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[1][TOP]
>UniRef100_Q94AR8 3-isopropylmalate dehydratase n=1 Tax=Arabidopsis thaliana
RepID=LEUC_ARATH
Length = 509
Score = 309 bits (791), Expect = 1e-82
Identities = 148/149 (99%), Positives = 148/149 (99%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLV ATQKVWMDVYALPV
Sbjct: 361 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPV 420
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK
Sbjct: 421 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 480
Query: 264 EGQIYLASPYTAAASALTGRVADPREFLQ 178
EGQIYLASPYTAAASALTGRVADPREFLQ
Sbjct: 481 EGQIYLASPYTAAASALTGRVADPREFLQ 509
[2][TOP]
>UniRef100_UPI0001983BAD PREDICTED: similar to Os02g0125100 n=1 Tax=Vitis vinifera
RepID=UPI0001983BAD
Length = 508
Score = 293 bits (750), Expect = 8e-78
Identities = 137/149 (91%), Positives = 144/149 (96%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RECKDVKIDRVYIGSCTGGKTEDF+AAAK+FHA+G+KVKVPTFLV ATQKVWMDVY+LPV
Sbjct: 360 RECKDVKIDRVYIGSCTGGKTEDFLAAAKVFHASGKKVKVPTFLVPATQKVWMDVYSLPV 419
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
PG GGKTC+QIFEEAGCDTPASPSCGACLGGP DTYAR+NEPQVCVSTTNRNFPGRMGHK
Sbjct: 420 PGCGGKTCSQIFEEAGCDTPASPSCGACLGGPRDTYARMNEPQVCVSTTNRNFPGRMGHK 479
Query: 264 EGQIYLASPYTAAASALTGRVADPREFLQ 178
EGQIYLASPYTAAASALTG V DPREFLQ
Sbjct: 480 EGQIYLASPYTAAASALTGFVTDPREFLQ 508
[3][TOP]
>UniRef100_C0Z3H8 AT4G13430 protein n=1 Tax=Arabidopsis thaliana RepID=C0Z3H8_ARATH
Length = 175
Score = 292 bits (748), Expect = 1e-77
Identities = 140/141 (99%), Positives = 140/141 (99%)
Frame = -3
Query: 600 DRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGGKTC 421
DRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLV ATQKVWMDVYALPVPGAGGKTC
Sbjct: 35 DRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKTC 94
Query: 420 AQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYLAS 241
AQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYLAS
Sbjct: 95 AQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYLAS 154
Query: 240 PYTAAASALTGRVADPREFLQ 178
PYTAAASALTGRVADPREFLQ
Sbjct: 155 PYTAAASALTGRVADPREFLQ 175
[4][TOP]
>UniRef100_B9SQS5 3-isopropylmalate dehydratase, putative n=1 Tax=Ricinus communis
RepID=B9SQS5_RICCO
Length = 510
Score = 289 bits (739), Expect = 2e-76
Identities = 136/149 (91%), Positives = 143/149 (95%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RECKDVKIDRVYIGSCTGGKTEDFMAAAK+F A+G+KVKVPTFLV ATQKVWMDVY+LPV
Sbjct: 362 RECKDVKIDRVYIGSCTGGKTEDFMAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPV 421
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
PG+GGKTC+QIFEEAGCDTPASPSCGACLGGP DTYAR+NEP VCVSTTNRNFPGRMGHK
Sbjct: 422 PGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPMVCVSTTNRNFPGRMGHK 481
Query: 264 EGQIYLASPYTAAASALTGRVADPREFLQ 178
EGQIYLASPYTAAASALTG V DPREFLQ
Sbjct: 482 EGQIYLASPYTAAASALTGYVTDPREFLQ 510
[5][TOP]
>UniRef100_UPI0001983576 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI0001983576
Length = 508
Score = 285 bits (729), Expect = 2e-75
Identities = 132/148 (89%), Positives = 141/148 (95%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RECKDVKIDRVYIGSCTGGKTEDF+AAAK+FHA+G+KVKVPTFLV ATQKVWMDVY+LPV
Sbjct: 360 RECKDVKIDRVYIGSCTGGKTEDFLAAAKVFHASGKKVKVPTFLVPATQKVWMDVYSLPV 419
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
PG GGKTC+QIFEEAGCDTPASP+CGAC+GGP DTYAR+NEPQVCVSTTNRNFPGRMGHK
Sbjct: 420 PGCGGKTCSQIFEEAGCDTPASPTCGACMGGPRDTYARMNEPQVCVSTTNRNFPGRMGHK 479
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
E QIYLASPYTAAASAL G V DPREFL
Sbjct: 480 ESQIYLASPYTAAASALRGYVTDPREFL 507
[6][TOP]
>UniRef100_B9HSU8 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9HSU8_POPTR
Length = 462
Score = 285 bits (728), Expect = 3e-75
Identities = 134/149 (89%), Positives = 141/149 (94%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
REC+DVKIDRVYIGSCTGGKTEDFMA AK+F A+G+KVKVPTFLV ATQKVWMDVY LPV
Sbjct: 314 RECRDVKIDRVYIGSCTGGKTEDFMAVAKVFLASGKKVKVPTFLVPATQKVWMDVYTLPV 373
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
PG+GGKTCAQIFEEAGCDTPASPSCGACLGGP DT+AR+NEP VCVSTTNRNFPGRMGHK
Sbjct: 374 PGSGGKTCAQIFEEAGCDTPASPSCGACLGGPKDTHARMNEPMVCVSTTNRNFPGRMGHK 433
Query: 264 EGQIYLASPYTAAASALTGRVADPREFLQ 178
EGQIYLASPYTAAASALTG V DPREFLQ
Sbjct: 434 EGQIYLASPYTAAASALTGFVTDPREFLQ 462
[7][TOP]
>UniRef100_C5XT62 Putative uncharacterized protein Sb04g002120 n=1 Tax=Sorghum
bicolor RepID=C5XT62_SORBI
Length = 507
Score = 284 bits (727), Expect = 4e-75
Identities = 132/148 (89%), Positives = 142/148 (95%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RECKDVK+DRVYIGSCTGGKTEDF+AAAK+F A+G+KVKVPTFLV ATQKVWMDVY+LPV
Sbjct: 359 RECKDVKVDRVYIGSCTGGKTEDFLAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPV 418
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
PG+GGKTC+QIFEEAGCDTPASPSCGACLGGP DTYAR+NEP VCVSTTNRNFPGRMGHK
Sbjct: 419 PGSGGKTCSQIFEEAGCDTPASPSCGACLGGPRDTYARMNEPMVCVSTTNRNFPGRMGHK 478
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
EGQIYLASPYTAAASALTG V DPR+FL
Sbjct: 479 EGQIYLASPYTAAASALTGYVTDPRDFL 506
[8][TOP]
>UniRef100_C4JBG7 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=C4JBG7_MAIZE
Length = 505
Score = 284 bits (727), Expect = 4e-75
Identities = 133/148 (89%), Positives = 142/148 (95%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RECKDVKIDRVYIGSCTGGKTEDF+AAAK+F A+G+KVKVPTFLV ATQKVWMDVY+LPV
Sbjct: 357 RECKDVKIDRVYIGSCTGGKTEDFLAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPV 416
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
PG+GGKTCAQIFEEAGCDTPASP+CGACLGGP DTYAR+NEP VCVSTTNRNFPGRMGHK
Sbjct: 417 PGSGGKTCAQIFEEAGCDTPASPNCGACLGGPRDTYARMNEPTVCVSTTNRNFPGRMGHK 476
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
EGQIYLASPYTAAASALTG V DPR+FL
Sbjct: 477 EGQIYLASPYTAAASALTGYVTDPRDFL 504
[9][TOP]
>UniRef100_B6U6T6 3-isopropylmalate dehydratase large subunit 2 n=1 Tax=Zea mays
RepID=B6U6T6_MAIZE
Length = 504
Score = 283 bits (724), Expect = 8e-75
Identities = 132/148 (89%), Positives = 142/148 (95%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RECKDVKIDRVYIGSCTGGKTEDF+AAAKLF A+G+KVKVPTFLV ATQKVW+DVY+LPV
Sbjct: 356 RECKDVKIDRVYIGSCTGGKTEDFLAAAKLFLASGKKVKVPTFLVPATQKVWLDVYSLPV 415
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
PG+GGKTC+QIFEEAGCDTPASP+CGACLGGP DTYAR+NEP VCVSTTNRNFPGRMGHK
Sbjct: 416 PGSGGKTCSQIFEEAGCDTPASPNCGACLGGPRDTYARMNEPTVCVSTTNRNFPGRMGHK 475
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
EGQIYLASPYTAAASALTG V DPR+FL
Sbjct: 476 EGQIYLASPYTAAASALTGYVTDPRDFL 503
[10][TOP]
>UniRef100_C4IZQ5 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=C4IZQ5_MAIZE
Length = 505
Score = 283 bits (723), Expect = 1e-74
Identities = 132/148 (89%), Positives = 141/148 (95%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RECKDVKIDRVYIGSCTGGKTEDF+AA K+F A+G+KVKVPTFLV ATQKVWMDVY+LPV
Sbjct: 357 RECKDVKIDRVYIGSCTGGKTEDFLAAVKVFLASGKKVKVPTFLVPATQKVWMDVYSLPV 416
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
PG+GGKTCAQIFEEAGCDTPASP+CGACLGGP DTYAR+NEP VCVSTTNRNFPGRMGHK
Sbjct: 417 PGSGGKTCAQIFEEAGCDTPASPNCGACLGGPRDTYARMNEPTVCVSTTNRNFPGRMGHK 476
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
EGQIYLASPYTAAASALTG V DPR+FL
Sbjct: 477 EGQIYLASPYTAAASALTGYVTDPRDFL 504
[11][TOP]
>UniRef100_Q6Z702 Os02g0125100 protein n=2 Tax=Oryza sativa RepID=Q6Z702_ORYSJ
Length = 514
Score = 282 bits (722), Expect = 1e-74
Identities = 131/148 (88%), Positives = 141/148 (95%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RECKDVKIDRVYIGSCTGGKTEDF AAAK+F A+G+KVKVPTFLV ATQKVWMD+Y++PV
Sbjct: 366 RECKDVKIDRVYIGSCTGGKTEDFFAAAKVFLASGKKVKVPTFLVPATQKVWMDIYSIPV 425
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
PGAGGKTC+QIFEEAGCDTPASPSCGACLGGP DTYAR+NEP VCVSTTNRNFPGRMGHK
Sbjct: 426 PGAGGKTCSQIFEEAGCDTPASPSCGACLGGPRDTYARMNEPMVCVSTTNRNFPGRMGHK 485
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
EGQIYLASP+TAAASALTG V DPR+FL
Sbjct: 486 EGQIYLASPFTAAASALTGYVTDPRDFL 513
[12][TOP]
>UniRef100_B4FG11 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=B4FG11_MAIZE
Length = 505
Score = 281 bits (720), Expect = 2e-74
Identities = 130/148 (87%), Positives = 142/148 (95%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RECKDVKIDRVYIGSCTGGKTEDF+AAAK+F A+G+KVKVPTFLV ATQKVW+D+Y+LPV
Sbjct: 357 RECKDVKIDRVYIGSCTGGKTEDFLAAAKVFLASGKKVKVPTFLVPATQKVWLDIYSLPV 416
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
PG+GGKTC+QIFEEAGCDTPASP+CGACLGGP DTYAR+NEP VCVSTTNRNFPGRMGHK
Sbjct: 417 PGSGGKTCSQIFEEAGCDTPASPNCGACLGGPRDTYARMNEPTVCVSTTNRNFPGRMGHK 476
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
EGQIYLASPYTAAASALTG V DPR+FL
Sbjct: 477 EGQIYLASPYTAAASALTGYVTDPRDFL 504
[13][TOP]
>UniRef100_B9SQS6 3-isopropylmalate dehydratase, putative n=1 Tax=Ricinus communis
RepID=B9SQS6_RICCO
Length = 621
Score = 280 bits (715), Expect = 9e-74
Identities = 130/149 (87%), Positives = 140/149 (93%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RECKDVKIDRVYIGSCTGGKTEDF AAAK+F A+G+KVKVPTFLV ATQKVWMDVY++PV
Sbjct: 473 RECKDVKIDRVYIGSCTGGKTEDFTAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSIPV 532
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
PG+GGKTC++IFEEAGCDTPASP C AC+GGP DTYAR+NEP VCVSTTNRNFPGRMGHK
Sbjct: 533 PGSGGKTCSRIFEEAGCDTPASPGCSACMGGPRDTYARMNEPMVCVSTTNRNFPGRMGHK 592
Query: 264 EGQIYLASPYTAAASALTGRVADPREFLQ 178
EGQIYLASPYTAAASALTG V DPREFLQ
Sbjct: 593 EGQIYLASPYTAAASALTGYVTDPREFLQ 621
[14][TOP]
>UniRef100_B9HKV5 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9HKV5_POPTR
Length = 443
Score = 278 bits (710), Expect = 3e-73
Identities = 129/149 (86%), Positives = 141/149 (94%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RECKDVKIDRVYIGSCTGGKTEDFMAAAK+F A+G+KV+VPTFLV AT KVWMD+Y LPV
Sbjct: 295 RECKDVKIDRVYIGSCTGGKTEDFMAAAKVFLASGKKVRVPTFLVPATGKVWMDLYTLPV 354
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
PG+GGKTC+QIFEEAGCDTPA+P+CGAC+GGP DTYAR+N+P VCVSTTNRNFPGRMGHK
Sbjct: 355 PGSGGKTCSQIFEEAGCDTPANPTCGACMGGPRDTYARMNKPVVCVSTTNRNFPGRMGHK 414
Query: 264 EGQIYLASPYTAAASALTGRVADPREFLQ 178
EGQIYLASPYTAAASALTG V DPREFLQ
Sbjct: 415 EGQIYLASPYTAAASALTGFVTDPREFLQ 443
[15][TOP]
>UniRef100_A5AN38 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5AN38_VITVI
Length = 252
Score = 275 bits (702), Expect = 3e-72
Identities = 136/182 (74%), Positives = 143/182 (78%), Gaps = 33/182 (18%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RECKDVKIDRVYIGSCTGGKTEDF+AAAK+FH +G+KVKVPTFLV ATQKVWMDVY+LPV
Sbjct: 71 RECKDVKIDRVYIGSCTGGKTEDFLAAAKVFHVSGKKVKVPTFLVPATQKVWMDVYSLPV 130
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQ----------------- 316
PG GGKTC+QIFEEAGCDTPASPSCGACLGGP DTYAR+NEPQ
Sbjct: 131 PGCGGKTCSQIFEEAGCDTPASPSCGACLGGPRDTYARMNEPQATFGCGWIPFFFGHGGC 190
Query: 315 ----------------VCVSTTNRNFPGRMGHKEGQIYLASPYTAAASALTGRVADPREF 184
VCVSTTNRNFPGRMGHKEGQIYLASPYTAAASALTG V DPREF
Sbjct: 191 MINYLMILDLLYLHLKVCVSTTNRNFPGRMGHKEGQIYLASPYTAAASALTGFVTDPREF 250
Query: 183 LQ 178
LQ
Sbjct: 251 LQ 252
[16][TOP]
>UniRef100_C0PRG9 Putative uncharacterized protein n=1 Tax=Picea sitchensis
RepID=C0PRG9_PICSI
Length = 237
Score = 274 bits (700), Expect = 5e-72
Identities = 128/148 (86%), Positives = 137/148 (92%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
REC+ +KIDRVYIGSCTGGKTEDFMAAAK+ +AG+KVKVPTFLV ATQKVWMD+Y LPV
Sbjct: 90 RECRHIKIDRVYIGSCTGGKTEDFMAAAKILISAGQKVKVPTFLVPATQKVWMDLYTLPV 149
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
PG GKTCAQIFEEAGCDTPASP+CGACLGGP DTYAR+N PQVCVSTTNRNFPGRMGHK
Sbjct: 150 PGGNGKTCAQIFEEAGCDTPASPNCGACLGGPRDTYARMNVPQVCVSTTNRNFPGRMGHK 209
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
EGQIYLASPYTAAASALTG V DPR+FL
Sbjct: 210 EGQIYLASPYTAAASALTGFVTDPRDFL 237
[17][TOP]
>UniRef100_B8LQY6 Putative uncharacterized protein n=1 Tax=Picea sitchensis
RepID=B8LQY6_PICSI
Length = 515
Score = 274 bits (700), Expect = 5e-72
Identities = 128/148 (86%), Positives = 137/148 (92%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
REC+ +KIDRVYIGSCTGGKTEDFMAAAK+ +AG+KVKVPTFLV ATQKVWMD+Y LPV
Sbjct: 368 RECRHIKIDRVYIGSCTGGKTEDFMAAAKILISAGQKVKVPTFLVPATQKVWMDLYTLPV 427
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
PG GKTCAQIFEEAGCDTPASP+CGACLGGP DTYAR+N PQVCVSTTNRNFPGRMGHK
Sbjct: 428 PGGNGKTCAQIFEEAGCDTPASPNCGACLGGPRDTYARMNVPQVCVSTTNRNFPGRMGHK 487
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
EGQIYLASPYTAAASALTG V DPR+FL
Sbjct: 488 EGQIYLASPYTAAASALTGFVTDPRDFL 515
[18][TOP]
>UniRef100_A9TGU1 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9TGU1_PHYPA
Length = 518
Score = 273 bits (697), Expect = 1e-71
Identities = 127/148 (85%), Positives = 138/148 (93%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RECKDVKIDRVYIGSCTGGKTEDF+AAA+L +G+KVKVPTFLV ATQKVWMD+Y+LPV
Sbjct: 371 RECKDVKIDRVYIGSCTGGKTEDFLAAAELLAISGQKVKVPTFLVPATQKVWMDLYSLPV 430
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
PG GKTCA+IF++AGCDTPASPSC ACLGGP DTYAR+N+PQVCVSTTNRNFPGRMGHK
Sbjct: 431 PGTDGKTCAEIFQQAGCDTPASPSCAACLGGPRDTYARMNDPQVCVSTTNRNFPGRMGHK 490
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
EGQIYLASPYTAAASALTG V DPREFL
Sbjct: 491 EGQIYLASPYTAAASALTGFVTDPREFL 518
[19][TOP]
>UniRef100_B8LQ24 Putative uncharacterized protein n=1 Tax=Picea sitchensis
RepID=B8LQ24_PICSI
Length = 516
Score = 271 bits (694), Expect = 2e-71
Identities = 126/148 (85%), Positives = 137/148 (92%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
REC+ +KIDRVYIGSCTGGKTEDFMAAAK+ +AG+KVKVPTFLV ATQKVWMD+Y LPV
Sbjct: 369 RECRHIKIDRVYIGSCTGGKTEDFMAAAKIMISAGQKVKVPTFLVPATQKVWMDLYTLPV 428
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
PG GKTC+QIFEEAGCDTPA+P+CGACLGGP DTYAR+N PQVCVSTTN+NFPGRMGHK
Sbjct: 429 PGGNGKTCSQIFEEAGCDTPANPNCGACLGGPRDTYARMNVPQVCVSTTNKNFPGRMGHK 488
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
EGQIYLASPYTAAASALTG V DPREFL
Sbjct: 489 EGQIYLASPYTAAASALTGFVTDPREFL 516
[20][TOP]
>UniRef100_B6TYJ6 3-isopropylmalate dehydratase large subunit 2 n=1 Tax=Zea mays
RepID=B6TYJ6_MAIZE
Length = 492
Score = 266 bits (680), Expect = 1e-69
Identities = 124/136 (91%), Positives = 132/136 (97%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RECKDVKIDRVYIGSCTGGKTEDF+AAAK+F A+G+KVKVPTFLV ATQKVWMDVY+LPV
Sbjct: 357 RECKDVKIDRVYIGSCTGGKTEDFLAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPV 416
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
PG+GGKTCAQIFEEAGCDTPASP+CGACLGGP DTYAR+NEP VCVSTTNRNFPGRMGHK
Sbjct: 417 PGSGGKTCAQIFEEAGCDTPASPNCGACLGGPRDTYARMNEPTVCVSTTNRNFPGRMGHK 476
Query: 264 EGQIYLASPYTAAASA 217
EGQIYLASPYTAAASA
Sbjct: 477 EGQIYLASPYTAAASA 492
[21][TOP]
>UniRef100_A8JG03 Isopropylmalate dehydratase, large subunit n=1 Tax=Chlamydomonas
reinhardtii RepID=A8JG03_CHLRE
Length = 487
Score = 256 bits (655), Expect = 8e-67
Identities = 119/148 (80%), Positives = 133/148 (89%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
REC DVKIDRVYIGSCTGGKTEDF++AAKLF+ A R+VKVPT+LV ATQKVW DVY +PV
Sbjct: 340 RECSDVKIDRVYIGSCTGGKTEDFISAAKLFYRAKRQVKVPTYLVPATQKVWADVYTMPV 399
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
PG GKT A+IFEE+GC TPA+PSC ACLGGP DT+AR+NEP+VCVSTTNRNFPGRMGHK
Sbjct: 400 PGCDGKTAAEIFEESGCITPAAPSCAACLGGPRDTFARMNEPEVCVSTTNRNFPGRMGHK 459
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
EGQIYLASPYTAAASAL G V DPRE++
Sbjct: 460 EGQIYLASPYTAAASALKGFVCDPREYM 487
[22][TOP]
>UniRef100_Q111B2 Homoaconitate hydratase family protein n=1 Tax=Trichodesmium
erythraeum IMS101 RepID=Q111B2_TRIEI
Length = 439
Score = 207 bits (528), Expect = 4e-52
Identities = 101/148 (68%), Positives = 120/148 (81%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
R C+DVKIDRVYIGSCTGGKT DF+ AAKL +VKVPT+LV ATQKV+ D++ +
Sbjct: 297 RNCQDVKIDRVYIGSCTGGKTSDFLHAAKLIK--DHQVKVPTYLVPATQKVYEDLFIIK- 353
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
GKT ++IF +AGC PA+PSC ACLGGP DT+ RLNEP++CVSTTNRNFPGRMG+K
Sbjct: 354 --HDGKTLSEIFLDAGCIEPAAPSCAACLGGPKDTFGRLNEPEICVSTTNRNFPGRMGNK 411
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
+ Q+YLASPYTAAASALTG V DPREF+
Sbjct: 412 QAQVYLASPYTAAASALTGYVTDPREFM 439
[23][TOP]
>UniRef100_A7QRJ3 Chromosome chr8 scaffold_150, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7QRJ3_VITVI
Length = 424
Score = 207 bits (526), Expect = 8e-52
Identities = 94/111 (84%), Positives = 103/111 (92%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RECKDVKIDRVYIGSCTGGKTEDF+AAAK+FHA+G+KVKVPTFLV ATQKVWMDVY+LPV
Sbjct: 314 RECKDVKIDRVYIGSCTGGKTEDFLAAAKVFHASGKKVKVPTFLVPATQKVWMDVYSLPV 373
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNR 292
PG GGKTC+QIFEEAGCDTPASPSCGACLGGP DTYAR+NEPQ + N+
Sbjct: 374 PGCGGKTCSQIFEEAGCDTPASPSCGACLGGPRDTYARMNEPQASMRLYNK 424
[24][TOP]
>UniRef100_A7NXJ3 Chromosome chr5 scaffold_2, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7NXJ3_VITVI
Length = 507
Score = 203 bits (517), Expect = 8e-51
Identities = 91/103 (88%), Positives = 100/103 (97%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RECKDVKIDRVYIGSCTGGKTEDF+AAAK+FHA+G+KVKVPTFLV ATQKVWMDVY+LPV
Sbjct: 377 RECKDVKIDRVYIGSCTGGKTEDFLAAAKVFHASGKKVKVPTFLVPATQKVWMDVYSLPV 436
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQ 316
PG GGKTC+QIFEEAGCDTPASP+CGAC+GGP DTYAR+NEPQ
Sbjct: 437 PGCGGKTCSQIFEEAGCDTPASPTCGACMGGPRDTYARMNEPQ 479
[25][TOP]
>UniRef100_A9PBQ8 Putative uncharacterized protein n=1 Tax=Populus trichocarpa
RepID=A9PBQ8_POPTR
Length = 97
Score = 186 bits (472), Expect = 1e-45
Identities = 84/97 (86%), Positives = 92/97 (94%)
Frame = -3
Query: 468 MDVYALPVPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRN 289
MD+Y LPVPG+GGKTC+QIFEEAGCDTPA+P+CGAC+GGP DTYAR+N+P VCVSTTNRN
Sbjct: 1 MDLYTLPVPGSGGKTCSQIFEEAGCDTPANPTCGACMGGPRDTYARMNKPVVCVSTTNRN 60
Query: 288 FPGRMGHKEGQIYLASPYTAAASALTGRVADPREFLQ 178
FPGRMGHKEGQIYLASPYTAAASALTG V DPREFLQ
Sbjct: 61 FPGRMGHKEGQIYLASPYTAAASALTGFVTDPREFLQ 97
[26][TOP]
>UniRef100_C4C1N1 Homoaconitate hydratase family protein/3-isopropylmalate
dehydratase, large subunit n=1 Tax=Sebaldella termitidis
ATCC 33386 RepID=C4C1N1_9FUSO
Length = 435
Score = 171 bits (432), Expect = 6e-41
Identities = 86/144 (59%), Positives = 106/144 (73%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
DVK+DR YIGSCTGGKT DF+AAAK+ GRKV + TF+V +T KV + + + G
Sbjct: 294 DVKLDRAYIGSCTGGKTTDFVAAAKILK--GRKVAIETFIVPSTVKVEEALSKIIIDG-- 349
Query: 432 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
+TC +IFE+AGC PSC ACLGGP DT+ R + +V +STTNRNFPGRMG + Q+
Sbjct: 350 -ETCMEIFEKAGCKI-GPPSCAACLGGPVDTFGRTHANEVVISTTNRNFPGRMGSMDSQV 407
Query: 252 YLASPYTAAASALTGRVADPREFL 181
YLASPYTAAASA+TG + DPREFL
Sbjct: 408 YLASPYTAAASAVTGHITDPREFL 431
[27][TOP]
>UniRef100_B4D0Q5 Aconitate hydratase domain protein n=1 Tax=Chthoniobacter flavus
Ellin428 RepID=B4D0Q5_9BACT
Length = 456
Score = 162 bits (409), Expect = 3e-38
Identities = 82/148 (55%), Positives = 100/148 (67%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
+E V +DR YIGSCTGGKT DF+A A++ G+ VK+ TF V AT KV V L
Sbjct: 313 KELAGVSLDRAYIGSCTGGKTSDFLAFARV--VKGKSVKIDTFGVPATTKV---VQELKD 367
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
G++ I E AG + SC ACLGGP DT+ R+N P C+S TNRNFPGRMGHK
Sbjct: 368 TQWDGQSVWNILESAGVRMTENASCAACLGGPVDTFGRMNTPLKCISATNRNFPGRMGHK 427
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
E Q++LASPYT AASALTG++ DPREF+
Sbjct: 428 ESQVFLASPYTVAASALTGKITDPREFI 455
[28][TOP]
>UniRef100_A1BES2 Homoaconitate hydratase family protein n=1 Tax=Chlorobium
phaeobacteroides DSM 266 RepID=A1BES2_CHLPD
Length = 431
Score = 158 bits (400), Expect = 3e-37
Identities = 86/148 (58%), Positives = 102/148 (68%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
R + I R YIGSCTGGK DFM AAK+ + G+KV VPT +V AT KV D L +
Sbjct: 290 RSVQGTAITRSYIGSCTGGKLSDFMMAAKILN--GKKVSVPTNIVPATVKVAAD---LAI 344
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
G+T QIFE+AGC A PSC ACLGGP+DT R + V VSTTNRNFPGRMG K
Sbjct: 345 EQYEGRTLKQIFEDAGCSI-ALPSCAACLGGPSDTVGRSVDNDVVVSTTNRNFPGRMGSK 403
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
+ +YLASP TAAASA+TG++ DPR+FL
Sbjct: 404 KAGVYLASPLTAAASAITGKLTDPRDFL 431
[29][TOP]
>UniRef100_B9XBH0 Aconitate hydratase domain protein n=1 Tax=bacterium Ellin514
RepID=B9XBH0_9BACT
Length = 455
Score = 158 bits (400), Expect = 3e-37
Identities = 78/143 (54%), Positives = 98/143 (68%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
DVK+DR YIGSCTGGKT DF+ A++ G++V + TF V AT ++ V+ L G
Sbjct: 316 DVKLDRAYIGSCTGGKTSDFLEFARVLK--GKRVMIDTFGVPATPEI---VHDLQTARWG 370
Query: 432 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
KT QI +AG + C ACLGGP DT+ R+N P C+S TNRNFPGRMGHKE Q+
Sbjct: 371 EKTVWQILVDAGVQMTENAGCAACLGGPVDTFGRMNTPMKCISATNRNFPGRMGHKESQV 430
Query: 252 YLASPYTAAASALTGRVADPREF 184
+LASP T AASALTG++ DPRE+
Sbjct: 431 FLASPATVAASALTGKITDPREY 453
[30][TOP]
>UniRef100_UPI00016C35D3 homoaconitate hydratase family protein n=1 Tax=Gemmata
obscuriglobus UQM 2246 RepID=UPI00016C35D3
Length = 435
Score = 156 bits (394), Expect = 2e-36
Identities = 82/147 (55%), Positives = 99/147 (67%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
+ K K+DR YIGSCTGGK DF AAA+L + G+ VK+ TF+V AT +V L
Sbjct: 294 QVKGTKLDRAYIGSCTGGKLTDFKAAAQLLN--GKTVKIDTFVVPATTEV---ARGLDTE 348
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
GG++ IF AG SC ACLGGP+DT+ RLN P C+STTNRNFPGRMGHK+
Sbjct: 349 TIGGRSLRDIFLSAGAKI-GDASCAACLGGPSDTFGRLNAPISCISTTNRNFPGRMGHKD 407
Query: 261 GQIYLASPYTAAASALTGRVADPREFL 181
Q++LASP T AASALTG +AD RE L
Sbjct: 408 AQVFLASPLTVAASALTGTIADCRELL 434
[31][TOP]
>UniRef100_B3E0P6 3-isopropylmalate dehydratase large subunit n=1
Tax=Methylacidiphilum infernorum V4 RepID=B3E0P6_METI4
Length = 455
Score = 155 bits (393), Expect = 2e-36
Identities = 77/148 (52%), Positives = 99/148 (66%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
+E VKIDR Y+GSCTGGK DF+A A + R V V TF V +T +V ++ + +
Sbjct: 313 KELGSVKIDRAYLGSCTGGKLSDFIAFASILK--NRTVSVETFAVPSTPEVVDQLHKIEI 370
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
G K+ EAG +PSC ACLGGP DT+ R+N+P VC+S+TNRNFPGRMG K
Sbjct: 371 EG---KSIWDTLREAGVQITENPSCAACLGGPMDTFGRVNKPLVCISSTNRNFPGRMGDK 427
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
Q+YLASP T A+SA+TG++ DPREFL
Sbjct: 428 SSQVYLASPLTVASSAITGKITDPREFL 455
[32][TOP]
>UniRef100_B4SDL0 Homoaconitate hydratase family protein n=1 Tax=Pelodictyon
phaeoclathratiforme BU-1 RepID=B4SDL0_PELPB
Length = 431
Score = 152 bits (385), Expect = 2e-35
Identities = 86/148 (58%), Positives = 99/148 (66%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
R + KI + YIGSCTGGK DFM AAK+ G KV V T +V AT KV D L
Sbjct: 290 RSVQGTKITKSYIGSCTGGKLTDFMMAAKILK--GHKVSVTTNIVPATVKVARD---LEC 344
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
G++ QIFE+AGC T A PSC ACLGGPADT R + V VSTTNRNFPGRMG K
