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[1][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 127 bits (319), Expect(2) = 8e-31
Identities = 63/76 (82%), Positives = 66/76 (86%)
Frame = +3
Query: 27 LKPMEIPVTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPA 206
+K I T MCKKILAHG+TSLHLYTLNVD SAIGILMNLGLIDES ISRSLPWRRPA
Sbjct: 259 VKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMNLGLIDESKISRSLPWRRPA 318
Query: 207 NGFRTREDVRPIFWAN 254
N FRT+EDVRPIFWAN
Sbjct: 319 NVFRTKEDVRPIFWAN 334
Score = 30.0 bits (66), Expect(2) = 8e-31
Identities = 12/13 (92%), Positives = 13/13 (100%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND+AVKAYG
Sbjct: 251 PIKDNDEAVKAYG 263
[2][TOP]
>UniRef100_Q9SE60-2 Isoform 2 of Methylenetetrahydrofolate reductase 1 n=1
Tax=Arabidopsis thaliana RepID=Q9SE60-2
Length = 421
Score = 127 bits (319), Expect(2) = 8e-31
Identities = 63/76 (82%), Positives = 66/76 (86%)
Frame = +3
Query: 27 LKPMEIPVTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPA 206
+K I T MCKKILAHG+TSLHLYTLNVD SAIGILMNLGLIDES ISRSLPWRRPA
Sbjct: 259 VKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMNLGLIDESKISRSLPWRRPA 318
Query: 207 NGFRTREDVRPIFWAN 254
N FRT+EDVRPIFWAN
Sbjct: 319 NVFRTKEDVRPIFWAN 334
Score = 30.0 bits (66), Expect(2) = 8e-31
Identities = 12/13 (92%), Positives = 13/13 (100%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND+AVKAYG
Sbjct: 251 PIKDNDEAVKAYG 263
[3][TOP]
>UniRef100_Q3EAG8 Methylenetetrahydrofolate reductase n=1 Tax=Arabidopsis thaliana
RepID=Q3EAG8_ARATH
Length = 407
Score = 127 bits (319), Expect(2) = 8e-31
Identities = 63/76 (82%), Positives = 66/76 (86%)
Frame = +3
Query: 27 LKPMEIPVTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPA 206
+K I T MCKKILAHG+TSLHLYTLNVD SAIGILMNLGLIDES ISRSLPWRRPA
Sbjct: 259 VKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMNLGLIDESKISRSLPWRRPA 318
Query: 207 NGFRTREDVRPIFWAN 254
N FRT+EDVRPIFWAN
Sbjct: 319 NVFRTKEDVRPIFWAN 334
Score = 30.0 bits (66), Expect(2) = 8e-31
Identities = 12/13 (92%), Positives = 13/13 (100%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND+AVKAYG
Sbjct: 251 PIKDNDEAVKAYG 263
[4][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=B9DHL6_ARATH
Length = 402
Score = 127 bits (319), Expect(2) = 8e-31
Identities = 63/76 (82%), Positives = 66/76 (86%)
Frame = +3
Query: 27 LKPMEIPVTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPA 206
+K I T MCKKILAHG+TSLHLYTLNVD SAIGILMNLGLIDES ISRSLPWRRPA
Sbjct: 69 VKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMNLGLIDESKISRSLPWRRPA 128
Query: 207 NGFRTREDVRPIFWAN 254
N FRT+EDVRPIFWAN
Sbjct: 129 NVFRTKEDVRPIFWAN 144
Score = 30.0 bits (66), Expect(2) = 8e-31
Identities = 12/13 (92%), Positives = 13/13 (100%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND+AVKAYG
Sbjct: 61 PIKDNDEAVKAYG 73
[5][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 117 bits (292), Expect(2) = 3e-27
Identities = 56/76 (73%), Positives = 65/76 (85%)
Frame = +3
Query: 27 LKPMEIPVTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPA 206
+K I + T MCKK+LAHG+ SLHLYTLN++ SA+ ILMNLG+IDES ISRSLPWRRPA
Sbjct: 259 VKAYGIHLGTEMCKKMLAHGVKSLHLYTLNMEKSALAILMNLGMIDESKISRSLPWRRPA 318
Query: 207 NGFRTREDVRPIFWAN 254
N FRT+EDVRPIFWAN
Sbjct: 319 NVFRTKEDVRPIFWAN 334
Score = 28.5 bits (62), Expect(2) = 3e-27
Identities = 11/13 (84%), Positives = 13/13 (100%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDN++AVKAYG
Sbjct: 251 PIKDNEEAVKAYG 263
[6][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 108 bits (270), Expect(2) = 3e-25
Identities = 51/76 (67%), Positives = 61/76 (80%)
Frame = +3
Query: 27 LKPMEIPVTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPA 206
+K I + T MCKKILAHG+ ++HLYTLN++ SA+ ILMNLGLI+ES ISR PWRRP
Sbjct: 259 VKAYGIHLGTEMCKKILAHGIKTVHLYTLNMEKSALAILMNLGLIEESKISRPFPWRRPT 318
Query: 207 NGFRTREDVRPIFWAN 254
N FR +EDVRPIFWAN
Sbjct: 319 NVFRVKEDVRPIFWAN 334
Score = 30.0 bits (66), Expect(2) = 3e-25
Identities = 12/13 (92%), Positives = 13/13 (100%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND+AVKAYG
Sbjct: 251 PIKDNDEAVKAYG 263
[7][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 108 bits (270), Expect(2) = 3e-25
Identities = 51/76 (67%), Positives = 61/76 (80%)
Frame = +3
Query: 27 LKPMEIPVTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPA 206
+K I + T MCKKILAHG+ ++HLYTLN++ SA+ ILMNLGLI+ES ISR PWRRP
Sbjct: 259 VKAYGIHLGTEMCKKILAHGIKTVHLYTLNMEKSALAILMNLGLIEESKISRPFPWRRPT 318
Query: 207 NGFRTREDVRPIFWAN 254
N FR +EDVRPIFWAN
Sbjct: 319 NVFRVKEDVRPIFWAN 334
Score = 30.0 bits (66), Expect(2) = 3e-25
Identities = 12/13 (92%), Positives = 13/13 (100%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND+AVKAYG
Sbjct: 251 PIKDNDEAVKAYG 263
[8][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 108 bits (271), Expect(2) = 7e-25
Identities = 53/76 (69%), Positives = 62/76 (81%)
Frame = +3
Query: 27 LKPMEIPVTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPA 206
+K I + T MCKKILA G+ +LHLYTLN++ SA+GILMNLGLI+ES ISRSLPWR P
Sbjct: 259 VKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALGILMNLGLIEESKISRSLPWRPPT 318
Query: 207 NGFRTREDVRPIFWAN 254
N FR +EDVRPIFWAN
Sbjct: 319 NVFRVKEDVRPIFWAN 334
Score = 28.5 bits (62), Expect(2) = 7e-25
Identities = 11/13 (84%), Positives = 13/13 (100%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDN++AVKAYG
Sbjct: 251 PIKDNEEAVKAYG 263
[9][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 108 bits (271), Expect(2) = 7e-25
Identities = 53/76 (69%), Positives = 62/76 (81%)
Frame = +3
Query: 27 LKPMEIPVTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPA 206
+K I + T MCKKILA G+ +LHLYTLN++ SA+GILMNLGLI+ES ISRSLPWR P
Sbjct: 259 VKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALGILMNLGLIEESKISRSLPWRPPT 318
Query: 207 NGFRTREDVRPIFWAN 254
N FR +EDVRPIFWAN
Sbjct: 319 NVFRVKEDVRPIFWAN 334
Score = 28.5 bits (62), Expect(2) = 7e-25
Identities = 11/13 (84%), Positives = 13/13 (100%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDN++AVKAYG
Sbjct: 251 PIKDNEEAVKAYG 263
[10][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 107 bits (267), Expect(2) = 5e-24
Identities = 50/71 (70%), Positives = 60/71 (84%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFRT 221
I + T MCKKILAHG+ +LHLYTLN++ SA+ ILMNLGLI+ES I+R+LPWR P N FR
Sbjct: 278 IHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILMNLGLIEESKITRALPWRPPTNVFRA 337
Query: 222 REDVRPIFWAN 254
+EDVRPIFWAN
Sbjct: 338 KEDVRPIFWAN 348
Score = 27.3 bits (59), Expect(2) = 5e-24
Identities = 10/13 (76%), Positives = 13/13 (100%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDN++AV+AYG
Sbjct: 265 PIKDNEEAVRAYG 277
[11][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 106 bits (265), Expect(2) = 8e-24
Identities = 50/71 (70%), Positives = 59/71 (83%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFRT 221
I + T MCKKILAHG+ +LHLYTLN++ SA+ ILMNLGLI+ES I+R LPWR P N FR
Sbjct: 275 IHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILMNLGLIEESKITRPLPWRPPTNVFRV 334
Query: 222 REDVRPIFWAN 254
+EDVRPIFWAN
Sbjct: 335 KEDVRPIFWAN 345
Score = 27.3 bits (59), Expect(2) = 8e-24
