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[1][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=B9DHL6_ARATH
Length = 402
Score = 275 bits (703), Expect = 2e-72
Identities = 132/132 (100%), Positives = 132/132 (100%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF
Sbjct: 271 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 330
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN
Sbjct: 331 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 390
Query: 199 NYINGDIFSVFA 164
NYINGDIFSVFA
Sbjct: 391 NYINGDIFSVFA 402
[2][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 275 bits (703), Expect = 2e-72
Identities = 132/132 (100%), Positives = 132/132 (100%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF
Sbjct: 461 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 520
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN
Sbjct: 521 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 580
Query: 199 NYINGDIFSVFA 164
NYINGDIFSVFA
Sbjct: 581 NYINGDIFSVFA 592
[3][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 241 bits (616), Expect = 2e-62
Identities = 113/131 (86%), Positives = 121/131 (92%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLEFFCSK+KLD +VEK KA PSITYMAVNK E WVSNT ++DVNAVTWGVFP
Sbjct: 462 GYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQADVNAVTWGVFP 521
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
AKE+IQPTIVDPASF VWKDEAFE WSRSWANLYPE DPSR LLEEVKNSYYLVSLV+N+
Sbjct: 522 AKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVKNSYYLVSLVEND 581
Query: 196 YINGDIFSVFA 164
YINGDIF+VFA
Sbjct: 582 YINGDIFAVFA 592
[4][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 227 bits (578), Expect = 5e-58
Identities = 103/132 (78%), Positives = 119/132 (90%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GGYVYQKAYLEFFCSK+KL+ LVE+ KAFP +TYMAVN+ +W+SN +DVNAVTWGVF
Sbjct: 475 GGYVYQKAYLEFFCSKEKLNALVERCKAFPLVTYMAVNRGGSWISNVALTDVNAVTWGVF 534
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
PAKE+IQPT+VDP SF VWKDEAFEIWSR WA+LYPE DPSR LLEEV+NSY+LVSLVDN
Sbjct: 535 PAKEIIQPTVVDPTSFSVWKDEAFEIWSRGWASLYPEGDPSRTLLEEVQNSYFLVSLVDN 594
Query: 199 NYINGDIFSVFA 164
+YI+GDIF+VFA
Sbjct: 595 DYIHGDIFAVFA 606
[5][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 224 bits (571), Expect = 3e-57
Identities = 100/131 (76%), Positives = 118/131 (90%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GGYVYQKAYLEFFCS++KL+ LV+K K PS+TYMAVNK W+SN G +VNAVTWGVF
Sbjct: 461 GGYVYQKAYLEFFCSREKLNALVDKCKGHPSLTYMAVNKEGTWMSNVGPGEVNAVTWGVF 520
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
PA+E+IQPT+VDP+SF VWKDEAFEIWSR WA LYPEDDPSRKLLEEV+NS++LVSLVDN
Sbjct: 521 PAREIIQPTVVDPSSFMVWKDEAFEIWSRGWALLYPEDDPSRKLLEEVQNSHFLVSLVDN 580
Query: 199 NYINGDIFSVF 167
+YINGD+F++F
Sbjct: 581 DYINGDLFAIF 591
[6][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 223 bits (569), Expect = 6e-57
Identities = 101/132 (76%), Positives = 118/132 (89%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GGYVYQKAYLEFFCSKDKL+ LV+K K+FP +TY+AVNK +W+SN +DVNAVTWGVF
Sbjct: 472 GGYVYQKAYLEFFCSKDKLNALVDKCKSFPFVTYIAVNKGGSWISNVALTDVNAVTWGVF 531
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
P KE+IQPT+VDP SF VWKDEAFEIWSR WA+LYPE DPSR LLEEV++SY+LVSLVDN
Sbjct: 532 PGKEIIQPTVVDPTSFSVWKDEAFEIWSRGWASLYPEGDPSRTLLEEVQSSYFLVSLVDN 591
Query: 199 NYINGDIFSVFA 164
+YI+GDIF+VFA
Sbjct: 592 DYIHGDIFAVFA 603
[7][TOP]
>UniRef100_A9P8D1 Putative uncharacterized protein n=1 Tax=Populus trichocarpa
RepID=A9P8D1_POPTR
Length = 224
Score = 223 bits (569), Expect = 6e-57
Identities = 101/132 (76%), Positives = 118/132 (89%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GGYVYQKAYLEFFCSKDKL+ LV+K K+FP +TY+AVNK +W+SN +DVNAVTWGVF
Sbjct: 91 GGYVYQKAYLEFFCSKDKLNALVDKCKSFPFVTYIAVNKGGSWISNVALTDVNAVTWGVF 150
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
P KE+IQPT+VDP SF VWKDEAFEIWSR WA+LYPE DPSR LLEEV++SY+LVSLVDN
Sbjct: 151 PGKEIIQPTVVDPTSFSVWKDEAFEIWSRGWASLYPEGDPSRTLLEEVQSSYFLVSLVDN 210
Query: 199 NYINGDIFSVFA 164
+YI+GDIF+VFA
Sbjct: 211 DYIHGDIFAVFA 222
[8][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 221 bits (563), Expect = 3e-56
Identities = 99/131 (75%), Positives = 117/131 (89%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GGYVYQKAYLEFFCS++KL+ LV+K K S+TYMAVNK W+SN G +VNAVTWGVF
Sbjct: 461 GGYVYQKAYLEFFCSREKLNALVDKCKGHTSLTYMAVNKEGTWMSNVGPGEVNAVTWGVF 520
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
PA+E+IQPT+VDP+SF VWKDEAFEIWSR WA LYPEDDPSRKLLEEV+NS++LVSLVDN
Sbjct: 521 PAREIIQPTVVDPSSFMVWKDEAFEIWSRGWALLYPEDDPSRKLLEEVQNSHFLVSLVDN 580
Query: 199 NYINGDIFSVF 167
+YINGD+F++F
Sbjct: 581 DYINGDLFAIF 591
[9][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 221 bits (563), Expect = 3e-56
Identities = 99/131 (75%), Positives = 117/131 (89%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GGYVYQKAYLEFFCS++KL+ LV+K K S+TYMAVNK W+SN G +VNAVTWGVF
Sbjct: 454 GGYVYQKAYLEFFCSREKLNALVDKCKGHTSLTYMAVNKEGTWMSNVGPGEVNAVTWGVF 513
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
PA+E+IQPT+VDP+SF VWKDEAFEIWSR WA LYPEDDPSRKLLEEV+NS++LVSLVDN
Sbjct: 514 PAREIIQPTVVDPSSFMVWKDEAFEIWSRGWALLYPEDDPSRKLLEEVQNSHFLVSLVDN 573
Query: 199 NYINGDIFSVF 167
+YINGD+F++F
Sbjct: 574 DYINGDLFAIF 584
[10][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 219 bits (558), Expect = 1e-55
Identities = 99/132 (75%), Positives = 116/132 (87%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GGYVYQKAY+EFFCS DKL L+EK KA P +TYMAVN+ +SN G++DVNAVTWGVF
Sbjct: 476 GGYVYQKAYIEFFCSTDKLQALLEKCKALPQLTYMAVNRGGTLLSNVGQNDVNAVTWGVF 535
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
P K++IQPT+VDPASF VWKDEAFEIW+R WA+LYPE DPSRKLLEEV++SY+LVSLVDN
Sbjct: 536 PGKQIIQPTVVDPASFSVWKDEAFEIWTRGWASLYPESDPSRKLLEEVQSSYFLVSLVDN 595
Query: 199 NYINGDIFSVFA 164
+YI GDIF+VFA
Sbjct: 596 DYIQGDIFAVFA 607
[11][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 205 bits (522), Expect = 2e-51
Identities = 94/131 (71%), Positives = 111/131 (84%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GGYVYQKAYLEFFC+K+KLD L+EK KAFPS+TY+AVNK SN + VNAVTWGVF
Sbjct: 461 GGYVYQKAYLEFFCAKEKLDQLIEKIKAFPSLTYIAVNKDGESFSNIAPNAVNAVTWGVF 520
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
P KE+IQPT+VDPASF VWKDEAFEIW+R WA L+PE D SR+LLE+V+ SYYLVSLVDN
Sbjct: 521 PGKEIIQPTVVDPASFMVWKDEAFEIWTRGWACLFPEGDSSRELLEKVQKSYYLVSLVDN 580
Query: 199 NYINGDIFSVF 167
+Y+ GD+F+ F
Sbjct: 581 DYVQGDLFAAF 591
[12][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 205 bits (522), Expect = 2e-51
Identities = 93/130 (71%), Positives = 112/130 (86%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAY+EFFCS +KL+ LVEK+K P +TY+AVNK +N G +DVNAVTWGVFP
Sbjct: 462 GYVYQKAYVEFFCSPEKLNELVEKAKNLPFVTYIAVNKKGATAANIGPTDVNAVTWGVFP 521
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
AKEVIQPT+VDP SF VWKDEAF+ W + WA+LYP+ DPSRK+LEEV+NSYYLVS+VDN+
Sbjct: 522 AKEVIQPTVVDPVSFMVWKDEAFQAWEQEWASLYPDGDPSRKILEEVQNSYYLVSVVDND 581
Query: 196 YINGDIFSVF 167
YI+GD+FSVF
Sbjct: 582 YIHGDLFSVF 591
[13][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 205 bits (522), Expect = 2e-51
Identities = 92/132 (69%), Positives = 111/132 (84%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GGYVYQKAY+EFFCS +KL ++EK+K PS+TY+AVN SN G + VNAVTWGVF
Sbjct: 461 GGYVYQKAYVEFFCSPEKLQAVIEKAKTSPSLTYIAVNAKGETKSNVGPTSVNAVTWGVF 520
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
PAKEVIQPT+VDP SF VWKDEAF+ W + WA+LYPEDD SRK+L E+K+SY+LVS+VDN
Sbjct: 521 PAKEVIQPTVVDPVSFMVWKDEAFQAWDQEWASLYPEDDASRKILSEIKSSYFLVSMVDN 580
Query: 199 NYINGDIFSVFA 164
+YINGD+FSVFA
Sbjct: 581 DYINGDLFSVFA 592
[14][TOP]
>UniRef100_A6N158 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Oryza sativa
Indica Group RepID=A6N158_ORYSI
Length = 237
Score = 204 bits (518), Expect = 5e-51
Identities = 93/131 (70%), Positives = 112/131 (85%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GGYVYQKAYLEFFCSK+KLD L+EKSKAFPS+TY+AVNK SN + VNAVTWGVF
Sbjct: 104 GGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVF 163
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
P KE++QPT+VD ASF VWKDEAFEIWS+ WA L+PE D SR++L++V+ SY+LVSLVDN
Sbjct: 164 PGKEIVQPTVVDSASFMVWKDEAFEIWSKGWACLFPEGDSSREILDKVQKSYFLVSLVDN 223
Query: 199 NYINGDIFSVF 167
+YINGD+F+ F
Sbjct: 224 DYINGDLFAAF 234
[15][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 204 bits (518), Expect = 5e-51
Identities = 93/131 (70%), Positives = 112/131 (85%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GGYVYQKAYLEFFCSK+KLD L+EKSKAFPS+TY+AVNK SN + VNAVTWGVF
Sbjct: 461 GGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVF 520
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
P KE++QPT+VD ASF VWKDEAFEIWS+ WA L+PE D SR++L++V+ SY+LVSLVDN
Sbjct: 521 PGKEIVQPTVVDSASFMVWKDEAFEIWSKGWACLFPEGDSSREILDKVQKSYFLVSLVDN 580
Query: 199 NYINGDIFSVF 167
+YINGD+F+ F
Sbjct: 581 DYINGDLFAAF 591
[16][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 203 bits (517), Expect = 6e-51
Identities = 93/131 (70%), Positives = 112/131 (85%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GGYVYQKAY+EFFC+K+KL L+EKSKAFPS+TY+AVNK +SN + VNAVTWGVF
Sbjct: 449 GGYVYQKAYVEFFCAKEKLGQLIEKSKAFPSLTYIAVNKEGESISNIPANAVNAVTWGVF 508
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
P KE+IQPT+VD ASF VWKDEAFEIWSR WA L+PE D SR+LLE+++ SYYLVSLVDN
Sbjct: 509 PGKEIIQPTVVDSASFMVWKDEAFEIWSRGWACLFPEGDSSRELLEQIQKSYYLVSLVDN 568
Query: 199 NYINGDIFSVF 167
+YI+GD+F+ F
Sbjct: 569 DYISGDLFAAF 579
[17][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 199 bits (505), Expect = 2e-49
Identities = 90/131 (68%), Positives = 109/131 (83%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GGYVYQKAYLEFFC+K+KLD L+EK KAFPS+TY+AVNK SN + VNAVTWGVF
Sbjct: 461 GGYVYQKAYLEFFCAKEKLDQLIEKIKAFPSLTYIAVNKDGETFSNISPNAVNAVTWGVF 520
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
P KE+IQPT+VD ASF VWKDEAFEIW+R W ++PE D SR+LLE+V+ +YYLVSLVDN
Sbjct: 521 PGKEIIQPTVVDHASFMVWKDEAFEIWTRGWGCMFPEGDSSRELLEKVQKTYYLVSLVDN 580
Query: 199 NYINGDIFSVF 167
+Y+ GD+F+ F
Sbjct: 581 DYVQGDLFAAF 591
[18][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 195 bits (495), Expect = 2e-48
Identities = 88/132 (66%), Positives = 109/132 (82%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GGYVYQKAY+EFFCS +KL ++EK+K+ PS+T++AVN SN G + VNAVTWGVF
Sbjct: 461 GGYVYQKAYVEFFCSPEKLQAVIEKAKSNPSLTFIAVNAKGETQSNIGPNCVNAVTWGVF 520
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
PAKEVIQPT+VDP SF VWKDEAF+ W WA LY E+D SRK+L E+K+SY+LVS+VDN
Sbjct: 521 PAKEVIQPTVVDPVSFMVWKDEAFQTWDHEWAALYSEEDSSRKILSEIKDSYFLVSMVDN 580
Query: 199 NYINGDIFSVFA 164
+YINGD+F+VFA
Sbjct: 581 DYINGDLFAVFA 592
[19][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 168 bits (426), Expect = 2e-40
Identities = 77/108 (71%), Positives = 91/108 (84%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GGYVYQKAYLEFFCSK+KLD L+EKSKAFPS+TY+AVNK SN + VNAVTWGVF
Sbjct: 461 GGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVF 520
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
P KE++QPT+VD ASF VWKDEAFEIWS+ WA L+PE D SR++L++V
Sbjct: 521 PGKEIVQPTVVDSASFMVWKDEAFEIWSKGWACLFPEGDSSREILDKV 568
[20][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 150 bits (380), Expect = 5e-35
Identities = 73/130 (56%), Positives = 89/130 (68%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GGYVY KAY+EFFCS + TL K A PSITY+A + + N VNAVTWGVF
Sbjct: 462 GGYVYGKAYVEFFCSPEAWATLRAKLDAAPSITYLATTAAGSPAGNMAPDAVNAVTWGVF 521
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
P KEVIQPT+V SF VWKDEAFE+W+ W LY E +R LL +K+S+ LVS+VDN
Sbjct: 522 PGKEVIQPTVVCAPSFAVWKDEAFELWTSEWGALYEEGSAARDLLAGIKDSWVLVSVVDN 581
Query: 199 NYINGDIFSV 170
+Y+ GD+F V
Sbjct: 582 DYVAGDLFGV 591
[21][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 145 bits (365), Expect = 3e-33
Identities = 68/130 (52%), Positives = 88/130 (67%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
G VY+KAY+EFF S + L+E K P ITY AVN+ + S T NAVTWG+FP
Sbjct: 470 GIVYKKAYIEFFASPENTLKLIEYFKKCPMITYHAVNRKGD--SKTNTKGTNAVTWGIFP 527
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
KE+IQPT+VD SF VWKDEAF +W W++ Y SR LL+ + N+YYL+++VDNN
Sbjct: 528 GKEIIQPTVVDHNSFMVWKDEAFALWETQWSSTYSPSSTSRTLLDSMINNYYLINIVDNN 587
Query: 196 YINGDIFSVF 167
+ING+IF F
Sbjct: 588 FINGNIFQSF 597
[22][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 144 bits (364), Expect = 3e-33
Identities = 62/127 (48%), Positives = 90/127 (70%), Gaps = 1/127 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENW-VSNTGESDVNAVTWGV 383
GGY+YQKAYLEFF S + + L+++ K +P + Y VN + ++N AVTWGV
Sbjct: 449 GGYIYQKAYLEFFASPEVVYILLQELKNYPQVNYHVVNNHDTVDITNCDSQTPVAVTWGV 508
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E++QPT+VDP SFK+WKDEAF +W + W+ LY ED SR ++ ++ N+Y LV+LVD
Sbjct: 509 FPGREIVQPTVVDPISFKIWKDEAFSLWEQQWSRLYTEDSKSRAIINKIMNTYCLVNLVD 568
Query: 202 NNYINGD 182
N++I G+
Sbjct: 569 NDFIKGN 575
[23][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 144 bits (362), Expect = 6e-33
Identities = 72/132 (54%), Positives = 91/132 (68%), Gaps = 1/132 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GGYVYQKAYLEFF S D L L+ + + P ITY AVNK + +NT NAVTWGVF
Sbjct: 456 GGYVYQKAYLEFFVSPDLLSPLIRRIEKDPRITYYAVNKQGDLRTNTHSESPNAVTWGVF 515
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
P KE++QPTIV+ SF WKDEAFE+ WA+LYP + PSRKL+ + N+ YLV++V N
Sbjct: 516 PGKEIVQPTIVEAVSFIAWKDEAFEL-GLQWAHLYPAESPSRKLITDTMNTSYLVNIVAN 574
Query: 199 NYING-DIFSVF 167
++ +G IF F
Sbjct: 575 DFRDGMSIFEPF 586
[24][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 143 bits (360), Expect = 1e-32
Identities = 66/125 (52%), Positives = 89/125 (71%), Gaps = 1/125 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENW-VSNTGESDVNAVTWGVF 380
GYVYQKAYLEFF S ++ TL+E FP I Y A++ SE+ VSN+ AVTWGVF
Sbjct: 489 GYVYQKAYLEFFISAERFKTLLEVLPNFPMINYHALDLSESINVSNSDHHQPIAVTWGVF 548
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
P +E++QPT+VDP SF WKDEAF +W+ WANLYPE+ SR+++ ++ LV++VDN
Sbjct: 549 PGREILQPTVVDPTSFSYWKDEAFALWTNQWANLYPEESKSRQVITAAVRNFVLVNMVDN 608
Query: 199 NYING 185
++I G
Sbjct: 609 DFIQG 613
[25][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 140 bits (354), Expect = 5e-32
Identities = 72/131 (54%), Positives = 90/131 (68%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLEFF S + LD L+ + +A P ITY AVN + +NT NAVTWGVFP
Sbjct: 469 GYVYQKAYLEFFVSPEDLDALIARIEADPQITYHAVNSQGDMRTNTNSEAPNAVTWGVFP 528
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
E+IQPTIV+ SF WKDEA+EI R+WA +Y PSRK LE++ NSY+LV++V N+
Sbjct: 529 HCEIIQPTIVESISFLAWKDEAYEI-GRNWAKVYEPTSPSRKFLEDMFNSYFLVNVVHND 587
Query: 196 Y-INGDIFSVF 167
+ N IF F
Sbjct: 588 FKANDSIFEPF 598
[26][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 138 bits (348), Expect = 2e-31
Identities = 59/123 (47%), Positives = 86/123 (69%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S + + L++ K + P + Y VN ++N + NAVTWG+
Sbjct: 504 GGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYQIVNVQGRNITNAHDMQPNAVTWGI 563
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+IQPT+VDP SF WKDEAF +W WA LY ++ PSR +++ + ++Y+LV+LVD
Sbjct: 564 FPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLVNLVD 623
Query: 202 NNY 194
N++
Sbjct: 624 NDF 626
[27][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 138 bits (347), Expect = 3e-31
