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[1][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 298 bits (762), Expect = 2e-79
Identities = 142/142 (100%), Positives = 142/142 (100%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE
Sbjct: 333 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 392
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS
Sbjct: 393 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 452
Query: 423 PTVGWGGPVGYVYQKAYLEFFC 488
PTVGWGGPVGYVYQKAYLEFFC
Sbjct: 453 PTVGWGGPVGYVYQKAYLEFFC 474
[2][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=B9DHL6_ARATH
Length = 402
Score = 264 bits (675), Expect = 2e-69
Identities = 120/142 (84%), Positives = 131/142 (92%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
ANRPKSYISRTKGW DFP GRWGDS SA+Y LSD+QF+RP+ RDKKLQQEWVVPLKS+E
Sbjct: 143 ANRPKSYISRTKGWNDFPHGRWGDSHSAAYSTLSDYQFARPKGRDKKLQQEWVVPLKSIE 202
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
D+QEKFKELC+GNLKSSPWSELDGLQPET+IINEQL K+NS GFLTINSQPSVNA +SDS
Sbjct: 203 DVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDS 262
Query: 423 PTVGWGGPVGYVYQKAYLEFFC 488
P +GWGGP GYVYQKAYLEFFC
Sbjct: 263 PAIGWGGPGGYVYQKAYLEFFC 284
[3][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 264 bits (675), Expect = 2e-69
Identities = 120/142 (84%), Positives = 131/142 (92%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
ANRPKSYISRTKGW DFP GRWGDS SA+Y LSD+QF+RP+ RDKKLQQEWVVPLKS+E
Sbjct: 333 ANRPKSYISRTKGWNDFPHGRWGDSHSAAYSTLSDYQFARPKGRDKKLQQEWVVPLKSIE 392
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
D+QEKFKELC+GNLKSSPWSELDGLQPET+IINEQL K+NS GFLTINSQPSVNA +SDS
Sbjct: 393 DVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDS 452
Query: 423 PTVGWGGPVGYVYQKAYLEFFC 488
P +GWGGP GYVYQKAYLEFFC
Sbjct: 453 PAIGWGGPGGYVYQKAYLEFFC 474
[4][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 249 bits (637), Expect = 5e-65
Identities = 116/142 (81%), Positives = 126/142 (88%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
ANRPKSYISRT GWE +PQGRWGDS + SYGALSDHQF RPRARDKKL EWVVPL S E
Sbjct: 348 ANRPKSYISRTLGWEQYPQGRWGDSCNPSYGALSDHQFMRPRARDKKLHDEWVVPLSSAE 407
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
DI EKFK+ CLG LK+SPWSELDGLQPET+IINEQL K+N KGFLTINSQP+VN E+SDS
Sbjct: 408 DIFEKFKKHCLGKLKTSPWSELDGLQPETKIINEQLGKINLKGFLTINSQPAVNGEKSDS 467
Query: 423 PTVGWGGPVGYVYQKAYLEFFC 488
P+VGWGGP GYVYQKAY+EFFC
Sbjct: 468 PSVGWGGPGGYVYQKAYIEFFC 489
[5][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 246 bits (627), Expect = 7e-64
Identities = 110/142 (77%), Positives = 127/142 (89%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
ANRPKSYISRT GW+ +P GRWGDSR+ SYGAL+DHQF+RPR R KKLQ+EW VPLKSV+
Sbjct: 321 ANRPKSYISRTTGWDQYPHGRWGDSRNPSYGALNDHQFTRPRGRGKKLQEEWAVPLKSVQ 380
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
DI E+F C G LKSSPWSELDGLQPET II++QL+K+NSKGFLTINSQP+VNAE+S+S
Sbjct: 381 DINERFVNFCEGKLKSSPWSELDGLQPETTIIDDQLVKINSKGFLTINSQPAVNAEKSES 440
Query: 423 PTVGWGGPVGYVYQKAYLEFFC 488
P+VGWGGP GYVYQKAY+EFFC
Sbjct: 441 PSVGWGGPGGYVYQKAYVEFFC 462
[6][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 245 bits (625), Expect = 1e-63
Identities = 109/142 (76%), Positives = 124/142 (87%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
ANRPKSY+ RT GW+ +P GRWGDSR+ SYGAL+DHQF+RPR R KKLQ+EW VPLKSVE
Sbjct: 333 ANRPKSYLKRTLGWDQYPHGRWGDSRNPSYGALTDHQFTRPRGRGKKLQEEWAVPLKSVE 392
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
DI E+F C G L SSPWSELDGLQPET+II++QL+K+N KGFLTINSQP+VN E+SDS
Sbjct: 393 DISERFTNFCQGKLTSSPWSELDGLQPETKIIDDQLVKINQKGFLTINSQPAVNGEKSDS 452
Query: 423 PTVGWGGPVGYVYQKAYLEFFC 488
PTVGWGGP GYVYQKAYLEFFC
Sbjct: 453 PTVGWGGPGGYVYQKAYLEFFC 474
[7][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 245 bits (625), Expect = 1e-63
Identities = 113/142 (79%), Positives = 125/142 (88%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
ANRPKSY++RT GW+ +P GRWGDSR+ SYGALSD+QF RPRAR KKL +EW PLKSVE
Sbjct: 344 ANRPKSYLTRTIGWDQYPHGRWGDSRNPSYGALSDYQFMRPRARGKKLLEEWAAPLKSVE 403
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
DI EKFK CLG LKSSPWSELDGLQPET+IINEQL K+N KGFLTINSQP+VN E+SDS
Sbjct: 404 DIYEKFKVYCLGKLKSSPWSELDGLQPETKIINEQLGKINLKGFLTINSQPAVNGEKSDS 463
Query: 423 PTVGWGGPVGYVYQKAYLEFFC 488
P+VGWGGP GYVYQKAYLEFFC
Sbjct: 464 PSVGWGGPGGYVYQKAYLEFFC 485
[8][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 243 bits (620), Expect = 5e-63
Identities = 108/142 (76%), Positives = 123/142 (86%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
ANRPKSY+ RT GW+ +P GRWGDSR+ SYGAL+DHQF+RPR R KKLQ+EW VPLKSVE
Sbjct: 333 ANRPKSYLKRTLGWDQYPHGRWGDSRNPSYGALTDHQFTRPRGRGKKLQEEWAVPLKSVE 392
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
DI E+F C G L SSPWSELDGLQPET+II++QL+ +N KGFLTINSQP+VN E+SDS
Sbjct: 393 DISERFTNFCQGKLTSSPWSELDGLQPETKIIDDQLVNINQKGFLTINSQPAVNGEKSDS 452
Query: 423 PTVGWGGPVGYVYQKAYLEFFC 488
PTVGWGGP GYVYQKAYLEFFC
Sbjct: 453 PTVGWGGPGGYVYQKAYLEFFC 474
[9][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 242 bits (617), Expect = 1e-62
Identities = 112/142 (78%), Positives = 125/142 (88%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
ANRPKSY+SRT GW+ +P GRWGDS + SYGALSD+QF RPRAR KKL +EW PLKSVE
Sbjct: 347 ANRPKSYLSRTIGWDQYPHGRWGDSHNPSYGALSDYQFMRPRARGKKLFEEWASPLKSVE 406
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
DI EKFK CLG LKSSPWSEL+GLQPET+IINEQL ++N KGFLTINSQP+VNAE+SDS
Sbjct: 407 DIYEKFKVYCLGKLKSSPWSELEGLQPETKIINEQLGRINLKGFLTINSQPAVNAEKSDS 466
Query: 423 PTVGWGGPVGYVYQKAYLEFFC 488
P+VGWGGP GYVYQKAYLEFFC
Sbjct: 467 PSVGWGGPGGYVYQKAYLEFFC 488
[10][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 240 bits (613), Expect = 3e-62
Identities = 108/142 (76%), Positives = 124/142 (87%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
ANRPKSYISRT GW+ +P GRWGDSR+ SYGAL+D+QF+RPR R KKLQ+EW VP+KSVE
Sbjct: 333 ANRPKSYISRTLGWDQYPHGRWGDSRNPSYGALTDYQFTRPRGRGKKLQEEWAVPVKSVE 392
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
DI E+F C G L SSPWSELDGLQPET+II++QL+K+N KGFLTINSQP+VN ERSDS
Sbjct: 393 DINERFMNFCQGKLTSSPWSELDGLQPETKIIDDQLVKINQKGFLTINSQPAVNGERSDS 452
Query: 423 PTVGWGGPVGYVYQKAYLEFFC 488
+VGWGGP GYVYQKAYLEFFC
Sbjct: 453 TSVGWGGPGGYVYQKAYLEFFC 474
[11][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 240 bits (613), Expect = 3e-62
Identities = 108/142 (76%), Positives = 124/142 (87%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
ANRPKSYISRT GW+ +P GRWGDSR+ SYGAL+D+QF+RPR R KKLQ+EW VP+KSVE
Sbjct: 333 ANRPKSYISRTLGWDQYPHGRWGDSRNPSYGALTDYQFTRPRGRGKKLQEEWAVPVKSVE 392
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
DI E+F C G L SSPWSELDGLQPET+II++QL+K+N KGFLTINSQP+VN ERSDS
Sbjct: 393 DINERFMNFCQGKLTSSPWSELDGLQPETKIIDDQLVKINQKGFLTINSQPAVNGERSDS 452
Query: 423 PTVGWGGPVGYVYQKAYLEFFC 488
+VGWGGP GYVYQKAYLEFFC
Sbjct: 453 TSVGWGGPGGYVYQKAYLEFFC 474
[12][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 236 bits (603), Expect = 4e-61
Identities = 108/142 (76%), Positives = 124/142 (87%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
ANRP+SYISRT GW+ +P GRW DS + SYG L+D+QF RPRARDKKLQ EWVVPLKS+E
Sbjct: 333 ANRPRSYISRTIGWDQYPHGRWSDSCNPSYGGLTDYQFMRPRARDKKLQDEWVVPLKSIE 392
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
D+QE+F + CLG LKSSPWSELDGLQPE++IINE L +NSKGFLTINSQP+VN E+SDS
Sbjct: 393 DVQERFIKFCLGKLKSSPWSELDGLQPESKIINELLGNINSKGFLTINSQPAVNGEKSDS 452
Query: 423 PTVGWGGPVGYVYQKAYLEFFC 488
+VGWGGP GYVYQKAYLEFFC
Sbjct: 453 LSVGWGGPGGYVYQKAYLEFFC 474
[13][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 236 bits (603), Expect = 4e-61
Identities = 108/142 (76%), Positives = 124/142 (87%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
ANRP+SYISRT GW+ +P GRW DS + SYG L+D+QF RPRARDKKLQ EWVVPLKS+E
Sbjct: 326 ANRPRSYISRTIGWDQYPHGRWSDSCNPSYGGLTDYQFMRPRARDKKLQDEWVVPLKSIE 385
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
D+QE+F + CLG LKSSPWSELDGLQPE++IINE L +NSKGFLTINSQP+VN E+SDS
Sbjct: 386 DVQERFIKFCLGKLKSSPWSELDGLQPESKIINELLGNINSKGFLTINSQPAVNGEKSDS 445
Query: 423 PTVGWGGPVGYVYQKAYLEFFC 488
+VGWGGP GYVYQKAYLEFFC
Sbjct: 446 LSVGWGGPGGYVYQKAYLEFFC 467
[14][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 236 bits (603), Expect = 4e-61
Identities = 108/142 (76%), Positives = 124/142 (87%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
ANRP+SYISRT GW+ +P GRW DS + SYG L+D+QF RPRARDKKLQ EWVVPLKS+E
Sbjct: 333 ANRPRSYISRTIGWDQYPHGRWSDSCNPSYGGLTDYQFMRPRARDKKLQDEWVVPLKSIE 392
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
D+QE+F + CLG LKSSPWSELDGLQPE++IINE L +NSKGFLTINSQP+VN E+SDS
Sbjct: 393 DVQERFIKFCLGKLKSSPWSELDGLQPESKIINELLGNINSKGFLTINSQPAVNGEKSDS 452
Query: 423 PTVGWGGPVGYVYQKAYLEFFC 488
+VGWGGP GYVYQKAYLEFFC
Sbjct: 453 LSVGWGGPGGYVYQKAYLEFFC 474
[15][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 226 bits (576), Expect = 6e-58
Identities = 102/142 (71%), Positives = 121/142 (85%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
ANRP+SYISRT GWE FP GRWGD+RS +YGAL+D+QF R R+R KK+ +EWVVPL S+
Sbjct: 333 ANRPRSYISRTIGWEQFPNGRWGDARSPAYGALNDYQFLRRRSRSKKILEEWVVPLSSIV 392
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
DIQEKF C+G LKS+PWSELDGLQPET INE+L ++N KGFLTINSQP+VN E+SDS
Sbjct: 393 DIQEKFANFCVGKLKSNPWSELDGLQPETVKINEKLEQLNRKGFLTINSQPAVNGEKSDS 452
Query: 423 PTVGWGGPVGYVYQKAYLEFFC 488
P++GWGG GYVYQKAY+EFFC
Sbjct: 453 PSIGWGGAAGYVYQKAYVEFFC 474
[16][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 213 bits (542), Expect = 5e-54
Identities = 94/142 (66%), Positives = 115/142 (80%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
ANRP+SYISRT W+DFP+GRWGD+ + +YG+ SDHQF+R + R KKLQ+EW VPL S E
Sbjct: 333 ANRPRSYISRTTSWDDFPRGRWGDTANPAYGSFSDHQFTRKKTRSKKLQKEWAVPLNSSE 392
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
D+ F + C G L + PWSEL+GLQPET INE+L+ +N GFLTINSQP+VN E+SDS
Sbjct: 393 DVNAIFAKYCQGTLSTHPWSELEGLQPETVQINEKLVALNQGGFLTINSQPAVNGEKSDS 452
Query: 423 PTVGWGGPVGYVYQKAYLEFFC 488
P+VGWGGP GYVYQKAY+EFFC
Sbjct: 453 PSVGWGGPGGYVYQKAYVEFFC 474
[17][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 213 bits (541), Expect = 7e-54
Identities = 92/142 (64%), Positives = 117/142 (82%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
ANRP+SYISRT W++FP+GRWGD+ + +YG+ SDHQF R + R KKLQ+EW VPL S E
Sbjct: 333 ANRPRSYISRTTSWDEFPRGRWGDTGNPAYGSFSDHQFLRKKTRSKKLQKEWAVPLNSCE 392
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
D+ + F + C G L + PWSEL+GLQPET IN++L+ +N++GFLTINSQP+VN E+SDS
Sbjct: 393 DVNQIFAKYCQGTLSTHPWSELEGLQPETSQINDKLVALNTQGFLTINSQPAVNGEKSDS 452
Query: 423 PTVGWGGPVGYVYQKAYLEFFC 488
P+VGWGGP GYVYQKAY+EFFC
Sbjct: 453 PSVGWGGPGGYVYQKAYVEFFC 474
[18][TOP]
>UniRef100_A6N158 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Oryza sativa
Indica Group RepID=A6N158_ORYSI
Length = 237
Score = 194 bits (492), Expect = 3e-48
Identities = 88/117 (75%), Positives = 102/117 (87%)
Frame = +3
Query: 138 RSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFKELCLGNLKSSPWSELDGL 317
R+ SYGAL+D+QF+RPR R KKLQ+EW VP+KSVEDI E+F C G L SSPWSELDGL
Sbjct: 1 RNPSYGALTDYQFTRPRGRGKKLQEEWAVPVKSVEDINERFMNFCQGKLTSSPWSELDGL 60
Query: 318 QPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFC 488
QPET+II++QL+K+N KGFLTINSQP+VN ERSDS +VGWGGP GYVYQKAYLEFFC
Sbjct: 61 QPETKIIDDQLVKINQKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFC 117
[19][TOP]
>UniRef100_A9P8D1 Putative uncharacterized protein n=1 Tax=Populus trichocarpa
RepID=A9P8D1_POPTR
Length = 224
Score = 181 bits (458), Expect = 3e-44
Identities = 85/103 (82%), Positives = 91/103 (88%)
Frame = +3
Query: 180 RPRARDKKLQQEWVVPLKSVEDIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKV 359
RPRAR KKL +EW PLKSVEDI EKFK CLG LKSSPWSELDGLQPET+IINEQL K+
Sbjct: 2 RPRARGKKLLEEWAAPLKSVEDIYEKFKVYCLGKLKSSPWSELDGLQPETKIINEQLGKI 61
Query: 360 NSKGFLTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFC 488
N KGFLTINSQP+VN E+SDSP+VGWGGP GYVYQKAYLEFFC
Sbjct: 62 NLKGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYLEFFC 104
[20][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 153 bits (386), Expect = 6e-36
Identities = 74/147 (50%), Positives = 96/147 (65%), Gaps = 5/147 (3%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPR----ARDKKLQQEWVVPL 230
+NRPK+Y+ RT+ W+ +P GRWG++RS +YGALSDHQF R AR +K + W
Sbjct: 329 SNRPKAYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHSTGEARREKARAAWGAAP 388
Query: 231 KSVEDIQEKFKELCLGNLKSSPWSELDG-LQPETRIINEQLIKVNSKGFLTINSQPSVNA 407
SV+D+++ F + G + PW+ELDG L E I E L +N+ G+LTINSQP VN
Sbjct: 389 ASVDDVKQVFVKYIKGEVSLLPWAELDGGLTAEAAAIREPLAALNANGYLTINSQPRVNG 448
Query: 408 ERSDSPTVGWGGPVGYVYQKAYLEFFC 488
SD GWGGP GYVY KAY+EFFC
Sbjct: 449 VASDDAVHGWGGPGGYVYGKAYVEFFC 475
[21][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 138 bits (348), Expect = 2e-31
Identities = 68/150 (45%), Positives = 97/150 (64%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSY+ RT+ W++FP GRWG S S ++G L+D+ + +P A+ ++L W L
Sbjct: 357 ASRPKSYVYRTQEWDEFPNGRWGSSESPAFGELNDYYLFYLKPNAKKEELLDMWGHELTC 416
Query: 237 VEDIQEKFKELCLGN-------LKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
++D+ + F G ++ PW++ D L ET IN++L ++NS+G LTINSQP
Sbjct: 417 LQDVCDVFTNYITGKESKNGKKVRKIPWND-DDLAAETSFINDKLARINSRGVLTINSQP 475
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
+VNA S P VGWG P GYV+QKAYLEFF
Sbjct: 476 NVNAAPSTDPVVGWGTPGGYVFQKAYLEFF 505
[22][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 137 bits (346), Expect = 3e-31
Identities = 67/141 (47%), Positives = 97/141 (68%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
ANR KSY++RT+ W++FP GRWGD+RS +YG + D + R +++ ++ W P ++
Sbjct: 343 ANRAKSYVNRTETWDEFPNGRWGDARSPAYGDV-DAYGVKLRYSNEEAKEMWGAPT-CLD 400
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
D++ F++ C G +K+ PWSE + ET +I+++L K+N GFLTINSQP+V+ RSD
Sbjct: 401 DVKTLFQQFCAGQVKALPWSETP-VARETSVISDKLAKMNQLGFLTINSQPAVDGARSDD 459
Query: 423 PTVGWGGPVGYVYQKAYLEFF 485
GWG GYVYQKAYLEFF
Sbjct: 460 KVHGWGPKNGYVYQKAYLEFF 480
[23][TOP]
>UniRef100_A8Q9P3 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8Q9P3_MALGO
Length = 515
Score = 136 bits (342), Expect = 8e-31
Identities = 72/143 (50%), Positives = 87/143 (60%), Gaps = 2/143 (1%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQ--QEWVVPLKS 236
ANR KSYI RT W++FP GRWGD+RS +YG D P R K + W P +
Sbjct: 252 ANRAKSYIDRTDAWDEFPNGRWGDARSPAYG---DADVFGPYLRQTKEEALDLWGSPT-T 307
Query: 237 VEDIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERS 416
++D+Q F C G L PWS+ L ET +INE L +N +GF TINSQP+V+ RS
Sbjct: 308 IQDLQSLFARFCTGELACLPWSDAP-LAKETSVINEPLRALNERGFFTINSQPAVDGARS 366
Query: 417 DSPTVGWGGPVGYVYQKAYLEFF 485
D P GWG GYVYQKAYLEFF
Sbjct: 367 DDPVHGWGPKHGYVYQKAYLEFF 389
[24][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 135 bits (341), Expect = 1e-30
Identities = 70/149 (46%), Positives = 90/149 (60%), Gaps = 9/149 (6%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKSV 239
+RPKSYI RT+GW++FP GRWGDS S ++G L D+ F R R KL+ W L S
Sbjct: 342 DRPKSYIHRTQGWDEFPNGRWGDSASPAFGELKDYHLFFLRSRTAKDKLRSLWGKELTSE 401
Query: 240 EDIQEKFKELCLG-------NLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPS 398
D+ + FK G + +PW++ DGL PET +++ L + N G LTINSQP+
Sbjct: 402 ADVWKVFKHFITGAVNENGVKVTETPWND-DGLSPETNVLSSTLSRYNELGVLTINSQPN 460
Query: 399 VNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
VNA S P GWG GY+ QKAYLEFF
Sbjct: 461 VNAVPSTHPIYGWGDKGGYISQKAYLEFF 489
[25][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 134 bits (336), Expect = 4e-30
Identities = 69/141 (48%), Positives = 91/141 (64%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
ANR KSYISRT+ W+++P GR+GDSRS +YG + + + + ++ L+ W P ++E
Sbjct: 287 ANRTKSYISRTENWDEYPNGRFGDSRSPAYGEIDGYGTAIKQTKENALKL-WGYPT-TLE 344
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
++ F + C G L + PWS+ ET II QL K+N GFLTINSQP+VN RSD
Sbjct: 345 EVSVLFAKFCKGELDALPWSD-SAPSKETSIIATQLAKMNELGFLTINSQPAVNGARSDD 403
Query: 423 PTVGWGGPVGYVYQKAYLEFF 485
GWG GYVYQKAYLEFF
Sbjct: 404 KIFGWGPSNGYVYQKAYLEFF 424
[26][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 133 bits (334), Expect = 7e-30
Identities = 69/150 (46%), Positives = 94/150 (62%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSY+ RT W++FP GRWG+S + ++ SDH + R +A+ +++ + W L
Sbjct: 313 ASRPKSYLYRTSDWDEFPNGRWGNSSAPAFRDFSDHHLFYLRSKAKKEQMLKMWGQQLND 372