Identities = 10/13 (76%), Positives = 13/13 (100%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDN++AV+AYG
Sbjct: 262 PIKDNEEAVRAYG 274
[12][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 105 bits (263), Expect(2) = 2e-23
Identities = 52/76 (68%), Positives = 60/76 (78%)
Frame = +3
Query: 27 LKPMEIPVTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPA 206
+K I + T MCKKILA G+ +LHLYTLN+D SAIGILMNLGLI+ES +SR LPWR
Sbjct: 259 VKQYGIHLGTEMCKKILATGIKTLHLYTLNMDKSAIGILMNLGLIEESKVSRPLPWRPAT 318
Query: 207 NGFRTREDVRPIFWAN 254
N FR +EDVRPIFWAN
Sbjct: 319 NVFRVKEDVRPIFWAN 334
Score = 26.6 bits (57), Expect(2) = 2e-23
Identities = 10/13 (76%), Positives = 12/13 (92%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDN++AVK YG
Sbjct: 251 PIKDNEEAVKQYG 263
[13][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 103 bits (258), Expect(2) = 2e-23
Identities = 49/76 (64%), Positives = 61/76 (80%)
Frame = +3
Query: 27 LKPMEIPVTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPA 206
+K I + T MCKKILA G+ +LHLYTLN++ +A+ ILMNLGLI+ES +SR+LPWR P
Sbjct: 247 VKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKTALAILMNLGLIEESKLSRTLPWRPPT 306
Query: 207 NGFRTREDVRPIFWAN 254
N FR +EDVRPIFWAN
Sbjct: 307 NVFRVKEDVRPIFWAN 322
Score = 28.5 bits (62), Expect(2) = 2e-23
Identities = 11/13 (84%), Positives = 13/13 (100%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDN++AVKAYG
Sbjct: 239 PIKDNEEAVKAYG 251
[14][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 104 bits (259), Expect(2) = 4e-23
Identities = 49/71 (69%), Positives = 58/71 (81%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFRT 221
I + T MCKKI+AHG+ +LHLYTLN++ SA+ ILMNLGLI+ES ISR LPWR P N FR
Sbjct: 279 IHLGTEMCKKIMAHGIKTLHLYTLNMEKSALAILMNLGLIEESKISRPLPWRPPTNVFRV 338
Query: 222 REDVRPIFWAN 254
+E VRPIFWAN
Sbjct: 339 KEGVRPIFWAN 349
Score = 27.3 bits (59), Expect(2) = 4e-23
Identities = 10/13 (76%), Positives = 13/13 (100%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDN++AV+AYG
Sbjct: 266 PIKDNEEAVRAYG 278
[15][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 105 bits (261), Expect(2) = 8e-23
Identities = 51/71 (71%), Positives = 58/71 (81%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFRT 221
I + T MCKKILA G+ +LHLYTLN+D SAIGILMNLGLI+ES +SR LPWR N FR
Sbjct: 264 IHLGTEMCKKILATGIKTLHLYTLNMDKSAIGILMNLGLIEESKVSRPLPWRPATNVFRV 323
Query: 222 REDVRPIFWAN 254
+EDVRPIFWAN
Sbjct: 324 KEDVRPIFWAN 334
Score = 25.4 bits (54), Expect(2) = 8e-23
Identities = 9/13 (69%), Positives = 12/13 (92%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDN++AV+ YG
Sbjct: 251 PIKDNEEAVRQYG 263
[16][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 100 bits (248), Expect(2) = 2e-22
Identities = 47/71 (66%), Positives = 56/71 (78%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFRT 221
I + T MCKKILAH + +LHLY+LN++ S +GIL NLGLID S +SR LPWR P N RT
Sbjct: 264 IHLGTEMCKKILAHDIRTLHLYSLNLEKSVLGILQNLGLIDFSRVSRPLPWRPPTNSKRT 323
Query: 222 REDVRPIFWAN 254
+EDVRPIFWAN
Sbjct: 324 KEDVRPIFWAN 334
Score = 28.9 bits (63), Expect(2) = 2e-22
Identities = 11/13 (84%), Positives = 13/13 (100%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND+AV+AYG
Sbjct: 251 PIKDNDEAVRAYG 263
[17][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 99.0 bits (245), Expect(2) = 5e-22
Identities = 46/71 (64%), Positives = 56/71 (78%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFRT 221
I + T MCKKILAH + +LHLY+LN++ S +GIL NLGLID S ++R LPWR P N RT
Sbjct: 264 IHLGTEMCKKILAHDIRTLHLYSLNLEKSVLGILQNLGLIDFSKVTRPLPWRPPTNSKRT 323
Query: 222 REDVRPIFWAN 254
+EDVRPIFWAN
Sbjct: 324 KEDVRPIFWAN 334
Score = 28.9 bits (63), Expect(2) = 5e-22
Identities = 11/13 (84%), Positives = 13/13 (100%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND+AV+AYG
Sbjct: 251 PIKDNDEAVRAYG 263
[18][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 98.2 bits (243), Expect(2) = 3e-21
Identities = 47/71 (66%), Positives = 56/71 (78%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFRT 221
I + T MCKKILAHG+ +LHLYTLN++ SA+GIL NLGLID + I R LPWR N RT
Sbjct: 264 IHLGTEMCKKILAHGIKTLHLYTLNMEKSALGILANLGLIDMTKIRRPLPWRPATNVLRT 323
Query: 222 REDVRPIFWAN 254
+E+VRPIFWAN
Sbjct: 324 KENVRPIFWAN 334
Score = 27.3 bits (59), Expect(2) = 3e-21
Identities = 10/13 (76%), Positives = 13/13 (100%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDN++AV+AYG
Sbjct: 251 PIKDNEEAVRAYG 263
[19][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 78.6 bits (192), Expect(2) = 3e-16
Identities = 42/76 (55%), Positives = 51/76 (67%)
Frame = +3
Query: 27 LKPMEIPVTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPA 206
+K I + T MCKKILAHG+ + L T+++ NLGLI+ES ISR PWRRP
Sbjct: 259 VKAYGIHLGTEMCKKILAHGIKTFGL-TMDLP------WQNLGLIEESKISRPFPWRRPT 311
Query: 207 NGFRTREDVRPIFWAN 254
N FR +EDVRPIFWAN
Sbjct: 312 NVFRVKEDVRPIFWAN 327
Score = 30.0 bits (66), Expect(2) = 3e-16
Identities = 12/13 (92%), Positives = 13/13 (100%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND+AVKAYG
Sbjct: 251 PIKDNDEAVKAYG 263
[20][TOP]
>UniRef100_C6T731 Methylenetetrahydrofolate reductase n=1 Tax=Glycine max
RepID=C6T731_SOYBN
Length = 344
Score = 62.8 bits (151), Expect(3) = 3e-15
Identities = 30/48 (62%), Positives = 39/48 (81%)
Frame = +3
Query: 27 LKPMEIPVTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDES 170
+K I + T MCKKILAHG+ +LHLYTLN++ SA+ ILMNLGLI+E+
Sbjct: 260 VKAYGIHLGTEMCKKILAHGINTLHLYTLNMEKSALAILMNLGLIEET 307
Score = 33.5 bits (75), Expect(3) = 3e-15
Identities = 18/27 (66%), Positives = 19/27 (70%)
Frame = +1
Query: 172 QFLVLYLGDALQMVSVLGKMFAQFSGQ 252
+FL YLGDALQM SVL KM Q GQ
Sbjct: 308 KFLGPYLGDALQMFSVLKKMSVQSFGQ 334
Score = 28.5 bits (62), Expect(3) = 3e-15
Identities = 11/13 (84%), Positives = 13/13 (100%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDN++AVKAYG
Sbjct: 252 PIKDNEEAVKAYG 264
[21][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 72.0 bits (175), Expect(2) = 1e-13
Identities = 36/78 (46%), Positives = 51/78 (65%), Gaps = 2/78 (2%)
Frame = +3
Query: 27 LKPMEIPVTTGMCKKILAHG-LTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRR- 200
+K I + MC+++LA G + +H+YTLN++ SA+ IL LGL+D S + R LPWR
Sbjct: 253 VKAYGIDLGVRMCRQLLASGEVPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHV 312
Query: 201 PANGFRTREDVRPIFWAN 254
PA R E VRP+FW+N
Sbjct: 313 PAGTARAVEQVRPVFWSN 330
Score = 27.3 bits (59), Expect(2) = 1e-13
Identities = 11/12 (91%), Positives = 12/12 (100%)
Frame = +2
Query: 5 IKDNDDAVKAYG 40
IKDND+AVKAYG
Sbjct: 246 IKDNDEAVKAYG 257
[22][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 70.9 bits (172), Expect(2) = 9e-12
Identities = 35/77 (45%), Positives = 50/77 (64%), Gaps = 1/77 (1%)
Frame = +3
Query: 27 LKPMEIPVTTGMCKKILAHG-LTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRP 203
++ I T +CKK+LA + +H+YTLN + + + +L +GL E +I +SLPWR
Sbjct: 277 IRKFGIVEATNLCKKLLASDDVPGIHVYTLNREEAVVKLLKRVGLWHEESIYKSLPWRPS 336
Query: 204 ANGFRTREDVRPIFWAN 254
ANG R EDVRPIFWA+
Sbjct: 337 ANGKRISEDVRPIFWAS 353
Score = 22.3 bits (46), Expect(2) = 9e-12
Identities = 7/12 (58%), Positives = 11/12 (91%)
Frame = +2
Query: 5 IKDNDDAVKAYG 40
IKDND+A++ +G
Sbjct: 270 IKDNDEAIRKFG 281
