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[1][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
           thaliana RepID=B9DHL6_ARATH
          Length = 402

 Score =  302 bits (773), Expect = 2e-80
 Identities = 144/144 (100%), Positives = 144/144 (100%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG
Sbjct: 259 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 318

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV
Sbjct: 319 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 378

Query: 235 KNSYYLVSLVDNNYINGDIFSVFA 164
           KNSYYLVSLVDNNYINGDIFSVFA
Sbjct: 379 KNSYYLVSLVDNNYINGDIFSVFA 402

[2][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
           RepID=MTHR1_ARATH
          Length = 592

 Score =  302 bits (773), Expect = 2e-80
 Identities = 144/144 (100%), Positives = 144/144 (100%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG
Sbjct: 449 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 508

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV
Sbjct: 509 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 568

Query: 235 KNSYYLVSLVDNNYINGDIFSVFA 164
           KNSYYLVSLVDNNYINGDIFSVFA
Sbjct: 569 KNSYYLVSLVDNNYINGDIFSVFA 592

[3][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
           RepID=MTHR2_ARATH
          Length = 594

 Score =  264 bits (675), Expect = 3e-69
 Identities = 122/144 (84%), Positives = 132/144 (91%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           +SDSP +GWGGP GYVYQKAYLEFFCSK+KLD +VEK KA PSITYMAVNK E WVSNT 
Sbjct: 449 RSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTA 508

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           ++DVNAVTWGVFPAKE+IQPTIVDPASF VWKDEAFE WSRSWANLYPE DPSR LLEEV
Sbjct: 509 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 568

Query: 235 KNSYYLVSLVDNNYINGDIFSVFA 164
           KNSYYLVSLV+N+YINGDIF+VFA
Sbjct: 569 KNSYYLVSLVENDYINGDIFAVFA 592

[4][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
           RepID=B9HG95_POPTR
          Length = 608

 Score =  252 bits (644), Expect = 1e-65
 Identities = 113/144 (78%), Positives = 131/144 (90%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KSDSP++GWGGPGGYVYQKAYLEFFCSK+KL+ LVE+ KAFP +TYMAVN+  +W+SN  
Sbjct: 463 KSDSPSVGWGGPGGYVYQKAYLEFFCSKEKLNALVERCKAFPLVTYMAVNRGGSWISNVA 522

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
            +DVNAVTWGVFPAKE+IQPT+VDP SF VWKDEAFEIWSR WA+LYPE DPSR LLEEV
Sbjct: 523 LTDVNAVTWGVFPAKEIIQPTVVDPTSFSVWKDEAFEIWSRGWASLYPEGDPSRTLLEEV 582

Query: 235 KNSYYLVSLVDNNYINGDIFSVFA 164
           +NSY+LVSLVDN+YI+GDIF+VFA
Sbjct: 583 QNSYFLVSLVDNDYIHGDIFAVFA 606

[5][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
           RepID=B9N8L0_POPTR
          Length = 606

 Score =  249 bits (635), Expect = 2e-64
 Identities = 111/144 (77%), Positives = 130/144 (90%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KSDSP++GWGGPGGYVYQKAYLEFFCSKDKL+ LV+K K+FP +TY+AVNK  +W+SN  
Sbjct: 460 KSDSPSVGWGGPGGYVYQKAYLEFFCSKDKLNALVDKCKSFPFVTYIAVNKGGSWISNVA 519

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
            +DVNAVTWGVFP KE+IQPT+VDP SF VWKDEAFEIWSR WA+LYPE DPSR LLEEV
Sbjct: 520 LTDVNAVTWGVFPGKEIIQPTVVDPTSFSVWKDEAFEIWSRGWASLYPEGDPSRTLLEEV 579

Query: 235 KNSYYLVSLVDNNYINGDIFSVFA 164
           ++SY+LVSLVDN+YI+GDIF+VFA
Sbjct: 580 QSSYFLVSLVDNDYIHGDIFAVFA 603

[6][TOP]
>UniRef100_A9P8D1 Putative uncharacterized protein n=1 Tax=Populus trichocarpa
           RepID=A9P8D1_POPTR
          Length = 224

 Score =  249 bits (635), Expect = 2e-64
 Identities = 111/144 (77%), Positives = 130/144 (90%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KSDSP++GWGGPGGYVYQKAYLEFFCSKDKL+ LV+K K+FP +TY+AVNK  +W+SN  
Sbjct: 79  KSDSPSVGWGGPGGYVYQKAYLEFFCSKDKLNALVDKCKSFPFVTYIAVNKGGSWISNVA 138

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
            +DVNAVTWGVFP KE+IQPT+VDP SF VWKDEAFEIWSR WA+LYPE DPSR LLEEV
Sbjct: 139 LTDVNAVTWGVFPGKEIIQPTVVDPTSFSVWKDEAFEIWSRGWASLYPEGDPSRTLLEEV 198

Query: 235 KNSYYLVSLVDNNYINGDIFSVFA 164
           ++SY+LVSLVDN+YI+GDIF+VFA
Sbjct: 199 QSSYFLVSLVDNDYIHGDIFAVFA 222

[7][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
           RepID=A5ATB7_VITVI
          Length = 594

 Score =  246 bits (627), Expect = 1e-63
 Identities = 109/143 (76%), Positives = 129/143 (90%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KSDS ++GWGGPGGYVYQKAYLEFFCS++KL+ LV+K K  PS+TYMAVNK   W+SN G
Sbjct: 449 KSDSLSVGWGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHPSLTYMAVNKEGTWMSNVG 508

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
             +VNAVTWGVFPA+E+IQPT+VDP+SF VWKDEAFEIWSR WA LYPEDDPSRKLLEEV
Sbjct: 509 PGEVNAVTWGVFPAREIIQPTVVDPSSFMVWKDEAFEIWSRGWALLYPEDDPSRKLLEEV 568

Query: 235 KNSYYLVSLVDNNYINGDIFSVF 167
           +NS++LVSLVDN+YINGD+F++F
Sbjct: 569 QNSHFLVSLVDNDYINGDLFAIF 591

[8][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
           RepID=B9STA4_RICCO
          Length = 609

 Score =  244 bits (624), Expect = 3e-63
 Identities = 109/144 (75%), Positives = 128/144 (88%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KSDSP++GWGGPGGYVYQKAY+EFFCS DKL  L+EK KA P +TYMAVN+    +SN G
Sbjct: 464 KSDSPSVGWGGPGGYVYQKAYIEFFCSTDKLQALLEKCKALPQLTYMAVNRGGTLLSNVG 523

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           ++DVNAVTWGVFP K++IQPT+VDPASF VWKDEAFEIW+R WA+LYPE DPSRKLLEEV
Sbjct: 524 QNDVNAVTWGVFPGKQIIQPTVVDPASFSVWKDEAFEIWTRGWASLYPESDPSRKLLEEV 583

Query: 235 KNSYYLVSLVDNNYINGDIFSVFA 164
           ++SY+LVSLVDN+YI GDIF+VFA
Sbjct: 584 QSSYFLVSLVDNDYIQGDIFAVFA 607

[9][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
           RepID=UPI00019838C7
          Length = 594

 Score =  243 bits (619), Expect = 1e-62
 Identities = 108/143 (75%), Positives = 128/143 (89%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KSDS ++GWGGPGGYVYQKAYLEFFCS++KL+ LV+K K   S+TYMAVNK   W+SN G
Sbjct: 449 KSDSLSVGWGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHTSLTYMAVNKEGTWMSNVG 508

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
             +VNAVTWGVFPA+E+IQPT+VDP+SF VWKDEAFEIWSR WA LYPEDDPSRKLLEEV
Sbjct: 509 PGEVNAVTWGVFPAREIIQPTVVDPSSFMVWKDEAFEIWSRGWALLYPEDDPSRKLLEEV 568

Query: 235 KNSYYLVSLVDNNYINGDIFSVF 167
           +NS++LVSLVDN+YINGD+F++F
Sbjct: 569 QNSHFLVSLVDNDYINGDLFAIF 591

[10][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
           RepID=A7PSQ4_VITVI
          Length = 587

 Score =  243 bits (619), Expect = 1e-62
 Identities = 108/143 (75%), Positives = 128/143 (89%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KSDS ++GWGGPGGYVYQKAYLEFFCS++KL+ LV+K K   S+TYMAVNK   W+SN G
Sbjct: 442 KSDSLSVGWGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHTSLTYMAVNKEGTWMSNVG 501

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
             +VNAVTWGVFPA+E+IQPT+VDP+SF VWKDEAFEIWSR WA LYPEDDPSRKLLEEV
Sbjct: 502 PGEVNAVTWGVFPAREIIQPTVVDPSSFMVWKDEAFEIWSRGWALLYPEDDPSRKLLEEV 561

Query: 235 KNSYYLVSLVDNNYINGDIFSVF 167
           +NS++LVSLVDN+YINGD+F++F
Sbjct: 562 QNSHFLVSLVDNDYINGDLFAIF 584

[11][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
           subsp. patens RepID=A9U4S7_PHYPA
          Length = 592

 Score =  231 bits (588), Expect = 4e-59
 Identities = 102/144 (70%), Positives = 123/144 (85%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KSDSP++GWGGPGGYVYQKAY+EFFCS +KL  ++EK+K  PS+TY+AVN      SN G
Sbjct: 449 KSDSPSVGWGGPGGYVYQKAYVEFFCSPEKLQAVIEKAKTSPSLTYIAVNAKGETKSNVG 508

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
            + VNAVTWGVFPAKEVIQPT+VDP SF VWKDEAF+ W + WA+LYPEDD SRK+L E+
Sbjct: 509 PTSVNAVTWGVFPAKEVIQPTVVDPVSFMVWKDEAFQAWDQEWASLYPEDDASRKILSEI 568

Query: 235 KNSYYLVSLVDNNYINGDIFSVFA 164
           K+SY+LVS+VDN+YINGD+FSVFA
Sbjct: 569 KSSYFLVSMVDNDYINGDLFSVFA 592

[12][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
           RepID=C5WVY7_SORBI
          Length = 593

 Score =  230 bits (587), Expect = 6e-59
 Identities = 104/143 (72%), Positives = 122/143 (85%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KSDSP +GWGGPGGYVYQKAYLEFFC+K+KLD L+EK KAFPS+TY+AVNK     SN  
Sbjct: 449 KSDSPTVGWGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKAFPSLTYIAVNKDGESFSNIA 508

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
            + VNAVTWGVFP KE+IQPT+VDPASF VWKDEAFEIW+R WA L+PE D SR+LLE+V
Sbjct: 509 PNAVNAVTWGVFPGKEIIQPTVVDPASFMVWKDEAFEIWTRGWACLFPEGDSSRELLEKV 568

Query: 235 KNSYYLVSLVDNNYINGDIFSVF 167
           + SYYLVSLVDN+Y+ GD+F+ F
Sbjct: 569 QKSYYLVSLVDNDYVQGDLFAAF 591

[13][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
           RepID=B8LKP0_PICSI
          Length = 594

 Score =  228 bits (581), Expect = 3e-58
 Identities = 103/143 (72%), Positives = 123/143 (86%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KSDSP+IGWGG  GYVYQKAY+EFFCS +KL+ LVEK+K  P +TY+AVNK     +N G
Sbjct: 449 KSDSPSIGWGGAAGYVYQKAYVEFFCSPEKLNELVEKAKNLPFVTYIAVNKKGATAANIG 508

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
            +DVNAVTWGVFPAKEVIQPT+VDP SF VWKDEAF+ W + WA+LYP+ DPSRK+LEEV
Sbjct: 509 PTDVNAVTWGVFPAKEVIQPTVVDPVSFMVWKDEAFQAWEQEWASLYPDGDPSRKILEEV 568

Query: 235 KNSYYLVSLVDNNYINGDIFSVF 167
           +NSYYLVS+VDN+YI+GD+FSVF
Sbjct: 569 QNSYYLVSVVDNDYIHGDLFSVF 591

[14][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
           RepID=A6XMY8_TRIMO
          Length = 582

 Score =  227 bits (579), Expect = 5e-58
 Identities = 102/143 (71%), Positives = 124/143 (86%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS+SP++GWGGPGGYVYQKAY+EFFC+K+KL  L+EKSKAFPS+TY+AVNK    +SN  
Sbjct: 437 KSESPSVGWGGPGGYVYQKAYVEFFCAKEKLGQLIEKSKAFPSLTYIAVNKEGESISNIP 496

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
            + VNAVTWGVFP KE+IQPT+VD ASF VWKDEAFEIWSR WA L+PE D SR+LLE++
Sbjct: 497 ANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRGWACLFPEGDSSRELLEQI 556

Query: 235 KNSYYLVSLVDNNYINGDIFSVF 167
           + SYYLVSLVDN+YI+GD+F+ F
Sbjct: 557 QKSYYLVSLVDNDYISGDLFAAF 579

[15][TOP]
>UniRef100_A6N158 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Oryza sativa
           Indica Group RepID=A6N158_ORYSI
          Length = 237

 Score =  225 bits (573), Expect = 2e-57
 Identities = 101/143 (70%), Positives = 123/143 (86%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           +SDS ++GWGGPGGYVYQKAYLEFFCSK+KLD L+EKSKAFPS+TY+AVNK     SN  
Sbjct: 92  RSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIAVNKDGESFSNIP 151

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
            + VNAVTWGVFP KE++QPT+VD ASF VWKDEAFEIWS+ WA L+PE D SR++L++V
Sbjct: 152 TNAVNAVTWGVFPGKEIVQPTVVDSASFMVWKDEAFEIWSKGWACLFPEGDSSREILDKV 211

Query: 235 KNSYYLVSLVDNNYINGDIFSVF 167
           + SY+LVSLVDN+YINGD+F+ F
Sbjct: 212 QKSYFLVSLVDNDYINGDLFAAF 234

[16][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
           RepID=MTHR_ORYSJ
          Length = 594

 Score =  225 bits (573), Expect = 2e-57
 Identities = 101/143 (70%), Positives = 123/143 (86%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           +SDS ++GWGGPGGYVYQKAYLEFFCSK+KLD L+EKSKAFPS+TY+AVNK     SN  
Sbjct: 449 RSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIAVNKDGESFSNIP 508

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
            + VNAVTWGVFP KE++QPT+VD ASF VWKDEAFEIWS+ WA L+PE D SR++L++V
Sbjct: 509 TNAVNAVTWGVFPGKEIVQPTVVDSASFMVWKDEAFEIWSKGWACLFPEGDSSREILDKV 568

Query: 235 KNSYYLVSLVDNNYINGDIFSVF 167
           + SY+LVSLVDN+YINGD+F+ F
Sbjct: 569 QKSYFLVSLVDNDYINGDLFAAF 591

[17][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
           RepID=MTHR1_MAIZE
          Length = 593

 Score =  224 bits (570), Expect = 5e-57
 Identities = 100/143 (69%), Positives = 120/143 (83%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KSDSP +GWGGPGGYVYQKAYLEFFC+K+KLD L+EK KAFPS+TY+AVNK     SN  
Sbjct: 449 KSDSPTVGWGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKAFPSLTYIAVNKDGETFSNIS 508

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
            + VNAVTWGVFP KE+IQPT+VD ASF VWKDEAFEIW+R W  ++PE D SR+LLE+V
Sbjct: 509 PNAVNAVTWGVFPGKEIIQPTVVDHASFMVWKDEAFEIWTRGWGCMFPEGDSSRELLEKV 568

Query: 235 KNSYYLVSLVDNNYINGDIFSVF 167
           + +YYLVSLVDN+Y+ GD+F+ F
Sbjct: 569 QKTYYLVSLVDNDYVQGDLFAAF 591

[18][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
           subsp. patens RepID=A9RW65_PHYPA
          Length = 594

 Score =  220 bits (561), Expect = 6e-56
 Identities = 98/144 (68%), Positives = 121/144 (84%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KSDSP++GWGGPGGYVYQKAY+EFFCS +KL  ++EK+K+ PS+T++AVN      SN G
Sbjct: 449 KSDSPSVGWGGPGGYVYQKAYVEFFCSPEKLQAVIEKAKSNPSLTFIAVNAKGETQSNIG 508

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
            + VNAVTWGVFPAKEVIQPT+VDP SF VWKDEAF+ W   WA LY E+D SRK+L E+
Sbjct: 509 PNCVNAVTWGVFPAKEVIQPTVVDPVSFMVWKDEAFQTWDHEWAALYSEEDSSRKILSEI 568

Query: 235 KNSYYLVSLVDNNYINGDIFSVFA 164
           K+SY+LVS+VDN+YINGD+F+VFA
Sbjct: 569 KDSYFLVSMVDNDYINGDLFAVFA 592

[19][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
           Group RepID=Q10BJ6_ORYSJ
          Length = 573

 Score =  189 bits (481), Expect = 1e-46
 Identities = 85/120 (70%), Positives = 102/120 (85%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           +SDS ++GWGGPGGYVYQKAYLEFFCSK+KLD L+EKSKAFPS+TY+AVNK     SN  
Sbjct: 449 RSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIAVNKDGESFSNIP 508

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
            + VNAVTWGVFP KE++QPT+VD ASF VWKDEAFEIWS+ WA L+PE D SR++L++V
Sbjct: 509 TNAVNAVTWGVFPGKEIVQPTVVDSASFMVWKDEAFEIWSKGWACLFPEGDSSREILDKV 568

[20][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
           reinhardtii RepID=A8IAY6_CHLRE
          Length = 594

 Score =  167 bits (422), Expect = 8e-40
 Identities = 80/141 (56%), Positives = 96/141 (68%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 413
           SD    GWGGPGGYVY KAY+EFFCS +   TL  K  A PSITY+A   + +   N   
Sbjct: 451 SDDAVHGWGGPGGYVYGKAYVEFFCSPEAWATLRAKLDAAPSITYLATTAAGSPAGNMAP 510

Query: 412 SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
             VNAVTWGVFP KEVIQPT+V   SF VWKDEAFE+W+  W  LY E   +R LL  +K
Sbjct: 511 DAVNAVTWGVFPGKEVIQPTVVCAPSFAVWKDEAFELWTSEWGALYEEGSAARDLLAGIK 570

Query: 232 NSYYLVSLVDNNYINGDIFSV 170
           +S+ LVS+VDN+Y+ GD+F V
Sbjct: 571 DSWVLVSVVDNDYVAGDLFGV 591

[21][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
           RepID=A7S360_NEMVE
          Length = 612

 Score =  159 bits (403), Expect = 1e-37
 Identities = 68/138 (49%), Positives = 97/138 (70%), Gaps = 1/138 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENW-VSNTG 416
           S  P +GWGG GGY+YQKAYLEFF S + +  L+++ K +P + Y  VN  +   ++N  
Sbjct: 438 STDPLLGWGGEGGYIYQKAYLEFFASPEVVYILLQELKNYPQVNYHVVNNHDTVDITNCD 497

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
                AVTWGVFP +E++QPT+VDP SFK+WKDEAF +W + W+ LY ED  SR ++ ++
Sbjct: 498 SQTPVAVTWGVFPGREIVQPTVVDPISFKIWKDEAFSLWEQQWSRLYTEDSKSRAIINKI 557

Query: 235 KNSYYLVSLVDNNYINGD 182
            N+Y LV+LVDN++I G+
Sbjct: 558 MNTYCLVNLVDNDFIKGN 575

[22][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
           neoformans RepID=Q5K8Q9_CRYNE
          Length = 617

 Score =  157 bits (398), Expect = 5e-37
 Identities = 78/144 (54%), Positives = 98/144 (68%), Gaps = 1/144 (0%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           +SD    GWG PGGYVYQKAYLEFF S D L  L+ + +  P ITY AVNK  +  +NT 
Sbjct: 444 RSDDKVHGWGPPGGYVYQKAYLEFFVSPDLLSPLIRRIEKDPRITYYAVNKQGDLRTNTH 503

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
               NAVTWGVFP KE++QPTIV+  SF  WKDEAFE+    WA+LYP + PSRKL+ + 
Sbjct: 504 SESPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFEL-GLQWAHLYPAESPSRKLITDT 562

Query: 235 KNSYYLVSLVDNNYING-DIFSVF 167
            N+ YLV++V N++ +G  IF  F
Sbjct: 563 MNTSYLVNIVANDFRDGMSIFEPF 586

[23][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
           RepID=B3S098_TRIAD
          Length = 633

 Score =  157 bits (397), Expect = 6e-37
 Identities = 72/137 (52%), Positives = 95/137 (69%), Gaps = 1/137 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENW-VSNTG 416
           S     GWGGP GYVYQKAYLEFF S ++  TL+E    FP I Y A++ SE+  VSN+ 
Sbjct: 477 STHEVFGWGGPNGYVYQKAYLEFFISAERFKTLLEVLPNFPMINYHALDLSESINVSNSD 536

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
                AVTWGVFP +E++QPT+VDP SF  WKDEAF +W+  WANLYPE+  SR+++   
Sbjct: 537 HHQPIAVTWGVFPGREILQPTVVDPTSFSYWKDEAFALWTNQWANLYPEESKSRQVITAA 596

Query: 235 KNSYYLVSLVDNNYING 185
             ++ LV++VDN++I G
Sbjct: 597 VRNFVLVNMVDNDFIQG 613

[24][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
           discoideum RepID=Q54X84_DICDI
          Length = 627

 Score =  155 bits (393), Expect = 2e-36
 Identities = 72/136 (52%), Positives = 92/136 (67%)
 Frame = -2

Query: 574 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 395
           GWGG  G VY+KAY+EFF S +    L+E  K  P ITY AVN+  +  S T     NAV
Sbjct: 464 GWGGKNGIVYKKAYIEFFASPENTLKLIEYFKKCPMITYHAVNRKGD--SKTNTKGTNAV 521

Query: 394 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLV 215
           TWG+FP KE+IQPT+VD  SF VWKDEAF +W   W++ Y     SR LL+ + N+YYL+
Sbjct: 522 TWGIFPGKEIIQPTVVDHNSFMVWKDEAFALWETQWSSTYSPSSTSRTLLDSMINNYYLI 581

Query: 214 SLVDNNYINGDIFSVF 167
           ++VDNN+ING+IF  F
Sbjct: 582 NIVDNNFINGNIFQSF 597

[25][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
           RepID=C3XPI2_BRAFL
          Length = 686

 Score =  152 bits (384), Expect = 2e-35
 Identities = 66/139 (47%), Positives = 96/139 (69%), Gaps = 1/139 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVN-KSENWVSNTG 416
           S  P +GWG PGGYV+QKAYLEFF S++ +  L +    +P++ Y  +  + ++  +N  
Sbjct: 482 STDPVVGWGTPGGYVFQKAYLEFFTSRENVQALFKVLPKYPNVNYHIIKFEGDDDYTNCD 541

