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[1][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=B9DHL6_ARATH
Length = 402
Score = 274 bits (700), Expect = 4e-72
Identities = 131/136 (96%), Positives = 132/136 (97%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSE WVS+TGESDVNAVT
Sbjct: 267 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVT 326
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFPAKEVIQ TIVD ASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS
Sbjct: 327 WGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 386
Query: 211 LVDNKYINGDIFSVFA 164
LVDN YINGDIFSVFA
Sbjct: 387 LVDNNYINGDIFSVFA 402
[2][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 274 bits (700), Expect = 4e-72
Identities = 131/136 (96%), Positives = 132/136 (97%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSE WVS+TGESDVNAVT
Sbjct: 457 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVT 516
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFPAKEVIQ TIVD ASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS
Sbjct: 517 WGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 576
Query: 211 LVDNKYINGDIFSVFA 164
LVDN YINGDIFSVFA
Sbjct: 577 LVDNNYINGDIFSVFA 592
[3][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 243 bits (621), Expect = 6e-63
Identities = 114/136 (83%), Positives = 123/136 (90%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WGGP GYVYQKAYLEFFCSK+KLD +VEK KA PSITYMAVNK E+WVS+T ++DVNAVT
Sbjct: 457 WGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQADVNAVT 516
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFPAKE+IQ TIVD ASF VWKDEAFE WSRSWANLYPE DPSR LLEEVKNSYYLVS
Sbjct: 517 WGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVKNSYYLVS 576
Query: 211 LVDNKYINGDIFSVFA 164
LV+N YINGDIF+VFA
Sbjct: 577 LVENDYINGDIFAVFA 592
[4][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 229 bits (584), Expect = 1e-58
Identities = 104/136 (76%), Positives = 119/136 (87%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WGGPGGYVYQKAYLEFFCSK+KL+ LVE+ KAFP +TYMAVN+ W+S+ +DVNAVT
Sbjct: 471 WGGPGGYVYQKAYLEFFCSKEKLNALVERCKAFPLVTYMAVNRGGSWISNVALTDVNAVT 530
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFPAKE+IQ T+VD SF VWKDEAFEIWSR WA+LYPE DPSR LLEEV+NSY+LVS
Sbjct: 531 WGVFPAKEIIQPTVVDPTSFSVWKDEAFEIWSRGWASLYPEGDPSRTLLEEVQNSYFLVS 590
Query: 211 LVDNKYINGDIFSVFA 164
LVDN YI+GDIF+VFA
Sbjct: 591 LVDNDYIHGDIFAVFA 606
[5][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 226 bits (577), Expect = 7e-58
Identities = 101/135 (74%), Positives = 119/135 (88%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WGGPGGYVYQKAYLEFFCS++KL+ LV+K K PS+TYMAVNK W+S+ G +VNAVT
Sbjct: 457 WGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHPSLTYMAVNKEGTWMSNVGPGEVNAVT 516
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFPA+E+IQ T+VD +SF VWKDEAFEIWSR WA LYPEDDPSRKLLEEV+NS++LVS
Sbjct: 517 WGVFPAREIIQPTVVDPSSFMVWKDEAFEIWSRGWALLYPEDDPSRKLLEEVQNSHFLVS 576
Query: 211 LVDNKYINGDIFSVF 167
LVDN YINGD+F++F
Sbjct: 577 LVDNDYINGDLFAIF 591
[6][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 226 bits (575), Expect = 1e-57
Identities = 102/136 (75%), Positives = 118/136 (86%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WGGPGGYVYQKAYLEFFCSKDKL+ LV+K K+FP +TY+AVNK W+S+ +DVNAVT
Sbjct: 468 WGGPGGYVYQKAYLEFFCSKDKLNALVDKCKSFPFVTYIAVNKGGSWISNVALTDVNAVT 527
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP KE+IQ T+VD SF VWKDEAFEIWSR WA+LYPE DPSR LLEEV++SY+LVS
Sbjct: 528 WGVFPGKEIIQPTVVDPTSFSVWKDEAFEIWSRGWASLYPEGDPSRTLLEEVQSSYFLVS 587
Query: 211 LVDNKYINGDIFSVFA 164
LVDN YI+GDIF+VFA
Sbjct: 588 LVDNDYIHGDIFAVFA 603
[7][TOP]
>UniRef100_A9P8D1 Putative uncharacterized protein n=1 Tax=Populus trichocarpa
RepID=A9P8D1_POPTR
Length = 224
Score = 226 bits (575), Expect = 1e-57
Identities = 102/136 (75%), Positives = 118/136 (86%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WGGPGGYVYQKAYLEFFCSKDKL+ LV+K K+FP +TY+AVNK W+S+ +DVNAVT
Sbjct: 87 WGGPGGYVYQKAYLEFFCSKDKLNALVDKCKSFPFVTYIAVNKGGSWISNVALTDVNAVT 146
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP KE+IQ T+VD SF VWKDEAFEIWSR WA+LYPE DPSR LLEEV++SY+LVS
Sbjct: 147 WGVFPGKEIIQPTVVDPTSFSVWKDEAFEIWSRGWASLYPEGDPSRTLLEEVQSSYFLVS 206
Query: 211 LVDNKYINGDIFSVFA 164
LVDN YI+GDIF+VFA
Sbjct: 207 LVDNDYIHGDIFAVFA 222
[8][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 223 bits (569), Expect = 6e-57
Identities = 100/135 (74%), Positives = 118/135 (87%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WGGPGGYVYQKAYLEFFCS++KL+ LV+K K S+TYMAVNK W+S+ G +VNAVT
Sbjct: 457 WGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHTSLTYMAVNKEGTWMSNVGPGEVNAVT 516
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFPA+E+IQ T+VD +SF VWKDEAFEIWSR WA LYPEDDPSRKLLEEV+NS++LVS
Sbjct: 517 WGVFPAREIIQPTVVDPSSFMVWKDEAFEIWSRGWALLYPEDDPSRKLLEEVQNSHFLVS 576
Query: 211 LVDNKYINGDIFSVF 167
LVDN YINGD+F++F
Sbjct: 577 LVDNDYINGDLFAIF 591
[9][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 223 bits (569), Expect = 6e-57
Identities = 100/135 (74%), Positives = 118/135 (87%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WGGPGGYVYQKAYLEFFCS++KL+ LV+K K S+TYMAVNK W+S+ G +VNAVT
Sbjct: 450 WGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHTSLTYMAVNKEGTWMSNVGPGEVNAVT 509
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFPA+E+IQ T+VD +SF VWKDEAFEIWSR WA LYPEDDPSRKLLEEV+NS++LVS
Sbjct: 510 WGVFPAREIIQPTVVDPSSFMVWKDEAFEIWSRGWALLYPEDDPSRKLLEEVQNSHFLVS 569
Query: 211 LVDNKYINGDIFSVF 167
LVDN YINGD+F++F
Sbjct: 570 LVDNDYINGDLFAIF 584
[10][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 221 bits (564), Expect = 2e-56
Identities = 100/136 (73%), Positives = 117/136 (86%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WGGPGGYVYQKAY+EFFCS DKL L+EK KA P +TYMAVN+ +S+ G++DVNAVT
Sbjct: 472 WGGPGGYVYQKAYIEFFCSTDKLQALLEKCKALPQLTYMAVNRGGTLLSNVGQNDVNAVT 531
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP K++IQ T+VD ASF VWKDEAFEIW+R WA+LYPE DPSRKLLEEV++SY+LVS
Sbjct: 532 WGVFPGKQIIQPTVVDPASFSVWKDEAFEIWTRGWASLYPESDPSRKLLEEVQSSYFLVS 591
Query: 211 LVDNKYINGDIFSVFA 164
LVDN YI GDIF+VFA
Sbjct: 592 LVDNDYIQGDIFAVFA 607
[11][TOP]
>UniRef100_A6N158 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Oryza sativa
Indica Group RepID=A6N158_ORYSI
Length = 237
Score = 211 bits (536), Expect = 4e-53
Identities = 95/135 (70%), Positives = 116/135 (85%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WGGPGGYVYQKAYLEFFCSK+KLD L+EKSKAFPS+TY+AVNK + S+ + VNAVT
Sbjct: 100 WGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVT 159
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP KE++Q T+VD+ASF VWKDEAFEIWS+ WA L+PE D SR++L++V+ SY+LVS
Sbjct: 160 WGVFPGKEIVQPTVVDSASFMVWKDEAFEIWSKGWACLFPEGDSSREILDKVQKSYFLVS 219
Query: 211 LVDNKYINGDIFSVF 167
LVDN YINGD+F+ F
Sbjct: 220 LVDNDYINGDLFAAF 234
[12][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 211 bits (536), Expect = 4e-53
Identities = 95/135 (70%), Positives = 116/135 (85%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WGGPGGYVYQKAYLEFFCSK+KLD L+EKSKAFPS+TY+AVNK + S+ + VNAVT
Sbjct: 457 WGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVT 516
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP KE++Q T+VD+ASF VWKDEAFEIWS+ WA L+PE D SR++L++V+ SY+LVS
Sbjct: 517 WGVFPGKEIVQPTVVDSASFMVWKDEAFEIWSKGWACLFPEGDSSREILDKVQKSYFLVS 576
Query: 211 LVDNKYINGDIFSVF 167
LVDN YINGD+F+ F
Sbjct: 577 LVDNDYINGDLFAAF 591
[13][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 210 bits (535), Expect = 5e-53
Identities = 95/135 (70%), Positives = 116/135 (85%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WGGPGGYVYQKAY+EFFC+K+KL L+EKSKAFPS+TY+AVNK + +S+ + VNAVT
Sbjct: 445 WGGPGGYVYQKAYVEFFCAKEKLGQLIEKSKAFPSLTYIAVNKEGESISNIPANAVNAVT 504
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP KE+IQ T+VD+ASF VWKDEAFEIWSR WA L+PE D SR+LLE+++ SYYLVS
Sbjct: 505 WGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRGWACLFPEGDSSRELLEQIQKSYYLVS 564
Query: 211 LVDNKYINGDIFSVF 167
LVDN YI+GD+F+ F
Sbjct: 565 LVDNDYISGDLFAAF 579
[14][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 208 bits (530), Expect = 2e-52
Identities = 95/135 (70%), Positives = 113/135 (83%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WGGPGGYVYQKAYLEFFC+K+KLD L+EK KAFPS+TY+AVNK + S+ + VNAVT
Sbjct: 457 WGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKAFPSLTYIAVNKDGESFSNIAPNAVNAVT 516
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP KE+IQ T+VD ASF VWKDEAFEIW+R WA L+PE D SR+LLE+V+ SYYLVS
Sbjct: 517 WGVFPGKEIIQPTVVDPASFMVWKDEAFEIWTRGWACLFPEGDSSRELLEKVQKSYYLVS 576
Query: 211 LVDNKYINGDIFSVF 167
LVDN Y+ GD+F+ F
Sbjct: 577 LVDNDYVQGDLFAAF 591
[15][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 208 bits (530), Expect = 2e-52
Identities = 93/136 (68%), Positives = 113/136 (83%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WGGPGGYVYQKAY+EFFCS +KL ++EK+K PS+TY+AVN + S+ G + VNAVT
Sbjct: 457 WGGPGGYVYQKAYVEFFCSPEKLQAVIEKAKTSPSLTYIAVNAKGETKSNVGPTSVNAVT 516
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFPAKEVIQ T+VD SF VWKDEAF+ W + WA+LYPEDD SRK+L E+K+SY+LVS
Sbjct: 517 WGVFPAKEVIQPTVVDPVSFMVWKDEAFQAWDQEWASLYPEDDASRKILSEIKSSYFLVS 576
Query: 211 LVDNKYINGDIFSVFA 164
+VDN YINGD+FSVFA
Sbjct: 577 MVDNDYINGDLFSVFA 592
[16][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 205 bits (522), Expect = 2e-51
Identities = 93/135 (68%), Positives = 112/135 (82%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WGG GYVYQKAY+EFFCS +KL+ LVEK+K P +TY+AVNK ++ G +DVNAVT
Sbjct: 457 WGGAAGYVYQKAYVEFFCSPEKLNELVEKAKNLPFVTYIAVNKKGATAANIGPTDVNAVT 516
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFPAKEVIQ T+VD SF VWKDEAF+ W + WA+LYP+ DPSRK+LEEV+NSYYLVS
Sbjct: 517 WGVFPAKEVIQPTVVDPVSFMVWKDEAFQAWEQEWASLYPDGDPSRKILEEVQNSYYLVS 576
Query: 211 LVDNKYINGDIFSVF 167
+VDN YI+GD+FSVF
Sbjct: 577 VVDNDYIHGDLFSVF 591
[17][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 205 bits (521), Expect = 2e-51
Identities = 92/135 (68%), Positives = 112/135 (82%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WGGPGGYVYQKAYLEFFC+K+KLD L+EK KAFPS+TY+AVNK + S+ + VNAVT
Sbjct: 457 WGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKAFPSLTYIAVNKDGETFSNISPNAVNAVT 516
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP KE+IQ T+VD ASF VWKDEAFEIW+R W ++PE D SR+LLE+V+ +YYLVS
Sbjct: 517 WGVFPGKEIIQPTVVDHASFMVWKDEAFEIWTRGWGCMFPEGDSSRELLEKVQKTYYLVS 576
Query: 211 LVDNKYINGDIFSVF 167
LVDN Y+ GD+F+ F
Sbjct: 577 LVDNDYVQGDLFAAF 591
[18][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 198 bits (503), Expect = 3e-49
Identities = 89/136 (65%), Positives = 111/136 (81%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WGGPGGYVYQKAY+EFFCS +KL ++EK+K+ PS+T++AVN + S+ G + VNAVT
Sbjct: 457 WGGPGGYVYQKAYVEFFCSPEKLQAVIEKAKSNPSLTFIAVNAKGETQSNIGPNCVNAVT 516
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFPAKEVIQ T+VD SF VWKDEAF+ W WA LY E+D SRK+L E+K+SY+LVS
Sbjct: 517 WGVFPAKEVIQPTVVDPVSFMVWKDEAFQTWDHEWAALYSEEDSSRKILSEIKDSYFLVS 576
Query: 211 LVDNKYINGDIFSVFA 164
+VDN YINGD+F+VFA
Sbjct: 577 MVDNDYINGDLFAVFA 592
[19][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 176 bits (446), Expect = 1e-42
Identities = 79/112 (70%), Positives = 96/112 (85%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WGGPGGYVYQKAYLEFFCSK+KLD L+EKSKAFPS+TY+AVNK + S+ + VNAVT
Sbjct: 457 WGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVT 516
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
WGVFP KE++Q T+VD+ASF VWKDEAFEIWS+ WA L+PE D SR++L++V
Sbjct: 517 WGVFPGKEIVQPTVVDSASFMVWKDEAFEIWSKGWACLFPEGDSSREILDKV 568
[20][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 158 bits (399), Expect = 3e-37
Identities = 76/134 (56%), Positives = 91/134 (67%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WGGPGGYVY KAY+EFFCS + TL K A PSITY+A + + VNAVT
Sbjct: 458 WGGPGGYVYGKAYVEFFCSPEAWATLRAKLDAAPSITYLATTAAGSPAGNMAPDAVNAVT 517
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP KEVIQ T+V A SF VWKDEAFE+W+ W LY E +R LL +K+S+ LVS
Sbjct: 518 WGVFPGKEVIQPTVVCAPSFAVWKDEAFELWTSEWGALYEEGSAARDLLAGIKDSWVLVS 577
Query: 211 LVDNKYINGDIFSV 170
+VDN Y+ GD+F V
Sbjct: 578 VVDNDYVAGDLFGV 591
[21][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 148 bits (374), Expect = 3e-34
Identities = 70/135 (51%), Positives = 89/135 (65%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WGG G VY+KAY+EFF S + L+E K P ITY AVN+ K S T NAVT
Sbjct: 465 WGGKNGIVYKKAYIEFFASPENTLKLIEYFKKCPMITYHAVNR--KGDSKTNTKGTNAVT 522
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+FP KE+IQ T+VD SF VWKDEAF +W W++ Y SR LL+ + N+YYL++
Sbjct: 523 WGIFPGKEIIQPTVVDHNSFMVWKDEAFALWETQWSSTYSPSSTSRTLLDSMINNYYLIN 582
Query: 211 LVDNKYINGDIFSVF 167
+VDN +ING+IF F
Sbjct: 583 IVDNNFINGNIFQSF 597
[22][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 147 bits (372), Expect = 4e-34
Identities = 74/136 (54%), Positives = 92/136 (67%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG PGGYVYQKAYLEFF S D L L+ + + P ITY AVNK ++T NAVT
Sbjct: 452 WGPPGGYVYQKAYLEFFVSPDLLSPLIRRIEKDPRITYYAVNKQGDLRTNTHSESPNAVT 511
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP KE++Q TIV+A SF WKDEAFE+ WA+LYP + PSRKL+ + N+ YLV+
Sbjct: 512 WGVFPGKEIVQPTIVEAVSFIAWKDEAFEL-GLQWAHLYPAESPSRKLITDTMNTSYLVN 570
Query: 211 LVDNKYING-DIFSVF 167
+V N + +G IF F
Sbjct: 571 IVANDFRDGMSIFEPF 586
[23][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 145 bits (366), Expect = 2e-33
Identities = 67/130 (51%), Positives = 89/130 (68%), Gaps = 1/130 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKW-VSSTGESDVNAV 395
WGGP GYVYQKAYLEFF S ++ TL+E FP I Y A++ SE VS++ AV
Sbjct: 484 WGGPNGYVYQKAYLEFFISAERFKTLLEVLPNFPMINYHALDLSESINVSNSDHHQPIAV 543
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWGVFP +E++Q T+VD SF WKDEAF +W+ WANLYPE+ SR+++ ++ LV
Sbjct: 544 TWGVFPGREILQPTVVDPTSFSYWKDEAFALWTNQWANLYPEESKSRQVITAAVRNFVLV 603
Query: 214 SLVDNKYING 185
++VDN +I G
Sbjct: 604 NMVDNDFIQG 613
[24][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 144 bits (362), Expect = 6e-33
Identities = 63/131 (48%), Positives = 90/131 (68%), Gaps = 1/131 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVN-AV 395
WGG GGY+YQKAYLEFF S + + L+++ K +P + Y VN + + +S AV
Sbjct: 445 WGGEGGYIYQKAYLEFFASPEVVYILLQELKNYPQVNYHVVNNHDTVDITNCDSQTPVAV 504
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWGVFP +E++Q T+VD SFK+WKDEAF +W + W+ LY ED SR ++ ++ N+Y LV
Sbjct: 505 TWGVFPGREIVQPTVVDPISFKIWKDEAFSLWEQQWSRLYTEDSKSRAIINKIMNTYCLV 564
Query: 214 SLVDNKYINGD 182
+LVDN +I G+
Sbjct: 565 NLVDNDFIKGN 575
[25][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 140 bits (353), Expect = 7e-32
Identities = 72/136 (52%), Positives = 90/136 (66%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLEFF S + LD L+ + +A P ITY AVN ++T NAVT
Sbjct: 464 WGPKNGYVYQKAYLEFFVSPEDLDALIARIEADPQITYHAVNSQGDMRTNTNSEAPNAVT 523
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP E+IQ TIV++ SF WKDEA+EI R+WA +Y PSRK LE++ NSY+LV+
Sbjct: 524 WGVFPHCEIIQPTIVESISFLAWKDEAYEI-GRNWAKVYEPTSPSRKFLEDMFNSYFLVN 582
Query: 211 LVDNKY-INGDIFSVF 167
+V N + N IF F
Sbjct: 583 VVHNDFKANDSIFEPF 598
[26][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 138 bits (348), Expect = 3e-31
Identities = 67/138 (48%), Positives = 95/138 (68%), Gaps = 5/138 (3%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVE--KSKAFPSITYMAVNKSEKWVSST--GESDV 404
WG GG+VYQKAY+EFFC + +L+ L+ +++ + SI+YMAV V S + V