[23][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 61.6 bits (148), Expect(2) = 4e-10
Identities = 30/76 (39%), Positives = 44/76 (57%)
Frame = +3
Query: 27 LKPMEIPVTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPA 206
+K + + M K++L G+ LH YTLN++ S +L L L+ +S LPW + A
Sbjct: 252 VKKYGVRLCVEMSKRLLDFGVEGLHFYTLNLERSVRKVLKGLQLVTPDQLSPFLPWAQSA 311
Query: 207 NGFRTREDVRPIFWAN 254
G R +E+VRPIFW N
Sbjct: 312 AGNRLKEEVRPIFWQN 327
Score = 26.2 bits (56), Expect(2) = 4e-10
Identities = 10/13 (76%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND+ VK YG
Sbjct: 244 PIKDNDEEVKKYG 256
[24][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 58.9 bits (141), Expect(2) = 6e-09
Identities = 35/74 (47%), Positives = 47/74 (63%), Gaps = 1/74 (1%)
Frame = +3
Query: 36 MEIPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANG 212
+E+ VT MCK++LA GL LH YTLN + + + +L LG+ +E R LPW A+
Sbjct: 293 IELAVT--MCKELLASGLVPGLHFYTLNREVATMEVLKRLGMWNEDP-RRPLPWAVSAHP 349
Query: 213 FRTREDVRPIFWAN 254
R EDVRPIFWA+
Sbjct: 350 KRRVEDVRPIFWAS 363
Score = 24.6 bits (52), Expect(2) = 6e-09
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 280 PIKDNDAAIRNYG 292
[25][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 57.4 bits (137), Expect(2) = 2e-08
Identities = 33/74 (44%), Positives = 47/74 (63%), Gaps = 1/74 (1%)
Frame = +3
Query: 36 MEIPVTTGMCKKILAHGLTS-LHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANG 212
+E+ VT MC+++L G+ S LH YTLN + + + +L LG+ +E R LPW A+
Sbjct: 296 IELAVT--MCRELLVSGVVSGLHFYTLNREVATVEVLKRLGIWNEDP-RRPLPWAVSAHP 352
Query: 213 FRTREDVRPIFWAN 254
R EDVRPIFWA+
Sbjct: 353 KRRVEDVRPIFWAS 366
Score = 24.6 bits (52), Expect(2) = 2e-08
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 283 PIKDNDAAIRNYG 295
[26][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 62.0 bits (149), Expect = 2e-08
Identities = 31/69 (44%), Positives = 42/69 (60%), Gaps = 2/69 (2%)
Frame = +3
Query: 48 VTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLI--DESTISRSLPWRRPANGFRT 221
+ MCKK+LA G+ LH YT+N+ + +L LGLI E+ + + LPWR+ R
Sbjct: 257 LVANMCKKMLASGIHHLHFYTMNLQQATKMVLDELGLIPSHETPLQKPLPWRQSLGLGRR 316
Query: 222 REDVRPIFW 248
EDVRPIFW
Sbjct: 317 EEDVRPIFW 325
[27][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 62.0 bits (149), Expect = 2e-08
Identities = 31/69 (44%), Positives = 42/69 (60%), Gaps = 2/69 (2%)
Frame = +3
Query: 48 VTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLI--DESTISRSLPWRRPANGFRT 221
+ MCKK+LA G+ LH YT+N+ + +L LGLI E+ + + LPWR+ R
Sbjct: 257 LVANMCKKMLASGIHHLHFYTMNLQQATKMVLDELGLIPSHETPLQKPLPWRQSLGLGRR 316
Query: 222 REDVRPIFW 248
EDVRPIFW
Sbjct: 317 EEDVRPIFW 325
[28][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 62.0 bits (149), Expect = 2e-08
Identities = 31/69 (44%), Positives = 42/69 (60%), Gaps = 2/69 (2%)
Frame = +3
Query: 48 VTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLI--DESTISRSLPWRRPANGFRT 221
+ MCKK+LA G+ LH YT+N+ + +L LGLI E+ + + LPWR+ R
Sbjct: 257 LVANMCKKMLASGIHHLHFYTMNLQQATKMVLDELGLIPSHETPLQKPLPWRQSLGLGRR 316
Query: 222 REDVRPIFW 248
EDVRPIFW
Sbjct: 317 EEDVRPIFW 325
[29][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 61.6 bits (148), Expect = 3e-08
Identities = 32/65 (49%), Positives = 41/65 (63%), Gaps = 2/65 (3%)
Frame = +3
Query: 60 MCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLI--DESTISRSLPWRRPANGFRTREDV 233
MCKKILA G+ LH YT+N+ + IL LGLI ++ + + LPWR+ R EDV
Sbjct: 261 MCKKILASGIYHLHFYTMNLQQATKMILDELGLIPSHKTPLQKPLPWRQSLGLGRREEDV 320
Query: 234 RPIFW 248
RPIFW
Sbjct: 321 RPIFW 325
[30][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 61.6 bits (148), Expect = 3e-08
Identities = 32/65 (49%), Positives = 41/65 (63%), Gaps = 2/65 (3%)
Frame = +3
Query: 60 MCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLI--DESTISRSLPWRRPANGFRTREDV 233
MCKKILA G+ LH YT+N+ + IL LGLI ++ + + LPWR+ R EDV
Sbjct: 261 MCKKILASGIYHLHFYTMNLQQATKMILDELGLIPSHKTPLQKPLPWRQSLGLGRREEDV 320
Query: 234 RPIFW 248
RPIFW
Sbjct: 321 RPIFW 325
[31][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 61.6 bits (148), Expect = 3e-08
Identities = 32/67 (47%), Positives = 41/67 (61%), Gaps = 2/67 (2%)
Frame = +3
Query: 60 MCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLI--DESTISRSLPWRRPANGFRTREDV 233
MC+K+LA GL LH YT+N+ + +L L LI +E+ + R LPWR R EDV
Sbjct: 261 MCRKLLAAGLNHLHFYTMNLAQATQSVLDELKLIPSEETPLQRPLPWRPSLGLNRRGEDV 320
Query: 234 RPIFWAN 254
RPIFW N
Sbjct: 321 RPIFWRN 327
[32][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 56.6 bits (135), Expect(2) = 3e-08
Identities = 31/72 (43%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I + +C+++LA GL LH YTLN + + +L LG+ E R LPW A+ R
Sbjct: 340 IELAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDP-RRPLPWALSAHPKR 398
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 399 REEDVRPIFWAS 410
Score = 24.6 bits (52), Expect(2) = 3e-08
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 327 PIKDNDAAIRNYG 339
[33][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 56.6 bits (135), Expect(2) = 3e-08
Identities = 31/72 (43%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I + +C+++LA GL LH YTLN + + +L LG+ E R LPW A+ R
Sbjct: 322 IELAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDP-RRPLPWALSAHPKR 380
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 381 REEDVRPIFWAS 392
Score = 24.6 bits (52), Expect(2) = 3e-08
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 309 PIKDNDAAIRNYG 321
[34][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 56.6 bits (135), Expect(2) = 3e-08
Identities = 31/72 (43%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I + +C+++LA GL LH YTLN + + +L LG+ E R LPW A+ R
Sbjct: 329 IELAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDP-RRPLPWALSAHPKR 387
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 388 REEDVRPIFWAS 399
Score = 24.6 bits (52), Expect(2) = 3e-08
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 316 PIKDNDAAIRNYG 328
[35][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 56.6 bits (135), Expect(2) = 3e-08
Identities = 31/72 (43%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I + +C+++LA GL LH YTLN + + +L LG+ E R LPW A+ R
Sbjct: 299 IELAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDP-RRPLPWALSAHPKR 357
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 358 REEDVRPIFWAS 369
Score = 24.6 bits (52), Expect(2) = 3e-08
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 286 PIKDNDAAIRNYG 298
[36][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 56.2 bits (134), Expect(2) = 3e-08
Identities = 32/73 (43%), Positives = 46/73 (63%), Gaps = 2/73 (2%)
Frame = +3
Query: 42 IPVTTGMCKKILAHG-LTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPAN-GF 215
I + T MC+ +L G + LH+YTLN++ + I IL NLGL + +++ LPW+ AN
Sbjct: 271 IDLATDMCRTLLNSGKVHGLHMYTLNLETATIQILKNLGLWCQD-VAKPLPWKTSANPER 329
Query: 216 RTREDVRPIFWAN 254
R E VRPIFW +
Sbjct: 330 RENETVRPIFWCD 342
Score = 25.0 bits (53), Expect(2) = 3e-08
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 258 PIKDNDAAIRKYG 270
[37][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 56.6 bits (135), Expect(2) = 3e-08