Sbjct: 345 ELYDGQSLKQIFEDAGC-TIALPSCAACLGGPADTVGRSVDNDVVVSTTNRNFPGRMGSK 403
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
+YLASP TAAASA+TG++ DPR+FL
Sbjct: 404 HAGVYLASPLTAAASAITGKLTDPRDFL 431
[33][TOP]
>UniRef100_B3EHN8 Homoaconitate hydratase family protein n=1 Tax=Chlorobium limicola
DSM 245 RepID=B3EHN8_CHLL2
Length = 431
Score = 152 bits (384), Expect = 2e-35
Identities = 85/148 (57%), Positives = 99/148 (66%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
R + KI + YIGSCTGGK DFM AAK+ G++V VPT +V AT V AL
Sbjct: 290 RSMQGTKITKSYIGSCTGGKLTDFMLAAKILK--GKQVTVPTNIVPATVLV---ARALEC 344
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
G T +IFE+AGC A PSC ACLGGPADT R + V VSTTNRNFPGRMG K
Sbjct: 345 ETWEGVTLKKIFEDAGCSI-ALPSCAACLGGPADTVGRSADQDVVVSTTNRNFPGRMGSK 403
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
+ +YLASP TAAASA+TG++ DPREFL
Sbjct: 404 KADVYLASPLTAAASAVTGKLTDPREFL 431
[34][TOP]
>UniRef100_Q3APC5 3-isopropylmalate dehydratase n=1 Tax=Chlorobium chlorochromatii
CaD3 RepID=Q3APC5_CHLCH
Length = 431
Score = 151 bits (382), Expect = 4e-35
Identities = 84/148 (56%), Positives = 98/148 (66%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
R KI + YIGSCTGGK DFM AAK+ G+KV V T +V AT V +L
Sbjct: 290 RSVAGTKITKSYIGSCTGGKLSDFMMAAKILK--GQKVTVTTTIVPATTLV---ARSLET 344
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
GK+ QIFEEAGC+ A PSC ACLGGPADT R + + VSTTNRNFPGRMG K
Sbjct: 345 EQYDGKSLKQIFEEAGCNV-ALPSCAACLGGPADTVGRSVDNDLVVSTTNRNFPGRMGSK 403
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
+YLASP TAAASA+TG++ DPR+FL
Sbjct: 404 HAGVYLASPLTAAASAITGKLTDPRDFL 431
[35][TOP]
>UniRef100_A4SFC8 Homoaconitate hydratase family protein n=1 Tax=Chlorobium
phaeovibrioides DSM 265 RepID=A4SFC8_PROVI
Length = 431
Score = 151 bits (382), Expect = 4e-35
Identities = 82/145 (56%), Positives = 98/145 (67%)
Frame = -3
Query: 615 KDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGA 436
K KI + YIGSCTGGK DF AAK+ +G++V VPT +V AT KV D L
Sbjct: 293 KGTKITKSYIGSCTGGKLADFKLAAKIL--SGKRVSVPTNIVPATVKVAHD---LETELY 347
Query: 435 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 256
GK+ IFE+AGC A PSC ACLGGP DT R + V VSTTNRNFPGRMG K+ +
Sbjct: 348 NGKSLKSIFEDAGCSI-ALPSCAACLGGPTDTVGRSVDRDVVVSTTNRNFPGRMGSKQAE 406
Query: 255 IYLASPYTAAASALTGRVADPREFL 181
+YLASP TAAASA+TG++ DPR +L
Sbjct: 407 VYLASPLTAAASAITGKLTDPRNYL 431
[36][TOP]
>UniRef100_B4S6N0 Homoaconitate hydratase family protein n=1 Tax=Prosthecochloris
aestuarii DSM 271 RepID=B4S6N0_PROA2
Length = 432
Score = 149 bits (376), Expect = 2e-34
Identities = 79/148 (53%), Positives = 101/148 (68%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
R + +I + YIGSCTGGK DF AAK+ + G++V + T +V AT +V +L
Sbjct: 290 RSVQGTRITKSYIGSCTGGKLSDFKMAAKILN--GQQVSIQTNIVPATVEV---AKSLET 344
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
GK+ ++ E+AGC T A PSC ACLGGPADT+ R + + VSTTNRNFPGRMG K
Sbjct: 345 EQYEGKSIRKVLEDAGC-TIAQPSCAACLGGPADTFGRSEDNDLVVSTTNRNFPGRMGSK 403
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
+ +YLASP TAAASA+TGR+ DPREFL
Sbjct: 404 KAGVYLASPLTAAASAITGRLTDPREFL 431
[37][TOP]
>UniRef100_Q3B597 3-isopropylmalate dehydratase n=1 Tax=Chlorobium luteolum DSM 273
RepID=Q3B597_PELLD
Length = 431
Score = 147 bits (372), Expect = 5e-34
Identities = 82/148 (55%), Positives = 98/148 (66%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
R I + YIGSCTGGK DF AA++ + GRKV V T +V AT +V D L
Sbjct: 290 RSVAGTPITKSYIGSCTGGKLTDFKMAARILN--GRKVAVTTNIVPATVQVARD---LEQ 344
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
GKT QIF EAGC+ A PSC ACLGGPADT R + + VSTTNRNFPGRMG K
Sbjct: 345 EMHEGKTLKQIFMEAGCNI-ALPSCAACLGGPADTVGRSVDRDIVVSTTNRNFPGRMGSK 403
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
++YLASP TAAASA+TG++ DPR+F+
Sbjct: 404 NAEVYLASPLTAAASAITGKLTDPRDFI 431
[38][TOP]
>UniRef100_Q0YQD5 Homoaconitate hydratase family protein:3-isopropylmalate
dehydratase, prokaryotic n=1 Tax=Chlorobium ferrooxidans
DSM 13031 RepID=Q0YQD5_9CHLB
Length = 431
Score = 146 bits (369), Expect = 1e-33
Identities = 82/148 (55%), Positives = 97/148 (65%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
R + KI + YIGSCTGGK DF+ AAK+ G+KV V T +V AT V AL
Sbjct: 290 RSVQGTKITKSYIGSCTGGKLTDFVMAAKILK--GKKVSVTTNIVPATVLV---ARALET 344
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
G T QIFE+AGC A PSC ACLGGP+DT R + + VSTTNRNFPGRMG K
Sbjct: 345 ERFEGVTLKQIFEDAGCSI-ALPSCAACLGGPSDTVGRSVDNDLVVSTTNRNFPGRMGSK 403
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
+YLASP TAAASA+TG++ DPR+FL
Sbjct: 404 HAGVYLASPLTAAASAVTGKLTDPRDFL 431
[39][TOP]
>UniRef100_C1ZRL8 Homoaconitate hydratase family protein/3-isopropylmalate
dehydratase, large subunit n=1 Tax=Rhodothermus marinus
DSM 4252 RepID=C1ZRL8_RHOMR
Length = 432
Score = 145 bits (367), Expect = 2e-33
Identities = 76/147 (51%), Positives = 97/147 (65%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E K+DR YIGSCTGGK EDF+AAA++ G++V++ TF+V A+ V ++ +
Sbjct: 291 EVAGTKLDRAYIGSCTGGKLEDFIAAARILK--GQEVRIDTFVVPASTYVEQQLHHYKID 348
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
G + IF AGC SCGACLGGP DT+ R + +V +STTNRNFPGRMG K+
Sbjct: 349 GV---SLYDIFVNAGCKI-GHASCGACLGGPPDTFGRTHGTEVVISTTNRNFPGRMGSKQ 404
Query: 261 GQIYLASPYTAAASALTGRVADPREFL 181
+YLASP T AASALTG + DPRE L
Sbjct: 405 ASVYLASPLTVAASALTGVITDPREVL 431
[40][TOP]
>UniRef100_A6DRT0 3-isopropylmalate dehydratase n=1 Tax=Lentisphaera araneosa
HTCC2155 RepID=A6DRT0_9BACT
Length = 433
Score = 142 bits (358), Expect = 2e-32
Identities = 76/148 (51%), Positives = 96/148 (64%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + R YIGSCTGGKTEDF AAA++ + G+KV + TF+V +T V D+ L
Sbjct: 291 EIAGTDLTRAYIGSCTGGKTEDFAAAAEIMY--GQKVAMDTFVVPSTTFVEKDLNTLKFK 348
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
KT +IF EAGC P C ACLGGP DT+ R + ++ VSTTNRNFPGRMG +
Sbjct: 349 D---KTYMEIFLEAGCRI-GPPGCAACLGGPEDTFGRTHAEEIVVSTTNRNFPGRMGSMQ 404
Query: 261 GQIYLASPYTAAASALTGRVADPREFLQ 178
++YLASPY AAASALTG + P +L+
Sbjct: 405 AKVYLASPYVAAASALTGVITKPDSYLE 432
[41][TOP]
>UniRef100_Q8KER8 3-isopropylmalate dehydratase, large subunit, putative n=1
Tax=Chlorobaculum tepidum RepID=Q8KER8_CHLTE
Length = 431
Score = 142 bits (357), Expect = 3e-32
Identities = 80/141 (56%), Positives = 93/141 (65%)
Frame = -3
Query: 603 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGGKT 424
I + YIGSCTGGK DF AAK+ G+KV V T +V AT V L G+T
Sbjct: 297 ITKSYIGSCTGGKLTDFKLAAKILK--GKKVAVTTNIVPATVLV---ASQLETEMYDGQT 351
Query: 423 CAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYLA 244
IFEEAGC+ A PSC ACLGGP+DT R + V VSTTNRNFPGRMG K +YLA
Sbjct: 352 LRHIFEEAGCNI-ALPSCAACLGGPSDTVGRSVDNDVVVSTTNRNFPGRMGSKFASVYLA 410
Query: 243 SPYTAAASALTGRVADPREFL 181
SP TAAASA+TG++ DPR+FL
Sbjct: 411 SPLTAAASAITGKLTDPRDFL 431
[42][TOP]
>UniRef100_B3EKV4 Homoaconitate hydratase family protein n=1 Tax=Chlorobium
phaeobacteroides BS1 RepID=B3EKV4_CHLPB
Length = 432
Score = 142 bits (357), Expect = 3e-32
Identities = 79/149 (53%), Positives = 98/149 (65%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
R + KI + YIGSCTGGK DF+ AAK+ G V VPT +V AT +V +L
Sbjct: 290 RSVQGTKITKSYIGSCTGGKLIDFVMAAKVLK--GNTVSVPTNIVPATVEV---AQSLTT 344
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
G+ I +EAGC T A PSC ACLGGP+DT+ R + + VSTTNRNFPGRMG K
Sbjct: 345 EEFDGQPIITILKEAGC-TIAPPSCAACLGGPSDTFGRSVDNDLVVSTTNRNFPGRMGSK 403
Query: 264 EGQIYLASPYTAAASALTGRVADPREFLQ 178
+ + LASP TAAASA+TG++ DPREFL+
Sbjct: 404 KAGVCLASPLTAAASAITGKLTDPREFLR 432
[43][TOP]
>UniRef100_B3QM97 Homoaconitate hydratase family protein n=1 Tax=Chlorobaculum parvum
NCIB 8327 RepID=B3QM97_CHLP8
Length = 431
Score = 140 bits (353), Expect = 9e-32
Identities = 81/148 (54%), Positives = 94/148 (63%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
R I + YIGSCTGGK DF AAK+ G+KV V T +V AT V L
Sbjct: 290 RSVAGTPITKSYIGSCTGGKITDFRLAAKILK--GKKVAVTTNIVPATVLV---ASQLEN 344
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
G+T IFEEAGC+ A PSC ACLGGP+DT R + V VSTTNRNFPGRMG K
Sbjct: 345 EMYDGQTLRHIFEEAGCNI-ALPSCAACLGGPSDTVGRSVDNDVVVSTTNRNFPGRMGSK 403
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
+YLASP TAAASA+TG++ DPR+FL
Sbjct: 404 MAGVYLASPLTAAASAVTGKLTDPRDFL 431
[44][TOP]
>UniRef100_B3QSN7 Homoaconitate hydratase family protein n=1 Tax=Chloroherpeton
thalassium ATCC 35110 RepID=B3QSN7_CHLT3
Length = 431
Score = 140 bits (352), Expect = 1e-31
Identities = 74/148 (50%), Positives = 95/148 (64%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
R K+ + Y+GSCTGGK DF AAK+ H G+ VKVPTF+V + V + +
Sbjct: 290 RNVAGTKLTKCYLGSCTGGKLTDFEFAAKVLH--GQTVKVPTFVVPGSTLVAKQLTEKTI 347
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
G T +IFE+AGC A SC ACLGGPADT R ++ +STTNRNFPGRMG K
Sbjct: 348 DGM---TYMEIFEKAGCII-AESSCAACLGGPADTVGRSSDGDTVISTTNRNFPGRMGSK 403
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
+ ++YLASP T AASA+ G + DPR+F+
Sbjct: 404 KSEVYLASPLTVAASAVNGVITDPRDFV 431
[45][TOP]
>UniRef100_B2VKF3 3-isopropylmalate dehydratase large subunit n=1 Tax=Erwinia
tasmaniensis RepID=B2VKF3_ERWT9
Length = 436
Score = 140 bits (352), Expect = 1e-31
Identities = 71/141 (50%), Positives = 94/141 (66%)
Frame = -3
Query: 615 KDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGA 436
K+V I + YIGSCTGGK DF+AAA++ GRKV VPTF V AT++V+ + + + G
Sbjct: 293 KNVAISQAYIGSCTGGKLADFIAAARVIK--GRKVVVPTFAVPATKEVFHGLISTDIDG- 349
Query: 435 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 256
++ +I +AG + C AC GGPADT+ R+N+P +STTNRNF GRMGHK
Sbjct: 350 --QSVYRILCDAGVQLSSESGCAACCGGPADTFGRVNQPISVISTTNRNFVGRMGHKRAN 407
Query: 255 IYLASPYTAAASALTGRVADP 193
IYLASPY AA+A+TG + P
Sbjct: 408 IYLASPYAVAAAAVTGEITHP 428
[46][TOP]
>UniRef100_Q6B920 3-isopropylmalate dehydratase large subunit n=1 Tax=Gracilaria
tenuistipitata var. liui RepID=Q6B920_GRATL
Length = 439
Score = 134 bits (336), Expect = 8e-30
Identities = 68/143 (47%), Positives = 89/143 (62%)
Frame = -3
Query: 606 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGGK 427
KIDR YIGSCTGGK+ DF AAAK+ KV + TF V AT++V+ D+ +
Sbjct: 301 KIDRAYIGSCTGGKSSDFYAAAKILK--NHKVSIDTFGVPATREVFYDIINQKIDDI--- 355
Query: 426 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 247
+ +I AG PSC AC GGP DT+ R+N +STTNRNF GRMG K QIYL
Sbjct: 356 SVYEILVNAGVHMTTEPSCAACCGGPIDTFGRVNNTMSVISTTNRNFSGRMGAKSAQIYL 415
Query: 246 ASPYTAAASALTGRVADPREFLQ 178
SPY+ A++A+ G + +P+ FL+
Sbjct: 416 GSPYSVASTAIAGHITNPKIFLK 438
[47][TOP]
>UniRef100_A0RXN9 3-isopropylmalate dehydratase large subunit n=1 Tax=Cenarchaeum
symbiosum RepID=A0RXN9_CENSY
Length = 429
Score = 118 bits (296), Expect = 4e-25
Identities = 67/146 (45%), Positives = 88/146 (60%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RE V++D+ YIGSCTG K ED AAA++ GRKV++ T ++ A ++ +
Sbjct: 296 REAPSVELDKAYIGSCTGAKMEDLEAAARILK--GRKVRIRTEVLPAAISIYRKAVERGL 353
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
G IF +AG T P+CGAC G L + +VC+STTNRNFPGRMG
Sbjct: 354 VG--------IFLDAGA-TVGPPTCGACCGAHMGV---LGKGEVCISTTNRNFPGRMGDI 401
Query: 264 EGQIYLASPYTAAASALTGRVADPRE 187
E Q YLASP AAASA+TG++ DPR+
Sbjct: 402 ESQTYLASPLVAAASAVTGKITDPRD 427
[48][TOP]
>UniRef100_A9A5B7 3-isopropylmalate dehydratase n=1 Tax=Nitrosopumilus maritimus SCM1
RepID=A9A5B7_NITMS
Length = 422
Score = 115 bits (288), Expect = 3e-24
Identities = 65/146 (44%), Positives = 88/146 (60%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RE V++D+ YIGSCTG K ED AAAK+ G+ VK+ T ++ A+ ++
Sbjct: 290 REAPSVELDKSYIGSCTGAKYEDLEAAAKILK--GKTVKIRTEILPASISIYKR------ 341
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
A IF +AG T P+CGAC G A+ ++C+STTNRNFPGRMGH
Sbjct: 342 --AMENGLLTIFLDAGV-TVGPPTCGACCGAHMGVLAK---NEICISTTNRNFPGRMGHV 395
Query: 264 EGQIYLASPYTAAASALTGRVADPRE 187
E + YL+SP AAASA+TG++ DPR+
Sbjct: 396 ESETYLSSPMVAAASAVTGKITDPRD 421
[49][TOP]
>UniRef100_B3TBB7 Putative aconitase family (Aconitate hydratase) n=1 Tax=uncultured
marine crenarchaeote HF4000_APKG8O8 RepID=B3TBB7_9ARCH
Length = 423
Score = 115 bits (288), Expect = 3e-24
Identities = 67/146 (45%), Positives = 88/146 (60%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
+E ++ID+ YIGSCTG K ED +A A++ GRKVKV T +V A ++
Sbjct: 291 QETTGIEIDKSYIGSCTGAKYEDLVAVARILK--GRKVKVRTEVVPAAISIYKK------ 342
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
A +IF +AG A P+CGAC G A+ +VCVSTTNRNFPGRMGH
Sbjct: 343 --ASENGLDKIFLDAGAVIGA-PTCGACCGAHMGVLAK---DEVCVSTTNRNFPGRMGHV 396
Query: 264 EGQIYLASPYTAAASALTGRVADPRE 187
+ + YL SP AAASA+TG++ DPR+
Sbjct: 397 DSKTYLTSPLVAAASAVTGKLTDPRD 422
[50][TOP]
>UniRef100_B3TAM8 Putative aconitase family (Aconitate hydratase) n=1 Tax=uncultured
marine crenarchaeote HF4000_APKG8G2 RepID=B3TAM8_9ARCH
Length = 423
Score = 114 bits (286), Expect = 5e-24
Identities = 65/146 (44%), Positives = 86/146 (58%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
+E +++D+ YIGSCTG K ED A AK+ G+KVK+ T ++ A ++
Sbjct: 291 QETTGIELDKSYIGSCTGAKYEDLEAVAKILK--GKKVKIRTEILPAAISIYKK------ 342
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
A QIF +AG P+CGAC G A+ +VCVSTTNRNFPGRMGH
Sbjct: 343 --ATENGLTQIFIDAGA-VVGPPTCGACCGAHMGVLAK---DEVCVSTTNRNFPGRMGHV 396
Query: 264 EGQIYLASPYTAAASALTGRVADPRE 187
E + YL SP AAASA+TG++ DPR+
Sbjct: 397 ESKTYLTSPLVAAASAVTGKLTDPRD 422
[51][TOP]
>UniRef100_B3T9D1 Putative aconitase family (Aconitate hydratase) n=1 Tax=uncultured
marine crenarchaeote HF4000_APKG6J21 RepID=B3T9D1_9ARCH
Length = 423
Score = 114 bits (286), Expect = 5e-24
Identities = 65/146 (44%), Positives = 86/146 (58%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
+E +++D+ YIGSCTG K ED A AK+ G+KVK+ T ++ A ++
Sbjct: 291 QETTGIELDKSYIGSCTGAKYEDLEAVAKILK--GKKVKIRTEILPAAISIYKK------ 342
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
A QIF +AG P+CGAC G A+ +VCVSTTNRNFPGRMGH
Sbjct: 343 --ATENGLTQIFIDAGA-VVGPPTCGACCGAHMGVLAK---DEVCVSTTNRNFPGRMGHV 396
Query: 264 EGQIYLASPYTAAASALTGRVADPRE 187
E + YL SP AAASA+TG++ DPR+
Sbjct: 397 ESKTYLTSPLVAAASAVTGKLTDPRD 422
[52][TOP]
>UniRef100_B3T8D2 Putative aconitase family (Aconitate hydratase) n=1 Tax=uncultured
marine crenarchaeote HF4000_APKG5E24 RepID=B3T8D2_9ARCH
Length = 423
Score = 114 bits (286), Expect = 5e-24
Identities = 65/146 (44%), Positives = 86/146 (58%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
+E +++D+ YIGSCTG K ED A AK+ G+KVK+ T ++ A ++
Sbjct: 291 QETTGIELDKSYIGSCTGAKYEDLEAVAKILK--GKKVKIRTEILPAAISIYKK------ 342
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
A QIF +AG P+CGAC G A+ +VCVSTTNRNFPGRMGH
Sbjct: 343 --ATENGLTQIFIDAGA-VVGPPTCGACCGAHMGVLAK---DEVCVSTTNRNFPGRMGHV 396
Query: 264 EGQIYLASPYTAAASALTGRVADPRE 187
E + YL SP AAASA+TG++ DPR+
Sbjct: 397 ESKTYLTSPLVAAASAVTGKLTDPRD 422
[53][TOP]
>UniRef100_UPI0001966B48 hypothetical protein SUBVAR_01587 n=1 Tax=Subdoligranulum variabile
DSM 15176 RepID=UPI0001966B48
Length = 419
Score = 113 bits (283), Expect = 1e-23
Identities = 64/146 (43%), Positives = 86/146 (58%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
+E KD+KID++ IGSCT G+ ED AA ++ V ++ AT V+ +
Sbjct: 285 KEGKDIKIDQIVIGSCTNGRIEDMQAAYEILKGKHIAKGVRGIIIPATMAVYKECIL--- 341
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
+ + F +AGC ++P+CG CLGG A + CVSTTNRNF GRMGH
Sbjct: 342 -----RGYTEAFIDAGCIV-STPTCGPCLGGYMGILAA---GERCVSTTNRNFVGRMGHV 392
Query: 264 EGQIYLASPYTAAASALTGRVADPRE 187
+ ++YLASP TAAASALTG + DPRE
Sbjct: 393 DSEVYLASPATAAASALTGYITDPRE 418
[54][TOP]
>UniRef100_C0EDN6 Putative uncharacterized protein n=1 Tax=Clostridium methylpentosum
DSM 5476 RepID=C0EDN6_9CLOT
Length = 421
Score = 112 bits (281), Expect = 2e-23
Identities = 63/147 (42%), Positives = 85/147 (57%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E DVKID+V IGSCT G+ D AAK+ V ++ ATQK++++ L
Sbjct: 286 EVGDVKIDQVVIGSCTNGRLSDIAVAAKILEGKQVAKHVRAIVIPATQKIYLEALKLGY- 344
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
+ F +AGC ++P+CG CLGG A + VSTTNRNF GRMGH E
Sbjct: 345 -------LETFVKAGC-VVSTPTCGPCLGGHMGILAA---GERAVSTTNRNFVGRMGHVE 393
Query: 261 GQIYLASPYTAAASALTGRVADPREFL 181
++YLASP AAASA+TG+++ P E +
Sbjct: 394 SEVYLASPEVAAASAVTGKISSPEEIM 420
[55][TOP]
>UniRef100_C4ZBK5 3-isopropylmalate dehydratase, large subunit n=1 Tax=Eubacterium
rectale ATCC 33656 RepID=C4ZBK5_EUBR3
Length = 420
Score = 112 bits (279), Expect = 3e-23
Identities = 65/149 (43%), Positives = 92/149 (61%), Gaps = 2/149 (1%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALP 448
E DVKID+V IGSCT G+ +D AAK+ G+KV + ++ ATQK+++
Sbjct: 286 EVGDVKIDQVVIGSCTNGRMDDLRIAAKILE--GKKVADGIRVIVIPATQKIYLQ----- 338
Query: 447 VPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
A + + F EAG ++P+CG CLGG A E + CVSTTNRNF GRMGH
Sbjct: 339 ---AMEEGLLKTFIEAGAIV-STPTCGPCLGGYMGVLA---EGERCVSTTNRNFVGRMGH 391
Query: 267 KEGQIYLASPYTAAASALTGRVADPREFL 181
+ ++YLASP AAASA+TG+++ P++ +
Sbjct: 392 VDSEVYLASPAVAAASAITGKISGPKDVM 420
[56][TOP]
>UniRef100_Q3ZZK0 Homoaconitate hydratase family protein n=1 Tax=Dehalococcoides sp.
CBDB1 RepID=Q3ZZK0_DEHSC
Length = 417
Score = 111 bits (278), Expect = 4e-23
Identities = 62/148 (41%), Positives = 87/148 (58%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RE K K+D+V+IG+CTGG+ +D AA +F R + + A+QK++++ L
Sbjct: 282 RELKGTKLDQVFIGTCTGGRLDDLAVAAAIFKNRKRHPQTRLIVTPASQKIYLEAIRLGY 341
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
+I +AG + P CGACLG L + +VC+ST NRNF GRMG+
Sbjct: 342 --------IEILVQAGANI-MPPGCGACLGVHQGV---LGDGEVCLSTANRNFKGRMGNP 389
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
EG IYLAS TAAASA+ G ++DPRE +
Sbjct: 390 EGFIYLASAATAAASAIKGEISDPREVM 417
[57][TOP]
>UniRef100_A5FS15 3-isopropylmalate dehydratase, large subunit n=1
Tax=Dehalococcoides sp. BAV1 RepID=A5FS15_DEHSB
Length = 431
Score = 111 bits (278), Expect = 4e-23
Identities = 62/148 (41%), Positives = 87/148 (58%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RE K K+D+V+IG+CTGG+ +D AA +F R + + A+QK++++ L
Sbjct: 296 RELKGTKLDQVFIGTCTGGRLDDLAVAAAIFKNRKRHPQTRLIVTPASQKIYLEAIRLGY 355
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
+I +AG + P CGACLG L + +VC+ST NRNF GRMG+
Sbjct: 356 --------IEILVQAGANI-MPPGCGACLGVHQGV---LGDGEVCLSTANRNFKGRMGNP 403
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
EG IYLAS TAAASA+ G ++DPRE +
Sbjct: 404 EGFIYLASAATAAASAIKGEISDPREVM 431
[58][TOP]
>UniRef100_C7GFH7 3-isopropylmalate dehydratase, large subunit n=1 Tax=Roseburia
intestinalis L1-82 RepID=C7GFH7_9FIRM
Length = 420
Score = 111 bits (277), Expect = 6e-23
Identities = 67/147 (45%), Positives = 90/147 (61%), Gaps = 2/147 (1%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALP 448
E D+KID+V IGSCT G+ +D AA + G+KV + ++ ATQK+++D
Sbjct: 286 EVGDIKIDQVVIGSCTNGRMDDLRVAASILK--GKKVAKGLRVIVIPATQKIYLD----- 338
Query: 447 VPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
A + + F EAG ++P+CG CLGG A E + CVSTTNRNF GRMGH
Sbjct: 339 ---AMEEGLLKTFIEAGA-VVSTPTCGPCLGGYMGILA---EHERCVSTTNRNFVGRMGH 391
Query: 267 KEGQIYLASPYTAAASALTGRVADPRE 187
E +IYLASP AAASA+TG+++ P E
Sbjct: 392 VESEIYLASPAVAAASAITGKLSGPDE 418
[59][TOP]
>UniRef100_C4FRW1 Putative uncharacterized protein n=1 Tax=Veillonella dispar ATCC
17748 RepID=C4FRW1_9FIRM
Length = 419
Score = 111 bits (277), Expect = 6e-23
Identities = 69/145 (47%), Positives = 89/145 (61%), Gaps = 2/145 (1%)
Frame = -3
Query: 615 KDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVP 442
KD+KID+V IGSCT G+ ED +AAA++F GRKV V ++ +Q DVY +
Sbjct: 288 KDIKIDQVIIGSCTNGRYEDLVAAAEIFK--GRKVAPFVRCIVIPGSQ----DVYDQAMK 341
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
IF +A C ++P+CG CLGG A E + VSTTNRNF GRMGH +
Sbjct: 342 DG----LLDIFIQADCAV-STPTCGPCLGGYMGIMA---EGERTVSTTNRNFRGRMGHVD 393
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
++YLASPY AAASA+ GR+A P E
Sbjct: 394 SEVYLASPYVAAASAVLGRIAGPEE 418
[60][TOP]
>UniRef100_C0V4R3 3-isopropylmalate dehydratase, large subunit n=1 Tax=Veillonella
parvula DSM 2008 RepID=C0V4R3_9FIRM
Length = 419
Score = 111 bits (277), Expect = 6e-23
Identities = 69/145 (47%), Positives = 89/145 (61%), Gaps = 2/145 (1%)
Frame = -3
Query: 615 KDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVP 442
KD+KID+V IGSCT G+ ED +AAA++F GRKV V ++ +Q DVY +
Sbjct: 288 KDIKIDQVIIGSCTNGRYEDLVAAAEIFK--GRKVAPFVRCIVIPGSQ----DVYDQAMK 341
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
IF +A C ++P+CG CLGG A E + VSTTNRNF GRMGH +
Sbjct: 342 DG----LLDIFIQADCAV-STPTCGPCLGGYMGIMA---EGERTVSTTNRNFRGRMGHVD 393
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
++YLASPY AAASA+ GR+A P E
Sbjct: 394 SEVYLASPYVAAASAVLGRIAGPEE 418
[61][TOP]
>UniRef100_C7H4B6 3-isopropylmalate dehydratase, large subunit n=1
Tax=Faecalibacterium prausnitzii A2-165
RepID=C7H4B6_9FIRM
Length = 419
Score = 110 bits (276), Expect = 7e-23
Identities = 64/144 (44%), Positives = 84/144 (58%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E KD++ID+V IGSCT G+ ED AA + V ++ AT V+ +
Sbjct: 286 EGKDIRIDQVVIGSCTNGRLEDMEAAYNILKGKHIAKGVRGIIIPATMAVYKECIL---- 341
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
+ + F +AGC ++P+CG CLGG A E + CVSTTNRNF GRMGH +
Sbjct: 342 ----RGWTEAFIDAGCIV-STPTCGPCLGGYMGILA---EGERCVSTTNRNFVGRMGHVK 393
Query: 261 GQIYLASPYTAAASALTGRVADPR 190
++YLASP TAAASALTG + DPR
Sbjct: 394 SEVYLASPATAAASALTGYITDPR 417
[62][TOP]
>UniRef100_Q3Z9A7 Homoaconitate hydratase family protein n=1 Tax=Dehalococcoides
ethenogenes 195 RepID=Q3Z9A7_DEHE1
Length = 417
Score = 110 bits (275), Expect = 1e-22
Identities = 62/148 (41%), Positives = 86/148 (58%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RE K K+D+V+IG+CTGG+ +D AA +F + + A+QKV+++ L
Sbjct: 282 RELKGTKLDQVFIGTCTGGRLDDLAVAAAIFKNRRHHPQTRLIVTPASQKVYLEAIRLGY 341
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
+I +AG + P CGACLG L + +VC+ST NRNF GRMG+
Sbjct: 342 --------IEILVQAGANV-MPPGCGACLGVHQGV---LGDGEVCLSTANRNFKGRMGNP 389
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
EG IYLAS TAAASA+ G ++DPRE +
Sbjct: 390 EGFIYLASAATAAASAIKGEISDPREVM 417
[63][TOP]
>UniRef100_C3WDK0 Homoaconitate hydratase n=1 Tax=Fusobacterium mortiferum ATCC 9817
RepID=C3WDK0_FUSMR
Length = 424
Score = 110 bits (274), Expect = 1e-22
Identities = 67/151 (44%), Positives = 90/151 (59%), Gaps = 7/151 (4%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVPGA 436
VKID+ YIGSCTGG+ D AA + GRK+ V + A+++VW
Sbjct: 291 VKIDQAYIGSCTGGRYNDLKLAADILK--GRKIAEGVRLLISPASKEVW----------- 337
Query: 435 GGKTCA-----QIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMG 271
+ CA Q EAG AS SCGACLG + + E +VC+S+TNRNF GRMG
Sbjct: 338 --ERCAKDGILQTLSEAGATVLAS-SCGACLGIHSGA---IGEGEVCISSTNRNFIGRMG 391
Query: 270 HKEGQIYLASPYTAAASALTGRVADPREFLQ 178
K+G++YLASP + AA+ALTG + DPR+F++
Sbjct: 392 SKKGEVYLASPLSVAAAALTGYIVDPRKFIE 422
[64][TOP]
>UniRef100_A8CU07 Homoaconitate hydratase family protein n=1 Tax=Dehalococcoides sp.