Identities = 60/122 (49%), Positives = 85/122 (69%), Gaps = 1/122 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GYV+QKAYLEFF S + + L++ K + P + Y VN ++N + NAVTWG+F
Sbjct: 499 GYVFQKAYLEFFTSSEMVSALIKVLKRYEPRVNYHIVNVHGQNITNAADLQPNAVTWGIF 558
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
P +E+IQPT+VDP SF WKDEAF +W WA LY E+ PSR +++ + ++YYLV+LVDN
Sbjct: 559 PGREIIQPTVVDPVSFVYWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDN 618
Query: 199 NY 194
++
Sbjct: 619 DF 620
[28][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 136 bits (343), Expect = 9e-31
Identities = 60/128 (46%), Positives = 89/128 (69%), Gaps = 1/128 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVN-KSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S++ + L + +P++ Y + + ++ +N + AVTWGV
Sbjct: 493 GGYVFQKAYLEFFTSRENVQALFKVLPKYPNVNYHIIKFEGDDDYTNCDQQQPIAVTWGV 552
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP KE+IQPT+VDP SFK WKDEAF +W+ W LY ED SR+L++ + +++YLV+LVD
Sbjct: 553 FPGKEIIQPTVVDPVSFKFWKDEAFTLWTEYWGQLYAEDSKSRELIQHIHDTWYLVNLVD 612
Query: 202 NNYINGDI 179
N++ +I
Sbjct: 613 NDFPRDNI 620
[29][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 136 bits (342), Expect = 1e-30
Identities = 59/122 (48%), Positives = 85/122 (69%), Gaps = 1/122 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GYV+QKAYLEFF S + + L++ K + P + Y VN ++N + +AVTWG+F
Sbjct: 499 GYVFQKAYLEFFTSSEMVTALIKVLKRYEPRVNYHIVNVHGQNITNAADLQPSAVTWGIF 558
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
P +E+IQPT+VDP SF WKDEAF +W WA LY E+ PSR +++ + ++YYLV+LVDN
Sbjct: 559 PGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDN 618
Query: 199 NY 194
++
Sbjct: 619 DF 620
[30][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 135 bits (340), Expect = 2e-30
Identities = 59/123 (47%), Positives = 85/123 (69%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S++ + L++ K + + Y VN ++N E NAVTWG+
Sbjct: 527 GGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGI 586
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+IQPT+VDP SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV+LVD
Sbjct: 587 FPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYEEESPSRTIIQYIHDNYFLVNLVD 646
Query: 202 NNY 194
N++
Sbjct: 647 NDF 649
[31][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 135 bits (340), Expect = 2e-30
Identities = 59/123 (47%), Positives = 85/123 (69%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S++ + L++ K + + Y VN ++N E NAVTWG+
Sbjct: 545 GGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGI 604
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+IQPT+VDP SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV+LVD
Sbjct: 605 FPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYEEESPSRTIIQYIHDNYFLVNLVD 664
Query: 202 NNY 194
N++
Sbjct: 665 NDF 667
[32][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 135 bits (340), Expect = 2e-30
Identities = 59/123 (47%), Positives = 85/123 (69%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S++ + L++ K + + Y VN ++N E NAVTWG+
Sbjct: 527 GGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGI 586
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+IQPT+VDP SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV+LVD
Sbjct: 587 FPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYIHDNYFLVNLVD 646
Query: 202 NNY 194
N++
Sbjct: 647 NDF 649
[33][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 135 bits (340), Expect = 2e-30
Identities = 59/123 (47%), Positives = 85/123 (69%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S++ + L++ K + + Y VN ++N E NAVTWG+
Sbjct: 545 GGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGI 604
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+IQPT+VDP SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV+LVD
Sbjct: 605 FPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYIHDNYFLVNLVD 664
Query: 202 NNY 194
N++
Sbjct: 665 NDF 667
[34][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 135 bits (340), Expect = 2e-30
Identities = 65/134 (48%), Positives = 96/134 (71%), Gaps = 5/134 (3%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVE--KSKAFPSITYMAVNKSENWVSNT--GESDVNAVT 392
GG+VYQKAY+EFFC + +L+ L+ +++ + SI+YMAV + V + + VNAVT
Sbjct: 435 GGFVYQKAYVEFFCPEGQLEQLIRGIEAEKYDSISYMAVTADGSKVRSNIPPQGQVNAVT 494
Query: 391 WGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDD-PSRKLLEEVKNSYYLV 215
WGVFP E+IQPT+VD SF WKDEAF +W+ W ++YPEDD SR++L ++ Y+L
Sbjct: 495 WGVFPNSEIIQPTVVDVTSFMAWKDEAFALWN-EWMDVYPEDDHQSRQVLNFIRQHYFLC 553
Query: 214 SLVDNNYINGDIFS 173
++VDN+++ GD+FS
Sbjct: 554 TVVDNDFVAGDLFS 567
[35][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 135 bits (340), Expect = 2e-30
Identities = 65/134 (48%), Positives = 96/134 (71%), Gaps = 5/134 (3%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVE--KSKAFPSITYMAVNKSENWVSNT--GESDVNAVT 392
GG+VYQKAY+EFFC + +L+ L+ +++ + SI+YMAV + V + + VNAVT
Sbjct: 414 GGFVYQKAYVEFFCPEGQLEQLIRGIEAEKYDSISYMAVTADGSKVRSNIPPQGQVNAVT 473
Query: 391 WGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDD-PSRKLLEEVKNSYYLV 215
WGVFP E+IQPT+VD SF WKDEAF +W+ W ++YPEDD SR++L ++ Y+L
Sbjct: 474 WGVFPNSEIIQPTVVDVTSFMAWKDEAFALWN-EWMDVYPEDDHQSRQVLNFIRQHYFLC 532
Query: 214 SLVDNNYINGDIFS 173
++VDN+++ GD+FS
Sbjct: 533 TVVDNDFVAGDLFS 546
[36][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 135 bits (340), Expect = 2e-30
Identities = 59/123 (47%), Positives = 85/123 (69%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S++ + L++ K + + Y VN ++N E NAVTWG+
Sbjct: 504 GGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGI 563
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+IQPT+VDP SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV+LVD
Sbjct: 564 FPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYEEESPSRTIIQYIHDNYFLVNLVD 623
Query: 202 NNY 194
N++
Sbjct: 624 NDF 626
[37][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 135 bits (340), Expect = 2e-30
Identities = 59/123 (47%), Positives = 85/123 (69%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S++ + L++ K + + Y VN ++N E NAVTWG+
Sbjct: 504 GGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGI 563
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+IQPT+VDP SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV+LVD
Sbjct: 564 FPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYIHDNYFLVNLVD 623
Query: 202 NNY 194
N++
Sbjct: 624 NDF 626
[38][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 135 bits (339), Expect = 3e-30
Identities = 59/123 (47%), Positives = 84/123 (68%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S + ++ L++ K + + Y VN ++N E NAVTWG+
Sbjct: 498 GGYVFQKAYLEFFTSSETVEALLQVLKKYELRVNYHIVNVKGENITNAPELQPNAVTWGI 557
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+IQPT+VDP SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV+LVD
Sbjct: 558 FPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYHLVNLVD 617
Query: 202 NNY 194
N +
Sbjct: 618 NEF 620
[39][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 134 bits (338), Expect = 4e-30
Identities = 60/123 (48%), Positives = 85/123 (69%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S + + L++ K + + Y VN ++N + NAVTWG+
Sbjct: 506 GGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVQGQNITNAPDLQPNAVTWGI 565
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+IQPT+VDP SF WKDEAF +W WA LY E+ PSR +++ + ++YYLV+LVD
Sbjct: 566 FPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVD 625
Query: 202 NNY 194
N++
Sbjct: 626 NDF 628
[40][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
RepID=UPI0000E814FF
Length = 508
Score = 134 bits (338), Expect = 4e-30
Identities = 60/123 (48%), Positives = 85/123 (69%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S + + L++ K + + Y VN ++N + NAVTWG+
Sbjct: 363 GGYVFQKAYLEFFTSNEIVTALLKVLKKYELRVNYHIVNVKGQNITNAPDLQPNAVTWGI 422
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+IQPT+VDP SF WKDEAF +W WA LY E+ PSR +++ + ++YYLV+LVD
Sbjct: 423 FPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVD 482
Query: 202 NNY 194
N++
Sbjct: 483 NDF 485
[41][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 134 bits (338), Expect = 4e-30
Identities = 57/124 (45%), Positives = 86/124 (69%), Gaps = 1/124 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S++ ++ L++ K + + Y V+ ++N E NAVTWG+
Sbjct: 509 GGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGI 568
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E++QPT+VDP SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV+LVD
Sbjct: 569 FPGREIVQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVD 628
Query: 202 NNYI 191
N ++
Sbjct: 629 NEFL 632
[42][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 134 bits (338), Expect = 4e-30
Identities = 57/124 (45%), Positives = 86/124 (69%), Gaps = 1/124 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S++ ++ L++ K + + Y V+ ++N E NAVTWG+
Sbjct: 544 GGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGI 603
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E++QPT+VDP SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV+LVD
Sbjct: 604 FPGREIVQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVD 663
Query: 202 NNYI 191
N ++
Sbjct: 664 NEFL 667
[43][TOP]
>UniRef100_UPI0000ECA34F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Gallus
gallus RepID=UPI0000ECA34F
Length = 640
Score = 134 bits (338), Expect = 4e-30
Identities = 60/123 (48%), Positives = 85/123 (69%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S + + L++ K + + Y VN ++N + NAVTWG+
Sbjct: 495 GGYVFQKAYLEFFTSNEIVTALLKVLKKYELRVNYHIVNVKGQNITNAPDLQPNAVTWGI 554
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+IQPT+VDP SF WKDEAF +W WA LY E+ PSR +++ + ++YYLV+LVD
Sbjct: 555 FPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVD 614
Query: 202 NNY 194
N++
Sbjct: 615 NDF 617
[44][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 134 bits (337), Expect = 5e-30
Identities = 58/123 (47%), Positives = 86/123 (69%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S++ ++ L++ K + + Y V+ ++N E NAVTWG+
Sbjct: 503 GGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGI 562
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+IQPT+VDP SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV+LVD
Sbjct: 563 FPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVD 622
Query: 202 NNY 194
N++
Sbjct: 623 NDF 625
[45][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 134 bits (337), Expect = 5e-30
Identities = 58/123 (47%), Positives = 85/123 (69%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S++ ++ L++ K + + Y V+ ++N E NAVTWG+
Sbjct: 503 GGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGI 562
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+IQPT+VDP SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV+LVD
Sbjct: 563 FPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVD 622
Query: 202 NNY 194
N +
Sbjct: 623 NEF 625
[46][TOP]
>UniRef100_Q497H7 Mthfr protein (Fragment) n=2 Tax=Mus musculus RepID=Q497H7_MOUSE
Length = 166
Score = 134 bits (337), Expect = 5e-30
Identities = 58/123 (47%), Positives = 85/123 (69%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S++ ++ L++ K + + Y V+ ++N E NAVTWG+
Sbjct: 15 GGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGI 74
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+IQPT+VDP SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV+LVD
Sbjct: 75 FPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVD 134
Query: 202 NNY 194
N +
Sbjct: 135 NEF 137
[47][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 134 bits (337), Expect = 5e-30
Identities = 58/123 (47%), Positives = 85/123 (69%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S++ ++ L++ K + + Y V+ ++N E NAVTWG+
Sbjct: 544 GGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGI 603
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+IQPT+VDP SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV+LVD
Sbjct: 604 FPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVD 663
Query: 202 NNY 194
N +
Sbjct: 664 NEF 666
[48][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 134 bits (337), Expect = 5e-30
Identities = 58/123 (47%), Positives = 85/123 (69%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S++ ++ L++ K + + Y V+ ++N E NAVTWG+
Sbjct: 544 GGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGI 603
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+IQPT+VDP SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV+LVD
Sbjct: 604 FPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVD 663
Query: 202 NNY 194
N +
Sbjct: 664 NEF 666
[49][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 134 bits (337), Expect = 5e-30
Identities = 58/123 (47%), Positives = 85/123 (69%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S++ ++ L++ K + + Y V+ ++N E NAVTWG+
Sbjct: 503 GGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGI 562
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+IQPT+VDP SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV+LVD
Sbjct: 563 FPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVD 622
Query: 202 NNY 194
N +
Sbjct: 623 NEF 625
[50][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 134 bits (337), Expect = 5e-30
Identities = 58/123 (47%), Positives = 85/123 (69%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S++ ++ L++ K + + Y V+ ++N E NAVTWG+
Sbjct: 503 GGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGI 562
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+IQPT+VDP SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV+LVD
Sbjct: 563 FPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVD 622
Query: 202 NNY 194
N +
Sbjct: 623 NEF 625
[51][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 134 bits (336), Expect = 6e-30
Identities = 58/123 (47%), Positives = 85/123 (69%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYVYQKAYLEFF S + + L++ K + P + Y VN ++N + NAVTWG+
Sbjct: 508 GGYVYQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPNAVTWGI 567
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
F +E++QPT+VDP SF WKDEAF +W WA LY ++ PSR +++ + ++Y+LV+LVD
Sbjct: 568 FAGREIVQPTVVDPVSFMSWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLVNLVD 627
Query: 202 NNY 194
N++
Sbjct: 628 NDF 630
[52][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Canis lupus familiaris RepID=UPI00005A03BF
Length = 780
Score = 133 bits (334), Expect = 1e-29
Identities = 58/123 (47%), Positives = 84/123 (68%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S++ + L++ K + + Y V+ ++N E NAVTWG+
Sbjct: 629 GGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGI 688
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+IQPT+VDP SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV+LVD
Sbjct: 689 FPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVD 748
Query: 202 NNY 194
N +
Sbjct: 749 NEF 751
[53][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 133 bits (334), Expect = 1e-29
Identities = 58/123 (47%), Positives = 84/123 (68%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S++ + L++ K + + Y V+ ++N E NAVTWG+
Sbjct: 545 GGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGI 604
