRARLEELGYDLTREDLDEAFARFKDLADRKRDITDRDLEAIVSEQVQQSEAR 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG+ T+TV LA DG+E A +VGTGPVDA +A++ + EP L+E+
Sbjct: 407 FQLRLVQVSCGSSLRPTATVILAQEDGQEQTAAAVGTGPVDAVCRALNALAGEPNELIEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VTEGIDA+ + +R D + FSG A D+VV++ +A+V A
Sbjct: 467 SVKSVTEGIDAMGEVTIRLRRDG--------------QLFSGHSADTDVVVAAAQAFVNA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[64][TOP]
>UniRef100_B5W9X6 LeuA allosteric (Dimerisation) domain n=1 Tax=Arthrospira maxima
CS-328 RepID=B5W9X6_SPIMA
Length = 272
Score = 142 bits (357), Expect = 2e-32
Identities = 76/184 (41%), Positives = 113/184 (61%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA ++RL ELG+ L D +++ F RFK VA++KK VT+ D+ A+V+DE+ Q +
Sbjct: 83 KHSGRHAFQNRLQELGFDLSDDEINKAFVRFKDVADKKKEVTNWDIEAIVNDEIQQTPEL 142
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG T+TV L G+E + GTGPVDA YKA++ +V P L+E+
Sbjct: 143 FRLELVQVSCGNNARPTATVTLRTPQGQELTDAATGTGPVDAVYKAINRVVNVPNELIEF 202
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDAI + +R R FSG A DI+V+S +AY+ A
Sbjct: 203 SVQSVTAGIDAIGEVTIRLRYQG--------------RVFSGHAANTDIIVASAQAYINA 248
Query: 543 LNKM 554
LN++
Sbjct: 249 LNRL 252
[65][TOP]
>UniRef100_Q3AYY2 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. CC9902
RepID=LEU1_SYNS9
Length = 540
Score = 142 bits (357), Expect = 2e-32
Identities = 77/184 (41%), Positives = 114/184 (61%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL ELGY L L F RFK +A++K+ +TD DL A+VS++V QPEA
Sbjct: 347 KLSGRSAVRARLEELGYNLTREDLDEAFARFKDLADRKREITDRDLEAIVSEQVQQPEAR 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG+ T+TV L D +G E +VGTGPVDA +A++ + P L+E+
Sbjct: 407 FQLKFVQVSCGSTSRPTATVALMDEEGGERTVSAVGTGPVDAVCRALNCLADVPNDLIEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VTEGIDAI + +R D + +SG A D+VV++ A+V A
Sbjct: 467 SVKSVTEGIDAIGEVTIRLRRDGS--------------LYSGHAADTDVVVAAAMAFVNA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[66][TOP]
>UniRef100_A5GM47 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. WH 7803
RepID=LEU1_SYNPW
Length = 540
Score = 142 bits (357), Expect = 2e-32
Identities = 76/184 (41%), Positives = 118/184 (64%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL ELGY L L + F RFK +A++K+ +TD DL A+VS++V QP+A
Sbjct: 347 KLSGRSAVRARLEELGYDLSREDLDDAFARFKELADRKRDITDRDLEAIVSEQVQQPDAR 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG+ T+TV L D +G+E ++GTGPVDA +A++ + EP L+E+
Sbjct: 407 YQLKLVQVSCGSSLQPTATVTLLDEEGQEQSEAAIGTGPVDAVCRALNALAGEPNELVEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VTEGIDA+ + +R D + FSG A D+VV++ +A+V A
Sbjct: 467 SVKSVTEGIDAMGEVTIRLRRDG--------------QLFSGHAADTDVVVAAAQAFVNA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[67][TOP]
>UniRef100_Q3MBA3 2-isopropylmalate synthase n=1 Tax=Anabaena variabilis ATCC 29413
RepID=LEU1_ANAVT
Length = 531
Score = 142 bits (357), Expect = 2e-32
Identities = 75/184 (40%), Positives = 117/184 (63%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR+A + RL ELG+ L + +L+ F +FK VA++KK ++D DL A+V+DE+ Q +
Sbjct: 347 KHSGRNAFRTRLKELGFELSETELNKAFVKFKEVADKKKEISDWDLEAIVNDEIQQAPDL 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+++ +Q++CG+ T+TV L DG+E ++GTGPVDA YKA++ +V P L+E+
Sbjct: 407 FRVELVQVSCGSNARPTATVTLRTPDGEELTDAAIGTGPVDAVYKAINRVVNVPNQLIEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDAI + +R ++ R FSG A DI+V+S +AYV A
Sbjct: 467 SVQSVTAGIDAIGEVTIRLRYES--------------RVFSGHAANTDIIVASAQAYVNA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[68][TOP]
>UniRef100_P48575 2-isopropylmalate synthase n=1 Tax=Nostoc sp. PCC 7120
RepID=LEU1_ANASP
Length = 531
Score = 142 bits (357), Expect = 2e-32
Identities = 75/184 (40%), Positives = 117/184 (63%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR+A + RL ELG+ L + +L+ F +FK VA++KK ++D DL A+V+DE+ Q +
Sbjct: 347 KHSGRNAFRTRLKELGFELSETELNKAFVKFKEVADKKKEISDWDLEAIVNDEIQQAPDL 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+++ +Q++CG+ T+TV L DG+E ++GTGPVDA YKA++ +V P L+E+
Sbjct: 407 FRVELVQVSCGSNARPTATVTLRTPDGEELTDAAIGTGPVDAVYKAINRVVNVPNQLIEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDAI + +R ++ R FSG A DI+V+S +AYV A
Sbjct: 467 SVQSVTAGIDAIGEVTIRLRYES--------------RVFSGHAANTDIIVASAQAYVNA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[69][TOP]
>UniRef100_B4WG76 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. PCC 7335
RepID=B4WG76_9SYNE
Length = 560
Score = 141 bits (356), Expect = 3e-32
Identities = 77/184 (41%), Positives = 113/184 (61%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR+A + RL ELG+ L D +L+ F RFK +A++KK ++D DL A+V+DE Q
Sbjct: 368 KHSGRNAFRTRLKELGFDLGDQELNKAFLRFKDIADKKKEISDRDLEAIVNDETLQVAEH 427
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+K +Q++CG+ T+T+ + DG+E S+GTGPVDA Y+A++ IV P L+EY
Sbjct: 428 FKAELIQVSCGSNAQPTATITIRMPDGQELTDASIGTGPVDAIYRAINRIVDIPNDLIEY 487
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDA+ + +R D ER +SG A DIVV+S AY+ A
Sbjct: 488 SVQSVTAGIDAMGEVTIRLRHD--------------ERIYSGHAANTDIVVASAYAYINA 533
Query: 543 LNKM 554
LN++
Sbjct: 534 LNRL 537
[70][TOP]
>UniRef100_B9P2F2 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus str. MIT
9202 RepID=B9P2F2_PROMA
Length = 546
Score = 141 bits (355), Expect = 4e-32
Identities = 77/185 (41%), Positives = 117/185 (63%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL E+GY L L++ F RFK +A++K+ +TD DL A+VS++V PEA
Sbjct: 347 KLSGRSAVRARLEEMGYDLSREDLNDAFTRFKDLADRKREITDRDLEAIVSEQVQLPEAK 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADS-DGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++L +Q++CG T+T+ L ++ D E A S+GTGPVDA +A++ + K P L+E
Sbjct: 407 FQLSLVQVSCGNASKPTATISLINTEDDSEDTAVSIGTGPVDAVCEALNKLAKVPNELIE 466
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
+S+ +VTEGIDA+ + IR DN + +SG A D+VV++ AYV
Sbjct: 467 FSVKSVTEGIDALGEVTIRIRRDN--------------KIYSGHSADTDVVVAAANAYVN 512
Query: 540 ALNKM 554
ALN++
Sbjct: 513 ALNRL 517
[71][TOP]
>UniRef100_Q31AF9 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus str. MIT
9312 RepID=LEU1_PROM9
Length = 546
Score = 141 bits (355), Expect = 4e-32
Identities = 78/185 (42%), Positives = 117/185 (63%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL E+GY L L++ F RFK +A++K+ +TD DL A+VS++V PEA
Sbjct: 347 KLSGRSAVRARLEEMGYDLSREDLNDAFARFKDLADRKREITDRDLEAIVSEQVQLPEAK 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLAD-SDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++L +Q++CG T+T+ L + +D E A SVGTGPVDA +A++ + K P L+E
Sbjct: 407 FQLCLVQVSCGNASKPTATITLLNTADNTEDTAVSVGTGPVDAVCEALNKLAKVPNELIE 466
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
+S+ +VTEGIDA+ + IR DN + +SG A D+VV++ AYV
Sbjct: 467 FSVKSVTEGIDALGEVTIRIRRDN--------------KIYSGHSADTDVVVAAANAYVN 512
Query: 540 ALNKM 554
ALN++
Sbjct: 513 ALNRL 517
[72][TOP]
>UniRef100_A8G5D5 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus str. MIT
9215 RepID=LEU1_PROM2
Length = 546
Score = 141 bits (355), Expect = 4e-32
Identities = 77/185 (41%), Positives = 117/185 (63%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL E+GY L L++ F RFK +A++K+ +TD DL A+VS++V PEA
Sbjct: 347 KLSGRSAVRARLEEMGYDLSREDLNDAFARFKDLADRKREITDRDLEAIVSEQVQLPEAK 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADS-DGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++L +Q++CG T+T+ L ++ D E A S+GTGPVDA +A++ + K P L+E
Sbjct: 407 FQLSLVQVSCGNASKPTATISLINTEDNSEDTAVSIGTGPVDAVCEALNKLAKVPNELIE 466
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
+S+ +VTEGIDA+ + IR DN + +SG A D+VV++ AYV
Sbjct: 467 FSVKSVTEGIDALGEVTIRIRRDN--------------KIYSGHSADTDVVVAAANAYVN 512
Query: 540 ALNKM 554
ALN++
Sbjct: 513 ALNRL 517
[73][TOP]
>UniRef100_A2BRP4 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus str.
AS9601 RepID=LEU1_PROMS
Length = 546
Score = 140 bits (354), Expect = 5e-32
Identities = 77/185 (41%), Positives = 117/185 (63%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL E+GY L L++ F RFK +A++K+ +TD DL A+VS++V PEA
Sbjct: 347 KLSGRSAVRARLEEMGYDLSREDLNDAFARFKDLADRKREITDRDLEAIVSEQVQLPEAK 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADS-DGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++L +Q++CG T+T+ L ++ D E A S+GTGPVDA +A++ + K P L+E
Sbjct: 407 FQLSLVQVSCGNASKPTATISLLNTEDNTEDTAVSIGTGPVDAVCEALNKLAKVPNELIE 466
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
+S+ +VTEGIDA+ + IR DN + +SG A D+VV++ AYV
Sbjct: 467 FSVKSVTEGIDALGEVTIRIRRDN--------------KIYSGHSADTDVVVAAANAYVN 512
Query: 540 ALNKM 554
ALN++
Sbjct: 513 ALNRL 517
[74][TOP]
>UniRef100_Q065B6 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. BL107
RepID=Q065B6_9SYNE
Length = 540
Score = 140 bits (353), Expect = 6e-32
Identities = 77/184 (41%), Positives = 114/184 (61%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL ELGY L L F RFK +A++K+ +TD DL A+VS++V QPEA
Sbjct: 347 KLSGRSAVRARLEELGYNLTRDDLDEAFARFKDLADRKREITDRDLEAIVSEQVQQPEAR 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG+ T+TV L D +G E +VGTGPVDA +A++ + P L+E+
Sbjct: 407 FQLKFVQVSCGSSSRPTATVTLIDEEGGESTGSAVGTGPVDAVCRALNGLADVPNDLIEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VTEGIDAI + +R D + +SG A D+VV++ A+V A
Sbjct: 467 SVKSVTEGIDAIGEVTIRLRRDGS--------------LYSGHAADTDVVVAAAMAFVNA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[75][TOP]
>UniRef100_A3PDH0 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus str. MIT
9301 RepID=LEU1_PROM0
Length = 546
Score = 140 bits (353), Expect = 6e-32
Identities = 76/185 (41%), Positives = 117/185 (63%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL E+GY L L++ F RFK +A++K+ +TD DL A+VS++V PEA
Sbjct: 347 KLSGRSAVRARLEEMGYDLSREDLNDAFARFKDLADRKREITDRDLEAIVSEQVQLPEAK 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADS-DGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++L +Q++CG T+T+ L ++ D E A S+GTGPVDA +A++ + K P L+E
Sbjct: 407 FQLSLVQVSCGNASKPTATISLLNTEDNTEDTAVSIGTGPVDAVCEALNKLAKVPNELIE 466
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
+S+ +VTEGIDA+ + IR DN + +SG A D+VV++ AY+
Sbjct: 467 FSVKSVTEGIDALGEVTIRIRRDN--------------KIYSGHSADTDVVVAAANAYIN 512
Query: 540 ALNKM 554
ALN++
Sbjct: 513 ALNRL 517
[76][TOP]
>UniRef100_B2IU89 2-isopropylmalate synthase n=1 Tax=Nostoc punctiforme PCC 73102
RepID=B2IU89_NOSP7
Length = 534
Score = 140 bits (352), Expect = 8e-32
Identities = 75/184 (40%), Positives = 116/184 (63%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR+A + RL ELG+ L D +L+ F RFK VA++KK ++D DL A+V+DE+ Q +
Sbjct: 347 KHSGRNAFRTRLKELGFELSDTELNKAFVRFKEVADKKKDISDWDLEAIVNDEIQQAPDL 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+++ +Q++CG+ T+TV L G+E ++GTGPVDA YKA++ +V P L+E+
Sbjct: 407 FRVELVQVSCGSNARPTATVTLRTPKGEELTDAAIGTGPVDAVYKAINRVVNVPNELIEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDAI + +R ++ + FSG A DI+V+S +AYV A
Sbjct: 467 SVQSVTAGIDAIGEVTIRLRYES--------------KVFSGHAANTDIIVASAQAYVNA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[77][TOP]
>UniRef100_A0YYJ6 2-isopropylmalate synthase n=1 Tax=Lyngbya sp. PCC 8106
RepID=A0YYJ6_9CYAN
Length = 536
Score = 140 bits (352), Expect = 8e-32
Identities = 73/184 (39%), Positives = 114/184 (61%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA ++RL ELG+ L D ++ F +FK +A++KK +TD DL ++ ++E+ Q +
Sbjct: 349 KHSGRHAFQNRLQELGFELSDSDINKAFIKFKDLADKKKEITDWDLESIANNEIHQAPEL 408
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG T+TV L G+E + ++GTGPVDA YKA++ +V P L+E+
Sbjct: 409 FRLELVQVSCGDHARPTATVILRTPTGEELMDAAIGTGPVDAVYKAINRVVNIPNELIEF 468
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDAI + +R + R FSG A DI+V+S +AYV A
Sbjct: 469 SVQSVTAGIDAIGEVTIRLRAEG--------------RVFSGHAANTDIIVASAQAYVNA 514
Query: 543 LNKM 554
LN++
Sbjct: 515 LNRL 518
[78][TOP]
>UniRef100_B8G7X2 2-isopropylmalate synthase n=1 Tax=Chloroflexus aggregans DSM 9485
RepID=B8G7X2_CHLAD
Length = 568
Score = 139 bits (351), Expect = 1e-31
Identities = 74/192 (38%), Positives = 119/192 (61%), Gaps = 8/192 (4%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA + L E GY L+D + ++F RFK + ++KK+V D D+ AL++ E+ +
Sbjct: 340 KHSGRHAFRKYLEEKGYKLNDDEFQHVFARFKDLCDRKKKVDDRDIEALIAGEMQHTPEL 399
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL +Q G + T+TV+L DG+ V + GTGPVDA Y+A++ I++ P L+E+
Sbjct: 400 YKLDHVQYASGVGMIPTATVRLIGPDGQAKVDSAQGTGPVDAVYQAINRIIQRPNELIEF 459
Query: 363 SMNAVTEGIDAIATTRVLIR--------GDNNYSSTNAVTGESVERTFSGTGAGMDIVVS 518
S+NA+TEG+DA+A V IR +++ ++T+ ++ FSG G D +V+
Sbjct: 460 SINAITEGLDAVAEVTVRIREQGSSARLSESSSTATSLTGRRQSQQIFSGYGVHTDTIVA 519
Query: 519 SVKAYVGALNKM 554
+ +AY+ ALNKM
Sbjct: 520 AAQAYMAALNKM 531
[79][TOP]
>UniRef100_B0JGK2 2-isopropylmalate synthase n=1 Tax=Microcystis aeruginosa NIES-843
RepID=LEU1_MICAN
Length = 533
Score = 139 bits (351), Expect = 1e-31
Identities = 75/184 (40%), Positives = 113/184 (61%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR+A + RL ELG+ L + +L+N F +FK +A++KK +TD DL A+V+DE+
Sbjct: 348 KLSGRNAFRSRLQELGFELSETELNNAFIQFKEMADRKKEITDRDLEAIVNDEIDTVPDH 407
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG T+TV + DG E ++GTGPVDA KA+D +VK P L+ +
Sbjct: 408 FRLELVQVSCGNSARPTATVTIRTPDGSELSDAAIGTGPVDALCKAIDRVVKIPNELISF 467
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ VTEGIDA+ + +R + RT+S A DI+V+S +AYV A
Sbjct: 468 SVREVTEGIDALGEVTIRLRYEG--------------RTYSAHAADTDIIVASARAYVSA 513
Query: 543 LNKM 554
LN++
Sbjct: 514 LNRL 517
[80][TOP]
>UniRef100_Q5N5T3 2-isopropylmalate synthase n=1 Tax=Synechococcus elongatus PCC 6301
RepID=Q5N5T3_SYNP6
Length = 540
Score = 139 bits (350), Expect = 1e-31
Identities = 76/184 (41%), Positives = 114/184 (61%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR+A + RL ELGY L + L+ F RFK +A++K+ VTD DL A+V+DE Q +
Sbjct: 349 KLSGRNAFRTRLQELGYDLGEDDLNRAFLRFKELADKKREVTDRDLEAIVNDETQQAPEL 408
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL +Q++ G T+TV L +G+E ++GTGPVDA Y+A++ +V P L+E+
Sbjct: 409 FKLELVQVSAGDHARPTATVTLRTPEGEELTDAAIGTGPVDAIYRAINRVVNIPNELIEF 468
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDAI + +R + +R FSG A DI+V+S +AY+ A
Sbjct: 469 SVKSVTAGIDAIGEVTIRLRHE--------------DRIFSGHSANTDILVASAQAYIHA 514
Query: 543 LNKM 554
LN++
Sbjct: 515 LNRL 518
[81][TOP]
>UniRef100_Q31NC9 2-isopropylmalate synthase n=1 Tax=Synechococcus elongatus PCC 7942
RepID=Q31NC9_SYNE7
Length = 540
Score = 139 bits (350), Expect = 1e-31
Identities = 76/184 (41%), Positives = 114/184 (61%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR+A + RL ELGY L + L+ F RFK +A++K+ VTD DL A+V+DE Q +
Sbjct: 349 KLSGRNAFRTRLQELGYDLGEDDLNRAFLRFKELADKKREVTDRDLEAIVNDETQQAPEL 408
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL +Q++ G T+TV L +G+E ++GTGPVDA Y+A++ +V P L+E+
Sbjct: 409 FKLELVQVSAGDHARPTATVTLRTPEGEELTDAAIGTGPVDAIYRAINRVVNIPNELIEF 468
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDAI + +R + +R FSG A DI+V+S +AY+ A
Sbjct: 469 SVKSVTAGIDAIGEVTIRLRHE--------------DRIFSGHSANTDILVASAQAYIHA 514
Query: 543 LNKM 554
LN++
Sbjct: 515 LNRL 518
[82][TOP]
>UniRef100_A8YBI6 LeuA protein n=1 Tax=Microcystis aeruginosa PCC 7806
RepID=A8YBI6_MICAE
Length = 533
Score = 139 bits (350), Expect = 1e-31
Identities = 75/184 (40%), Positives = 112/184 (60%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR+A + RL ELG+ L + +L+N F +FK +A++KK +TD DL A+V+DE+
Sbjct: 348 KLSGRNAFRSRLQELGFELSETELNNAFIQFKEMADRKKEITDRDLEAIVNDEIDTVPDH 407
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q+ CG T+TV + DG E ++GTGPVDA KA+D +VK P L+ +
Sbjct: 408 FRLELVQVACGNNARPTATVTIRTPDGSELSDAAIGTGPVDALCKAIDRVVKIPNELISF 467
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ VTEGIDA+ + +R + RT+S A DI+V+S +AYV A
Sbjct: 468 SVREVTEGIDALGEVTIRLRYEG--------------RTYSARAADTDIIVASARAYVSA 513
Query: 543 LNKM 554
LN++
Sbjct: 514 LNRL 517
[83][TOP]
>UniRef100_Q112U2 2-isopropylmalate synthase n=1 Tax=Trichodesmium erythraeum IMS101
RepID=LEU1_TRIEI
Length = 541
Score = 139 bits (350), Expect = 1e-31
Identities = 72/184 (39%), Positives = 115/184 (62%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHA + RL ELG+ L D +++ F +FK +A++KK +TD DL ++V+ E+ QP +
Sbjct: 347 KLSGRHAFQSRLQELGFKLSDEEINKAFIKFKDLADKKKEITDWDLESIVNAEIQQPPEL 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG T+TV + +G+E ++GTGPVDA YKA++ +V L+E+
Sbjct: 407 FRLELVQVSCGDRSRPTATVIIRTPNGEELTDAAIGTGPVDAVYKAINRVVNVENDLVEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDAI + +R + R +SG A DI+V+S +AY+ A
Sbjct: 467 SVQSVTAGIDAIGEVTIRVRHEG--------------RVYSGHAANTDIIVASAEAYLSA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[84][TOP]
>UniRef100_A5GRZ0 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. RCC307
RepID=LEU1_SYNR3
Length = 537
Score = 138 bits (348), Expect = 2e-31
Identities = 76/184 (41%), Positives = 116/184 (63%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL ELGY LD L++ F RFK +A++K+ +TD DL A+V Q EA
Sbjct: 347 KLSGRSAVRARLEELGYQLDGDDLNDAFARFKELADRKREITDRDLEAIVRQNAQQIEAY 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG +T+TV L SDG+E ++GTGPVDA +A++ +V+ P L+E+
Sbjct: 407 YQLAGVQVSCGRDLRATATVTLRTSDGEECSQAAIGTGPVDAVCQALNGLVQVPNELVEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VTEGIDA+ + +R D R +SG A D+VV++ +A+V A
Sbjct: 467 SVKSVTEGIDAMGEVTIRLRQDG--------------RLYSGHAADTDVVVAAAQAFVNA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[85][TOP]
>UniRef100_A9WC27 2-isopropylmalate synthase n=2 Tax=Chloroflexus RepID=A9WC27_CHLAA
Length = 568
Score = 138 bits (347), Expect = 3e-31
Identities = 77/192 (40%), Positives = 120/192 (62%), Gaps = 8/192 (4%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA + L E GY L++ + ++F RFK + ++KK+V D D+ AL++ E+ +
Sbjct: 340 KHSGRHAFRKYLEEKGYKLNEEEFQHVFARFKDLCDRKKKVDDRDIEALIAGEMQHTPEL 399
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL +Q G + T+TV+L DG+ + + GTGPVDA Y+A++ I++ P L+E+
Sbjct: 400 YKLDHVQYASGIGMIPTATVRLIGPDGQTRIDSAQGTGPVDAVYQAINRIIQRPNELIEF 459
Query: 363 SMNAVTEGIDAIATTRVLIRGD------NNYSST-NAVTG-ESVERTFSGTGAGMDIVVS 518
S+NA+TEG+DA+A V IR N SST ++TG ++ FSG G D +V+
Sbjct: 460 SINAITEGLDAVAEVTVRIREQGAPARLNESSSTATSLTGRRPAQQIFSGYGVHTDTIVA 519
Query: 519 SVKAYVGALNKM 554
+ +AY+ ALNKM
Sbjct: 520 AAQAYMAALNKM 531
[86][TOP]
>UniRef100_Q7U892 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. WH 8102
RepID=LEU1_SYNPX
Length = 540
Score = 137 bits (345), Expect = 5e-31
Identities = 74/184 (40%), Positives = 115/184 (62%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL ELGY L L F RFK +A++K+ +TD DL A+VS++V QPEA
Sbjct: 347 KLSGRSAVRARLEELGYDLTREDLDEAFARFKDLADRKREITDRDLEAIVSEQVQQPEAR 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CGT T+TV L++ +G + +VGTGPVDA +A++ + P L+E+
Sbjct: 407 YQLQLVQVSCGTRLKPTATVALSEENGPDQTVSAVGTGPVDAVCRALNQLAGVPNELIEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VTEGIDA+ + +R D + +SG A D+VV++ A++ A
Sbjct: 467 SVKSVTEGIDAMGEVTIRLRRDGS--------------LYSGHAADTDVVVAAAMAFINA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[87][TOP]
>UniRef100_P94907 2-isopropylmalate synthase n=1 Tax=Microcystis aeruginosa
RepID=LEU1_MICAE
Length = 533
Score = 137 bits (345), Expect = 5e-31
Identities = 75/184 (40%), Positives = 114/184 (61%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR+A + RL ELG+ L + +L+N F +FK +A++KK +TD DL A+V+DE+
Sbjct: 348 KLSGRNAFRSRLQELGFELSETELNNAFIQFKEMADRKKEITDRDLEAIVNDEIDTVPDH 407
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG T+TV + DG E ++GTGPVDA KA+D +V+ P L+ +
Sbjct: 408 FRLELVQVSCGNNARPTATVTIRTPDGSELSDAAIGTGPVDALCKAIDRVVQIPNELISF 467
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ VTEGIDA+ + +R Y+ RT+S A DI+V+S +AYV A
Sbjct: 468 SVREVTEGIDALGEVTIRLR----YAG----------RTYSARAADTDIIVASARAYVSA 513
Query: 543 LNKM 554
LN++
Sbjct: 514 LNRL 517
[88][TOP]
>UniRef100_Q7V121 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus subsp.