VS RepID=A8CU07_9CHLR
Length = 417
Score = 110 bits (274), Expect = 1e-22
Identities = 62/148 (41%), Positives = 86/148 (58%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RE K K+D+V+IG+CTGG+ +D AA +F + + A+QKV+++ L
Sbjct: 282 RELKGTKLDQVFIGTCTGGRLDDLAVAAAIFKNRRHHPQTRLIVTPASQKVYLEAIRLGY 341
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
+I +AG + P CGACLG L + +VC+ST NRNF GRMG+
Sbjct: 342 --------IEILVQAGANI-MPPGCGACLGVHQGV---LGDGEVCLSTANRNFKGRMGNP 389
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
EG IYLAS TAAASA+ G ++DPRE +
Sbjct: 390 EGFIYLASAATAAASAIKGEISDPREVM 417
[65][TOP]
>UniRef100_C7II84 3-isopropylmalate dehydratase, large subunit n=1 Tax=Clostridium
papyrosolvens DSM 2782 RepID=C7II84_9CLOT
Length = 419
Score = 109 bits (273), Expect = 2e-22
Identities = 62/142 (43%), Positives = 82/142 (57%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
D+KID+V IGSCT G+ ED AA++ V ++ ATQK+W A
Sbjct: 289 DIKIDQVVIGSCTNGRIEDMRIAAQILKGQKVSDNVRCIIIPATQKIWKQ--------AM 340
Query: 432 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
+ IF +AG ++P+CG CLGG A+ + V+TTNRNF GRMGH E ++
Sbjct: 341 NEGLFDIFIDAGAAV-STPTCGPCLGGHMGILAK---GERAVATTNRNFVGRMGHPESEV 396
Query: 252 YLASPYTAAASALTGRVADPRE 187
YLASP AAASA+ GR+A P E
Sbjct: 397 YLASPAVAAASAIAGRIAGPDE 418
[66][TOP]
>UniRef100_C6PQI2 3-isopropylmalate dehydratase, large subunit n=1 Tax=Clostridium
carboxidivorans P7 RepID=C6PQI2_9CLOT
Length = 421
Score = 109 bits (273), Expect = 2e-22
Identities = 61/145 (42%), Positives = 86/145 (59%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E +V ID+ IGSCT G+ ED AAAK+F +V + ATQK++++
Sbjct: 286 EVGEVFIDQAVIGSCTNGRIEDLRAAAKVFKGNKVNKRVRAIIFPATQKIYLEALR---- 341
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
+ +IF EAG ++P+CG CLGG A+ + ++TTNRNF GRMGH E
Sbjct: 342 ----EGLLEIFIEAGA-VVSTPTCGPCLGGHMGILAK---GERAIATTNRNFVGRMGHPE 393
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
++YLASP AAASA+TG+++ P E
Sbjct: 394 SEVYLASPAVAAASAITGKISSPEE 418
[67][TOP]
>UniRef100_C1QEQ6 3-isopropylmalate dehydratase large subunit n=1 Tax=Brachyspira
murdochii DSM 12563 RepID=C1QEQ6_9SPIR
Length = 201
Score = 109 bits (273), Expect = 2e-22
Identities = 62/145 (42%), Positives = 83/145 (57%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
+E KD+K+D+V IGSCT G+ D AA + V ++ ATQKV+ + L
Sbjct: 69 KELKDIKVDQVVIGSCTNGRLSDMATAANILKGKKIAKNVRCIIIPATQKVYKECIKLGY 128
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
IF +AGC ++P+CG CLGG A +V V+TTNRNF GRMG K
Sbjct: 129 --------MDIFIDAGCAV-STPTCGPCLGGYMGILAH---DEVAVTTTNRNFVGRMGDK 176
Query: 264 EGQIYLASPYTAAASALTGRVADPR 190
++YLASP TAA SALTG + +P+
Sbjct: 177 TSKVYLASPATAAYSALTGYITEPK 201
[68][TOP]
>UniRef100_A8S7H1 Putative uncharacterized protein n=1 Tax=Faecalibacterium
prausnitzii M21/2 RepID=A8S7H1_9FIRM
Length = 419
Score = 109 bits (273), Expect = 2e-22
Identities = 67/144 (46%), Positives = 84/144 (58%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E KD+KID+V IGSCT G+ ED AA + V ++ AT V+ +
Sbjct: 286 EGKDIKIDQVVIGSCTNGRLEDMEAAYNILKGKHIAKGVRGIIIPATMAVYKECILR--- 342
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
G T A F +AGC ++P+CG CLGG A + CVSTTNRNF GRMGH +
Sbjct: 343 ---GWTTA--FIDAGCIV-STPTCGPCLGGYMGILAA---GERCVSTTNRNFVGRMGHVD 393
Query: 261 GQIYLASPYTAAASALTGRVADPR 190
++YLASP TAAASALTG + DPR
Sbjct: 394 SEVYLASPATAAASALTGYITDPR 417
[69][TOP]
>UniRef100_C6LJ75 3-isopropylmalate dehydratase, large subunit n=1 Tax=Bryantella
formatexigens DSM 14469 RepID=C6LJ75_9FIRM
Length = 422
Score = 109 bits (272), Expect = 2e-22
Identities = 66/145 (45%), Positives = 88/145 (60%), Gaps = 2/145 (1%)
Frame = -3
Query: 615 KDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVP 442
+DV ID+ IGSCT G+ +D AAK+ GRKVK V ++ ATQKV++
Sbjct: 289 EDVVIDQAVIGSCTNGRIDDLRCAAKILE--GRKVKKGVRCIVIPATQKVYLQ------- 339
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
A + + F EAG ++P+CG CLGG A E + C+STTNRNF GRMGH
Sbjct: 340 -AMEEGLLKTFIEAGA-VVSTPTCGPCLGGYMGILA---EGERCISTTNRNFVGRMGHVN 394
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
++YLASP AAASA+TG+++ P E
Sbjct: 395 SEVYLASPAVAAASAVTGKISAPAE 419
[70][TOP]
>UniRef100_C4EWE6 3-isopropylmalate dehydratase, large subunit n=1
Tax=Thermanaerovibrio acidaminovorans DSM 6589
RepID=C4EWE6_9BACT
Length = 417
Score = 109 bits (272), Expect = 2e-22
Identities = 66/146 (45%), Positives = 84/146 (57%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RE +DV+I +V+IGSCT G+ ED AAK+ V L+ A+++ D+ A
Sbjct: 282 RELRDVEIHQVFIGSCTNGRIEDLRQAAKVLKGRRLHPSVRGVLIPASRR---DMAAAMQ 338
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
G ++F EAG +PSCG CLGG A E +VCVST NRNF GRMGH
Sbjct: 339 EGL-----MEVFMEAGFSI-CTPSCGPCLGGHLGILA---EGEVCVSTGNRNFTGRMGHP 389
Query: 264 EGQIYLASPYTAAASALTGRVADPRE 187
Q+YLASP AAAS + GR+ DP E
Sbjct: 390 RSQVYLASPAVAAASGVMGRIWDPSE 415
[71][TOP]
>UniRef100_C0FYL9 Putative uncharacterized protein n=1 Tax=Roseburia inulinivorans
DSM 16841 RepID=C0FYL9_9FIRM
Length = 436
Score = 109 bits (272), Expect = 2e-22
Identities = 65/149 (43%), Positives = 90/149 (60%), Gaps = 2/149 (1%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALP 448
E DVKID+V IGSCT G+ +D AA + G+KVK + ++ ATQK+++
Sbjct: 302 EVGDVKIDQVVIGSCTNGRMDDLRIAASVLK--GKKVKKGLRVIVIPATQKIYLQ----- 354
Query: 447 VPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
A + + F EAG ++P+CG CLGG A + CVSTTNRNF GRMGH
Sbjct: 355 ---AMEEGLLRTFIEAGA-VVSTPTCGPCLGGYMGILAA---GERCVSTTNRNFVGRMGH 407
Query: 267 KEGQIYLASPYTAAASALTGRVADPREFL 181
+ ++YLASP AAASA+TG+++ P E +
Sbjct: 408 VDSEVYLASPAVAAASAITGKISSPEEVM 436
[72][TOP]
>UniRef100_A8UWH6 3-isopropylmalate dehydratase n=1 Tax=Hydrogenivirga sp. 128-5-R1-1
RepID=A8UWH6_9AQUI
Length = 432
Score = 108 bits (271), Expect = 3e-22
Identities = 64/153 (41%), Positives = 89/153 (58%), Gaps = 5/153 (3%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAA---GRKVK--VPTFLVTATQKVWMDVY 457
E + +D+ +IGSCT G+ ED AAK+F +A G+KV V ++ A++ V+M
Sbjct: 285 ESTHINVDQAFIGSCTNGRIEDLRIAAKVFESALKQGKKVHPYVRCIVIPASKNVYMQ-- 342
Query: 456 ALPVPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGR 277
A + IF EAGC S +CG CLGG A E + C+ST+NRNFPGR
Sbjct: 343 ------AMKEGLIDIFMEAGCAVSTS-TCGPCLGGHMGVLA---EGERCISTSNRNFPGR 392
Query: 276 MGHKEGQIYLASPYTAAASALTGRVADPREFLQ 178
MGH + + YLA+P AASA+ GR+A P E ++
Sbjct: 393 MGHPKSESYLANPAVVAASAVLGRIAHPEEVVR 425
[73][TOP]
>UniRef100_A0B7A3 3-isopropylmalate dehydratase, large subunit n=1 Tax=Methanosaeta
thermophila PT RepID=A0B7A3_METTP
Length = 382
Score = 108 bits (271), Expect = 3e-22
Identities = 58/146 (39%), Positives = 92/146 (63%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
R+ +++D+V+IG+CT G+ ED AA++ G++VK+ T ++ A++++++
Sbjct: 251 RDLAGIEVDQVFIGTCTNGRLEDLEMAARI--VKGKRVKIRTLVIPASREIYL------- 301
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
GA + EAG P CG CLG L + +VC+ST+NRNFPGRMG +
Sbjct: 302 -GALRSGVIETLVEAGAMI-GPPGCGPCLGAHMGV---LGDGEVCLSTSNRNFPGRMG-R 355
Query: 264 EGQIYLASPYTAAASALTGRVADPRE 187
G++YLASP TAAA+A+TG++ DPR+
Sbjct: 356 NGKVYLASPATAAATAITGKITDPRD 381
[74][TOP]
>UniRef100_A6TTR7 3-isopropylmalate dehydratase, large subunit n=1 Tax=Alkaliphilus
metalliredigens QYMF RepID=A6TTR7_ALKMQ
Length = 420
Score = 107 bits (268), Expect = 6e-22
Identities = 60/147 (40%), Positives = 87/147 (59%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E DVKID+V IGSCT G+ +D AAK+ V + ATQK+++D
Sbjct: 286 EVGDVKIDQVVIGSCTNGRIQDLRMAAKVMEGKQVAKGVRVIVFPATQKIYLD------- 338
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
A + + F +AG ++P+CG CLGG A+ + ++TTNRNF GRMGH E
Sbjct: 339 -AMKEGLLETFIKAGA-VVSTPTCGPCLGGHMGVLAK---GERAIATTNRNFVGRMGHPE 393
Query: 261 GQIYLASPYTAAASALTGRVADPREFL 181
++YLASP AAASA+TG++ +P++ +
Sbjct: 394 SEVYLASPAVAAASAITGKITNPKDIV 420
[75][TOP]
>UniRef100_Q8TVF2 3-isopropylmalate dehydratase large subunit 1 n=1 Tax=Methanopyrus
kandleri RepID=LEUC1_METKA
Length = 418
Score = 107 bits (268), Expect = 6e-22
Identities = 60/147 (40%), Positives = 85/147 (57%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + + ID+V+IGSCT G+ ED AA++ V ++ A+++V+ V
Sbjct: 284 EVEGIAIDQVFIGSCTNGRYEDLKVAAEVLEGEEVHDDVRLIVIPASREVYHRTLKDGV- 342
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
++ EAG P+CG CLGG A E + CV+T+NRNFPGRMGH+E
Sbjct: 343 -------LEVLHEAGA-LICPPNCGPCLGGHMGVLA---EGERCVATSNRNFPGRMGHRE 391
Query: 261 GQIYLASPYTAAASALTGRVADPREFL 181
++YLASP TAAASA+ G + DPR +L
Sbjct: 392 SEVYLASPATAAASAIEGEITDPRPYL 418
[76][TOP]
>UniRef100_B8I4G0 3-isopropylmalate dehydratase, large subunit n=1 Tax=Clostridium
cellulolyticum H10 RepID=B8I4G0_CLOCE
Length = 419
Score = 107 bits (267), Expect = 8e-22
Identities = 65/144 (45%), Positives = 84/144 (58%), Gaps = 2/144 (1%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVPG 439
D+KID+V IGSCT G+ ED AA + GRKV V ++ ATQK+W
Sbjct: 289 DIKIDQVVIGSCTNGRIEDMRIAAGVLK--GRKVSDNVRCIIIPATQKIWKQ-------- 338
Query: 438 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 259
A + IF +AG ++P+CG CLGG A+ + V+TTNRNF GRMGH E
Sbjct: 339 AMNEGLFDIFIDAGAAV-STPTCGPCLGGHMGILAK---GERAVATTNRNFVGRMGHPES 394
Query: 258 QIYLASPYTAAASALTGRVADPRE 187
++YLA P AAASA+ GR+A P E
Sbjct: 395 EVYLAGPAVAAASAVAGRIAGPDE 418
[77][TOP]
>UniRef100_C0FIT9 Putative uncharacterized protein n=1 Tax=Clostridium sp. M62/1
RepID=C0FIT9_9CLOT
Length = 278
Score = 107 bits (267), Expect = 8e-22
Identities = 65/149 (43%), Positives = 88/149 (59%), Gaps = 2/149 (1%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALP 448
E DV ID+V IGSCT G+ ED AA++ GRKVK V ++ ATQ +++
Sbjct: 143 EAGDVAIDQVVIGSCTNGRLEDMRIAAEILK--GRKVKKGVRCIVIPATQAIYLQCIK-- 198
Query: 447 VPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
+ + F EAG ++P+CG CLGG A + CVSTTNRNF GRMGH
Sbjct: 199 ------EGLMETFIEAGA-VVSTPTCGPCLGGYMGILAA---GERCVSTTNRNFVGRMGH 248
Query: 267 KEGQIYLASPYTAAASALTGRVADPREFL 181
+ ++YLASP AAASA+TG+++ P E +
Sbjct: 249 VDSEVYLASPAVAAASAVTGKISSPCEIM 277
[78][TOP]
>UniRef100_C0CLF7 Putative uncharacterized protein n=1 Tax=Blautia hydrogenotrophica
DSM 10507 RepID=C0CLF7_9FIRM
Length = 422
Score = 107 bits (266), Expect = 1e-21
Identities = 64/144 (44%), Positives = 88/144 (61%), Gaps = 2/144 (1%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVPG 439
DV ID+ IGSCT G+ ED AA++ GRKVK + ++ ATQ +++
Sbjct: 290 DVVIDQSVIGSCTNGRMEDLRIAAEILK--GRKVKKGIRCIVIPATQAIYLQ-------- 339
Query: 438 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 259
A + +IF EAG ++P+CG CLGG A E + C+STTNRNF GRMGH +
Sbjct: 340 AMKEGLLEIFIEAGA-VVSTPTCGPCLGGYMGILA---EGERCISTTNRNFVGRMGHVDS 395
Query: 258 QIYLASPYTAAASALTGRVADPRE 187
++YLASP AAASA+TG+++ P E
Sbjct: 396 EVYLASPAVAAASAVTGKISAPAE 419
[79][TOP]
>UniRef100_B0PBC0 Putative uncharacterized protein n=1 Tax=Anaerotruncus colihominis
DSM 17241 RepID=B0PBC0_9FIRM
Length = 419
Score = 107 bits (266), Expect = 1e-21
Identities = 65/145 (44%), Positives = 89/145 (61%), Gaps = 2/145 (1%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALP 448
E DV+ID+V IGSCT G+ D AAA+L +G+KV V ++ TQ+++ +
Sbjct: 286 EAGDVRIDQVVIGSCTNGRIGDLAAAARLM--SGKKVADGVRCIVIPGTQQIYREAIH-- 341
Query: 447 VPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
AG F +AGC ++P+CG CLGG A E + CV+TTNRNF GRMGH
Sbjct: 342 ---AG---YIDTFLDAGCAV-STPTCGPCLGGYMGILA---EGERCVATTNRNFVGRMGH 391
Query: 267 KEGQIYLASPYTAAASALTGRVADP 193
+ ++YLASP AAASA+ G++ADP
Sbjct: 392 VKSEVYLASPAVAAASAIRGKIADP 416
[80][TOP]
>UniRef100_A3DHI4 3-isopropylmalate dehydratase large subunit n=3 Tax=Clostridium
thermocellum RepID=LEUC_CLOTH
Length = 419
Score = 107 bits (266), Expect = 1e-21
Identities = 65/144 (45%), Positives = 85/144 (59%), Gaps = 2/144 (1%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVPG 439
++KID+V IGSCT G+ ED AA++ GRKV V ++ ATQK+W
Sbjct: 289 NIKIDQVVIGSCTNGRIEDLRVAAEVLK--GRKVHKDVRCIIIPATQKIWKQ-------- 338
Query: 438 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 259
A + IF +AG ++P+CG CLGG A+ + V+TTNRNF GRMGH E
Sbjct: 339 AMNEGLFDIFIDAGAAV-STPTCGPCLGGHMGILAK---GERAVATTNRNFVGRMGHPES 394
Query: 258 QIYLASPYTAAASALTGRVADPRE 187
+IYLASP AAASA+ GR+ P E
Sbjct: 395 EIYLASPAVAAASAVLGRIGSPDE 418
[81][TOP]
>UniRef100_C6E531 Homoaconitate hydratase family protein n=1 Tax=Geobacter sp. M21
RepID=C6E531_GEOSM
Length = 427
Score = 106 bits (265), Expect = 1e-21
Identities = 65/148 (43%), Positives = 86/148 (58%), Gaps = 1/148 (0%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E ++D+VY+GSCT G+ ED AA++ V L AT +++ D A
Sbjct: 294 EMAGTQVDQVYLGSCTNGRLEDLRVAAQILKGKKIASHVRAILSPATPQIYKDAVA---- 349
Query: 441 GAGGKTCAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
+ QIF +AG C T +P+CGACLG A E +VC STTNRNF GRMG K
Sbjct: 350 ----EGLIQIFMDAGFCVT--NPTCGACLGMSNGVLA---EGEVCASTTNRNFMGRMG-K 399
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
G ++L SP TAAASA+ G++ADPR +L
Sbjct: 400 GGMVHLLSPATAAASAIEGKIADPRNYL 427
[82][TOP]
>UniRef100_Q0QLE2 2,3-dimethylmalate dehydratase large subunit n=1 Tax=Eubacterium
barkeri RepID=Q0QLE2_EUBBA
Length = 420
Score = 106 bits (265), Expect = 1e-21
Identities = 65/141 (46%), Positives = 83/141 (58%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGG 430
V ID+V IGSCT G+ ED AA + K V ++ AT K+++D AG
Sbjct: 291 VTIDQVVIGSCTNGRFEDLKRAADILRGKHVKKGVRMLVIPATHKIYLDAME-----AG- 344
Query: 429 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 250
+ F EAG T ++P+CG CLGG A E + CVSTTNRNF GRMGH + ++Y
Sbjct: 345 --YLREFIEAGA-TISTPTCGPCLGGYMGILA---EGERCVSTTNRNFVGRMGHVDSEVY 398
Query: 249 LASPYTAAASALTGRVADPRE 187
LASP AAASA+ GR+A P E
Sbjct: 399 LASPEVAAASAILGRIATPDE 419
[83][TOP]
>UniRef100_C4GAI7 Putative uncharacterized protein n=1 Tax=Shuttleworthia satelles
DSM 14600 RepID=C4GAI7_9FIRM
Length = 434
Score = 106 bits (265), Expect = 1e-21
Identities = 65/149 (43%), Positives = 91/149 (61%), Gaps = 2/149 (1%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKV--KVPTFLVTATQKVWMDVYALP 448
+ +D+ ID+V IGSCT G+ D AAA++ GRKV +V T ++ ATQ++++D
Sbjct: 300 QIEDIAIDQVVIGSCTNGRLSDLKAAAEILK--GRKVADRVRTIIIPATQQIYLDAMQ-- 355
Query: 447 VPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
AG + F EAG ++P+CG CLGG A + CVSTTNRNF GRMG
Sbjct: 356 ---AG---YLKTFIEAGA-VVSTPTCGPCLGGYMGILAA---GERCVSTTNRNFVGRMGD 405
Query: 267 KEGQIYLASPYTAAASALTGRVADPREFL 181
++YLASP AAASA+TGR++ P + +
Sbjct: 406 VTSEVYLASPAVAAASAVTGRISGPADLI 434
[84][TOP]
>UniRef100_B5EHU2 3-isopropylmalate dehydratase large subunit n=1 Tax=Geobacter
bemidjiensis Bem RepID=LEUC_GEOBB
Length = 427
Score = 106 bits (265), Expect = 1e-21
Identities = 65/148 (43%), Positives = 86/148 (58%), Gaps = 1/148 (0%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E ++D+VY+GSCT G+ ED AA++ V L AT +++ D A
Sbjct: 294 EMAGTQVDQVYLGSCTNGRLEDLRVAAQILKGKKIASHVRAILSPATPQIYKDAVA---- 349
Query: 441 GAGGKTCAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
+ QIF +AG C T +P+CGACLG A E +VC STTNRNF GRMG K
Sbjct: 350 ----EGLIQIFMDAGFCVT--NPTCGACLGMSNGVLA---EGEVCASTTNRNFMGRMG-K 399
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
G ++L SP TAAASA+ G++ADPR +L
Sbjct: 400 GGMVHLLSPATAAASAIEGKIADPRNYL 427
[85][TOP]
>UniRef100_C0R088 3-isopropylmalate dehydratase large subunit n=1 Tax=Brachyspira
hyodysenteriae WA1 RepID=C0R088_BRAHW
Length = 415
Score = 106 bits (264), Expect = 2e-21
Identities = 63/147 (42%), Positives = 87/147 (59%), Gaps = 2/147 (1%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYAL 451
+E K++K+D+V IGSCT G+ D AA + G+KV V ++ ATQKV+ + L
Sbjct: 283 KELKNIKVDQVVIGSCTNGRLSDMATAANILK--GKKVAKGVRCIVIPATQKVYKECIKL 340
Query: 450 PVPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMG 271
IF +AGC ++P+CG CLGG A +V V+TTNRNF GRMG
Sbjct: 341 GY--------MDIFIDAGCAV-STPTCGPCLGGYMGILAH---DEVAVTTTNRNFVGRMG 388
Query: 270 HKEGQIYLASPYTAAASALTGRVADPR 190
K ++YLASP TAA SA+TG + +P+
Sbjct: 389 DKTSKVYLASPATAAYSAITGYITEPK 415
[86][TOP]
>UniRef100_B9KB94 3-isopropylmalate dehydratase large subunit 2 n=1 Tax=Thermotoga
neapolitana DSM 4359 RepID=B9KB94_THENN
Length = 417
Score = 106 bits (264), Expect = 2e-21
Identities = 60/145 (41%), Positives = 83/145 (57%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + +KID+V IGSCT G+ ED AA++ V ++ +QKV+
Sbjct: 284 EKERIKIDQVVIGSCTNGRIEDLRLAAQILKGRTVSPNVRCIIIPGSQKVYKQALK---- 339
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
+ IF +AGC ++P+CG CLGG A E ++ VSTTNRNF GRMGH
Sbjct: 340 ----EGLIDIFLDAGCAV-STPTCGPCLGGHMGVLA---EGEIAVSTTNRNFVGRMGHPN 391
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
+++LASP AAASA+ G +ADPR+
Sbjct: 392 SKVFLASPAVAAASAVKGYIADPRK 416
[87][TOP]
>UniRef100_B9E370 Putative uncharacterized protein n=1 Tax=Clostridium kluyveri NBRC
12016 RepID=B9E370_CLOK1
Length = 426
Score = 106 bits (264), Expect = 2e-21
Identities = 64/147 (43%), Positives = 88/147 (59%), Gaps = 2/147 (1%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALP 448
E ++KID+V IGSCT G+ D AAK+ GRKV V T + ATQ +++
Sbjct: 292 EVGEIKIDQVVIGSCTNGRIGDLRVAAKVLK--GRKVNSNVRTIIFPATQSIYLQ----- 344
Query: 447 VPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
A + +IF E+G ++P+CG CLGG A+ + V+TTNRNF GRMGH
Sbjct: 345 ---AMKEGLLEIFIESGA-VVSTPTCGPCLGGHMGILAK---GERAVATTNRNFTGRMGH 397
Query: 267 KEGQIYLASPYTAAASALTGRVADPRE 187
E ++YLASP AAASA+TG+++ P E
Sbjct: 398 VESEVYLASPAVAAASAVTGKISSPEE 424
[88][TOP]
>UniRef100_A5MZ75 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
kluyveri DSM 555 RepID=LEUC_CLOK5
Length = 420
Score = 106 bits (264), Expect = 2e-21
Identities = 64/147 (43%), Positives = 88/147 (59%), Gaps = 2/147 (1%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALP 448
E ++KID+V IGSCT G+ D AAK+ GRKV V T + ATQ +++
Sbjct: 286 EVGEIKIDQVVIGSCTNGRIGDLRVAAKVLK--GRKVNSNVRTIIFPATQSIYLQ----- 338
Query: 447 VPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
A + +IF E+G ++P+CG CLGG A+ + V+TTNRNF GRMGH
Sbjct: 339 ---AMKEGLLEIFIESGA-VVSTPTCGPCLGGHMGILAK---GERAVATTNRNFTGRMGH 391
Query: 267 KEGQIYLASPYTAAASALTGRVADPRE 187
E ++YLASP AAASA+TG+++ P E
Sbjct: 392 VESEVYLASPAVAAASAVTGKISSPEE 418
[89][TOP]
>UniRef100_O67078 3-isopropylmalate dehydratase large subunit n=1 Tax=Aquifex
aeolicus RepID=LEUC_AQUAE
Length = 432
Score = 106 bits (264), Expect = 2e-21
Identities = 63/153 (41%), Positives = 87/153 (56%), Gaps = 5/153 (3%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAA---GRKVK--VPTFLVTATQKVWMDVY 457
E + ID+ +IGSCT G+ ED AAK+F AA G+KV V ++ A++ ++
Sbjct: 285 ESTHITIDQAFIGSCTNGRIEDLRVAAKVFEAALKQGKKVHPYVRCIVIPASKAIYKQAL 344
Query: 456 ALPVPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGR 277
+ IF EAGC S +CG CLGG A E + C+ST+NRNFPGR
Sbjct: 345 K--------EGLIDIFMEAGCVVSTS-TCGPCLGGHMGVLA---EGERCISTSNRNFPGR 392
Query: 276 MGHKEGQIYLASPYTAAASALTGRVADPREFLQ 178
MGH + + YLA+P AASA+ GR+A P E ++
Sbjct: 393 MGHPKSESYLANPAVVAASAIMGRIAHPDEVVK 425
[90][TOP]
>UniRef100_UPI000196B289 hypothetical protein CATMIT_00953 n=1 Tax=Catenibacterium mitsuokai
DSM 15897 RepID=UPI000196B289
Length = 425
Score = 105 bits (263), Expect = 2e-21
Identities = 65/144 (45%), Positives = 84/144 (58%), Gaps = 2/144 (1%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKV--KVPTFLVTATQKVWMDVYALPVPGA 436
+ ID+V IGSCT G+ ED AA + G+KV V +V ATQK+++ +
Sbjct: 292 IYIDQVVIGSCTNGRMEDLRKAAAILK--GKKVADNVRVMVVPATQKIYLQCILEGI--- 346
Query: 435 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 256
+ F EAGC +PSCG C+GG A+ + CVSTTNRNF GRMG E
Sbjct: 347 -----LETFVEAGCAVN-TPSCGPCMGGHMGVLAK---GEKCVSTTNRNFVGRMGDVESL 397
Query: 255 IYLASPYTAAASALTGRVADPREF 184
IYLASP TAAASA+ G +A+P +F
Sbjct: 398 IYLASPETAAASAIAGYIANPEKF 421
[91][TOP]
>UniRef100_A8AB09 3-isopropylmalate dehydratase, large subunit n=1 Tax=Ignicoccus
hospitalis KIN4/I RepID=A8AB09_IGNH4
Length = 419
Score = 105 bits (263), Expect = 2e-21
Identities = 64/149 (42%), Positives = 87/149 (58%), Gaps = 2/149 (1%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALP 448
E + ID+ +IGSCT G+ EDF+ AAK+ GRKV V + A+ K +M +
Sbjct: 285 EVEGTPIDQAFIGSCTNGRYEDFVEAAKILK--GRKVAPGVRCIAIPASLKQYMRLLKEG 342
Query: 447 VPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
+ I EAGC A +CG CLGG L +V +S++NRNF GRMGH
Sbjct: 343 I--------IDILTEAGCFV-AHSTCGPCLGGHLGV---LGPGEVAISSSNRNFKGRMGH 390
Query: 267 KEGQIYLASPYTAAASALTGRVADPREFL 181
E ++YLASP T AASA+ G++ADPR++L
Sbjct: 391 PESKVYLASPATVAASAVEGKIADPRKYL 419
[92][TOP]
>UniRef100_B5YEF5 3-isopropylmalate dehydratase, large subunit n=1 Tax=Dictyoglomus
thermophilum H-6-12 RepID=B5YEF5_DICT6
Length = 424
Score = 105 bits (261), Expect = 4e-21
Identities = 63/144 (43%), Positives = 81/144 (56%), Gaps = 1/144 (0%)
Frame = -3
Query: 615 KDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGA 436
KD+ ID+VYIGSCT G+ ED AAK+ V + AT ++M
Sbjct: 289 KDIYIDQVYIGSCTNGRIEDLRIAAKILKGHKVHKDVRLIITPATPNIYMQALK------ 342
Query: 435 GGKTCAQIFEEAGCD-TPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 259
+ +IF EAG TP PSCG CLGG A E + V+TTNRNF GRMGH +
Sbjct: 343 --EGLIEIFLEAGASITP--PSCGPCLGGHLGVLA---EGEKAVATTNRNFVGRMGHPKS 395
Query: 258 QIYLASPYTAAASALTGRVADPRE 187
++YL++P AAASA+ GR+A P E
Sbjct: 396 EVYLSNPAVAAASAILGRIAAPWE 419
[93][TOP]
>UniRef100_C6ML86 Homoaconitate hydratase family protein n=1 Tax=Geobacter sp. M18
RepID=C6ML86_9DELT
Length = 427
Score = 105 bits (261), Expect = 4e-21
Identities = 65/148 (43%), Positives = 86/148 (58%), Gaps = 1/148 (0%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E +D+VY+GSCT G+ ED AA++ V L AT +++ D A
Sbjct: 294 EMAGTPVDQVYLGSCTNGRLEDLRVAAQILKGKKIASNVRGILSPATPQIYKDAVA---- 349
Query: 441 GAGGKTCAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
+ QIF +AG C T +P+CGACLG A E +VC STTNRNF GRMG K
Sbjct: 350 ----EGLIQIFMDAGFCVT--NPTCGACLGMSNGVLA---EGEVCASTTNRNFMGRMG-K 399
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
G ++L SP TAAASA+ G++ADPR++L
Sbjct: 400 GGMVHLLSPATAAASAIEGKLADPRKYL 427
[94][TOP]
>UniRef100_Q8PZT3 3-isopropylmalate dehydratase large subunit 1 n=1
Tax=Methanosarcina mazei RepID=LEUC1_METMA
Length = 391
Score = 105 bits (261), Expect = 4e-21
Identities = 65/145 (44%), Positives = 85/145 (58%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + +D+V+IG+CT G+ ED AA + G+KV V T ++ A++ +
Sbjct: 261 EVEGTHVDQVFIGTCTNGRLEDLEVAASVLK--GKKVTVRTIIIPASRSTLL-------- 310