Identities = 31/72 (43%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I + MC+++L GL LH YTLN + + I +L LG+ E R +PW A+ R
Sbjct: 293 IDLAVSMCRELLDSGLVHGLHFYTLNREVATIDVLKRLGMWKEDP-RRPMPWAMSAHPKR 351
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 352 RVEDVRPIFWAS 363
Score = 24.6 bits (52), Expect(2) = 3e-08
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 280 PIKDNDAAIRNYG 292
[38][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 56.6 bits (135), Expect(2) = 3e-08
Identities = 32/72 (44%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I + MC+++L GL LH YTLN + + I +L LG+ E R LPW A+ R
Sbjct: 293 IDLAVSMCRELLDSGLVHGLHFYTLNREVATIDVLKRLGMWKEDP-RRPLPWAVSAHPKR 351
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 352 RVEDVRPIFWAS 363
Score = 24.6 bits (52), Expect(2) = 3e-08
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 280 PIKDNDAAIRNYG 292
[39][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 56.6 bits (135), Expect(2) = 3e-08
Identities = 32/72 (44%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I + MC+++L GL LH YTLN + + I +L LG+ E R LPW A+ R
Sbjct: 293 IDLAVSMCRELLDSGLVHGLHFYTLNREVATIDVLKRLGMWKEDP-RRPLPWAVSAHPKR 351
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 352 RVEDVRPIFWAS 363
Score = 24.6 bits (52), Expect(2) = 3e-08
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 280 PIKDNDAAIRNYG 292
[40][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 56.2 bits (134), Expect(2) = 4e-08
Identities = 33/72 (45%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I +C+++LA GL LH YTLN + + I +L LGL E R LPW A+ R
Sbjct: 298 IEQAVSLCQELLASGLVPGLHFYTLNREVATIEVLKRLGLWIEDP-RRPLPWALSAHPKR 356
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 357 RVEDVRPIFWAS 368
Score = 24.6 bits (52), Expect(2) = 4e-08
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 285 PIKDNDAAIRNYG 297
[41][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 56.2 bits (134), Expect(2) = 4e-08
Identities = 33/72 (45%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I +C+++LA GL LH YTLN + + I +L LGL E R LPW A+ R
Sbjct: 298 IEQAVSLCQELLASGLVPGLHFYTLNREVATIEVLKRLGLWIEDP-RRPLPWALSAHPKR 356
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 357 RVEDVRPIFWAS 368
Score = 24.6 bits (52), Expect(2) = 4e-08
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 285 PIKDNDAAIRNYG 297
[42][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 55.8 bits (133), Expect(2) = 5e-08
Identities = 31/72 (43%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I + +C ++LA GL LH YTLN + + +L LG+ E R LPW A+ R
Sbjct: 340 IELAVSLCHELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDP-RRPLPWALSAHPKR 398
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 399 REEDVRPIFWAS 410
Score = 24.6 bits (52), Expect(2) = 5e-08
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 327 PIKDNDAAIRNYG 339
[43][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 55.5 bits (132), Expect(2) = 5e-08
Identities = 31/66 (46%), Positives = 41/66 (62%), Gaps = 1/66 (1%)
Frame = +3
Query: 60 MCKKILAHGLTS-LHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFRTREDVR 236
M +++ GL + LH YTLN + + I IL +GL E I R PW+R AN R E+VR
Sbjct: 294 MIRELFDSGLVNGLHFYTLNREVATIQILKQIGLWTED-IQRPWPWKRTANYNRCEEEVR 352
Query: 237 PIFWAN 254
PIFWA+
Sbjct: 353 PIFWAS 358
Score = 25.0 bits (53), Expect(2) = 5e-08
Identities = 8/13 (61%), Positives = 12/13 (92%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PI+DND+A++ YG
Sbjct: 275 PIRDNDEAIRNYG 287
[44][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 55.8 bits (133), Expect(2) = 5e-08
Identities = 31/72 (43%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I + +C ++LA GL LH YTLN + + +L LG+ E R LPW A+ R
Sbjct: 322 IELAVSLCHELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDP-RRPLPWALSAHPKR 380
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 381 REEDVRPIFWAS 392
Score = 24.6 bits (52), Expect(2) = 5e-08
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 309 PIKDNDAAIRNYG 321
[45][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 55.8 bits (133), Expect(2) = 5e-08
Identities = 31/72 (43%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I + +C ++LA GL LH YTLN + + +L LG+ E R LPW A+ R
Sbjct: 299 IELAVSLCHELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDP-RRPLPWALSAHPKR 357
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 358 REEDVRPIFWAS 369
Score = 24.6 bits (52), Expect(2) = 5e-08
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 286 PIKDNDAAIRNYG 298
[46][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 60.5 bits (145), Expect = 6e-08
Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 6/82 (7%)
Frame = +3
Query: 27 LKPMEIPVTTGMCKKILAHGLT------SLHLYTLNVD*SAIGILMNLGLIDESTISRSL 188
+K + + + MC +I+++G+ LH YTLN++ S I+ L ++D +R L
Sbjct: 224 VKDLGVEICVAMCSQIMSYGVDHTHSSGGLHFYTLNLESSVCRIIERLMMVDNHVATRVL 283
Query: 189 PWRRPANGFRTREDVRPIFWAN 254
PWR R E+VRPIFW N
Sbjct: 284 PWRPSKASSRQEENVRPIFWRN 305
[47][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 60.5 bits (145), Expect = 6e-08
Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 6/82 (7%)
Frame = +3
Query: 27 LKPMEIPVTTGMCKKILAHGLT------SLHLYTLNVD*SAIGILMNLGLIDESTISRSL 188
+K + + + MC +I+++G+ LH YTLN++ S I+ L ++D +R L
Sbjct: 224 VKDLGVEICVAMCSQIMSYGVDHTHSSGGLHFYTLNLESSVCRIIERLMMVDNHVATRVL 283
Query: 189 PWRRPANGFRTREDVRPIFWAN 254
PWR R E+VRPIFW N
Sbjct: 284 PWRPSKASSRQEENVRPIFWRN 305
[48][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 55.5 bits (132), Expect(2) = 7e-08
Identities = 30/72 (41%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I + +C+++L GL LH YTLN + + + +L LG+ E R LPW A+ R
Sbjct: 339 IELAVSLCRELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTEDP-RRPLPWALSAHPKR 397
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 398 REEDVRPIFWAS 409
Score = 24.6 bits (52), Expect(2) = 7e-08
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 326 PIKDNDAAIRNYG 338
[49][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 55.5 bits (132), Expect(2) = 7e-08
Identities = 30/72 (41%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I + +C+++L GL LH YTLN + + + +L LG+ E R LPW A+ R
Sbjct: 339 IELAVSLCRELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTEDP-RRPLPWALSAHPKR 397
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 398 REEDVRPIFWAS 409
Score = 24.6 bits (52), Expect(2) = 7e-08
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 326 PIKDNDAAIRNYG 338
[50][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 55.5 bits (132), Expect(2) = 7e-08
Identities = 30/72 (41%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I + +C+++L GL LH YTLN + + + +L LG+ E R LPW A+ R
Sbjct: 339 IELAVSLCRELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTEDP-RRPLPWALSAHPKR 397
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 398 REEDVRPIFWAS 409
Score = 24.6 bits (52), Expect(2) = 7e-08
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 326 PIKDNDAAIRNYG 338
[51][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 55.5 bits (132), Expect(2) = 7e-08
Identities = 32/66 (48%), Positives = 41/66 (62%), Gaps = 1/66 (1%)
Frame = +3
Query: 60 MCKKILAHG-LTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFRTREDVR 236