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+IQPT+VDP SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV+LVD
Sbjct: 605 FPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVD 664
Query: 202 NNY 194
N +
Sbjct: 665 NEF 667
[54][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S5W8_NEMVE
Length = 619
Score = 133 bits (334), Expect = 1e-29
Identities = 62/127 (48%), Positives = 84/127 (66%), Gaps = 1/127 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKS-ENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF ++ L + K I + VN S E+ +N NAVTWGV
Sbjct: 478 GGYVFQKAYLEFFAREEIALELYHQLKDGTRINFHLVNSSGESDFTNANMYSPNAVTWGV 537
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP E++QPT+VDP +F WKDEAF +W + W LYPE SR +++ + +SYYLV+LVD
Sbjct: 538 FPGSEILQPTVVDPIAFHYWKDEAFGLWKQQWGRLYPEGSRSRDIIDSIYDSYYLVNLVD 597
Query: 202 NNYINGD 182
N+Y+ G+
Sbjct: 598 NDYVGGN 604
[55][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 132 bits (332), Expect = 2e-29
Identities = 58/123 (47%), Positives = 84/123 (68%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S++ ++ L++ K + + Y V+ ++N E NAVTWG+
Sbjct: 544 GGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGI 603
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+IQPT+VDP SF WKDEAF W W LY E+ PSR +++ + ++Y+LV+LVD
Sbjct: 604 FPGREIIQPTVVDPISFMFWKDEAFAPWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVD 663
Query: 202 NNY 194
N +
Sbjct: 664 NEF 666
[56][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 132 bits (331), Expect = 2e-29
Identities = 61/127 (48%), Positives = 82/127 (64%), Gaps = 1/127 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENW-VSNTGESDVNAVTWGV 383
GGY+YQKAYLEFF K +D L+E P + Y ++ + +N AVTWGV
Sbjct: 482 GGYIYQKAYLEFFMHKKNVDFLLEVLNDNPRVNYHIIDSHGCYDKTNADRYSPIAVTWGV 541
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP KE+IQPT+VDP SF WKDEAF +W W +LY + S K+++ + N +YLV+LVD
Sbjct: 542 FPGKEIIQPTVVDPISFNFWKDEAFSLWIEKWQSLYEPESFSAKIIQSIYNDFYLVNLVD 601
Query: 202 NNYINGD 182
N+YI G+
Sbjct: 602 NDYIKGN 608
[57][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 132 bits (331), Expect = 2e-29
Identities = 58/123 (47%), Positives = 83/123 (67%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S + + L++ K + + Y VN ++N + NAVTWG+
Sbjct: 501 GGYVFQKAYLEFFTSSETVAALLKVLKKYELRVNYHIVNVKGENITNAPDMQPNAVTWGI 560
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+IQPT+VDP SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV+LVD
Sbjct: 561 FPGREIIQPTVVDPVSFMSWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYHLVNLVD 620
Query: 202 NNY 194
N +
Sbjct: 621 NEF 623
[58][TOP]
>UniRef100_A8Q9P3 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8Q9P3_MALGO
Length = 515
Score = 130 bits (326), Expect = 9e-29
Identities = 64/121 (52%), Positives = 83/121 (68%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLEFF S +LD L+ + A P ITY AVN + +NT NAVTWG FP
Sbjct: 378 GYVYQKAYLEFFVSPQQLDELIARFDAHPQITYHAVNAQGDMRTNTTSDAPNAVTWGCFP 437
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
E++QPTIV+ SF WKDEA+EI R WA Y + P+R+LLE V ++Y+LV++V N+
Sbjct: 438 HCEILQPTIVESMSFLAWKDEAYEI-GRRWAAFYEPESPTRRLLEHVFDTYFLVNVVHND 496
Query: 196 Y 194
+
Sbjct: 497 F 497
[59][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 128 bits (321), Expect = 3e-28
Identities = 61/124 (49%), Positives = 83/124 (66%), Gaps = 2/124 (1%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTL-VEKSKAFPSITYMAVNKSENWV-SNTGESDVNAVTWG 386
GGY+ QKAYLEFF +K + L K P + Y +NK +N S+ NAVTWG
Sbjct: 477 GGYISQKAYLEFFINKHYAEALKTVLPKYHPRVNYHMINKCGTTDHTNADRSNPNAVTWG 536
Query: 385 VFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLV 206
+F KE+IQPT+VDP SF VWKDEAF +W WA+LY + SR+++ ++ ++YYLV+LV
Sbjct: 537 IFAGKEIIQPTVVDPVSFIVWKDEAFGLWHERWASLYEKGSKSREIINDIADNYYLVNLV 596
Query: 205 DNNY 194
DN+Y
Sbjct: 597 DNDY 600
[60][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 127 bits (318), Expect = 7e-28
Identities = 58/125 (46%), Positives = 82/125 (65%), Gaps = 1/125 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE-SDVNAVTWGV 383
GGY+YQKAY E FCS + + LV K S+ AVN + N + E V A+TWGV
Sbjct: 491 GGYIYQKAYCECFCSPENMRCLVNMVKQNQSMNVYAVNNAGNCIQEGTELGGVTALTWGV 550
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E++QPTI DP F VW +EAF +W+ W+NLY D S L+E ++++YYL +++D
Sbjct: 551 FPNREILQPTIFDPRIFLVWAEEAFSLWTSMWSNLYDYDSDSFDLIETIRDTYYLCAIID 610
Query: 202 NNYIN 188
N+YI+
Sbjct: 611 NDYIS 615
[61][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 127 bits (318), Expect = 7e-28
Identities = 60/124 (48%), Positives = 89/124 (71%), Gaps = 2/124 (1%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS--ITYMAVNKSENWVSNTGESDVNAVTWG 386
GGYV+QKA++EFF ++D+++ L EK + IT A N+ ++ +NT + VNAVTWG
Sbjct: 496 GGYVFQKAFVEFFVTEDEVNRLKEKVEREGKGLITMYAANRKGDFKTNTDKDSVNAVTWG 555
Query: 385 VFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLV 206
VFP +E+ Q TI++ SF WK+EAF+IW+ W+ LYP + PSRKLLE + N ++LVSL+
Sbjct: 556 VFPGQEIAQSTIIEETSFLAWKEEAFDIWA-EWSLLYPRNTPSRKLLEGIANEWWLVSLI 614
Query: 205 DNNY 194
++Y
Sbjct: 615 HHDY 618
[62][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 125 bits (315), Expect = 2e-27
Identities = 62/130 (47%), Positives = 85/130 (65%), Gaps = 1/130 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLE S + + + ++ P +TY AV KS N +N NAVTWGVFP
Sbjct: 452 GYVYQKAYLEMLISPELFPQIKSRIESHPDLTYHAVTKSGNLHTNAQFEGPNAVTWGVFP 511
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
KE++QPTIV+ SF WKDEAF++ WA Y PSR +L+E+ N++YLV++V+N+
Sbjct: 512 GKEIVQPTIVERISFLAWKDEAFQL-GMEWARCYETGTPSRSILDEIMNTWYLVNIVNND 570
Query: 196 YINGD-IFSV 170
+ G+ IF V
Sbjct: 571 FHRGETIFEV 580
[63][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 125 bits (314), Expect = 2e-27
Identities = 65/131 (49%), Positives = 86/131 (65%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLEFF L L++ + +ITY +NK + +NT NAVTWGVFP
Sbjct: 413 GYVYQKAYLEFFVDPALLQLLLKHLERDTNITYHVINKRGDLQTNTHSEGPNAVTWGVFP 472
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
KE+IQPTIV+ SF WKDEA+E+ ++ WA LY D PS+KL+ + +Y LV++V N+
Sbjct: 473 GKEIIQPTIVEAISFMAWKDEAYELGAQ-WARLYEHDSPSQKLILNLMENYALVNVVHND 531
Query: 196 YINGD-IFSVF 167
+ N D IF F
Sbjct: 532 FHNPDAIFEPF 542
[64][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 124 bits (312), Expect = 4e-27
Identities = 59/121 (48%), Positives = 79/121 (65%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLE S + + + + P ITY AV KS N +N NAVTWGVFP
Sbjct: 452 GYVYQKAYLELLVSPELFPEIKRRIEDHPDITYYAVTKSGNLHTNAPSEGPNAVTWGVFP 511
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
KE++QPTIV+ SF WKDEAF++ WA Y D PSR L+EE+ + +YL+++V+N+
Sbjct: 512 GKEIVQPTIVESISFLAWKDEAFQL-GLEWARCYDADTPSRLLIEEIMDKWYLINIVNND 570
Query: 196 Y 194
+
Sbjct: 571 F 571
[65][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 124 bits (312), Expect = 4e-27
Identities = 61/125 (48%), Positives = 82/125 (65%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLE S + + ++ + P +TY AV KS +N NAVTWGVFP
Sbjct: 452 GYVYQKAYLELLVSPEVYPEIKKRIENHPDLTYHAVTKSGMLETNAPSDAPNAVTWGVFP 511
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
KE++QPTIV+ SF WKDEAF++ S WA Y D PSR LLE++ S+YLV++V+N+
Sbjct: 512 GKEIVQPTIVERISFLAWKDEAFQLGS-DWARCYEADTPSRLLLEDIMKSWYLVNIVNND 570
Query: 196 YINGD 182
+ G+
Sbjct: 571 FHQGE 575
[66][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 124 bits (311), Expect = 5e-27
Identities = 63/131 (48%), Positives = 87/131 (66%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLEFF + L+ L+ + +ITY +NK + +NT NAVTWGVFP
Sbjct: 453 GYVYQKAYLEFFVNPTLLNLLLTHIERDSNITYYVINKRGDLRTNTHSDGPNAVTWGVFP 512
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
KE++QPTIV+ SF WKDEAFE+ + WA LY + PS+KL+ E+ ++ +LV++V N+
Sbjct: 513 GKEIVQPTIVEAVSFMAWKDEAFEL-GQQWAKLYEANSPSQKLITELMDTCFLVNVVHND 571
Query: 196 YINGD-IFSVF 167
+ D IF F
Sbjct: 572 FHEPDAIFKPF 582
[67][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 123 bits (309), Expect = 8e-27
Identities = 59/131 (45%), Positives = 88/131 (67%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLE + +D L+ + + P +TY VNK+ + + E NAVTWG+F
Sbjct: 453 GYVYQKAYLELLVPPEHVDELLRRIEKNPDLTYYCVNKTGELKARSDEGP-NAVTWGIFA 511
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+KE+IQPTIV+ SF WKDEA+++ WA +P D PSRKL++ V + +Y++++V+N+
Sbjct: 512 SKEIIQPTIVESVSFMAWKDEAYQL-GEDWAKCHPADSPSRKLIQRVMDEWYILNIVNND 570
Query: 196 Y-INGDIFSVF 167
+ N DIF +F
Sbjct: 571 FHKNDDIFRLF 581
[68][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 120 bits (300), Expect = 9e-26
Identities = 62/132 (46%), Positives = 88/132 (66%), Gaps = 1/132 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLE + + + LV+K + IT+ AVNK+ N +N NAVTWG++P
Sbjct: 452 GYVYQKAYLELLVTPEVAEKLVKKLENQSEITFYAVNKTGNLQTNA-PGGPNAVTWGIYP 510
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
KEVIQPTIV+ SF WK+EAF + S WA YP + SRK L+++ N++YLV++V N+
Sbjct: 511 GKEVIQPTIVEKISFLAWKEEAFRLGS-EWAKCYPAESESRKFLDDIFNNWYLVNIVHND 569
Query: 196 YING-DIFSVFA 164
+ + IF +F+
Sbjct: 570 FHDSTGIFDLFS 581
[69][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 120 bits (300), Expect = 9e-26
Identities = 59/131 (45%), Positives = 88/131 (67%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLE S +D ++ + + P +TY VNK +NT +S NAVTWG+F
Sbjct: 452 GYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKKGELRTNTTDSP-NAVTWGIFA 510
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+KE+IQPTIV+ SF WKDEA+ + WA + PSR+++++V +S+YLV++V+N+
Sbjct: 511 SKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHVASSPSRRIIQQVMDSWYLVNIVNND 569
Query: 196 Y-INGDIFSVF 167
+ DIF++F
Sbjct: 570 FHKTHDIFNIF 580
[70][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 119 bits (299), Expect = 1e-25
Identities = 62/151 (41%), Positives = 93/151 (61%), Gaps = 21/151 (13%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEK--------SKAFPSITYMAVNKSENWVSNTGESDVN 401
G+VYQK YLEFF L L+ S F ++T+ AVN ++N+ E D+N
Sbjct: 450 GFVYQKQYLEFFIPAKFLTKLISNIEELNKSYSSNFNTLTFYAVNAQGELITNSKEDDIN 509
Query: 400 AVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPE----------DDPSRK 251
AVTWG+FP KEV+QPTIV+ SF WKDEAF ++ ++W++L+ + D +R
Sbjct: 510 AVTWGIFPGKEVVQPTIVERCSFLAWKDEAFRVF-KAWSSLFKDQDQDEFEVLRDSKTRA 568
Query: 250 LLEEVKNSYYLVSLVDNNYI---NGDIFSVF 167
+L+++ + Y+LV++VDNNY+ N IF +F
Sbjct: 569 VLDKLHDEYFLVNIVDNNYVQNPNVKIFDLF 599
[71][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 119 bits (299), Expect = 1e-25
Identities = 57/131 (43%), Positives = 88/131 (67%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
G+VYQKAYLE + ++ L+ + + P +TY +NK+ + + E NAVTWG+F
Sbjct: 453 GFVYQKAYLELLVPPEHVEELLRRIEKNPDLTYYCINKTGELRARSDEGP-NAVTWGIFA 511
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+KE+IQPTIV+ SF WKDEA+++ WA +P D PSRKLL+ V + +Y++++V+N+
Sbjct: 512 SKEIIQPTIVESVSFMAWKDEAYQL-GDDWAKCHPADSPSRKLLQRVMDEWYILNIVNND 570
Query: 196 Y-INGDIFSVF 167
+ N DIF +F
Sbjct: 571 FHKNDDIFRLF 581
[72][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 119 bits (298), Expect = 2e-25
Identities = 58/121 (47%), Positives = 75/121 (61%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQK+YLE D ++ + + P +TY AV K SN NAVTWGVFP
Sbjct: 452 GYVYQKSYLELLVHPGVFDKMISRIENHPDLTYYAVTKDGELRSNVTSDGPNAVTWGVFP 511
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
KE++QPTIV+ SF WKDEAF + WA+ Y PSR LLE V N +YLV++V+N+
Sbjct: 512 GKEIVQPTIVESISFLAWKDEAFRL-GVDWAHCYDISSPSRALLEGVMNDWYLVNIVNND 570
Query: 196 Y 194
+
Sbjct: 571 F 571
[73][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 119 bits (298), Expect = 2e-25
Identities = 58/131 (44%), Positives = 88/131 (67%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
G+VYQKAYLE F LD L+ + + P +TY AV K+ +NT +S NA+TWG+F
Sbjct: 452 GFVYQKAYLELFVPPYLLDELIARIEKNPDLTYHAVAKNRELRTNTRDSP-NALTWGIFA 510
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+E++QPTIVD SF WKDEA+ + WA + PSRKL++++ +++YLV++V+N+
Sbjct: 511 GREIVQPTIVDTISFLAWKDEAYRL-GEDWAKCHDASSPSRKLIQDIMDNWYLVNIVNND 569
Query: 196 YING-DIFSVF 167
+ N D+F +F
Sbjct: 570 FHNTYDLFDLF 580
[74][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 119 bits (298), Expect = 2e-25
Identities = 59/130 (45%), Positives = 82/130 (63%), Gaps = 1/130 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQK+YLE D + ++ + + P +T+ AV K SN NAVTWGVFP
Sbjct: 452 GYVYQKSYLELLVHPDVFNDMIGRIENHPDLTFYAVTKDGELRSNAPSDCPNAVTWGVFP 511
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
KE++QPTIV+ SF WKDEAF + WA+ Y + PSR L++EV N +YLV++V+N+
Sbjct: 512 GKEIVQPTIVESISFLAWKDEAFRL-GVDWAHCYDANSPSRALIDEVMNEWYLVNIVNND 570
Query: 196 Y-INGDIFSV 170
+ N IF +
Sbjct: 571 FHQNATIFEL 580
[75][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6H337_AJECH
Length = 524
Score = 119 bits (298), Expect = 2e-25
Identities = 59/131 (45%), Positives = 88/131 (67%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLE S +D ++ + + P +TY VNK +NT +S NAVTWG+F
Sbjct: 343 GYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKIGELRTNTTDSP-NAVTWGIFA 401
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+KE+IQPTIV+ SF WKDEA+ + WA + PSR+++++V +S+YLV++V+N+
Sbjct: 402 SKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHVASSPSRRIIQQVMDSWYLVNIVNND 460
Query: 196 Y-INGDIFSVF 167
+ DIF++F
Sbjct: 461 FHKTHDIFNIF 471
[76][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 119 bits (298), Expect = 2e-25
Identities = 58/131 (44%), Positives = 88/131 (67%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
G+VYQKAYLE F LD L+ + + P +TY AV K+ +NT +S NA+TWG+F
Sbjct: 452 GFVYQKAYLELFVPPYLLDELIARIEKNPDLTYHAVAKNRELRTNTRDSP-NALTWGIFA 510
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+E++QPTIVD SF WKDEA+ + WA + PSRKL++++ +++YLV++V+N+
Sbjct: 511 GREIVQPTIVDTISFLAWKDEAYRL-GEDWAKCHDASSPSRKLIQDIMDNWYLVNIVNND 569
Query: 196 YING-DIFSVF 167
+ N D+F +F
Sbjct: 570 FHNTYDLFDLF 580
[77][TOP]
>UniRef100_B6JY06 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6JY06_SCHJY
Length = 626
Score = 118 bits (296), Expect = 3e-25
Identities = 53/124 (42%), Positives = 80/124 (64%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GG+V+QKA++E F S + L ++ P ITY+A N + +N NAVTWGVF
Sbjct: 494 GGWVFQKAFVEMFMSTMDFEALAQRLHDNPQITYLAGNNKGEFKTNASLDSANAVTWGVF 553
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
P +E+IQ TI+ P SF+ W+DEA+ IW WA LYP PS KL++ ++ +LVS++ +
Sbjct: 554 PGREIIQSTIIAPVSFQAWRDEAYSIWG-EWARLYPAGTPSHKLIQSCIDNCWLVSVIHH 612
Query: 199 NYIN 188
N+++
Sbjct: 613 NFLD 616
[78][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 118 bits (295), Expect = 3e-25
Identities = 59/131 (45%), Positives = 87/131 (66%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLE + + ++ + + P +TY A+NK+ +NT +S NAVTWG+F
Sbjct: 452 GYVYQKAYLELLIPPEVIGEVIRRIEKNPDLTYYAINKNGELKTNTSDSP-NAVTWGIFA 510
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+KEVIQPTIV+ SF WKDEAF + WA + PSR+L++ V + +YLV++V+N+
Sbjct: 511 SKEVIQPTIVETVSFLAWKDEAFRL-GDDWAKCHDARSPSRQLIQRVMDEWYLVNIVNND 569
Query: 196 Y-INGDIFSVF 167
+ DIF++F
Sbjct: 570 FHKTHDIFNLF 580
[79][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 118 bits (295), Expect = 3e-25
Identities = 58/131 (44%), Positives = 88/131 (67%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLE S ++ ++ + + +TY VNK+ +NT +S NAVTWG+F
Sbjct: 452 GYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVNKTGELRTNTSDSP-NAVTWGIFV 510