Sbjct: 431 WGPAGGFVYQKAYVEFFCPEGQLEQLIRGIEAEKYDSISYMAVTADGSKVRSNIPPQGQV 490
Query: 403 NAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDD-PSRKLLEEVKNS 227
NAVTWGVFP E+IQ T+VD SF WKDEAF +W+ W ++YPEDD SR++L ++
Sbjct: 491 NAVTWGVFPNSEIIQPTVVDVTSFMAWKDEAFALWN-EWMDVYPEDDHQSRQVLNFIRQH 549
Query: 226 YYLVSLVDNKYINGDIFS 173
Y+L ++VDN ++ GD+FS
Sbjct: 550 YFLCTVVDNDFVAGDLFS 567
[27][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 138 bits (348), Expect = 3e-31
Identities = 67/138 (48%), Positives = 95/138 (68%), Gaps = 5/138 (3%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVE--KSKAFPSITYMAVNKSEKWVSST--GESDV 404
WG GG+VYQKAY+EFFC + +L+ L+ +++ + SI+YMAV V S + V
Sbjct: 410 WGPAGGFVYQKAYVEFFCPEGQLEQLIRGIEAEKYDSISYMAVTADGSKVRSNIPPQGQV 469
Query: 403 NAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDD-PSRKLLEEVKNS 227
NAVTWGVFP E+IQ T+VD SF WKDEAF +W+ W ++YPEDD SR++L ++
Sbjct: 470 NAVTWGVFPNSEIIQPTVVDVTSFMAWKDEAFALWN-EWMDVYPEDDHQSRQVLNFIRQH 528
Query: 226 YYLVSLVDNKYINGDIFS 173
Y+L ++VDN ++ GD+FS
Sbjct: 529 YFLCTVVDNDFVAGDLFS 546
[28][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 135 bits (341), Expect = 2e-30
Identities = 58/127 (45%), Positives = 86/127 (67%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S + + L++ K + P + Y VN + +++ + NAV
Sbjct: 500 WGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYQIVNVQGRNITNAHDMQPNAV 559
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W WA LY ++ PSR +++ + ++Y+LV
Sbjct: 560 TWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLV 619
Query: 214 SLVDNKY 194
+LVDN +
Sbjct: 620 NLVDNDF 626
[29][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 135 bits (340), Expect = 2e-30
Identities = 60/132 (45%), Positives = 88/132 (66%), Gaps = 1/132 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVN-KSEKWVSSTGESDVNAV 395
WG PGGYV+QKAYLEFF S++ + L + +P++ Y + + + ++ + AV
Sbjct: 489 WGTPGGYVFQKAYLEFFTSRENVQALFKVLPKYPNVNYHIIKFEGDDDYTNCDQQQPIAV 548
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWGVFP KE+IQ T+VD SFK WKDEAF +W+ W LY ED SR+L++ + +++YLV
Sbjct: 549 TWGVFPGKEIIQPTVVDPVSFKFWKDEAFTLWTEYWGQLYAEDSKSRELIQHIHDTWYLV 608
Query: 214 SLVDNKYINGDI 179
+LVDN + +I
Sbjct: 609 NLVDNDFPRDNI 620
[30][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 134 bits (337), Expect = 5e-30
Identities = 59/127 (46%), Positives = 85/127 (66%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSEKWVSSTGESDVNAV 395
WG GYV+QKAYLEFF S + + L++ K + P + Y VN + +++ + NAV
Sbjct: 494 WGPSRGYVFQKAYLEFFTSSEMVSALIKVLKRYEPRVNYHIVNVHGQNITNAADLQPNAV 553
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W WA LY E+ PSR +++ + ++YYLV
Sbjct: 554 TWGIFPGREIIQPTVVDPVSFVYWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLV 613
Query: 214 SLVDNKY 194
+LVDN +
Sbjct: 614 NLVDNDF 620
[31][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 133 bits (334), Expect = 1e-29
Identities = 58/127 (45%), Positives = 86/127 (67%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S + ++ L++ K + + Y VN + +++ E NAV
Sbjct: 494 WGPSGGYVFQKAYLEFFTSSETVEALLQVLKKYELRVNYHIVNVKGENITNAPELQPNAV 553
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV
Sbjct: 554 TWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYHLV 613
Query: 214 SLVDNKY 194
+LVDN++
Sbjct: 614 NLVDNEF 620
[32][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 132 bits (333), Expect = 1e-29
Identities = 56/128 (43%), Positives = 88/128 (68%), Gaps = 1/128 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S++ ++ L++ K + + Y V+ + +++ E NAV
Sbjct: 505 WGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAV 564
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E++Q T+VD SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV
Sbjct: 565 TWGIFPGREIVQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLV 624
Query: 214 SLVDNKYI 191
+LVDN+++
Sbjct: 625 NLVDNEFL 632
[33][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 132 bits (333), Expect = 1e-29
Identities = 56/128 (43%), Positives = 88/128 (68%), Gaps = 1/128 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S++ ++ L++ K + + Y V+ + +++ E NAV
Sbjct: 540 WGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAV 599
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E++Q T+VD SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV
Sbjct: 600 TWGIFPGREIVQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLV 659
Query: 214 SLVDNKYI 191
+LVDN+++
Sbjct: 660 NLVDNEFL 667
[34][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 132 bits (332), Expect = 2e-29
Identities = 61/131 (46%), Positives = 82/131 (62%), Gaps = 1/131 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGES-DVNAV 395
WGG GGY+YQKAYLEFF K +D L+E P + Y ++ + + + AV
Sbjct: 478 WGGAGGYIYQKAYLEFFMHKKNVDFLLEVLNDNPRVNYHIIDSHGCYDKTNADRYSPIAV 537
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWGVFP KE+IQ T+VD SF WKDEAF +W W +LY + S K+++ + N +YLV
Sbjct: 538 TWGVFPGKEIIQPTVVDPISFNFWKDEAFSLWIEKWQSLYEPESFSAKIIQSIYNDFYLV 597
Query: 214 SLVDNKYINGD 182
+LVDN YI G+
Sbjct: 598 NLVDNDYIKGN 608
[35][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 132 bits (332), Expect = 2e-29
Identities = 58/127 (45%), Positives = 85/127 (66%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S++ + L++ K + + Y VN + +++ E NAV
Sbjct: 523 WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV 582
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV
Sbjct: 583 TWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYEEESPSRTIIQYIHDNYFLV 642
Query: 214 SLVDNKY 194
+LVDN +
Sbjct: 643 NLVDNDF 649
[36][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 132 bits (332), Expect = 2e-29
Identities = 58/127 (45%), Positives = 85/127 (66%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S++ + L++ K + + Y VN + +++ E NAV
Sbjct: 541 WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV 600
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV
Sbjct: 601 TWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYEEESPSRTIIQYIHDNYFLV 660
Query: 214 SLVDNKY 194
+LVDN +
Sbjct: 661 NLVDNDF 667
[37][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 132 bits (332), Expect = 2e-29
Identities = 58/127 (45%), Positives = 85/127 (66%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S++ + L++ K + + Y VN + +++ E NAV
Sbjct: 523 WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV 582
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV
Sbjct: 583 TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYIHDNYFLV 642
Query: 214 SLVDNKY 194
+LVDN +
Sbjct: 643 NLVDNDF 649
[38][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 132 bits (332), Expect = 2e-29
Identities = 58/127 (45%), Positives = 85/127 (66%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S++ + L++ K + + Y VN + +++ E NAV
Sbjct: 541 WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV 600
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV
Sbjct: 601 TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYIHDNYFLV 660
Query: 214 SLVDNKY 194
+LVDN +
Sbjct: 661 NLVDNDF 667
[39][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 132 bits (332), Expect = 2e-29
Identities = 57/127 (44%), Positives = 87/127 (68%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S++ ++ L++ K + + Y V+ + +++ E NAV
Sbjct: 499 WGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAV 558
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV
Sbjct: 559 TWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLV 618
Query: 214 SLVDNKY 194
+LVDN++
Sbjct: 619 NLVDNEF 625
[40][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 132 bits (332), Expect = 2e-29
Identities = 58/127 (45%), Positives = 85/127 (66%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSEKWVSSTGESDVNAV 395
WG GYV+QKAYLEFF S + + L++ K + P + Y VN + +++ + +AV
Sbjct: 494 WGPSRGYVFQKAYLEFFTSSEMVTALIKVLKRYEPRVNYHIVNVHGQNITNAADLQPSAV 553
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W WA LY E+ PSR +++ + ++YYLV
Sbjct: 554 TWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLV 613
Query: 214 SLVDNKY 194
+LVDN +
Sbjct: 614 NLVDNDF 620
[41][TOP]
>UniRef100_Q497H7 Mthfr protein (Fragment) n=2 Tax=Mus musculus RepID=Q497H7_MOUSE
Length = 166
Score = 132 bits (332), Expect = 2e-29
Identities = 57/127 (44%), Positives = 87/127 (68%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S++ ++ L++ K + + Y V+ + +++ E NAV
Sbjct: 11 WGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAV 70
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV
Sbjct: 71 TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLV 130
Query: 214 SLVDNKY 194
+LVDN++
Sbjct: 131 NLVDNEF 137
[42][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 132 bits (332), Expect = 2e-29
Identities = 57/127 (44%), Positives = 87/127 (68%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S++ ++ L++ K + + Y V+ + +++ E NAV
Sbjct: 540 WGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAV 599
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV
Sbjct: 600 TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLV 659
Query: 214 SLVDNKY 194
+LVDN++
Sbjct: 660 NLVDNEF 666
[43][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 132 bits (332), Expect = 2e-29
Identities = 57/127 (44%), Positives = 87/127 (68%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S++ ++ L++ K + + Y V+ + +++ E NAV
Sbjct: 540 WGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAV 599
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV
Sbjct: 600 TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLV 659
Query: 214 SLVDNKY 194
+LVDN++
Sbjct: 660 NLVDNEF 666
[44][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S5W8_NEMVE
Length = 619
Score = 132 bits (332), Expect = 2e-29
Identities = 62/131 (47%), Positives = 83/131 (63%), Gaps = 1/131 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKS-EKWVSSTGESDVNAV 395
WG PGGYV+QKAYLEFF ++ L + K I + VN S E ++ NAV
Sbjct: 474 WGKPGGYVFQKAYLEFFAREEIALELYHQLKDGTRINFHLVNSSGESDFTNANMYSPNAV 533
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWGVFP E++Q T+VD +F WKDEAF +W + W LYPE SR +++ + +SYYLV
Sbjct: 534 TWGVFPGSEILQPTVVDPIAFHYWKDEAFGLWKQQWGRLYPEGSRSRDIIDSIYDSYYLV 593
Query: 214 SLVDNKYINGD 182
+LVDN Y+ G+
Sbjct: 594 NLVDNDYVGGN 604
[45][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 132 bits (332), Expect = 2e-29
Identities = 58/127 (45%), Positives = 85/127 (66%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S++ + L++ K + + Y VN + +++ E NAV
Sbjct: 500 WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV 559
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV
Sbjct: 560 TWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYEEESPSRTIIQYIHDNYFLV 619
Query: 214 SLVDNKY 194
+LVDN +
Sbjct: 620 NLVDNDF 626
[46][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 132 bits (332), Expect = 2e-29
Identities = 57/127 (44%), Positives = 87/127 (68%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S++ ++ L++ K + + Y V+ + +++ E NAV
Sbjct: 499 WGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAV 558
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV
Sbjct: 559 TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLV 618
Query: 214 SLVDNKY 194
+LVDN++
Sbjct: 619 NLVDNEF 625
[47][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 132 bits (332), Expect = 2e-29
Identities = 58/127 (45%), Positives = 85/127 (66%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S++ + L++ K + + Y VN + +++ E NAV
Sbjct: 500 WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV 559
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV
Sbjct: 560 TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYIHDNYFLV 619
Query: 214 SLVDNKY 194
+LVDN +
Sbjct: 620 NLVDNDF 626
[48][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 132 bits (332), Expect = 2e-29
Identities = 57/127 (44%), Positives = 87/127 (68%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S++ ++ L++ K + + Y V+ + +++ E NAV
Sbjct: 499 WGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAV 558
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV
Sbjct: 559 TWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLV 618
Query: 214 SLVDNKY 194
+LVDN++
Sbjct: 619 NLVDNEF 625
[49][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 131 bits (330), Expect = 3e-29
Identities = 59/127 (46%), Positives = 85/127 (66%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S + + L++ K + + Y VN + +++ + NAV
Sbjct: 502 WGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVQGQNITNAPDLQPNAV 561
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W WA LY E+ PSR +++ + ++YYLV
Sbjct: 562 TWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLV 621
Query: 214 SLVDNKY 194
+LVDN +
Sbjct: 622 NLVDNDF 628
[50][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
RepID=UPI0000E814FF
Length = 508
Score = 131 bits (330), Expect = 3e-29
Identities = 59/127 (46%), Positives = 85/127 (66%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S + + L++ K + + Y VN + +++ + NAV
Sbjct: 359 WGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYELRVNYHIVNVKGQNITNAPDLQPNAV 418
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W WA LY E+ PSR +++ + ++YYLV
Sbjct: 419 TWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLV 478
Query: 214 SLVDNKY 194
+LVDN +
Sbjct: 479 NLVDNDF 485
[51][TOP]
>UniRef100_UPI0000ECA34F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Gallus
gallus RepID=UPI0000ECA34F
Length = 640
Score = 131 bits (330), Expect = 3e-29
Identities = 59/127 (46%), Positives = 85/127 (66%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S + + L++ K + + Y VN + +++ + NAV
Sbjct: 491 WGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYELRVNYHIVNVKGQNITNAPDLQPNAV 550
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W WA LY E+ PSR +++ + ++YYLV
Sbjct: 551 TWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLV 610
Query: 214 SLVDNKY 194
+LVDN +
Sbjct: 611 NLVDNDF 617
[52][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 131 bits (329), Expect = 4e-29
Identities = 57/127 (44%), Positives = 86/127 (67%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S++ ++ L++ K + + Y V+ + +++ E NAV
Sbjct: 499 WGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAV 558
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV
Sbjct: 559 TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLV 618
Query: 214 SLVDNKY 194
+LVDN +
Sbjct: 619 NLVDNDF 625
[53][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Canis lupus familiaris RepID=UPI00005A03BF
Length = 780
Score = 131 bits (329), Expect = 4e-29
Identities = 57/127 (44%), Positives = 86/127 (67%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S++ + L++ K + + Y V+ + +++ E NAV
Sbjct: 625 WGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAV 684
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV
Sbjct: 685 TWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLV 744
Query: 214 SLVDNKY 194
+LVDN++
Sbjct: 745 NLVDNEF 751
[54][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 131 bits (329), Expect = 4e-29
Identities = 57/127 (44%), Positives = 85/127 (66%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYVYQKAYLEFF S + + L++ K + P + Y VN + +++ + NAV
Sbjct: 504 WGPAGGYVYQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPNAV 563
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+F +E++Q T+VD SF WKDEAF +W WA LY ++ PSR +++ + ++Y+LV
Sbjct: 564 TWGIFAGREIVQPTVVDPVSFMSWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLV 623