MCK +LA G ++ LH YTLN + + + +L LGL E R LPW A+ R EDVR
Sbjct: 305 MCKVLLASGEVSGLHFYTLNREVATMEVLRQLGLWAEDP-RRPLPWAISAHPKRKVEDVR 363
Query: 237 PIFWAN 254
PIFWA+
Sbjct: 364 PIFWAS 369
Score = 24.6 bits (52), Expect(2) = 7e-08
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 286 PIKDNDAAIRNYG 298
[52][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 55.1 bits (131), Expect(2) = 8e-08
Identities = 30/72 (41%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I + +C+++L GL LH YTLN + + + +L LG+ E R LPW A+ R
Sbjct: 339 IELAVNLCRELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTEDP-RRPLPWAVSAHPKR 397
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 398 REEDVRPIFWAS 409
Score = 24.6 bits (52), Expect(2) = 8e-08
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 326 PIKDNDAAIRNYG 338
[53][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 55.1 bits (131), Expect(2) = 8e-08
Identities = 30/72 (41%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I + +C+++L GL LH YTLN + + + +L LG+ E R LPW A+ R
Sbjct: 304 IELAVNLCRELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTEDP-RRPLPWAVSAHPKR 362
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 363 REEDVRPIFWAS 374
Score = 24.6 bits (52), Expect(2) = 8e-08
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 291 PIKDNDAAIRNYG 303
[54][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TTE9_VANPO
Length = 612
Score = 59.7 bits (143), Expect = 1e-07
Identities = 32/87 (36%), Positives = 50/87 (57%), Gaps = 12/87 (13%)
Frame = +3
Query: 24 LLKPMEIPVTTGMCKKILAHGLTS-LHLYTLNVD*SAIGILMNLGLIDESTISRSL---- 188
L++ + + MC+++L G+ S LHLYT+N++ + IL LGL+ E++ +S+
Sbjct: 242 LVREIGTQLVVDMCRRLLESGVVSHLHLYTMNLERPPLVILERLGLLPEASAEQSIDTFT 301
Query: 189 -------PWRRPANGFRTREDVRPIFW 248
PWRR N R E+VRPIFW
Sbjct: 302 NEPPAVVPWRRSLNPQRRNEEVRPIFW 328
[55][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 54.3 bits (129), Expect(2) = 1e-07
Identities = 31/71 (43%), Positives = 40/71 (56%), Gaps = 1/71 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I +C+++LA GL LH YTLN + + +L LG+ E R LPW A+ R
Sbjct: 298 IDQAVSLCQQLLASGLVPGLHFYTLNREVATTEVLKRLGMWVEDP-RRPLPWALSAHPKR 356
Query: 219 TREDVRPIFWA 251
EDVRPIFWA
Sbjct: 357 REEDVRPIFWA 367
Score = 25.0 bits (53), Expect(2) = 1e-07
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 285 PIKDNDGAIRNYG 297
[56][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 54.7 bits (130), Expect(2) = 1e-07
Identities = 30/72 (41%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I + +C+++L GL LH YTLN + + + +L LG+ E R LPW A+ R
Sbjct: 298 IELAVRLCRELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTEDP-RRPLPWALSAHPKR 356
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 357 REEDVRPIFWAS 368
Score = 24.6 bits (52), Expect(2) = 1e-07
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 285 PIKDNDAAIRNYG 297
[57][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 54.7 bits (130), Expect(2) = 1e-07
Identities = 30/72 (41%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
+ + MC+++L G+ LH YTLN + + +L LGL +E R LPW A+ R
Sbjct: 301 VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWNEDP-RRPLPWAVSAHPKR 359
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 360 RVEDVRPIFWAS 371
Score = 24.6 bits (52), Expect(2) = 1e-07
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 288 PIKDNDAAIRNYG 300
[58][TOP]
>UniRef100_UPI0000ECA34F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Gallus
gallus RepID=UPI0000ECA34F
Length = 640
Score = 54.7 bits (130), Expect(2) = 1e-07
Identities = 30/72 (41%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
+ + MC+++L GL LH YTLN + + +L LG+ +E R LPW A+ R
Sbjct: 289 VELAVSMCRELLDSGLVHGLHFYTLNREVATTEVLKRLGIWNEDP-RRPLPWAVSAHPKR 347
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 348 RVEDVRPIFWAS 359
Score = 24.6 bits (52), Expect(2) = 1e-07
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 276 PIKDNDAAIRNYG 288
[59][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
RepID=UPI0000E814FF
Length = 508
Score = 54.7 bits (130), Expect(2) = 1e-07
Identities = 30/72 (41%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
+ + MC+++L GL LH YTLN + + +L LG+ +E R LPW A+ R
Sbjct: 157 VELAVSMCRELLDSGLVHGLHFYTLNREVATTEVLKRLGIWNEDP-RRPLPWAVSAHPKR 215
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 216 RVEDVRPIFWAS 227
Score = 24.6 bits (52), Expect(2) = 1e-07
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 144 PIKDNDAAIRNYG 156
[60][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 59.3 bits (142), Expect = 1e-07
Identities = 30/67 (44%), Positives = 41/67 (61%), Gaps = 2/67 (2%)
Frame = +3
Query: 60 MCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLI--DESTISRSLPWRRPANGFRTREDV 233
MC+++LA G+ LH YT+N+ + +L L LI +E+ + R LPWR R EDV
Sbjct: 261 MCRRLLAAGINHLHFYTMNLAQATQAVLEELKLIPSEETPLQRPLPWRPSLALNRRGEDV 320
Query: 234 RPIFWAN 254
RPIFW N
Sbjct: 321 RPIFWRN 327
[61][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 59.3 bits (142), Expect = 1e-07
Identities = 30/67 (44%), Positives = 41/67 (61%), Gaps = 2/67 (2%)
Frame = +3
Query: 60 MCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLI--DESTISRSLPWRRPANGFRTREDV 233
MC+++LA G+ LH YT+N+ + +L L LI +E+ + R LPWR R EDV
Sbjct: 261 MCRRLLAAGINHLHFYTMNLAQATQAVLEELKLIPSEETPLQRPLPWRPSLALNRRGEDV 320
Query: 234 RPIFWAN 254
RPIFW N
Sbjct: 321 RPIFWRN 327
[62][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 59.3 bits (142), Expect = 1e-07
Identities = 29/67 (43%), Positives = 42/67 (62%), Gaps = 2/67 (2%)
Frame = +3
Query: 60 MCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLI--DESTISRSLPWRRPANGFRTREDV 233
MC++++A G+ LH YT+N+ S +L L L+ +E+ + R+LPWR R EDV
Sbjct: 261 MCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETPLQRALPWRPSLGLNRRAEDV 320
Query: 234 RPIFWAN 254
RPIFW N
Sbjct: 321 RPIFWRN 327
[63][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 58.2 bits (139), Expect(2) = 1e-07
Identities = 32/72 (44%), Positives = 45/72 (62%), Gaps = 9/72 (12%)
Frame = +3
Query: 60 MCKKILAHG-LTSLHLYTLNVD*SAIGILMNLGLIDES--------TISRSLPWRRPANG 212
MC+KILA G +T LHLYT+N++ +++ IL L LID + + +L WR+ N
Sbjct: 264 MCRKILASGHVTHLHLYTMNLERASLMILERLQLIDTGGAGVRRRPSTNETLTWRKSLNP 323
Query: 213 FRTREDVRPIFW 248
R +E VRPIFW
Sbjct: 324 TRRKEGVRPIFW 335
Score = 20.8 bits (42), Expect(2) = 1e-07
Identities = 7/13 (53%), Positives = 10/13 (76%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
P+KD+D AV+ G
Sbjct: 245 PVKDDDQAVREIG 257
[64][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 58.9 bits (141), Expect = 2e-07
Identities = 30/67 (44%), Positives = 41/67 (61%), Gaps = 2/67 (2%)
Frame = +3
Query: 60 MCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLI--DESTISRSLPWRRPANGFRTREDV 233
MC+++LA G+ LH YT+N+ + +L L LI +E+ + R LPWR R EDV
Sbjct: 261 MCRRLLAAGIKHLHFYTMNLAQATQAVLEELKLIPSEETPLQRPLPWRPSLALNRRGEDV 320
Query: 234 RPIFWAN 254
RPIFW N
Sbjct: 321 RPIFWRN 327
[65][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 58.5 bits (140), Expect = 2e-07
Identities = 28/70 (40%), Positives = 42/70 (60%), Gaps = 5/70 (7%)
Frame = +3