pastoris str. CCMP1986 RepID=LEU1_PROMP
Length = 546
Score = 136 bits (343), Expect = 9e-31
Identities = 74/185 (40%), Positives = 117/185 (63%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL E+GY L L++ F RFK +A++K+ +TD DL A+VS++V PE+
Sbjct: 347 KLSGRSAVRARLEEMGYDLSREDLNDAFARFKELADRKREITDRDLEAIVSEQVQLPESK 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADS-DGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++L +Q++CG+ T+TV L ++ D E A ++GTGPVDA +A++ + K P L+E
Sbjct: 407 FQLSHVQVSCGSTSKPTATVTLINTEDHTEDTAVAIGTGPVDAVCEALNALTKVPNELIE 466
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
+S+ +VTEGIDA+ + IR N + +SG A D+VV++ A+V
Sbjct: 467 FSVKSVTEGIDALGEVTIRIRNKN--------------KIYSGHSADTDVVVAAANAFVN 512
Query: 540 ALNKM 554
ALN++
Sbjct: 513 ALNRL 517
[89][TOP]
>UniRef100_D0CH66 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. WH 8109
RepID=D0CH66_9SYNE
Length = 540
Score = 135 bits (340), Expect = 2e-30
Identities = 75/184 (40%), Positives = 114/184 (61%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL ELGY L L F RFK +A++K+ +TD DL A+VS++V QPEA
Sbjct: 347 KLSGRSAVRARLEELGYDLTREDLDEAFARFKELADRKREITDRDLEAIVSEQVQQPEAR 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG+ T+TV L+D +G E +VGTGPVDA +A++ + P L+E+
Sbjct: 407 FQLKLVQVSCGSSLRPTATVTLSDEEGSETTGSAVGTGPVDAVCRALNDLAGVPNELIEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VTEGIDA+ + +R + +SG A D+VV++ A+V A
Sbjct: 467 SVKSVTEGIDAMGDVTIRLRRNG--------------ALYSGHAADTDVVVAAAMAFVNA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[90][TOP]
>UniRef100_A5G7V0 2-isopropylmalate synthase n=1 Tax=Geobacter uraniireducens Rf4
RepID=A5G7V0_GEOUR
Length = 516
Score = 134 bits (336), Expect = 6e-30
Identities = 78/184 (42%), Positives = 111/184 (60%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA K RL ELGY LDD +L+ F RFKA+A+ KK V D DL A+V+DEV E
Sbjct: 337 KHSGRHAFKKRLEELGYDLDDEKLNRAFDRFKALADLKKEVFDEDLDAIVADEVLTAEEK 396
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL + +TCG+ ++T+TV++ + DG + +G GPVDA KA+ + K A LL+Y
Sbjct: 397 YKLSHITVTCGSFAVATATVQM-EIDGIQVRTAELGDGPVDATLKAIKKLTKTKAKLLQY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++ ++T G DA +G+ T+ RT G GA DI+ +S KAY+ A
Sbjct: 456 NVGSITGGTDA--------QGEVTVRLTDGA------RTVIGRGASTDIIEASAKAYIHA 501
Query: 543 LNKM 554
LN++
Sbjct: 502 LNRL 505
[91][TOP]
>UniRef100_B9YKB8 2-isopropylmalate synthase n=1 Tax='Nostoc azollae' 0708
RepID=B9YKB8_ANAAZ
Length = 530
Score = 133 bits (335), Expect = 8e-30
Identities = 73/184 (39%), Positives = 114/184 (61%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR+A + RL EL + L D L+ F RFK VA++KK ++D DL A+V+DE+ Q +
Sbjct: 347 KHSGRNAFRTRLRELSFELSDKDLNKAFIRFKEVADKKKEISDWDLEAIVNDEIQQAPDL 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+++ +Q++CG+ T+TV L +G+E ++GTGP+DA YKA++ +V P L+E+
Sbjct: 407 FRVELVQVSCGSNTQPTATVTLRTPNGEELTDAAIGTGPIDAVYKAINRVVNVPNELIEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDA+ + + +Y S FSG A DI+V+S +AYV A
Sbjct: 467 SVQSVTGGIDALGEVTIRL----SYESC----------VFSGHAANTDIIVASAQAYVNA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[92][TOP]
>UniRef100_Q3AIA2 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. CC9605
RepID=LEU1_SYNSC
Length = 540
Score = 133 bits (335), Expect = 8e-30
Identities = 75/184 (40%), Positives = 113/184 (61%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL ELGY L L F RFK +A++K+ +TD DL A+VS++V QPEA
Sbjct: 347 KLSGRSAVRARLEELGYDLTREDLDEAFARFKELADRKREITDRDLEAIVSEQVQQPEAR 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q++CG+ T+TV L D +G E +VGTGPVDA +A++ + P L+E+
Sbjct: 407 FQLKLVQVSCGSSLRPTATVTLLDEEGSETTGSAVGTGPVDAVCRALNDLAGVPNELIEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VTEGIDA+ + +R + +SG A D+VV++ A+V A
Sbjct: 467 SVKSVTEGIDAMGDVTIRLRRNG--------------ALYSGHAADTDVVVAAGMAFVNA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[93][TOP]
>UniRef100_B9M5A8 2-isopropylmalate synthase n=1 Tax=Geobacter sp. FRC-32
RepID=B9M5A8_GEOSF
Length = 516
Score = 132 bits (332), Expect = 2e-29
Identities = 76/184 (41%), Positives = 109/184 (59%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA K RL ELGY LDD +L+ F RFKA+A+ KK V D DL ALV+DE+ + V
Sbjct: 337 KHSGRHAFKKRLEELGYDLDDEKLNQAFERFKALADLKKEVFDEDLDALVADEIMRAHEV 396
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL + +TCG+ ++T+TV++ + +G +G GPVDA KA+ + K A L +Y
Sbjct: 397 YKLSHITVTCGSFAVATATVQM-EIEGNPVRTAELGDGPVDATLKAIKKLTKTKAKLQQY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++ ++T G DA +G+ N RT G G+ DI+ +S KAY+ A
Sbjct: 456 NVGSITGGTDA--------QGEVNVRLAEG------SRTVIGKGSSTDIIEASAKAYIDA 501
Query: 543 LNKM 554
LNK+
Sbjct: 502 LNKL 505
[94][TOP]
>UniRef100_B2J7L4 2-isopropylmalate synthase n=1 Tax=Nostoc punctiforme PCC 73102
RepID=B2J7L4_NOSP7
Length = 540
Score = 132 bits (331), Expect = 2e-29
Identities = 74/185 (40%), Positives = 113/185 (61%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEV-FQPEA 179
K SGR+A + RL ELG+ L++ L+ F RFK VA++KK ++D DL A+V DE Q E+
Sbjct: 349 KHSGRNAFRTRLKELGFELNEADLNKAFNRFKDVADKKKEISDWDLEAIVRDETQIQVES 408
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
+++ +Q+ CG T+T+ + DGK SVGTGPVDA Y+A++ +V+ P L+E
Sbjct: 409 GFQIEHVQVICGDCTCPTATITIVTPDGKILTDASVGTGPVDAVYQAINRLVQIPNQLIE 468
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
+S+ +VT GIDA+ T V ++ ER FSG + DIVV++ A++
Sbjct: 469 FSVQSVTGGIDALGTVTVRLKHQ--------------ERIFSGQASDTDIVVAAAYAHIN 514
Query: 540 ALNKM 554
ALN++
Sbjct: 515 ALNRL 519
[95][TOP]
>UniRef100_A5UUP9 2-isopropylmalate synthase n=1 Tax=Roseiflexus sp. RS-1
RepID=A5UUP9_ROSS1
Length = 556
Score = 132 bits (331), Expect = 2e-29
Identities = 75/187 (40%), Positives = 110/187 (58%), Gaps = 3/187 (1%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLD-DGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEA 179
K SGR+AL+ +L +GY D + + + +F RFK + ++KK V D DL L +
Sbjct: 333 KHSGRNALRTKLAAMGYEFDSEEEFNQVFQRFKELCDKKKVVDDRDLEVLATGGSLHTPD 392
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
+++L +Q+TCGT +TV++ D DG H + GTGPVDA YKA+D IV P L+E
Sbjct: 393 LYRLDHVQVTCGTGVTPVATVRITDPDGNTHTTAAHGTGPVDAIYKAIDKIVGRPNELIE 452
Query: 360 YSMNAVTEGIDAIATTRVLIR--GDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAY 533
+S+ AVTEGIDA+A V IR G+ V + +SG A D +V++ ++Y
Sbjct: 453 FSIKAVTEGIDAVAEVSVRIREPGNEVQEGEYRVGRHRGPQIYSGYSANTDTIVAAAESY 512
Query: 534 VGALNKM 554
+ ALNKM
Sbjct: 513 MTALNKM 519
[96][TOP]
>UniRef100_C7MNU3 2-isopropylmalate synthase n=1 Tax=Cryptobacterium curtum DSM 15641
RepID=C7MNU3_CRYCD
Length = 513
Score = 131 bits (329), Expect = 4e-29
Identities = 77/182 (42%), Positives = 104/182 (57%)
Frame = +3
Query: 9 SGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWK 188
SG ALK RL LGY D L L+ RF VA++KK V D DL +LV+D+ +A++
Sbjct: 333 SGHAALKHRLEHLGYTFDPPALDALYERFLEVADRKKEVYDEDLESLVADQARVTDAIYT 392
Query: 189 LLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSM 368
L +Q++CG T+T+ L D G C+ GTGP+DAA+KAVD I+ L E+S+
Sbjct: 393 LEAVQVSCGFPLTPTATLTLRDDQGATQTVCAFGTGPIDAAFKAVDEIMNVQGELQEFSV 452
Query: 369 NAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGALN 548
NAVT GIDA+ V +R G+ F G + DI+VSS KAY+ ALN
Sbjct: 453 NAVTHGIDALGEVTVRVR---------CAEGD----VFIGRASDGDIIVSSTKAYLHALN 499
Query: 549 KM 554
+M
Sbjct: 500 RM 501
[97][TOP]
>UniRef100_A2BX52 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus str. MIT
9515 RepID=LEU1_PROM5
Length = 546
Score = 131 bits (329), Expect = 4e-29
Identities = 70/185 (37%), Positives = 117/185 (63%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL E+GY L L++ F RFK +A++K+ +TD DL A+VS++V PE+
Sbjct: 347 KLSGRSAVRARLEEMGYDLSREDLNDAFARFKDLADRKREITDRDLEAIVSEQVQLPESR 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSD-GKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++L +Q++CG+ T+TV + +++ E + ++GTGPVDA +A++ + K P L+E
Sbjct: 407 FQLSHVQVSCGSTSKPTATVTILNTETHTEDTSVAIGTGPVDAVCEAINELAKVPNELIE 466
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
+S+ +VTEGIDA+ + IR N + +SG A D+VV++ A++
Sbjct: 467 FSVKSVTEGIDALGEVTIRIRNKN--------------KIYSGHSADTDVVVAAANAFLN 512
Query: 540 ALNKM 554
ALN++
Sbjct: 513 ALNRL 517
[98][TOP]
>UniRef100_Q74BX2 2-isopropylmalate synthase n=1 Tax=Geobacter sulfurreducens
RepID=Q74BX2_GEOSL
Length = 512
Score = 130 bits (328), Expect = 5e-29
Identities = 75/185 (40%), Positives = 107/185 (57%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA K RL ELGY L D L+ F RFKA+A+ KK V D DL A+V+DEV +P
Sbjct: 333 KHSGRHAFKKRLTELGYELSDEDLNKAFERFKALADMKKEVFDEDLDAIVADEVMRPSEK 392
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L + +TCG+ ++T+TV++ + DG +G GPVDA KA+ + K A L +Y
Sbjct: 393 YRLAHITVTCGSFAVATATVQM-EIDGVAVRTAELGDGPVDATLKAIKKLTKTKARLQQY 451
Query: 363 SMNAVTEGIDAIATTRV-LIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
++ ++T G DA V L+ GD T G G+ DI+ +S KAY+
Sbjct: 452 NVGSITGGTDAQGEVTVRLVDGD---------------ETVVGRGSSTDIIEASAKAYIN 496
Query: 540 ALNKM 554
ALN++
Sbjct: 497 ALNRL 501
[99][TOP]
>UniRef100_B8HST9 2-isopropylmalate synthase n=1 Tax=Cyanothece sp. PCC 7425
RepID=B8HST9_CYAP4
Length = 541
Score = 130 bits (328), Expect = 5e-29
Identities = 71/185 (38%), Positives = 112/185 (60%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR+A + RL ELG+ L + L+ F RFK +A++KK ++D DL A+V DE +
Sbjct: 350 KHSGRNAFRTRLRELGFELSETDLNKAFVRFKDLADKKKEISDWDLEAIVKDETQSQDVT 409
Query: 183 WKLLDM-QITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
L++ Q++CG T+TV + +G+E ++GTGPVDA Y+A++ +V P L+E
Sbjct: 410 GFGLELVQVSCGDHARPTATVTIRTPEGEELTDAAIGTGPVDAVYRAINRVVNVPNQLIE 469
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
+S+ +VTEGIDAI + +R + +R +SG A DI+V+S +AY+
Sbjct: 470 FSVQSVTEGIDAIGEVTIRLRHE--------------DRIYSGHAANTDIIVASAQAYLN 515
Query: 540 ALNKM 554
ALN++
Sbjct: 516 ALNRL 520
[100][TOP]
>UniRef100_A7NJH6 2-isopropylmalate synthase n=1 Tax=Roseiflexus castenholzii DSM
13941 RepID=A7NJH6_ROSCS
Length = 556
Score = 130 bits (328), Expect = 5e-29
Identities = 75/187 (40%), Positives = 109/187 (58%), Gaps = 3/187 (1%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLD-DGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEA 179
K SGR+AL+ +L +GY D + + + +F RFK + ++KK V D DL L +
Sbjct: 333 KHSGRNALRTKLAAMGYEFDSEEEFNQVFQRFKELCDKKKVVDDRDLEVLATGGSLHTPE 392
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
+++L +Q+TCGT +TV++ D DG + GTGPVDA YKA+D IV P L+E
Sbjct: 393 LYRLEHVQVTCGTGVTPVATVRITDPDGNTQTTAAHGTGPVDAIYKAIDKIVGRPNDLIE 452
Query: 360 YSMNAVTEGIDAIATTRVLIR--GDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAY 533
+S+ AVTEGIDA+A V IR GD V + +SG A D +V++ ++Y
Sbjct: 453 FSIKAVTEGIDAVAEVSVRIREPGDAVEEREYRVGRHRGPQIYSGYSANTDTIVAAAESY 512
Query: 534 VGALNKM 554
+ ALNKM
Sbjct: 513 MAALNKM 519
[101][TOP]
>UniRef100_A8CP47 2-isopropylmalate synthase n=1 Tax=Dehalococcoides sp. VS
RepID=A8CP47_9CHLR
Length = 505
Score = 130 bits (328), Expect = 5e-29
Identities = 72/184 (39%), Positives = 109/184 (59%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHA K L ELG+ L++ F FK +A++KK VTD D+ ALV++E+ +
Sbjct: 329 KLSGRHAFKQHLTELGFDLNEEDFDRAFKAFKDLADKKKDVTDRDIEALVAEELRTTVEL 388
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+ L +Q+T G G+ T+ V+L +G+ ++G+GPVDA YKA++ IV P L E+
Sbjct: 389 YHLDRIQVTSGDRGIPTAAVRLTTPNGEAAEDAALGSGPVDAVYKAINRIVNVPNKLTEF 448
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDA+ + I D T++G G+ DI+V+S KAY+ A
Sbjct: 449 SVKSVTAGIDALGEVLIRIESDG--------------VTYTGRGSDTDIIVASAKAYMNA 494
Query: 543 LNKM 554
LN++
Sbjct: 495 LNRL 498
[102][TOP]
>UniRef100_Q39W73 2-isopropylmalate synthase n=1 Tax=Geobacter metallireducens GS-15
RepID=Q39W73_GEOMG
Length = 512
Score = 130 bits (327), Expect = 7e-29
Identities = 75/184 (40%), Positives = 105/184 (57%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA K RL ELGY L D L+ F RFKA+A+ KK V D DL ALV+DEV +P
Sbjct: 333 KHSGRHAFKKRLAELGYELSDEDLNRAFERFKALADLKKEVFDEDLDALVADEVMRPAEK 392
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L + +TCG+ ++TSTV++ + DG +G GPVDA KA+ + K A L +Y
Sbjct: 393 FRLSHITVTCGSFAVATSTVQM-EIDGTAVRTAELGDGPVDATLKAIKKLTKTKAKLQQY 451
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++ ++T G DA V + N T G G+ DI+ +S KAY+ A
Sbjct: 452 NVGSITGGTDAQGEVTVRVTDGN--------------ETVVGRGSSTDIIEASAKAYINA 497
Query: 543 LNKM 554
LN++
Sbjct: 498 LNRL 501
[103][TOP]
>UniRef100_A5FR43 2-isopropylmalate synthase n=2 Tax=Dehalococcoides
RepID=A5FR43_DEHSB
Length = 505
Score = 130 bits (327), Expect = 7e-29
Identities = 73/184 (39%), Positives = 108/184 (58%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHA K L ELG+ L++ F FK +A++KK VTD D+ ALV++E+ +
Sbjct: 329 KLSGRHAFKQHLTELGFDLNEEDFDRAFKAFKDLADKKKDVTDRDIEALVAEELRTTVEL 388
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+ L +Q+T G G+ T+ V+L +G S+G+GPVDA YKA++ IV P L E+
Sbjct: 389 YHLDRIQVTSGDRGIPTAAVRLTTPNGGAVEDASLGSGPVDAVYKAINRIVNVPNKLTEF 448
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDA+ + I D T++G G+ DI+V+S KAY+ A
Sbjct: 449 SVKSVTAGIDALGEVLIRIESDG--------------VTYTGRGSDTDIIVASAKAYMNA 494
Query: 543 LNKM 554
LN++
Sbjct: 495 LNRL 498
[104][TOP]
>UniRef100_B5EHU7 2-isopropylmalate synthase n=1 Tax=Geobacter bemidjiensis Bem
RepID=B5EHU7_GEOBB
Length = 515
Score = 130 bits (326), Expect = 9e-29
Identities = 76/184 (41%), Positives = 105/184 (57%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA K RL ELG+ LDD L+ F RFKA+A+ KK V D DL A+V DE E
Sbjct: 335 KHSGRHAFKKRLEELGHELDDEALNKAFTRFKALADLKKEVFDEDLDAIVLDEAKNIEEK 394
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL + +TCG+ ++T+TV++ + DG + A +G GPVDA KA+ + K LL+Y
Sbjct: 395 YKLSHITVTCGSFAVATATVQM-EIDGMQVRAAELGDGPVDATMKAIKKLTKRDVKLLQY 453
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++ A+T G DAI V I E G G+ DI+ +S KAY+ A
Sbjct: 454 NVGAITGGTDAIGEVTVRIT-------------EEDRTPVVGRGSSTDIIEASAKAYIDA 500
Query: 543 LNKM 554
LN++
Sbjct: 501 LNRL 504
[105][TOP]
>UniRef100_Q3Z892 2-isopropylmalate synthase n=1 Tax=Dehalococcoides ethenogenes 195
RepID=Q3Z892_DEHE1
Length = 505
Score = 129 bits (325), Expect = 1e-28
Identities = 72/184 (39%), Positives = 108/184 (58%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHA K L ELG+ L++ F FK +A++KK VTD D+ ALV++E+ +
Sbjct: 329 KLSGRHAFKQHLTELGFDLNEEDFDRAFKAFKDLADKKKDVTDRDIEALVAEELRTTVEL 388
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+ L +Q+T G G+ T+ V+L +G ++G+GPVDA YKA++ IV P L E+
Sbjct: 389 YHLDRIQVTSGDRGIPTAAVRLTTPNGGAAEDAALGSGPVDAVYKAINRIVNVPNKLTEF 448
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GIDA+ + I D T++G G+ DI+V+S KAY+ A
Sbjct: 449 SVKSVTAGIDALGEVLIRIESDG--------------VTYTGRGSDTDIIVASAKAYMNA 494
Query: 543 LNKM 554
LN++
Sbjct: 495 LNRL 498
[106][TOP]
>UniRef100_A6TTR8 2-isopropylmalate synthase n=1 Tax=Alkaliphilus metalliredigens
QYMF RepID=A6TTR8_ALKMQ
Length = 513
Score = 129 bits (325), Expect = 1e-28
Identities = 75/184 (40%), Positives = 109/184 (59%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SG HAL+DRL ELGY + +L+ +F FK +A++KK + D DL ALV D+ E +
Sbjct: 332 KHSGSHALEDRLKELGYEISKEKLNEVFKEFKILADRKKVIYDRDLEALVQDQKQNFEEI 391
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L + I CG + ST+ +KL DGKE + G GP+DAA+KA+D IV L +Y
Sbjct: 392 YQLKEFVINCGNIITSTANIKLI-KDGKELEEVAKGFGPIDAAFKAIDNIVGGDFKLEDY 450
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VTEG DA+ V I+ +N ++G G D+V +S+KAY+ A
Sbjct: 451 SVESVTEGEDALGEAVVKIKRNN--------------EIYNGRGLSTDVVEASIKAYINA 496
Query: 543 LNKM 554
+NKM
Sbjct: 497 INKM 500
[107][TOP]
>UniRef100_C6ML81 2-isopropylmalate synthase n=1 Tax=Geobacter sp. M18
RepID=C6ML81_9DELT
Length = 515
Score = 129 bits (325), Expect = 1e-28
Identities = 74/185 (40%), Positives = 110/185 (59%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA K RL ELG+ LD+ L+N F RFKA+A+ KK V D DL A+V+D+ + +
Sbjct: 335 KHSGRHAFKKRLEELGHELDEAGLNNAFTRFKALADLKKEVYDEDLDAIVADQTKKIDEK 394
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL + +TCG+ ++T+TV++ + DG + +G GPVDA KA+ + K A LL+Y
Sbjct: 395 YKLSHITVTCGSFAVATATVQM-EIDGIQVRTAELGDGPVDATLKAIKKLAKRDAQLLQY 453
Query: 363 SMNAVTEGIDAIATTRVLI-RGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
++ ++T G DA+ V I GD N G G+ DI+ +S KAY+
Sbjct: 454 NVGSITGGTDALGEVTVRITEGDRN--------------PVIGRGSSTDIIEASAKAYID 499
Query: 540 ALNKM 554
ALN++
Sbjct: 500 ALNRL 504
[108][TOP]
>UniRef100_A4J181 2-isopropylmalate synthase n=1 Tax=Desulfotomaculum reducens MI-1
RepID=LEU1_DESRM
Length = 505
Score = 129 bits (324), Expect = 1e-28
Identities = 79/185 (42%), Positives = 107/185 (57%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA +DRL ELGY L++ +L+ F RFK +A++KK +TD DL A+V DE+
Sbjct: 330 KHSGRHAFRDRLEELGYHLNEEELNLAFSRFKVLADKKKEITDHDLQAMVEDEIKHIPDT 389
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDG-KEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
+ L + I+ GT + T+T+ L D KE AC G GPVDA YK VD I TL+
Sbjct: 390 YVLKYLHISTGTAVVPTATLGLQMGDELKEEAAC--GDGPVDAIYKTVDKITGISCTLVN 447
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y++NA+T G DA+ V IR E E+ + G G DI+ +S KAYV
Sbjct: 448 YAINAITGGKDALGDVTVKIR------------CEEKEKVYIGRGVSTDILEASAKAYVN 495
Query: 540 ALNKM 554
A+NK+
Sbjct: 496 AINKL 500
[109][TOP]
>UniRef100_A3YY55 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. WH 5701
RepID=A3YY55_9SYNE
Length = 540
Score = 129 bits (323), Expect = 2e-28
Identities = 73/184 (39%), Positives = 110/184 (59%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A + RL +LGY L+ L F RFK +A++K+ +TD DL A+VSD+ Q EA
Sbjct: 347 KLSGRSAFRARLEDLGYTLERDDLDEAFARFKELADRKREITDRDLEAIVSDQAQQTEAR 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+ L +Q++ GT T+TV L SDG E ++GTGPVDA +A++ + + P L+E+
Sbjct: 407 YVLKLVQVSTGTNLQPTATVTLTTSDGAELTEAAIGTGPVDAVCQALNSLARVPNELVEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VTEGIDA+ + +R ++G A DIVV++ +A+V A
Sbjct: 467 SVKSVTEGIDAMGEVTIRLRHHG--------------VLYAGHAADTDIVVAAAQAFVNA 512
Query: 543 LNKM 554
LN++
Sbjct: 513 LNRL 516
[110][TOP]
>UniRef100_C6E526 2-isopropylmalate synthase n=1 Tax=Geobacter sp. M21
RepID=C6E526_GEOSM
Length = 515
Score = 128 bits (322), Expect = 2e-28
Identities = 75/184 (40%), Positives = 105/184 (57%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA K RL ELG+ LD+ L+ F RFKA+A+ KK V D DL A+V DE E
Sbjct: 335 KHSGRHAFKKRLEELGHELDEEALNKAFTRFKALADLKKEVFDEDLDAIVLDEAKNIEEK 394
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL + +TCG+ ++T+TV++ + DG + A +G GPVDA KA+ + K LL+Y
Sbjct: 395 YKLSHITVTCGSFAVATATVQM-EIDGMQVRAAELGDGPVDATMKAIKKLAKRDVKLLQY 453
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++ A+T G DAI V I E G G+ DI+ +S KAY+ A
Sbjct: 454 NVGAITGGTDAIGEVTVRIT-------------EEDRTPVIGRGSSTDIIEASAKAYIDA 500
Query: 543 LNKM 554
LN++
Sbjct: 501 LNRL 504
[111][TOP]
>UniRef100_C9RAW9 2-isopropylmalate synthase n=1 Tax=Ammonifex degensii KC4
RepID=C9RAW9_9THEO
Length = 525
Score = 127 bits (320), Expect = 4e-28
Identities = 78/185 (42%), Positives = 106/185 (57%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA + RL ELGY L + +L+ F RFK + ++KK +TD DL+ALV +E+ Q
Sbjct: 339 KHSGRHAFRVRLRELGYELSEEELNAAFQRFKELCDRKKEITDDDLLALVEEEIGQVPPT 398
Query: 183 WKLLDMQITCGTLGLSTSTVKL-ADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++L I+ GT + T+TV L + KE AC G GPVDA YKA+D + L
Sbjct: 399 YELRYFHISSGTTVVPTATVALKIGEEVKEEAAC--GNGPVDAIYKAIDKLTGRHLRLDS 456
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
YS+ AVTEG DAI S T VT E +T+ G G D++ +S +AY+
Sbjct: 457 YSIEAVTEGKDAIG------------SVTVRVTDEERGKTYLGRGISTDVLEASARAYID 504
Query: 540 ALNKM 554
ALNK+
Sbjct: 505 ALNKL 509
[112][TOP]
>UniRef100_C7DAW2 2-isopropylmalate synthase n=1 Tax=Thalassiobium sp. R2A62
RepID=C7DAW2_9RHOB
Length = 519
Score = 127 bits (320), Expect = 4e-28
Identities = 78/184 (42%), Positives = 108/184 (58%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+ +++ELG+ L D QL ++F RFK +A++KK V D DLIAL+ EA+
Sbjct: 330 KHSGRAALRAKMSELGFDLSDNQLKDVFVRFKDLADRKKEVFDDDLIALMGASEPADEAI 389
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL M++ CGT G +++ L + +G EH G GPVDAA+ AV +V A L Y
Sbjct: 390 -KLKSMRVVCGTEGPQEASMTL-EVNGTEHTTTETGDGPVDAAFNAVKALVNHEARLQLY 447
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + D S +G A D VV+SV+AY+GA
Sbjct: 448 QVSAVTEGTDAQATVSVRLEEDGKIS--------------TGQSADTDTVVASVRAYIGA 493
Query: 543 LNKM 554
LN++
Sbjct: 494 LNRL 497
[113][TOP]
>UniRef100_Q8DJ32 2-isopropylmalate synthase n=1 Tax=Thermosynechococcus elongatus
BP-1 RepID=LEU1_THEEB
Length = 535
Score = 127 bits (320), Expect = 4e-28
Identities = 71/185 (38%), Positives = 111/185 (60%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR+A RL ELG+ L + +L+ F RFK +A++KK +TD DL A+ DE +
Sbjct: 352 KLSGRNAFATRLRELGFELSETELNKAFLRFKDLADKKKEITDWDLEAIAKDETQGIDLQ 411