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
A +I +AG T A+P CG CLG L E +VCVST NRNF GRMG K+
Sbjct: 311 AAIKNGTMEILLKAGV-TLATPGCGPCLGAHQGV---LGEGEVCVSTANRNFKGRMG-KD 365
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
G IYLASP TAAASALTG + DPR+
Sbjct: 366 GFIYLASPATAAASALTGEITDPRK 390
[95][TOP]
>UniRef100_C9L6F6 3-isopropylmalate dehydratase, large subunit n=1 Tax=Blautia
hansenii DSM 20583 RepID=C9L6F6_RUMHA
Length = 425
Score = 104 bits (260), Expect = 5e-21
Identities = 59/142 (41%), Positives = 83/142 (58%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
DV I + IGSCT G+ +D AA++ K V ++ ATQK+++
Sbjct: 293 DVIIQQSVIGSCTNGRIDDLRCAAQILKNRKVKKGVRCIIIPATQKIYLQALE------- 345
Query: 432 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
+ +IF EAG ++P+CG CLGG A E + C+STTNRNF GRMGH + ++
Sbjct: 346 -EGLLKIFIEAGA-VVSTPTCGPCLGGYMGILA---EGERCISTTNRNFVGRMGHVKSEV 400
Query: 252 YLASPYTAAASALTGRVADPRE 187
YLASP AAASA+TG+++ P E
Sbjct: 401 YLASPAVAAASAITGKISSPEE 422
[96][TOP]
>UniRef100_C4G1B4 Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC
49176 RepID=C4G1B4_ABIDE
Length = 421
Score = 104 bits (260), Expect = 5e-21
Identities = 62/147 (42%), Positives = 86/147 (58%), Gaps = 2/147 (1%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALP 448
E D+KID+V IGSCT G+ D AA++ G+KV + ++ ATQ+V++
Sbjct: 286 ETGDIKIDQVVIGSCTNGRISDIRVAAEVMK--GKKVAPGIRVIVIPATQEVYLTSLK-- 341
Query: 447 VPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
+ F +AGC ++P+CG CLGG A + VSTTNRNF GRMGH
Sbjct: 342 ------EGLITTFVQAGCIV-STPTCGPCLGGHMGVLAA---GERAVSTTNRNFVGRMGH 391
Query: 267 KEGQIYLASPYTAAASALTGRVADPRE 187
E ++YLASP AAASA+TG+++ P E
Sbjct: 392 TESEVYLASPAVAAASAITGKISSPEE 418
[97][TOP]
>UniRef100_A5IJM1 3-isopropylmalate dehydratase, large subunit n=2 Tax=Thermotogaceae
RepID=A5IJM1_THEP1
Length = 417
Score = 104 bits (260), Expect = 5e-21
Identities = 59/145 (40%), Positives = 82/145 (56%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + +KID+ IGSCT G+ ED AA++ V ++ +QKV+
Sbjct: 284 EKERIKIDQAVIGSCTNGRIEDLRLAAQILKGRTVSPDVRCIIIPGSQKVYKQALK---- 339
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
+ IF +AGC ++P+CG CLGG A E +V +STTNRNF GRMGH
Sbjct: 340 ----EGLIDIFIDAGCAV-STPTCGPCLGGHMGVLA---EGEVAISTTNRNFVGRMGHPN 391
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
+++LASP AAASA+ G +ADPR+
Sbjct: 392 SKVFLASPAVAAASAIKGYIADPRK 416
[98][TOP]
>UniRef100_A6BFK8 Putative uncharacterized protein n=1 Tax=Dorea longicatena DSM
13814 RepID=A6BFK8_9FIRM
Length = 424
Score = 104 bits (260), Expect = 5e-21
Identities = 61/141 (43%), Positives = 79/141 (56%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGG 430
+KID+V IGSCT G+ ED AA + V +V ATQK++
Sbjct: 292 IKIDQVVIGSCTNGRMEDMRKAAAILQGHTVHPDVRVMVVPATQKIYKQCIR-------- 343
Query: 429 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 250
+ +IF +AGC +PSCG C+GG A + CVSTTNRNF GRMGH + IY
Sbjct: 344 EGLLEIFVDAGCAVN-TPSCGPCMGGHMGVMAA---GEKCVSTTNRNFVGRMGHVDSLIY 399
Query: 249 LASPYTAAASALTGRVADPRE 187
LASP AAASA+ G +A+P +
Sbjct: 400 LASPEVAAASAIAGYIANPEK 420
[99][TOP]
>UniRef100_Q9WZ24 3-isopropylmalate dehydratase large subunit 2 n=2 Tax=Thermotoga
RepID=LEUC2_THEMA
Length = 417
Score = 104 bits (260), Expect = 5e-21
Identities = 59/145 (40%), Positives = 82/145 (56%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + +KID+ IGSCT G+ ED AA++ V ++ +QKV+
Sbjct: 284 EKERIKIDQAVIGSCTNGRIEDLRLAAQILKGRTVSPDVRCIIIPGSQKVYKQALK---- 339
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
+ IF +AGC ++P+CG CLGG A E +V +STTNRNF GRMGH
Sbjct: 340 ----EGLIDIFIDAGCAV-STPTCGPCLGGHMGVLA---EGEVAISTTNRNFVGRMGHPN 391
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
+++LASP AAASA+ G +ADPR+
Sbjct: 392 SKVFLASPAVAAASAIKGYIADPRK 416
[100][TOP]
>UniRef100_C7I822 3-isopropylmalate dehydratase, large subunit n=1 Tax=Thermotoga
naphthophila RKU-10 RepID=C7I822_9THEM
Length = 417
Score = 104 bits (259), Expect = 7e-21
Identities = 58/145 (40%), Positives = 82/145 (56%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + +KID+ IGSCT G+ ED AA++ V ++ +QKV+
Sbjct: 284 EKERIKIDQAVIGSCTNGRIEDLRLAAQILKGRTVSPDVRCIIIPGSQKVYKQALK---- 339
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
+ +F +AGC ++P+CG CLGG A E +V +STTNRNF GRMGH
Sbjct: 340 ----EGLIDVFIDAGCAV-STPTCGPCLGGHMGVLA---EGEVAISTTNRNFVGRMGHPN 391
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
+++LASP AAASA+ G +ADPR+
Sbjct: 392 SKVFLASPAVAAASAIKGYIADPRK 416
[101][TOP]
>UniRef100_Q12TV2 Homoaconitase large subunit n=1 Tax=Methanococcoides burtonii DSM
6242 RepID=Q12TV2_METBU
Length = 413
Score = 104 bits (259), Expect = 7e-21
Identities = 62/144 (43%), Positives = 86/144 (59%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + K+D+V+IG+CT G+ ED AA++ G +V V T ++ A++ + ++
Sbjct: 283 EIEGKKVDQVFIGTCTNGRLEDLEVAAEILK--GEQVAVRTIVIPASRSIMLE------- 333
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
A A+ +AG T SP CG CLGG + E +VC+ST NRNF GRMG K
Sbjct: 334 -AVRNGTAETLLDAGV-TLGSPGCGPCLGGHMGV---IGEGEVCISTANRNFRGRMG-KG 387
Query: 261 GQIYLASPYTAAASALTGRVADPR 190
G IYL+SP TAAASA+TG + DPR
Sbjct: 388 GFIYLSSPATAAASAITGEITDPR 411
[102][TOP]
>UniRef100_A7H0L8 3-isopropylmalate dehydratase large subunit n=1 Tax=Campylobacter
curvus 525.92 RepID=LEUC_CAMC5
Length = 421
Score = 104 bits (259), Expect = 7e-21
Identities = 64/144 (44%), Positives = 85/144 (59%), Gaps = 2/144 (1%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVT--ATQKVWMDVYALPVPG 439
D+ ID+ +IGSCT G+ D AA++ GRKV T L+ ATQK+ +
Sbjct: 291 DIAIDQAFIGSCTNGRLSDLRIAAEILK--GRKVSRKTRLIITPATQKIAL--------A 340
Query: 438 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 259
A + IF EAG ++P+CGACLGG L + CVSTTNRNF GRMG +
Sbjct: 341 AQKEGLMDIFVEAGA-VVSNPTCGACLGGYMGI---LGAGERCVSTTNRNFVGRMGDRTS 396
Query: 258 QIYLASPYTAAASALTGRVADPRE 187
++YLA+ AAASA+ G++ADPRE
Sbjct: 397 EVYLANSAVAAASAIAGKIADPRE 420
[103][TOP]
>UniRef100_C0WAT0 3-isopropylmalate dehydratase n=1 Tax=Acidaminococcus sp. D21
RepID=C0WAT0_9FIRM
Length = 418
Score = 103 bits (258), Expect = 9e-21
Identities = 59/142 (41%), Positives = 81/142 (57%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
D+ ID+V IGSCT G+ ED AAK+ V ++ +Q+V+ + A
Sbjct: 287 DIPIDQVVIGSCTNGRLEDLAIAAKILEGRTVHPDVRCIVIPGSQEVYKE--------AM 338
Query: 432 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
K F +AGC ++P+CG CLGG A + CVSTTNRNF GRMGH + ++
Sbjct: 339 KKGYIDTFIDAGC-VVSTPTCGPCLGGYMGILAA---GERCVSTTNRNFRGRMGHVDSEV 394
Query: 252 YLASPYTAAASALTGRVADPRE 187
YLA P AAASA+ G++A P+E
Sbjct: 395 YLAGPQVAAASAILGKIAAPKE 416
[104][TOP]
>UniRef100_C0D3T2 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
DSM 15981 RepID=C0D3T2_9CLOT
Length = 446
Score = 103 bits (258), Expect = 9e-21
Identities = 63/144 (43%), Positives = 87/144 (60%), Gaps = 2/144 (1%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKV--KVPTFLVTATQKVWMDVYALPVPG 439
DVKID+ IGSCT G+ +D AA++ GRKV V ++ ATQ +++
Sbjct: 315 DVKIDQSVIGSCTNGRIDDMRVAAEILK--GRKVAKNVRCIVIPATQAIYLQ-------- 364
Query: 438 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 259
A + +IF EAG ++P+CG CLGG A + C+STTNRNF GRMGH +
Sbjct: 365 AMREGLLEIFVEAGAIV-STPTCGPCLGGYMGILAA---GERCISTTNRNFVGRMGHVDS 420
Query: 258 QIYLASPYTAAASALTGRVADPRE 187
++YLASP AAASA+TG+++ P E
Sbjct: 421 EVYLASPAVAAASAVTGKISCPCE 444
[105][TOP]
>UniRef100_A5KNQ3 Putative uncharacterized protein n=1 Tax=Ruminococcus torques ATCC
27756 RepID=A5KNQ3_9FIRM
Length = 451
Score = 103 bits (258), Expect = 9e-21
Identities = 62/143 (43%), Positives = 79/143 (55%)
Frame = -3
Query: 615 KDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGA 436
+ VKID+V IGSCT G+ ED AA + V +V ATQK++
Sbjct: 297 EQVKIDQVVIGSCTNGRMEDMRKAAAILKGHTVHPDVRVMVVPATQKIYKQCIK------ 350
Query: 435 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 256
+ IF +AGC +PSCG C+GG A + CVSTTNRNF GRMGH +
Sbjct: 351 --EGLLDIFVDAGCAVN-TPSCGPCMGGHMGVMAA---GEKCVSTTNRNFVGRMGHVDSL 404
Query: 255 IYLASPYTAAASALTGRVADPRE 187
IYLASP AAASA+ G +A+P +
Sbjct: 405 IYLASPEVAAASAIKGYIANPEK 427
[106][TOP]
>UniRef100_O28084 3-isopropylmalate dehydratase large subunit 2 n=1 Tax=Archaeoglobus
fulgidus RepID=LEUC2_ARCFU
Length = 416
Score = 103 bits (258), Expect = 9e-21
Identities = 63/149 (42%), Positives = 90/149 (60%), Gaps = 2/149 (1%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALP 448
E + ++++VYIG+CT G+ D AA++ GRKVK V +V A+++V++
Sbjct: 282 EVEGTEVNQVYIGTCTNGRLSDLEVAARILK--GRKVKEGVRLIVVPASRRVYLQ----- 334
Query: 447 VPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
A K ++F EAG +P CG C+G A + +VC+ST NRNF GRMG+
Sbjct: 335 ---ALDKGLIRVFVEAG-GMVLNPGCGPCVGIHQGILA---DGEVCISTQNRNFKGRMGN 387
Query: 267 KEGQIYLASPYTAAASALTGRVADPREFL 181
+I+LASP TAAASA+ G +ADPREFL
Sbjct: 388 PNAEIFLASPATAAASAVKGYIADPREFL 416
[107][TOP]
>UniRef100_B8E2X0 3-isopropylmalate dehydratase, large subunit n=1 Tax=Dictyoglomus
turgidum DSM 6724 RepID=B8E2X0_DICTD
Length = 424
Score = 103 bits (257), Expect = 1e-20
Identities = 63/144 (43%), Positives = 80/144 (55%), Gaps = 1/144 (0%)
Frame = -3
Query: 615 KDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGA 436
KD+ ID+VYIGSCT G+ ED AAK+ V + AT V+M
Sbjct: 289 KDIYIDQVYIGSCTNGRIEDLRLAAKILKGHKVHKDVRLIVTPATPNVYMQALK------ 342
Query: 435 GGKTCAQIFEEAGCD-TPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 259
+ +IF E G TP PSCG CLGG A E + V+TTNRNF GRMGH +
Sbjct: 343 --EGLIEIFLEVGASITP--PSCGPCLGGHLGVLA---EGEKAVATTNRNFVGRMGHPKS 395
Query: 258 QIYLASPYTAAASALTGRVADPRE 187
++YL++P AAASA+ GR+A P E
Sbjct: 396 EVYLSNPAVAAASAILGRIAAPWE 419
[108][TOP]
>UniRef100_C4ETQ1 3-isopropylmalate dehydratase, large subunit n=1
Tax=Thermanaerovibrio acidaminovorans DSM 6589
RepID=C4ETQ1_9BACT
Length = 420
Score = 103 bits (257), Expect = 1e-20
Identities = 60/147 (40%), Positives = 84/147 (57%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
+ K +I + +IGSCT G+ ED AA + GR+V V T ++ A+ +V+
Sbjct: 288 QVKGAQIHQAFIGSCTNGRIEDLREAATILK--GRQVAVRTIVIPASWRVYRQ------- 338
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
A + + F +AGC ++P CG C+G A + C+ST NRNF GRMG+K+
Sbjct: 339 -AMEEGLLETFLDAGC-VISNPGCGPCMGNHQGILA---PGETCISTANRNFKGRMGNKD 393
Query: 261 GQIYLASPYTAAASALTGRVADPREFL 181
IYLASP T AASA+ G +ADPRE L
Sbjct: 394 SFIYLASPLTVAASAVAGEIADPREVL 420
[109][TOP]
>UniRef100_C0CTF8 Putative uncharacterized protein (Fragment) n=1 Tax=Clostridium
asparagiforme DSM 15981 RepID=C0CTF8_9CLOT
Length = 134
Score = 103 bits (257), Expect = 1e-20
Identities = 65/147 (44%), Positives = 85/147 (57%), Gaps = 2/147 (1%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVT--ATQKVWMDVYALP 448
E V+I + YIGSCTGG+ D AA+L GRK+ L+ A+++++
Sbjct: 1 EQSGVRIHQAYIGSCTGGRYHDLKMAAELLR--GRKIAPGLRLLVSPASREIYNQCLREG 58
Query: 447 VPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
+ ++ EAG AS SCGACLG + T A + +VC+STTNRNF GRMG
Sbjct: 59 I--------LEVLAEAGATVLAS-SCGACLGIHSGTLA---DGEVCISTTNRNFIGRMGS 106
Query: 267 KEGQIYLASPYTAAASALTGRVADPRE 187
K +YLASP T AASALTG + DPRE
Sbjct: 107 KTSSVYLASPVTVAASALTGHITDPRE 133
[110][TOP]
>UniRef100_B5CQV8 Putative uncharacterized protein n=1 Tax=Ruminococcus lactaris ATCC
29176 RepID=B5CQV8_9FIRM
Length = 424
Score = 103 bits (257), Expect = 1e-20
Identities = 60/141 (42%), Positives = 79/141 (56%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGG 430
+KID+V IGSCT G+ ED AA + V ++ ATQK++ +
Sbjct: 292 IKIDQVVIGSCTNGRMEDLRKAAAILKGHTVHPDVRVMVIPATQKIYKECIK-------- 343
Query: 429 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 250
+ IF +AGC +PSCG C+GG A + CVSTTNRNF GRMGH + IY
Sbjct: 344 EGLLDIFVDAGCAVN-TPSCGPCMGGHMGVMAA---GEKCVSTTNRNFVGRMGHVDSLIY 399
Query: 249 LASPYTAAASALTGRVADPRE 187
LASP AAASA+ G +A+P +
Sbjct: 400 LASPEVAAASAIAGCIANPEK 420
[111][TOP]
>UniRef100_C9LTJ0 3-isopropylmalate dehydratase, large subunit n=1 Tax=Selenomonas
sputigena ATCC 35185 RepID=C9LTJ0_9FIRM
Length = 420
Score = 103 bits (256), Expect = 2e-20
Identities = 59/141 (41%), Positives = 79/141 (56%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGG 430
+KID+V IGSCT G+ ED +A L V ++ +Q V+ + L
Sbjct: 290 IKIDQVVIGSCTNGRLEDLEISAGLLKGHEVHPDVRCIVIPGSQAVYQEAMHLGY----- 344
Query: 429 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 250
+F +AGC A+P+CG CLGG L + CVSTTNRNF GRMGH + ++Y
Sbjct: 345 ---IDVFIDAGCAV-AAPTCGPCLGGYMGI---LTAGERCVSTTNRNFRGRMGHVDSEVY 397
Query: 249 LASPYTAAASALTGRVADPRE 187
LA P+ AAASA+ GR+A P E
Sbjct: 398 LAGPHVAAASAILGRIAAPEE 418
[112][TOP]
>UniRef100_C0BZF9 Putative uncharacterized protein n=1 Tax=Clostridium hylemonae DSM
15053 RepID=C0BZF9_9CLOT
Length = 431
Score = 103 bits (256), Expect = 2e-20
Identities = 60/141 (42%), Positives = 79/141 (56%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGG 430
V+ID+V IGSCT G+ ED AA + V ++ ATQK++ +
Sbjct: 299 VRIDQVVIGSCTNGRMEDMRRAAAVLKGHKVHPDVRAMIIPATQKIYKQCIS-------- 350
Query: 429 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 250
+ IF +AGC +PSCG C+GG A + CVSTTNRNF GRMGH + IY
Sbjct: 351 EGLVDIFIDAGCAFN-TPSCGPCMGGHMGVLAA---GEKCVSTTNRNFVGRMGHVDSLIY 406
Query: 249 LASPYTAAASALTGRVADPRE 187
LASP AAASA+ G +A+P +
Sbjct: 407 LASPEVAAASAIAGHIANPEK 427
[113][TOP]
>UniRef100_B1C4Q4 Putative uncharacterized protein n=1 Tax=Clostridium spiroforme DSM
1552 RepID=B1C4Q4_9FIRM
Length = 424
Score = 103 bits (256), Expect = 2e-20
Identities = 64/143 (44%), Positives = 83/143 (58%), Gaps = 2/143 (1%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKV--KVPTFLVTATQKVWMDVYALPVPGA 436
+ ID+V IGSCT G+ D AA + G+KV V +V ATQK+++
Sbjct: 292 IYIDQVVIGSCTNGRISDLRKAAAILK--GKKVARNVRVMVVPATQKIFLQCIV------ 343
Query: 435 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 256
+ A+IF EAGC +PSCG C+GG A+ + CVSTTNRNF GRMG E
Sbjct: 344 --EGLAEIFVEAGCAFN-TPSCGPCMGGHMGVMAK---GEKCVSTTNRNFVGRMGDTEAL 397
Query: 255 IYLASPYTAAASALTGRVADPRE 187
IYLASP AAASA+ G +A+P +
Sbjct: 398 IYLASPEVAAASAIAGYIANPEK 420
[114][TOP]
>UniRef100_B0NJ74 Putative uncharacterized protein n=1 Tax=Clostridium scindens ATCC
35704 RepID=B0NJ74_EUBSP
Length = 424
Score = 103 bits (256), Expect = 2e-20
Identities = 64/143 (44%), Positives = 82/143 (57%), Gaps = 2/143 (1%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVPGA 436
+KID+V IGSCT G+ ED AA + GRKV V ++ ATQK++
Sbjct: 292 IKIDQVVIGSCTNGRMEDMRRAAAVLK--GRKVHPDVRVMVIPATQKIYKQCIK------ 343
Query: 435 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 256
+ IF +AGC +PSCG C+GG A + CVSTTNRNF GRMGH +
Sbjct: 344 --EGLVDIFIDAGCAFN-TPSCGPCMGGHMGVLAA---GEKCVSTTNRNFVGRMGHVDSL 397
Query: 255 IYLASPYTAAASALTGRVADPRE 187
IYLASP AAASA+ G +A+P +
Sbjct: 398 IYLASPEVAAASAIAGCIANPEK 420
[115][TOP]
>UniRef100_A0RMG7 3-isopropylmalate dehydratase large subunit n=1 Tax=Campylobacter
fetus subsp. fetus 82-40 RepID=LEUC_CAMFF
Length = 421
Score = 103 bits (256), Expect = 2e-20
Identities = 63/143 (44%), Positives = 86/143 (60%), Gaps = 2/143 (1%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVT--ATQKVWMDVYALPVPG 439
D+KID+V+IGSCT G+ D AA++ G++V T L+ ATQK+ +
Sbjct: 291 DLKIDQVFIGSCTNGRLSDLRIAARILK--GKRVAKHTRLIITPATQKIAL--------A 340
Query: 438 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 259
A + IF EAG ++P+CGACLGG L + CVSTTNRNF GRMG +
Sbjct: 341 AQKEGLMDIFVEAGA-VVSNPTCGACLGGYMGI---LGAGERCVSTTNRNFVGRMGDRTS 396
Query: 258 QIYLASPYTAAASALTGRVADPR 190
++YLA+ AAASA+ G++ADPR
Sbjct: 397 EVYLANSAVAAASAIAGKIADPR 419
[116][TOP]
>UniRef100_Q74BX5 3-isopropylmalate dehydratase large subunit n=1 Tax=Geobacter
sulfurreducens RepID=LEUC_GEOSL
Length = 427
Score = 102 bits (255), Expect = 2e-20
Identities = 64/148 (43%), Positives = 85/148 (57%), Gaps = 1/148 (0%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E +D+VY+GSCT G+ ED AA++ V L AT K++ D
Sbjct: 294 EIAGTPVDQVYLGSCTNGRLEDLRIAARILKGKKIAPTVRGILSPATPKIYQD------- 346
Query: 441 GAGGKTCAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
A + IF EAG C T +P+CGACLG A E +VC STTNRNF GRMG K
Sbjct: 347 -AMREGLIDIFMEAGFCVT--NPTCGACLGMSNGVLA---EGEVCASTTNRNFMGRMG-K 399
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
G ++L SP T+AA+A+ G++ADPR++L
Sbjct: 400 GGMVHLMSPATSAATAIEGKIADPRKYL 427
[117][TOP]
>UniRef100_A4J182 3-isopropylmalate dehydratase, large subunit n=1
Tax=Desulfotomaculum reducens MI-1 RepID=A4J182_DESRM
Length = 418
Score = 102 bits (254), Expect = 3e-20
Identities = 57/143 (39%), Positives = 84/143 (58%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGG 430
V ID+ IGSCT G+ ED AA++ +V ++ TQ+++ A
Sbjct: 288 VDIDQAVIGSCTNGRMEDLRLAAEILKGKKVHQQVRLIVIPGTQEIYRQ--------AMR 339
Query: 429 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 250
+ +IF +AG ++P+CG CLGG A+ + C++TTNRNF GRMGH E ++Y
Sbjct: 340 EGLFEIFLDAGA-VVSTPTCGPCLGGHMGILAK---GERCIATTNRNFVGRMGHAESEVY 395
Query: 249 LASPYTAAASALTGRVADPREFL 181
LA+P AAASA+TGR++ P+E L
Sbjct: 396 LANPAVAAASAITGRISHPQEVL 418
[118][TOP]
>UniRef100_C8PKG7 3-isopropylmalate dehydratase large subunit n=1 Tax=Campylobacter
gracilis RM3268 RepID=C8PKG7_9PROT
Length = 421
Score = 102 bits (254), Expect = 3e-20
Identities = 63/144 (43%), Positives = 86/144 (59%), Gaps = 2/144 (1%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVT--ATQKVWMDVYALPVPG 439
D+ +D+V+IGSCT G+ D AA++ GRKV T L+ ATQK+ +
Sbjct: 291 DIAVDQVFIGSCTNGRLSDLRIAAQILK--GRKVARKTRLIITPATQKIAL--------A 340
Query: 438 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 259
A + IF EAG ++P+CGACLGG L + CVSTTNRNF GRMG +
Sbjct: 341 AQKEGLWDIFVEAGA-VVSNPTCGACLGGYMGI---LGVGERCVSTTNRNFVGRMGDRTS 396
Query: 258 QIYLASPYTAAASALTGRVADPRE 187
++YLA+ AAASA+ G++ADPR+
Sbjct: 397 EVYLANSAVAAASAVAGKIADPRD 420
[119][TOP]
>UniRef100_C3RJS7 Putative uncharacterized protein n=1 Tax=Mollicutes bacterium D7
RepID=C3RJS7_9MOLU
Length = 422
Score = 102 bits (254), Expect = 3e-20
Identities = 61/141 (43%), Positives = 79/141 (56%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGG 430
+ ID+V IGSCT G+ D AA + V +V ATQK+++
Sbjct: 290 IMIDQVVIGSCTNGRLSDLRKAAAILKGKQVAKNVRVMVVPATQKIFVQCIH-------- 341
Query: 429 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 250
+ A+IF EAGC +PSCG C+GG A+ + CVSTTNRNF GRMG E IY
Sbjct: 342 EGLAEIFVEAGCAFN-TPSCGPCMGGHMGVMAK---GEKCVSTTNRNFVGRMGDTEALIY 397
Query: 249 LASPYTAAASALTGRVADPRE 187
LASP AAASA+ G +A+P +
Sbjct: 398 LASPEVAAASAIAGYIANPEK 418
[120][TOP]
>UniRef100_B9D2G7 3-isopropylmalate dehydratase, large subunit n=1 Tax=Campylobacter
rectus RM3267 RepID=B9D2G7_WOLRE
Length = 424
Score = 102 bits (254), Expect = 3e-20
Identities = 63/144 (43%), Positives = 85/144 (59%), Gaps = 2/144 (1%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVT--ATQKVWMDVYALPVPG 439
D+ ID+ +IGSCT G+ D AA++ GRKV T L+ ATQK+ +
Sbjct: 294 DIAIDQAFIGSCTNGRLSDLRIAAEILK--GRKVARKTRLIITPATQKIALQ-------- 343
Query: 438 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 259
A + IF EAG ++P+CGACLGG L + CVSTTNRNF GRMG +
Sbjct: 344 AQKEGLMDIFAEAGA-VVSNPTCGACLGGYMGI---LGVGERCVSTTNRNFVGRMGDRTS 399
Query: 258 QIYLASPYTAAASALTGRVADPRE 187
++YLA+ AAASA+ G++ADPR+
Sbjct: 400 EVYLANSAVAAASAVVGKIADPRD 423
[121][TOP]
>UniRef100_B0N943 Putative uncharacterized protein n=1 Tax=Clostridium ramosum DSM
1402 RepID=B0N943_9FIRM
Length = 424
Score = 102 bits (254), Expect = 3e-20
Identities = 61/141 (43%), Positives = 79/141 (56%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGG 430
+ ID+V IGSCT G+ D AA + V +V ATQK+++
Sbjct: 292 IMIDQVVIGSCTNGRLSDLRKAAAILKGKQVAKNVRVMVVPATQKIFVQCIH-------- 343
Query: 429 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 250
+ A+IF EAGC +PSCG C+GG A+ + CVSTTNRNF GRMG E IY
Sbjct: 344 EGLAEIFVEAGCAFN-TPSCGPCMGGHMGVMAK---GEKCVSTTNRNFVGRMGDTEALIY 399
Query: 249 LASPYTAAASALTGRVADPRE 187
LASP AAASA+ G +A+P +
Sbjct: 400 LASPEVAAASAIAGYIANPEK 420
[122][TOP]
>UniRef100_B0G7V2 Putative uncharacterized protein n=1 Tax=Dorea formicigenerans ATCC
27755 RepID=B0G7V2_9FIRM
Length = 425
Score = 102 bits (254), Expect = 3e-20
Identities = 60/141 (42%), Positives = 78/141 (55%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGG 430
+KID+V IGSCT G+ ED AA + V ++ ATQK++
Sbjct: 292 IKIDQVVIGSCTNGRMEDMRKAAAILKGHKVHEDVRVMVIPATQKIYKQCIH-------- 343
Query: 429 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 250
+ IF +AGC +PSCG C+GG A + CVSTTNRNF GRMGH + IY
Sbjct: 344 EGLMDIFVDAGCAVN-TPSCGPCMGGHMGVMAA---GEKCVSTTNRNFVGRMGHVDSLIY 399
Query: 249 LASPYTAAASALTGRVADPRE 187
LASP AAASA+ G +A+P +
Sbjct: 400 LASPEVAAASAIAGCIANPEK 420
[123][TOP]
>UniRef100_A7B6Z9 Putative uncharacterized protein n=1 Tax=Ruminococcus gnavus ATCC
29149 RepID=A7B6Z9_RUMGN
Length = 425
Score = 102 bits (254), Expect = 3e-20
Identities = 60/139 (43%), Positives = 77/139 (55%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGG 430
+KID+V IGSCT G+ ED AA + V ++ ATQK++
Sbjct: 292 IKIDQVVIGSCTNGRMEDMRKAAAILKGHTVHPDVRVMVIPATQKIYKQCIK-------- 343
Query: 429 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 250
+ IF +AGC +PSCG C+GG A + CVSTTNRNF GRMGH + IY
Sbjct: 344 EGLLDIFVDAGCAVN-TPSCGPCMGGHMGVMAA---GERCVSTTNRNFVGRMGHVDSLIY 399
Query: 249 LASPYTAAASALTGRVADP 193
LASP AAASA+ G +A+P
Sbjct: 400 LASPEVAAASAIAGYIANP 418
[124][TOP]
>UniRef100_A5ZAM9 Putative uncharacterized protein n=1 Tax=Eubacterium ventriosum
ATCC 27560 RepID=A5ZAM9_9FIRM
Length = 421
Score = 102 bits (254), Expect = 3e-20
Identities = 60/145 (41%), Positives = 81/145 (55%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E DVKID+V IGSCT G+ ED AAK+ V + ATQ +++ +
Sbjct: 286 EVGDVKIDQVVIGSCTNGRIEDMRTAAKILEGREVAKGVRCIVFPATQAIYLQCIEEGI- 344
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
F +AGC ++P+CG CLGG A+ + V+TTNRNF GRMG E
Sbjct: 345 -------MTTFIKAGCAV-STPTCGPCLGGHMGILAK---GERAVATTNRNFVGRMGDPE 393
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
++YLASP AAASA+TG+++ P E
Sbjct: 394 SEVYLASPAVAAASAITGKISGPEE 418
[125][TOP]
>UniRef100_B1L3C3 Homoaconitate hydratase family protein n=1 Tax=Candidatus
Korarchaeum cryptofilum OPF8 RepID=B1L3C3_KORCO
Length = 384
Score = 102 bits (254), Expect = 3e-20
Identities = 59/143 (41%), Positives = 85/143 (59%), Gaps = 2/143 (1%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVPG 439
D +ID+ +IGSCTGG+ +D AA++ GR+VK V ++ A+++++++ +
Sbjct: 253 DAEIDQAFIGSCTGGRLKDLEVAARILR--GRRVKEGVRLIVIPASRRIYLEALRRGI-- 308