Query: 60 MCKKILAHGLTS-LHLYTLNVD*SAIGILMNLGLI----DESTISRSLPWRRPANGFRTR 224
MC+K++ G + LH YT+N++ S + IL L L+ D + LPWR+ N R++
Sbjct: 264 MCQKLIDSGYVNHLHFYTMNLERSTVMILEKLNLVESIKDNDAVVEILPWRKSLNPSRSK 323
Query: 225 EDVRPIFWAN 254
E +RPIFW N
Sbjct: 324 ESIRPIFWQN 333
[66][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 58.5 bits (140), Expect = 2e-07
Identities = 30/67 (44%), Positives = 41/67 (61%), Gaps = 2/67 (2%)
Frame = +3
Query: 60 MCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLI--DESTISRSLPWRRPANGFRTREDV 233
MC+++LA G+ LH YT+N+ + +L L L+ +E+ I R LPWR R EDV
Sbjct: 261 MCRRLLAAGINHLHFYTMNLAQATQLVLDELKLLPSEETPIQRPLPWRPSLGLNRRAEDV 320
Query: 234 RPIFWAN 254
RPIFW N
Sbjct: 321 RPIFWRN 327
[67][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 58.2 bits (139), Expect = 3e-07
Identities = 34/67 (50%), Positives = 41/67 (61%), Gaps = 2/67 (2%)
Frame = +3
Query: 60 MCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGL-IDESTISRSLPWRRPANGFRTREDV 233
MC+++L GL LH YTLN + + IL LGL + SR LPWR AN R EDV
Sbjct: 248 MCRELLDSGLVPGLHFYTLNREVATREILTALGLWCMDPAASRPLPWRASANQKRFTEDV 307
Query: 234 RPIFWAN 254
RPIFWA+
Sbjct: 308 RPIFWAS 314
[68][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 58.2 bits (139), Expect = 3e-07
Identities = 30/65 (46%), Positives = 39/65 (60%), Gaps = 2/65 (3%)
Frame = +3
Query: 60 MCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLI--DESTISRSLPWRRPANGFRTREDV 233
MC+KIL G+ LH YT+N+ S +L L LI E+ + + LPWR+ R EDV
Sbjct: 261 MCRKILDSGIRHLHFYTMNLAQSTKMVLEELDLIPSSETPLQKPLPWRQSLGLGRREEDV 320
Query: 234 RPIFW 248
RPIFW
Sbjct: 321 RPIFW 325
[69][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 57.8 bits (138), Expect = 4e-07
Identities = 28/65 (43%), Positives = 40/65 (61%), Gaps = 2/65 (3%)
Frame = +3
Query: 60 MCKKILAHGLTSLHLYTLNVD*SAIGIL--MNLGLIDESTISRSLPWRRPANGFRTREDV 233
MC+K+L +G+ LH YT+N+ S +L +NL E+ + + LPWR+ R EDV
Sbjct: 261 MCRKLLDNGINHLHFYTMNLAQSTTMVLEELNLKPSTETPLQKPLPWRKSLGLGRREEDV 320
Query: 234 RPIFW 248
RPIFW
Sbjct: 321 RPIFW 325
[70][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Canis lupus familiaris RepID=UPI00005A03BF
Length = 780
Score = 52.8 bits (125), Expect(2) = 4e-07
Identities = 30/72 (41%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I +C+++L GL LH YTLN + + +L LG+ E R LPW A+ R
Sbjct: 424 IEQAVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDP-RRPLPWAVSAHPKR 482
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 483 REEDVRPIFWAS 494
Score = 24.6 bits (52), Expect(2) = 4e-07
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 411 PIKDNDAAIRNYG 423
[71][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 52.8 bits (125), Expect(2) = 4e-07
Identities = 30/72 (41%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHGLT-SLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I +C+++L GL LH YTLN + + +L LG+ E R LPW A+ R
Sbjct: 340 IEQAVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDP-RRPLPWAVSAHPKR 398
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 399 REEDVRPIFWAS 410
Score = 24.6 bits (52), Expect(2) = 4e-07
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 327 PIKDNDAAIRNYG 339
[72][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
RepID=A8PV87_BRUMA
Length = 656
Score = 54.7 bits (130), Expect(2) = 4e-07
Identities = 31/67 (46%), Positives = 46/67 (68%), Gaps = 3/67 (4%)
Frame = +3
Query: 60 MCKKILAHG-LTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWR--RPANGFRTRED 230
+C+ +L++G TS+HL+TLN + S+ IL LGL S + R+LPWR ++ R +ED
Sbjct: 316 LCRTLLSNGSATSIHLFTLNREASSREILQQLGLWPRSPM-RALPWRLFGESHPVRCKED 374
Query: 231 VRPIFWA 251
VRPIFW+
Sbjct: 375 VRPIFWS 381
Score = 22.7 bits (47), Expect(2) = 4e-07
Identities = 8/13 (61%), Positives = 12/13 (92%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIK++DDAV+ +G
Sbjct: 297 PIKNDDDAVRNFG 309
[73][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 57.4 bits (137), Expect = 5e-07
Identities = 29/67 (43%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Frame = +3
Query: 60 MCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLI--DESTISRSLPWRRPANGFRTREDV 233
MC+++LA G+ LH YT+N+ S +L L L +E+ + + LPWR R EDV
Sbjct: 261 MCRRLLAAGINHLHFYTMNLAQSTQLVLEELNLTPSEETPLQKPLPWRPSLGLNRRGEDV 320
Query: 234 RPIFWAN 254
RPIFW N
Sbjct: 321 RPIFWRN 327
[74][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 54.3 bits (129), Expect(2) = 5e-07
Identities = 27/72 (37%), Positives = 43/72 (59%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHG-LTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
+ + MC+++L+ + +H+YTLN + + +L LGL R LPW+ AN R
Sbjct: 276 VKLAVSMCRELLSSDDVPGIHVYTLNREVATTELLQQLGLWRPYQSHRLLPWKPSANLKR 335
Query: 219 TREDVRPIFWAN 254
+EDVRPIFW++
Sbjct: 336 LQEDVRPIFWSS 347
Score = 22.7 bits (47), Expect(2) = 5e-07
Identities = 7/13 (53%), Positives = 12/13 (92%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIK++D+A++ YG
Sbjct: 263 PIKNDDEAIREYG 275
[75][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 52.4 bits (124), Expect(2) = 5e-07
Identities = 31/72 (43%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHG-LTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I + MC+ +L G + LH YTLN + + + +L LGL E R LPW A+ R
Sbjct: 303 IQLAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWTEDP-RRPLPWAVSAHPKR 361
Query: 219 TREDVRPIFWAN 254
EDVRPIFWA+
Sbjct: 362 KVEDVRPIFWAS 373
Score = 24.6 bits (52), Expect(2) = 5e-07
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 290 PIKDNDAAIRNYG 302
[76][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 57.0 bits (136), Expect = 6e-07
Identities = 30/67 (44%), Positives = 39/67 (58%), Gaps = 2/67 (2%)
Frame = +3
Query: 60 MCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLID--ESTISRSLPWRRPANGFRTREDV 233
MC++++A G+ LH YT+N+ S +L L L E+ I R LPWR R EDV
Sbjct: 261 MCRRLIASGIKHLHFYTMNLAQSTQLVLEELELTPTAEAPIPRPLPWRPSLGLNRREEDV 320
Query: 234 RPIFWAN 254
RPIFW N
Sbjct: 321 RPIFWRN 327
[77][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6H337_AJECH
Length = 524
Score = 57.0 bits (136), Expect = 6e-07
Identities = 29/69 (42%), Positives = 41/69 (59%), Gaps = 2/69 (2%)
Frame = +3
Query: 48 VTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLI--DESTISRSLPWRRPANGFRT 221
+ MC+KILA G+ LH YT+N+ + +L L LI ++ + + LPWR+ R
Sbjct: 148 LVANMCRKILAAGIYHLHFYTMNLQQATKMVLGELELIPSHKTPLQKPLPWRQSLGLGRR 207
Query: 222 REDVRPIFW 248
EDVRPIFW
Sbjct: 208 EEDVRPIFW 216
[78][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 57.0 bits (136), Expect = 6e-07
Identities = 29/69 (42%), Positives = 41/69 (59%), Gaps = 2/69 (2%)
Frame = +3
Query: 48 VTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLI--DESTISRSLPWRRPANGFRT 221
+ MC+KILA G+ LH YT+N+ + +L L LI ++ + + LPWR+ R
Sbjct: 257 LVANMCRKILAAGIYHLHFYTMNLQQATKMVLGELELIPSHKTPLQKPLPWRQSLGLGRR 316
Query: 222 REDVRPIFW 248
EDVRPIFW
Sbjct: 317 EEDVRPIFW 325
[79][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 56.6 bits (135), Expect = 8e-07
Identities = 32/69 (46%), Positives = 44/69 (63%), Gaps = 6/69 (8%)
Frame = +3
Query: 60 MCKKILAHGLTS-LHLYTLNVD*SAIGILMNLGLI-DESTISR----SLPWRRPANGFRT 221
MC+KIL G LH+YT+N++ + + IL LGL+ ES ++ SLPWR+ N R
