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[1][TOP]
>UniRef100_B9DI07 AT1G74040 protein (Fragment) n=1 Tax=Arabidopsis thaliana
RepID=B9DI07_ARATH
Length = 491
Score = 279 bits (713), Expect = 8e-74
Identities = 141/141 (100%), Positives = 141/141 (100%)
Frame = +2
Query: 2 NELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGT 181
NELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGT
Sbjct: 298 NELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGT 357
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI
Sbjct: 358 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 417
Query: 362 ATTRVLIRGDNNYSSTNAVTG 424
ATTRVLIRGDNNYSSTNAVTG
Sbjct: 418 ATTRVLIRGDNNYSSTNAVTG 438
[2][TOP]
>UniRef100_Q9C550 2-isopropylmalate synthase 2, chloroplastic n=1 Tax=Arabidopsis
thaliana RepID=LEU12_ARATH
Length = 631
Score = 279 bits (713), Expect = 8e-74
Identities = 141/141 (100%), Positives = 141/141 (100%)
Frame = +2
Query: 2 NELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGT 181
NELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGT
Sbjct: 438 NELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGT 497
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI
Sbjct: 498 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 557
Query: 362 ATTRVLIRGDNNYSSTNAVTG 424
ATTRVLIRGDNNYSSTNAVTG
Sbjct: 558 ATTRVLIRGDNNYSSTNAVTG 578
[3][TOP]
>UniRef100_Q5FAL5 Putative 2-isopropylmalate synthase n=1 Tax=Brassica oleracea
RepID=Q5FAL5_BRAOL
Length = 623
Score = 256 bits (655), Expect = 4e-67
Identities = 125/140 (89%), Positives = 139/140 (99%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGYVLDD QLS++FWRFK+VAE+KKRVTDAD+IALVSDEVFQPEA+WKLLD+QITCGTL
Sbjct: 433 ELGYVLDDEQLSSIFWRFKSVAERKKRVTDADIIALVSDEVFQPEALWKLLDIQITCGTL 492
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
GLST+TVKLAD+DGKEHVACS+GTGPVD+AYKAVDLIVKEPATLLEYSMNAVTEGIDAIA
Sbjct: 493 GLSTATVKLADADGKEHVACSMGTGPVDSAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 552
Query: 365 TTRVLIRGDNNYSSTNAVTG 424
TTRVLIRG+NNYS+TNA+TG
Sbjct: 553 TTRVLIRGNNNYSTTNAITG 572
[4][TOP]
>UniRef100_Q30DX9 2-isopropylmalate synthase 1 n=1 Tax=Brassica insularis
RepID=Q30DX9_9BRAS
Length = 623
Score = 256 bits (655), Expect = 4e-67
Identities = 125/140 (89%), Positives = 139/140 (99%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGYVLDD QLS++FWRFK+VAE+KKRVTDAD+IALVSDEVFQPEA+WKLLD+QITCGTL
Sbjct: 433 ELGYVLDDEQLSSIFWRFKSVAERKKRVTDADIIALVSDEVFQPEALWKLLDIQITCGTL 492
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
GLST+TVKLAD+DGKEHVACS+GTGPVD+AYKAVDLIVKEPATLLEYSMNAVTEGIDAIA
Sbjct: 493 GLSTATVKLADADGKEHVACSMGTGPVDSAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 552
Query: 365 TTRVLIRGDNNYSSTNAVTG 424
TTRVLIRG+NNYS+TNA+TG
Sbjct: 553 TTRVLIRGNNNYSTTNAITG 572
[5][TOP]
>UniRef100_UPI000034F3A5 MAML-4 (METHYLTHIOALKYLMALATE SYNTHASE-LIKE 4); 2-isopropylmalate
synthase n=1 Tax=Arabidopsis thaliana
RepID=UPI000034F3A5
Length = 631
Score = 255 bits (652), Expect = 9e-67
Identities = 126/140 (90%), Positives = 134/140 (95%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY LDD QLS +FWRFK VAEQKKRVTDAD+IALVSDEVFQPEAVWKLLD+QITCGTL
Sbjct: 441 ELGYQLDDEQLSTIFWRFKTVAEQKKRVTDADIIALVSDEVFQPEAVWKLLDIQITCGTL 500
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
GLST+TVKLAD+DGKEHVACS+GTGPVD+AYKAVDLIVKEPATLLEYSMNAVTEGIDAIA
Sbjct: 501 GLSTATVKLADADGKEHVACSIGTGPVDSAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 560
Query: 365 TTRVLIRGDNNYSSTNAVTG 424
TTRVLIRG N YSSTNA+TG
Sbjct: 561 TTRVLIRGSNKYSSTNAITG 580
[6][TOP]
>UniRef100_B2D157 2-isopropylmalate synthase n=1 Tax=Brassica oleracea
RepID=B2D157_BRAOL
Length = 672
Score = 253 bits (646), Expect = 5e-66
Identities = 123/140 (87%), Positives = 136/140 (97%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGYVLDD QLS +FWRFK+VAEQKKRVTDAD+IALVSDEVFQPEAVWK+LD+QITCGTL
Sbjct: 482 ELGYVLDDEQLSTIFWRFKSVAEQKKRVTDADIIALVSDEVFQPEAVWKVLDIQITCGTL 541
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
GLST+TVKLAD+DGKEH ACS+GTGPVD+AYKAVDLIVKEPATLLEYSMNAVTEGIDAIA
Sbjct: 542 GLSTATVKLADADGKEHCACSMGTGPVDSAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 601
Query: 365 TTRVLIRGDNNYSSTNAVTG 424
TTRVL+RG+N Y+STNA+TG
Sbjct: 602 TTRVLVRGNNTYTSTNAITG 621
[7][TOP]
>UniRef100_Q9LPR4 2-isopropylmalate synthase 1, chloroplastic n=1 Tax=Arabidopsis
thaliana RepID=LEU11_ARATH
Length = 675
Score = 244 bits (623), Expect = 2e-63
Identities = 125/155 (80%), Positives = 134/155 (86%), Gaps = 15/155 (9%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LGY LDD QLS +FWRFK VAEQKKRVTDAD+IALVSDEVFQPEAVWKLLD+QITCGTL
Sbjct: 470 QLGYQLDDEQLSTIFWRFKTVAEQKKRVTDADIIALVSDEVFQPEAVWKLLDIQITCGTL 529
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVK---------------EPATLL 319
GLST+TVKLAD+DGKEHVACS+GTGPVD+AYKAVDLIVK EPATLL
Sbjct: 530 GLSTATVKLADADGKEHVACSIGTGPVDSAYKAVDLIVKVLFIPLRLSSTNNSPEPATLL 589
Query: 320 EYSMNAVTEGIDAIATTRVLIRGDNNYSSTNAVTG 424
EYSMNAVTEGIDAIATTRVLIRG N YSSTNA+TG
Sbjct: 590 EYSMNAVTEGIDAIATTRVLIRGSNKYSSTNAITG 624
[8][TOP]
>UniRef100_B9H597 Predicted protein (Fragment) n=1 Tax=Populus trichocarpa
RepID=B9H597_POPTR
Length = 558
Score = 230 bits (587), Expect = 3e-59
Identities = 113/140 (80%), Positives = 128/140 (91%)
Frame = +2
Query: 2 NELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGT 181
NELGY LDD QL N+FWRFKAVAE KKRVTDADLIALVSDEVFQPE VWKL D+Q+TCGT
Sbjct: 366 NELGYELDDAQLGNIFWRFKAVAETKKRVTDADLIALVSDEVFQPENVWKLHDLQVTCGT 425
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
LGLST+TVKL +DG+EHVACS+GTGPVD+AYKAV+LIVKEP TLLEYSM AVTEGIDAI
Sbjct: 426 LGLSTATVKLLSADGEEHVACSLGTGPVDSAYKAVNLIVKEPVTLLEYSMIAVTEGIDAI 485
Query: 362 ATTRVLIRGDNNYSSTNAVT 421
ATTRV+IRG+N ++ T+A+T
Sbjct: 486 ATTRVVIRGENQHAPTHALT 505
[9][TOP]
>UniRef100_B9SX30 Isopropylmalate synthase, putative n=1 Tax=Ricinus communis
RepID=B9SX30_RICCO
Length = 632
Score = 228 bits (581), Expect = 2e-58
Identities = 112/140 (80%), Positives = 128/140 (91%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L+D QL +FWRFKAVAE KKRVTDADLIALVSDEVFQPE VWKL D+Q+TCGTL
Sbjct: 440 ELGYELNDEQLGTIFWRFKAVAETKKRVTDADLIALVSDEVFQPEIVWKLGDLQVTCGTL 499
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
GLST+TVKL ++DG+EH+ACSVG+GPVDA YKAVDLIVKEP LLEYSMNAVTEGIDAIA
Sbjct: 500 GLSTATVKLINADGEEHIACSVGSGPVDAGYKAVDLIVKEPVELLEYSMNAVTEGIDAIA 559
Query: 365 TTRVLIRGDNNYSSTNAVTG 424
TTRVLIR ++N++ST+A+TG
Sbjct: 560 TTRVLIRREDNHTSTHALTG 579
[10][TOP]
>UniRef100_B7FLQ1 Putative uncharacterized protein n=1 Tax=Medicago truncatula
RepID=B7FLQ1_MEDTR
Length = 416
Score = 222 bits (566), Expect = 9e-57
Identities = 110/140 (78%), Positives = 124/140 (88%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L D Q+ +LFWRFKAVAEQKKR+TDADL ALVSDEVFQ E +WKL D+Q+TCGTL
Sbjct: 242 ELGYELKDDQVESLFWRFKAVAEQKKRITDADLRALVSDEVFQAEPIWKLDDLQVTCGTL 301
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
GLST+TVKL DG H+ACSVGTGPVD+AYKAVDLIVKEPATLLEYSM AVTEGIDAIA
Sbjct: 302 GLSTATVKLVGDDGSAHIACSVGTGPVDSAYKAVDLIVKEPATLLEYSMIAVTEGIDAIA 361
Query: 365 TTRVLIRGDNNYSSTNAVTG 424
TTRV+IRGD + +ST+A+TG
Sbjct: 362 TTRVVIRGDTDQTSTHALTG 381
[11][TOP]
>UniRef100_B5LAV3 Putative isopropylmalate synthase n=1 Tax=Capsicum annuum
RepID=B5LAV3_CAPAN
Length = 602
Score = 218 bits (555), Expect = 2e-55
Identities = 103/140 (73%), Positives = 129/140 (92%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY ++ +L +LFWRFK+VAE+KK++TD DLIAL+SDEVFQP+ VW+L ++Q+TCG+L
Sbjct: 413 ELGYEIEGKELDDLFWRFKSVAEKKKKITDDDLIALMSDEVFQPQFVWQLQNVQVTCGSL 472
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
GLST+TVKL D+DGKEH++CSVGTGPVDAAYKAVDLIVK P TLLEYSMNAVT+GIDAIA
Sbjct: 473 GLSTATVKLIDADGKEHISCSVGTGPVDAAYKAVDLIVKIPVTLLEYSMNAVTQGIDAIA 532
Query: 365 TTRVLIRGDNNYSSTNAVTG 424
+TRVLIRG+N ++ST+A+TG
Sbjct: 533 STRVLIRGENGHTSTHALTG 552
[12][TOP]
>UniRef100_O04974 2-isopropylmalate synthase B n=1 Tax=Solanum pennellii
RepID=LEU1B_SOLPN
Length = 612
Score = 217 bits (552), Expect = 4e-55
Identities = 101/140 (72%), Positives = 129/140 (92%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY ++ +L +LFWRFK+VAE+KK++TD DL+AL+SDEVFQP+ VW+L ++Q+TCG+L
Sbjct: 423 ELGYEIEGKELDDLFWRFKSVAEKKKKITDDDLVALMSDEVFQPQFVWQLQNVQVTCGSL 482
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
GLST+TVKL D+DG+EH++CSVGTGPVDAAYKAVDLIVK P TLLEYSMNAVT+GIDAIA
Sbjct: 483 GLSTATVKLIDADGREHISCSVGTGPVDAAYKAVDLIVKVPVTLLEYSMNAVTQGIDAIA 542
Query: 365 TTRVLIRGDNNYSSTNAVTG 424
+TRVLIRG+N ++ST+A+TG
Sbjct: 543 STRVLIRGENGHTSTHALTG 562
[13][TOP]
>UniRef100_UPI0001983443 PREDICTED: similar to putative isopropylmalate synthase n=1
Tax=Vitis vinifera RepID=UPI0001983443
Length = 615
Score = 214 bits (544), Expect = 3e-54
Identities = 100/140 (71%), Positives = 124/140 (88%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY ++ +L ++FWRFK VAE+KK +TD D+IALVSDE+FQP+ WKL D+Q+TCGTL
Sbjct: 425 ELGYEIEGMELDDIFWRFKEVAEKKKNLTDVDVIALVSDEIFQPKVFWKLGDLQVTCGTL 484
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
GLST+TVKL D+DG++HVACSVGTGPVD+AYKA+DL+VKE TLLEY +NAVTEGIDAIA
Sbjct: 485 GLSTATVKLIDADGQKHVACSVGTGPVDSAYKAIDLLVKEQVTLLEYGLNAVTEGIDAIA 544
Query: 365 TTRVLIRGDNNYSSTNAVTG 424
TTRVLIRG+ N++ TNA+TG
Sbjct: 545 TTRVLIRGEKNHTLTNALTG 564
[14][TOP]
>UniRef100_A7QS57 Chromosome chr5 scaffold_156, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7QS57_VITVI
Length = 447
Score = 214 bits (544), Expect = 3e-54
Identities = 100/140 (71%), Positives = 124/140 (88%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY ++ +L ++FWRFK VAE+KK +TD D+IALVSDE+FQP+ WKL D+Q+TCGTL
Sbjct: 257 ELGYEIEGMELDDIFWRFKEVAEKKKNLTDVDVIALVSDEIFQPKVFWKLGDLQVTCGTL 316
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
GLST+TVKL D+DG++HVACSVGTGPVD+AYKA+DL+VKE TLLEY +NAVTEGIDAIA
Sbjct: 317 GLSTATVKLIDADGQKHVACSVGTGPVDSAYKAIDLLVKEQVTLLEYGLNAVTEGIDAIA 376
Query: 365 TTRVLIRGDNNYSSTNAVTG 424
TTRVLIRG+ N++ TNA+TG
Sbjct: 377 TTRVLIRGEKNHTLTNALTG 396
[15][TOP]
>UniRef100_O04973 2-isopropylmalate synthase A n=1 Tax=Solanum pennellii
RepID=LEU1A_SOLPN
Length = 589
Score = 197 bits (502), Expect = 2e-49
Identities = 98/140 (70%), Positives = 117/140 (83%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY +D +L +LFWRFK+VAE+KK++TD DLIAL+SDEV QP WKL D+QI CG+L
Sbjct: 400 ELGYDIDGKELEDLFWRFKSVAEKKKKITDDDLIALMSDEVLQPNVYWKLGDVQIMCGSL 459
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
GLST+TVKL ++DG+EH+ACSVGTGPVDAAYKAVDLIVK P TLLEYSMNAVTEGIDAIA
Sbjct: 460 GLSTATVKLINTDGQEHIACSVGTGPVDAAYKAVDLIVKVPITLLEYSMNAVTEGIDAIA 519
Query: 365 TTRVLIRGDNNYSSTNAVTG 424
+TRV I + ++ N TG
Sbjct: 520 STRVSICSIDRHTIMNGSTG 539
[16][TOP]
>UniRef100_C4J3S6 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=C4J3S6_MAIZE
Length = 640
Score = 181 bits (460), Expect = 2e-44
Identities = 87/140 (62%), Positives = 110/140 (78%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY + D + + F R+K VAE+KKRVTD D+ AL+SDE+FQP+ +W L D+Q TCGTL
Sbjct: 447 ELGYEISDKEFEDFFKRYKEVAEKKKRVTDEDIEALLSDEIFQPKVIWSLADVQATCGTL 506
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
GLST+TVKL DG+E +ACSVGTGPVDAAYKA+D I++ P L EY M +VTEGIDAIA
Sbjct: 507 GLSTATVKLIAPDGEERIACSVGTGPVDAAYKAIDQIIQIPTVLREYGMTSVTEGIDAIA 566
Query: 365 TTRVLIRGDNNYSSTNAVTG 424
TTRV++ GD +S +A+TG
Sbjct: 567 TTRVVVTGDVTNNSKHALTG 586
[17][TOP]
>UniRef100_B6SWN1 2-isopropylmalate synthase B n=1 Tax=Zea mays RepID=B6SWN1_MAIZE
Length = 642
Score = 181 bits (460), Expect = 2e-44
Identities = 88/140 (62%), Positives = 110/140 (78%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY + D + + F R+K VAE+KKRVTD D+ AL+SDE+FQP+ +W L D+Q TCGTL
Sbjct: 448 ELGYEISDKEFEDFFKRYKEVAEKKKRVTDEDIEALLSDEIFQPKVIWSLADVQATCGTL 507
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
GLST+TVKL DG+E +ACSVGTGPVDAAYKAVD I++ P L EY M +VTEGIDAIA
Sbjct: 508 GLSTATVKLIGPDGEERIACSVGTGPVDAAYKAVDQIIQIPTVLREYGMTSVTEGIDAIA 567
Query: 365 TTRVLIRGDNNYSSTNAVTG 424
TTRV++ GD +S +A+TG
Sbjct: 568 TTRVVVTGDVANNSKHALTG 587
[18][TOP]
>UniRef100_B6SWM0 2-isopropylmalate synthase B n=1 Tax=Zea mays RepID=B6SWM0_MAIZE
Length = 640
Score = 181 bits (460), Expect = 2e-44
Identities = 87/140 (62%), Positives = 110/140 (78%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY + D + + F R+K VAE+KKRVTD D+ AL+SDE+FQP+ +W L D+Q TCGTL
Sbjct: 447 ELGYEISDKEFEDFFKRYKEVAEKKKRVTDEDIEALLSDEIFQPKVIWSLADVQATCGTL 506
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
GLST+TVKL DG+E +ACSVGTGPVDAAYKA+D I++ P L EY M +VTEGIDAIA
Sbjct: 507 GLSTATVKLIAPDGEERIACSVGTGPVDAAYKAIDQIIQIPTVLREYGMTSVTEGIDAIA 566
Query: 365 TTRVLIRGDNNYSSTNAVTG 424
TTRV++ GD +S +A+TG
Sbjct: 567 TTRVVVTGDVTNNSKHALTG 586
[19][TOP]
>UniRef100_C5YQI8 Putative uncharacterized protein Sb08g001160 n=1 Tax=Sorghum
bicolor RepID=C5YQI8_SORBI
Length = 633
Score = 181 bits (459), Expect = 2e-44
Identities = 88/140 (62%), Positives = 111/140 (79%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY + D + + F R+K VAE+KKRVTD DL AL+SDE+FQP+ +W L D+Q TCGTL
Sbjct: 440 ELGYEIGDKEFEDFFKRYKEVAEKKKRVTDEDLEALLSDEIFQPKLIWSLADVQATCGTL 499
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
LST+TVKL DG+E +ACSVGTGPVDAAYKAVD I++ P L EYSM +VTEGIDAIA
Sbjct: 500 SLSTATVKLIGPDGEERIACSVGTGPVDAAYKAVDQIIQIPTVLREYSMTSVTEGIDAIA 559
Query: 365 TTRVLIRGDNNYSSTNAVTG 424
TTRV++ GD + ++ +A+TG
Sbjct: 560 TTRVVVTGDVSINAKHALTG 579
[20][TOP]
>UniRef100_C0P8I4 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=C0P8I4_MAIZE
Length = 626
Score = 181 bits (458), Expect = 3e-44
Identities = 88/140 (62%), Positives = 111/140 (79%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY + D + + F R+K VAE+KKRVTD DL AL+SDE+FQP+ +W L D+Q TCGTL
Sbjct: 433 ELGYEIGDKEFEDFFKRYKEVAEKKKRVTDEDLEALLSDEIFQPKVIWSLADVQATCGTL 492
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
LST+TVKL DG+E +ACSVGTGPVDAAYKAVD I++ P L EYSM +VTEGIDAIA
Sbjct: 493 ALSTATVKLVAPDGEEKIACSVGTGPVDAAYKAVDKIIQIPTVLREYSMTSVTEGIDAIA 552
Query: 365 TTRVLIRGDNNYSSTNAVTG 424
TTRV++ GD + ++ +A+TG
Sbjct: 553 TTRVVVTGDVSNNAKHALTG 572
[21][TOP]
>UniRef100_B6SH97 2-isopropylmalate synthase B n=1 Tax=Zea mays RepID=B6SH97_MAIZE
Length = 624
Score = 180 bits (457), Expect = 4e-44
Identities = 88/140 (62%), Positives = 111/140 (79%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY + D + + F R+K VAE+KKRVTD DL AL+SDE+FQP+ +W L D+Q TCGTL
Sbjct: 431 ELGYEIGDKEFEDFFKRYKEVAEKKKRVTDEDLEALLSDEIFQPKVIWSLADVQATCGTL 490
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
LST+TVKL DG+E +ACSVGTGPVDAAYKAVD I++ P L EYSM +VTEGIDAIA
Sbjct: 491 ALSTATVKLIAPDGEEKIACSVGTGPVDAAYKAVDKIIQIPTVLREYSMTSVTEGIDAIA 550
Query: 365 TTRVLIRGDNNYSSTNAVTG 424
TTRV++ GD + ++ +A+TG
Sbjct: 551 TTRVVVTGDVSNNAKHALTG 570
[22][TOP]
>UniRef100_C5Y4G6 Putative uncharacterized protein Sb05g002540 n=1 Tax=Sorghum
bicolor RepID=C5Y4G6_SORBI
Length = 620
Score = 180 bits (456), Expect = 5e-44