Query: 183 -WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++L +Q++CG T+TV + G+E ++GTGPVDA Y+A++ +V+ P L+E
Sbjct: 412 GYQLEFVQVSCGDHARPTATVTVRTPSGEELTDAAIGTGPVDAVYRAINRVVQIPNRLIE 471
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
YS+ +VT GIDAI + + + +R +SG A DI+V+S +AY+
Sbjct: 472 YSVQSVTAGIDAIGEVTIRL--------------QHQDRIYSGHAANTDIIVASAQAYMN 517
Query: 540 ALNKM 554
ALN++
Sbjct: 518 ALNRL 522
[114][TOP]
>UniRef100_D0CPN4 2-isopropylmalate synthase n=1 Tax=Silicibacter lacuscaerulensis
ITI-1157 RepID=D0CPN4_9RHOB
Length = 526
Score = 127 bits (319), Expect = 6e-28
Identities = 78/184 (42%), Positives = 111/184 (60%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+D+L LGY + D QL ++F RFK +A++KK V D DLIAL+S + + +
Sbjct: 337 KHSGRAALRDKLETLGYEVGDNQLKDIFVRFKELADRKKEVFDDDLIALMSADDATNDHL 396
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+L+ M++TCGT G + +TV+L + DGK+ +A G GPVDA +KA+ I A L Y
Sbjct: 397 -QLVSMKVTCGTGGQAEATVEL-EVDGKDVIATEHGDGPVDATFKAIRAIYPNKAHLQLY 454
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + D + +G A D VV+S KAY+ A
Sbjct: 455 QVHAVTEGTDAQATVSVRLEEDGMIA--------------TGQSANTDTVVASAKAYISA 500
Query: 543 LNKM 554
LN++
Sbjct: 501 LNRL 504
[115][TOP]
>UniRef100_B6B711 2-isopropylmalate synthase n=1 Tax=Rhodobacterales bacterium Y4I
RepID=B6B711_9RHOB
Length = 528
Score = 127 bits (318), Expect = 7e-28
Identities = 79/184 (42%), Positives = 108/184 (58%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+D+L LGY + D QL ++F RFK +A++KK V D DLIAL+
Sbjct: 338 KHSGRAALRDKLEHLGYEVGDNQLKDVFVRFKELADRKKEVFDDDLIALMRTGTDAENDH 397
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
K++ M++ CGT G + +TV++ + DGK+ + G GPVDA +KA+ I A L Y
Sbjct: 398 LKIVSMKVVCGTGGPAEATVEM-EIDGKDVTETAEGDGPVDATFKAIRKIYPNTARLQLY 456
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + D N + TGES A D VV+S KAYV A
Sbjct: 457 QVHAVTEGTDAQATVSVRLEEDGNIA-----TGES---------ANTDTVVASAKAYVNA 502
Query: 543 LNKM 554
LN++
Sbjct: 503 LNRL 506
[116][TOP]
>UniRef100_B0TCR1 2-isopropylmalate synthase n=1 Tax=Heliobacterium modesticaldum
Ice1 RepID=LEU1_HELMI
Length = 512
Score = 127 bits (318), Expect = 7e-28
Identities = 75/185 (40%), Positives = 109/185 (58%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA ++RL ELGY LDD +L+ F RFKA+A++K+ +TD DL+ LV DE+
Sbjct: 330 KHSGRHAFRERLKELGYSLDDEKLTKAFARFKALADRKREITDEDLVVLVEDELRAFPEA 389
Query: 183 WKLLDMQITCGTLGLSTSTVKL-ADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
+ L + IT GT+ + T+TV+L + + E +C G GPVDAAYKA++ I A L
Sbjct: 390 YSLEYLHITSGTVLVPTATVRLRREEENFEEASC--GDGPVDAAYKAIEKITGTGARLAS 447
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y+++A T G D+ V + E R ++G G DI+V+S KAY+
Sbjct: 448 YAISATTAGEDSQGEVSVKL--------------EREGRFYTGRGVDTDIIVASAKAYLN 493
Query: 540 ALNKM 554
A+NK+
Sbjct: 494 AVNKI 498
[117][TOP]
>UniRef100_B3EBJ2 2-isopropylmalate synthase n=1 Tax=Geobacter lovleyi SZ
RepID=B3EBJ2_GEOLS
Length = 519
Score = 126 bits (316), Expect = 1e-27
Identities = 75/184 (40%), Positives = 109/184 (59%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA K RL ELG+ LDD L+ F RFKA+A+ KK V D DL A+V+DE + E
Sbjct: 341 KHSGRHAFKKRLEELGHDLDDEMLNRAFERFKALADLKKEVFDEDLDAIVTDE-SREEDQ 399
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL + +TCG+ ++T+TV++ + +GK +G GPVD+A+KA+ + K A L +Y
Sbjct: 400 YKLEHITVTCGSFAVATATVQM-EINGKPVRTAELGDGPVDSAFKAIRKLTKTKAKLTQY 458
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++ ++T G DA V + E T G GA DI+V+S KAY+ A
Sbjct: 459 NVGSITGGTDAQGEVTVRV--------------EEGGHTVVGKGASTDIIVASAKAYIHA 504
Query: 543 LNKM 554
LN++
Sbjct: 505 LNRL 508
[118][TOP]
>UniRef100_B5ING5 2-isopropylmalate synthase n=1 Tax=Cyanobium sp. PCC 7001
RepID=B5ING5_9CHRO
Length = 547
Score = 126 bits (316), Expect = 1e-27
Identities = 74/185 (40%), Positives = 111/185 (60%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQP-EA 179
KLSGR A + RL ELGY L L + F RFK +A++K+ +TD DL A+VS++V Q E
Sbjct: 347 KLSGRSAFRARLEELGYELSREDLDDAFARFKELADRKREITDRDLEAIVSEQVQQTDEG 406
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
+ L +Q++CGT T+TV L +DG E ++GTGPVDA +A++ + + P L+E
Sbjct: 407 RFTLKSVQVSCGTGLQPTATVTLLTADGAEISEAAIGTGPVDAVCQALNRLAQVPNELVE 466
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
+S+ +VTEGIDA+ + +R +SG A DIVV++ +A+V
Sbjct: 467 FSVKSVTEGIDAMGEVTIRLRHQG--------------VLYSGHAADTDIVVAAAQAFVN 512
Query: 540 ALNKM 554
ALN++
Sbjct: 513 ALNRL 517
[119][TOP]
>UniRef100_B9NRA6 2-isopropylmalate synthase n=1 Tax=Rhodobacteraceae bacterium KLH11
RepID=B9NRA6_9RHOB
Length = 522
Score = 124 bits (312), Expect = 4e-27
Identities = 76/184 (41%), Positives = 111/184 (60%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+D+L LGY + D QL ++F RFK +A++KK V D DLIAL++ + + +
Sbjct: 334 KHSGRAALRDKLETLGYEVGDNQLKDIFVRFKDLADRKKEVFDDDLIALMT--LDEADDY 391
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+L+ M++TCGT G + STV+L + DG++ +A G GPVDA ++A+ I A L Y
Sbjct: 392 LQLVSMKVTCGTGGQAESTVEL-EMDGEDVIATEHGDGPVDATFRAIRAIYPNKAHLQLY 450
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + D + +G A D VV+S KAY+ A
Sbjct: 451 QVHAVTEGTDAQATVSVRLEEDGMIA--------------TGQSANTDTVVASAKAYIHA 496
Query: 543 LNKM 554
LN++
Sbjct: 497 LNRL 500
[120][TOP]
>UniRef100_Q0FCE5 2-isopropylmalate synthase n=1 Tax=Rhodobacterales bacterium
HTCC2255 RepID=Q0FCE5_9RHOB
Length = 510
Score = 124 bits (311), Expect = 5e-27
Identities = 83/185 (44%), Positives = 111/185 (60%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSD-EVFQPEA 179
K SGR AL+ +L +LGY L D QL ++F RFKA+A++KK V D DL+ALVSD E
Sbjct: 331 KHSGRAALRSKLKDLGYDLGDNQLKDVFVRFKALADRKKEVYDDDLLALVSDEETNSAND 390
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++ +Q+TCGT G T+++ L D E+ ++G GPVDA +KAV + A L
Sbjct: 391 TIQVKSLQVTCGTEGPQTASLALI-IDKVEYSHKAIGDGPVDAVFKAVQALFPHQAHLQL 449
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y ++AVTEG DA AT V +R + N VTG+S A D VV+S KAYV
Sbjct: 450 YQVHAVTEGTDAQAT--VSVRMEEN---GKIVTGQS---------ADTDTVVASAKAYVN 495
Query: 540 ALNKM 554
ALNK+
Sbjct: 496 ALNKL 500
[121][TOP]
>UniRef100_B5YJS7 2-isopropylmalate synthase n=1 Tax=Thermodesulfovibrio yellowstonii
DSM 11347 RepID=B5YJS7_THEYD
Length = 504
Score = 123 bits (309), Expect = 8e-27
Identities = 69/184 (37%), Positives = 108/184 (58%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA K RL ELG+ L + +++ F RFK +A+QKK + + D+ ALVSDEV + V
Sbjct: 329 KHSGRHAFKKRLEELGFSLTEEEINRAFERFKKLADQKKYIFNEDIEALVSDEVLRIAEV 388
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L+D+++ GT T+TVK+ + ++ + S G GPVD+ Y+A+ + A L ++
Sbjct: 389 YQLIDLEVASGTKKKPTATVKMKINGDEKEITVS-GDGPVDSVYRAITELTGSKAELNKF 447
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
+ A+T G DA+ V++ E T G G+ DI+V+S KAY+ A
Sbjct: 448 EIKAITGGTDALGEVTVIL--------------EEGGHTVRGHGSDTDIIVASAKAYINA 493
Query: 543 LNKM 554
LNK+
Sbjct: 494 LNKL 497
[122][TOP]
>UniRef100_Q3J3Z9 2-isopropylmalate synthase n=1 Tax=Rhodobacter sphaeroides 2.4.1
RepID=Q3J3Z9_RHOS4
Length = 529
Score = 123 bits (308), Expect = 1e-26
Identities = 76/185 (41%), Positives = 109/185 (58%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPE-A 179
K SGR AL+ +L +LGY L D QL+++F RFKA+A++KK V D D++AL+ D+V E
Sbjct: 338 KHSGRAALRAKLKDLGYDLADNQLNDVFVRFKALADRKKEVYDDDIVALIQDQVTSAEHD 397
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
+L +++ CGT G + + L+ +G +H + G GPVDAA+ AV +I A L
Sbjct: 398 TLQLKRLRVVCGTDGPQEAEMTLS-VEGVDHAIDATGDGPVDAAFNAVKMIYPHHAKLHL 456
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y ++AVTEG DA AT V + D + +G A D VV+SVKAYV
Sbjct: 457 YQVHAVTEGTDAQATVSVRLEEDGKIA--------------TGQAADTDTVVASVKAYVN 502
Query: 540 ALNKM 554
ALN++
Sbjct: 503 ALNRL 507
[123][TOP]
>UniRef100_Q28L52 2-isopropylmalate synthase n=1 Tax=Jannaschia sp. CCS1
RepID=Q28L52_JANSC
Length = 519
Score = 123 bits (308), Expect = 1e-26
Identities = 78/186 (41%), Positives = 110/186 (59%), Gaps = 2/186 (1%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+ +L +LGY + D QL++LF RFKA+A++KK V D DLIALV+D E
Sbjct: 331 KHSGRAALRSKLKDLGYDMADNQLNDLFVRFKALADRKKEVFDDDLIALVTDAGSDGEGH 390
Query: 183 WKLLDMQITCGTLGLSTS--TVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLL 356
++ +++ CGT ++ T+++ D+D H A + G GPVDAA+ AV + A L
Sbjct: 391 LEVKFLRVICGTEAPQSADLTLRVGDTD---HQATAQGDGPVDAAFNAVKAVFPNEAALQ 447
Query: 357 EYSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYV 536
Y ++AVTEG+DA AT V + E R +G A D VV+SVKAYV
Sbjct: 448 LYQVSAVTEGMDAQATVTVRV--------------EEGGRIATGQSADTDTVVASVKAYV 493
Query: 537 GALNKM 554
ALN++
Sbjct: 494 NALNRL 499
[124][TOP]
>UniRef100_B0CEB7 2-isopropylmalate synthase n=1 Tax=Acaryochloris marina MBIC11017
RepID=B0CEB7_ACAM1
Length = 546
Score = 123 bits (308), Expect = 1e-26
Identities = 73/186 (39%), Positives = 112/186 (60%), Gaps = 2/186 (1%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR+A + RL ELG L + L+ F RFK +A++KK ++D DL A+V DE Q + +
Sbjct: 351 KHSGRNAFRTRLQELGMELSEQDLNKAFIRFKELADKKKEISDRDLEAIVKDET-QSQVI 409
Query: 183 --WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLL 356
++L +Q++CG T+TV + +E +VGTGPVDA Y+A++ +VK P L+
Sbjct: 410 GGFRLELVQVSCGDHACPTATVTICTPGNQELTDAAVGTGPVDAVYQAINRVVKVPNRLI 469
Query: 357 EYSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYV 536
E+S+ +VT GIDAI V IR + N + ++G A DI+V+S +AY+
Sbjct: 470 EFSVQSVTAGIDAIG--EVTIRLEQN------------GKIYAGYSANTDIIVASAQAYL 515
Query: 537 GALNKM 554
ALN++
Sbjct: 516 NALNRL 521
[125][TOP]
>UniRef100_A3PIF0 2-isopropylmalate synthase n=2 Tax=Rhodobacter sphaeroides
RepID=A3PIF0_RHOS1
Length = 529
Score = 123 bits (308), Expect = 1e-26
Identities = 76/185 (41%), Positives = 109/185 (58%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPE-A 179
K SGR AL+ +L +LGY L D QL+++F RFKA+A++KK V D D++AL+ D+V E
Sbjct: 338 KHSGRAALRAKLKDLGYDLADNQLNDVFVRFKALADRKKEVYDDDIVALIQDQVTSAEHD 397
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
+L +++ CGT G + + L+ +G +H + G GPVDAA+ AV +I A L
Sbjct: 398 TLQLKRLRVVCGTDGPQEAEMTLS-VEGVDHAIDATGDGPVDAAFNAVKMIYPHHAKLHL 456
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y ++AVTEG DA AT V + D + +G A D VV+SVKAYV
Sbjct: 457 YQVHAVTEGTDAQATVSVRLEEDGKIA--------------TGQAADTDTVVASVKAYVN 502
Query: 540 ALNKM 554
ALN++
Sbjct: 503 ALNRL 507
[126][TOP]
>UniRef100_C6QKF2 2-isopropylmalate synthase n=1 Tax=Geobacillus sp. Y4.1MC1
RepID=C6QKF2_9BACI
Length = 515
Score = 122 bits (306), Expect = 2e-26
Identities = 68/185 (36%), Positives = 109/185 (58%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQP-EA 179
K SGRHAL++R+ ELGY L D +++ LF RFK +A++KK +TD DL+AL+ +E F +
Sbjct: 329 KHSGRHALRNRVEELGYKLSDEEINKLFVRFKELADKKKDITDDDLVALIFEEKFDHFKD 388
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++L +Q+ GT + T+ V L D +G E + G G V+A Y ++ K P TLL+
Sbjct: 389 FYQLTSLQVQYGTNQIPTAVVVLKDGEGNEIQEAATGAGSVEALYNTLERCFKTPVTLLD 448
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y + +V+ G DA+A V +R ++ + SG G D++ +S KAY+
Sbjct: 449 YRIESVSGGRDALAQVFVKVRVNDIET--------------SGRGTAQDVLEASAKAYIN 494
Query: 540 ALNKM 554
A+N++
Sbjct: 495 AVNRV 499
[127][TOP]
>UniRef100_A4EQL7 2-isopropylmalate synthase n=1 Tax=Roseobacter sp. SK209-2-6
RepID=A4EQL7_9RHOB
Length = 524
Score = 122 bits (306), Expect = 2e-26
Identities = 78/184 (42%), Positives = 108/184 (58%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+D+L LG+ + D QL ++F RFK +A++KK V D DLIAL+
Sbjct: 334 KHSGRAALRDKLEHLGFEVGDNQLKDVFVRFKELADRKKEVFDDDLIALMRSGEDAENDY 393
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+++ M++ CGT G + ST+++ + DGK+ A S G GPVDA +KA+ I A L Y
Sbjct: 394 LQIVSMKVVCGTGGPAESTLEM-EVDGKDVSATSEGDGPVDATFKAIRKIHPNTARLQLY 452
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + D + TGES A D VV+S KAYV A
Sbjct: 453 QVHAVTEGTDAQATVSVRLEEDGVIA-----TGES---------ANTDTVVASAKAYVNA 498
Query: 543 LNKM 554
LN++
Sbjct: 499 LNRL 502
[128][TOP]
>UniRef100_A5V3R3 2-isopropylmalate synthase n=1 Tax=Sphingomonas wittichii RW1
RepID=A5V3R3_SPHWW
Length = 513
Score = 122 bits (305), Expect = 2e-26
Identities = 74/185 (40%), Positives = 107/185 (57%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR A + +L ELGY L D + F RFKA+A+ KK V D D++ALV DEV +
Sbjct: 330 KHSGRAAFRQKLEELGYALGDNAFQDAFGRFKALADAKKAVYDEDIVALVDDEVLRGHDS 389
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE- 359
++ ++++ CG+ G + + L + DG+E + G GPVDA + A+ +IV +++LE
Sbjct: 390 IQVKEVEVYCGSNGPQRAILTL-EVDGEEKTVTARGNGPVDALFNAIRMIVPHDSSVLER 448
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y ++AVT G DA A VL+ + RT G GA D +V+SV+AYV
Sbjct: 449 YEVHAVTGGTDAQAEVSVLLSENG--------------RTTRGRGAHQDTMVASVRAYVN 494
Query: 540 ALNKM 554
ALNKM
Sbjct: 495 ALNKM 499
[129][TOP]
>UniRef100_A6CAS9 2-isopropylmalate synthase n=1 Tax=Planctomyces maris DSM 8797
RepID=A6CAS9_9PLAN
Length = 507
Score = 122 bits (305), Expect = 2e-26
Identities = 66/183 (36%), Positives = 104/183 (56%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA +DR+ LG+ LD+ +F F A+A++KK + D+D++AL+ ++
Sbjct: 332 KHSGRHAFRDRIQSLGHTLDEETFERIFNEFIALADKKKEIYDSDIVALIENQASDMPEK 391
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
WK++ + GT ++T+T++LAD GK H + G GPVDA ++A++ I A L +Y
Sbjct: 392 WKIVRFHTSAGTGTIATATIELADETGKIHCDAATGDGPVDAVFRALERISGITAALDQY 451
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
+ +V+ G DA RV +R + GE F+G DI+ SS KAY+ A
Sbjct: 452 HVGSVSSGKDAQGEVRVEVR----------INGE----LFTGRSVSTDIIESSAKAYLQA 497
Query: 543 LNK 551
+NK
Sbjct: 498 INK 500
[130][TOP]
>UniRef100_Q5LWC0 2-isopropylmalate synthase n=1 Tax=Ruegeria pomeroyi
RepID=Q5LWC0_SILPO
Length = 524
Score = 121 bits (304), Expect = 3e-26
Identities = 76/184 (41%), Positives = 110/184 (59%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+D+L LGY + D QL ++F RFK +A++KK V D D+IAL+ +
Sbjct: 334 KHSGRAALRDKLEHLGYEVGDNQLKDIFVRFKELADRKKEVFDDDVIALMRSGENAEQDH 393
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+L+ M++ CGT G + +TV++ + DGK+ A + G GPVDA++KA+ + A L Y
Sbjct: 394 LQLVSMKVICGTGGPAEATVEM-EIDGKDVSATAHGDGPVDASFKAIRALHPNEAHLQLY 452
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + D + TGES A D VV+S KAY+ A
Sbjct: 453 QVHAVTEGTDAQATVSVRLEEDGMIA-----TGES---------ANTDTVVASAKAYINA 498
Query: 543 LNKM 554
LN++
Sbjct: 499 LNRL 502
[131][TOP]
>UniRef100_A4WSX7 2-isopropylmalate synthase n=1 Tax=Rhodobacter sphaeroides ATCC
17025 RepID=A4WSX7_RHOS5
Length = 529
Score = 120 bits (301), Expect = 7e-26
Identities = 74/185 (40%), Positives = 109/185 (58%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPE-A 179
K SGR AL+ +L +LGY L + QL+++F RFKA+A++KK V D D++AL+ D+ E
Sbjct: 338 KHSGRAALRAKLKDLGYDLGENQLNDVFVRFKALADRKKEVFDDDIVALIQDQATSAEHD 397
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
V +L +++ CGT G + + L+ +G +H + G GPVDAA+ AV ++ A L
Sbjct: 398 VLQLKRLRVVCGTDGPQEAEMTLS-VEGVDHSIDATGDGPVDAAFNAVKMLYPHHARLHL 456
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y ++AVTEG DA AT V + D + +G A D VV+SVKAYV
Sbjct: 457 YQVHAVTEGTDAQATVSVRLEEDGKIA--------------TGQAADTDTVVASVKAYVN 502
Query: 540 ALNKM 554
ALN++
Sbjct: 503 ALNRL 507
[132][TOP]
>UniRef100_A3XD03 2-isopropylmalate synthase n=1 Tax=Roseobacter sp. MED193
RepID=A3XD03_9RHOB
Length = 524
Score = 120 bits (301), Expect = 7e-26
Identities = 75/184 (40%), Positives = 108/184 (58%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+D+L+ LG+ + D QL +LF RFK +A++KK V D D++AL+
Sbjct: 334 KHSGRAALRDKLSTLGFDVGDNQLKDLFVRFKELADRKKEVFDDDIVALMRSGEDAENDH 393
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+L+ M++ CGT G + +TV++ + DG++ A G GPVDA +KA+ + A L Y
Sbjct: 394 LQLVSMKVICGTGGPAEATVEM-EIDGQDLTAVESGDGPVDATFKAIRKLYPNTARLQLY 452
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
+NAVTEG DA AT V + D + TGES A D VV+S KAY+ A
Sbjct: 453 QVNAVTEGTDAQATVSVRLEEDGIIA-----TGES---------ANTDTVVASAKAYINA 498
Query: 543 LNKM 554
LN++
Sbjct: 499 LNRV 502
[133][TOP]
>UniRef100_C9CV77 2-isopropylmalate synthase n=1 Tax=Silicibacter sp. TrichCH4B
RepID=C9CV77_9RHOB
Length = 527
Score = 120 bits (300), Expect = 9e-26
Identities = 75/184 (40%), Positives = 107/184 (58%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+D+L LGY + D QL +LF RFK +A++KK V D D+IAL+ + + +
Sbjct: 338 KHSGRAALRDKLTNLGYEIGDNQLKDLFVRFKELADRKKEVFDDDIIALMRTSGDEDDHL 397
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL+ M++ CGT G + STV++ + DGK+ + G GPVDA +KA+ I A L Y
Sbjct: 398 -KLVSMKVVCGTGGPAESTVEM-EVDGKDVTETAEGDGPVDATFKAIRKIHPNAAHLQLY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + D + +G A D VV+S AY+ A
Sbjct: 456 QVHAVTEGTDAQATVSVRLEEDGVIA--------------TGDSANTDTVVASAMAYIDA 501
Query: 543 LNKM 554
LN++
Sbjct: 502 LNRL 505
[134][TOP]
>UniRef100_B7RGZ1 2-isopropylmalate synthase n=1 Tax=Roseobacter sp. GAI101
RepID=B7RGZ1_9RHOB
Length = 523
Score = 120 bits (300), Expect = 9e-26
Identities = 74/184 (40%), Positives = 98/184 (53%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+ +L LGY L D QL ++F RFK +A++KK + D DLIAL+
Sbjct: 334 KHSGRAALRSKLENLGYELGDNQLKDVFVRFKELADRKKEIYDEDLIALMRTATDPESDR 393
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL M + CGT G + + + L DG EH G GPVDA++ + +V A L Y
Sbjct: 394 IKLKSMHVVCGTEGPNVAKMTLI-VDGAEHSTEQTGDGPVDASFNCIKALVDHSARLQLY 452
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
+NAVTEG DA AT V + D R +G A D VVSS +AY+ A
Sbjct: 453 QVNAVTEGTDAQATVSVRLEEDG--------------RIVTGQAANTDTVVSSAQAYIHA 498
Query: 543 LNKM 554
LN++
Sbjct: 499 LNRL 502
[135][TOP]
>UniRef100_B8I1T7 2-isopropylmalate synthase n=1 Tax=Clostridium cellulolyticum H10
RepID=LEU1_CLOCE
Length = 508
Score = 120 bits (300), Expect = 9e-26
Identities = 73/183 (39%), Positives = 103/183 (56%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHA +DRL E+GY L D ++ F +FK +A++KK VTD D+ ALV + + PE +
Sbjct: 330 KLSGRHAFEDRLKEMGYSLSDEEVKTAFAKFKDLADKKKVVTDKDIEALVDENIAVPE-I 388
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+ + QI G +STSTV + D + + G GPVDAA+ AV+ A L+ Y
Sbjct: 389 FVIDSFQINSGNKMISTSTVSVR-KDEEIITEAATGDGPVDAAFNAVERATGVNAELVHY 447
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
+ AVTEG DA+ V I +N+ F G G DI+ +SVKAY+ A
Sbjct: 448 RIKAVTEGKDALGEVTVKISNNNS--------------IFMGKGVSTDIIEASVKAYLNA 493
Query: 543 LNK 551
+N+
Sbjct: 494 INR 496
[136][TOP]
>UniRef100_A1AL90 2-isopropylmalate synthase n=1 Tax=Pelobacter propionicus DSM 2379
RepID=A1AL90_PELPD
Length = 518
Score = 119 bits (299), Expect = 1e-25
Identities = 71/184 (38%), Positives = 110/184 (59%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA K RL ELG+ LDD L+ F RFKA+A+ KK V D DL A+V+DE + E +
Sbjct: 340 KHSGRHAFKKRLQELGHELDDEMLNRAFVRFKALADLKKEVFDEDLDAIVADE-SREEEM 398
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL+ + ++CG+L ++T+TVK+ + +G+ A +G GPVDA KA+ + K A L ++
Sbjct: 399 YKLVLLNVSCGSLSVATATVKM-EINGQLLRAAELGDGPVDATLKAIRKLTKSKAKLEQF 457
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++ ++T G DA + + N+ G G+ DI+ +S KA+V A
Sbjct: 458 NVGSITGGTDAQGEVTMRVSDGNH--------------LVVGKGSSTDIIEASAKAFVHA 503
Query: 543 LNKM 554
LN++
Sbjct: 504 LNRL 507
[137][TOP]
>UniRef100_C6PQI3 2-isopropylmalate synthase n=1 Tax=Clostridium carboxidivorans P7
RepID=C6PQI3_9CLOT
Length = 514
Score = 119 bits (299), Expect = 1e-25
Identities = 74/185 (40%), Positives = 104/185 (56%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYV-LDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEA 179
K SGRHA ++RL ELGY L +++ F +FK +A++KK V+D D+ ALV E FQ
Sbjct: 330 KHSGRHAFEERLKELGYANLSMDKINEAFIKFKDLADKKKSVSDEDIEALVIQEAFQIPE 389
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++KL QI+ G L+TSTVKL D K A S+G GPVDA +KA++ + L
Sbjct: 390 LFKLEYFQISSGNSTLATSTVKLGFEDKKLEEA-SLGDGPVDATFKAIEKAIGIDVILKN 448
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y + A+ G DA+ + I DN R +SG G D++ SS KA++
Sbjct: 449 YFLKAIGSGKDALGEVTLKIEKDN--------------RIYSGKGISTDVIESSAKAFIN 494
Query: 540 ALNKM 554
A+NKM
Sbjct: 495 AINKM 499
[138][TOP]
>UniRef100_Q5KWJ3 2-isopropylmalate synthase n=3 Tax=Geobacillus RepID=LEU1_GEOKA
Length = 515
Score = 119 bits (299), Expect = 1e-25
Identities = 68/185 (36%), Positives = 106/185 (57%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQP-EA 179
K SGRHAL++R+ ELGY L D +++ LF RFK +A++KK +TD DLIAL+ +E F +
Sbjct: 329 KHSGRHALRNRVEELGYTLSDEEINQLFVRFKELADKKKDITDDDLIALIFEEKFDHFKD 388
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++L +Q+ GT + T+ V L D G E + G G V+A Y ++ + P TLL+
Sbjct: 389 FYQLSSIQVQYGTNQIPTAVVVLKDGKGNEIQEAATGAGSVEALYNTLERCFQTPVTLLD 448
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y + +V G DA+A V +R + + SG G D++ +S KAY+
Sbjct: 449 YRIESVGGGRDALAQVFVKVRAHDIET--------------SGRGTAQDVLEASAKAYIN 494
Query: 540 ALNKM 554
A+N++
Sbjct: 495 AINRV 499
[139][TOP]
>UniRef100_B2IFN7 2-isopropylmalate synthase n=1 Tax=Beijerinckia indica subsp.