Query: 214 SLVDNKY 194
+LVDN +
Sbjct: 624 NLVDNDF 630
[55][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 131 bits (329), Expect = 4e-29
Identities = 57/127 (44%), Positives = 86/127 (67%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S++ + L++ K + + Y V+ + +++ E NAV
Sbjct: 541 WGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAV 600
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV
Sbjct: 601 TWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLV 660
Query: 214 SLVDNKY 194
+LVDN++
Sbjct: 661 NLVDNEF 667
[56][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 130 bits (327), Expect = 7e-29
Identities = 57/127 (44%), Positives = 86/127 (67%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S++ ++ L++ K + + Y V+ + +++ E NAV
Sbjct: 540 WGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAV 599
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF W W LY E+ PSR +++ + ++Y+LV
Sbjct: 600 TWGIFPGREIIQPTVVDPISFMFWKDEAFAPWIEQWGKLYEEESPSRMIIQYIHDNYFLV 659
Query: 214 SLVDNKY 194
+LVDN++
Sbjct: 660 NLVDNEF 666
[57][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 130 bits (326), Expect = 9e-29
Identities = 57/127 (44%), Positives = 85/127 (66%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S + + L++ K + + Y VN + +++ + NAV
Sbjct: 497 WGPSGGYVFQKAYLEFFTSSETVAALLKVLKKYELRVNYHIVNVKGENITNAPDMQPNAV 556
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWG+FP +E+IQ T+VD SF WKDEAF +W W LY E+ PSR +++ + ++Y+LV
Sbjct: 557 TWGIFPGREIIQPTVVDPVSFMSWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYHLV 616
Query: 214 SLVDNKY 194
+LVDN++
Sbjct: 617 NLVDNEF 623
[58][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 129 bits (324), Expect = 2e-28
Identities = 59/129 (45%), Positives = 82/129 (63%), Gaps = 1/129 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGE-SDVNAV 395
WGGPGGY+YQKAY E FCS + + LV K S+ AVN + + E V A+
Sbjct: 487 WGGPGGYIYQKAYCECFCSPENMRCLVNMVKQNQSMNVYAVNNAGNCIQEGTELGGVTAL 546
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWGVFP +E++Q TI D F VW +EAF +W+ W+NLY D S L+E ++++YYL
Sbjct: 547 TWGVFPNREILQPTIFDPRIFLVWAEEAFSLWTSMWSNLYDYDSDSFDLIETIRDTYYLC 606
Query: 214 SLVDNKYIN 188
+++DN YI+
Sbjct: 607 AIIDNDYIS 615
[59][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 129 bits (324), Expect = 2e-28
Identities = 61/128 (47%), Positives = 90/128 (70%), Gaps = 2/128 (1%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS--ITYMAVNKSEKWVSSTGESDVNA 398
WG GGYV+QKA++EFF ++D+++ L EK + IT A N+ + ++T + VNA
Sbjct: 492 WGPRGGYVFQKAFVEFFVTEDEVNRLKEKVEREGKGLITMYAANRKGDFKTNTDKDSVNA 551
Query: 397 VTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYL 218
VTWGVFP +E+ Q+TI++ SF WK+EAF+IW+ W+ LYP + PSRKLLE + N ++L
Sbjct: 552 VTWGVFPGQEIAQSTIIEETSFLAWKEEAFDIWA-EWSLLYPRNTPSRKLLEGIANEWWL 610
Query: 217 VSLVDNKY 194
VSL+ + Y
Sbjct: 611 VSLIHHDY 618
[60][TOP]
>UniRef100_A8Q9P3 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8Q9P3_MALGO
Length = 515
Score = 129 bits (323), Expect = 2e-28
Identities = 64/126 (50%), Positives = 83/126 (65%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLEFF S +LD L+ + A P ITY AVN ++T NAVT
Sbjct: 373 WGPKHGYVYQKAYLEFFVSPQQLDELIARFDAHPQITYHAVNAQGDMRTNTTSDAPNAVT 432
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG FP E++Q TIV++ SF WKDEA+EI R WA Y + P+R+LLE V ++Y+LV+
Sbjct: 433 WGCFPHCEILQPTIVESMSFLAWKDEAYEI-GRRWAAFYEPESPTRRLLEHVFDTYFLVN 491
Query: 211 LVDNKY 194
+V N +
Sbjct: 492 VVHNDF 497
[61][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 126 bits (316), Expect = 1e-27
Identities = 66/136 (48%), Positives = 86/136 (63%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLEFF L L++ + +ITY +NK ++T NAVT
Sbjct: 408 WGPSNGYVYQKAYLEFFVDPALLQLLLKHLERDTNITYHVINKRGDLQTNTHSEGPNAVT 467
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP KE+IQ TIV+A SF WKDEA+E+ ++ WA LY D PS+KL+ + +Y LV+
Sbjct: 468 WGVFPGKEIIQPTIVEAISFMAWKDEAYELGAQ-WARLYEHDSPSQKLILNLMENYALVN 526
Query: 211 LVDNKYINGD-IFSVF 167
+V N + N D IF F
Sbjct: 527 VVHNDFHNPDAIFEPF 542
[62][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 125 bits (314), Expect = 2e-27
Identities = 60/136 (44%), Positives = 90/136 (66%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLE + +D L+ + + P +TY VNK+ + + + E NAVT
Sbjct: 448 WGPRNGYVYQKAYLELLVPPEHVDELLRRIEKNPDLTYYCVNKTGELKARSDEGP-NAVT 506
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +KE+IQ TIV++ SF WKDEA+++ WA +P D PSRKL++ V + +Y+++
Sbjct: 507 WGIFASKEIIQPTIVESVSFMAWKDEAYQL-GEDWAKCHPADSPSRKLIQRVMDEWYILN 565
Query: 211 LVDNKY-INGDIFSVF 167
+V+N + N DIF +F
Sbjct: 566 IVNNDFHKNDDIFRLF 581
[63][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 125 bits (313), Expect = 3e-27
Identities = 60/128 (46%), Positives = 82/128 (64%), Gaps = 2/128 (1%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTL-VEKSKAFPSITYMAVNKSEKWVSSTGE-SDVNA 398
WG GGY+ QKAYLEFF +K + L K P + Y +NK + + S+ NA
Sbjct: 473 WGDKGGYISQKAYLEFFINKHYAEALKTVLPKYHPRVNYHMINKCGTTDHTNADRSNPNA 532
Query: 397 VTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYL 218
VTWG+F KE+IQ T+VD SF VWKDEAF +W WA+LY + SR+++ ++ ++YYL
Sbjct: 533 VTWGIFAGKEIIQPTVVDPVSFIVWKDEAFGLWHERWASLYEKGSKSREIINDIADNYYL 592
Query: 217 VSLVDNKY 194
V+LVDN Y
Sbjct: 593 VNLVDNDY 600
[64][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 125 bits (313), Expect = 3e-27
Identities = 64/136 (47%), Positives = 87/136 (63%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLEFF + L+ L+ + +ITY +NK ++T NAVT
Sbjct: 448 WGPSNGYVYQKAYLEFFVNPTLLNLLLTHIERDSNITYYVINKRGDLRTNTHSDGPNAVT 507
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP KE++Q TIV+A SF WKDEAFE+ + WA LY + PS+KL+ E+ ++ +LV+
Sbjct: 508 WGVFPGKEIVQPTIVEAVSFMAWKDEAFEL-GQQWAKLYEANSPSQKLITELMDTCFLVN 566
Query: 211 LVDNKYINGD-IFSVF 167
+V N + D IF F
Sbjct: 567 VVHNDFHEPDAIFKPF 582
[65][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 124 bits (311), Expect = 5e-27
Identities = 61/130 (46%), Positives = 82/130 (63%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLE S + + ++ + P +TY AV KS ++ NAVT
Sbjct: 447 WGPSKGYVYQKAYLELLVSPEVYPEIKKRIENHPDLTYHAVTKSGMLETNAPSDAPNAVT 506
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP KE++Q TIV+ SF WKDEAF++ S WA Y D PSR LLE++ S+YLV+
Sbjct: 507 WGVFPGKEIVQPTIVERISFLAWKDEAFQLGS-DWARCYEADTPSRLLLEDIMKSWYLVN 565
Query: 211 LVDNKYINGD 182
+V+N + G+
Sbjct: 566 IVNNDFHQGE 575
[66][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 123 bits (309), Expect = 9e-27
Identities = 61/135 (45%), Positives = 84/135 (62%), Gaps = 1/135 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLE S + + + ++ P +TY AV KS ++ NAVT
Sbjct: 447 WGPANGYVYQKAYLEMLISPELFPQIKSRIESHPDLTYHAVTKSGNLHTNAQFEGPNAVT 506
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP KE++Q TIV+ SF WKDEAF++ WA Y PSR +L+E+ N++YLV+
Sbjct: 507 WGVFPGKEIVQPTIVERISFLAWKDEAFQL-GMEWARCYETGTPSRSILDEIMNTWYLVN 565
Query: 211 LVDNKYINGD-IFSV 170
+V+N + G+ IF V
Sbjct: 566 IVNNDFHRGETIFEV 580
[67][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 122 bits (307), Expect = 1e-26
Identities = 58/126 (46%), Positives = 79/126 (62%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLE S + + + + P ITY AV KS ++ NAVT
Sbjct: 447 WGPANGYVYQKAYLELLVSPELFPEIKRRIEDHPDITYYAVTKSGNLHTNAPSEGPNAVT 506
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP KE++Q TIV++ SF WKDEAF++ WA Y D PSR L+EE+ + +YL++
Sbjct: 507 WGVFPGKEIVQPTIVESISFLAWKDEAFQL-GLEWARCYDADTPSRLLIEEIMDKWYLIN 565
Query: 211 LVDNKY 194
+V+N +
Sbjct: 566 IVNNDF 571
[68][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 121 bits (304), Expect = 3e-26
Identities = 58/136 (42%), Positives = 90/136 (66%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG G+VYQKAYLE + ++ L+ + + P +TY +NK+ + + + E NAVT
Sbjct: 448 WGPRNGFVYQKAYLELLVPPEHVEELLRRIEKNPDLTYYCINKTGELRARSDEGP-NAVT 506
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +KE+IQ TIV++ SF WKDEA+++ WA +P D PSRKLL+ V + +Y+++
Sbjct: 507 WGIFASKEIIQPTIVESVSFMAWKDEAYQL-GDDWAKCHPADSPSRKLLQRVMDEWYILN 565
Query: 211 LVDNKY-INGDIFSVF 167
+V+N + N DIF +F
Sbjct: 566 IVNNDFHKNDDIFRLF 581
[69][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 120 bits (301), Expect = 7e-26
Identities = 59/136 (43%), Positives = 89/136 (65%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLE S +D ++ + + P +TY VNK + ++T +S NAVT
Sbjct: 447 WGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKKGELRTNTTDSP-NAVT 505
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +KE+IQ TIV+ SF WKDEA+ + WA + PSR+++++V +S+YLV+
Sbjct: 506 WGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHVASSPSRRIIQQVMDSWYLVN 564
Query: 211 LVDNKY-INGDIFSVF 167
+V+N + DIF++F
Sbjct: 565 IVNNDFHKTHDIFNIF 580
[70][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 120 bits (300), Expect = 1e-25
Identities = 58/126 (46%), Positives = 77/126 (61%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQK+YLE D ++ + + P +TY AV K + S+ NAVT
Sbjct: 447 WGPDNGYVYQKSYLELLVHPGVFDKMISRIENHPDLTYYAVTKDGELRSNVTSDGPNAVT 506
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP KE++Q TIV++ SF WKDEAF + WA+ Y PSR LLE V N +YLV+
Sbjct: 507 WGVFPGKEIVQPTIVESISFLAWKDEAFRL-GVDWAHCYDISSPSRALLEGVMNDWYLVN 565
Query: 211 LVDNKY 194
+V+N +
Sbjct: 566 IVNNDF 571
[71][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 120 bits (300), Expect = 1e-25
Identities = 59/135 (43%), Positives = 84/135 (62%), Gaps = 1/135 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQK+YLE D + ++ + + P +T+ AV K + S+ NAVT
Sbjct: 447 WGPSNGYVYQKSYLELLVHPDVFNDMIGRIENHPDLTFYAVTKDGELRSNAPSDCPNAVT 506
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP KE++Q TIV++ SF WKDEAF + WA+ Y + PSR L++EV N +YLV+
Sbjct: 507 WGVFPGKEIVQPTIVESISFLAWKDEAFRL-GVDWAHCYDANSPSRALIDEVMNEWYLVN 565
Query: 211 LVDNKY-INGDIFSV 170
+V+N + N IF +
Sbjct: 566 IVNNDFHQNATIFEL 580
[72][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 119 bits (299), Expect = 1e-25
Identities = 58/136 (42%), Positives = 89/136 (65%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG G+VYQKAYLE F LD L+ + + P +TY AV K+ + ++T +S NA+T
Sbjct: 447 WGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLTYHAVAKNRELRTNTRDSP-NALT 505
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +E++Q TIVD SF WKDEA+ + WA + PSRKL++++ +++YLV+
Sbjct: 506 WGIFAGREIVQPTIVDTISFLAWKDEAYRL-GEDWAKCHDASSPSRKLIQDIMDNWYLVN 564
Query: 211 LVDNKYING-DIFSVF 167
+V+N + N D+F +F
Sbjct: 565 IVNNDFHNTYDLFDLF 580
[73][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6H337_AJECH
Length = 524
Score = 119 bits (299), Expect = 1e-25
Identities = 59/136 (43%), Positives = 89/136 (65%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLE S +D ++ + + P +TY VNK + ++T +S NAVT
Sbjct: 338 WGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKIGELRTNTTDSP-NAVT 396
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +KE+IQ TIV+ SF WKDEA+ + WA + PSR+++++V +S+YLV+
Sbjct: 397 WGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHVASSPSRRIIQQVMDSWYLVN 455
Query: 211 LVDNKY-INGDIFSVF 167
+V+N + DIF++F
Sbjct: 456 IVNNDFHKTHDIFNIF 471
[74][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 119 bits (299), Expect = 1e-25
Identities = 58/136 (42%), Positives = 89/136 (65%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG G+VYQKAYLE F LD L+ + + P +TY AV K+ + ++T +S NA+T
Sbjct: 447 WGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLTYHAVAKNRELRTNTRDSP-NALT 505
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +E++Q TIVD SF WKDEA+ + WA + PSRKL++++ +++YLV+
Sbjct: 506 WGIFAGREIVQPTIVDTISFLAWKDEAYRL-GEDWAKCHDASSPSRKLIQDIMDNWYLVN 564
Query: 211 LVDNKYING-DIFSVF 167
+V+N + N D+F +F
Sbjct: 565 IVNNDFHNTYDLFDLF 580
[75][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 119 bits (299), Expect = 1e-25
Identities = 61/136 (44%), Positives = 82/136 (60%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG P GYV+QK Y+EFF L+ L E K S++Y NK+ +++ NAVT
Sbjct: 450 WGPPNGYVFQKPYVEFFVHPSLLNELKETVKKLNSVSYFVTNKNGDLDTNSQYEIPNAVT 509
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP +E+IQ TIV++ SF WKDEA+ + WAN Y D SRKLL + ++L
Sbjct: 510 WGVFPNREIIQPTIVESTSFLAWKDEAYSL-GMEWANAYSPDSISRKLLVSMMKEWFLCV 568
Query: 211 LVDNKYING-DIFSVF 167
+VDN + NG +F VF
Sbjct: 569 IVDNDFQNGQSLFDVF 584
[76][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 119 bits (297), Expect = 2e-25
Identities = 61/137 (44%), Positives = 87/137 (63%), Gaps = 1/137 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLE + + + LV+K + IT+ AVNK+ + + NAVT
Sbjct: 447 WGPKNGYVYQKAYLELLVTPEVAEKLVKKLENQSEITFYAVNKTGN-LQTNAPGGPNAVT 505
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG++P KEVIQ TIV+ SF WK+EAF + S WA YP + SRK L+++ N++YLV+
Sbjct: 506 WGIYPGKEVIQPTIVEKISFLAWKEEAFRLGS-EWAKCYPAESESRKFLDDIFNNWYLVN 564
Query: 211 LVDNKYING-DIFSVFA 164
+V N + + IF +F+
Sbjct: 565 IVHNDFHDSTGIFDLFS 581
[77][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 118 bits (296), Expect = 3e-25
Identities = 59/136 (43%), Positives = 88/136 (64%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLE + + ++ + + P +TY A+NK+ + ++T +S NAVT
Sbjct: 447 WGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNPDLTYYAINKNGELKTNTSDSP-NAVT 505
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +KEVIQ TIV+ SF WKDEAF + WA + PSR+L++ V + +YLV+
Sbjct: 506 WGIFASKEVIQPTIVETVSFLAWKDEAFRL-GDDWAKCHDARSPSRQLIQRVMDEWYLVN 564
Query: 211 LVDNKY-INGDIFSVF 167
+V+N + DIF++F
Sbjct: 565 IVNNDFHKTHDIFNLF 580
[78][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 118 bits (296), Expect = 3e-25
Identities = 61/156 (39%), Positives = 94/156 (60%), Gaps = 21/156 (13%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEK--------SKAFPSITYMAVNKSEKWVSSTG 416
WG G+VYQK YLEFF L L+ S F ++T+ AVN + ++++
Sbjct: 445 WGPSNGFVYQKQYLEFFIPAKFLTKLISNIEELNKSYSSNFNTLTFYAVNAQGELITNSK 504
Query: 415 ESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPE----------D 266
E D+NAVTWG+FP KEV+Q TIV+ SF WKDEAF ++ ++W++L+ + D
Sbjct: 505 EDDINAVTWGIFPGKEVVQPTIVERCSFLAWKDEAFRVF-KAWSSLFKDQDQDEFEVLRD 563
Query: 265 DPSRKLLEEVKNSYYLVSLVDNKYI---NGDIFSVF 167
+R +L+++ + Y+LV++VDN Y+ N IF +F
Sbjct: 564 SKTRAVLDKLHDEYFLVNIVDNNYVQNPNVKIFDLF 599
[79][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 118 bits (296), Expect = 3e-25
Identities = 58/136 (42%), Positives = 89/136 (65%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLE S ++ ++ + + +TY VNK+ + ++T +S NAVT
Sbjct: 447 WGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVNKTGELRTNTSDSP-NAVT 505
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +KE+IQ TIV+ SF WKDEA+ + WA +P PSR+L+++V +++YLV+
Sbjct: 506 WGIFVSKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHPASSPSRRLIQQVMDTWYLVN 564
Query: 211 LVDNKY-INGDIFSVF 167
+V+N + DIF +F
Sbjct: 565 IVNNDFHRTHDIFDLF 580
[80][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 118 bits (296), Expect = 3e-25
Identities = 58/136 (42%), Positives = 89/136 (65%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLE S ++ ++ + + +TY VNK+ + ++T +S NAVT
Sbjct: 447 WGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVNKTGELRTNTSDSP-NAVT 505
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +KE+IQ TIV+ SF WKDEA+ + WA +P PSR+L+++V +++YLV+
Sbjct: 506 WGIFVSKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHPASSPSRRLIQQVMDTWYLVN 564
Query: 211 LVDNKY-INGDIFSVF 167
+V+N + DIF +F
Sbjct: 565 IVNNDFHRTHDIFDLF 580
[81][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 118 bits (296), Expect = 3e-25