Query: 438 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 259
I E+G T PSCG CLG A E +V +ST+NRNF GRMGH E
Sbjct: 309 ------IDILIESGA-TIGPPSCGPCLGAHLGVLA---EGEVAISTSNRNFRGRMGHPES 358
Query: 258 QIYLASPYTAAASALTGRVADPR 190
++YLAS T AASA+ GR+ DPR
Sbjct: 359 RVYLASAATVAASAVEGRIVDPR 381
[126][TOP]
>UniRef100_A8ABG2 3-isopropylmalate dehydratase n=1 Tax=Ignicoccus hospitalis KIN4/I
RepID=A8ABG2_IGNH4
Length = 429
Score = 102 bits (254), Expect = 3e-20
Identities = 59/150 (39%), Positives = 89/150 (59%), Gaps = 2/150 (1%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPT--FLVTATQKVWMDVYALP 448
E + +++D+V+IGSCT G+ ED AA++ G+KV T ++TA++ V++
Sbjct: 286 EVEGIEVDQVFIGSCTNGRLEDVAVAARILK--GKKVAPNTRCIVITASRNVYLQALK-- 341
Query: 447 VPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
K + EAGC +CG C+G Y L +V + TTNRNF GR GH
Sbjct: 342 ------KGYVDVLTEAGCLVTFG-TCGPCVGAH---YGVLGPNEVGLFTTNRNFRGRSGH 391
Query: 267 KEGQIYLASPYTAAASALTGRVADPREFLQ 178
+ ++YLASP TAAASA+ G++ADPR++L+
Sbjct: 392 RTSKVYLASPATAAASAVEGKIADPRKYLK 421
[127][TOP]
>UniRef100_A6Q5L6 3-isopropylmalate dehydratase large subunit n=1 Tax=Nitratiruptor
sp. SB155-2 RepID=LEUC_NITSB
Length = 421
Score = 102 bits (254), Expect = 3e-20
Identities = 63/144 (43%), Positives = 87/144 (60%), Gaps = 2/144 (1%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVT--ATQKVWMDVYALPVPG 439
D+K+D+V+IGSCT G+ D AA++ GRKV T ++ ATQK+ +
Sbjct: 291 DLKVDQVFIGSCTNGRLSDIAIAAEILK--GRKVARHTRMIVTPATQKILKE-------- 340
Query: 438 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 259
A + I +AG ++P+CGACLGG A + + CVSTTNRNF GRMG +
Sbjct: 341 AEKRGYIDILIDAGA-VVSNPTCGACLGGYMGILA---DNERCVSTTNRNFVGRMGARTS 396
Query: 258 QIYLASPYTAAASALTGRVADPRE 187
+IYLA+ AAASA+ G++ADPRE
Sbjct: 397 EIYLANSAVAAASAVAGKIADPRE 420
[128][TOP]
>UniRef100_A5G7U4 3-isopropylmalate dehydratase large subunit n=1 Tax=Geobacter
uraniireducens Rf4 RepID=LEUC_GEOUR
Length = 427
Score = 102 bits (254), Expect = 3e-20
Identities = 65/148 (43%), Positives = 85/148 (57%), Gaps = 1/148 (0%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E +D+VY+GSCT G+ ED AA++ V L AT KV+ D
Sbjct: 294 EMAGTPVDQVYLGSCTNGRLEDLRVAAEILKGKKIAPTVRAILSPATPKVYSD------- 346
Query: 441 GAGGKTCAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
A + IF EAG C T +P+CGACLG A E +VC STTNRNF GRMG K
Sbjct: 347 -ALHEGLIDIFMEAGFCVT--NPTCGACLGMSNGVLA---EGEVCASTTNRNFMGRMG-K 399
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
G ++L SP T+AA+A+ G++ADPR++L
Sbjct: 400 GGMVHLMSPATSAATAIEGKMADPRKYL 427
[129][TOP]
>UniRef100_UPI00016C5FE1 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
difficile QCD-97b34 RepID=UPI00016C5FE1
Length = 425
Score = 102 bits (253), Expect = 3e-20
Identities = 61/147 (41%), Positives = 84/147 (57%), Gaps = 2/147 (1%)
Frame = -3
Query: 615 KDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVP 442
KD+KID+V IGSCT G+ D A++ G+KV V + TQKV+++
Sbjct: 293 KDIKIDQVVIGSCTNGRISDLEVVAEIMK--GKKVADGVRVMIFPGTQKVYLEAIE---- 346
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
K F EAG ++P+CG CLGG A + +STTNRNF GRMGH +
Sbjct: 347 ----KGYITTFIEAGAAV-STPTCGPCLGGHMGILAA---GEKSISTTNRNFVGRMGHVD 398
Query: 261 GQIYLASPYTAAASALTGRVADPREFL 181
++YLASP AAASA+TG+++ P E +
Sbjct: 399 SEVYLASPAVAAASAITGKISKPSEII 425
[130][TOP]
>UniRef100_UPI00006DC4EC hypothetical protein CdifQ_04001012 n=1 Tax=Clostridium difficile
QCD-32g58 RepID=UPI00006DC4EC
Length = 191
Score = 102 bits (253), Expect = 3e-20
Identities = 61/147 (41%), Positives = 84/147 (57%), Gaps = 2/147 (1%)
Frame = -3
Query: 615 KDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVP 442
KD+KID+V IGSCT G+ D A++ G+KV V + TQKV+++
Sbjct: 59 KDIKIDQVVIGSCTNGRISDLEVVAEIMK--GKKVADGVRVMIFPGTQKVYLEAIE---- 112
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
K F EAG ++P+CG CLGG A + +STTNRNF GRMGH +
Sbjct: 113 ----KGYITTFIEAGAAV-STPTCGPCLGGHMGILAA---GEKSISTTNRNFVGRMGHVD 164
Query: 261 GQIYLASPYTAAASALTGRVADPREFL 181
++YLASP AAASA+TG+++ P E +
Sbjct: 165 SEVYLASPAVAAASAITGKISKPSEII 191
[131][TOP]
>UniRef100_Q6ALT9 Probable 3-isopropylmalate dehydratase, large subunit n=1
Tax=Desulfotalea psychrophila RepID=Q6ALT9_DESPS
Length = 427
Score = 102 bits (253), Expect = 3e-20
Identities = 60/142 (42%), Positives = 83/142 (58%)
Frame = -3
Query: 606 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGGK 427
K+D++YIGSCT G+ ED AAA + V + AT K +Y++ + +
Sbjct: 299 KVDQIYIGSCTNGRIEDLRAAASILKGRTLATGVRGIVTPATPK----IYSMALE----E 350
Query: 426 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 247
+IF +AG +P+CGACLG + A E +VC STTNRNF GRMG K G ++L
Sbjct: 351 GIIKIFMDAGF-CVLNPTCGACLGMSSGVLA---EGEVCASTTNRNFNGRMG-KGGMVHL 405
Query: 246 ASPYTAAASALTGRVADPREFL 181
SPY+A A+TG + DPR+FL
Sbjct: 406 MSPYSATVGAVTGTITDPRQFL 427
[132][TOP]
>UniRef100_A1ALN5 3-isopropylmalate dehydratase, large subunit n=1 Tax=Pelobacter
propionicus DSM 2379 RepID=A1ALN5_PELPD
Length = 427
Score = 102 bits (253), Expect = 3e-20
Identities = 65/148 (43%), Positives = 85/148 (57%), Gaps = 1/148 (0%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E K+D++Y+GSCT G+ ED AA + V L AT KV+ +
Sbjct: 294 ELAGTKVDQIYLGSCTNGRLEDLRIAAGILKGKKLAPHVRGILSPATPKVYQE------- 346
Query: 441 GAGGKTCAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
A + +IF EAG C T +P+CGACLG A E +VC +TTNRNF GRMG K
Sbjct: 347 -ALKEGLMEIFMEAGFCIT--NPTCGACLGMSNGVLA---EGEVCAATTNRNFMGRMG-K 399
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
G ++L SP TAAASA+ G +ADPR++L
Sbjct: 400 GGMVHLMSPATAAASAIEGVIADPRKYL 427
[133][TOP]
>UniRef100_C9XME3 3-isopropylmalate dehydratase large subunit n=2 Tax=Clostridium
difficile RepID=C9XME3_CLODI
Length = 364
Score = 102 bits (253), Expect = 3e-20
Identities = 61/147 (41%), Positives = 84/147 (57%), Gaps = 2/147 (1%)
Frame = -3
Query: 615 KDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVP 442
KD+KID+V IGSCT G+ D A++ G+KV V + TQKV+++
Sbjct: 232 KDIKIDQVVIGSCTNGRISDLEVVAEIMK--GKKVADGVRVMIFPGTQKVYLEAIE---- 285
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
K F EAG ++P+CG CLGG A + +STTNRNF GRMGH +
Sbjct: 286 ----KGYITTFIEAGAAV-STPTCGPCLGGHMGILAA---GEKSISTTNRNFVGRMGHVD 337
Query: 261 GQIYLASPYTAAASALTGRVADPREFL 181
++YLASP AAASA+TG+++ P E +
Sbjct: 338 SEVYLASPAVAAASAITGKISKPSEII 364
[134][TOP]
>UniRef100_C6RH21 3-isopropylmalate dehydratase, large subunit n=1 Tax=Campylobacter
showae RM3277 RepID=C6RH21_9PROT
Length = 424
Score = 102 bits (253), Expect = 3e-20
Identities = 63/144 (43%), Positives = 85/144 (59%), Gaps = 2/144 (1%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVT--ATQKVWMDVYALPVPG 439
D+ ID+ +IGSCT G+ D AA++ GRKV T L+ ATQK+ +
Sbjct: 294 DIAIDQAFIGSCTNGRLSDLRIAAEILK--GRKVARKTRLIITPATQKIALQ-------- 343
Query: 438 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 259
A + IF EAG ++P+CGACLGG L + CVSTTNRNF GRMG +
Sbjct: 344 AQKEGLMDIFAEAGA-VVSNPTCGACLGGYMGI---LGVGERCVSTTNRNFVGRMGDRTS 399
Query: 258 QIYLASPYTAAASALTGRVADPRE 187
++YLA+ AAASA+ G++ADPR+
Sbjct: 400 EVYLANSAVAAASAVMGKIADPRD 423
[135][TOP]
>UniRef100_C2A003 3-isopropylmalate dehydratase, large subunit n=1
Tax=Sulfurospirillum deleyianum DSM 6946
RepID=C2A003_SULDE
Length = 421
Score = 102 bits (253), Expect = 3e-20
Identities = 64/143 (44%), Positives = 86/143 (60%), Gaps = 2/143 (1%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVT--ATQKVWMDVYALPVPG 439
D+ ID+V+IGSCT G+ ED AA + GRKV T L+ ATQK+ +
Sbjct: 291 DLAIDQVFIGSCTNGRLEDLRIAASILK--GRKVARKTRLIITPATQKISLQ-------- 340
Query: 438 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 259
A + +IF EAG ++P+CGACLGG L + + CV+TTNRNF GRMG +
Sbjct: 341 AQKEGLVEIFIEAGA-VFSNPTCGACLGGYMGI---LGKNERCVATTNRNFVGRMGDRTS 396
Query: 258 QIYLASPYTAAASALTGRVADPR 190
+IYLA+ AAASA+ G++ DPR
Sbjct: 397 EIYLANSAVAAASAVMGKITDPR 419
[136][TOP]
>UniRef100_B6FST2 Putative uncharacterized protein n=1 Tax=Clostridium nexile DSM
1787 RepID=B6FST2_9CLOT
Length = 438
Score = 102 bits (253), Expect = 3e-20
Identities = 60/145 (41%), Positives = 80/145 (55%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + +KID+V IGSCT G+ ED AA + V ++ ATQK+++
Sbjct: 302 EMEPIKIDQVVIGSCTNGRMEDMRRAAAVLKGHKVHPDVRVMVIPATQKIYLQCIE---- 357
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
+ F E+GC +PSCG C+GG A + CVSTTNRNF GRMGH +
Sbjct: 358 ----EGLVTTFIESGCAFN-TPSCGPCMGGHMGVMAA---GEKCVSTTNRNFVGRMGHVD 409
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
IYLASP AAASA+ G +A+P +
Sbjct: 410 SLIYLASPEVAAASAIAGCIANPEK 434
[137][TOP]
>UniRef100_A6Q6J8 3-isopropylmalate dehydratase large subunit n=1 Tax=Sulfurovum sp.
NBC37-1 RepID=LEUC_SULNB
Length = 426
Score = 102 bits (253), Expect = 3e-20
Identities = 63/144 (43%), Positives = 86/144 (59%), Gaps = 2/144 (1%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVT--ATQKVWMDVYALPVPG 439
D+KID+V IGSCT G+ ED AA++ G++V T ++ ATQK+ M
Sbjct: 296 DLKIDQVMIGSCTNGRIEDLRIAAEIMK--GKRVAKHTRMIVTPATQKILMQ-------- 345
Query: 438 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 259
A + I EAG ++P+CGACLGG L + + CV+TTNRNF GRMG +
Sbjct: 346 AQHEGLMDILIEAGA-VVSNPTCGACLGGYMGI---LGDGERCVATTNRNFVGRMGARTS 401
Query: 258 QIYLASPYTAAASALTGRVADPRE 187
+IYLA+ AAASA+ G++ DPRE
Sbjct: 402 EIYLANSAVAAASAIAGKIVDPRE 425
[138][TOP]
>UniRef100_Q39W70 3-isopropylmalate dehydratase large subunit n=1 Tax=Geobacter
metallireducens GS-15 RepID=LEUC_GEOMG
Length = 427
Score = 102 bits (253), Expect = 3e-20
Identities = 63/142 (44%), Positives = 83/142 (58%), Gaps = 1/142 (0%)
Frame = -3
Query: 603 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGGKT 424
+D+VY+GSCT G+ ED AA++ V L AT K++ D A +
Sbjct: 300 VDQVYLGSCTNGRLEDLRIAARILKGKKIAPSVRGILSPATPKIYKDAMA--------EG 351
Query: 423 CAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 247
IF EAG C T +P+CGACLG A E +VC STTNRNF GRMG K G ++L
Sbjct: 352 LIDIFMEAGFCVT--NPTCGACLGMSNGVLA---EGEVCASTTNRNFMGRMG-KGGMVHL 405
Query: 246 ASPYTAAASALTGRVADPREFL 181
SP T+AA+A+ G +ADPR++L
Sbjct: 406 MSPATSAATAIEGVIADPRKYL 427
[139][TOP]
>UniRef100_Q18AJ2 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
difficile 630 RepID=LEUC_CLOD6
Length = 425
Score = 102 bits (253), Expect = 3e-20
Identities = 61/147 (41%), Positives = 84/147 (57%), Gaps = 2/147 (1%)
Frame = -3
Query: 615 KDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVP 442
KD+KID+V IGSCT G+ D A++ G+KV V + TQKV+++
Sbjct: 293 KDIKIDQVVIGSCTNGRISDLEVVAEIMK--GKKVADGVRVMIFPGTQKVYLEAIE---- 346
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
K F EAG ++P+CG CLGG A + +STTNRNF GRMGH +
Sbjct: 347 ----KGYITTFIEAGAAV-STPTCGPCLGGHMGILAA---GEKSISTTNRNFVGRMGHVD 398
Query: 261 GQIYLASPYTAAASALTGRVADPREFL 181
++YLASP AAASA+TG+++ P E +
Sbjct: 399 SEVYLASPAVAAASAITGKISKPSEII 425
[140][TOP]
>UniRef100_C5CJ10 Homoaconitate hydratase family protein n=1 Tax=Kosmotoga olearia
TBF 19.5.1 RepID=C5CJ10_KOSOT
Length = 417
Score = 101 bits (252), Expect = 4e-20
Identities = 56/147 (38%), Positives = 87/147 (59%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + +KID+V+IG+CT G+ ED AA + + V ++ A+++V++
Sbjct: 282 EVEGIKIDQVFIGTCTNGRLEDLRVAASILKGREKHPDVRLIVIPASKEVYLKALE---- 337
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
+ +IF E+G T +P CG C+G L + + +ST NRNF GRMG+ +
Sbjct: 338 ----EGLIKIFVESGA-TVLAPGCGPCVGVHQGV---LGDGERVLSTQNRNFKGRMGNPK 389
Query: 261 GQIYLASPYTAAASALTGRVADPREFL 181
+I+LASP TAAASA+TG++ DPR+FL
Sbjct: 390 AEIFLASPATAAASAITGKITDPRKFL 416
[141][TOP]
>UniRef100_B1QZX5 3-isopropylmalate dehydratase, large subunit n=2 Tax=Clostridium
butyricum RepID=B1QZX5_CLOBU
Length = 419
Score = 101 bits (252), Expect = 4e-20
Identities = 57/140 (40%), Positives = 78/140 (55%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
DVKID+V IGSCT G+ D A + + ++ TQK+++ +
Sbjct: 289 DVKIDQVVIGSCTNGRISDLRVARDILKGKKVDKTIRCIVIPGTQKIYLQALEEGI---- 344
Query: 432 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
+ EAG ++P+CG CLGG A+ + CVSTTNRNF GRMGH E ++
Sbjct: 345 ----IKDLIEAGAIV-STPTCGPCLGGHMGILAK---DERCVSTTNRNFVGRMGHVESEV 396
Query: 252 YLASPYTAAASALTGRVADP 193
YLASP AAASA+TG++ DP
Sbjct: 397 YLASPAVAAASAITGKITDP 416
[142][TOP]
>UniRef100_Q1IZK5 3-isopropylmalate dehydratase large subunit n=1 Tax=Deinococcus
geothermalis DSM 11300 RepID=Q1IZK5_DEIGD
Length = 431
Score = 101 bits (251), Expect = 6e-20
Identities = 61/144 (42%), Positives = 80/144 (55%), Gaps = 2/144 (1%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVPGA 436
+ I Y+GSCT G+ D A++ GR+V V +V ATQ +W A
Sbjct: 291 IPITHAYVGSCTNGRIGDLRDVARILK--GRRVADGVQMIVVPATQAIWKQ--------A 340
Query: 435 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 256
+ +IF EAG + PSCGACLG + L VC+S++NRNF GRMG Q
Sbjct: 341 AQEGLLEIFVEAGASV-SYPSCGACLGMHSGV---LGPGDVCISSSNRNFVGRMGDPSAQ 396
Query: 255 IYLASPYTAAASALTGRVADPREF 184
IYLASP T AASA+ G ++DPRE+
Sbjct: 397 IYLASPATVAASAVAGYISDPREY 420
[143][TOP]
>UniRef100_Q0W1Q4 3-isopropylmalate dehydratase, large subunit n=1 Tax=uncultured
methanogenic archaeon RC-I RepID=Q0W1Q4_UNCMA
Length = 414
Score = 101 bits (251), Expect = 6e-20
Identities = 59/151 (39%), Positives = 82/151 (54%), Gaps = 4/151 (2%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVY----A 454
E + +D+V IGSCT G+ ED AA + GRKV+ T ++ A++ V +D A
Sbjct: 283 EVEGTHVDQVLIGSCTNGRYEDLAGAAAILK--GRKVRCRTLIIPASRSVMLDAVQTGVA 340
Query: 453 LPVPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRM 274
+ AG C +P CG CLGG A E + C++TTNRNF GRM
Sbjct: 341 ADLLAAGATIC-------------NPGCGPCLGGHMGVLA---EGEACLATTNRNFRGRM 384
Query: 273 GHKEGQIYLASPYTAAASALTGRVADPREFL 181
G K +YL SP TAAA+A+ G++ DPR ++
Sbjct: 385 G-KGADVYLGSPLTAAATAINGKITDPRRYI 414
[144][TOP]
>UniRef100_A4WMI6 3-isopropylmalate dehydratase large subunit n=1 Tax=Pyrobaculum
arsenaticum DSM 13514 RepID=LEUC_PYRAR
Length = 415
Score = 101 bits (251), Expect = 6e-20
Identities = 58/149 (38%), Positives = 85/149 (57%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RE + V++D+V+IGSCT G+ D AA++ GR+VK + A+ +V+ L
Sbjct: 280 REVEGVEVDQVFIGSCTNGRLRDIATAARILK--GRRVKTRCIAIPASYEVFKTAMKLGY 337
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
+ EAGC +CG CLGG + +V ++T+NRNF GR+GH
Sbjct: 338 --------IDVLTEAGCVVTYG-TCGPCLGGH---FGVAGPGEVHLTTSNRNFKGRVGHP 385
Query: 264 EGQIYLASPYTAAASALTGRVADPREFLQ 178
E +IYLA+P AAA+A GR+ADPR +L+
Sbjct: 386 EAKIYLANPAVAAATAAEGRIADPRPYLK 414
[145][TOP]
>UniRef100_A9KT79 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
phytofermentans ISDg RepID=LEUC_CLOPH
Length = 421
Score = 101 bits (251), Expect = 6e-20
Identities = 61/148 (41%), Positives = 85/148 (57%), Gaps = 2/148 (1%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYAL 451
+E +V+ID+V IGSCT G+ D AAK+ GRKV + + ATQ +++
Sbjct: 285 KEAGEVRIDQVVIGSCTNGRIGDLRIAAKVLE--GRKVAKGMRAIVFPATQAIYLQAIE- 341
Query: 450 PVPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMG 271
+ Q F +AGC ++P+CG CLGG A + STTNRNF GRMG
Sbjct: 342 -------EGLIQTFIKAGC-VVSTPTCGPCLGGHMGILAA---GERAASTTNRNFVGRMG 390
Query: 270 HKEGQIYLASPYTAAASALTGRVADPRE 187
H E ++YL SP AAASA+TG++++P E
Sbjct: 391 HVESEVYLCSPAVAAASAVTGKISEPSE 418
[146][TOP]
>UniRef100_A6LPX4 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
beijerinckii NCIMB 8052 RepID=LEUC_CLOB8
Length = 419
Score = 101 bits (251), Expect = 6e-20
Identities = 61/142 (42%), Positives = 81/142 (57%), Gaps = 2/142 (1%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVPG 439
DV ID+V IGSCT G+ D A + G+KVK + ++ TQK+++ +
Sbjct: 289 DVAIDQVVIGSCTNGRISDLRMARDILK--GKKVKKGIRCIVIPGTQKIYLQAIKEGI-- 344
Query: 438 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 259
EAG ++P+CG CLGG A+ + CVSTTNRNF GRMGH E
Sbjct: 345 ------VTDLVEAGAAF-STPTCGPCLGGHMGILAK---GERCVSTTNRNFVGRMGHVES 394
Query: 258 QIYLASPYTAAASALTGRVADP 193
++YLASP AAASALTG++ DP
Sbjct: 395 EVYLASPAVAAASALTGKITDP 416
[147][TOP]
>UniRef100_C1CVE2 Putative 3-isopropylmalate dehydratase, large subunit
(Isopropylmalate isomerase) (Alpha-IPM isomerase) n=1
Tax=Deinococcus deserti VCD115 RepID=C1CVE2_DEIDV
Length = 426
Score = 100 bits (250), Expect = 8e-20
Identities = 60/144 (41%), Positives = 80/144 (55%), Gaps = 2/144 (1%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVPGA 436
+ + Y+GSCT G+ D A++ GRKV V +V ATQ +W A
Sbjct: 291 IAVTHAYVGSCTNGRIGDLREVARILK--GRKVADGVQMIVVPATQAIWKQ--------A 340
Query: 435 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 256
+ +IF +AG + PSCGACLG + L VC+S++NRNF GRMG Q
Sbjct: 341 AQEGLMEIFVDAGASV-SYPSCGACLGMHSGV---LGPDDVCISSSNRNFVGRMGDPTAQ 396
Query: 255 IYLASPYTAAASALTGRVADPREF 184
IYLASP T AASA+ G ++DPRE+
Sbjct: 397 IYLASPATVAASAVAGFISDPREY 420
[148][TOP]
>UniRef100_B9M5E2 Homoaconitate hydratase family protein n=1 Tax=Geobacter sp. FRC-32
RepID=B9M5E2_GEOSF
Length = 427
Score = 100 bits (250), Expect = 8e-20
Identities = 62/142 (43%), Positives = 83/142 (58%), Gaps = 1/142 (0%)
Frame = -3
Query: 603 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGGKT 424
+D+VY+GSCT G+ ED AA + V L AT K++ D A +
Sbjct: 300 VDQVYLGSCTNGRLEDLRIAAAILKGKKIASSVRAILSPATPKIYSD--------ALNEG 351
Query: 423 CAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 247
IF +AG C T +P+CGACLG A E +VC STTNRNF GRMG K G ++L
Sbjct: 352 LIAIFMDAGFCVT--NPTCGACLGMSNGVLA---EGEVCASTTNRNFMGRMG-KGGMVHL 405
Query: 246 ASPYTAAASALTGRVADPREFL 181
SP T+AA+A+ G++ADPR++L
Sbjct: 406 MSPATSAATAIEGKIADPRKYL 427
[149][TOP]
>UniRef100_B1C9W1 Putative uncharacterized protein n=1 Tax=Anaerofustis
stercorihominis DSM 17244 RepID=B1C9W1_9FIRM
Length = 424
Score = 100 bits (250), Expect = 8e-20
Identities = 60/152 (39%), Positives = 83/152 (54%), Gaps = 4/152 (2%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDV----YA 454
E V ID+ IGSCT G+ ED AA + KV T ++ ATQK+++D Y
Sbjct: 286 EAGKVYIDQAVIGSCTNGRLEDIKMAADILRGKQVDKKVRTIVIPATQKIYLDSIKLGYV 345
Query: 453 LPVPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRM 274
+ AG IF ++P+CG CLGG A + +STTNRNF GRM
Sbjct: 346 EDIVNAGA-----IF--------STPTCGPCLGGHMGILAA---GEKAISTTNRNFVGRM 389
Query: 273 GHKEGQIYLASPYTAAASALTGRVADPREFLQ 178
GH + ++YL+SP AAASA+ G +ADP + ++
Sbjct: 390 GHVDSEVYLSSPAVAAASAIAGYIADPEKVMK 421
[150][TOP]
>UniRef100_Q9RTI6 3-isopropylmalate dehydratase large subunit 2 n=1 Tax=Deinococcus
radiodurans RepID=LEUC2_DEIRA
Length = 431
Score = 100 bits (250), Expect = 8e-20
Identities = 59/144 (40%), Positives = 80/144 (55%), Gaps = 2/144 (1%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVPGA 436
+++ Y+GSCT G+ D A++ GRKV V +V ATQ +W A
Sbjct: 291 IRVTHAYVGSCTNGRITDLRDVARILK--GRKVAQDVQMIVVPATQAIWKQ--------A 340
Query: 435 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 256
+ +IF +AG + PSCGACLG + L +C+S++NRNF GRMG Q
Sbjct: 341 AQEGLLEIFVDAGASV-SYPSCGACLGMHSGV---LGPDDICISSSNRNFVGRMGDPSAQ 396
Query: 255 IYLASPYTAAASALTGRVADPREF 184
IYLASP T AASA+ G +ADPR +
Sbjct: 397 IYLASPATVAASAVEGFIADPRRY 420
[151][TOP]
>UniRef100_UPI00016C08CB 3-isopropylmalate dehydratase, large subunit n=1 Tax=Epulopiscium
sp. 'N.t. morphotype B' RepID=UPI00016C08CB
Length = 421
Score = 100 bits (249), Expect = 1e-19
Identities = 60/147 (40%), Positives = 85/147 (57%), Gaps = 2/147 (1%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALP 448
E ++KID+V IGSCT G+ ED A+ + G+KV V + TQ++++D A
Sbjct: 286 ELPEIKIDQVVIGSCTNGRLEDLRMASDILK--GKKVAKGVRAIVFPGTQQIYLDALAEG 343
Query: 447 VPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
+ +AGC ++P+CG CLGG A+ + VSTTNRNF GRMGH
Sbjct: 344 I--------VTNLVKAGC-VMSTPTCGPCLGGHMGILAK---GEKAVSTTNRNFVGRMGH 391
Query: 267 KEGQIYLASPYTAAASALTGRVADPRE 187
E ++YLASP AAASA+TG + +P +
Sbjct: 392 IESEVYLASPAVAAASAITGYITNPEK 418
[152][TOP]
>UniRef100_A5D4W1 3-isopropylmalate dehydratase large subunit n=1 Tax=Pelotomaculum
thermopropionicum SI RepID=A5D4W1_PELTS
Length = 420
Score = 100 bits (249), Expect = 1e-19
Identities = 60/147 (40%), Positives = 85/147 (57%), Gaps = 2/147 (1%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKV--KVPTFLVTATQKVWMDVYALP 448
E +++ID+V IGSCT G+ ED AA++ GRKV V + T K+++
Sbjct: 286 EAGNIEIDQVVIGSCTNGRMEDLREAARVLK--GRKVHKNVRLIIFPGTPKIYLQALR-- 341
Query: 447 VPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
+ + F EAG ++P+CG CLGG + AR + CV+TTNRNF GRMGH
Sbjct: 342 ------EGLIETFVEAG-GVVSTPTCGPCLGGHSGILAR---GERCVATTNRNFVGRMGH 391
Query: 267 KEGQIYLASPYTAAASALTGRVADPRE 187
E ++YL++P AAASA+ GR+ P E
Sbjct: 392 PESEVYLSNPAVAAASAVLGRIGGPWE 418
[153][TOP]
>UniRef100_Q46B45 3-isopropylmalate dehydratase, large subunit n=1 Tax=Methanosarcina
barkeri str. Fusaro RepID=Q46B45_METBF
Length = 413
Score = 100 bits (249), Expect = 1e-19
Identities = 64/144 (44%), Positives = 82/144 (56%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + ID+V+IG+CT G+ ED AA + G+KV V T ++ A++ +
Sbjct: 283 EVEGTHIDQVFIGTCTNGRLEDLEVAAAILK--GKKVAVRTIVIPASRTTLL-------- 332
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
A +I +AG T A+P CG CLG L E +VC+ST NRNF GRMG K
Sbjct: 333 AAIENGTMEILLKAGI-TLATPGCGPCLGAHQGV---LGEGEVCLSTANRNFKGRMG-KS 387
Query: 261 GQIYLASPYTAAASALTGRVADPR 190
G IYLASP TAAASAL G + DPR
Sbjct: 388 GFIYLASPATAAASALAGEITDPR 411
[154][TOP]
>UniRef100_Q8ZW41 3-isopropylmalate dehydratase large subunit n=1 Tax=Pyrobaculum
aerophilum RepID=LEUC_PYRAE
Length = 415
Score = 100 bits (249), Expect = 1e-19
Identities = 58/149 (38%), Positives = 85/149 (57%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RE + V++D+V+IGSCT G+ D AAK+ GR+VK + A+ +V+ L
Sbjct: 280 REVEGVEVDQVFIGSCTNGRLSDIAVAAKILK--GRRVKSRCIAIPASYEVFRRAMKLGY 337
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
+ EAGC +CG CLGG + +V V+T+NRNF GR+GH
Sbjct: 338 --------IDVLTEAGCVVTYG-TCGPCLGGH---FGVAGPGEVVVTTSNRNFRGRVGHP 385
Query: 264 EGQIYLASPYTAAASALTGRVADPREFLQ 178
+ +IYLA+P AAA+A G++ADPR +L+
Sbjct: 386 DAKIYLANPAVAAATAAEGKIADPRPYLR 414
[155][TOP]
>UniRef100_A8EQZ0 3-isopropylmalate dehydratase large subunit n=1 Tax=Arcobacter
butzleri RM4018 RepID=LEUC_ARCB4
Length = 426
Score = 100 bits (249), Expect = 1e-19
Identities = 60/143 (41%), Positives = 84/143 (58%), Gaps = 2/143 (1%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVPG 439
++K+D+V+IGSCT G+ DF AA++ AG+KV V L TQK+ + L
Sbjct: 296 NIKVDQVFIGSCTNGRLSDFKIAAEIL--AGQKVARHVRLILTPGTQKILREATKLGY-- 351
Query: 438 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 259