indica ATCC 9039 RepID=B2IFN7_BEII9
Length = 532
Score = 119 bits (298), Expect = 2e-25
Identities = 73/184 (39%), Positives = 100/184 (54%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA K++L ELGY L + L F RFK +A++KK V D DLIALV DE+
Sbjct: 349 KHSGRHAFKEKLKELGYELGENALEEAFARFKDLADRKKIVYDEDLIALVDDEIIHAHDR 408
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL+ + + GT G ++ + L DG E + G GP+DA + AV +V A L Y
Sbjct: 409 IKLVALTVIAGTKGPQSAALTLT-IDGVEQTHQATGNGPIDAIFNAVQALVPHGAVLELY 467
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVT+G DA A V + D +T + GA D +V+S KAY+ A
Sbjct: 468 QVHAVTKGTDAQAEVSVRLSEDG--------------KTVTARGADPDTLVASAKAYIAA 513
Query: 543 LNKM 554
LNK+
Sbjct: 514 LNKL 517
[140][TOP]
>UniRef100_B7QYF0 2-isopropylmalate synthase n=1 Tax=Ruegeria sp. R11
RepID=B7QYF0_9RHOB
Length = 523
Score = 119 bits (298), Expect = 2e-25
Identities = 76/184 (41%), Positives = 110/184 (59%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+D+L++LG+ + D QL +LF RFK +A++KK V D D+IAL+ + +
Sbjct: 334 KHSGRAALRDKLSQLGFEVGDNQLKDLFVRFKELADRKKEVFDDDIIALMRTGGDDDDHL 393
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL+ M++ CGT G + ST+++ + DGK+ + G GPVDA +KA+ I A L Y
Sbjct: 394 -KLVSMKVVCGTGGPAESTIEM-EVDGKDVTEAAEGDGPVDATFKAIRKIHPNAAHLQLY 451
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + D + TGES A D VV+S AY+ A
Sbjct: 452 QVHAVTEGTDAQATVSVRLEEDGVIA-----TGES---------ANTDTVVASAAAYISA 497
Query: 543 LNKM 554
LN++
Sbjct: 498 LNRL 501
[141][TOP]
>UniRef100_A3EQC8 2-isopropylmalate synthase n=1 Tax=Leptospirillum rubarum
RepID=A3EQC8_9BACT
Length = 532
Score = 119 bits (298), Expect = 2e-25
Identities = 74/184 (40%), Positives = 101/184 (54%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHAL DRL +GY LD + +F RFK +A+QKK + + DL L+++E Q
Sbjct: 337 KHSGRHALHDRLKAMGYSLDGEEFERVFSRFKKLADQKKELYEEDLEVLLTEEESQTRDR 396
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+ L + ++ GT T+TV L + DG EH +G GPVDA Y+ V I A L+ Y
Sbjct: 397 FVLKRLHVSGGTEIPPTATVVL-ERDGVEHRMAGLGDGPVDAIYRTVSKITATNARLVSY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ A+T G DA+ V I GD S G GA DI+V+S KAY+ A
Sbjct: 456 SVKAITGGTDALGEVTVRIEGDGLLS--------------IGQGADTDILVASAKAYLAA 501
Query: 543 LNKM 554
LN++
Sbjct: 502 LNRL 505
[142][TOP]
>UniRef100_UPI0001695207 2-isopropylmalate synthase n=1 Tax=Paenibacillus larvae subsp.
larvae BRL-230010 RepID=UPI0001695207
Length = 515
Score = 119 bits (297), Expect = 2e-25
Identities = 64/184 (34%), Positives = 107/184 (58%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA +++L +LGYVL++ QL+ F +FK +A++KK V D D+ A++ +++ Q V
Sbjct: 329 KHSGRHAFREKLVDLGYVLNEDQLNTAFAKFKKLADKKKNVLDEDIRAIIDEKLIQVPEV 388
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+ L MQ++ G + T+TV++ DG +VG G VDA Y A+D +E L +Y
Sbjct: 389 FVLDTMQVSYGNQSVPTATVRILTQDGGRLEEAAVGNGSVDAIYNAIDKATREEVELADY 448
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
+++V++G DA+ V+++ YS G G DI+ +S KAY+ A
Sbjct: 449 KIHSVSQGQDALGEVHVMLK-QYGYS-------------VLGRGVSTDILEASAKAYIDA 494
Query: 543 LNKM 554
+N++
Sbjct: 495 VNRL 498
[143][TOP]
>UniRef100_Q2RG97 2-isopropylmalate synthase n=1 Tax=Moorella thermoacetica ATCC
39073 RepID=Q2RG97_MOOTA
Length = 517
Score = 119 bits (297), Expect = 2e-25
Identities = 71/185 (38%), Positives = 104/185 (56%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHAL+ RL ELG+ L + +L F RFK +A++KK ++D DL A+V EV +
Sbjct: 333 KHSGRHALRSRLEELGFKLTEAELDKAFARFKELADRKKEISDRDLEAIVEHEVKRIPEK 392
Query: 183 WKLLDMQITCGTLGLSTSTVKL-ADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
+ L + I+ G + T+T+ + + KE AC G GPVDAA+KA+D + + P L
Sbjct: 393 FVLEHIHISTGNRVVPTATIGIRVGEELKEEAAC--GEGPVDAAFKAIDKLTRIPVCLKS 450
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y++NAVT G DA+ V I D R F G G D++ +S +AY+
Sbjct: 451 YNLNAVTGGKDAVGEVTVKIEYDG--------------RVFIGRGISTDVLEASARAYLN 496
Query: 540 ALNKM 554
A+NK+
Sbjct: 497 AINKV 501
[144][TOP]
>UniRef100_B8EP66 2-isopropylmalate synthase n=1 Tax=Methylocella silvestris BL2
RepID=B8EP66_METSB
Length = 526
Score = 119 bits (297), Expect = 2e-25
Identities = 72/184 (39%), Positives = 102/184 (55%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA KD+L ELGY L D L + F RFK +A++KK V D DL+ALV DE+
Sbjct: 344 KHSGRHAFKDKLRELGYELADNALHDAFVRFKDLADRKKVVYDEDLMALVDDEIVHAHDR 403
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL+D+ + GT G ++ + L D DG + G GPVDA + A+ +V A L +
Sbjct: 404 IKLVDLTVFAGTKGPQSAALTL-DIDGTHVTHQATGNGPVDAIFNAIQALVPHGAVLELF 462
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVT+G DA A V + D +T + GA D +V++ KAY+ +
Sbjct: 463 QVHAVTKGTDAQAEVSVRLAEDG--------------KTVTAKGADPDTLVAAAKAYIAS 508
Query: 543 LNKM 554
LNK+
Sbjct: 509 LNKL 512
[145][TOP]
>UniRef100_B9DMJ6 2-isopropylmalate synthase n=1 Tax=Staphylococcus carnosus subsp.
carnosus TM300 RepID=LEU1_STACT
Length = 510
Score = 119 bits (297), Expect = 2e-25
Identities = 67/180 (37%), Positives = 105/180 (58%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSG+HA ++L +LGY + + LF +FK++A++KK V+D D+ ALV + A
Sbjct: 329 KLSGKHAFAEKLKQLGYDITAEKQVELFKQFKSIADKKKNVSDHDVHALVQGHSHETNAA 388
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+++ +Q+ + G+ ++ V L D +GKE+ + ++GTG + A Y AVD I K P+ LL Y
Sbjct: 389 YQVETLQLQFVSEGVQSAVVVLKDHEGKEYPSAAIGTGSIVAVYNAVDQIFKAPSELLNY 448
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
+ +VTEG DA A V IR D +T+ G G D++++S KAYV A
Sbjct: 449 QITSVTEGSDAQAQVNVEIRIDG--------------KTYYGIGVDHDVLLASCKAYVEA 494
[146][TOP]
>UniRef100_C1ZZQ9 2-isopropylmalate synthase n=1 Tax=Sulfurospirillum deleyianum DSM
6946 RepID=C1ZZQ9_SULDE
Length = 520
Score = 118 bits (296), Expect = 3e-25
Identities = 69/183 (37%), Positives = 112/183 (61%), Gaps = 1/183 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA KD+LN LGY L D +++ F RFK +A+QKK + D DL ALV+DE+ + V
Sbjct: 331 KHSGRHAFKDKLNSLGYELKDEEINEAFERFKILADQKKDIFDDDLRALVADEITKIPQV 390
Query: 183 WKLLDMQIT-CGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++L+ +Q++ C GL ++ V ++ +GKE ++G G +DA +K +D + L +
Sbjct: 391 FELVRLQLSDCSPGGLPSAAVTIS-HEGKEITDAAIGNGTMDAIFKVIDRVCGVSGELRD 449
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y ++AV++G DA+A RVL++ V + + G G +D ++++ KAY+G
Sbjct: 450 YKVDAVSQGKDAMA--RVLVK----------VVFDESKPAIMGHGLSVDTMLATAKAYIG 497
Query: 540 ALN 548
ALN
Sbjct: 498 ALN 500
[147][TOP]
>UniRef100_C5D5M0 2-isopropylmalate synthase n=1 Tax=Geobacillus sp. WCH70
RepID=LEU1_GEOSW
Length = 515
Score = 118 bits (296), Expect = 3e-25
Identities = 67/185 (36%), Positives = 107/185 (57%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQP-EA 179
K SGRHAL++R+ ELGY L D +++ LF RFK +A++KK +TD DL+AL+ +E F +
Sbjct: 329 KHSGRHALRNRVEELGYTLSDEEVNKLFVRFKELADKKKDITDDDLVALIFEEKFDHFKD 388
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++L +Q+ GT + T+ V L D G E + G G V+A Y ++ K TLL+
Sbjct: 389 FYQLSSLQVQYGTNQIPTAVVVLKDGQGNEIQEAATGAGSVEALYNTLERCFKTSVTLLD 448
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y + +V+ G DA+A V +R ++ + SG G D++ +S KAY+
Sbjct: 449 YRIESVSGGRDALAQVFVKVRVNDIET--------------SGRGTAQDVLEASAKAYIN 494
Query: 540 ALNKM 554
A+N++
Sbjct: 495 AVNRV 499
[148][TOP]
>UniRef100_B6AN22 2-isopropylmalate synthase AA and pyruvate n=1 Tax=Leptospirillum
sp. Group II '5-way CG' RepID=B6AN22_9BACT
Length = 532
Score = 118 bits (295), Expect = 3e-25
Identities = 74/184 (40%), Positives = 101/184 (54%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHAL DRL +GY LD + +F RFK +A+QKK + + DL L+++E Q
Sbjct: 337 KHSGRHALHDRLKAMGYSLDGEEFERVFSRFKKLADQKKELYEEDLEVLLTEEESQTRDR 396
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+ L + ++ GT T+TV L + DG EH +G GPVDA Y+ V I A L+ Y
Sbjct: 397 FVLKRLHVSGGTEIPPTATVVL-ERDGVEHRMAGLGDGPVDAIYRTVSKITATNARLVSY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ A+T G DA+ V I GD S G GA DI+V+S KAY+ A
Sbjct: 456 SVKAITGGTDALGEVTVRIEGDGLLS--------------IGQGADTDILVASAKAYLVA 501
Query: 543 LNKM 554
LN++
Sbjct: 502 LNRL 505
[149][TOP]
>UniRef100_A3JMT2 2-isopropylmalate synthase n=1 Tax=Rhodobacterales bacterium
HTCC2150 RepID=A3JMT2_9RHOB
Length = 524
Score = 118 bits (295), Expect = 3e-25
Identities = 76/185 (41%), Positives = 102/185 (55%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+ +L ELG+ L D QL ++F RFK +A++KK + DLIAL+ DE E
Sbjct: 334 KHSGRAALRSKLEELGFELGDNQLKDVFVRFKELADRKKEIFSDDLIALMRDEAATGEGN 393
Query: 183 WKLL-DMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++ +Q+ CGT G T+ + + D DG E A + G GPVDA++ AV + A L
Sbjct: 394 HLVIKSLQVVCGTSGPQTADL-VMDVDGVEKSAHATGDGPVDASFNAVKALFPHSARLQL 452
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y ++AVTEG DA AT V + D SG A D VV+S KAYV
Sbjct: 453 YQVSAVTEGTDAQATVTVRMEEDG--------------YIVSGQSADTDTVVASAKAYVA 498
Query: 540 ALNKM 554
ALN +
Sbjct: 499 ALNSL 503
[150][TOP]
>UniRef100_B1X5H2 2-isopropylmalate synthase n=1 Tax=Paulinella chromatophora
RepID=B1X5H2_PAUCH
Length = 548
Score = 118 bits (295), Expect = 3e-25
Identities = 66/184 (35%), Positives = 106/184 (57%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A K RL ELGY L+ +L F FK +A+ K+ VTD D+ ++S+ + QPE V
Sbjct: 347 KLSGRSAFKVRLKELGYHLNPEELDECFTLFKELADGKRNVTDQDIELIISEHIQQPEEV 406
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL +Q++CG+ T+TV + +D E ++GTGP+DA Y+ ++ IV P L E+
Sbjct: 407 YKLKLVQVSCGSTLCPTATVTVQKNDNTEITKAAIGTGPIDAVYRTLNEIVGMPNELTEF 466
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT GI+ + +R + +SG + DIVV++ +A + A
Sbjct: 467 SVKSVTAGINGKGEVTIRLR--------------HKKIIYSGHSSHADIVVAATQACLNA 512
Query: 543 LNKM 554
+N++
Sbjct: 513 INRL 516
[151][TOP]
>UniRef100_Q1GEA2 2-isopropylmalate synthase n=1 Tax=Ruegeria sp. TM1040
RepID=Q1GEA2_SILST
Length = 527
Score = 117 bits (294), Expect = 4e-25
Identities = 73/184 (39%), Positives = 108/184 (58%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+D+L+ LG+ + D QL ++F RFK +A++KK V D D+IAL+ + + +
Sbjct: 338 KHSGRAALRDKLSSLGFEIGDNQLKDVFVRFKELADRKKEVFDDDIIALMRTSGDEDDHL 397
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL+ M++ CGT G + STV++ + DGK+ + G GPVDA +KA+ I A L Y
Sbjct: 398 -KLVSMKVVCGTGGPAESTVEM-EVDGKDVTETAEGDGPVDATFKAIRKIHPNAAHLQLY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + D + +G A D VV+S AY+ A
Sbjct: 456 QVHAVTEGTDAQATVSVRLEEDGVIA--------------TGDSANTDTVVASAMAYIDA 501
Query: 543 LNKM 554
LN++
Sbjct: 502 LNRL 505
[152][TOP]
>UniRef100_C8S015 2-isopropylmalate synthase n=1 Tax=Rhodobacter sp. SW2
RepID=C8S015_9RHOB
Length = 525
Score = 117 bits (294), Expect = 4e-25
Identities = 73/185 (39%), Positives = 107/185 (57%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDE-VFQPEA 179
K SGR AL+ +L +LG+ L D QL+++F RFKA+A++KK V D DLIAL+ D+
Sbjct: 334 KHSGRAALRMKLRDLGFDLADNQLNDVFVRFKALADRKKEVYDDDLIALMQDQGTHAAHD 393
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
+L +++ CGT G + + +A +G +H + G GPVDA++ AV ++ A L
Sbjct: 394 TLQLKRLRVVCGTEGPQEAELTMA-IEGVDHAIDATGDGPVDASFNAVKMLYPHGARLQL 452
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y ++AVTEG DA AT V + D R +G A D VV+SVKAY+
Sbjct: 453 YQVHAVTEGTDAQATVSVRLEEDG--------------RIATGQSADTDTVVASVKAYIN 498
Query: 540 ALNKM 554
ALN++
Sbjct: 499 ALNRL 503
[153][TOP]
>UniRef100_A9FHR3 2-isopropylmalate synthase n=2 Tax=Phaeobacter gallaeciensis
RepID=A9FHR3_9RHOB
Length = 523
Score = 117 bits (292), Expect = 7e-25
Identities = 73/184 (39%), Positives = 112/184 (60%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+D+L++LG+ + D QL +LF RFK +A++KK V D D+IAL+ + + +
Sbjct: 334 KHSGRAALRDKLSQLGFEVGDNQLKDLFVRFKELADRKKEVFDDDIIALMRTSGDEDDHL 393
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL+ M++ CGT G + +T+++ + +GK+ + G GPVDAA++A+ I A L Y
Sbjct: 394 -KLVSMKVVCGTGGPAEATLEM-EVEGKDVSETAEGDGPVDAAFRAIRKIHPNSAHLQLY 451
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + +N +T G A D VV+S AY+GA
Sbjct: 452 QVHAVTEGTDAQATVSVRLE-ENGVIAT-------------GESANTDTVVASAAAYIGA 497
Query: 543 LNKM 554
LN++
Sbjct: 498 LNRL 501
[154][TOP]
>UniRef100_B1H0A7 2-isopropylmalate synthase n=1 Tax=uncultured Termite group 1
bacterium phylotype Rs-D17 RepID=LEU1_UNCTG
Length = 516
Score = 117 bits (292), Expect = 7e-25
Identities = 69/189 (36%), Positives = 109/189 (57%), Gaps = 6/189 (3%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA R+ +LGY LD+ L +LF +FK +A++KK V D D+IAL+ ++ +
Sbjct: 331 KHSGRHAFFKRIKDLGYKLDEKTLEHLFEKFKILADKKKTVFDDDIIALIEEDTSSGKET 390
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHV------ACSVGTGPVDAAYKAVDLIVKEP 344
+ L + T GT + T+TVK++ S+G + A + G+GPVDA YKA+D I+
Sbjct: 391 FILNYLSATSGTGTIPTATVKISKSEGNKKTKSITLQAAACGSGPVDATYKAIDKIINMD 450
Query: 345 ATLLEYSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSV 524
L ++S+ +V+ G DA+ V+++ + Y T +SG G DI+ +S
Sbjct: 451 IKLTDFSLRSVSSGEDALG--EVVLKAE--YKGT----------IYSGKGTSTDIIEASA 496
Query: 525 KAYVGALNK 551
KAY+ A+NK
Sbjct: 497 KAYIQAINK 505
[155][TOP]
>UniRef100_B7GH19 2-isopropylmalate synthase n=1 Tax=Anoxybacillus flavithermus WK1
RepID=LEU1_ANOFW
Length = 514
Score = 117 bits (292), Expect = 7e-25
Identities = 67/185 (36%), Positives = 105/185 (56%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQP-EA 179
K SGRHA + R+ ELGY L + +++ LF RFK +A++KK +TD DLIAL+ DE +
Sbjct: 329 KHSGRHAFRTRIQELGYSLTEEEVNRLFVRFKDLADKKKDITDDDLIALILDEKLDTYKN 388
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++L +Q+ GT + T+ V L D +G + + G G V+A Y A++ ++ P TLL+
Sbjct: 389 FYQLCSIQVQYGTNQIPTAVVVLKDGEGNDIQEAATGAGSVEALYNALEKALQLPVTLLD 448
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y + +V G DA+A V + D + SG G D++ +S KAY+
Sbjct: 449 YRIESVGSGRDALAQVYVKVSLD--------------RKEASGRGTAQDVLEASAKAYIH 494
Query: 540 ALNKM 554
A+N+M
Sbjct: 495 AVNRM 499
[156][TOP]
>UniRef100_Q3SHE7 2-isopropylmalate synthase n=1 Tax=Thiobacillus denitrificans ATCC
25259 RepID=LEU1_THIDA
Length = 511
Score = 116 bits (291), Expect = 1e-24
Identities = 78/186 (41%), Positives = 103/186 (55%), Gaps = 2/186 (1%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNL-FWRFKAVAEQKKRVTDADLIALVSDEVFQPEA 179
KLSGR+A K +L ELG VLD + N F RFK +A++K+ + D DL ALVSDE + E
Sbjct: 330 KLSGRNAFKTKLAELGIVLDSEEALNAAFARFKDLADKKREIFDEDLQALVSDEGYATED 389
Query: 180 V-WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLL 356
+KLL M++ C G + DG E A G+GPVDA +KA++ +V A LL
Sbjct: 390 ERFKLLSMKV-CSETGEVPRAQLVFTDDGAEKQASGEGSGPVDATFKALESVVHSGADLL 448
Query: 357 EYSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYV 536
YS+N +T G DA V + D R +G GA DIVV+S KAY+
Sbjct: 449 LYSVNNITSGTDAQGEVTVRLAQDG--------------RVVNGQGADTDIVVASAKAYL 494
Query: 537 GALNKM 554
ALNK+
Sbjct: 495 HALNKL 500
[157][TOP]
>UniRef100_B8IHS8 2-isopropylmalate synthase n=1 Tax=Methylobacterium nodulans ORS
2060 RepID=LEU1_METNO
Length = 520
Score = 116 bits (291), Expect = 1e-24
Identities = 72/184 (39%), Positives = 102/184 (55%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR A + +L ELGY L D Q + F RFKA+A++KK V D D+ ALV + +
Sbjct: 337 KHSGRAAFRSKLEELGYRLSDNQFQDAFERFKALADRKKNVYDEDIEALVDENLATAHDR 396
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+LL + + GT G +T++L D DG++ + G GPVDA + A+ +V A L Y
Sbjct: 397 IRLLSLTVIAGTRGPQRATMRL-DIDGRQATEEADGNGPVDAVFNAIHALVPHEAKLELY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA A V +R ER+ + GA D +V+S KAY+ A
Sbjct: 456 DVHAVTEGTDAQAEVSVRLR--------------QGERSVTARGADPDTLVASAKAYLAA 501
Query: 543 LNKM 554
LNK+
Sbjct: 502 LNKL 505
[158][TOP]
>UniRef100_C0QPV4 2-isopropylmalate synthase n=1 Tax=Persephonella marina EX-H1
RepID=C0QPV4_PERMH
Length = 514
Score = 116 bits (290), Expect = 1e-24
Identities = 70/184 (38%), Positives = 107/184 (58%), Gaps = 1/184 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYV-LDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEA 179
K SGRHA K RL ELGY L + ++ LF +FKA+A++KK V D D+ AL+ DE+F+
Sbjct: 330 KHSGRHAFKTRLEELGYRNLSEEEVDKLFRKFKALADKKKEVFDEDIEALIFDELFRTYE 389
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
KL+ + G + +STVK+ + DGKE A + G GP+D+A KA++ + L +
Sbjct: 390 EVKLVYFHVLSGNSAIPSSTVKI-EKDGKEITATACGDGPIDSALKAIEKALGMTGRLKD 448
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
YS+ +++ G DA+ R ++ ++ T T SG G DI+ +SVKAY+
Sbjct: 449 YSIRSLSAGKDAMGEVRTVV----DFEGT----------TVSGKGTSTDIIEASVKAYLD 494
Query: 540 ALNK 551
A N+
Sbjct: 495 AYNR 498
[159][TOP]
>UniRef100_B6R018 2-isopropylmalate synthase n=1 Tax=Pseudovibrio sp. JE062
RepID=B6R018_9RHOB
Length = 518
Score = 116 bits (290), Expect = 1e-24
Identities = 73/184 (39%), Positives = 101/184 (54%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA KD+L+ELGY L D L F RFK +A++KK V D D+ ALV D++
Sbjct: 334 KHSGRHAFKDKLSELGYELGDNALQEAFRRFKDLADRKKNVYDEDIEALVEDQITIESES 393
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
K++ + + GT G + + + D +GK + G GPVDA + A+ I AT+ Y
Sbjct: 394 VKVIALTVIAGTGGPQKAILTM-DVNGKHETREATGDGPVDATFNAIKAIWPHDATMSLY 452
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA A V + DN +T G GA D +V+S +AYV A
Sbjct: 453 QVHAVTEGTDAQAEVSVRLE-DNGKIAT-------------GKGADTDTLVASARAYVSA 498
Query: 543 LNKM 554
LNK+
Sbjct: 499 LNKL 502
[160][TOP]
>UniRef100_B5J9E5 2-isopropylmalate synthase n=1 Tax=Octadecabacter antarcticus 307
RepID=B5J9E5_9RHOB
Length = 519
Score = 116 bits (290), Expect = 1e-24
Identities = 72/184 (39%), Positives = 103/184 (55%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+ +L+ELG+ + D +L ++F RFK +A++KK V D DLIALV + + +
Sbjct: 329 KHSGRAALRAKLSELGFEMGDNELKDVFVRFKDLADRKKEVFDDDLIALVRQNSTEDDRL 388
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL D+ + CG G + + L + DG +H + G GPVDA + AV + A L Y
Sbjct: 389 -KLKDLTVVCGMNGPQKADMVL-EIDGSDHSKSATGDGPVDATFNAVKALFAHDARLQLY 446
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + D R +G A D VV+S KAY+ A
Sbjct: 447 QVHAVTEGTDAQATVSVRMEEDG--------------RIATGQSADTDTVVASAKAYINA 492
Query: 543 LNKM 554
LN++
Sbjct: 493 LNRL 496
[161][TOP]
>UniRef100_A6DY52 2-isopropylmalate synthase n=1 Tax=Roseovarius sp. TM1035
RepID=A6DY52_9RHOB
Length = 521
Score = 116 bits (290), Expect = 1e-24
Identities = 73/184 (39%), Positives = 103/184 (55%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+ +L +LGY L D QL+++F RFK +A++KK + D DL+ALV+ V
Sbjct: 333 KHSGRAALRSKLKDLGYELADNQLNDVFVRFKELADRKKEIYDDDLVALVNAGVDPDNNR 392
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++ +++ CGT G +T+ + D DG+E + G GPVDA + AV + A L Y
Sbjct: 393 LQIKHLRVICGTDGPQQATLTM-DIDGREVSTEATGDGPVDATFNAVKALFPHEARLQLY 451
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + E R G A D VV+S KAYV A
Sbjct: 452 QVHAVTEGTDAQATVSVRM--------------EEAGRIVMGQSADTDTVVASAKAYVHA 497
Query: 543 LNKM 554
LN++
Sbjct: 498 LNRL 501
[162][TOP]
>UniRef100_Q3AEQ5 2-isopropylmalate synthase n=1 Tax=Carboxydothermus
hydrogenoformans Z-2901 RepID=LEU1_CARHZ
Length = 509
Score = 116 bits (290), Expect = 1e-24
Identities = 70/184 (38%), Positives = 106/184 (57%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHALK+RL ELGY L + QL+ F +FKA+A++KK VTD DL A++ +E+ +
Sbjct: 329 KHSGRHALKERLLELGYELTEEQLNEAFVKFKALADKKKEVTDQDLEAMMEEEIRKVPET 388
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+ L I+ G+ + T+TV L +G++ + G GPVDA YKA++ I L +Y
Sbjct: 389 YTLDYFHISTGSTIIPTATVGLI-KEGEKLEDAATGDGPVDAIYKAINKITGLTPVLEQY 447
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+NAVT G DA+ V ++ + + +G G DI+ +S KAY+