Identities = 87/140 (62%), Positives = 109/140 (77%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY + D + + F R+K VAE+KKRVTD D+ AL+SDE+FQP+ +W L D+Q TCGTL
Sbjct: 427 ELGYEISDKEFEDFFKRYKEVAEKKKRVTDEDIEALLSDEIFQPKVIWSLADVQATCGTL 486
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
GLST+TVKL DG+E + CSVGTGPVDAAYKAVD I++ P L EY M +VTEGIDAIA
Sbjct: 487 GLSTATVKLIAPDGEEKIGCSVGTGPVDAAYKAVDQIIQIPTVLREYGMTSVTEGIDAIA 546
Query: 365 TTRVLIRGDNNYSSTNAVTG 424
TTRV++ GD +S +A+TG
Sbjct: 547 TTRVVVTGDVTNNSKHALTG 566
[23][TOP]
>UniRef100_B8A2E9 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=B8A2E9_MAIZE
Length = 641
Score = 179 bits (455), Expect = 6e-44
Identities = 87/140 (62%), Positives = 110/140 (78%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY + D + + F R+K VAE+KKRVTD D+ AL+SDE+FQP+ +W L D+Q TCGTL
Sbjct: 447 ELGYEISDKEFEDFFKRYKEVAEKKKRVTDEDIEALLSDEIFQPKVIWSLADVQATCGTL 506
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
GLST+TVKL DG+E +ACSVGTGPVDAA+KAVD I++ P L EY M +VTEGIDAIA
Sbjct: 507 GLSTATVKLIGPDGEERIACSVGTGPVDAAHKAVDQIIQIPTVLREYGMTSVTEGIDAIA 566
Query: 365 TTRVLIRGDNNYSSTNAVTG 424
TTRV++ GD +S +A+TG
Sbjct: 567 TTRVVVTGDVANNSKHALTG 586
[24][TOP]
>UniRef100_Q2RAP8 2-isopropylmalate synthase B, putative, expressed n=1 Tax=Oryza
sativa Japonica Group RepID=Q2RAP8_ORYSJ
Length = 635
Score = 176 bits (445), Expect = 9e-43
Identities = 88/140 (62%), Positives = 110/140 (78%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY + D + + F R+K VAE+KKRVTD D+ AL+SDE+FQP+ W L D+Q TCGTL
Sbjct: 443 ELGYEITDKEFEDFFKRYKEVAEKKKRVTDEDIEALLSDEIFQPKVFWSLADVQATCGTL 502
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
GLST+TVKL DG+E +AC+VGTGPVDAAYKAVD I++ P L EYSM +VTEGIDAIA
Sbjct: 503 GLSTATVKLIGPDGEEKIACAVGTGPVDAAYKAVDDIIQIPTVLREYSMTSVTEGIDAIA 562
Query: 365 TTRVLIRGDNNYSSTNAVTG 424
TTRV++ GD + S +A+TG
Sbjct: 563 TTRVVVTGDVS-DSKHALTG 581
[25][TOP]
>UniRef100_B8BJ19 Putative uncharacterized protein n=1 Tax=Oryza sativa Indica Group
RepID=B8BJ19_ORYSI
Length = 609
Score = 176 bits (445), Expect = 9e-43
Identities = 88/140 (62%), Positives = 110/140 (78%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY + D + + F R+K VAE+KKRVTD D+ AL+SDE+FQP+ W L D+Q TCGTL
Sbjct: 417 ELGYEITDKEFEDFFKRYKEVAEKKKRVTDEDIEALLSDEIFQPKVFWSLADVQATCGTL 476
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
GLST+TVKL DG+E +AC+VGTGPVDAAYKAVD I++ P L EYSM +VTEGIDAIA
Sbjct: 477 GLSTATVKLIGPDGEEKIACAVGTGPVDAAYKAVDDIIQIPTVLREYSMTSVTEGIDAIA 536
Query: 365 TTRVLIRGDNNYSSTNAVTG 424
TTRV++ GD + S +A+TG
Sbjct: 537 TTRVVVTGDVS-DSKHALTG 555
[26][TOP]
>UniRef100_Q2QXY9 Os12g0138900 protein n=2 Tax=Oryza sativa RepID=Q2QXY9_ORYSJ
Length = 635
Score = 175 bits (443), Expect = 2e-42
Identities = 88/140 (62%), Positives = 109/140 (77%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY + D + + F R+K VAE+KKRVTD D+ AL+SDE+FQP+ W L D+Q TCGTL
Sbjct: 443 ELGYEITDKEFEDFFKRYKEVAEKKKRVTDEDIEALLSDEIFQPKVFWSLADVQATCGTL 502
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
GLST+TVKL DG E +AC+VGTGPVDAAYKAVD I++ P L EYSM +VTEGIDAIA
Sbjct: 503 GLSTATVKLIGPDGDEKIACAVGTGPVDAAYKAVDDIIQIPTVLREYSMTSVTEGIDAIA 562
Query: 365 TTRVLIRGDNNYSSTNAVTG 424
TTRV++ GD + S +A+TG
Sbjct: 563 TTRVVVTGDVS-DSKHALTG 581
[27][TOP]
>UniRef100_A9T9B8 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9T9B8_PHYPA
Length = 583
Score = 174 bits (442), Expect = 2e-42
Identities = 91/141 (64%), Positives = 107/141 (75%)
Frame = +2
Query: 2 NELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGT 181
N+LGY +D L ++F RFKAVAE+KK V+D DL L+SDEVFQPE +W + +Q+ CGT
Sbjct: 387 NQLGYEIDGQDLDDVFKRFKAVAEKKKNVSDDDLEILLSDEVFQPETLWSVGLIQVVCGT 446
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
GLST+TVKL DG EH+ SVGTGPVDAAYKAVD IVK P TLLEYSM+AVTEGIDAI
Sbjct: 447 SGLSTATVKLVGPDGVEHIGMSVGTGPVDAAYKAVDTIVKAPVTLLEYSMHAVTEGIDAI 506
Query: 362 ATTRVLIRGDNNYSSTNAVTG 424
A TRV IR + + TN TG
Sbjct: 507 AHTRVQIRALDPLTVTNPQTG 527
[28][TOP]
>UniRef100_UPI0000DD9B13 Os11g0142500 n=1 Tax=Oryza sativa Japonica Group
RepID=UPI0000DD9B13
Length = 639
Score = 174 bits (440), Expect = 4e-42
Identities = 87/139 (62%), Positives = 109/139 (78%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY + D + + F R+K VAE+KKRVTD D+ AL+SDE+FQP+ W L D+Q TCGTLG
Sbjct: 448 LGYEITDKEFEDFFKRYKEVAEKKKRVTDEDIEALLSDEIFQPKVFWSLADVQATCGTLG 507
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
LST+TVKL DG+E +AC+VGTGPVDAAYKAVD I++ P L EYSM +VTEGIDAIAT
Sbjct: 508 LSTATVKLIGPDGEEKIACAVGTGPVDAAYKAVDDIIQIPTVLREYSMTSVTEGIDAIAT 567
Query: 368 TRVLIRGDNNYSSTNAVTG 424
TRV++ GD + S +A+TG
Sbjct: 568 TRVVVTGDVS-DSKHALTG 585
[29][TOP]
>UniRef100_Q39891 Probable 2-isopropylmalate synthase n=1 Tax=Glycine max
RepID=LEU1_SOYBN
Length = 565
Score = 171 bits (433), Expect = 2e-41
Identities = 82/139 (58%), Positives = 109/139 (78%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L + ++ ++FW+FKA+AE+KK VTD DL ALVS + F E++WKL D+Q+TCGT+
Sbjct: 385 ELGYDLKEDEVDSVFWQFKAMAEKKKVVTDVDLKALVSYKAFHAESIWKLGDLQVTCGTI 444
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
GLST+TVKL + DG HVACS+G G VD+ YKA++LIVKEP LL+YS+N+VTEGI
Sbjct: 445 GLSTATVKLVNIDGSTHVACSIGIGAVDSTYKAINLIVKEPTKLLDYSLNSVTEGIGVNV 504
Query: 365 TTRVLIRGDNNYSSTNAVT 421
T RV+I +NN++ST A T
Sbjct: 505 TARVVICRENNHTSTYAFT 523
[30][TOP]
>UniRef100_A9S4K9 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9S4K9_PHYPA
Length = 616
Score = 167 bits (422), Expect = 4e-40
Identities = 84/140 (60%), Positives = 107/140 (76%)
Frame = +2
Query: 2 NELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGT 181
N+LGY +D +L ++F RFKAVAE+KK V++ DL L+ DEVFQPE +W L +Q+ CG
Sbjct: 420 NQLGYEVDGQELDDVFKRFKAVAEKKKNVSNEDLETLLFDEVFQPETLWSLGLIQVVCGN 479
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
G+ST+TVKL DG +H+ SVGTGPVDAAYKAVD IVK P TLLEYS+N+VTEGIDA+
Sbjct: 480 AGISTATVKLEGPDGAQHIGMSVGTGPVDAAYKAVDTIVKAPVTLLEYSLNSVTEGIDAL 539
Query: 362 ATTRVLIRGDNNYSSTNAVT 421
A TRV IR ++ + T+A T
Sbjct: 540 AHTRVQIRALDSLTVTHAQT 559
[31][TOP]
>UniRef100_A8HXS9 Isopropylmalate synthase (Fragment) n=1 Tax=Chlamydomonas
reinhardtii RepID=A8HXS9_CHLRE
Length = 444
Score = 147 bits (372), Expect = 3e-34
Identities = 68/132 (51%), Positives = 100/132 (75%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY L +L ++F RFKA+A++KK +TD D++AL+SDE+ QP+ +W+LLD+Q+ CGT+G
Sbjct: 253 LGYELSQSELDDVFKRFKALADKKKGITDEDILALMSDELHQPKVIWELLDLQVVCGTMG 312
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
+ T+TV++ DG + VGTGPVDAAYKAVD +V+ A L +YS+++VT+GI+A+A
Sbjct: 313 MPTATVQMKGPDGIARIGVGVGTGPVDAAYKAVDSLVRVEAELSDYSVSSVTQGIEALAH 372
Query: 368 TRVLIRGDNNYS 403
TRV+IR S
Sbjct: 373 TRVMIRPSGKMS 384
[32][TOP]
>UniRef100_A9GW82 2-isopropylmalate synthase n=1 Tax=Sorangium cellulosum 'So ce 56'
RepID=A9GW82_SORC5
Length = 564
Score = 133 bits (334), Expect = 7e-30
Identities = 66/129 (51%), Positives = 93/129 (72%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY LD+ QL+ F FKA+A++KK VTD D+ A+VS Q + ++ L +Q+ CGT
Sbjct: 365 ELGYHLDEAQLAAAFASFKALADKKKHVTDPDIEAIVSTTRAQADDLYTLDALQVACGTT 424
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G+ T+TV+L DG HV ++GTGPVDAAY+A+D IV+ P++LLE+S++AVTEGIDA+
Sbjct: 425 GMPTATVRLRGPDGALHVRAAIGTGPVDAAYRAIDEIVRVPSSLLEFSVHAVTEGIDALG 484
Query: 365 TTRVLIRGD 391
V +R D
Sbjct: 485 EVSVRVRAD 493
[33][TOP]
>UniRef100_Q46K01 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus str.
NATL2A RepID=LEU1_PROMT
Length = 539
Score = 122 bits (307), Expect = 9e-27
Identities = 61/134 (45%), Positives = 94/134 (70%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LGY L+ L++ F RFK +A++K+ +TD DL A+VS++V PEA+++L +Q++CGT
Sbjct: 360 DLGYDLNREDLNDAFARFKDLADRKREITDRDLEAIVSEQVQLPEALFQLKLVQVSCGTS 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
+ T+TV + DG+E A S+GTGPVDA +A+D + +EP L+E+S+ +VTEGIDA+
Sbjct: 420 LMPTATVTVVGEDGEEKTAVSLGTGPVDAVVRALDSLTEEPNELIEFSVKSVTEGIDALG 479
Query: 365 TTRVLIRGDNNYSS 406
+ IR D N S
Sbjct: 480 EVTIRIRRDGNLFS 493
[34][TOP]
>UniRef100_A2C3L7 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus str.
NATL1A RepID=LEU1_PROM1
Length = 539
Score = 122 bits (307), Expect = 9e-27
Identities = 61/134 (45%), Positives = 94/134 (70%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LGY L+ L++ F RFK +A++K+ +TD DL A+VS++V PEA+++L +Q++CGT
Sbjct: 360 DLGYDLNREDLNDAFARFKDLADRKREITDRDLEAIVSEQVQLPEALFQLKLVQVSCGTS 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
+ T+TV + DG+E A S+GTGPVDA +A+D + +EP L+E+S+ +VTEGIDA+
Sbjct: 420 LMPTATVTVVGEDGEEKTAVSLGTGPVDAVVRALDSLTEEPNELIEFSVKSVTEGIDALG 479
Query: 365 TTRVLIRGDNNYSS 406
+ IR D N S
Sbjct: 480 EVTIRIRRDGNLFS 493
[35][TOP]
>UniRef100_Q6UA13 Fiber protein Fb26 (Fragment) n=1 Tax=Gossypium barbadense
RepID=Q6UA13_GOSBA
Length = 128
Score = 122 bits (306), Expect = 1e-26
Identities = 60/77 (77%), Positives = 68/77 (88%)
Frame = +2
Query: 194 TSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIATTR 373
T+TVKL +DG+EHVACSVGTGPVD+AYKA+DLI KEP TLLEYSMNAVTEGIDAIATTR
Sbjct: 1 TATVKLIGADGEEHVACSVGTGPVDSAYKAIDLITKEPVTLLEYSMNAVTEGIDAIATTR 60
Query: 374 VLIRGDNNYSSTNAVTG 424
VLIR + + STN +TG
Sbjct: 61 VLIRAEKSRISTNILTG 77
[36][TOP]
>UniRef100_P48576 2-isopropylmalate synthase n=1 Tax=Synechocystis sp. PCC 6803
RepID=LEU1_SYNY3
Length = 533
Score = 122 bits (305), Expect = 2e-26
Identities = 60/127 (47%), Positives = 89/127 (70%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L D +L+N F RFK VA+++K +TD DL A+V+DE+ QP +++L +Q++CG
Sbjct: 360 ELGFDLSDTELNNAFIRFKEVADKRKEITDWDLEAIVNDEIRQPPELFRLERVQVSCGEP 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
+ T+T+ + G E A ++GTGPVDA YKA++ IV+ P LLEYS+ +VTEGIDA+
Sbjct: 420 SVPTATLTIRTPAGPEETAVAIGTGPVDAVYKAINQIVQLPNELLEYSVTSVTEGIDALG 479
Query: 365 TTRVLIR 385
V +R
Sbjct: 480 KVSVRLR 486
[37][TOP]
>UniRef100_Q4BZE1 2-isopropylmalate synthase n=1 Tax=Crocosphaera watsonii WH 8501
RepID=Q4BZE1_CROWT
Length = 537
Score = 120 bits (301), Expect = 5e-26
Identities = 62/141 (43%), Positives = 94/141 (66%), Gaps = 1/141 (0%)
Frame = +2
Query: 2 NELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGT 181
+ELG+ L D L+N F RFK VA++KK +TD DL A+V+DE+ Q +++L +Q++CG
Sbjct: 359 SELGFELSDNDLNNAFLRFKEVADKKKEITDWDLEAIVNDEIQQAPELFRLELVQVSCGD 418
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
+ST+TV L + +GKE ++GTGPVDA YKA++ +V P L+E+S+ +VT GIDA+
Sbjct: 419 HAVSTATVTLRNPEGKELTDAAIGTGPVDAVYKAINRVVNVPNELIEFSVKSVTAGIDAM 478
Query: 362 ATTRVLIRGD-NNYSSTNAVT 421
+ +R + YS A T
Sbjct: 479 GEVTIRLRHEGRTYSGYAANT 499
[38][TOP]
>UniRef100_A3Z7T3 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. RS9917
RepID=A3Z7T3_9SYNE
Length = 540
Score = 120 bits (301), Expect = 5e-26
Identities = 63/140 (45%), Positives = 95/140 (67%), Gaps = 1/140 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L L F RFK +A++K+ +TD DL A+VS++V QPEA ++L +Q++CG+
Sbjct: 360 ELGYDLSREDLDEAFARFKDLADRKREITDRDLEAIVSEQVQQPEARYQLKLVQVSCGSS 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV LAD +G+E A ++GTGPVDA +A++ + +EP L+E+S+ +VTEGIDA+
Sbjct: 420 LRPTATVTLADEEGREQTAAAIGTGPVDAVCRALNALAEEPNQLVEFSVKSVTEGIDAMG 479
Query: 365 TTRVLIRGDNN-YSSTNAVT 421
+ +R D YS +A T
Sbjct: 480 EVTIRLRRDGALYSGHSADT 499
[39][TOP]
>UniRef100_Q7NI93 2-isopropylmalate synthase n=1 Tax=Gloeobacter violaceus
RepID=LEU1_GLOVI
Length = 538
Score = 120 bits (300), Expect = 6e-26
Identities = 60/137 (43%), Positives = 90/137 (65%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L D L+ F RFK +A++KK V+D D+ A++SDE+ ++L +Q++CG
Sbjct: 358 ELGYELGDADLNRAFLRFKELADKKKTVSDWDIEAVISDEIRLIPEAYRLEQVQVSCGEP 417
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
GL T+TV+L DG E V +VGTGPVDA YKA++ +++ P L+E+S+ +VT GIDA+
Sbjct: 418 GLPTATVRLTGPDGVERVDAAVGTGPVDAVYKAINRLIELPNELIEFSVQSVTAGIDAMG 477
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R D S +A
Sbjct: 478 EVTIRVRQDGRTFSGHA 494
[40][TOP]
>UniRef100_A3IRU3 2-isopropylmalate synthase n=1 Tax=Cyanothece sp. CCY0110
RepID=A3IRU3_9CHRO
Length = 537
Score = 117 bits (294), Expect = 3e-25
Identities = 57/128 (44%), Positives = 88/128 (68%)
Frame = +2
Query: 2 NELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGT 181
NELG+ L + +L+N F RFK VA++KK +TD DL A+V+DE+ Q +++L +Q++CG
Sbjct: 359 NELGFELSETELNNAFLRFKEVADKKKEITDWDLEAIVNDEIQQAPELFRLELVQVSCGD 418
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
T+TV L + +GKE ++GTGPVDA YKA++ +V P L+E+S+ +VT GIDA+
Sbjct: 419 HSAPTATVTLRNPEGKELTDAAIGTGPVDAVYKAINRVVNVPNELIEFSVKSVTAGIDAM 478
Query: 362 ATTRVLIR 385
+ +R
Sbjct: 479 GEVTIRLR 486
[41][TOP]
>UniRef100_Q7VBG1 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus
RepID=LEU1_PROMA
Length = 536
Score = 117 bits (294), Expect = 3e-25
Identities = 61/134 (45%), Positives = 90/134 (67%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L L++ F RFK +A++K+ ++D DL A+VS++V QPEA +KL +Q++CGT
Sbjct: 360 ELGYDLTREDLNDAFARFKDLADRKREISDRDLEAIVSEQVMQPEARFKLHLVQVSCGTA 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV +AD DG E+ A ++GTGPVDA KA+ + E L+E+S+ +VTEGIDA+
Sbjct: 420 LRPTATVTIADQDGIENTAVALGTGPVDAVCKALRSLTNEKNDLIEFSVKSVTEGIDALG 479
Query: 365 TTRVLIRGDNNYSS 406
+ +R D S
Sbjct: 480 EVTIRLRRDGKIFS 493
[42][TOP]
>UniRef100_A9BB43 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus str. MIT
9211 RepID=LEU1_PROM4
Length = 536
Score = 117 bits (294), Expect = 3e-25
Identities = 60/134 (44%), Positives = 89/134 (66%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L L+ F +FK +A++K+ +TD DL A+VS++V QP+A ++L +Q++CGT
Sbjct: 360 ELGYDLTRDDLNEAFAKFKDLADRKREITDRDLEAIVSEQVMQPDARFQLQLVQVSCGTT 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV LAD DG E A ++GTGPVDA KA+D + E L+E+S+ +VTEGIDA+
Sbjct: 420 LKPTATVTLADQDGTEQTAVALGTGPVDAVCKALDSLAGESNELIEFSVKSVTEGIDALG 479
Query: 365 TTRVLIRGDNNYSS 406
+ +R + S
Sbjct: 480 EVTIRLRREGKIFS 493
[43][TOP]
>UniRef100_Q05XR9 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. RS9916
RepID=Q05XR9_9SYNE
Length = 540
Score = 117 bits (293), Expect = 4e-25
Identities = 60/134 (44%), Positives = 89/134 (66%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L L F RFK +A++K+ +TD DL A+VS++V QPEA ++L +Q++CG+
Sbjct: 360 ELGYDLSRDDLDEAFARFKDLADRKREITDRDLEAIVSEQVQQPEARYQLKLVQVSCGSS 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV LAD +G+E A S+GTGPVDA +A++ + P L+E+S+ +VTEGIDA+
Sbjct: 420 LQPTATVTLADEEGQEQTAASIGTGPVDAVCRALNALAGVPNELVEFSVKSVTEGIDAMG 479
Query: 365 TTRVLIRGDNNYSS 406
+ +R D S
Sbjct: 480 EVTIRLRRDGQLFS 493
[44][TOP]
>UniRef100_C1FID7 2-isopropylmalate synthase n=1 Tax=Micromonas sp. RCC299
RepID=C1FID7_9CHLO
Length = 639
Score = 117 bits (293), Expect = 4e-25
Identities = 63/142 (44%), Positives = 94/142 (66%), Gaps = 4/142 (2%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKR-VTDADLIALVSDEVFQPE---AVWKLLDMQIT 172
+LG+ L+ +L+ +F RFK VAEQK V D ++IALV+ Q + WKL ++Q+