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+KE+IQPTIV+ SF WKDEA+ + WA +P PSR+L+++V +++YLV++V+N+
Sbjct: 511 SKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHPASSPSRRLIQQVMDTWYLVNIVNND 569
Query: 196 Y-INGDIFSVF 167
+ DIF +F
Sbjct: 570 FHRTHDIFDLF 580
[80][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 118 bits (295), Expect = 3e-25
Identities = 58/131 (44%), Positives = 88/131 (67%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLE S ++ ++ + + +TY VNK+ +NT +S NAVTWG+F
Sbjct: 452 GYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVNKTGELRTNTSDSP-NAVTWGIFV 510
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+KE+IQPTIV+ SF WKDEA+ + WA +P PSR+L+++V +++YLV++V+N+
Sbjct: 511 SKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHPASSPSRRLIQQVMDTWYLVNIVNND 569
Query: 196 Y-INGDIFSVF 167
+ DIF +F
Sbjct: 570 FHRTHDIFDLF 580
[81][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 118 bits (295), Expect = 3e-25
Identities = 58/131 (44%), Positives = 88/131 (67%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLE S +D ++ + + P +TY VNK +NT +S NAVTWG+F
Sbjct: 438 GYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKIGELRTNTTDSP-NAVTWGIFA 496
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+KE+IQPTIV+ SF WKDEA+ + WA + PSR+++++V +++YLV++V+N+
Sbjct: 497 SKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHGASSPSRRIIQQVMDNWYLVNIVNND 555
Query: 196 Y-INGDIFSVF 167
+ DIF++F
Sbjct: 556 FHKTHDIFNIF 566
[82][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
RepID=A8PV87_BRUMA
Length = 656
Score = 117 bits (294), Expect = 5e-25
Identities = 61/124 (49%), Positives = 80/124 (64%), Gaps = 2/124 (1%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSE--NWVSNTGESDVNAVTWG 386
GGY YQKAYLEFF S+ + L ++ + VN +W +NT + AVTWG
Sbjct: 519 GGYCYQKAYLEFFTSQANAEVLWSLLPSYSRLNCHIVNHDATIDW-TNTETTMPIAVTWG 577
Query: 385 VFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLV 206
VFP E+ QPT+VDP SF+VWKDEAF W +W+++Y E SR LLE++ N Y LV+LV
Sbjct: 578 VFPGSEIAQPTVVDPLSFRVWKDEAFSAW-LNWSSIYAEGTSSRCLLEKIYNEYCLVTLV 636
Query: 205 DNNY 194
DN+Y
Sbjct: 637 DNDY 640
[83][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 117 bits (294), Expect = 5e-25
Identities = 59/131 (45%), Positives = 86/131 (65%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLE + + ++ + + P +TY A+NK+ +NT +S NAVTWG+F
Sbjct: 452 GYVYQKAYLELLIPPEVIGEVIRRIEKNPDLTYYAINKNGELKTNTSDSP-NAVTWGIFA 510
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+KEVIQPTIV+ SF WKDEAF + WA + PSR+L++ V + +YLV++V+N+
Sbjct: 511 SKEVIQPTIVETVSFLAWKDEAFRL-GDDWAKCHDARSPSRQLIQRVMDEWYLVNIVNND 569
Query: 196 Y-INGDIFSVF 167
+ DIF +F
Sbjct: 570 FHKTHDIFDLF 580
[84][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 117 bits (294), Expect = 5e-25
Identities = 57/131 (43%), Positives = 88/131 (67%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
G+VYQKAYLE F LD L+ + + P +TY AV K+ +NT +S NA+TWG+F
Sbjct: 452 GFVYQKAYLELFVPPYLLDELIARIEKNPDLTYHAVAKNRELRTNTRDSP-NALTWGIFA 510
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+E++QPTIV+ SF WKDEA+ + WA + PSRKL++++ +++YLV++V+N+
Sbjct: 511 GREIVQPTIVETISFLAWKDEAYRL-GEDWAKCHDASSPSRKLIQDIMDNWYLVNIVNND 569
Query: 196 YING-DIFSVF 167
+ N D+F +F
Sbjct: 570 FHNTYDLFDLF 580
[85][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 117 bits (293), Expect = 6e-25
Identities = 58/131 (44%), Positives = 88/131 (67%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLE S ++ ++ + + +TY VNK+ +NT +S NAVTWG+F
Sbjct: 452 GYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVNKTGELRTNTTDSP-NAVTWGIFV 510
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+KE+IQPTIV+ SF WKDEA+ + WA +P PSR+L+++V +++YLV++V+N+
Sbjct: 511 SKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHPASSPSRRLIQQVMDTWYLVNIVNND 569
Query: 196 Y-INGDIFSVF 167
+ DIF +F
Sbjct: 570 FHRTHDIFDLF 580
[86][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 117 bits (292), Expect = 8e-25
Identities = 51/109 (46%), Positives = 72/109 (66%), Gaps = 1/109 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYVYQKAYLEFF S + + L++ K + P + Y VN ++N + NAVTWG+
Sbjct: 508 GGYVYQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPNAVTWGI 567
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
F +E++QPT+VDP SF WKDEAF +W WA LY ++ PSR +++ +
Sbjct: 568 FAGREIVQPTVVDPVSFMSWKDEAFALWIEQWAKLYEDESPSRMIIQYI 616
[87][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 117 bits (292), Expect = 8e-25
Identities = 60/131 (45%), Positives = 81/131 (61%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYV+QK Y+EFF L+ L E K S++Y NK+ + +N+ NAVTWGVFP
Sbjct: 455 GYVFQKPYVEFFVHPSLLNELKETVKKLNSVSYFVTNKNGDLDTNSQYEIPNAVTWGVFP 514
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+E+IQPTIV+ SF WKDEA+ + WAN Y D SRKLL + ++L +VDN+
Sbjct: 515 NREIIQPTIVESTSFLAWKDEAYSL-GMEWANAYSPDSISRKLLVSMMKEWFLCVIVDND 573
Query: 196 YING-DIFSVF 167
+ NG +F VF
Sbjct: 574 FQNGQSLFDVF 584
[88][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 116 bits (291), Expect = 1e-24
Identities = 59/147 (40%), Positives = 90/147 (61%), Gaps = 1/147 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLE S + + ++ + + P TY AVNK + +N NAVTWGVFP
Sbjct: 452 GYVYQKAYLEVLVSPEYIAEIITRIERDPEFTYYAVNKDGDLKTNAPNEGPNAVTWGVFP 511
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
KE++QPTIV+ SF WKDE + + + WAN + PSR ++++V +++YL+++V N+
Sbjct: 512 GKEIVQPTIVETVSFLAWKDEFYRL-GQQWANCHGGASPSRFVIQDVVDTWYLLNIVHND 570
Query: 196 Y-INGDIFSVFA*SPRKPPAKRKHSIS 119
+ IF +F K K+ HS++
Sbjct: 571 FHATRGIFPIFDGLQVKDIDKKLHSVN 597
[89][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 116 bits (290), Expect = 1e-24
Identities = 54/123 (43%), Positives = 77/123 (62%), Gaps = 1/123 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVS-NTGESDVNAVTWGV 383
GG VYQKAY E F S K + L + PS+ AVN + + E V A+TWGV
Sbjct: 452 GGRVYQKAYFECFVSPSKANRLTQMVTDHPSLNMYAVNNAGQELRVGVEEGGVTALTWGV 511
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E++QPTI DP +F +W +EAF +W W NLY S L++E++++YYLV+L+D
Sbjct: 512 FPNREILQPTIFDPDTFLIWAEEAFSLWGSMWLNLYEYGSESYDLVQEIRDTYYLVALID 571
Query: 202 NNY 194
N++
Sbjct: 572 NDF 574
[90][TOP]
>UniRef100_Q8MQE7 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis elegans
RepID=Q8MQE7_CAEEL
Length = 642
Score = 115 bits (289), Expect = 2e-24
Identities = 54/125 (43%), Positives = 83/125 (66%), Gaps = 3/125 (2%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEK-SKAFP-SITYMAVNKSENW-VSNTGESDVNAVTW 389
GGY YQKAYLE F + + D L++ + FP + Y A+NK + +N+ E+ AVTW
Sbjct: 499 GGYCYQKAYLECFMTAELSDKLIQIIEREFPVRVNYHAINKDSTFDKTNSEETTPIAVTW 558
Query: 388 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSL 209
GVFP E+ QPT+VDP SF+ W+DEA+++W W + YP++ S +++ V + + LV+L
Sbjct: 559 GVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQWGDFYPKESKSYGVIKAVHDEFRLVTL 618
Query: 208 VDNNY 194
VDN++
Sbjct: 619 VDNDF 623
[91][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 115 bits (289), Expect = 2e-24
Identities = 52/121 (42%), Positives = 80/121 (66%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLE F S + + ++ + + P TY AVNK + +N NAVTWGVFP
Sbjct: 452 GYVYQKAYLEVFVSPEYISEIITRLERDPEFTYYAVNKDGDLKTNAPNEGPNAVTWGVFP 511
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
KE++QPTIV+ SF WKDE + + + WAN + PSR +++++ +++YL+++V N+
Sbjct: 512 GKEIVQPTIVETVSFLAWKDEFYRL-GQQWANCHAGVSPSRYVIQDIVDTWYLLNIVHND 570
Query: 196 Y 194
+
Sbjct: 571 F 571
[92][TOP]
>UniRef100_Q17693 Probable methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis
elegans RepID=MTHR_CAEEL
Length = 663
Score = 115 bits (289), Expect = 2e-24
Identities = 54/125 (43%), Positives = 83/125 (66%), Gaps = 3/125 (2%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEK-SKAFP-SITYMAVNKSENW-VSNTGESDVNAVTW 389
GGY YQKAYLE F + + D L++ + FP + Y A+NK + +N+ E+ AVTW
Sbjct: 520 GGYCYQKAYLECFMTAELSDKLIQIIEREFPVRVNYHAINKDSTFDKTNSEETTPIAVTW 579
Query: 388 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSL 209
GVFP E+ QPT+VDP SF+ W+DEA+++W W + YP++ S +++ V + + LV+L
Sbjct: 580 GVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQWGDFYPKESKSYGVIKAVHDEFRLVTL 639
Query: 208 VDNNY 194
VDN++
Sbjct: 640 VDNDF 644
[93][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 115 bits (287), Expect = 3e-24
Identities = 55/121 (45%), Positives = 77/121 (63%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLE + L E+ P +TY AV KS N +N NAVTWGVFP
Sbjct: 447 GYVYQKAYLELLVHPAIFEQLKERIHDHPDLTYYAVTKSGNLHTNATYEGPNAVTWGVFP 506
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
KE++QPT+V+ SF WKDEAF++ WA + ++ PSR L++ + +YLV++V+N+
Sbjct: 507 GKEIVQPTVVENISFLAWKDEAFQL-GMEWARCHDQNTPSRILIQSMMQEWYLVNIVNND 565
Query: 196 Y 194
+
Sbjct: 566 F 566
[94][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 115 bits (287), Expect = 3e-24
Identities = 59/131 (45%), Positives = 86/131 (65%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
G+VYQKAYLE F LD L+ + + +TY AV K +NT +S NA+TWG+F
Sbjct: 452 GFVYQKAYLELFVPPYLLDELIARIEKNDDLTYHAVAKEGELRTNTRDSP-NALTWGIFA 510
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+E++QPTIV+ SF WKDEA+ + WA + PSRKL++EV +S+YLV++V+N+
Sbjct: 511 GREIVQPTIVETISFLAWKDEAYRL-GEDWAKCHEAASPSRKLIQEVVDSWYLVNIVNND 569
Query: 196 YING-DIFSVF 167
+ N D+F +F
Sbjct: 570 FHNTYDLFELF 580
[95][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 114 bits (286), Expect = 4e-24
Identities = 56/121 (46%), Positives = 77/121 (63%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLE + D + LV + + P +TY AV K+ + +N NAVTWGVFP
Sbjct: 452 GYVYQKAYLELLVAPDMMPELVRRIQHDPDLTYYAVKKTGDLQTNAQSDGPNAVTWGVFP 511
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
KE++QPTIV+ SF WKDEAF + WA+ + PSR L+E + +S+YLV++ N
Sbjct: 512 GKEIVQPTIVETISFLAWKDEAFRL-GTDWAHCHSALSPSRGLIESIMDSWYLVNIGRAN 570
Query: 196 Y 194
+
Sbjct: 571 F 571
[96][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 114 bits (285), Expect = 5e-24
Identities = 52/125 (41%), Positives = 86/125 (68%), Gaps = 3/125 (2%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCS---KDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTW 389
GG+V+QK+++E F S KD+L ++ A ITY A N ++ SN G+ + N VTW
Sbjct: 549 GGFVFQKSFVELFVSSSDKDRLVARIDALGASAPITYFAGNAKGDFQSNLGDEEANTVTW 608
Query: 388 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSL 209
VFP KE++Q TI++ SF+ W++EAFEIW+ W+ L+P+ SR+L++E++ + +LV++
Sbjct: 609 AVFPGKEIVQSTIIERQSFEAWREEAFEIWA-EWSLLFPKKSASRQLIDEIREARWLVTV 667
Query: 208 VDNNY 194
V ++Y
Sbjct: 668 VHHDY 672
[97][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 114 bits (285), Expect = 5e-24
Identities = 58/131 (44%), Positives = 86/131 (65%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLE S +D ++ + + +TY VNK +NT +S NAVTWG+F
Sbjct: 452 GYVYQKAYLELLISPTMIDDVISRIEQNSDLTYYCVNKKGELKTNTTDSP-NAVTWGIFA 510
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+KE+IQPTIV+ SF WKDEA+ + WA + SR+L+E+V +++YLV++V+N+
Sbjct: 511 SKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHAPSSLSRRLIEQVMDTWYLVNIVNND 569
Query: 196 Y-INGDIFSVF 167
+ DIF++F
Sbjct: 570 FHKTHDIFNLF 580
[98][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 114 bits (285), Expect = 5e-24
Identities = 58/131 (44%), Positives = 86/131 (65%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLE S +D ++ + + +TY VNK +NT +S NAVTWG+F
Sbjct: 452 GYVYQKAYLELLISPTMIDDVISRIEQNSDLTYYCVNKKGELKTNTTDSP-NAVTWGIFA 510
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+KE+IQPTIV+ SF WKDEA+ + WA + SR+L+E+V +++YLV++V+N+
Sbjct: 511 SKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHAPSSLSRRLIEQVMDTWYLVNIVNND 569
Query: 196 Y-INGDIFSVF 167
+ DIF++F
Sbjct: 570 FHKTHDIFNLF 580
[99][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 114 bits (285), Expect = 5e-24
Identities = 58/131 (44%), Positives = 85/131 (64%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLE + +D ++ + + +TY A NK+ +NT +S NAVTWG+F
Sbjct: 452 GYVYQKAYLELLIPPEIIDEVITRIQKNADLTYYATNKNGELKTNTSDSP-NAVTWGIFA 510
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+KEVIQPTIV+ SF WKDEA+ + WA + PSR+L++ V + +YLV++V+N+
Sbjct: 511 SKEVIQPTIVETVSFLAWKDEAYRL-GDDWAKCHDARSPSRQLIQRVMDEWYLVNIVNND 569
Query: 196 Y-INGDIFSVF 167
+ DIF +F
Sbjct: 570 FHKTHDIFDLF 580
[100][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 114 bits (284), Expect = 7e-24
Identities = 57/131 (43%), Positives = 86/131 (65%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
G+VYQKAYLE +D L+ + +A +TY AV K +NT +S NA+TWG+F
Sbjct: 452 GFVYQKAYLELLVPPYVIDELIARIEANEDLTYHAVTKKGELRTNTRDSP-NALTWGIFA 510
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+EV+QPTIV+ SF WKDEA+++ WA + P+RKLL+ + +S+YLV++V+N+
Sbjct: 511 GREVVQPTIVETVSFLAWKDEAYQL-GEDWAKCHEASSPTRKLLQGIMDSWYLVNIVNND 569
Query: 196 YING-DIFSVF 167
+ N D+F +F
Sbjct: 570 FHNTYDLFELF 580
[101][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 114 bits (284), Expect = 7e-24
Identities = 55/131 (41%), Positives = 85/131 (64%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLE S +D ++ + + P +TY +NK+ +N+ ++ NAVTWG+F
Sbjct: 452 GYVYQKAYLELLISPTLIDEVIRRIETNPDLTYHCINKNGELRTNSSDTP-NAVTWGIFA 510
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+KEVIQPTIV+ SF WKDEA+ + WA + PSRK+++ +++YL ++V+N+
Sbjct: 511 SKEVIQPTIVETVSFLAWKDEAYRL-GDDWAKCHDASSPSRKIIQNTMDTWYLFNIVNND 569
Query: 196 Y-INGDIFSVF 167
+ DIF +F
Sbjct: 570 FHKTHDIFDLF 580
[102][TOP]
>UniRef100_UPI0000123E6B Hypothetical protein CBG12960 n=1 Tax=Caenorhabditis briggsae AF16
RepID=UPI0000123E6B
Length = 662
Score = 112 bits (279), Expect = 2e-23
Identities = 50/125 (40%), Positives = 85/125 (68%), Gaps = 3/125 (2%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEK-SKAFP-SITYMAVNKSENW-VSNTGESDVNAVTW 389
GGY YQKAYLE F + + + L++ + +P + Y A++K ++ +N+ E+ AVTW
Sbjct: 521 GGYCYQKAYLECFMTAELSEKLIDIIEREYPVRVNYHAIDKDSSFDKTNSEETTPIAVTW 580
Query: 388 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSL 209
GVFP E+ QPT+VDP SF+ W+DEA+++W W + YP++ S +++ + +++ LV+L
Sbjct: 581 GVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQWGDFYPKESKSYGVIKSIHDTFRLVTL 640
Query: 208 VDNNY 194
VDN++
Sbjct: 641 VDNDF 645
[103][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 112 bits (279), Expect = 2e-23
Identities = 56/131 (42%), Positives = 87/131 (66%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
G+VYQKAYLE LD L+ + + +TY AV+K+ +NT +S NA+TWG+F
Sbjct: 452 GFVYQKAYLELLVPPYLLDELIARIEKNEDLTYHAVSKTGELRTNTRDSP-NALTWGIFA 510
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+EV+QPTIV+ SF WKDEA+ + WA + PSRKL+++V +++YLV++V+N+
Sbjct: 511 GREVVQPTIVETISFLAWKDEAYRL-GEDWAKCHEAGSPSRKLIQDVMDNWYLVNIVNND 569
Query: 196 YING-DIFSVF 167
+ N ++F +F
Sbjct: 570 FHNSFNLFELF 580
[104][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 111 bits (278), Expect = 3e-23
Identities = 57/131 (43%), Positives = 86/131 (65%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
G+VYQKAYLE LD L+ + + +TY AV+K+ +NT +S NA+TWG+F
Sbjct: 452 GFVYQKAYLELLIPPYLLDELIARIEGNEDLTYHAVSKNGELRTNTHDSP-NALTWGIFA 510
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+EV+QPTIV+ SF WKDEA+ + WA + PSRKL++ + +S+YLV++V+N+
Sbjct: 511 GREVVQPTIVETISFLAWKDEAYRL-GEDWAKCHAATSPSRKLIQGLVDSWYLVNIVNND 569
Query: 196 YING-DIFSVF 167
+ N D+F +F
Sbjct: 570 FHNTYDLFELF 580
[105][TOP]