Sbjct: 448 SINAVTSGEDALGEVVVKLK-------------NGLGKIVTGRGVSTDILEASAKAYLNG 494
Query: 543 LNKM 554
+NK+
Sbjct: 495 INKL 498
[163][TOP]
>UniRef100_Q3A3A9 2-isopropylmalate synthase n=1 Tax=Pelobacter carbinolicus DSM 2380
RepID=Q3A3A9_PELCD
Length = 513
Score = 115 bits (288), Expect = 2e-24
Identities = 70/184 (38%), Positives = 99/184 (53%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA RL ELGY L L F RFKA+A+QKK + D DL A+V+DE+ +
Sbjct: 333 KHSGRHAFGQRLVELGYDLSKEDLDRAFTRFKALADQKKEIFDEDLDAIVADEIIRIPEK 392
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL+ M + G+ +TV + + DG+ A +G GPVDA +K + + A LL +
Sbjct: 393 YKLVQMVTSSGSFAAPIATVAM-EIDGEIKKAAMMGGGPVDATFKTIKKLTDSKADLLSF 451
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++ A+T G DA V + D R G GA DI+V+S KAY+ A
Sbjct: 452 TVGAITGGTDAQGECTVRLELDG--------------REVLGQGAHPDIIVASAKAYINA 497
Query: 543 LNKM 554
LN++
Sbjct: 498 LNRL 501
[164][TOP]
>UniRef100_B5K8F6 2-isopropylmalate synthase n=1 Tax=Octadecabacter antarcticus 238
RepID=B5K8F6_9RHOB
Length = 519
Score = 115 bits (288), Expect = 2e-24
Identities = 72/184 (39%), Positives = 103/184 (55%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+ +L+ LG+ + D +L ++F RFK +A++KK V D DLIALV + + +
Sbjct: 329 KHSGRAALRAKLSVLGFEMGDNELKDVFVRFKDLADRKKEVFDDDLIALVRQNNSEDDRL 388
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL D+ + CG G + + L + DGK+H + G GPVDA + AV + A L Y
Sbjct: 389 -KLKDLTVICGMNGPQKADMVL-EIDGKDHATSATGDGPVDATFNAVKSLFAHDARLQLY 446
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + D R +G A D VV+S KAY+ A
Sbjct: 447 QVHAVTEGTDAQATVSVRMEEDG--------------RIATGQSADTDTVVASAKAYINA 492
Query: 543 LNKM 554
LN++
Sbjct: 493 LNRL 496
[165][TOP]
>UniRef100_B0PBC1 Putative uncharacterized protein n=1 Tax=Anaerotruncus colihominis
DSM 17241 RepID=B0PBC1_9FIRM
Length = 557
Score = 115 bits (288), Expect = 2e-24
Identities = 70/185 (37%), Positives = 104/185 (56%), Gaps = 2/185 (1%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALV-SDEVFQPEA 179
K SG+HA DR+ ELGY + + ++ F RFKA+A++KK +TD D+ AL+ + +
Sbjct: 378 KHSGKHAFADRIAELGYRMSEEDIAEAFERFKALADRKKEITDRDIEALIGASAITDVRE 437
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
V+ L I GT+ +T+ VKL+ DG E + G GP+DAA+ A+D IVK L
Sbjct: 438 VYALKSFVINSGTVISATAVVKLSRDDGTECEHVARGEGPIDAAFNAIDRIVKMDTKLEN 497
Query: 360 YSMNAVTEGIDAIATTRVLIR-GDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYV 536
++M AVTEG DA+ I+ GD+ +G G DI+ SS++AY+
Sbjct: 498 WTMQAVTEGEDALGEAICKIKCGDH---------------IVTGRGLSPDILESSIRAYI 542
Query: 537 GALNK 551
A+NK
Sbjct: 543 NAINK 547
[166][TOP]
>UniRef100_B7KQH6 2-isopropylmalate synthase n=1 Tax=Methylobacterium
chloromethanicum CM4 RepID=B7KQH6_METC4
Length = 520
Score = 115 bits (287), Expect = 3e-24
Identities = 72/184 (39%), Positives = 102/184 (55%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR A K +L ELG L D Q ++F RFKA+A++KK V D D+ ALV ++
Sbjct: 337 KHSGRAAFKSKLGELGISLSDNQFQDVFERFKALADRKKHVYDEDIEALVDEKRATAHDR 396
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL+ + + GT G +T+K+ + DG+ A + G GPVDA + A+ IV A L Y
Sbjct: 397 IKLVSLSVIAGTRGPQRATMKI-EMDGRVFTAEADGNGPVDAVFNAIHEIVPHDAVLELY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA A V ++ ER+ + GA D +V+S KAY+ A
Sbjct: 456 QVHAVTEGTDAQAEVSVRLKAG--------------ERSVTARGADPDTLVASAKAYLSA 501
Query: 543 LNKM 554
LNK+
Sbjct: 502 LNKL 505
[167][TOP]
>UniRef100_B9R0E4 2-isopropylmalate synthase n=1 Tax=Labrenzia alexandrii DFL-11
RepID=B9R0E4_9RHOB
Length = 518
Score = 115 bits (287), Expect = 3e-24
Identities = 71/184 (38%), Positives = 100/184 (54%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA +D+L ELG+ L D L + F RFK +A++KK V D D+ ALV DE+
Sbjct: 335 KHSGRHAFRDKLRELGFELGDNALQDAFRRFKDLADRKKHVYDEDIEALVEDEINILGES 394
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
K++ + + GT G + + + D DG+ + G GPVDA + A+ I ATL Y
Sbjct: 395 TKVIALTVIAGTGGPQKAILTM-DVDGQHVTKEATGDGPVDATFNAIKAISPHEATLSLY 453
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA A V + D R +G GA D +V+S +AYV A
Sbjct: 454 QVHAVTEGTDAQAEVSVRLEADG--------------RIATGKGADTDTLVASARAYVSA 499
Query: 543 LNKM 554
+NK+
Sbjct: 500 MNKL 503
[168][TOP]
>UniRef100_B6AXP6 2-isopropylmalate synthase n=1 Tax=Rhodobacterales bacterium
HTCC2083 RepID=B6AXP6_9RHOB
Length = 529
Score = 115 bits (287), Expect = 3e-24
Identities = 70/184 (38%), Positives = 100/184 (54%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+ +L LG+ L D QL ++F RFK +A++KK + D DL+AL++
Sbjct: 339 KHSGRAALRSKLENLGFELGDNQLKDVFVRFKELADRKKEIFDDDLVALMNTASDPESER 398
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL +++ CGT G + +++ DG E + G GPVDA + AV + A L Y
Sbjct: 399 LKLTSLRVVCGTDGPQEAVMRML-VDGVEKSTTATGDGPVDATFNAVKALFAHEARLQLY 457
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + E RT +G A D VV+S KAY+ A
Sbjct: 458 QVHAVTEGTDAQATVSVRL--------------EEEGRTVTGQSADTDTVVASAKAYISA 503
Query: 543 LNKM 554
LN++
Sbjct: 504 LNRL 507
[169][TOP]
>UniRef100_A3VYC0 2-isopropylmalate synthase n=1 Tax=Roseovarius sp. 217
RepID=A3VYC0_9RHOB
Length = 530
Score = 115 bits (287), Expect = 3e-24
Identities = 72/184 (39%), Positives = 103/184 (55%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+ +L +LGY L D QL+++F RFK +A++KK + D DL+ALV+ V
Sbjct: 342 KHSGRAALRSKLKDLGYELADNQLNDVFVRFKELADRKKEIYDDDLVALVNAGVDSENNR 401
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++ +++ CGT G +T+ + + DG+E + G GPVDA + AV + A L Y
Sbjct: 402 LQIKHLRVICGTDGPQQATLTM-EIDGREVSTEATGDGPVDATFNAVKALFPHEARLQLY 460
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + E R G A D VV+S KAYV A
Sbjct: 461 QVHAVTEGTDAQATVSVRM--------------EEAGRIVMGQSADTDTVVASAKAYVHA 506
Query: 543 LNKM 554
LN++
Sbjct: 507 LNRL 510
[170][TOP]
>UniRef100_Q16AY3 2-isopropylmalate synthase n=1 Tax=Roseobacter denitrificans OCh
114 RepID=Q16AY3_ROSDO
Length = 522
Score = 114 bits (286), Expect = 4e-24
Identities = 71/184 (38%), Positives = 101/184 (54%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+ +L LG+ L D QL ++F RFKA+A++KK + D DLIAL+
Sbjct: 334 KHSGRAALRSKLENLGFELGDNQLKDVFVRFKALADRKKEIYDDDLIALMRTATDPENDR 393
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL+ +++ CGT G + + L + DG E G GPVDA++ A+ +V A L Y
Sbjct: 394 IKLVSLRVVCGTHGPQQADLVL-NIDGVEKSTTQTGDGPVDASFNAIKALVSHSARLQLY 452
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + E R +G A D VV+S +AY+ A
Sbjct: 453 QVHAVTEGTDAQATVSVRM--------------EEEGRIVTGQSADTDTVVASARAYIHA 498
Query: 543 LNKM 554
LN++
Sbjct: 499 LNRL 502
[171][TOP]
>UniRef100_A9W659 2-isopropylmalate synthase n=1 Tax=Methylobacterium extorquens PA1
RepID=A9W659_METEP
Length = 520
Score = 114 bits (286), Expect = 4e-24
Identities = 72/184 (39%), Positives = 102/184 (55%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR A K +L ELG L D Q ++F RFKA+A++KK V D D+ ALV ++
Sbjct: 337 KHSGRAAFKSKLGELGISLSDNQFQDVFERFKALADRKKHVYDEDIEALVDEKRATAHDR 396
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL+ + + GT G +T+K+ + DG+ A + G GPVDA + A+ IV A L Y
Sbjct: 397 IKLVSLSVIAGTRGPQRATMKI-EMDGRIFTAEADGNGPVDAVFNAIHEIVPHDAVLELY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA A V ++ ER+ + GA D +V+S KAY+ A
Sbjct: 456 QVHAVTEGTDAQAEVSVRLKAG--------------ERSVTARGADPDTLVASAKAYLSA 501
Query: 543 LNKM 554
LNK+
Sbjct: 502 LNKL 505
[172][TOP]
>UniRef100_C8WI89 2-isopropylmalate synthase n=1 Tax=Eggerthella lenta DSM 2243
RepID=C8WI89_9ACTN
Length = 510
Score = 114 bits (286), Expect = 4e-24
Identities = 68/182 (37%), Positives = 102/182 (56%)
Frame = +3
Query: 9 SGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWK 188
SG ALK RL ELGY L+ L ++ F +A++KK V D DL +LV++ A++
Sbjct: 333 SGHAALKHRLEELGYELEGEALDQVYEAFLNLADKKKEVYDEDLESLVNERDRNESALYA 392
Query: 189 LLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSM 368
L +Q++ G T+TV L ++ + AC GTGP+DA YKAV+ IV+ L E+S+
Sbjct: 393 LEGVQVSTGFPLTPTATVTLRNAADQVVTACEYGTGPIDAVYKAVNKIVQVDNELTEFSV 452
Query: 369 NAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGALN 548
+VT GIDA+ + + + ++G GA DI+VSS KAY+ ALN
Sbjct: 453 QSVTRGIDALGEVTIRVTAPDG-------------GVYTGRGADNDIIVSSTKAYLNALN 499
Query: 549 KM 554
++
Sbjct: 500 RL 501
[173][TOP]
>UniRef100_C7C7H0 2-isopropylmalate synthase n=2 Tax=Methylobacterium extorquens
RepID=C7C7H0_METED
Length = 520
Score = 114 bits (286), Expect = 4e-24
Identities = 72/184 (39%), Positives = 102/184 (55%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR A K +L ELG L D Q ++F RFKA+A++KK V D D+ ALV ++
Sbjct: 337 KHSGRAAFKSKLGELGISLSDNQFQDVFERFKALADRKKHVYDEDIEALVDEKRATAHDR 396
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL+ + + GT G +T+K+ + DG+ A + G GPVDA + A+ IV A L Y
Sbjct: 397 IKLVSLSVIAGTRGPQRATMKI-EMDGRIFTAEADGNGPVDAVFNAIHEIVPHDAVLELY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA A V ++ ER+ + GA D +V+S KAY+ A
Sbjct: 456 QVHAVTEGTDAQAEVSVRLKAG--------------ERSVTARGADPDTLVASAKAYLSA 501
Query: 543 LNKM 554
LNK+
Sbjct: 502 LNKL 505
[174][TOP]
>UniRef100_A9DV85 2-isopropylmalate synthase n=1 Tax=Oceanibulbus indolifex HEL-45
RepID=A9DV85_9RHOB
Length = 522
Score = 114 bits (286), Expect = 4e-24
Identities = 71/184 (38%), Positives = 102/184 (55%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+ +L +LG+ L D QL ++F RFK +A++KK + + DLIAL+ E
Sbjct: 334 KHSGRAALRSKLEDLGFELGDNQLKDVFVRFKELADRKKEIYEDDLIALMRTATDPEEDR 393
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+L +++ CGT G T+ + L + DG E G GPVDAA+ + +V A L Y
Sbjct: 394 IRLKSLKVVCGTEGPQTADMVL-EVDGAEQSTNQTGDGPVDAAFNCIKALVLHTARLQLY 452
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + E R +G A D VV+SV+AY+ A
Sbjct: 453 QVHAVTEGTDAQATVSVRM--------------EEEGRIVTGQSADTDTVVASVRAYIHA 498
Query: 543 LNKM 554
LN++
Sbjct: 499 LNRL 502
[175][TOP]
>UniRef100_A4U0T7 2-isopropylmalate synthase n=1 Tax=Magnetospirillum gryphiswaldense
RepID=A4U0T7_9PROT
Length = 514
Score = 114 bits (286), Expect = 4e-24
Identities = 68/184 (36%), Positives = 98/184 (53%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR A KD+L +LGY L D + + F RFK VA++KK V D D++ALV + VF+
Sbjct: 331 KHSGRAAFKDKLKQLGYDLGDNAIEDAFARFKDVADRKKEVFDEDIVALVDEAVFRDNER 390
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+ +++ CGT + DG+ + G GPVDA + A+ + A LL Y
Sbjct: 391 IRFKGLEVLCGTRHNPPKAELELEIDGELKSVKATGDGPVDATFNAIKALCPHEARLLLY 450
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVT+G DA A V + D +T +G GA D +V+S +AYV A
Sbjct: 451 QVHAVTQGTDAQAEVTVRLEEDG--------------KTVNGQGADTDTMVASARAYVKA 496
Query: 543 LNKM 554
LNK+
Sbjct: 497 LNKL 500
[176][TOP]
>UniRef100_B6JB87 2-isopropylmalate synthase n=1 Tax=Oligotropha carboxidovorans OM5
RepID=LEU1_OLICO
Length = 519
Score = 114 bits (286), Expect = 4e-24
Identities = 71/184 (38%), Positives = 102/184 (55%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA + +L ELGY L D QL + F RFKA+A++KK + D D+ ALV E+ Q
Sbjct: 337 KHSGRHAFQHKLRELGYELADNQLQDAFVRFKALADRKKDIYDEDIEALVDQELAQTHDR 396
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+L+ + + GT G +T+K+ + DGK + + G GPVDA + AV +V A L Y
Sbjct: 397 LRLVSLTVIAGTHGPQRATMKV-EVDGKVRIDEAEGNGPVDAVFNAVKTLVPHEAKLELY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVT G DA A V + D R+ + + D +V+S KAY+ A
Sbjct: 456 QVHAVTAGTDAQAEVSVRLSQDG--------------RSVTARSSDPDTLVASAKAYLSA 501
Query: 543 LNKM 554
LNK+
Sbjct: 502 LNKI 505
[177][TOP]
>UniRef100_Q3SQ49 2-isopropylmalate synthase n=1 Tax=Nitrobacter winogradskyi Nb-255
RepID=LEU1_NITWN
Length = 519
Score = 114 bits (286), Expect = 4e-24
Identities = 71/184 (38%), Positives = 101/184 (54%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA + +L ELGY L + QL + F RFKA+A++KK + D D+IALV +E+
Sbjct: 337 KHSGRHAFQHKLEELGYKLAENQLQDAFVRFKALADRKKDIYDEDIIALVDEEMAATHDR 396
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL + + GT G +T+KL S G+ + + G GPVDA + + +V A L Y
Sbjct: 397 IKLSSLTVIAGTHGPQRATMKLTVS-GQTRIEEAEGNGPVDAVFNCIKRLVPHEAKLELY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVT+G DA A V + D R + A D +V+S KAY+GA
Sbjct: 456 QVHAVTQGTDAQAEVSVRLSQDG--------------RAMTSKAADPDTLVASAKAYLGA 501
Query: 543 LNKM 554
LNK+
Sbjct: 502 LNKI 505
[178][TOP]
>UniRef100_Q1QJV3 2-isopropylmalate synthase n=1 Tax=Nitrobacter hamburgensis X14
RepID=LEU1_NITHX
Length = 520
Score = 114 bits (286), Expect = 4e-24
Identities = 70/184 (38%), Positives = 100/184 (54%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA + +L ELGY L + QL + F RFKA+A++KK + D D++ALV +E+
Sbjct: 337 KHSGRHAFQHKLEELGYKLAENQLQDAFVRFKALADRKKDIYDEDIVALVDEEMAASHDR 396
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL + + GT G +T+KL DG+ + + G GPVDA + + +V A L Y
Sbjct: 397 IKLTSLTVIAGTHGPQRATMKLT-VDGQTRIEEAEGNGPVDAVFNCIKRLVPHEAKLDLY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVT G DA A V + D R + A D +V+S KAY+GA
Sbjct: 456 QVHAVTHGTDAQAEVSVRLSQDG--------------RAMTSKAADPDTLVASAKAYLGA 501
Query: 543 LNKM 554
LNK+
Sbjct: 502 LNKI 505
[179][TOP]
>UniRef100_A4IRH8 2-isopropylmalate synthase n=2 Tax=Geobacillus RepID=LEU1_GEOTN
Length = 515
Score = 114 bits (286), Expect = 4e-24
Identities = 69/185 (37%), Positives = 106/185 (57%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQP-EA 179
K SGRHAL++R+ ELGY L + +++ LF RFK +A++KK VTD DLIAL+ +E F +
Sbjct: 329 KHSGRHALRNRVEELGYTLSEEEINQLFVRFKELADKKKDVTDDDLIALIFEEKFDHFKD 388
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++L +Q+ GT + T+ V L D G + G G V+A Y ++ + TLL+
Sbjct: 389 FYQLSSIQVQYGTNQIPTAVVVLKDGKGNTIQEAATGAGSVEALYNTLERCFQTAVTLLD 448
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y + +V G DA+A V +R ++ VE SG G D++ +S KAY+
Sbjct: 449 YRIESVGGGRDALAQVFVKVRVND------------VET--SGRGTAQDVLEASAKAYIN 494
Query: 540 ALNKM 554
A+N+M
Sbjct: 495 AMNRM 499
[180][TOP]
>UniRef100_C0R089 2-isopropylmalate synthase n=1 Tax=Brachyspira hyodysenteriae WA1
RepID=C0R089_BRAHW
Length = 498
Score = 114 bits (285), Expect = 5e-24
Identities = 66/184 (35%), Positives = 97/184 (52%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SG+HA KDR+ LGY +DD L + F FKA+A++KK VTD+D+ AL+ +
Sbjct: 329 KHSGKHAFKDRIESLGYDIDDKALEDKFIEFKALADKKKIVTDSDIEALLIGNNDSDNPI 388
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+ L + G S +TV + D+ G GP+DAA+ A+D I A L+ Y
Sbjct: 389 YTLNGFVVNDGNSISSLATVSIMDNQNNVVEGIGKGNGPIDAAFGAIDSITSNKAKLVNY 448
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+NA+TEG DA+ V + D ++T G DI+ +S++AYV
Sbjct: 449 SINAITEGEDALGEVIVKLASD--------------DKTVIGRAVSTDIIEASLRAYVNG 494
Query: 543 LNKM 554
LNK+
Sbjct: 495 LNKL 498
[181][TOP]
>UniRef100_C7ILY9 2-isopropylmalate synthase n=1 Tax=Clostridium papyrosolvens DSM
2782 RepID=C7ILY9_9CLOT
Length = 508
Score = 114 bits (285), Expect = 5e-24
Identities = 69/183 (37%), Positives = 102/183 (55%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSG HA ++RL E+GY L D ++ F +FK +A++KK VTD D+ ALV + + PE +
Sbjct: 330 KLSGHHAFEERLKEMGYSLSDEEVKTAFAKFKDLADKKKVVTDKDIEALVDENIAVPE-I 388
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+ + QI G +STSTV + D + + G GPVDAA+ A++ A L+ Y
Sbjct: 389 FVIDSFQINSGNKMISTSTVSI-KKDEEIITEAATGDGPVDAAFNAIERATGVNAELVHY 447
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
+ AVTEG DA+ V I +++ F G G DI+ +SVKAY+ A
Sbjct: 448 RIKAVTEGKDALGEVTVKISHNDS--------------VFMGKGVSTDIIEASVKAYLNA 493
Query: 543 LNK 551
+N+
Sbjct: 494 INR 496
[182][TOP]
>UniRef100_A3WU66 2-isopropylmalate synthase n=1 Tax=Nitrobacter sp. Nb-311A
RepID=A3WU66_9BRAD
Length = 519
Score = 114 bits (285), Expect = 5e-24
Identities = 71/184 (38%), Positives = 101/184 (54%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA + +L ELGY L + QL + F RFKA+A++KK + D D+IALV +E+
Sbjct: 337 KHSGRHAFQHKLEELGYRLAENQLQDAFVRFKALADRKKDIYDEDIIALVDEEMAATHDR 396
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL + + GT G +T+KL S G+ + + G GPVDA + + +V A L Y
Sbjct: 397 IKLSSLTVIAGTHGPQRATMKLTIS-GQTRIEEAEGNGPVDAVFNCIKRLVPHEAKLELY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVT+G DA A V + D R + A D +V+S KAY+GA
Sbjct: 456 QVHAVTQGTDAQAEVSVRLSQDG--------------RAMTSKAADPDTLVASAKAYLGA 501
Query: 543 LNKM 554
LNK+
Sbjct: 502 LNKI 505
[183][TOP]
>UniRef100_Q2W1F9 Isopropylmalate/homocitrate/citramalate synthase n=1
Tax=Magnetospirillum magneticum AMB-1 RepID=Q2W1F9_MAGSA
Length = 544
Score = 114 bits (284), Expect = 6e-24
Identities = 69/184 (37%), Positives = 97/184 (52%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR A K +L ELGY L D + + F RFK +A++KK V D D++ALV D V +
Sbjct: 361 KHSGRAAFKAKLKELGYELGDNAIEDAFTRFKDLADRKKDVFDEDIVALVDDAVVRGNDR 420
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL+ +++ CGT S DG+ + G GPVDA + A+ + A L Y
Sbjct: 421 VKLVSLEVLCGTKHQPPSATLELSVDGEVKGVRATGDGPVDATFNAIKALFPHEARLQLY 480
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVT+G DA A V + D +T +G GA D +V+S +AYV A
Sbjct: 481 QVSAVTQGTDAQAEVTVRLEEDG--------------KTVNGQGAETDTLVASARAYVNA 526
Query: 543 LNKM 554
LNK+
Sbjct: 527 LNKL 530
[184][TOP]
>UniRef100_A4EEV9 2-isopropylmalate synthase n=1 Tax=Roseobacter sp. CCS2
RepID=A4EEV9_9RHOB
Length = 519
Score = 114 bits (284), Expect = 6e-24
Identities = 73/184 (39%), Positives = 105/184 (57%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+ +LNELG+ L D QL+++F RFK +A++KK V D DL+ALV+ + + +
Sbjct: 331 KHSGRAALRAKLNELGFDLADNQLNDVFVRFKDLADRKKEVFDDDLMALVTQNDAEDDRL 390
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL +++ CGT G + + + + DG + + G GPVDA + AV I A L Y
Sbjct: 391 -KLKSLRVVCGTDGPQKADM-VMEVDGADVETSATGDGPVDATFNAVKAIFSHGARLQIY 448
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + E R +G A D VV+S KAY+ A
Sbjct: 449 QVSAVTEGTDAQATVSVRM--------------EEEGRIATGQSADTDTVVASAKAYINA 494
Query: 543 LNKM 554
LN++
Sbjct: 495 LNRL 498
[185][TOP]
>UniRef100_A5D4W0 2-isopropylmalate synthase n=1 Tax=Pelotomaculum thermopropionicum
SI RepID=LEU1_PELTS
Length = 505
Score = 114 bits (284), Expect = 6e-24
Identities = 69/185 (37%), Positives = 101/185 (54%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA + RL E+GY L D +L++ F RFK +A++K +TD DL A++ +E+
Sbjct: 330 KHSGRHAFRHRLEEMGYNLSDEELNSAFERFKKLADKKMEITDEDLEAIIEEEMRLVPHT 389
Query: 183 WKLLDMQITCGTLGLSTSTVKL-ADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
+ L + I+ GT + T+TV L D E AC G GPVDA KA+D I T+
Sbjct: 390 YTLEYLHISSGTTVVPTATVGLKRDGQLMEEAAC--GNGPVDAICKAIDKITGLNCTMTS 447
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
+ +NAVT G DA+ + + D E+ + G G D++ +S KAYV
Sbjct: 448 WGINAVTAGKDALGDVSLKVTADG-------------EKVYVGRGISTDVLEASAKAYVN 494
Query: 540 ALNKM 554
A+NK+
Sbjct: 495 AVNKL 499
[186][TOP]
>UniRef100_A4YZ76 2-isopropylmalate synthase n=1 Tax=Bradyrhizobium sp. ORS278
RepID=LEU1_BRASO
Length = 525
Score = 114 bits (284), Expect = 6e-24
Identities = 69/184 (37%), Positives = 100/184 (54%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA +L E+G+ L Q+ + F RFKA+A++KK++ D D+ AL+ + +
Sbjct: 337 KHSGRHAFIHKLEEMGHKLSSNQVEDAFVRFKALADRKKQIYDEDIEALIDEGMVSAHDR 396
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KLL + + GT G +T+KL D DG + S G GPVDA + + +V A L Y
Sbjct: 397 IKLLSLSVIAGTRGPQRATMKL-DIDGVTRIEESEGNGPVDAVFNCIKSLVPHEAKLELY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA A V + D R+ + A D +V+S KAY+GA
Sbjct: 456 QVHAVTEGTDAQAEVSVRLSQDG--------------RSMTARAADPDTLVASAKAYLGA 501
Query: 543 LNKM 554
LNK+
Sbjct: 502 LNKL 505
[187][TOP]
>UniRef100_Q0AV20 2-isopropylmalate synthase n=1 Tax=Syntrophomonas wolfei subsp.