Sbjct: 428 QLGFPLEGDELNEMFDRFKLVAEQKTGGVGDDEIIALVTSGAGQGDDTAVTWKLDEVQVV 487
Query: 173 CGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGI 352
CGT+GL T+TVK+ D + +VGTGPVDAAYKA+D + + L+EY++NAV EGI
Sbjct: 488 CGTMGLPTATVKMTGPDAVTRINSAVGTGPVDAAYKAIDGLCRVKVDLVEYTVNAVVEGI 547
Query: 353 DAIATTRVLIRGDNNYSSTNAV 418
+++A TRV IR ++ + A+
Sbjct: 548 ESLAQTRVSIRAKSDQTMPGAM 569
[45][TOP]
>UniRef100_B7FUP6 2-isopropylmalate synthase n=1 Tax=Phaeodactylum tricornutum CCAP
1055/1 RepID=B7FUP6_PHATR
Length = 663
Score = 117 bits (292), Expect = 5e-25
Identities = 67/145 (46%), Positives = 91/145 (62%), Gaps = 5/145 (3%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKR-VTDADLIALVSDEVFQPEAVWKLLDMQITCGT 181
ELGY LD +L+ +F RFK VAE+KK + D DL ALVSD+ +W++ +Q+ G
Sbjct: 451 ELGYDLDTEKLNAVFVRFKQVAERKKGGLEDEDLEALVSDQAGLSNLLWEVTGLQVATGL 510
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
G+ T+TVK+ DG E GTGPVDA YKA+D I+ L Y +N+VTEGI+A+
Sbjct: 511 SGIPTATVKMLGPDGLERYVACTGTGPVDAVYKAIDQIMGVSVRLEAYQLNSVTEGIEAM 570
Query: 362 ATTRVLIR----GDNNYSSTNAVTG 424
ATTRV+I G N+ S ++ TG
Sbjct: 571 ATTRVVIAPLEGGPNDSISIHSQTG 595
[46][TOP]
>UniRef100_C1N4J5 2-isopropylmalate synthase n=1 Tax=Micromonas pusilla CCMP1545
RepID=C1N4J5_9CHLO
Length = 649
Score = 116 bits (291), Expect = 7e-25
Identities = 66/135 (48%), Positives = 87/135 (64%), Gaps = 8/135 (5%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKR-VTDADLIALVSDEVFQ------PEAVWKLLDM 163
+LGY L+ L +F RFK VAEQK V D ++IALV+ E Q A WKL D+
Sbjct: 440 QLGYPLEGDALDEMFNRFKLVAEQKTGGVDDDEIIALVTCEGSQFAGDVDKSASWKLEDV 499
Query: 164 QITCGTLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVD-LIVKEPATLLEYSMNAV 340
Q+ CGT+GL T+TVK+ DG V VG+GPVDA YKA+D ++ L+EYS+NAV
Sbjct: 500 QVVCGTMGLPTATVKMCGPDGMSRVRSEVGSGPVDATYKAIDGIVAAGKVELVEYSVNAV 559
Query: 341 TEGIDAIATTRVLIR 385
EGI+++A TRV +R
Sbjct: 560 VEGIESLAETRVRVR 574
[47][TOP]
>UniRef100_B7JYP4 2-isopropylmalate synthase n=2 Tax=Cyanothece RepID=LEU1_CYAP8
Length = 536
Score = 116 bits (291), Expect = 7e-25
Identities = 61/140 (43%), Positives = 92/140 (65%), Gaps = 1/140 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L D +++N F RFK VA++KK +TD DL A+V+DE+ Q +++L +Q++CG
Sbjct: 360 ELGFELSDTEINNAFLRFKEVADKKKEITDWDLAAIVNDEMQQAPELFRLELVQVSCGDH 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L DG+E ++GTGPVDA YKA++ +V+ P L+E+S+ +VT GIDA+
Sbjct: 420 ACPTATVTLRTPDGQELTDAAIGTGPVDAVYKAINRVVQVPNELIEFSVKSVTAGIDAMG 479
Query: 365 TTRVLIR-GDNNYSSTNAVT 421
+ +R D YS A T
Sbjct: 480 EVTIRLRYEDKIYSGYAANT 499
[48][TOP]
>UniRef100_Q3AYY2 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. CC9902
RepID=LEU1_SYNS9
Length = 540
Score = 116 bits (290), Expect = 9e-25
Identities = 60/137 (43%), Positives = 89/137 (64%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L L F RFK +A++K+ +TD DL A+VS++V QPEA ++L +Q++CG+
Sbjct: 360 ELGYNLTREDLDEAFARFKDLADRKREITDRDLEAIVSEQVQQPEARFQLKFVQVSCGST 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L D +G E +VGTGPVDA +A++ + P L+E+S+ +VTEGIDAI
Sbjct: 420 SRPTATVALMDEEGGERTVSAVGTGPVDAVCRALNCLADVPNDLIEFSVKSVTEGIDAIG 479
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R D + S +A
Sbjct: 480 EVTIRLRRDGSLYSGHA 496
[49][TOP]
>UniRef100_A2C859 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus str. MIT
9303 RepID=LEU1_PROM3
Length = 540
Score = 116 bits (290), Expect = 9e-25
Identities = 61/134 (45%), Positives = 89/134 (66%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L L F RFK +A++K+ +TD DL A+VS++V QPEA ++L +Q++CG+
Sbjct: 360 ELGYDLTREDLDEAFARFKDLADRKRDITDRDLEAIVSEQVQQPEARFQLRLVQVSCGSS 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV LA DG+E A +VGTGPVDA +A++ + EP L+E+S+ +VTEGIDA+
Sbjct: 420 LRPTATVILAQEDGQEQTAAAVGTGPVDAVCRALNALAGEPNELIEFSVKSVTEGIDAMG 479
Query: 365 TTRVLIRGDNNYSS 406
+ +R D S
Sbjct: 480 EVTIRLRRDGQLFS 493
[50][TOP]
>UniRef100_Q0IBI3 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. CC9311
RepID=LEU1_SYNS3
Length = 540
Score = 115 bits (289), Expect = 1e-24
Identities = 62/140 (44%), Positives = 94/140 (67%), Gaps = 1/140 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L L + F RFK +A++K+ +TD DL ++VS +V QP+A ++L +Q++CG+
Sbjct: 360 ELGYDLSREDLDDAFARFKDLADRKREITDRDLESIVSVQVQQPDAKYQLKLVQVSCGSS 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV LAD +G+E A SVGTGPVDA ++++ + EP L+E+S+ +VTEGIDA+
Sbjct: 420 LQPTATVTLADENGQEQTAASVGTGPVDAVCRSLNQLAGEPNELVEFSVKSVTEGIDAMG 479
Query: 365 TTRVLIRGDNN-YSSTNAVT 421
+ +R D YS +A T
Sbjct: 480 DVTIRLRRDGQLYSGHSAHT 499
[51][TOP]
>UniRef100_A4CVP9 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. WH 7805
RepID=A4CVP9_SYNPV
Length = 540
Score = 115 bits (288), Expect = 1e-24
Identities = 58/137 (42%), Positives = 91/137 (66%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L L + F RFK +A++K+ +TD DL A+VS++V QP+A ++L +Q++CG+
Sbjct: 360 ELGYDLSREDLDDAFARFKELADRKRDITDRDLEAIVSEQVQQPDARYQLTSVQVSCGSN 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L D +G+E ++GTGPVDA +A++ + EP L+E+S+ +VTEGIDA+
Sbjct: 420 LQPTATVTLLDEEGQEQSEAAIGTGPVDAVCRALNALAGEPNELVEFSVKSVTEGIDAMG 479
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R D S +A
Sbjct: 480 EVTIRLRRDGQLFSGHA 496
[52][TOP]
>UniRef100_B1XLQ9 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. PCC 7002
RepID=LEU1_SYNP2
Length = 533
Score = 115 bits (287), Expect = 2e-24
Identities = 58/137 (42%), Positives = 87/137 (63%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L D L+ F RFK +A++KK +TD DL A+V DE QP +++L +Q++CG
Sbjct: 360 ELGFDLSDNDLNKAFLRFKDLADKKKEITDWDLEAIVKDETQQPPELFRLELVQVSCGDH 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+T+ + GKE ++GTGPVDA YKA++ +V+ P L+EYS+ +VT GIDAI
Sbjct: 420 AQPTATITIRTPGGKELTDAAIGTGPVDAIYKAINRVVQVPNELIEYSVQSVTAGIDAIG 479
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R + S +A
Sbjct: 480 EVTIRLRHEGRIYSGHA 496
[53][TOP]
>UniRef100_Q065B6 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. BL107
RepID=Q065B6_9SYNE
Length = 540
Score = 114 bits (286), Expect = 3e-24
Identities = 60/137 (43%), Positives = 89/137 (64%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L L F RFK +A++K+ +TD DL A+VS++V QPEA ++L +Q++CG+
Sbjct: 360 ELGYNLTRDDLDEAFARFKDLADRKREITDRDLEAIVSEQVQQPEARFQLKFVQVSCGSS 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L D +G E +VGTGPVDA +A++ + P L+E+S+ +VTEGIDAI
Sbjct: 420 SRPTATVTLIDEEGGESTGSAVGTGPVDAVCRALNGLADVPNDLIEFSVKSVTEGIDAIG 479
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R D + S +A
Sbjct: 480 EVTIRLRRDGSLYSGHA 496
[54][TOP]
>UniRef100_B1WQQ4 2-isopropylmalate synthase n=1 Tax=Cyanothece sp. ATCC 51142
RepID=LEU1_CYAA5
Length = 537
Score = 114 bits (286), Expect = 3e-24
Identities = 57/135 (42%), Positives = 88/135 (65%)
Frame = +2
Query: 2 NELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGT 181
+ELG+ L + L+N F RFK VA++KK +TD DL A+V+DE+ Q +++L +Q++CG
Sbjct: 359 DELGFELSERDLNNAFLRFKEVADKKKEITDWDLEAIVNDEIQQAPELFRLELVQVSCGD 418
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
T+TV L +GKE ++GTGPVDA YKA++ +V P L+E+S+ +VT GIDA+
Sbjct: 419 HSAPTATVTLRTPEGKELTDAAIGTGPVDAVYKAINRVVNVPNELIEFSVKSVTAGIDAM 478
Query: 362 ATTRVLIRGDNNYSS 406
+ +R + S
Sbjct: 479 GEVTIRLRHEGRIYS 493
[55][TOP]
>UniRef100_A9AZM4 2-isopropylmalate synthase n=1 Tax=Herpetosiphon aurantiacus ATCC
23779 RepID=A9AZM4_HERA2
Length = 555
Score = 114 bits (284), Expect = 4e-24
Identities = 55/126 (43%), Positives = 84/126 (66%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY D+ +++LF RFK VA++KK V D D+ AL+SDE +P V++L +Q G
Sbjct: 347 ELGYSFDEATINHLFARFKDVADRKKYVDDRDVEALISDEAGRPSPVYELEHVQFASGVN 406
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
+ T+TV++ +G+ + + GTGPVDA Y A++ +V P TLLE+++NA+TEGIDA+
Sbjct: 407 AIPTATVRMRGPNGEVKIESAQGTGPVDAVYSAINKVVLTPVTLLEFAVNAITEGIDAVG 466
Query: 365 TTRVLI 382
V +
Sbjct: 467 EVSVKV 472
[56][TOP]
>UniRef100_B8BRI7 Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335
RepID=B8BRI7_THAPS
Length = 658
Score = 114 bits (284), Expect = 4e-24
Identities = 64/139 (46%), Positives = 88/139 (63%), Gaps = 1/139 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKR-VTDADLIALVSDEVFQPEAVWKLLDMQITCGT 181
E+GY LD +L+ +F RFK VAE+KK + D DL +LV D+ +WK+ +Q T G
Sbjct: 447 EMGYDLDMDKLNAVFARFKEVAEKKKGGLDDDDLESLVMDQSQSTNELWKVTGLQTTTGI 506
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
G+ TSTVK+ DG E + GTGPVDA YKA+D I+ L YSMN+V EGI+A+
Sbjct: 507 SGIPTSTVKMMGPDGVERFVSATGTGPVDAVYKAIDQIMGVSVELESYSMNSVNEGIEAL 566
Query: 362 ATTRVLIRGDNNYSSTNAV 418
A+TRV+I + N + + V
Sbjct: 567 ASTRVVIVPNANGPNDSVV 585
[57][TOP]
>UniRef100_A5GM47 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. WH 7803
RepID=LEU1_SYNPW
Length = 540
Score = 114 bits (284), Expect = 4e-24
Identities = 58/137 (42%), Positives = 91/137 (66%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L L + F RFK +A++K+ +TD DL A+VS++V QP+A ++L +Q++CG+
Sbjct: 360 ELGYDLSREDLDDAFARFKELADRKRDITDRDLEAIVSEQVQQPDARYQLKLVQVSCGSS 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L D +G+E ++GTGPVDA +A++ + EP L+E+S+ +VTEGIDA+
Sbjct: 420 LQPTATVTLLDEEGQEQSEAAIGTGPVDAVCRALNALAGEPNELVEFSVKSVTEGIDAMG 479
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R D S +A
Sbjct: 480 EVTIRLRRDGQLFSGHA 496
[58][TOP]
>UniRef100_Q2JLJ8 2-isopropylmalate synthase n=1 Tax=Synechococcus sp.
JA-2-3B'a(2-13) RepID=Q2JLJ8_SYNJB
Length = 546
Score = 113 bits (282), Expect = 7e-24
Identities = 57/137 (41%), Positives = 88/137 (64%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L + L+ F RFK +A++KK ++D DL A+V+DE +++L +Q+ CG
Sbjct: 369 ELGFELSEQDLNKAFLRFKELADKKKEISDLDLEAIVNDETRPVPELYRLEHVQVVCGNR 428
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV+L +G+E V +VGTGPVDA YKA++ IV P L+E+S+ +VT GIDAI
Sbjct: 429 EAPTATVRLVTPEGEERVDAAVGTGPVDAVYKAINRIVNIPNKLIEFSVQSVTAGIDAIG 488
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R ++ S +A
Sbjct: 489 EVTIRLRHEDRIFSGHA 505
[59][TOP]
>UniRef100_Q7TUV5 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus str. MIT
9313 RepID=LEU1_PROMM
Length = 540
Score = 113 bits (282), Expect = 7e-24
Identities = 60/134 (44%), Positives = 88/134 (65%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L L F RFK +A++K+ +TD DL A+VS++V Q EA ++L +Q++CG+
Sbjct: 360 ELGYDLTREDLDEAFARFKDLADRKRDITDRDLEAIVSEQVQQSEARFQLRLVQVSCGSS 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV LA DG+E A +VGTGPVDA +A++ + EP L+E+S+ +VTEGIDA+
Sbjct: 420 LRPTATVILAQEDGQEQTAAAVGTGPVDAVCRALNALAGEPNELIEFSVKSVTEGIDAMG 479
Query: 365 TTRVLIRGDNNYSS 406
+ +R D S
Sbjct: 480 EVTIRLRRDGQLFS 493
[60][TOP]
>UniRef100_B7KJX8 2-isopropylmalate synthase n=1 Tax=Cyanothece sp. PCC 7424
RepID=LEU1_CYAP7
Length = 536
Score = 113 bits (282), Expect = 7e-24
Identities = 57/137 (41%), Positives = 90/137 (65%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L + L+ F RFK VA++KK +TD DL A+V+DE+ Q V++L +Q++CG
Sbjct: 360 ELGFELSETDLNKAFLRFKEVADKKKEITDWDLEAIVNDEIQQAPEVFRLELVQVSCGDQ 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L +G+E + ++GTGPVDA YKA++ +V P L+E+S+ +VT GIDA+
Sbjct: 420 ARPTATVILRGPEGQELMDAAIGTGPVDAVYKAINRVVNVPNQLIEFSVKSVTAGIDAMG 479
Query: 365 TTRVLIRGDNNYSSTNA 415
+ ++ +N S +A
Sbjct: 480 EVTIRLKYENRIFSGHA 496
[61][TOP]
>UniRef100_B9P2F2 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus str. MIT
9202 RepID=B9P2F2_PROMA
Length = 546
Score = 112 bits (281), Expect = 1e-23
Identities = 61/141 (43%), Positives = 93/141 (65%), Gaps = 2/141 (1%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
E+GY L L++ F RFK +A++K+ +TD DL A+VS++V PEA ++L +Q++CG
Sbjct: 360 EMGYDLSREDLNDAFTRFKDLADRKREITDRDLEAIVSEQVQLPEAKFQLSLVQVSCGNA 419
Query: 185 GLSTSTVKLADS-DGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
T+T+ L ++ D E A S+GTGPVDA +A++ + K P L+E+S+ +VTEGIDA+
Sbjct: 420 SKPTATISLINTEDDSEDTAVSIGTGPVDAVCEALNKLAKVPNELIEFSVKSVTEGIDAL 479
Query: 362 ATTRVLIRGDNN-YSSTNAVT 421
+ IR DN YS +A T
Sbjct: 480 GEVTIRIRRDNKIYSGHSADT 500
[62][TOP]
>UniRef100_Q31AF9 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus str. MIT
9312 RepID=LEU1_PROM9
Length = 546
Score = 112 bits (281), Expect = 1e-23
Identities = 62/141 (43%), Positives = 93/141 (65%), Gaps = 2/141 (1%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
E+GY L L++ F RFK +A++K+ +TD DL A+VS++V PEA ++L +Q++CG
Sbjct: 360 EMGYDLSREDLNDAFARFKDLADRKREITDRDLEAIVSEQVQLPEAKFQLCLVQVSCGNA 419
Query: 185 GLSTSTVKLADS-DGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
T+T+ L ++ D E A SVGTGPVDA +A++ + K P L+E+S+ +VTEGIDA+
Sbjct: 420 SKPTATITLLNTADNTEDTAVSVGTGPVDAVCEALNKLAKVPNELIEFSVKSVTEGIDAL 479
Query: 362 ATTRVLIRGDNN-YSSTNAVT 421
+ IR DN YS +A T
Sbjct: 480 GEVTIRIRRDNKIYSGHSADT 500
[63][TOP]
>UniRef100_A8G5D5 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus str. MIT
9215 RepID=LEU1_PROM2
Length = 546
Score = 112 bits (281), Expect = 1e-23
Identities = 61/141 (43%), Positives = 93/141 (65%), Gaps = 2/141 (1%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
E+GY L L++ F RFK +A++K+ +TD DL A+VS++V PEA ++L +Q++CG
Sbjct: 360 EMGYDLSREDLNDAFARFKDLADRKREITDRDLEAIVSEQVQLPEAKFQLSLVQVSCGNA 419
Query: 185 GLSTSTVKLADS-DGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
T+T+ L ++ D E A S+GTGPVDA +A++ + K P L+E+S+ +VTEGIDA+
Sbjct: 420 SKPTATISLINTEDNSEDTAVSIGTGPVDAVCEALNKLAKVPNELIEFSVKSVTEGIDAL 479
Query: 362 ATTRVLIRGDNN-YSSTNAVT 421
+ IR DN YS +A T
Sbjct: 480 GEVTIRIRRDNKIYSGHSADT 500
[64][TOP]
>UniRef100_Q2JSL4 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. JA-3-3Ab
RepID=Q2JSL4_SYNJA
Length = 546
Score = 112 bits (280), Expect = 1e-23
Identities = 57/137 (41%), Positives = 88/137 (64%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L + L+ F RFK +A++KK +TD DL A+V+DE +++L +Q+ CG
Sbjct: 369 ELGFELSEQDLNKAFLRFKELADKKKEITDLDLEAIVNDETRPVPDLYRLEHVQVVCGNH 428
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV+L +G+E V +VGTGPVDA YKA++ IV P L+E+S+ +VT GIDA+
Sbjct: 429 ETPTATVRLITPEGEERVDAAVGTGPVDAVYKAINRIVNIPNKLIEFSVQSVTAGIDAMG 488
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R ++ S +A
Sbjct: 489 EVTIRLRHEDRVFSGHA 505
[65][TOP]
>UniRef100_A0ZGD0 2-isopropylmalate synthase n=1 Tax=Nodularia spumigena CCY9414
RepID=A0ZGD0_NODSP
Length = 534
Score = 112 bits (280), Expect = 1e-23
Identities = 57/137 (41%), Positives = 90/137 (65%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L + +L+ F +FK VA++KK +TD DL A+V+DE+ Q ++++ +QI+CG
Sbjct: 360 ELGFELSETELNKAFVKFKDVADKKKEITDWDLEAIVNDEIQQAPDLFRVELVQISCGNN 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L G+E ++GTGPVDA YKA++ +V P L+E+S+ +VTEGIDA+
Sbjct: 420 AQPTATVTLRTPAGEELTDAAIGTGPVDAVYKAINRVVNVPNQLIEFSVQSVTEGIDALG 479
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R D+ S +A
Sbjct: 480 EVTIRLRHDSRVFSGHA 496
[66][TOP]
>UniRef100_A2BRP4 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus str.