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           +    AVTWGVFP KE+IQPT+VDP SFK WKDEAF +W+  W  LY ED  SR+L++ +
Sbjct: 542 QQQPIAVTWGVFPGKEIIQPTVVDPVSFKFWKDEAFTLWTEYWGQLYAEDSKSRELIQHI 601

Query: 235 KNSYYLVSLVDNNYINGDI 179
            +++YLV+LVDN++   +I
Sbjct: 602 HDTWYLVNLVDNDFPRDNI 620

[26][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
           RepID=Q4P5K1_USTMA
          Length = 650

 Score =  151 bits (382), Expect = 3e-35
 Identities = 77/144 (53%), Positives = 96/144 (66%), Gaps = 1/144 (0%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           +SD    GWG   GYVYQKAYLEFF S + LD L+ + +A P ITY AVN   +  +NT 
Sbjct: 456 RSDDKVHGWGPKNGYVYQKAYLEFFVSPEDLDALIARIEADPQITYHAVNSQGDMRTNTN 515

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
               NAVTWGVFP  E+IQPTIV+  SF  WKDEA+EI  R+WA +Y    PSRK LE++
Sbjct: 516 SEAPNAVTWGVFPHCEIIQPTIVESISFLAWKDEAYEI-GRNWAKVYEPTSPSRKFLEDM 574

Query: 235 KNSYYLVSLVDNNY-INGDIFSVF 167
            NSY+LV++V N++  N  IF  F
Sbjct: 575 FNSYFLVNVVHNDFKANDSIFEPF 598

[27][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
           RepID=Q7ZWU2_XENLA
          Length = 643

 Score =  149 bits (377), Expect = 1e-34
 Identities = 65/134 (48%), Positives = 91/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSENWVSNTG 416
           S  P +GWG   GYV+QKAYLEFF S + +  L++  K + P + Y  VN     ++N  
Sbjct: 487 STDPIVGWGPSRGYVFQKAYLEFFTSSEMVSALIKVLKRYEPRVNYHIVNVHGQNITNAA 546

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           +   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   WA LY E+ PSR +++ +
Sbjct: 547 DLQPNAVTWGIFPGREIIQPTVVDPVSFVYWKDEAFALWIEQWAKLYEEESPSRMIIQYI 606

Query: 235 KNSYYLVSLVDNNY 194
            ++YYLV+LVDN++
Sbjct: 607 HDNYYLVNLVDNDF 620

[28][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
           isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
          Length = 679

 Score =  148 bits (374), Expect = 3e-34
 Identities = 64/134 (47%), Positives = 91/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYV+QKAYLEFF S++  + L++  K +   + Y  VN     ++N  
Sbjct: 516 SSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAP 575

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           E   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   W  LY E+ PSR +++ +
Sbjct: 576 ELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYI 635

Query: 235 KNSYYLVSLVDNNY 194
            ++Y+LV+LVDN++
Sbjct: 636 HDNYFLVNLVDNDF 649

[29][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
           isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
          Length = 697

 Score =  148 bits (374), Expect = 3e-34
 Identities = 64/134 (47%), Positives = 91/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYV+QKAYLEFF S++  + L++  K +   + Y  VN     ++N  
Sbjct: 534 SSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAP 593

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           E   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   W  LY E+ PSR +++ +
Sbjct: 594 ELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYI 653

Query: 235 KNSYYLVSLVDNNY 194
            ++Y+LV+LVDN++
Sbjct: 654 HDNYFLVNLVDNDF 667

[30][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
           RepID=MTHR_MACFA
          Length = 656

 Score =  148 bits (374), Expect = 3e-34
 Identities = 64/134 (47%), Positives = 91/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYV+QKAYLEFF S++  + L++  K +   + Y  VN     ++N  
Sbjct: 493 SSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAP 552

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           E   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   W  LY E+ PSR +++ +
Sbjct: 553 ELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYI 612

Query: 235 KNSYYLVSLVDNNY 194
            ++Y+LV+LVDN++
Sbjct: 613 HDNYFLVNLVDNDF 626

[31][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
           3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
          Length = 679

 Score =  148 bits (373), Expect = 4e-34
 Identities = 64/134 (47%), Positives = 91/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYV+QKAYLEFF S++  + L++  K +   + Y  VN     ++N  
Sbjct: 516 SSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAP 575

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           E   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   W  LY E+ PSR +++ +
Sbjct: 576 ELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYEEESPSRTIIQYI 635

Query: 235 KNSYYLVSLVDNNY 194
            ++Y+LV+LVDN++
Sbjct: 636 HDNYFLVNLVDNDF 649

[32][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
           4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
          Length = 697

 Score =  148 bits (373), Expect = 4e-34
 Identities = 64/134 (47%), Positives = 91/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYV+QKAYLEFF S++  + L++  K +   + Y  VN     ++N  
Sbjct: 534 SSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAP 593

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           E   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   W  LY E+ PSR +++ +
Sbjct: 594 ELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYEEESPSRTIIQYI 653

Query: 235 KNSYYLVSLVDNNY 194
            ++Y+LV+LVDN++
Sbjct: 654 HDNYFLVNLVDNDF 667

[33][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
           RepID=B0V153_DANRE
          Length = 656

 Score =  148 bits (373), Expect = 4e-34
 Identities = 63/134 (47%), Positives = 91/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSENWVSNTG 416
           S    +GWG  GGYV+QKAYLEFF S + +  L++  K + P + Y  VN     ++N  
Sbjct: 493 SSDAIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYQIVNVQGRNITNAH 552

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           +   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   WA LY ++ PSR +++ +
Sbjct: 553 DMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIQYI 612

Query: 235 KNSYYLVSLVDNNY 194
            ++Y+LV+LVDN++
Sbjct: 613 HDNYFLVNLVDNDF 626

[34][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
           RepID=MTHR_HUMAN
          Length = 656

 Score =  148 bits (373), Expect = 4e-34
 Identities = 64/134 (47%), Positives = 91/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYV+QKAYLEFF S++  + L++  K +   + Y  VN     ++N  
Sbjct: 493 SSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAP 552

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           E   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   W  LY E+ PSR +++ +
Sbjct: 553 ELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYEEESPSRTIIQYI 612

Query: 235 KNSYYLVSLVDNNY 194
            ++Y+LV+LVDN++
Sbjct: 613 HDNYFLVNLVDNDF 626

[35][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
           Tax=Rattus norvegicus RepID=UPI0000DA28B6
          Length = 660

 Score =  147 bits (372), Expect = 5e-34
 Identities = 62/135 (45%), Positives = 92/135 (68%), Gaps = 1/135 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYV+QKAYLEFF S++ ++ L++  K +   + Y  V+     ++N  
Sbjct: 498 SSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAP 557

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           E   NAVTWG+FP +E++QPT+VDP SF  WKDEAF +W   W  LY E+ PSR +++ +
Sbjct: 558 ELQPNAVTWGIFPGREIVQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 617

Query: 235 KNSYYLVSLVDNNYI 191
            ++Y+LV+LVDN ++
Sbjct: 618 HDNYFLVNLVDNEFL 632

[36][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
           RepID=UPI0000DBFF71
          Length = 695

 Score =  147 bits (372), Expect = 5e-34
 Identities = 62/135 (45%), Positives = 92/135 (68%), Gaps = 1/135 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYV+QKAYLEFF S++ ++ L++  K +   + Y  V+     ++N  
Sbjct: 533 SSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAP 592

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           E   NAVTWG+FP +E++QPT+VDP SF  WKDEAF +W   W  LY E+ PSR +++ +
Sbjct: 593 ELQPNAVTWGIFPGREIVQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 652

Query: 235 KNSYYLVSLVDNNYI 191
            ++Y+LV+LVDN ++
Sbjct: 653 HDNYFLVNLVDNEFL 667

[37][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
           tropicalis RepID=A4IIX8_XENTR
          Length = 643

 Score =  147 bits (372), Expect = 5e-34
 Identities = 64/134 (47%), Positives = 91/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSENWVSNTG 416
           S  P +GWG   GYV+QKAYLEFF S + +  L++  K + P + Y  VN     ++N  
Sbjct: 487 STDPIVGWGPSRGYVFQKAYLEFFTSSEMVTALIKVLKRYEPRVNYHIVNVHGQNITNAA 546

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           +   +AVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   WA LY E+ PSR +++ +
Sbjct: 547 DLQPSAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEEESPSRMIIQYI 606

Query: 235 KNSYYLVSLVDNNY 194
            ++YYLV+LVDN++
Sbjct: 607 HDNYYLVNLVDNDF 620

[38][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
           Tax=Equus caballus RepID=UPI000155DDC5
          Length = 655

 Score =  147 bits (371), Expect = 6e-34
 Identities = 63/134 (47%), Positives = 92/134 (68%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYV+QKAYLEFF S++ ++ L++  K +   + Y  V+     ++N  
Sbjct: 492 SSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAP 551

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           E   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   W  LY E+ PSR +++ +
Sbjct: 552 ELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 611

Query: 235 KNSYYLVSLVDNNY 194
            ++Y+LV+LVDN++
Sbjct: 612 HDNYFLVNLVDNDF 625

[39][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
           Tax=Monodelphis domestica RepID=UPI0000F2D0FD
          Length = 642

 Score =  147 bits (371), Expect = 6e-34
 Identities = 64/134 (47%), Positives = 90/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYV+QKAYLEFF S + ++ L++  K +   + Y  VN     ++N  
Sbjct: 487 STDPIVGWGPSGGYVFQKAYLEFFTSSETVEALLQVLKKYELRVNYHIVNVKGENITNAP 546

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           E   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   W  LY E+ PSR +++ +
Sbjct: 547 ELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 606

Query: 235 KNSYYLVSLVDNNY 194
            ++Y+LV+LVDN +
Sbjct: 607 HDNYHLVNLVDNEF 620

[40][TOP]
>UniRef100_Q497H7 Mthfr protein (Fragment) n=2 Tax=Mus musculus RepID=Q497H7_MOUSE
          Length = 166

 Score =  147 bits (371), Expect = 6e-34
 Identities = 63/134 (47%), Positives = 91/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYV+QKAYLEFF S++ ++ L++  K +   + Y  V+     ++N  
Sbjct: 4   SSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAP 63

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           E   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   W  LY E+ PSR +++ +
Sbjct: 64  ELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 123

Query: 235 KNSYYLVSLVDNNY 194
            ++Y+LV+LVDN +
Sbjct: 124 HDNYFLVNLVDNEF 137

[41][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
           RepID=B2KFL4_MOUSE
          Length = 695

 Score =  147 bits (371), Expect = 6e-34
 Identities = 63/134 (47%), Positives = 91/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYV+QKAYLEFF S++ ++ L++  K +   + Y  V+     ++N  
Sbjct: 533 SSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAP 592

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           E   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   W  LY E+ PSR +++ +
Sbjct: 593 ELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 652

Query: 235 KNSYYLVSLVDNNY 194
            ++Y+LV+LVDN +
Sbjct: 653 HDNYFLVNLVDNEF 666

[42][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
           RepID=A2A7F7_MOUSE
          Length = 695

 Score =  147 bits (371), Expect = 6e-34
 Identities = 63/134 (47%), Positives = 91/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYV+QKAYLEFF S++ ++ L++  K +   + Y  V+     ++N  
Sbjct: 533 SSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAP 592

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           E   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   W  LY E+ PSR +++ +
Sbjct: 593 ELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 652

Query: 235 KNSYYLVSLVDNNY 194
            ++Y+LV+LVDN +
Sbjct: 653 HDNYFLVNLVDNEF 666

[43][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
           50983 RepID=C5L500_9ALVE
          Length = 631

 Score =  147 bits (371), Expect = 6e-34
 Identities = 70/145 (48%), Positives = 102/145 (70%), Gaps = 5/145 (3%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE--KSKAFPSITYMAVNKSENWVSNT 419
           S  P +GWG  GG+VYQKAY+EFFC + +L+ L+   +++ + SI+YMAV    + V + 
Sbjct: 424 STDPYVGWGPAGGFVYQKAYVEFFCPEGQLEQLIRGIEAEKYDSISYMAVTADGSKVRSN 483

Query: 418 --GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDD-PSRKL 248
              +  VNAVTWGVFP  E+IQPT+VD  SF  WKDEAF +W+  W ++YPEDD  SR++
Sbjct: 484 IPPQGQVNAVTWGVFPNSEIIQPTVVDVTSFMAWKDEAFALWN-EWMDVYPEDDHQSRQV 542

Query: 247 LEEVKNSYYLVSLVDNNYINGDIFS 173
           L  ++  Y+L ++VDN+++ GD+FS
Sbjct: 543 LNFIRQHYFLCTVVDNDFVAGDLFS 567

[44][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
           50983 RepID=C5K575_9ALVE
          Length = 583

 Score =  147 bits (371), Expect = 6e-34
 Identities = 70/145 (48%), Positives = 102/145 (70%), Gaps = 5/145 (3%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE--KSKAFPSITYMAVNKSENWVSNT 419
           S  P +GWG  GG+VYQKAY+EFFC + +L+ L+   +++ + SI+YMAV    + V + 
Sbjct: 403 STDPYVGWGPAGGFVYQKAYVEFFCPEGQLEQLIRGIEAEKYDSISYMAVTADGSKVRSN 462

Query: 418 --GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDD-PSRKL 248
              +  VNAVTWGVFP  E+IQPT+VD  SF  WKDEAF +W+  W ++YPEDD  SR++
Sbjct: 463 IPPQGQVNAVTWGVFPNSEIIQPTVVDVTSFMAWKDEAFALWN-EWMDVYPEDDHQSRQV 521

Query: 247 LEEVKNSYYLVSLVDNNYINGDIFS 173
           L  ++  Y+L ++VDN+++ GD+FS
Sbjct: 522 LNFIRQHYFLCTVVDNDFVAGDLFS 546

[45][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
           RepID=MTHR_MOUSE
          Length = 654

 Score =  147 bits (371), Expect = 6e-34
 Identities = 63/134 (47%), Positives = 91/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYV+QKAYLEFF S++ ++ L++  K +   + Y  V+     ++N  
Sbjct: 492 SSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAP 551

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           E   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   W  LY E+ PSR +++ +
Sbjct: 552 ELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 611

Query: 235 KNSYYLVSLVDNNY 194
            ++Y+LV+LVDN +
Sbjct: 612 HDNYFLVNLVDNEF 625

[46][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
           (NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
          Length = 651

 Score =  147 bits (370), Expect = 8e-34
 Identities = 65/134 (48%), Positives = 91/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYV+QKAYLEFF S + +  L++  K +   + Y  VN     ++N  
Sbjct: 495 STDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVQGQNITNAP 554

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           +   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   WA LY E+ PSR +++ +
Sbjct: 555 DLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYI 614

Query: 235 KNSYYLVSLVDNNY 194
            ++YYLV+LVDN++
Sbjct: 615 HDNYYLVNLVDNDF 628

[47][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
           taurus RepID=UPI0000614ECA
          Length = 655

 Score =  147 bits (370), Expect = 8e-34
 Identities = 63/134 (47%), Positives = 91/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYV+QKAYLEFF S++ ++ L++  K +   + Y  V+     ++N  
Sbjct: 492 SSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAP 551

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           E   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   W  LY E+ PSR +++ +
Sbjct: 552 ELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 611

Query: 235 KNSYYLVSLVDNNY 194
            ++Y+LV+LVDN +
Sbjct: 612 HDNYFLVNLVDNEF 625

[48][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
           RepID=A7S5W8_NEMVE
          Length = 619

 Score =  147 bits (370), Expect = 8e-34
 Identities = 68/138 (49%), Positives = 91/138 (65%), Gaps = 1/138 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKS-ENWVSNTG 416
           S+ P  GWG PGGYV+QKAYLEFF  ++    L  + K    I +  VN S E+  +N  
Sbjct: 467 SEDPNHGWGKPGGYVFQKAYLEFFAREEIALELYHQLKDGTRINFHLVNSSGESDFTNAN 526

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
               NAVTWGVFP  E++QPT+VDP +F  WKDEAF +W + W  LYPE   SR +++ +
Sbjct: 527 MYSPNAVTWGVFPGSEILQPTVVDPIAFHYWKDEAFGLWKQQWGRLYPEGSRSRDIIDSI 586

Query: 235 KNSYYLVSLVDNNYINGD 182
            +SYYLV+LVDN+Y+ G+
Sbjct: 587 YDSYYLVNLVDNDYVGGN 604

[49][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
           RepID=MTHR_BOVIN
          Length = 655

 Score =  147 bits (370), Expect = 8e-34
 Identities = 63/134 (47%), Positives = 91/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYV+QKAYLEFF S++ ++ L++  K +   + Y  V+     ++N  
Sbjct: 492 SSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAP 551

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           E   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   W  LY E+ PSR +++ +
Sbjct: 552 ELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 611

Query: 235 KNSYYLVSLVDNNY 194
            ++Y+LV+LVDN +
Sbjct: 612 HDNYFLVNLVDNEF 625

[50][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
           RepID=UPI00017B529C
          Length = 660

 Score =  146 bits (368), Expect = 1e-33
 Identities = 63/134 (47%), Positives = 91/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYVYQKAYLEFF S + +  L++  K + P + Y  VN     ++N  
Sbjct: 497 STDPIVGWGPAGGYVYQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGRNLTNAP 556

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           +   NAVTWG+F  +E++QPT+VDP SF  WKDEAF +W   WA LY ++ PSR +++ +
Sbjct: 557 DMQPNAVTWGIFAGREIVQPTVVDPVSFMSWKDEAFALWIEQWAKLYEDESPSRMIIQYI 616

Query: 235 KNSYYLVSLVDNNY 194
            ++Y+LV+LVDN++
Sbjct: 617 HDNYFLVNLVDNDF 630

[51][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
           RepID=UPI0000E814FF
          Length = 508

 Score =  145 bits (367), Expect = 2e-33
 Identities = 65/134 (48%), Positives = 90/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P  GWG  GGYV+QKAYLEFF S + +  L++  K +   + Y  VN     ++N  
Sbjct: 352 STDPIFGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYELRVNYHIVNVKGQNITNAP 411

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           +   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   WA LY E+ PSR +++ +
Sbjct: 412 DLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYI 471

Query: 235 KNSYYLVSLVDNNY 194
            ++YYLV+LVDN++
Sbjct: 472 HDNYYLVNLVDNDF 485

[52][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
            Tax=Canis lupus familiaris RepID=UPI00005A03BF
          Length = 780

 Score =  145 bits (367), Expect = 2e-33
 Identities = 63/134 (47%), Positives = 90/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592  SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
            S  P +GWG  GGYV+QKAYLEFF S++ +  L++  K +   + Y  V+     ++N  
Sbjct: 618  SSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAP 677

Query: 415  ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
            E   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   W  LY E+ PSR +++ +
Sbjct: 678  ELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 737

Query: 235  KNSYYLVSLVDNNY 194
             ++Y+LV+LVDN +
Sbjct: 738  HDNYFLVNLVDNEF 751

[53][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
           lupus familiaris RepID=UPI0000EB3A6F
          Length = 696

 Score =  145 bits (367), Expect = 2e-33
 Identities = 63/134 (47%), Positives = 90/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYV+QKAYLEFF S++ +  L++  K +   + Y  V+     ++N  
Sbjct: 534 SSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAP 593

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           E   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   W  LY E+ PSR +++ +
Sbjct: 594 ELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 653

Query: 235 KNSYYLVSLVDNNY 194
            ++Y+LV+LVDN +
Sbjct: 654 HDNYFLVNLVDNEF 667

[54][TOP]
>UniRef100_UPI0000ECA34F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Gallus
           gallus RepID=UPI0000ECA34F
          Length = 640

 Score =  145 bits (367), Expect = 2e-33
 Identities = 65/134 (48%), Positives = 90/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P  GWG  GGYV+QKAYLEFF S + +  L++  K +   + Y  VN     ++N  
Sbjct: 484 STDPIFGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYELRVNYHIVNVKGQNITNAP 543

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           +   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   WA LY E+ PSR +++ +
Sbjct: 544 DLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYI 603

Query: 235 KNSYYLVSLVDNNY 194
            ++YYLV+LVDN++
Sbjct: 604 HDNYYLVNLVDNDF 617

[55][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
           RepID=Q3UDB2_MOUSE
          Length = 695

 Score =  145 bits (366), Expect = 2e-33
 Identities = 63/134 (47%), Positives = 90/134 (67%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYV+QKAYLEFF S++ ++ L++  K +   + Y  V+     ++N  
Sbjct: 533 SSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAP 592

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           E   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF  W   W  LY E+ PSR +++ +
Sbjct: 593 ELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFAPWIEQWGKLYEEESPSRMIIQYI 652

Query: 235 KNSYYLVSLVDNNY 194
            ++Y+LV+LVDN +
Sbjct: 653 HDNYFLVNLVDNEF 666

[56][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
           Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
          Length = 646

 Score =  144 bits (363), Expect = 5e-33
 Identities = 63/134 (47%), Positives = 89/134 (66%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYV+QKAYLEFF S + +  L++  K +   + Y  VN     ++N  
Sbjct: 490 SADPVVGWGPSGGYVFQKAYLEFFTSSETVAALLKVLKKYELRVNYHIVNVKGENITNAP 549

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           +   NAVTWG+FP +E+IQPT+VDP SF  WKDEAF +W   W  LY E+ PSR +++ +
Sbjct: 550 DMQPNAVTWGIFPGREIIQPTVVDPVSFMSWKDEAFALWIEQWGKLYEEESPSRMIIQYI 609

Query: 235 KNSYYLVSLVDNNY 194
            ++Y+LV+LVDN +
Sbjct: 610 HDNYHLVNLVDNEF 623

[57][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
           Tax=Hydra magnipapillata RepID=UPI00019265CF
          Length = 623

 Score =  143 bits (360), Expect = 1e-32
 Identities = 66/138 (47%), Positives = 87/138 (63%), Gaps = 1/138 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENW-VSNTG 416
           S     GWGG GGY+YQKAYLEFF  K  +D L+E     P + Y  ++    +  +N  
Sbjct: 471 STDERFGWGGAGGYIYQKAYLEFFMHKKNVDFLLEVLNDNPRVNYHIIDSHGCYDKTNAD 530

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
                AVTWGVFP KE+IQPT+VDP SF  WKDEAF +W   W +LY  +  S K+++ +
Sbjct: 531 RYSPIAVTWGVFPGKEIIQPTVVDPISFNFWKDEAFSLWIEKWQSLYEPESFSAKIIQSI 590

Query: 235 KNSYYLVSLVDNNYINGD 182
            N +YLV+LVDN+YI G+
Sbjct: 591 YNDFYLVNLVDNDYIKGN 608

[58][TOP]
>UniRef100_A8Q9P3 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
           7966 RepID=A8Q9P3_MALGO
          Length = 515