wolfei str. Goettingen RepID=Q0AV20_SYNWW
Length = 509
Score = 113 bits (283), Expect = 8e-24
Identities = 76/185 (41%), Positives = 104/185 (56%), Gaps = 2/185 (1%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA K+RL ELGY L D +L F FK +A++KK VT+ DL ALV D+V+
Sbjct: 332 KHSGRHAFKERLEELGYRLGDEELEKAFLDFKELADKKKEVTNDDLEALVKDKVWAIPER 391
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+ L +QI GT + T+TVKLA + A S G GPVDAA AVD I + E+
Sbjct: 392 FTLNYLQICSGTSIVPTATVKLA-IEKMVFEAASTGDGPVDAACHAVDKITDIYGKMHEF 450
Query: 363 SMNAVTEGIDAI--ATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYV 536
+NAV+ G DA+ +R+ I G + ++G G DI+ +SVK+Y+
Sbjct: 451 KINAVSSGKDALGEVISRIEIGG----------------KIYNGRGLSTDIIEASVKSYI 494
Query: 537 GALNK 551
A+NK
Sbjct: 495 NAINK 499
[188][TOP]
>UniRef100_C6XN10 2-isopropylmalate synthase n=1 Tax=Hirschia baltica ATCC 49814
RepID=C6XN10_HIRBI
Length = 513
Score = 113 bits (283), Expect = 8e-24
Identities = 67/184 (36%), Positives = 107/184 (58%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR+A +D+L LGYVLDD +++ F RFK +A++KK V D D++ALV D++ + +
Sbjct: 333 KLSGRNAFRDKLENLGYVLDDEAMNDAFRRFKDLADKKKDVFDEDIMALVDDQLSGTDEL 392
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
L +++ GT G + ++L +++G+ A + G GPVDA + A+ I+ A L +
Sbjct: 393 ISLHALKVVAGTEGPQIAEIEL-ETEGEIKSARAEGNGPVDAVFNAIRAIIPHDAVLELF 451
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + D + +G + D +VS+ KAY+ A
Sbjct: 452 QIHAVTEGTDAQATVSVRLSEDGLVA--------------TGKSSDPDTLVSAAKAYIHA 497
Query: 543 LNKM 554
NK+
Sbjct: 498 FNKL 501
[189][TOP]
>UniRef100_A1B9A2 2-isopropylmalate synthase n=1 Tax=Paracoccus denitrificans PD1222
RepID=A1B9A2_PARDP
Length = 520
Score = 113 bits (283), Expect = 8e-24
Identities = 74/185 (40%), Positives = 102/185 (55%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPE-A 179
K SGR AL+ +L +LGY L D QL ++F RFKA+A++KK V D DL+ALV D E
Sbjct: 331 KHSGRAALRAKLKDLGYELGDNQLKDVFIRFKALADRKKEVYDDDLVALVQDAATNTEDD 390
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++ +++ CG+ G S L G+E + G GPVDA + AV I A L
Sbjct: 391 HLQVKHLRVVCGSDGQSADLTMLV--GGEEQTVHAEGDGPVDACFNAVKAIWPHRARLQL 448
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y ++AVTEG DA AT V + E R +G + D +++SVKAYVG
Sbjct: 449 YQVHAVTEGTDAQATVSVRM--------------EEEGRIATGQASDTDTILASVKAYVG 494
Query: 540 ALNKM 554
ALN++
Sbjct: 495 ALNRL 499
[190][TOP]
>UniRef100_Q0FMQ1 2-isopropylmalate synthase n=1 Tax=Roseovarius sp. HTCC2601
RepID=Q0FMQ1_9RHOB
Length = 521
Score = 113 bits (283), Expect = 8e-24
Identities = 70/184 (38%), Positives = 105/184 (57%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+ +L ELG + D QL ++F RFK +A++KK V D D++ALV+ +
Sbjct: 333 KHSGRAALRAKLKELGTEVGDNQLKDIFVRFKDLADRKKEVYDEDILALVTAAMTDGADH 392
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+++ +++TCGT G + +T+++ + G+E A G GPVDA +KAV + A L Y
Sbjct: 393 LEIVSLKVTCGTGGPAEATLEM-EVGGEEMSATEHGDGPVDATFKAVRALYPNKARLQLY 451
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + D + +G A D V +S KAYV A
Sbjct: 452 QVHAVTEGTDAQATVSVRLEEDGKIA--------------TGQSADTDTVYASAKAYVNA 497
Query: 543 LNKM 554
LN++
Sbjct: 498 LNRL 501
[191][TOP]
>UniRef100_A1HLS3 2-isopropylmalate synthase n=1 Tax=Thermosinus carboxydivorans Nor1
RepID=A1HLS3_9FIRM
Length = 515
Score = 113 bits (283), Expect = 8e-24
Identities = 69/184 (37%), Positives = 104/184 (56%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA + RL +LGY L++ ++ LF RFK +A++KK V D D+ AL++++
Sbjct: 331 KHSGRHAFEQRLRQLGYELEEKAVTELFARFKDLADRKKIVFDRDIEALIANKASGQPEW 390
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L+ + G L+T++V+LA S G A + G GPVDA +KA++ V L ++
Sbjct: 391 YQLVYHHVVSGNQTLATASVRLA-SSGAVSEAAACGDGPVDATFKAIEKAVGFSIGLKDF 449
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
+ AVT G DA+ V + E RTFSG G DI+ +S +AYV A
Sbjct: 450 QLKAVTAGEDALGEATVWV--------------EREGRTFSGRGLSTDIIEASARAYVNA 495
Query: 543 LNKM 554
+NKM
Sbjct: 496 INKM 499
[192][TOP]
>UniRef100_Q49Z12 2-isopropylmalate synthase n=1 Tax=Staphylococcus saprophyticus
subsp. saprophyticus ATCC 15305 RepID=LEU1_STAS1
Length = 511
Score = 113 bits (283), Expect = 8e-24
Identities = 65/180 (36%), Positives = 101/180 (56%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSG+HA ++L LGY +D + LF +FK VA++KK VTD D+ AL+ + A+
Sbjct: 330 KLSGKHAFAEKLTALGYDVDPEEQKTLFKQFKTVADKKKAVTDRDIHALIQGTEHEQNAI 389
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+K+ +Q+ + GL ++ V + D DG + S+GTG + + Y AVD I L+EY
Sbjct: 390 YKVETLQLQFVSNGLQSAVVVIKDIDGNTYQDSSIGTGSIVSVYNAVDRIFDRKTELIEY 449
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
+++VTEG DA A V I+ D ++ +G G DI+++S K+YV A
Sbjct: 450 RIDSVTEGTDAQAEVHVQIKID--------------DQIVTGVGIDHDILLASCKSYVEA 495
[193][TOP]
>UniRef100_Q212A9 2-isopropylmalate synthase n=1 Tax=Rhodopseudomonas palustris
BisB18 RepID=LEU1_RHOPB
Length = 521
Score = 113 bits (283), Expect = 8e-24
Identities = 69/184 (37%), Positives = 100/184 (54%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA +L E+GY L QL + F RFKA+A++KK + D D+ ALV E+ Q
Sbjct: 337 KHSGRHAFVHKLEEMGYKLGQNQLEDAFVRFKALADRKKEIYDEDIEALVDQEIAQSHDR 396
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KLL + + GT G +T+KL D +G+ + + G GPVDA + + +V A L Y
Sbjct: 397 IKLLSLTVIAGTHGPQRATMKL-DVEGQTRIEEAEGNGPVDAVFNCIKALVPHVAKLELY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVT+G DA A V + + R+ + A D +V+S KAY+ A
Sbjct: 456 QVHAVTQGTDAQAEVSVRLAHEG--------------RSMTARAADPDTLVASAKAYLSA 501
Query: 543 LNKM 554
LNK+
Sbjct: 502 LNKI 505
[194][TOP]
>UniRef100_A3SVG7 2-Isopropylmalate synthase n=1 Tax=Sulfitobacter sp. NAS-14.1
RepID=A3SVG7_9RHOB
Length = 523
Score = 113 bits (282), Expect = 1e-23
Identities = 71/184 (38%), Positives = 98/184 (53%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+ +L LGY L D QL ++F RFK +A++KK + D DLIAL+
Sbjct: 334 KHSGRAALRSKLENLGYELGDNQLKDVFVRFKELADRKKEIYDDDLIALMRTATDPESDR 393
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
L M + CGT G + + L+ DG E G GPVDA++ + +V+ A L Y
Sbjct: 394 IVLNSMTVVCGTEGPQKAEMSLS-VDGTETSTSQTGDGPVDASFNCIKALVEHTARLQLY 452
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + D R +G A D VV+SV+AY+ A
Sbjct: 453 QVHAVTEGTDAQATVSVRLEEDG--------------RIVTGQSADTDTVVASVRAYIHA 498
Query: 543 LNKM 554
LN++
Sbjct: 499 LNRL 502
[195][TOP]
>UniRef100_B1ZDN3 2-isopropylmalate synthase n=1 Tax=Methylobacterium populi BJ001
RepID=LEU1_METPB
Length = 520
Score = 113 bits (282), Expect = 1e-23
Identities = 71/184 (38%), Positives = 101/184 (54%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR A K +L ELG L D Q ++F RFK +A++KK V D D+ ALV +++
Sbjct: 337 KHSGRAAFKSKLAELGISLSDNQFQDVFERFKDLADRKKHVYDEDIEALVDEKLATAHDR 396
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KLL + + GT G +T+K+ + DG+ + G GPVDA + A+ IV A L Y
Sbjct: 397 IKLLSLSVIAGTRGPQRATMKI-EMDGRTFTEEADGNGPVDAVFNAIHEIVPHDAVLELY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA A V ++ ER+ + GA D +V+S KAY+ A
Sbjct: 456 QVHAVTEGTDAQAEVSVRLKAG--------------ERSVTARGADPDTLVASAKAYLSA 501
Query: 543 LNKM 554
LNK+
Sbjct: 502 LNKL 505
[196][TOP]
>UniRef100_B1I1Y1 2-isopropylmalate synthase n=1 Tax=Candidatus Desulforudis
audaxviator MP104C RepID=LEU1_DESAP
Length = 509
Score = 113 bits (282), Expect = 1e-23
Identities = 65/185 (35%), Positives = 104/185 (56%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA + RL ELG+ L + +L+ F RFK +A+ KK++TD DL A++ + + Q A
Sbjct: 330 KHSGRHAFRQRLTELGFELHEEELNRAFVRFKELADSKKQITDEDLEAILDETIRQVPAT 389
Query: 183 WKLLDMQITCGTLGLSTSTV-KLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++L + + GT T+ + L D + AC G GPVDA YKA++ +L+
Sbjct: 390 YELDYLHVFSGTTVKPTAVIGLLIDGQFVQEAAC--GNGPVDATYKAIEKATGRKYSLVS 447
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y ++AVT G DA+A + +R D++ R ++G G D++ +S +AYV
Sbjct: 448 YVIDAVTGGTDALANVTLKMRDDDH-------------RVYTGRGVSADVLEASARAYVN 494
Query: 540 ALNKM 554
+NK+
Sbjct: 495 IMNKI 499
[197][TOP]
>UniRef100_A9BGP5 2-isopropylmalate synthase n=1 Tax=Petrotoga mobilis SJ95
RepID=A9BGP5_PETMO
Length = 510
Score = 112 bits (281), Expect = 1e-23
Identities = 73/186 (39%), Positives = 107/186 (57%), Gaps = 3/186 (1%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHALK+ L GY +++ LF +FK +A +KK + D+ AL++DE+++ E
Sbjct: 330 KHSGRHALKEFLTSSGYTVNEETFEKLFIKFKDLASKKKNLNPLDVEALINDELYKTEDY 389
Query: 183 WKLLDMQITCGTLGLSTSTVKLA-DSDGKEHVACSVGTGPVDAAYKAVDLIVKEP-ATLL 356
+KL + +T G L T+T+K+A D E ACS G GP+DA +KA++ I +E TL+
Sbjct: 390 FKLKYLSVTTGNTTLPTATIKIARGEDLIEKAACS-GDGPIDAIFKAINEIAEEENITLI 448
Query: 357 EYSMNAVTEGIDAIATTRVLIR-GDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAY 533
Y + VTEG DA+ T V ++ G++ Y G SVE DI +S AY
Sbjct: 449 SYKIEGVTEGTDALGETTVKLKIGEDVY------VGHSVE---------TDITQASTLAY 493
Query: 534 VGALNK 551
+ ALNK
Sbjct: 494 LNALNK 499
[198][TOP]
>UniRef100_C7RNH2 2-isopropylmalate synthase n=1 Tax=Candidatus Accumulibacter
phosphatis clade IIA str. UW-1 RepID=C7RNH2_9PROT
Length = 512
Score = 112 bits (281), Expect = 1e-23
Identities = 74/186 (39%), Positives = 100/186 (53%), Gaps = 2/186 (1%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQ-LSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEA 179
K SGR+A K RL+ LG VL+ + L+ F RFK +A++K + D DL ALVSDE P
Sbjct: 330 KHSGRNAFKSRLSALGIVLESEESLNAAFARFKELADKKHEIFDEDLQALVSDEEIAPAN 389
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
+ L C G + + + G E A +G+GPVDA +KA++ I + A LL
Sbjct: 390 EYYKLVYSHVCSETGETPAANVTLTAGGVEKSASGIGSGPVDATFKAIECIAESGAQLLL 449
Query: 360 YSMNAVTEGIDAIATTRV-LIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYV 536
YS+NA+T G DA V L RG R +G GA DIV++S KAY+
Sbjct: 450 YSVNAITTGTDAQGEVTVRLARGG---------------RIVNGNGADTDIVIASAKAYL 494
Query: 537 GALNKM 554
ALNK+
Sbjct: 495 NALNKL 500
[199][TOP]
>UniRef100_A3SGB0 2-Isopropylmalate synthase n=1 Tax=Sulfitobacter sp. EE-36
RepID=A3SGB0_9RHOB
Length = 523
Score = 112 bits (281), Expect = 1e-23
Identities = 72/184 (39%), Positives = 96/184 (52%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+ +L LGY L D QL ++F RFK +A++KK + D DLIAL+
Sbjct: 334 KHSGRAALRSKLENLGYELGDNQLKDVFVRFKELADRKKEIYDDDLIALMRTATDPESDR 393
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
L M + CGT G + + L DG E G GPVDAA+ + +V A L Y
Sbjct: 394 IVLGSMTVVCGTEGPQKAEMSLT-VDGAETSTSQTGDGPVDAAFNCIKALVDHSARLQLY 452
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + D R +G A D VV+SV+AY+ A
Sbjct: 453 QVHAVTEGTDAQATVSVRLEEDG--------------RIVTGQSADTDTVVASVRAYIHA 498
Query: 543 LNKM 554
LN++
Sbjct: 499 LNRL 502
[200][TOP]
>UniRef100_Q07PI3 2-isopropylmalate synthase n=1 Tax=Rhodopseudomonas palustris
BisA53 RepID=LEU1_RHOP5
Length = 521
Score = 112 bits (281), Expect = 1e-23
Identities = 70/184 (38%), Positives = 101/184 (54%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA +L E+GY L QL + F RFKA+A++KK + D D+ ALV E+ Q
Sbjct: 337 KHSGRHAFIHKLEEMGYKLGQNQLEDAFVRFKALADRKKDIYDEDIEALVDLEIAQSHDR 396
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL+ + + GT G +T+KL D DG+ + + G GPVDA + + +V A L Y
Sbjct: 397 IKLVSLTVIAGTHGPQRATMKL-DVDGQTKIEEAEGNGPVDAVFNCIKALVPHVAKLELY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA A V + + R+ + + D +V+S KAY+GA
Sbjct: 456 QVHAVTEGTDAQAEVSVRLSHEG--------------RSVTSRASDPDTLVASAKAYLGA 501
Query: 543 LNKM 554
LNK+
Sbjct: 502 LNKI 505
[201][TOP]
>UniRef100_A8LPL9 2-isopropylmalate synthase n=1 Tax=Dinoroseobacter shibae DFL 12
RepID=A8LPL9_DINSH
Length = 525
Score = 112 bits (280), Expect = 2e-23
Identities = 72/185 (38%), Positives = 102/185 (55%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQP-EA 179
K SGR AL+ +L +LGY L D QL ++F RFKA+A++KK + D DL+AL+S+ P
Sbjct: 334 KHSGRAALRAKLKDLGYELADNQLKDVFVRFKALADRKKEIYDEDLVALMSESSSDPARE 393
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
+ +++ CGT ++ + L+ DG + + G GPVDA + AV + A L
Sbjct: 394 RLSVKFLRVICGTEAPQSADLTLS-IDGVDKQVTAQGDGPVDATFNAVKALFPHTARLQL 452
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y ++AVTEG DA AT V + D R SG A D VV+S KAYV
Sbjct: 453 YQVHAVTEGTDAQATVTVRMEEDG--------------RIVSGQAADTDTVVASAKAYVA 498
Query: 540 ALNKM 554
ALN++
Sbjct: 499 ALNRL 503
[202][TOP]
>UniRef100_Q2CGZ5 2-isopropylmalate synthase n=1 Tax=Oceanicola granulosus HTCC2516
RepID=Q2CGZ5_9RHOB
Length = 521
Score = 112 bits (280), Expect = 2e-23
Identities = 70/184 (38%), Positives = 105/184 (57%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+ +L +LG+ L D QL+++F RFK +A++KK V D DL+ALV ++V
Sbjct: 331 KHSGRAALRAKLKDLGFDLADNQLNDVFVRFKDLADRKKEVYDEDLVALVRQNEGAEDSV 390
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+L+ +++ CGT G + + + L + DG E + G GPVD+A+ A+ + L Y
Sbjct: 391 -RLVSLRVVCGTGGPAEAEMVL-EVDGAEKSGTARGDGPVDSAFNAIKALYPHDVRLPLY 448
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + D R +G A D VV+S KAY+ A
Sbjct: 449 QVHAVTEGTDAQATVTVRLEEDG--------------RIATGMSADTDTVVASTKAYINA 494
Query: 543 LNKM 554
LN++
Sbjct: 495 LNRL 498
[203][TOP]
>UniRef100_C2K9W8 2-isopropylmalate synthase n=1 Tax=Staphylococcus aureus subsp.
aureus MN8 RepID=C2K9W8_STAAU
Length = 509
Score = 112 bits (280), Expect = 2e-23
Identities = 67/182 (36%), Positives = 104/182 (57%), Gaps = 2/182 (1%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSG+HA ++L LGY +D +LF +FKA+A++KK V+D D+ A++ + +A+
Sbjct: 330 KLSGKHAFSEKLKALGYDIDKEAQIDLFKQFKAIADKKKSVSDRDIHAIIQGSEHEHQAL 389
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL +Q+ + GL ++ V + D +G + S+GTG + A Y AVD I ++ L++Y
Sbjct: 390 YKLETLQLQYVSSGLQSAVVVIKDKEGHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDY 449
Query: 363 SMNAVTEGIDAIATTRV--LIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYV 536
+N+VTEG DA A V LI G +T +G G DI+ +S KAYV
Sbjct: 450 RINSVTEGTDAQAEVHVNLLIEG----------------KTVNGFGIDHDILQASCKAYV 493
Query: 537 GA 542
A
Sbjct: 494 EA 495
[204][TOP]
>UniRef100_C2G5S5 2-isopropylmalate synthase n=6 Tax=Staphylococcus aureus subsp.