Query: 237 VEDIQEKFKELCLGN-------LKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
V+D+ E FK G + S PW++ + L ET I E+LI NS G L+INSQP
Sbjct: 373 VQDVFEVFKCYISGEKNENGVKVTSLPWND-EELALETSFIKEKLIHFNSNGILSINSQP 431
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
SVNA S P +GWGG GY+YQKAYLEFF
Sbjct: 432 SVNAASSTDPLLGWGGEGGYIYQKAYLEFF 461
[27][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 132 bits (332), Expect = 1e-29
Identities = 69/150 (46%), Positives = 92/150 (61%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKK--LQQEWVVPLKS 236
A+RPKSYI RT+ W+DFP GRWG+S S ++G L+D+ +++ K L Q W L S
Sbjct: 368 ASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQMWGEELMS 427
Query: 237 VEDIQEKFKELCLGNLKSS-------PWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + E F G S PW++ D L PET ++ ++L KVN +G LTINSQP
Sbjct: 428 EESVYEVFTNYITGQTNRSGHKVMCLPWND-DPLAPETNLLKDELEKVNRRGVLTINSQP 486
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
++N + S VGWG GYV+QKAYLEFF
Sbjct: 487 NINGKASSDAIVGWGPAGGYVFQKAYLEFF 516
[28][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 131 bits (330), Expect = 2e-29
Identities = 72/145 (49%), Positives = 90/145 (62%), Gaps = 3/145 (2%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSD--HQFSRPR-ARDKKLQQEWVVPLK 233
ANRPKSY+ RT+ W++FP GRWGDS S ++G LS+ H +S + D + P K
Sbjct: 362 ANRPKSYVLRTEDWDEFPNGRWGDSTSPAFGELSNFSHYYSFSLGSEDDQRNMLGSNPTK 421
Query: 234 SVEDIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAER 413
S ED+ E F G + PW E LQPE+ +I +L +N GFLTINSQPSVNA
Sbjct: 422 S-EDVYEVFALYIEGKIPHIPWCEAT-LQPESFLIQTKLAALNRAGFLTINSQPSVNAAL 479
Query: 414 SDSPTVGWGGPVGYVYQKAYLEFFC 488
S + GWGGP GY+YQKAY E FC
Sbjct: 480 STHESFGWGGPGGYIYQKAYCECFC 504
[29][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 131 bits (329), Expect = 3e-29
Identities = 66/150 (44%), Positives = 94/150 (62%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
++RPKSYI RT W++FP GRWG+S + S+ LSDH + + + +++ + W L
Sbjct: 346 SSRPKSYIHRTSNWDEFPNGRWGNSSAPSFAELSDHHLFYLKSKESEEERLKMWGEKLDC 405
Query: 237 VEDIQEKFKELCLGN-------LKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
+ED+ F+ G +KS P ++ D LQPET ++++QL ++N GFLT NSQP
Sbjct: 406 IEDVYHVFQCYLSGKKNKWGYKVKSLPLND-DELQPETSLLSDQLYRINGHGFLTTNSQP 464
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
+VNA S GWGG GY+YQKAYLEFF
Sbjct: 465 AVNAALSTDERFGWGGAGGYIYQKAYLEFF 494
[30][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 130 bits (328), Expect = 3e-29
Identities = 72/141 (51%), Positives = 87/141 (61%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
ANR KSYISRT+ W+++P GR+GDSRS +YG L + + L+ W P S
Sbjct: 327 ANRTKSYISRTENWDEYPNGRFGDSRSPAYGELDGYGVWIKQTVKDALKL-WGHPT-SFA 384
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
DI F C L + PWS+ Q ET +I EQL +N GFLTINSQP+VN+ RSD
Sbjct: 385 DIASLFSRFCTKKLSALPWSDQAPSQ-ETSVIAEQLATMNEFGFLTINSQPAVNSARSDD 443
Query: 423 PTVGWGGPVGYVYQKAYLEFF 485
P GWG GYVYQKAYLEFF
Sbjct: 444 PVFGWGPSNGYVYQKAYLEFF 464
[31][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 130 bits (326), Expect = 6e-29
Identities = 71/156 (45%), Positives = 95/156 (60%), Gaps = 15/156 (9%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKK--LQQEWVVPLKS 236
++RPKSYI RT+ W+DFP GRWG+S S ++G L+D+ +++ K L Q W L S
Sbjct: 372 SSRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALLQMWGEELLS 431
Query: 237 VEDIQEKF-------------KELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFL 377
E + E F K LCL PW++ + L PET ++ ++L KVN +G L
Sbjct: 432 EESVFEVFTCYITAQTNRSGQKVLCL------PWND-EPLAPETNLLKDELEKVNRRGVL 484
Query: 378 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
TINSQP++N + S P VGWG GYVYQKAYLEFF
Sbjct: 485 TINSQPNINGKPSTDPIVGWGPAGGYVYQKAYLEFF 520
[32][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 130 bits (326), Expect = 6e-29
Identities = 71/156 (45%), Positives = 95/156 (60%), Gaps = 15/156 (9%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKK--LQQEWVVPLKS 236
++RPKSYI RT+ W+DFP GRWG+S S ++G L+D+ +++ K L Q W L S
Sbjct: 372 SSRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALLQMWGEELLS 431
Query: 237 VEDIQEKF-------------KELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFL 377
E + E F K LCL PW++ + L PET ++ ++L KVN +G L
Sbjct: 432 EESVFEVFTCYITAQTNRSGQKVLCL------PWND-EPLAPETNLLKDELEKVNRRGVL 484
Query: 378 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
TINSQP++N + S P VGWG GYVYQKAYLEFF
Sbjct: 485 TINSQPNINGKPSTDPIVGWGPAGGYVYQKAYLEFF 520
[33][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 129 bits (325), Expect = 8e-29
Identities = 72/150 (48%), Positives = 89/150 (59%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKK--LQQEWVVPLKS 236
A+RPKSY+ RT W+++P GRWG S S ++G L D+ + KK L + W L+S
Sbjct: 352 ASRPKSYVHRTMMWDEYPNGRWGSSASPAFGELKDYHIFYLKNTSKKDELLKMWGEKLES 411
Query: 237 VEDIQEKFKELCLGN-------LKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
VED+ E F G + + PWS D L ET I + L +NSKG LTINSQP
Sbjct: 412 VEDVYEIFTCFVSGERNKYGYKVDALPWSN-DALALETLFIKKSLEYINSKGILTINSQP 470
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
+VNA S GWGGP GYVYQKAYLEFF
Sbjct: 471 NVNALPSTHEVFGWGGPNGYVYQKAYLEFF 500
[34][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 129 bits (324), Expect = 1e-28
Identities = 74/148 (50%), Positives = 88/148 (59%), Gaps = 7/148 (4%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFS----RPRARDKKLQQEWVVPL 230
ANR +SY+SRT W++FP GRWGDSRS +YG L + S P A + W P
Sbjct: 331 ANRTRSYLSRTADWDEFPNGRWGDSRSPAYGDLDGYPVSIGITAPDAYNL-----WGHPT 385
Query: 231 KSVEDIQEKFKELCLGNLKSSPWSELDGLQP---ETRIINEQLIKVNSKGFLTINSQPSV 401
S D+ F C G+L PWS QP ET +I EQL K+N G+LTINSQP+V
Sbjct: 386 TS-SDLHALFARFCRGDLAKLPWST----QPPASETSLIIEQLAKMNELGYLTINSQPAV 440
Query: 402 NAERSDSPTVGWGGPVGYVYQKAYLEFF 485
+ RSD GWG P GYVYQKAYLEFF
Sbjct: 441 DGVRSDDKVHGWGPPGGYVYQKAYLEFF 468
[35][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 129 bits (323), Expect = 1e-28
Identities = 67/150 (44%), Positives = 93/150 (62%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSYI RT+ W++FP GRWG+S S ++G L D+ + + ++ ++L + W L S
Sbjct: 362 ASRPKSYIHRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGQELNS 421
Query: 237 VEDIQEKFKELCLGN-------LKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + E F G + PW++ D L PET ++ +L KVN +G LTINSQP
Sbjct: 422 EESVFEVFTYYISGEPNPNGHKVNCLPWND-DPLAPETNLLKNELQKVNKRGILTINSQP 480
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
+VN + S P VGWG GYV+QKAYLEFF
Sbjct: 481 NVNGKPSTDPIVGWGPSRGYVFQKAYLEFF 510
[36][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 128 bits (322), Expect = 2e-28
Identities = 67/150 (44%), Positives = 93/150 (62%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSYI RT+ W++FP GRWG+S S ++G L D+ + + ++ ++L + W L S
Sbjct: 362 ASRPKSYIHRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGQELSS 421
Query: 237 VEDIQEKFKELCLGNLKSS-------PWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + E F G + PW++ D L PET ++ +L KVN +G LTINSQP
Sbjct: 422 EESVFEVFTYYISGEPNPNGHKVTCLPWND-DPLAPETNLLKSELQKVNKRGILTINSQP 480
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
+VN + S P VGWG GYV+QKAYLEFF
Sbjct: 481 NVNGKPSTDPIVGWGPSRGYVFQKAYLEFF 510
[37][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 128 bits (322), Expect = 2e-28
Identities = 67/150 (44%), Positives = 93/150 (62%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSYI RT+ W++FP GRWG+S S ++G L D+ + + ++ ++L + W L S
Sbjct: 362 ASRPKSYIHRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGQELSS 421
Query: 237 VEDIQEKFKELCLGNLKSS-------PWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + E F G + PW++ D L PET ++ +L KVN +G LTINSQP
Sbjct: 422 EESVFEVFTYYISGEPNPNGHKVTCLPWND-DPLAPETNLLKSELQKVNKRGILTINSQP 480
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
+VN + S P VGWG GYV+QKAYLEFF
Sbjct: 481 NVNGKPSTDPIVGWGPSRGYVFQKAYLEFF 510
[38][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 128 bits (322), Expect = 2e-28
Identities = 64/138 (46%), Positives = 87/138 (63%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR +SY++RT+ W++FP GRWGDSRS ++G L + ++ ++ W PL S++D
Sbjct: 327 NRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDSYGIGLKGTNEQNIKL-WGTPL-SIKD 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ + F G L+S PWSE + E I LI +N +GFLTINSQP+VN +S P
Sbjct: 385 LSDLFVRYMEGKLESLPWSE-QPITGEATSIRNDLIDLNRRGFLTINSQPAVNGAKSSDP 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
T GWG GYVYQKAYLE
Sbjct: 444 TFGWGPRNGYVYQKAYLE 461
[39][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 128 bits (321), Expect = 2e-28
Identities = 65/150 (43%), Positives = 95/150 (63%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSYI RT+GW++FP GRWG+S S ++G L D+ + + ++ ++L + W L S
Sbjct: 373 ASRPKSYIYRTQGWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTS 432
Query: 237 VEDIQEKFKELCLGN-------LKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + E F+ G + PW++ + L ET ++ E+L++VN G LTINSQP
Sbjct: 433 EESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINSQP 491
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
++N + S P VGWG GYV+QKAYLEFF
Sbjct: 492 NINGKPSSDPVVGWGPSGGYVFQKAYLEFF 521
[40][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 128 bits (321), Expect = 2e-28
Identities = 65/150 (43%), Positives = 95/150 (63%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSYI RT+GW++FP GRWG+S S ++G L D+ + + ++ ++L + W L S
Sbjct: 408 ASRPKSYIYRTQGWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTS 467
Query: 237 VEDIQEKFKELCLGN-------LKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + E F+ G + PW++ + L ET ++ E+L++VN G LTINSQP
Sbjct: 468 EESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINSQP 526
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
++N + S P VGWG GYV+QKAYLEFF
Sbjct: 527 NINGKPSSDPVVGWGPSGGYVFQKAYLEFF 556
[41][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
RepID=A8PV87_BRUMA
Length = 656
Score = 128 bits (321), Expect = 2e-28
Identities = 68/150 (45%), Positives = 94/150 (62%), Gaps = 11/150 (7%)
Frame = +3
Query: 69 RPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRA---RDKKLQQEWVVPLKSV 239
RPKSY+ RT+ W++FP GRWG+S S ++ L D+ + RD++L+ + L+++
Sbjct: 383 RPKSYVFRTREWDEFPNGRWGNSSSPAFNDLKDYYLFYLKGQPTRDEQLRM-YGERLETL 441
Query: 240 EDIQEKFKELCLGNLKSS-------PWSEL-DGLQPETRIINEQLIKVNSKGFLTINSQP 395
DIQ+ F N+ + PW+E DG++ ET +I +QL+ NS GFLTINSQP
Sbjct: 442 ADIQKVFVNFITQNINENGVKVSQLPWNEQHDGIRAETSLIKDQLLWCNSNGFLTINSQP 501
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
S+N S P VGWG P GY YQKAYLEFF
Sbjct: 502 SINGAPSTDPFVGWGKPGGYCYQKAYLEFF 531
[42][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 127 bits (318), Expect = 5e-28
Identities = 65/150 (43%), Positives = 95/150 (63%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSYI RT+ W++FP GRWG+S S ++G L D+ + + ++ ++L + W L S
Sbjct: 408 ASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTS 467
Query: 237 VEDIQEKFKELCLGN-------LKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + E F+ G + PW++ + L ET ++ E+L++VN G LTINSQP
Sbjct: 468 EESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINSQP 526
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
++NA+ S P VGWG GYV+QKAYLEFF
Sbjct: 527 NINAKPSSDPVVGWGPSGGYVFQKAYLEFF 556
[43][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 127 bits (318), Expect = 5e-28
Identities = 65/150 (43%), Positives = 95/150 (63%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSYI RT+ W++FP GRWG+S S ++G L D+ + + ++ ++L + W L S
Sbjct: 408 ASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTS 467
Query: 237 VEDIQEKFKELCLGN-------LKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + E F+ G + PW++ + L ET ++ E+L++VN G LTINSQP
Sbjct: 468 EESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINSQP 526
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
++NA+ S P VGWG GYV+QKAYLEFF
Sbjct: 527 NINAKPSSDPVVGWGPSGGYVFQKAYLEFF 556
[44][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 127 bits (318), Expect = 5e-28
Identities = 65/150 (43%), Positives = 95/150 (63%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSYI RT+ W++FP GRWG+S S ++G L D+ + + ++ ++L + W L S
Sbjct: 408 ASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTS 467
Query: 237 VEDIQEKFKELCLGN-------LKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + E F+ G + PW++ + L ET ++ E+L++VN G LTINSQP
Sbjct: 468 EESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINSQP 526
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
++NA+ S P VGWG GYV+QKAYLEFF
Sbjct: 527 NINAKPSSDPVVGWGPSGGYVFQKAYLEFF 556
[45][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 127 bits (318), Expect = 5e-28
Identities = 64/138 (46%), Positives = 88/138 (63%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR KSY++RT+ W++FP GRWGDSRS ++G L + + ++ ++ W P KS++D
Sbjct: 327 NRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDAYGIGLKGSNEQNIKL-WGQP-KSIKD 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
I E F ++S PWSE + E II LI++N +GFLTINSQP+V+ +S P
Sbjct: 385 IAELFVSYLENGIESLPWSEAP-ISSEADIIKSDLIELNRRGFLTINSQPAVDGVKSSDP 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG GYVYQKAYLE
Sbjct: 444 VYGWGPTNGYVYQKAYLE 461
[46][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 127 bits (318), Expect = 5e-28
Identities = 65/150 (43%), Positives = 95/150 (63%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSYI RT+ W++FP GRWG+S S ++G L D+ + + ++ ++L + W L S
Sbjct: 367 ASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTS 426
Query: 237 VEDIQEKFKELCLGN-------LKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + E F+ G + PW++ + L ET ++ E+L++VN G LTINSQP
Sbjct: 427 EESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINSQP 485
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
++NA+ S P VGWG GYV+QKAYLEFF
Sbjct: 486 NINAKPSSDPVVGWGPSGGYVFQKAYLEFF 515
[47][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
RepID=UPI0000E814FF
Length = 508
Score = 126 bits (316), Expect = 8e-28
Identities = 69/152 (45%), Positives = 91/152 (59%), Gaps = 11/152 (7%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQF----SRPRARDKKLQQEWVVPL 230
A+RPKSYI RT+ W+DFP GRWG+S S ++G L D+ S+P R++ L+ W L
Sbjct: 226 ASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKPSPREELLKM-WGEEL 284
Query: 231 KSVEDIQEKFKELCLGNLKSS-------PWSELDGLQPETRIINEQLIKVNSKGFLTINS 389
E + E F G + PW++ D L ET ++ EQL KVN +G LTINS
Sbjct: 285 TGEESVFEVFTCYITGEPNKNGHRVTCMPWND-DPLATETSLLKEQLEKVNRRGILTINS 343
Query: 390 QPSVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
QP++N + S P GWG GYV+QKAYLEFF
Sbjct: 344 QPNINGKPSTDPIFGWGPSGGYVFQKAYLEFF 375
[48][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 125 bits (315), Expect = 1e-27
Identities = 66/150 (44%), Positives = 92/150 (61%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSYI RT+ W+DFP GRWG+S S ++G L D+ + + ++ ++L + W L
Sbjct: 370 ASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTG 429
Query: 237 VEDIQEKFKELCLGNLKSS-------PWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + E F G + PW++ D L ET ++ +QL KVN +G LTINSQP
Sbjct: 430 EESVFEVFTCYITGEPNKNGYKVTCMPWND-DPLATETNLLKDQLEKVNRRGILTINSQP 488
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
++N + S P VGWG GYV+QKAYLEFF
Sbjct: 489 NINGKPSTDPIVGWGPSGGYVFQKAYLEFF 518
[49][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S5W8_NEMVE
Length = 619
Score = 125 bits (315), Expect = 1e-27
Identities = 71/150 (47%), Positives = 90/150 (60%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSD-HQFSRPRAR-DKKLQQEWVVPLKS 236
A+RP+SY+ RT WED P GRWG+S SAS+G L D H F +R D +L W L S
Sbjct: 342 ASRPRSYLIRTSNWEDMPNGRWGNSSSASFGDLKDYHLFLTGTSRKDSELLSMWGRELNS 401
Query: 237 VEDIQEKFKELCLGN-------LKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
+D+ + F G + PWS+ + L PET + E+L+ N G LTINSQP
Sbjct: 402 EQDVFDIFVCYLTGRDNKQGFKVTELPWSDGE-LAPETIPLVEKLVHANQNGILTINSQP 460
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
S+NA S+ P GWG P GYV+QKAYLEFF
Sbjct: 461 SLNAVPSEDPNHGWGKPGGYVFQKAYLEFF 490
[50][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 125 bits (314), Expect = 1e-27
Identities = 64/150 (42%), Positives = 93/150 (62%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A RPKSYI RT+ W++FP GRWG+S S ++G L D+ + + ++ ++L + W L S