AS9601 RepID=LEU1_PROMS
Length = 546
Score = 112 bits (280), Expect = 1e-23
Identities = 61/141 (43%), Positives = 93/141 (65%), Gaps = 2/141 (1%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
E+GY L L++ F RFK +A++K+ +TD DL A+VS++V PEA ++L +Q++CG
Sbjct: 360 EMGYDLSREDLNDAFARFKDLADRKREITDRDLEAIVSEQVQLPEAKFQLSLVQVSCGNA 419
Query: 185 GLSTSTVKLADS-DGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
T+T+ L ++ D E A S+GTGPVDA +A++ + K P L+E+S+ +VTEGIDA+
Sbjct: 420 SKPTATISLLNTEDNTEDTAVSIGTGPVDAVCEALNKLAKVPNELIEFSVKSVTEGIDAL 479
Query: 362 ATTRVLIRGDNN-YSSTNAVT 421
+ IR DN YS +A T
Sbjct: 480 GEVTIRIRRDNKIYSGHSADT 500
[67][TOP]
>UniRef100_A3PDH0 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus str. MIT
9301 RepID=LEU1_PROM0
Length = 546
Score = 112 bits (280), Expect = 1e-23
Identities = 61/141 (43%), Positives = 93/141 (65%), Gaps = 2/141 (1%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
E+GY L L++ F RFK +A++K+ +TD DL A+VS++V PEA ++L +Q++CG
Sbjct: 360 EMGYDLSREDLNDAFARFKDLADRKREITDRDLEAIVSEQVQLPEAKFQLSLVQVSCGNA 419
Query: 185 GLSTSTVKLADS-DGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
T+T+ L ++ D E A S+GTGPVDA +A++ + K P L+E+S+ +VTEGIDA+
Sbjct: 420 SKPTATISLLNTEDNTEDTAVSIGTGPVDAVCEALNKLAKVPNELIEFSVKSVTEGIDAL 479
Query: 362 ATTRVLIRGDNN-YSSTNAVT 421
+ IR DN YS +A T
Sbjct: 480 GEVTIRIRRDNKIYSGHSADT 500
[68][TOP]
>UniRef100_Q7U892 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. WH 8102
RepID=LEU1_SYNPX
Length = 540
Score = 112 bits (279), Expect = 2e-23
Identities = 58/137 (42%), Positives = 90/137 (65%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L L F RFK +A++K+ +TD DL A+VS++V QPEA ++L +Q++CGT
Sbjct: 360 ELGYDLTREDLDEAFARFKDLADRKREITDRDLEAIVSEQVQQPEARYQLQLVQVSCGTR 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L++ +G + +VGTGPVDA +A++ + P L+E+S+ +VTEGIDA+
Sbjct: 420 LKPTATVALSEENGPDQTVSAVGTGPVDAVCRALNQLAGVPNELIEFSVKSVTEGIDAMG 479
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R D + S +A
Sbjct: 480 EVTIRLRRDGSLYSGHA 496
[69][TOP]
>UniRef100_B4WG76 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. PCC 7335
RepID=B4WG76_9SYNE
Length = 560
Score = 111 bits (277), Expect = 3e-23
Identities = 57/137 (41%), Positives = 87/137 (63%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L D +L+ F RFK +A++KK ++D DL A+V+DE Q +K +Q++CG+
Sbjct: 381 ELGFDLGDQELNKAFLRFKDIADKKKEISDRDLEAIVNDETLQVAEHFKAELIQVSCGSN 440
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+T+ + DG+E S+GTGPVDA Y+A++ IV P L+EYS+ +VT GIDA+
Sbjct: 441 AQPTATITIRMPDGQELTDASIGTGPVDAIYRAINRIVDIPNDLIEYSVQSVTAGIDAMG 500
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R D S +A
Sbjct: 501 EVTIRLRHDERIYSGHA 517
[70][TOP]
>UniRef100_B4B3Y2 2-isopropylmalate synthase n=1 Tax=Cyanothece sp. PCC 7822
RepID=B4B3Y2_9CHRO
Length = 535
Score = 111 bits (277), Expect = 3e-23
Identities = 55/137 (40%), Positives = 91/137 (66%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L + +L+ F RFK VA+++K +TD DL A+V+DE+ +++L +Q++CG
Sbjct: 360 ELGFELTETELNKAFVRFKEVADKRKEITDWDLEAIVNDEIHVAPEIFRLELVQVSCGDQ 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L +G+E + ++GTGPVDA YKA++ +V P L+E+S+ +VTEGIDA+
Sbjct: 420 ARPTATVILKGPNGEELMDAAIGTGPVDAVYKAINRVVNVPNQLIEFSVKSVTEGIDAMG 479
Query: 365 TTRVLIRGDNNYSSTNA 415
+ ++ +N S +A
Sbjct: 480 EVTIRLKYENRTFSGHA 496
[71][TOP]
>UniRef100_B4VRZ4 2-isopropylmalate synthase n=1 Tax=Microcoleus chthonoplastes PCC
7420 RepID=B4VRZ4_9CYAN
Length = 539
Score = 110 bits (276), Expect = 4e-23
Identities = 58/137 (42%), Positives = 90/137 (65%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L + +L+ F RFK VA++KK V+D DL ALV+DE+ Q ++ L +Q++CG
Sbjct: 360 ELGFDLSETELNKAFVRFKEVADKKKDVSDWDLEALVNDEISQVPELFHLELVQVSCGDH 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L +G+E + ++GTGPVDA YKA++ +V P L+EYS+ +VT GIDA+
Sbjct: 420 ARPTATVTLRTPEGEELMDAAIGTGPVDAVYKAINRVVNVPNELIEYSVQSVTAGIDALG 479
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R ++ S +A
Sbjct: 480 EVTIRLRYNSRVFSGHA 496
[72][TOP]
>UniRef100_Q3MBA3 2-isopropylmalate synthase n=1 Tax=Anabaena variabilis ATCC 29413
RepID=LEU1_ANAVT
Length = 531
Score = 110 bits (276), Expect = 4e-23
Identities = 55/137 (40%), Positives = 91/137 (66%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L + +L+ F +FK VA++KK ++D DL A+V+DE+ Q ++++ +Q++CG+
Sbjct: 360 ELGFELSETELNKAFVKFKEVADKKKEISDWDLEAIVNDEIQQAPDLFRVELVQVSCGSN 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L DG+E ++GTGPVDA YKA++ +V P L+E+S+ +VT GIDAI
Sbjct: 420 ARPTATVTLRTPDGEELTDAAIGTGPVDAVYKAINRVVNVPNQLIEFSVQSVTAGIDAIG 479
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R ++ S +A
Sbjct: 480 EVTIRLRYESRVFSGHA 496
[73][TOP]
>UniRef100_P48575 2-isopropylmalate synthase n=1 Tax=Nostoc sp. PCC 7120
RepID=LEU1_ANASP
Length = 531
Score = 110 bits (276), Expect = 4e-23
Identities = 55/137 (40%), Positives = 91/137 (66%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L + +L+ F +FK VA++KK ++D DL A+V+DE+ Q ++++ +Q++CG+
Sbjct: 360 ELGFELSETELNKAFVKFKEVADKKKEISDWDLEAIVNDEIQQAPDLFRVELVQVSCGSN 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L DG+E ++GTGPVDA YKA++ +V P L+E+S+ +VT GIDAI
Sbjct: 420 ARPTATVTLRTPDGEELTDAAIGTGPVDAVYKAINRVVNVPNQLIEFSVQSVTAGIDAIG 479
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R ++ S +A
Sbjct: 480 EVTIRLRYESRVFSGHA 496
[74][TOP]
>UniRef100_B2IU89 2-isopropylmalate synthase n=1 Tax=Nostoc punctiforme PCC 73102
RepID=B2IU89_NOSP7
Length = 534
Score = 110 bits (274), Expect = 6e-23
Identities = 56/137 (40%), Positives = 90/137 (65%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L D +L+ F RFK VA++KK ++D DL A+V+DE+ Q ++++ +Q++CG+
Sbjct: 360 ELGFELSDTELNKAFVRFKEVADKKKDISDWDLEAIVNDEIQQAPDLFRVELVQVSCGSN 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L G+E ++GTGPVDA YKA++ +V P L+E+S+ +VT GIDAI
Sbjct: 420 ARPTATVTLRTPKGEELTDAAIGTGPVDAVYKAINRVVNVPNELIEFSVQSVTAGIDAIG 479
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R ++ S +A
Sbjct: 480 EVTIRLRYESKVFSGHA 496
[75][TOP]
>UniRef100_A5GRZ0 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. RCC307
RepID=LEU1_SYNR3
Length = 537
Score = 110 bits (274), Expect = 6e-23
Identities = 58/137 (42%), Positives = 89/137 (64%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY LD L++ F RFK +A++K+ +TD DL A+V Q EA ++L +Q++CG
Sbjct: 360 ELGYQLDGDDLNDAFARFKELADRKREITDRDLEAIVRQNAQQIEAYYQLAGVQVSCGRD 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
+T+TV L SDG+E ++GTGPVDA +A++ +V+ P L+E+S+ +VTEGIDA+
Sbjct: 420 LRATATVTLRTSDGEECSQAAIGTGPVDAVCQALNGLVQVPNELVEFSVKSVTEGIDAMG 479
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R D S +A
Sbjct: 480 EVTIRLRQDGRLYSGHA 496
[76][TOP]
>UniRef100_Q7V121 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus subsp.
pastoris str. CCMP1986 RepID=LEU1_PROMP
Length = 546
Score = 109 bits (273), Expect = 8e-23
Identities = 59/141 (41%), Positives = 93/141 (65%), Gaps = 2/141 (1%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
E+GY L L++ F RFK +A++K+ +TD DL A+VS++V PE+ ++L +Q++CG+
Sbjct: 360 EMGYDLSREDLNDAFARFKELADRKREITDRDLEAIVSEQVQLPESKFQLSHVQVSCGST 419
Query: 185 GLSTSTVKLADS-DGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
T+TV L ++ D E A ++GTGPVDA +A++ + K P L+E+S+ +VTEGIDA+
Sbjct: 420 SKPTATVTLINTEDHTEDTAVAIGTGPVDAVCEALNALTKVPNELIEFSVKSVTEGIDAL 479
Query: 362 ATTRVLIRGDNN-YSSTNAVT 421
+ IR N YS +A T
Sbjct: 480 GEVTIRIRNKNKIYSGHSADT 500
[77][TOP]
>UniRef100_D0CH66 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. WH 8109
RepID=D0CH66_9SYNE
Length = 540
Score = 109 bits (272), Expect = 1e-22
Identities = 58/137 (42%), Positives = 89/137 (64%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L L F RFK +A++K+ +TD DL A+VS++V QPEA ++L +Q++CG+
Sbjct: 360 ELGYDLTREDLDEAFARFKELADRKREITDRDLEAIVSEQVQQPEARFQLKLVQVSCGSS 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L+D +G E +VGTGPVDA +A++ + P L+E+S+ +VTEGIDA+
Sbjct: 420 LRPTATVTLSDEEGSETTGSAVGTGPVDAVCRALNDLAGVPNELIEFSVKSVTEGIDAMG 479
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R + S +A
Sbjct: 480 DVTIRLRRNGALYSGHA 496
[78][TOP]
>UniRef100_Q3AIA2 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. CC9605
RepID=LEU1_SYNSC
Length = 540
Score = 108 bits (270), Expect = 2e-22
Identities = 58/137 (42%), Positives = 88/137 (64%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L L F RFK +A++K+ +TD DL A+VS++V QPEA ++L +Q++CG+
Sbjct: 360 ELGYDLTREDLDEAFARFKELADRKREITDRDLEAIVSEQVQQPEARFQLKLVQVSCGSS 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L D +G E +VGTGPVDA +A++ + P L+E+S+ +VTEGIDA+
Sbjct: 420 LRPTATVTLLDEEGSETTGSAVGTGPVDAVCRALNDLAGVPNELIEFSVKSVTEGIDAMG 479
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R + S +A
Sbjct: 480 DVTIRLRRNGALYSGHA 496
[79][TOP]
>UniRef100_B5W9X6 LeuA allosteric (Dimerisation) domain n=1 Tax=Arthrospira maxima
CS-328 RepID=B5W9X6_SPIMA
Length = 272
Score = 108 bits (269), Expect = 2e-22
Identities = 56/137 (40%), Positives = 86/137 (62%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L D +++ F RFK VA++KK VT+ D+ A+V+DE+ Q +++L +Q++CG
Sbjct: 96 ELGFDLSDDEINKAFVRFKDVADKKKEVTNWDIEAIVNDEIQQTPELFRLELVQVSCGNN 155
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L G+E + GTGPVDA YKA++ +V P L+E+S+ +VT GIDAI
Sbjct: 156 ARPTATVTLRTPQGQELTDAATGTGPVDAVYKAINRVVNVPNELIEFSVQSVTAGIDAIG 215
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R S +A
Sbjct: 216 EVTIRLRYQGRVFSGHA 232
[80][TOP]
>UniRef100_Q01FR2 Putative 2-isopropylmalate synthase (ISS) n=1 Tax=Ostreococcus
tauri RepID=Q01FR2_OSTTA
Length = 586
Score = 107 bits (268), Expect = 3e-22
Identities = 55/128 (42%), Positives = 82/128 (64%), Gaps = 1/128 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKR-VTDADLIALVSDEVFQPEAVWKLLDMQITCGT 181
+LG ++ L +F RFK VAE K V D +L+A+V D + W L +Q+ CGT
Sbjct: 391 QLGVPMEGAALDEVFNRFKLVAETKLGGVNDDELLAIVRDGESVQDPAWSLETVQVVCGT 450
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
GL T+TV++ + DG +H++ VGTGPVDAA+KA+D +V L EY + AVT+GI+++
Sbjct: 451 TGLPTATVRMNNRDGTQHISAVVGTGPVDAAFKAIDALVGLDVVLTEYRVTAVTKGINSM 510
Query: 362 ATTRVLIR 385
A T + I+
Sbjct: 511 AETTITIK 518
[81][TOP]
>UniRef100_B0JGK2 2-isopropylmalate synthase n=1 Tax=Microcystis aeruginosa NIES-843
RepID=LEU1_MICAN
Length = 533
Score = 107 bits (267), Expect = 4e-22
Identities = 55/137 (40%), Positives = 86/137 (62%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L + +L+N F +FK +A++KK +TD DL A+V+DE+ ++L +Q++CG
Sbjct: 361 ELGFELSETELNNAFIQFKEMADRKKEITDRDLEAIVNDEIDTVPDHFRLELVQVSCGNS 420
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV + DG E ++GTGPVDA KA+D +VK P L+ +S+ VTEGIDA+
Sbjct: 421 ARPTATVTIRTPDGSELSDAAIGTGPVDALCKAIDRVVKIPNELISFSVREVTEGIDALG 480
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R + S +A
Sbjct: 481 EVTIRLRYEGRTYSAHA 497
[82][TOP]
>UniRef100_B8G7X2 2-isopropylmalate synthase n=1 Tax=Chloroflexus aggregans DSM 9485
RepID=B8G7X2_CHLAD
Length = 568
Score = 106 bits (265), Expect = 7e-22
Identities = 53/127 (41%), Positives = 84/127 (66%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
E GY L+D + ++F RFK + ++KK+V D D+ AL++ E+ ++KL +Q G
Sbjct: 353 EKGYKLNDDEFQHVFARFKDLCDRKKKVDDRDIEALIAGEMQHTPELYKLDHVQYASGVG 412
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
+ T+TV+L DG+ V + GTGPVDA Y+A++ I++ P L+E+S+NA+TEG+DA+A
Sbjct: 413 MIPTATVRLIGPDGQAKVDSAQGTGPVDAVYQAINRIIQRPNELIEFSINAITEGLDAVA 472
Query: 365 TTRVLIR 385
V IR
Sbjct: 473 EVTVRIR 479
[83][TOP]
>UniRef100_A4RRV6 Predicted protein n=1 Tax=Ostreococcus lucimarinus CCE9901
RepID=A4RRV6_OSTLU
Length = 624
Score = 106 bits (265), Expect = 7e-22
Identities = 55/128 (42%), Positives = 80/128 (62%), Gaps = 1/128 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKR-VTDADLIALVSDEVFQPEAVWKLLDMQITCGT 181
+LG ++ L +F RFK VAE K V D +L+A+V D + W L +Q+ CGT
Sbjct: 429 QLGVPMEGDALDEVFNRFKLVAETKLGGVNDDELLAIVRDGESVQDPAWSLETVQVVCGT 488
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
GL T+TVK+ DG H++ VGTGPVDAA+KA+D +V L EY + AVT+GI+++
Sbjct: 489 TGLPTATVKMLAKDGTVHISAVVGTGPVDAAFKAIDALVGLDVVLTEYRVTAVTKGINSL 548
Query: 362 ATTRVLIR 385
A T + ++
Sbjct: 549 AETTITVK 556
[84][TOP]
>UniRef100_Q5N5T3 2-isopropylmalate synthase n=1 Tax=Synechococcus elongatus PCC 6301
RepID=Q5N5T3_SYNP6
Length = 540
Score = 106 bits (264), Expect = 9e-22
Identities = 55/134 (41%), Positives = 85/134 (63%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L + L+ F RFK +A++K+ VTD DL A+V+DE Q ++KL +Q++ G
Sbjct: 362 ELGYDLGEDDLNRAFLRFKELADKKREVTDRDLEAIVNDETQQAPELFKLELVQVSAGDH 421
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L +G+E ++GTGPVDA Y+A++ +V P L+E+S+ +VT GIDAI
Sbjct: 422 ARPTATVTLRTPEGEELTDAAIGTGPVDAIYRAINRVVNIPNELIEFSVKSVTAGIDAIG 481
Query: 365 TTRVLIRGDNNYSS 406
+ +R ++ S
Sbjct: 482 EVTIRLRHEDRIFS 495
[85][TOP]
>UniRef100_Q31NC9 2-isopropylmalate synthase n=1 Tax=Synechococcus elongatus PCC 7942
RepID=Q31NC9_SYNE7
Length = 540
Score = 106 bits (264), Expect = 9e-22
Identities = 55/134 (41%), Positives = 85/134 (63%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L + L+ F RFK +A++K+ VTD DL A+V+DE Q ++KL +Q++ G
Sbjct: 362 ELGYDLGEDDLNRAFLRFKELADKKREVTDRDLEAIVNDETQQAPELFKLELVQVSAGDH 421
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L +G+E ++GTGPVDA Y+A++ +V P L+E+S+ +VT GIDAI
Sbjct: 422 ARPTATVTLRTPEGEELTDAAIGTGPVDAIYRAINRVVNIPNELIEFSVKSVTAGIDAIG 481
Query: 365 TTRVLIRGDNNYSS 406
+ +R ++ S
Sbjct: 482 EVTIRLRHEDRIFS 495
[86][TOP]
>UniRef100_A8YBI6 LeuA protein n=1 Tax=Microcystis aeruginosa PCC 7806
RepID=A8YBI6_MICAE
Length = 533
Score = 106 bits (264), Expect = 9e-22
Identities = 55/137 (40%), Positives = 84/137 (61%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L + +L+N F +FK +A++KK +TD DL A+V+DE+ ++L +Q+ CG
Sbjct: 361 ELGFELSETELNNAFIQFKEMADRKKEITDRDLEAIVNDEIDTVPDHFRLELVQVACGNN 420
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV + DG E ++GTGPVDA KA+D +VK P L+ +S+ VTEGIDA+
Sbjct: 421 ARPTATVTIRTPDGSELSDAAIGTGPVDALCKAIDRVVKIPNELISFSVREVTEGIDALG 480
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R + S A
Sbjct: 481 EVTIRLRYEGRTYSARA 497
[87][TOP]
>UniRef100_A5UUP9 2-isopropylmalate synthase n=1 Tax=Roseiflexus sp. RS-1
RepID=A5UUP9_ROSS1
Length = 556
Score = 105 bits (263), Expect = 1e-21
Identities = 56/131 (42%), Positives = 79/131 (60%), Gaps = 1/131 (0%)
Frame = +2
Query: 8 LGYVLD-DGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+GY D + + + +F RFK + ++KK V D DL L + +++L +Q+TCGT
Sbjct: 347 MGYEFDSEEEFNQVFQRFKELCDKKKVVDDRDLEVLATGGSLHTPDLYRLDHVQVTCGTG 406
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
+TV++ D DG H + GTGPVDA YKA+D IV P L+E+S+ AVTEGIDA+A
Sbjct: 407 VTPVATVRITDPDGNTHTTAAHGTGPVDAIYKAIDKIVGRPNELIEFSIKAVTEGIDAVA 466
Query: 365 TTRVLIRGDNN 397
V IR N
Sbjct: 467 EVSVRIREPGN 477
[88][TOP]
>UniRef100_A0YYJ6 2-isopropylmalate synthase n=1 Tax=Lyngbya sp. PCC 8106
RepID=A0YYJ6_9CYAN
Length = 536
Score = 105 bits (263), Expect = 1e-21
Identities = 52/137 (37%), Positives = 87/137 (63%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L D ++ F +FK +A++KK +TD DL ++ ++E+ Q +++L +Q++CG
Sbjct: 362 ELGFELSDSDINKAFIKFKDLADKKKEITDWDLESIANNEIHQAPELFRLELVQVSCGDH 421
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L G+E + ++GTGPVDA YKA++ +V P L+E+S+ +VT GIDAI
Sbjct: 422 ARPTATVILRTPTGEELMDAAIGTGPVDAVYKAINRVVNIPNELIEFSVQSVTAGIDAIG 481
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R + S +A
Sbjct: 482 EVTIRLRAEGRVFSGHA 498
[89][TOP]
>UniRef100_A2BX52 2-isopropylmalate synthase n=1 Tax=Prochlorococcus marinus str. MIT
9515 RepID=LEU1_PROM5
Length = 546
Score = 105 bits (262), Expect = 2e-21
Identities = 56/141 (39%), Positives = 93/141 (65%), Gaps = 2/141 (1%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
E+GY L L++ F RFK +A++K+ +TD DL A+VS++V PE+ ++L +Q++CG+
Sbjct: 360 EMGYDLSREDLNDAFARFKDLADRKREITDRDLEAIVSEQVQLPESRFQLSHVQVSCGST 419
Query: 185 GLSTSTVKLADSD-GKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
T+TV + +++ E + ++GTGPVDA +A++ + K P L+E+S+ +VTEGIDA+
Sbjct: 420 SKPTATVTILNTETHTEDTSVAIGTGPVDAVCEAINELAKVPNELIEFSVKSVTEGIDAL 479
Query: 362 ATTRVLIRGDNN-YSSTNAVT 421
+ IR N YS +A T
Sbjct: 480 GEVTIRIRNKNKIYSGHSADT 500
[90][TOP]
>UniRef100_C7MNU3 2-isopropylmalate synthase n=1 Tax=Cryptobacterium curtum DSM 15641
RepID=C7MNU3_CRYCD
Length = 513
Score = 105 bits (261), Expect = 2e-21
Identities = 55/126 (43%), Positives = 77/126 (61%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY D L L+ RF VA++KK V D DL +LV+D+ +A++ L +Q++CG
Sbjct: 345 LGYTFDPPALDALYERFLEVADRKKEVYDEDLESLVADQARVTDAIYTLEAVQVSCGFPL 404
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
T+T+ L D G C+ GTGP+DAA+KAVD I+ L E+S+NAVT GIDA+
Sbjct: 405 TPTATLTLRDDQGATQTVCAFGTGPIDAAFKAVDEIMNVQGELQEFSVNAVTHGIDALGE 464
Query: 368 TRVLIR 385
V +R
Sbjct: 465 VTVRVR 470
[91][TOP]
>UniRef100_Q112U2 2-isopropylmalate synthase n=1 Tax=Trichodesmium erythraeum IMS101
RepID=LEU1_TRIEI
Length = 541
Score = 105 bits (261), Expect = 2e-21
Identities = 52/137 (37%), Positives = 88/137 (64%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L D +++ F +FK +A++KK +TD DL ++V+ E+ QP +++L +Q++CG
Sbjct: 360 ELGFKLSDEEINKAFIKFKDLADKKKEITDWDLESIVNAEIQQPPELFRLELVQVSCGDR 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV + +G+E ++GTGPVDA YKA++ +V L+E+S+ +VT GIDAI
Sbjct: 420 SRPTATVIIRTPNGEELTDAAIGTGPVDAVYKAINRVVNVENDLVEFSVQSVTAGIDAIG 479
Query: 365 TTRVLIRGDNNYSSTNA 415
+ +R + S +A
Sbjct: 480 EVTIRVRHEGRVYSGHA 496
[92][TOP]
>UniRef100_P94907 2-isopropylmalate synthase n=1 Tax=Microcystis aeruginosa
RepID=LEU1_MICAE
Length = 533
Score = 104 bits (260), Expect = 3e-21