aureus RepID=C2G5S5_STAAU
Length = 509
Score = 112 bits (280), Expect = 2e-23
Identities = 67/182 (36%), Positives = 104/182 (57%), Gaps = 2/182 (1%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSG+HA ++L LGY +D +LF +FKA+A++KK V+D D+ A++ + +A+
Sbjct: 330 KLSGKHAFSEKLKALGYDIDKEAQIDLFKQFKAIADKKKSVSDRDIHAIIQGSEHEHQAL 389
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL +Q+ + GL ++ V + D +G + S+GTG + A Y AVD I ++ L++Y
Sbjct: 390 YKLETLQLQYVSSGLQSAVVVIKDKEGHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDY 449
Query: 363 SMNAVTEGIDAIATTRV--LIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYV 536
+N+VTEG DA A V LI G +T +G G DI+ +S KAYV
Sbjct: 450 RINSVTEGTDAQAEVHVNLLIEG----------------KTVNGFGIDHDILQASCKAYV 493
Query: 537 GA 542
A
Sbjct: 494 EA 495
[205][TOP]
>UniRef100_A3K8V5 2-isopropylmalate synthase n=1 Tax=Sagittula stellata E-37
RepID=A3K8V5_9RHOB
Length = 520
Score = 112 bits (280), Expect = 2e-23
Identities = 72/184 (39%), Positives = 106/184 (57%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+ +L +LG + D QL ++F RFK +A++KK V D D++ALVS +A+
Sbjct: 332 KHSGRAALRAKLKDLGTEVGDNQLKDIFVRFKDLADRKKEVFDDDILALVSATTEGADAI 391
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
L+++++ CGT G + + V+L + DGK+ A S G GPVDA +KA+ + A L Y
Sbjct: 392 -TLVNLRVVCGTGGPAEAQVEL-EIDGKDLTATSEGDGPVDATFKAIRALHPNMARLQLY 449
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
+NAVT G DA AT V + D + +G A D VV+S AY+ A
Sbjct: 450 QVNAVTAGTDAQATVSVRLEEDGVIA--------------TGQSADTDTVVASALAYIQA 495
Query: 543 LNKM 554
LN++
Sbjct: 496 LNRL 499
[206][TOP]
>UniRef100_Q1Q0M4 Strongly similar to 2-isopropylmalate synthase n=1 Tax=Candidatus
Kuenenia stuttgartiensis RepID=Q1Q0M4_9BACT
Length = 501
Score = 112 bits (279), Expect = 2e-23
Identities = 63/184 (34%), Positives = 103/184 (55%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGRHA K+R+ ELGY L + + F FK +A++KK + D ++ A++ E + +
Sbjct: 329 KLSGRHAFKERIKELGYDLTEIEFEKAFEEFKRLADKKKEIFDEEIEAIIDTEKMEIPHI 388
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L + I+CG + T+ V++ SDG ++G GP+DA +KA+DL LL+Y
Sbjct: 389 FQLESLSISCGPNVVPTAGVRIRLSDGSVADNATIGDGPIDALFKAIDLATGISGKLLDY 448
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
+ A+T G DA+ V + + G++V+ G DI+ +S KAY+ A
Sbjct: 449 HIQAITSGKDAMGEVYVNV----------DIHGKNVK----GRAVSTDIIEASAKAYLNA 494
Query: 543 LNKM 554
LNK+
Sbjct: 495 LNKV 498
[207][TOP]
>UniRef100_A9HS14 2-isopropylmalate synthase n=1 Tax=Roseobacter litoralis Och 149
RepID=A9HS14_9RHOB
Length = 522
Score = 112 bits (279), Expect = 2e-23
Identities = 69/184 (37%), Positives = 100/184 (54%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+ +L LG+ L D QL ++F RFK +A++KK + D DLIAL+
Sbjct: 334 KHSGRAALRSKLENLGFELGDNQLKDVFVRFKELADRKKEIYDDDLIALMRTATDPENDR 393
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+L+ +++ CGT G + + L + DG E G GPVDA++ A+ +V A L Y
Sbjct: 394 IQLVSLRVVCGTDGPQQADLVL-NIDGVEESTTQTGDGPVDASFNAIKALVAHSARLQLY 452
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA AT V + D R +G A D VV+S +AY+ A
Sbjct: 453 QVHAVTEGTDAQATVSVRMEEDG--------------RIVTGQSADTDTVVASARAYIHA 498
Query: 543 LNKM 554
LN++
Sbjct: 499 LNRL 502
[208][TOP]
>UniRef100_A0NVJ4 2-isopropylmalate synthase n=1 Tax=Labrenzia aggregata IAM 12614
RepID=A0NVJ4_9RHOB
Length = 518
Score = 112 bits (279), Expect = 2e-23
Identities = 70/184 (38%), Positives = 101/184 (54%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA +D+L ELG+ L D L + F RFK +A++KK V D D+ ALV DE+
Sbjct: 335 KHSGRHAFRDKLKELGFELGDNALQDAFRRFKDLADRKKHVYDEDIEALVEDEISVLGES 394
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
K++ + + GT G + + + D +G+ + G GPVDA + A+ IV A L Y
Sbjct: 395 TKVIALTVIAGTGGPQKAILTM-DVNGQHVTKEATGDGPVDATFNAIKAIVPHEAKLSLY 453
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA A V + E+ R +G GA D +V+S +AYV A
Sbjct: 454 QVHAVTEGTDAQAEVSVRL--------------EAGGRIATGKGADTDTLVASARAYVSA 499
Query: 543 LNKM 554
+NK+
Sbjct: 500 MNKL 503
[209][TOP]
>UniRef100_Q6G7Q1 2-isopropylmalate synthase n=3 Tax=Staphylococcus aureus subsp.
aureus RepID=LEU1_STAAS
Length = 509
Score = 112 bits (279), Expect = 2e-23
Identities = 67/182 (36%), Positives = 104/182 (57%), Gaps = 2/182 (1%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSG+HA ++L LGY +D +LF +FKA+A++KK V+D D+ A++ + +A+
Sbjct: 330 KLSGKHAFSEKLKALGYGIDKEAQIDLFKQFKAIADKKKSVSDRDIHAIIQGSEHEHQAL 389
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL +Q+ + GL ++ V + D +G + S+GTG + A Y AVD I ++ L++Y
Sbjct: 390 YKLETLQLQYVSSGLQSAVVVVKDKEGHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDY 449
Query: 363 SMNAVTEGIDAIATTRV--LIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYV 536
+N+VTEG DA A V LI G +T +G G DI+ +S KAYV
Sbjct: 450 RINSVTEGTDAQAEVHVNLLIEG----------------KTVNGFGIDHDILQASCKAYV 493
Query: 537 GA 542
A
Sbjct: 494 EA 495
[210][TOP]
>UniRef100_Q2YUF2 2-isopropylmalate synthase n=1 Tax=Staphylococcus aureus RF122
RepID=LEU1_STAAB
Length = 509
Score = 112 bits (279), Expect = 2e-23
Identities = 67/182 (36%), Positives = 104/182 (57%), Gaps = 2/182 (1%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSG+HA ++L LGY +D +LF +FKA+A++KK V+D D+ A++ + +A+
Sbjct: 330 KLSGKHAFSEKLKALGYDIDKEAQIDLFKQFKAIADKKKSVSDRDIHAIIQGSEHEHQAL 389
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL +Q+ + GL ++ V + D +G + S+GTG + A Y AVD I ++ L++Y
Sbjct: 390 YKLETLQLQYVSSGLQSAVVVVKDKEGHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDY 449
Query: 363 SMNAVTEGIDAIATTRV--LIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYV 536
+N+VTEG DA A V LI G +T +G G DI+ +S KAYV
Sbjct: 450 RINSVTEGTDAQAEVHVNLLIEG----------------KTVNGFGIDHDILQASCKAYV 493
Query: 537 GA 542
A
Sbjct: 494 EA 495
[211][TOP]
>UniRef100_Q2FWK3 2-isopropylmalate synthase n=8 Tax=Staphylococcus aureus
RepID=LEU1_STAA8
Length = 509
Score = 112 bits (279), Expect = 2e-23
Identities = 67/182 (36%), Positives = 104/182 (57%), Gaps = 2/182 (1%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSG+HA ++L LGY +D +LF +FKA+A++KK V+D D+ A++ + +A+
Sbjct: 330 KLSGKHAFSEKLKALGYDIDKEAQIDLFKQFKAIADKKKSVSDRDIHAIIQGSEHEHQAL 389
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL +Q+ + GL ++ V + D +G + S+GTG + A Y AVD I ++ L++Y
Sbjct: 390 YKLETLQLQYVSSGLQSAVVVVKDKEGHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDY 449
Query: 363 SMNAVTEGIDAIATTRV--LIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYV 536
+N+VTEG DA A V LI G +T +G G DI+ +S KAYV
Sbjct: 450 RINSVTEGTDAQAEVHVNLLIEG----------------KTVNGFGIDHDILQASCKAYV 493
Query: 537 GA 542
A
Sbjct: 494 EA 495
[212][TOP]
>UniRef100_A5EP79 2-isopropylmalate synthase n=1 Tax=Bradyrhizobium sp. BTAi1
RepID=LEU1_BRASB
Length = 523
Score = 112 bits (279), Expect = 2e-23
Identities = 69/184 (37%), Positives = 99/184 (53%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA +L E+G+ L Q+ + F RFKA+A++KK + D D+ AL+ + +
Sbjct: 337 KHSGRHAFIHKLEEMGHKLAGNQVEDAFVRFKALADRKKHIYDEDIEALIDEGMVSAHDR 396
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KLL + + GT G +T+KL D DG + S G GPVDA + + +V A L Y
Sbjct: 397 IKLLSLSVIAGTRGPQRATMKL-DVDGVTKIEESEGNGPVDAVFNCIKSLVPHEAKLELY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA A V + D R+ + A D +V+S KAY+GA
Sbjct: 456 QVHAVTEGTDAQAEVSVRLSQDG--------------RSMTARAADPDTLVASAKAYLGA 501
Query: 543 LNKM 554
LNK+
Sbjct: 502 LNKL 505
[213][TOP]
>UniRef100_Q01UL9 2-isopropylmalate synthase n=1 Tax=Candidatus Solibacter usitatus
Ellin6076 RepID=Q01UL9_SOLUE
Length = 509
Score = 111 bits (278), Expect = 3e-23
Identities = 66/182 (36%), Positives = 97/182 (53%)
Frame = +3
Query: 9 SGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWK 188
+GRH L DRL +LGY L D +L + RF +VA++K+ V D DLIA++ DE+ AV++
Sbjct: 330 TGRHGLLDRLRKLGYELSDLELDQAYRRFLSVADKKQEVFDEDLIAILRDEIHPLPAVYE 389
Query: 189 LLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSM 368
L + I GT + T+TV+L S G ++G GPVDA +A+ + A L Y +
Sbjct: 390 LQYLHIYSGTSAIPTATVRLLVS-GDTREGAAIGDGPVDAVCRAISQVTATAAKLQRYEI 448
Query: 369 NAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGALN 548
VT G +A+ + + E R G GA DI+ +S KAY+ LN
Sbjct: 449 RGVTSGTEAMGEVTIQL--------------EEAGRKVIGRGASTDIIEASAKAYLDGLN 494
Query: 549 KM 554
K+
Sbjct: 495 KL 496
[214][TOP]
>UniRef100_Q1K340 2-isopropylmalate synthase n=1 Tax=Desulfuromonas acetoxidans DSM
684 RepID=Q1K340_DESAC
Length = 512
Score = 111 bits (278), Expect = 3e-23
Identities = 69/184 (37%), Positives = 99/184 (53%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA RL LGY L + F RFKA+A+ KK + D DL A+V+DE+ +
Sbjct: 333 KHSGRHAFIQRLESLGYDLSKEDIEKAFVRFKALADVKKEIFDEDLDAIVADEIIRVPER 392
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KLL M ++ G+ T+TV++ + DG+ +G GPVDA +KA+ + LL +
Sbjct: 393 YKLLQMNVSSGSFAAPTATVQM-EVDGEICKTAVIGDGPVDATFKAIKDLSGCDVRLLHF 451
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ A+T G DA V + E R G GA DI+V++ KAY+ A
Sbjct: 452 SVGAITGGTDAQGECTVRL--------------EEQGREQLGQGAHPDIIVAAAKAYINA 497
Query: 543 LNKM 554
LNK+
Sbjct: 498 LNKI 501
[215][TOP]
>UniRef100_A6GIC5 2-isopropylmalate synthase n=1 Tax=Plesiocystis pacifica SIR-1
RepID=A6GIC5_9DELT
Length = 512
Score = 111 bits (278), Expect = 3e-23
Identities = 65/185 (35%), Positives = 102/185 (55%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDE-VFQPEA 179
KLSGRHA ++ L LG+ L+ +L F FKA+A++K V D DL A+ ++ +
Sbjct: 331 KLSGRHAFREHLRGLGHALEGDKLDRAFTAFKALADRKVAVDDRDLEAIAAEHGQTAGHS 390
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
W + +QI+ G T+T++L D DG+ + G+GP+DA Y+AV+ I TL +
Sbjct: 391 AWTVDRVQISSGCSATPTATLRLRDEDGQLREDAATGSGPLDAVYRAVNRITGVEPTLAD 450
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
+S+ +VTEG DA V + E+ R+F+G A DI+V+ +AY
Sbjct: 451 FSIRSVTEGRDAQGEVTVHV--------------EASGRSFAGRAADTDIIVAGARAYTA 496
Query: 540 ALNKM 554
ALN++
Sbjct: 497 ALNRL 501
[216][TOP]
>UniRef100_Q89GB0 2-isopropylmalate synthase n=1 Tax=Bradyrhizobium japonicum
RepID=LEU1_BRAJA
Length = 520
Score = 111 bits (278), Expect = 3e-23
Identities = 70/184 (38%), Positives = 99/184 (53%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA +L E+GY L QL + F R KA+A++KK + D D+ ALV +E+
Sbjct: 337 KHSGRHAFVHKLEEMGYKLGPNQLEDAFTRMKALADRKKDIYDEDIEALVDEEMAASHDR 396
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL + + GT G +T+KL D DG+ + + G GPVDA + + +V A L Y
Sbjct: 397 IKLTSLTVIAGTHGPQRATMKL-DVDGQIKIEEAEGNGPVDAVFNCIKRLVPHEAKLELY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA A V + D R+ + A D +V+S KAY+GA
Sbjct: 456 QVHAVTEGTDAQAEVSVRLSHDG--------------RSMTARAADPDTLVASAKAYLGA 501
Query: 543 LNKM 554
LNK+
Sbjct: 502 LNKI 505
[217][TOP]
>UniRef100_B2V7D9 2-isopropylmalate synthase n=1 Tax=Sulfurihydrogenibium sp. YO3AOP1
RepID=B2V7D9_SULSY
Length = 516
Score = 111 bits (277), Expect = 4e-23
Identities = 64/184 (34%), Positives = 106/184 (57%), Gaps = 1/184 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYV-LDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEA 179
K SGRHA K RL ELGY L + ++ LF +FK +A++KK V D D+ AL+ +E + +
Sbjct: 330 KHSGRHAFKARLEELGYTTLSESEIDTLFQKFKKLADKKKEVFDEDIEALILEEFSEFDQ 389
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
KL + G + T+TVK+ + +G+E V+ + G GP+D A A++ + L++
Sbjct: 390 EAKLKYFHVISGDNVIPTATVKI-EKEGEEIVSTACGDGPIDCAINALEKALNIKGKLMD 448
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y++ +++ G DA+ RV++R +++ E SG G DI+ +S+KAY+
Sbjct: 449 YTIRSLSSGKDAMGEVRVIVRFEDS------------EHIASGKGTSTDIIEASIKAYID 496
Query: 540 ALNK 551
A NK
Sbjct: 497 AYNK 500
[218][TOP]
>UniRef100_B0UKW3 2-isopropylmalate synthase n=1 Tax=Methylobacterium sp. 4-46
RepID=B0UKW3_METS4
Length = 519
Score = 111 bits (277), Expect = 4e-23
Identities = 69/184 (37%), Positives = 101/184 (54%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR A + +L E+GY L D Q + F RFKA+A++KK V D D+ ALV + +
Sbjct: 336 KHSGRAAFRSKLEEMGYRLSDNQFQDAFERFKALADRKKNVYDEDIEALVDENLATAHDR 395
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+L+ + + GT G +T++L D +G+ + G GPVDA + A+ +V A L Y
Sbjct: 396 IRLVSLTVIAGTRGPQRATMRL-DIEGRLATEEADGNGPVDAVFNAIHALVPHEAKLELY 454
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA A V +R ER+ + GA D +V+S KAY+ A
Sbjct: 455 DVHAVTEGTDAQAEVSVRLR--------------QGERSVTARGADPDTLVASAKAYLAA 500
Query: 543 LNKM 554
LNK+
Sbjct: 501 LNKL 504
[219][TOP]
>UniRef100_C4FK94 2-isopropylmalate synthase n=1 Tax=Sulfurihydrogenibium
yellowstonense SS-5 RepID=C4FK94_9AQUI
Length = 516
Score = 111 bits (277), Expect = 4e-23
Identities = 62/184 (33%), Positives = 107/184 (58%), Gaps = 1/184 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYV-LDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEA 179
K SGRHA K RL ELGY L + ++ LF +FK +A++KK V D D+ AL+ +E + +
Sbjct: 330 KHSGRHAFKARLEELGYTTLSESEIDTLFQKFKKLADKKKEVFDEDIEALILEEFSEFDQ 389
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
KL + G + T+TV++ + +G+E ++ + G GP+D A+ A++ + L++
Sbjct: 390 EAKLKYFHVISGDNVIPTATVRI-EKEGQEVISTACGDGPIDCAFNALEKALNIKGKLMD 448
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y++ +++ G DA+ RV++R +++ E SG G DI+ +S+KAY+
Sbjct: 449 YTIRSLSSGKDAMGEVRVIVRFEDS------------EHIASGKGTSTDIIEASIKAYID 496
Query: 540 ALNK 551
A NK
Sbjct: 497 AYNK 500
[220][TOP]
>UniRef100_A3TTT5 2-isopropylmalate synthase n=1 Tax=Oceanicola batsensis HTCC2597
RepID=A3TTT5_9RHOB
Length = 523
Score = 111 bits (277), Expect = 4e-23
Identities = 76/184 (41%), Positives = 100/184 (54%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR ALK +L LG L QL+++F RFK +A++KK V + DL LV D +
Sbjct: 334 KHSGRAALKSKLAALGIDLGQNQLNDVFVRFKDLADRKKEVYEDDLWTLVRDAEDETPDR 393
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+L D+++ CGT G S V L DGKE A + G GPVDA + AV I A L Y
Sbjct: 394 LELKDLKVICGTGGQSAEMVMLV--DGKETRAETSGDGPVDACFNAVKEIFPHQAKLELY 451
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVT+G DA AT V + D R +G A D VV+SVKAY+ A
Sbjct: 452 QVHAVTQGTDAQATVSVRLNEDG--------------RIVTGQSADTDTVVASVKAYLHA 497
Query: 543 LNKM 554
LN++
Sbjct: 498 LNRL 501
[221][TOP]
>UniRef100_Q6GF16 2-isopropylmalate synthase n=1 Tax=Staphylococcus aureus subsp.
aureus MRSA252 RepID=LEU1_STAAR
Length = 509
Score = 111 bits (277), Expect = 4e-23
Identities = 67/182 (36%), Positives = 103/182 (56%), Gaps = 2/182 (1%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSG+HA +L LGY +D +LF +FKA+A++KK V+D D+ A++ + +A+
Sbjct: 330 KLSGKHAFSKKLKALGYDIDKEAQIDLFKQFKAIADKKKSVSDRDIHAIIQGSEHEHQAL 389
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL +Q+ + GL ++ V + D +G + S+GTG + A Y AVD I ++ L++Y
Sbjct: 390 YKLETLQLQYVSSGLQSAVVVIKDKEGHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDY 449
Query: 363 SMNAVTEGIDAIATTRV--LIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYV 536
+N+VTEG DA A V LI G +T +G G DI+ +S KAYV
Sbjct: 450 RINSVTEGTDAQAEVHVNLLIEG----------------KTVNGFGIDHDILQASCKAYV 493
Query: 537 GA 542
A
Sbjct: 494 EA 495
[222][TOP]
>UniRef100_Q47BI0 2-isopropylmalate synthase n=1 Tax=Dechloromonas aromatica RCB
RepID=LEU1_DECAR
Length = 513
Score = 111 bits (277), Expect = 4e-23
Identities = 75/187 (40%), Positives = 103/187 (55%), Gaps = 3/187 (1%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLD-DGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEA 179
K SGR+A K+RL ELG L+ D L+ F RFK +A++K + D DL ALVSD++ P+
Sbjct: 330 KHSGRNAFKNRLQELGIELESDEALNAAFARFKELADKKHEIFDEDLHALVSDDLVTPDQ 389
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
+ L C G + + G EH A + G GPVDA +KA++ I A LL
Sbjct: 390 EYYKLVYSRVCSETGEMPRASVILNIGGVEHKAEADGGGPVDATFKAIESIAGSGAELLL 449
Query: 360 YSMNAVTEGIDA--IATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAY 533
YS+NA+T G DA TTR L +GD R +G GA DIV++S ++Y
Sbjct: 450 YSVNAITTGTDAQGEVTTR-LSKGD---------------RIVNGNGADTDIVIASARSY 493
Query: 534 VGALNKM 554
+ ALNK+
Sbjct: 494 LNALNKL 500
[223][TOP]
>UniRef100_A4XIL8 2-isopropylmalate synthase n=1 Tax=Caldicellulosiruptor
saccharolyticus DSM 8903 RepID=A4XIL8_CALS8
Length = 507
Score = 110 bits (276), Expect = 5e-23
Identities = 69/185 (37%), Positives = 102/185 (55%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYV-LDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEA 179
K SGRHA ++RL ELGY L ++ F +FK +A++KK V D D+ AL+ +
Sbjct: 331 KHSGRHAFEERLKELGYTDLTREEIDAAFEKFKVLADKKKVVLDKDIEALLEQKSLNIPE 390
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++L+ QI G +ST++VK+ + +E+ + G GPVDA +KA+D I L +
Sbjct: 391 TYELVKFQIISGNDLISTASVKIKSGE-EEYEEAATGDGPVDAIFKAIDRITGLQVELDD 449
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
YS+ AVT+G DA+ V I+ D + F G G DI+ +S KAYV
Sbjct: 450 YSIKAVTQGKDALGEVTVRIKKDG--------------KAFLGRGLSTDILEASAKAYVN 495
Query: 540 ALNKM 554
A+NKM
Sbjct: 496 AINKM 500
[224][TOP]
>UniRef100_C4WCT2 2-isopropylmalate synthase n=1 Tax=Staphylococcus warneri L37603
RepID=C4WCT2_STAWA
Length = 511
Score = 110 bits (276), Expect = 5e-23
Identities = 64/180 (35%), Positives = 100/180 (55%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSG+HA ++L LGY + NLF +FK++A++KK V+D D+ AL+ + A+
Sbjct: 330 KLSGKHAFAEKLKALGYDISPDDQINLFKQFKSIADKKKSVSDRDIHALIQGSEHEQSAI 389
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L +Q+ + GL ++ V + D DG + S+GTG + A Y AVD I K L++Y
Sbjct: 390 YQLEALQLQFVSNGLQSAVVVIKDKDGNIYQDSSIGTGSIVAIYNAVDRIFKRETELIDY 449
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
+++VTEG DA A V + DN + +G G DI+ +S KAY+ A
Sbjct: 450 RIDSVTEGTDAQAEVHVNLVIDN--------------KEVNGIGIDHDILKASCKAYIEA 495
[225][TOP]
>UniRef100_C1ZC48 2-isopropylmalate synthase n=1 Tax=Planctomyces limnophilus DSM
3776 RepID=C1ZC48_PLALI
Length = 521
Score = 110 bits (276), Expect = 5e-23
Identities = 67/183 (36%), Positives = 96/183 (52%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA + R+ ELGY LDD +F F +A++KK V DAD+IA++ +
Sbjct: 339 KHSGRHAFRSRVAELGYTLDDETFQRVFDEFIILADKKKSVYDADIIAIIEHQDRNASDR 398
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
WKL I GT + T+TV+L D + H ++G GPVDA KA++ I+ TL Y
Sbjct: 399 WKLQRFHIAAGTGTIPTATVELHDDQHQVHCDAAIGDGPVDAVCKAIERIMGVSGTLDNY 458
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
+ +V+EG DA + +TG R + G DI+ +S +AY+ A
Sbjct: 459 QVRSVSEGKDAQGEVMI-----------ELITG---GRKYHGKAVSTDILEASAQAYLKA 504
Query: 543 LNK 551
LNK
Sbjct: 505 LNK 507
[226][TOP]
>UniRef100_A8DW50 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
RepID=A8DW50_NEMVE
Length = 373
Score = 110 bits (276), Expect = 5e-23
Identities = 74/187 (39%), Positives = 107/187 (57%), Gaps = 3/187 (1%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVL-DDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQ--P 173
KLSGR+A + RL+ELG VL + +L+ F RFK +A++K + D DL ALVSD + + P
Sbjct: 190 KLSGRNAFRSRLDELGIVLAGEAELNAAFARFKDLADKKHEIFDEDLQALVSDTLAEEAP 249
Query: 174 EAVWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATL 353
E +KL+ + + T + + V + DG EH A + G+GPVDA +KA++ I A L
Sbjct: 250 EH-FKLITLDVASKTGEVPQAQV-VVSIDGAEHSANAQGSGPVDATFKAIESIASSEANL 307
Query: 354 LEYSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAY 533
YS+NA+T+G D+ V + E R +G GA DI+V+S KAY
Sbjct: 308 QLYSVNAITQGTDSQGEVTVRL--------------EKGGRIVNGNGADTDILVASAKAY 353
Query: 534 VGALNKM 554
+ ALN M
Sbjct: 354 INALNLM 360
[227][TOP]
>UniRef100_B3QCX5 2-isopropylmalate synthase n=1 Tax=Rhodopseudomonas palustris TIE-1
RepID=LEU1_RHOPT
Length = 524
Score = 110 bits (276), Expect = 5e-23
Identities = 68/184 (36%), Positives = 102/184 (55%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR L ++ ELGY L Q+ ++F RFKA+A++KK V D D+ ALV +++ +
Sbjct: 337 KHSGRAGLIHKMEELGYKLSRNQIEDVFVRFKALADRKKDVYDEDIEALVDEQLLHGQDQ 396
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL+ + + GT G +T+KL D DG+ + + G GPVDA + + +V A L Y
Sbjct: 397 IKLMSLTVIAGTHGPQRATMKL-DVDGQIRIEEAEGNGPVDAVFNCIKALVPHDAKLELY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA A V + + R+ + A D +V+S KAY+GA
Sbjct: 456 QVHAVTEGTDAQAEVSVRLSHEG--------------RSMTARAADPDTLVASAKAYLGA 501
Query: 543 LNKM 554
LNK+
Sbjct: 502 LNKI 505
[228][TOP]
>UniRef100_Q6N858 2-isopropylmalate synthase n=1 Tax=Rhodopseudomonas palustris
RepID=LEU1_RHOPA
Length = 524
Score = 110 bits (276), Expect = 5e-23
Identities = 68/184 (36%), Positives = 102/184 (55%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR L ++ ELGY L Q+ ++F RFKA+A++KK V D D+ ALV +++ +
Sbjct: 337 KHSGRAGLIHKMEELGYKLSRNQIEDVFVRFKALADRKKDVYDEDIEALVDEQLLHGQDQ 396
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL+ + + GT G +T+KL D DG+ + + G GPVDA + + +V A L Y
Sbjct: 397 IKLMSLTVIAGTHGPQRATMKL-DVDGQIRIEEAEGNGPVDAVFNCIKALVPHDAKLELY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA A V + + R+ + A D +V+S KAY+GA
Sbjct: 456 QVHAVTEGTDAQAEVSVRLSHEG--------------RSMTARAADPDTLVASAKAYLGA 501
Query: 543 LNKM 554
LNK+
Sbjct: 502 LNKI 505
[229][TOP]
>UniRef100_B5YEF4 2-isopropylmalate synthase n=1 Tax=Dictyoglomus thermophilum H-6-12
RepID=LEU1_DICT6
Length = 503
Score = 110 bits (276), Expect = 5e-23
Identities = 64/184 (34%), Positives = 103/184 (55%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SG+HA + RL ELGY L QL F +FK +A++KK +TD D+ ALVS+++
Sbjct: 327 KHSGKHAFEKRLQELGYSLPPEQLEEAFKKFKELADKKKEITDKDIEALVSNQIKLVPEY 386
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L+ +Q+ G + T+T+ +++ DG+E +G GPVDA YKA+ +K P +L ++
Sbjct: 387 YRLVHLQVVSGIGIVPTATIIISE-DGEEIKTVEIGNGPVDAVYKAIAKAIKIPHSLEDF 445
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT G DA+ V + + + G DIV +S AY+ A
Sbjct: 446 SLKSVTGGTDALGEAMVKLSDKDG-------------NIYVGRATSTDIVEASALAYLRA 492
Query: 543 LNKM 554
LN++
Sbjct: 493 LNQL 496
[230][TOP]
>UniRef100_Q67KX4 2-isopropylmalate synthase n=1 Tax=Symbiobacterium thermophilum
RepID=Q67KX4_SYMTH
Length = 523
Score = 110 bits (275), Expect = 7e-23
Identities = 65/186 (34%), Positives = 101/186 (54%), Gaps = 2/186 (1%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEA- 179
K SGR A + RL LGY L D ++ + F RFK +A++K+ +TD DL+A+V DE
Sbjct: 330 KHSGRAAFRARLEHLGYQLTDAEIDSAFRRFKELADRKRTITDHDLMAIVGDEQAHRTVT 389
Query: 180 -VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLL 356
V +L Q+ G ++T++V+L +G+ + G GP+ A Y A+D + LL
Sbjct: 390 EVCRLESFQVVAGNERIATASVRLV-REGEVVQEAASGDGPISALYHAIDRAARFEGQLL 448
Query: 357 EYSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYV 536
+Y +NAVTEG DA+ V +R +R SG G D++ +S +AY+
Sbjct: 449 DYRLNAVTEGEDALGEVTVRVRAG--------------DRVASGRGTSTDVIEASARAYM 494
Query: 537 GALNKM 554
A+NK+
Sbjct: 495 NAMNKI 500
[231][TOP]
>UniRef100_C1DUG8 2-isopropylmalate synthase n=1 Tax=Sulfurihydrogenibium azorense
Az-Fu1 RepID=C1DUG8_SULAA
Length = 516
Score = 110 bits (275), Expect = 7e-23
Identities = 66/184 (35%), Positives = 105/184 (57%), Gaps = 1/184 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYV-LDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEA 179
K SGRHA K RL ELGY L D ++ +LF +FK +A++KK V D D+ AL+ +E E
Sbjct: 330 KHSGRHAFKTRLQELGYTNLSDAEIDSLFLKFKKLADKKKEVFDEDIEALILEEFSFFEN 389
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
K+ + G + ++TVK+ + DG+E ++ + G GP+D+ AV+ + LL+
Sbjct: 390 EVKVSYFHVVSGDNVIPSATVKI-EKDGEEIISTASGDGPIDSVINAVEKAIGIKGKLLD 448
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y++ +++ G DA+ RVL++ D+ + SG G DI+ +S+KAYV
Sbjct: 449 YTIRSLSSGKDAMGEVRVLVKFDD------------TDYVASGKGTSTDIIEASLKAYVD 496
Query: 540 ALNK 551
A NK
Sbjct: 497 AYNK 500
[232][TOP]
>UniRef100_C8MBT6 2-isopropylmalate synthase n=1 Tax=Staphylococcus aureus A9635
RepID=C8MBT6_STAAU
Length = 509
Score = 110 bits (275), Expect = 7e-23
Identities = 66/182 (36%), Positives = 103/182 (56%), Gaps = 2/182 (1%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSG+HA ++L LGY +D +LF +FKA+A++KK V+D D+ A++ + +A+
Sbjct: 330 KLSGKHAFSEKLKALGYDIDKEAQIDLFKQFKAIADKKKSVSDRDIHAIIQGSEHEHQAL 389
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL +Q+ + GL ++ V + D +G + S+GTG + A Y AVD I ++ L++Y
Sbjct: 390 YKLETLQLQYVSSGLQSAVVVVKDKEGHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDY 449
Query: 363 SMNAVTEGIDAIATTRV--LIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYV 536
+N+VTEG DA A V LI G +T +G G DI+ +S K YV
Sbjct: 450 RINSVTEGTDAQAEVHVNLLIEG----------------KTVNGFGIDHDILQASCKVYV 493
Query: 537 GA 542
A
Sbjct: 494 EA 495
[233][TOP]
>UniRef100_C6QIH1 2-isopropylmalate synthase n=1 Tax=Hyphomicrobium denitrificans
ATCC 51888 RepID=C6QIH1_9RHIZ
Length = 526
Score = 110 bits (275), Expect = 7e-23
Identities = 70/184 (38%), Positives = 99/184 (53%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR A K +L ELGY L D + + F RFKA+A++KK V D D+ ALV D V
Sbjct: 344 KHSGRAAFKSKLKELGYNLGDNAMEDAFNRFKALADRKKHVYDEDIEALVDDGVAHMNDR 403
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
K+ + + GT+G ++T+ L D +G+ +VG GPVDA + A+ ++ A L Y
Sbjct: 404 VKVAALTVIAGTMGPQSATLTL-DIEGQSKTVQAVGNGPVDATFNAIKQLLPHNARLDLY 462
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA A V + D R +G A D +V+S +AYV A
Sbjct: 463 QVHAVTEGTDAQAEVSVRLEEDG--------------RIVTGRSADPDTLVASARAYVAA 508
Query: 543 LNKM 554
L K+
Sbjct: 509 LTKL 512
[234][TOP]
>UniRef100_C5Q4E2 2-isopropylmalate synthase n=1 Tax=Staphylococcus aureus subsp.