Sbjct: 367 ATRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTS 426
Query: 237 VEDIQEKFKELCLGNLKSS-------PWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + E F G + PW++ + L ET ++ E+L++VN +G LTINSQP
Sbjct: 427 EESVFEVFAHYLSGEPNQNGYKVTCLPWND-EPLAAETSLMKEELLRVNRQGVLTINSQP 485
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
++N + S P VGWG GYV+QKAYLEFF
Sbjct: 486 NINGKPSSDPVVGWGPSGGYVFQKAYLEFF 515
[51][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 125 bits (314), Expect = 1e-27
Identities = 64/141 (45%), Positives = 85/141 (60%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR SYI+RT W++FP GRWGDSRS ++G + R KK W P ++++D
Sbjct: 331 NRKYSYITRTATWDEFPNGRWGDSRSPAFGDIDLCASELLRQSPKKAYDLWGTP-QTLKD 389
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ G LKS PWS+ + +T ++ E LI +N KGFLT+NSQP++NA +S
Sbjct: 390 FSDIIVSYLQGELKSLPWSD-GPIGEDTSVMVENLINLNHKGFLTMNSQPALNAVKSSEK 448
Query: 426 TVGWGGPVGYVYQKAYLEFFC 488
GWG GYVYQK YLEFFC
Sbjct: 449 VYGWGPKNGYVYQKQYLEFFC 469
[52][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Canis lupus familiaris RepID=UPI00005A03BF
Length = 780
Score = 125 bits (313), Expect = 2e-27
Identities = 64/150 (42%), Positives = 94/150 (62%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSYI RT+ W++FP GRWG+S S ++G L D+ + + ++ ++L + W L S
Sbjct: 493 ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTS 552
Query: 237 VEDIQEKFKELCLGN-------LKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + E F G + PW++ + L ET ++ E+L++VN +G LTINSQP
Sbjct: 553 EESVFEVFARYLSGEPNQHGYKVTCLPWND-EPLAAETSLMKEELLRVNRQGILTINSQP 611
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
++N + S P VGWG GYV+QKAYLEFF
Sbjct: 612 NINGKPSSDPIVGWGPSGGYVFQKAYLEFF 641
[53][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 125 bits (313), Expect = 2e-27
Identities = 64/150 (42%), Positives = 94/150 (62%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSYI RT+ W++FP GRWG+S S ++G L D+ + + ++ ++L + W L S
Sbjct: 409 ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTS 468
Query: 237 VEDIQEKFKELCLGN-------LKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + E F G + PW++ + L ET ++ E+L++VN +G LTINSQP
Sbjct: 469 EESVFEVFARYLSGEPNQHGYKVTCLPWND-EPLAAETSLMKEELLRVNRQGILTINSQP 527
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
++N + S P VGWG GYV+QKAYLEFF
Sbjct: 528 NINGKPSSDPIVGWGPSGGYVFQKAYLEFF 557
[54][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 125 bits (313), Expect = 2e-27
Identities = 63/150 (42%), Positives = 94/150 (62%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSYI RT+ W++FP GRWG+S S ++G L D+ + + ++ ++L + W L S
Sbjct: 367 ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTS 426
Query: 237 VEDIQEKFKELCLGNLKSS-------PWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + + F G + PW++ + L ET ++ E+L++VN +G LTINSQP
Sbjct: 427 EESVFQVFAHYLSGEPNQNGYKVTCLPWND-EPLAAETSLMKEELLRVNRRGILTINSQP 485
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
++N + S P VGWG GYV+QKAYLEFF
Sbjct: 486 NINGKPSSDPIVGWGPSGGYVFQKAYLEFF 515
[55][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 124 bits (312), Expect = 2e-27
Identities = 65/150 (43%), Positives = 92/150 (61%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKK--LQQEWVVPLKS 236
A+RPKSYI RT+ W++FP GRWG+S S ++G L D+ +++ + L + W L S
Sbjct: 362 ASRPKSYIYRTQAWDEFPNGRWGNSSSPAFGELKDYYLFCLKSKTPRTELLKMWGEELTS 421
Query: 237 VEDIQEKFKELCLGNLKSS-------PWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + E F G + PW++ + L ET ++ E+L+KVN +G LTINSQP
Sbjct: 422 EESVFEVFTYYLSGEPNQNGYKVTCLPWND-EPLAAETSLMKEELLKVNQRGILTINSQP 480
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
++N + S P VGWG GYV+QKAYLEFF
Sbjct: 481 NINGKPSTDPIVGWGPSGGYVFQKAYLEFF 510
[56][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 124 bits (312), Expect = 2e-27
Identities = 61/139 (43%), Positives = 85/139 (61%)
Frame = +3
Query: 69 RPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDI 248
R +SY+SRT W++ P GRWGDSRS ++G ++ R K++ W P KS +I
Sbjct: 331 RNESYVSRTDQWDELPHGRWGDSRSPAFGEFDAIRYGL-RMSPKEITTSWGSP-KSYSEI 388
Query: 249 QEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPT 428
+ F C + S PWS+L + E +I +QL+ +N FLTINSQP++N E+S P
Sbjct: 389 GDLFARYCEKKISSLPWSDLP-ISDEADLIRDQLLSMNRNAFLTINSQPALNGEKSSHPV 447
Query: 429 VGWGGPVGYVYQKAYLEFF 485
GWG P GYV+QK Y+EFF
Sbjct: 448 FGWGPPNGYVFQKPYVEFF 466
[57][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 124 bits (311), Expect = 3e-27
Identities = 64/150 (42%), Positives = 94/150 (62%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSYI RT+ W++FP GRWG+S S ++G L D+ + + ++ ++L + W L S
Sbjct: 391 ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTS 450
Query: 237 VEDIQEKFKELCLGNLKSS-------PWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + E F G + PW++ + L ET ++ E+L++VN +G LTINSQP
Sbjct: 451 EESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINSQP 509
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
++N + S P VGWG GYV+QKAYLEFF
Sbjct: 510 NINGKPSSDPIVGWGPSGGYVFQKAYLEFF 539
[58][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 124 bits (311), Expect = 3e-27
Identities = 64/150 (42%), Positives = 94/150 (62%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSYI RT+ W++FP GRWG+S S ++G L D+ + + ++ ++L + W L S
Sbjct: 409 ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTS 468
Query: 237 VEDIQEKFKELCLGNLKSS-------PWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + E F G + PW++ + L ET ++ E+L++VN +G LTINSQP
Sbjct: 469 EESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINSQP 527
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
++N + S P VGWG GYV+QKAYLEFF
Sbjct: 528 NINGKPSSDPIVGWGPSGGYVFQKAYLEFF 557
[59][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 124 bits (311), Expect = 3e-27
Identities = 64/150 (42%), Positives = 94/150 (62%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSYI RT+ W++FP GRWG+S S ++G L D+ + + ++ ++L + W L S
Sbjct: 368 ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTS 427
Query: 237 VEDIQEKFKELCLGNLKSS-------PWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + E F G + PW++ + L ET ++ E+L++VN +G LTINSQP
Sbjct: 428 EESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINSQP 486
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
++N + S P VGWG GYV+QKAYLEFF
Sbjct: 487 NINGKPSSDPIVGWGPSGGYVFQKAYLEFF 516
[60][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 124 bits (311), Expect = 3e-27
Identities = 63/150 (42%), Positives = 94/150 (62%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSYI RT+ W++FP GRWG+S S ++G L D+ + + ++ ++L + W L S
Sbjct: 367 ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTS 426
Query: 237 VEDIQEKFKELCLGNLKSS-------PWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + + F G + PW++ + L ET ++ E+L++VN +G LTINSQP
Sbjct: 427 EESVFQVFAHHLSGEPNQNGYKVTCLPWND-EPLAAETSLMKEELLRVNRRGILTINSQP 485
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
++N + S P VGWG GYV+QKAYLEFF
Sbjct: 486 NINGKPSSDPIVGWGPSGGYVFQKAYLEFF 515
[61][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 124 bits (310), Expect = 4e-27
Identities = 62/140 (44%), Positives = 84/140 (60%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR +SY++RT+ W++FP GRWGDSRS ++G L + ++ ++ W P+ + D
Sbjct: 327 NRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDSYGIGLKGTNEQNVKL-WGSPM-CIRD 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ + F G L S PWSE + E I LI +N +GFLTINSQP+VN +S P
Sbjct: 385 LSDLFVRYMEGKLDSLPWSE-QAITTEAGPIRSDLIDLNRRGFLTINSQPAVNGAKSSDP 443
Query: 426 TVGWGGPVGYVYQKAYLEFF 485
GWG GYVYQKAYLE F
Sbjct: 444 VFGWGPRNGYVYQKAYLEVF 463
[62][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 123 bits (308), Expect = 7e-27
Identities = 64/150 (42%), Positives = 93/150 (62%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSYI RT+ W++FP GRWG+S S ++G L D+ + + ++ + L + W L S
Sbjct: 391 ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEELTS 450
Query: 237 VEDIQEKFKELCLGNLKSS-------PWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + E F G + PW++ + L ET ++ E+L++VN +G LTINSQP
Sbjct: 451 EESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINSQP 509
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
++N + S P VGWG GYV+QKAYLEFF
Sbjct: 510 NINGKPSSDPVVGWGPSGGYVFQKAYLEFF 539
[63][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 123 bits (308), Expect = 7e-27
Identities = 64/150 (42%), Positives = 93/150 (62%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSYI RT+ W++FP GRWG+S S ++G L D+ + + ++ + L + W L S
Sbjct: 409 ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEELTS 468
Query: 237 VEDIQEKFKELCLGNLKSS-------PWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + E F G + PW++ + L ET ++ E+L++VN +G LTINSQP
Sbjct: 469 EESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINSQP 527
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
++N + S P VGWG GYV+QKAYLEFF
Sbjct: 528 NINGKPSSDPVVGWGPSGGYVFQKAYLEFF 557
[64][TOP]
>UniRef100_UPI0000123E6B Hypothetical protein CBG12960 n=1 Tax=Caenorhabditis briggsae AF16
RepID=UPI0000123E6B
Length = 662
Score = 123 bits (308), Expect = 7e-27
Identities = 67/150 (44%), Positives = 90/150 (60%), Gaps = 11/150 (7%)
Frame = +3
Query: 69 RPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRP---RARDKKLQQEWVVPLKSV 239
RP+SYI+RT+ W+ FP GRWG+S S ++G +S + S R D +L + ++S+
Sbjct: 385 RPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLSNLTTLRNGDDRLSM-FGENIESI 443
Query: 240 EDIQEKFKELCLGNLKSS-------PWSELD-GLQPETRIINEQLIKVNSKGFLTINSQP 395
ED++ F S PW+E + G+QPET +I+EQL+ N G LT+NSQP
Sbjct: 444 EDVKRVFINYITQTPNVSGKKVTVLPWTEAETGVQPETSLISEQLVWCNENGILTVNSQP 503
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
SVN S P VGWG P GY YQKAYLE F
Sbjct: 504 SVNGAPSTDPLVGWGKPGGYCYQKAYLECF 533
[65][TOP]
>UniRef100_A8XGR9 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis briggsae
RepID=A8XGR9_CAEBR
Length = 724
Score = 123 bits (308), Expect = 7e-27
Identities = 67/150 (44%), Positives = 90/150 (60%), Gaps = 11/150 (7%)
Frame = +3
Query: 69 RPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRP---RARDKKLQQEWVVPLKSV 239
RP+SYI+RT+ W+ FP GRWG+S S ++G +S + S R D +L + ++S+
Sbjct: 435 RPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLSNLTTLRNGDDRLSM-FGENIESI 493
Query: 240 EDIQEKFKELCLGNLKSS-------PWSELD-GLQPETRIINEQLIKVNSKGFLTINSQP 395
ED++ F S PW+E + G+QPET +I+EQL+ N G LT+NSQP
Sbjct: 494 EDVKRVFINYITQTPNVSGKKVTVLPWTEAETGVQPETSLISEQLVWCNENGILTVNSQP 553
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
SVN S P VGWG P GY YQKAYLE F
Sbjct: 554 SVNGAPSTDPLVGWGKPGGYCYQKAYLECF 583
[66][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 123 bits (308), Expect = 7e-27
Identities = 64/150 (42%), Positives = 93/150 (62%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSYI RT+ W++FP GRWG+S S ++G L D+ + + ++ + L + W L S
Sbjct: 368 ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEELTS 427
Query: 237 VEDIQEKFKELCLGNLKSS-------PWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + E F G + PW++ + L ET ++ E+L++VN +G LTINSQP
Sbjct: 428 EESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINSQP 486
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
++N + S P VGWG GYV+QKAYLEFF
Sbjct: 487 NINGKPSSDPVVGWGPSGGYVFQKAYLEFF 516
[67][TOP]
>UniRef100_UPI000151BABB hypothetical protein PGUG_04648 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151BABB
Length = 355
Score = 122 bits (306), Expect = 1e-26
Identities = 63/141 (44%), Positives = 85/141 (60%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR SYISRT W++FP GRWGDSRS ++G + R K+ W P +S +D
Sbjct: 71 NRKYSYISRTSTWDEFPNGRWGDSRSPAFGDIDLFAADLLRQSPKRAFDLWGCP-QSFKD 129
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ +LKS PWS+ + +T II ++LI +N +GFLT+NSQPS+N +S+
Sbjct: 130 LSNLVVSYLKNDLKSLPWSD-GPIGEDTAIIVDKLISLNQRGFLTMNSQPSLNCVKSNDK 188
Query: 426 TVGWGGPVGYVYQKAYLEFFC 488
GWG GYV+QK YLEFFC
Sbjct: 189 VYGWGPKNGYVFQKQYLEFFC 209
[68][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 122 bits (306), Expect = 1e-26
Identities = 64/141 (45%), Positives = 86/141 (60%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
+R SYISRT W++FP GRWGDSRS ++G + R KK + W +P +S+ D
Sbjct: 331 HRKYSYISRTATWDEFPNGRWGDSRSPAFGDIDLCASELLRQSPKKAFELWGLP-QSLAD 389
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ G+LKS PWS+ + +TR+I + LI +N GF T+NSQP++NA +S
Sbjct: 390 LSGIIINYLKGDLKSLPWSD-GPVGDDTRVIVDDLIYLNQHGFFTMNSQPALNAVKSSEK 448
Query: 426 TVGWGGPVGYVYQKAYLEFFC 488
GWG GYVYQK YLEFFC
Sbjct: 449 VFGWGPKNGYVYQKQYLEFFC 469
[69][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 122 bits (306), Expect = 1e-26
Identities = 62/143 (43%), Positives = 89/143 (62%), Gaps = 2/143 (1%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVP--LKSV 239
NR SY+SRT W++FP GRWGDSRS ++G + R K+ + W P LK +
Sbjct: 332 NRKYSYVSRTATWDEFPNGRWGDSRSPAFGDIDLCASELLRQSPKRAYELWGTPGSLKEL 391
Query: 240 EDIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSD 419
DI + + G+LKS PWS+ + +T++I + L+++N +G LT+NSQP++N+ +S
Sbjct: 392 SDIVISYLK---GDLKSLPWSD-GSVGDDTKVIVDDLVELNKRGLLTMNSQPALNSIKSS 447
Query: 420 SPTVGWGGPVGYVYQKAYLEFFC 488
GWG GYVYQK YLEFFC
Sbjct: 448 EKIFGWGPKNGYVYQKQYLEFFC 470
[70][TOP]
>UniRef100_A5DMZ7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DMZ7_PICGU
Length = 355
Score = 122 bits (306), Expect = 1e-26
Identities = 63/141 (44%), Positives = 85/141 (60%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR SYISRT W++FP GRWGDSRS ++G + R K+ W P +S +D
Sbjct: 71 NRKYSYISRTSTWDEFPNGRWGDSRSPAFGDIDLFAADLLRQSPKRAFDLWGCP-QSFKD 129
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ +LKS PWS+ + +T II ++LI +N +GFLT+NSQPS+N +S+
Sbjct: 130 LSNLVVSYLKNDLKSLPWSD-GPIGEDTAIIVDKLISLNQRGFLTMNSQPSLNCVKSNDK 188
Query: 426 TVGWGGPVGYVYQKAYLEFFC 488
GWG GYV+QK YLEFFC
Sbjct: 189 VYGWGPKNGYVFQKQYLEFFC 209
[71][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 122 bits (305), Expect = 2e-26
Identities = 63/150 (42%), Positives = 93/150 (62%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQ--FSRPRARDKKLQQEWVVPLKS 236
A+RPKSYI RT+ W++FP GRWG+S S ++G L D+ + + ++ ++L + W L S
Sbjct: 398 ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTS 457
Query: 237 VEDIQEKFKELCLGNLKSS-------PWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
+ E F G + PW++ + L ET ++ E+L++VN +G LTINSQP
Sbjct: 458 EASVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINSQP 516
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
++N + S P VGWG GYV+QKAYLEFF
Sbjct: 517 NINGKPSSDPIVGWGPSGGYVFQKAYLEFF 546
[72][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 121 bits (304), Expect = 2e-26
Identities = 64/150 (42%), Positives = 92/150 (61%), Gaps = 9/150 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFS--RPRARDKKLQQEWVVPLKS 236
A+RPKSYI RT+ W++FP GRWG+S S ++G L ++ + ++ ++L + W L S
Sbjct: 365 ASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKNYYLFCLKSKSPREELLKMWGQELTS 424
Query: 237 VEDIQEKFKELCLGNLKSS-------PWSELDGLQPETRIINEQLIKVNSKGFLTINSQP 395
E + E F G + PW++ + L ET ++ E+L KVN +G LTINSQP
Sbjct: 425 EESVFEVFAYYLSGEPNQNGYKVTCLPWND-EPLAAETSLLKEELQKVNRRGILTINSQP 483
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
++N + S P VGWG GYV+QKAYLEFF
Sbjct: 484 NINGKPSADPVVGWGPSGGYVFQKAYLEFF 513
[73][TOP]
>UniRef100_Q8MQE7 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis elegans
RepID=Q8MQE7_CAEEL
Length = 642
Score = 121 bits (304), Expect = 2e-26
Identities = 66/150 (44%), Positives = 89/150 (59%), Gaps = 11/150 (7%)
Frame = +3
Query: 69 RPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSR---PRARDKKLQQEWVVPLKSV 239
RP+SYI+RT+ W+ FP GRWG+S S ++G +S + S R D +L + ++S
Sbjct: 363 RPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLSNLTTVRNADDRLAM-FGANIESF 421
Query: 240 EDIQEKFKELCLGNLKSS-------PWSELD-GLQPETRIINEQLIKVNSKGFLTINSQP 395
ED++ F + PW+E + G+QPET +I+EQL+ N G LT+NSQP
Sbjct: 422 EDVKRVFINYITQAPNADGVKVTVLPWTEAETGVQPETSLISEQLVWCNENGILTVNSQP 481
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
SVN S P VGWG P GY YQKAYLE F
Sbjct: 482 SVNGAPSTDPLVGWGKPGGYCYQKAYLECF 511
[74][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 121 bits (304), Expect = 2e-26
Identities = 61/138 (44%), Positives = 87/138 (63%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
+R +SY++RT+ W++FP GRW DSRS ++G L + ++ ++ W P KSV+D