 Score =  143 bits (360), Expect = 1e-32
 Identities = 70/134 (52%), Positives = 90/134 (67%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           +SD P  GWG   GYVYQKAYLEFF S  +LD L+ +  A P ITY AVN   +  +NT 
Sbjct: 365 RSDDPVHGWGPKHGYVYQKAYLEFFVSPQQLDELIARFDAHPQITYHAVNAQGDMRTNTT 424

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
               NAVTWG FP  E++QPTIV+  SF  WKDEA+EI  R WA  Y  + P+R+LLE V
Sbjct: 425 SDAPNAVTWGCFPHCEILQPTIVESMSFLAWKDEAYEI-GRRWAAFYEPESPTRRLLEHV 483

Query: 235 KNSYYLVSLVDNNY 194
            ++Y+LV++V N++
Sbjct: 484 FDTYFLVNVVHNDF 497

[59][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
           tricornutum CCAP 1055/1 RepID=B7G287_PHATR
          Length = 634

 Score =  141 bits (356), Expect = 3e-32
 Identities = 64/136 (47%), Positives = 89/136 (65%), Gaps = 1/136 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 413
           S   + GWGGPGGY+YQKAY E FCS + +  LV   K   S+   AVN + N +    E
Sbjct: 480 STHESFGWGGPGGYIYQKAYCECFCSPENMRCLVNMVKQNQSMNVYAVNNAGNCIQEGTE 539

Query: 412 -SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
              V A+TWGVFP +E++QPTI DP  F VW +EAF +W+  W+NLY  D  S  L+E +
Sbjct: 540 LGGVTALTWGVFPNREILQPTIFDPRIFLVWAEEAFSLWTSMWSNLYDYDSDSFDLIETI 599

Query: 235 KNSYYLVSLVDNNYIN 188
           +++YYL +++DN+YI+
Sbjct: 600 RDTYYLCAIIDNDYIS 615

[60][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
           neoformans RepID=Q5KN82_CRYNE
          Length = 633

 Score =  139 bits (350), Expect = 2e-31
 Identities = 65/136 (47%), Positives = 96/136 (70%), Gaps = 2/136 (1%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS--ITYMAVNKSENWVSN 422
           KS+   +GWG  GGYV+QKA++EFF ++D+++ L EK +      IT  A N+  ++ +N
Sbjct: 484 KSEDEVVGWGPRGGYVFQKAFVEFFVTEDEVNRLKEKVEREGKGLITMYAANRKGDFKTN 543

Query: 421 TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
           T +  VNAVTWGVFP +E+ Q TI++  SF  WK+EAF+IW+  W+ LYP + PSRKLLE
Sbjct: 544 TDKDSVNAVTWGVFPGQEIAQSTIIEETSFLAWKEEAFDIWA-EWSLLYPRNTPSRKLLE 602

Query: 241 EVKNSYYLVSLVDNNY 194
            + N ++LVSL+ ++Y
Sbjct: 603 GIANEWWLVSLIHHDY 618

[61][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
           S238N-H82 RepID=B0CU22_LACBS
          Length = 602

 Score =  139 bits (350), Expect = 2e-31
 Identities = 69/144 (47%), Positives = 94/144 (65%), Gaps = 1/144 (0%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           +SD P  GWG   GYVYQKAYLEFF +   L+ L+   +   +ITY  +NK  +  +NT 
Sbjct: 440 RSDDPVFGWGPSNGYVYQKAYLEFFVNPTLLNLLLTHIERDSNITYYVINKRGDLRTNTH 499

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
               NAVTWGVFP KE++QPTIV+  SF  WKDEAFE+  + WA LY  + PS+KL+ E+
Sbjct: 500 SDGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFEL-GQQWAKLYEANSPSQKLITEL 558

Query: 235 KNSYYLVSLVDNNYINGD-IFSVF 167
            ++ +LV++V N++   D IF  F
Sbjct: 559 MDTCFLVNVVHNDFHEPDAIFKPF 582

[62][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
           (NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
          Length = 644

 Score =  139 bits (349), Expect = 2e-31
 Identities = 66/135 (48%), Positives = 88/135 (65%), Gaps = 2/135 (1%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTL-VEKSKAFPSITYMAVNKSENWV-SNT 419
           S  P  GWG  GGY+ QKAYLEFF +K   + L     K  P + Y  +NK      +N 
Sbjct: 466 STHPIYGWGDKGGYISQKAYLEFFINKHYAEALKTVLPKYHPRVNYHMINKCGTTDHTNA 525

Query: 418 GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEE 239
             S+ NAVTWG+F  KE+IQPT+VDP SF VWKDEAF +W   WA+LY +   SR+++ +
Sbjct: 526 DRSNPNAVTWGIFAGKEIIQPTVVDPVSFIVWKDEAFGLWHERWASLYEKGSKSREIIND 585

Query: 238 VKNSYYLVSLVDNNY 194
           + ++YYLV+LVDN+Y
Sbjct: 586 IADNYYLVNLVDNDY 600

[63][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
           RepID=Q2H0T7_CHAGB
          Length = 616

 Score =  137 bits (345), Expect = 6e-31
 Identities = 68/143 (47%), Positives = 91/143 (63%), Gaps = 1/143 (0%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS  P  GWG   GYVYQKAYLE   S +    +  + ++ P +TY AV KS N  +N  
Sbjct: 439 KSTHPIHGWGPANGYVYQKAYLEMLISPELFPQIKSRIESHPDLTYHAVTKSGNLHTNAQ 498

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
               NAVTWGVFP KE++QPTIV+  SF  WKDEAF++    WA  Y    PSR +L+E+
Sbjct: 499 FEGPNAVTWGVFPGKEIVQPTIVERISFLAWKDEAFQL-GMEWARCYETGTPSRSILDEI 557

Query: 235 KNSYYLVSLVDNNYINGD-IFSV 170
            N++YLV++V+N++  G+ IF V
Sbjct: 558 MNTWYLVNIVNNDFHRGETIFEV 580

[64][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
           okayama7#130 RepID=A8N945_COPC7
          Length = 574

 Score =  137 bits (344), Expect = 8e-31
 Identities = 70/144 (48%), Positives = 92/144 (63%), Gaps = 1/144 (0%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           +SD    GWG   GYVYQKAYLEFF     L  L++  +   +ITY  +NK  +  +NT 
Sbjct: 400 RSDDKIFGWGPSNGYVYQKAYLEFFVDPALLQLLLKHLERDTNITYHVINKRGDLQTNTH 459

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
               NAVTWGVFP KE+IQPTIV+  SF  WKDEA+E+ ++ WA LY  D PS+KL+  +
Sbjct: 460 SEGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAYELGAQ-WARLYEHDSPSQKLILNL 518

Query: 235 KNSYYLVSLVDNNYINGD-IFSVF 167
             +Y LV++V N++ N D IF  F
Sbjct: 519 MENYALVNVVHNDFHNPDAIFEPF 542

[65][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
           RepID=Q7S830_NEUCR
          Length = 613

 Score =  136 bits (343), Expect = 1e-30
 Identities = 65/134 (48%), Positives = 85/134 (63%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS  P  GWG   GYVYQKAYLE   S +    +  + +  P ITY AV KS N  +N  
Sbjct: 439 KSTHPVHGWGPANGYVYQKAYLELLVSPELFPEIKRRIEDHPDITYYAVTKSGNLHTNAP 498

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
               NAVTWGVFP KE++QPTIV+  SF  WKDEAF++    WA  Y  D PSR L+EE+
Sbjct: 499 SEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQL-GLEWARCYDADTPSRLLIEEI 557

Query: 235 KNSYYLVSLVDNNY 194
            + +YL+++V+N++
Sbjct: 558 MDKWYLINIVNNDF 571

[66][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
           RepID=B2B2M5_PODAN
          Length = 610

 Score =  135 bits (341), Expect = 2e-30
 Identities = 67/138 (48%), Positives = 88/138 (63%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS  P  GWG   GYVYQKAYLE   S +    + ++ +  P +TY AV KS    +N  
Sbjct: 439 KSTHPVHGWGPSKGYVYQKAYLELLVSPEVYPEIKKRIENHPDLTYHAVTKSGMLETNAP 498

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
               NAVTWGVFP KE++QPTIV+  SF  WKDEAF++ S  WA  Y  D PSR LLE++
Sbjct: 499 SDAPNAVTWGVFPGKEIVQPTIVERISFLAWKDEAFQLGS-DWARCYEADTPSRLLLEDI 557

Query: 235 KNSYYLVSLVDNNYINGD 182
             S+YLV++V+N++  G+
Sbjct: 558 MKSWYLVNIVNNDFHQGE 575

[67][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
           ATCC 10500 RepID=B8M3Q9_TALSN
          Length = 607

 Score =  135 bits (340), Expect = 2e-30
 Identities = 65/144 (45%), Positives = 94/144 (65%), Gaps = 1/144 (0%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS  P  GWG   GYVYQKAYLE     + +D L+ + +  P +TY  VNK+    + + 
Sbjct: 440 KSTDPVHGWGPRNGYVYQKAYLELLVPPEHVDELLRRIEKNPDLTYYCVNKTGELKARSD 499

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           E   NAVTWG+F +KE+IQPTIV+  SF  WKDEA+++    WA  +P D PSRKL++ V
Sbjct: 500 EGP-NAVTWGIFASKEIIQPTIVESVSFMAWKDEAYQL-GEDWAKCHPADSPSRKLIQRV 557

Query: 235 KNSYYLVSLVDNNY-INGDIFSVF 167
            + +Y++++V+N++  N DIF +F
Sbjct: 558 MDEWYILNIVNNDFHKNDDIFRLF 581

[68][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
           pombe RepID=MTHR1_SCHPO
          Length = 603

 Score =  133 bits (335), Expect = 9e-30
 Identities = 67/144 (46%), Positives = 88/144 (61%), Gaps = 1/144 (0%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS  P  GWG P GYV+QK Y+EFF     L+ L E  K   S++Y   NK+ +  +N+ 
Sbjct: 442 KSSHPVFGWGPPNGYVFQKPYVEFFVHPSLLNELKETVKKLNSVSYFVTNKNGDLDTNSQ 501

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
               NAVTWGVFP +E+IQPTIV+  SF  WKDEA+ +    WAN Y  D  SRKLL  +
Sbjct: 502 YEIPNAVTWGVFPNREIIQPTIVESTSFLAWKDEAYSL-GMEWANAYSPDSISRKLLVSM 560

Query: 235 KNSYYLVSLVDNNYING-DIFSVF 167
              ++L  +VDN++ NG  +F VF
Sbjct: 561 MKEWFLCVIVDNDFQNGQSLFDVF 584

[69][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
           RepID=A8PV87_BRUMA
          Length = 656

 Score =  132 bits (333), Expect = 2e-29
 Identities = 67/135 (49%), Positives = 87/135 (64%), Gaps = 2/135 (1%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSE--NWVSNT 419
           S  P +GWG PGGY YQKAYLEFF S+   + L     ++  +    VN     +W +NT
Sbjct: 508 STDPFVGWGKPGGYCYQKAYLEFFTSQANAEVLWSLLPSYSRLNCHIVNHDATIDW-TNT 566

Query: 418 GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEE 239
             +   AVTWGVFP  E+ QPT+VDP SF+VWKDEAF  W  +W+++Y E   SR LLE+
Sbjct: 567 ETTMPIAVTWGVFPGSEIAQPTVVDPLSFRVWKDEAFSAW-LNWSSIYAEGTSSRCLLEK 625

Query: 238 VKNSYYLVSLVDNNY 194
           + N Y LV+LVDN+Y
Sbjct: 626 IYNEYCLVTLVDNDY 640

[70][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
           RepID=Q6CG63_YARLI
          Length = 583

 Score =  132 bits (331), Expect = 3e-29
 Identities = 68/145 (46%), Positives = 94/145 (64%), Gaps = 1/145 (0%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS  P  GWG   GYVYQKAYLE   + +  + LV+K +    IT+ AVNK+ N  +N  
Sbjct: 439 KSTHPVHGWGPKNGYVYQKAYLELLVTPEVAEKLVKKLENQSEITFYAVNKTGNLQTNA- 497

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
               NAVTWG++P KEVIQPTIV+  SF  WK+EAF + S  WA  YP +  SRK L+++
Sbjct: 498 PGGPNAVTWGIYPGKEVIQPTIVEKISFLAWKEEAFRLGS-EWAKCYPAESESRKFLDDI 556

Query: 235 KNSYYLVSLVDNNYING-DIFSVFA 164
            N++YLV++V N++ +   IF +F+
Sbjct: 557 FNNWYLVNIVHNDFHDSTGIFDLFS 581

[71][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
           RepID=Q4X140_ASPFU
          Length = 615

 Score =  131 bits (330), Expect = 4e-29
 Identities = 63/144 (43%), Positives = 94/144 (65%), Gaps = 1/144 (0%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           +S  P  GWG   G+VYQKAYLE F     LD L+ + +  P +TY AV K+    +NT 
Sbjct: 439 RSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLTYHAVAKNRELRTNTR 498

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           +S  NA+TWG+F  +E++QPTIVD  SF  WKDEA+ +    WA  +    PSRKL++++
Sbjct: 499 DSP-NALTWGIFAGREIVQPTIVDTISFLAWKDEAYRL-GEDWAKCHDASSPSRKLIQDI 556

Query: 235 KNSYYLVSLVDNNYING-DIFSVF 167
            +++YLV++V+N++ N  D+F +F
Sbjct: 557 MDNWYLVNIVNNDFHNTYDLFDLF 580

[72][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
           ATCC 18224 RepID=B6QPH8_PENMQ
          Length = 607

 Score =  131 bits (330), Expect = 4e-29
 Identities = 63/144 (43%), Positives = 94/144 (65%), Gaps = 1/144 (0%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS  P  GWG   G+VYQKAYLE     + ++ L+ + +  P +TY  +NK+    + + 
Sbjct: 440 KSTDPVHGWGPRNGFVYQKAYLELLVPPEHVEELLRRIEKNPDLTYYCINKTGELRARSD 499

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           E   NAVTWG+F +KE+IQPTIV+  SF  WKDEA+++    WA  +P D PSRKLL+ V
Sbjct: 500 EGP-NAVTWGIFASKEIIQPTIVESVSFMAWKDEAYQL-GDDWAKCHPADSPSRKLLQRV 557

Query: 235 KNSYYLVSLVDNNY-INGDIFSVF 167
            + +Y++++V+N++  N DIF +F
Sbjct: 558 MDEWYILNIVNNDFHKNDDIFRLF 581

[73][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
           A1163 RepID=B0XSG0_ASPFC
          Length = 615

 Score =  131 bits (330), Expect = 4e-29
 Identities = 63/144 (43%), Positives = 94/144 (65%), Gaps = 1/144 (0%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           +S  P  GWG   G+VYQKAYLE F     LD L+ + +  P +TY AV K+    +NT 
Sbjct: 439 RSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLTYHAVAKNRELRTNTR 498

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           +S  NA+TWG+F  +E++QPTIVD  SF  WKDEA+ +    WA  +    PSRKL++++
Sbjct: 499 DSP-NALTWGIFAGREIVQPTIVDTISFLAWKDEAYRL-GEDWAKCHDASSPSRKLIQDI 556

Query: 235 KNSYYLVSLVDNNYING-DIFSVF 167
            +++YLV++V+N++ N  D+F +F
Sbjct: 557 MDNWYLVNIVNNDFHNTYDLFDLF 580

[74][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
           RepID=UPI000023D9F4
          Length = 621

 Score =  131 bits (329), Expect = 5e-29
 Identities = 64/134 (47%), Positives = 81/134 (60%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS  P  GWG   GYVYQK+YLE        D ++ + +  P +TY AV K     SN  
Sbjct: 439 KSSHPIHGWGPDNGYVYQKSYLELLVHPGVFDKMISRIENHPDLTYYAVTKDGELRSNVT 498

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
               NAVTWGVFP KE++QPTIV+  SF  WKDEAF +    WA+ Y    PSR LLE V
Sbjct: 499 SDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRL-GVDWAHCYDISSPSRALLEGV 557

Query: 235 KNSYYLVSLVDNNY 194
            N +YLV++V+N++
Sbjct: 558 MNDWYLVNIVNNDF 571

[75][TOP]
>UniRef100_Q8MQE7 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis elegans
           RepID=Q8MQE7_CAEEL
          Length = 642

 Score =  131 bits (329), Expect = 5e-29
 Identities = 60/136 (44%), Positives = 90/136 (66%), Gaps = 3/136 (2%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEK-SKAFP-SITYMAVNKSENW-VSN 422
           S  P +GWG PGGY YQKAYLE F + +  D L++   + FP  + Y A+NK   +  +N
Sbjct: 488 STDPLVGWGKPGGYCYQKAYLECFMTAELSDKLIQIIEREFPVRVNYHAINKDSTFDKTN 547

Query: 421 TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
           + E+   AVTWGVFP  E+ QPT+VDP SF+ W+DEA+++W   W + YP++  S  +++
Sbjct: 548 SEETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQWGDFYPKESKSYGVIK 607

Query: 241 EVKNSYYLVSLVDNNY 194
            V + + LV+LVDN++
Sbjct: 608 AVHDEFRLVTLVDNDF 623

[76][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
           G186AR RepID=C0NNE8_AJECG
          Length = 633

 Score =  131 bits (329), Expect = 5e-29
 Identities = 64/143 (44%), Positives = 93/143 (65%), Gaps = 1/143 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 413
           S  P  GWG   GYVYQKAYLE   S   +D ++ + +  P +TY  VNK     +NT +
Sbjct: 440 SSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKKGELRTNTTD 499

Query: 412 SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
           S  NAVTWG+F +KE+IQPTIV+  SF  WKDEA+ +    WA  +    PSR+++++V 
Sbjct: 500 SP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHVASSPSRRIIQQVM 557

Query: 232 NSYYLVSLVDNNY-INGDIFSVF 167
           +S+YLV++V+N++    DIF++F
Sbjct: 558 DSWYLVNIVNNDFHKTHDIFNIF 580

[77][TOP]
>UniRef100_Q17693 Probable methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis
           elegans RepID=MTHR_CAEEL
          Length = 663

 Score =  131 bits (329), Expect = 5e-29
 Identities = 60/136 (44%), Positives = 90/136 (66%), Gaps = 3/136 (2%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEK-SKAFP-SITYMAVNKSENW-VSN 422
           S  P +GWG PGGY YQKAYLE F + +  D L++   + FP  + Y A+NK   +  +N
Sbjct: 509 STDPLVGWGKPGGYCYQKAYLECFMTAELSDKLIQIIEREFPVRVNYHAINKDSTFDKTN 568

Query: 421 TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
           + E+   AVTWGVFP  E+ QPT+VDP SF+ W+DEA+++W   W + YP++  S  +++
Sbjct: 569 SEETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQWGDFYPKESKSYGVIK 628

Query: 241 EVKNSYYLVSLVDNNY 194
            V + + LV+LVDN++
Sbjct: 629 AVHDEFRLVTLVDNDF 644

[78][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
           H143 RepID=C6H337_AJECH
          Length = 524

 Score =  130 bits (327), Expect = 8e-29
 Identities = 64/143 (44%), Positives = 93/143 (65%), Gaps = 1/143 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 413
           S  P  GWG   GYVYQKAYLE   S   +D ++ + +  P +TY  VNK     +NT +
Sbjct: 331 SSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKIGELRTNTTD 390

Query: 412 SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
           S  NAVTWG+F +KE+IQPTIV+  SF  WKDEA+ +    WA  +    PSR+++++V 
Sbjct: 391 SP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHVASSPSRRIIQQVM 448

Query: 232 NSYYLVSLVDNNY-INGDIFSVF 167
           +S+YLV++V+N++    DIF++F
Sbjct: 449 DSWYLVNIVNNDFHKTHDIFNIF 471

[79][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
           RepID=Q0U6C4_PHANO
          Length = 657

 Score =  130 bits (326), Expect = 1e-28
 Identities = 65/160 (40%), Positives = 96/160 (60%), Gaps = 1/160 (0%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS  P  GWG   GYVYQKAYLE   S + +  ++ + +  P  TY AVNK  +  +N  
Sbjct: 439 KSSDPTFGWGPRNGYVYQKAYLEVLVSPEYIAEIITRIERDPEFTYYAVNKDGDLKTNAP 498

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
               NAVTWGVFP KE++QPTIV+  SF  WKDE + +  + WAN +    PSR ++++V
Sbjct: 499 NEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRL-GQQWANCHGGASPSRFVIQDV 557

Query: 235 KNSYYLVSLVDNNY-INGDIFSVFA*SPRKPPAKRKHSIS 119
            +++YL+++V N++     IF +F     K   K+ HS++
Sbjct: 558 VDTWYLLNIVHNDFHATRGIFPIFDGLQVKDIDKKLHSVN 597

[80][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
           NRRL 181 RepID=A1DH45_NEOFI
          Length = 615

 Score =  130 bits (326), Expect = 1e-28
 Identities = 62/144 (43%), Positives = 94/144 (65%), Gaps = 1/144 (0%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           +S  P  GWG   G+VYQKAYLE F     LD L+ + +  P +TY AV K+    +NT 
Sbjct: 439 RSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLTYHAVAKNRELRTNTR 498

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           +S  NA+TWG+F  +E++QPTIV+  SF  WKDEA+ +    WA  +    PSRKL++++
Sbjct: 499 DSP-NALTWGIFAGREIVQPTIVETISFLAWKDEAYRL-GEDWAKCHDASSPSRKLIQDI 556

Query: 235 KNSYYLVSLVDNNYING-DIFSVF 167
            +++YLV++V+N++ N  D+F +F
Sbjct: 557 MDNWYLVNIVNNDFHNTYDLFDLF 580

[81][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
           RepID=Q4T956_TETNG
          Length = 845

 Score =  129 bits (324), Expect = 2e-28
 Identities = 56/120 (46%), Positives = 78/120 (65%), Gaps = 1/120 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYVYQKAYLEFF S + +  L++  K + P + Y  VN     ++N  
Sbjct: 497 STDPIVGWGPAGGYVYQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGRNLTNAP 556

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           +   NAVTWG+F  +E++QPT+VDP SF  WKDEAF +W   WA LY ++ PSR +++ +
Sbjct: 557 DMQPNAVTWGIFAGREIVQPTVVDPVSFMSWKDEAFALWIEQWAKLYEDESPSRMIIQYI 616

[82][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
           RepID=Q1DNB1_COCIM
          Length = 629

 Score =  129 bits (324), Expect = 2e-28
 Identities = 64/143 (44%), Positives = 92/143 (64%), Gaps = 1/143 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 413
           S  P  GWG   GYVYQKAYLE     + +  ++ + +  P +TY A+NK+    +NT +
Sbjct: 440 SSHPVYGWGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNPDLTYYAINKNGELKTNTSD 499