>UniRef100_Q6FNS2 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FNS2_CANGA
Length = 645
Score = 110 bits (275), Expect = 7e-23
Identities = 54/128 (42%), Positives = 79/128 (61%), Gaps = 3/128 (2%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAF---PSITYMAVNKSENWVSNTGESDVNAVTWG 386
G+VYQKA++E F + + T+++ + +Y A + ++ +N N VTWG
Sbjct: 511 GHVYQKAFIEMFVHRQQWKTILKPKLDYYGRRKFSYYAGDSKGSFETNLDPHSSNVVTWG 570
Query: 385 VFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLV 206
VFP +VIQ TI++ SFK W+DEAF IWS WA L+P + PS LL EV + YYLVS+V
Sbjct: 571 VFPNSQVIQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPSNTLLREVHSDYYLVSIV 629
Query: 205 DNNYINGD 182
+++I D
Sbjct: 630 HHDFIETD 637
[106][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 110 bits (275), Expect = 7e-23
Identities = 55/141 (39%), Positives = 86/141 (60%), Gaps = 16/141 (11%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPS---------ITYMAVNKSENWVSNTGESDV 404
GYVYQK YLEFFC KD + L++ + I+Y AVNK+ N +SN + D+
Sbjct: 457 GYVYQKQYLEFFCHKDVVARLLDHIDQYNKNQGDSTSAVISYYAVNKNGNLISNCQDDDI 516
Query: 403 NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSR-------KLL 245
NAVTWGVFP +E++QPTIV+ SF WKDE + ++S W+ + D + +L+
Sbjct: 517 NAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYTLFS-EWSKISGMFDAEKDKIQHFNELM 575
Query: 244 EEVKNSYYLVSLVDNNYINGD 182
++ ++ L +LV+N+++ G+
Sbjct: 576 SQITENFVLCNLVNNDFLQGN 596
[107][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 110 bits (274), Expect = 9e-23
Identities = 58/126 (46%), Positives = 80/126 (63%), Gaps = 3/126 (2%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSN-TGESDVNAVTWGVF 380
GYVYQK YLEF K KL L + PS+TY AV+ ++ SN ++ NAVTWG+F
Sbjct: 462 GYVYQKQYLEFLLPKSKLSQLRDFVNDMPSLTYFAVDSADELHSNHPDDTAANAVTWGIF 521
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRK--LLEEVKNSYYLVSLV 206
P +EV+QPTIV+ SF WK+E F+I W + E++ S LLE V + Y LV++V
Sbjct: 522 PGREVLQPTIVEKVSFLAWKEEFFDILD-EWKRIMGENNHSESVALLESVISDYLLVNIV 580
Query: 205 DNNYIN 188
DN+Y++
Sbjct: 581 DNDYVS 586
[108][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NEV2_COPC7
Length = 617
Score = 110 bits (274), Expect = 9e-23
Identities = 55/132 (41%), Positives = 81/132 (61%), Gaps = 2/132 (1%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPS--ITYMAVNKSENWVSNTGESDVNAVTWGV 383
GYV+QK ++EFFC ++ + ++ K + + Y N + SN E NAVTWGV
Sbjct: 478 GYVFQKGFVEFFCDFHDVEAIEQRIKQRGAGWVHYFMANNNGECRSNVPEDGRNAVTWGV 537
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E+ Q TI++ SF WKDEA++IW+ SWA+LY D R+LL++V N +LVS+V
Sbjct: 538 FPGQEIQQTTIIEKESFLTWKDEAYDIWN-SWASLYHPDSAERQLLQKVANERWLVSIVH 596
Query: 202 NNYINGDIFSVF 167
+ Y N + F
Sbjct: 597 HEYKNPNALWTF 608
[109][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR2_SCHPO
Length = 641
Score = 110 bits (274), Expect = 9e-23
Identities = 50/124 (40%), Positives = 79/124 (63%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 380
GG V+QKA++E F + L + K P +TY A N +++N + +AVTWGV+
Sbjct: 507 GGRVFQKAFVECFVNGKDLKDFITKWHDNPQVTYYAGNNKSEFLTNAPKDGASAVTWGVY 566
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
P +E+IQ TI+ SFK W E+F++W WANLY ++ PSRKLLE N +LV+++ +
Sbjct: 567 PGREIIQSTIIAEVSFKAWLSESFQVWG-EWANLYSKNTPSRKLLENCINDRWLVTVIHH 625
Query: 199 NYIN 188
++++
Sbjct: 626 DFMD 629
[110][TOP]
>UniRef100_A8XGR9 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis briggsae
RepID=A8XGR9_CAEBR
Length = 724
Score = 109 bits (273), Expect = 1e-22
Identities = 50/135 (37%), Positives = 86/135 (63%), Gaps = 13/135 (9%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEK-SKAFP-SITYMAVNKSENWV-----------SNT 419
GGY YQKAYLE F + + + L++ + +P + Y A++K +++ +N+
Sbjct: 571 GGYCYQKAYLECFMTAELSEKLIDIIEREYPVRVNYHAIDKDVSYILNSHDSMQIFRTNS 630
Query: 418 GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEE 239
E+ AVTWGVFP E+ QPT+VDP SF+ W+DEA+++W W + YP++ S +++
Sbjct: 631 EETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQWGDFYPKESKSYGVIKS 690
Query: 238 VKNSYYLVSLVDNNY 194
+ +++ LV+LVDN++
Sbjct: 691 IHDTFRLVTLVDNDF 705
[111][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 108 bits (270), Expect = 3e-22
Identities = 54/131 (41%), Positives = 86/131 (65%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQKAYLE +D L+ + + +TY AV+K+ +NT +S NA+TWG+F
Sbjct: 452 GYVYQKAYLELLVPPYLIDELIARIEKNGDLTYHAVSKTGELRTNTRDSP-NALTWGIFA 510
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+E++QPTIV+ SF WKDEA+ + WA + PSRKL++ V ++++LV++V+N+
Sbjct: 511 GREIVQPTIVETVSFLAWKDEAYRL-GDDWAKCHDTSSPSRKLIQGVMDNWHLVNIVNND 569
Query: 196 YIN-GDIFSVF 167
+ N ++F +F
Sbjct: 570 FHNTSNLFDLF 580
[112][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 108 bits (269), Expect = 4e-22
Identities = 53/131 (40%), Positives = 82/131 (62%), Gaps = 1/131 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
G+VYQKAYLE + +D L+ + + +TY A NK +NT +S NA+TWG+F
Sbjct: 452 GFVYQKAYLELLVPSNLIDELITRIEKNDDLTYHATNKKGELKTNTRDSP-NALTWGIFA 510
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
+E+IQPTIV+ SF WKDEA+ + W+ + PSR+L++ V +YLV++VDN+
Sbjct: 511 GREIIQPTIVETVSFLAWKDEAY-LLGEHWSKCHDAASPSRQLIQHVMEDWYLVNIVDND 569
Query: 196 YINGD-IFSVF 167
+ + +F +F
Sbjct: 570 FHRSNAVFELF 580
[113][TOP]
>UniRef100_C4Y9Q4 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y9Q4_CLAL4
Length = 601
Score = 107 bits (268), Expect = 5e-22
Identities = 54/127 (42%), Positives = 79/127 (62%), Gaps = 5/127 (3%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSK---DKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE--SDVNAVT 392
G ++QK+++EFF K ++L L++K + +ITY N +N S A+T
Sbjct: 465 GRIFQKSFVEFFVPKTEWERLLRLMDKDISDKTITYFCGNSKGEITTNMPHKSSQRTAIT 524
Query: 391 WGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP+KEV+QPT++D SF+ W +EAF +W WA Y D PS +LL + + YYLVS
Sbjct: 525 WGVFPSKEVLQPTVIDRQSFQAWNEEAFGLW-LDWARCYAPDSPSYRLLAGIHSDYYLVS 583
Query: 211 LVDNNYI 191
+V NNY+
Sbjct: 584 IVHNNYL 590
[114][TOP]
>UniRef100_UPI000151BABB hypothetical protein PGUG_04648 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151BABB
Length = 355
Score = 107 bits (267), Expect = 6e-22
Identities = 58/152 (38%), Positives = 88/152 (57%), Gaps = 22/152 (14%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPS--------ITYMAVNKSENWVSNTGESDVN 401
GYV+QK YLEFFC +D L+E + F +TY A +K+ +NT E D+N
Sbjct: 197 GYVFQKQYLEFFCHRDIFPKLLESIEKFNEKGGESCSFLTYYAADKNGELNTNTKEDDIN 256
Query: 400 AVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLY----PEDDPSRK------ 251
AVTWGVFP +E++QPTIV+ SF WKDE + + + W ++Y D+ +K
Sbjct: 257 AVTWGVFPGEEILQPTIVEKTSFFAWKDEVYRLLA-EWGSVYDSHITSDETLKKSQVKEF 315
Query: 250 --LLEEVKNSYYLVSLVDNNYINGD--IFSVF 167
L E + + L ++V+NN+++ D +FS+F
Sbjct: 316 THTLNEFADQFILCNIVNNNFVDDDLVLFSIF 347
[115][TOP]
>UniRef100_A5DMZ7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DMZ7_PICGU
Length = 355
Score = 107 bits (267), Expect = 6e-22
Identities = 58/152 (38%), Positives = 88/152 (57%), Gaps = 22/152 (14%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPS--------ITYMAVNKSENWVSNTGESDVN 401
GYV+QK YLEFFC +D L+E + F +TY A +K+ +NT E D+N
Sbjct: 197 GYVFQKQYLEFFCHRDIFPKLLESIEKFNEKGGESCSFLTYYAADKNGELNTNTKEDDIN 256
Query: 400 AVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLY----PEDDPSRK------ 251
AVTWGVFP +E++QPTIV+ SF WKDE + + + W ++Y D+ +K
Sbjct: 257 AVTWGVFPGEEILQPTIVEKTSFFAWKDEVYRLLA-EWGSVYDSHITSDETLKKSQVKEF 315
Query: 250 --LLEEVKNSYYLVSLVDNNYINGD--IFSVF 167
L E + + L ++V+NN+++ D +FS+F
Sbjct: 316 THTLNEFADQFILCNIVNNNFVDDDSVLFSIF 347
[116][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 107 bits (266), Expect = 8e-22
Identities = 54/142 (38%), Positives = 89/142 (62%), Gaps = 17/142 (11%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAF---------PSITYMAVNKSENWVSNTGESDV 404
GYVYQK YLEFFC KD + L+++ + F I+Y AV+K N +N + D+
Sbjct: 457 GYVYQKQYLEFFCHKDVVSKLLDQVEEFNIKGAESSSAFISYYAVDKDGNLSTNCKDDDI 516
Query: 403 NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI---WSRSWANLYPEDDPSR-----KL 248
NAVTWGVFP +E++QPTIV+ SF WKDE + + W++ ++ E D ++ +L
Sbjct: 517 NAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFTEWAKIASSNLVEADQTQVNEFVRL 576
Query: 247 LEEVKNSYYLVSLVDNNYINGD 182
+++ + + L +LV+N++++G+
Sbjct: 577 MKKFGDEFVLCNLVNNDFVDGN 598
[117][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 107 bits (266), Expect = 8e-22
Identities = 56/126 (44%), Positives = 76/126 (60%), Gaps = 4/126 (3%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSK--AFPSITYMAVNKSENWV--SNTGESDVNAVT 392
GGYV+QK ++EFFC + +D + + + + Y A N + SN E NAVT
Sbjct: 462 GGYVFQKGFVEFFCEEKDMDVIERRVERNGHGWVHYFAGNYKADGECRSNVPEGGRNAVT 521
Query: 391 WGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP +E+ Q TI++ SF WKDEAF IWS WA+ Y RKLLE V+N +LVS
Sbjct: 522 WGVFPGQEIAQTTIIEKESFLTWKDEAFSIWS-EWASFYRPGSEERKLLEGVRNERWLVS 580
Query: 211 LVDNNY 194
+V ++Y
Sbjct: 581 IVHHDY 586
[118][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 106 bits (265), Expect = 1e-21
Identities = 57/145 (39%), Positives = 87/145 (60%), Gaps = 20/145 (13%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLV-----------EKSKAFPSITYMAVNKSENWVSNTGES 410
GYVYQK YLEFFC KD + L+ E S AF I+Y AV+K N +N +
Sbjct: 457 GYVYQKQYLEFFCHKDVVSKLLDHVEEFNVKGAESSSAF--ISYYAVDKDGNLSTNCKDD 514
Query: 409 DVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED---------DPS 257
D+NAVTWGVFP +E++QPTIV+ SF WKDE + +++ WA + + D
Sbjct: 515 DINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFT-EWAKIASSNLVEANQTQVDEF 573
Query: 256 RKLLEEVKNSYYLVSLVDNNYINGD 182
+L+++ + + L +LV+N++++G+
Sbjct: 574 VQLMKKFGDEFVLCNLVNNDFVDGN 598
[119][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 104 bits (260), Expect = 4e-21
Identities = 54/127 (42%), Positives = 80/127 (62%), Gaps = 2/127 (1%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE-SDVNAVTWGVF 380
GYVYQK YLEF K KL L++ K +TY A++ + +SN + S NAVTWG+F
Sbjct: 464 GYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIF 523
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDP-SRKLLEEVKNSYYLVSLVD 203
P +E++QPTIV+ SF WK+E + I + N+ D P S + ++ + + Y LV++VD
Sbjct: 524 PGREILQPTIVEKISFLAWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYCLVNIVD 583
Query: 202 NNYINGD 182
N+YI+ D
Sbjct: 584 NDYISPD 590
[120][TOP]
>UniRef100_C5DIA7 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5DIA7_LACTC
Length = 660
Score = 104 bits (260), Expect = 4e-21
Identities = 53/129 (41%), Positives = 80/129 (62%), Gaps = 3/129 (2%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP---SITYMAVNKSENWVSNTGESDVNAVTW 389
GGYVYQK+++E F K + + + K K P ++Y + +E + +N S + VTW
Sbjct: 526 GGYVYQKSFVEMFVHKQQWELEI-KPKLEPLGSKVSYYVGDSAETFYTNLDSSCSSVVTW 584
Query: 388 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSL 209
GVFP EV+Q TIV+ SFK W+DEAF IW W+ L+P + S LL+++ YYLVS+
Sbjct: 585 GVFPNSEVLQTTIVEEESFKAWRDEAFSIW-LEWSKLFPRNSRSNTLLKQMHRDYYLVSI 643
Query: 208 VDNNYINGD 182
V +++ + D
Sbjct: 644 VHHDFSDCD 652
[121][TOP]
>UniRef100_B5VIK4 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VIK4_YEAS6
Length = 411
Score = 104 bits (260), Expect = 4e-21
Identities = 54/127 (42%), Positives = 80/127 (62%), Gaps = 2/127 (1%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE-SDVNAVTWGVF 380
GYVYQK YLEF K KL L++ K +TY A++ + +SN + S NAVTWG+F
Sbjct: 275 GYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIF 334
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDP-SRKLLEEVKNSYYLVSLVD 203
P +E++QPTIV+ SF WK+E + I + N+ D P S + ++ + + Y LV++VD
Sbjct: 335 PGREILQPTIVEKISFLAWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYCLVNIVD 394
Query: 202 NNYINGD 182
N+YI+ D
Sbjct: 395 NDYISPD 401
[122][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 104 bits (260), Expect = 4e-21
Identities = 54/127 (42%), Positives = 80/127 (62%), Gaps = 2/127 (1%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE-SDVNAVTWGVF 380
GYVYQK YLEF K KL L++ K +TY A++ + +SN + S NAVTWG+F
Sbjct: 464 GYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIF 523
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDP-SRKLLEEVKNSYYLVSLVD 203
P +E++QPTIV+ SF WK+E + I + N+ D P S + ++ + + Y LV++VD
Sbjct: 524 PGREILQPTIVEKISFLAWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYCLVNIVD 583
Query: 202 NNYINGD 182
N+YI+ D
Sbjct: 584 NDYISPD 590
[123][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 104 bits (260), Expect = 4e-21
Identities = 54/127 (42%), Positives = 80/127 (62%), Gaps = 2/127 (1%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE-SDVNAVTWGVF 380
GYVYQK YLEF K KL L++ K +TY A++ + +SN + S NAVTWG+F
Sbjct: 464 GYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIF 523
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDP-SRKLLEEVKNSYYLVSLVD 203
P +E++QPTIV+ SF WK+E + I + N+ D P S + ++ + + Y LV++VD
Sbjct: 524 PGREILQPTIVEKISFLAWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYCLVNIVD 583
Query: 202 NNYINGD 182
N+YI+ D
Sbjct: 584 NDYISPD 590
[124][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 104 bits (259), Expect = 5e-21
Identities = 58/141 (41%), Positives = 85/141 (60%), Gaps = 18/141 (12%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVE------KSKAFPS---ITYMAVNKSENWVSNTGESDV 404
GYVYQK YLEFFC KD L L+ KS+ S I+Y AV+K+ N +N + D+
Sbjct: 457 GYVYQKQYLEFFCPKDLLPKLLHTIDSYNKSEGDASSSIISYYAVDKNGNLSTNCKDDDI 516
Query: 403 NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED--DPSR-------K 251
NAVTWGVFP +E++QPTIV+ SF WKDE + +++ W N+ + D +
Sbjct: 517 NAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFT-EWTNILQSNLVDADKDKISGFVD 575
Query: 250 LLEEVKNSYYLVSLVDNNYIN 188
L+ N++ L +LV+N++I+
Sbjct: 576 LITNFSNNFVLCNLVNNDFID 596
[125][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 103 bits (258), Expect = 7e-21
Identities = 56/145 (38%), Positives = 84/145 (57%), Gaps = 20/145 (13%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPS---------ITYMAVNKSENWVSNTGESDV 404
GYVYQK YLEFFC KD + L++ + + I+Y AV+ N +N + D+
Sbjct: 458 GYVYQKQYLEFFCHKDIIVKLLQTIDDYNNNQGDASSAIISYYAVDLKGNLTTNCNDDDI 517
Query: 403 NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSR-------SWANLYPEDDPS---- 257
NAVTWGVFP +E++QPTIV+ SF WKDE + ++S + A++ ED +
Sbjct: 518 NAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFSEWRKVLTSNLADVKDEDKKNLHKF 577
Query: 256 RKLLEEVKNSYYLVSLVDNNYINGD 182
KL+ E Y L +LV+N++I+ +
Sbjct: 578 EKLMTEFSEDYVLCNLVNNDFIDSN 602
[126][TOP]
>UniRef100_Q6CEM7 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CEM7_YARLI
Length = 625
Score = 102 bits (254), Expect = 2e-20
Identities = 52/127 (40%), Positives = 77/127 (60%), Gaps = 1/127 (0%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWV-SNTGESDVNAVTWGV 383
GGYV+QK++ EFF S ++ L A + V KS+ V +N E N VTWGV
Sbjct: 491 GGYVFQKSFAEFFISPEQWKKLKPLLDAQEDLVSYYVAKSDKLVDTNVSERASNGVTWGV 550
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP +E++Q TI+ SF W++EAF IWS W LY ++ S KLL+++ N Y LV+++
Sbjct: 551 FPNREIVQTTIIQEDSFDAWREEAFSIWS-EWRALYKKNTASFKLLDKIINEYLLVTVIH 609
Query: 202 NNYINGD 182
++Y+ D
Sbjct: 610 HDYVEED 616
[127][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 101 bits (252), Expect = 3e-20
Identities = 56/126 (44%), Positives = 76/126 (60%), Gaps = 4/126 (3%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKA-FPSITYMAVNKSENWVSN-TGESDVNAVTWGV 383
GYVYQK YLEF K L A FP++TY AV+ +N SN ++ NAVTWG+