Sbjct: 327 HRHQSYVARTQSWDEFPNGRWTDSRSPAFGELDVYGIGLKGTNEQNIKL-WGEP-KSVKD 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ + F G L PWSE + E+ II + LI +N++GFLTINSQP++N +S P
Sbjct: 385 LSDIFIRFLEGKLDRLPWSE-SAITQESDIIKDDLIALNNRGFLTINSQPAINGAKSSHP 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG GYVYQKAYLE
Sbjct: 444 IYGWGPKNGYVYQKAYLE 461
[75][TOP]
>UniRef100_Q17693 Probable methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis
elegans RepID=MTHR_CAEEL
Length = 663
Score = 121 bits (304), Expect = 2e-26
Identities = 66/150 (44%), Positives = 89/150 (59%), Gaps = 11/150 (7%)
Frame = +3
Query: 69 RPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSR---PRARDKKLQQEWVVPLKSV 239
RP+SYI+RT+ W+ FP GRWG+S S ++G +S + S R D +L + ++S
Sbjct: 384 RPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLSNLTTVRNADDRLAM-FGANIESF 442
Query: 240 EDIQEKFKELCLGNLKSS-------PWSELD-GLQPETRIINEQLIKVNSKGFLTINSQP 395
ED++ F + PW+E + G+QPET +I+EQL+ N G LT+NSQP
Sbjct: 443 EDVKRVFINYITQAPNADGVKVTVLPWTEAETGVQPETSLISEQLVWCNENGILTVNSQP 502
Query: 396 SVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
SVN S P VGWG P GY YQKAYLE F
Sbjct: 503 SVNGAPSTDPLVGWGKPGGYCYQKAYLECF 532
[76][TOP]
>UniRef100_UPI0000ECA34F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Gallus
gallus RepID=UPI0000ECA34F
Length = 640
Score = 121 bits (303), Expect = 3e-26
Identities = 66/151 (43%), Positives = 89/151 (58%), Gaps = 10/151 (6%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRAR---DKKLQQEWVVPLK 233
A+RPKSYI RT+ W+DFP GRWG+S S ++G L D+ ++ ++L + W L
Sbjct: 358 ASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSSLPPREELLKMWGEELT 417
Query: 234 SVEDIQEKFKELCLGNLKSS-------PWSELDGLQPETRIINEQLIKVNSKGFLTINSQ 392
E + E F G + PW++ D L ET ++ EQL KVN +G LTINSQ
Sbjct: 418 GEESVFEVFTCYITGEPNKNGHRVTCMPWND-DPLATETSLLKEQLEKVNRRGILTINSQ 476
Query: 393 PSVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
P++N + S P GWG GYV+QKAYLEFF
Sbjct: 477 PNINGKPSTDPIFGWGPSGGYVFQKAYLEFF 507
[77][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 121 bits (303), Expect = 3e-26
Identities = 62/140 (44%), Positives = 84/140 (60%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR SYI+RT+ W++FP GRW DSRS ++G L + ++ ++ W P KS+ D
Sbjct: 327 NRNSSYIARTQIWDEFPNGRWTDSRSPAFGELDAYGIGLKGTNEQNIKL-WGEP-KSIRD 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
I + F G L+ PWS+ + E I E LI++N +G LT+NSQP+VN RS P
Sbjct: 385 ISQIFVRYVEGKLERLPWSD-SPISAEANAIKENLIELNGRGLLTVNSQPAVNGVRSSHP 443
Query: 426 TVGWGGPVGYVYQKAYLEFF 485
GWG G+VYQKAYLE F
Sbjct: 444 VYGWGPKNGFVYQKAYLELF 463
[78][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 120 bits (302), Expect = 4e-26
Identities = 62/138 (44%), Positives = 86/138 (62%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR KSY+ RT+ W++FP GRWGDSRS ++G L + + + +++W P K+++D
Sbjct: 327 NRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGSNEAN-RKKWGEP-KAIQD 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
I E F ++S PWSE L E I + LI++N +G LTINSQP+VN +S P
Sbjct: 385 IAELFVSYLNNKIESLPWSE-SPLTTEADEIRDDLIELNKRGLLTINSQPAVNGVKSSHP 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG GYVYQK+YLE
Sbjct: 444 IHGWGPDNGYVYQKSYLE 461
[79][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 120 bits (302), Expect = 4e-26
Identities = 61/138 (44%), Positives = 88/138 (63%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR +SY++RT+ W++FP GRWGDSRS ++G L + R +K+ + W P K+V+D
Sbjct: 327 NRKQSYVARTQDWDEFPNGRWGDSRSPAFGELETYGVLL-RQSPQKVLELWGEP-KTVDD 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
++ G L S PWS++ + E I Q++++N++G LTINSQP+VN +S P
Sbjct: 385 LKTLLVNYLNGKLASLPWSDVP-ISNEIETIKPQILELNNRGILTINSQPAVNGAKSTHP 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG GYVYQKAYLE
Sbjct: 444 VHGWGPKNGYVYQKAYLE 461
[80][TOP]
>UniRef100_Q3EAG8 Methylenetetrahydrofolate reductase n=1 Tax=Arabidopsis thaliana
RepID=Q3EAG8_ARATH
Length = 407
Score = 120 bits (301), Expect = 5e-26
Identities = 52/65 (80%), Positives = 59/65 (90%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
ANRPKSYISRTKGW DFP GRWGDS SA+Y LSD+QF+RP+ RDKKLQQEWVVPLKS+E
Sbjct: 333 ANRPKSYISRTKGWNDFPHGRWGDSHSAAYSTLSDYQFARPKGRDKKLQQEWVVPLKSIE 392
Query: 243 DIQEK 257
D+QE+
Sbjct: 393 DVQER 397
[81][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 120 bits (301), Expect = 5e-26
Identities = 61/140 (43%), Positives = 84/140 (60%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR SYI+RT+ W++FP GRW DSRS ++G L + ++ ++ W P KS+ D
Sbjct: 327 NRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDAYGIGLKGTNEQNIKL-WGEP-KSIRD 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
I + F G L PWS+ + E I + L+++NS+G LT+NSQP+VN RS P
Sbjct: 385 ITQIFVRYLEGKLDRLPWSD-SPISGEANAIKDNLVQLNSRGLLTVNSQPAVNGVRSSHP 443
Query: 426 TVGWGGPVGYVYQKAYLEFF 485
GWG G+VYQKAYLE F
Sbjct: 444 VFGWGPKNGFVYQKAYLELF 463
[82][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 120 bits (301), Expect = 5e-26
Identities = 61/140 (43%), Positives = 84/140 (60%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR SYI+RT+ W++FP GRW DSRS ++G L + ++ ++ W P KS+ D
Sbjct: 327 NRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDAYGIGLKGTNEQNIKL-WGEP-KSIRD 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
I + F G L PWS+ + E I + L+++NS+G LT+NSQP+VN RS P
Sbjct: 385 ITQIFVRYLEGKLDRLPWSD-SPISGEANAIKDNLVQLNSRGLLTVNSQPAVNGVRSSHP 443
Query: 426 TVGWGGPVGYVYQKAYLEFF 485
GWG G+VYQKAYLE F
Sbjct: 444 VFGWGPKNGFVYQKAYLELF 463
[83][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 120 bits (300), Expect = 6e-26
Identities = 67/142 (47%), Positives = 82/142 (57%), Gaps = 2/142 (1%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVP--LKSV 239
NR SYISRT W++FP GRWGDSRS ++G + R KK W P LK
Sbjct: 331 NRKYSYISRTSTWDEFPNGRWGDSRSPAFGDIDLFATDLLRQSPKKAFDLWGHPGTLKQF 390
Query: 240 EDIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSD 419
DI F G L S PWS+ + ++ II + LI +N KGF T+NSQPS+NA +S+
Sbjct: 391 SDIIISFLS---GKLNSLPWSD-SAIGQDSEIIVDNLIALNKKGFFTLNSQPSLNAIKSN 446
Query: 420 SPTVGWGGPVGYVYQKAYLEFF 485
GWG GYVYQK YLEFF
Sbjct: 447 DKVYGWGPKNGYVYQKQYLEFF 468
[84][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 120 bits (300), Expect = 6e-26
Identities = 65/156 (41%), Positives = 86/156 (55%), Gaps = 16/156 (10%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQF----------SRPRARDKKLQQE 215
NRP+SYI+RT W++FP GRWGD RS ++G LSD+ +
Sbjct: 327 NRPRSYIARTGSWDEFPNGRWGDYRSPAFGDLSDYHLGGVTPPPGGSANNNTTTTTTGDS 386
Query: 216 WVVPL------KSVEDIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFL 377
VVP +S +D+ F C GN+K PW++ L E+ I EQL+ +N GFL
Sbjct: 387 VVVPNIYGDSPQSEQDVYNVFASYCSGNIKRLPWND-SPLSLESENIKEQLVFLNKNGFL 445
Query: 378 TINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
TINSQP++N S GWGG G VY+KAY+EFF
Sbjct: 446 TINSQPAINGLPSTDKQHGWGGKNGIVYKKAYIEFF 481
[85][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 120 bits (300), Expect = 6e-26
Identities = 67/142 (47%), Positives = 82/142 (57%), Gaps = 2/142 (1%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVP--LKSV 239
NR SYISRT W++FP GRWGDSRS ++G + R KK W P LK
Sbjct: 331 NRKYSYISRTSTWDEFPNGRWGDSRSPAFGDIDLFATDLLRQSPKKAFDLWGHPGTLKQF 390
Query: 240 EDIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSD 419
DI F G L S PWS+ + ++ II + LI +N KGF T+NSQPS+NA +S+
Sbjct: 391 SDIIISFLS---GKLNSLPWSD-SAIGQDSEIIVDNLIALNKKGFFTLNSQPSLNAIKSN 446
Query: 420 SPTVGWGGPVGYVYQKAYLEFF 485
GWG GYVYQK YLEFF
Sbjct: 447 DKVYGWGPKNGYVYQKQYLEFF 468
[86][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 120 bits (300), Expect = 6e-26
Identities = 60/140 (42%), Positives = 84/140 (60%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR SYI+RT+ W++FP GRW DSRS ++G L + ++ ++ W P KS+ D
Sbjct: 327 NRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDAYGIGLKGTNEQNIKL-WGEP-KSIRD 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ + F G L PWS+ + E I + L+++NS+G LT+NSQP+VN RS P
Sbjct: 385 VTQIFVRYLEGKLDRLPWSD-SPISGEANAIKDNLVQLNSRGLLTVNSQPAVNGVRSSHP 443
Query: 426 TVGWGGPVGYVYQKAYLEFF 485
GWG G+VYQKAYLE F
Sbjct: 444 VFGWGPKNGFVYQKAYLELF 463
[87][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 119 bits (299), Expect = 8e-26
Identities = 62/141 (43%), Positives = 86/141 (60%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
+R SYISRT W++FP GRWGDSRS ++G + R KK + W +P +S+ +
Sbjct: 331 HRKYSYISRTATWDEFPNGRWGDSRSPAFGDIDLCASELLRQSPKKAFELWGLP-QSLAE 389
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ G+LKS PWS+ + +T++I + LI +N GF T+NSQP++NA +S
Sbjct: 390 LSGIIINYLKGDLKSLPWSD-GPVGDDTKVIVDDLIYLNQHGFFTMNSQPALNAVKSSEK 448
Query: 426 TVGWGGPVGYVYQKAYLEFFC 488
GWG GYVYQK YLEFFC
Sbjct: 449 VFGWGPKNGYVYQKQYLEFFC 469
[88][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 119 bits (299), Expect = 8e-26
Identities = 60/138 (43%), Positives = 84/138 (60%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR SY++RT+ W+++P GRW DSRS ++G L + ++ ++ W P KS++D
Sbjct: 327 NRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDAYGVGLKGTNEQNIKL-WGEP-KSIKD 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
I + F G L PWS+ + E I E L+K+N +GFLTINSQP+VN +S P
Sbjct: 385 ISDIFVNFLTGKLDRLPWSD-SPITTEAHEIQEDLLKLNQRGFLTINSQPAVNGVKSSHP 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG G+VYQKAYLE
Sbjct: 444 VYGWGPKNGFVYQKAYLE 461
[89][TOP]
>UniRef100_Q9SE60-2 Isoform 2 of Methylenetetrahydrofolate reductase 1 n=1
Tax=Arabidopsis thaliana RepID=Q9SE60-2
Length = 421
Score = 119 bits (299), Expect = 8e-26
Identities = 52/64 (81%), Positives = 58/64 (90%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
ANRPKSYISRTKGW DFP GRWGDS SA+Y LSD+QF+RP+ RDKKLQQEWVVPLKS+E
Sbjct: 333 ANRPKSYISRTKGWNDFPHGRWGDSHSAAYSTLSDYQFARPKGRDKKLQQEWVVPLKSIE 392
Query: 243 DIQE 254
D+QE
Sbjct: 393 DVQE 396
[90][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 119 bits (298), Expect = 1e-25
Identities = 60/141 (42%), Positives = 83/141 (58%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR SY++RT W++FP GRWGDSRS ++G + R K+ Q+ W +P +++ D
Sbjct: 331 NRKYSYVTRTATWDEFPNGRWGDSRSPAFGDIDLCASELLRQSPKRAQELWGLP-QTISD 389
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
I G L S PW + + +T II + LI++N +T+NSQPS+N+ RS
Sbjct: 390 ITGLVISYLKGQLNSLPWFD-GAIGEDTNIILDHLIELNENSLITLNSQPSLNSVRSSDK 448
Query: 426 TVGWGGPVGYVYQKAYLEFFC 488
GWG GYVYQK YLEFFC
Sbjct: 449 VFGWGPKNGYVYQKQYLEFFC 469
[91][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 119 bits (298), Expect = 1e-25
Identities = 60/138 (43%), Positives = 83/138 (60%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR SYI+RT+ W++FP GRW DSRS ++G L + ++ +Q W P KS++D
Sbjct: 327 NRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDSYGIGLKGTNEQNIQL-WGEP-KSIKD 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ F G L PWS+ + E + I LI++N++G LTINSQP+VN +S P
Sbjct: 385 LSRLFVRYLEGKLSRLPWSDTP-ISSEAKAIKPNLIELNNRGILTINSQPAVNGAKSSHP 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG G+VYQKAYLE
Sbjct: 444 VYGWGPKNGFVYQKAYLE 461
[92][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 118 bits (296), Expect = 2e-25
Identities = 61/138 (44%), Positives = 86/138 (62%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR KSYI+RT+ W++FP GRWGDSRS ++G L + + + +++W P ++V+D
Sbjct: 327 NRNKSYITRTQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGSNELN-RKKWGEP-QTVKD 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
I F L+ PWSE + E +I + LI +N++G +TINSQP+VN +S P
Sbjct: 385 IANLFVRYLNQELEYLPWSEAP-ISSEAELIKDDLIALNNRGLITINSQPAVNGVKSTHP 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG GYVYQKAYLE
Sbjct: 444 VHGWGPANGYVYQKAYLE 461
[93][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 118 bits (296), Expect = 2e-25
Identities = 61/138 (44%), Positives = 83/138 (60%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR SYI+RT W++FP GRW DSRS ++G L + ++ ++ W P S+ D
Sbjct: 327 NRNSSYIARTAIWDEFPNGRWTDSRSPAFGELELYGVGLKGTNEQNIKL-WGEP-NSLRD 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ E F GNL PWS+ + PET I + L+++N +GF TINSQP+VN +S P
Sbjct: 385 LAEVFVRFLEGNLDRLPWSD-SPITPETSAIKDALVELNRRGFFTINSQPAVNGVKSSHP 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG G+VYQKAYLE
Sbjct: 444 VFGWGPKNGFVYQKAYLE 461
[94][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 118 bits (296), Expect = 2e-25
Identities = 60/138 (43%), Positives = 84/138 (60%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
+R +SY++RT+ W++FP GRW DSRS ++G L + ++ ++ W P KS++D
Sbjct: 327 HRHQSYVARTQTWDEFPNGRWTDSRSPAFGELDVYGIGLKGTNEQNIKL-WGEP-KSIKD 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ F L PWSE + ET II + LI +N++GFLTINSQP++N S P
Sbjct: 385 LSSIFVRFLEAKLDRLPWSE-SSITEETDIIKQDLIDLNNRGFLTINSQPAINGASSSHP 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG GYVYQKAYLE
Sbjct: 444 VYGWGPKNGYVYQKAYLE 461
[95][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 118 bits (296), Expect = 2e-25
Identities = 59/138 (42%), Positives = 86/138 (62%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR SYI+RT W+++P GRW D+RS ++G L+ + ++ ++ W P KS++D
Sbjct: 328 NRNASYIARTADWDEYPNGRWTDARSPAFGELNAYGVRLKGTNEQNIKL-WGAP-KSIKD 385
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ + F G ++ PWS+ + PET I +L+ +N +GFLTINSQP+VN +S P
Sbjct: 386 LSDIFVRYLNGKVERLPWSD-SAVTPETSDIQNELLDLNKRGFLTINSQPAVNGVKSTDP 444
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG GYVYQKAYLE
Sbjct: 445 VHGWGPRNGYVYQKAYLE 462
[96][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 118 bits (295), Expect = 2e-25
Identities = 60/138 (43%), Positives = 85/138 (61%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
+R +SY++RT+ W+++P GRW DSRS ++G L + ++ +Q W P KS+++
Sbjct: 327 HRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYGIGLKGTNEQNIQL-WGKP-KSLKE 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ E F G L PWSE + ET II L+ +NS+GFLTINSQP+++ S P
Sbjct: 385 LSEIFIHFLNGKLDRLPWSE-GAVTEETDIIKRDLLDLNSRGFLTINSQPAIDGVHSSHP 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG GYVYQKAYLE
Sbjct: 444 VYGWGPKNGYVYQKAYLE 461
[97][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 118 bits (295), Expect = 2e-25
Identities = 60/138 (43%), Positives = 85/138 (61%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
+R +SY++RT+ W+++P GRW DSRS ++G L + ++ +Q W P KS+++
Sbjct: 327 HRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYGIGLKGTNEQNIQL-WGKP-KSLKE 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ E F G L PWSE + ET II L+ +NS+GFLTINSQP+++ S P
Sbjct: 385 LSEIFIRFLNGKLDRLPWSE-GAVTEETDIIKRDLLDLNSRGFLTINSQPAIDGVHSSHP 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG GYVYQKAYLE
Sbjct: 444 VYGWGPKNGYVYQKAYLE 461
[98][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 118 bits (295), Expect = 2e-25
Identities = 60/138 (43%), Positives = 85/138 (61%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
+R +SY++RT+ W+++P GRW DSRS ++G L + ++ +Q W P KS+++
Sbjct: 327 HRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYGIGLKGTNEQNIQL-WGKP-KSLKE 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ E F G L PWSE + ET II L+ +NS+GFLTINSQP+++ S P
Sbjct: 385 LSEIFIRFLNGKLDRLPWSE-GAVTEETDIIKRDLLDLNSRGFLTINSQPAIDGVHSSHP 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG GYVYQKAYLE
Sbjct: 444 VYGWGPKNGYVYQKAYLE 461
[99][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 117 bits (292), Expect = 5e-25
Identities = 59/138 (42%), Positives = 82/138 (59%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR SYI+RT+ W++FP GRW DSRS ++G L + ++ ++ W P KS+ D
Sbjct: 327 NRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDSYGIGLKGTNEQNIKL-WGEP-KSIRD 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ F + G L PWS+ + E I ++LI++N +G TINSQP+VN RS P
Sbjct: 385 LAHIFVKFMQGELARLPWSDTP-ISGEANAIKDKLIELNKRGLFTINSQPAVNGARSSHP 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG G+VYQKAYLE
Sbjct: 444 VYGWGPKNGFVYQKAYLE 461
[100][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 117 bits (292), Expect = 5e-25
Identities = 63/138 (45%), Positives = 84/138 (60%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR KSY+ RT+ W++FP GRWGDSRS ++G L + ++ ++++ P KSV+D
Sbjct: 322 NRNKSYVMRTQDWDEFPNGRWGDSRSPAFGELDAYGIGLLGTNEQN-RKKFGEP-KSVKD 379
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
I F + + PWSE L E I + LI +N +G +TINSQP+VN RS P