Query: 412 SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
           S  NAVTWG+F +KEVIQPTIV+  SF  WKDEAF +    WA  +    PSR+L++ V 
Sbjct: 500 SP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAFRL-GDDWAKCHDARSPSRQLIQRVM 557

Query: 232 NSYYLVSLVDNNY-INGDIFSVF 167
           + +YLV++V+N++    DIF++F
Sbjct: 558 DEWYLVNIVNNDFHKTHDIFNLF 580

[83][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
           brasiliensis Pb01 RepID=C1GYS1_PARBA
          Length = 629

 Score =  129 bits (324), Expect = 2e-28
 Identities = 63/143 (44%), Positives = 93/143 (65%), Gaps = 1/143 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 413
           S  P  GWG   GYVYQKAYLE   S   ++ ++ + +    +TY  VNK+    +NT +
Sbjct: 440 SSHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVNKTGELRTNTSD 499

Query: 412 SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
           S  NAVTWG+F +KE+IQPTIV+  SF  WKDEA+ +    WA  +P   PSR+L+++V 
Sbjct: 500 SP-NAVTWGIFVSKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHPASSPSRRLIQQVM 557

Query: 232 NSYYLVSLVDNNY-INGDIFSVF 167
           +++YLV++V+N++    DIF +F
Sbjct: 558 DTWYLVNIVNNDFHRTHDIFDLF 580

[84][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
           brasiliensis Pb03 RepID=C0RZ73_PARBP
          Length = 629

 Score =  129 bits (324), Expect = 2e-28
 Identities = 63/143 (44%), Positives = 93/143 (65%), Gaps = 1/143 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 413
           S  P  GWG   GYVYQKAYLE   S   ++ ++ + +    +TY  VNK+    +NT +
Sbjct: 440 SSHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVNKTGELRTNTSD 499

Query: 412 SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
           S  NAVTWG+F +KE+IQPTIV+  SF  WKDEA+ +    WA  +P   PSR+L+++V 
Sbjct: 500 SP-NAVTWGIFVSKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHPASSPSRRLIQQVM 557

Query: 232 NSYYLVSLVDNNY-INGDIFSVF 167
           +++YLV++V+N++    DIF +F
Sbjct: 558 DTWYLVNIVNNDFHRTHDIFDLF 580

[85][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
           tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
          Length = 646

 Score =  129 bits (324), Expect = 2e-28
 Identities = 58/134 (43%), Positives = 86/134 (64%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS  P  GWG   GYVYQKAYLE F S + +  ++ + +  P  TY AVNK  +  +N  
Sbjct: 439 KSSDPVFGWGPRNGYVYQKAYLEVFVSPEYISEIITRLERDPEFTYYAVNKDGDLKTNAP 498

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
               NAVTWGVFP KE++QPTIV+  SF  WKDE + +  + WAN +    PSR +++++
Sbjct: 499 NEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRL-GQQWANCHAGVSPSRYVIQDI 557

Query: 235 KNSYYLVSLVDNNY 194
            +++YL+++V N++
Sbjct: 558 VDTWYLLNIVHNDF 571

[86][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
           NAm1 RepID=A6RBU9_AJECN
          Length = 619

 Score =  129 bits (324), Expect = 2e-28
 Identities = 63/143 (44%), Positives = 93/143 (65%), Gaps = 1/143 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 413
           S  P  GWG   GYVYQKAYLE   S   +D ++ + +  P +TY  VNK     +NT +
Sbjct: 426 SSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKIGELRTNTTD 485

Query: 412 SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
           S  NAVTWG+F +KE+IQPTIV+  SF  WKDEA+ +    WA  +    PSR+++++V 
Sbjct: 486 SP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHGASSPSRRIIQQVM 543

Query: 232 NSYYLVSLVDNNY-INGDIFSVF 167
           +++YLV++V+N++    DIF++F
Sbjct: 544 DNWYLVNIVNNDFHKTHDIFNIF 566

[87][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
           C735 delta SOWgp RepID=C5PJM0_COCP7
          Length = 629

 Score =  129 bits (323), Expect = 2e-28
 Identities = 64/143 (44%), Positives = 91/143 (63%), Gaps = 1/143 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 413
           S  P  GWG   GYVYQKAYLE     + +  ++ + +  P +TY A+NK+    +NT +
Sbjct: 440 SSHPVYGWGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNPDLTYYAINKNGELKTNTSD 499

Query: 412 SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
           S  NAVTWG+F +KEVIQPTIV+  SF  WKDEAF +    WA  +    PSR+L++ V 
Sbjct: 500 SP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAFRL-GDDWAKCHDARSPSRQLIQRVM 557

Query: 232 NSYYLVSLVDNNY-INGDIFSVF 167
           + +YLV++V+N++    DIF +F
Sbjct: 558 DEWYLVNIVNNDFHKTHDIFDLF 580

[88][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
           RepID=C7Z4M2_NECH7
          Length = 618

 Score =  128 bits (322), Expect = 3e-28
 Identities = 64/143 (44%), Positives = 87/143 (60%), Gaps = 1/143 (0%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS     GWG   GYVYQK+YLE     D  + ++ + +  P +T+ AV K     SN  
Sbjct: 439 KSSHAVHGWGPSNGYVYQKSYLELLVHPDVFNDMIGRIENHPDLTFYAVTKDGELRSNAP 498

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
               NAVTWGVFP KE++QPTIV+  SF  WKDEAF +    WA+ Y  + PSR L++EV
Sbjct: 499 SDCPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRL-GVDWAHCYDANSPSRALIDEV 557

Query: 235 KNSYYLVSLVDNNY-INGDIFSV 170
            N +YLV++V+N++  N  IF +
Sbjct: 558 MNEWYLVNIVNNDFHQNATIFEL 580

[89][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
           brasiliensis Pb18 RepID=C1G7L7_PARBD
          Length = 629

 Score =  128 bits (322), Expect = 3e-28
 Identities = 63/143 (44%), Positives = 93/143 (65%), Gaps = 1/143 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 413
           S  P  GWG   GYVYQKAYLE   S   ++ ++ + +    +TY  VNK+    +NT +
Sbjct: 440 SSHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVNKTGELRTNTTD 499

Query: 412 SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
           S  NAVTWG+F +KE+IQPTIV+  SF  WKDEA+ +    WA  +P   PSR+L+++V 
Sbjct: 500 SP-NAVTWGIFVSKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHPASSPSRRLIQQVM 557

Query: 232 NSYYLVSLVDNNY-INGDIFSVF 167
           +++YLV++V+N++    DIF +F
Sbjct: 558 DTWYLVNIVNNDFHRTHDIFDLF 580

[90][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
           RepID=A4RJT6_MAGGR
          Length = 626

 Score =  128 bits (322), Expect = 3e-28
 Identities = 61/134 (45%), Positives = 84/134 (62%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           +S  P  GWG P GYVYQKAYLE        + L E+    P +TY AV KS N  +N  
Sbjct: 434 RSTHPIHGWGPPNGYVYQKAYLELLVHPAIFEQLKERIHDHPDLTYYAVTKSGNLHTNAT 493

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
               NAVTWGVFP KE++QPT+V+  SF  WKDEAF++    WA  + ++ PSR L++ +
Sbjct: 494 YEGPNAVTWGVFPGKEIVQPTVVENISFLAWKDEAFQL-GMEWARCHDQNTPSRILIQSM 552

Query: 235 KNSYYLVSLVDNNY 194
              +YLV++V+N++
Sbjct: 553 MQEWYLVNIVNNDF 566

[91][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
           sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
          Length = 590

 Score =  128 bits (321), Expect = 4e-28
 Identities = 62/134 (46%), Positives = 83/134 (61%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS  P  GWG   GYVYQKAYLE   + D +  LV + +  P +TY AV K+ +  +N  
Sbjct: 439 KSSDPVYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQHDPDLTYYAVKKTGDLQTNAQ 498

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
               NAVTWGVFP KE++QPTIV+  SF  WKDEAF +    WA+ +    PSR L+E +
Sbjct: 499 SDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRL-GTDWAHCHSALSPSRGLIESI 557

Query: 235 KNSYYLVSLVDNNY 194
            +S+YLV++   N+
Sbjct: 558 MDSWYLVNIGRANF 571

[92][TOP]
>UniRef100_UPI0000123E6B Hypothetical protein CBG12960 n=1 Tax=Caenorhabditis briggsae AF16
           RepID=UPI0000123E6B
          Length = 662

 Score =  127 bits (319), Expect = 7e-28
 Identities = 56/136 (41%), Positives = 92/136 (67%), Gaps = 3/136 (2%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEK-SKAFP-SITYMAVNKSENW-VSN 422
           S  P +GWG PGGY YQKAYLE F + +  + L++   + +P  + Y A++K  ++  +N
Sbjct: 510 STDPLVGWGKPGGYCYQKAYLECFMTAELSEKLIDIIEREYPVRVNYHAIDKDSSFDKTN 569

Query: 421 TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
           + E+   AVTWGVFP  E+ QPT+VDP SF+ W+DEA+++W   W + YP++  S  +++
Sbjct: 570 SEETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQWGDFYPKESKSYGVIK 629

Query: 241 EVKNSYYLVSLVDNNY 194
            + +++ LV+LVDN++
Sbjct: 630 SIHDTFRLVTLVDNDF 645

[93][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
           [Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
           nidulans RepID=C8UZX0_EMENI
          Length = 627

 Score =  127 bits (319), Expect = 7e-28
 Identities = 63/144 (43%), Positives = 92/144 (63%), Gaps = 1/144 (0%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS  P  GWG   G+VYQKAYLE       +D L+ + +A   +TY AV K     +NT 
Sbjct: 439 KSSHPVFGWGPKNGFVYQKAYLELLVPPYVIDELIARIEANEDLTYHAVTKKGELRTNTR 498

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           +S  NA+TWG+F  +EV+QPTIV+  SF  WKDEA+++    WA  +    P+RKLL+ +
Sbjct: 499 DSP-NALTWGIFAGREVVQPTIVETVSFLAWKDEAYQL-GEDWAKCHEASSPTRKLLQGI 556

Query: 235 KNSYYLVSLVDNNYING-DIFSVF 167
            +S+YLV++V+N++ N  D+F +F
Sbjct: 557 MDSWYLVNIVNNDFHNTYDLFELF 580

[94][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
           RepID=C4R2Q6_PICPG
          Length = 603

 Score =  127 bits (319), Expect = 7e-28
 Identities = 65/157 (41%), Positives = 96/157 (61%), Gaps = 21/157 (13%)
 Frame = -2

Query: 574 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEK--------SKAFPSITYMAVNKSENWVSNT 419
           GWG   G+VYQK YLEFF     L  L+          S  F ++T+ AVN     ++N+
Sbjct: 444 GWGPSNGFVYQKQYLEFFIPAKFLTKLISNIEELNKSYSSNFNTLTFYAVNAQGELITNS 503

Query: 418 GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPE---------- 269
            E D+NAVTWG+FP KEV+QPTIV+  SF  WKDEAF ++ ++W++L+ +          
Sbjct: 504 KEDDINAVTWGIFPGKEVVQPTIVERCSFLAWKDEAFRVF-KAWSSLFKDQDQDEFEVLR 562

Query: 268 DDPSRKLLEEVKNSYYLVSLVDNNYI---NGDIFSVF 167
           D  +R +L+++ + Y+LV++VDNNY+   N  IF +F
Sbjct: 563 DSKTRAVLDKLHDEYFLVNIVDNNYVQNPNVKIFDLF 599

[95][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
           Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
          Length = 574

 Score =  127 bits (318), Expect = 9e-28
 Identities = 58/128 (45%), Positives = 81/128 (63%), Gaps = 1/128 (0%)
 Frame = -2

Query: 574 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVS-NTGESDVNA 398
           GWGG GG VYQKAY E F S  K + L +     PS+   AVN +   +     E  V A
Sbjct: 447 GWGGKGGRVYQKAYFECFVSPSKANRLTQMVTDHPSLNMYAVNNAGQELRVGVEEGGVTA 506

Query: 397 VTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYL 218
           +TWGVFP +E++QPTI DP +F +W +EAF +W   W NLY     S  L++E++++YYL
Sbjct: 507 LTWGVFPNREILQPTIFDPDTFLIWAEEAFSLWGSMWLNLYEYGSESYDLVQEIRDTYYL 566

Query: 217 VSLVDNNY 194
           V+L+DN++
Sbjct: 567 VALIDNDF 574

[96][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
           RepID=A1C6H3_ASPCL
          Length = 619

 Score =  127 bits (318), Expect = 9e-28
 Identities = 64/144 (44%), Positives = 92/144 (63%), Gaps = 1/144 (0%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           +S  P  GWG   G+VYQKAYLE F     LD L+ + +    +TY AV K     +NT 
Sbjct: 439 RSSHPVYGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNDDLTYHAVAKEGELRTNTR 498

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           +S  NA+TWG+F  +E++QPTIV+  SF  WKDEA+ +    WA  +    PSRKL++EV
Sbjct: 499 DSP-NALTWGIFAGREIVQPTIVETISFLAWKDEAYRL-GEDWAKCHEAASPSRKLIQEV 556

Query: 235 KNSYYLVSLVDNNYING-DIFSVF 167
            +S+YLV++V+N++ N  D+F +F
Sbjct: 557 VDSWYLVNIVNNDFHNTYDLFELF 580

[97][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
           113480 RepID=C5FFF6_NANOT
          Length = 623

 Score =  126 bits (317), Expect = 1e-27
 Identities = 61/144 (42%), Positives = 91/144 (63%), Gaps = 1/144 (0%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS  P  GWG   GYVYQKAYLE   S   +D ++ + +  P +TY  +NK+    +N+ 
Sbjct: 439 KSSHPIYGWGPKNGYVYQKAYLELLISPTLIDEVIRRIETNPDLTYHCINKNGELRTNSS 498

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           ++  NAVTWG+F +KEVIQPTIV+  SF  WKDEA+ +    WA  +    PSRK+++  
Sbjct: 499 DTP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRL-GDDWAKCHDASSPSRKIIQNT 556

Query: 235 KNSYYLVSLVDNNY-INGDIFSVF 167
            +++YL ++V+N++    DIF +F
Sbjct: 557 MDTWYLFNIVNNDFHKTHDIFDLF 580

[98][TOP]
>UniRef100_B6JY06 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
           japonicus yFS275 RepID=B6JY06_SCHJY
          Length = 626

 Score =  126 bits (316), Expect = 1e-27
 Identities = 57/135 (42%), Positives = 84/135 (62%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 413
           S     GWG  GG+V+QKA++E F S    + L ++    P ITY+A N    + +N   
Sbjct: 483 SSHAIFGWGPRGGWVFQKAFVEMFMSTMDFEALAQRLHDNPQITYLAGNNKGEFKTNASL 542

Query: 412 SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
              NAVTWGVFP +E+IQ TI+ P SF+ W+DEA+ IW   WA LYP   PS KL++   
Sbjct: 543 DSANAVTWGVFPGREIIQSTIIAPVSFQAWRDEAYSIWG-EWARLYPAGTPSHKLIQSCI 601

Query: 232 NSYYLVSLVDNNYIN 188
           ++ +LVS++ +N+++
Sbjct: 602 DNCWLVSVIHHNFLD 616

[99][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
           RepID=Q4P1E8_USTMA
          Length = 684

 Score =  125 bits (315), Expect = 2e-27
 Identities = 57/136 (41%), Positives = 93/136 (68%), Gaps = 3/136 (2%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCS---KDKLDTLVEKSKAFPSITYMAVNKSENWVSN 422
           S  P +G+G PGG+V+QK+++E F S   KD+L   ++   A   ITY A N   ++ SN
Sbjct: 538 STDPIVGFGPPGGFVFQKSFVELFVSSSDKDRLVARIDALGASAPITYFAGNAKGDFQSN 597

Query: 421 TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
            G+ + N VTW VFP KE++Q TI++  SF+ W++EAFEIW+  W+ L+P+   SR+L++
Sbjct: 598 LGDEEANTVTWAVFPGKEIVQSTIIERQSFEAWREEAFEIWA-EWSLLFPKKSASRQLID 656

Query: 241 EVKNSYYLVSLVDNNY 194
           E++ + +LV++V ++Y
Sbjct: 657 EIREARWLVTVVHHDY 672

[100][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
           1704 RepID=C4JG55_UNCRE
          Length = 625

 Score =  125 bits (314), Expect = 3e-27
 Identities = 63/143 (44%), Positives = 90/143 (62%), Gaps = 1/143 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 413
           S  P  GWG   GYVYQKAYLE     + +D ++ + +    +TY A NK+    +NT +
Sbjct: 440 SSHPVYGWGPKNGYVYQKAYLELLIPPEIIDEVITRIQKNADLTYYATNKNGELKTNTSD 499

Query: 412 SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
           S  NAVTWG+F +KEVIQPTIV+  SF  WKDEA+ +    WA  +    PSR+L++ V 
Sbjct: 500 SP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRL-GDDWAKCHDARSPSRQLIQRVM 557

Query: 232 NSYYLVSLVDNNY-INGDIFSVF 167
           + +YLV++V+N++    DIF +F
Sbjct: 558 DEWYLVNIVNNDFHKTHDIFDLF 580

[101][TOP]
>UniRef100_A8XGR9 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis briggsae
           RepID=A8XGR9_CAEBR
          Length = 724

 Score =  125 bits (313), Expect = 3e-27
 Identities = 56/146 (38%), Positives = 93/146 (63%), Gaps = 13/146 (8%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEK-SKAFP-SITYMAVNKSENWV--- 428
           S  P +GWG PGGY YQKAYLE F + +  + L++   + +P  + Y A++K  +++   
Sbjct: 560 STDPLVGWGKPGGYCYQKAYLECFMTAELSEKLIDIIEREYPVRVNYHAIDKDVSYILNS 619

Query: 427 --------SNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYP 272
                   +N+ E+   AVTWGVFP  E+ QPT+VDP SF+ W+DEA+++W   W + YP
Sbjct: 620 HDSMQIFRTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQWGDFYP 679

Query: 271 EDDPSRKLLEEVKNSYYLVSLVDNNY 194
           ++  S  +++ + +++ LV+LVDN++
Sbjct: 680 KESKSYGVIKSIHDTFRLVTLVDNDF 705

[102][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
           dermatitidis SLH14081 RepID=C5JE18_AJEDS
          Length = 633

 Score =  125 bits (313), Expect = 3e-27
 Identities = 63/143 (44%), Positives = 91/143 (63%), Gaps = 1/143 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 413
           S  P  GWG   GYVYQKAYLE   S   +D ++ + +    +TY  VNK     +NT +
Sbjct: 440 SSHPIYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNSDLTYYCVNKKGELKTNTTD 499

Query: 412 SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
           S  NAVTWG+F +KE+IQPTIV+  SF  WKDEA+ +    WA  +     SR+L+E+V 
Sbjct: 500 SP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHAPSSLSRRLIEQVM 557

Query: 232 NSYYLVSLVDNNY-INGDIFSVF 167
           +++YLV++V+N++    DIF++F
Sbjct: 558 DTWYLVNIVNNDFHKTHDIFNLF 580

[103][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
           dermatitidis ER-3 RepID=C5GPB7_AJEDR
          Length = 633

 Score =  125 bits (313), Expect = 3e-27
 Identities = 63/143 (44%), Positives = 91/143 (63%), Gaps = 1/143 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 413
           S  P  GWG   GYVYQKAYLE   S   +D ++ + +    +TY  VNK     +NT +
Sbjct: 440 SSHPIYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNSDLTYYCVNKKGELKTNTTD 499

Query: 412 SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
           S  NAVTWG+F +KE+IQPTIV+  SF  WKDEA+ +    WA  +     SR+L+E+V 
Sbjct: 500 SP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHAPSSLSRRLIEQVM 557

Query: 232 NSYYLVSLVDNNY-INGDIFSVF 167
           +++YLV++V+N++    DIF++F
Sbjct: 558 DTWYLVNIVNNDFHKTHDIFNLF 580

[104][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
           RepID=B8NG74_ASPFN
          Length = 612

 Score =  124 bits (312), Expect = 4e-27
 Identities = 63/144 (43%), Positives = 92/144 (63%), Gaps = 1/144 (0%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS  P  GWG   G+VYQKAYLE       LD L+ + +    +TY AV+K+    +NT 
Sbjct: 439 KSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIEGNEDLTYHAVSKNGELRTNTH 498

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           +S  NA+TWG+F  +EV+QPTIV+  SF  WKDEA+ +    WA  +    PSRKL++ +
Sbjct: 499 DSP-NALTWGIFAGREVVQPTIVETISFLAWKDEAYRL-GEDWAKCHAATSPSRKLIQGL 556

Query: 235 KNSYYLVSLVDNNYING-DIFSVF 167
            +S+YLV++V+N++ N  D+F +F
Sbjct: 557 VDSWYLVNIVNNDFHNTYDLFELF 580

[105][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
           NIH2624 RepID=Q0CXY7_ASPTN
          Length = 619

 Score =  124 bits (310), Expect = 7e-27
 Identities = 61/144 (42%), Positives = 93/144 (64%), Gaps = 1/144 (0%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           +S  P  GWG   G+VYQKAYLE       LD L+ + +    +TY AV+K+    +NT 
Sbjct: 439 RSSHPVYGWGPKNGFVYQKAYLELLVPPYLLDELIARIEKNEDLTYHAVSKTGELRTNTR 498

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           +S  NA+TWG+F  +EV+QPTIV+  SF  WKDEA+ +    WA  +    PSRKL+++V
Sbjct: 499 DSP-NALTWGIFAGREVVQPTIVETISFLAWKDEAYRL-GEDWAKCHEAGSPSRKLIQDV 556

Query: 235 KNSYYLVSLVDNNYING-DIFSVF 167
            +++YLV++V+N++ N  ++F +F
Sbjct: 557 MDNWYLVNIVNNDFHNSFNLFELF 580

[106][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
           513.88 RepID=A2QCE3_ASPNC
          Length = 626

 Score =  121 bits (304), Expect = 4e-26
 Identities = 60/144 (41%), Positives = 92/144 (63%), Gaps = 1/144 (0%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS  P  GWG   GYVYQKAYLE       +D L+ + +    +TY AV+K+    +NT 
Sbjct: 439 KSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNGDLTYHAVSKTGELRTNTR 498

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           +S  NA+TWG+F  +E++QPTIV+  SF  WKDEA+ +    WA  +    PSRKL++ V
Sbjct: 499 DSP-NALTWGIFAGREIVQPTIVETVSFLAWKDEAYRL-GDDWAKCHDTSSPSRKLIQGV 556