aureus TCH130 RepID=C5Q4E2_STAAU
Length = 509
Score = 110 bits (275), Expect = 7e-23
Identities = 66/182 (36%), Positives = 103/182 (56%), Gaps = 2/182 (1%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSG+HA ++L LGY +D +LF +FK +A++KK V+D D+ A++ + +A+
Sbjct: 330 KLSGKHAFSEKLKALGYDIDKEAQIDLFKQFKTIADKKKSVSDRDIHAIIQGSEHEHQAL 389
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL +Q+ + GL ++ V + D +G + S+GTG + A Y AVD I ++ L++Y
Sbjct: 390 YKLETLQLQYVSSGLQSAVVVVKDKEGHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDY 449
Query: 363 SMNAVTEGIDAIATTRV--LIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYV 536
+N+VTEG DA A V LI G +T +G G DI+ +S KAYV
Sbjct: 450 RINSVTEGTDAQAEVHVNLLIEG----------------KTVNGFGIDHDILQASCKAYV 493
Query: 537 GA 542
A
Sbjct: 494 EA 495
[235][TOP]
>UniRef100_C1SHN1 2-isopropylmalate synthase n=1 Tax=Denitrovibrio acetiphilus DSM
12809 RepID=C1SHN1_9BACT
Length = 519
Score = 110 bits (275), Expect = 7e-23
Identities = 65/183 (35%), Positives = 99/183 (54%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA R+ +LGY +++ + + F FK +A++KK V D D+ +++ ++ +
Sbjct: 332 KHSGRHAFVQRIKDLGYEIENDAMQSAFDEFKILADKKKEVFDEDIESIIFNQAKDEQFA 391
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+ + + I G + T+T+KLAD DG E V S G GPVDA KA++ I L Y
Sbjct: 392 YVMESVNILSGDTAIPTATIKLADKDGNEFVDASTGDGPVDAVMKAIERIAGVGGKLKSY 451
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
+ A+T G DA +G+ S+ G V G G+ D+VV+S KAY+ A
Sbjct: 452 QIKALTAGKDA--------QGEVVLSAEFEECGYDVR----GRGSDTDVVVASAKAYLDA 499
Query: 543 LNK 551
LNK
Sbjct: 500 LNK 502
[236][TOP]
>UniRef100_A3V1U0 2-isopropylmalate synthase n=1 Tax=Loktanella vestfoldensis SKA53
RepID=A3V1U0_9RHOB
Length = 518
Score = 110 bits (275), Expect = 7e-23
Identities = 73/184 (39%), Positives = 101/184 (54%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR AL+ +L ELG+ L D QL+++F RFK +A++KK V D DL+ALV + +
Sbjct: 330 KHSGRAALRAKLAELGFDLADNQLNDVFVRFKDLADRKKEVFDDDLMALVYQNDSGEDRI 389
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL +++ CGT G + + L D DG + + G GPVDA + AV + A L Y
Sbjct: 390 -KLKSLRVICGTEGPQQADMVL-DIDGTDVKTSATGDGPVDATFNAVKALFPHGARLQLY 447
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
+ AVTEG DA AT V + D R +G A D VV+S KAY+ A
Sbjct: 448 QVQAVTEGTDAQATVMVRLDEDG--------------RIATGQSADTDTVVASAKAYINA 493
Query: 543 LNKM 554
LN++
Sbjct: 494 LNRL 497
[237][TOP]
>UniRef100_A7X4N1 2-isopropylmalate synthase n=13 Tax=Staphylococcus aureus
RepID=LEU1_STAA1
Length = 509
Score = 110 bits (275), Expect = 7e-23
Identities = 66/182 (36%), Positives = 103/182 (56%), Gaps = 2/182 (1%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSG+HA ++L LGY +D +LF +FK +A++KK V+D D+ A++ + +A+
Sbjct: 330 KLSGKHAFSEKLKALGYNIDKEAQIDLFKQFKTIADKKKSVSDRDIHAIIQGSEHEHQAL 389
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL +Q+ + GL ++ V + D +G + S+GTG + A Y AVD I ++ L++Y
Sbjct: 390 YKLETLQLQYVSSGLQSAVVVVKDKEGHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDY 449
Query: 363 SMNAVTEGIDAIATTRV--LIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYV 536
+N+VTEG DA A V LI G +T +G G DI+ +S KAYV
Sbjct: 450 RINSVTEGTDAQAEVHVNLLIEG----------------KTVNGFGIDHDILQASCKAYV 493
Query: 537 GA 542
A
Sbjct: 494 EA 495
[238][TOP]
>UniRef100_B8E2W9 2-isopropylmalate synthase n=1 Tax=Dictyoglomus turgidum DSM 6724
RepID=LEU1_DICTD
Length = 503
Score = 110 bits (274), Expect = 9e-23
Identities = 64/184 (34%), Positives = 102/184 (55%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SG+HA + RL ELGY L QL F RFK +A++KK +TD D+ ALVS+++
Sbjct: 327 KHSGKHAFEKRLQELGYSLPPDQLEEAFRRFKELADKKKEITDKDIEALVSNQIRIIPEY 386
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL +Q+ G + T+T+ +++ +G+E +G GPVDA YKA+ VK P +L ++
Sbjct: 387 YKLRHLQVVSGIGIVPTATIIISE-NGEEIKTVEIGNGPVDAVYKAITKAVKVPHSLEDF 445
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ +VT G DA+ V + + + G D++ +S AY+ A
Sbjct: 446 SLKSVTGGTDALGEAMVKLSDKDG-------------NIYVGRATSTDVIEASALAYLRA 492
Query: 543 LNKM 554
LN++
Sbjct: 493 LNQL 496
[239][TOP]
>UniRef100_B8DM91 2-isopropylmalate synthase n=1 Tax=Desulfovibrio vulgaris str.
'Miyazaki F' RepID=LEU1_DESVM
Length = 514
Score = 110 bits (274), Expect = 9e-23
Identities = 62/184 (33%), Positives = 106/184 (57%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR+A+K++L+ELGY L++ QL +F K +A++KK++ D D+ ALV +EV++ +
Sbjct: 333 KHSGRNAVKNKLDELGYRLEEAQLVTVFEAVKKLADKKKQIYDEDIEALVLEEVYRLPDL 392
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
++L+++ + C G+ + + D G+ A G GP+DA + + IV L Y
Sbjct: 393 YRLVNLSVQCSDTGMPPTAAVVMDVMGEVKRAAGFGVGPIDAVFNVIGEIVGRAPVLERY 452
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+ A+T G DA V +R + ++AV G G+ DI+++S +AYV A
Sbjct: 453 SVTAITGGTDAQGEVTVRLR----QNGSSAV----------GRGSDPDIILASARAYVNA 498
Query: 543 LNKM 554
LN++
Sbjct: 499 LNRL 502
[240][TOP]
>UniRef100_Q0BS32 2-isopropylmalate synthase n=1 Tax=Granulibacter bethesdensis
CGDNIH1 RepID=Q0BS32_GRABC
Length = 527
Score = 109 bits (273), Expect = 1e-22
Identities = 73/185 (39%), Positives = 109/185 (58%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGY-VLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEA 179
K SGR A +D+L LGY L + L++ F RFK VA++KK + D D++ALV DEV +
Sbjct: 344 KHSGRAAFRDKLKALGYGELGENALNDAFRRFKEVADRKKVIYDDDIVALVDDEVNRSHE 403
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
+ + +++ G+ G +T+ V+L + DG+ A + G GPVDA + A+ +I L
Sbjct: 404 RIRFVSVEVRAGSRGPATAAVEL-EVDGELKQADAQGDGPVDAIFNAIGIIFTHDVELKL 462
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
YS+ AVT+G DA A RV +R + N G+ V+ G GA D +V+S +AYV
Sbjct: 463 YSVGAVTDGADAQA--RVTVRLEEN--------GKMVD----GQGADTDTMVASTRAYVH 508
Query: 540 ALNKM 554
ALNK+
Sbjct: 509 ALNKL 513
[241][TOP]
>UniRef100_Q0F2J9 2-isopropylmalate synthase n=1 Tax=Mariprofundus ferrooxydans PV-1
RepID=Q0F2J9_9PROT
Length = 514
Score = 109 bits (273), Expect = 1e-22
Identities = 69/184 (37%), Positives = 102/184 (55%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR ALK R +LG LD +L +F RFK +A++KK + D DL+AL+S +
Sbjct: 331 KHSGRAALKSRYGQLGVELDGERLIEVFNRFKLLADKKKDIFDEDLMALLSGDGGVESER 390
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL+ + GT + V L D +G EH A + G GPVDAA+KA+ +V+ LL Y
Sbjct: 391 VKLVSLHTASGTSDAPVAAVVL-DIEGVEHKATAEGDGPVDAAFKAIQSLVEPNGKLLLY 449
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++NA+T G DA V + ++ +R +G G+ DI+V+S +A + A
Sbjct: 450 AVNAITAGTDAQGEVTVRL--------------QNGDRIVNGQGSDTDIIVASARALIAA 495
Query: 543 LNKM 554
LNK+
Sbjct: 496 LNKL 499
[242][TOP]
>UniRef100_C8QZ71 2-isopropylmalate synthase n=1 Tax=Desulfurivibrio alkaliphilus
AHT2 RepID=C8QZ71_9DELT
Length = 513
Score = 109 bits (273), Expect = 1e-22
Identities = 64/185 (34%), Positives = 105/185 (56%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYV-LDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEA 179
K SGRHAL+D++ E+GY L + +++ +F RFKAVA+ KK + + DL A++ DEV +
Sbjct: 330 KHSGRHALRDKIKEMGYTDLGEEEINRVFERFKAVADLKKEMFEEDLEAIIMDEVLRVPE 389
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++LL + G+ L T+ VK+ G+E S+G GP+DAA++A+ + + LL
Sbjct: 390 AFQLLHLGAMSGSRSLPTAAVKML-VRGEEKETASLGVGPIDAAFRAIAQLAGTDSKLLY 448
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
+S++++T G DA V I D + G GA DI+ ++ KAY+
Sbjct: 449 FSVSSITGGTDAQGEVMVRIEDDG--------------KVVVGQGADPDIITAAAKAYLT 494
Query: 540 ALNKM 554
LN++
Sbjct: 495 GLNRL 499
[243][TOP]
>UniRef100_Q2IUT4 2-isopropylmalate synthase n=1 Tax=Rhodopseudomonas palustris HaA2
RepID=LEU1_RHOP2
Length = 524
Score = 109 bits (273), Expect = 1e-22
Identities = 69/184 (37%), Positives = 101/184 (54%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR L +L ELGY L Q+ ++F RFKA+A++KK V D D+ ALV +++ +
Sbjct: 337 KHSGRAGLIHKLEELGYKLSRNQIEDVFVRFKALADRKKDVYDEDIEALVDEQLLHGQDQ 396
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
KL + + GT G +T+KL D DG+ + + G GPVDA + + +V A L Y
Sbjct: 397 IKLNSLTVIAGTHGPQRATMKL-DVDGQIRIEEAEGNGPVDAVFNCIKALVPHDAKLELY 455
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
++AVTEG DA A V + + R+ + A D +V+S KAY+GA
Sbjct: 456 QVHAVTEGTDAQAEVSVRLSHEG--------------RSMTARAADPDTLVASAKAYLGA 501
Query: 543 LNKM 554
LNK+
Sbjct: 502 LNKI 505
[244][TOP]
>UniRef100_A6Q4V5 2-isopropylmalate synthase n=1 Tax=Nitratiruptor sp. SB155-2
RepID=LEU1_NITSB
Length = 514
Score = 109 bits (273), Expect = 1e-22
Identities = 64/182 (35%), Positives = 103/182 (56%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA K ++ ELG+ L + +++ F RFK +A++KK VTD D+ L+++E+ V
Sbjct: 329 KHSGRHAFKKKIEELGFSLSEEEINKAFERFKMLADKKKEVTDDDIRMLITNEIASAPEV 388
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL +QI + G+ ++ V + + +GKE +G G +DA +K +D I L +Y
Sbjct: 389 YKLKKLQINDCSEGVPSAAVTV-EYEGKEITDAGIGDGTIDAIFKTIDRITGVQGKLNDY 447
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
+ AV++G DA+A V + D N + G G +D +++S KAYVGA
Sbjct: 448 QVIAVSKGKDALAKVVVKVVFDEN------------KPAVIGHGLSIDTMIASAKAYVGA 495
Query: 543 LN 548
LN
Sbjct: 496 LN 497
[245][TOP]
>UniRef100_B5EMT9 2-isopropylmalate synthase n=2 Tax=Acidithiobacillus ferrooxidans
RepID=B5EMT9_ACIF5
Length = 513
Score = 109 bits (272), Expect = 2e-22
Identities = 68/184 (36%), Positives = 98/184 (53%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
KLSGR A++ RL LG LD L +F RFK +A++K + D DL ALV++++ + +A
Sbjct: 333 KLSGRAAVRARLEALGIHLDKDVLDTVFTRFKELADRKAEIFDEDLQALVNEDLQEEQAE 392
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
L C +G +G A +VG GPVDAA+KA++ +V LL Y
Sbjct: 393 RYRLGYLRVCSEMGTHPEARVEVLVEGVAKTAAAVGGGPVDAAFKAIEAVVASGVQLLLY 452
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+NA+T G DA V ++ D R +G GA DIV++S KAY+ A
Sbjct: 453 SVNAITTGTDAQGEVTVRLQQDG--------------RIVNGQGADTDIVLASAKAYLSA 498
Query: 543 LNKM 554
LN++
Sbjct: 499 LNRL 502
[246][TOP]
>UniRef100_Q2LWJ3 2-isopropylmalate synthase n=1 Tax=Syntrophus aciditrophicus SB
RepID=LEU1_SYNAS
Length = 516
Score = 109 bits (272), Expect = 2e-22
Identities = 62/184 (33%), Positives = 105/184 (57%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGRHA+ + L +LG+ L D +L+ +F RFK +A+ KK V D DL A+V +E+++ E
Sbjct: 333 KHSGRHAVSEHLKKLGFNLSDTELNKIFVRFKELADAKKNVFDEDLEAIVYEELYRVEDK 392
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
+KL+ + + G + + T+T+++ + D + G GPVDA + A+ I LL Y
Sbjct: 393 YKLIYLNVVSGNVAIPTATMQM-EVDREIVQDAGFGVGPVDATFDAIRKITGTNYDLLRY 451
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
+NA++ G DA V ++ + R+ G GA +D++V+S +AY+ A
Sbjct: 452 VVNAISGGTDAQGEVTVQLKFNG--------------RSVVGHGADLDVIVASARAYINA 497
Query: 543 LNKM 554
LN++
Sbjct: 498 LNRL 501
[247][TOP]
>UniRef100_Q8RL85 2-isopropylmalate synthase n=1 Tax=Geobacillus stearothermophilus
RepID=LEU1_BACST
Length = 515
Score = 109 bits (272), Expect = 2e-22
Identities = 68/185 (36%), Positives = 103/185 (55%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQP-EA 179
K SGRHAL+ R+ ELGY L D +++ LF RFK +A++KK +TD DLIAL+ +E F +
Sbjct: 329 KNSGRHALRYRVEELGYTLSDEEINQLFVRFKELADKKKDITDDDLIALIFEEKFDHFKD 388
Query: 180 VWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++L +Q+ GT + T+ V L G E + G+G V A Y ++ + TLL+
Sbjct: 389 FYQLSSIQVQYGTNQIPTAVVVLKYGKGNEIQEAATGSGSVYALYNTLERCFQTEVTLLD 448
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y + +V G DA+A V +R VE SG G D++ +S KAY+
Sbjct: 449 YRIESVGGGRDALAQVFVKVR------------VRDVET--SGRGTAQDVLEASAKAYIN 494
Query: 540 ALNKM 554
A+N++
Sbjct: 495 AMNRV 499
[248][TOP]
>UniRef100_B8J4F8 2-isopropylmalate synthase n=1 Tax=Desulfovibrio desulfuricans
subsp. desulfuricans str. ATCC 27774 RepID=B8J4F8_DESDA
Length = 515
Score = 108 bits (271), Expect = 2e-22
Identities = 65/185 (35%), Positives = 103/185 (55%), Gaps = 1/185 (0%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR+A++++ +GY LDD QL+ +F K +A++KK + D DL+ALV +E+++
Sbjct: 330 KHSGRNAVRNKFEAMGYKLDDDQLNLIFEAVKQLADRKKNLHDDDLMALVQEEIYRAPDR 389
Query: 183 WKLLDMQI-TCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE 359
++L + + + T G+ + + D DGKE G GPVDA + + +V A L +
Sbjct: 390 FRLRHVSVQSSDTGGVPPTAAVIMDVDGKESSGAGFGVGPVDALFNVIADMVGREAELEQ 449
Query: 360 YSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVG 539
Y++NA+T G DA+ V +R D YS+ G G DI V+S +AYV
Sbjct: 450 YAINAITGGTDALGEVTVRLR-DGEYSAV-------------GRGTHPDIFVASARAYVN 495
Query: 540 ALNKM 554
ALN +
Sbjct: 496 ALNHL 500
[249][TOP]
>UniRef100_B2ULC1 2-isopropylmalate synthase n=1 Tax=Akkermansia muciniphila ATCC
BAA-835 RepID=B2ULC1_AKKM8
Length = 518
Score = 108 bits (271), Expect = 2e-22
Identities = 65/183 (35%), Positives = 101/183 (55%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV 182
K SGR A+K RL +LG+VL + +++ +F RFK V + KK V D DL A+V D + +
Sbjct: 332 KHSGRAAVKSRLEQLGHVLTEEEVNTVFERFKKVGDSKKFVYDDDLSAIVDDSLHASTGL 391
Query: 183 WKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEY 362
W+L +Q G+ T+TV L +GK+ S G G VDA KA++ I + TL Y
Sbjct: 392 WELDFLQFVAGSHARPTATVGLL-KEGKKFEDSSTGNGAVDAVIKAIERITRRKGTLKGY 450
Query: 363 SMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYVGA 542
S+NA +EG DA+ V + ++ + G+ GA D++ +S +AY+ A
Sbjct: 451 SVNAASEGKDALGEVTVHV----DFGQPKPIVGK---------GASTDVIEASARAYLNA 497
Query: 543 LNK 551
+N+
Sbjct: 498 VNR 500
[250][TOP]
>UniRef100_B9YY96 2-isopropylmalate synthase n=1 Tax=Lutiella nitroferrum 2002
RepID=B9YY96_9NEIS
Length = 597
Score = 108 bits (271), Expect = 2e-22
Identities = 69/186 (37%), Positives = 106/186 (56%), Gaps = 2/186 (1%)
Frame = +3
Query: 3 KLSGRHALKDRLNELGYVLDDGQLSNL-FWRFKAVAEQKKRVTDADLIALVSDEVFQ-PE 176
KLSGR+A K +L ELG VL + N F RFK +A++K+ + D DL ALVSDE+ +
Sbjct: 414 KLSGRNAFKTKLAELGIVLSSEEALNAAFARFKELADKKREIFDEDLQALVSDEMVAIDQ 473
Query: 177 AVWKLLDMQITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLL 356
+K + +++ T L + + + + G E A S G+GPVDA +KA++ + K + L
Sbjct: 474 EEFKFVSLKVNTETGELPRAEI-VFNERGAEQRAVSSGSGPVDAVFKAIESVAKSDSELE 532
Query: 357 EYSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTGESVERTFSGTGAGMDIVVSSVKAYV 536
YS+NAVT+G +++ V + D R +G GA D++V+S KAY+
Sbjct: 533 LYSVNAVTKGTESLGEVTVRLARDG--------------RIVNGQGADTDVIVASAKAYL 578
Query: 537 GALNKM 554
ALNK+
Sbjct: 579 SALNKL 584