Identities = 58/136 (42%), Positives = 89/136 (65%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLE S +D ++ + + P +TY VNK + ++T +S NAVT
Sbjct: 433 WGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKIGELRTNTTDSP-NAVT 491
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +KE+IQ TIV+ SF WKDEA+ + WA + PSR+++++V +++YLV+
Sbjct: 492 WGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHGASSPSRRIIQQVMDNWYLVN 550
Query: 211 LVDNKY-INGDIFSVF 167
+V+N + DIF++F
Sbjct: 551 IVNNDFHKTHDIFNIF 566
[82][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 118 bits (295), Expect = 4e-25
Identities = 55/127 (43%), Positives = 78/127 (61%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVS-STGESDVNAV 395
WGG GG VYQKAY E F S K + L + PS+ AVN + + + E V A+
Sbjct: 448 WGGKGGRVYQKAYFECFVSPSKANRLTQMVTDHPSLNMYAVNNAGQELRVGVEEGGVTAL 507
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWGVFP +E++Q TI D +F +W +EAF +W W NLY S L++E++++YYLV
Sbjct: 508 TWGVFPNREILQPTIFDPDTFLIWAEEAFSLWGSMWLNLYEYGSESYDLVQEIRDTYYLV 567
Query: 214 SLVDNKY 194
+L+DN +
Sbjct: 568 ALIDNDF 574
[83][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 118 bits (295), Expect = 4e-25
Identities = 59/136 (43%), Positives = 87/136 (63%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLE + + ++ + + P +TY A+NK+ + ++T +S NAVT
Sbjct: 447 WGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNPDLTYYAINKNGELKTNTSDSP-NAVT 505
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +KEVIQ TIV+ SF WKDEAF + WA + PSR+L++ V + +YLV+
Sbjct: 506 WGIFASKEVIQPTIVETVSFLAWKDEAFRL-GDDWAKCHDARSPSRQLIQRVMDEWYLVN 564
Query: 211 LVDNKY-INGDIFSVF 167
+V+N + DIF +F
Sbjct: 565 IVNNDFHKTHDIFDLF 580
[84][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 118 bits (295), Expect = 4e-25
Identities = 57/136 (41%), Positives = 89/136 (65%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG G+VYQKAYLE F LD L+ + + P +TY AV K+ + ++T +S NA+T
Sbjct: 447 WGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLTYHAVAKNRELRTNTRDSP-NALT 505
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +E++Q TIV+ SF WKDEA+ + WA + PSRKL++++ +++YLV+
Sbjct: 506 WGIFAGREIVQPTIVETISFLAWKDEAYRL-GEDWAKCHDASSPSRKLIQDIMDNWYLVN 564
Query: 211 LVDNKYING-DIFSVF 167
+V+N + N D+F +F
Sbjct: 565 IVNNDFHNTYDLFDLF 580
[85][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 117 bits (294), Expect = 5e-25
Identities = 58/136 (42%), Positives = 89/136 (65%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLE S ++ ++ + + +TY VNK+ + ++T +S NAVT
Sbjct: 447 WGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVNKTGELRTNTTDSP-NAVT 505
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +KE+IQ TIV+ SF WKDEA+ + WA +P PSR+L+++V +++YLV+
Sbjct: 506 WGIFVSKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHPASSPSRRLIQQVMDTWYLVN 564
Query: 211 LVDNKY-INGDIFSVF 167
+V+N + DIF +F
Sbjct: 565 IVNNDFHRTHDIFDLF 580
[86][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
RepID=A8PV87_BRUMA
Length = 656
Score = 117 bits (293), Expect = 6e-25
Identities = 60/128 (46%), Positives = 78/128 (60%), Gaps = 2/128 (1%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEK--WVSSTGESDVNA 398
WG PGGY YQKAYLEFF S+ + L ++ + VN W ++ + A
Sbjct: 515 WGKPGGYCYQKAYLEFFTSQANAEVLWSLLPSYSRLNCHIVNHDATIDWTNTETTMPI-A 573
Query: 397 VTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYL 218
VTWGVFP E+ Q T+VD SF+VWKDEAF W +W+++Y E SR LLE++ N Y L
Sbjct: 574 VTWGVFPGSEIAQPTVVDPLSFRVWKDEAFSAW-LNWSSIYAEGTSSRCLLEKIYNEYCL 632
Query: 217 VSLVDNKY 194
V+LVDN Y
Sbjct: 633 VTLVDNDY 640
[87][TOP]
>UniRef100_B6JY06 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6JY06_SCHJY
Length = 626
Score = 117 bits (293), Expect = 6e-25
Identities = 52/128 (40%), Positives = 82/128 (64%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GG+V+QKA++E F S + L ++ P ITY+A N ++ ++ NAVT
Sbjct: 490 WGPRGGWVFQKAFVEMFMSTMDFEALAQRLHDNPQITYLAGNNKGEFKTNASLDSANAVT 549
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP +E+IQ+TI+ SF+ W+DEA+ IW WA LYP PS KL++ ++ +LVS
Sbjct: 550 WGVFPGREIIQSTIIAPVSFQAWRDEAYSIWG-EWARLYPAGTPSHKLIQSCIDNCWLVS 608
Query: 211 LVDNKYIN 188
++ + +++
Sbjct: 609 VIHHNFLD 616
[88][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 116 bits (291), Expect = 1e-24
Identities = 53/129 (41%), Positives = 88/129 (68%), Gaps = 3/129 (2%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCS---KDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVN 401
+G PGG+V+QK+++E F S KD+L ++ A ITY A N + S+ G+ + N
Sbjct: 545 FGPPGGFVFQKSFVELFVSSSDKDRLVARIDALGASAPITYFAGNAKGDFQSNLGDEEAN 604
Query: 400 AVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYY 221
VTW VFP KE++Q+TI++ SF+ W++EAFEIW+ W+ L+P+ SR+L++E++ + +
Sbjct: 605 TVTWAVFPGKEIVQSTIIERQSFEAWREEAFEIWA-EWSLLFPKKSASRQLIDEIREARW 663
Query: 220 LVSLVDNKY 194
LV++V + Y
Sbjct: 664 LVTVVHHDY 672
[89][TOP]
>UniRef100_Q8MQE7 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis elegans
RepID=Q8MQE7_CAEEL
Length = 642
Score = 115 bits (288), Expect = 2e-24
Identities = 54/129 (41%), Positives = 80/129 (62%), Gaps = 3/129 (2%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEK-SKAFP-SITYMAVNKSEKWVSSTGESDVN- 401
WG PGGY YQKAYLE F + + D L++ + FP + Y A+NK + + E
Sbjct: 495 WGKPGGYCYQKAYLECFMTAELSDKLIQIIEREFPVRVNYHAINKDSTFDKTNSEETTPI 554
Query: 400 AVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYY 221
AVTWGVFP E+ Q T+VD SF+ W+DEA+++W W + YP++ S +++ V + +
Sbjct: 555 AVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQWGDFYPKESKSYGVIKAVHDEFR 614
Query: 220 LVSLVDNKY 194
LV+LVDN +
Sbjct: 615 LVTLVDNDF 623
[90][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 115 bits (288), Expect = 2e-24
Identities = 59/152 (38%), Positives = 89/152 (58%), Gaps = 1/152 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLE S + + ++ + + P TY AVNK ++ NAVT
Sbjct: 447 WGPRNGYVYQKAYLEVLVSPEYIAEIITRIERDPEFTYYAVNKDGDLKTNAPNEGPNAVT 506
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP KE++Q TIV+ SF WKDE + + + WAN + PSR ++++V +++YL++
Sbjct: 507 WGVFPGKEIVQPTIVETVSFLAWKDEFYRL-GQQWANCHGGASPSRFVIQDVVDTWYLLN 565
Query: 211 LVDNKY-INGDIFSVFA*CPRKAPAKRKHSIS 119
+V N + IF +F K K+ HS++
Sbjct: 566 IVHNDFHATRGIFPIFDGLQVKDIDKKLHSVN 597
[91][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 115 bits (288), Expect = 2e-24
Identities = 55/126 (43%), Positives = 77/126 (61%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG P GYVYQKAYLE + L E+ P +TY AV KS ++ NAVT
Sbjct: 442 WGPPNGYVYQKAYLELLVHPAIFEQLKERIHDHPDLTYYAVTKSGNLHTNATYEGPNAVT 501
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP KE++Q T+V+ SF WKDEAF++ WA + ++ PSR L++ + +YLV+
Sbjct: 502 WGVFPGKEIVQPTVVENISFLAWKDEAFQL-GMEWARCHDQNTPSRILIQSMMQEWYLVN 560
Query: 211 LVDNKY 194
+V+N +
Sbjct: 561 IVNNDF 566
[92][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 115 bits (288), Expect = 2e-24
Identities = 59/136 (43%), Positives = 87/136 (63%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG G+VYQKAYLE F LD L+ + + +TY AV K + ++T +S NA+T
Sbjct: 447 WGPKNGFVYQKAYLELFVPPYLLDELIARIEKNDDLTYHAVAKEGELRTNTRDSP-NALT 505
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +E++Q TIV+ SF WKDEA+ + WA + PSRKL++EV +S+YLV+
Sbjct: 506 WGIFAGREIVQPTIVETISFLAWKDEAYRL-GEDWAKCHEAASPSRKLIQEVVDSWYLVN 564
Query: 211 LVDNKYING-DIFSVF 167
+V+N + N D+F +F
Sbjct: 565 IVNNDFHNTYDLFELF 580
[93][TOP]
>UniRef100_Q17693 Probable methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis
elegans RepID=MTHR_CAEEL
Length = 663
Score = 115 bits (288), Expect = 2e-24
Identities = 54/129 (41%), Positives = 80/129 (62%), Gaps = 3/129 (2%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEK-SKAFP-SITYMAVNKSEKWVSSTGESDVN- 401
WG PGGY YQKAYLE F + + D L++ + FP + Y A+NK + + E
Sbjct: 516 WGKPGGYCYQKAYLECFMTAELSDKLIQIIEREFPVRVNYHAINKDSTFDKTNSEETTPI 575
Query: 400 AVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYY 221
AVTWGVFP E+ Q T+VD SF+ W+DEA+++W W + YP++ S +++ V + +
Sbjct: 576 AVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQWGDFYPKESKSYGVIKAVHDEFR 635
Query: 220 LVSLVDNKY 194
LV+LVDN +
Sbjct: 636 LVTLVDNDF 644
[94][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 115 bits (287), Expect = 3e-24
Identities = 50/113 (44%), Positives = 73/113 (64%), Gaps = 1/113 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYVYQKAYLEFF S + + L++ K + P + Y VN + +++ + NAV
Sbjct: 504 WGPAGGYVYQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPNAV 563
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
TWG+F +E++Q T+VD SF WKDEAF +W WA LY ++ PSR +++ +
Sbjct: 564 TWGIFAGREIVQPTVVDPVSFMSWKDEAFALWIEQWAKLYEDESPSRMIIQYI 616
[95][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 114 bits (286), Expect = 4e-24
Identities = 58/136 (42%), Positives = 87/136 (63%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLE S +D ++ + + +TY VNK + ++T +S NAVT
Sbjct: 447 WGPKNGYVYQKAYLELLISPTMIDDVISRIEQNSDLTYYCVNKKGELKTNTTDSP-NAVT 505
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +KE+IQ TIV+ SF WKDEA+ + WA + SR+L+E+V +++YLV+
Sbjct: 506 WGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHAPSSLSRRLIEQVMDTWYLVN 564
Query: 211 LVDNKY-INGDIFSVF 167
+V+N + DIF++F
Sbjct: 565 IVNNDFHKTHDIFNLF 580
[96][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 114 bits (286), Expect = 4e-24
Identities = 58/136 (42%), Positives = 87/136 (63%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLE S +D ++ + + +TY VNK + ++T +S NAVT
Sbjct: 447 WGPKNGYVYQKAYLELLISPTMIDDVISRIEQNSDLTYYCVNKKGELKTNTTDSP-NAVT 505
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +KE+IQ TIV+ SF WKDEA+ + WA + SR+L+E+V +++YLV+
Sbjct: 506 WGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHAPSSLSRRLIEQVMDTWYLVN 564
Query: 211 LVDNKY-INGDIFSVF 167
+V+N + DIF++F
Sbjct: 565 IVNNDFHKTHDIFNLF 580
[97][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 114 bits (286), Expect = 4e-24
Identities = 58/136 (42%), Positives = 86/136 (63%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLE + +D ++ + + +TY A NK+ + ++T +S NAVT
Sbjct: 447 WGPKNGYVYQKAYLELLIPPEIIDEVITRIQKNADLTYYATNKNGELKTNTSDSP-NAVT 505
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +KEVIQ TIV+ SF WKDEA+ + WA + PSR+L++ V + +YLV+
Sbjct: 506 WGIFASKEVIQPTIVETVSFLAWKDEAYRL-GDDWAKCHDARSPSRQLIQRVMDEWYLVN 564
Query: 211 LVDNKY-INGDIFSVF 167
+V+N + DIF +F
Sbjct: 565 IVNNDFHKTHDIFDLF 580
[98][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 114 bits (286), Expect = 4e-24
Identities = 52/126 (41%), Positives = 79/126 (62%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLE F S + + ++ + + P TY AVNK ++ NAVT
Sbjct: 447 WGPRNGYVYQKAYLEVFVSPEYISEIITRLERDPEFTYYAVNKDGDLKTNAPNEGPNAVT 506
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP KE++Q TIV+ SF WKDE + + + WAN + PSR +++++ +++YL++
Sbjct: 507 WGVFPGKEIVQPTIVETVSFLAWKDEFYRL-GQQWANCHAGVSPSRYVIQDIVDTWYLLN 565
Query: 211 LVDNKY 194
+V N +
Sbjct: 566 IVHNDF 571
[99][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 114 bits (285), Expect = 5e-24
Identities = 57/136 (41%), Positives = 87/136 (63%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG G+VYQKAYLE +D L+ + +A +TY AV K + ++T +S NA+T
Sbjct: 447 WGPKNGFVYQKAYLELLVPPYVIDELIARIEANEDLTYHAVTKKGELRTNTRDSP-NALT 505
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +EV+Q TIV+ SF WKDEA+++ WA + P+RKLL+ + +S+YLV+
Sbjct: 506 WGIFAGREVVQPTIVETVSFLAWKDEAYQL-GEDWAKCHEASSPTRKLLQGIMDSWYLVN 564
Query: 211 LVDNKYING-DIFSVF 167
+V+N + N D+F +F
Sbjct: 565 IVNNDFHNTYDLFELF 580
[100][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 114 bits (285), Expect = 5e-24
Identities = 55/136 (40%), Positives = 86/136 (63%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLE S +D ++ + + P +TY +NK+ + +++ ++ NAVT
Sbjct: 447 WGPKNGYVYQKAYLELLISPTLIDEVIRRIETNPDLTYHCINKNGELRTNSSDTP-NAVT 505
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +KEVIQ TIV+ SF WKDEA+ + WA + PSRK+++ +++YL +
Sbjct: 506 WGIFASKEVIQPTIVETVSFLAWKDEAYRL-GDDWAKCHDASSPSRKIIQNTMDTWYLFN 564
Query: 211 LVDNKY-INGDIFSVF 167
+V+N + DIF +F
Sbjct: 565 IVNNDFHKTHDIFDLF 580
[101][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NEV2_COPC7
Length = 617
Score = 114 bits (285), Expect = 5e-24
Identities = 56/137 (40%), Positives = 85/137 (62%), Gaps = 2/137 (1%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS--ITYMAVNKSEKWVSSTGESDVNA 398
WG GYV+QK ++EFFC ++ + ++ K + + Y N + + S+ E NA
Sbjct: 473 WGPRAGYVFQKGFVEFFCDFHDVEAIEQRIKQRGAGWVHYFMANNNGECRSNVPEDGRNA 532
Query: 397 VTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYL 218
VTWGVFP +E+ Q TI++ SF WKDEA++IW+ SWA+LY D R+LL++V N +L
Sbjct: 533 VTWGVFPGQEIQQTTIIEKESFLTWKDEAYDIWN-SWASLYHPDSAERQLLQKVANERWL 591
Query: 217 VSLVDNKYINGDIFSVF 167
VS+V ++Y N + F
Sbjct: 592 VSIVHHEYKNPNALWTF 608
[102][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 114 bits (284), Expect = 7e-24
Identities = 55/121 (45%), Positives = 75/121 (61%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLE + D + LV + + P +TY AV K+ ++ NAVT
Sbjct: 447 WGPTNGYVYQKAYLELLVAPDMMPELVRRIQHDPDLTYYAVKKTGDLQTNAQSDGPNAVT 506
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP KE++Q TIV+ SF WKDEAF + WA+ + PSR L+E + +S+YLV+
Sbjct: 507 WGVFPGKEIVQPTIVETISFLAWKDEAFRL-GTDWAHCHSALSPSRGLIESIMDSWYLVN 565
Query: 211 L 209
+
Sbjct: 566 I 566
[103][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR2_SCHPO
Length = 641
Score = 114 bits (284), Expect = 7e-24
Identities = 51/128 (39%), Positives = 82/128 (64%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GG V+QKA++E F + L + K P +TY A N +++++ + +AVT
Sbjct: 503 WGPKGGRVFQKAFVECFVNGKDLKDFITKWHDNPQVTYYAGNNKSEFLTNAPKDGASAVT 562
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGV+P +E+IQ+TI+ SFK W E+F++W WANLY ++ PSRKLLE N +LV+
Sbjct: 563 WGVYPGREIIQSTIIAEVSFKAWLSESFQVWG-EWANLYSKNTPSRKLLENCINDRWLVT 621
Query: 211 LVDNKYIN 188
++ + +++
Sbjct: 622 VIHHDFMD 629
[104][TOP]
>UniRef100_Q6FNS2 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FNS2_CANGA
Length = 645
Score = 112 bits (280), Expect = 2e-23
Identities = 55/133 (41%), Positives = 79/133 (59%), Gaps = 3/133 (2%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF---PSITYMAVNKSEKWVSSTGESDVN 401
WG G+VYQKA++E F + + T+++ + +Y A + + ++ N
Sbjct: 506 WGPSKGHVYQKAFIEMFVHRQQWKTILKPKLDYYGRRKFSYYAGDSKGSFETNLDPHSSN 565
Query: 400 AVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYY 221
VTWGVFP +VIQ TI++ SFK W+DEAF IWS WA L+P + PS LL EV + YY
Sbjct: 566 VVTWGVFPNSQVIQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPSNTLLREVHSDYY 624
Query: 220 LVSLVDNKYINGD 182
LVS+V + +I D
Sbjct: 625 LVSIVHHDFIETD 637
[105][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 112 bits (280), Expect = 2e-23
Identities = 56/136 (41%), Positives = 88/136 (64%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG G+VYQKAYLE LD L+ + + +TY AV+K+ + ++T +S NA+T
Sbjct: 447 WGPKNGFVYQKAYLELLVPPYLLDELIARIEKNEDLTYHAVSKTGELRTNTRDSP-NALT 505
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +EV+Q TIV+ SF WKDEA+ + WA + PSRKL+++V +++YLV+
Sbjct: 506 WGIFAGREVVQPTIVETISFLAWKDEAYRL-GEDWAKCHEAGSPSRKLIQDVMDNWYLVN 564
Query: 211 LVDNKYING-DIFSVF 167
+V+N + N ++F +F
Sbjct: 565 IVNNDFHNSFNLFELF 580
[106][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 112 bits (279), Expect = 3e-23
Identities = 57/136 (41%), Positives = 87/136 (63%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG G+VYQKAYLE LD L+ + + +TY AV+K+ + ++T +S NA+T
Sbjct: 447 WGPKNGFVYQKAYLELLIPPYLLDELIARIEGNEDLTYHAVSKNGELRTNTHDSP-NALT 505
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +EV+Q TIV+ SF WKDEA+ + WA + PSRKL++ + +S+YLV+