Query: 235 KNSYYLVSLVDNNYIN-GDIFSVF 167
            ++++LV++V+N++ N  ++F +F
Sbjct: 557 MDNWHLVNIVNNDFHNTSNLFDLF 580

[107][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
           Wisconsin 54-1255 RepID=B6H6J4_PENCW
          Length = 610

 Score =  121 bits (303), Expect = 5e-26
 Identities = 59/144 (40%), Positives = 88/144 (61%), Gaps = 1/144 (0%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS  P  GWG   G+VYQKAYLE     + +D L+ + +    +TY A NK     +NT 
Sbjct: 439 KSSHPVYGWGPKNGFVYQKAYLELLVPSNLIDELITRIEKNDDLTYHATNKKGELKTNTR 498

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           +S  NA+TWG+F  +E+IQPTIV+  SF  WKDEA+ +    W+  +    PSR+L++ V
Sbjct: 499 DSP-NALTWGIFAGREIIQPTIVETVSFLAWKDEAY-LLGEHWSKCHDAASPSRQLIQHV 556

Query: 235 KNSYYLVSLVDNNYINGD-IFSVF 167
              +YLV++VDN++   + +F +F
Sbjct: 557 MEDWYLVNIVDNDFHRSNAVFELF 580

[108][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
           pombe RepID=MTHR2_SCHPO
          Length = 641

 Score =  121 bits (303), Expect = 5e-26
 Identities = 55/135 (40%), Positives = 84/135 (62%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 413
           S  P  GWG  GG V+QKA++E F +   L   + K    P +TY A N    +++N  +
Sbjct: 496 SADPVFGWGPKGGRVFQKAFVECFVNGKDLKDFITKWHDNPQVTYYAGNNKSEFLTNAPK 555

Query: 412 SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
              +AVTWGV+P +E+IQ TI+   SFK W  E+F++W   WANLY ++ PSRKLLE   
Sbjct: 556 DGASAVTWGVYPGREIIQSTIIAEVSFKAWLSESFQVWG-EWANLYSKNTPSRKLLENCI 614

Query: 232 NSYYLVSLVDNNYIN 188
           N  +LV+++ +++++
Sbjct: 615 NDRWLVTVIHHDFMD 629

[109][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
           MYA-3404 RepID=C5M851_CANTT
          Length = 609

 Score =  120 bits (300), Expect = 1e-25
 Identities = 59/154 (38%), Positives = 91/154 (59%), Gaps = 16/154 (10%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS---------ITYMAVNK 443
           +S     GWG   GYVYQK YLEFFC KD +  L++    +           I+Y AVNK
Sbjct: 444 RSSDKVFGWGPKNGYVYQKQYLEFFCHKDVVARLLDHIDQYNKNQGDSTSAVISYYAVNK 503

Query: 442 SENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDD 263
           + N +SN  + D+NAVTWGVFP +E++QPTIV+  SF  WKDE + ++S  W+ +    D
Sbjct: 504 NGNLISNCQDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYTLFS-EWSKISGMFD 562

Query: 262 PSR-------KLLEEVKNSYYLVSLVDNNYINGD 182
             +       +L+ ++  ++ L +LV+N+++ G+
Sbjct: 563 AEKDKIQHFNELMSQITENFVLCNLVNNDFLQGN 596

[110][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
           thermotolerans CBS 6340 RepID=C5E2N6_LACTC
          Length = 599

 Score =  118 bits (296), Expect = 3e-25
 Identities = 61/133 (45%), Positives = 84/133 (63%), Gaps = 3/133 (2%)
 Frame = -2

Query: 577 IGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSN-TGESDVN 401
           +GWG   GYVYQK YLEF   K KL  L +     PS+TY AV+ ++   SN   ++  N
Sbjct: 455 VGWGPNNGYVYQKQYLEFLLPKSKLSQLRDFVNDMPSLTYFAVDSADELHSNHPDDTAAN 514

Query: 400 AVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRK--LLEEVKNS 227
           AVTWG+FP +EV+QPTIV+  SF  WK+E F+I    W  +  E++ S    LLE V + 
Sbjct: 515 AVTWGIFPGREVLQPTIVEKVSFLAWKEEFFDILD-EWKRIMGENNHSESVALLESVISD 573

Query: 226 YYLVSLVDNNYIN 188
           Y LV++VDN+Y++
Sbjct: 574 YLLVNIVDNDYVS 586

[111][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
           okayama7#130 RepID=A8NEV2_COPC7
          Length = 617

 Score =  118 bits (296), Expect = 3e-25
 Identities = 59/144 (40%), Positives = 85/144 (59%), Gaps = 2/144 (1%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS--ITYMAVNKSENWVSNT 419
           S     GWG   GYV+QK ++EFFC    ++ + ++ K   +  + Y   N +    SN 
Sbjct: 466 SSDETFGWGPRAGYVFQKGFVEFFCDFHDVEAIEQRIKQRGAGWVHYFMANNNGECRSNV 525

Query: 418 GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEE 239
            E   NAVTWGVFP +E+ Q TI++  SF  WKDEA++IW+ SWA+LY  D   R+LL++
Sbjct: 526 PEDGRNAVTWGVFPGQEIQQTTIIEKESFLTWKDEAYDIWN-SWASLYHPDSAERQLLQK 584

Query: 238 VKNSYYLVSLVDNNYINGDIFSVF 167
           V N  +LVS+V + Y N +    F
Sbjct: 585 VANERWLVSIVHHEYKNPNALWTF 608

[112][TOP]
>UniRef100_UPI000151BABB hypothetical protein PGUG_04648 n=1 Tax=Pichia guilliermondii ATCC
           6260 RepID=UPI000151BABB
          Length = 355

 Score =  118 bits (295), Expect = 4e-25
 Identities = 63/165 (38%), Positives = 94/165 (56%), Gaps = 22/165 (13%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS--------ITYMAVNKS 440
           KS+    GWG   GYV+QK YLEFFC +D    L+E  + F          +TY A +K+
Sbjct: 184 KSNDKVYGWGPKNGYVFQKQYLEFFCHRDIFPKLLESIEKFNEKGGESCSFLTYYAADKN 243

Query: 439 ENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLY----P 272
               +NT E D+NAVTWGVFP +E++QPTIV+  SF  WKDE + + +  W ++Y     
Sbjct: 244 GELNTNTKEDDINAVTWGVFPGEEILQPTIVEKTSFFAWKDEVYRLLA-EWGSVYDSHIT 302

Query: 271 EDDPSRK--------LLEEVKNSYYLVSLVDNNYINGD--IFSVF 167
            D+  +K         L E  + + L ++V+NN+++ D  +FS+F
Sbjct: 303 SDETLKKSQVKEFTHTLNEFADQFILCNIVNNNFVDDDLVLFSIF 347

[113][TOP]
>UniRef100_A5DMZ7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
           RepID=A5DMZ7_PICGU
          Length = 355

 Score =  118 bits (295), Expect = 4e-25
 Identities = 63/165 (38%), Positives = 94/165 (56%), Gaps = 22/165 (13%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS--------ITYMAVNKS 440
           KS+    GWG   GYV+QK YLEFFC +D    L+E  + F          +TY A +K+
Sbjct: 184 KSNDKVYGWGPKNGYVFQKQYLEFFCHRDIFPKLLESIEKFNEKGGESCSFLTYYAADKN 243

Query: 439 ENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLY----P 272
               +NT E D+NAVTWGVFP +E++QPTIV+  SF  WKDE + + +  W ++Y     
Sbjct: 244 GELNTNTKEDDINAVTWGVFPGEEILQPTIVEKTSFFAWKDEVYRLLA-EWGSVYDSHIT 302

Query: 271 EDDPSRK--------LLEEVKNSYYLVSLVDNNYINGD--IFSVF 167
            D+  +K         L E  + + L ++V+NN+++ D  +FS+F
Sbjct: 303 SDETLKKSQVKEFTHTLNEFADQFILCNIVNNNFVDDDSVLFSIF 347

[114][TOP]
>UniRef100_Q6FNS2 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
           RepID=Q6FNS2_CANGA
          Length = 645

 Score =  117 bits (294), Expect = 5e-25
 Identities = 58/140 (41%), Positives = 83/140 (59%), Gaps = 3/140 (2%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF---PSITYMAVNKSENWVSN 422
           S     GWG   G+VYQKA++E F  + +  T+++    +      +Y A +   ++ +N
Sbjct: 499 STDKIFGWGPSKGHVYQKAFIEMFVHRQQWKTILKPKLDYYGRRKFSYYAGDSKGSFETN 558

Query: 421 TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
                 N VTWGVFP  +VIQ TI++  SFK W+DEAF IWS  WA L+P + PS  LL 
Sbjct: 559 LDPHSSNVVTWGVFPNSQVIQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPSNTLLR 617

Query: 241 EVKNSYYLVSLVDNNYINGD 182
           EV + YYLVS+V +++I  D
Sbjct: 618 EVHSDYYLVSIVHHDFIETD 637

[115][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
           CD36 RepID=B9WDQ7_CANDC
          Length = 614

 Score =  117 bits (294), Expect = 5e-25
 Identities = 59/155 (38%), Positives = 94/155 (60%), Gaps = 17/155 (10%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF---------PSITYMAVNK 443
           KS     GWG   GYVYQK YLEFFC KD +  L+++ + F           I+Y AV+K
Sbjct: 444 KSSEKVFGWGPKNGYVYQKQYLEFFCHKDVVSKLLDQVEEFNIKGAESSSAFISYYAVDK 503

Query: 442 SENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI---WSRSWANLYP 272
             N  +N  + D+NAVTWGVFP +E++QPTIV+  SF  WKDE + +   W++  ++   
Sbjct: 504 DGNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFTEWAKIASSNLV 563

Query: 271 EDDPSR-----KLLEEVKNSYYLVSLVDNNYINGD 182
           E D ++     +L+++  + + L +LV+N++++G+
Sbjct: 564 EADQTQVNEFVRLMKKFGDEFVLCNLVNNDFVDGN 598

[116][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
           RepID=Q5AEI0_CANAL
          Length = 614

 Score =  117 bits (293), Expect = 7e-25
 Identities = 62/158 (39%), Positives = 92/158 (58%), Gaps = 20/158 (12%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLV-----------EKSKAFPSITYMAV 449
           KS     GWG   GYVYQK YLEFFC KD +  L+           E S AF  I+Y AV
Sbjct: 444 KSSEKVFGWGPKNGYVYQKQYLEFFCHKDVVSKLLDHVEEFNVKGAESSSAF--ISYYAV 501

Query: 448 NKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPE 269
           +K  N  +N  + D+NAVTWGVFP +E++QPTIV+  SF  WKDE + +++  WA +   
Sbjct: 502 DKDGNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFT-EWAKIASS 560

Query: 268 D---------DPSRKLLEEVKNSYYLVSLVDNNYINGD 182
           +         D   +L+++  + + L +LV+N++++G+
Sbjct: 561 NLVEANQTQVDEFVQLMKKFGDEFVLCNLVNNDFVDGN 598

[117][TOP]
>UniRef100_C4Y9Q4 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
           ATCC 42720 RepID=C4Y9Q4_CLAL4
          Length = 601

 Score =  116 bits (291), Expect = 1e-24
 Identities = 58/139 (41%), Positives = 84/139 (60%), Gaps = 5/139 (3%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSK---DKLDTLVEKSKAFPSITYMAVNKSENWVSN 422
           S    +GWG   G ++QK+++EFF  K   ++L  L++K  +  +ITY   N      +N
Sbjct: 453 SSDSILGWGPRNGRIFQKSFVEFFVPKTEWERLLRLMDKDISDKTITYFCGNSKGEITTN 512

Query: 421 TGE--SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKL 248
                S   A+TWGVFP+KEV+QPT++D  SF+ W +EAF +W   WA  Y  D PS +L
Sbjct: 513 MPHKSSQRTAITWGVFPSKEVLQPTVIDRQSFQAWNEEAFGLW-LDWARCYAPDSPSYRL 571

Query: 247 LEEVKNSYYLVSLVDNNYI 191
           L  + + YYLVS+V NNY+
Sbjct: 572 LAGIHSDYYLVSIVHNNYL 590

[118][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
           S238N-H82 RepID=B0CSW4_LACBS
          Length = 602

 Score =  116 bits (290), Expect = 2e-24
 Identities = 60/137 (43%), Positives = 81/137 (59%), Gaps = 4/137 (2%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSK--AFPSITYMAVNKSENWV--S 425
           S    +GWG  GGYV+QK ++EFFC +  +D +  + +      + Y A N   +    S
Sbjct: 451 SGDKVVGWGPRGGYVFQKGFVEFFCEEKDMDVIERRVERNGHGWVHYFAGNYKADGECRS 510

Query: 424 NTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLL 245
           N  E   NAVTWGVFP +E+ Q TI++  SF  WKDEAF IWS  WA+ Y      RKLL
Sbjct: 511 NVPEGGRNAVTWGVFPGQEIAQTTIIEKESFLTWKDEAFSIWS-EWASFYRPGSEERKLL 569

Query: 244 EEVKNSYYLVSLVDNNY 194
           E V+N  +LVS+V ++Y
Sbjct: 570 EGVRNERWLVSIVHHDY 586

[119][TOP]
>UniRef100_C5DIA7 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
           thermotolerans CBS 6340 RepID=C5DIA7_LACTC
          Length = 660

 Score =  115 bits (289), Expect = 2e-24
 Identities = 58/140 (41%), Positives = 85/140 (60%), Gaps = 3/140 (2%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP---SITYMAVNKSENWVSN 422
           S     GWG PGGYVYQK+++E F  K + +  + K K  P    ++Y   + +E + +N
Sbjct: 515 STDKIFGWGPPGGYVYQKSFVEMFVHKQQWELEI-KPKLEPLGSKVSYYVGDSAETFYTN 573

Query: 421 TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
              S  + VTWGVFP  EV+Q TIV+  SFK W+DEAF IW   W+ L+P +  S  LL+
Sbjct: 574 LDSSCSSVVTWGVFPNSEVLQTTIVEEESFKAWRDEAFSIW-LEWSKLFPRNSRSNTLLK 632

Query: 241 EVKNSYYLVSLVDNNYINGD 182
           ++   YYLVS+V +++ + D
Sbjct: 633 QMHRDYYLVSIVHHDFSDCD 652

[120][TOP]
>UniRef100_Q6CEM7 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
           RepID=Q6CEM7_YARLI
          Length = 625

 Score =  114 bits (286), Expect = 4e-24
 Identities = 58/139 (41%), Positives = 83/139 (59%), Gaps = 1/139 (0%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWV-SNT 419
           KSD    GWG  GGYV+QK++ EFF S ++   L     A   +    V KS+  V +N 
Sbjct: 479 KSDDNIFGWGPKGGYVFQKSFAEFFISPEQWKKLKPLLDAQEDLVSYYVAKSDKLVDTNV 538

Query: 418 GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEE 239
            E   N VTWGVFP +E++Q TI+   SF  W++EAF IWS  W  LY ++  S KLL++
Sbjct: 539 SERASNGVTWGVFPNREIVQTTIIQEDSFDAWREEAFSIWS-EWRALYKKNTASFKLLDK 597

Query: 238 VKNSYYLVSLVDNNYINGD 182
           + N Y LV+++ ++Y+  D
Sbjct: 598 IINEYLLVTVIHHDYVEED 616

[121][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
           RepID=A3LUC7_PICST
          Length = 613

 Score =  114 bits (286), Expect = 4e-24
 Identities = 63/154 (40%), Positives = 90/154 (58%), Gaps = 18/154 (11%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE------KSKAFPS---ITYMAVNK 443
           KS     GWG   GYVYQK YLEFFC KD L  L+       KS+   S   I+Y AV+K
Sbjct: 444 KSSEKVYGWGPKNGYVYQKQYLEFFCPKDLLPKLLHTIDSYNKSEGDASSSIISYYAVDK 503

Query: 442 SENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED- 266
           + N  +N  + D+NAVTWGVFP +E++QPTIV+  SF  WKDE + +++  W N+   + 
Sbjct: 504 NGNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFT-EWTNILQSNL 562

Query: 265 -DPSR-------KLLEEVKNSYYLVSLVDNNYIN 188
            D  +        L+    N++ L +LV+N++I+
Sbjct: 563 VDADKDKISGFVDLITNFSNNFVLCNLVNNDFID 596

[122][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
           elongisporus RepID=A5DXM5_LODEL
          Length = 618

 Score =  114 bits (285), Expect = 6e-24
 Identities = 61/158 (38%), Positives = 89/158 (56%), Gaps = 20/158 (12%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS---------ITYMAVNK 443
           KS     GWG   GYVYQK YLEFFC KD +  L++    + +         I+Y AV+ 
Sbjct: 445 KSSEKIFGWGPKNGYVYQKQYLEFFCHKDIIVKLLQTIDDYNNNQGDASSAIISYYAVDL 504

Query: 442 SENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSR-------SWA 284
             N  +N  + D+NAVTWGVFP +E++QPTIV+  SF  WKDE + ++S        + A
Sbjct: 505 KGNLTTNCNDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFSEWRKVLTSNLA 564

Query: 283 NLYPEDDPS----RKLLEEVKNSYYLVSLVDNNYINGD 182
           ++  ED  +     KL+ E    Y L +LV+N++I+ +
Sbjct: 565 DVKDEDKKNLHKFEKLMTEFSEDYVLCNLVNNDFIDSN 602

[123][TOP]
>UniRef100_Q0UB79 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
           RepID=Q0UB79_PHANO
          Length = 543

 Score =  114 bits (284), Expect = 8e-24
 Identities = 53/138 (38%), Positives = 82/138 (59%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           +S  P  GWG   GYV+QK ++EFF    +   L  +  A   +TY A N + ++ +++ 
Sbjct: 400 RSTDPVFGWGPKNGYVFQKPFVEFFLPAAEFHALRTRLDAHDQVTYFAGNANGDFEASSE 459

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           ES VN VTWG F  KE++ PTI++  SF+ W +EAF IW R W  +YP    S KLL + 
Sbjct: 460 ES-VNPVTWGTFAGKEIVTPTIIEAVSFRSWLEEAFSIW-REWQRIYPTKSASGKLLGQT 517

Query: 235 KNSYYLVSLVDNNYINGD 182
           +   +LV+++  +++ GD
Sbjct: 518 REDVWLVNVIWGDFVQGD 535

[124][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
           RepID=Q75EA7_ASHGO
          Length = 603

 Score =  113 bits (283), Expect = 1e-23
 Identities = 61/138 (44%), Positives = 82/138 (59%), Gaps = 4/138 (2%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKA-FPSITYMAVNKSENWVSN-T 419
           S  P +GWG   GYVYQK YLEF   K  L        A FP++TY AV+  +N  SN  
Sbjct: 453 SADPIVGWGPANGYVYQKQYLEFLLPKHHLPAFHAALTADFPTLTYFAVDADDNLASNHP 512

Query: 418 GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDD--PSRKLL 245
            ++  NAVTWG+FP +EV+QPTIV+ ASF  WKDE + I    W   + E+    S  LL
Sbjct: 513 DDTQANAVTWGIFPGREVLQPTIVEKASFLAWKDEFYRILD-DWRLSFDENGAADSAALL 571

Query: 244 EEVKNSYYLVSLVDNNYI 191
             + + Y LV++VDN+++
Sbjct: 572 AHLTSDYALVNIVDNDFV 589

[125][TOP]
>UniRef100_UPI000023F2EE hypothetical protein FG07127.1 n=1 Tax=Gibberella zeae PH-1
           RepID=UPI000023F2EE
          Length = 672

 Score =  113 bits (282), Expect = 1e-23
 Identities = 57/151 (37%), Positives = 86/151 (56%), Gaps = 13/151 (8%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEK---SKAFPSITYMAVNKSENWVS 425
           +S     GWG P G+V+QK+++EFF   ++ + L  K   S+    + + A N   ++VS
Sbjct: 515 RSSDATFGWGPPNGFVFQKSFVEFFIPANEWEILKAKLVSSELQDYVCFYASNARGDYVS 574

Query: 424 NT----------GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLY 275
           +                NAVTWGVFP KE+I PTI++  SF+ W +EAF IW   WA +Y
Sbjct: 575 SDIGGHVDGSTEASPSTNAVTWGVFPGKEIITPTIIEEVSFRAWCEEAFGIWG-EWAKVY 633

Query: 274 PEDDPSRKLLEEVKNSYYLVSLVDNNYINGD 182
                S KLL  +K+ Y+LV+L+ ++Y+N D
Sbjct: 634 GRGSESEKLLNGIKDDYWLVNLIHHDYVNRD 664

[126][TOP]
>UniRef100_C7YTQ6 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
           RepID=C7YTQ6_NECH7
          Length = 674

 Score =  113 bits (282), Expect = 1e-23
 Identities = 58/151 (38%), Positives = 86/151 (56%), Gaps = 13/151 (8%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEK---SKAFPSITYMAVNKSENWVS 425
           +S     GWG P G+V+QK+++EFF    +   L EK   S+   S+ + A N   ++VS
Sbjct: 517 RSSDGTFGWGPPNGFVFQKSFVEFFIPSSEWSVLKEKLNSSELCDSVCFYAGNAKGDFVS 576

Query: 424 NTGESDV----------NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLY 275
           +     V          NAVTWGVFP KE+I PTI++  SF+ W +EAF IW   WA +Y
Sbjct: 577 SDKGGHVDGSSGAGPSTNAVTWGVFPGKEIITPTIIEEVSFRAWCEEAFGIWG-EWAKVY 635

Query: 274 PEDDPSRKLLEEVKNSYYLVSLVDNNYINGD 182
                S KLL  +K+ Y+LV+L+ ++++  D
Sbjct: 636 GRGSDSEKLLSGIKDEYWLVNLIHHDFVEKD 666

[127][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
          Length = 600

 Score =  112 bits (281), Expect = 2e-23
 Identities = 58/140 (41%), Positives = 86/140 (61%), Gaps = 2/140 (1%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           +S+    GWG   GYVYQK YLEF   K KL  L++  K    +TY A++   + +SN  
Sbjct: 451 RSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHP 510

Query: 415 E-SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDP-SRKLLE 242
           + S  NAVTWG+FP +E++QPTIV+  SF  WK+E + I +    N+   D P S + ++
Sbjct: 511 DNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFYHILNEWKLNMNKYDKPHSAQFIQ 570

Query: 241 EVKNSYYLVSLVDNNYINGD 182
            + + Y LV++VDN+YI+ D
Sbjct: 571 SLIDDYCLVNIVDNDYISPD 590

[128][TOP]
>UniRef100_B5VIK4 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
           cerevisiae AWRI1631 RepID=B5VIK4_YEAS6
          Length = 411