+AG ++P+CGACLGG L + +VC+STTNRNF GRMG +
Sbjct: 352 ------IDTLVDAGA-VVSNPTCGACLGGYMGI---LGDNEVCISTTNRNFVGRMGSRSS 401
Query: 258 QIYLASPYTAAASALTGRVADPR 190
+IYLA+ AAASA++G + DPR
Sbjct: 402 KIYLANSAVAAASAISGYITDPR 424
[156][TOP]
>UniRef100_A7VIP8 Putative uncharacterized protein n=1 Tax=Clostridium sp. L2-50
RepID=A7VIP8_9CLOT
Length = 441
Score = 100 bits (248), Expect = 1e-19
Identities = 58/145 (40%), Positives = 80/145 (55%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E D+KID+V IGSCT G+ D AA + V ++ TQ+V++
Sbjct: 306 EVGDIKIDQVVIGSCTNGRISDMRIAADIIKGRQVAPGVRVIVIPGTQEVYLQCIE---- 361
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
+ IF +AG ++P+CG CLGG A + VSTTNRNF GRMGH +
Sbjct: 362 ----EGLMTIFVKAGA-VVSTPTCGPCLGGHMGVMAA---GERAVSTTNRNFVGRMGHVD 413
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
++YLASP AAASA+TG+++ P E
Sbjct: 414 SEVYLASPAVAAASAITGKISSPEE 438
[157][TOP]
>UniRef100_Q2RG98 3-isopropylmalate dehydratase large subunit n=1 Tax=Moorella
thermoacetica ATCC 39073 RepID=LEUC_MOOTA
Length = 421
Score = 100 bits (248), Expect = 1e-19
Identities = 57/149 (38%), Positives = 84/149 (56%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
+E ++KID+V IGSCT G+ ED AA++ +V ++ TQ+++ A
Sbjct: 285 KEIGEIKIDQVVIGSCTNGRLEDLRVAAQILKGQKVHPEVRLIVIPGTQQIYAAALA--- 341
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
+ F EAG ++P+CG CLGG A+ + ++TTNRNF GRMGH
Sbjct: 342 -----EGLIATFIEAGAAV-STPTCGPCLGGHMGILAK---GERALATTNRNFVGRMGHP 392
Query: 264 EGQIYLASPYTAAASALTGRVADPREFLQ 178
E ++YLA P AAASA+ GR+A P E ++
Sbjct: 393 ESEVYLAGPAVAAASAVKGRIAAPEEVVK 421
[158][TOP]
>UniRef100_B3E9Z6 Homoaconitate hydratase family protein n=1 Tax=Geobacter lovleyi SZ
RepID=B3E9Z6_GEOLS
Length = 427
Score = 99.8 bits (247), Expect = 2e-19
Identities = 62/148 (41%), Positives = 86/148 (58%), Gaps = 1/148 (0%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E D ++D++Y+GSCT G+ ED AA++ V L AT K++ D
Sbjct: 294 EFTDSRVDQIYLGSCTNGRLEDLRIAAQILKGNKLAEHVRGILSPATPKIYRD------- 346
Query: 441 GAGGKTCAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
A + IF +AG C T + +CGACLG A + +VC STTNRNF GRMG K
Sbjct: 347 -AMKEGLIDIFLDAGFCVT--NSTCGACLGMSNGVLA---DGEVCASTTNRNFNGRMG-K 399
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
G ++L SP TAAA+A+ G++ADPR++L
Sbjct: 400 GGMVHLMSPATAAATAIEGKIADPRKYL 427
[159][TOP]
>UniRef100_A9BGP4 3-isopropylmalate dehydratase, large subunit n=1 Tax=Petrotoga
mobilis SJ95 RepID=A9BGP4_PETMO
Length = 419
Score = 99.8 bits (247), Expect = 2e-19
Identities = 57/148 (38%), Positives = 80/148 (54%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E K +KID+ IGSCT G+ ED AA + V + TQ ++M
Sbjct: 284 EAKRIKIDQSVIGSCTNGRIEDLRIAAHVLKGHKVNSDVRCIIFPGTQDIYMQALK---- 339
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
+ +IF EAG ++P+CG CLGG A+ + +STTNRNF GRMGH E
Sbjct: 340 ----EGLIEIFIEAGAAV-STPTCGPCLGGHMGVLAK---GEKAISTTNRNFVGRMGHPE 391
Query: 261 GQIYLASPYTAAASALTGRVADPREFLQ 178
++YL++P AAASA+TG + P E ++
Sbjct: 392 SEVYLSNPAVAAASAITGYITHPEEVIR 419
[160][TOP]
>UniRef100_C8QZ84 Homoaconitate hydratase family protein n=1 Tax=Desulfurivibrio
alkaliphilus AHT2 RepID=C8QZ84_9DELT
Length = 428
Score = 99.8 bits (247), Expect = 2e-19
Identities = 64/144 (44%), Positives = 84/144 (58%), Gaps = 1/144 (0%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGG 430
V +D++YIGSCT G+ ED AAK+ +V L AT KV+ A
Sbjct: 298 VPVDQIYIGSCTNGRIEDLREAAKVLKGRRIADQVRGILSPATPKVYNQ--------AME 349
Query: 429 KTCAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
+ +IF+EAG C T +P+CGACLG A E +VC STTNRNF GRMG K G +
Sbjct: 350 EGLLKIFQEAGFCVT--NPTCGACLGMSNGVLA---EGEVCASTTNRNFNGRMG-KGGIV 403
Query: 252 YLASPYTAAASALTGRVADPREFL 181
+L SP +AAA+A+ G++ DPR L
Sbjct: 404 HLMSPLSAAAAAVAGKITDPRPLL 427
[161][TOP]
>UniRef100_C5UT24 3-isopropylmalate dehydratase, large subunit n=1 Tax=Clostridium
botulinum E1 str. 'BoNT E Beluga' RepID=C5UT24_CLOBO
Length = 419
Score = 99.8 bits (247), Expect = 2e-19
Identities = 60/141 (42%), Positives = 81/141 (57%), Gaps = 2/141 (1%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVPGA 436
V ID+V IGSCT G+ D A + G+KVK + ++ TQK+++ +
Sbjct: 290 VDIDQVVIGSCTNGRISDLRIARDILK--GKKVKKGIRCIVIPGTQKIYLQALEEGI--- 344
Query: 435 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 256
+ EAG ++P+CG CLGG A+ + CVSTTNRNF GRMGH E +
Sbjct: 345 -----IKDLIEAGA-VVSTPTCGPCLGGHMGILAK---GERCVSTTNRNFVGRMGHVESE 395
Query: 255 IYLASPYTAAASALTGRVADP 193
+YLASP AAASALTG++ DP
Sbjct: 396 VYLASPAVAAASALTGKITDP 416
[162][TOP]
>UniRef100_A8SZ55 Putative uncharacterized protein n=1 Tax=Coprococcus eutactus ATCC
27759 RepID=A8SZ55_9FIRM
Length = 461
Score = 99.8 bits (247), Expect = 2e-19
Identities = 61/147 (41%), Positives = 83/147 (56%), Gaps = 2/147 (1%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALP 448
E D+KID+V IGSCT G+ D AA + GRKV V ++ TQ +++
Sbjct: 326 EVGDIKIDQVVIGSCTNGRISDMRIAADIIK--GRKVADGVRVIVIPGTQDIYLQCIE-- 381
Query: 447 VPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
+ IF +AG ++P+CG CLGG A + VSTTNRNF GRMGH
Sbjct: 382 ------EGLMTIFVKAGA-VVSTPTCGPCLGGHMGVMAA---GERAVSTTNRNFVGRMGH 431
Query: 267 KEGQIYLASPYTAAASALTGRVADPRE 187
+ ++YLASP AAASA+TG+++ P E
Sbjct: 432 VDSEVYLASPAVAAASAITGKISSPDE 458
[163][TOP]
>UniRef100_B4U7U5 3-isopropylmalate dehydratase large subunit n=1
Tax=Hydrogenobaculum sp. Y04AAS1 RepID=LEUC_HYDS0
Length = 424
Score = 99.8 bits (247), Expect = 2e-19
Identities = 60/147 (40%), Positives = 83/147 (56%), Gaps = 2/147 (1%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPT--FLVTATQKVWMDVYALP 448
E + ID+ +IGSCT G+ ED AA + G+KV T ++ A++ V++
Sbjct: 285 ESTHITIDQAFIGSCTNGRIEDLRIAASILK--GKKVHPYTRCVVIPASKNVYLQ----- 337
Query: 447 VPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
A + IF EAGC S +CG CLGG A+ + C+ST+NRNFPGRMGH
Sbjct: 338 ---ALHEGLVDIFIEAGCAVSTS-TCGPCLGGHMGILAK---GERCISTSNRNFPGRMGH 390
Query: 267 KEGQIYLASPYTAAASALTGRVADPRE 187
+ + YLA+P AASA+ GR+A P E
Sbjct: 391 PQSEAYLANPAVVAASAVLGRIAHPEE 417
[164][TOP]
>UniRef100_B2UYH6 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
botulinum E3 str. Alaska E43 RepID=LEUC_CLOBA
Length = 419
Score = 99.8 bits (247), Expect = 2e-19
Identities = 60/141 (42%), Positives = 81/141 (57%), Gaps = 2/141 (1%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVPGA 436
V ID+V IGSCT G+ D A + G+KVK + ++ TQK+++ +
Sbjct: 290 VNIDQVVIGSCTNGRISDLRIARGILK--GKKVKKGIRCIVIPGTQKIYLQALEEGI--- 344
Query: 435 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 256
+ EAG ++P+CG CLGG A+ + CVSTTNRNF GRMGH E +
Sbjct: 345 -----IKDLIEAGA-VVSTPTCGPCLGGHMGILAK---GERCVSTTNRNFVGRMGHVESE 395
Query: 255 IYLASPYTAAASALTGRVADP 193
+YLASP AAASALTG++ DP
Sbjct: 396 VYLASPAVAAASALTGKITDP 416
[165][TOP]
>UniRef100_Q24XT4 3-isopropylmalate dehydratase large subunit n=2
Tax=Desulfitobacterium hafniense RepID=LEUC_DESHY
Length = 421
Score = 99.4 bits (246), Expect = 2e-19
Identities = 62/154 (40%), Positives = 83/154 (53%), Gaps = 7/154 (4%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E K +KID+V IGSCT G+ ED AA++ QKV DV + +P
Sbjct: 287 EGKGIKIDQVVIGSCTNGRLEDMQVAAQILKG---------------QKVHGDVRLIVIP 331
Query: 441 G-------AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFP 283
G A + IF +AG ++P+CG CLGG A+ + +STTNRNF
Sbjct: 332 GTQDIYKQAMQEGLIDIFIDAGA-VVSTPTCGPCLGGYMGILAK---GERALSTTNRNFV 387
Query: 282 GRMGHKEGQIYLASPYTAAASALTGRVADPREFL 181
GRMGH E ++YL+ P AAASA+TG ++ P E L
Sbjct: 388 GRMGHPESEVYLSGPAVAAASAVTGEISHPEEVL 421
[166][TOP]
>UniRef100_C1TNL5 3-isopropylmalate dehydratase, large subunit n=1
Tax=Dethiosulfovibrio peptidovorans DSM 11002
RepID=C1TNL5_9BACT
Length = 419
Score = 99.4 bits (246), Expect = 2e-19
Identities = 58/142 (40%), Positives = 79/142 (55%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
D +I +V+IGSCT G+ ED AAA + V ++ A+ +V+
Sbjct: 287 DTEIQQVFIGSCTNGRLEDMAAAASVLEGKKVHPSVRCIVIPASYEVYNACLE------- 339
Query: 432 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
K + F EAG +P+CG CLGG A E + CVST+NRNF GRMGH + ++
Sbjct: 340 -KGYIRTFTEAGAAV-CTPTCGPCLGGHMGILA---EGERCVSTSNRNFVGRMGHPKSEV 394
Query: 252 YLASPYTAAASALTGRVADPRE 187
YLASP TAA SA+ G +ADP +
Sbjct: 395 YLASPVTAAWSAVKGHIADPAQ 416
[167][TOP]
>UniRef100_A8RZ58 Putative uncharacterized protein n=1 Tax=Clostridium bolteae ATCC
BAA-613 RepID=A8RZ58_9CLOT
Length = 420
Score = 99.4 bits (246), Expect = 2e-19
Identities = 59/142 (41%), Positives = 84/142 (59%), Gaps = 2/142 (1%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVPG 439
+VK+D+ IGSCT G+ ED AA++ GRK+ V ++ ATQ +++
Sbjct: 289 EVKVDQAVIGSCTNGRIEDMRIAAEVLK--GRKIAKGVRCIVIPATQSIYLQ-------- 338
Query: 438 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 259
A + +IF EAG ++P+CG CLGG A + C+STTNRNF GRMGH +
Sbjct: 339 AMKEGLLEIFIEAGA-VVSTPTCGPCLGGYMGILAA---GERCISTTNRNFVGRMGHVDS 394
Query: 258 QIYLASPYTAAASALTGRVADP 193
++YLASP AAASA+ G++ P
Sbjct: 395 EVYLASPAVAAASAVAGKIICP 416
[168][TOP]
>UniRef100_A1RVH3 3-isopropylmalate dehydratase large subunit n=1 Tax=Pyrobaculum
islandicum DSM 4184 RepID=LEUC_PYRIL
Length = 414
Score = 99.4 bits (246), Expect = 2e-19
Identities = 57/148 (38%), Positives = 83/148 (56%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RE + V++D+V+IGSCT G+ DF AA++ +VK + A+ ++ L
Sbjct: 280 REVEGVEVDQVFIGSCTNGRLSDFEIAARILRRG--RVKSRCIAIPASYTIFRKALELGY 337
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
I +AGC +CG CLGG + +V VST+NRNF GRMGH
Sbjct: 338 --------IDILTKAGCVVTYG-TCGPCLGGH---FGVAGPGEVVVSTSNRNFKGRMGHP 385
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
+ ++YLA+P TAAA+AL G++ DPR +L
Sbjct: 386 DSKVYLANPATAAAAALEGKIVDPRPYL 413
[169][TOP]
>UniRef100_B2KBD7 3-isopropylmalate dehydratase large subunit n=1 Tax=Elusimicrobium
minutum Pei191 RepID=LEUC_ELUMP
Length = 418
Score = 99.4 bits (246), Expect = 2e-19
Identities = 57/148 (38%), Positives = 85/148 (57%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E KD+K+++V+IG+CT G+ ED AA++ TF+ A++ V +
Sbjct: 283 ELKDIKVNQVFIGTCTNGRIEDLRIAAEILKDKKVNPGTRTFITPASRDVML-------- 334
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
A + +IF +AG +P CG C+G L + +VC++T NRNF GRMG+ +
Sbjct: 335 AALKEGLIEIFVKAGASVQ-TPGCGPCVGVHGGI---LGDGEVCLATQNRNFQGRMGNTK 390
Query: 261 GQIYLASPYTAAASALTGRVADPREFLQ 178
G IYL+SP AA SAL G ++DPRE L+
Sbjct: 391 GFIYLSSPAVAAYSALKGYISDPREILK 418
[170][TOP]
>UniRef100_B2TIQ9 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
botulinum B str. Eklund 17B RepID=LEUC_CLOBB
Length = 419
Score = 99.4 bits (246), Expect = 2e-19
Identities = 59/142 (41%), Positives = 81/142 (57%), Gaps = 2/142 (1%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVPG 439
D+ ID+V IGSCT G+ D A + G+KVK + ++ TQ +++ +
Sbjct: 289 DIDIDQVVIGSCTNGRISDLRIARDILK--GKKVKKGIRCIVIPGTQNIYLQALEEGI-- 344
Query: 438 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 259
+ EAG ++P+CG CLGG A+ + CVSTTNRNF GRMGH E
Sbjct: 345 ------IKDLIEAGV-VVSTPTCGPCLGGHMGILAK---GERCVSTTNRNFVGRMGHVES 394
Query: 258 QIYLASPYTAAASALTGRVADP 193
++YLASP AAASALTG++ DP
Sbjct: 395 EVYLASPAVAAASALTGKITDP 416
[171][TOP]
>UniRef100_A7HZP6 3-isopropylmalate dehydratase large subunit n=1 Tax=Campylobacter
hominis ATCC BAA-381 RepID=LEUC_CAMHC
Length = 419
Score = 99.4 bits (246), Expect = 2e-19
Identities = 60/143 (41%), Positives = 84/143 (58%), Gaps = 2/143 (1%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVT--ATQKVWMDVYALPVPG 439
++KID+ +IGSCT G+ D AA++ G+KV T L+ ATQK++
Sbjct: 290 ELKIDQAFIGSCTNGRLSDLRIAAEILK--GKKVAKKTRLIITPATQKIYK--------A 339
Query: 438 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 259
A + IF +AG ++P+CGACLGG L + CVSTTNRNF GRMG +
Sbjct: 340 AEHEGLIDIFIDAGA-VVSNPTCGACLGGYMGI---LGANERCVSTTNRNFVGRMGDRTS 395
Query: 258 QIYLASPYTAAASALTGRVADPR 190
++YLA+ AASA+TG++ DPR
Sbjct: 396 EVYLANSAVVAASAITGKITDPR 418
[172][TOP]
>UniRef100_Q8U2A1 3-isopropylmalate dehydratase large subunit 1 n=1 Tax=Pyrococcus
furiosus RepID=LEUC1_PYRFU
Length = 424
Score = 99.4 bits (246), Expect = 2e-19
Identities = 63/150 (42%), Positives = 83/150 (55%), Gaps = 5/150 (3%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPG-- 439
++KID+V IGSCT G+ ED AA++ G+KV W+ + LP
Sbjct: 292 NIKIDQVVIGSCTNGRLEDLRMAAEVLE--GQKVAP-----------WVRLIILPCSPTV 338
Query: 438 ---AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
A + +IF EAG P+CG CLGG A + VSTTNRNF GRMGH
Sbjct: 339 YFKAMKEGLLEIFLEAGA-VIGPPTCGPCLGGHMGILA---SGERAVSTTNRNFVGRMGH 394
Query: 267 KEGQIYLASPYTAAASALTGRVADPREFLQ 178
+ ++YLASPY AAASA+ GR+A P E ++
Sbjct: 395 PKSEVYLASPYVAAASAILGRIASPEEVVK 424
[173][TOP]
>UniRef100_Q9UZ07 3-isopropylmalate dehydratase large subunit 1 n=1 Tax=Pyrococcus
abyssi RepID=LEUC1_PYRAB
Length = 423
Score = 99.4 bits (246), Expect = 2e-19
Identities = 61/150 (40%), Positives = 84/150 (56%), Gaps = 5/150 (3%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPG-- 439
++KID+V+IGSCT G+ ED AA++ G+KV W+ + +P
Sbjct: 291 NIKIDQVFIGSCTNGRIEDLRMAAEILE--GQKVAK-----------WVRLIVIPCSPTV 337
Query: 438 ---AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
A + +IF EAG P+CG CLGG A + VSTTNRNF GRMGH
Sbjct: 338 YWKALKEGLIEIFLEAGA-VIGPPTCGPCLGGHMGVLA---SGERAVSTTNRNFVGRMGH 393
Query: 267 KEGQIYLASPYTAAASALTGRVADPREFLQ 178
+ ++YLA+PY AAASA+ GR+A P E ++
Sbjct: 394 PKSEVYLANPYVAAASAVLGRIASPEEVVK 423
[174][TOP]
>UniRef100_A6TSE5 3-isopropylmalate dehydratase n=1 Tax=Alkaliphilus metalliredigens
QYMF RepID=A6TSE5_ALKMQ
Length = 425
Score = 99.0 bits (245), Expect = 3e-19
Identities = 62/155 (40%), Positives = 86/155 (55%), Gaps = 9/155 (5%)
Frame = -3
Query: 615 KDVKIDRVYIGSCTGGKTEDFMAAAKLF-----HAAGRKVKVPT---FLVTATQKVWMDV 460
K+VK+D+V+IG+CTGG+ ED AA++ H R + +P L A +K +M
Sbjct: 284 KEVKVDQVFIGTCTGGRLEDIEVAARIIKNNKIHRDTRLLVIPASKEVLEKAIEKGYMTT 343
Query: 459 YALPVPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEP-QVCVSTTNRNFP 283
+AG T SP CG CLG T+ L P +VC +T++RNFP
Sbjct: 344 LI----------------KAGA-TFTSPGCGPCLG----THQGLLAPGEVCATTSSRNFP 382
Query: 282 GRMGHKEGQIYLASPYTAAASALTGRVADPREFLQ 178
GRMG E IYL SP TAAA A+TG++ DPR +++
Sbjct: 383 GRMGSTEADIYLVSPATAAAIAITGKITDPRGYIE 417
[175][TOP]
>UniRef100_C5ZZ28 3-isopropylmalate dehydratase, large subunit n=1 Tax=Helicobacter
canadensis MIT 98-5491 RepID=C5ZZ28_9HELI
Length = 421
Score = 99.0 bits (245), Expect = 3e-19
Identities = 56/142 (39%), Positives = 81/142 (57%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
D+KID+V+IGSCT G+ D A+++ V + TQ+++ + Y L
Sbjct: 292 DLKIDQVFIGSCTNGRLADLKIASEILKGKKVHKDVRLIVTPGTQQIYKEAYQLGY---- 347
Query: 432 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
I E+G ++P+CGACLGG L + + CVSTTNRNF GRMG + ++
Sbjct: 348 ----IDILLESGA-LISNPTCGACLGGYMGI---LGDNERCVSTTNRNFVGRMGARSSEV 399
Query: 252 YLASPYTAAASALTGRVADPRE 187
YLA+ AA SA+ G++ADPRE
Sbjct: 400 YLANSAVAAMSAIKGQIADPRE 421
[176][TOP]
>UniRef100_C5F2A2 3-isopropylmalate dehydratase large subunit n=1 Tax=Helicobacter
pullorum MIT 98-5489 RepID=C5F2A2_9HELI
Length = 422
Score = 99.0 bits (245), Expect = 3e-19
Identities = 56/142 (39%), Positives = 80/142 (56%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
D+KID+V+IGSCT G+ D A+++ V + TQ ++ + + L
Sbjct: 292 DLKIDQVFIGSCTNGRLSDLKIASEILKGKKVHQDVRLIITPGTQNIYKEAHKLGY---- 347
Query: 432 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
I EAG ++P+CGACLGG L + + CVSTTNRNF GRMG + ++
Sbjct: 348 ----IDILLEAGA-LISNPTCGACLGGYMGI---LGDNERCVSTTNRNFVGRMGARNSEV 399
Query: 252 YLASPYTAAASALTGRVADPRE 187
YLA+ AA SA+ G++ADPRE
Sbjct: 400 YLANSAVAAISAIKGKIADPRE 421
[177][TOP]
>UniRef100_C5EK99 3-isopropylmalate dehydratase n=1 Tax=Clostridiales bacterium
1_7_47FAA RepID=C5EK99_9FIRM
Length = 419
Score = 99.0 bits (245), Expect = 3e-19
Identities = 60/146 (41%), Positives = 82/146 (56%), Gaps = 2/146 (1%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVT--ATQKVWMDVYALPVPG 439
++K+++ YIGSCTGG+ ED AA++ GR + + LV A+ +V +
Sbjct: 288 EMKLNQGYIGSCTGGREEDIAVAARI--VKGRHIPPYSRLVVVPASSEVMLSCME----- 340
Query: 438 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 259
K Q AG T +P CGACLG A + C+S+TNRNFPGRMG +
Sbjct: 341 ---KGYIQDLMNAGA-TITTPGCGACLGAHEGIIA---PGETCISSTNRNFPGRMGSNQA 393
Query: 258 QIYLASPYTAAASALTGRVADPREFL 181
IYLASP T AAS + GR+ DPR++L
Sbjct: 394 SIYLASPATVAASIINGRITDPRDYL 419
[178][TOP]
>UniRef100_Q97EE0 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
acetobutylicum RepID=LEUC_CLOAB
Length = 422
Score = 99.0 bits (245), Expect = 3e-19
Identities = 56/144 (38%), Positives = 80/144 (55%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
+V +D+V IGSCT G+ ED AA + K + + TQ ++++ A
Sbjct: 291 EVNVDQVVIGSCTNGRMEDLRIAASILKGKKIKKGIRLIVFPGTQNIYLE--------AM 342
Query: 432 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
+ + F EAG ++P+CG CLGG A E + +STTNRNF GRMGH + ++
Sbjct: 343 EEGLVRTFIEAG-GIVSTPTCGPCLGGHMGILA---EGERAISTTNRNFVGRMGHPKSEV 398
Query: 252 YLASPYTAAASALTGRVADPREFL 181
YLASP AAASA+ G++ P E L
Sbjct: 399 YLASPAVAAASAIAGKIVSPEEVL 422
[179][TOP]
>UniRef100_B9L0Y1 3-isopropylmalate dehydratase, large subunit n=1
Tax=Thermomicrobium roseum DSM 5159 RepID=B9L0Y1_THERP
Length = 422
Score = 98.6 bits (244), Expect = 4e-19
Identities = 61/145 (42%), Positives = 80/145 (55%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E +D+ ID+V IGSCT G+ D AA++ +V ++ +Q+V
Sbjct: 288 EVRDLPIDQVVIGSCTNGRLSDLRIAAEILKGRQVHPRVRCIVIPGSQEV--------AK 339
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
A + IF EAG S +CG CLGG A+ + CVSTTNRNF GRMGH+E
Sbjct: 340 QATREGLVDIFLEAGAVFSVS-TCGPCLGGYMGVLAK---GERCVSTTNRNFRGRMGHRE 395
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
++ LASP AAASA+ GRVA P E
Sbjct: 396 SEVILASPAVAAASAVLGRVASPFE 420
[180][TOP]
>UniRef100_C9RAX0 3-isopropylmalate dehydratase, large subunit n=1 Tax=Ammonifex
degensii KC4 RepID=C9RAX0_9THEO
Length = 421
Score = 98.6 bits (244), Expect = 4e-19
Identities = 61/150 (40%), Positives = 86/150 (57%), Gaps = 2/150 (1%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALP 448
E + ID+V IGSCT G+ ED AA++ G+KV V ++ TQ+++
Sbjct: 285 EVTHITIDQVVIGSCTNGRLEDLRVAAQVLK--GKKVHPYVRLIVIPGTQEIYRQALR-- 340
Query: 447 VPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
+ +IF EAG ++P+CG CLGG A+ + V+TTNRNF GRMGH
Sbjct: 341 ------EGLIEIFLEAG-GAVSTPTCGPCLGGHMGVLAK---GERAVATTNRNFVGRMGH 390
Query: 267 KEGQIYLASPYTAAASALTGRVADPREFLQ 178
E ++YLASP AAASA+ GR+A P E ++
Sbjct: 391 PESEVYLASPAVAAASAVLGRLAHPDEVVK 420
[181][TOP]
>UniRef100_B0A9M7 Putative uncharacterized protein n=1 Tax=Clostridium bartlettii DSM
16795 RepID=B0A9M7_9CLOT
Length = 429
Score = 98.6 bits (244), Expect = 4e-19
Identities = 60/145 (41%), Positives = 81/145 (55%), Gaps = 2/145 (1%)
Frame = -3
Query: 615 KDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVP 442
+D+KID+V IGSCT G+ ED AA++ G+KV V + TQ ++++
Sbjct: 293 EDIKIDQVVIGSCTNGRIEDMRIAAEIMR--GKKVADDVRCIVFPGTQAIYLEAIEK--- 347
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
G + A TP +CG CLGG A + VSTTNRNF GRMGH E
Sbjct: 348 ---GYITDMVLAGAAISTP---TCGPCLGGHMGILAA---GERAVSTTNRNFVGRMGHTE 398
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
++YLASP AAASA+TG+++ P E
Sbjct: 399 SEVYLASPAVAAASAITGKISSPSE 423
[182][TOP]
>UniRef100_A7ZFP0 3-isopropylmalate dehydratase large subunit n=1 Tax=Campylobacter
concisus 13826 RepID=LEUC_CAMC1
Length = 421
Score = 98.6 bits (244), Expect = 4e-19
Identities = 61/144 (42%), Positives = 83/144 (57%), Gaps = 2/144 (1%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVT--ATQKVWMDVYALPVPG 439
D+ ID+ +IGSCT G+ D AA++ G+KV T L+ ATQK+
Sbjct: 291 DLAIDQAFIGSCTNGRLSDLRIAAQILK--GKKVARKTRLIITPATQKI--------ARA 340
Query: 438 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 259
A + IF EAG ++P+CGACLGG L + C+STTNRNF GRMG +
Sbjct: 341 AEKEGLIDIFIEAGA-VVSNPTCGACLGGYMGI---LGANERCISTTNRNFVGRMGDRTS 396
Query: 258 QIYLASPYTAAASALTGRVADPRE 187
+IYLA+ AASA+ G++ADPR+
Sbjct: 397 EIYLANSAVVAASAIAGKIADPRD 420
[183][TOP]
>UniRef100_Q8TLF1 3-isopropylmalate dehydratase large subunit 1 n=1
Tax=Methanosarcina acetivorans RepID=LEUC1_METAC
Length = 424
Score = 98.6 bits (244), Expect = 4e-19
Identities = 63/144 (43%), Positives = 82/144 (56%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + +D+V+IG+CT G+ ED AA + G++V V T ++ A++ +
Sbjct: 294 EVEGTHVDQVFIGTCTNGRLEDLEVAAAVLK--GKQVAVRTIVIPASRTTLL-------- 343
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
A + +AG T A+P CG CLG L E +VCVST NRNF GRMG K
Sbjct: 344 AAIENGTMETLLKAGV-TLATPGCGPCLGAHQGV---LGEGEVCVSTANRNFKGRMG-KG 398
Query: 261 GQIYLASPYTAAASALTGRVADPR 190
G IYLASP TAAASALTG + DPR
Sbjct: 399 GFIYLASPATAAASALTGEITDPR 422
[184][TOP]
>UniRef100_C9KK15 Homoaconitate hydratase n=1 Tax=Mitsuokella multacida DSM 20544
RepID=C9KK15_9FIRM
Length = 423
Score = 98.2 bits (243), Expect = 5e-19
Identities = 62/143 (43%), Positives = 82/143 (57%), Gaps = 2/143 (1%)
Frame = -3
Query: 603 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPT--FLVTATQKVWMDVYALPVPGAGG 430
+D+ Y+GSCTGG+TEDF AAK+ AG+ + T +V A++ V + A
Sbjct: 288 VDQAYLGSCTGGRTEDFAVAAKIL--AGQHIPAGTRMVMVPASKAVLAECLA-------- 337
Query: 429 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 250
K Q AG AS C ACLG A +VC+S+TNRNFPGRMG +G+IY
Sbjct: 338 KGYIQTLLAAGATLTAS-GCAACLGIHQGLLAA---DEVCLSSTNRNFPGRMGSVKGRIY 393
Query: 249 LASPYTAAASALTGRVADPREFL 181
L SP + AA+A G V DPR++L
Sbjct: 394 LGSPASVAAAARNGVVTDPRQYL 416
[185][TOP]
>UniRef100_B0MLF2 Putative uncharacterized protein n=1 Tax=Eubacterium siraeum DSM
15702 RepID=B0MLF2_9FIRM
Length = 418
Score = 98.2 bits (243), Expect = 5e-19
Identities = 55/138 (39%), Positives = 78/138 (56%)
Frame = -3
Query: 615 KDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGA 436
+D+KID+ IGSCT G+ D AA++ V ++ TQKV++
Sbjct: 289 EDIKIDQAVIGSCTNGRISDMRIAAEILKGKHIAKGVRCIVIPGTQKVYLQCIK------ 342
Query: 435 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 256
+ A+IF AGC ++P+CG CLGG A + +STTNRNF GRMGH + +
Sbjct: 343 --EGLAEIFVNAGC-VLSTPTCGPCLGGHMGILAA---GERAISTTNRNFVGRMGHVDSE 396
Query: 255 IYLASPYTAAASALTGRV 202
+YLASP AAASA+ G++
Sbjct: 397 VYLASPAVAAASAIAGKI 414
[186][TOP]
>UniRef100_A7VNU8 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
RepID=A7VNU8_9CLOT
Length = 428
Score = 98.2 bits (243), Expect = 5e-19