Sbjct: 380 IATLFVRYVQKEVDTLPWSE-SPLDAEAEQIRDDLIDLNLRGLITINSQPAVNGVRSTHP 438
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG P GYVYQKAYLE
Sbjct: 439 IHGWGPPNGYVYQKAYLE 456
[101][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 116 bits (291), Expect = 7e-25
Identities = 58/138 (42%), Positives = 87/138 (63%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR KSY++RT+ W++FP GRWGDSRS ++G L + + ++ +++W P S++D
Sbjct: 327 NRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDAYGVGLTGSNEQN-RKKWGEPT-SIKD 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
I F ++ PWSE + E +I + LI++N++G +T+NSQP+VN +S P
Sbjct: 385 IANLFVRYLNKEIEYLPWSEAP-VAEEADLIKDDLIELNNRGLITVNSQPAVNGVKSTHP 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG GYVYQKAYLE
Sbjct: 444 IHGWGPANGYVYQKAYLE 461
[102][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 116 bits (291), Expect = 7e-25
Identities = 61/138 (44%), Positives = 84/138 (60%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
+R +SY++RT+ W++FP GRW DSRS ++G L + ++ ++ W P KS++D
Sbjct: 327 HRHQSYVARTQTWDEFPNGRWTDSRSPAFGELDVYGIGLKGTNEQNIKL-WGEP-KSIKD 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ F G L PWSE + ET I + LI +N++GFLTINSQP+VN S P
Sbjct: 385 LSAIFIRFLEGGLDRLPWSE-SPITEETDDIKQDLIDLNNRGFLTINSQPAVNGMSSSHP 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG GYVYQKAYLE
Sbjct: 444 VYGWGPKNGYVYQKAYLE 461
[103][TOP]
>UniRef100_B2B6X0 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B6X0_PODAN
Length = 691
Score = 116 bits (290), Expect = 9e-25
Identities = 61/134 (45%), Positives = 83/134 (61%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS +YG + + S + L+ W P ++ EDI F
Sbjct: 428 LGREATWDDFPNGRWGDARSPAYGQIDGYGVSLHVTVAQALRI-WGTP-RTTEDINNVFI 485
Query: 264 ELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGG 443
G L + PWSE +G PET I +QLIK+NSKG+ ++ SQP+VN RS PT GWG
Sbjct: 486 RHLKGELTTIPWSE-EGFSPETDKIRDQLIKLNSKGWWSLASQPAVNGLRSSDPTFGWGP 544
Query: 444 PVGYVYQKAYLEFF 485
G+V+QKA++EFF
Sbjct: 545 ANGFVFQKAFVEFF 558
[104][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 115 bits (289), Expect = 1e-24
Identities = 65/150 (43%), Positives = 88/150 (58%), Gaps = 15/150 (10%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKK--LQQEWVVPLKS 236
A+RPKSYI RT+ W+DFP GRWG+S S ++G L+D+ +++ K L Q W L S
Sbjct: 372 ASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALLQMWGEELLS 431
Query: 237 VEDIQEKF-------------KELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFL 377
E + E F K LCL PW++ + L ET ++ ++L KVN +G L
Sbjct: 432 EESVFEVFTFYITAQSNRCGQKVLCL------PWND-EPLAQETNLLKDELEKVNRRGVL 484
Query: 378 TINSQPSVNAERSDSPTVGWGGPVGYVYQK 467
TINSQP++N + S P VGWG GYVYQK
Sbjct: 485 TINSQPNINGKPSTDPIVGWGPAGGYVYQK 514
[105][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 115 bits (289), Expect = 1e-24
Identities = 64/143 (44%), Positives = 82/143 (57%), Gaps = 2/143 (1%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSD--HQFSRPRARDKKLQQEWVVPLKS 236
+NRPKSY+ RT W++FP GRWGDS S ++G LSD H S D+ + ++
Sbjct: 323 SNRPKSYVMRTDDWDEFPNGRWGDSTSPAFGELSDLSHFCSFTLGSDEDRRAMLGHNPQA 382
Query: 237 VEDIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERS 416
D+ E F G++ PW E LQPE+ +I QL K+N GFLT+NSQP V+ S
Sbjct: 383 ESDVYEVFARYVEGSVPHIPWCETP-LQPESFLIQPQLAKLNRYGFLTVNSQPPVDGLPS 441
Query: 417 DSPTVGWGGPVGYVYQKAYLEFF 485
GWGG G VYQKAY E F
Sbjct: 442 CHKVFGWGGKGGRVYQKAYFECF 464
[106][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 115 bits (289), Expect = 1e-24
Identities = 61/138 (44%), Positives = 83/138 (60%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
+R +SY++RT+ W++FP GRW DSRS ++G L + ++ ++ W P KS++D
Sbjct: 327 HRHQSYVARTQTWDEFPNGRWTDSRSPAFGELDVYGIGLKGTNEQNIKL-WGEP-KSIKD 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ F G L PWSE + ET I LI +N++GFLTINSQP+VN S P
Sbjct: 385 LSAIFIRFLEGGLDRLPWSE-SPITEETDDIKHDLIDLNNRGFLTINSQPAVNGMSSSHP 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG GYVYQKAYLE
Sbjct: 444 VYGWGPKNGYVYQKAYLE 461
[107][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 115 bits (289), Expect = 1e-24
Identities = 59/138 (42%), Positives = 83/138 (60%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR KSY+ RT+ W++FP GRWGDSRS ++G L + + +++W P K+V+D
Sbjct: 327 NRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGTNEAN-RKKWGEP-KTVQD 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
I + F + S PWSE L E I + L+++N +G LT+NSQP+VN +S
Sbjct: 385 IAQLFVRYLRNEIDSLPWSE-SPLTSEADEIRDDLVELNKRGLLTVNSQPAVNGVKSSHA 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG GYVYQK+YLE
Sbjct: 444 VHGWGPSNGYVYQKSYLE 461
[108][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 115 bits (289), Expect = 1e-24
Identities = 59/138 (42%), Positives = 85/138 (61%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
+R +SY++RT+ W+++P GRW DSRS ++G L + ++ ++ W P KS+++
Sbjct: 327 HRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYGIGLKGTNEQNIKL-WGEP-KSLKE 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ E F G+L PWSE + ET II L+ +N KGFLTINSQP+++ S P
Sbjct: 385 LSEIFIRFLNGSLDRLPWSE-GAVTEETEIIKSDLLDLNRKGFLTINSQPAIDGMPSSHP 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG GYVYQKAYLE
Sbjct: 444 IYGWGPKNGYVYQKAYLE 461
[109][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 115 bits (289), Expect = 1e-24
Identities = 59/138 (42%), Positives = 85/138 (61%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
+R +SY++RT+ W+++P GRW DSRS ++G L + ++ ++ W P KS+++
Sbjct: 327 HRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYGIGLKGTNEQNIKL-WGEP-KSLKE 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ E F G+L PWSE + ET II L+ +N KGFLTINSQP+++ S P
Sbjct: 385 LSEIFIRFLNGSLDRLPWSE-GAVTEETEIIKSDLLDLNRKGFLTINSQPAIDGMPSSHP 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG GYVYQKAYLE
Sbjct: 444 IYGWGPKNGYVYQKAYLE 461
[110][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 115 bits (289), Expect = 1e-24
Identities = 61/139 (43%), Positives = 86/139 (61%)
Frame = +3
Query: 69 RPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDI 248
R +S+ISRT+ W++FP GRWGDSRS ++G D + + D +++ W P +++ D+
Sbjct: 336 RSQSFISRTEQWDEFPNGRWGDSRSPAFGEF-DPKHHGLKQTDAEIRALWGSP-ENIRDL 393
Query: 249 QEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPT 428
F C L PWS++ L E+ II ++L ++N +G LTINSQP V A S P
Sbjct: 394 GNVFAAYCERKLACLPWSDIP-LSGESAIIADKLAELNRQGILTINSQPPVCAAPSTDPL 452
Query: 429 VGWGGPVGYVYQKAYLEFF 485
GWG GYV+QKAYLEFF
Sbjct: 453 FGWGPAHGYVFQKAYLEFF 471
[111][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 115 bits (288), Expect = 1e-24
Identities = 60/141 (42%), Positives = 84/141 (59%)
Frame = +3
Query: 63 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
+NR +YISRT W++FP GRWGDSRS ++G + R K+ + W P +S++
Sbjct: 323 SNRKFTYISRTSNWDEFPNGRWGDSRSPAFGEVDLCDGDLIRHSPKRAVELWGKP-QSID 381
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
D+ + F GNL S PWS+ + E ++ + L+ +N +G LTINSQP VN S+
Sbjct: 382 DVIDLFVRYLQGNLSSLPWSDGE-TSKEINVLLDDLLALNRQGILTINSQPCVNGLPSNH 440
Query: 423 PTVGWGGPVGYVYQKAYLEFF 485
GWG G+VYQK YLEFF
Sbjct: 441 NVHGWGPSNGFVYQKQYLEFF 461
[112][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 115 bits (287), Expect = 2e-24
Identities = 58/138 (42%), Positives = 85/138 (61%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
+R +SY++RT+ W+++P GRW DSRS ++G L + ++ ++ W P KS+++
Sbjct: 313 HRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYGIGLKGTNEQNIKL-WGEP-KSLKE 370
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ E F GNL PWSE + ET +I L+ +N +GFLTINSQP+++ S P
Sbjct: 371 LSEIFVRFLNGNLDRLPWSE-GAVTEETDVIKLDLLDLNRRGFLTINSQPAIDGMPSSHP 429
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG GYVYQKAYLE
Sbjct: 430 VYGWGPKNGYVYQKAYLE 447
[113][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 114 bits (286), Expect = 3e-24
Identities = 57/138 (41%), Positives = 82/138 (59%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR KSY++RT+ W++FP GRWGDSRS ++G L + ++ +Q+W P + D
Sbjct: 327 NRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGTNEQN-RQKWGEPT-CIRD 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
I F ++ PWSE + E +I + L+ +N +G +T+NSQP+VN +S P
Sbjct: 385 IANLFVRYLKKEIEYLPWSEAP-VAEEADLIKDYLLDLNKRGLITVNSQPAVNGVKSTHP 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG GYVYQKAYLE
Sbjct: 444 VHGWGPSKGYVYQKAYLE 461
[114][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6H337_AJECH
Length = 524
Score = 114 bits (285), Expect = 3e-24
Identities = 57/138 (41%), Positives = 85/138 (61%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
+R +SY++RT+ W+++P GRW DSRS ++G L + ++ ++ W P KS+++
Sbjct: 218 HRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYGIGLKGTNEQNIKL-WGEP-KSLKE 275
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ E F GNL PWSE + ET ++ L+ +N +GFLTINSQP+++ S P
Sbjct: 276 LSEIFVRFLNGNLDRLPWSE-GAVTEETDVLKLDLLDLNRRGFLTINSQPAIDGMPSSHP 334
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG GYVYQKAYLE
Sbjct: 335 VYGWGPKNGYVYQKAYLE 352
[115][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 114 bits (285), Expect = 3e-24
Identities = 58/138 (42%), Positives = 85/138 (61%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR SYI+RT W+++P GRW D+RS ++G L+ + ++ ++ W P KS++D
Sbjct: 328 NRNASYIARTADWDEYPNGRWTDARSPAFGELNAYGVRLKGTNEQNIKL-WGAP-KSIKD 385
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ + F G L+ PWS+ + ET I +L+ +N +GFLTINSQP+VN +S P
Sbjct: 386 LSDIFLRYLNGKLERLPWSD-SSVTLETSDIQNELLDLNKRGFLTINSQPAVNGVKSTDP 444
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG G+VYQKAYLE
Sbjct: 445 VHGWGPRNGFVYQKAYLE 462
[116][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 114 bits (285), Expect = 3e-24
Identities = 60/138 (43%), Positives = 78/138 (56%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR SYI+RT+ W++FP GRW DSRS ++G L + ++ ++ W P KS+ D
Sbjct: 327 NRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDSYGIGLKGTNEQNIKL-WGEP-KSLRD 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ F G L PWS+ + E I LI +N KG TINSQP+VN +S P
Sbjct: 385 LTHIFVNFLEGKLARLPWSDTP-ITTEANAIKTSLIDLNQKGLFTINSQPAVNGVKSSHP 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG GYVYQKAYLE
Sbjct: 444 VYGWGPKNGYVYQKAYLE 461
[117][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 114 bits (284), Expect = 4e-24
Identities = 57/138 (41%), Positives = 85/138 (61%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
+R +SY++RT+ W+++P GRW DSRS ++G L + ++ ++ W P KS+++
Sbjct: 327 HRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYGVGLKGTNEQNIKL-WGEP-KSLKE 384
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ E F GNL PWSE + ET ++ L+ +N +GFLTINSQP+++ S P
Sbjct: 385 LSEIFVRFLNGNLDRLPWSE-GAVTEETDVLKLDLLDLNRRGFLTINSQPAIDGMPSSHP 443
Query: 426 TVGWGGPVGYVYQKAYLE 479
GWG GYVYQKAYLE
Sbjct: 444 VYGWGPKNGYVYQKAYLE 461
[118][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 113 bits (283), Expect = 6e-24
Identities = 56/139 (40%), Positives = 83/139 (59%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR SYISRT GW++FP GRWGDSRS ++G + R K+ + W P +++ D
Sbjct: 333 NRKYSYISRTSGWDEFPNGRWGDSRSPAFGDIDLSASELLRQSPKRAYELWGCP-QTLND 391
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ + +K+ PWS+ + +T ++ + LI +N KG T+NSQP+++A RS+
Sbjct: 392 LSDIIVSYLNNEVKALPWSD-GPIGEDTTVLKDALIALNRKGLFTLNSQPALSAVRSNDK 450
Query: 426 TVGWGGPVGYVYQKAYLEF 482
GWG G+VYQK YLEF
Sbjct: 451 LYGWGPKNGFVYQKQYLEF 469
[119][TOP]
>UniRef100_Q7S2B6 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S2B6_NEUCR
Length = 681
Score = 112 bits (279), Expect = 2e-23
Identities = 59/134 (44%), Positives = 82/134 (61%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS +YG + + S + LQ W P K+ EDI + F
Sbjct: 406 LGREATWDDFPNGRWGDARSPAYGQIDGYGVSLHVTVPQALQL-WGSP-KTTEDINKIFI 463
Query: 264 ELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGG 443
G L + PWSE +G ET I + LI++NS+G+ ++ SQP+VN RSD T GWG
Sbjct: 464 RHLKGELSAIPWSE-EGFNDETEAIRDNLIELNSRGWWSLASQPAVNGLRSDDGTFGWGP 522
Query: 444 PVGYVYQKAYLEFF 485
G+V+QKA++EFF
Sbjct: 523 ENGFVFQKAFVEFF 536
[120][TOP]
>UniRef100_C9S8T9 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S8T9_9PEZI
Length = 670
Score = 111 bits (277), Expect = 3e-23
Identities = 59/134 (44%), Positives = 83/134 (61%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS +YG + + S + + ++ W P SV DI F
Sbjct: 408 LGREATWDDFPNGRWGDARSPAYGEIDGYGVSLHMSVTQAVRL-WGHPKSSV-DISTLFI 465
Query: 264 ELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGG 443
+ G L + PWSE +GL PET II EQLI++N++G+ T+ SQP+VN S T GWG
Sbjct: 466 KHIRGELSAIPWSE-EGLSPETNIIQEQLIELNTRGWWTVASQPAVNGVPSRDATFGWGP 524
Query: 444 PVGYVYQKAYLEFF 485
G+V+QKA++E F
Sbjct: 525 SHGFVFQKAFVELF 538
[121][TOP]
>UniRef100_Q6FNS2 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FNS2_CANGA
Length = 645
Score = 110 bits (276), Expect = 4e-23
Identities = 56/140 (40%), Positives = 86/140 (61%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
+R + R W++FP GR+GDSRS +YG + + S + +K+ + W P S+ D
Sbjct: 386 SRGSGVLGRDATWDEFPNGRFGDSRSPAYGEIDGYGPSL-KVSNKRAYELWGSPT-SIRD 443
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
++ F + G+++S PW +L GL PET +I E+LI++N +G+LT+ SQP NA S
Sbjct: 444 LKAVFVKYLEGSIQSLPWCDL-GLSPETALIQEELIQLNYRGYLTLASQPCTNASSSTDK 502
Query: 426 TVGWGGPVGYVYQKAYLEFF 485
GWG G+VYQKA++E F
Sbjct: 503 IFGWGPSKGHVYQKAFIEMF 522
[122][TOP]
>UniRef100_A7TRT4 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TRT4_VANPO
Length = 645
Score = 110 bits (276), Expect = 4e-23
Identities = 58/134 (43%), Positives = 82/134 (61%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W++FP GR+GDSRS +YG + D + KK W P KSV D++ F
Sbjct: 392 LGRNATWDEFPNGRFGDSRSPAYGEI-DGYGPTLKVGIKKAYDLWGTP-KSVIDLKSVFI 449
Query: 264 ELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGG 443
+ G++ + PW +L GL PET +I E+LI++N +G+LT+ SQP+ NA S GWG
Sbjct: 450 KYLEGSISALPWCDL-GLSPETALIQEELIQLNQRGYLTLASQPATNASPSTDKIFGWGP 508
Query: 444 PVGYVYQKAYLEFF 485
GYVYQKA++E F
Sbjct: 509 KNGYVYQKAFVEMF 522
[123][TOP]
>UniRef100_Q752W6 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q752W6_ASHGO
Length = 635
Score = 109 bits (273), Expect = 8e-23
Identities = 57/134 (42%), Positives = 83/134 (61%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W++FP GR+GDSRS +YG + + S + +KK Q W P ++ DI+ F
Sbjct: 383 LGRDATWDEFPNGRFGDSRSPAYGEIDGYGPSL-KVSNKKAYQIWGYP-STLNDIKSLFI 440
Query: 264 ELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGG 443
G++++ PW +L GL PET +I E+LI +N +GFLT+ SQP+ N+ S GWG
Sbjct: 441 GYLEGSIEALPWCDL-GLSPETALIQEELIGLNQRGFLTLASQPATNSTPSADKIFGWGP 499
Query: 444 PVGYVYQKAYLEFF 485
P G VYQKA++E F
Sbjct: 500 PGGVVYQKAFVELF 513
[124][TOP]
>UniRef100_B2WHR5 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WHR5_PYRTR
Length = 653
Score = 109 bits (273), Expect = 8e-23
Identities = 57/138 (41%), Positives = 84/138 (60%), Gaps = 4/138 (2%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDH----QFSRPRARDKKLQQEWVVPLKSVEDIQ 251
+ R W+DFP GRWGD+RS ++G + + S P+A + W P++ +DI
Sbjct: 404 LGREATWDDFPNGRWGDARSPAFGEIDGYGPTLHVSTPQAL-----KLWGYPVEK-KDIS 457
Query: 252 EKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTV 431
F+ G+L++ PWSE GL PET I+ QL+ +N+KG+ T+ SQP+VN +S P
Sbjct: 458 TLFRRHIEGDLEAIPWSE-QGLSPETSTISAQLLALNAKGWWTVASQPAVNGVKSTDPIF 516
Query: 432 GWGGPVGYVYQKAYLEFF 485
GWG GYV+QK ++EFF
Sbjct: 517 GWGPKNGYVFQKPFVEFF 534
[125][TOP]
>UniRef100_Q0UB79 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UB79_PHANO
Length = 543
Score = 109 bits (272), Expect = 1e-22
Identities = 56/134 (41%), Positives = 83/134 (61%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS ++G + + + + + L+ W P+ +DI F+
Sbjct: 294 LGREATWDDFPNGRWGDARSPAFGEIDGYGPTLHVSTTQALKL-WGHPVDK-QDISALFR 351
Query: 264 ELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGG 443
+ G L++ PWSE GL PET I +QL+ +N+KG+ T+ SQP+VN RS P GWG
Sbjct: 352 KHLEGELEALPWSE-QGLSPETSTIAKQLLALNAKGWWTVASQPAVNGVRSTDPVFGWGP 410
Query: 444 PVGYVYQKAYLEFF 485
GYV+QK ++EFF
Sbjct: 411 KNGYVFQKPFVEFF 424
[126][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 108 bits (269), Expect = 2e-22
Identities = 58/145 (40%), Positives = 81/145 (55%), Gaps = 4/145 (2%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQE----WVVPLK 233
NR KS+I RT W++FP GR G+ SA+YG + S + +K+ + W +