 Score =  112 bits (281), Expect = 2e-23
 Identities = 58/140 (41%), Positives = 86/140 (61%), Gaps = 2/140 (1%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           +S+    GWG   GYVYQK YLEF   K KL  L++  K    +TY A++   + +SN  
Sbjct: 262 RSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHP 321

Query: 415 E-SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDP-SRKLLE 242
           + S  NAVTWG+FP +E++QPTIV+  SF  WK+E + I +    N+   D P S + ++
Sbjct: 322 DNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFYHILNEWKLNMNKYDKPHSAQFIQ 381

Query: 241 EVKNSYYLVSLVDNNYINGD 182
            + + Y LV++VDN+YI+ D
Sbjct: 382 SLIDDYCLVNIVDNDYISPD 401

[129][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
           cerevisiae RM11-1a RepID=B3LHI5_YEAS1
          Length = 600

 Score =  112 bits (281), Expect = 2e-23
 Identities = 58/140 (41%), Positives = 86/140 (61%), Gaps = 2/140 (1%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           +S+    GWG   GYVYQK YLEF   K KL  L++  K    +TY A++   + +SN  
Sbjct: 451 RSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHP 510

Query: 415 E-SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDP-SRKLLE 242
           + S  NAVTWG+FP +E++QPTIV+  SF  WK+E + I +    N+   D P S + ++
Sbjct: 511 DNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFYHILNEWKLNMNKYDKPHSAQFIQ 570

Query: 241 EVKNSYYLVSLVDNNYINGD 182
            + + Y LV++VDN+YI+ D
Sbjct: 571 SLIDDYCLVNIVDNDYISPD 590

[130][TOP]
>UniRef100_B2B6X0 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
           RepID=B2B6X0_PODAN
          Length = 691

 Score =  112 bits (281), Expect = 2e-23
 Identities = 54/151 (35%), Positives = 88/151 (58%), Gaps = 13/151 (8%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSK---AFPSITYMAVNKSENWVS 425
           +S  P  GWG   G+V+QKA++EFF        L +K +       + + A+N + ++VS
Sbjct: 534 RSSDPTFGWGPANGFVFQKAFVEFFIPSADWKVLEQKLRHPDLKDDVCFYAINAAGDFVS 593

Query: 424 NTG----------ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLY 275
           +            E+  NAVTWGVFP KE++ PTI++  SF+ W +EAF IW   WA +Y
Sbjct: 594 SDTAGSLEAEGEKEASTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWG-EWAKIY 652

Query: 274 PEDDPSRKLLEEVKNSYYLVSLVDNNYINGD 182
            +   S KLLE+++   +LV+++ +++I+ D
Sbjct: 653 GKGSESEKLLEKIRGDSWLVNIIHHDFIDSD 683

[131][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
           cerevisiae RepID=MTHR2_YEAST
          Length = 600

 Score =  112 bits (281), Expect = 2e-23
 Identities = 58/140 (41%), Positives = 86/140 (61%), Gaps = 2/140 (1%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           +S+    GWG   GYVYQK YLEF   K KL  L++  K    +TY A++   + +SN  
Sbjct: 451 RSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHP 510

Query: 415 E-SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDP-SRKLLE 242
           + S  NAVTWG+FP +E++QPTIV+  SF  WK+E + I +    N+   D P S + ++
Sbjct: 511 DNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFYHILNEWKLNMNKYDKPHSAQFIQ 570

Query: 241 EVKNSYYLVSLVDNNYINGD 182
            + + Y LV++VDN+YI+ D
Sbjct: 571 SLIDDYCLVNIVDNDYISPD 590

[132][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
           NRRL 181 RepID=A1CZX0_NEOFI
          Length = 716

 Score =  112 bits (280), Expect = 2e-23
 Identities = 57/150 (38%), Positives = 84/150 (56%), Gaps = 16/150 (10%)
 Frame = -2

Query: 595 KSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSENWV 428
           +SD P  GWG PG G+V+QK ++EFFC      T+++   A      + + A N    + 
Sbjct: 542 RSDDPTFGWGPPGEGFVFQKPFVEFFCPSKDFQTVLKPLFAKHGHEKLAWFATNVKGEFE 601

Query: 427 SNT------------GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWA 284
           S+               ++VNAVTWGVF  KE++ PTI++  SF+ W +EAF IW   W 
Sbjct: 602 SSLPADPAHADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EWR 660

Query: 283 NLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
            +YP   P+ +LLEEVKN  +LV +V  ++
Sbjct: 661 RVYPRGTPTERLLEEVKNDVWLVCVVGQDF 690

[133][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
           japonicus yFS275 RepID=B6K4Z7_SCHJY
          Length = 605

 Score =  112 bits (279), Expect = 3e-23
 Identities = 59/134 (44%), Positives = 80/134 (59%), Gaps = 1/134 (0%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 413
           S  P  GWG   GYV+QKAYLEFF   D++ +L+E   +F ++ Y  +   E  +   GE
Sbjct: 448 STDPLFGWGPAHGYVFQKAYLEFFMHPDQVKSLLEVIPSFKTVQYY-ITDYEGSLETNGE 506

Query: 412 SDV-NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
            DV +AVTWGVFP  EVIQPT+V+ ASF  WKDEA+ +   SWA  +       KLL  +
Sbjct: 507 LDVPSAVTWGVFPNSEVIQPTVVESASFLAWKDEAYSL-GLSWAKAHSSTSAPFKLLTNI 565

Query: 235 KNSYYLVSLVDNNY 194
              + L  +VDN++
Sbjct: 566 VKEWKLCVIVDNDF 579

[134][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
           CBS767 RepID=UPI00003BE4A8
          Length = 617

 Score =  111 bits (278), Expect = 4e-23
 Identities = 59/157 (37%), Positives = 85/157 (54%), Gaps = 21/157 (13%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS---------ITYMAVNK 443
           KS+    GWG   GYVYQK YLEFF  KD +  L+ +   +           +TY AV++
Sbjct: 444 KSNDKVYGWGPKNGYVYQKQYLEFFVHKDIIPALLHQIDNYNRGQGDSNSSVLTYYAVDQ 503

Query: 442 SENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED- 266
                SNT + D+NAVTWGVFP +E++QPTIV+  SF  WKDE + + +  W  ++  D 
Sbjct: 504 KGKLFSNTKDDDINAVTWGVFPGEEILQPTIVEKVSFLAWKDEVYRLIT-EWIKIFQSDF 562

Query: 265 -----------DPSRKLLEEVKNSYYLVSLVDNNYIN 188
                      D   KL+    + Y L ++V+NN+I+
Sbjct: 563 VKDVNITKEDVDAFVKLMTNFNDEYVLCNVVNNNFID 599

[135][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
           RepID=Q4WEL9_ASPFU
          Length = 689

 Score =  111 bits (278), Expect = 4e-23
 Identities = 57/150 (38%), Positives = 84/150 (56%), Gaps = 16/150 (10%)
 Frame = -2

Query: 595 KSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSENWV 428
           +SD P  GWG PG G+V+QK ++EFFC      T+++   A      + + A N    + 
Sbjct: 515 RSDDPTFGWGPPGEGFVFQKPFVEFFCPSKDFRTVLKPLFAKHGHEKLAWFATNVKGEFE 574

Query: 427 SNT------------GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWA 284
           S+               ++VNAVTWGVF  KE++ PTI++  SF+ W +EAF IW   W 
Sbjct: 575 SSLPADPAHADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EWR 633

Query: 283 NLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
            +YP   P+ +LLEEVKN  +LV +V  ++
Sbjct: 634 RVYPRGTPTERLLEEVKNDVWLVCVVGQDF 663

[136][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
           RepID=B5RV11_DEBHA
          Length = 617

 Score =  111 bits (278), Expect = 4e-23
 Identities = 59/157 (37%), Positives = 85/157 (54%), Gaps = 21/157 (13%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS---------ITYMAVNK 443
           KS+    GWG   GYVYQK YLEFF  KD +  L+ +   +           +TY AV++
Sbjct: 444 KSNDKVYGWGPKNGYVYQKQYLEFFVHKDIIPALLHQIDNYNRGQGDSNSSVLTYYAVDQ 503

Query: 442 SENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED- 266
                SNT + D+NAVTWGVFP +E++QPTIV+  SF  WKDE + + +  W  ++  D 
Sbjct: 504 KGKLFSNTKDDDINAVTWGVFPGEEILQPTIVEKVSFLAWKDEVYRLIT-EWIKIFQSDF 562

Query: 265 -----------DPSRKLLEEVKNSYYLVSLVDNNYIN 188
                      D   KL+    + Y L ++V+NN+I+
Sbjct: 563 VKDVNITKEDVDAFVKLMTNFNDEYVLCNVVNNNFID 599

[137][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
           A1163 RepID=B0Y2U3_ASPFC
          Length = 689

 Score =  111 bits (278), Expect = 4e-23
 Identities = 57/150 (38%), Positives = 84/150 (56%), Gaps = 16/150 (10%)
 Frame = -2

Query: 595 KSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSENWV 428
           +SD P  GWG PG G+V+QK ++EFFC      T+++   A      + + A N    + 
Sbjct: 515 RSDDPTFGWGPPGEGFVFQKPFVEFFCPSKDFRTVLKPLFAKHGHEKLAWFATNVKGEFE 574

Query: 427 SNT------------GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWA 284
           S+               ++VNAVTWGVF  KE++ PTI++  SF+ W +EAF IW   W 
Sbjct: 575 SSLPADPAHADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EWR 633

Query: 283 NLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
            +YP   P+ +LLEEVKN  +LV +V  ++
Sbjct: 634 RVYPRGTPTERLLEEVKNDVWLVCVVGQDF 663

[138][TOP]
>UniRef100_Q5A5S8 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
           RepID=Q5A5S8_CANAL
          Length = 640

 Score =  110 bits (276), Expect = 6e-23
 Identities = 56/141 (39%), Positives = 82/141 (58%), Gaps = 5/141 (3%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS     GWG   G +YQK+++E F  K+    L+ K +   ++TY   NK     SN  
Sbjct: 490 KSTDNIFGWGPRNGIIYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVGNKDGEIKSNLP 549

Query: 415 -----ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRK 251
                +   NAVTWGVFP+KEV+QPT++D  SFK W +EAF +W   WA  Y ++  S +
Sbjct: 550 IGPNVKLSKNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFLLW-LEWARCYKKNSKSFE 608

Query: 250 LLEEVKNSYYLVSLVDNNYIN 188
           LL  +  +Y LVS++ +++IN
Sbjct: 609 LLNSIYENYVLVSMIHHDFIN 629

[139][TOP]
>UniRef100_C4YKV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
           RepID=C4YKV3_CANAL
          Length = 640

 Score =  110 bits (276), Expect = 6e-23
 Identities = 56/141 (39%), Positives = 82/141 (58%), Gaps = 5/141 (3%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS     GWG   G +YQK+++E F  K+    L+ K +   ++TY   NK     SN  
Sbjct: 490 KSTDNIFGWGPRNGIIYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVGNKDGEIKSNLP 549

Query: 415 -----ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRK 251
                +   NAVTWGVFP+KEV+QPT++D  SFK W +EAF +W   WA  Y ++  S +
Sbjct: 550 IGPNVKLSKNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFLLW-LEWARCYKKNSKSFE 608

Query: 250 LLEEVKNSYYLVSLVDNNYIN 188
           LL  +  +Y LVS++ +++IN
Sbjct: 609 LLNSIYENYVLVSMIHHDFIN 629

[140][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
           ATCC 42720 RepID=C4Y415_CLAL4
          Length = 614

 Score =  110 bits (276), Expect = 6e-23
 Identities = 62/150 (41%), Positives = 90/150 (60%), Gaps = 16/150 (10%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTL---VEKSKA---FPSITYMAVNKSEN 434
           +S+    GWG   G+VYQK YLEF   KDKL  L   VEK  A   +  ITY AV+KS N
Sbjct: 446 RSNDKLYGWGPKNGFVYQKQYLEFLVRKDKLKELLDIVEKHNAKDTYGLITYYAVDKSGN 505

Query: 433 WVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI---W-----SRSWANL 278
             +N+   D+NAVTWGVFP +E++QPTIV+  SF  WKDE + +   W     S++  ++
Sbjct: 506 LHTNSKNDDINAVTWGVFPGEEILQPTIVEKVSFLAWKDEVYSLLDEWITIFHSKAITDI 565

Query: 277 YPEDDPSR--KLLEEVKNSYYLVSLVDNNY 194
            PED  ++   L++    ++ L + V+N++
Sbjct: 566 VPEDKINKFDDLIKSFGENFVLCNFVNNDF 595

[141][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
           rouxii CBS 732 RepID=C5E412_ZYGRC
          Length = 599

 Score =  110 bits (274), Expect = 1e-22
 Identities = 61/140 (43%), Positives = 83/140 (59%), Gaps = 4/140 (2%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS  P  GWG   GYVYQK YLEF   K+KL  L +       +TY AV+ + N  +N  
Sbjct: 450 KSSHPVHGWGPRDGYVYQKMYLEFLLPKEKLSKLHDCLVNDVMLTYFAVDHNGNLTTNHQ 509

Query: 415 ESD-VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI---WSRSWANLYPEDDPSRKL 248
           +    NAVTWG+FP +EV+QPTIV+  SF  WK E + I   W  ++ N     D S KL
Sbjct: 510 DGTRANAVTWGIFPGREVLQPTIVEKVSFLAWKQEFYHICEEWKLNFIN--HRCDQSVKL 567

Query: 247 LEEVKNSYYLVSLVDNNYIN 188
           L+ + + Y LV++VDN++I+
Sbjct: 568 LQHLIDDYVLVNIVDNDFIS 587

[142][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
           RepID=Q6FU20_CANGA
          Length = 600

 Score =  109 bits (273), Expect = 1e-22
 Identities = 58/147 (39%), Positives = 91/147 (61%), Gaps = 5/147 (3%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           +S+    GWG   GYVYQK YLEF    +K++ L ++      +TY AV+  +N  SN  
Sbjct: 451 RSNHKVHGWGPKDGYVYQKQYLEFLLPNEKVEKLEKQLAGNEMLTYFAVDNKDNLKSNHP 510

Query: 415 E-SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDD--PSRKLL 245
           + S  NAVTWG+FP +EV+QPTIV+  SF  WK+E + I    W   + E++   S + +
Sbjct: 511 DGSKANAVTWGIFPGREVLQPTIVEKVSFLAWKEEFYRI-LEEWKWNFQENNELKSAEFI 569

Query: 244 EEVKNSYYLVSLVDNNYING--DIFSV 170
           + + ++Y LV++VDN+YI+   +I++V
Sbjct: 570 QHIIDNYMLVNIVDNDYISSTDEIYNV 596

[143][TOP]
>UniRef100_C5GI01 Methylenetetrahydrofolate reductase n=2 Tax=Ajellomyces dermatitidis
            RepID=C5GI01_AJEDR
          Length = 713

 Score =  109 bits (273), Expect = 1e-22
 Identities = 56/162 (34%), Positives = 89/162 (54%), Gaps = 28/162 (17%)
 Frame = -2

Query: 595  KSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWV 428
            ++D P  GWG  G G+V+QKA++EFFC+   L T+++   ++     + + A N + ++ 
Sbjct: 519  RNDHPIFGWGPRGEGFVFQKAFVEFFCTAHDLKTILKPIFENHGHDELAWFATNAAGDFE 578

Query: 427  SNTGESD------------------------VNAVTWGVFPAKEVIQPTIVDPASFKVWK 320
            S++  +D                        VNAVTWGVF  KE++ PTI++  SF+ W 
Sbjct: 579  SSSPPTDDSANDYSGPVDVYLDSNATAGGTGVNAVTWGVFRGKEIVTPTIIEEVSFRAWG 638

Query: 319  DEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
            DEAF IW   W  ++P   P+ KLL+++KN  +LV +V   Y
Sbjct: 639  DEAFRIWD-EWRRVFPRGSPTEKLLDQLKNDVWLVCVVGQKY 679

[144][TOP]
>UniRef100_B2WHR5 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
           tritici-repentis Pt-1C-BFP RepID=B2WHR5_PYRTR
          Length = 653

 Score =  109 bits (273), Expect = 1e-22
 Identities = 52/138 (37%), Positives = 79/138 (57%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS  P  GWG   GYV+QK ++EFF    +      K +A   +T+ A N +  + ++  
Sbjct: 510 KSTDPIFGWGPKNGYVFQKPFVEFFIPAAEFQAFKPKLQAHDQVTWFAGNAAGAFEASQ- 568

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           E  VN VTWG F  KE++ PTI++  SF+ W DEAF IW + W  +YP    S  LL E+
Sbjct: 569 EDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWLDEAFSIW-KEWQRIYPPRSGSSVLLGEL 627

Query: 235 KNSYYLVSLVDNNYINGD 182
               +LV+++  +++NG+
Sbjct: 628 SKDVWLVNVIWGDFVNGE 645

[145][TOP]
>UniRef100_B9WCV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
           CD36 RepID=B9WCV3_CANDC
          Length = 640

 Score =  109 bits (272), Expect = 2e-22
 Identities = 55/141 (39%), Positives = 82/141 (58%), Gaps = 5/141 (3%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSN-- 422
           KS     GWG   G +YQK+++E F  K+    L+ K +   ++TY   +K     SN  
Sbjct: 490 KSTDNIFGWGPRNGTIYQKSFIELFMPKEDWTKLLLKIELDKTVTYYVGDKDGEIRSNLP 549

Query: 421 ---TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRK 251
                +   NAVTWGVFP+KEV+QPT++D  SFK W +EAF +W   WA  Y ++  S +
Sbjct: 550 IGPNAKLSKNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFLLWV-EWARCYKKNSKSFE 608

Query: 250 LLEEVKNSYYLVSLVDNNYIN 188
           LL  +  +Y LVS++ +++IN
Sbjct: 609 LLNSIYENYVLVSIIHHDFIN 629

[146][TOP]
>UniRef100_A7TRT4 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
           polyspora DSM 70294 RepID=A7TRT4_VANPO
          Length = 645

 Score =  108 bits (271), Expect = 2e-22
 Identities = 58/140 (41%), Positives = 83/140 (59%), Gaps = 3/140 (2%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE-KSKAFP--SITYMAVNKSENWVSN 422
           S     GWG   GYVYQKA++E F  K + + +V+ K   +P    +Y   + S ++ SN
Sbjct: 499 STDKIFGWGPKNGYVYQKAFVEMFILKKQWEAIVKPKLDHYPRGKFSYYVGDSSGSFESN 558

Query: 421 TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
              +  N VTWGVFP   VIQ TIV+  SFK W+DEAF IW   WA L+P ++ S   L+
Sbjct: 559 LETNSSNVVTWGVFPNSPVIQTTIVEEESFKAWRDEAFCIW-LEWAKLFPSNELSNSFLK 617

Query: 241 EVKNSYYLVSLVDNNYINGD 182
           +V ++Y LVS+V +++   D
Sbjct: 618 QVHSTYCLVSIVHHDFSETD 637

[147][TOP]
>UniRef100_Q1DT03 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
            RepID=Q1DT03_COCIM
          Length = 711

 Score =  108 bits (270), Expect = 3e-22
 Identities = 60/163 (36%), Positives = 85/163 (52%), Gaps = 29/163 (17%)
 Frame = -2

Query: 595  KSDSPAIGWGGPG-GYVYQKAYLEFFCSKDK----LDTLVEKSKAFPSITYMAVNKSENW 431
            +SD P  GWG PG G+V+QKA++EFFCSKD     L  L+++        + A N + ++
Sbjct: 521  RSDHPIFGWGPPGEGFVFQKAFVEFFCSKDDYRSHLKPLLQRY-GHDEFAWFATNAAGDF 579

Query: 430  VSNTGES------------------------DVNAVTWGVFPAKEVIQPTIVDPASFKVW 323
             S+T  S                         VNAVTWGVF  KE+I PTI++  SF+ W
Sbjct: 580  ESSTSSSIPVPTGPVDAVFDDMDSFPSSNSGGVNAVTWGVFRGKEIITPTIIEEVSFRAW 639

Query: 322  KDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
             +EAF IW   W  ++P   P+ KLL  VK   +LV ++   +
Sbjct: 640  GEEAFRIWD-EWRRIFPRGSPTEKLLNRVKEDTWLVCVIGQRF 681

[148][TOP]
>UniRef100_Q0CE17 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
           NIH2624 RepID=Q0CE17_ASPTN
          Length = 696

 Score =  108 bits (270), Expect = 3e-22
 Identities = 55/150 (36%), Positives = 84/150 (56%), Gaps = 16/150 (10%)
 Frame = -2

Query: 595 KSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWV 428
           +SD P  GWG P  G+V+QK ++EFFC      T ++   +      + + A N + ++ 
Sbjct: 523 RSDDPIFGWGPPREGFVFQKPFVEFFCPTKDYQTALKPMLQKHGHEKLAWFATNANGDFE 582

Query: 427 SN----TGESD--------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWA 284
           S+    T ++D        VNAVTWGVF  KE++ PTI++  SF+ W DEA+ IW   W 
Sbjct: 583 SSLPAQTSDADPIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWD-EWR 641

Query: 283 NLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
            +YP   P+ + LEE KN  +LV +V  ++
Sbjct: 642 RIYPRGSPTERFLEETKNDVWLVCVVGQDF 671

[149][TOP]
>UniRef100_C5P4Q4 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
            C735 delta SOWgp RepID=C5P4Q4_COCP7
          Length = 711

 Score =  108 bits (270), Expect = 3e-22
 Identities = 60/163 (36%), Positives = 85/163 (52%), Gaps = 29/163 (17%)
 Frame = -2

Query: 595  KSDSPAIGWGGPG-GYVYQKAYLEFFCSKDK----LDTLVEKSKAFPSITYMAVNKSENW 431
            +SD P  GWG PG G+V+QKA++EFFCSKD     L  L+++        + A N + ++
Sbjct: 521  RSDHPIFGWGPPGEGFVFQKAFVEFFCSKDDYRSHLKPLLQRY-GHDEFAWFATNAAGDF 579

Query: 430  VSNTGES------------------------DVNAVTWGVFPAKEVIQPTIVDPASFKVW 323
             S+T  S                         VNAVTWGVF  KE+I PTI++  SF+ W
Sbjct: 580  ESSTSSSIPVPTGPVDAVFDDMDSFPSSNSGGVNAVTWGVFRGKEIITPTIIEEVSFRAW 639

Query: 322  KDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
             +EAF IW   W  ++P   P+ KLL  VK   +LV ++   +
Sbjct: 640  GEEAFRIWD-EWRRIFPRGSPTEKLLNRVKEDTWLVCVIGQRF 681

[150][TOP]
>UniRef100_A5DE00 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
           RepID=A5DE00_PICGU
          Length = 642