Sbjct: 266 MCQKILNSGYVKHLHIYTMNLEKAPLIILEKLGLLPSESEVNANPLASLPWRKSLNPKRK 325
Query: 222 REDVRPIFW 248
E+VRPIFW
Sbjct: 326 NEEVRPIFW 334
[80][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 56.6 bits (135), Expect = 8e-07
Identities = 28/67 (41%), Positives = 41/67 (61%), Gaps = 2/67 (2%)
Frame = +3
Query: 60 MCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLID--ESTISRSLPWRRPANGFRTREDV 233
MC+K++A G+T LH YT+N+ + +L L L+ E+ + + LPWR R E+V
Sbjct: 261 MCRKLIAAGITHLHFYTMNLAQATRMVLEELDLLPDVEAPLEKPLPWRPSLGLNRRDENV 320
Query: 234 RPIFWAN 254
RPIFW N
Sbjct: 321 RPIFWRN 327
[81][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 56.2 bits (134), Expect = 1e-06
Identities = 30/83 (36%), Positives = 47/83 (56%), Gaps = 6/83 (7%)
Frame = +3
Query: 24 LLKPMEIPVTTGMCKKILAHG-LTSLHLYTLNVD*SAIGILMNLGLID-----ESTISRS 185
L++ + + MC+K+L G + LH YT+N++ + + IL L LI+ E
Sbjct: 249 LVREKGTELVSEMCQKLLESGYINHLHFYTMNLEKATVMILEKLNLIEAVKSNEIVGVTE 308
Query: 186 LPWRRPANGFRTREDVRPIFWAN 254
LPWR+ N R++E +RPIFW N
Sbjct: 309 LPWRKSLNPERSKESIRPIFWQN 331
[82][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 56.2 bits (134), Expect = 1e-06
Identities = 31/68 (45%), Positives = 42/68 (61%), Gaps = 3/68 (4%)
Frame = +3
Query: 60 MCKKILAHG-LTSLHLYTLNVD*SAIGILMNLGLI--DESTISRSLPWRRPANGFRTRED 230
MC+K+LA G + LH YT+N+ + IL L L+ +E+ + + LPWRR R ED
Sbjct: 261 MCRKLLASGHIHHLHFYTMNLAQATRLILEELRLLPSEEAPLQKPLPWRRSLGLRRRSED 320
Query: 231 VRPIFWAN 254
VRPIFW N
Sbjct: 321 VRPIFWRN 328
[83][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 56.2 bits (134), Expect = 1e-06
Identities = 28/67 (41%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Frame = +3
Query: 60 MCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLI--DESTISRSLPWRRPANGFRTREDV 233
MC++++A G+ LH YT+N+ + +L L L ++S I R LPWR R EDV
Sbjct: 261 MCRQLIAAGIKHLHFYTMNLAQATQLVLKELELTPSEDSPIQRPLPWRPSLGLGRRSEDV 320
Query: 234 RPIFWAN 254
RP+FW N
Sbjct: 321 RPVFWRN 327
[84][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 56.2 bits (134), Expect = 1e-06
Identities = 30/83 (36%), Positives = 48/83 (57%), Gaps = 6/83 (7%)
Frame = +3
Query: 24 LLKPMEIPVTTGMCKKILAHGLTS-LHLYTLNVD*SAIGILMNLGLID-----ESTISRS 185
L++ + + MC K+L G + LH YT+N++ + I IL L +I+ E+T
Sbjct: 249 LVREKGTELVSQMCTKLLQSGFVNHLHFYTMNLERATIMILETLNIIEPVKAHENTGGDE 308
Query: 186 LPWRRPANGFRTREDVRPIFWAN 254
LPWR+ + R++E +RPIFW N
Sbjct: 309 LPWRKSLHPQRSKETIRPIFWQN 331
[85][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 55.8 bits (133), Expect = 1e-06
Identities = 31/68 (45%), Positives = 42/68 (61%), Gaps = 3/68 (4%)
Frame = +3
Query: 60 MCKKILAHG-LTSLHLYTLNVD*SAIGILMNLGLI--DESTISRSLPWRRPANGFRTRED 230
MC+K+LA G + LH YT+N+ + IL L L+ +E+ + + LPWRR R ED
Sbjct: 261 MCRKLLASGQIHHLHFYTMNLAQATRLILEELRLLPSEEAPLHKPLPWRRSLGLRRRSED 320
Query: 231 VRPIFWAN 254
VRPIFW N
Sbjct: 321 VRPIFWRN 328
[86][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 55.8 bits (133), Expect = 1e-06
Identities = 28/69 (40%), Positives = 41/69 (59%), Gaps = 2/69 (2%)
Frame = +3
Query: 48 VTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLID--ESTISRSLPWRRPANGFRT 221
+ MC+K+LA G+ LH YT+N+ + +L L LI ++ + + LPWR+ R
Sbjct: 243 LVANMCRKMLAAGIHHLHFYTMNLQQATKMVLGELELIPSHKTPLQKPLPWRQSLGLGRR 302
Query: 222 REDVRPIFW 248
EDVRPIFW
Sbjct: 303 EEDVRPIFW 311
[87][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 55.5 bits (132), Expect = 2e-06
Identities = 30/83 (36%), Positives = 47/83 (56%), Gaps = 6/83 (7%)
Frame = +3
Query: 24 LLKPMEIPVTTGMCKKILAHGLTS-LHLYTLNVD*SAIGILMNLGLID-----ESTISRS 185
L++ + + MC K++ G + LH YT+N++ + I IL NL LI+ E
Sbjct: 249 LVRAKGTELVSEMCTKLIKSGYVNHLHFYTMNLERATIMILENLNLIESVKSHEVIGGSD 308
Query: 186 LPWRRPANGFRTREDVRPIFWAN 254
LPWR+ + R++E +RPIFW N
Sbjct: 309 LPWRKSLHPQRSKESIRPIFWQN 331
[88][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 55.5 bits (132), Expect = 2e-06
Identities = 29/69 (42%), Positives = 40/69 (57%), Gaps = 2/69 (2%)
Frame = +3
Query: 48 VTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLID--ESTISRSLPWRRPANGFRT 221
+ MC+KIL G+ LH YT+N+ + +L L LI E+ + + LPWR+ R
Sbjct: 257 LVANMCQKILDSGIRHLHFYTMNLAQATKMVLEELKLIPSYETPLQKPLPWRQSLGLGRR 316
Query: 222 REDVRPIFW 248
EDVRPIFW
Sbjct: 317 DEDVRPIFW 325
[89][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 55.5 bits (132), Expect = 2e-06
Identities = 29/69 (42%), Positives = 40/69 (57%), Gaps = 2/69 (2%)
Frame = +3
Query: 48 VTTGMCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLID--ESTISRSLPWRRPANGFRT 221
+ MC+KIL G+ LH YT+N+ + +L L LI E+ + + LPWR+ R
Sbjct: 257 LVANMCQKILDSGIRHLHFYTMNLAQATKMVLEELKLIPSYETPLQKPLPWRQSLGLGRR 316
Query: 222 REDVRPIFW 248
EDVRPIFW
Sbjct: 317 DEDVRPIFW 325
[90][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 55.5 bits (132), Expect = 2e-06
Identities = 30/83 (36%), Positives = 47/83 (56%), Gaps = 6/83 (7%)
Frame = +3
Query: 24 LLKPMEIPVTTGMCKKILAHGLTS-LHLYTLNVD*SAIGILMNLGLID-----ESTISRS 185
L++ + + MC K++ G + LH YT+N++ + I IL NL LI+ E
Sbjct: 249 LVRAKGTELVSEMCTKLIKSGYVNHLHFYTMNLERATIMILENLNLIESVKSHEVIGGSD 308
Query: 186 LPWRRPANGFRTREDVRPIFWAN 254
LPWR+ + R++E +RPIFW N
Sbjct: 309 LPWRKSLHPQRSKESIRPIFWQN 331
[91][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 50.4 bits (119), Expect(2) = 2e-06
Identities = 30/72 (41%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHG-LTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I + MC+ +L G + LH YTLN + + + +L LGL E R LPW A+ R
Sbjct: 303 IQLAVQMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDP-RRPLPWAVSAHPKR 361
Query: 219 TREDVRPIFWAN 254
EDVRPIFW++
Sbjct: 362 KVEDVRPIFWSS 373
Score = 24.6 bits (52), Expect(2) = 2e-06
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 290 PIKDNDAAIRNYG 302
[92][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 50.4 bits (119), Expect(2) = 2e-06
Identities = 30/72 (41%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 IPVTTGMCKKILAHG-LTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFR 218
I + MC+ +L G + LH YTLN + + + +L LGL E R LPW A+ R
Sbjct: 303 IQLAVQMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDP-RRPLPWAVSAHPKR 361
Query: 219 TREDVRPIFWAN 254
EDVRPIFW++
Sbjct: 362 KVEDVRPIFWSS 373
Score = 24.6 bits (52), Expect(2) = 2e-06
Identities = 9/13 (69%), Positives = 11/13 (84%)
Frame = +2
Query: 2 PIKDNDDAVKAYG 40
PIKDND A++ YG
Sbjct: 290 PIKDNDAAIRNYG 302
[93][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 55.1 bits (131), Expect = 2e-06
Identities = 27/67 (40%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Frame = +3
Query: 60 MCKKILAHGLTSLHLYTLNVD*SAIGIL--MNLGLIDESTISRSLPWRRPANGFRTREDV 233
MC+K+LA+G+ LH YT+N+ + +L +N E + +LPW++ R EDV
Sbjct: 261 MCRKLLANGIHHLHFYTMNLAQATRMVLEELNWAPSAERPLQHALPWKQSKGLGRREEDV 320
Query: 234 RPIFWAN 254
RPIFW N
Sbjct: 321 RPIFWRN 327
[94][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 54.7 bits (130), Expect = 3e-06
Identities = 26/67 (38%), Positives = 38/67 (56%), Gaps = 2/67 (2%)
Frame = +3
Query: 60 MCKKILAH--GLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFRTREDV 233
MC++IL G+ LH YT+N++ +L L L+ + LPWR+ R +E +
Sbjct: 262 MCRRILKEDIGIRGLHFYTMNLEKGTKMLLEELNLVPRIETIKPLPWRQSLTPNRRQESI 321
Query: 234 RPIFWAN 254
RPIFWAN
Sbjct: 322 RPIFWAN 328