Sbjct: 465 GYVYQKQYLEFLLPKHHLPAFHAALTADFPTLTYFAVDADDNLASNHPDDTQANAVTWGI 524
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDD--PSRKLLEEVKNSYYLVSL 209
FP +EV+QPTIV+ ASF WKDE + I W + E+ S LL + + Y LV++
Sbjct: 525 FPGREVLQPTIVEKASFLAWKDEFYRILD-DWRLSFDENGAADSAALLAHLTSDYALVNI 583
Query: 208 VDNNYI 191
VDN+++
Sbjct: 584 VDNDFV 589
[128][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 101 bits (252), Expect = 3e-20
Identities = 54/134 (40%), Positives = 85/134 (63%), Gaps = 5/134 (3%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE-SDVNAVTWGVF 380
GYVYQK YLEF +K++ L ++ +TY AV+ +N SN + S NAVTWG+F
Sbjct: 464 GYVYQKQYLEFLLPNEKVEKLEKQLAGNEMLTYFAVDNKDNLKSNHPDGSKANAVTWGIF 523
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDD--PSRKLLEEVKNSYYLVSLV 206
P +EV+QPTIV+ SF WK+E + I W + E++ S + ++ + ++Y LV++V
Sbjct: 524 PGREVLQPTIVEKVSFLAWKEEFYRI-LEEWKWNFQENNELKSAEFIQHIIDNYMLVNIV 582
Query: 205 DNNYING--DIFSV 170
DN+YI+ +I++V
Sbjct: 583 DNDYISSTDEIYNV 596
[129][TOP]
>UniRef100_Q5A5S8 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5A5S8_CANAL
Length = 640
Score = 101 bits (252), Expect = 3e-20
Identities = 51/128 (39%), Positives = 77/128 (60%), Gaps = 5/128 (3%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG-----ESDVNAVT 392
G +YQK+++E F K+ L+ K + ++TY NK SN + NAVT
Sbjct: 503 GIIYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVGNKDGEIKSNLPIGPNVKLSKNAVT 562
Query: 391 WGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP+KEV+QPT++D SFK W +EAF +W WA Y ++ S +LL + +Y LVS
Sbjct: 563 WGVFPSKEVVQPTVIDYESFKAWNEEAFLLW-LEWARCYKKNSKSFELLNSIYENYVLVS 621
Query: 211 LVDNNYIN 188
++ +++IN
Sbjct: 622 MIHHDFIN 629
[130][TOP]
>UniRef100_Q0UB79 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UB79_PHANO
Length = 543
Score = 101 bits (252), Expect = 3e-20
Identities = 48/125 (38%), Positives = 76/125 (60%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYV+QK ++EFF + L + A +TY A N + ++ +++ ES VN VTWG F
Sbjct: 413 GYVFQKPFVEFFLPAAEFHALRTRLDAHDQVTYFAGNANGDFEASSEES-VNPVTWGTFA 471
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
KE++ PTI++ SF+ W +EAF IW R W +YP S KLL + + +LV+++ +
Sbjct: 472 GKEIVTPTIIEAVSFRSWLEEAFSIW-REWQRIYPTKSASGKLLGQTREDVWLVNVIWGD 530
Query: 196 YINGD 182
++ GD
Sbjct: 531 FVQGD 535
[131][TOP]
>UniRef100_C4YKV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=C4YKV3_CANAL
Length = 640
Score = 101 bits (252), Expect = 3e-20
Identities = 51/128 (39%), Positives = 77/128 (60%), Gaps = 5/128 (3%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG-----ESDVNAVT 392
G +YQK+++E F K+ L+ K + ++TY NK SN + NAVT
Sbjct: 503 GIIYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVGNKDGEIKSNLPIGPNVKLSKNAVT 562
Query: 391 WGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP+KEV+QPT++D SFK W +EAF +W WA Y ++ S +LL + +Y LVS
Sbjct: 563 WGVFPSKEVVQPTVIDYESFKAWNEEAFLLW-LEWARCYKKNSKSFELLNSIYENYVLVS 621
Query: 211 LVDNNYIN 188
++ +++IN
Sbjct: 622 MIHHDFIN 629
[132][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 101 bits (252), Expect = 3e-20
Identities = 58/137 (42%), Positives = 84/137 (61%), Gaps = 16/137 (11%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTL---VEKSKA---FPSITYMAVNKSENWVSNTGESDVNAV 395
G+VYQK YLEF KDKL L VEK A + ITY AV+KS N +N+ D+NAV
Sbjct: 459 GFVYQKQYLEFLVRKDKLKELLDIVEKHNAKDTYGLITYYAVDKSGNLHTNSKNDDINAV 518
Query: 394 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEI---W-----SRSWANLYPEDDPSR--KLL 245
TWGVFP +E++QPTIV+ SF WKDE + + W S++ ++ PED ++ L+
Sbjct: 519 TWGVFPGEEILQPTIVEKVSFLAWKDEVYSLLDEWITIFHSKAITDIVPEDKINKFDDLI 578
Query: 244 EEVKNSYYLVSLVDNNY 194
+ ++ L + V+N++
Sbjct: 579 KSFGENFVLCNFVNNDF 595
[133][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 101 bits (252), Expect = 3e-20
Identities = 54/122 (44%), Positives = 75/122 (61%), Gaps = 1/122 (0%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDV-NAVTWGVF 380
GYV+QKAYLEFF D++ +L+E +F ++ Y + E + GE DV +AVTWGVF
Sbjct: 460 GYVFQKAYLEFFMHPDQVKSLLEVIPSFKTVQYY-ITDYEGSLETNGELDVPSAVTWGVF 518
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDN 200
P EVIQPT+V+ ASF WKDEA+ + SWA + KLL + + L +VDN
Sbjct: 519 PNSEVIQPTVVESASFLAWKDEAYSL-GLSWAKAHSSTSAPFKLLTNIVKEWKLCVIVDN 577
Query: 199 NY 194
++
Sbjct: 578 DF 579
[134][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 100 bits (250), Expect = 6e-20
Identities = 54/144 (37%), Positives = 79/144 (54%), Gaps = 21/144 (14%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPS---------ITYMAVNKSENWVSNTGESDV 404
GYVYQK YLEFF KD + L+ + + +TY AV++ SNT + D+
Sbjct: 457 GYVYQKQYLEFFVHKDIIPALLHQIDNYNRGQGDSNSSVLTYYAVDQKGKLFSNTKDDDI 516
Query: 403 NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED------------DP 260
NAVTWGVFP +E++QPTIV+ SF WKDE + + + W ++ D D
Sbjct: 517 NAVTWGVFPGEEILQPTIVEKVSFLAWKDEVYRLIT-EWIKIFQSDFVKDVNITKEDVDA 575
Query: 259 SRKLLEEVKNSYYLVSLVDNNYIN 188
KL+ + Y L ++V+NN+I+
Sbjct: 576 FVKLMTNFNDEYVLCNVVNNNFID 599
[135][TOP]
>UniRef100_C7YTQ6 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YTQ6_NECH7
Length = 674
Score = 100 bits (250), Expect = 6e-20
Identities = 53/138 (38%), Positives = 80/138 (57%), Gaps = 13/138 (9%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEK---SKAFPSITYMAVNKSENWVSNTGESDV------ 404
G+V+QK+++EFF + L EK S+ S+ + A N ++VS+ V
Sbjct: 530 GFVFQKSFVEFFIPSSEWSVLKEKLNSSELCDSVCFYAGNAKGDFVSSDKGGHVDGSSGA 589
Query: 403 ----NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
NAVTWGVFP KE+I PTI++ SF+ W +EAF IW WA +Y S KLL +
Sbjct: 590 GPSTNAVTWGVFPGKEIITPTIIEEVSFRAWCEEAFGIWG-EWAKVYGRGSDSEKLLSGI 648
Query: 235 KNSYYLVSLVDNNYINGD 182
K+ Y+LV+L+ ++++ D
Sbjct: 649 KDEYWLVNLIHHDFVEKD 666
[136][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 100 bits (250), Expect = 6e-20
Identities = 54/144 (37%), Positives = 79/144 (54%), Gaps = 21/144 (14%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPS---------ITYMAVNKSENWVSNTGESDV 404
GYVYQK YLEFF KD + L+ + + +TY AV++ SNT + D+
Sbjct: 457 GYVYQKQYLEFFVHKDIIPALLHQIDNYNRGQGDSNSSVLTYYAVDQKGKLFSNTKDDDI 516
Query: 403 NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED------------DP 260
NAVTWGVFP +E++QPTIV+ SF WKDE + + + W ++ D D
Sbjct: 517 NAVTWGVFPGEEILQPTIVEKVSFLAWKDEVYRLIT-EWIKIFQSDFVKDVNITKEDVDA 575
Query: 259 SRKLLEEVKNSYYLVSLVDNNYIN 188
KL+ + Y L ++V+NN+I+
Sbjct: 576 FVKLMTNFNDEYVLCNVVNNNFID 599
[137][TOP]
>UniRef100_A7TRT4 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TRT4_VANPO
Length = 645
Score = 100 bits (250), Expect = 6e-20
Identities = 54/128 (42%), Positives = 79/128 (61%), Gaps = 3/128 (2%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVE-KSKAFP--SITYMAVNKSENWVSNTGESDVNAVTWG 386
GYVYQKA++E F K + + +V+ K +P +Y + S ++ SN + N VTWG
Sbjct: 511 GYVYQKAFVEMFILKKQWEAIVKPKLDHYPRGKFSYYVGDSSGSFESNLETNSSNVVTWG 570
Query: 385 VFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLV 206
VFP VIQ TIV+ SFK W+DEAF IW WA L+P ++ S L++V ++Y LVS+V
Sbjct: 571 VFPNSPVIQTTIVEEESFKAWRDEAFCIW-LEWAKLFPSNELSNSFLKQVHSTYCLVSIV 629
Query: 205 DNNYINGD 182
+++ D
Sbjct: 630 HHDFSETD 637
[138][TOP]
>UniRef100_UPI000023F2EE hypothetical protein FG07127.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023F2EE
Length = 672
Score = 100 bits (249), Expect = 7e-20
Identities = 52/138 (37%), Positives = 80/138 (57%), Gaps = 13/138 (9%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEK---SKAFPSITYMAVNKSENWVSNT----------G 416
G+V+QK+++EFF ++ + L K S+ + + A N ++VS+
Sbjct: 528 GFVFQKSFVEFFIPANEWEILKAKLVSSELQDYVCFYASNARGDYVSSDIGGHVDGSTEA 587
Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
NAVTWGVFP KE+I PTI++ SF+ W +EAF IW WA +Y S KLL +
Sbjct: 588 SPSTNAVTWGVFPGKEIITPTIIEEVSFRAWCEEAFGIWG-EWAKVYGRGSESEKLLNGI 646
Query: 235 KNSYYLVSLVDNNYINGD 182
K+ Y+LV+L+ ++Y+N D
Sbjct: 647 KDDYWLVNLIHHDYVNRD 664
[139][TOP]
>UniRef100_Q6CR34 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CR34_KLULA
Length = 649
Score = 100 bits (248), Expect = 1e-19
Identities = 49/127 (38%), Positives = 77/127 (60%), Gaps = 2/127 (1%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPS--ITYMAVNKSENWVSNTGESDVNAVTWGV 383
G +YQKA++E F K++ + +++ + +Y + + + +N NAVTWGV
Sbjct: 516 GLIYQKAFVEIFVRKEEWNQVLKPKIESKNGEFSYYLGDYTGYFETNLQPKSSNAVTWGV 575
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP EV+Q TIV+ SFK W+DEAF IW W+ L+P++ P L ++ YYLVS+V
Sbjct: 576 FPNSEVVQTTIVEEESFKAWRDEAFSIWI-EWSKLFPKNTPENTFLRKMHRDYYLVSIVH 634
Query: 202 NNYINGD 182
+++IN D
Sbjct: 635 HDFINPD 641
[140][TOP]
>UniRef100_B9WCV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WCV3_CANDC
Length = 640
Score = 100 bits (248), Expect = 1e-19
Identities = 50/128 (39%), Positives = 77/128 (60%), Gaps = 5/128 (3%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSN-----TGESDVNAVT 392
G +YQK+++E F K+ L+ K + ++TY +K SN + NAVT
Sbjct: 503 GTIYQKSFIELFMPKEDWTKLLLKIELDKTVTYYVGDKDGEIRSNLPIGPNAKLSKNAVT 562
Query: 391 WGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP+KEV+QPT++D SFK W +EAF +W WA Y ++ S +LL + +Y LVS
Sbjct: 563 WGVFPSKEVVQPTVIDYESFKAWNEEAFLLWV-EWARCYKKNSKSFELLNSIYENYVLVS 621
Query: 211 LVDNNYIN 188
++ +++IN
Sbjct: 622 IIHHDFIN 629
[141][TOP]
>UniRef100_B2B6X0 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B6X0_PODAN
Length = 691
Score = 100 bits (248), Expect = 1e-19
Identities = 49/138 (35%), Positives = 82/138 (59%), Gaps = 13/138 (9%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSK---AFPSITYMAVNKSENWVSNTG---------- 416
G+V+QKA++EFF L +K + + + A+N + ++VS+
Sbjct: 547 GFVFQKAFVEFFIPSADWKVLEQKLRHPDLKDDVCFYAINAAGDFVSSDTAGSLEAEGEK 606
Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
E+ NAVTWGVFP KE++ PTI++ SF+ W +EAF IW WA +Y + S KLLE++
Sbjct: 607 EASTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWG-EWAKIYGKGSESEKLLEKI 665
Query: 235 KNSYYLVSLVDNNYINGD 182
+ +LV+++ +++I+ D
Sbjct: 666 RGDSWLVNIIHHDFIDSD 683
[142][TOP]
>UniRef100_C5GI01 Methylenetetrahydrofolate reductase n=2 Tax=Ajellomyces
dermatitidis RepID=C5GI01_AJEDR
Length = 713
Score = 99.4 bits (246), Expect = 2e-19
Identities = 50/148 (33%), Positives = 81/148 (54%), Gaps = 27/148 (18%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWVSNTGESD------- 407
G+V+QKA++EFFC+ L T+++ ++ + + A N + ++ S++ +D
Sbjct: 533 GFVFQKAFVEFFCTAHDLKTILKPIFENHGHDELAWFATNAAGDFESSSPPTDDSANDYS 592
Query: 406 -----------------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANL 278
VNAVTWGVF KE++ PTI++ SF+ W DEAF IW W +
Sbjct: 593 GPVDVYLDSNATAGGTGVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD-EWRRV 651
Query: 277 YPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
+P P+ KLL+++KN +LV +V Y
Sbjct: 652 FPRGSPTEKLLDQLKNDVWLVCVVGQKY 679
[143][TOP]
>UniRef100_A5DE00 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DE00_PICGU
Length = 642
Score = 99.4 bits (246), Expect = 2e-19
Identities = 55/130 (42%), Positives = 77/130 (59%), Gaps = 9/130 (6%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDT-LVEKSKAFPS---ITYMAVNKSENWVSNT-----GESDV 404
G+V+QK+++E F K++ T L K K ITY A + S SN +
Sbjct: 502 GFVFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDITYYAGDSSGKIQSNLPVGPDSHNSK 561
Query: 403 NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSY 224
NAVTWGVFP++EV+QPTI+D SF+ W +EAF +WS WA Y ++ S LL + Y
Sbjct: 562 NAVTWGVFPSQEVLQPTIIDIESFRAWNEEAFHLWS-EWARCYKKNSVSYNLLNSINGDY 620
Query: 223 YLVSLVDNNY 194
YLVSL+ +N+
Sbjct: 621 YLVSLIYHNF 630
[144][TOP]
>UniRef100_C9S7I3 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S7I3_9PEZI
Length = 312
Score = 98.6 bits (244), Expect = 3e-19
Identities = 47/100 (47%), Positives = 60/100 (60%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYVYQK+YLE D ++ + + P +TY AV KS N N NAVTWGVFP
Sbjct: 160 GYVYQKSYLEMLVHPDLYPEIISRIEKHPDMTYYAVTKSGNLKYNAPSDGPNAVTWGVFP 219
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 257
KE++QPTIV+ SF WKDEAF + WA+ + + PS
Sbjct: 220 GKEIVQPTIVEGISFVAWKDEAFRL-GLDWAHCFEQSSPS 258
[145][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 98.6 bits (244), Expect = 3e-19
Identities = 55/127 (43%), Positives = 77/127 (60%), Gaps = 4/127 (3%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESD-VNAVTWGVF 380
GYVYQK YLEF K+KL L + +TY AV+ + N +N + NAVTWG+F
Sbjct: 463 GYVYQKMYLEFLLPKEKLSKLHDCLVNDVMLTYFAVDHNGNLTTNHQDGTRANAVTWGIF 522
Query: 379 PAKEVIQPTIVDPASFKVWKDEAFEI---WSRSWANLYPEDDPSRKLLEEVKNSYYLVSL 209
P +EV+QPTIV+ SF WK E + I W ++ N D S KLL+ + + Y LV++
Sbjct: 523 PGREVLQPTIVEKVSFLAWKQEFYHICEEWKLNFIN--HRCDQSVKLLQHLIDDYVLVNI 580
Query: 208 VDNNYIN 188
VDN++I+
Sbjct: 581 VDNDFIS 587
[146][TOP]
>UniRef100_C5DPF1 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5DPF1_ZYGRC
Length = 650
Score = 97.8 bits (242), Expect = 5e-19
Identities = 52/130 (40%), Positives = 73/130 (56%), Gaps = 5/130 (3%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKD-----KLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVT 392
G VYQKA++E F K+ + +E+ +TY A + N+ +N + N VT
Sbjct: 515 GVVYQKAFIEMFVPKNIWENGNMKKAIEQYGR-AKLTYYANDSQGNFETNLESNSSNVVT 573
Query: 391 WGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVF +VIQ TIV SFK W DEAF IW WA L+P + + LL ++ Y L+S
Sbjct: 574 WGVFSDSQVIQSTIVSEESFKAWSDEAFSIW-LEWAKLFPRNTSTNSLLRQIHQEYCLIS 632
Query: 211 LVDNNYINGD 182
+V ++YIN D
Sbjct: 633 IVHHDYINPD 642
[147][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 97.4 bits (241), Expect = 6e-19
Identities = 48/124 (38%), Positives = 78/124 (62%), Gaps = 2/124 (1%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS-ITYMAVN-KSENWVSNTGESDVNAVTWG 386
GGY++QKA++E F +++ + LV+ + + +TY A + +N + +N VTWG
Sbjct: 453 GGYIFQKAFVELFMNENDKNALVQMIQGSSTPVTYFAGKCDPTTFETNLTTNGLNTVTWG 512
Query: 385 VFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLV 206
VFP EV Q TI++ ASF+ W+DEAF IW R W L+P + +R LL + + +LV++V
Sbjct: 513 VFPGTEVAQSTIIEEASFRAWRDEAFAIW-REWELLFPPNSATRSLLRRIHDERWLVTVV 571
Query: 205 DNNY 194
++Y
Sbjct: 572 HHDY 575
[148][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TTE9_VANPO
Length = 612
Score = 97.4 bits (241), Expect = 6e-19
Identities = 53/144 (36%), Positives = 83/144 (57%), Gaps = 19/144 (13%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEK----SKAFPSITYMAVNKSENWVSNTGE-SDVNAVT 392
GYVYQK YLEF + + + L ++ ++ S+TY+A + W SN + + AVT
Sbjct: 459 GYVYQKQYLEFLLPRARFERLQQELSKTNETTSSLTYLAADSHGGWWSNQPDGAKATAVT 518
Query: 391 WGVFPAKEVIQPTIVDPASFKVWKDEAFEI---WSRSWANLYPEDD-----------PSR 254
WGVFP +EV+QPTIV+ SF W+DE + I W + + P+ D PS
Sbjct: 519 WGVFPGREVLQPTIVEKISFLAWRDEFYRILQDWRDIFVHASPDGDQCDNGSAQRENPSA 578
Query: 253 KLLEEVKNSYYLVSLVDNNYINGD 182
KL++ + + Y LV+L+DN++++ D
Sbjct: 579 KLMQLMIDDYVLVNLIDNDFVSVD 602
[149][TOP]
>UniRef100_C5M548 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M548_CANTT
Length = 633
Score = 97.1 bits (240), Expect = 8e-19
Identities = 52/126 (41%), Positives = 77/126 (61%), Gaps = 5/126 (3%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGES-DV----NAVT 392
G VYQKA++E F KD + L +A SITY A +K+ + D+ NAVT
Sbjct: 496 GVVYQKAFVELFMPKDDWNKLKPLVEASDSITYYAADKTNKIEAKVPAGHDIKLTKNAVT 555
Query: 391 WGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP+KEV+QPT++D SFK W +E+F +W W+ Y ++ S +LL +V +Y LV
Sbjct: 556 WGVFPSKEVLQPTVIDYESFKAWNEESFLLW-LEWSRCYKKNSKSFELLNKVYENYVLVC 614
Query: 211 LVDNNY 194
L+ +++
Sbjct: 615 LIYHDF 620
[150][TOP]