Sbjct: 305 NRQKSFIQRTSSWDEFPNGRLGNQASAAYGDFELNFRSYSKETQEKVAADRRRMWGDHVP 364
Query: 234 SVEDIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAER 413
+ + ++ F + G +K PW + ET I +QLI++N LTINSQP VN
Sbjct: 365 NGDHVRRVFTDFIKGEVKRLPWCTEPPTE-ETLFIQKQLIRLNQCNMLTINSQPRVNGAL 423
Query: 414 SDSPTVGWGGPVGYVYQKAYLEFFC 488
S P VGWG G+VYQKAY+EFFC
Sbjct: 424 STDPYVGWGPAGGFVYQKAYVEFFC 448
[127][TOP]
>UniRef100_C5DPF1 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5DPF1_ZYGRC
Length = 650
Score = 107 bits (268), Expect = 3e-22
Identities = 54/134 (40%), Positives = 84/134 (62%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W++FP GR+GD+RS ++G + D + +KK + W P K+++D+Q F
Sbjct: 396 LGRDATWDEFPNGRFGDTRSPAFGEI-DGYGPTLKVSNKKAYELWGQP-KTIQDLQIIFI 453
Query: 264 ELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGG 443
+ G++ + PW +L GL PET +I E+LI++N +GFLT+ SQP+ N S + GWG
Sbjct: 454 KYLEGSIDALPWCDL-GLSPETALIQEELIQLNERGFLTLASQPATNGSPSTNKIFGWGP 512
Query: 444 PVGYVYQKAYLEFF 485
G VYQKA++E F
Sbjct: 513 AYGVVYQKAFIEMF 526
[128][TOP]
>UniRef100_A7QB32 Chromosome chr5 scaffold_72, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7QB32_VITVI
Length = 170
Score = 107 bits (267), Expect = 4e-22
Identities = 49/79 (62%), Positives = 62/79 (78%)
Frame = +3
Query: 135 SRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFKELCLGNLKSSPWSELDG 314
S + SYGAL D+QF RP A DKKLQ+EWVVPLKSVEDIQ++F + C G LK+ PW E +G
Sbjct: 3 SCNPSYGALIDYQFMRPHACDKKLQEEWVVPLKSVEDIQKRFMKFCRGKLKNGPWKEFEG 62
Query: 315 LQPETRIINEQLIKVNSKG 371
LQP+T+II+E + +N KG
Sbjct: 63 LQPDTKIIDEPIGNINLKG 81
[129][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1CZX0_NEOFI
Length = 716
Score = 107 bits (267), Expect = 4e-22
Identities = 60/143 (41%), Positives = 84/143 (58%), Gaps = 8/143 (5%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS ++G + + S ++ W P+ S EDI F+
Sbjct: 428 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSL-HVSGAVARRIWGYPV-SREDISALFR 485
Query: 264 ELCLGNLKSSPWSE------LDGLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERSDS 422
G+L PWSE GL ET +I +L+K ++SKG+ T+ SQP+VN RSD
Sbjct: 486 RHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLIDSKGWWTLASQPAVNGVRSDD 545
Query: 423 PTVGWGGP-VGYVYQKAYLEFFC 488
PT GWG P G+V+QK ++EFFC
Sbjct: 546 PTFGWGPPGEGFVFQKPFVEFFC 568
[130][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 105 bits (263), Expect = 1e-21
Identities = 59/143 (41%), Positives = 83/143 (58%), Gaps = 8/143 (5%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS ++G + + S ++ W P+ S EDI F+
Sbjct: 401 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSL-HVSGAVARRIWGYPV-SREDISALFR 458
Query: 264 ELCLGNLKSSPWSE------LDGLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERSDS 422
G+L PWSE GL ET +I +L+K ++ KG+ T+ SQP+VN RSD
Sbjct: 459 HHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRSDD 518
Query: 423 PTVGWGGP-VGYVYQKAYLEFFC 488
PT GWG P G+V+QK ++EFFC
Sbjct: 519 PTFGWGPPGEGFVFQKPFVEFFC 541
[131][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 105 bits (263), Expect = 1e-21
Identities = 59/143 (41%), Positives = 83/143 (58%), Gaps = 8/143 (5%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS ++G + + S ++ W P+ S EDI F+
Sbjct: 401 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSL-HVSGAVARRIWGYPV-SREDISALFR 458
Query: 264 ELCLGNLKSSPWSE------LDGLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERSDS 422
G+L PWSE GL ET +I +L+K ++ KG+ T+ SQP+VN RSD
Sbjct: 459 RHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRSDD 518
Query: 423 PTVGWGGP-VGYVYQKAYLEFFC 488
PT GWG P G+V+QK ++EFFC
Sbjct: 519 PTFGWGPPGEGFVFQKPFVEFFC 541
[132][TOP]
>UniRef100_C7GU28 Met12p n=2 Tax=Saccharomyces cerevisiae RepID=C7GU28_YEAS2
Length = 657
Score = 105 bits (262), Expect = 2e-21
Identities = 54/134 (40%), Positives = 85/134 (63%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W++FP GR+GDSRS +YG + + S ++ K L+ W +P K++ D+++ F
Sbjct: 402 LGRDATWDEFPNGRFGDSRSPAYGEIDGYGPSIKVSKSKALEL-WGIP-KTIGDLKDIFI 459
Query: 264 ELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGG 443
+ G+ + PWS+L GL ET +I E+LI++N +G+LT+ SQP+ NA S GWG
Sbjct: 460 KYLEGSTDAIPWSDL-GLSAETALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGP 518
Query: 444 PVGYVYQKAYLEFF 485
G +YQKA++E F
Sbjct: 519 AKGRLYQKAFVEMF 532
[133][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 105 bits (262), Expect = 2e-21
Identities = 60/142 (42%), Positives = 82/142 (57%), Gaps = 7/142 (4%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS ++G + + S + ++ W P S EDI F+
Sbjct: 367 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSL-HVTARVARKLWGTP-TSREDISNIFR 424
Query: 264 ELCLGNLKSSPWS-----ELDGLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERSDSP 425
L G L + PWS E GL PET I +L+K V +G+ T+ SQPSVN R+D P
Sbjct: 425 RLLSGELHAVPWSEGGAGEEGGLNPETATIRTELLKLVEGRGWWTLASQPSVNGVRNDHP 484
Query: 426 TVGWG-GPVGYVYQKAYLEFFC 488
GWG G+V+QKA++EFFC
Sbjct: 485 IFGWGPRGEGFVFQKAFVEFFC 506
[134][TOP]
>UniRef100_B5VTD9 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VTD9_YEAS6
Length = 657
Score = 105 bits (262), Expect = 2e-21
Identities = 54/134 (40%), Positives = 85/134 (63%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W++FP GR+GDSRS +YG + + S ++ K L+ W +P K++ D+++ F
Sbjct: 402 LGRDATWDEFPNGRFGDSRSPAYGEIDGYGPSIKVSKSKALEL-WGIP-KTIGDLKDIFI 459
Query: 264 ELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGG 443
+ G+ + PWS+L GL ET +I E+LI++N +G+LT+ SQP+ NA S GWG
Sbjct: 460 KYLEGSTDAIPWSDL-GLSAETALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGP 518
Query: 444 PVGYVYQKAYLEFF 485
G +YQKA++E F
Sbjct: 519 AKGRLYQKAFVEMF 532
[135][TOP]
>UniRef100_B3LL40 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LL40_YEAS1
Length = 657
Score = 105 bits (262), Expect = 2e-21
Identities = 54/134 (40%), Positives = 85/134 (63%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W++FP GR+GDSRS +YG + + S ++ K L+ W +P K++ D+++ F
Sbjct: 402 LGRDATWDEFPNGRFGDSRSPAYGEIDGYGPSIKVSKSKALEL-WGIP-KTIGDLKDIFI 459
Query: 264 ELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGG 443
+ G+ + PWS+L GL ET +I E+LI++N +G+LT+ SQP+ NA S GWG
Sbjct: 460 KYLEGSTDAIPWSDL-GLSAETALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGP 518
Query: 444 PVGYVYQKAYLEFF 485
G +YQKA++E F
Sbjct: 519 AKGRLYQKAFVEMF 532
[136][TOP]
>UniRef100_P46151 Methylenetetrahydrofolate reductase 1 n=1 Tax=Saccharomyces
cerevisiae RepID=MTHR1_YEAST
Length = 657
Score = 105 bits (262), Expect = 2e-21
Identities = 54/134 (40%), Positives = 85/134 (63%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W++FP GR+GDSRS +YG + + S ++ K L+ W +P K++ D+++ F
Sbjct: 402 LGRDATWDEFPNGRFGDSRSPAYGEIDGYGPSIKVSKSKALEL-WGIP-KTIGDLKDIFI 459
Query: 264 ELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGG 443
+ G+ + PWS+L GL ET +I E+LI++N +G+LT+ SQP+ NA S GWG
Sbjct: 460 KYLEGSTDAIPWSDL-GLSAETALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGP 518
Query: 444 PVGYVYQKAYLEFF 485
G +YQKA++E F
Sbjct: 519 AKGRLYQKAFVEMF 532
[137][TOP]
>UniRef100_C4R2L4 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2L4_PICPG
Length = 596
Score = 105 bits (261), Expect = 2e-21
Identities = 55/128 (42%), Positives = 77/128 (60%)
Frame = +3
Query: 102 WEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFKELCLGN 281
W+DFP GR+GDSRS +YG + + S + + + W P+ ++DI + F
Sbjct: 349 WDDFPNGRYGDSRSPAYGEIDGYGPSL-KVSSSRAYKLWGYPV-DLDDITKIFIAYLSNR 406
Query: 282 LKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGGPVGYVY 461
+ + PWSEL GL PET +I E+LI++N K TI+SQPS N +S GWG GYVY
Sbjct: 407 ITALPWSEL-GLNPETGLIQEELIQLNEKHMFTISSQPSANGVKSTDKLFGWGPSEGYVY 465
Query: 462 QKAYLEFF 485
QKA++E F
Sbjct: 466 QKAFVEVF 473
[138][TOP]
>UniRef100_C5DIA7 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5DIA7_LACTC
Length = 660
Score = 104 bits (259), Expect = 3e-21
Identities = 53/128 (41%), Positives = 81/128 (63%)
Frame = +3
Query: 102 WEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFKELCLGN 281
W++F GR+GDSRS ++G + + S + KK + W P S +DI+ F G+
Sbjct: 414 WDEFTNGRFGDSRSPAFGEIDGYGPSL-KVSSKKAYEIWGQP-SSTDDIKTLFIRYLEGS 471
Query: 282 LKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGGPVGYVY 461
L++ PWS+L GL ET +I E+LI++N +G+L++ SQP+ N+ S GWG P GYVY
Sbjct: 472 LEALPWSDL-GLSAETALIQEELIQLNERGYLSLASQPATNSTPSTDKIFGWGPPGGYVY 530
Query: 462 QKAYLEFF 485
QK+++E F
Sbjct: 531 QKSFVEMF 538
[139][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 103 bits (258), Expect = 5e-21
Identities = 61/140 (43%), Positives = 78/140 (55%), Gaps = 2/140 (1%)
Frame = +3
Query: 69 RPKSYISRTKGW--EDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
RP SY++RT W ++FP GR+GDS S +YG L S R KK + W P ++++
Sbjct: 339 RPYSYVARTSLWNEDEFPNGRFGDSSSPAYGDLDLCGHSLIRQSVKKSIELWSTP-QTLD 397
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
D+ G LK PWS++ L E I + LI +N TINSQP VN + S
Sbjct: 398 DMSNLVTSYLEGKLKCLPWSDVP-LNHEVDDILKHLIDLNKHHIFTINSQPKVNGKPSTD 456
Query: 423 PTVGWGGPVGYVYQKAYLEF 482
P VGWG GYVYQK YLEF
Sbjct: 457 PVVGWGPTKGYVYQKEYLEF 476
[140][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 103 bits (258), Expect = 5e-21
Identities = 61/140 (43%), Positives = 78/140 (55%), Gaps = 2/140 (1%)
Frame = +3
Query: 69 RPKSYISRTKGW--EDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
RP SY++RT W ++FP GR+GDS S ++G L S R KK + W P S+E
Sbjct: 336 RPYSYVARTSQWSVDEFPNGRFGDSSSPAFGDLDLCGASLIRQSGKKSLELWSAP-NSME 394
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
DI + G LK PWS+ L E I +L+ +N K +TINSQP +N +S
Sbjct: 395 DIAQLVINYLRGELKYLPWSDTS-LNHEVDDILPELVTLNQKLIITINSQPQLNGVKSSH 453
Query: 423 PTVGWGGPVGYVYQKAYLEF 482
P GWG GYVYQK YLEF
Sbjct: 454 PVHGWGPRDGYVYQKMYLEF 473
[141][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 103 bits (257), Expect = 6e-21
Identities = 58/140 (41%), Positives = 79/140 (56%), Gaps = 2/140 (1%)
Frame = +3
Query: 69 RPKSYISRTKGW--EDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
RP SY++RT W ++FP GR+GDS S ++G L + R KK + W P K++E
Sbjct: 337 RPYSYVARTSQWAMDEFPNGRFGDSSSPAFGDLDLCGSTLIRQSGKKSLELWSTP-KTIE 395
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
D+ + G +K PWS+ L E I + L+ +N K +TINSQP +N RS+
Sbjct: 396 DVSQLVISYLTGQIKCLPWSDTS-LDEEIDPILDHLLDLNRKMIITINSQPQINGIRSNH 454
Query: 423 PTVGWGGPVGYVYQKAYLEF 482
GWG GYVYQK YLEF
Sbjct: 455 KVHGWGPKDGYVYQKQYLEF 474
[142][TOP]
>UniRef100_UPI000023F2EE hypothetical protein FG07127.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023F2EE
Length = 672
Score = 102 bits (255), Expect = 1e-20
Identities = 53/134 (39%), Positives = 83/134 (61%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GR+GD+RS +YG + + S + + ++ W P K+ +DI + F
Sbjct: 409 LGREATWDDFPNGRFGDARSPAYGEIDGYGVSLHMSVTQAVKL-WDYP-KTRQDINDLFV 466
Query: 264 ELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGG 443
+ G L + PWSE + L+ E+ I L+++N KG+ T+ SQP+VN RS T GWG
Sbjct: 467 KHIQGELSAIPWSE-EELRAESSTIKPHLLQLNGKGWWTVASQPAVNGLRSSDATFGWGP 525
Query: 444 PVGYVYQKAYLEFF 485
P G+V+QK+++EFF
Sbjct: 526 PNGFVFQKSFVEFF 539
[143][TOP]
>UniRef100_Q6CR34 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CR34_KLULA
Length = 649
Score = 102 bits (254), Expect = 1e-20
Identities = 53/134 (39%), Positives = 82/134 (61%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W++FP GR+GDSRS +YG + + S + + + W P+ S+EDI+ F
Sbjct: 397 LGRNVTWDEFPNGRFGDSRSPAYGEIDGYGPSL-KVCNSTAYELWDHPV-SLEDIKNIFI 454
Query: 264 ELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGG 443
G++K+ PWS+L GL ET I E+LI++N +G+L++ SQP+ N +S GWG
Sbjct: 455 RYLEGSMKALPWSDL-GLSAETAFIQEELIELNQRGYLSLASQPATNGSQSTDNIFGWGP 513
Query: 444 PVGYVYQKAYLEFF 485
G +YQKA++E F
Sbjct: 514 ANGLIYQKAFVEIF 527
[144][TOP]
>UniRef100_Q6CEM7 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CEM7_YARLI
Length = 625
Score = 102 bits (254), Expect = 1e-20
Identities = 55/136 (40%), Positives = 79/136 (58%), Gaps = 2/136 (1%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDH--QFSRPRARDKKLQQEWVVPLKSVEDIQEK 257
+ R W+DFP GR+GDS S ++G + + P AR +L W P+ D+ +
Sbjct: 373 VGREAVWDDFPNGRFGDSSSPAFGEIDGYGPSIHVPPARALEL---WGYPVDDA-DLSKL 428
Query: 258 FKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGW 437
F + +G L PWS+ L PET +I EQL+++N KG T+ SQP+ NA +SD GW
Sbjct: 429 FADTIVGKLPFMPWSD-QTLSPETMLIQEQLMELNQKGIWTVASQPACNALKSDDNIFGW 487
Query: 438 GGPVGYVYQKAYLEFF 485
G GYV+QK++ EFF
Sbjct: 488 GPKGGYVFQKSFAEFF 503
[145][TOP]
>UniRef100_A1C4Z1 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C4Z1_ASPCL
Length = 690
Score = 102 bits (254), Expect = 1e-20
Identities = 57/143 (39%), Positives = 82/143 (57%), Gaps = 8/143 (5%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS ++G + + S ++ W P+ S +DI F+
Sbjct: 402 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSL-HVSPTVARRVWGYPV-SRDDISTLFR 459
Query: 264 ELCLGNLKSSPWSE------LDGLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERSDS 422
G L PWSE GL ET +I +L+K ++ KG+ T+ SQP+VN RSD+
Sbjct: 460 RHVSGELYIVPWSEGGAEENTSGLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRSDN 519
Query: 423 PTVGWGGP-VGYVYQKAYLEFFC 488
T GWG P G+V+QK ++EFFC
Sbjct: 520 STFGWGPPGEGFVFQKPFVEFFC 542
[146][TOP]
>UniRef100_C8V780 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5AU15] n=2 Tax=Emericella
nidulans RepID=C8V780_EMENI
Length = 684
Score = 101 bits (252), Expect = 2e-20
Identities = 57/143 (39%), Positives = 81/143 (56%), Gaps = 8/143 (5%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS ++G + + S A + W P+ S +DI + F+
Sbjct: 397 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVA-PSVAHRIWGYPV-STDDISKLFR 454
Query: 264 ELCLGNLKSSPWSE------LDGLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERSDS 422
G+L PWSE GL ET I +L+ ++ KG+ T+ SQP+VN RSD
Sbjct: 455 RHVSGDLHMVPWSEGGAEENTSGLNAETETIRPELLALIDKKGWWTLASQPAVNGVRSDD 514
Query: 423 PTVGWGGP-VGYVYQKAYLEFFC 488
P GWG P G+V+QK ++EFFC
Sbjct: 515 PIFGWGPPGEGFVFQKPFVEFFC 537
[147][TOP]
>UniRef100_A7E9M9 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7E9M9_SCLS1
Length = 663
Score = 101 bits (252), Expect = 2e-20
Identities = 54/134 (40%), Positives = 79/134 (58%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS +YG + + S + ++ ++ W P S DI + F
Sbjct: 409 LGREATWDDFPNGRWGDARSPAYGEIDGYGVSLHMSINQAIKL-WGHP-SSRADITDIFI 466
Query: 264 ELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGG 443
G L + PWSE +GL ET I +QL+ +N KG+ T+ SQP+VN +S GWG
Sbjct: 467 RHLEGQLTAIPWSE-EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGVKSTDSIFGWGP 525
Query: 444 PVGYVYQKAYLEFF 485
G+V+QKA++E F
Sbjct: 526 KNGFVFQKAFVELF 539
[148][TOP]
>UniRef100_A6RQJ7 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6RQJ7_BOTFB
Length = 663
Score = 101 bits (252), Expect = 2e-20
Identities = 54/134 (40%), Positives = 79/134 (58%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS +YG + + S + ++ ++ W P S DI + F
Sbjct: 409 LGREATWDDFPNGRWGDARSPAYGEIDGYGVSLHMSINQAIKL-WGHP-SSRADITDIFI 466
Query: 264 ELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGG 443
G L + PWSE +GL ET I +QL+ +N KG+ T+ SQP+VN +S GWG
Sbjct: 467 RHLEGQLTAIPWSE-EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGLKSSDSIFGWGP 525
Query: 444 PVGYVYQKAYLEFF 485
G+V+QKA++E F
Sbjct: 526 KNGFVFQKAFVELF 539
[149][TOP]
>UniRef100_A4RH85 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RH85_MAGGR
Length = 662
Score = 101 bits (252), Expect = 2e-20
Identities = 53/134 (39%), Positives = 79/134 (58%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+D+P GRWGD+RS +YG + + S + + +Q W P +VED+ F
Sbjct: 389 LGREATWDDYPNGRWGDARSPAYGEIDGYGVSLHMSGTQAVQL-WGRPA-TVEDVSNIFM 446
Query: 264 ELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGG 443
G L + PWSE + ET I + L+ +NS+G+ T+ SQP+VN RS+ T GWG
Sbjct: 447 RHLRGALPAIPWSE-EEFNAETETIRDTLLALNSRGWWTVASQPAVNGLRSNDRTFGWGP 505
Query: 444 PVGYVYQKAYLEFF 485
G+V+QKA++E F
Sbjct: 506 QNGFVFQKAFVEMF 519
[150][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 101 bits (251), Expect = 3e-20
Identities = 59/141 (41%), Positives = 77/141 (54%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR KS+I RT W++FP GR G+ SA+YG D + + R+ K+ Q +
Sbjct: 305 NRQKSFIQRTSSWDEFPNGRLGNQASAAYG---DFELNF-RSYSKETQDK---------- 350
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
F + G +K PW + ET I +QLI++N LTINSQP VN S P
Sbjct: 351 ---VFTDFIKGEVKRLPWCTEPPTE-ETLFIQKQLIRLNQCNMLTINSQPRVNGALSTDP 406