Sbjct: 506 WGIFAGREVVQPTIVETISFLAWKDEAYRL-GEDWAKCHAATSPSRKLIQGLVDSWYLVN 564
Query: 211 LVDNKYING-DIFSVF 167
+V+N + N D+F +F
Sbjct: 565 IVNNDFHNTYDLFELF 580
[107][TOP]
>UniRef100_UPI0000123E6B Hypothetical protein CBG12960 n=1 Tax=Caenorhabditis briggsae AF16
RepID=UPI0000123E6B
Length = 662
Score = 111 bits (278), Expect = 3e-23
Identities = 50/129 (38%), Positives = 81/129 (62%), Gaps = 3/129 (2%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEK-SKAFP-SITYMAVNKSEKWVSSTGESDVN- 401
WG PGGY YQKAYLE F + + + L++ + +P + Y A++K + + E
Sbjct: 517 WGKPGGYCYQKAYLECFMTAELSEKLIDIIEREYPVRVNYHAIDKDSSFDKTNSEETTPI 576
Query: 400 AVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYY 221
AVTWGVFP E+ Q T+VD SF+ W+DEA+++W W + YP++ S +++ + +++
Sbjct: 577 AVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQWGDFYPKESKSYGVIKSIHDTFR 636
Query: 220 LVSLVDNKY 194
LV+LVDN +
Sbjct: 637 LVTLVDNDF 645
[108][TOP]
>UniRef100_C5DIA7 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5DIA7_LACTC
Length = 660
Score = 110 bits (275), Expect = 8e-23
Identities = 55/133 (41%), Positives = 82/133 (61%), Gaps = 3/133 (2%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP---SITYMAVNKSEKWVSSTGESDVN 401
WG PGGYVYQK+++E F K + + + K K P ++Y + +E + ++ S +
Sbjct: 522 WGPPGGYVYQKSFVEMFVHKQQWELEI-KPKLEPLGSKVSYYVGDSAETFYTNLDSSCSS 580
Query: 400 AVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYY 221
VTWGVFP EV+Q TIV+ SFK W+DEAF IW W+ L+P + S LL+++ YY
Sbjct: 581 VVTWGVFPNSEVLQTTIVEEESFKAWRDEAFSIW-LEWSKLFPRNSRSNTLLKQMHRDYY 639
Query: 220 LVSLVDNKYINGD 182
LVS+V + + + D
Sbjct: 640 LVSIVHHDFSDCD 652
[109][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 109 bits (273), Expect = 1e-22
Identities = 58/131 (44%), Positives = 81/131 (61%), Gaps = 3/131 (2%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSS-TGESDVNAV 395
WG GYVYQK YLEF K KL L + PS+TY AV+ +++ S+ ++ NAV
Sbjct: 457 WGPNNGYVYQKQYLEFLLPKSKLSQLRDFVNDMPSLTYFAVDSADELHSNHPDDTAANAV 516
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRK--LLEEVKNSYY 221
TWG+FP +EV+Q TIV+ SF WK+E F+I W + E++ S LLE V + Y
Sbjct: 517 TWGIFPGREVLQPTIVEKVSFLAWKEEFFDILD-EWKRIMGENNHSESVALLESVISDYL 575
Query: 220 LVSLVDNKYIN 188
LV++VDN Y++
Sbjct: 576 LVNIVDNDYVS 586
[110][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 109 bits (272), Expect = 2e-22
Identities = 57/130 (43%), Positives = 77/130 (59%), Gaps = 4/130 (3%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSK--AFPSITYMAVNKSE--KWVSSTGESDV 404
WG GGYV+QK ++EFFC + +D + + + + Y A N + S+ E
Sbjct: 458 WGPRGGYVFQKGFVEFFCEEKDMDVIERRVERNGHGWVHYFAGNYKADGECRSNVPEGGR 517
Query: 403 NAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSY 224
NAVTWGVFP +E+ Q TI++ SF WKDEAF IWS WA+ Y RKLLE V+N
Sbjct: 518 NAVTWGVFPGQEIAQTTIIEKESFLTWKDEAFSIWS-EWASFYRPGSEERKLLEGVRNER 576
Query: 223 YLVSLVDNKY 194
+LVS+V + Y
Sbjct: 577 WLVSIVHHDY 586
[111][TOP]
>UniRef100_A8XGR9 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis briggsae
RepID=A8XGR9_CAEBR
Length = 724
Score = 108 bits (271), Expect = 2e-22
Identities = 50/139 (35%), Positives = 85/139 (61%), Gaps = 13/139 (9%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEK-SKAFP-SITYMAVNKSEKWV---------- 428
WG PGGY YQKAYLE F + + + L++ + +P + Y A++K ++
Sbjct: 567 WGKPGGYCYQKAYLECFMTAELSEKLIDIIEREYPVRVNYHAIDKDVSYILNSHDSMQIF 626
Query: 427 -SSTGESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRK 251
+++ E+ AVTWGVFP E+ Q T+VD SF+ W+DEA+++W W + YP++ S
Sbjct: 627 RTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQWGDFYPKESKSYG 686
Query: 250 LLEEVKNSYYLVSLVDNKY 194
+++ + +++ LV+LVDN +
Sbjct: 687 VIKSIHDTFRLVTLVDNDF 705
[112][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 108 bits (271), Expect = 2e-22
Identities = 54/136 (39%), Positives = 87/136 (63%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQKAYLE +D L+ + + +TY AV+K+ + ++T +S NA+T
Sbjct: 447 WGPKNGYVYQKAYLELLVPPYLIDELIARIEKNGDLTYHAVSKTGELRTNTRDSP-NALT 505
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +E++Q TIV+ SF WKDEA+ + WA + PSRKL++ V ++++LV+
Sbjct: 506 WGIFAGREIVQPTIVETVSFLAWKDEAYRL-GDDWAKCHDTSSPSRKLIQGVMDNWHLVN 564
Query: 211 LVDNKYIN-GDIFSVF 167
+V+N + N ++F +F
Sbjct: 565 IVNNDFHNTSNLFDLF 580
[113][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 108 bits (270), Expect = 3e-22
Identities = 53/136 (38%), Positives = 83/136 (61%), Gaps = 1/136 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG G+VYQKAYLE + +D L+ + + +TY A NK + ++T +S NA+T
Sbjct: 447 WGPKNGFVYQKAYLELLVPSNLIDELITRIEKNDDLTYHATNKKGELKTNTRDSP-NALT 505
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG+F +E+IQ TIV+ SF WKDEA+ + W+ + PSR+L++ V +YLV+
Sbjct: 506 WGIFAGREIIQPTIVETVSFLAWKDEAY-LLGEHWSKCHDAASPSRQLIQHVMEDWYLVN 564
Query: 211 LVDNKYINGD-IFSVF 167
+VDN + + +F +F
Sbjct: 565 IVDNDFHRSNAVFELF 580
[114][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 107 bits (268), Expect = 5e-22
Identities = 54/146 (36%), Positives = 85/146 (58%), Gaps = 16/146 (10%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS---------ITYMAVNKSEKWVSST 419
WG GYVYQK YLEFFC KD + L++ + I+Y AVNK+ +S+
Sbjct: 452 WGPKNGYVYQKQYLEFFCHKDVVARLLDHIDQYNKNQGDSTSAVISYYAVNKNGNLISNC 511
Query: 418 GESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSR----- 254
+ D+NAVTWGVFP +E++Q TIV+ SF WKDE + ++S W+ + D +
Sbjct: 512 QDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYTLFS-EWSKISGMFDAEKDKIQH 570
Query: 253 --KLLEEVKNSYYLVSLVDNKYINGD 182
+L+ ++ ++ L +LV+N ++ G+
Sbjct: 571 FNELMSQITENFVLCNLVNNDFLQGN 596
[115][TOP]
>UniRef100_Q6CEM7 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CEM7_YARLI
Length = 625
Score = 107 bits (267), Expect = 6e-22
Identities = 54/131 (41%), Positives = 79/131 (60%), Gaps = 1/131 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWV-SSTGESDVNAV 395
WG GGYV+QK++ EFF S ++ L A + V KS+K V ++ E N V
Sbjct: 487 WGPKGGYVFQKSFAEFFISPEQWKKLKPLLDAQEDLVSYYVAKSDKLVDTNVSERASNGV 546
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWGVFP +E++Q TI+ SF W++EAF IWS W LY ++ S KLL+++ N Y LV
Sbjct: 547 TWGVFPNREIVQTTIIQEDSFDAWREEAFSIWS-EWRALYKKNTASFKLLDKIINEYLLV 605
Query: 214 SLVDNKYINGD 182
+++ + Y+ D
Sbjct: 606 TVIHHDYVEED 616
[116][TOP]
>UniRef100_C4Y9Q4 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y9Q4_CLAL4
Length = 601
Score = 106 bits (264), Expect = 1e-21
Identities = 53/132 (40%), Positives = 80/132 (60%), Gaps = 5/132 (3%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSK---DKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGE--SD 407
WG G ++QK+++EFF K ++L L++K + +ITY N + ++ S
Sbjct: 460 WGPRNGRIFQKSFVEFFVPKTEWERLLRLMDKDISDKTITYFCGNSKGEITTNMPHKSSQ 519
Query: 406 VNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNS 227
A+TWGVFP+KEV+Q T++D SF+ W +EAF +W WA Y D PS +LL + +
Sbjct: 520 RTAITWGVFPSKEVLQPTVIDRQSFQAWNEEAFGLW-LDWARCYAPDSPSYRLLAGIHSD 578
Query: 226 YYLVSLVDNKYI 191
YYLVS+V N Y+
Sbjct: 579 YYLVSIVHNNYL 590
[117][TOP]
>UniRef100_UPI000151BABB hypothetical protein PGUG_04648 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151BABB
Length = 355
Score = 105 bits (263), Expect = 2e-21
Identities = 57/157 (36%), Positives = 89/157 (56%), Gaps = 22/157 (14%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS--------ITYMAVNKSEKWVSSTG 416
WG GYV+QK YLEFFC +D L+E + F +TY A +K+ + ++T
Sbjct: 192 WGPKNGYVFQKQYLEFFCHRDIFPKLLESIEKFNEKGGESCSFLTYYAADKNGELNTNTK 251
Query: 415 ESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLY----PEDDPSRK- 251
E D+NAVTWGVFP +E++Q TIV+ SF WKDE + + + W ++Y D+ +K
Sbjct: 252 EDDINAVTWGVFPGEEILQPTIVEKTSFFAWKDEVYRLLA-EWGSVYDSHITSDETLKKS 310
Query: 250 -------LLEEVKNSYYLVSLVDNKYINGD--IFSVF 167
L E + + L ++V+N +++ D +FS+F
Sbjct: 311 QVKEFTHTLNEFADQFILCNIVNNNFVDDDLVLFSIF 347
[118][TOP]
>UniRef100_C7YTQ6 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YTQ6_NECH7
Length = 674
Score = 105 bits (263), Expect = 2e-21
Identities = 56/143 (39%), Positives = 80/143 (55%), Gaps = 13/143 (9%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEK---SKAFPSITYMAVNKSEKWVSSTGESDV- 404
WG P G+V+QK+++EFF + L EK S+ S+ + A N +VSS V
Sbjct: 525 WGPPNGFVFQKSFVEFFIPSSEWSVLKEKLNSSELCDSVCFYAGNAKGDFVSSDKGGHVD 584
Query: 403 ---------NAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRK 251
NAVTWGVFP KE+I TI++ SF+ W +EAF IW WA +Y S K
Sbjct: 585 GSSGAGPSTNAVTWGVFPGKEIITPTIIEEVSFRAWCEEAFGIWG-EWAKVYGRGSDSEK 643
Query: 250 LLEEVKNSYYLVSLVDNKYINGD 182
LL +K+ Y+LV+L+ + ++ D
Sbjct: 644 LLSGIKDEYWLVNLIHHDFVEKD 666
[119][TOP]
>UniRef100_A5DMZ7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DMZ7_PICGU
Length = 355
Score = 105 bits (263), Expect = 2e-21
Identities = 57/157 (36%), Positives = 89/157 (56%), Gaps = 22/157 (14%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS--------ITYMAVNKSEKWVSSTG 416
WG GYV+QK YLEFFC +D L+E + F +TY A +K+ + ++T
Sbjct: 192 WGPKNGYVFQKQYLEFFCHRDIFPKLLESIEKFNEKGGESCSFLTYYAADKNGELNTNTK 251
Query: 415 ESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLY----PEDDPSRK- 251
E D+NAVTWGVFP +E++Q TIV+ SF WKDE + + + W ++Y D+ +K
Sbjct: 252 EDDINAVTWGVFPGEEILQPTIVEKTSFFAWKDEVYRLLA-EWGSVYDSHITSDETLKKS 310
Query: 250 -------LLEEVKNSYYLVSLVDNKYINGD--IFSVF 167
L E + + L ++V+N +++ D +FS+F
Sbjct: 311 QVKEFTHTLNEFADQFILCNIVNNNFVDDDSVLFSIF 347
[120][TOP]
>UniRef100_UPI000023F2EE hypothetical protein FG07127.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023F2EE
Length = 672
Score = 105 bits (262), Expect = 2e-21
Identities = 55/143 (38%), Positives = 80/143 (55%), Gaps = 13/143 (9%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEK---SKAFPSITYMAVNKSEKWVSST------ 419
WG P G+V+QK+++EFF ++ + L K S+ + + A N +VSS
Sbjct: 523 WGPPNGFVFQKSFVEFFIPANEWEILKAKLVSSELQDYVCFYASNARGDYVSSDIGGHVD 582
Query: 418 ----GESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRK 251
NAVTWGVFP KE+I TI++ SF+ W +EAF IW WA +Y S K
Sbjct: 583 GSTEASPSTNAVTWGVFPGKEIITPTIIEEVSFRAWCEEAFGIWG-EWAKVYGRGSESEK 641
Query: 250 LLEEVKNSYYLVSLVDNKYINGD 182
LL +K+ Y+LV+L+ + Y+N D
Sbjct: 642 LLNGIKDDYWLVNLIHHDYVNRD 664
[121][TOP]
>UniRef100_Q0UB79 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UB79_PHANO
Length = 543
Score = 105 bits (262), Expect = 2e-21
Identities = 51/130 (39%), Positives = 76/130 (58%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYV+QK ++EFF + L + A +TY A N + + +S+ ES VN VT
Sbjct: 408 WGPKNGYVFQKPFVEFFLPAAEFHALRTRLDAHDQVTYFAGNANGDFEASSEES-VNPVT 466
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG F KE++ TI++A SF+ W +EAF IW R W +YP S KLL + + +LV+
Sbjct: 467 WGTFAGKEIVTPTIIEAVSFRSWLEEAFSIW-REWQRIYPTKSASGKLLGQTREDVWLVN 525
Query: 211 LVDNKYINGD 182
++ ++ GD
Sbjct: 526 VIWGDFVQGD 535
[122][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 104 bits (259), Expect = 5e-21
Identities = 53/147 (36%), Positives = 88/147 (59%), Gaps = 17/147 (11%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF---------PSITYMAVNKSEKWVSST 419
WG GYVYQK YLEFFC KD + L+++ + F I+Y AV+K ++
Sbjct: 452 WGPKNGYVYQKQYLEFFCHKDVVSKLLDQVEEFNIKGAESSSAFISYYAVDKDGNLSTNC 511
Query: 418 GESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEI---WSRSWANLYPEDDPSR-- 254
+ D+NAVTWGVFP +E++Q TIV+ SF WKDE + + W++ ++ E D ++
Sbjct: 512 KDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFTEWAKIASSNLVEADQTQVN 571
Query: 253 ---KLLEEVKNSYYLVSLVDNKYINGD 182
+L+++ + + L +LV+N +++G+
Sbjct: 572 EFVRLMKKFGDEFVLCNLVNNDFVDGN 598
[123][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 103 bits (258), Expect = 7e-21
Identities = 56/150 (37%), Positives = 86/150 (57%), Gaps = 20/150 (13%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLV-----------EKSKAFPSITYMAVNKSEKWVS 425
WG GYVYQK YLEFFC KD + L+ E S AF I+Y AV+K +
Sbjct: 452 WGPKNGYVYQKQYLEFFCHKDVVSKLLDHVEEFNVKGAESSSAF--ISYYAVDKDGNLST 509
Query: 424 STGESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPED------- 266
+ + D+NAVTWGVFP +E++Q TIV+ SF WKDE + +++ WA + +
Sbjct: 510 NCKDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFT-EWAKIASSNLVEANQT 568
Query: 265 --DPSRKLLEEVKNSYYLVSLVDNKYINGD 182
D +L+++ + + L +LV+N +++G+
Sbjct: 569 QVDEFVQLMKKFGDEFVLCNLVNNDFVDGN 598
[124][TOP]
>UniRef100_A7TRT4 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TRT4_VANPO
Length = 645
Score = 103 bits (257), Expect = 9e-21
Identities = 55/133 (41%), Positives = 79/133 (59%), Gaps = 3/133 (2%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVE-KSKAFP--SITYMAVNKSEKWVSSTGESDVN 401
WG GYVYQKA++E F K + + +V+ K +P +Y + S + S+ + N
Sbjct: 506 WGPKNGYVYQKAFVEMFILKKQWEAIVKPKLDHYPRGKFSYYVGDSSGSFESNLETNSSN 565
Query: 400 AVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYY 221
VTWGVFP VIQ TIV+ SFK W+DEAF IW WA L+P ++ S L++V ++Y
Sbjct: 566 VVTWGVFPNSPVIQTTIVEEESFKAWRDEAFCIW-LEWAKLFPSNELSNSFLKQVHSTYC 624
Query: 220 LVSLVDNKYINGD 182
LVS+V + + D
Sbjct: 625 LVSIVHHDFSETD 637
[125][TOP]
>UniRef100_Q6CR34 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CR34_KLULA
Length = 649
Score = 103 bits (256), Expect = 1e-20
Identities = 50/132 (37%), Positives = 78/132 (59%), Gaps = 2/132 (1%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS--ITYMAVNKSEKWVSSTGESDVNA 398
WG G +YQKA++E F K++ + +++ + +Y + + + ++ NA
Sbjct: 511 WGPANGLIYQKAFVEIFVRKEEWNQVLKPKIESKNGEFSYYLGDYTGYFETNLQPKSSNA 570
Query: 397 VTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYL 218
VTWGVFP EV+Q TIV+ SFK W+DEAF IW W+ L+P++ P L ++ YYL
Sbjct: 571 VTWGVFPNSEVVQTTIVEEESFKAWRDEAFSIWI-EWSKLFPKNTPENTFLRKMHRDYYL 629
Query: 217 VSLVDNKYINGD 182
VS+V + +IN D
Sbjct: 630 VSIVHHDFINPD 641
[126][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 103 bits (256), Expect = 1e-20
Identities = 54/132 (40%), Positives = 79/132 (59%), Gaps = 2/132 (1%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGE-SDVNAV 395
WG GYVYQK YLEF K KL L++ K +TY A++ +S+ + S NAV
Sbjct: 459 WGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAV 518
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDP-SRKLLEEVKNSYYL 218
TWG+FP +E++Q TIV+ SF WK+E + I + N+ D P S + ++ + + Y L
Sbjct: 519 TWGIFPGREILQPTIVEKISFLAWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYCL 578
Query: 217 VSLVDNKYINGD 182
V++VDN YI+ D
Sbjct: 579 VNIVDNDYISPD 590
[127][TOP]
>UniRef100_B5VIK4 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VIK4_YEAS6
Length = 411
Score = 103 bits (256), Expect = 1e-20
Identities = 54/132 (40%), Positives = 79/132 (59%), Gaps = 2/132 (1%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGE-SDVNAV 395
WG GYVYQK YLEF K KL L++ K +TY A++ +S+ + S NAV
Sbjct: 270 WGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAV 329
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDP-SRKLLEEVKNSYYL 218
TWG+FP +E++Q TIV+ SF WK+E + I + N+ D P S + ++ + + Y L
Sbjct: 330 TWGIFPGREILQPTIVEKISFLAWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYCL 389
Query: 217 VSLVDNKYINGD 182
V++VDN YI+ D
Sbjct: 390 VNIVDNDYISPD 401
[128][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 103 bits (256), Expect = 1e-20
Identities = 54/132 (40%), Positives = 79/132 (59%), Gaps = 2/132 (1%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGE-SDVNAV 395
WG GYVYQK YLEF K KL L++ K +TY A++ +S+ + S NAV
Sbjct: 459 WGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAV 518
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDP-SRKLLEEVKNSYYL 218
TWG+FP +E++Q TIV+ SF WK+E + I + N+ D P S + ++ + + Y L
Sbjct: 519 TWGIFPGREILQPTIVEKISFLAWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYCL 578
Query: 217 VSLVDNKYINGD 182
V++VDN YI+ D
Sbjct: 579 VNIVDNDYISPD 590