[95][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 54.7 bits (130), Expect = 3e-06
Identities = 28/67 (41%), Positives = 39/67 (58%), Gaps = 2/67 (2%)
Frame = +3
Query: 60 MCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDEST--ISRSLPWRRPANGFRTREDV 233
+C+KILA G+ LH YT+N+ S IL +L + + +LPW++ R EDV
Sbjct: 256 LCRKILAAGIHHLHFYTMNLAQSTALILEDLDWLPSPNKPLKHALPWKQSLGLGRREEDV 315
Query: 234 RPIFWAN 254
RPIFW N
Sbjct: 316 RPIFWRN 322
[96][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 54.3 bits (129), Expect = 4e-06
Identities = 34/91 (37%), Positives = 50/91 (54%), Gaps = 8/91 (8%)
Frame = +3
Query: 6 LRIMTMLLKPMEIPVTTGMCKKILAHGLT----SLHLYTLNVD*SAIGILMNLGLIDEST 173
+R+ +K + + MC++IL+ GL H YTLN++ S IL +LG S
Sbjct: 234 IRLDDEAVKQVGCKIVAEMCEQILSAGLEVDVDGFHFYTLNLERSTTRILTSLGAGSISE 293
Query: 174 ISRS----LPWRRPANGFRTREDVRPIFWAN 254
+RS LPW+ A R++EDVRPI W+N
Sbjct: 294 QARSTRRVLPWKPSAMENRSKEDVRPINWSN 324
[97][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S5W8_NEMVE
Length = 619
Score = 54.3 bits (129), Expect = 4e-06
Identities = 29/68 (42%), Positives = 45/68 (66%), Gaps = 1/68 (1%)
Frame = +3
Query: 54 TGMCKKILAHG-LTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFRTRED 230
T MC+++ A G + +HLYTLN++ + IL NL + E +++ LPW+ + R+ ED
Sbjct: 279 TKMCQELFASGKVQGIHLYTLNIEKPVMSILENLKISKEPELNK-LPWQ--LSDVRSGED 335
Query: 231 VRPIFWAN 254
VRPIFWA+
Sbjct: 336 VRPIFWAS 343
[98][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 54.3 bits (129), Expect = 4e-06
Identities = 28/67 (41%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Frame = +3
Query: 60 MCKKILAHGL--TSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFRTREDV 233
MC+KIL GL LH YT+N++ +L L L+ + LPWR+ R E +
Sbjct: 222 MCRKILDSGLGIRGLHFYTMNLEKGTRMLLEELNLVPRIETIKPLPWRQCLTPNRRNETI 281
Query: 234 RPIFWAN 254
RPIFWAN
Sbjct: 282 RPIFWAN 288
[99][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 50.4 bits (119), Expect(2) = 4e-06
Identities = 35/88 (39%), Positives = 49/88 (55%), Gaps = 12/88 (13%)
Frame = +3
Query: 27 LKPMEIPVTTGMCKKILAHGLTSL---HLYTLNVD*SAIGILM------NLGLIDE--ST 173
+K + + MC++ILA + + H YTLN++ SA ILM N GL+D+ +
Sbjct: 276 VKEIGCSLAAEMCRQILADPIAKIDGVHFYTLNLERSATRILMQLDGTVNSGLVDKIRTK 335
Query: 174 ISRSLPWRRPANGFRTR-EDVRPIFWAN 254
R LPWR A R++ E VRPI WAN
Sbjct: 336 SGRILPWRPSAMTGRSKMEQVRPINWAN 363
Score = 23.5 bits (49), Expect(2) = 4e-06
Identities = 10/15 (66%), Positives = 12/15 (80%)
Frame = +2
Query: 2 PIKDNDDAVKAYGNS 46
PIKD+D+AVK G S
Sbjct: 268 PIKDDDEAVKEIGCS 282
[100][TOP]
>UniRef100_UPI000151BABB hypothetical protein PGUG_04648 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151BABB
Length = 355
Score = 53.9 bits (128), Expect = 5e-06
Identities = 29/71 (40%), Positives = 43/71 (60%), Gaps = 6/71 (8%)
Frame = +3
Query: 60 MCKKILAHGLTS-LHLYTLNVD*SAIGILMNLGLID-----ESTISRSLPWRRPANGFRT 221
MC+K++ + S LH YT+N++ + I IL NL LI+ E LPWR+ + R+
Sbjct: 1 MCQKLIDSKVVSHLHFYTMNLERATIMILENLNLIEPVKDHEIIGGVDLPWRKSLHPSRS 60
Query: 222 REDVRPIFWAN 254
+E +RPIFW N
Sbjct: 61 KESIRPIFWQN 71
[101][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 53.9 bits (128), Expect = 5e-06
Identities = 30/69 (43%), Positives = 43/69 (62%), Gaps = 6/69 (8%)
Frame = +3
Query: 60 MCKKILAHG-LTSLHLYTLNVD*SAIGILMNLGLIDEST-ISRS----LPWRRPANGFRT 221
MC+K+L G +T LH+YT+N++ + I +L LGL+ E I R +PWR+ + R
Sbjct: 264 MCQKLLDSGYVTHLHMYTMNLEKACIMVLDRLGLLSEDEDIFRDEVVPMPWRKSLHPQRR 323
Query: 222 REDVRPIFW 248
E VRPIFW
Sbjct: 324 NESVRPIFW 332
[102][TOP]
>UniRef100_A8Q9P3 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8Q9P3_MALGO
Length = 515
Score = 53.9 bits (128), Expect = 5e-06
Identities = 28/68 (41%), Positives = 38/68 (55%), Gaps = 3/68 (4%)
Frame = +3
Query: 60 MCKKILAH---GLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFRTRED 230
MCKKIL H + +H+YT+N++ + +L LGL LPWR R E+
Sbjct: 186 MCKKILEHPDLDIHGVHIYTMNLERGSRMLLEYLGLTPSVQQLHPLPWRPSLTPKRREEN 245
Query: 231 VRPIFWAN 254
+RPIFWAN
Sbjct: 246 IRPIFWAN 253
[103][TOP]
>UniRef100_A5DMZ7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DMZ7_PICGU
Length = 355
Score = 53.9 bits (128), Expect = 5e-06
Identities = 29/71 (40%), Positives = 43/71 (60%), Gaps = 6/71 (8%)
Frame = +3
Query: 60 MCKKILAHGLTS-LHLYTLNVD*SAIGILMNLGLID-----ESTISRSLPWRRPANGFRT 221
MC+K++ + S LH YT+N++ + I IL NL LI+ E LPWR+ + R+
Sbjct: 1 MCQKLIDSKVVSHLHFYTMNLERATIMILENLNLIEPVKDHEIIGGVDLPWRKSLHPSRS 60
Query: 222 REDVRPIFWAN 254
+E +RPIFW N
Sbjct: 61 KESIRPIFWQN 71
[104][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 53.5 bits (127), Expect = 7e-06
Identities = 26/67 (38%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Frame = +3
Query: 60 MCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDE--STISRSLPWRRPANGFRTREDV 233
MC++++ G+T LH YT+N+ + +L L L+ + S + + LPWR R E+V
Sbjct: 261 MCRRLIEAGITHLHFYTMNLAQATRMVLEELDLLPDPGSPLEKPLPWRPSLGLNRRDENV 320
Query: 234 RPIFWAN 254
RPIFW N
Sbjct: 321 RPIFWRN 327
[105][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 53.5 bits (127), Expect = 7e-06
Identities = 27/67 (40%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Frame = +3
Query: 60 MCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLID--ESTISRSLPWRRPANGFRTREDV 233
+C+KILA G+ LH YT+N+ + +L L + + + ++LPW+R R EDV
Sbjct: 261 LCRKILAAGIHHLHFYTMNLAQATRMVLEELDWMPSPDRPVKQALPWKRSLGLGRQVEDV 320
Query: 234 RPIFWAN 254
RPIFW N
Sbjct: 321 RPIFWRN 327
[106][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 53.1 bits (126), Expect = 9e-06
Identities = 26/67 (38%), Positives = 38/67 (56%), Gaps = 2/67 (2%)
Frame = +3
Query: 60 MCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLIDEST--ISRSLPWRRPANGFRTREDV 233
MC+KI+ G+ LH YT+N+ + +L L + + R+LPW++ R EDV
Sbjct: 261 MCRKIVDAGIRHLHFYTMNLAQATRMVLEELDWLPSPNRPLKRALPWKQSLGSGRRDEDV 320
Query: 234 RPIFWAN 254
RPIFW N
Sbjct: 321 RPIFWRN 327
[107][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 53.1 bits (126), Expect = 9e-06
Identities = 29/68 (42%), Positives = 36/68 (52%), Gaps = 3/68 (4%)
Frame = +3
Query: 60 MCKKILAH---GLTSLHLYTLNVD*SAIGILMNLGLIDESTISRSLPWRRPANGFRTRED 230
MCK IL + G+ LH+YTLN++ A +L LG LPWR R E
Sbjct: 265 MCKTILDNKEAGIKGLHIYTLNLEKGARMLLRELGFEGRREQIAPLPWRPSLTPSRREET 324
Query: 231 VRPIFWAN 254
+RPIFWAN
Sbjct: 325 IRPIFWAN 332
[108][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 53.1 bits (126), Expect = 9e-06
Identities = 26/67 (38%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Frame = +3
Query: 60 MCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLID--ESTISRSLPWRRPANGFRTREDV 233
MC+KIL+ G+ LH YT+N+ + +L L + + + ++LPW++ R EDV
Sbjct: 261 MCRKILSAGIRHLHFYTMNLAQATRMVLEELDWLPSPDRPLKQALPWKQSLGFGRRDEDV 320
Query: 234 RPIFWAN 254
RPIFW N
Sbjct: 321 RPIFWRN 327
[109][TOP]
>UniRef100_A6SLU6 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6SLU6_BOTFB
Length = 390
Score = 53.1 bits (126), Expect = 9e-06
Identities = 26/67 (38%), Positives = 39/67 (58%), Gaps = 2/67 (2%)
Frame = +3
Query: 60 MCKKILAHGLTSLHLYTLNVD*SAIGILMNLGLI--DESTISRSLPWRRPANGFRTREDV 233
MC++I+ G+ LH YT+N+ + +L L L ++ + +LPWR+ R EDV
Sbjct: 261 MCRRIIEAGVHHLHFYTMNLAQATRMVLEELSLTPSNQRPLKHALPWRQSLGLGRREEDV 320
Query: 234 RPIFWAN 254
RPIFW N
Sbjct: 321 RPIFWKN 327