>UniRef100_B2WHR5 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WHR5_PYRTR
Length = 653
Score = 96.7 bits (239), Expect = 1e-18
Identities = 46/125 (36%), Positives = 73/125 (58%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
GYV+QK ++EFF + K +A +T+ A N + + ++ E VN VTWG F
Sbjct: 523 GYVFQKPFVEFFIPAAEFQAFKPKLQAHDQVTWFAGNAAGAFEASQ-EDGVNPVTWGTFA 581
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
KE++ PTI++ SF+ W DEAF IW + W +YP S LL E+ +LV+++ +
Sbjct: 582 GKEIVTPTIIEAVSFRSWLDEAFSIW-KEWQRIYPPRSGSSVLLGELSKDVWLVNVIWGD 640
Query: 196 YINGD 182
++NG+
Sbjct: 641 FVNGE 645
[151][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1CZX0_NEOFI
Length = 716
Score = 96.7 bits (239), Expect = 1e-18
Identities = 49/136 (36%), Positives = 75/136 (55%), Gaps = 15/136 (11%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSENWVSNT----------- 419
G+V+QK ++EFFC T+++ A + + A N + S+
Sbjct: 556 GFVFQKPFVEFFCPSKDFQTVLKPLFAKHGHEKLAWFATNVKGEFESSLPADPAHADTIE 615
Query: 418 -GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
++VNAVTWGVF KE++ PTI++ SF+ W +EAF IW W +YP P+ +LLE
Sbjct: 616 MNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EWRRVYPRGTPTERLLE 674
Query: 241 EVKNSYYLVSLVDNNY 194
EVKN +LV +V ++
Sbjct: 675 EVKNDVWLVCVVGQDF 690
[152][TOP]
>UniRef100_UPI000151A866 hypothetical protein PGUG_01501 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151A866
Length = 642
Score = 96.3 bits (238), Expect = 1e-18
Identities = 54/130 (41%), Positives = 75/130 (57%), Gaps = 9/130 (6%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDT-LVEKSKAFPS---ITYMAVNKSENWVSNT-----GESDV 404
G+V+QK+++E F K++ T L K K ITY A + S SN +
Sbjct: 502 GFVFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDITYYAGDSSGKIQSNLPVGPDSHNSK 561
Query: 403 NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSY 224
NAVTWGVFP +EV+QPTI+D SF+ W +EAF +W WA Y ++ S LL + Y
Sbjct: 562 NAVTWGVFPLQEVLQPTIIDIESFRAWNEEAFHLW-LEWARCYKKNSVSYNLLNSINGDY 620
Query: 223 YLVSLVDNNY 194
YLVSL+ +N+
Sbjct: 621 YLVSLIYHNF 630
[153][TOP]
>UniRef100_Q7S2B6 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S2B6_NEUCR
Length = 681
Score = 96.3 bits (238), Expect = 1e-18
Identities = 53/150 (35%), Positives = 83/150 (55%), Gaps = 25/150 (16%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSENWVSN------------ 422
G+V+QKA++EFF L K K ++ + A N + ++VS
Sbjct: 525 GFVFQKAFVEFFIPSADWRVLEAKLKQPDMKDTVCFFATNAAGDFVSTDTINFRARMAAE 584
Query: 421 ---TGESD-------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYP 272
T E+D NAVTWGVFP KE++ PTI++ SF+ W +EAF IWS WA +Y
Sbjct: 585 AEGTAEADHRPHEPSTNAVTWGVFPGKEILTPTIIEEVSFRAWSEEAFGIWS-EWAKIYG 643
Query: 271 EDDPSRKLLEEVKNSYYLVSLVDNNYINGD 182
+ ++KLLE++K +LV+++ ++Y+ D
Sbjct: 644 KGSDTQKLLEDLKEDLWLVNVIHHDYLEKD 673
[154][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 96.3 bits (238), Expect = 1e-18
Identities = 53/127 (41%), Positives = 77/127 (60%), Gaps = 4/127 (3%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPS-ITYMAVNKSENWVSNTGE-SDVNAVTWGV 383
GYVYQK YLEF ++KL E + +TY A++ +N +N E S NAVTWGV
Sbjct: 466 GYVYQKEYLEFLLPREKLPLFQEICQEHSDHLTYFAIDSQDNLATNHPEDSRANAVTWGV 525
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED--DPSRKLLEEVKNSYYLVSL 209
FP E++QPTIV+ ASF WK+E F I + W + E S L+ + ++Y L+++
Sbjct: 526 FPGSEILQPTIVEKASFLAWKEEFFTI-LKEWKLTFVEHKATESVNLVNHIIDNYVLINV 584
Query: 208 VDNNYIN 188
VDN++I+
Sbjct: 585 VDNDFIS 591
[155][TOP]
>UniRef100_Q0CE17 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CE17_ASPTN
Length = 696
Score = 96.3 bits (238), Expect = 1e-18
Identities = 48/136 (35%), Positives = 76/136 (55%), Gaps = 15/136 (11%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWVSN----TGESD--- 407
G+V+QK ++EFFC T ++ + + + A N + ++ S+ T ++D
Sbjct: 537 GFVFQKPFVEFFCPTKDYQTALKPMLQKHGHEKLAWFATNANGDFESSLPAQTSDADPIE 596
Query: 406 -----VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
VNAVTWGVF KE++ PTI++ SF+ W DEA+ IW W +YP P+ + LE
Sbjct: 597 MNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWD-EWRRIYPRGSPTERFLE 655
Query: 241 EVKNSYYLVSLVDNNY 194
E KN +LV +V ++
Sbjct: 656 ETKNDVWLVCVVGQDF 671
[156][TOP]
>UniRef100_A7E9M9 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7E9M9_SCLS1
Length = 663
Score = 96.3 bits (238), Expect = 1e-18
Identities = 47/129 (36%), Positives = 79/129 (61%), Gaps = 4/129 (3%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEK--SKAF-PSITYMAVNKSENWVSNTGE-SDVNAVTW 389
G+V+QKA++E F + L K S A ++++ A N +++S+ NAVTW
Sbjct: 528 GFVFQKAFVELFLPTSDWEALQAKLTSPALRDTVSFYASNAKGDFISSDEAIGSTNAVTW 587
Query: 388 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSL 209
G FP KE+I PTI++ SF+ W +EAF IW WA +Y +D +RK+++ +K +LV++
Sbjct: 588 GAFPGKEIITPTIIEEVSFRAWAEEAFGIWG-EWARVYGKDSETRKVIDGIKEDVWLVNV 646
Query: 208 VDNNYINGD 182
+ + Y+ G+
Sbjct: 647 IHHAYVEGE 655
[157][TOP]
>UniRef100_A6RQJ7 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6RQJ7_BOTFB
Length = 663
Score = 96.3 bits (238), Expect = 1e-18
Identities = 46/129 (35%), Positives = 78/129 (60%), Gaps = 4/129 (3%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSENWVSNT-GESDVNAVTW 389
G+V+QKA++E F TL K + ++++ A N +++S+ NAVTW
Sbjct: 528 GFVFQKAFVELFIPVADWKTLHAKLTSPDLCDTVSFYASNAKGDFISSDEAVGSTNAVTW 587
Query: 388 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSL 209
G FP KE+I PTI++ SF+ W +EAF IW WA +Y +D +RK+++ +K +LV++
Sbjct: 588 GAFPGKEIITPTIIEEVSFRAWAEEAFGIWG-EWARVYGKDSQTRKIIDGIKEDVWLVNV 646
Query: 208 VDNNYINGD 182
+ + Y+ G+
Sbjct: 647 IHHAYVEGE 655
[158][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 95.9 bits (237), Expect = 2e-18
Identities = 49/136 (36%), Positives = 75/136 (55%), Gaps = 15/136 (11%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSENWVSNT----------- 419
G+V+QK ++EFFC T+++ A + + A N + S+
Sbjct: 529 GFVFQKPFVEFFCPSKDFRTVLKPLFAKHGHEKLAWFATNVKGEFESSLPADPAHADTIE 588
Query: 418 -GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
++VNAVTWGVF KE++ PTI++ SF+ W +EAF IW W +YP P+ +LLE
Sbjct: 589 MNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EWRRVYPRGTPTERLLE 647
Query: 241 EVKNSYYLVSLVDNNY 194
EVKN +LV +V ++
Sbjct: 648 EVKNDVWLVCVVGQDF 663
[159][TOP]
>UniRef100_C4R2L4 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2L4_PICPG
Length = 596
Score = 95.9 bits (237), Expect = 2e-18
Identities = 48/125 (38%), Positives = 78/125 (62%), Gaps = 2/125 (1%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKL-DTLVEKSKAFPSITYMAVNKSENWVSNTG-ESDVNAVTWGV 383
GYVYQKA++E F +K + + ++ + S+T+ + + + +N N+VTWG
Sbjct: 462 GYVYQKAFVEVFINKKQWNEEILPNLQGHKSVTWYLGDCNNAFDTNIKIPLSSNSVTWGC 521
Query: 382 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVD 203
FP KE++Q TI+ SF+ W +EAF IW R W LYP++ S LL + N++YLV+L++
Sbjct: 522 FPDKEIVQTTIIGEESFQAWNEEAFNIW-REWQKLYPKNTASYNLLGSIINNFYLVTLIN 580
Query: 202 NNYIN 188
++Y N
Sbjct: 581 HDYAN 585
[160][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 95.9 bits (237), Expect = 2e-18
Identities = 49/136 (36%), Positives = 75/136 (55%), Gaps = 15/136 (11%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSENWVSNT----------- 419
G+V+QK ++EFFC T+++ A + + A N + S+
Sbjct: 529 GFVFQKPFVEFFCPSKDFRTVLKPLFAKHGHEKLAWFATNVKGEFESSLPADPAHADTIE 588
Query: 418 -GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
++VNAVTWGVF KE++ PTI++ SF+ W +EAF IW W +YP P+ +LLE
Sbjct: 589 MNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EWRRVYPRGTPTERLLE 647
Query: 241 EVKNSYYLVSLVDNNY 194
EVKN +LV +V ++
Sbjct: 648 EVKNDVWLVCVVGQDF 663
[161][TOP]
>UniRef100_Q6BM19 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=Q6BM19_DEBHA
Length = 642
Score = 95.5 bits (236), Expect = 2e-18
Identities = 52/130 (40%), Positives = 74/130 (56%), Gaps = 9/130 (6%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKD----KLDTLVEKSKAFPSITYMAVNKSENWVSNTG-----ESDV 404
G +YQKA++E F KD KL ++K +ITY + SN +
Sbjct: 500 GIIYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTITYYCGDAEGRLTSNLNIDQEHYNSK 559
Query: 403 NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSY 224
NA+TWGVFP+KEV+QPTI+D SFK W +EAF +W WA Y + + +LL + Y
Sbjct: 560 NAITWGVFPSKEVLQPTIIDLESFKAWNEEAFILW-LEWARCYKKTSKTYELLNSIYKDY 618
Query: 223 YLVSLVDNNY 194
YLVSL+ +++
Sbjct: 619 YLVSLISHDF 628
[162][TOP]
>UniRef100_A4RH85 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RH85_MAGGR
Length = 662
Score = 95.5 bits (236), Expect = 2e-18
Identities = 51/145 (35%), Positives = 78/145 (53%), Gaps = 23/145 (15%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT-YMAVNKSENWVSNTGESDV-------- 404
G+V+QKA++E F L EK + + + A N ++ S+ G D
Sbjct: 508 GFVFQKAFVEMFLPSKDWKALREKLLSEKDVVCFYASNAKGDFESSDGGGDAPDGAPTGN 567
Query: 403 --------------NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 266
NAVTWGVFP KE++ PTI++ SF+ W +EAF IW+ WA +Y +D
Sbjct: 568 GFADEQPLPSGSSTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWA-EWAKVYGKD 626
Query: 265 DPSRKLLEEVKNSYYLVSLVDNNYI 191
PS KLLE ++ +LV+++ ++YI
Sbjct: 627 SPSEKLLESLRADLWLVNIIHHDYI 651
[163][TOP]
>UniRef100_C0NTN2 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NTN2_AJECG
Length = 713
Score = 95.1 bits (235), Expect = 3e-18
Identities = 46/148 (31%), Positives = 79/148 (53%), Gaps = 27/148 (18%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWVSNT----------- 419
G+V+QKA++EFFC +++++ +S + + A N + +++S++
Sbjct: 533 GFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNAAGDFMSSSPATDATTEDSS 592
Query: 418 -------------GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANL 278
G + V AVTWGVF KE++ PTI++ SF+ W DEAF IW W +
Sbjct: 593 GPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD-EWRRI 651
Query: 277 YPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
+P P+ +LL+++KN +L+ V Y
Sbjct: 652 FPRGSPTERLLDQLKNDVWLICCVGQKY 679
[164][TOP]
>UniRef100_A6QT35 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6QT35_AJECN
Length = 712
Score = 95.1 bits (235), Expect = 3e-18
Identities = 46/148 (31%), Positives = 79/148 (53%), Gaps = 27/148 (18%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWVSNT----------- 419
G+V+QKA++EFFC +++++ +S + + A N + +++S++
Sbjct: 532 GFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNAAGDFMSSSPATDAATEDFS 591
Query: 418 -------------GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANL 278
G + V AVTWGVF KE++ PTI++ SF+ W DEAF IW W +
Sbjct: 592 GPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD-EWRRI 650
Query: 277 YPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
+P P+ +LL+++KN +L+ V Y
Sbjct: 651 FPRGSPTERLLDQLKNDVWLICCVGQKY 678
[165][TOP]
>UniRef100_UPI00003BE162 hypothetical protein DEHA0F09867g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE162
Length = 642
Score = 94.7 bits (234), Expect = 4e-18
Identities = 52/130 (40%), Positives = 73/130 (56%), Gaps = 9/130 (6%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKD----KLDTLVEKSKAFPSITYMAVNKSENWVSNTG-----ESDV 404
G +YQKA++E F KD KL ++K +ITY + SN +
Sbjct: 500 GIIYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTITYYCGDAEGRLTSNLNIDQEHYNSK 559
Query: 403 NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSY 224
NA+TWGVFP KEV+QPTI+D SFK W +EAF +W WA Y + + +LL + Y
Sbjct: 560 NAITWGVFPLKEVLQPTIIDLESFKAWNEEAFILW-LEWARCYKKTSKTYELLNSIYKDY 618
Query: 223 YLVSLVDNNY 194
YLVSL+ +++
Sbjct: 619 YLVSLISHDF 628
[166][TOP]
>UniRef100_Q752W6 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q752W6_ASHGO
Length = 635
Score = 94.7 bits (234), Expect = 4e-18
Identities = 46/128 (35%), Positives = 73/128 (57%), Gaps = 2/128 (1%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS--ITYMAVNKSENWVSNTGESDVNAVTWG 386
GG VYQKA++E F K + + ++ P +Y + + ++ SN + VTWG
Sbjct: 501 GGVVYQKAFVELFVEKARWEAELKPRLEGPDSKFSYYFGDSAGSFASNMAPESSSVVTWG 560
Query: 385 VFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLV 206
VFP +++Q TI++ SFK W+DEAF IW SW+ L+P + P L + Y LVS+V
Sbjct: 561 VFPNSQILQTTIIEEESFKAWRDEAFSIW-LSWSKLFPRNSPHNAFLRGIHRDYCLVSIV 619
Query: 205 DNNYINGD 182
+++ + D
Sbjct: 620 HHDFSSVD 627
[167][TOP]
>UniRef100_C6HED8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6HED8_AJECH
Length = 713
Score = 94.7 bits (234), Expect = 4e-18
Identities = 46/148 (31%), Positives = 79/148 (53%), Gaps = 27/148 (18%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWVSNT----------- 419
G+V+QKA++EFFC +++++ +S + + A N + +++S++
Sbjct: 533 GFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNVAGDFMSSSPATDATTEDSS 592
Query: 418 -------------GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANL 278
G + V AVTWGVF KE++ PTI++ SF+ W DEAF IW W +
Sbjct: 593 GPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD-EWRRI 651
Query: 277 YPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
+P P+ +LL+++KN +L+ V Y
Sbjct: 652 FPRGSPTERLLDQLKNDVWLICCVGQKY 679
[168][TOP]
>UniRef100_Q1DT03 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DT03_COCIM
Length = 711
Score = 93.6 bits (231), Expect = 9e-18
Identities = 52/149 (34%), Positives = 76/149 (51%), Gaps = 28/149 (18%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDK----LDTLVEKSKAFPSITYMAVNKSENWVSNTGES------- 410
G+V+QKA++EFFCSKD L L+++ + A N + ++ S+T S
Sbjct: 535 GFVFQKAFVEFFCSKDDYRSHLKPLLQRY-GHDEFAWFATNAAGDFESSTSSSIPVPTGP 593
Query: 409 -----------------DVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWAN 281
VNAVTWGVF KE+I PTI++ SF+ W +EAF IW W
Sbjct: 594 VDAVFDDMDSFPSSNSGGVNAVTWGVFRGKEIITPTIIEEVSFRAWGEEAFRIWD-EWRR 652
Query: 280 LYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
++P P+ KLL VK +LV ++ +
Sbjct: 653 IFPRGSPTEKLLNRVKEDTWLVCVIGQRF 681
[169][TOP]
>UniRef100_C5P4Q4 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5P4Q4_COCP7
Length = 711
Score = 93.6 bits (231), Expect = 9e-18
Identities = 52/149 (34%), Positives = 76/149 (51%), Gaps = 28/149 (18%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDK----LDTLVEKSKAFPSITYMAVNKSENWVSNTGES------- 410
G+V+QKA++EFFCSKD L L+++ + A N + ++ S+T S
Sbjct: 535 GFVFQKAFVEFFCSKDDYRSHLKPLLQRY-GHDEFAWFATNAAGDFESSTSSSIPVPTGP 593
Query: 409 -----------------DVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWAN 281
VNAVTWGVF KE+I PTI++ SF+ W +EAF IW W
Sbjct: 594 VDAVFDDMDSFPSSNSGGVNAVTWGVFRGKEIITPTIIEEVSFRAWGEEAFRIWD-EWRR 652
Query: 280 LYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
++P P+ KLL VK +LV ++ +
Sbjct: 653 IFPRGSPTEKLLNRVKEDTWLVCVIGQRF 681
[170][TOP]
>UniRef100_A3LW82 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LW82_PICST
Length = 635
Score = 93.6 bits (231), Expect = 9e-18
Identities = 52/131 (39%), Positives = 79/131 (60%), Gaps = 10/131 (7%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFP-----SITYMAVNKSENWVSNT-----GESD 407
G VYQKA++E F K++ ++ + KS P +ITY + N SN +
Sbjct: 495 GIVYQKAFVEIFVPKEQWESEL-KSSLKPHFEEKTITYYVGDAEGNIESNLFVGPDAHNS 553
Query: 406 VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNS 227
NA+TWGVFP+KEV+QPTI+D SFK W +EAF +W WA Y ++ + +LL + ++
Sbjct: 554 KNAITWGVFPSKEVLQPTIIDYESFKAWNEEAFLLWI-EWARCYKKNTKTFQLLNSIYSN 612
Query: 226 YYLVSLVDNNY 194
Y LVSL+ +++
Sbjct: 613 YVLVSLIHHDF 623
[171][TOP]
>UniRef100_C8V780 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5AU15] n=2 Tax=Emericella
nidulans RepID=C8V780_EMENI
Length = 684
Score = 92.8 bits (229), Expect = 2e-17
Identities = 45/136 (33%), Positives = 74/136 (54%), Gaps = 15/136 (11%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWVSNT----------- 419