[129][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 103 bits (256), Expect = 1e-20
Identities = 54/132 (40%), Positives = 79/132 (59%), Gaps = 2/132 (1%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGE-SDVNAV 395
WG GYVYQK YLEF K KL L++ K +TY A++ +S+ + S NAV
Sbjct: 459 WGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAV 518
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDP-SRKLLEEVKNSYYL 218
TWG+FP +E++Q TIV+ SF WK+E + I + N+ D P S + ++ + + Y L
Sbjct: 519 TWGIFPGREILQPTIVEKISFLAWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYCL 578
Query: 217 VSLVDNKYINGD 182
V++VDN YI+ D
Sbjct: 579 VNIVDNDYISPD 590
[130][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 102 bits (255), Expect = 2e-20
Identities = 55/127 (43%), Positives = 77/127 (60%), Gaps = 1/127 (0%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDV-NAV 395
WG GYV+QKAYLEFF D++ +L+E +F ++ Y + E + + GE DV +AV
Sbjct: 455 WGPAHGYVFQKAYLEFFMHPDQVKSLLEVIPSFKTVQYY-ITDYEGSLETNGELDVPSAV 513
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
TWGVFP EVIQ T+V++ASF WKDEA+ + SWA + KLL + + L
Sbjct: 514 TWGVFPNSEVIQPTVVESASFLAWKDEAYSL-GLSWAKAHSSTSAPFKLLTNIVKEWKLC 572
Query: 214 SLVDNKY 194
+VDN +
Sbjct: 573 VIVDNDF 579
[131][TOP]
>UniRef100_Q5A5S8 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5A5S8_CANAL
Length = 640
Score = 102 bits (253), Expect = 3e-20
Identities = 51/133 (38%), Positives = 77/133 (57%), Gaps = 5/133 (3%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNK-----SEKWVSSTGESD 407
WG G +YQK+++E F K+ L+ K + ++TY NK S + +
Sbjct: 498 WGPRNGIIYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVGNKDGEIKSNLPIGPNVKLS 557
Query: 406 VNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNS 227
NAVTWGVFP+KEV+Q T++D SFK W +EAF +W WA Y ++ S +LL + +
Sbjct: 558 KNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFLLW-LEWARCYKKNSKSFELLNSIYEN 616
Query: 226 YYLVSLVDNKYIN 188
Y LVS++ + +IN
Sbjct: 617 YVLVSMIHHDFIN 629
[132][TOP]
>UniRef100_C4YKV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=C4YKV3_CANAL
Length = 640
Score = 102 bits (253), Expect = 3e-20
Identities = 51/133 (38%), Positives = 77/133 (57%), Gaps = 5/133 (3%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNK-----SEKWVSSTGESD 407
WG G +YQK+++E F K+ L+ K + ++TY NK S + +
Sbjct: 498 WGPRNGIIYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVGNKDGEIKSNLPIGPNVKLS 557
Query: 406 VNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNS 227
NAVTWGVFP+KEV+Q T++D SFK W +EAF +W WA Y ++ S +LL + +
Sbjct: 558 KNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFLLW-LEWARCYKKNSKSFELLNSIYEN 616
Query: 226 YYLVSLVDNKYIN 188
Y LVS++ + +IN
Sbjct: 617 YVLVSMIHHDFIN 629
[133][TOP]
>UniRef100_B2B6X0 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B6X0_PODAN
Length = 691
Score = 102 bits (253), Expect = 3e-20
Identities = 51/143 (35%), Positives = 81/143 (56%), Gaps = 13/143 (9%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSK---AFPSITYMAVNKSEKWVSSTG----- 416
WG G+V+QKA++EFF L +K + + + A+N + +VSS
Sbjct: 542 WGPANGFVFQKAFVEFFIPSADWKVLEQKLRHPDLKDDVCFYAINAAGDFVSSDTAGSLE 601
Query: 415 -----ESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRK 251
E+ NAVTWGVFP KE++ TI++ SF+ W +EAF IW WA +Y + S K
Sbjct: 602 AEGEKEASTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWG-EWAKIYGKGSESEK 660
Query: 250 LLEEVKNSYYLVSLVDNKYINGD 182
LLE+++ +LV+++ + +I+ D
Sbjct: 661 LLEKIRGDSWLVNIIHHDFIDSD 683
[134][TOP]
>UniRef100_B2WHR5 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WHR5_PYRTR
Length = 653
Score = 101 bits (252), Expect = 4e-20
Identities = 49/130 (37%), Positives = 74/130 (56%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYV+QK ++EFF + K +A +T+ A N + + +S E VN VT
Sbjct: 518 WGPKNGYVFQKPFVEFFIPAAEFQAFKPKLQAHDQVTWFAGNAAGAFEASQ-EDGVNPVT 576
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WG F KE++ TI++A SF+ W DEAF IW + W +YP S LL E+ +LV+
Sbjct: 577 WGTFAGKEIVTPTIIEAVSFRSWLDEAFSIW-KEWQRIYPPRSGSSVLLGELSKDVWLVN 635
Query: 211 LVDNKYINGD 182
++ ++NG+
Sbjct: 636 VIWGDFVNGE 645
[135][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 101 bits (252), Expect = 4e-20
Identities = 57/146 (39%), Positives = 84/146 (57%), Gaps = 18/146 (12%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVE------KSKAFPS---ITYMAVNKSEKWVSST 419
WG GYVYQK YLEFFC KD L L+ KS+ S I+Y AV+K+ ++
Sbjct: 452 WGPKNGYVYQKQYLEFFCPKDLLPKLLHTIDSYNKSEGDASSSIISYYAVDKNGNLSTNC 511
Query: 418 GESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPED--DPSR--- 254
+ D+NAVTWGVFP +E++Q TIV+ SF WKDE + +++ W N+ + D +
Sbjct: 512 KDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFT-EWTNILQSNLVDADKDKI 570
Query: 253 ----KLLEEVKNSYYLVSLVDNKYIN 188
L+ N++ L +LV+N +I+
Sbjct: 571 SGFVDLITNFSNNFVLCNLVNNDFID 596
[136][TOP]
>UniRef100_C5GI01 Methylenetetrahydrofolate reductase n=2 Tax=Ajellomyces
dermatitidis RepID=C5GI01_AJEDR
Length = 713
Score = 101 bits (251), Expect = 5e-20
Identities = 54/154 (35%), Positives = 83/154 (53%), Gaps = 28/154 (18%)
Frame = -1
Query: 571 WGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSEKWVSSTGESD- 407
WG G G+V+QKA++EFFC+ L T+++ ++ + + A N + + SS+ +D
Sbjct: 527 WGPRGEGFVFQKAFVEFFCTAHDLKTILKPIFENHGHDELAWFATNAAGDFESSSPPTDD 586
Query: 406 -----------------------VNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWS 296
VNAVTWGVF KE++ TI++ SF+ W DEAF IW
Sbjct: 587 SANDYSGPVDVYLDSNATAGGTGVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD 646
Query: 295 RSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNKY 194
W ++P P+ KLL+++KN +LV +V KY
Sbjct: 647 -EWRRVFPRGSPTEKLLDQLKNDVWLVCVVGQKY 679
[137][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 101 bits (251), Expect = 5e-20
Identities = 55/150 (36%), Positives = 83/150 (55%), Gaps = 20/150 (13%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS---------ITYMAVNKSEKWVSST 419
WG GYVYQK YLEFFC KD + L++ + + I+Y AV+ ++
Sbjct: 453 WGPKNGYVYQKQYLEFFCHKDIIVKLLQTIDDYNNNQGDASSAIISYYAVDLKGNLTTNC 512
Query: 418 GESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSR-------SWANLYPEDDP 260
+ D+NAVTWGVFP +E++Q TIV+ SF WKDE + ++S + A++ ED
Sbjct: 513 NDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFSEWRKVLTSNLADVKDEDKK 572
Query: 259 S----RKLLEEVKNSYYLVSLVDNKYINGD 182
+ KL+ E Y L +LV+N +I+ +
Sbjct: 573 NLHKFEKLMTEFSEDYVLCNLVNNDFIDSN 602
[138][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 100 bits (250), Expect = 6e-20
Identities = 54/149 (36%), Positives = 80/149 (53%), Gaps = 21/149 (14%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS---------ITYMAVNKSEKWVSST 419
WG GYVYQK YLEFF KD + L+ + + +TY AV++ K S+T
Sbjct: 452 WGPKNGYVYQKQYLEFFVHKDIIPALLHQIDNYNRGQGDSNSSVLTYYAVDQKGKLFSNT 511
Query: 418 GESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPED--------- 266
+ D+NAVTWGVFP +E++Q TIV+ SF WKDE + + + W ++ D
Sbjct: 512 KDDDINAVTWGVFPGEEILQPTIVEKVSFLAWKDEVYRLIT-EWIKIFQSDFVKDVNITK 570
Query: 265 ---DPSRKLLEEVKNSYYLVSLVDNKYIN 188
D KL+ + Y L ++V+N +I+
Sbjct: 571 EDVDAFVKLMTNFNDEYVLCNVVNNNFID 599
[139][TOP]
>UniRef100_B9WCV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WCV3_CANDC
Length = 640
Score = 100 bits (250), Expect = 6e-20
Identities = 50/133 (37%), Positives = 77/133 (57%), Gaps = 5/133 (3%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNK-----SEKWVSSTGESD 407
WG G +YQK+++E F K+ L+ K + ++TY +K S + +
Sbjct: 498 WGPRNGTIYQKSFIELFMPKEDWTKLLLKIELDKTVTYYVGDKDGEIRSNLPIGPNAKLS 557
Query: 406 VNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNS 227
NAVTWGVFP+KEV+Q T++D SFK W +EAF +W WA Y ++ S +LL + +
Sbjct: 558 KNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFLLWV-EWARCYKKNSKSFELLNSIYEN 616
Query: 226 YYLVSLVDNKYIN 188
Y LVS++ + +IN
Sbjct: 617 YVLVSIIHHDFIN 629
[140][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 100 bits (250), Expect = 6e-20
Identities = 54/149 (36%), Positives = 80/149 (53%), Gaps = 21/149 (14%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS---------ITYMAVNKSEKWVSST 419
WG GYVYQK YLEFF KD + L+ + + +TY AV++ K S+T
Sbjct: 452 WGPKNGYVYQKQYLEFFVHKDIIPALLHQIDNYNRGQGDSNSSVLTYYAVDQKGKLFSNT 511
Query: 418 GESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPED--------- 266
+ D+NAVTWGVFP +E++Q TIV+ SF WKDE + + + W ++ D
Sbjct: 512 KDDDINAVTWGVFPGEEILQPTIVEKVSFLAWKDEVYRLIT-EWIKIFQSDFVKDVNITK 570
Query: 265 ---DPSRKLLEEVKNSYYLVSLVDNKYIN 188
D KL+ + Y L ++V+N +I+
Sbjct: 571 EDVDAFVKLMTNFNDEYVLCNVVNNNFID 599
[141][TOP]
>UniRef100_Q752W6 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q752W6_ASHGO
Length = 635
Score = 100 bits (249), Expect = 8e-20
Identities = 48/132 (36%), Positives = 74/132 (56%), Gaps = 2/132 (1%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS--ITYMAVNKSEKWVSSTGESDVNA 398
WG PGG VYQKA++E F K + + ++ P +Y + + + S+ +
Sbjct: 497 WGPPGGVVYQKAFVELFVEKARWEAELKPRLEGPDSKFSYYFGDSAGSFASNMAPESSSV 556
Query: 397 VTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYL 218
VTWGVFP +++Q TI++ SFK W+DEAF IW SW+ L+P + P L + Y L
Sbjct: 557 VTWGVFPNSQILQTTIIEEESFKAWRDEAFSIW-LSWSKLFPRNSPHNAFLRGIHRDYCL 615
Query: 217 VSLVDNKYINGD 182
VS+V + + + D
Sbjct: 616 VSIVHHDFSSVD 627
[142][TOP]
>UniRef100_C5M548 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M548_CANTT
Length = 633
Score = 100 bits (249), Expect = 8e-20
Identities = 54/127 (42%), Positives = 76/127 (59%), Gaps = 5/127 (3%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGES-DV--- 404
WG G VYQKA++E F KD + L +A SITY A +K+ K + D+
Sbjct: 491 WGPRNGVVYQKAFVELFMPKDDWNKLKPLVEASDSITYYAADKTNKIEAKVPAGHDIKLT 550
Query: 403 -NAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNS 227
NAVTWGVFP+KEV+Q T++D SFK W +E+F +W W+ Y ++ S +LL +V +
Sbjct: 551 KNAVTWGVFPSKEVLQPTVIDYESFKAWNEESFLLW-LEWSRCYKKNSKSFELLNKVYEN 609
Query: 226 YYLVSLV 206
Y LV L+
Sbjct: 610 YVLVCLI 616
[143][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1CZX0_NEOFI
Length = 716
Score = 100 bits (249), Expect = 8e-20
Identities = 53/142 (37%), Positives = 78/142 (54%), Gaps = 16/142 (11%)
Frame = -1
Query: 571 WGGPG-GYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSEKWVSST----- 419
WG PG G+V+QK ++EFFC T+++ A + + A N ++ SS
Sbjct: 550 WGPPGEGFVFQKPFVEFFCPSKDFQTVLKPLFAKHGHEKLAWFATNVKGEFESSLPADPA 609
Query: 418 -------GESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDP 260
++VNAVTWGVF KE++ TI++ SF+ W +EAF IW W +YP P
Sbjct: 610 HADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EWRRVYPRGTP 668
Query: 259 SRKLLEEVKNSYYLVSLVDNKY 194
+ +LLEEVKN +LV +V +
Sbjct: 669 TERLLEEVKNDVWLVCVVGQDF 690
[144][TOP]
>UniRef100_A5DE00 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DE00_PICGU
Length = 642
Score = 100 bits (248), Expect = 1e-19
Identities = 55/135 (40%), Positives = 78/135 (57%), Gaps = 9/135 (6%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDT-LVEKSKAFPS---ITYMAVNKSEKWVSST----- 419
WG G+V+QK+++E F K++ T L K K ITY A + S K S+
Sbjct: 497 WGPSNGFVFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDITYYAGDSSGKIQSNLPVGPD 556
Query: 418 GESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEE 239
+ NAVTWGVFP++EV+Q TI+D SF+ W +EAF +WS WA Y ++ S LL
Sbjct: 557 SHNSKNAVTWGVFPSQEVLQPTIIDIESFRAWNEEAFHLWS-EWARCYKKNSVSYNLLNS 615
Query: 238 VKNSYYLVSLVDNKY 194
+ YYLVSL+ + +
Sbjct: 616 INGDYYLVSLIYHNF 630
[145][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 99.8 bits (247), Expect = 1e-19
Identities = 53/142 (37%), Positives = 78/142 (54%), Gaps = 16/142 (11%)
Frame = -1
Query: 571 WGGPG-GYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSEKWVSST----- 419
WG PG G+V+QK ++EFFC T+++ A + + A N ++ SS
Sbjct: 523 WGPPGEGFVFQKPFVEFFCPSKDFRTVLKPLFAKHGHEKLAWFATNVKGEFESSLPADPA 582
Query: 418 -------GESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDP 260
++VNAVTWGVF KE++ TI++ SF+ W +EAF IW W +YP P
Sbjct: 583 HADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EWRRVYPRGTP 641
Query: 259 SRKLLEEVKNSYYLVSLVDNKY 194
+ +LLEEVKN +LV +V +
Sbjct: 642 TERLLEEVKNDVWLVCVVGQDF 663
[146][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 99.8 bits (247), Expect = 1e-19
Identities = 53/142 (37%), Positives = 78/142 (54%), Gaps = 16/142 (11%)
Frame = -1
Query: 571 WGGPG-GYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSEKWVSST----- 419
WG PG G+V+QK ++EFFC T+++ A + + A N ++ SS
Sbjct: 523 WGPPGEGFVFQKPFVEFFCPSKDFRTVLKPLFAKHGHEKLAWFATNVKGEFESSLPADPA 582
Query: 418 -------GESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDP 260
++VNAVTWGVF KE++ TI++ SF+ W +EAF IW W +YP P
Sbjct: 583 HADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EWRRVYPRGTP 641
Query: 259 SRKLLEEVKNSYYLVSLVDNKY 194
+ +LLEEVKN +LV +V +
Sbjct: 642 TERLLEEVKNDVWLVCVVGQDF 663
[147][TOP]
>UniRef100_A7E9M9 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7E9M9_SCLS1
Length = 663
Score = 99.4 bits (246), Expect = 2e-19
Identities = 49/134 (36%), Positives = 79/134 (58%), Gaps = 4/134 (2%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEK--SKAF-PSITYMAVNKSEKWVSSTGE-SDV 404
WG G+V+QKA++E F + L K S A ++++ A N ++SS
Sbjct: 523 WGPKNGFVFQKAFVELFLPTSDWEALQAKLTSPALRDTVSFYASNAKGDFISSDEAIGST 582
Query: 403 NAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSY 224
NAVTWG FP KE+I TI++ SF+ W +EAF IW WA +Y +D +RK+++ +K
Sbjct: 583 NAVTWGAFPGKEIITPTIIEEVSFRAWAEEAFGIWG-EWARVYGKDSETRKVIDGIKEDV 641
Query: 223 YLVSLVDNKYINGD 182
+LV+++ + Y+ G+
Sbjct: 642 WLVNVIHHAYVEGE 655
[148][TOP]
>UniRef100_A6RQJ7 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6RQJ7_BOTFB
Length = 663
Score = 99.4 bits (246), Expect = 2e-19
Identities = 48/134 (35%), Positives = 78/134 (58%), Gaps = 4/134 (2%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSEKWVSST-GESDV 404
WG G+V+QKA++E F TL K + ++++ A N ++SS
Sbjct: 523 WGPKNGFVFQKAFVELFIPVADWKTLHAKLTSPDLCDTVSFYASNAKGDFISSDEAVGST 582
Query: 403 NAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSY 224
NAVTWG FP KE+I TI++ SF+ W +EAF IW WA +Y +D +RK+++ +K
Sbjct: 583 NAVTWGAFPGKEIITPTIIEEVSFRAWAEEAFGIWG-EWARVYGKDSQTRKIIDGIKEDV 641
Query: 223 YLVSLVDNKYINGD 182
+LV+++ + Y+ G+
Sbjct: 642 WLVNVIHHAYVEGE 655
[149][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 99.0 bits (245), Expect = 2e-19
Identities = 55/131 (41%), Positives = 75/131 (57%), Gaps = 4/131 (3%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKA-FPSITYMAVNKSEKWVSS-TGESDVNA 398
WG GYVYQK YLEF K L A FP++TY AV+ + S+ ++ NA
Sbjct: 460 WGPANGYVYQKQYLEFLLPKHHLPAFHAALTADFPTLTYFAVDADDNLASNHPDDTQANA 519
Query: 397 VTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDD--PSRKLLEEVKNSY 224
VTWG+FP +EV+Q TIV+ ASF WKDE + I W + E+ S LL + + Y
Sbjct: 520 VTWGIFPGREVLQPTIVEKASFLAWKDEFYRILD-DWRLSFDENGAADSAALLAHLTSDY 578
Query: 223 YLVSLVDNKYI 191
LV++VDN ++
Sbjct: 579 ALVNIVDNDFV 589
[150][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 99.0 bits (245), Expect = 2e-19
Identities = 57/142 (40%), Positives = 83/142 (58%), Gaps = 16/142 (11%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTL---VEKSKA---FPSITYMAVNKSEKWVSSTGES 410
WG G+VYQK YLEF KDKL L VEK A + ITY AV+KS +++
Sbjct: 454 WGPKNGFVYQKQYLEFLVRKDKLKELLDIVEKHNAKDTYGLITYYAVDKSGNLHTNSKND 513
Query: 409 DVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEI---W-----SRSWANLYPEDDPSR 254
D+NAVTWGVFP +E++Q TIV+ SF WKDE + + W S++ ++ PED ++
Sbjct: 514 DINAVTWGVFPGEEILQPTIVEKVSFLAWKDEVYSLLDEWITIFHSKAITDIVPEDKINK 573
Query: 253 --KLLEEVKNSYYLVSLVDNKY 194
L++ ++ L + V+N +
Sbjct: 574 FDDLIKSFGENFVLCNFVNNDF 595
[151][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 98.6 bits (244), Expect = 3e-19