Query: 426 TVGWGGPVGYVYQKAYLEFFC 488
VGWG G+VYQKAY+EFFC
Sbjct: 407 YVGWGPAGGFVYQKAYVEFFC 427
[151][TOP]
>UniRef100_Q0CE17 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CE17_ASPTN
Length = 696
Score = 101 bits (251), Expect = 3e-20
Identities = 56/143 (39%), Positives = 79/143 (55%), Gaps = 8/143 (5%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS ++G + + S + W P+ +DI F+
Sbjct: 409 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSL-HVTPSVAHRIWGYPVTR-DDINTLFR 466
Query: 264 ELCLGNLKSSPWSE------LDGLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERSDS 422
G L PWSE GL PET I +L++ ++ KG+ T+ SQP+VN RSD
Sbjct: 467 RHVSGELHMVPWSEGGAEEGSGGLNPETETIRPELLQLIDGKGWWTLASQPAVNGVRSDD 526
Query: 423 PTVGWGGP-VGYVYQKAYLEFFC 488
P GWG P G+V+QK ++EFFC
Sbjct: 527 PIFGWGPPREGFVFQKPFVEFFC 549
[152][TOP]
>UniRef100_C4JM22 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JM22_UNCRE
Length = 709
Score = 101 bits (251), Expect = 3e-20
Identities = 58/143 (40%), Positives = 81/143 (56%), Gaps = 8/143 (5%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS ++G + + S ++ W P S EDI + F+
Sbjct: 405 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSL-HVTANVARRLWGFP-TSREDINQIFR 462
Query: 264 ELCLGNLKSSPWS------ELDGLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERSDS 422
G L + PWS E GL PET I L+ ++ +G+ T+ SQP+VN RSD
Sbjct: 463 RHVSGALHAVPWSEGGAAEESGGLNPETATIRPYLLDLIDKRGWWTLASQPAVNGVRSDD 522
Query: 423 PTVGWGGP-VGYVYQKAYLEFFC 488
T GWG P G+V+QKA++EFFC
Sbjct: 523 TTFGWGPPGEGFVFQKAFVEFFC 545
[153][TOP]
>UniRef100_C7YTQ6 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YTQ6_NECH7
Length = 674
Score = 100 bits (250), Expect = 4e-20
Identities = 53/134 (39%), Positives = 82/134 (61%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GR+GD+RS +YG + + S + + ++ W P K+ +DI + F
Sbjct: 411 LGREATWDDFPNGRFGDARSPAYGEIDGYGVSLHMSITQAVKL-WGHP-KTRQDINDLFV 468
Query: 264 ELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGG 443
+ G L + PWSE + L E+ I L+++N KG+ T+ SQP+VN RS T GWG
Sbjct: 469 KHIQGQLSAIPWSE-EELLAESSTIQPHLLRLNQKGWWTVASQPAVNGLRSSDGTFGWGP 527
Query: 444 PVGYVYQKAYLEFF 485
P G+V+QK+++EFF
Sbjct: 528 PNGFVFQKSFVEFF 541
[154][TOP]
>UniRef100_A2QUJ5 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QUJ5_ASPNC
Length = 699
Score = 100 bits (250), Expect = 4e-20
Identities = 56/143 (39%), Positives = 80/143 (55%), Gaps = 8/143 (5%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS ++G + + S ++ W P+ EDI F+
Sbjct: 410 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSL-HVSAATARRIWGYPVTR-EDISTLFR 467
Query: 264 ELCLGNLKSSPWSE------LDGLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERSDS 422
G L PWSE +GL ET II +L+ ++ KG+ T+ SQP++N RSD
Sbjct: 468 RHVSGELHMVPWSEGGAEEDSNGLNAETAIIQPELLTLIDKKGWWTLASQPAINGVRSDD 527
Query: 423 PTVGWGGP-VGYVYQKAYLEFFC 488
P GWG P G+V+QK ++EFFC
Sbjct: 528 PVFGWGPPGEGFVFQKPFVEFFC 550
[155][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 100 bits (248), Expect = 7e-20
Identities = 58/140 (41%), Positives = 75/140 (53%), Gaps = 2/140 (1%)
Frame = +3
Query: 69 RPKSYISRTKGW--EDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
RP SY++RT W ++FP GR+GDS S ++G L R K + W P S+
Sbjct: 337 RPYSYVARTSQWAVDEFPNGRFGDSSSPAFGDLDLCGSDLIRQSANKCLELWSTPT-SIN 395
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
D+ GNLK PWS++ + E I LI++N +TINSQP VN RS+
Sbjct: 396 DVAFLVINYLNGNLKCLPWSDIT-INDEINPIKAHLIELNQHSIITINSQPQVNGIRSND 454
Query: 423 PTVGWGGPVGYVYQKAYLEF 482
GWG GYVYQK YLEF
Sbjct: 455 KIHGWGPKDGYVYQKQYLEF 474
[156][TOP]
>UniRef100_B5VIK4 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VIK4_YEAS6
Length = 411
Score = 100 bits (248), Expect = 7e-20
Identities = 58/140 (41%), Positives = 75/140 (53%), Gaps = 2/140 (1%)
Frame = +3
Query: 69 RPKSYISRTKGW--EDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
RP SY++RT W ++FP GR+GDS S ++G L R K + W P S+
Sbjct: 148 RPYSYVARTSQWAVDEFPNGRFGDSSSPAFGDLDLCGSDLIRQSANKCLELWSTPT-SIN 206
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
D+ GNLK PWS++ + E I LI++N +TINSQP VN RS+
Sbjct: 207 DVAFLVINYLNGNLKCLPWSDIP-INDEINPIKAHLIELNQHSIITINSQPQVNGIRSND 265
Query: 423 PTVGWGGPVGYVYQKAYLEF 482
GWG GYVYQK YLEF
Sbjct: 266 KIHGWGPKDGYVYQKQYLEF 285
[157][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 100 bits (248), Expect = 7e-20
Identities = 58/140 (41%), Positives = 75/140 (53%), Gaps = 2/140 (1%)
Frame = +3
Query: 69 RPKSYISRTKGW--EDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
RP SY++RT W ++FP GR+GDS S ++G L R K + W P S+
Sbjct: 337 RPYSYVARTSQWAVDEFPNGRFGDSSSPAFGDLDLCGSDLIRQSANKCLELWSTPT-SIN 395
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
D+ GNLK PWS++ + E I LI++N +TINSQP VN RS+
Sbjct: 396 DVAFLVINYLNGNLKCLPWSDIP-INDEINPIKAHLIELNQHSIITINSQPQVNGIRSND 454
Query: 423 PTVGWGGPVGYVYQKAYLEF 482
GWG GYVYQK YLEF
Sbjct: 455 KIHGWGPKDGYVYQKQYLEF 474
[158][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 100 bits (248), Expect = 7e-20
Identities = 58/140 (41%), Positives = 75/140 (53%), Gaps = 2/140 (1%)
Frame = +3
Query: 69 RPKSYISRTKGW--EDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
RP SY++RT W ++FP GR+GDS S ++G L R K + W P S+
Sbjct: 337 RPYSYVARTSQWAVDEFPNGRFGDSSSPAFGDLDLCGSDLIRQSANKCLELWSTPT-SIN 395
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
D+ GNLK PWS++ + E I LI++N +TINSQP VN RS+
Sbjct: 396 DVAFLVINYLNGNLKCLPWSDIP-INDEINPIKAHLIELNQHSIITINSQPQVNGIRSND 454
Query: 423 PTVGWGGPVGYVYQKAYLEF 482
GWG GYVYQK YLEF
Sbjct: 455 KIHGWGPKDGYVYQKQYLEF 474
[159][TOP]
>UniRef100_Q1DT03 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DT03_COCIM
Length = 711
Score = 99.8 bits (247), Expect = 9e-20
Identities = 57/143 (39%), Positives = 80/143 (55%), Gaps = 8/143 (5%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS ++G + + S ++ W P + EDI F+
Sbjct: 407 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSL-HVTANVARRLWGYP-TTREDINNIFR 464
Query: 264 ELCLGNLKSSPWS------ELDGLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERSDS 422
+ G L + PWS E GL PET I L+ + +G+ TI SQP+V+ RSD
Sbjct: 465 QHVSGGLHAVPWSEGGAAEETGGLSPETITIRPYLLSLIEKRGWWTIASQPAVSGVRSDH 524
Query: 423 PTVGWGGP-VGYVYQKAYLEFFC 488
P GWG P G+V+QKA++EFFC
Sbjct: 525 PIFGWGPPGEGFVFQKAFVEFFC 547
[160][TOP]
>UniRef100_B6QFH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QFH8_PENMQ
Length = 710
Score = 99.8 bits (247), Expect = 9e-20
Identities = 58/142 (40%), Positives = 81/142 (57%), Gaps = 7/142 (4%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGDSRS ++G + + S ++ W P+ + EDI F+
Sbjct: 409 LGREATWDDFPNGRWGDSRSPAFGEIDGYGPSL-HVNATVAKELWGFPV-TREDIGTLFR 466
Query: 264 ELCLGNLKSSPWSELD-----GLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERSDSP 425
+ G L PWSE L ET+II QL++ + K + T+ SQP+VN RSD P
Sbjct: 467 KHVSGELYIVPWSEGGAAEDANLNAETQIIKPQLLQIIEKKNWWTLASQPAVNGVRSDHP 526
Query: 426 TVGWGGP-VGYVYQKAYLEFFC 488
GWG P G+V+QKA++EFFC
Sbjct: 527 VFGWGPPGEGFVFQKAFVEFFC 548
[161][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 99.4 bits (246), Expect = 1e-19
Identities = 58/140 (41%), Positives = 79/140 (56%), Gaps = 2/140 (1%)
Frame = +3
Query: 69 RPKSYISRTKGW--EDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
RP SY++RT W ++FP GR+GDS S +YG L + R ++ + W P +++
Sbjct: 338 RPYSYVARTSQWSADEFPNGRFGDSSSPAYGDLDLCGHTVLRQTYQRSLELWSTP-RTLL 396
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
D+ G+LK PWS++ L E + + LI++N LTINSQP VN S
Sbjct: 397 DLAALVISYLKGDLKCLPWSDVP-LHQEADALLDSLIRLNEHLVLTINSQPKVNGAPSAD 455
Query: 423 PTVGWGGPVGYVYQKAYLEF 482
P VGWG GYVYQK YLEF
Sbjct: 456 PIVGWGPANGYVYQKQYLEF 475
[162][TOP]
>UniRef100_Q2UA39 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus oryzae
RepID=Q2UA39_ASPOR
Length = 690
Score = 99.0 bits (245), Expect = 1e-19
Identities = 57/145 (39%), Positives = 80/145 (55%), Gaps = 10/145 (6%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDH--QFSRPRARDKKLQQEWVVPLKSVEDIQEK 257
+ R W+DFP GRWGD+RS ++G + + P A ++ W P+ S EDI
Sbjct: 401 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVPPAVAHRI---WGFPV-SHEDISAL 456
Query: 258 FKELCLGNLKSSPWSE------LDGLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERS 416
F G L PWSE GL ET +I +L++ ++ G+ T+ SQP+VN RS
Sbjct: 457 FHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPELLQLIDGNGWWTLASQPAVNGVRS 516
Query: 417 DSPTVGWGGP-VGYVYQKAYLEFFC 488
D P GWG P G+V+QK ++EFFC
Sbjct: 517 DDPIYGWGPPREGFVFQKPFVEFFC 541
[163][TOP]
>UniRef100_C5P4Q4 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5P4Q4_COCP7
Length = 711
Score = 99.0 bits (245), Expect = 1e-19
Identities = 56/143 (39%), Positives = 80/143 (55%), Gaps = 8/143 (5%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS ++G + + S ++ W P + EDI F+
Sbjct: 407 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSL-HVTANVARRLWGYP-TTREDINNIFR 464
Query: 264 ELCLGNLKSSPWS------ELDGLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERSDS 422
+ G L + PWS E GL PET I L+ + +G+ T+ SQP+V+ RSD
Sbjct: 465 QHVSGGLHAVPWSEGGAAEETGGLSPETITIRPYLLSLIEKRGWWTLASQPAVSGVRSDH 524
Query: 423 PTVGWGGP-VGYVYQKAYLEFFC 488
P GWG P G+V+QKA++EFFC
Sbjct: 525 PIFGWGPPGEGFVFQKAFVEFFC 547
[164][TOP]
>UniRef100_B8NQE8 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus flavus
NRRL3357 RepID=B8NQE8_ASPFN
Length = 738
Score = 99.0 bits (245), Expect = 1e-19
Identities = 57/145 (39%), Positives = 80/145 (55%), Gaps = 10/145 (6%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDH--QFSRPRARDKKLQQEWVVPLKSVEDIQEK 257
+ R W+DFP GRWGD+RS ++G + + P A ++ W P+ S EDI
Sbjct: 449 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVPPAVAHRI---WGFPV-SHEDISAL 504
Query: 258 FKELCLGNLKSSPWSE------LDGLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERS 416
F G L PWSE GL ET +I +L++ ++ G+ T+ SQP+VN RS
Sbjct: 505 FHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPELLQLIDGNGWWTLASQPAVNGVRS 564
Query: 417 DSPTVGWGGP-VGYVYQKAYLEFFC 488
D P GWG P G+V+QK ++EFFC
Sbjct: 565 DDPIYGWGPPREGFVFQKPFVEFFC 589
[165][TOP]
>UniRef100_C1H0K0 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1H0K0_PARBA
Length = 713
Score = 98.6 bits (244), Expect = 2e-19
Identities = 58/143 (40%), Positives = 80/143 (55%), Gaps = 8/143 (5%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS ++G + + S +Q W P S EDI + F
Sbjct: 409 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSL-HVNANVARQLWGYP-TSKEDINKLFH 466
Query: 264 ELCLGNLKSSPWSE------LDGLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERSDS 422
G L PWSE GL ET I E+L++ ++ +G+ T+ SQP+VN RSD
Sbjct: 467 CHVSGELHIVPWSEGGSAEDSGGLNAETATIREELLQLIDGRGWWTLASQPAVNGVRSDH 526
Query: 423 PTVGWG-GPVGYVYQKAYLEFFC 488
P GWG G+V+QKA++EFFC
Sbjct: 527 PIFGWGPRGEGFVFQKAFVEFFC 549
[166][TOP]
>UniRef100_B8MDD4 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8MDD4_TALSN
Length = 713
Score = 98.6 bits (244), Expect = 2e-19
Identities = 58/142 (40%), Positives = 79/142 (55%), Gaps = 7/142 (4%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGDSRS ++G + + S +Q W P+ + EDI F+
Sbjct: 411 LGREATWDDFPNGRWGDSRSPAFGEIDGYGPSL-HVNATVAKQLWGFPV-TREDIGALFR 468
Query: 264 ELCLGNLKSSPWSELD-----GLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERSDSP 425
+ G L PWSE L ET I QL++ + K + T+ SQP+VN RSD P
Sbjct: 469 KHVSGELYIVPWSEGGAAEDANLNAETETIKPQLLQIIEKKNWWTLASQPAVNGVRSDHP 528
Query: 426 TVGWGGP-VGYVYQKAYLEFFC 488
GWG P G+V+QKA++EFFC
Sbjct: 529 VFGWGPPGEGFVFQKAFVEFFC 550
[167][TOP]
>UniRef100_C1GJU2 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1GJU2_PARBD
Length = 712
Score = 98.2 bits (243), Expect = 2e-19
Identities = 58/143 (40%), Positives = 80/143 (55%), Gaps = 8/143 (5%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS ++G + + S +Q W P S EDI + F
Sbjct: 409 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSL-HVNANVARQLWGYP-TSREDINKLFH 466
Query: 264 ELCLGNLKSSPWSE------LDGLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERSDS 422
G L PWSE GL ET I E+L++ ++ +G+ T+ SQP+VN RSD
Sbjct: 467 CHVSGELHIVPWSEGGSAEDSGGLNAETATIREELLQLIDGRGWWTLASQPAVNGVRSDH 526
Query: 423 PTVGWG-GPVGYVYQKAYLEFFC 488
P GWG G+V+QKA++EFFC
Sbjct: 527 PIFGWGPRGEGFVFQKAFVEFFC 549
[168][TOP]
>UniRef100_C0S8C4 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0S8C4_PARBP
Length = 712
Score = 98.2 bits (243), Expect = 2e-19
Identities = 58/143 (40%), Positives = 80/143 (55%), Gaps = 8/143 (5%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS ++G + + S +Q W P S EDI + F
Sbjct: 409 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSL-HVNANVARQLWGYP-TSREDINKLFH 466
Query: 264 ELCLGNLKSSPWSE------LDGLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERSDS 422
G L PWSE GL ET I E+L++ ++ +G+ T+ SQP+VN RSD
Sbjct: 467 CHVSGELHIVPWSEGGSAEDSGGLNAETATIREELLQLIDGRGWWTLASQPAVNGVRSDH 526
Query: 423 PTVGWG-GPVGYVYQKAYLEFFC 488
P GWG G+V+QKA++EFFC
Sbjct: 527 PIFGWGPRGEGFVFQKAFVEFFC 549
[169][TOP]
>UniRef100_C9S7I3 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S7I3_9PEZI
Length = 312
Score = 97.4 bits (241), Expect = 4e-19
Identities = 56/137 (40%), Positives = 78/137 (56%)
Frame = +3
Query: 69 RPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDI 248
R KSYI RT+ W++FP GRWGDSRS ++G L + ++ +++ W P ++V+DI
Sbjct: 51 RNKSYILRTQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGTNEQNIKK-WGEP-QTVQDI 108
Query: 249 QEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPT 428
L+S +E D I E LI +N +G +TINSQP+VN +S
Sbjct: 109 ---------ATLESPLTNEADP-------IREDLIALNKRGIITINSQPAVNGVKSSHAV 152
Query: 429 VGWGGPVGYVYQKAYLE 479
GWG GYVYQK+YLE
Sbjct: 153 HGWGPKNGYVYQKSYLE 169
[170][TOP]
>UniRef100_C5GI01 Methylenetetrahydrofolate reductase n=2 Tax=Ajellomyces
dermatitidis RepID=C5GI01_AJEDR
Length = 713
Score = 97.4 bits (241), Expect = 4e-19
Identities = 55/142 (38%), Positives = 81/142 (57%), Gaps = 7/142 (4%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS ++G + + S ++ W P + EDI F+
Sbjct: 406 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSL-HVTPAVARRLWGYP-TTKEDINTIFQ 463
Query: 264 ELCLGNLKSSPWSE-----LDGLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERSDSP 425
G+L PWSE GL ET I ++L++ +N +G+ T+ SQP+VN R+D P
Sbjct: 464 RHVSGDLHIVPWSEGGTQDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRNDHP 523
Query: 426 TVGWG-GPVGYVYQKAYLEFFC 488
GWG G+V+QKA++EFFC
Sbjct: 524 IFGWGPRGEGFVFQKAFVEFFC 545
[171][TOP]
>UniRef100_UPI00003BE162 hypothetical protein DEHA0F09867g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE162
Length = 642
Score = 96.7 bits (239), Expect = 7e-19
Identities = 50/137 (36%), Positives = 77/137 (56%)
Frame = +3
Query: 75 KSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQE 254
K + + W+DFP GR+GDS S +YG + + + ++ +W P +SV +I +
Sbjct: 377 KGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPTLKIYSPEEAIHKWGAP-ESVNEIIK 435
Query: 255 KFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVG 434
F G + S PW + L PET +I E+L +VN+KG+ ++ SQP+VN S G
Sbjct: 436 VFVSYLSGKIDSLPWVDA-ALSPETALIQEELFEVNNKGWFSLASQPAVNGCLSSDKIFG 494
Query: 435 WGGPVGYVYQKAYLEFF 485
WG G +YQKA++E F
Sbjct: 495 WGPGNGIIYQKAFIEIF 511
[172][TOP]
>UniRef100_Q6BM19 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=Q6BM19_DEBHA
Length = 642
Score = 96.7 bits (239), Expect = 7e-19
Identities = 50/137 (36%), Positives = 77/137 (56%)
Frame = +3
Query: 75 KSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQE 254
K + + W+DFP GR+GDS S +YG + + + ++ +W P +SV +I +
Sbjct: 377 KGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPTLKIYSPEEAIHKWGAP-ESVNEIIK 435
Query: 255 KFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVG 434
F G + S PW + L PET +I E+L +VN+KG+ ++ SQP+VN S G
Sbjct: 436 VFVSYLSGKIDSLPWVDA-ALSPETALIQEELFEVNNKGWFSLASQPAVNGCLSSDKIFG 494
Query: 435 WGGPVGYVYQKAYLEFF 485
WG G +YQKA++E F
Sbjct: 495 WGPGNGIIYQKAFIEIF 511
[173][TOP]
>UniRef100_UPI000151A866 hypothetical protein PGUG_01501 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151A866
Length = 642
Score = 96.3 bits (238), Expect = 9e-19
Identities = 49/137 (35%), Positives = 76/137 (55%)
Frame = +3
Query: 75 KSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQE 254
K + + W+DFP GR+GDS S +YG + + S ++ +W P +S +DI +
Sbjct: 379 KGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPSLKIHSPQEAIAKWGTP-ESTKDISK 437
Query: 255 KFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVG 434