 Score =  108 bits (270), Expect = 3e-22
 Identities = 59/143 (41%), Positives = 82/143 (57%), Gaps = 9/143 (6%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDT-LVEKSKAFPS---ITYMAVNKSENWV 428
           +S     GWG   G+V+QK+++E F  K++  T L  K K       ITY A + S    
Sbjct: 489 RSSDKIFGWGPSNGFVFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDITYYAGDSSGKIQ 548

Query: 427 SNT-----GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDD 263
           SN        +  NAVTWGVFP++EV+QPTI+D  SF+ W +EAF +WS  WA  Y ++ 
Sbjct: 549 SNLPVGPDSHNSKNAVTWGVFPSQEVLQPTIIDIESFRAWNEEAFHLWS-EWARCYKKNS 607

Query: 262 PSRKLLEEVKNSYYLVSLVDNNY 194
            S  LL  +   YYLVSL+ +N+
Sbjct: 608 VSYNLLNSINGDYYLVSLIYHNF 630

[151][TOP]
>UniRef100_Q6CR34 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
           RepID=Q6CR34_KLULA
          Length = 649

 Score =  108 bits (269), Expect = 4e-22
 Identities = 53/140 (37%), Positives = 82/140 (58%), Gaps = 2/140 (1%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS--ITYMAVNKSENWVSN 422
           +S     GWG   G +YQKA++E F  K++ + +++      +   +Y   + +  + +N
Sbjct: 503 QSTDNIFGWGPANGLIYQKAFVEIFVRKEEWNQVLKPKIESKNGEFSYYLGDYTGYFETN 562

Query: 421 TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
                 NAVTWGVFP  EV+Q TIV+  SFK W+DEAF IW   W+ L+P++ P    L 
Sbjct: 563 LQPKSSNAVTWGVFPNSEVVQTTIVEEESFKAWRDEAFSIWI-EWSKLFPKNTPENTFLR 621

Query: 241 EVKNSYYLVSLVDNNYINGD 182
           ++   YYLVS+V +++IN D
Sbjct: 622 KMHRDYYLVSIVHHDFINPD 641

[152][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
           RepID=Q6CKM1_KLULA
          Length = 604

 Score =  108 bits (269), Expect = 4e-22
 Identities = 58/139 (41%), Positives = 83/139 (59%), Gaps = 4/139 (2%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS-ITYMAVNKSENWVSNTG 416
           S  P +GWG   GYVYQK YLEF   ++KL    E  +     +TY A++  +N  +N  
Sbjct: 454 STDPVVGWGPTKGYVYQKEYLEFLLPREKLPLFQEICQEHSDHLTYFAIDSQDNLATNHP 513

Query: 415 E-SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED--DPSRKLL 245
           E S  NAVTWGVFP  E++QPTIV+ ASF  WK+E F I  + W   + E     S  L+
Sbjct: 514 EDSRANAVTWGVFPGSEILQPTIVEKASFLAWKEEFFTI-LKEWKLTFVEHKATESVNLV 572

Query: 244 EEVKNSYYLVSLVDNNYIN 188
             + ++Y L+++VDN++I+
Sbjct: 573 NHIIDNYVLINVVDNDFIS 591

[153][TOP]
>UniRef100_C8V780 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
           [Source:UniProtKB/TrEMBL;Acc:Q5AU15] n=2 Tax=Emericella
           nidulans RepID=C8V780_EMENI
          Length = 684

 Score =  108 bits (269), Expect = 4e-22
 Identities = 53/150 (35%), Positives = 83/150 (55%), Gaps = 16/150 (10%)
 Frame = -2

Query: 595 KSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWV 428
           +SD P  GWG PG G+V+QK ++EFFC      T ++   +      + + A N + ++ 
Sbjct: 511 RSDDPIFGWGPPGEGFVFQKPFVEFFCPASDFKTTLKPLLQKHGHEKLAWFATNAAGDFE 570

Query: 427 SNT------------GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWA 284
           S+               ++VNAVTWGVF  KE++ PTI++  SF+ W DEA+ IW   W 
Sbjct: 571 SSLPAETSDTEPVEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWD-EWR 629

Query: 283 NLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
            +YP+   + K LE+ KN  +LV +V  ++
Sbjct: 630 RIYPKSSATEKFLEKTKNDVWLVCVVGQDF 659

[154][TOP]
>UniRef100_A2QUJ5 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
           513.88 RepID=A2QUJ5_ASPNC
          Length = 699

 Score =  108 bits (269), Expect = 4e-22
 Identities = 57/151 (37%), Positives = 86/151 (56%), Gaps = 17/151 (11%)
 Frame = -2

Query: 595 KSDSPAIGWGGPG-GYVYQKAYLEFFC-SKDKLDTL--VEKSKAFPSITYMAVNKSENWV 428
           +SD P  GWG PG G+V+QK ++EFFC +KD L  L  + +      + + A N   ++ 
Sbjct: 524 RSDDPVFGWGPPGEGFVFQKPFVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNVKGDFE 583

Query: 427 S-----NTGESD--------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSW 287
           S     NT + D        VNAVTWGVF  KE++ PTI++  SF+ W DEA+ IW   W
Sbjct: 584 SSLPGPNTDDPDPIDINPANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWD-EW 642

Query: 286 ANLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
             +YP++  + + L++ KN  +LV +V   +
Sbjct: 643 RRIYPKNSATERFLDDTKNDVWLVCVVGQEF 673

[155][TOP]
>UniRef100_Q7S2B6 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
           RepID=Q7S2B6_NEUCR
          Length = 681

 Score =  107 bits (268), Expect = 5e-22
 Identities = 58/163 (35%), Positives = 89/163 (54%), Gaps = 25/163 (15%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSENWVS 425
           +SD    GWG   G+V+QKA++EFF        L  K K      ++ + A N + ++VS
Sbjct: 512 RSDDGTFGWGPENGFVFQKAFVEFFIPSADWRVLEAKLKQPDMKDTVCFFATNAAGDFVS 571

Query: 424 N---------------TGESD-------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 311
                           T E+D        NAVTWGVFP KE++ PTI++  SF+ W +EA
Sbjct: 572 TDTINFRARMAAEAEGTAEADHRPHEPSTNAVTWGVFPGKEILTPTIIEEVSFRAWSEEA 631

Query: 310 FEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNNYINGD 182
           F IWS  WA +Y +   ++KLLE++K   +LV+++ ++Y+  D
Sbjct: 632 FGIWS-EWAKIYGKGSDTQKLLEDLKEDLWLVNVIHHDYLEKD 673

[156][TOP]
>UniRef100_C9S7I3 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
           VaMs.102 RepID=C9S7I3_9PEZI
          Length = 312

 Score =  107 bits (268), Expect = 5e-22
 Identities = 52/113 (46%), Positives = 65/113 (57%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS     GWG   GYVYQK+YLE     D    ++ + +  P +TY AV KS N   N  
Sbjct: 147 KSSHAVHGWGPKNGYVYQKSYLEMLVHPDLYPEIISRIEKHPDMTYYAVTKSGNLKYNAP 206

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 257
               NAVTWGVFP KE++QPTIV+  SF  WKDEAF +    WA+ + +  PS
Sbjct: 207 SDGPNAVTWGVFPGKEIVQPTIVEGISFVAWKDEAFRL-GLDWAHCFEQSSPS 258

[157][TOP]
>UniRef100_A6RQJ7 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
           B05.10 RepID=A6RQJ7_BOTFB
          Length = 663

 Score =  106 bits (265), Expect = 1e-21
 Identities = 51/142 (35%), Positives = 83/142 (58%), Gaps = 4/142 (2%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSENWVS 425
           KS     GWG   G+V+QKA++E F       TL  K  +     ++++ A N   +++S
Sbjct: 515 KSSDSIFGWGPKNGFVFQKAFVELFIPVADWKTLHAKLTSPDLCDTVSFYASNAKGDFIS 574

Query: 424 NT-GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKL 248
           +       NAVTWG FP KE+I PTI++  SF+ W +EAF IW   WA +Y +D  +RK+
Sbjct: 575 SDEAVGSTNAVTWGAFPGKEIITPTIIEEVSFRAWAEEAFGIWG-EWARVYGKDSQTRKI 633

Query: 247 LEEVKNSYYLVSLVDNNYINGD 182
           ++ +K   +LV+++ + Y+ G+
Sbjct: 634 IDGIKEDVWLVNVIHHAYVEGE 655

[158][TOP]
>UniRef100_C5M548 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
           MYA-3404 RepID=C5M548_CANTT
          Length = 633

 Score =  106 bits (264), Expect = 2e-21
 Identities = 57/139 (41%), Positives = 82/139 (58%), Gaps = 5/139 (3%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           KS     GWG   G VYQKA++E F  KD  + L    +A  SITY A +K+    +   
Sbjct: 483 KSTDNIFGWGPRNGVVYQKAFVELFMPKDDWNKLKPLVEASDSITYYAADKTNKIEAKVP 542

Query: 415 ES-DV----NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRK 251
              D+    NAVTWGVFP+KEV+QPT++D  SFK W +E+F +W   W+  Y ++  S +
Sbjct: 543 AGHDIKLTKNAVTWGVFPSKEVLQPTVIDYESFKAWNEESFLLW-LEWSRCYKKNSKSFE 601

Query: 250 LLEEVKNSYYLVSLVDNNY 194
           LL +V  +Y LV L+ +++
Sbjct: 602 LLNKVYENYVLVCLIYHDF 620

[159][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
           polyspora DSM 70294 RepID=A7TTE9_VANPO
          Length = 612

 Score =  106 bits (264), Expect = 2e-21
 Identities = 57/157 (36%), Positives = 89/157 (56%), Gaps = 19/157 (12%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEK----SKAFPSITYMAVNKSENWV 428
           +S+    GWG   GYVYQK YLEF   + + + L ++    ++   S+TY+A +    W 
Sbjct: 446 RSNVKGFGWGPSDGYVYQKQYLEFLLPRARFERLQQELSKTNETTSSLTYLAADSHGGWW 505

Query: 427 SNTGE-SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEI---WSRSWANLYPEDD- 263
           SN  + +   AVTWGVFP +EV+QPTIV+  SF  W+DE + I   W   + +  P+ D 
Sbjct: 506 SNQPDGAKATAVTWGVFPGREVLQPTIVEKISFLAWRDEFYRILQDWRDIFVHASPDGDQ 565

Query: 262 ----------PSRKLLEEVKNSYYLVSLVDNNYINGD 182
                     PS KL++ + + Y LV+L+DN++++ D
Sbjct: 566 CDNGSAQRENPSAKLMQLMIDDYVLVNLIDNDFVSVD 602

[160][TOP]
>UniRef100_A7E9M9 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
           sclerotiorum 1980 UF-70 RepID=A7E9M9_SCLS1
          Length = 663

 Score =  106 bits (264), Expect = 2e-21
 Identities = 52/142 (36%), Positives = 84/142 (59%), Gaps = 4/142 (2%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEK--SKAF-PSITYMAVNKSENWVS 425
           KS     GWG   G+V+QKA++E F      + L  K  S A   ++++ A N   +++S
Sbjct: 515 KSTDSIFGWGPKNGFVFQKAFVELFLPTSDWEALQAKLTSPALRDTVSFYASNAKGDFIS 574

Query: 424 NTGE-SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKL 248
           +       NAVTWG FP KE+I PTI++  SF+ W +EAF IW   WA +Y +D  +RK+
Sbjct: 575 SDEAIGSTNAVTWGAFPGKEIITPTIIEEVSFRAWAEEAFGIWG-EWARVYGKDSETRKV 633

Query: 247 LEEVKNSYYLVSLVDNNYINGD 182
           ++ +K   +LV+++ + Y+ G+
Sbjct: 634 IDGIKEDVWLVNVIHHAYVEGE 655

[161][TOP]
>UniRef100_UPI000151A866 hypothetical protein PGUG_01501 n=1 Tax=Pichia guilliermondii ATCC
           6260 RepID=UPI000151A866
          Length = 642

 Score =  105 bits (262), Expect = 3e-21
 Identities = 58/143 (40%), Positives = 80/143 (55%), Gaps = 9/143 (6%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDT-LVEKSKAFPS---ITYMAVNKSENWV 428
           +S     GWG   G+V+QK+++E F  K++  T L  K K       ITY A + S    
Sbjct: 489 RSSDKIFGWGPSNGFVFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDITYYAGDSSGKIQ 548

Query: 427 SNT-----GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDD 263
           SN        +  NAVTWGVFP +EV+QPTI+D  SF+ W +EAF +W   WA  Y ++ 
Sbjct: 549 SNLPVGPDSHNSKNAVTWGVFPLQEVLQPTIIDIESFRAWNEEAFHLW-LEWARCYKKNS 607

Query: 262 PSRKLLEEVKNSYYLVSLVDNNY 194
            S  LL  +   YYLVSL+ +N+
Sbjct: 608 VSYNLLNSINGDYYLVSLIYHNF 630

[162][TOP]
>UniRef100_Q752W6 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
           RepID=Q752W6_ASHGO
          Length = 635

 Score =  105 bits (262), Expect = 3e-21
 Identities = 50/133 (37%), Positives = 77/133 (57%), Gaps = 2/133 (1%)
 Frame = -2

Query: 574 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS--ITYMAVNKSENWVSNTGESDVN 401
           GWG PGG VYQKA++E F  K + +  ++     P    +Y   + + ++ SN      +
Sbjct: 496 GWGPPGGVVYQKAFVELFVEKARWEAELKPRLEGPDSKFSYYFGDSAGSFASNMAPESSS 555

Query: 400 AVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYY 221
            VTWGVFP  +++Q TI++  SFK W+DEAF IW  SW+ L+P + P    L  +   Y 
Sbjct: 556 VVTWGVFPNSQILQTTIIEEESFKAWRDEAFSIW-LSWSKLFPRNSPHNAFLRGIHRDYC 614

Query: 220 LVSLVDNNYINGD 182
           LVS+V +++ + D
Sbjct: 615 LVSIVHHDFSSVD 627

[163][TOP]
>UniRef100_C0NTN2 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
            G186AR RepID=C0NTN2_AJECG
          Length = 713

 Score =  105 bits (262), Expect = 3e-21
 Identities = 52/162 (32%), Positives = 87/162 (53%), Gaps = 28/162 (17%)
 Frame = -2

Query: 595  KSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWV 428
            ++D P  GWG  G G+V+QKA++EFFC     +++++   +S +     + A N + +++
Sbjct: 519  RNDHPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNAAGDFM 578

Query: 427  SNT------------------------GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWK 320
            S++                        G + V AVTWGVF  KE++ PTI++  SF+ W 
Sbjct: 579  SSSPATDATTEDSSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWG 638

Query: 319  DEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
            DEAF IW   W  ++P   P+ +LL+++KN  +L+  V   Y
Sbjct: 639  DEAFRIWD-EWRRIFPRGSPTERLLDQLKNDVWLICCVGQKY 679

[164][TOP]
>UniRef100_A6QT35 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
            NAm1 RepID=A6QT35_AJECN
          Length = 712

 Score =  105 bits (262), Expect = 3e-21
 Identities = 52/162 (32%), Positives = 87/162 (53%), Gaps = 28/162 (17%)
 Frame = -2

Query: 595  KSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWV 428
            ++D P  GWG  G G+V+QKA++EFFC     +++++   +S +     + A N + +++
Sbjct: 518  RNDHPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNAAGDFM 577

Query: 427  SNT------------------------GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWK 320
            S++                        G + V AVTWGVF  KE++ PTI++  SF+ W 
Sbjct: 578  SSSPATDAATEDFSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWG 637

Query: 319  DEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
            DEAF IW   W  ++P   P+ +LL+++KN  +L+  V   Y
Sbjct: 638  DEAFRIWD-EWRRIFPRGSPTERLLDQLKNDVWLICCVGQKY 678

[165][TOP]
>UniRef100_C6HED8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
            H143 RepID=C6HED8_AJECH
          Length = 713

 Score =  105 bits (261), Expect = 4e-21
 Identities = 52/162 (32%), Positives = 87/162 (53%), Gaps = 28/162 (17%)
 Frame = -2

Query: 595  KSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWV 428
            ++D P  GWG  G G+V+QKA++EFFC     +++++   +S +     + A N + +++
Sbjct: 519  RNDHPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNVAGDFM 578

Query: 427  SNT------------------------GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWK 320
            S++                        G + V AVTWGVF  KE++ PTI++  SF+ W 
Sbjct: 579  SSSPATDATTEDSSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWG 638

Query: 319  DEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
            DEAF IW   W  ++P   P+ +LL+++KN  +L+  V   Y
Sbjct: 639  DEAFRIWD-EWRRIFPRGSPTERLLDQLKNDVWLICCVGQKY 679

[166][TOP]
>UniRef100_C5DPF1 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
           rouxii CBS 732 RepID=C5DPF1_ZYGRC
          Length = 650

 Score =  105 bits (261), Expect = 4e-21
 Identities = 56/142 (39%), Positives = 78/142 (54%), Gaps = 5/142 (3%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKD-----KLDTLVEKSKAFPSITYMAVNKSENWV 428
           S +   GWG   G VYQKA++E F  K+      +   +E+      +TY A +   N+ 
Sbjct: 503 STNKIFGWGPAYGVVYQKAFIEMFVPKNIWENGNMKKAIEQYGR-AKLTYYANDSQGNFE 561

Query: 427 SNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKL 248
           +N   +  N VTWGVF   +VIQ TIV   SFK W DEAF IW   WA L+P +  +  L
Sbjct: 562 TNLESNSSNVVTWGVFSDSQVIQSTIVSEESFKAWSDEAFSIW-LEWAKLFPRNTSTNSL 620

Query: 247 LEEVKNSYYLVSLVDNNYINGD 182
           L ++   Y L+S+V ++YIN D
Sbjct: 621 LRQIHQEYCLISIVHHDYINPD 642

[167][TOP]
>UniRef100_C4R2L4 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
           RepID=C4R2L4_PICPG
          Length = 596

 Score =  105 bits (261), Expect = 4e-21
 Identities = 53/138 (38%), Positives = 83/138 (60%), Gaps = 2/138 (1%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKL-DTLVEKSKAFPSITYMAVNKSENWVSNT 419
           KS     GWG   GYVYQKA++E F +K +  + ++   +   S+T+   + +  + +N 
Sbjct: 449 KSTDKLFGWGPSEGYVYQKAFVEVFINKKQWNEEILPNLQGHKSVTWYLGDCNNAFDTNI 508

Query: 418 G-ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
                 N+VTWG FP KE++Q TI+   SF+ W +EAF IW R W  LYP++  S  LL 
Sbjct: 509 KIPLSSNSVTWGCFPDKEIVQTTIIGEESFQAWNEEAFNIW-REWQKLYPKNTASYNLLG 567

Query: 241 EVKNSYYLVSLVDNNYIN 188
            + N++YLV+L++++Y N
Sbjct: 568 SIINNFYLVTLINHDYAN 585

[168][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
           7966 RepID=A8QAM7_MALGO
          Length = 589

 Score =  105 bits (261), Expect = 4e-21
 Identities = 52/135 (38%), Positives = 83/135 (61%), Gaps = 2/135 (1%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS-ITYMAVN-KSENWVSNT 419
           S  P  G+G  GGY++QKA++E F +++  + LV+  +   + +TY A       + +N 
Sbjct: 442 STDPTFGFGPQGGYIFQKAFVELFMNENDKNALVQMIQGSSTPVTYFAGKCDPTTFETNL 501

Query: 418 GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEE 239
             + +N VTWGVFP  EV Q TI++ ASF+ W+DEAF IW R W  L+P +  +R LL  
Sbjct: 502 TTNGLNTVTWGVFPGTEVAQSTIIEEASFRAWRDEAFAIW-REWELLFPPNSATRSLLRR 560

Query: 238 VKNSYYLVSLVDNNY 194
           + +  +LV++V ++Y
Sbjct: 561 IHDERWLVTVVHHDY 575

[169][TOP]
>UniRef100_A4RH85 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
           RepID=A4RH85_MAGGR
          Length = 662

 Score =  105 bits (261), Expect = 4e-21
 Identities = 55/158 (34%), Positives = 84/158 (53%), Gaps = 23/158 (14%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT-YMAVNKSENWVSNT 419
           +S+    GWG   G+V+QKA++E F        L EK  +   +  + A N   ++ S+ 
Sbjct: 495 RSNDRTFGWGPQNGFVFQKAFVEMFLPSKDWKALREKLLSEKDVVCFYASNAKGDFESSD 554

Query: 418 GESDV----------------------NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFE 305
           G  D                       NAVTWGVFP KE++ PTI++  SF+ W +EAF 
Sbjct: 555 GGGDAPDGAPTGNGFADEQPLPSGSSTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFG 614

Query: 304 IWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNNYI 191
           IW+  WA +Y +D PS KLLE ++   +LV+++ ++YI
Sbjct: 615 IWA-EWAKVYGKDSPSEKLLESLRADLWLVNIIHHDYI 651

[170][TOP]
>UniRef100_A1C4Z1 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
           RepID=A1C4Z1_ASPCL
          Length = 690

 Score =  105 bits (261), Expect = 4e-21
 Identities = 52/150 (34%), Positives = 84/150 (56%), Gaps = 16/150 (10%)
 Frame = -2

Query: 595 KSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVEK---SKAFPSITYMAVNKSENWV 428
           +SD+   GWG PG G+V+QK ++EFFC     +T+++    +     + + A N    + 
Sbjct: 516 RSDNSTFGWGPPGEGFVFQKPFVEFFCPSKDFETVLKPLFANHGHEKLAWFATNAKGEFQ 575

Query: 427 SN----TGESD--------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWA 284
           S+    T +SD        VNAVTWGVF  KE++ PTI++  SF+ W +EA+ IW   W 
Sbjct: 576 SSLPAETADSDALEPNPDNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAYRIW-EEWR 634

Query: 283 NLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
            +YP    + + ++E KN  +LV +V  ++
Sbjct: 635 RIYPRGSATERFIDETKNDVWLVCVVGQDF 664

[171][TOP]
>UniRef100_Q6BM19 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
           RepID=Q6BM19_DEBHA
          Length = 642

 Score =  103 bits (257), Expect = 1e-20
 Identities = 56/142 (39%), Positives = 78/142 (54%), Gaps = 9/142 (6%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKD----KLDTLVEKSKAFPSITYMAVNKSENWVS 425
           S     GWG   G +YQKA++E F  KD    KL   ++K     +ITY   +      S
Sbjct: 488 SSDKIFGWGPGNGIIYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTITYYCGDAEGRLTS 547

Query: 424 NTG-----ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDP 260
           N        +  NA+TWGVFP+KEV+QPTI+D  SFK W +EAF +W   WA  Y +   
Sbjct: 548 NLNIDQEHYNSKNAITWGVFPSKEVLQPTIIDLESFKAWNEEAFILW-LEWARCYKKTSK 606