Identities = 53/139 (38%), Positives = 84/139 (60%), Gaps = 5/139 (3%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGE-SDVNAV 395
WG GYVYQK YLEF +K++ L ++ +TY AV+ + S+ + S NAV
Sbjct: 459 WGPKDGYVYQKQYLEFLLPNEKVEKLEKQLAGNEMLTYFAVDNKDNLKSNHPDGSKANAV 518
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDD--PSRKLLEEVKNSYY 221
TWG+FP +EV+Q TIV+ SF WK+E + I W + E++ S + ++ + ++Y
Sbjct: 519 TWGIFPGREVLQPTIVEKVSFLAWKEEFYRI-LEEWKWNFQENNELKSAEFIQHIIDNYM 577
Query: 220 LVSLVDNKYING--DIFSV 170
LV++VDN YI+ +I++V
Sbjct: 578 LVNIVDNDYISSTDEIYNV 596
[152][TOP]
>UniRef100_C4R2L4 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2L4_PICPG
Length = 596
Score = 98.6 bits (244), Expect = 3e-19
Identities = 49/130 (37%), Positives = 79/130 (60%), Gaps = 2/130 (1%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKL-DTLVEKSKAFPSITYMAVNKSEKWVSSTG-ESDVNA 398
WG GYVYQKA++E F +K + + ++ + S+T+ + + + ++ N+
Sbjct: 457 WGPSEGYVYQKAFVEVFINKKQWNEEILPNLQGHKSVTWYLGDCNNAFDTNIKIPLSSNS 516
Query: 397 VTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYL 218
VTWG FP KE++Q TI+ SF+ W +EAF IW R W LYP++ S LL + N++YL
Sbjct: 517 VTWGCFPDKEIVQTTIIGEESFQAWNEEAFNIW-REWQKLYPKNTASYNLLGSIINNFYL 575
Query: 217 VSLVDNKYIN 188
V+L+++ Y N
Sbjct: 576 VTLINHDYAN 585
[153][TOP]
>UniRef100_Q1DT03 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DT03_COCIM
Length = 711
Score = 97.8 bits (242), Expect = 5e-19
Identities = 56/155 (36%), Positives = 79/155 (50%), Gaps = 29/155 (18%)
Frame = -1
Query: 571 WGGPG-GYVYQKAYLEFFCSKDK----LDTLVEKSKAFPSITYMAVNKSEKWVSSTGES- 410
WG PG G+V+QKA++EFFCSKD L L+++ + A N + + SST S
Sbjct: 529 WGPPGEGFVFQKAFVEFFCSKDDYRSHLKPLLQRY-GHDEFAWFATNAAGDFESSTSSSI 587
Query: 409 -----------------------DVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIW 299
VNAVTWGVF KE+I TI++ SF+ W +EAF IW
Sbjct: 588 PVPTGPVDAVFDDMDSFPSSNSGGVNAVTWGVFRGKEIITPTIIEEVSFRAWGEEAFRIW 647
Query: 298 SRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNKY 194
W ++P P+ KLL VK +LV ++ ++
Sbjct: 648 D-EWRRIFPRGSPTEKLLNRVKEDTWLVCVIGQRF 681
[154][TOP]
>UniRef100_C5P4Q4 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5P4Q4_COCP7
Length = 711
Score = 97.8 bits (242), Expect = 5e-19
Identities = 56/155 (36%), Positives = 79/155 (50%), Gaps = 29/155 (18%)
Frame = -1
Query: 571 WGGPG-GYVYQKAYLEFFCSKDK----LDTLVEKSKAFPSITYMAVNKSEKWVSSTGES- 410
WG PG G+V+QKA++EFFCSKD L L+++ + A N + + SST S
Sbjct: 529 WGPPGEGFVFQKAFVEFFCSKDDYRSHLKPLLQRY-GHDEFAWFATNAAGDFESSTSSSI 587
Query: 409 -----------------------DVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIW 299
VNAVTWGVF KE+I TI++ SF+ W +EAF IW
Sbjct: 588 PVPTGPVDAVFDDMDSFPSSNSGGVNAVTWGVFRGKEIITPTIIEEVSFRAWGEEAFRIW 647
Query: 298 SRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNKY 194
W ++P P+ KLL VK +LV ++ ++
Sbjct: 648 D-EWRRIFPRGSPTEKLLNRVKEDTWLVCVIGQRF 681
[155][TOP]
>UniRef100_C5DPF1 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5DPF1_ZYGRC
Length = 650
Score = 97.8 bits (242), Expect = 5e-19
Identities = 52/135 (38%), Positives = 74/135 (54%), Gaps = 5/135 (3%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKD-----KLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESD 407
WG G VYQKA++E F K+ + +E+ +TY A + + ++ +
Sbjct: 510 WGPAYGVVYQKAFIEMFVPKNIWENGNMKKAIEQYGR-AKLTYYANDSQGNFETNLESNS 568
Query: 406 VNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNS 227
N VTWGVF +VIQ+TIV SFK W DEAF IW WA L+P + + LL ++
Sbjct: 569 SNVVTWGVFSDSQVIQSTIVSEESFKAWSDEAFSIW-LEWAKLFPRNTSTNSLLRQIHQE 627
Query: 226 YYLVSLVDNKYINGD 182
Y L+S+V + YIN D
Sbjct: 628 YCLISIVHHDYINPD 642
[156][TOP]
>UniRef100_Q7S2B6 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S2B6_NEUCR
Length = 681
Score = 97.4 bits (241), Expect = 7e-19
Identities = 54/155 (34%), Positives = 83/155 (53%), Gaps = 25/155 (16%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSEKWVSS------- 422
WG G+V+QKA++EFF L K K ++ + A N + +VS+
Sbjct: 520 WGPENGFVFQKAFVEFFIPSADWRVLEAKLKQPDMKDTVCFFATNAAGDFVSTDTINFRA 579
Query: 421 --------TGESD-------VNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSW 287
T E+D NAVTWGVFP KE++ TI++ SF+ W +EAF IWS W
Sbjct: 580 RMAAEAEGTAEADHRPHEPSTNAVTWGVFPGKEILTPTIIEEVSFRAWSEEAFGIWS-EW 638
Query: 286 ANLYPEDDPSRKLLEEVKNSYYLVSLVDNKYINGD 182
A +Y + ++KLLE++K +LV+++ + Y+ D
Sbjct: 639 AKIYGKGSDTQKLLEDLKEDLWLVNVIHHDYLEKD 673
[157][TOP]
>UniRef100_C9S7I3 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S7I3_9PEZI
Length = 312
Score = 97.4 bits (241), Expect = 7e-19
Identities = 46/105 (43%), Positives = 60/105 (57%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG GYVYQK+YLE D ++ + + P +TY AV KS + NAVT
Sbjct: 155 WGPKNGYVYQKSYLEMLVHPDLYPEIISRIEKHPDMTYYAVTKSGNLKYNAPSDGPNAVT 214
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPS 257
WGVFP KE++Q TIV+ SF WKDEAF + WA+ + + PS
Sbjct: 215 WGVFPGKEIVQPTIVEGISFVAWKDEAFRL-GLDWAHCFEQSSPS 258
[158][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 97.4 bits (241), Expect = 7e-19
Identities = 50/129 (38%), Positives = 80/129 (62%), Gaps = 3/129 (2%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS-ITYMAVNKSEKWVSSTG--ESDVN 401
+G GGY++QKA++E F +++ + LV+ + + +TY A K + T + +N
Sbjct: 449 FGPQGGYIFQKAFVELFMNENDKNALVQMIQGSSTPVTYFA-GKCDPTTFETNLTTNGLN 507
Query: 400 AVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYY 221
VTWGVFP EV Q+TI++ ASF+ W+DEAF IW R W L+P + +R LL + + +
Sbjct: 508 TVTWGVFPGTEVAQSTIIEEASFRAWRDEAFAIW-REWELLFPPNSATRSLLRRIHDERW 566
Query: 220 LVSLVDNKY 194
LV++V + Y
Sbjct: 567 LVTVVHHDY 575
[159][TOP]
>UniRef100_A4RH85 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RH85_MAGGR
Length = 662
Score = 97.4 bits (241), Expect = 7e-19
Identities = 53/150 (35%), Positives = 77/150 (51%), Gaps = 23/150 (15%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT-YMAVNKSEKWVSSTGESDV--- 404
WG G+V+QKA++E F L EK + + + A N + SS G D
Sbjct: 503 WGPQNGFVFQKAFVEMFLPSKDWKALREKLLSEKDVVCFYASNAKGDFESSDGGGDAPDG 562
Query: 403 -------------------NAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWAN 281
NAVTWGVFP KE++ TI++ SF+ W +EAF IW+ WA
Sbjct: 563 APTGNGFADEQPLPSGSSTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWA-EWAK 621
Query: 280 LYPEDDPSRKLLEEVKNSYYLVSLVDNKYI 191
+Y +D PS KLLE ++ +LV+++ + YI
Sbjct: 622 VYGKDSPSEKLLESLRADLWLVNIIHHDYI 651
[160][TOP]
>UniRef100_UPI000151A866 hypothetical protein PGUG_01501 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151A866
Length = 642
Score = 97.1 bits (240), Expect = 9e-19
Identities = 54/135 (40%), Positives = 76/135 (56%), Gaps = 9/135 (6%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDT-LVEKSKAFPS---ITYMAVNKSEKWVSST----- 419
WG G+V+QK+++E F K++ T L K K ITY A + S K S+
Sbjct: 497 WGPSNGFVFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDITYYAGDSSGKIQSNLPVGPD 556
Query: 418 GESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEE 239
+ NAVTWGVFP +EV+Q TI+D SF+ W +EAF +W WA Y ++ S LL
Sbjct: 557 SHNSKNAVTWGVFPLQEVLQPTIIDIESFRAWNEEAFHLW-LEWARCYKKNSVSYNLLNS 615
Query: 238 VKNSYYLVSLVDNKY 194
+ YYLVSL+ + +
Sbjct: 616 INGDYYLVSLIYHNF 630
[161][TOP]
>UniRef100_C0NTN2 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NTN2_AJECG
Length = 713
Score = 97.1 bits (240), Expect = 9e-19
Identities = 50/154 (32%), Positives = 81/154 (52%), Gaps = 28/154 (18%)
Frame = -1
Query: 571 WGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSEKWVSST----- 419
WG G G+V+QKA++EFFC +++++ +S + + A N + ++SS+
Sbjct: 527 WGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNAAGDFMSSSPATDA 586
Query: 418 -------------------GESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWS 296
G + V AVTWGVF KE++ TI++ SF+ W DEAF IW
Sbjct: 587 TTEDSSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD 646
Query: 295 RSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNKY 194
W ++P P+ +LL+++KN +L+ V KY
Sbjct: 647 -EWRRIFPRGSPTERLLDQLKNDVWLICCVGQKY 679
[162][TOP]
>UniRef100_A6QT35 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6QT35_AJECN
Length = 712
Score = 97.1 bits (240), Expect = 9e-19
Identities = 50/154 (32%), Positives = 81/154 (52%), Gaps = 28/154 (18%)
Frame = -1
Query: 571 WGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSEKWVSST----- 419
WG G G+V+QKA++EFFC +++++ +S + + A N + ++SS+
Sbjct: 526 WGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNAAGDFMSSSPATDA 585
Query: 418 -------------------GESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWS 296
G + V AVTWGVF KE++ TI++ SF+ W DEAF IW
Sbjct: 586 ATEDFSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD 645
Query: 295 RSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNKY 194
W ++P P+ +LL+++KN +L+ V KY
Sbjct: 646 -EWRRIFPRGSPTERLLDQLKNDVWLICCVGQKY 678
[163][TOP]
>UniRef100_C6HED8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6HED8_AJECH
Length = 713
Score = 96.7 bits (239), Expect = 1e-18
Identities = 50/154 (32%), Positives = 81/154 (52%), Gaps = 28/154 (18%)
Frame = -1
Query: 571 WGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSEKWVSST----- 419
WG G G+V+QKA++EFFC +++++ +S + + A N + ++SS+
Sbjct: 527 WGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNVAGDFMSSSPATDA 586
Query: 418 -------------------GESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWS 296
G + V AVTWGVF KE++ TI++ SF+ W DEAF IW
Sbjct: 587 TTEDSSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD 646
Query: 295 RSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNKY 194
W ++P P+ +LL+++KN +L+ V KY
Sbjct: 647 -EWRRIFPRGSPTERLLDQLKNDVWLICCVGQKY 679
[164][TOP]
>UniRef100_Q6BM19 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=Q6BM19_DEBHA
Length = 642
Score = 96.3 bits (238), Expect = 1e-18
Identities = 52/135 (38%), Positives = 75/135 (55%), Gaps = 9/135 (6%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKD----KLDTLVEKSKAFPSITYMAVNKSEKWVSSTG---- 416
WG G +YQKA++E F KD KL ++K +ITY + + S+
Sbjct: 495 WGPGNGIIYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTITYYCGDAEGRLTSNLNIDQE 554
Query: 415 -ESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEE 239
+ NA+TWGVFP+KEV+Q TI+D SFK W +EAF +W WA Y + + +LL
Sbjct: 555 HYNSKNAITWGVFPSKEVLQPTIIDLESFKAWNEEAFILW-LEWARCYKKTSKTYELLNS 613
Query: 238 VKNSYYLVSLVDNKY 194
+ YYLVSL+ + +
Sbjct: 614 IYKDYYLVSLISHDF 628
[165][TOP]
>UniRef100_Q0CE17 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CE17_ASPTN
Length = 696
Score = 95.9 bits (237), Expect = 2e-18
Identities = 51/142 (35%), Positives = 76/142 (53%), Gaps = 16/142 (11%)
Frame = -1
Query: 571 WGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSEKWVSS----TG 416
WG P G+V+QK ++EFFC T ++ + + + A N + + SS T
Sbjct: 531 WGPPREGFVFQKPFVEFFCPTKDYQTALKPMLQKHGHEKLAWFATNANGDFESSLPAQTS 590
Query: 415 ESD--------VNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDP 260
++D VNAVTWGVF KE++ TI++ SF+ W DEA+ IW W +YP P
Sbjct: 591 DADPIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWD-EWRRIYPRGSP 649
Query: 259 SRKLLEEVKNSYYLVSLVDNKY 194
+ + LEE KN +LV +V +
Sbjct: 650 TERFLEETKNDVWLVCVVGQDF 671
[166][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TTE9_VANPO
Length = 612
Score = 95.9 bits (237), Expect = 2e-18
Identities = 53/149 (35%), Positives = 83/149 (55%), Gaps = 19/149 (12%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEK----SKAFPSITYMAVNKSEKWVSSTGE-SD 407
WG GYVYQK YLEF + + + L ++ ++ S+TY+A + W S+ + +
Sbjct: 454 WGPSDGYVYQKQYLEFLLPRARFERLQQELSKTNETTSSLTYLAADSHGGWWSNQPDGAK 513
Query: 406 VNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEI---WSRSWANLYPEDD--------- 263
AVTWGVFP +EV+Q TIV+ SF W+DE + I W + + P+ D
Sbjct: 514 ATAVTWGVFPGREVLQPTIVEKISFLAWRDEFYRILQDWRDIFVHASPDGDQCDNGSAQR 573
Query: 262 --PSRKLLEEVKNSYYLVSLVDNKYINGD 182
PS KL++ + + Y LV+L+DN +++ D
Sbjct: 574 ENPSAKLMQLMIDDYVLVNLIDNDFVSVD 602
[167][TOP]
>UniRef100_A1C4Z1 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C4Z1_ASPCL
Length = 690
Score = 95.9 bits (237), Expect = 2e-18
Identities = 49/142 (34%), Positives = 78/142 (54%), Gaps = 16/142 (11%)
Frame = -1
Query: 571 WGGPG-GYVYQKAYLEFFCSKDKLDTLVEK---SKAFPSITYMAVNKSEKWVSS----TG 416
WG PG G+V+QK ++EFFC +T+++ + + + A N ++ SS T
Sbjct: 524 WGPPGEGFVFQKPFVEFFCPSKDFETVLKPLFANHGHEKLAWFATNAKGEFQSSLPAETA 583
Query: 415 ESD--------VNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDP 260
+SD VNAVTWGVF KE++ TI++ SF+ W +EA+ IW W +YP
Sbjct: 584 DSDALEPNPDNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAYRIW-EEWRRIYPRGSA 642
Query: 259 SRKLLEEVKNSYYLVSLVDNKY 194
+ + ++E KN +LV +V +
Sbjct: 643 TERFIDETKNDVWLVCVVGQDF 664
[168][TOP]
>UniRef100_UPI00003BE162 hypothetical protein DEHA0F09867g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE162
Length = 642
Score = 95.5 bits (236), Expect = 3e-18
Identities = 52/135 (38%), Positives = 74/135 (54%), Gaps = 9/135 (6%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKD----KLDTLVEKSKAFPSITYMAVNKSEKWVSSTG---- 416
WG G +YQKA++E F KD KL ++K +ITY + + S+
Sbjct: 495 WGPGNGIIYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTITYYCGDAEGRLTSNLNIDQE 554
Query: 415 -ESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEE 239
+ NA+TWGVFP KEV+Q TI+D SFK W +EAF +W WA Y + + +LL
Sbjct: 555 HYNSKNAITWGVFPLKEVLQPTIIDLESFKAWNEEAFILW-LEWARCYKKTSKTYELLNS 613
Query: 238 VKNSYYLVSLVDNKY 194
+ YYLVSL+ + +
Sbjct: 614 IYKDYYLVSLISHDF 628
[169][TOP]
>UniRef100_C8V780 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5AU15] n=2 Tax=Emericella
nidulans RepID=C8V780_EMENI
Length = 684
Score = 95.5 bits (236), Expect = 3e-18
Identities = 49/142 (34%), Positives = 75/142 (52%), Gaps = 16/142 (11%)
Frame = -1
Query: 571 WGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSEKWVSST----- 419
WG PG G+V+QK ++EFFC T ++ + + + A N + + SS
Sbjct: 519 WGPPGEGFVFQKPFVEFFCPASDFKTTLKPLLQKHGHEKLAWFATNAAGDFESSLPAETS 578
Query: 418 -------GESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDP 260
++VNAVTWGVF KE++ TI++ SF+ W DEA+ IW W +YP+
Sbjct: 579 DTEPVEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWD-EWRRIYPKSSA 637
Query: 259 SRKLLEEVKNSYYLVSLVDNKY 194
+ K LE+ KN +LV +V +
Sbjct: 638 TEKFLEKTKNDVWLVCVVGQDF 659
[170][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 95.1 bits (235), Expect = 3e-18
Identities = 54/132 (40%), Positives = 76/132 (57%), Gaps = 4/132 (3%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESD-VNAV 395
WG GYVYQK YLEF K+KL L + +TY AV+ + ++ + NAV
Sbjct: 458 WGPRDGYVYQKMYLEFLLPKEKLSKLHDCLVNDVMLTYFAVDHNGNLTTNHQDGTRANAV 517
Query: 394 TWGVFPAKEVIQATIVDAASFKVWKDEAFEI---WSRSWANLYPEDDPSRKLLEEVKNSY 224
TWG+FP +EV+Q TIV+ SF WK E + I W ++ N D S KLL+ + + Y
Sbjct: 518 TWGIFPGREVLQPTIVEKVSFLAWKQEFYHICEEWKLNFIN--HRCDQSVKLLQHLIDDY 575
Query: 223 YLVSLVDNKYIN 188
LV++VDN +I+
Sbjct: 576 VLVNIVDNDFIS 587
[171][TOP]
>UniRef100_A3LW82 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LW82_PICST
Length = 635
Score = 95.1 bits (235), Expect = 3e-18
Identities = 52/136 (38%), Positives = 80/136 (58%), Gaps = 10/136 (7%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-----SITYMAVN-----KSEKWVSS 422
WG G VYQKA++E F K++ ++ + KS P +ITY + +S +V
Sbjct: 490 WGPKNGIVYQKAFVEIFVPKEQWESEL-KSSLKPHFEEKTITYYVGDAEGNIESNLFVGP 548
Query: 421 TGESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
+ NA+TWGVFP+KEV+Q TI+D SFK W +EAF +W WA Y ++ + +LL
Sbjct: 549 DAHNSKNAITWGVFPSKEVLQPTIIDYESFKAWNEEAFLLWI-EWARCYKKNTKTFQLLN 607
Query: 241 EVKNSYYLVSLVDNKY 194
+ ++Y LVSL+ + +
Sbjct: 608 SIYSNYVLVSLIHHDF 623
[172][TOP]
>UniRef100_A5DZ35 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DZ35_LODEL