Identities = 59/141 (41%), Positives = 77/141 (54%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGG 430
VKID+V IGSCT G+ D AA L V + TQ +++D A
Sbjct: 290 VKIDQVVIGSCTNGRLSDLRIAANLLKGKKVAKNVRCIVFPGTQTIYLD--------AMR 341
Query: 429 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 250
+ + F +AG ++P+CG CLGG A + VSTTNRNF GRMGH + ++Y
Sbjct: 342 EGLVEAFIQAGA-VVSTPTCGPCLGGHMGILAA---GERAVSTTNRNFVGRMGHVDSEVY 397
Query: 249 LASPYTAAASALTGRVADPRE 187
LASP AAASA+TG + DP E
Sbjct: 398 LASPAVAAASAVTGYITDPAE 418
[187][TOP]
>UniRef100_A1HRB9 Homoaconitate hydratase family protein n=1 Tax=Thermosinus
carboxydivorans Nor1 RepID=A1HRB9_9FIRM
Length = 420
Score = 98.2 bits (243), Expect = 5e-19
Identities = 62/143 (43%), Positives = 79/143 (55%), Gaps = 2/143 (1%)
Frame = -3
Query: 603 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVPGAGG 430
I + YIGSCTGG+ D AAA++ GRKV V + A+ ++W A
Sbjct: 292 IHQAYIGSCTGGRYNDLAAAARVLK--GRKVANGVRLLVSPASHEIWRQ--------AAA 341
Query: 429 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 250
I EAG A P+CG C+G + A + + C+S+TNRNF GRMG K IY
Sbjct: 342 DGILSILAEAGAIILA-PTCGVCVGLHSGLLA---DGEYCISSTNRNFIGRMGSKNAGIY 397
Query: 249 LASPYTAAASALTGRVADPREFL 181
LASP AASA+TG + DPREFL
Sbjct: 398 LASPMAVAASAITGVITDPREFL 420
[188][TOP]
>UniRef100_B5YKE0 3-isopropylmalate dehydratase large subunit n=1
Tax=Thermodesulfovibrio yellowstonii DSM 11347
RepID=LEUC_THEYD
Length = 421
Score = 98.2 bits (243), Expect = 5e-19
Identities = 59/147 (40%), Positives = 83/147 (56%), Gaps = 2/147 (1%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKV--KVPTFLVTATQKVWMDVYALP 448
E +KID+V IGSCT G+ ED AA + GRKV +V ++ ATQK++M
Sbjct: 286 ELSHIKIDQVVIGSCTNGRLEDLREAAMVLK--GRKVHPEVRMIIIPATQKIYMQALK-- 341
Query: 447 VPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
+ +IF +A + P+CG CLGG A+ + ++TTNRNF GRMGH
Sbjct: 342 ------EGLIEIFIDAQA-VVSPPTCGPCLGGHMGILAK---GERAIATTNRNFVGRMGH 391
Query: 267 KEGQIYLASPYTAAASALTGRVADPRE 187
E ++YL++P AAAS + GR+ P E
Sbjct: 392 PESEVYLSNPAVAAASGVLGRIGTPEE 418
[189][TOP]
>UniRef100_B8CX22 3-isopropylmalate dehydratase large subunit n=1 Tax=Halothermothrix
orenii H 168 RepID=LEUC_HALOH
Length = 420
Score = 98.2 bits (243), Expect = 5e-19
Identities = 57/144 (39%), Positives = 78/144 (54%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
D+KID+ IGSCT G+ ED AA + V ++ TQ ++
Sbjct: 289 DIKIDQAVIGSCTNGRMEDLRIAAGILKEKQVHHDVRCIVIPGTQDIYKQALK------- 341
Query: 432 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
+ +IF EAG ++P+CG CLGG AR + ++TTNRNF GRMGH E ++
Sbjct: 342 -EGLIEIFIEAGAAV-STPTCGPCLGGHMGILAR---GEKAIATTNRNFVGRMGHPESEV 396
Query: 252 YLASPYTAAASALTGRVADPREFL 181
YLA+P AAASA+ G +A P E L
Sbjct: 397 YLANPAVAAASAIKGYIAHPEEVL 420
[190][TOP]
>UniRef100_B1H0A6 3-isopropylmalate dehydratase large subunit n=1 Tax=uncultured
Termite group 1 bacterium phylotype Rs-D17
RepID=LEUC_UNCTG
Length = 420
Score = 97.8 bits (242), Expect = 6e-19
Identities = 64/148 (43%), Positives = 83/148 (56%), Gaps = 5/148 (3%)
Frame = -3
Query: 615 KDVK---IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYAL 451
KD+K ID+V IGSCT G+ ED AA + G+KV V T ++ AT +V+
Sbjct: 285 KDIKKTYIDQVVIGSCTNGRIEDLRVAASIIKK-GKKVNSNVRTLIIPATPEVYSQ---- 339
Query: 450 PVPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMG 271
A + +IF +AG A P+CG CLGG A + C STTNRNF GRMG
Sbjct: 340 ----ALDEGLLRIFMDAGAIISA-PTCGPCLGGHMGILA---SGEKCASTTNRNFRGRMG 391
Query: 270 HKEGQIYLASPYTAAASALTGRVADPRE 187
H E Q++L +P AAASA+ G +A P E
Sbjct: 392 HVESQLFLVNPAVAAASAIKGYIASPDE 419
[191][TOP]
>UniRef100_Q2KVM0 3-isopropylmalate dehydratase large subunit n=1 Tax=Bordetella
avium 197N RepID=Q2KVM0_BORA1
Length = 422
Score = 97.4 bits (241), Expect = 8e-19
Identities = 60/144 (41%), Positives = 76/144 (52%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
DV + YIG+CTG K ED AAA + + + A+Q+ A V
Sbjct: 291 DVPLQVAYIGACTGAKLEDLRAAASVLRGRRLAAGMRLMVAPASQQDQRQAEAEGV---- 346
Query: 432 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
Q EAG D A+ SCGAC G + + +STT RNF GRMG + Q+
Sbjct: 347 ----MQALREAGADVLAT-SCGACAGYGGS----IPDGASVISTTARNFKGRMGSETAQV 397
Query: 252 YLASPYTAAASALTGRVADPREFL 181
YLASPYT AASA+ GR+ADPREF+
Sbjct: 398 YLASPYTVAASAVAGRIADPREFM 421
[192][TOP]
>UniRef100_C5EHB8 3-isopropylmalate dehydratase n=1 Tax=Clostridiales bacterium
1_7_47FAA RepID=C5EHB8_9FIRM
Length = 438
Score = 97.4 bits (241), Expect = 8e-19
Identities = 66/147 (44%), Positives = 81/147 (55%), Gaps = 2/147 (1%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALP 448
E K KID VYIGSCT G ED AA++ G+KV + +V AT KV+ D A
Sbjct: 292 EVKGTKIDEVYIGSCTNGSLEDMRIAAEIME--GKKVPDDLRVIVVPATNKVFKDAIA-- 347
Query: 447 VPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
AG + F EAGC + P CG C G P Y + + + +ST NRNF GR G
Sbjct: 348 ---AG---YIRTFIEAGC-VISHPCCGLCCGMP---YGLMYDDERILSTANRNFIGRQGT 397
Query: 267 KEGQIYLASPYTAAASALTGRVADPRE 187
K+ YL+SP AAA+AL G V DPRE
Sbjct: 398 KKTLSYLSSPAVAAATALAGVVTDPRE 424
[193][TOP]
>UniRef100_A6DDD6 3-ISOPROPYLMALATE DEHYDRATASE, LARGE SUBUNIT n=1 Tax=Caminibacter
mediatlanticus TB-2 RepID=A6DDD6_9PROT
Length = 425
Score = 97.4 bits (241), Expect = 8e-19
Identities = 56/142 (39%), Positives = 79/142 (55%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
D++I +VYIGSCT G D AA + +V + ATQ+++ A
Sbjct: 295 DIEIHQVYIGSCTNGTLSDLRTAANILKGKRVHKRVRLIVTPATQRIYKQ--------AE 346
Query: 432 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
+ +AG A+P+CGACLGG L + + CV+TTNRNF GRMG + +I
Sbjct: 347 HEGIIDTLIDAGA-VVANPTCGACLGGYMGI---LGDGERCVATTNRNFRGRMGSRSSEI 402
Query: 252 YLASPYTAAASALTGRVADPRE 187
YL++ AAASA+ G++ADPRE
Sbjct: 403 YLSNSAVAAASAIAGKIADPRE 424
[194][TOP]
>UniRef100_B5IEF0 Homoaconitate hydratase family protein n=1 Tax=Aciduliprofundum
boonei T469 RepID=B5IEF0_9EURY
Length = 418
Score = 97.4 bits (241), Expect = 8e-19
Identities = 55/147 (37%), Positives = 80/147 (54%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
+ + +++++V++G+CT G+ ED AA++ V + A+ VW +
Sbjct: 284 KAEGIEVNQVFLGTCTNGRVEDLEVAARILKGNKVNKNVRMLVFPASWDVWRE------- 336
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
A K + EAG +P CG CLG A A + + C+ST NRNF GRMG+
Sbjct: 337 -ANEKGILRTLAEAGA-VIMNPGCGPCLGAHAGVLA---DGEKCLSTANRNFKGRMGNPN 391
Query: 261 GQIYLASPYTAAASALTGRVADPREFL 181
+IYL SP TAAA+AL G +ADPRE L
Sbjct: 392 AEIYLGSPATAAATALKGYIADPREVL 418
[195][TOP]
>UniRef100_B2V844 3-isopropylmalate dehydratase large subunit n=1
Tax=Sulfurihydrogenibium sp. YO3AOP1 RepID=LEUC_SULSY
Length = 431
Score = 97.4 bits (241), Expect = 8e-19
Identities = 57/145 (39%), Positives = 81/145 (55%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E ID+V+IGSCT G+ D AA + + +V ++ A+ +++
Sbjct: 286 EVAGTHIDQVFIGSCTNGRLSDLRIAAAILKSKKVHPEVRCIVIPASDQIYKQ------- 338
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
A + +I +AGC S +CG CLGG A E +VC+ST+NRNF GRMGH +
Sbjct: 339 -ALHEGIIEILADAGCLISTS-TCGPCLGGHMGILA---EGEVCLSTSNRNFVGRMGHPK 393
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
Q+YL+SP AAASA+ GR+A P E
Sbjct: 394 SQVYLSSPAVAAASAVLGRIAHPDE 418
[196][TOP]
>UniRef100_A4XJ48 3-isopropylmalate dehydratase large subunit n=1
Tax=Caldicellulosiruptor saccharolyticus DSM 8903
RepID=LEUC_CALS8
Length = 429
Score = 97.4 bits (241), Expect = 8e-19
Identities = 59/143 (41%), Positives = 81/143 (56%), Gaps = 2/143 (1%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVPGA 436
+ ID+V IGSCT G+ ED AAK+ GRKVK + + ATQ ++
Sbjct: 293 IYIDQVVIGSCTNGRIEDLRIAAKILK--GRKVKKGLRCIIFPATQNIYKQALK------ 344
Query: 435 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 256
+ +IF +AGC ++P+CG CLGG A E + ++TTNRNF GRMGH +
Sbjct: 345 --EGLIEIFIDAGC-VVSTPTCGPCLGGHMGILA---EGERALATTNRNFVGRMGHPNSE 398
Query: 255 IYLASPYTAAASALTGRVADPRE 187
+YL+SP AAASA+ G + P E
Sbjct: 399 VYLSSPAIAAASAVLGYIGSPEE 421
[197][TOP]
>UniRef100_C1DUH4 3-isopropylmalate dehydratase, large subunit n=1
Tax=Sulfurihydrogenibium azorense Az-Fu1
RepID=C1DUH4_SULAA
Length = 431
Score = 97.1 bits (240), Expect = 1e-18
Identities = 57/145 (39%), Positives = 80/145 (55%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E ID+V+IGSCT G+ D AA + +V ++ A+ +++
Sbjct: 286 EVAGTHIDQVFIGSCTNGRLSDLRIAAAILKGKKVHPEVRCIVIPASDQIYKQ------- 338
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
A + +I +AGC S +CG CLGG A E +VC+ST+NRNF GRMGH +
Sbjct: 339 -ALHEGIIEILADAGCLISTS-TCGPCLGGHMGILA---EGEVCLSTSNRNFVGRMGHPK 393
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
Q+YL+SP AAASA+ GR+A P E
Sbjct: 394 SQVYLSSPAVAAASAVLGRIAHPDE 418
[198][TOP]
>UniRef100_B1I1Y2 3-isopropylmalate dehydratase, large subunit n=1 Tax=Candidatus
Desulforudis audaxviator MP104C RepID=B1I1Y2_DESAP
Length = 420
Score = 97.1 bits (240), Expect = 1e-18
Identities = 58/145 (40%), Positives = 80/145 (55%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E V+ID+V IGSCT G+ ED AA++ V ++ TQ+++
Sbjct: 286 EAGRVEIDQVVIGSCTNGRMEDLRLAARVLERRRVHAGVRLIVIPGTQEIYRQ------- 338
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
A + IF +AG ++P+CG CLGG AR + V+TTNRNF GRMGH E
Sbjct: 339 -AMEEGLLAIFIQAGAAV-STPTCGPCLGGHMGVLAR---GERAVATTNRNFVGRMGHPE 393
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
++YL +P AAASA+ GR+A P E
Sbjct: 394 SEVYLTNPAVAAASAVLGRIAHPGE 418
[199][TOP]
>UniRef100_B0PCM1 Putative uncharacterized protein n=1 Tax=Anaerotruncus colihominis
DSM 17241 RepID=B0PCM1_9FIRM
Length = 396
Score = 97.1 bits (240), Expect = 1e-18
Identities = 59/145 (40%), Positives = 78/145 (53%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RE + VK+ +V +GSCT G+ D AK F V T +V A++ V ++ A
Sbjct: 261 REVEGVKVTQVVVGSCTNGRINDMEQVAKAFEGKHVHPDVNTLIVPASRDVLEEMEA--- 317
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
+ +I +AG T +P CG C G +E V VSTTNRNFPGRMG
Sbjct: 318 -----RGWCKIIRDAGA-TVLNPGCGPCFGAHEGL---TSERDVVVSTTNRNFPGRMGSM 368
Query: 264 EGQIYLASPYTAAASALTGRVADPR 190
+ IYLASP TAAA+AL GR+ P+
Sbjct: 369 KANIYLASPATAAATALAGRITVPK 393
[200][TOP]
>UniRef100_B5IER5 Homoaconitate hydratase family protein n=1 Tax=Aciduliprofundum
boonei T469 RepID=B5IER5_9EURY
Length = 418
Score = 97.1 bits (240), Expect = 1e-18
Identities = 55/147 (37%), Positives = 80/147 (54%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
+ + +++++V++G+CT G+ ED AA++ V + A+ VW +
Sbjct: 284 KAEGIEVNQVFLGTCTNGRVEDLEIAARILKGKKVNKNVRMLVFPASWDVWRE------- 336
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
A K + EAG +P CG CLG A A + + C+ST NRNF GRMG+
Sbjct: 337 -ADEKGILRTLAEAGA-VIMNPGCGPCLGAHAGVLA---DGEKCLSTANRNFKGRMGNPN 391
Query: 261 GQIYLASPYTAAASALTGRVADPREFL 181
+IYL SP TAAA+AL G +ADPRE L
Sbjct: 392 AEIYLGSPATAAATALKGYIADPREVL 418
[201][TOP]
>UniRef100_B5ICW8 Homoaconitate hydratase family protein n=1 Tax=Aciduliprofundum
boonei T469 RepID=B5ICW8_9EURY
Length = 419
Score = 97.1 bits (240), Expect = 1e-18
Identities = 55/144 (38%), Positives = 82/144 (56%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
+++ID+VYIG+CT G+ ED AAK+ K ++ A+++V++
Sbjct: 288 NIRIDQVYIGTCTNGRIEDLRVAAKILDGNKVNKKTRLIVIPASRRVYIQALK------- 340
Query: 432 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
+ + F EAG SP CG C+G A + + +ST NRNF GRMG+ +I
Sbjct: 341 -EGLLEKFVEAGAAIE-SPGCGPCVGIHKGVLA---DGERVLSTQNRNFKGRMGNPNAEI 395
Query: 252 YLASPYTAAASALTGRVADPREFL 181
YL SP TAAA+A+ G++ADPRE+L
Sbjct: 396 YLGSPATAAATAIEGKIADPREYL 419
[202][TOP]
>UniRef100_B5IBC4 Homoaconitate hydratase family protein n=1 Tax=Aciduliprofundum
boonei T469 RepID=B5IBC4_9EURY
Length = 419
Score = 97.1 bits (240), Expect = 1e-18
Identities = 55/144 (38%), Positives = 82/144 (56%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
+++ID+VYIG+CT G+ ED AAK+ K ++ A+++V++
Sbjct: 288 NIRIDQVYIGTCTNGRIEDLRVAAKILDGNKVNKKTRLIVIPASRRVYIQALK------- 340
Query: 432 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
+ + F EAG SP CG C+G A + + +ST NRNF GRMG+ +I
Sbjct: 341 -EGLLEKFVEAGAAIE-SPGCGPCVGIHKGVLA---DGERVLSTQNRNFKGRMGNPNAEI 395
Query: 252 YLASPYTAAASALTGRVADPREFL 181
YL SP TAAA+A+ G++ADPRE+L
Sbjct: 396 YLGSPATAAATAIEGKIADPREYL 419
[203][TOP]
>UniRef100_Q7M9Z9 3-isopropylmalate dehydratase large subunit n=1 Tax=Wolinella
succinogenes RepID=LEUC_WOLSU
Length = 422
Score = 97.1 bits (240), Expect = 1e-18
Identities = 55/142 (38%), Positives = 79/142 (55%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
D+KID+ +IGSCT G+ D AA++ V + TQ+++ D +
Sbjct: 292 DLKIDQAFIGSCTNGRLSDLRIAAQILKGKRVHPDVRLIITPGTQQIYKDAHQ------- 344
Query: 432 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
+ EAG ++P+CGACLGG L + + CVSTTNRNF GRMG + ++
Sbjct: 345 -EGLIDTLLEAGA-LISNPTCGACLGGYMGI---LGDNERCVSTTNRNFVGRMGARSSEV 399
Query: 252 YLASPYTAAASALTGRVADPRE 187
YLA+ AAASAL G++ DPR+
Sbjct: 400 YLANSAVAAASALKGKITDPRK 421
[204][TOP]
>UniRef100_B1L9K1 3-isopropylmalate dehydratase n=1 Tax=Thermotoga sp. RQ2
RepID=B1L9K1_THESQ
Length = 418
Score = 96.7 bits (239), Expect = 1e-18
Identities = 57/147 (38%), Positives = 81/147 (55%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + +KID+V+IG+CT G+ +D A K+ G+ V + A++KV+MD
Sbjct: 284 EKEKIKIDQVFIGTCTNGRLQDLEIALKILEKHGKHPDVRLIVGPASRKVYMDALE---- 339
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
K + F E G P CG C+G L + + +ST NRNF GRMG+
Sbjct: 340 ----KGIIKKFVELGAAV-IPPGCGPCVGIHMGV---LGDGERVLSTQNRNFKGRMGNPN 391
Query: 261 GQIYLASPYTAAASALTGRVADPREFL 181
+IYLASP TAAA+A+TG + DPR F+
Sbjct: 392 AEIYLASPATAAATAVTGYITDPRRFI 418
[205][TOP]
>UniRef100_C7IAQ1 3-isopropylmalate dehydratase n=1 Tax=Thermotoga naphthophila
RKU-10 RepID=C7IAQ1_9THEM
Length = 418
Score = 96.7 bits (239), Expect = 1e-18
Identities = 57/147 (38%), Positives = 81/147 (55%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + +KID+V+IG+CT G+ +D A K+ G+ V + A++KV+MD
Sbjct: 284 EKEKIKIDQVFIGTCTNGRLQDLEIALKILEKHGKHPDVRLIVGPASRKVYMDALE---- 339
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
K + F E G P CG C+G L + + +ST NRNF GRMG+
Sbjct: 340 ----KGIIKKFVELGAAV-IPPGCGPCVGIHMGV---LGDGERVLSTQNRNFKGRMGNPN 391
Query: 261 GQIYLASPYTAAASALTGRVADPREFL 181
+IYLASP TAAA+A+TG + DPR F+
Sbjct: 392 AEIYLASPATAAATAVTGYITDPRRFI 418
[206][TOP]
>UniRef100_C4FI11 3-isopropylmalate dehydratase, large subunit n=1
Tax=Sulfurihydrogenibium yellowstonense SS-5
RepID=C4FI11_9AQUI
Length = 431
Score = 96.7 bits (239), Expect = 1e-18
Identities = 57/145 (39%), Positives = 79/145 (54%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E ID+V+IGSCT G+ D AA + +V ++ A+ +++
Sbjct: 286 EVAGTHIDQVFIGSCTNGRLSDLRIAAAILKGKKVHPEVRCIVIPASDQIYKQ------- 338
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
A + +I EAGC S +CG CLGG A E +VC+ST+NRNF GRMGH +
Sbjct: 339 -ALHEGIIEILAEAGCLISTS-TCGPCLGGHMGILA---EGEVCLSTSNRNFVGRMGHPK 393
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
Q+YL+SP AAASA+ GR+ P E
Sbjct: 394 SQVYLSSPAVAAASAVLGRIVHPDE 418
[207][TOP]
>UniRef100_A5IKB8 3-isopropylmalate dehydratase, large subunit n=2 Tax=Thermotogaceae
RepID=A5IKB8_THEP1
Length = 418
Score = 96.7 bits (239), Expect = 1e-18
Identities = 57/147 (38%), Positives = 81/147 (55%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + +KID+V+IG+CT G+ +D A K+ G+ V + A++KV+MD
Sbjct: 284 EKEKIKIDQVFIGTCTNGRLQDLEIALKILEKHGKHPDVRLIVGPASRKVYMDALE---- 339
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
K + F E G P CG C+G L + + +ST NRNF GRMG+
Sbjct: 340 ----KGIIKKFVELGAAV-IPPGCGPCVGIHMGV---LGDGERVLSTQNRNFKGRMGNPN 391
Query: 261 GQIYLASPYTAAASALTGRVADPREFL 181
+IYLASP TAAA+A+TG + DPR F+
Sbjct: 392 AEIYLASPATAAATAVTGYITDPRRFI 418
[208][TOP]
>UniRef100_B9L6Y8 3-isopropylmalate dehydratase large subunit n=1 Tax=Nautilia
profundicola AmH RepID=LEUC_NAUPA
Length = 425
Score = 96.7 bits (239), Expect = 1e-18
Identities = 55/142 (38%), Positives = 81/142 (57%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
D++ID+VYIGSCT G D AA++ +V + ATQ+++ A
Sbjct: 295 DIEIDQVYIGSCTNGTLSDLRIAAEILKGKRVHRRVRLIVTPATQRIYKQ--------AE 346
Query: 432 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
+ I +AG A+P+CGACLGG L + + V+TTNRNF GRMG + ++
Sbjct: 347 HEGILDILIDAGA-VVANPTCGACLGGYMGI---LGDGERAVATTNRNFRGRMGSRSSEV 402
Query: 252 YLASPYTAAASALTGRVADPRE 187
YL++ AAASA+ G++ADPR+
Sbjct: 403 YLSNSAVAAASAIAGKIADPRD 424
[209][TOP]
>UniRef100_Q9WYC7 3-isopropylmalate dehydratase large subunit 1 n=1 Tax=Thermotoga
maritima RepID=LEUC1_THEMA
Length = 418
Score = 96.7 bits (239), Expect = 1e-18
Identities = 57/147 (38%), Positives = 81/147 (55%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + +KID+V+IG+CT G+ +D A K+ G+ V + A++KV+MD
Sbjct: 284 EKEKIKIDQVFIGTCTNGRLQDLEIALKILEKHGKHPDVRLIVGPASRKVYMDALE---- 339
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
K + F E G P CG C+G L + + +ST NRNF GRMG+
Sbjct: 340 ----KGIIKKFVELGAAV-IPPGCGPCVGIHMGV---LGDGERVLSTQNRNFKGRMGNPN 391
Query: 261 GQIYLASPYTAAASALTGRVADPREFL 181
+IYLASP TAAA+A+TG + DPR F+
Sbjct: 392 AEIYLASPATAAATAVTGYITDPRRFI 418
[210][TOP]
>UniRef100_B0TCR2 3-isopropylmalate dehydratase large subunit n=1 Tax=Heliobacterium
modesticaldum Ice1 RepID=LEUC_HELMI
Length = 420
Score = 96.3 bits (238), Expect = 2e-18
Identities = 56/145 (38%), Positives = 76/145 (52%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E V+ID+V IGSCT G+ ED AAK+ V + TQ ++
Sbjct: 286 EAGHVEIDQVVIGSCTNGRIEDLRMAAKILQGKKVHKNVRCIIFPGTQAIYKQAIK---- 341
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
+ IF +AG ++P+CG CLGG A+ + ++TTNRNF GRMGH E
Sbjct: 342 ----EGLIDIFIDAGAAV-STPTCGPCLGGHMGILAK---GERALATTNRNFVGRMGHPE 393
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
++YL P AAASA+ GR+ PRE
Sbjct: 394 SEVYLCGPNVAAASAIAGRIVHPRE 418
[211][TOP]
>UniRef100_B9MLV4 3-isopropylmalate dehydratase large subunit n=1 Tax=Anaerocellum
thermophilum DSM 6725 RepID=LEUC_ANATD
Length = 429
Score = 96.3 bits (238), Expect = 2e-18
Identities = 58/143 (40%), Positives = 81/143 (56%), Gaps = 2/143 (1%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVPGA 436
+ ID+V IGSCT G+ ED AAK+ GRKVK + + ATQ ++
Sbjct: 293 IYIDQVVIGSCTNGRIEDLRIAAKILK--GRKVKKGLRCIIFPATQNIYKQALK------ 344
Query: 435 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 256
+ +IF +AGC ++P+CG CLGG A + + ++TTNRNF GRMGH +
Sbjct: 345 --EGFIEIFIDAGC-VVSTPTCGPCLGGHMGILA---DGEKALATTNRNFVGRMGHPNSE 398
Query: 255 IYLASPYTAAASALTGRVADPRE 187
+YL+SP AAASA+ G + P E
Sbjct: 399 VYLSSPAIAAASAVLGYIGSPEE 421
[212][TOP]
>UniRef100_B1L5I9 3-isopropylmalate dehydratase n=1 Tax=Candidatus Korarchaeum
cryptofilum OPF8 RepID=B1L5I9_KORCO
Length = 413
Score = 95.9 bits (237), Expect = 2e-18
Identities = 58/153 (37%), Positives = 83/153 (54%), Gaps = 6/153 (3%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + ++D V+IGSC+GG+ EDF+ A+++ K V V A+++V M +
Sbjct: 278 EVEGEEVDLVFIGSCSGGRFEDFLLASRIMRGRKLKEGVRCITVPASKEVQMKLI----- 332
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLG------GPADTYARLNEPQVCVSTTNRNFPG 280
+ E GC T P+CG C+G GP +T VST+ RNFPG
Sbjct: 333 ---DSGLMRSLLEFGC-TVGPPTCGPCIGAHMGLAGPGETV---------VSTSTRNFPG 379
Query: 279 RMGHKEGQIYLASPYTAAASALTGRVADPREFL 181
RMG + ++YLASP TAAASA+ G++ DP FL
Sbjct: 380 RMGSPDSRVYLASPLTAAASAVEGKLTDPGRFL 412
[213][TOP]
>UniRef100_C8SB74 Homoaconitate hydratase family protein n=1 Tax=Ferroglobus placidus
DSM 10642 RepID=C8SB74_FERPL
Length = 419
Score = 95.9 bits (237), Expect = 2e-18
Identities = 57/145 (39%), Positives = 80/145 (55%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + VKID+V+IGSCT G+ ED AA++ V ++ A++ +
Sbjct: 286 EVEGVKIDQVFIGSCTNGRYEDLKVAAEILKGEKVAKGVRLIVIPASRSHYKRALK---- 341
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
+ IF EAG PSCG C+GG ++ + +V +ST+NRNF GR G E
Sbjct: 342 ----EGLIDIFVEAGAIVEF-PSCGPCMGG---SFGLIASKEVSLSTSNRNFIGRQGSPE 393
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
G+IYL SP TAAASA+ G + DPR+
Sbjct: 394 GEIYLCSPATAAASAIYGEITDPRK 418
[214][TOP]
>UniRef100_Q1Q122 Similar to 3-isopropylmalate dehydratase, large subunit n=1
Tax=Candidatus Kuenenia stuttgartiensis
RepID=Q1Q122_9BACT
Length = 437
Score = 95.5 bits (236), Expect = 3e-18
Identities = 54/141 (38%), Positives = 78/141 (55%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGG 430
+KID+V IGSCT G+ D AAK+ + ++ ATQ+++
Sbjct: 297 IKIDQVVIGSCTNGRISDLRIAAKILKGKKAHPSLRLIIIPATQEIYKQALK-------- 348
Query: 429 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 250
+ +IF +A ++P+CG CLGG A E + ++TTNRNF GRMGH + +IY
Sbjct: 349 EGLIEIFIDAEA-VVSTPTCGPCLGGHMGILA---EGERALTTTNRNFVGRMGHPKSEIY 404
Query: 249 LASPYTAAASALTGRVADPRE 187
L SP AAASA+TG++ P E
Sbjct: 405 LCSPAVAAASAITGKITPPSE 425
[215][TOP]
>UniRef100_Q1NU24 Cis-homoaconitase:3-isopropylmalate dehydratase, prokaryotic n=1
Tax=delta proteobacterium MLMS-1 RepID=Q1NU24_9DELT
Length = 428
Score = 95.5 bits (236), Expect = 3e-18
Identities = 64/144 (44%), Positives = 84/144 (58%), Gaps = 3/144 (2%)
Frame = -3
Query: 603 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKV--KVPTFLVTATQKVWMDVYALPVPGAGG 430
+D++YIGSCT G+ ED AA++ GRK+ +V L AT KV A
Sbjct: 300 VDQIYIGSCTNGRIEDLREAARIL--KGRKISEQVRGILAPATPKV--------AAQALE 349
Query: 429 KTCAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
+ +IF EAG C T +P+CGACLG A E ++C STTNRNF GRMG K G +
Sbjct: 350 EGILKIFMEAGFCVT--NPTCGACLGMSNGVLA---EGEICASTTNRNFNGRMG-KGGIV 403
Query: 252 YLASPYTAAASALTGRVADPREFL 181
+L SP +AAA+A+ G + DPR L
Sbjct: 404 HLMSPLSAAAAAVAGHITDPRPLL 427
[216][TOP]
>UniRef100_Q1NII2 Cis-homoaconitase:3-isopropylmalate dehydratase, prokaryotic n=1
Tax=delta proteobacterium MLMS-1 RepID=Q1NII2_9DELT
Length = 428
Score = 95.5 bits (236), Expect = 3e-18
Identities = 64/144 (44%), Positives = 84/144 (58%), Gaps = 3/144 (2%)
Frame = -3
Query: 603 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKV--KVPTFLVTATQKVWMDVYALPVPGAGG 430
+D++YIGSCT G+ ED AA++ GRK+ +V L AT KV A
Sbjct: 300 VDQIYIGSCTNGRIEDLREAARIL--KGRKISEQVRGILAPATPKV--------AAQALE 349
Query: 429 KTCAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
+ +IF EAG C T +P+CGACLG A E ++C STTNRNF GRMG K G +
Sbjct: 350 EGILKIFMEAGFCVT--NPTCGACLGMSNGVLA---EGEICASTTNRNFNGRMG-KGGIV 403
Query: 252 YLASPYTAAASALTGRVADPREFL 181
+L SP +AAA+A+ G + DPR L
Sbjct: 404 HLMSPLSAAAAAVAGHITDPRPLL 427
[217][TOP]
>UniRef100_C1I927 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium sp.