F G + PW + L ET +I E+L ++N KG+ ++ SQPSVN RS G
Sbjct: 438 VFLNYLSGKINILPWVDAP-LSAETALIQEELFELNDKGWFSLASQPSVNGARSSDKIFG 496
Query: 435 WGGPVGYVYQKAYLEFF 485
WG G+V+QK+++E F
Sbjct: 497 WGPSNGFVFQKSFVEIF 513
[174][TOP]
>UniRef100_C6HED8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6HED8_AJECH
Length = 713
Score = 96.3 bits (238), Expect = 9e-19
Identities = 54/142 (38%), Positives = 80/142 (56%), Gaps = 7/142 (4%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS ++G + + S ++ W P + +DI F+
Sbjct: 406 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSL-HVNAAVARRLWGYP-TTKQDINNIFQ 463
Query: 264 ELCLGNLKSSPWSE-----LDGLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERSDSP 425
G L PWSE GL ET I ++L++ +N +G+ T+ SQP+VN R+D P
Sbjct: 464 RHVSGELHLVPWSEGGAQDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRNDHP 523
Query: 426 TVGWG-GPVGYVYQKAYLEFFC 488
GWG G+V+QKA++EFFC
Sbjct: 524 IFGWGPRGEGFVFQKAFVEFFC 545
[175][TOP]
>UniRef100_C0NTN2 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NTN2_AJECG
Length = 713
Score = 96.3 bits (238), Expect = 9e-19
Identities = 54/142 (38%), Positives = 80/142 (56%), Gaps = 7/142 (4%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS ++G + + S ++ W P + +DI F+
Sbjct: 406 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSL-HVNAAVARRLWGYP-TTKQDINNIFQ 463
Query: 264 ELCLGNLKSSPWSE-----LDGLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERSDSP 425
G L PWSE GL ET I ++L++ +N +G+ T+ SQP+VN R+D P
Sbjct: 464 RHVSGELHLVPWSEGGAQDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRNDHP 523
Query: 426 TVGWG-GPVGYVYQKAYLEFFC 488
GWG G+V+QKA++EFFC
Sbjct: 524 IFGWGPRGEGFVFQKAFVEFFC 545
[176][TOP]
>UniRef100_A5DZ35 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DZ35_LODEL
Length = 622
Score = 96.3 bits (238), Expect = 9e-19
Identities = 48/140 (34%), Positives = 80/140 (57%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
+R K + + W+DFP GR+GDS S +YG + + S + +W P ++++
Sbjct: 362 SRGKGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPSLKIHNASEAIAKWGSPT-NIKE 420
Query: 246 IQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSP 425
+ + F + G + PW++ L PET +I E+L ++N KG+ ++ SQP+VN RS+
Sbjct: 421 LGQVFVDYLSGKIDVVPWADTS-LSPETALIQEELFELNQKGWFSVASQPAVNGCRSNDN 479
Query: 426 TVGWGGPVGYVYQKAYLEFF 485
GWG G VYQK+++E F
Sbjct: 480 VFGWGPGNGVVYQKSFVELF 499
[177][TOP]
>UniRef100_A5DE00 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DE00_PICGU
Length = 642
Score = 96.3 bits (238), Expect = 9e-19
Identities = 49/137 (35%), Positives = 76/137 (55%)
Frame = +3
Query: 75 KSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQE 254
K + + W+DFP GR+GDS S +YG + + S ++ +W P +S +DI +
Sbjct: 379 KGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPSLKIHSPQEAIAKWGTP-ESTKDISK 437
Query: 255 KFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVG 434
F G + PW + L ET +I E+L ++N KG+ ++ SQPSVN RS G
Sbjct: 438 VFLNYLSGKINILPWVDAP-LSAETALIQEELFELNDKGWFSLASQPSVNGARSSDKIFG 496
Query: 435 WGGPVGYVYQKAYLEFF 485
WG G+V+QK+++E F
Sbjct: 497 WGPSNGFVFQKSFVEIF 513
[178][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TTE9_VANPO
Length = 612
Score = 95.5 bits (236), Expect = 2e-18
Identities = 56/142 (39%), Positives = 79/142 (55%), Gaps = 3/142 (2%)
Frame = +3
Query: 66 NRPKSYISRTKGW--EDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSV 239
+RP SY++RT W ++FP GR+GDS S ++G L + R ++ + W +P S+
Sbjct: 330 SRPYSYVARTSQWAADEFPNGRFGDSSSPAFGDLDLCGSTLLRQSAQRSLELWAMP-SSI 388
Query: 240 EDIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFL-TINSQPSVNAERS 416
D+ G L+ PWS+ + E +I QLI +N + + TINSQP VN RS
Sbjct: 389 RDVAMLVVAYLQGELRCLPWSDTP-VSSEVDVIRRQLIALNEQQLIVTINSQPQVNGLRS 447
Query: 417 DSPTVGWGGPVGYVYQKAYLEF 482
+ GWG GYVYQK YLEF
Sbjct: 448 NVKGFGWGPSDGYVYQKQYLEF 469
[179][TOP]
>UniRef100_A6QT35 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6QT35_AJECN
Length = 712
Score = 95.5 bits (236), Expect = 2e-18
Identities = 54/142 (38%), Positives = 79/142 (55%), Gaps = 7/142 (4%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS ++G + + S ++ W P + +DI F+
Sbjct: 405 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSL-HVNAAVARRLWGYP-TTKQDINNIFQ 462
Query: 264 ELCLGNLKSSPWSE-----LDGLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERSDSP 425
G L PWSE GL ET I ++L+ +N +G+ T+ SQP+VN R+D P
Sbjct: 463 RHVSGELHLVPWSEGGAQDTGGLNAETATIRDELLHLINGRGWWTLASQPAVNGVRNDHP 522
Query: 426 TVGWG-GPVGYVYQKAYLEFFC 488
GWG G+V+QKA++EFFC
Sbjct: 523 IFGWGPRGEGFVFQKAFVEFFC 544
[180][TOP]
>UniRef100_C5M548 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M548_CANTT
Length = 633
Score = 94.4 bits (233), Expect = 4e-18
Identities = 47/137 (34%), Positives = 78/137 (56%)
Frame = +3
Query: 75 KSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQE 254
K + + W+DFP GR+GDS S +YG + + + + + +W P ++ +D+ +
Sbjct: 373 KGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPTLKIHSPAEAEIKWGSP-ETTKDLAQ 431
Query: 255 KFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVG 434
F + G + PW++ L PET +I E+L ++N KG+ ++ SQP+ NA +S G
Sbjct: 432 IFIDYLSGKIDVIPWAD-QALSPETALIQEELFQLNEKGWFSVASQPAANACKSTDNIFG 490
Query: 435 WGGPVGYVYQKAYLEFF 485
WG G VYQKA++E F
Sbjct: 491 WGPRNGVVYQKAFVELF 507
[181][TOP]
>UniRef100_Q5A5S8 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5A5S8_CANAL
Length = 640
Score = 94.0 bits (232), Expect = 5e-18
Identities = 46/137 (33%), Positives = 76/137 (55%)
Frame = +3
Query: 75 KSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQE 254
K + + W+DFP GR+GDS S +YG + + + + +W P +S+ D+ +
Sbjct: 380 KGALGKDAIWDDFPNGRFGDSNSPAYGEIDGYGPTLKIHTPAEASTKWGTP-ESIADLTQ 438
Query: 255 KFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVG 434
F G + PW++ L PET +I E+L ++N KG+ ++ SQP+VN +S G
Sbjct: 439 VFINYLSGKVDVVPWAD-SSLSPETALIQEELFQLNEKGWFSVASQPAVNGCKSTDNIFG 497
Query: 435 WGGPVGYVYQKAYLEFF 485
WG G +YQK+++E F
Sbjct: 498 WGPRNGIIYQKSFIELF 514
[182][TOP]
>UniRef100_C4YKV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=C4YKV3_CANAL
Length = 640
Score = 94.0 bits (232), Expect = 5e-18
Identities = 46/137 (33%), Positives = 76/137 (55%)
Frame = +3
Query: 75 KSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQE 254
K + + W+DFP GR+GDS S +YG + + + + +W P +S+ D+ +
Sbjct: 380 KGALGKDAIWDDFPNGRFGDSNSPAYGEIDGYGPTLKIHTPAEASTKWGTP-ESIADLTQ 438
Query: 255 KFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVG 434
F G + PW++ L PET +I E+L ++N KG+ ++ SQP+VN +S G
Sbjct: 439 VFINYLSGKVDVVPWAD-SSLSPETALIQEELFQLNEKGWFSVASQPAVNGCKSTDNIFG 497
Query: 435 WGGPVGYVYQKAYLEFF 485
WG G +YQK+++E F
Sbjct: 498 WGPRNGIIYQKSFIELF 514
[183][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 93.6 bits (231), Expect = 6e-18
Identities = 56/140 (40%), Positives = 73/140 (52%), Gaps = 2/140 (1%)
Frame = +3
Query: 69 RPKSYISRTKGW--EDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 242
RP SY++RT W ++FP GR+GDS S ++G L + R ++ + W P K
Sbjct: 335 RPYSYVARTSQWTADEFPNGRFGDSSSPAFGDLDLLGSTSIRQSPQRALELWSTPTK-FS 393
Query: 243 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 422
DI + G LK PW ++ L E QL+ +N LT+NSQP VN S
Sbjct: 394 DIAALVIDYLHGKLKCLPWCDV-ALNHEVDTTMPQLLDLNKHMILTLNSQPRVNGASSAD 452
Query: 423 PTVGWGGPVGYVYQKAYLEF 482
VGWG GYVYQK YLEF
Sbjct: 453 KIVGWGPNNGYVYQKQYLEF 472
[184][TOP]
>UniRef100_B6HK87 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6HK87_PENCW
Length = 691
Score = 93.2 bits (230), Expect = 8e-18
Identities = 52/143 (36%), Positives = 80/143 (55%), Gaps = 8/143 (5%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP GRWGD+RS ++G + + S ++ W P+ S +D+ F+
Sbjct: 400 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSL-HVTANTARRLWGHPVDS-KDMSAIFR 457
Query: 264 ELCLGNLKSSPWSE------LDGLQPETRIINEQLIK-VNSKGFLTINSQPSVNAERSDS 422
G L PWSE +GL ET +I +L+K ++ +G+ T+ SQP+VN +D
Sbjct: 458 RHVSGELHMVPWSEGGAEEDGEGLNAETELIRPELLKLIDGRGWWTLASQPAVNGVHNDH 517
Query: 423 PTVGWGGP-VGYVYQKAYLEFFC 488
P GWG G+V+QK ++EFFC
Sbjct: 518 PIFGWGPQREGFVFQKPFVEFFC 540
[185][TOP]
>UniRef100_A3LW82 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LW82_PICST
Length = 635
Score = 93.2 bits (230), Expect = 8e-18
Identities = 50/137 (36%), Positives = 76/137 (55%)
Frame = +3
Query: 75 KSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQE 254
K + + W+DFP GR+GDS S +YG + + S A ++ +W P +SV DI +
Sbjct: 372 KGALGKEAIWDDFPNGRFGDSNSPAYGEIDGYGPSLKVASPEEAIAKWGSP-ESVGDIAK 430
Query: 255 KFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVG 434
F G + PW++ L ET +I E+L +N +G+ ++ SQP+VN +S G
Sbjct: 431 VFMGYLSGKIDILPWTD-SSLSAETTLIQEELFDLNDRGWFSLASQPAVNGCKSTDRIFG 489
Query: 435 WGGPVGYVYQKAYLEFF 485
WG G VYQKA++E F
Sbjct: 490 WGPKNGIVYQKAFVEIF 506
[186][TOP]
>UniRef100_B9WCV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WCV3_CANDC
Length = 640
Score = 92.4 bits (228), Expect = 1e-17
Identities = 45/137 (32%), Positives = 76/137 (55%)
Frame = +3
Query: 75 KSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQE 254
K + + W+DFP GR+GDS S +YG + + + ++ +W P +S+ D+
Sbjct: 380 KGALGKDAIWDDFPNGRFGDSNSPAYGEIDGYGPTLKIHTPEEASTKWGTP-ESLADLTR 438
Query: 255 KFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVG 434
F G + PW++ L PET +I E+L ++N KG+ ++ SQP++N +S G
Sbjct: 439 VFINYLSGKVDVIPWAD-SSLSPETALIQEELFQLNEKGWFSVASQPAINGCKSTDNIFG 497
Query: 435 WGGPVGYVYQKAYLEFF 485
WG G +YQK+++E F
Sbjct: 498 WGPRNGTIYQKSFIELF 514
[187][TOP]
>UniRef100_C4Y9Q4 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y9Q4_CLAL4
Length = 601
Score = 90.9 bits (224), Expect = 4e-17
Identities = 47/128 (36%), Positives = 74/128 (57%)
Frame = +3
Query: 102 WEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFKELCLGN 281
W+DFP GR+GD+ S +YG + + S + + W P +SV D+ F +
Sbjct: 352 WDDFPNGRFGDASSPAYGEIDGYGPSL-KLEPPEAVAVWGTP-QSVADVSRVFIDYLSAK 409
Query: 282 LKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGGPVGYVY 461
+ S PW + L PET +I EQL ++NS+G T+ SQP+V++ S +GWG G ++
Sbjct: 410 ISSLPWVSTE-LSPETALIQEQLFELNSRGLFTLASQPAVDSCPSSDSILGWGPRNGRIF 468
Query: 462 QKAYLEFF 485
QK+++EFF
Sbjct: 469 QKSFVEFF 476
[188][TOP]
>UniRef100_B6JY06 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6JY06_SCHJY
Length = 626
Score = 85.1 bits (209), Expect = 2e-15
Identities = 48/134 (35%), Positives = 75/134 (55%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+D+ GR+GD RS +YG + + S A ++ L+ W P+ +DI FK
Sbjct: 376 LGREATWDDYTNGRFGDPRSPAYGNIDGYGPSLHFAPEESLKL-WGYPVDE-DDITNIFK 433
Query: 264 ELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGG 443
LG + PW + ++ ET+ I ++L K+ K + T+ SQP+VNA S GWG
Sbjct: 434 RHVLGETTAIPWID-QPVEAETKTIGDKLAKLIEKKWWTVGSQPAVNAAPSSHAIFGWGP 492
Query: 444 PVGYVYQKAYLEFF 485
G+V+QKA++E F
Sbjct: 493 RGGWVFQKAFVEMF 506
[189][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR2_SCHPO
Length = 641
Score = 83.2 bits (204), Expect = 8e-15
Identities = 46/136 (33%), Positives = 74/136 (54%), Gaps = 2/136 (1%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDH--QFSRPRARDKKLQQEWVVPLKSVEDIQEK 257
+ R W+DF GR+GD RS +YG + + P + KL W P+ DI
Sbjct: 389 LGRQANWDDFTNGRFGDPRSPAYGEIDGYGPTLHFPPSEALKL---WGYPVDE-SDITSL 444
Query: 258 FKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGW 437
F++ + ++ + PW + + ++ ET+ I + L+K+N + T+ SQP+VN S P GW
Sbjct: 445 FQKHIMSDISAIPWID-EPVEVETKTIAKYLLKLNGNSWWTVGSQPAVNGAPSADPVFGW 503
Query: 438 GGPVGYVYQKAYLEFF 485
G G V+QKA++E F
Sbjct: 504 GPKGGRVFQKAFVECF 519
[190][TOP]
>UniRef100_Q2HBA5 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2HBA5_CHAGB
Length = 643
Score = 81.6 bits (200), Expect = 2e-14
Identities = 49/134 (36%), Positives = 67/134 (50%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
+ R W+DFP G + +Q W P+ S DI F
Sbjct: 428 LGREATWDDFPNGSL-------------------HVTVAQARQLWGAPV-SPPDISAIFI 467
Query: 264 ELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGG 443
G L++ PWSE + ET I +QL+ +NSKG+ T+ SQP+VN RS PT GWG
Sbjct: 468 RHLRGELQTIPWSE-ESFSAETDKIRDQLVALNSKGWWTLASQPAVNGLRSSDPTFGWGP 526
Query: 444 PVGYVYQKAYLEFF 485
G+V+QKA++EFF
Sbjct: 527 QNGFVFQKAFVEFF 540
[191][TOP]
>UniRef100_A7S359 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
RepID=A7S359_NEMVE
Length = 102
Score = 81.3 bits (199), Expect = 3e-14
Identities = 40/66 (60%), Positives = 47/66 (71%)
Frame = +3
Query: 288 SSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGGPVGYVYQK 467
S PW++ + L ET I E+LI NS G L+INSQPSVNA S P +GWGG GY+YQK
Sbjct: 3 SLPWND-EELALETSFIKEKLIHFNSNGILSINSQPSVNAASSTDPLLGWGGEGGYIYQK 61
Query: 468 AYLEFF 485
AYLEFF
Sbjct: 62 AYLEFF 67
[192][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 78.6 bits (192), Expect = 2e-13
Identities = 49/132 (37%), Positives = 76/132 (57%), Gaps = 4/132 (3%)
Frame = +3
Query: 102 WEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFKELCLGN 281
W++FP GR+ D RS +YG + D S + + +EW VP+ S D+ F +
Sbjct: 380 WDEFPNGRFTDVRSPAYGEI-DGWGSGLKITAAQALKEWGVPV-STSDLSALFTAYLHSD 437
Query: 282 LK--SSPWSELDGLQPETRIINEQLIKVNSKGFL--TINSQPSVNAERSDSPTVGWGGPV 449
K ++P+ +L L PE+ +I L+ +NS T+ SQP+V+A +S+ VGWG
Sbjct: 438 PKHLTTPFCDLP-LSPESHMILPHLLALNSANVQHWTVGSQPAVDAAKSEDEVVGWGPRG 496
Query: 450 GYVYQKAYLEFF 485
GYV+QKA++EFF
Sbjct: 497 GYVFQKAFVEFF 508
[193][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NEV2_COPC7
Length = 617
Score = 78.6 bits (192), Expect = 2e-13
Identities = 47/133 (35%), Positives = 74/133 (55%), Gaps = 4/133 (3%)
Frame = +3
Query: 102 WEDFPQGRWGDSRSASYGALSDHQFSRPR----ARDKKLQQEWVVPLKSVEDIQEKFKEL 269
W+DFP GR+GD +S ++G + + P +R + LQQ W P K+ +D+ F
Sbjct: 363 WDDFPNGRFGDFKSPAFG--NQDPWGGPGGLGISRAEALQQ-WGYP-KTFDDLTRIFLAH 418
Query: 270 CLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGGPV 449
+ +P+S + L PE+ I L ++ +G+ T+ SQP+V+ S T GWG
Sbjct: 419 LHSEIPITPFSPTE-LCPESITILPHLERLTKRGWWTVGSQPAVDGISSSDETFGWGPRA 477
Query: 450 GYVYQKAYLEFFC 488
GYV+QK ++EFFC
Sbjct: 478 GYVFQKGFVEFFC 490
[194][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 74.3 bits (181), Expect = 4e-12
Identities = 48/152 (31%), Positives = 77/152 (50%), Gaps = 11/152 (7%)
Frame = +3
Query: 63 ANRPKSY-ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSV 239
A SY + T W++FP GR+GDSRS ++G + + S + + + W P+ S+
Sbjct: 413 ARTSSSYQVPETSTWDEFPNGRYGDSRSPAFGEMDGYGVSL-KVPPQDALRIWGHPV-SL 470
Query: 240 EDIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVN----------SKGFLTINS 389
DI F + PW + L ET I + L+ +N KG+ ++ S
Sbjct: 471 TDISRIFGFYLEEKISCIPWCDAP-LMNETLQIRDHLLTLNRLAENASQSAGKGWWSVGS 529
Query: 390 QPSVNAERSDSPTVGWGGPVGYVYQKAYLEFF 485
QP+V+ S P VG+G P G+V+QK+++E F
Sbjct: 530 QPAVDGAPSTDPIVGFGPPGGFVFQKSFVELF 561
[195][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 73.6 bits (179), Expect = 7e-12
Identities = 41/129 (31%), Positives = 70/129 (54%)
Frame = +3
Query: 102 WEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFKELCLGN 281
W+DFP GR+GD +S ++G + + + +W P KS++D+ + F
Sbjct: 351 WDDFPNGRFGDFKSPAFG--NQDLWGGSGISGSDVLAQWNNP-KSLDDLTQIFLGHLHAK 407
Query: 282 LKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGGPVGYVY 461
+ ++P+S L E+ +I L ++ + + T+ SQP+V+ S VGWG GYV+
Sbjct: 408 ILTTPFSPTP-LSSESLMILPHLERLTRRSWWTVGSQPAVDGVSSGDKVVGWGPRGGYVF 466
Query: 462 QKAYLEFFC 488
QK ++EFFC
Sbjct: 467 QKGFVEFFC 475
[196][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 72.0 bits (175), Expect = 2e-11
Identities = 44/140 (31%), Positives = 74/140 (52%), Gaps = 6/140 (4%)
Frame = +3
Query: 84 ISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFK 263
IS + W++FP GR+ D+RS ++G + D + + ++ + W P+ +DI F
Sbjct: 329 ISGSVTWDEFPNGRYTDARSPAFGEM-DGYGANLKVPPEEAVRLWGTPVDE-DDISSIFS 386
Query: 264 ELCLGNLKSSPWSELDGLQPETRIINEQLIKVNS------KGFLTINSQPSVNAERSDSP 425
G L PW ++ + ET + L+ +NS K + T+ SQP+V+ S P
Sbjct: 387 RFVDGRLACMPWCDIP-VWDETMQLLPALLHLNSPPSAGGKAWWTVGSQPAVDGCDSTDP 445
Query: 426 TVGWGGPVGYVYQKAYLEFF 485
T G+G GY++QKA++E F
Sbjct: 446 TFGFGPQGGYIFQKAFVELF 465
[197][TOP]
>UniRef100_A6SLU6 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6SLU6_BOTFB
Length = 390
Score = 60.1 bits (144), Expect = 7e-08
Identities = 28/65 (43%), Positives = 43/65 (66%)
Frame = +3
Query: 66 NRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVED 245
NR KSY++RT+ W++FP GRWGDSRS ++G L + + ++ ++ W P KS++D
Sbjct: 327 NRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDAYGIGLKGSNEQNIKL-WGQP-KSIKD 384
Query: 246 IQEKF 260
I E F
Sbjct: 385 IAELF 389