G+V+QK ++EFFC T ++ + + + A N + ++ S+
Sbjct: 525 GFVFQKPFVEFFCPASDFKTTLKPLLQKHGHEKLAWFATNAAGDFESSLPAETSDTEPVE 584
Query: 418 -GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
++VNAVTWGVF KE++ PTI++ SF+ W DEA+ IW W +YP+ + K LE
Sbjct: 585 MNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWD-EWRRIYPKSSATEKFLE 643
Query: 241 EVKNSYYLVSLVDNNY 194
+ KN +LV +V ++
Sbjct: 644 KTKNDVWLVCVVGQDF 659
[172][TOP]
>UniRef100_A2QUJ5 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QUJ5_ASPNC
Length = 699
Score = 92.4 bits (228), Expect = 2e-17
Identities = 49/137 (35%), Positives = 77/137 (56%), Gaps = 16/137 (11%)
Frame = -2
Query: 556 GYVYQKAYLEFFC-SKDKLDTL--VEKSKAFPSITYMAVNKSENWVS-----NTGESD-- 407
G+V+QK ++EFFC +KD L L + + + + A N ++ S NT + D
Sbjct: 538 GFVFQKPFVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNVKGDFESSLPGPNTDDPDPI 597
Query: 406 ------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLL 245
VNAVTWGVF KE++ PTI++ SF+ W DEA+ IW W +YP++ + + L
Sbjct: 598 DINPANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWD-EWRRIYPKNSATERFL 656
Query: 244 EEVKNSYYLVSLVDNNY 194
++ KN +LV +V +
Sbjct: 657 DDTKNDVWLVCVVGQEF 673
[173][TOP]
>UniRef100_C1H0K0 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1H0K0_PARBA
Length = 713
Score = 92.0 bits (227), Expect = 3e-17
Identities = 49/143 (34%), Positives = 78/143 (54%), Gaps = 22/143 (15%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWVSN------TGESD- 407
G+V+QKA++EFFCS + +++ K +++ A N S ++ S+ TG D
Sbjct: 537 GFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQSSSSFTGITGLDDA 596
Query: 406 ------------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDD 263
VNAVTWGVF KE+I PTI++ SF+ W DEAF IW W ++
Sbjct: 597 VPDYNGAASSNGVNAVTWGVFKGKEIITPTIIEEVSFRAWGDEAFRIWD-EWRRIFRRGS 655
Query: 262 PSRKLLEEVKNSYYLVSLVDNNY 194
P+ +LL+++K +L+ +V +
Sbjct: 656 PTEQLLDQLKKDAWLICVVGQKF 678
[174][TOP]
>UniRef100_A1C4Z1 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C4Z1_ASPCL
Length = 690
Score = 92.0 bits (227), Expect = 3e-17
Identities = 45/136 (33%), Positives = 75/136 (55%), Gaps = 15/136 (11%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEK---SKAFPSITYMAVNKSENWVSN----TGESD--- 407
G+V+QK ++EFFC +T+++ + + + A N + S+ T +SD
Sbjct: 530 GFVFQKPFVEFFCPSKDFETVLKPLFANHGHEKLAWFATNAKGEFQSSLPAETADSDALE 589
Query: 406 -----VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
VNAVTWGVF KE++ PTI++ SF+ W +EA+ IW W +YP + + ++
Sbjct: 590 PNPDNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAYRIW-EEWRRIYPRGSATERFID 648
Query: 241 EVKNSYYLVSLVDNNY 194
E KN +LV +V ++
Sbjct: 649 ETKNDVWLVCVVGQDF 664
[175][TOP]
>UniRef100_B6HK87 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6HK87_PENCW
Length = 691
Score = 90.5 bits (223), Expect = 8e-17
Identities = 46/138 (33%), Positives = 72/138 (52%), Gaps = 17/138 (12%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSENWVSN------------ 422
G+V+QK ++EFFCS + +++ A +T+ A N ++ S+
Sbjct: 528 GFVFQKPFVEFFCSSNDYTNILKPLFAKHGHDKLTWFATNVKGDFESSLPAQPADMDLDD 587
Query: 421 --TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKL 248
+ VNAVTWGVF KE++ PTI++ SF+ W +EAF IW W +YP P+
Sbjct: 588 LGSNPESVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EWRRIYPRGSPTETY 646
Query: 247 LEEVKNSYYLVSLVDNNY 194
L+ KN +LV +V +
Sbjct: 647 LDTTKNDSWLVCVVGQQF 664
[176][TOP]
>UniRef100_C7GU28 Met12p n=2 Tax=Saccharomyces cerevisiae RepID=C7GU28_YEAS2
Length = 657
Score = 90.1 bits (222), Expect = 1e-16
Identities = 48/128 (37%), Positives = 72/128 (56%), Gaps = 3/128 (2%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAF---PSITYMAVNKSENWVSNTGESDVNAVTWG 386
G +YQKA++E F + + +T ++ +Y A + S ++ +N + VTWG
Sbjct: 521 GRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWG 580
Query: 385 VFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLV 206
VFP V Q TI++ SFK W+DEAF IWS WA L+P + P+ LL V Y LVS+V
Sbjct: 581 VFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPANILLRLVHKDYCLVSIV 639
Query: 205 DNNYINGD 182
+++ D
Sbjct: 640 HHDFKETD 647
[177][TOP]
>UniRef100_B5VTD9 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VTD9_YEAS6
Length = 657
Score = 90.1 bits (222), Expect = 1e-16
Identities = 48/128 (37%), Positives = 72/128 (56%), Gaps = 3/128 (2%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAF---PSITYMAVNKSENWVSNTGESDVNAVTWG 386
G +YQKA++E F + + +T ++ +Y A + S ++ +N + VTWG
Sbjct: 521 GRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWG 580
Query: 385 VFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLV 206
VFP V Q TI++ SFK W+DEAF IWS WA L+P + P+ LL V Y LVS+V
Sbjct: 581 VFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPANILLRLVHKDYCLVSIV 639
Query: 205 DNNYINGD 182
+++ D
Sbjct: 640 HHDFKETD 647
[178][TOP]
>UniRef100_B3LL40 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LL40_YEAS1
Length = 657
Score = 90.1 bits (222), Expect = 1e-16
Identities = 48/128 (37%), Positives = 72/128 (56%), Gaps = 3/128 (2%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAF---PSITYMAVNKSENWVSNTGESDVNAVTWG 386
G +YQKA++E F + + +T ++ +Y A + S ++ +N + VTWG
Sbjct: 521 GRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWG 580
Query: 385 VFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLV 206
VFP V Q TI++ SFK W+DEAF IWS WA L+P + P+ LL V Y LVS+V
Sbjct: 581 VFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPANILLRLVHKDYCLVSIV 639
Query: 205 DNNYINGD 182
+++ D
Sbjct: 640 HHDFKETD 647
[179][TOP]
>UniRef100_P46151 Methylenetetrahydrofolate reductase 1 n=1 Tax=Saccharomyces
cerevisiae RepID=MTHR1_YEAST
Length = 657
Score = 90.1 bits (222), Expect = 1e-16
Identities = 48/128 (37%), Positives = 72/128 (56%), Gaps = 3/128 (2%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAF---PSITYMAVNKSENWVSNTGESDVNAVTWG 386
G +YQKA++E F + + +T ++ +Y A + S ++ +N + VTWG
Sbjct: 521 GRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWG 580
Query: 385 VFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLV 206
VFP V Q TI++ SFK W+DEAF IWS WA L+P + P+ LL V Y LVS+V
Sbjct: 581 VFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPANILLRLVHKDYCLVSIV 639
Query: 205 DNNYINGD 182
+++ D
Sbjct: 640 HHDFKETD 647
[180][TOP]
>UniRef100_A5DZ35 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DZ35_LODEL
Length = 622
Score = 89.7 bits (221), Expect = 1e-16
Identities = 52/126 (41%), Positives = 73/126 (57%), Gaps = 5/126 (3%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSN--TGESD---VNAVT 392
G VYQK+++E F L K + + TY +KS + T ES NAVT
Sbjct: 488 GVVYQKSFVELFIPAKDWKEL--KPRLDDATTYYVGDKSGRIELSLFTNESTRHLKNAVT 545
Query: 391 WGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP KEV+QPT++D SFK W +EAF +W WA Y ++ + +LL V+++Y LVS
Sbjct: 546 WGVFPLKEVVQPTVIDYESFKAWNEEAFLLW-LEWARCYKKNSKTYELLNSVRDNYVLVS 604
Query: 211 LVDNNY 194
L+ + Y
Sbjct: 605 LIHHEY 610
[181][TOP]
>UniRef100_Q2UA39 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus oryzae
RepID=Q2UA39_ASPOR
Length = 690
Score = 89.4 bits (220), Expect = 2e-16
Identities = 49/137 (35%), Positives = 78/137 (56%), Gaps = 16/137 (11%)
Frame = -2
Query: 556 GYVYQKAYLEFFC-SKDK---LDTLVEKSKAFPSITYMAVNKSENWVSN----TGESD-- 407
G+V+QK ++EFFC SKD L L++K + + A N ++ S+ T ++D
Sbjct: 529 GFVFQKPFVEFFCPSKDYHSILKPLLQKH-GHEKLAWFAANVKGDFESSLPAQTSDADPI 587
Query: 406 ------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLL 245
VN VTWGVF KE++ PTI++ SF+ W DEAF IW W +YP + + + L
Sbjct: 588 EMNPNNVNCVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD-EWRRIYPRNSATERFL 646
Query: 244 EEVKNSYYLVSLVDNNY 194
++K+ +LV +V ++
Sbjct: 647 NDIKDDVWLVCVVGQDF 663
[182][TOP]
>UniRef100_C9S8T9 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S8T9_9PEZI
Length = 670
Score = 89.4 bits (220), Expect = 2e-16
Identities = 44/134 (32%), Positives = 76/134 (56%), Gaps = 12/134 (8%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEK---SKAFPSITYMAVNKSENWVSNTGE--------- 413
G+V+QKA++E F L E+ + ++ + A N + ++ ++
Sbjct: 527 GFVFQKAFVELFLPAADWKVLSERLTGPEVEGTVCFYACNGNGDFATSDDSGGLVRTAVP 586
Query: 412 SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
+ NAVTWGVFP KE+I PTI++ SF+ W +EAF+IW W+ +Y S K L+ VK
Sbjct: 587 ASTNAVTWGVFPGKEIITPTIIEEVSFRAWSEEAFKIWG-EWSRVYGRGHESEKFLKTVK 645
Query: 232 NSYYLVSLVDNNYI 191
Y+LV+++ ++++
Sbjct: 646 EEYWLVNIIHHDFV 659
[183][TOP]
>UniRef100_C1GJU2 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1GJU2_PARBD
Length = 712
Score = 89.4 bits (220), Expect = 2e-16
Identities = 48/143 (33%), Positives = 77/143 (53%), Gaps = 22/143 (15%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWVSN------TGESD- 407
G+V+QKA++EFFCS + +++ K +++ A N S ++ S+ TG D
Sbjct: 537 GFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQSSSSFTGTTGLDDA 596
Query: 406 ------------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDD 263
VNAVTWGVF KE+I PTI++ SF+ W EAF IW W ++
Sbjct: 597 VPDYNGAASSNGVNAVTWGVFKGKEIITPTIIEEVSFRAWGHEAFRIWD-EWRRIFRRGS 655
Query: 262 PSRKLLEEVKNSYYLVSLVDNNY 194
P+ +LL+++K +L+ +V +
Sbjct: 656 PTEQLLDQLKKDAWLICVVGQKF 678
[184][TOP]
>UniRef100_C0S8C4 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0S8C4_PARBP
Length = 712
Score = 89.4 bits (220), Expect = 2e-16
Identities = 48/143 (33%), Positives = 77/143 (53%), Gaps = 22/143 (15%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWVSN------TGESD- 407
G+V+QKA++EFFCS + +++ K +++ A N S ++ S+ TG D
Sbjct: 537 GFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQSSSSFTGTTGLDDA 596
Query: 406 ------------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDD 263
VNAVTWGVF KE+I PTI++ SF+ W EAF IW W ++
Sbjct: 597 VPDYSGAASSNGVNAVTWGVFKGKEIITPTIIEEVSFRAWGHEAFRIWD-EWRRIFRRGS 655
Query: 262 PSRKLLEEVKNSYYLVSLVDNNY 194
P+ +LL+++K +L+ +V +
Sbjct: 656 PTEQLLDQLKKDAWLICVVGQKF 678
[185][TOP]
>UniRef100_B8NQE8 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus flavus
NRRL3357 RepID=B8NQE8_ASPFN
Length = 738
Score = 89.4 bits (220), Expect = 2e-16
Identities = 49/137 (35%), Positives = 78/137 (56%), Gaps = 16/137 (11%)
Frame = -2
Query: 556 GYVYQKAYLEFFC-SKDK---LDTLVEKSKAFPSITYMAVNKSENWVSN----TGESD-- 407
G+V+QK ++EFFC SKD L L++K + + A N ++ S+ T ++D
Sbjct: 577 GFVFQKPFVEFFCPSKDYHSILKPLLQKH-GHEKLAWFAANVKGDFESSLPAQTSDADPI 635
Query: 406 ------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLL 245
VN VTWGVF KE++ PTI++ SF+ W DEAF IW W +YP + + + L
Sbjct: 636 EMNPNNVNCVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD-EWRRIYPRNSATERFL 694
Query: 244 EEVKNSYYLVSLVDNNY 194
++K+ +LV +V ++
Sbjct: 695 NDIKDDVWLVCVVGQDF 711
[186][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 87.8 bits (216), Expect = 5e-16
Identities = 40/81 (49%), Positives = 54/81 (66%), Gaps = 1/81 (1%)
Frame = -2
Query: 559 GGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGV 383
GGYV+QKAYLEFF S++ + L++ K + + Y VN ++N E NAVTWG+
Sbjct: 534 GGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGI 593
Query: 382 FPAKEVIQPTIVDPASFKVWK 320
FP +E+IQPT+VDP SF WK
Sbjct: 594 FPGREIIQPTVVDPVSFMFWK 614
[187][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 87.8 bits (216), Expect = 5e-16
Identities = 47/149 (31%), Positives = 73/149 (48%), Gaps = 28/149 (18%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWVSNTG---------- 416
G+V+QKA++EFFC D + ++ S + A+N ++ S+T
Sbjct: 494 GFVFQKAFVEFFCPGDDFHSKLKPLLNSYGHDEFAWFAMNAKGDFQSSTSPEPPASPPTD 553
Query: 415 ---------------ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWAN 281
VNAVTWGVF KE++ PTI++ SF+ W +EAF IW W
Sbjct: 554 STEPLFDTDPLTDMDNGSVNAVTWGVFRGKEIVTPTIIEAVSFRAWGEEAFGIW-EEWRR 612
Query: 280 LYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
++P S KL+ +VK+ +LV +V +
Sbjct: 613 IFPRGSASEKLIRDVKDDVWLVCVVGQRF 641
[188][TOP]
>UniRef100_Q2HBA5 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2HBA5_CHAGB
Length = 643
Score = 86.3 bits (212), Expect = 1e-15
Identities = 42/125 (33%), Positives = 69/125 (55%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 377
G+V+QKA++EFF L ++ +N+ E E+ NAV+WGVFP
Sbjct: 529 GFVFQKAFVEFFLPLADWAALEKR-----------LNRPEMEGRREREASTNAVSWGVFP 577
Query: 376 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNN 197
KE++ PTI++ SF+ W +EAF IW W +Y + S + LE V +LV+++ ++
Sbjct: 578 GKEIVPPTIIEEVSFRAWSEEAFGIWG-EWVKIYEKGSESERFLERVLADTWLVNIIHHD 636
Query: 196 YINGD 182
++ D
Sbjct: 637 FLETD 641
[189][TOP]
>UniRef100_C4JM22 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JM22_UNCRE
Length = 709
Score = 84.3 bits (207), Expect = 6e-15
Identities = 46/148 (31%), Positives = 73/148 (49%), Gaps = 27/148 (18%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWVSNTGES-------- 410
G+V+QKA++EFFCS + + ++ + + A N + ++ ++T S
Sbjct: 533 GFVFQKAFVEFFCSSNDYRSYLKPLLQRYGHDEFAWFATNAAGDFEASTPPSAHSPTEPV 592
Query: 409 ----------------DVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANL 278
VNAVTWGVF KE+I PTI++ SF+ W +EAF IW W +
Sbjct: 593 DAGFEDPSSPAASNPGGVNAVTWGVFRGKEIITPTIIEEVSFRAWGEEAFRIWD-EWRRI 651
Query: 277 YPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
+ P+ KLL + K +LV +V +
Sbjct: 652 FARGSPTEKLLAQTKEDVWLVCVVGQRF 679
[190][TOP]
>UniRef100_B8MDD4 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8MDD4_TALSN
Length = 713
Score = 81.6 bits (200), Expect = 4e-14
Identities = 49/156 (31%), Positives = 72/156 (46%), Gaps = 30/156 (19%)
Frame = -2
Query: 556 GYVYQKAYLEFFC------SKDKLDTLVEKSKAF------------------------PS 467
G+V+QKA++EFFC +K K L S+ F P
Sbjct: 538 GFVFQKAFVEFFCPSSDYQNKVKPTLLKHGSEEFSWFAINAAGHLESSFLISTSSSPKPE 597
Query: 466 ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSW 287
T AV ++ ES AVTWG F +E+ PTI++ SF+ W +EAF IW W
Sbjct: 598 DTSSAVAAADEEPLEIRESTGMAVTWGAFRGREITTPTIIEEVSFRAWGEEAFRIWD-EW 656
Query: 286 ANLYPEDDPSRKLLEEVKNSYYLVSLVDNNYINGDI 179
+YP + +LL E KN +L+ ++ + Y G +
Sbjct: 657 RRIYPRGSATERLLNETKNDVWLLCVIGHRYGAGTV 692
[191][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 78.2 bits (191), Expect = 4e-13
Identities = 50/131 (38%), Positives = 72/131 (54%), Gaps = 10/131 (7%)
Frame = -2
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSENWV-------SNTGESDV- 404
GYV+QKAYLEFF S + + L++ K + P + Y VN ++ S+TG V
Sbjct: 499 GYVFQKAYLEFFTSSEMVTALIKVLKRYEPRVNYHIVNVHKHTQLLKLLSSSDTGMGPVI 558
Query: 403 -NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNS 227
NA G VI +I D DEAF +W WA LY E+ PSR +++ + ++
Sbjct: 559 QNAQDLGNL---SVIWISITD--------DEAFALWIEQWAKLYEEESPSRMIIQYIHDN 607
Query: 226 YYLVSLVDNNY 194
YYLV+LVDN++
Sbjct: 608 YYLVNLVDNDF 618
[192][TOP]
>UniRef100_B6QFH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QFH8_PENMQ
Length = 710
Score = 78.2 bits (191), Expect = 4e-13
Identities = 47/153 (30%), Positives = 73/153 (47%), Gaps = 32/153 (20%)
Frame = -2
Query: 556 GYVYQKAYLEFFC------SKDKLDTLVEKSKAFPSITYMAVNKSENWVSN--------- 422
G+V+QKA++EFFC +K K L S+ F ++ A+N + + S+
Sbjct: 536 GFVFQKAFVEFFCPNADYQNKVKPTLLKHGSEEF---SWFAINATGHLESSFLLSASSSP 592
Query: 421 -----------------TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSR 293
ES AVTWG F +E+ PTI++ SF+ W +EAF IW
Sbjct: 593 KPEDASSTIAADEEPVEVRESKGMAVTWGAFRGREITTPTIIEEVSFRAWGEEAFRIWD- 651
Query: 292 SWANLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
W +YP + +LL E KN +L+ ++ + Y
Sbjct: 652 EWRRIYPRGSATERLLNETKNDAWLLCVIGHRY 684