7_2_43FAA RepID=C1I927_9CLOT
Length = 424
Score = 95.5 bits (236), Expect = 3e-18
Identities = 56/145 (38%), Positives = 78/145 (53%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E +V +D+V IGSCT G+ D A + K V + TQK+++ +
Sbjct: 286 EVGEVAVDQVVIGSCTNGRISDLRVARDILKNKKVKKGVRCIVFPGTQKIYLQALEEGI- 344
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
+ EAG ++P+CG CLGG A+ + +STTNRNF GRMGH E
Sbjct: 345 -------IKDLVEAGA-VVSTPTCGPCLGGHMGILAK---GERAISTTNRNFVGRMGHVE 393
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
++YLASP AAASALTG++ +P E
Sbjct: 394 SEVYLASPAVAAASALTGKITNPEE 418
[218][TOP]
>UniRef100_Q703X6 3-isopropylmalate dehydratase large subunit n=1 Tax=Thermoproteus
tenax RepID=Q703X6_THETE
Length = 415
Score = 95.5 bits (236), Expect = 3e-18
Identities = 56/148 (37%), Positives = 83/148 (56%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RE + V++D+V+IGSCT G+ D AAA++ + K + A+ V+
Sbjct: 282 REVEGVEVDQVFIGSCTNGRLSDIEAAARILKRG--RAKARCIAIPASYSVFRQALE--- 336
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
AG + +AGC +CG C+GG + L + VST+NRNF GRMG
Sbjct: 337 --AG---YIDVLTKAGCVVTYG-TCGPCIGGH---FGVLGPGETAVSTSNRNFVGRMGAN 387
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
+ ++YLA+ YTAAA+AL GR+ DPR++L
Sbjct: 388 DSKVYLANAYTAAAAALEGRIVDPRKYL 415
[219][TOP]
>UniRef100_A3MWJ4 3-isopropylmalate dehydratase large subunit n=1 Tax=Pyrobaculum
calidifontis JCM 11548 RepID=LEUC_PYRCJ
Length = 413
Score = 95.5 bits (236), Expect = 3e-18
Identities = 53/147 (36%), Positives = 82/147 (55%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + +++D+V+IGSCT G+ D AAK+ +VK + A+ V+ L
Sbjct: 281 EVEGIEVDQVFIGSCTNGRLSDIEVAAKILRHG--RVKARCIAIPASYDVFRRAMELGY- 337
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
+ +AGC +CG CLGG + +V ++T+NRNF GR+GH +
Sbjct: 338 -------VDVLTKAGCVVTYG-TCGPCLGGH---FGVAGPGEVVLTTSNRNFKGRVGHPD 386
Query: 261 GQIYLASPYTAAASALTGRVADPREFL 181
++YLA+P AAA+ALTGR+ DPR++L
Sbjct: 387 SKVYLANPAVAAATALTGRITDPRQYL 413
[220][TOP]
>UniRef100_Q3AEQ4 3-isopropylmalate dehydratase, large subunit n=1
Tax=Carboxydothermus hydrogenoformans Z-2901
RepID=Q3AEQ4_CARHZ
Length = 421
Score = 95.1 bits (235), Expect = 4e-18
Identities = 59/148 (39%), Positives = 80/148 (54%), Gaps = 2/148 (1%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYAL 451
+E ID+V IGSCT G+ ED AA + G+KVK V ++ +Q V+
Sbjct: 286 KEVSGKDIDQVVIGSCTNGRIEDLRVAAAILK--GKKVKDYVRCIIIPGSQSVYRQALK- 342
Query: 450 PVPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMG 271
+ IF EAG ++P+CG CLGG A+ + V+TTNRNF GRMG
Sbjct: 343 -------EGLIDIFLEAGAAV-STPTCGPCLGGHMGILAK---GERAVATTNRNFVGRMG 391
Query: 270 HKEGQIYLASPYTAAASALTGRVADPRE 187
H E ++YLA P AAASA+ G++ P E
Sbjct: 392 HVESEVYLAGPAVAAASAIAGKIVHPEE 419
[221][TOP]
>UniRef100_C0QS35 3-isopropylmalate dehydratase, large subunit n=1 Tax=Persephonella
marina EX-H1 RepID=C0QS35_PERMH
Length = 428
Score = 95.1 bits (235), Expect = 4e-18
Identities = 59/141 (41%), Positives = 80/141 (56%), Gaps = 2/141 (1%)
Frame = -3
Query: 603 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVTATQKVWMDVYALPVPGAGG 430
I++V+IGSCT G+ D AA + GRKV V ++ A+ +++ A
Sbjct: 292 INQVFIGSCTNGRMSDLRIAAHILK--GRKVHPDVRCIVIPASDRIYKQ--------ALH 341
Query: 429 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 250
+ +I +AGC S +CG CLGG A E +VCVST+NRNF GRMGH ++Y
Sbjct: 342 EGILEILADAGCLISTS-TCGPCLGGHMGILA---EGEVCVSTSNRNFTGRMGHPNSEVY 397
Query: 249 LASPYTAAASALTGRVADPRE 187
LA P AAASA+ GR+A P E
Sbjct: 398 LAGPAVAAASAVLGRIAHPDE 418
[222][TOP]
>UniRef100_Q1K341 Homoaconitate hydratase family protein n=1 Tax=Desulfuromonas
acetoxidans DSM 684 RepID=Q1K341_DESAC
Length = 427
Score = 95.1 bits (235), Expect = 4e-18
Identities = 60/145 (41%), Positives = 81/145 (55%), Gaps = 1/145 (0%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E +D++YIG+CT G+ ED AA + V + AT K++ D A
Sbjct: 294 EMAGAPVDQIYIGTCTNGRIEDLREAAAILKGRRIADTVRGIVSPATPKIFRDALA---- 349
Query: 441 GAGGKTCAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
+ QIF +AG C T +P+CGACLG A E +VC ST+NRNF GRMG K
Sbjct: 350 ----EGIIQIFMDAGFCVT--NPTCGACLGMSNGVLA---EGEVCASTSNRNFNGRMG-K 399
Query: 264 EGQIYLASPYTAAASALTGRVADPR 190
G ++L SP TAAA+A+TG++ D R
Sbjct: 400 GGMVHLMSPATAAATAITGKITDAR 424
[223][TOP]
>UniRef100_C9KJM7 3-isopropylmalate dehydratase, large subunit n=2 Tax=Mitsuokella
multacida DSM 20544 RepID=C9KJM7_9FIRM
Length = 420
Score = 95.1 bits (235), Expect = 4e-18
Identities = 54/141 (38%), Positives = 77/141 (54%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGG 430
++ID+V IGSCT G+ ED AA + +V ++ + ++ +
Sbjct: 290 IEIDQVIIGSCTNGRLEDMEIAASILKGHKVADRVRCIVIPGSPAIYKESMK-------- 341
Query: 429 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 250
+ F +AGC ++P+CG CLGG A + CVSTTNRNF GRMGH + ++Y
Sbjct: 342 RGYIDTFIDAGCAV-STPTCGPCLGGYMGIMAA---GERCVSTTNRNFRGRMGHVDSEVY 397
Query: 249 LASPYTAAASALTGRVADPRE 187
LA P AAASA+ GR+A P E
Sbjct: 398 LAGPQVAAASAILGRIATPEE 418
[224][TOP]
>UniRef100_B1YD98 3-isopropylmalate dehydratase large subunit n=1 Tax=Thermoproteus
neutrophilus V24Sta RepID=LEUC_THENV
Length = 415
Score = 95.1 bits (235), Expect = 4e-18
Identities = 54/148 (36%), Positives = 82/148 (55%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
RE + V++D+V+IGSCT G+ DF AA++ + K + A+ V+ L
Sbjct: 280 REVEGVEVDQVFIGSCTNGRLSDFEVAARVLKRG--RAKARCIAIPASYAVFRRAMELGY 337
Query: 444 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 265
+ +AGC +CG CLGG + +V V+T+NRNF GR+GH
Sbjct: 338 --------IDVLTKAGCVVTYG-TCGPCLGGH---FGVAGPGEVVVTTSNRNFKGRVGHP 385
Query: 264 EGQIYLASPYTAAASALTGRVADPREFL 181
+ ++YLA+P TAAA+AL G++ DPR +L
Sbjct: 386 DSKVYLANPATAAAAALEGKIVDPRPYL 413
[225][TOP]
>UniRef100_B8J825 3-isopropylmalate dehydratase large subunit n=1
Tax=Anaeromyxobacter dehalogenans 2CP-1 RepID=LEUC_ANAD2
Length = 480
Score = 95.1 bits (235), Expect = 4e-18
Identities = 61/143 (42%), Positives = 79/143 (55%)
Frame = -3
Query: 606 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGGK 427
K+D V+IGSCT G+ ED AA++ GRKV+ T +V + +V D A +
Sbjct: 351 KVDVVFIGSCTNGRIEDMREAARVLK--GRKVRTRTLVVPGSHRVKKDAEAEGID----- 403
Query: 426 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 247
+I EAG + P C C+ D L Q CVST+NRNF GR G G+ L
Sbjct: 404 ---RIVREAGAEW-REPGCSMCIAMNGDN---LQAGQYCVSTSNRNFEGRQG-PGGRTLL 455
Query: 246 ASPYTAAASALTGRVADPREFLQ 178
ASP TAAA+A+TG VADPR L+
Sbjct: 456 ASPLTAAAAAVTGAVADPRRVLE 478
[226][TOP]
>UniRef100_B9KC23 3-isopropylmalate dehydratase large subunit 1 n=1 Tax=Thermotoga
neapolitana DSM 4359 RepID=B9KC23_THENN
Length = 420
Score = 94.7 bits (234), Expect = 5e-18
Identities = 56/147 (38%), Positives = 81/147 (55%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + +KID+V+IG+CT G+ +D A ++ G+ V + A++KV+MD
Sbjct: 286 EKEKIKIDQVFIGTCTNGRLQDLEIALRILEKHGKHPDVRLIVGPASRKVYMDALE---- 341
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
K + F E G P CG C+G L + + +ST NRNF GRMG+
Sbjct: 342 ----KGIIKRFVELGAAI-IPPGCGPCVGIHMGV---LGDGERVLSTQNRNFKGRMGNPN 393
Query: 261 GQIYLASPYTAAASALTGRVADPREFL 181
+IYLASP TAAA+A+ G +ADPR F+
Sbjct: 394 AEIYLASPATAAATAVAGYIADPRRFI 420
[227][TOP]
>UniRef100_C9RD99 3-isopropylmalate dehydratase n=1 Tax=Ammonifex degensii KC4
RepID=C9RD99_9THEO
Length = 418
Score = 94.7 bits (234), Expect = 5e-18
Identities = 59/145 (40%), Positives = 83/145 (57%), Gaps = 2/145 (1%)
Frame = -3
Query: 606 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKV--KVPTFLVTATQKVWMDVYALPVPGAG 433
KID+ +IG+CT G+ ED AA++ AGRK+ +V + A++KV++ A
Sbjct: 288 KIDQAFIGTCTNGRLEDLRVAARIL--AGRKIHPRVRLVVAPASRKVYLQ--------AM 337
Query: 432 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
+ EAG +P CG C+G A + +V VST NRNF GRMG+ + +I
Sbjct: 338 REGILATLVEAGAAV-VTPGCGPCVGTHNGVPA---DGEVVVSTANRNFKGRMGNAKAEI 393
Query: 252 YLASPYTAAASALTGRVADPREFLQ 178
YLASP T AASA+ G + DPR FL+
Sbjct: 394 YLASPATVAASAIAGEITDPRLFLK 418
[228][TOP]
>UniRef100_C8SBC1 Homoaconitate hydratase family protein n=1 Tax=Ferroglobus placidus
DSM 10642 RepID=C8SBC1_FERPL
Length = 427
Score = 94.7 bits (234), Expect = 5e-18
Identities = 57/149 (38%), Positives = 85/149 (57%), Gaps = 2/149 (1%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVT--ATQKVWMDVYALP 448
E + VK+D+V++G+CT G+ D A++ GRKV L+ A+++V+M
Sbjct: 293 EVEGVKVDQVFVGTCTNGRLSDLEVVARILK--GRKVHKDVRLLVGPASREVYMKALERG 350
Query: 447 VPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGH 268
+I + G P P CG C+G A + +VC+ST NRNF GRMG+
Sbjct: 351 Y-------IQEIIKAGGVILP--PGCGPCVGIHLGILA---DGEVCLSTQNRNFKGRMGN 398
Query: 267 KEGQIYLASPYTAAASALTGRVADPREFL 181
+IYL+SP TAAASA+ G++ADPR++L
Sbjct: 399 PNAEIYLSSPATAAASAIEGKIADPRKYL 427
[229][TOP]
>UniRef100_UPI0001A42D5E isopropylmalate isomerase large subunit n=1 Tax=Pectobacterium
carotovorum subsp. carotovorum WPP14 RepID=UPI0001A42D5E
Length = 466
Score = 94.4 bits (233), Expect = 7e-18
Identities = 67/149 (44%), Positives = 84/149 (56%), Gaps = 7/149 (4%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
DVKID+V+IGSCT + ED AAA++ A GRKV V A+ VPG+G
Sbjct: 336 DVKIDKVFIGSCTNSRIEDLRAAAEI--AKGRKVAA-------------GVQAIVVPGSG 380
Query: 432 G-KTCAQ------IFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRM 274
KT A+ +F EAG + P C CL D RLN + C ST+NRNF GR
Sbjct: 381 PVKTMAELEGLDKVFIEAGFEW-RLPGCSMCLAMNND---RLNPGERCASTSNRNFEGRQ 436
Query: 273 GHKEGQIYLASPYTAAASALTGRVADPRE 187
G + G+ +L SP AAA+A+TGR AD RE
Sbjct: 437 G-RAGRTHLVSPAMAAAAAVTGRFADVRE 464
[230][TOP]
>UniRef100_UPI0001A42783 isopropylmalate isomerase large subunit n=1 Tax=Pectobacterium
carotovorum subsp. brasiliensis PBR1692
RepID=UPI0001A42783
Length = 466
Score = 94.4 bits (233), Expect = 7e-18
Identities = 67/149 (44%), Positives = 84/149 (56%), Gaps = 7/149 (4%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
DVKID+V+IGSCT + ED AAA++ A GRKV V A+ VPG+G
Sbjct: 336 DVKIDKVFIGSCTNSRIEDLRAAAEI--AKGRKVAA-------------GVQAIVVPGSG 380
Query: 432 G-KTCAQ------IFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRM 274
KT A+ +F EAG + P C CL D RLN + C ST+NRNF GR
Sbjct: 381 PVKTMAELEGLDKVFIEAGFEW-RLPGCSMCLAMNND---RLNPGERCASTSNRNFEGRQ 436
Query: 273 GHKEGQIYLASPYTAAASALTGRVADPRE 187
G + G+ +L SP AAA+A+TGR AD RE
Sbjct: 437 G-RAGRTHLVSPAMAAAAAVTGRFADVRE 464
[231][TOP]
>UniRef100_C6NDA0 3-isopropylmalate dehydratase, large subunit n=1 Tax=Pectobacterium
wasabiae WPP163 RepID=C6NDA0_9ENTR
Length = 466
Score = 94.4 bits (233), Expect = 7e-18
Identities = 67/149 (44%), Positives = 84/149 (56%), Gaps = 7/149 (4%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
DVKID+V+IGSCT + ED AAA++ A GRKV V A+ VPG+G
Sbjct: 336 DVKIDKVFIGSCTNSRIEDLRAAAEI--AKGRKVAA-------------GVQAIVVPGSG 380
Query: 432 G-KTCAQ------IFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRM 274
KT A+ +F EAG + P C CL D RLN + C ST+NRNF GR
Sbjct: 381 PVKTMAELEGLDKVFIEAGFEW-RLPGCSMCLAMNND---RLNPGERCASTSNRNFEGRQ 436
Query: 273 GHKEGQIYLASPYTAAASALTGRVADPRE 187
G + G+ +L SP AAA+A+TGR AD RE
Sbjct: 437 G-RAGRTHLVSPAMAAAAAVTGRFADVRE 464
[232][TOP]
>UniRef100_C4V4K3 3-isopropylmalate dehydratase n=1 Tax=Selenomonas flueggei ATCC
43531 RepID=C4V4K3_9FIRM
Length = 420
Score = 94.4 bits (233), Expect = 7e-18
Identities = 56/141 (39%), Positives = 77/141 (54%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGG 430
+ ID+V IGSCT G+ ED AA + +V ++ + V+ +
Sbjct: 290 IAIDQVVIGSCTNGRLEDMEIAASILKGHKVHERVRCIVIPGSPYVYEESMK-------- 341
Query: 429 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 250
+ IF EAG ++P+CG CLGG A + CVSTTNRNF GRMGH + ++Y
Sbjct: 342 RGYLAIFMEAGAAI-STPTCGPCLGGYMGILAA---GERCVSTTNRNFRGRMGHVDSEVY 397
Query: 249 LASPYTAAASALTGRVADPRE 187
LA P+ AAASA+ GR+A P E
Sbjct: 398 LAGPHVAAASAILGRIAAPEE 418
[233][TOP]
>UniRef100_B6BGP4 3-isopropylmalate dehydratase large subunit n=1
Tax=Campylobacterales bacterium GD 1 RepID=B6BGP4_9PROT
Length = 419
Score = 94.4 bits (233), Expect = 7e-18
Identities = 55/140 (39%), Positives = 76/140 (54%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGG 430
+KID+ +IGSCT G+ D AA++ V + TQK+ + Y L
Sbjct: 292 IKIDQAFIGSCTNGRLGDLKTAAEILDGKKVHEDVRLIVTPGTQKILKEAYRLGY----- 346
Query: 429 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 250
I +AG ++P+CGACLGG L + +V VSTTNRNF GRMG + ++Y
Sbjct: 347 ---MDIIIDAG-GVVSNPTCGACLGGYMGI---LGDNEVAVSTTNRNFVGRMGSRSSKVY 399
Query: 249 LASPYTAAASALTGRVADPR 190
LA+ AA SA+TG + DPR
Sbjct: 400 LANSAVAAISAITGYITDPR 419
[234][TOP]
>UniRef100_A1HUD1 Homoaconitate hydratase family protein n=1 Tax=Thermosinus
carboxydivorans Nor1 RepID=A1HUD1_9FIRM
Length = 419
Score = 94.4 bits (233), Expect = 7e-18
Identities = 60/147 (40%), Positives = 84/147 (57%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + I + Y+GSCT G+ D + AAK+ GRKV L+ + +Y V
Sbjct: 285 EAEGEVIHQAYLGSCTNGRYPDLVEAAKILK--GRKVHPDVRLLVSPAS--RSIYHRAVR 340
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
+ +I +AG A PSCGACLG + AR + +S+TNRNF GRMGHKE
Sbjct: 341 ----EGIIEILSDAGAMILA-PSCGACLGLHSGILAR---GERAISSTNRNFVGRMGHKE 392
Query: 261 GQIYLASPYTAAASALTGRVADPREFL 181
+I+LASP + AA+A+ G++ DPR+FL
Sbjct: 393 AEIFLASPASVAAAAIEGKITDPRKFL 419
[235][TOP]
>UniRef100_B5IBY4 Homoaconitate hydratase family protein n=1 Tax=Aciduliprofundum
boonei T469 RepID=B5IBY4_9EURY
Length = 409
Score = 94.4 bits (233), Expect = 7e-18
Identities = 57/144 (39%), Positives = 84/144 (58%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + ++ID +IGSCT G+ ED +AAAK+ G+K+KVP + T+++W+ +
Sbjct: 282 EYEGMEIDGAFIGSCTNGRYEDLVAAAKIL--KGKKLKVPLTITPTTREIWLRLMK---- 335
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
+ +IF EAG +P CG C A+ L +V +STTNRN+PG+ G
Sbjct: 336 ----EGIWEIFAEAGA-VLTNPGCGGC----AEGMPGLIGDEVYLSTTNRNYPGKQG--P 384
Query: 261 GQIYLASPYTAAASALTGRVADPR 190
G++YL SP AAASA+ G+V PR
Sbjct: 385 GKLYLVSPVIAAASAVEGKVTVPR 408
[236][TOP]
>UniRef100_B5I9M1 Homoaconitate hydratase family protein n=1 Tax=Aciduliprofundum
boonei T469 RepID=B5I9M1_9EURY
Length = 409
Score = 94.4 bits (233), Expect = 7e-18
Identities = 57/144 (39%), Positives = 84/144 (58%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E + ++ID +IGSCT G+ ED +AAAK+ G+K+KVP + T+++W+ +
Sbjct: 282 EYEGMEIDGAFIGSCTNGRYEDLVAAAKIL--KGKKLKVPLTITPTTREIWLRLMK---- 335
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
+ +IF EAG +P CG C A+ L +V +STTNRN+PG+ G
Sbjct: 336 ----EGIWEIFAEAGA-VLTNPGCGGC----AEGMPGLIGDEVYLSTTNRNYPGKQG--P 384
Query: 261 GQIYLASPYTAAASALTGRVADPR 190
G++YL SP AAASA+ G+V PR
Sbjct: 385 GKLYLVSPVIAAASAVEGKVTVPR 408
[237][TOP]
>UniRef100_C6DEW0 3-isopropylmalate dehydratase large subunit n=1 Tax=Pectobacterium
carotovorum subsp. carotovorum PC1 RepID=LEUC_PECCP
Length = 466
Score = 94.4 bits (233), Expect = 7e-18
Identities = 67/149 (44%), Positives = 84/149 (56%), Gaps = 7/149 (4%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
DVKID+V+IGSCT + ED AAA++ A GRKV V A+ VPG+G
Sbjct: 336 DVKIDKVFIGSCTNSRIEDLRAAAEI--AKGRKVAA-------------GVQAIVVPGSG 380
Query: 432 G-KTCAQ------IFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRM 274
KT A+ +F EAG + P C CL D RLN + C ST+NRNF GR
Sbjct: 381 PVKTMAELEGLDKVFIEAGFEW-RLPGCSMCLAMNND---RLNPGERCASTSNRNFEGRQ 436
Query: 273 GHKEGQIYLASPYTAAASALTGRVADPRE 187
G + G+ +L SP AAA+A+TGR AD RE
Sbjct: 437 G-RAGRTHLVSPAMAAAAAVTGRFADVRE 464
[238][TOP]
>UniRef100_Q6D0G6 3-isopropylmalate dehydratase large subunit n=1 Tax=Pectobacterium
atrosepticum RepID=LEUC_ERWCT
Length = 466
Score = 94.4 bits (233), Expect = 7e-18
Identities = 67/149 (44%), Positives = 84/149 (56%), Gaps = 7/149 (4%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
DVKID+V+IGSCT + ED AAA++ A GRKV V A+ VPG+G
Sbjct: 336 DVKIDKVFIGSCTNSRIEDLRAAAEI--AKGRKVAA-------------GVQAIVVPGSG 380
Query: 432 G-KTCAQ------IFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRM 274
KT A+ +F EAG + P C CL D RLN + C ST+NRNF GR
Sbjct: 381 PVKTMAELEGLDKVFIEAGFEW-RLPGCSMCLAMNND---RLNPGERCASTSNRNFEGRQ 436
Query: 273 GHKEGQIYLASPYTAAASALTGRVADPRE 187
G + G+ +L SP AAA+A+TGR AD RE
Sbjct: 437 G-RAGRTHLVSPAMAAAAAVTGRFADVRE 464
[239][TOP]
>UniRef100_B4UAN0 3-isopropylmalate dehydratase large subunit n=1
Tax=Anaeromyxobacter sp. K RepID=LEUC_ANASK
Length = 480
Score = 94.4 bits (233), Expect = 7e-18
Identities = 60/143 (41%), Positives = 79/143 (55%)
Frame = -3
Query: 606 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGGK 427
K+D V+IGSCT G+ ED AA++ GRKV+ T +V + +V D A +
Sbjct: 351 KVDVVFIGSCTNGRIEDMREAARVLK--GRKVRTRTLVVPGSHRVKKDAEAEGID----- 403
Query: 426 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 247
+I EAG + P C C+ D + Q CVST+NRNF GR G G+ L
Sbjct: 404 ---RIVREAGAEW-REPGCSMCIAMNGDN---IQAGQYCVSTSNRNFEGRQG-PGGRTLL 455
Query: 246 ASPYTAAASALTGRVADPREFLQ 178
ASP TAAA+A+TG VADPR L+
Sbjct: 456 ASPLTAAAAAVTGAVADPRRVLE 478
[240][TOP]
>UniRef100_Q0AV21 3-isopropylmalate dehydratase, large subunit n=1 Tax=Syntrophomonas
wolfei subsp. wolfei str. Goettingen RepID=Q0AV21_SYNWW
Length = 419
Score = 94.0 bits (232), Expect = 9e-18
Identities = 54/145 (37%), Positives = 78/145 (53%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E V +D+V IGSCT G+ ED A L ++ + T++++++
Sbjct: 286 EATHVSLDQVVIGSCTNGRIEDMEITASLLKGQKVHPEIRVIIFPGTREIYLEALR---- 341
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
+ + F EAG ++P+CG CLGG AR + ++TTNRNF GRMGH E
Sbjct: 342 ----RGYIETFIEAGA-VVSTPTCGPCLGGHMGILAR---GEKALATTNRNFVGRMGHPE 393
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
++YLASP AAASA+ GR+ P E
Sbjct: 394 SEVYLASPAVAAASAVKGRITAPWE 418
[241][TOP]
>UniRef100_C3XG48 3-isopropylmalate dehydratase large subunit n=1 Tax=Helicobacter
bilis ATCC 43879 RepID=C3XG48_9HELI
Length = 420
Score = 94.0 bits (232), Expect = 9e-18
Identities = 54/144 (37%), Positives = 80/144 (55%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
++KID+V IGSCT G+ D AA + ++ ATQ ++++
Sbjct: 289 EIKIDQVVIGSCTNGRLSDMEVAANILKDKTIAKNTRCIIIPATQNIYLECI-------- 340
Query: 432 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
+ + F +AG ++P+CG CLGG A NE CVSTTNRNF GRMGH ++
Sbjct: 341 NRGYLETFIKAGA-VVSTPTCGPCLGGHMGILAA-NEK--CVSTTNRNFVGRMGHTTSEV 396
Query: 252 YLASPYTAAASALTGRVADPREFL 181
YL+SP AAASA+ G ++ P++ +
Sbjct: 397 YLSSPEVAAASAVRGILSSPQDII 420
[242][TOP]
>UniRef100_C0CU43 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
DSM 15981 RepID=C0CU43_9CLOT
Length = 418
Score = 94.0 bits (232), Expect = 9e-18
Identities = 64/157 (40%), Positives = 81/157 (51%), Gaps = 9/157 (5%)
Frame = -3
Query: 624 RECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPV 445
+ C D K+D V+IGSCT G+TED AA + G+KV L+ +P
Sbjct: 283 KNCADQKVDMVFIGSCTNGRTEDLHVAADILR--GKKVAKGLRLLV-----------IPN 329
Query: 444 PGAGGKTCAQ-----IFEEAGCDTPASPSCGACLGG----PADTYARLNEPQVCVSTTNR 292
A K C Q EAG A P+CG C+G PAD +V V+T NR
Sbjct: 330 SAAVYKECMQDGTLLALAEAGAMIEA-PNCGPCMGVHQGIPADN-------EVVVATQNR 381
Query: 291 NFPGRMGHKEGQIYLASPYTAAASALTGRVADPREFL 181
NF GRMG+ IYL+SP TAAA+AL G + DPRE +
Sbjct: 382 NFKGRMGNPTASIYLSSPATAAATALRGFITDPREVM 418
[243][TOP]
>UniRef100_A1HLS2 3-isopropylmalate dehydratase, large subunit n=1 Tax=Thermosinus
carboxydivorans Nor1 RepID=A1HLS2_9FIRM
Length = 420
Score = 94.0 bits (232), Expect = 9e-18
Identities = 55/145 (37%), Positives = 80/145 (55%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
+ +D+ ID+V IGSCT G+ ED AA + +V ++ +Q V+++
Sbjct: 285 QVRDIAIDQVVIGSCTNGRLEDLAQAAAILEGKTVHPRVRAIVIPGSQAVYLE------- 337
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
A + + F AG ++P+CG CLGG A + V+TTNRNF GRMGH +
Sbjct: 338 -AMQRGYIETFIRAGA-VVSTPTCGPCLGGYMGILAA---GERAVATTNRNFRGRMGHVD 392
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
++YLA P AAASA+ GR+A P E
Sbjct: 393 SEVYLAGPAVAAASAVLGRIAAPWE 417
[244][TOP]
>UniRef100_UPI0001979722 3-isopropylmalate dehydratase large subunit n=1 Tax=Helicobacter
cinaedi CCUG 18818 RepID=UPI0001979722
Length = 420
Score = 93.6 bits (231), Expect = 1e-17
Identities = 54/144 (37%), Positives = 80/144 (55%)
Frame = -3
Query: 612 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAG 433
++KID+V IGSCT G+ D AA + ++ ATQ ++++
Sbjct: 289 EIKIDQVVIGSCTNGRLSDMEVAANILKDKTIAKNTRCIIIPATQNIYLECI-------- 340
Query: 432 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 253
+ + F +AG ++P+CG CLGG A NE CVSTTNRNF GRMGH ++
Sbjct: 341 NRGYLETFIKAGA-VVSTPTCGPCLGGHMGILAA-NEK--CVSTTNRNFVGRMGHTTSEV 396
Query: 252 YLASPYTAAASALTGRVADPREFL 181
YL+SP AAASA+ G ++ P++ +
Sbjct: 397 YLSSPEVAAASAVRGILSSPQDVM 420
[245][TOP]
>UniRef100_C4CHB6 3-isopropylmalate dehydratase, large subunit n=1 Tax=Sphaerobacter
thermophilus DSM 20745 RepID=C4CHB6_9CHLR
Length = 418
Score = 93.6 bits (231), Expect = 1e-17
Identities = 60/143 (41%), Positives = 75/143 (52%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E D+ I +V IGSCT G+ D AK+ V ++ +Q+V
Sbjct: 284 EVGDMPIHQVVIGSCTNGRISDLREVAKILKGRQVHPNVRCIVIPGSQEV--------AK 335
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
A + A IF EAG S +CG CLGG A+ + CVSTTNRNF GRMGH+E
Sbjct: 336 QATREGLADIFLEAGAIFSTS-TCGPCLGGYMGVLAK---GERCVSTTNRNFRGRMGHRE 391
Query: 261 GQIYLASPYTAAASALTGRVADP 193
+I LA P AAASA+ GRVA P
Sbjct: 392 AEIILAGPQVAAASAVLGRVASP 414
[246][TOP]
>UniRef100_A7HBI2 3-isopropylmalate dehydratase large subunit n=1
Tax=Anaeromyxobacter sp. Fw109-5 RepID=LEUC_ANADF
Length = 478
Score = 93.6 bits (231), Expect = 1e-17
Identities = 60/143 (41%), Positives = 78/143 (54%)
Frame = -3
Query: 606 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGGK 427
K+D V++GSCT G+ ED AA++ GRKVK T +V + V A +
Sbjct: 350 KVDVVFVGSCTNGRLEDLREAARVMR--GRKVKTRTLVVAGSHAV--------KKAAEAE 399
Query: 426 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 247
+IF EAG + P C CL D L Q CVST+NRNF GR G G+ L
Sbjct: 400 GLDRIFREAGAEW-REPGCSMCLAMNGDM---LEPGQYCVSTSNRNFEGRQG-PGGRTLL 454
Query: 246 ASPYTAAASALTGRVADPREFLQ 178
ASP TAAA+A++G VADPR ++
Sbjct: 455 ASPATAAAAAVSGAVADPRRLVE 477
[247][TOP]
>UniRef100_Q2IJC2 3-isopropylmalate dehydratase large subunit n=1
Tax=Anaeromyxobacter dehalogenans 2CP-C RepID=LEUC_ANADE
Length = 480
Score = 93.6 bits (231), Expect = 1e-17
Identities = 59/143 (41%), Positives = 79/143 (55%)
Frame = -3
Query: 606 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGGK 427
K+D V+IGSCT G+ ED AA++ GRKV+ T +V + +V D A +
Sbjct: 351 KVDVVFIGSCTNGRIEDMREAARVLK--GRKVRTRTLVVPGSHRVKKDAEAEGID----- 403
Query: 426 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 247
++ EAG + P C C+ D + Q CVST+NRNF GR G G+ L
Sbjct: 404 ---RVVREAGAEW-REPGCSMCIAMNGDD---IRAGQYCVSTSNRNFEGRQG-PGGRTLL 455
Query: 246 ASPYTAAASALTGRVADPREFLQ 178
ASP TAAA+A+TG VADPR L+
Sbjct: 456 ASPLTAAAAAVTGAVADPRRVLE 478
[248][TOP]
>UniRef100_Q2NE97 LeuC1 n=1 Tax=Methanosphaera stadtmanae DSM 3091 RepID=Q2NE97_METST
Length = 418
Score = 93.2 bits (230), Expect = 2e-17
Identities = 53/145 (36%), Positives = 81/145 (55%)
Frame = -3
Query: 621 ECKDVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVP 442
E +DV+ID+V+IGSCT G+ +D AA++ V T ++ A++ ++
Sbjct: 285 EVEDVEIDQVFIGSCTNGRLKDLEQAARVLKGNKINPGVRTLVIPASRTIYKQ------- 337
Query: 441 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 262
A + IF +AG +P CG CLGG + + +V +ST+NRNF GR G E
Sbjct: 338 -ALDEGLMDIFVDAGA-LICNPCCGPCLGGHVGV---IGDGEVSLSTSNRNFKGRQGSPE 392
Query: 261 GQIYLASPYTAAASALTGRVADPRE 187
G++YL+SP AA SA+TG + P +
Sbjct: 393 GKVYLSSPIVAAESAITGHITAPEK 417
[249][TOP]
>UniRef100_A2SR25 3-isopropylmalate dehydratase, large subunit n=1
Tax=Methanocorpusculum labreanum Z RepID=A2SR25_METLZ
Length = 392
Score = 93.2 bits (230), Expect = 2e-17
Identities = 57/139 (41%), Positives = 78/139 (56%)
Frame = -3
Query: 603 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGGKT 424
+D+V+IGSCT G+ EDF AA++ V +V A++ +M V +
Sbjct: 265 VDQVFIGSCTNGRYEDFAEAAEVLGDNVFSEDVRVIMVPASKAEYMKVLKAGL------- 317
Query: 423 CAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYLA 244
+ F EAG A P CG C+GG + L +V +ST+NRNF GR G E +YL+
Sbjct: 318 -IEKFVEAGALVEA-PCCGPCMGG---AFGLLAPGEVSLSTSNRNFRGRQGSTESFVYLS 372
Query: 243 SPYTAAASALTGRVADPRE 187
SP TAAASA+TG + DPRE
Sbjct: 373 SPATAAASAITGVITDPRE 391
[250][TOP]
>UniRef100_A0B7V1 3-isopropylmalate dehydratase, large subunit n=1 Tax=Methanosaeta
thermophila PT RepID=A0B7V1_METTP
Length = 423
Score = 93.2 bits (230), Expect = 2e-17
Identities = 53/141 (37%), Positives = 79/141 (56%)
Frame = -3
Query: 609 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVTATQKVWMDVYALPVPGAGG 430
VKID++++GSCT G+ ED AA++ V ++ A++K +M +
Sbjct: 294 VKIDQIFLGSCTNGRFEDLKLAAEVMGDEPVARGVRMIVIPASRKEYMRALRAGL----- 348
Query: 429 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 250
+ F EAG SP CG C+GG ++ + +V +ST+NRNF GR G +G++Y
Sbjct: 349 ---IEKFMEAGAIVE-SPCCGPCMGG---SFGLIGPGEVSLSTSNRNFVGRQGSPKGEVY 401
Query: 249 LASPYTAAASALTGRVADPRE 187
L SP A ASA+TG + DPRE
Sbjct: 402 LCSPAVAGASAITGEITDPRE 422