Query: 259 SRKLLEEVKNSYYLVSLVDNNY 194
           + +LL  +   YYLVSL+ +++
Sbjct: 607 TYELLNSIYKDYYLVSLISHDF 628

[172][TOP]
>UniRef100_C1H0K0 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
           brasiliensis Pb01 RepID=C1H0K0_PARBA
          Length = 713

 Score =  103 bits (257), Expect = 1e-20
 Identities = 56/157 (35%), Positives = 86/157 (54%), Gaps = 23/157 (14%)
 Frame = -2

Query: 595 KSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWV 428
           +SD P  GWG  G G+V+QKA++EFFCS    + +++   K      +++ A N S ++ 
Sbjct: 523 RSDHPIFGWGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQ 582

Query: 427 SN------TGESD-------------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFE 305
           S+      TG  D             VNAVTWGVF  KE+I PTI++  SF+ W DEAF 
Sbjct: 583 SSSSFTGITGLDDAVPDYNGAASSNGVNAVTWGVFKGKEIITPTIIEEVSFRAWGDEAFR 642

Query: 304 IWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
           IW   W  ++    P+ +LL+++K   +L+ +V   +
Sbjct: 643 IWD-EWRRIFRRGSPTEQLLDQLKKDAWLICVVGQKF 678

[173][TOP]
>UniRef100_A3LW82 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
           RepID=A3LW82_PICST
          Length = 635

 Score =  103 bits (256), Expect = 1e-20
 Identities = 57/144 (39%), Positives = 84/144 (58%), Gaps = 10/144 (6%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-----SITYMAVNKSENW 431
           KS     GWG   G VYQKA++E F  K++ ++ + KS   P     +ITY   +   N 
Sbjct: 482 KSTDRIFGWGPKNGIVYQKAFVEIFVPKEQWESEL-KSSLKPHFEEKTITYYVGDAEGNI 540

Query: 430 VSNT-----GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 266
            SN        +  NA+TWGVFP+KEV+QPTI+D  SFK W +EAF +W   WA  Y ++
Sbjct: 541 ESNLFVGPDAHNSKNAITWGVFPSKEVLQPTIIDYESFKAWNEEAFLLWI-EWARCYKKN 599

Query: 265 DPSRKLLEEVKNSYYLVSLVDNNY 194
             + +LL  + ++Y LVSL+ +++
Sbjct: 600 TKTFQLLNSIYSNYVLVSLIHHDF 623

[174][TOP]
>UniRef100_UPI00003BE162 hypothetical protein DEHA0F09867g n=1 Tax=Debaryomyces hansenii
           CBS767 RepID=UPI00003BE162
          Length = 642

 Score =  102 bits (255), Expect = 2e-20
 Identities = 56/142 (39%), Positives = 77/142 (54%), Gaps = 9/142 (6%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKD----KLDTLVEKSKAFPSITYMAVNKSENWVS 425
           S     GWG   G +YQKA++E F  KD    KL   ++K     +ITY   +      S
Sbjct: 488 SSDKIFGWGPGNGIIYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTITYYCGDAEGRLTS 547

Query: 424 NTG-----ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDP 260
           N        +  NA+TWGVFP KEV+QPTI+D  SFK W +EAF +W   WA  Y +   
Sbjct: 548 NLNIDQEHYNSKNAITWGVFPLKEVLQPTIIDLESFKAWNEEAFILW-LEWARCYKKTSK 606

Query: 259 SRKLLEEVKNSYYLVSLVDNNY 194
           + +LL  +   YYLVSL+ +++
Sbjct: 607 TYELLNSIYKDYYLVSLISHDF 628

[175][TOP]
>UniRef100_Q2UA39 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus oryzae
           RepID=Q2UA39_ASPOR
          Length = 690

 Score =  101 bits (251), Expect = 5e-20
 Identities = 56/151 (37%), Positives = 86/151 (56%), Gaps = 17/151 (11%)
 Frame = -2

Query: 595 KSDSPAIGWGGPG-GYVYQKAYLEFFC-SKDK---LDTLVEKSKAFPSITYMAVNKSENW 431
           +SD P  GWG P  G+V+QK ++EFFC SKD    L  L++K      + + A N   ++
Sbjct: 515 RSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLLQKH-GHEKLAWFAANVKGDF 573

Query: 430 VSN----TGESD--------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSW 287
            S+    T ++D        VN VTWGVF  KE++ PTI++  SF+ W DEAF IW   W
Sbjct: 574 ESSLPAQTSDADPIEMNPNNVNCVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD-EW 632

Query: 286 ANLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
             +YP +  + + L ++K+  +LV +V  ++
Sbjct: 633 RRIYPRNSATERFLNDIKDDVWLVCVVGQDF 663

[176][TOP]
>UniRef100_B8NQE8 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus flavus
            NRRL3357 RepID=B8NQE8_ASPFN
          Length = 738

 Score =  101 bits (251), Expect = 5e-20
 Identities = 56/151 (37%), Positives = 86/151 (56%), Gaps = 17/151 (11%)
 Frame = -2

Query: 595  KSDSPAIGWGGPG-GYVYQKAYLEFFC-SKDK---LDTLVEKSKAFPSITYMAVNKSENW 431
            +SD P  GWG P  G+V+QK ++EFFC SKD    L  L++K      + + A N   ++
Sbjct: 563  RSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLLQKH-GHEKLAWFAANVKGDF 621

Query: 430  VSN----TGESD--------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSW 287
             S+    T ++D        VN VTWGVF  KE++ PTI++  SF+ W DEAF IW   W
Sbjct: 622  ESSLPAQTSDADPIEMNPNNVNCVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD-EW 680

Query: 286  ANLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
              +YP +  + + L ++K+  +LV +V  ++
Sbjct: 681  RRIYPRNSATERFLNDIKDDVWLVCVVGQDF 711

[177][TOP]
>UniRef100_C1GJU2 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
           brasiliensis Pb18 RepID=C1GJU2_PARBD
          Length = 712

 Score =  100 bits (250), Expect = 7e-20
 Identities = 55/157 (35%), Positives = 85/157 (54%), Gaps = 23/157 (14%)
 Frame = -2

Query: 595 KSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWV 428
           +SD P  GWG  G G+V+QKA++EFFCS    + +++   K      +++ A N S ++ 
Sbjct: 523 RSDHPIFGWGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQ 582

Query: 427 SN------TGESD-------------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFE 305
           S+      TG  D             VNAVTWGVF  KE+I PTI++  SF+ W  EAF 
Sbjct: 583 SSSSFTGTTGLDDAVPDYNGAASSNGVNAVTWGVFKGKEIITPTIIEEVSFRAWGHEAFR 642

Query: 304 IWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
           IW   W  ++    P+ +LL+++K   +L+ +V   +
Sbjct: 643 IWD-EWRRIFRRGSPTEQLLDQLKKDAWLICVVGQKF 678

[178][TOP]
>UniRef100_C0S8C4 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
           brasiliensis Pb03 RepID=C0S8C4_PARBP
          Length = 712

 Score =  100 bits (250), Expect = 7e-20
 Identities = 55/157 (35%), Positives = 85/157 (54%), Gaps = 23/157 (14%)
 Frame = -2

Query: 595 KSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWV 428
           +SD P  GWG  G G+V+QKA++EFFCS    + +++   K      +++ A N S ++ 
Sbjct: 523 RSDHPIFGWGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQ 582

Query: 427 SN------TGESD-------------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFE 305
           S+      TG  D             VNAVTWGVF  KE+I PTI++  SF+ W  EAF 
Sbjct: 583 SSSSFTGTTGLDDAVPDYSGAASSNGVNAVTWGVFKGKEIITPTIIEEVSFRAWGHEAFR 642

Query: 304 IWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
           IW   W  ++    P+ +LL+++K   +L+ +V   +
Sbjct: 643 IWD-EWRRIFRRGSPTEQLLDQLKKDAWLICVVGQKF 678

[179][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
           RepID=Q59GJ6_HUMAN
          Length = 672

 Score =  100 bits (249), Expect = 9e-20
 Identities = 45/92 (48%), Positives = 60/92 (65%), Gaps = 1/92 (1%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTG 416
           S  P +GWG  GGYV+QKAYLEFF S++  + L++  K +   + Y  VN     ++N  
Sbjct: 523 SSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAP 582

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWK 320
           E   NAVTWG+FP +E+IQPT+VDP SF  WK
Sbjct: 583 ELQPNAVTWGIFPGREIIQPTVVDPVSFMFWK 614

[180][TOP]
>UniRef100_Q2HBA5 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
           RepID=Q2HBA5_CHAGB
          Length = 643

 Score = 99.0 bits (245), Expect = 3e-19
 Identities = 47/138 (34%), Positives = 75/138 (54%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTG 416
           +S  P  GWG   G+V+QKA++EFF        L ++           +N+ E       
Sbjct: 516 RSSDPTFGWGPQNGFVFQKAFVEFFLPLADWAALEKR-----------LNRPEMEGRRER 564

Query: 415 ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
           E+  NAV+WGVFP KE++ PTI++  SF+ W +EAF IW   W  +Y +   S + LE V
Sbjct: 565 EASTNAVSWGVFPGKEIVPPTIIEEVSFRAWSEEAFGIWG-EWVKIYEKGSESERFLERV 623

Query: 235 KNSYYLVSLVDNNYINGD 182
               +LV+++ ++++  D
Sbjct: 624 LADTWLVNIIHHDFLETD 641

[181][TOP]
>UniRef100_A5DZ35 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
           elongisporus RepID=A5DZ35_LODEL
          Length = 622

 Score = 99.0 bits (245), Expect = 3e-19
 Identities = 56/139 (40%), Positives = 79/139 (56%), Gaps = 5/139 (3%)
 Frame = -2

Query: 595 KSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSN-- 422
           +S+    GWG   G VYQK+++E F        L  K +   + TY   +KS     +  
Sbjct: 475 RSNDNVFGWGPGNGVVYQKSFVELFIPAKDWKEL--KPRLDDATTYYVGDKSGRIELSLF 532

Query: 421 TGESD---VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRK 251
           T ES     NAVTWGVFP KEV+QPT++D  SFK W +EAF +W   WA  Y ++  + +
Sbjct: 533 TNESTRHLKNAVTWGVFPLKEVVQPTVIDYESFKAWNEEAFLLW-LEWARCYKKNSKTYE 591

Query: 250 LLEEVKNSYYLVSLVDNNY 194
           LL  V+++Y LVSL+ + Y
Sbjct: 592 LLNSVRDNYVLVSLIHHEY 610

[182][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
           113480 RepID=C5FI42_NANOT
          Length = 715

 Score = 98.2 bits (243), Expect = 4e-19
 Identities = 53/163 (32%), Positives = 81/163 (49%), Gaps = 29/163 (17%)
 Frame = -2

Query: 595 KSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWV 428
           ++D P  GWG  G G+V+QKA++EFFC  D   + ++    S       + A+N   ++ 
Sbjct: 480 RNDHPIFGWGPRGEGFVFQKAFVEFFCPGDDFHSKLKPLLNSYGHDEFAWFAMNAKGDFQ 539

Query: 427 SNTG-------------------------ESDVNAVTWGVFPAKEVIQPTIVDPASFKVW 323
           S+T                             VNAVTWGVF  KE++ PTI++  SF+ W
Sbjct: 540 SSTSPEPPASPPTDSTEPLFDTDPLTDMDNGSVNAVTWGVFRGKEIVTPTIIEAVSFRAW 599

Query: 322 KDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
            +EAF IW   W  ++P    S KL+ +VK+  +LV +V   +
Sbjct: 600 GEEAFGIW-EEWRRIFPRGSASEKLIRDVKDDVWLVCVVGQRF 641

[183][TOP]
>UniRef100_C7GU28 Met12p n=2 Tax=Saccharomyces cerevisiae RepID=C7GU28_YEAS2
          Length = 657

 Score = 97.8 bits (242), Expect = 6e-19
 Identities = 52/140 (37%), Positives = 76/140 (54%), Gaps = 3/140 (2%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF---PSITYMAVNKSENWVSN 422
           S     GWG   G +YQKA++E F  + + +T ++           +Y A + S ++ +N
Sbjct: 509 SSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETN 568

Query: 421 TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
                 + VTWGVFP   V Q TI++  SFK W+DEAF IWS  WA L+P + P+  LL 
Sbjct: 569 LDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPANILLR 627

Query: 241 EVKNSYYLVSLVDNNYINGD 182
            V   Y LVS+V +++   D
Sbjct: 628 LVHKDYCLVSIVHHDFKETD 647

[184][TOP]
>UniRef100_B5VTD9 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
           cerevisiae AWRI1631 RepID=B5VTD9_YEAS6
          Length = 657

 Score = 97.8 bits (242), Expect = 6e-19
 Identities = 52/140 (37%), Positives = 76/140 (54%), Gaps = 3/140 (2%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF---PSITYMAVNKSENWVSN 422
           S     GWG   G +YQKA++E F  + + +T ++           +Y A + S ++ +N
Sbjct: 509 SSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETN 568

Query: 421 TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
                 + VTWGVFP   V Q TI++  SFK W+DEAF IWS  WA L+P + P+  LL 
Sbjct: 569 LDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPANILLR 627

Query: 241 EVKNSYYLVSLVDNNYINGD 182
            V   Y LVS+V +++   D
Sbjct: 628 LVHKDYCLVSIVHHDFKETD 647

[185][TOP]
>UniRef100_B3LL40 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
           cerevisiae RM11-1a RepID=B3LL40_YEAS1
          Length = 657

 Score = 97.8 bits (242), Expect = 6e-19
 Identities = 52/140 (37%), Positives = 76/140 (54%), Gaps = 3/140 (2%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF---PSITYMAVNKSENWVSN 422
           S     GWG   G +YQKA++E F  + + +T ++           +Y A + S ++ +N
Sbjct: 509 SSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETN 568

Query: 421 TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
                 + VTWGVFP   V Q TI++  SFK W+DEAF IWS  WA L+P + P+  LL 
Sbjct: 569 LDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPANILLR 627

Query: 241 EVKNSYYLVSLVDNNYINGD 182
            V   Y LVS+V +++   D
Sbjct: 628 LVHKDYCLVSIVHHDFKETD 647

[186][TOP]
>UniRef100_P46151 Methylenetetrahydrofolate reductase 1 n=1 Tax=Saccharomyces
           cerevisiae RepID=MTHR1_YEAST
          Length = 657

 Score = 97.8 bits (242), Expect = 6e-19
 Identities = 52/140 (37%), Positives = 76/140 (54%), Gaps = 3/140 (2%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF---PSITYMAVNKSENWVSN 422
           S     GWG   G +YQKA++E F  + + +T ++           +Y A + S ++ +N
Sbjct: 509 SSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETN 568

Query: 421 TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
                 + VTWGVFP   V Q TI++  SFK W+DEAF IWS  WA L+P + P+  LL 
Sbjct: 569 LDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPANILLR 627

Query: 241 EVKNSYYLVSLVDNNYINGD 182
            V   Y LVS+V +++   D
Sbjct: 628 LVHKDYCLVSIVHHDFKETD 647

[187][TOP]
>UniRef100_B6HK87 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
           Wisconsin 54-1255 RepID=B6HK87_PENCW
          Length = 691

 Score = 97.4 bits (241), Expect = 7e-19
 Identities = 51/151 (33%), Positives = 78/151 (51%), Gaps = 18/151 (11%)
 Frame = -2

Query: 592 SDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSENWVS 425
           +D P  GWG    G+V+QK ++EFFCS +    +++   A      +T+ A N   ++ S
Sbjct: 515 NDHPIFGWGPQREGFVFQKPFVEFFCSSNDYTNILKPLFAKHGHDKLTWFATNVKGDFES 574

Query: 424 N--------------TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSW 287
           +              +    VNAVTWGVF  KE++ PTI++  SF+ W +EAF IW   W
Sbjct: 575 SLPAQPADMDLDDLGSNPESVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EW 633

Query: 286 ANLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
             +YP   P+   L+  KN  +LV +V   +
Sbjct: 634 RRIYPRGSPTETYLDTTKNDSWLVCVVGQQF 664

[188][TOP]
>UniRef100_C4JM22 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii 1704
            RepID=C4JM22_UNCRE
          Length = 709

 Score = 97.1 bits (240), Expect = 1e-18
 Identities = 53/162 (32%), Positives = 81/162 (50%), Gaps = 28/162 (17%)
 Frame = -2

Query: 595  KSDSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWV 428
            +SD    GWG PG G+V+QKA++EFFCS +   + ++   +        + A N + ++ 
Sbjct: 519  RSDDTTFGWGPPGEGFVFQKAFVEFFCSSNDYRSYLKPLLQRYGHDEFAWFATNAAGDFE 578

Query: 427  SNTGES------------------------DVNAVTWGVFPAKEVIQPTIVDPASFKVWK 320
            ++T  S                         VNAVTWGVF  KE+I PTI++  SF+ W 
Sbjct: 579  ASTPPSAHSPTEPVDAGFEDPSSPAASNPGGVNAVTWGVFRGKEIITPTIIEEVSFRAWG 638

Query: 319  DEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
            +EAF IW   W  ++    P+ KLL + K   +LV +V   +
Sbjct: 639  EEAFRIWD-EWRRIFARGSPTEKLLAQTKEDVWLVCVVGQRF 679

[189][TOP]
>UniRef100_B8MDD4 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
            ATCC 10500 RepID=B8MDD4_TALSN
          Length = 713

 Score = 97.1 bits (240), Expect = 1e-18
 Identities = 57/170 (33%), Positives = 81/170 (47%), Gaps = 31/170 (18%)
 Frame = -2

Query: 595  KSDSPAIGWGGPG-GYVYQKAYLEFFC------SKDKLDTLVEKSKAF------------ 473
            +SD P  GWG PG G+V+QKA++EFFC      +K K   L   S+ F            
Sbjct: 524  RSDHPVFGWGPPGEGFVFQKAFVEFFCPSSDYQNKVKPTLLKHGSEEFSWFAINAAGHLE 583

Query: 472  ------------PSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFK 329
                        P  T  AV  ++       ES   AVTWG F  +E+  PTI++  SF+
Sbjct: 584  SSFLISTSSSPKPEDTSSAVAAADEEPLEIRESTGMAVTWGAFRGREITTPTIIEEVSFR 643

Query: 328  VWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNNYINGDI 179
             W +EAF IW   W  +YP    + +LL E KN  +L+ ++ + Y  G +
Sbjct: 644  AWGEEAFRIWD-EWRRIYPRGSATERLLNETKNDVWLLCVIGHRYGAGTV 692

[190][TOP]
>UniRef100_C9S8T9 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
           VaMs.102 RepID=C9S8T9_9PEZI
          Length = 670

 Score = 96.7 bits (239), Expect = 1e-18
 Identities = 48/146 (32%), Positives = 80/146 (54%), Gaps = 12/146 (8%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEK---SKAFPSITYMAVNKSENWVSN 422
           S     GWG   G+V+QKA++E F        L E+    +   ++ + A N + ++ ++
Sbjct: 515 SRDATFGWGPSHGFVFQKAFVELFLPAADWKVLSERLTGPEVEGTVCFYACNGNGDFATS 574

Query: 421 TGE---------SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPE 269
                       +  NAVTWGVFP KE+I PTI++  SF+ W +EAF+IW   W+ +Y  
Sbjct: 575 DDSGGLVRTAVPASTNAVTWGVFPGKEIITPTIIEEVSFRAWSEEAFKIWG-EWSRVYGR 633

Query: 268 DDPSRKLLEEVKNSYYLVSLVDNNYI 191
              S K L+ VK  Y+LV+++ ++++
Sbjct: 634 GHESEKFLKTVKEEYWLVNIIHHDFV 659

[191][TOP]
>UniRef100_B6QFH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
            ATCC 18224 RepID=B6QFH8_PENMQ
          Length = 710

 Score = 93.6 bits (231), Expect = 1e-17
 Identities = 55/167 (32%), Positives = 82/167 (49%), Gaps = 33/167 (19%)
 Frame = -2

Query: 595  KSDSPAIGWGGPG-GYVYQKAYLEFFC------SKDKLDTLVEKSKAFPSITYMAVNKSE 437
            +SD P  GWG PG G+V+QKA++EFFC      +K K   L   S+ F   ++ A+N + 
Sbjct: 522  RSDHPVFGWGPPGEGFVFQKAFVEFFCPNADYQNKVKPTLLKHGSEEF---SWFAINATG 578

Query: 436  NWVSN--------------------------TGESDVNAVTWGVFPAKEVIQPTIVDPAS 335
            +  S+                            ES   AVTWG F  +E+  PTI++  S
Sbjct: 579  HLESSFLLSASSSPKPEDASSTIAADEEPVEVRESKGMAVTWGAFRGREITTPTIIEEVS 638

Query: 334  FKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNNY 194
            F+ W +EAF IW   W  +YP    + +LL E KN  +L+ ++ + Y
Sbjct: 639  FRAWGEEAFRIWD-EWRRIYPRGSATERLLNETKNDAWLLCVIGHRY 684

[192][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
           (Silurana) tropicalis RepID=UPI00006A0177
          Length = 641

 Score = 89.7 bits (221), Expect = 2e-16
 Identities = 55/143 (38%), Positives = 78/143 (54%), Gaps = 10/143 (6%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSENWV---- 428
           S  P +GWG   GYV+QKAYLEFF S + +  L++  K + P + Y  VN  ++      
Sbjct: 487 STDPIVGWGPSRGYVFQKAYLEFFTSSEMVTALIKVLKRYEPRVNYHIVNVHKHTQLLKL 546

Query: 427 ---SNTGESDV--NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDD 263
              S+TG   V  NA   G      VI  +I D        DEAF +W   WA LY E+ 
Sbjct: 547 LSSSDTGMGPVIQNAQDLGNL---SVIWISITD--------DEAFALWIEQWAKLYEEES 595

Query: 262 PSRKLLEEVKNSYYLVSLVDNNY 194
           PSR +++ + ++YYLV+LVDN++
Sbjct: 596 PSRMIIQYIHDNYYLVNLVDNDF 618

[193][TOP]
>UniRef100_A7S359 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
           RepID=A7S359_NEMVE
          Length = 102

 Score = 62.0 bits (149), Expect = 3e-08
 Identities = 28/60 (46%), Positives = 39/60 (65%)
 Frame = -2

Query: 592 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 413
           S  P +GWGG GGY+YQKAYLEFF S + +  L+++ K +P + Y  VN   N + N G+
Sbjct: 44  STDPLLGWGGEGGYIYQKAYLEFFASPEVVYILLQELKNYPQVNYHVVN---NHLRNLGK 100