Identities = 56/140 (40%), Positives = 87/140 (62%), Gaps = 1/140 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L + +L+N F +FK +A++KK +TD DL A+V+DE+ ++L +Q++CG
Sbjct: 361 ELGFELSETELNNAFIQFKEMADRKKEITDRDLEAIVNDEIDTVPDHFRLELVQVSCGNN 420
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV + DG E ++GTGPVDA KA+D +V+ P L+ +S+ VTEGIDA+
Sbjct: 421 ARPTATVTIRTPDGSELSDAAIGTGPVDALCKAIDRVVQIPNELISFSVREVTEGIDALG 480
Query: 365 TTRVLIR-GDNNYSSTNAVT 421
+ +R YS+ A T
Sbjct: 481 EVTIRLRYAGRTYSARAADT 500
[93][TOP]
>UniRef100_B2J7L4 2-isopropylmalate synthase n=1 Tax=Nostoc punctiforme PCC 73102
RepID=B2J7L4_NOSP7
Length = 540
Score = 104 bits (259), Expect = 3e-21
Identities = 56/138 (40%), Positives = 86/138 (62%), Gaps = 1/138 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEV-FQPEAVWKLLDMQITCGT 181
ELG+ L++ L+ F RFK VA++KK ++D DL A+V DE Q E+ +++ +Q+ CG
Sbjct: 362 ELGFELNEADLNKAFNRFKDVADKKKEISDWDLEAIVRDETQIQVESGFQIEHVQVICGD 421
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
T+T+ + DGK SVGTGPVDA Y+A++ +V+ P L+E+S+ +VT GIDA+
Sbjct: 422 CTCPTATITIVTPDGKILTDASVGTGPVDAVYQAINRLVQIPNQLIEFSVQSVTGGIDAL 481
Query: 362 ATTRVLIRGDNNYSSTNA 415
T V ++ S A
Sbjct: 482 GTVTVRLKHQERIFSGQA 499
[94][TOP]
>UniRef100_A9WC27 2-isopropylmalate synthase n=2 Tax=Chloroflexus RepID=A9WC27_CHLAA
Length = 568
Score = 104 bits (259), Expect = 3e-21
Identities = 51/127 (40%), Positives = 84/127 (66%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
E GY L++ + ++F RFK + ++KK+V D D+ AL++ E+ ++KL +Q G
Sbjct: 353 EKGYKLNEEEFQHVFARFKDLCDRKKKVDDRDIEALIAGEMQHTPELYKLDHVQYASGIG 412
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
+ T+TV+L DG+ + + GTGPVDA Y+A++ I++ P L+E+S+NA+TEG+DA+A
Sbjct: 413 MIPTATVRLIGPDGQTRIDSAQGTGPVDAVYQAINRIIQRPNELIEFSINAITEGLDAVA 472
Query: 365 TTRVLIR 385
V IR
Sbjct: 473 EVTVRIR 479
[95][TOP]
>UniRef100_A3YY55 2-isopropylmalate synthase n=1 Tax=Synechococcus sp. WH 5701
RepID=A3YY55_9SYNE
Length = 540
Score = 104 bits (259), Expect = 3e-21
Identities = 54/127 (42%), Positives = 82/127 (64%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LGY L+ L F RFK +A++K+ +TD DL A+VSD+ Q EA + L +Q++ GT
Sbjct: 360 DLGYTLERDDLDEAFARFKELADRKREITDRDLEAIVSDQAQQTEARYVLKLVQVSTGTN 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L SDG E ++GTGPVDA +A++ + + P L+E+S+ +VTEGIDA+
Sbjct: 420 LQPTATVTLTTSDGAELTEAAIGTGPVDAVCQALNSLARVPNELVEFSVKSVTEGIDAMG 479
Query: 365 TTRVLIR 385
+ +R
Sbjct: 480 EVTIRLR 486
[96][TOP]
>UniRef100_B9YKB8 2-isopropylmalate synthase n=1 Tax='Nostoc azollae' 0708
RepID=B9YKB8_ANAAZ
Length = 530
Score = 102 bits (255), Expect = 1e-20
Identities = 50/124 (40%), Positives = 82/124 (66%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
EL + L D L+ F RFK VA++KK ++D DL A+V+DE+ Q ++++ +Q++CG+
Sbjct: 360 ELSFELSDKDLNKAFIRFKEVADKKKEISDWDLEAIVNDEIQQAPDLFRVELVQVSCGSN 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L +G+E ++GTGP+DA YKA++ +V P L+E+S+ +VT GIDA+
Sbjct: 420 TQPTATVTLRTPNGEELTDAAIGTGPIDAVYKAINRVVNVPNELIEFSVQSVTGGIDALG 479
Query: 365 TTRV 376
+
Sbjct: 480 EVTI 483
[97][TOP]
>UniRef100_A7NJH6 2-isopropylmalate synthase n=1 Tax=Roseiflexus castenholzii DSM
13941 RepID=A7NJH6_ROSCS
Length = 556
Score = 102 bits (254), Expect = 1e-20
Identities = 54/127 (42%), Positives = 77/127 (60%), Gaps = 1/127 (0%)
Frame = +2
Query: 8 LGYVLD-DGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+GY D + + + +F RFK + ++KK V D DL L + +++L +Q+TCGT
Sbjct: 347 MGYEFDSEEEFNQVFQRFKELCDKKKVVDDRDLEVLATGGSLHTPELYRLEHVQVTCGTG 406
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
+TV++ D DG + GTGPVDA YKA+D IV P L+E+S+ AVTEGIDA+A
Sbjct: 407 VTPVATVRITDPDGNTQTTAAHGTGPVDAIYKAIDKIVGRPNDLIEFSIKAVTEGIDAVA 466
Query: 365 TTRVLIR 385
V IR
Sbjct: 467 EVSVRIR 473
[98][TOP]
>UniRef100_B8HST9 2-isopropylmalate synthase n=1 Tax=Cyanothece sp. PCC 7425
RepID=B8HST9_CYAP4
Length = 541
Score = 102 bits (253), Expect = 2e-20
Identities = 53/138 (38%), Positives = 86/138 (62%), Gaps = 1/138 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDM-QITCGT 181
ELG+ L + L+ F RFK +A++KK ++D DL A+V DE + L++ Q++CG
Sbjct: 363 ELGFELSETDLNKAFVRFKDLADKKKEISDWDLEAIVKDETQSQDVTGFGLELVQVSCGD 422
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
T+TV + +G+E ++GTGPVDA Y+A++ +V P L+E+S+ +VTEGIDAI
Sbjct: 423 HARPTATVTIRTPEGEELTDAAIGTGPVDAVYRAINRVVNVPNQLIEFSVQSVTEGIDAI 482
Query: 362 ATTRVLIRGDNNYSSTNA 415
+ +R ++ S +A
Sbjct: 483 GEVTIRLRHEDRIYSGHA 500
[99][TOP]
>UniRef100_A5G7V0 2-isopropylmalate synthase n=1 Tax=Geobacter uraniireducens Rf4
RepID=A5G7V0_GEOUR
Length = 516
Score = 100 bits (250), Expect = 4e-20
Identities = 53/118 (44%), Positives = 78/118 (66%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY LDD +L+ F RFKA+A+ KK V D DL A+V+DEV E +KL + +TCG+
Sbjct: 350 ELGYDLDDEKLNRAFDRFKALADLKKEVFDEDLDAIVADEVLTAEEKYKLSHITVTCGSF 409
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDA 358
++T+TV++ + DG + +G GPVDA KA+ + K A LL+Y++ ++T G DA
Sbjct: 410 AVATATVQM-EIDGIQVRTAELGDGPVDATLKAIKKLTKTKAKLLQYNVGSITGGTDA 466
[100][TOP]
>UniRef100_B5EHU7 2-isopropylmalate synthase n=1 Tax=Geobacter bemidjiensis Bem
RepID=B5EHU7_GEOBB
Length = 515
Score = 100 bits (249), Expect = 5e-20
Identities = 55/126 (43%), Positives = 78/126 (61%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ LDD L+ F RFKA+A+ KK V D DL A+V DE E +KL + +TCG+
Sbjct: 348 ELGHELDDEALNKAFTRFKALADLKKEVFDEDLDAIVLDEAKNIEEKYKLSHITVTCGSF 407
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
++T+TV++ + DG + A +G GPVDA KA+ + K LL+Y++ A+T G DAI
Sbjct: 408 AVATATVQM-EIDGMQVRAAELGDGPVDATMKAIKKLTKRDVKLLQYNVGAITGGTDAIG 466
Query: 365 TTRVLI 382
V I
Sbjct: 467 EVTVRI 472
[101][TOP]
>UniRef100_C7DAW2 2-isopropylmalate synthase n=1 Tax=Thalassiobium sp. R2A62
RepID=C7DAW2_9RHOB
Length = 519
Score = 100 bits (249), Expect = 5e-20
Identities = 59/135 (43%), Positives = 81/135 (60%)
Frame = +2
Query: 2 NELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGT 181
+ELG+ L D QL ++F RFK +A++KK V D DLIAL+ EA+ KL M++ CGT
Sbjct: 342 SELGFDLSDNQLKDVFVRFKDLADRKKEVFDDDLIALMGASEPADEAI-KLKSMRVVCGT 400
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
G +++ L + +G EH G GPVDAA+ AV +V A L Y ++AVTEG DA
Sbjct: 401 EGPQEASMTL-EVNGTEHTTTETGDGPVDAAFNAVKALVNHEARLQLYQVSAVTEGTDAQ 459
Query: 362 ATTRVLIRGDNNYSS 406
AT V + D S+
Sbjct: 460 ATVSVRLEEDGKIST 474
[102][TOP]
>UniRef100_C6ML81 2-isopropylmalate synthase n=1 Tax=Geobacter sp. M18
RepID=C6ML81_9DELT
Length = 515
Score = 100 bits (249), Expect = 5e-20
Identities = 54/132 (40%), Positives = 84/132 (63%), Gaps = 1/132 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ LD+ L+N F RFKA+A+ KK V D DL A+V+D+ + + +KL + +TCG+
Sbjct: 348 ELGHELDEAGLNNAFTRFKALADLKKEVYDEDLDAIVADQTKKIDEKYKLSHITVTCGSF 407
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
++T+TV++ + DG + +G GPVDA KA+ + K A LL+Y++ ++T G DA+
Sbjct: 408 AVATATVQM-EIDGIQVRTAELGDGPVDATLKAIKKLAKRDAQLLQYNVGSITGGTDALG 466
Query: 365 TTRVLI-RGDNN 397
V I GD N
Sbjct: 467 EVTVRITEGDRN 478
[103][TOP]
>UniRef100_B5ING5 2-isopropylmalate synthase n=1 Tax=Cyanobium sp. PCC 7001
RepID=B5ING5_9CHRO
Length = 547
Score = 100 bits (248), Expect = 6e-20
Identities = 54/128 (42%), Positives = 83/128 (64%), Gaps = 1/128 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQP-EAVWKLLDMQITCGT 181
ELGY L L + F RFK +A++K+ +TD DL A+VS++V Q E + L +Q++CGT
Sbjct: 360 ELGYELSREDLDDAFARFKELADRKREITDRDLEAIVSEQVQQTDEGRFTLKSVQVSCGT 419
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
T+TV L +DG E ++GTGPVDA +A++ + + P L+E+S+ +VTEGIDA+
Sbjct: 420 GLQPTATVTLLTADGAEISEAAIGTGPVDAVCQALNRLAQVPNELVEFSVKSVTEGIDAM 479
Query: 362 ATTRVLIR 385
+ +R
Sbjct: 480 GEVTIRLR 487
[104][TOP]
>UniRef100_Q74BX2 2-isopropylmalate synthase n=1 Tax=Geobacter sulfurreducens
RepID=Q74BX2_GEOSL
Length = 512
Score = 99.4 bits (246), Expect = 1e-19
Identities = 54/130 (41%), Positives = 80/130 (61%), Gaps = 1/130 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L D L+ F RFKA+A+ KK V D DL A+V+DEV +P ++L + +TCG+
Sbjct: 346 ELGYELSDEDLNKAFERFKALADMKKEVFDEDLDAIVADEVMRPSEKYRLAHITVTCGSF 405
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
++T+TV++ + DG +G GPVDA KA+ + K A L +Y++ ++T G DA
Sbjct: 406 AVATATVQM-EIDGVAVRTAELGDGPVDATLKAIKKLTKTKARLQQYNVGSITGGTDAQG 464
Query: 365 TTRV-LIRGD 391
V L+ GD
Sbjct: 465 EVTVRLVDGD 474
[105][TOP]
>UniRef100_Q39W73 2-isopropylmalate synthase n=1 Tax=Geobacter metallireducens GS-15
RepID=Q39W73_GEOMG
Length = 512
Score = 99.4 bits (246), Expect = 1e-19
Identities = 54/130 (41%), Positives = 78/130 (60%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L D L+ F RFKA+A+ KK V D DL ALV+DEV +P ++L + +TCG+
Sbjct: 346 ELGYELSDEDLNRAFERFKALADLKKEVFDEDLDALVADEVMRPAEKFRLSHITVTCGSF 405
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
++TSTV++ + DG +G GPVDA KA+ + K A L +Y++ ++T G DA
Sbjct: 406 AVATSTVQM-EIDGTAVRTAELGDGPVDATLKAIKKLTKTKAKLQQYNVGSITGGTDAQG 464
Query: 365 TTRVLIRGDN 394
V + N
Sbjct: 465 EVTVRVTDGN 474
[106][TOP]
>UniRef100_D0CPN4 2-isopropylmalate synthase n=1 Tax=Silicibacter lacuscaerulensis
ITI-1157 RepID=D0CPN4_9RHOB
Length = 526
Score = 99.4 bits (246), Expect = 1e-19
Identities = 58/128 (45%), Positives = 83/128 (64%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY + D QL ++F RFK +A++KK V D DLIAL+S + + + +L+ M++TCGT G
Sbjct: 351 LGYEVGDNQLKDIFVRFKELADRKKEVFDDDLIALMSADDATNDHL-QLVSMKVTCGTGG 409
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
+ +TV+L + DGK+ +A G GPVDA +KA+ I A L Y ++AVTEG DA AT
Sbjct: 410 QAEATVEL-EVDGKDVIATEHGDGPVDATFKAIRAIYPNKAHLQLYQVHAVTEGTDAQAT 468
Query: 368 TRVLIRGD 391
V + D
Sbjct: 469 VSVRLEED 476
[107][TOP]
>UniRef100_C6E526 2-isopropylmalate synthase n=1 Tax=Geobacter sp. M21
RepID=C6E526_GEOSM
Length = 515
Score = 99.0 bits (245), Expect = 1e-19
Identities = 54/126 (42%), Positives = 78/126 (61%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ LD+ L+ F RFKA+A+ KK V D DL A+V DE E +KL + +TCG+
Sbjct: 348 ELGHELDEEALNKAFTRFKALADLKKEVFDEDLDAIVLDEAKNIEEKYKLSHITVTCGSF 407
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
++T+TV++ + DG + A +G GPVDA KA+ + K LL+Y++ A+T G DAI
Sbjct: 408 AVATATVQM-EIDGMQVRAAELGDGPVDATMKAIKKLAKRDVKLLQYNVGAITGGTDAIG 466
Query: 365 TTRVLI 382
V I
Sbjct: 467 EVTVRI 472
[108][TOP]
>UniRef100_B9M5A8 2-isopropylmalate synthase n=1 Tax=Geobacter sp. FRC-32
RepID=B9M5A8_GEOSF
Length = 516
Score = 99.0 bits (245), Expect = 1e-19
Identities = 51/118 (43%), Positives = 77/118 (65%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY LDD +L+ F RFKA+A+ KK V D DL ALV+DE+ + V+KL + +TCG+
Sbjct: 350 ELGYDLDDEKLNQAFERFKALADLKKEVFDEDLDALVADEIMRAHEVYKLSHITVTCGSF 409
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDA 358
++T+TV++ + +G +G GPVDA KA+ + K A L +Y++ ++T G DA
Sbjct: 410 AVATATVQM-EIEGNPVRTAELGDGPVDATLKAIKKLTKTKAKLQQYNVGSITGGTDA 466
[109][TOP]
>UniRef100_B9NRA6 2-isopropylmalate synthase n=1 Tax=Rhodobacteraceae bacterium KLH11
RepID=B9NRA6_9RHOB
Length = 522
Score = 97.4 bits (241), Expect = 4e-19
Identities = 56/128 (43%), Positives = 83/128 (64%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY + D QL ++F RFK +A++KK V D DLIAL++ + + + +L+ M++TCGT G
Sbjct: 348 LGYEVGDNQLKDIFVRFKDLADRKKEVFDDDLIALMTLD--EADDYLQLVSMKVTCGTGG 405
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
+ STV+L + DG++ +A G GPVDA ++A+ I A L Y ++AVTEG DA AT
Sbjct: 406 QAESTVEL-EMDGEDVIATEHGDGPVDATFRAIRAIYPNKAHLQLYQVHAVTEGTDAQAT 464
Query: 368 TRVLIRGD 391
V + D
Sbjct: 465 VSVRLEED 472
[110][TOP]
>UniRef100_Q8DJ32 2-isopropylmalate synthase n=1 Tax=Thermosynechococcus elongatus
BP-1 RepID=LEU1_THEEB
Length = 535
Score = 97.4 bits (241), Expect = 4e-19
Identities = 52/138 (37%), Positives = 85/138 (61%), Gaps = 1/138 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV-WKLLDMQITCGT 181
ELG+ L + +L+ F RFK +A++KK +TD DL A+ DE + ++L +Q++CG
Sbjct: 365 ELGFELSETELNKAFLRFKDLADKKKEITDWDLEAIAKDETQGIDLQGYQLEFVQVSCGD 424
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
T+TV + G+E ++GTGPVDA Y+A++ +V+ P L+EYS+ +VT GIDAI
Sbjct: 425 HARPTATVTVRTPSGEELTDAAIGTGPVDAVYRAINRVVQIPNRLIEYSVQSVTAGIDAI 484
Query: 362 ATTRVLIRGDNNYSSTNA 415
+ ++ + S +A
Sbjct: 485 GEVTIRLQHQDRIYSGHA 502
[111][TOP]
>UniRef100_Q3J3Z9 2-isopropylmalate synthase n=1 Tax=Rhodobacter sphaeroides 2.4.1
RepID=Q3J3Z9_RHOS4
Length = 529
Score = 96.7 bits (239), Expect = 7e-19
Identities = 56/138 (40%), Positives = 84/138 (60%), Gaps = 1/138 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEA-VWKLLDMQITCGT 181
+LGY L D QL+++F RFKA+A++KK V D D++AL+ D+V E +L +++ CGT
Sbjct: 351 DLGYDLADNQLNDVFVRFKALADRKKEVYDDDIVALIQDQVTSAEHDTLQLKRLRVVCGT 410
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
G + + L+ +G +H + G GPVDAA+ AV +I A L Y ++AVTEG DA
Sbjct: 411 DGPQEAEMTLS-VEGVDHAIDATGDGPVDAAFNAVKMIYPHHAKLHLYQVHAVTEGTDAQ 469
Query: 362 ATTRVLIRGDNNYSSTNA 415
AT V + D ++ A
Sbjct: 470 ATVSVRLEEDGKIATGQA 487
[112][TOP]
>UniRef100_A3PIF0 2-isopropylmalate synthase n=2 Tax=Rhodobacter sphaeroides
RepID=A3PIF0_RHOS1
Length = 529
Score = 96.7 bits (239), Expect = 7e-19
Identities = 56/138 (40%), Positives = 84/138 (60%), Gaps = 1/138 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEA-VWKLLDMQITCGT 181
+LGY L D QL+++F RFKA+A++KK V D D++AL+ D+V E +L +++ CGT
Sbjct: 351 DLGYDLADNQLNDVFVRFKALADRKKEVYDDDIVALIQDQVTSAEHDTLQLKRLRVVCGT 410
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
G + + L+ +G +H + G GPVDAA+ AV +I A L Y ++AVTEG DA
Sbjct: 411 DGPQEAEMTLS-VEGVDHAIDATGDGPVDAAFNAVKMIYPHHAKLHLYQVHAVTEGTDAQ 469
Query: 362 ATTRVLIRGDNNYSSTNA 415
AT V + D ++ A
Sbjct: 470 ATVSVRLEEDGKIATGQA 487
[113][TOP]
>UniRef100_B6B711 2-isopropylmalate synthase n=1 Tax=Rhodobacterales bacterium Y4I
RepID=B6B711_9RHOB
Length = 528
Score = 96.7 bits (239), Expect = 7e-19
Identities = 55/133 (41%), Positives = 80/133 (60%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY + D QL ++F RFK +A++KK V D DLIAL+ K++ M++ CGT G
Sbjct: 352 LGYEVGDNQLKDVFVRFKELADRKKEVFDDDLIALMRTGTDAENDHLKIVSMKVVCGTGG 411
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
+ +TV++ + DGK+ + G GPVDA +KA+ I A L Y ++AVTEG DA AT
Sbjct: 412 PAEATVEM-EIDGKDVTETAEGDGPVDATFKAIRKIYPNTARLQLYQVHAVTEGTDAQAT 470
Query: 368 TRVLIRGDNNYSS 406
V + D N ++
Sbjct: 471 VSVRLEEDGNIAT 483
[114][TOP]
>UniRef100_B1X5H2 2-isopropylmalate synthase n=1 Tax=Paulinella chromatophora
RepID=B1X5H2_PAUCH
Length = 548
Score = 96.7 bits (239), Expect = 7e-19
Identities = 48/127 (37%), Positives = 78/127 (61%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L+ +L F FK +A+ K+ VTD D+ ++S+ + QPE V+KL +Q++CG+
Sbjct: 360 ELGYHLNPEELDECFTLFKELADGKRNVTDQDIELIISEHIQQPEEVYKLKLVQVSCGST 419
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV + +D E ++GTGP+DA Y+ ++ IV P L E+S+ +VT GI+
Sbjct: 420 LCPTATVTVQKNDNTEITKAAIGTGPIDAVYRTLNEIVGMPNELTEFSVKSVTAGINGKG 479
Query: 365 TTRVLIR 385
+ +R
Sbjct: 480 EVTIRLR 486
[115][TOP]
>UniRef100_B0CEB7 2-isopropylmalate synthase n=1 Tax=Acaryochloris marina MBIC11017
RepID=B0CEB7_ACAM1
Length = 546
Score = 95.5 bits (236), Expect = 2e-18
Identities = 55/133 (41%), Positives = 83/133 (62%), Gaps = 2/133 (1%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV--WKLLDMQITCG 178
ELG L + L+ F RFK +A++KK ++D DL A+V DE Q + + ++L +Q++CG
Sbjct: 364 ELGMELSEQDLNKAFIRFKELADKKKEISDRDLEAIVKDET-QSQVIGGFRLELVQVSCG 422
Query: 179 TLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDA 358
T+TV + +E +VGTGPVDA Y+A++ +VK P L+E+S+ +VT GIDA
Sbjct: 423 DHACPTATVTICTPGNQELTDAAVGTGPVDAVYQAINRVVKVPNRLIEFSVQSVTAGIDA 482
Query: 359 IATTRVLIRGDNN 397
I V IR + N
Sbjct: 483 IG--EVTIRLEQN 493
[116][TOP]
>UniRef100_Q0FCE5 2-isopropylmalate synthase n=1 Tax=Rhodobacterales bacterium
HTCC2255 RepID=Q0FCE5_9RHOB
Length = 510
Score = 95.5 bits (236), Expect = 2e-18
Identities = 57/125 (45%), Positives = 78/125 (62%), Gaps = 1/125 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSD-EVFQPEAVWKLLDMQITCGT 181
+LGY L D QL ++F RFKA+A++KK V D DL+ALVSD E ++ +Q+TCGT
Sbjct: 344 DLGYDLGDNQLKDVFVRFKALADRKKEVYDDDLLALVSDEETNSANDTIQVKSLQVTCGT 403
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
G T+++ L D E+ ++G GPVDA +KAV + A L Y ++AVTEG DA
Sbjct: 404 EGPQTASLALI-IDKVEYSHKAIGDGPVDAVFKAVQALFPHQAHLQLYQVHAVTEGTDAQ 462
Query: 362 ATTRV 376
AT V
Sbjct: 463 ATVSV 467
[117][TOP]
>UniRef100_A6TTR8 2-isopropylmalate synthase n=1 Tax=Alkaliphilus metalliredigens
QYMF RepID=A6TTR8_ALKMQ
Length = 513
Score = 95.1 bits (235), Expect = 2e-18
Identities = 54/130 (41%), Positives = 80/130 (61%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY + +L+ +F FK +A++KK + D DL ALV D+ E +++L + I CG +
Sbjct: 345 ELGYEISKEKLNEVFKEFKILADRKKVIYDRDLEALVQDQKQNFEEIYQLKEFVINCGNI 404
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
ST+ +KL DGKE + G GP+DAA+KA+D IV L +YS+ +VTEG DA+
Sbjct: 405 ITSTANIKLI-KDGKELEEVAKGFGPIDAAFKAIDNIVGGDFKLEDYSVESVTEGEDALG 463
Query: 365 TTRVLIRGDN 394
V I+ +N
Sbjct: 464 EAVVKIKRNN 473
[118][TOP]
>UniRef100_A8CP47 2-isopropylmalate synthase n=1 Tax=Dehalococcoides sp. VS
RepID=A8CP47_9CHLR
Length = 505
Score = 95.1 bits (235), Expect = 2e-18
Identities = 50/129 (38%), Positives = 79/129 (61%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L++ F FK +A++KK VTD D+ ALV++E+ ++ L +Q+T G
Sbjct: 342 ELGFDLNEEDFDRAFKAFKDLADKKKDVTDRDIEALVAEELRTTVELYHLDRIQVTSGDR 401
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G+ T+ V+L +G+ ++G+GPVDA YKA++ IV P L E+S+ +VT GIDA+
Sbjct: 402 GIPTAAVRLTTPNGEAAEDAALGSGPVDAVYKAINRIVNVPNKLTEFSVKSVTAGIDALG 461
Query: 365 TTRVLIRGD 391
+ I D
Sbjct: 462 EVLIRIESD 470
[119][TOP]
>UniRef100_UPI0001695207 2-isopropylmalate synthase n=1 Tax=Paenibacillus larvae subsp.