Length = 622
Score = 94.4 bits (233), Expect = 6e-18
Identities = 54/131 (41%), Positives = 76/131 (58%), Gaps = 5/131 (3%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSS--TGESD--- 407
WG G VYQK+++E F L K + + TY +KS + S T ES
Sbjct: 483 WGPGNGVVYQKSFVELFIPAKDWKEL--KPRLDDATTYYVGDKSGRIELSLFTNESTRHL 540
Query: 406 VNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNS 227
NAVTWGVFP KEV+Q T++D SFK W +EAF +W WA Y ++ + +LL V+++
Sbjct: 541 KNAVTWGVFPLKEVVQPTVIDYESFKAWNEEAFLLW-LEWARCYKKNSKTYELLNSVRDN 599
Query: 226 YYLVSLVDNKY 194
Y LVSL+ ++Y
Sbjct: 600 YVLVSLIHHEY 610
[173][TOP]
>UniRef100_A2QUJ5 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QUJ5_ASPNC
Length = 699
Score = 94.4 bits (233), Expect = 6e-18
Identities = 50/143 (34%), Positives = 79/143 (55%), Gaps = 17/143 (11%)
Frame = -1
Query: 571 WGGPG-GYVYQKAYLEFFC-SKDKLDTL--VEKSKAFPSITYMAVNKSEKWVSST----- 419
WG PG G+V+QK ++EFFC +KD L L + + + + A N + SS
Sbjct: 532 WGPPGEGFVFQKPFVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNVKGDFESSLPGPNT 591
Query: 418 --------GESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDD 263
++VNAVTWGVF KE++ TI++ SF+ W DEA+ IW W +YP++
Sbjct: 592 DDPDPIDINPANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWD-EWRRIYPKNS 650
Query: 262 PSRKLLEEVKNSYYLVSLVDNKY 194
+ + L++ KN +LV +V ++
Sbjct: 651 ATERFLDDTKNDVWLVCVVGQEF 673
[174][TOP]
>UniRef100_C1H0K0 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1H0K0_PARBA
Length = 713
Score = 94.0 bits (232), Expect = 7e-18
Identities = 53/149 (35%), Positives = 80/149 (53%), Gaps = 23/149 (15%)
Frame = -1
Query: 571 WGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSEKWVSS------ 422
WG G G+V+QKA++EFFCS + +++ K +++ A N S + SS
Sbjct: 531 WGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQSSSSFTGI 590
Query: 421 TGESD-------------VNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWAN 281
TG D VNAVTWGVF KE+I TI++ SF+ W DEAF IW W
Sbjct: 591 TGLDDAVPDYNGAASSNGVNAVTWGVFKGKEIITPTIIEEVSFRAWGDEAFRIWD-EWRR 649
Query: 280 LYPEDDPSRKLLEEVKNSYYLVSLVDNKY 194
++ P+ +LL+++K +L+ +V K+
Sbjct: 650 IFRRGSPTEQLLDQLKKDAWLICVVGQKF 678
[175][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 92.8 bits (229), Expect = 2e-17
Identities = 52/132 (39%), Positives = 76/132 (57%), Gaps = 4/132 (3%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS-ITYMAVNKSEKWVSSTGE-SDVNA 398
WG GYVYQK YLEF ++KL E + +TY A++ + ++ E S NA
Sbjct: 461 WGPTKGYVYQKEYLEFLLPREKLPLFQEICQEHSDHLTYFAIDSQDNLATNHPEDSRANA 520
Query: 397 VTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPED--DPSRKLLEEVKNSY 224
VTWGVFP E++Q TIV+ ASF WK+E F I + W + E S L+ + ++Y
Sbjct: 521 VTWGVFPGSEILQPTIVEKASFLAWKEEFFTI-LKEWKLTFVEHKATESVNLVNHIIDNY 579
Query: 223 YLVSLVDNKYIN 188
L+++VDN +I+
Sbjct: 580 VLINVVDNDFIS 591
[176][TOP]
>UniRef100_C7GU28 Met12p n=2 Tax=Saccharomyces cerevisiae RepID=C7GU28_YEAS2
Length = 657
Score = 92.0 bits (227), Expect = 3e-17
Identities = 49/133 (36%), Positives = 72/133 (54%), Gaps = 3/133 (2%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF---PSITYMAVNKSEKWVSSTGESDVN 401
WG G +YQKA++E F + + +T ++ +Y A + S + ++ +
Sbjct: 516 WGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSS 575
Query: 400 AVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYY 221
VTWGVFP V Q TI++ SFK W+DEAF IWS WA L+P + P+ LL V Y
Sbjct: 576 VVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPANILLRLVHKDYC 634
Query: 220 LVSLVDNKYINGD 182
LVS+V + + D
Sbjct: 635 LVSIVHHDFKETD 647
[177][TOP]
>UniRef100_B5VTD9 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VTD9_YEAS6
Length = 657
Score = 92.0 bits (227), Expect = 3e-17
Identities = 49/133 (36%), Positives = 72/133 (54%), Gaps = 3/133 (2%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF---PSITYMAVNKSEKWVSSTGESDVN 401
WG G +YQKA++E F + + +T ++ +Y A + S + ++ +
Sbjct: 516 WGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSS 575
Query: 400 AVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYY 221
VTWGVFP V Q TI++ SFK W+DEAF IWS WA L+P + P+ LL V Y
Sbjct: 576 VVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPANILLRLVHKDYC 634
Query: 220 LVSLVDNKYINGD 182
LVS+V + + D
Sbjct: 635 LVSIVHHDFKETD 647
[178][TOP]
>UniRef100_B3LL40 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LL40_YEAS1
Length = 657
Score = 92.0 bits (227), Expect = 3e-17
Identities = 49/133 (36%), Positives = 72/133 (54%), Gaps = 3/133 (2%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF---PSITYMAVNKSEKWVSSTGESDVN 401
WG G +YQKA++E F + + +T ++ +Y A + S + ++ +
Sbjct: 516 WGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSS 575
Query: 400 AVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYY 221
VTWGVFP V Q TI++ SFK W+DEAF IWS WA L+P + P+ LL V Y
Sbjct: 576 VVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPANILLRLVHKDYC 634
Query: 220 LVSLVDNKYINGD 182
LVS+V + + D
Sbjct: 635 LVSIVHHDFKETD 647
[179][TOP]
>UniRef100_P46151 Methylenetetrahydrofolate reductase 1 n=1 Tax=Saccharomyces
cerevisiae RepID=MTHR1_YEAST
Length = 657
Score = 92.0 bits (227), Expect = 3e-17
Identities = 49/133 (36%), Positives = 72/133 (54%), Gaps = 3/133 (2%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF---PSITYMAVNKSEKWVSSTGESDVN 401
WG G +YQKA++E F + + +T ++ +Y A + S + ++ +
Sbjct: 516 WGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSS 575
Query: 400 AVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYY 221
VTWGVFP V Q TI++ SFK W+DEAF IWS WA L+P + P+ LL V Y
Sbjct: 576 VVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPANILLRLVHKDYC 634
Query: 220 LVSLVDNKYINGD 182
LVS+V + + D
Sbjct: 635 LVSIVHHDFKETD 647
[180][TOP]
>UniRef100_C1GJU2 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1GJU2_PARBD
Length = 712
Score = 91.3 bits (225), Expect = 5e-17
Identities = 52/149 (34%), Positives = 79/149 (53%), Gaps = 23/149 (15%)
Frame = -1
Query: 571 WGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSEKWVSS------ 422
WG G G+V+QKA++EFFCS + +++ K +++ A N S + SS
Sbjct: 531 WGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQSSSSFTGT 590
Query: 421 TGESD-------------VNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWAN 281
TG D VNAVTWGVF KE+I TI++ SF+ W EAF IW W
Sbjct: 591 TGLDDAVPDYNGAASSNGVNAVTWGVFKGKEIITPTIIEEVSFRAWGHEAFRIWD-EWRR 649
Query: 280 LYPEDDPSRKLLEEVKNSYYLVSLVDNKY 194
++ P+ +LL+++K +L+ +V K+
Sbjct: 650 IFRRGSPTEQLLDQLKKDAWLICVVGQKF 678
[181][TOP]
>UniRef100_C0S8C4 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0S8C4_PARBP
Length = 712
Score = 91.3 bits (225), Expect = 5e-17
Identities = 52/149 (34%), Positives = 79/149 (53%), Gaps = 23/149 (15%)
Frame = -1
Query: 571 WGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSEKWVSS------ 422
WG G G+V+QKA++EFFCS + +++ K +++ A N S + SS
Sbjct: 531 WGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQSSSSFTGT 590
Query: 421 TGESD-------------VNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWAN 281
TG D VNAVTWGVF KE+I TI++ SF+ W EAF IW W
Sbjct: 591 TGLDDAVPDYSGAASSNGVNAVTWGVFKGKEIITPTIIEEVSFRAWGHEAFRIWD-EWRR 649
Query: 280 LYPEDDPSRKLLEEVKNSYYLVSLVDNKY 194
++ P+ +LL+++K +L+ +V K+
Sbjct: 650 IFRRGSPTEQLLDQLKKDAWLICVVGQKF 678
[182][TOP]
>UniRef100_C9S8T9 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S8T9_9PEZI
Length = 670
Score = 90.5 bits (223), Expect = 8e-17
Identities = 46/139 (33%), Positives = 75/139 (53%), Gaps = 12/139 (8%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEK---SKAFPSITYMAVNKSEKWVSSTGE---- 413
WG G+V+QKA++E F L E+ + ++ + A N + + +S
Sbjct: 522 WGPSHGFVFQKAFVELFLPAADWKVLSERLTGPEVEGTVCFYACNGNGDFATSDDSGGLV 581
Query: 412 -----SDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKL 248
+ NAVTWGVFP KE+I TI++ SF+ W +EAF+IW W+ +Y S K
Sbjct: 582 RTAVPASTNAVTWGVFPGKEIITPTIIEEVSFRAWSEEAFKIWG-EWSRVYGRGHESEKF 640
Query: 247 LEEVKNSYYLVSLVDNKYI 191
L+ VK Y+LV+++ + ++
Sbjct: 641 LKTVKEEYWLVNIIHHDFV 659
[183][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 90.5 bits (223), Expect = 8e-17
Identities = 51/155 (32%), Positives = 76/155 (49%), Gaps = 29/155 (18%)
Frame = -1
Query: 571 WGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSEKWVSSTG---- 416
WG G G+V+QKA++EFFC D + ++ S + A+N + SST
Sbjct: 488 WGPRGEGFVFQKAFVEFFCPGDDFHSKLKPLLNSYGHDEFAWFAMNAKGDFQSSTSPEPP 547
Query: 415 ---------------------ESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIW 299
VNAVTWGVF KE++ TI++A SF+ W +EAF IW
Sbjct: 548 ASPPTDSTEPLFDTDPLTDMDNGSVNAVTWGVFRGKEIVTPTIIEAVSFRAWGEEAFGIW 607
Query: 298 SRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNKY 194
W ++P S KL+ +VK+ +LV +V ++
Sbjct: 608 -EEWRRIFPRGSASEKLIRDVKDDVWLVCVVGQRF 641
[184][TOP]
>UniRef100_Q2UA39 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus oryzae
RepID=Q2UA39_ASPOR
Length = 690
Score = 89.0 bits (219), Expect = 2e-16
Identities = 52/143 (36%), Positives = 78/143 (54%), Gaps = 17/143 (11%)
Frame = -1
Query: 571 WGGPG-GYVYQKAYLEFFC-SKDK---LDTLVEKSKAFPSITYMAVNKSEKWVSS----T 419
WG P G+V+QK ++EFFC SKD L L++K + + A N + SS T
Sbjct: 523 WGPPREGFVFQKPFVEFFCPSKDYHSILKPLLQKH-GHEKLAWFAANVKGDFESSLPAQT 581
Query: 418 GESD--------VNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDD 263
++D VN VTWGVF KE++ TI++ SF+ W DEAF IW W +YP +
Sbjct: 582 SDADPIEMNPNNVNCVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD-EWRRIYPRNS 640
Query: 262 PSRKLLEEVKNSYYLVSLVDNKY 194
+ + L ++K+ +LV +V +
Sbjct: 641 ATERFLNDIKDDVWLVCVVGQDF 663
[185][TOP]
>UniRef100_B8NQE8 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus flavus
NRRL3357 RepID=B8NQE8_ASPFN
Length = 738
Score = 89.0 bits (219), Expect = 2e-16
Identities = 52/143 (36%), Positives = 78/143 (54%), Gaps = 17/143 (11%)
Frame = -1
Query: 571 WGGPG-GYVYQKAYLEFFC-SKDK---LDTLVEKSKAFPSITYMAVNKSEKWVSS----T 419
WG P G+V+QK ++EFFC SKD L L++K + + A N + SS T
Sbjct: 571 WGPPREGFVFQKPFVEFFCPSKDYHSILKPLLQKH-GHEKLAWFAANVKGDFESSLPAQT 629
Query: 418 GESD--------VNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDD 263
++D VN VTWGVF KE++ TI++ SF+ W DEAF IW W +YP +
Sbjct: 630 SDADPIEMNPNNVNCVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD-EWRRIYPRNS 688
Query: 262 PSRKLLEEVKNSYYLVSLVDNKY 194
+ + L ++K+ +LV +V +
Sbjct: 689 ATERFLNDIKDDVWLVCVVGQDF 711
[186][TOP]
>UniRef100_C4JM22 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JM22_UNCRE
Length = 709
Score = 88.6 bits (218), Expect = 3e-16
Identities = 50/154 (32%), Positives = 76/154 (49%), Gaps = 28/154 (18%)
Frame = -1
Query: 571 WGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSEKWVSSTGES-- 410
WG PG G+V+QKA++EFFCS + + ++ + + A N + + +ST S
Sbjct: 527 WGPPGEGFVFQKAFVEFFCSSNDYRSYLKPLLQRYGHDEFAWFATNAAGDFEASTPPSAH 586
Query: 409 ----------------------DVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWS 296
VNAVTWGVF KE+I TI++ SF+ W +EAF IW
Sbjct: 587 SPTEPVDAGFEDPSSPAASNPGGVNAVTWGVFRGKEIITPTIIEEVSFRAWGEEAFRIWD 646
Query: 295 RSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNKY 194
W ++ P+ KLL + K +LV +V ++
Sbjct: 647 -EWRRIFARGSPTEKLLAQTKEDVWLVCVVGQRF 679
[187][TOP]
>UniRef100_B6HK87 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6HK87_PENCW
Length = 691
Score = 88.2 bits (217), Expect = 4e-16
Identities = 46/138 (33%), Positives = 71/138 (51%), Gaps = 17/138 (12%)
Frame = -1
Query: 556 GYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSEKWVSS------------ 422
G+V+QK ++EFFCS + +++ A +T+ A N + SS
Sbjct: 528 GFVFQKPFVEFFCSSNDYTNILKPLFAKHGHDKLTWFATNVKGDFESSLPAQPADMDLDD 587
Query: 421 --TGESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKL 248
+ VNAVTWGVF KE++ TI++ SF+ W +EAF IW W +YP P+
Sbjct: 588 LGSNPESVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EWRRIYPRGSPTETY 646
Query: 247 LEEVKNSYYLVSLVDNKY 194
L+ KN +LV +V ++
Sbjct: 647 LDTTKNDSWLVCVVGQQF 664
[188][TOP]
>UniRef100_Q2HBA5 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2HBA5_CHAGB
Length = 643
Score = 87.8 bits (216), Expect = 5e-16
Identities = 43/130 (33%), Positives = 69/130 (53%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSEKWVSSTGESDVNAVT 392
WG G+V+QKA++EFF L ++ +N+ E E+ NAV+
Sbjct: 524 WGPQNGFVFQKAFVEFFLPLADWAALEKR-----------LNRPEMEGRREREASTNAVS 572
Query: 391 WGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVS 212
WGVFP KE++ TI++ SF+ W +EAF IW W +Y + S + LE V +LV+
Sbjct: 573 WGVFPGKEIVPPTIIEEVSFRAWSEEAFGIWG-EWVKIYEKGSESERFLERVLADTWLVN 631
Query: 211 LVDNKYINGD 182
++ + ++ D
Sbjct: 632 IIHHDFLETD 641
[189][TOP]
>UniRef100_B8MDD4 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8MDD4_TALSN
Length = 713
Score = 85.9 bits (211), Expect = 2e-15
Identities = 52/162 (32%), Positives = 77/162 (47%), Gaps = 31/162 (19%)
Frame = -1
Query: 571 WGGPG-GYVYQKAYLEFFC------SKDKLDTLVEKSKAF-------------------- 473
WG PG G+V+QKA++EFFC +K K L S+ F
Sbjct: 532 WGPPGEGFVFQKAFVEFFCPSSDYQNKVKPTLLKHGSEEFSWFAINAAGHLESSFLISTS 591
Query: 472 ----PSITYMAVNKSEKWVSSTGESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEAFE 305
P T AV +++ ES AVTWG F +E+ TI++ SF+ W +EAF
Sbjct: 592 SSPKPEDTSSAVAAADEEPLEIRESTGMAVTWGAFRGREITTPTIIEEVSFRAWGEEAFR 651
Query: 304 IWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNKYINGDI 179
IW W +YP + +LL E KN +L+ ++ ++Y G +
Sbjct: 652 IWD-EWRRIYPRGSATERLLNETKNDVWLLCVIGHRYGAGTV 692
[190][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 85.5 bits (210), Expect = 3e-15
Identities = 39/85 (45%), Positives = 55/85 (64%), Gaps = 1/85 (1%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSEKWVSSTGESDVNAV 395
WG GGYV+QKAYLEFF S++ + L++ K + + Y VN + +++ E NAV
Sbjct: 530 WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV 589
Query: 394 TWGVFPAKEVIQATIVDAASFKVWK 320
TWG+FP +E+IQ T+VD SF WK
Sbjct: 590 TWGIFPGREIIQPTVVDPVSFMFWK 614
[191][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 82.4 bits (202), Expect = 2e-14
Identities = 54/136 (39%), Positives = 74/136 (54%), Gaps = 10/136 (7%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSE-----KWVSS--TG 416
WG GYV+QKAYLEFF S + + L++ K + P + Y VN + K +SS TG
Sbjct: 494 WGPSRGYVFQKAYLEFFTSSEMVTALIKVLKRYEPRVNYHIVNVHKHTQLLKLLSSSDTG 553
Query: 415 ESDV--NAVTWGVFPAKEVIQATIVDAASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
V NA G VI +I D DEAF +W WA LY E+ PSR +++
Sbjct: 554 MGPVIQNAQDLGNL---SVIWISITD--------DEAFALWIEQWAKLYEEESPSRMIIQ 602
Query: 241 EVKNSYYLVSLVDNKY 194
+ ++YYLV+LVDN +
Sbjct: 603 YIHDNYYLVNLVDNDF 618
[192][TOP]
>UniRef100_B6QFH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QFH8_PENMQ
Length = 710
Score = 82.4 bits (202), Expect = 2e-14
Identities = 51/159 (32%), Positives = 76/159 (47%), Gaps = 33/159 (20%)
Frame = -1
Query: 571 WGGPG-GYVYQKAYLEFFC------SKDKLDTLVEKSKAFPSITYMAVNKSEKWVSS--- 422
WG PG G+V+QKA++EFFC +K K L S+ F ++ A+N + SS
Sbjct: 530 WGPPGEGFVFQKAFVEFFCPNADYQNKVKPTLLKHGSEEF---SWFAINATGHLESSFLL 586
Query: 421 -----------------------TGESDVNAVTWGVFPAKEVIQATIVDAASFKVWKDEA 311
ES AVTWG F +E+ TI++ SF+ W +EA
Sbjct: 587 SASSSPKPEDASSTIAADEEPVEVRESKGMAVTWGAFRGREITTPTIIEEVSFRAWGEEA 646
Query: 310 FEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNKY 194
F IW W +YP + +LL E KN +L+ ++ ++Y
Sbjct: 647 FRIWD-EWRRIYPRGSATERLLNETKNDAWLLCVIGHRY 684
[193][TOP]
>UniRef100_A7S359 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
RepID=A7S359_NEMVE
Length = 102
Score = 54.7 bits (130), Expect = 5e-06
Identities = 22/42 (52%), Positives = 30/42 (71%)
Frame = -1
Query: 571 WGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVN 446
WGG GGY+YQKAYLEFF S + + L+++ K +P + Y VN
Sbjct: 51 WGGEGGYIYQKAYLEFFASPEVVYILLQELKNYPQVNYHVVN 92