larvae BRL-230010 RepID=UPI0001695207
Length = 515
Score = 94.7 bits (234), Expect = 3e-18
Identities = 45/127 (35%), Positives = 79/127 (62%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LGYVL++ QL+ F +FK +A++KK V D D+ A++ +++ Q V+ L MQ++ G
Sbjct: 342 DLGYVLNEDQLNTAFAKFKKLADKKKNVLDEDIRAIIDEKLIQVPEVFVLDTMQVSYGNQ 401
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
+ T+TV++ DG +VG G VDA Y A+D +E L +Y +++V++G DA+
Sbjct: 402 SVPTATVRILTQDGGRLEEAAVGNGSVDAIYNAIDKATREEVELADYKIHSVSQGQDALG 461
Query: 365 TTRVLIR 385
V+++
Sbjct: 462 EVHVMLK 468
[120][TOP]
>UniRef100_A5FR43 2-isopropylmalate synthase n=2 Tax=Dehalococcoides
RepID=A5FR43_DEHSB
Length = 505
Score = 94.7 bits (234), Expect = 3e-18
Identities = 51/129 (39%), Positives = 78/129 (60%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L++ F FK +A++KK VTD D+ ALV++E+ ++ L +Q+T G
Sbjct: 342 ELGFDLNEEDFDRAFKAFKDLADKKKDVTDRDIEALVAEELRTTVELYHLDRIQVTSGDR 401
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G+ T+ V+L +G S+G+GPVDA YKA++ IV P L E+S+ +VT GIDA+
Sbjct: 402 GIPTAAVRLTTPNGGAVEDASLGSGPVDAVYKAINRIVNVPNKLTEFSVKSVTAGIDALG 461
Query: 365 TTRVLIRGD 391
+ I D
Sbjct: 462 EVLIRIESD 470
[121][TOP]
>UniRef100_C9RAW9 2-isopropylmalate synthase n=1 Tax=Ammonifex degensii KC4
RepID=C9RAW9_9THEO
Length = 525
Score = 94.7 bits (234), Expect = 3e-18
Identities = 55/127 (43%), Positives = 76/127 (59%), Gaps = 1/127 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L + +L+ F RFK + ++KK +TD DL+ALV +E+ Q ++L I+ GT
Sbjct: 352 ELGYELSEEELNAAFQRFKELCDRKKEITDDDLLALVEEEIGQVPPTYELRYFHISSGTT 411
Query: 185 GLSTSTVKL-ADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
+ T+TV L + KE AC G GPVDA YKA+D + L YS+ AVTEG DAI
Sbjct: 412 VVPTATVALKIGEEVKEEAAC--GNGPVDAIYKAIDKLTGRHLRLDSYSIEAVTEGKDAI 469
Query: 362 ATTRVLI 382
+ V +
Sbjct: 470 GSVTVRV 476
[122][TOP]
>UniRef100_C9CV77 2-isopropylmalate synthase n=1 Tax=Silicibacter sp. TrichCH4B
RepID=C9CV77_9RHOB
Length = 527
Score = 94.7 bits (234), Expect = 3e-18
Identities = 56/128 (43%), Positives = 80/128 (62%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY + D QL +LF RFK +A++KK V D D+IAL+ + + + KL+ M++ CGT G
Sbjct: 352 LGYEIGDNQLKDLFVRFKELADRKKEVFDDDIIALMRTSGDEDDHL-KLVSMKVVCGTGG 410
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
+ STV++ + DGK+ + G GPVDA +KA+ I A L Y ++AVTEG DA AT
Sbjct: 411 PAESTVEM-EVDGKDVTETAEGDGPVDATFKAIRKIHPNAAHLQLYQVHAVTEGTDAQAT 469
Query: 368 TRVLIRGD 391
V + D
Sbjct: 470 VSVRLEED 477
[123][TOP]
>UniRef100_C6QKF2 2-isopropylmalate synthase n=1 Tax=Geobacillus sp. Y4.1MC1
RepID=C6QKF2_9BACI
Length = 515
Score = 94.4 bits (233), Expect = 4e-18
Identities = 50/128 (39%), Positives = 78/128 (60%), Gaps = 1/128 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQP-EAVWKLLDMQITCGT 181
ELGY L D +++ LF RFK +A++KK +TD DL+AL+ +E F + ++L +Q+ GT
Sbjct: 342 ELGYKLSDEEINKLFVRFKELADKKKDITDDDLVALIFEEKFDHFKDFYQLTSLQVQYGT 401
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
+ T+ V L D +G E + G G V+A Y ++ K P TLL+Y + +V+ G DA+
Sbjct: 402 NQIPTAVVVLKDGEGNEIQEAATGAGSVEALYNTLERCFKTPVTLLDYRIESVSGGRDAL 461
Query: 362 ATTRVLIR 385
A V +R
Sbjct: 462 AQVFVKVR 469
[124][TOP]
>UniRef100_B0TCR1 2-isopropylmalate synthase n=1 Tax=Heliobacterium modesticaldum
Ice1 RepID=LEU1_HELMI
Length = 512
Score = 94.4 bits (233), Expect = 4e-18
Identities = 54/139 (38%), Positives = 82/139 (58%), Gaps = 1/139 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY LDD +L+ F RFKA+A++K+ +TD DL+ LV DE+ + L + IT GT+
Sbjct: 343 ELGYSLDDEKLTKAFARFKALADRKREITDEDLVVLVEDELRAFPEAYSLEYLHITSGTV 402
Query: 185 GLSTSTVKL-ADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
+ T+TV+L + + E +C G GPVDAAYKA++ I A L Y+++A T G D+
Sbjct: 403 LVPTATVRLRREEENFEEASC--GDGPVDAAYKAIEKITGTGARLASYAISATTAGEDSQ 460
Query: 362 ATTRVLIRGDNNYSSTNAV 418
V + + + + V
Sbjct: 461 GEVSVKLEREGRFYTGRGV 479
[125][TOP]
>UniRef100_Q3Z892 2-isopropylmalate synthase n=1 Tax=Dehalococcoides ethenogenes 195
RepID=Q3Z892_DEHE1
Length = 505
Score = 94.0 bits (232), Expect = 5e-18
Identities = 50/129 (38%), Positives = 78/129 (60%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L++ F FK +A++KK VTD D+ ALV++E+ ++ L +Q+T G
Sbjct: 342 ELGFDLNEEDFDRAFKAFKDLADKKKDVTDRDIEALVAEELRTTVELYHLDRIQVTSGDR 401
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G+ T+ V+L +G ++G+GPVDA YKA++ IV P L E+S+ +VT GIDA+
Sbjct: 402 GIPTAAVRLTTPNGGAAEDAALGSGPVDAVYKAINRIVNVPNKLTEFSVKSVTAGIDALG 461
Query: 365 TTRVLIRGD 391
+ I D
Sbjct: 462 EVLIRIESD 470
[126][TOP]
>UniRef100_Q28L52 2-isopropylmalate synthase n=1 Tax=Jannaschia sp. CCS1
RepID=Q28L52_JANSC
Length = 519
Score = 94.0 bits (232), Expect = 5e-18
Identities = 55/128 (42%), Positives = 81/128 (63%), Gaps = 2/128 (1%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LGY + D QL++LF RFKA+A++KK V D DLIALV+D E ++ +++ CGT
Sbjct: 344 DLGYDMADNQLNDLFVRFKALADRKKEVFDDDLIALVTDAGSDGEGHLEVKFLRVICGTE 403
Query: 185 GLSTS--TVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDA 358
++ T+++ D+D H A + G GPVDAA+ AV + A L Y ++AVTEG+DA
Sbjct: 404 APQSADLTLRVGDTD---HQATAQGDGPVDAAFNAVKAVFPNEAALQLYQVSAVTEGMDA 460
Query: 359 IATTRVLI 382
AT V +
Sbjct: 461 QATVTVRV 468
[127][TOP]
>UniRef100_A4WSX7 2-isopropylmalate synthase n=1 Tax=Rhodobacter sphaeroides ATCC
17025 RepID=A4WSX7_RHOS5
Length = 529
Score = 94.0 bits (232), Expect = 5e-18
Identities = 54/138 (39%), Positives = 84/138 (60%), Gaps = 1/138 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEA-VWKLLDMQITCGT 181
+LGY L + QL+++F RFKA+A++KK V D D++AL+ D+ E V +L +++ CGT
Sbjct: 351 DLGYDLGENQLNDVFVRFKALADRKKEVFDDDIVALIQDQATSAEHDVLQLKRLRVVCGT 410
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
G + + L+ +G +H + G GPVDAA+ AV ++ A L Y ++AVTEG DA
Sbjct: 411 DGPQEAEMTLS-VEGVDHSIDATGDGPVDAAFNAVKMLYPHHARLHLYQVHAVTEGTDAQ 469
Query: 362 ATTRVLIRGDNNYSSTNA 415
AT V + D ++ A
Sbjct: 470 ATVSVRLEEDGKIATGQA 487
[128][TOP]
>UniRef100_B7RGZ1 2-isopropylmalate synthase n=1 Tax=Roseobacter sp. GAI101
RepID=B7RGZ1_9RHOB
Length = 523
Score = 93.2 bits (230), Expect = 8e-18
Identities = 54/128 (42%), Positives = 71/128 (55%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY L D QL ++F RFK +A++KK + D DLIAL+ KL M + CGT G
Sbjct: 348 LGYELGDNQLKDVFVRFKELADRKKEIYDEDLIALMRTATDPESDRIKLKSMHVVCGTEG 407
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
+ + + L DG EH G GPVDA++ + +V A L Y +NAVTEG DA AT
Sbjct: 408 PNVAKMTLI-VDGAEHSTEQTGDGPVDASFNCIKALVDHSARLQLYQVNAVTEGTDAQAT 466
Query: 368 TRVLIRGD 391
V + D
Sbjct: 467 VSVRLEED 474
[129][TOP]
>UniRef100_A4J181 2-isopropylmalate synthase n=1 Tax=Desulfotomaculum reducens MI-1
RepID=LEU1_DESRM
Length = 505
Score = 93.2 bits (230), Expect = 8e-18
Identities = 56/128 (43%), Positives = 77/128 (60%), Gaps = 1/128 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L++ +L+ F RFK +A++KK +TD DL A+V DE+ + L + I+ GT
Sbjct: 343 ELGYHLNEEELNLAFSRFKVLADKKKEITDHDLQAMVEDEIKHIPDTYVLKYLHISTGTA 402
Query: 185 GLSTSTVKLADSDG-KEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
+ T+T+ L D KE AC G GPVDA YK VD I TL+ Y++NA+T G DA+
Sbjct: 403 VVPTATLGLQMGDELKEEAAC--GDGPVDAIYKTVDKITGISCTLVNYAINAITGGKDAL 460
Query: 362 ATTRVLIR 385
V IR
Sbjct: 461 GDVTVKIR 468
[130][TOP]
>UniRef100_A4EQL7 2-isopropylmalate synthase n=1 Tax=Roseobacter sp. SK209-2-6
RepID=A4EQL7_9RHOB
Length = 524
Score = 92.8 bits (229), Expect = 1e-17
Identities = 54/128 (42%), Positives = 78/128 (60%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LG+ + D QL ++F RFK +A++KK V D DLIAL+ +++ M++ CGT G
Sbjct: 348 LGFEVGDNQLKDVFVRFKELADRKKEVFDDDLIALMRSGEDAENDYLQIVSMKVVCGTGG 407
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
+ ST+++ + DGK+ A S G GPVDA +KA+ I A L Y ++AVTEG DA AT
Sbjct: 408 PAESTLEM-EVDGKDVSATSEGDGPVDATFKAIRKIHPNTARLQLYQVHAVTEGTDAQAT 466
Query: 368 TRVLIRGD 391
V + D
Sbjct: 467 VSVRLEED 474
[131][TOP]
>UniRef100_B9DMJ6 2-isopropylmalate synthase n=1 Tax=Staphylococcus carnosus subsp.
carnosus TM300 RepID=LEU1_STACT
Length = 510
Score = 92.8 bits (229), Expect = 1e-17
Identities = 50/129 (38%), Positives = 79/129 (61%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LGY + + LF +FK++A++KK V+D D+ ALV + A +++ +Q+ +
Sbjct: 342 QLGYDITAEKQVELFKQFKSIADKKKNVSDHDVHALVQGHSHETNAAYQVETLQLQFVSE 401
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G+ ++ V L D +GKE+ + ++GTG + A Y AVD I K P+ LL Y + +VTEG DA A
Sbjct: 402 GVQSAVVVLKDHEGKEYPSAAIGTGSIVAVYNAVDQIFKAPSELLNYQITSVTEGSDAQA 461
Query: 365 TTRVLIRGD 391
V IR D
Sbjct: 462 QVNVEIRID 470
[132][TOP]
>UniRef100_Q1GEA2 2-isopropylmalate synthase n=1 Tax=Ruegeria sp. TM1040
RepID=Q1GEA2_SILST
Length = 527
Score = 92.4 bits (228), Expect = 1e-17
Identities = 54/130 (41%), Positives = 81/130 (62%)
Frame = +2
Query: 2 NELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGT 181
+ LG+ + D QL ++F RFK +A++KK V D D+IAL+ + + + KL+ M++ CGT
Sbjct: 350 SSLGFEIGDNQLKDVFVRFKELADRKKEVFDDDIIALMRTSGDEDDHL-KLVSMKVVCGT 408
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
G + STV++ + DGK+ + G GPVDA +KA+ I A L Y ++AVTEG DA
Sbjct: 409 GGPAESTVEM-EVDGKDVTETAEGDGPVDATFKAIRKIHPNAAHLQLYQVHAVTEGTDAQ 467
Query: 362 ATTRVLIRGD 391
AT V + D
Sbjct: 468 ATVSVRLEED 477
[133][TOP]
>UniRef100_B7QYF0 2-isopropylmalate synthase n=1 Tax=Ruegeria sp. R11
RepID=B7QYF0_9RHOB
Length = 523
Score = 92.4 bits (228), Expect = 1e-17
Identities = 54/130 (41%), Positives = 81/130 (62%)
Frame = +2
Query: 2 NELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGT 181
++LG+ + D QL +LF RFK +A++KK V D D+IAL+ + + KL+ M++ CGT
Sbjct: 346 SQLGFEVGDNQLKDLFVRFKELADRKKEVFDDDIIALMRTGGDDDDHL-KLVSMKVVCGT 404
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
G + ST+++ + DGK+ + G GPVDA +KA+ I A L Y ++AVTEG DA
Sbjct: 405 GGPAESTIEM-EVDGKDVTEAAEGDGPVDATFKAIRKIHPNAAHLQLYQVHAVTEGTDAQ 463
Query: 362 ATTRVLIRGD 391
AT V + D
Sbjct: 464 ATVSVRLEED 473
[134][TOP]
>UniRef100_A3JMT2 2-isopropylmalate synthase n=1 Tax=Rhodobacterales bacterium
HTCC2150 RepID=A3JMT2_9RHOB
Length = 524
Score = 92.4 bits (228), Expect = 1e-17
Identities = 55/130 (42%), Positives = 77/130 (59%), Gaps = 1/130 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLL-DMQITCGT 181
ELG+ L D QL ++F RFK +A++KK + DLIAL+ DE E ++ +Q+ CGT
Sbjct: 347 ELGFELGDNQLKDVFVRFKELADRKKEIFSDDLIALMRDEAATGEGNHLVIKSLQVVCGT 406
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
G T+ + + D DG E A + G GPVDA++ AV + A L Y ++AVTEG DA
Sbjct: 407 SGPQTADLVM-DVDGVEKSAHATGDGPVDASFNAVKALFPHSARLQLYQVSAVTEGTDAQ 465
Query: 362 ATTRVLIRGD 391
AT V + D
Sbjct: 466 ATVTVRMEED 475
[135][TOP]
>UniRef100_Q5LWC0 2-isopropylmalate synthase n=1 Tax=Ruegeria pomeroyi
RepID=Q5LWC0_SILPO
Length = 524
Score = 92.0 bits (227), Expect = 2e-17
Identities = 53/128 (41%), Positives = 80/128 (62%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY + D QL ++F RFK +A++KK V D D+IAL+ + +L+ M++ CGT G
Sbjct: 348 LGYEVGDNQLKDIFVRFKELADRKKEVFDDDVIALMRSGENAEQDHLQLVSMKVICGTGG 407
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
+ +TV++ + DGK+ A + G GPVDA++KA+ + A L Y ++AVTEG DA AT
Sbjct: 408 PAEATVEM-EIDGKDVSATAHGDGPVDASFKAIRALHPNEAHLQLYQVHAVTEGTDAQAT 466
Query: 368 TRVLIRGD 391
V + D
Sbjct: 467 VSVRLEED 474
[136][TOP]
>UniRef100_A1AL90 2-isopropylmalate synthase n=1 Tax=Pelobacter propionicus DSM 2379
RepID=A1AL90_PELPD
Length = 518
Score = 92.0 bits (227), Expect = 2e-17
Identities = 51/131 (38%), Positives = 84/131 (64%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ LDD L+ F RFKA+A+ KK V D DL A+V+DE + E ++KL+ + ++CG+L
Sbjct: 353 ELGHELDDEMLNRAFVRFKALADLKKEVFDEDLDAIVADE-SREEEMYKLVLLNVSCGSL 411
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
++T+TVK+ + +G+ A +G GPVDA KA+ + K A L ++++ ++T G DA
Sbjct: 412 SVATATVKM-EINGQLLRAAELGDGPVDATLKAIRKLTKSKAKLEQFNVGSITGGTDAQG 470
Query: 365 TTRVLIRGDNN 397
+ + N+
Sbjct: 471 EVTMRVSDGNH 481
[137][TOP]
>UniRef100_B3EBJ2 2-isopropylmalate synthase n=1 Tax=Geobacter lovleyi SZ
RepID=B3EBJ2_GEOLS
Length = 519
Score = 91.7 bits (226), Expect = 2e-17
Identities = 50/118 (42%), Positives = 78/118 (66%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ LDD L+ F RFKA+A+ KK V D DL A+V+DE + E +KL + +TCG+
Sbjct: 354 ELGHDLDDEMLNRAFERFKALADLKKEVFDEDLDAIVTDE-SREEDQYKLEHITVTCGSF 412
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDA 358
++T+TV++ + +GK +G GPVD+A+KA+ + K A L +Y++ ++T G DA
Sbjct: 413 AVATATVQM-EINGKPVRTAELGDGPVDSAFKAIRKLTKTKAKLTQYNVGSITGGTDA 469
[138][TOP]
>UniRef100_A3XD03 2-isopropylmalate synthase n=1 Tax=Roseobacter sp. MED193
RepID=A3XD03_9RHOB
Length = 524
Score = 91.7 bits (226), Expect = 2e-17
Identities = 52/128 (40%), Positives = 77/128 (60%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LG+ + D QL +LF RFK +A++KK V D D++AL+ +L+ M++ CGT G
Sbjct: 348 LGFDVGDNQLKDLFVRFKELADRKKEVFDDDIVALMRSGEDAENDHLQLVSMKVICGTGG 407
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
+ +TV++ + DG++ A G GPVDA +KA+ + A L Y +NAVTEG DA AT
Sbjct: 408 PAEATVEM-EIDGQDLTAVESGDGPVDATFKAIRKLYPNTARLQLYQVNAVTEGTDAQAT 466
Query: 368 TRVLIRGD 391
V + D
Sbjct: 467 VSVRLEED 474
[139][TOP]
>UniRef100_A5V3R3 2-isopropylmalate synthase n=1 Tax=Sphingomonas wittichii RW1
RepID=A5V3R3_SPHWW
Length = 513
Score = 91.3 bits (225), Expect = 3e-17
Identities = 51/127 (40%), Positives = 78/127 (61%), Gaps = 1/127 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L D + F RFKA+A+ KK V D D++ALV DEV + ++ ++++ CG+
Sbjct: 343 ELGYALGDNAFQDAFGRFKALADAKKAVYDEDIVALVDDEVLRGHDSIQVKEVEVYCGSN 402
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLE-YSMNAVTEGIDAI 361
G + + L + DG+E + G GPVDA + A+ +IV +++LE Y ++AVT G DA
Sbjct: 403 GPQRAILTL-EVDGEEKTVTARGNGPVDALFNAIRMIVPHDSSVLERYEVHAVTGGTDAQ 461
Query: 362 ATTRVLI 382
A VL+
Sbjct: 462 AEVSVLL 468
[140][TOP]
>UniRef100_A3K8V5 2-isopropylmalate synthase n=1 Tax=Sagittula stellata E-37
RepID=A3K8V5_9RHOB
Length = 520
Score = 91.3 bits (225), Expect = 3e-17
Identities = 54/129 (41%), Positives = 80/129 (62%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LG + D QL ++F RFK +A++KK V D D++ALVS +A+ L+++++ CGT
Sbjct: 345 DLGTEVGDNQLKDIFVRFKDLADRKKEVFDDDILALVSATTEGADAI-TLVNLRVVCGTG 403
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G + + V+L + DGK+ A S G GPVDA +KA+ + A L Y +NAVT G DA A
Sbjct: 404 GPAEAQVEL-EIDGKDLTATSEGDGPVDATFKAIRALHPNMARLQLYQVNAVTAGTDAQA 462
Query: 365 TTRVLIRGD 391
T V + D
Sbjct: 463 TVSVRLEED 471
[141][TOP]
>UniRef100_Q49Z12 2-isopropylmalate synthase n=1 Tax=Staphylococcus saprophyticus
subsp. saprophyticus ATCC 15305 RepID=LEU1_STAS1
Length = 511
Score = 91.3 bits (225), Expect = 3e-17
Identities = 49/129 (37%), Positives = 76/129 (58%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY +D + LF +FK VA++KK VTD D+ AL+ + A++K+ +Q+ + G
Sbjct: 344 LGYDVDPEEQKTLFKQFKTVADKKKAVTDRDIHALIQGTEHEQNAIYKVETLQLQFVSNG 403
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
L ++ V + D DG + S+GTG + + Y AVD I L+EY +++VTEG DA A
Sbjct: 404 LQSAVVVIKDIDGNTYQDSSIGTGSIVSVYNAVDRIFDRKTELIEYRIDSVTEGTDAQAE 463
Query: 368 TRVLIRGDN 394
V I+ D+
Sbjct: 464 VHVQIKIDD 472
[142][TOP]
>UniRef100_Q5KWJ3 2-isopropylmalate synthase n=3 Tax=Geobacillus RepID=LEU1_GEOKA
Length = 515
Score = 90.9 bits (224), Expect = 4e-17
Identities = 50/128 (39%), Positives = 76/128 (59%), Gaps = 1/128 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQP-EAVWKLLDMQITCGT 181
ELGY L D +++ LF RFK +A++KK +TD DLIAL+ +E F + ++L +Q+ GT
Sbjct: 342 ELGYTLSDEEINQLFVRFKELADKKKDITDDDLIALIFEEKFDHFKDFYQLSSIQVQYGT 401
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
+ T+ V L D G E + G G V+A Y ++ + P TLL+Y + +V G DA+
Sbjct: 402 NQIPTAVVVLKDGKGNEIQEAATGAGSVEALYNTLERCFQTPVTLLDYRIESVGGGRDAL 461
Query: 362 ATTRVLIR 385
A V +R
Sbjct: 462 AQVFVKVR 469
[143][TOP]
>UniRef100_C8S015 2-isopropylmalate synthase n=1 Tax=Rhodobacter sp. SW2
RepID=C8S015_9RHOB
Length = 525
Score = 90.5 bits (223), Expect = 5e-17
Identities = 52/135 (38%), Positives = 81/135 (60%), Gaps = 1/135 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDE-VFQPEAVWKLLDMQITCGT 181
+LG+ L D QL+++F RFKA+A++KK V D DLIAL+ D+ +L +++ CGT
Sbjct: 347 DLGFDLADNQLNDVFVRFKALADRKKEVYDDDLIALMQDQGTHAAHDTLQLKRLRVVCGT 406
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
G + + +A +G +H + G GPVDA++ AV ++ A L Y ++AVTEG DA
Sbjct: 407 EGPQEAELTMA-IEGVDHAIDATGDGPVDASFNAVKMLYPHGARLQLYQVHAVTEGTDAQ 465
Query: 362 ATTRVLIRGDNNYSS 406
AT V + D ++
Sbjct: 466 ATVSVRLEEDGRIAT 480
[144][TOP]
>UniRef100_B8IHS8 2-isopropylmalate synthase n=1 Tax=Methylobacterium nodulans ORS
2060 RepID=LEU1_METNO
Length = 520
Score = 90.5 bits (223), Expect = 5e-17
Identities = 54/138 (39%), Positives = 80/138 (57%), Gaps = 1/138 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L D Q + F RFKA+A++KK V D D+ ALV + + +LL + + GT
Sbjct: 350 ELGYRLSDNQFQDAFERFKALADRKKNVYDEDIEALVDENLATAHDRIRLLSLTVIAGTR 409
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T++L D DG++ + G GPVDA + A+ +V A L Y ++AVTEG DA A
Sbjct: 410 GPQRATMRL-DIDGRQATEEADGNGPVDAVFNAIHALVPHEAKLELYDVHAVTEGTDAQA 468
Query: 365 TTRVLIR-GDNNYSSTNA 415
V +R G+ + ++ A
Sbjct: 469 EVSVRLRQGERSVTARGA 486
[145][TOP]
>UniRef100_C5D5M0 2-isopropylmalate synthase n=1 Tax=Geobacillus sp. WCH70
RepID=LEU1_GEOSW
Length = 515
Score = 90.5 bits (223), Expect = 5e-17
Identities = 49/128 (38%), Positives = 76/128 (59%), Gaps = 1/128 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQP-EAVWKLLDMQITCGT 181
ELGY L D +++ LF RFK +A++KK +TD DL+AL+ +E F + ++L +Q+ GT
Sbjct: 342 ELGYTLSDEEVNKLFVRFKELADKKKDITDDDLVALIFEEKFDHFKDFYQLSSLQVQYGT 401
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
+ T+ V L D G E + G G V+A Y ++ K TLL+Y + +V+ G DA+
Sbjct: 402 NQIPTAVVVLKDGQGNEIQEAATGAGSVEALYNTLERCFKTSVTLLDYRIESVSGGRDAL 461
Query: 362 ATTRVLIR 385
A V +R
Sbjct: 462 AQVFVKVR 469
[146][TOP]
>UniRef100_B5J9E5 2-isopropylmalate synthase n=1 Tax=Octadecabacter antarcticus 307
RepID=B5J9E5_9RHOB
Length = 519
Score = 90.1 bits (222), Expect = 7e-17
Identities = 52/135 (38%), Positives = 78/135 (57%)
Frame = +2
Query: 2 NELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGT 181
+ELG+ + D +L ++F RFK +A++KK V D DLIALV + + + KL D+ + CG
Sbjct: 341 SELGFEMGDNELKDVFVRFKDLADRKKEVFDDDLIALVRQNSTEDDRL-KLKDLTVVCGM 399
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
G + + L + DG +H + G GPVDA + AV + A L Y ++AVTEG DA
Sbjct: 400 NGPQKADMVL-EIDGSDHSKSATGDGPVDATFNAVKALFAHDARLQLYQVHAVTEGTDAQ 458
Query: 362 ATTRVLIRGDNNYSS 406
AT V + D ++
Sbjct: 459 ATVSVRMEEDGRIAT 473
[147][TOP]
>UniRef100_A6CAS9 2-isopropylmalate synthase n=1 Tax=Planctomyces maris DSM 8797
RepID=A6CAS9_9PLAN
Length = 507
Score = 90.1 bits (222), Expect = 7e-17
Identities = 44/126 (34%), Positives = 75/126 (59%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LG+ LD+ +F F A+A++KK + D+D++AL+ ++ WK++ + GT
Sbjct: 346 LGHTLDEETFERIFNEFIALADKKKEIYDSDIVALIENQASDMPEKWKIVRFHTSAGTGT 405
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
++T+T++LAD GK H + G GPVDA ++A++ I A L +Y + +V+ G DA
Sbjct: 406 IATATIELADETGKIHCDAATGDGPVDAVFRALERISGITAALDQYHVGSVSSGKDAQGE 465
Query: 368 TRVLIR 385
RV +R
Sbjct: 466 VRVEVR 471
[148][TOP]
>UniRef100_Q0FMQ1 2-isopropylmalate synthase n=1 Tax=Roseovarius sp. HTCC2601
RepID=Q0FMQ1_9RHOB
Length = 521
Score = 89.7 bits (221), Expect = 9e-17
Identities = 51/134 (38%), Positives = 81/134 (60%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG + D QL ++F RFK +A++KK V D D++ALV+ + +++ +++TCGT
Sbjct: 346 ELGTEVGDNQLKDIFVRFKDLADRKKEVYDEDILALVTAAMTDGADHLEIVSLKVTCGTG 405
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G + +T+++ + G+E A G GPVDA +KAV + A L Y ++AVTEG DA A
Sbjct: 406 GPAEATLEM-EVGGEEMSATEHGDGPVDATFKAVRALYPNKARLQLYQVHAVTEGTDAQA 464
Query: 365 TTRVLIRGDNNYSS 406
T V + D ++
Sbjct: 465 TVSVRLEEDGKIAT 478
[149][TOP]
>UniRef100_B5K8F6 2-isopropylmalate synthase n=1 Tax=Octadecabacter antarcticus 238
RepID=B5K8F6_9RHOB
Length = 519
Score = 89.7 bits (221), Expect = 9e-17
Identities = 52/133 (39%), Positives = 77/133 (57%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LG+ + D +L ++F RFK +A++KK V D DLIALV + + + KL D+ + CG G
Sbjct: 343 LGFEMGDNELKDVFVRFKDLADRKKEVFDDDLIALVRQNNSEDDRL-KLKDLTVICGMNG 401
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
+ + L + DGK+H + G GPVDA + AV + A L Y ++AVTEG DA AT
Sbjct: 402 PQKADMVL-EIDGKDHATSATGDGPVDATFNAVKSLFAHDARLQLYQVHAVTEGTDAQAT 460
Query: 368 TRVLIRGDNNYSS 406
V + D ++
Sbjct: 461 VSVRMEEDGRIAT 473
[150][TOP]
>UniRef100_B6JB87 2-isopropylmalate synthase n=1 Tax=Oligotropha carboxidovorans OM5
RepID=LEU1_OLICO
Length = 519
Score = 89.7 bits (221), Expect = 9e-17
Identities = 53/129 (41%), Positives = 75/129 (58%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L D QL + F RFKA+A++KK + D D+ ALV E+ Q +L+ + + GT
Sbjct: 350 ELGYELADNQLQDAFVRFKALADRKKDIYDEDIEALVDQELAQTHDRLRLVSLTVIAGTH 409
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T+K+ + DGK + + G GPVDA + AV +V A L Y ++AVT G DA A
Sbjct: 410 GPQRATMKV-EVDGKVRIDEAEGNGPVDAVFNAVKTLVPHEAKLELYQVHAVTAGTDAQA 468
Query: 365 TTRVLIRGD 391
V + D
Sbjct: 469 EVSVRLSQD 477
[151][TOP]
>UniRef100_B8E2W9 2-isopropylmalate synthase n=1 Tax=Dictyoglomus turgidum DSM 6724
RepID=LEU1_DICTD
Length = 503
Score = 89.7 bits (221), Expect = 9e-17
Identities = 49/124 (39%), Positives = 76/124 (61%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L QL F RFK +A++KK +TD D+ ALVS+++ +KL +Q+ G
Sbjct: 340 ELGYSLPPDQLEEAFRRFKELADKKKEITDKDIEALVSNQIRIIPEYYKLRHLQVVSGIG 399
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
+ T+T+ +++ +G+E +G GPVDA YKA+ VK P +L ++S+ +VT G DA+
Sbjct: 400 IVPTATIIISE-NGEEIKTVEIGNGPVDAVYKAITKAVKVPHSLEDFSLKSVTGGTDALG 458
Query: 365 TTRV 376
V
Sbjct: 459 EAMV 462
[152][TOP]
>UniRef100_B5YEF4 2-isopropylmalate synthase n=1 Tax=Dictyoglomus thermophilum H-6-12
RepID=LEU1_DICT6
Length = 503
Score = 89.7 bits (221), Expect = 9e-17
Identities = 47/124 (37%), Positives = 77/124 (62%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L QL F +FK +A++KK +TD D+ ALVS+++ ++L+ +Q+ G
Sbjct: 340 ELGYSLPPEQLEEAFKKFKELADKKKEITDKDIEALVSNQIKLVPEYYRLVHLQVVSGIG 399
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
+ T+T+ +++ DG+E +G GPVDA YKA+ +K P +L ++S+ +VT G DA+
Sbjct: 400 IVPTATIIISE-DGEEIKTVEIGNGPVDAVYKAIAKAIKIPHSLEDFSLKSVTGGTDALG 458
Query: 365 TTRV 376
V
Sbjct: 459 EAMV 462
[153][TOP]
>UniRef100_B7GH19 2-isopropylmalate synthase n=1 Tax=Anoxybacillus flavithermus WK1
RepID=LEU1_ANOFW
Length = 514
Score = 89.7 bits (221), Expect = 9e-17
Identities = 50/135 (37%), Positives = 80/135 (59%), Gaps = 1/135 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQP-EAVWKLLDMQITCGT 181
ELGY L + +++ LF RFK +A++KK +TD DLIAL+ DE + ++L +Q+ GT
Sbjct: 342 ELGYSLTEEEVNRLFVRFKDLADKKKDITDDDLIALILDEKLDTYKNFYQLCSIQVQYGT 401
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
+ T+ V L D +G + + G G V+A Y A++ ++ P TLL+Y + +V G DA+
Sbjct: 402 NQIPTAVVVLKDGEGNDIQEAATGAGSVEALYNALEKALQLPVTLLDYRIESVGSGRDAL 461
Query: 362 ATTRVLIRGDNNYSS 406
A V + D +S
Sbjct: 462 AQVYVKVSLDRKEAS 476
[154][TOP]
>UniRef100_C4WCT2 2-isopropylmalate synthase n=1 Tax=Staphylococcus warneri L37603
RepID=C4WCT2_STAWA
Length = 511
Score = 89.4 bits (220), Expect = 1e-16
Identities = 48/129 (37%), Positives = 76/129 (58%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY + NLF +FK++A++KK V+D D+ AL+ + A+++L +Q+ + G
Sbjct: 344 LGYDISPDDQINLFKQFKSIADKKKSVSDRDIHALIQGSEHEQSAIYQLEALQLQFVSNG 403
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
L ++ V + D DG + S+GTG + A Y AVD I K L++Y +++VTEG DA A
Sbjct: 404 LQSAVVVIKDKDGNIYQDSSIGTGSIVAIYNAVDRIFKRETELIDYRIDSVTEGTDAQAE 463
Query: 368 TRVLIRGDN 394
V + DN
Sbjct: 464 VHVNLVIDN 472
[155][TOP]
>UniRef100_Q16AY3 2-isopropylmalate synthase n=1 Tax=Roseobacter denitrificans OCh
114 RepID=Q16AY3_ROSDO
Length = 522
Score = 89.0 bits (219), Expect = 1e-16
Identities = 51/123 (41%), Positives = 72/123 (58%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LG+ L D QL ++F RFKA+A++KK + D DLIAL+ KL+ +++ CGT G
Sbjct: 348 LGFELGDNQLKDVFVRFKALADRKKEIYDDDLIALMRTATDPENDRIKLVSLRVVCGTHG 407
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
+ + L + DG E G GPVDA++ A+ +V A L Y ++AVTEG DA AT
Sbjct: 408 PQQADLVL-NIDGVEKSTTQTGDGPVDASFNAIKALVSHSARLQLYQVHAVTEGTDAQAT 466
Query: 368 TRV 376
V
Sbjct: 467 VSV 469
[156][TOP]
>UniRef100_A9BGP5 2-isopropylmalate synthase n=1 Tax=Petrotoga mobilis SJ95
RepID=A9BGP5_PETMO
Length = 510
Score = 89.0 bits (219), Expect = 1e-16
Identities = 51/133 (38%), Positives = 82/133 (61%), Gaps = 3/133 (2%)
Frame = +2
Query: 11 GYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLGL 190
GY +++ LF +FK +A +KK + D+ AL++DE+++ E +KL + +T G L
Sbjct: 345 GYTVNEETFEKLFIKFKDLASKKKNLNPLDVEALINDELYKTEDYFKLKYLSVTTGNTTL 404
Query: 191 STSTVKLA-DSDGKEHVACSVGTGPVDAAYKAVDLIVKEP-ATLLEYSMNAVTEGIDAIA 364
T+T+K+A D E ACS G GP+DA +KA++ I +E TL+ Y + VTEG DA+
Sbjct: 405 PTATIKIARGEDLIEKAACS-GDGPIDAIFKAINEIAEEENITLISYKIEGVTEGTDALG 463
Query: 365 TTRVLIR-GDNNY 400
T V ++ G++ Y
Sbjct: 464 ETTVKLKIGEDVY 476
[157][TOP]
>UniRef100_C2K9W8 2-isopropylmalate synthase n=1 Tax=Staphylococcus aureus subsp.
aureus MN8 RepID=C2K9W8_STAAU
Length = 509
Score = 89.0 bits (219), Expect = 1e-16
Identities = 49/129 (37%), Positives = 79/129 (61%), Gaps = 2/129 (1%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY +D +LF +FKA+A++KK V+D D+ A++ + +A++KL +Q+ + G
Sbjct: 344 LGYDIDKEAQIDLFKQFKAIADKKKSVSDRDIHAIIQGSEHEHQALYKLETLQLQYVSSG 403
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
L ++ V + D +G + S+GTG + A Y AVD I ++ L++Y +N+VTEG DA A
Sbjct: 404 LQSAVVVIKDKEGHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDYRINSVTEGTDAQAE 463
Query: 368 TRV--LIRG 388
V LI G
Sbjct: 464 VHVNLLIEG 472
[158][TOP]
>UniRef100_C2G5S5 2-isopropylmalate synthase n=6 Tax=Staphylococcus aureus subsp.
aureus RepID=C2G5S5_STAAU
Length = 509
Score = 89.0 bits (219), Expect = 1e-16
Identities = 49/129 (37%), Positives = 79/129 (61%), Gaps = 2/129 (1%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY +D +LF +FKA+A++KK V+D D+ A++ + +A++KL +Q+ + G
Sbjct: 344 LGYDIDKEAQIDLFKQFKAIADKKKSVSDRDIHAIIQGSEHEHQALYKLETLQLQYVSSG 403
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
L ++ V + D +G + S+GTG + A Y AVD I ++ L++Y +N+VTEG DA A
Sbjct: 404 LQSAVVVIKDKEGHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDYRINSVTEGTDAQAE 463
Query: 368 TRV--LIRG 388
V LI G
Sbjct: 464 VHVNLLIEG 472
[159][TOP]
>UniRef100_C1ZC48 2-isopropylmalate synthase n=1 Tax=Planctomyces limnophilus DSM
3776 RepID=C1ZC48_PLALI
Length = 521
Score = 89.0 bits (219), Expect = 1e-16
Identities = 51/133 (38%), Positives = 72/133 (54%), Gaps = 1/133 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY LDD +F F +A++KK V DAD+IA++ + WKL I GT
Sbjct: 352 ELGYTLDDETFQRVFDEFIILADKKKSVYDADIIAIIEHQDRNASDRWKLQRFHIAAGTG 411
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
+ T+TV+L D + H ++G GPVDA KA++ I+ TL Y + +V+EG DA
Sbjct: 412 TIPTATVELHDDQHQVHCDAAIGDGPVDAVCKAIERIMGVSGTLDNYQVRSVSEGKDAQG 471
Query: 365 TTRV-LIRGDNNY 400
+ LI G Y
Sbjct: 472 EVMIELITGGRKY 484
[160][TOP]
>UniRef100_A6DY52 2-isopropylmalate synthase n=1 Tax=Roseovarius sp. TM1035
RepID=A6DY52_9RHOB
Length = 521
Score = 89.0 bits (219), Expect = 1e-16
Identities = 51/124 (41%), Positives = 75/124 (60%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LGY L D QL+++F RFK +A++KK + D DL+ALV+ V ++ +++ CGT
Sbjct: 346 DLGYELADNQLNDVFVRFKELADRKKEIYDDDLVALVNAGVDPDNNRLQIKHLRVICGTD 405
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T+ + D DG+E + G GPVDA + AV + A L Y ++AVTEG DA A
Sbjct: 406 GPQQATLTM-DIDGREVSTEATGDGPVDATFNAVKALFPHEARLQLYQVHAVTEGTDAQA 464
Query: 365 TTRV 376
T V
Sbjct: 465 TVSV 468
[161][TOP]
>UniRef100_Q6GF16 2-isopropylmalate synthase n=1 Tax=Staphylococcus aureus subsp.
aureus MRSA252 RepID=LEU1_STAAR
Length = 509
Score = 89.0 bits (219), Expect = 1e-16
Identities = 49/129 (37%), Positives = 79/129 (61%), Gaps = 2/129 (1%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY +D +LF +FKA+A++KK V+D D+ A++ + +A++KL +Q+ + G
Sbjct: 344 LGYDIDKEAQIDLFKQFKAIADKKKSVSDRDIHAIIQGSEHEHQALYKLETLQLQYVSSG 403
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
L ++ V + D +G + S+GTG + A Y AVD I ++ L++Y +N+VTEG DA A
Sbjct: 404 LQSAVVVIKDKEGHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDYRINSVTEGTDAQAE 463
Query: 368 TRV--LIRG 388
V LI G
Sbjct: 464 VHVNLLIEG 472
[162][TOP]
>UniRef100_B3QCX5 2-isopropylmalate synthase n=1 Tax=Rhodopseudomonas palustris TIE-1
RepID=LEU1_RHOPT
Length = 524
Score = 89.0 bits (219), Expect = 1e-16
Identities = 51/137 (37%), Positives = 78/137 (56%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L Q+ ++F RFKA+A++KK V D D+ ALV +++ + KL+ + + GT
Sbjct: 350 ELGYKLSRNQIEDVFVRFKALADRKKDVYDEDIEALVDEQLLHGQDQIKLMSLTVIAGTH 409
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T+KL D DG+ + + G GPVDA + + +V A L Y ++AVTEG DA A
Sbjct: 410 GPQRATMKL-DVDGQIRIEEAEGNGPVDAVFNCIKALVPHDAKLELYQVHAVTEGTDAQA 468
Query: 365 TTRVLIRGDNNYSSTNA 415
V + + + A
Sbjct: 469 EVSVRLSHEGRSMTARA 485
[163][TOP]
>UniRef100_Q212A9 2-isopropylmalate synthase n=1 Tax=Rhodopseudomonas palustris
BisB18 RepID=LEU1_RHOPB
Length = 521
Score = 89.0 bits (219), Expect = 1e-16
Identities = 51/137 (37%), Positives = 76/137 (55%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
E+GY L QL + F RFKA+A++KK + D D+ ALV E+ Q KLL + + GT
Sbjct: 350 EMGYKLGQNQLEDAFVRFKALADRKKEIYDEDIEALVDQEIAQSHDRIKLLSLTVIAGTH 409
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T+KL D +G+ + + G GPVDA + + +V A L Y ++AVT+G DA A
Sbjct: 410 GPQRATMKL-DVEGQTRIEEAEGNGPVDAVFNCIKALVPHVAKLELYQVHAVTQGTDAQA 468
Query: 365 TTRVLIRGDNNYSSTNA 415
V + + + A
Sbjct: 469 EVSVRLAHEGRSMTARA 485
[164][TOP]
>UniRef100_Q6N858 2-isopropylmalate synthase n=1 Tax=Rhodopseudomonas palustris
RepID=LEU1_RHOPA
Length = 524
Score = 89.0 bits (219), Expect = 1e-16
Identities = 51/137 (37%), Positives = 78/137 (56%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L Q+ ++F RFKA+A++KK V D D+ ALV +++ + KL+ + + GT
Sbjct: 350 ELGYKLSRNQIEDVFVRFKALADRKKDVYDEDIEALVDEQLLHGQDQIKLMSLTVIAGTH 409
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T+KL D DG+ + + G GPVDA + + +V A L Y ++AVTEG DA A
Sbjct: 410 GPQRATMKL-DVDGQIRIEEAEGNGPVDAVFNCIKALVPHDAKLELYQVHAVTEGTDAQA 468
Query: 365 TTRVLIRGDNNYSSTNA 415
V + + + A
Sbjct: 469 EVSVRLSHEGRSMTARA 485
[165][TOP]
>UniRef100_B5YJS7 2-isopropylmalate synthase n=1 Tax=Thermodesulfovibrio yellowstonii
DSM 11347 RepID=B5YJS7_THEYD
Length = 504
Score = 88.6 bits (218), Expect = 2e-16
Identities = 45/126 (35%), Positives = 79/126 (62%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L + +++ F RFK +A+QKK + + D+ ALVSDEV + V++L+D+++ GT
Sbjct: 342 ELGFSLTEEEINRAFERFKKLADQKKYIFNEDIEALVSDEVLRIAEVYQLIDLEVASGTK 401
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TVK+ + ++ + S G GPVD+ Y+A+ + A L ++ + A+T G DA+
Sbjct: 402 KKPTATVKMKINGDEKEITVS-GDGPVDSVYRAITELTGSKAELNKFEIKAITGGTDALG 460
Query: 365 TTRVLI 382
V++
Sbjct: 461 EVTVIL 466
[166][TOP]
>UniRef100_C8MBT6 2-isopropylmalate synthase n=1 Tax=Staphylococcus aureus A9635
RepID=C8MBT6_STAAU
Length = 509
Score = 88.6 bits (218), Expect = 2e-16
Identities = 49/129 (37%), Positives = 79/129 (61%), Gaps = 2/129 (1%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY +D +LF +FKA+A++KK V+D D+ A++ + +A++KL +Q+ + G
Sbjct: 344 LGYDIDKEAQIDLFKQFKAIADKKKSVSDRDIHAIIQGSEHEHQALYKLETLQLQYVSSG 403
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
L ++ V + D +G + S+GTG + A Y AVD I ++ L++Y +N+VTEG DA A
Sbjct: 404 LQSAVVVVKDKEGHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDYRINSVTEGTDAQAE 463
Query: 368 TRV--LIRG 388
V LI G
Sbjct: 464 VHVNLLIEG 472
[167][TOP]
>UniRef100_B0PBC1 Putative uncharacterized protein n=1 Tax=Anaerotruncus colihominis
DSM 17241 RepID=B0PBC1_9FIRM
Length = 557
Score = 88.6 bits (218), Expect = 2e-16
Identities = 49/120 (40%), Positives = 73/120 (60%), Gaps = 1/120 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALV-SDEVFQPEAVWKLLDMQITCGT 181
ELGY + + ++ F RFKA+A++KK +TD D+ AL+ + + V+ L I GT
Sbjct: 391 ELGYRMSEEDIAEAFERFKALADRKKEITDRDIEALIGASAITDVREVYALKSFVINSGT 450
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
+ +T+ VKL+ DG E + G GP+DAA+ A+D IVK L ++M AVTEG DA+
Sbjct: 451 VISATAVVKLSRDDGTECEHVARGEGPIDAAFNAIDRIVKMDTKLENWTMQAVTEGEDAL 510
[168][TOP]
>UniRef100_B1H0A7 2-isopropylmalate synthase n=1 Tax=uncultured Termite group 1
bacterium phylotype Rs-D17 RepID=LEU1_UNCTG
Length = 516
Score = 88.6 bits (218), Expect = 2e-16
Identities = 47/125 (37%), Positives = 77/125 (61%), Gaps = 6/125 (4%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LGY LD+ L +LF +FK +A++KK V D D+IAL+ ++ + + L + T GT
Sbjct: 344 DLGYKLDEKTLEHLFEKFKILADKKKTVFDDDIIALIEEDTSSGKETFILNYLSATSGTG 403
Query: 185 GLSTSTVKLADSDGKEHV------ACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTE 346
+ T+TVK++ S+G + A + G+GPVDA YKA+D I+ L ++S+ +V+
Sbjct: 404 TIPTATVKISKSEGNKKTKSITLQAAACGSGPVDATYKAIDKIINMDIKLTDFSLRSVSS 463
Query: 347 GIDAI 361
G DA+
Sbjct: 464 GEDAL 468
[169][TOP]
>UniRef100_Q6G7Q1 2-isopropylmalate synthase n=3 Tax=Staphylococcus aureus subsp.
aureus RepID=LEU1_STAAS
Length = 509
Score = 88.6 bits (218), Expect = 2e-16
Identities = 49/129 (37%), Positives = 79/129 (61%), Gaps = 2/129 (1%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY +D +LF +FKA+A++KK V+D D+ A++ + +A++KL +Q+ + G
Sbjct: 344 LGYGIDKEAQIDLFKQFKAIADKKKSVSDRDIHAIIQGSEHEHQALYKLETLQLQYVSSG 403
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
L ++ V + D +G + S+GTG + A Y AVD I ++ L++Y +N+VTEG DA A
Sbjct: 404 LQSAVVVVKDKEGHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDYRINSVTEGTDAQAE 463
Query: 368 TRV--LIRG 388
V LI G
Sbjct: 464 VHVNLLIEG 472
[170][TOP]
>UniRef100_Q2YUF2 2-isopropylmalate synthase n=1 Tax=Staphylococcus aureus RF122
RepID=LEU1_STAAB
Length = 509
Score = 88.6 bits (218), Expect = 2e-16
Identities = 49/129 (37%), Positives = 79/129 (61%), Gaps = 2/129 (1%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY +D +LF +FKA+A++KK V+D D+ A++ + +A++KL +Q+ + G
Sbjct: 344 LGYDIDKEAQIDLFKQFKAIADKKKSVSDRDIHAIIQGSEHEHQALYKLETLQLQYVSSG 403
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
L ++ V + D +G + S+GTG + A Y AVD I ++ L++Y +N+VTEG DA A
Sbjct: 404 LQSAVVVVKDKEGHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDYRINSVTEGTDAQAE 463
Query: 368 TRV--LIRG 388
V LI G
Sbjct: 464 VHVNLLIEG 472
[171][TOP]
>UniRef100_Q2FWK3 2-isopropylmalate synthase n=8 Tax=Staphylococcus aureus
RepID=LEU1_STAA8
Length = 509
Score = 88.6 bits (218), Expect = 2e-16
Identities = 49/129 (37%), Positives = 79/129 (61%), Gaps = 2/129 (1%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY +D +LF +FKA+A++KK V+D D+ A++ + +A++KL +Q+ + G
Sbjct: 344 LGYDIDKEAQIDLFKQFKAIADKKKSVSDRDIHAIIQGSEHEHQALYKLETLQLQYVSSG 403
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
L ++ V + D +G + S+GTG + A Y AVD I ++ L++Y +N+VTEG DA A
Sbjct: 404 LQSAVVVVKDKEGHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDYRINSVTEGTDAQAE 463
Query: 368 TRV--LIRG 388
V LI G
Sbjct: 464 VHVNLLIEG 472
[172][TOP]
>UniRef100_A9FHR3 2-isopropylmalate synthase n=2 Tax=Phaeobacter gallaeciensis
RepID=A9FHR3_9RHOB
Length = 523
Score = 88.2 bits (217), Expect = 3e-16
Identities = 51/125 (40%), Positives = 81/125 (64%)
Frame = +2
Query: 2 NELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGT 181
++LG+ + D QL +LF RFK +A++KK V D D+IAL+ + + + KL+ M++ CGT
Sbjct: 346 SQLGFEVGDNQLKDLFVRFKELADRKKEVFDDDIIALMRTSGDEDDHL-KLVSMKVVCGT 404
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
G + +T+++ + +GK+ + G GPVDAA++A+ I A L Y ++AVTEG DA
Sbjct: 405 GGPAEATLEM-EVEGKDVSETAEGDGPVDAAFRAIRKIHPNSAHLQLYQVHAVTEGTDAQ 463
Query: 362 ATTRV 376
AT V
Sbjct: 464 ATVSV 468
[173][TOP]
>UniRef100_A3VYC0 2-isopropylmalate synthase n=1 Tax=Roseovarius sp. 217
RepID=A3VYC0_9RHOB
Length = 530
Score = 87.8 bits (216), Expect = 3e-16
Identities = 50/124 (40%), Positives = 75/124 (60%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LGY L D QL+++F RFK +A++KK + D DL+ALV+ V ++ +++ CGT
Sbjct: 355 DLGYELADNQLNDVFVRFKELADRKKEIYDDDLVALVNAGVDSENNRLQIKHLRVICGTD 414
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T+ + + DG+E + G GPVDA + AV + A L Y ++AVTEG DA A
Sbjct: 415 GPQQATLTM-EIDGREVSTEATGDGPVDATFNAVKALFPHEARLQLYQVHAVTEGTDAQA 473
Query: 365 TTRV 376
T V
Sbjct: 474 TVSV 477
[174][TOP]
>UniRef100_Q07PI3 2-isopropylmalate synthase n=1 Tax=Rhodopseudomonas palustris
BisA53 RepID=LEU1_RHOP5
Length = 521
Score = 87.8 bits (216), Expect = 3e-16
Identities = 52/137 (37%), Positives = 77/137 (56%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
E+GY L QL + F RFKA+A++KK + D D+ ALV E+ Q KL+ + + GT
Sbjct: 350 EMGYKLGQNQLEDAFVRFKALADRKKDIYDEDIEALVDLEIAQSHDRIKLVSLTVIAGTH 409
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T+KL D DG+ + + G GPVDA + + +V A L Y ++AVTEG DA A
Sbjct: 410 GPQRATMKL-DVDGQTKIEEAEGNGPVDAVFNCIKALVPHVAKLELYQVHAVTEGTDAQA 468
Query: 365 TTRVLIRGDNNYSSTNA 415
V + + ++ A
Sbjct: 469 EVSVRLSHEGRSVTSRA 485
[175][TOP]
>UniRef100_Q2RG97 2-isopropylmalate synthase n=1 Tax=Moorella thermoacetica ATCC
39073 RepID=Q2RG97_MOOTA
Length = 517
Score = 87.4 bits (215), Expect = 4e-16
Identities = 51/130 (39%), Positives = 76/130 (58%), Gaps = 1/130 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L + +L F RFK +A++KK ++D DL A+V EV + + L + I+ G
Sbjct: 346 ELGFKLTEAELDKAFARFKELADRKKEISDRDLEAIVEHEVKRIPEKFVLEHIHISTGNR 405
Query: 185 GLSTSTVKL-ADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
+ T+T+ + + KE AC G GPVDAA+KA+D + + P L Y++NAVT G DA+
Sbjct: 406 VVPTATIGIRVGEELKEEAAC--GEGPVDAAFKAIDKLTRIPVCLKSYNLNAVTGGKDAV 463
Query: 362 ATTRVLIRGD 391
V I D
Sbjct: 464 GEVTVKIEYD 473
[176][TOP]
>UniRef100_C6XN10 2-isopropylmalate synthase n=1 Tax=Hirschia baltica ATCC 49814
RepID=C6XN10_HIRBI
Length = 513
Score = 87.4 bits (215), Expect = 4e-16
Identities = 49/128 (38%), Positives = 79/128 (61%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGYVLDD +++ F RFK +A++KK V D D++ALV D++ + + L +++ GT G
Sbjct: 347 LGYVLDDEAMNDAFRRFKDLADKKKDVFDEDIMALVDDQLSGTDELISLHALKVVAGTEG 406
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
+ ++L +++G+ A + G GPVDA + A+ I+ A L + ++AVTEG DA AT
Sbjct: 407 PQIAEIEL-ETEGEIKSARAEGNGPVDAVFNAIRAIIPHDAVLELFQIHAVTEGTDAQAT 465
Query: 368 TRVLIRGD 391
V + D
Sbjct: 466 VSVRLSED 473
[177][TOP]
>UniRef100_A9DV85 2-isopropylmalate synthase n=1 Tax=Oceanibulbus indolifex HEL-45
RepID=A9DV85_9RHOB
Length = 522
Score = 87.4 bits (215), Expect = 4e-16
Identities = 50/124 (40%), Positives = 72/124 (58%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LG+ L D QL ++F RFK +A++KK + + DLIAL+ E +L +++ CGT
Sbjct: 347 DLGFELGDNQLKDVFVRFKELADRKKEIYEDDLIALMRTATDPEEDRIRLKSLKVVCGTE 406
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G T+ + L + DG E G GPVDAA+ + +V A L Y ++AVTEG DA A
Sbjct: 407 GPQTADMVL-EVDGAEQSTNQTGDGPVDAAFNCIKALVLHTARLQLYQVHAVTEGTDAQA 465
Query: 365 TTRV 376
T V
Sbjct: 466 TVSV 469
[178][TOP]
>UniRef100_A4EEV9 2-isopropylmalate synthase n=1 Tax=Roseobacter sp. CCS2
RepID=A4EEV9_9RHOB
Length = 519
Score = 87.4 bits (215), Expect = 4e-16
Identities = 52/125 (41%), Positives = 76/125 (60%)
Frame = +2
Query: 2 NELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGT 181
NELG+ L D QL+++F RFK +A++KK V D DL+ALV+ + + + KL +++ CGT
Sbjct: 343 NELGFDLADNQLNDVFVRFKDLADRKKEVFDDDLMALVTQNDAEDDRL-KLKSLRVVCGT 401
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
G + + + + DG + + G GPVDA + AV I A L Y ++AVTEG DA
Sbjct: 402 DGPQKADM-VMEVDGADVETSATGDGPVDATFNAVKAIFSHGARLQIYQVSAVTEGTDAQ 460
Query: 362 ATTRV 376
AT V
Sbjct: 461 ATVSV 465
[179][TOP]
>UniRef100_Q3SQ49 2-isopropylmalate synthase n=1 Tax=Nitrobacter winogradskyi Nb-255
RepID=LEU1_NITWN
Length = 519
Score = 87.4 bits (215), Expect = 4e-16
Identities = 52/137 (37%), Positives = 77/137 (56%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L + QL + F RFKA+A++KK + D D+IALV +E+ KL + + GT
Sbjct: 350 ELGYKLAENQLQDAFVRFKALADRKKDIYDEDIIALVDEEMAATHDRIKLSSLTVIAGTH 409
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T+KL S G+ + + G GPVDA + + +V A L Y ++AVT+G DA A
Sbjct: 410 GPQRATMKLTVS-GQTRIEEAEGNGPVDAVFNCIKRLVPHEAKLELYQVHAVTQGTDAQA 468
Query: 365 TTRVLIRGDNNYSSTNA 415
V + D ++ A
Sbjct: 469 EVSVRLSQDGRAMTSKA 485
[180][TOP]
>UniRef100_Q1QJV3 2-isopropylmalate synthase n=1 Tax=Nitrobacter hamburgensis X14
RepID=LEU1_NITHX
Length = 520
Score = 87.4 bits (215), Expect = 4e-16
Identities = 51/137 (37%), Positives = 76/137 (55%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L + QL + F RFKA+A++KK + D D++ALV +E+ KL + + GT
Sbjct: 350 ELGYKLAENQLQDAFVRFKALADRKKDIYDEDIVALVDEEMAASHDRIKLTSLTVIAGTH 409
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T+KL DG+ + + G GPVDA + + +V A L Y ++AVT G DA A
Sbjct: 410 GPQRATMKLT-VDGQTRIEEAEGNGPVDAVFNCIKRLVPHEAKLDLYQVHAVTHGTDAQA 468
Query: 365 TTRVLIRGDNNYSSTNA 415
V + D ++ A
Sbjct: 469 EVSVRLSQDGRAMTSKA 485
[181][TOP]
>UniRef100_B8EP66 2-isopropylmalate synthase n=1 Tax=Methylocella silvestris BL2
RepID=B8EP66_METSB
Length = 526
Score = 87.0 bits (214), Expect = 6e-16
Identities = 52/129 (40%), Positives = 73/129 (56%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L D L + F RFK +A++KK V D DL+ALV DE+ KL+D+ + GT
Sbjct: 357 ELGYELADNALHDAFVRFKDLADRKKVVYDEDLMALVDDEIVHAHDRIKLVDLTVFAGTK 416
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G ++ + L D DG + G GPVDA + A+ +V A L + ++AVT+G DA A
Sbjct: 417 GPQSAALTL-DIDGTHVTHQATGNGPVDAIFNAIQALVPHGAVLELFQVHAVTKGTDAQA 475
Query: 365 TTRVLIRGD 391
V + D
Sbjct: 476 EVSVRLAED 484
[182][TOP]
>UniRef100_B7KQH6 2-isopropylmalate synthase n=1 Tax=Methylobacterium
chloromethanicum CM4 RepID=B7KQH6_METC4
Length = 520
Score = 87.0 bits (214), Expect = 6e-16
Identities = 53/138 (38%), Positives = 80/138 (57%), Gaps = 1/138 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG L D Q ++F RFKA+A++KK V D D+ ALV ++ KL+ + + GT
Sbjct: 350 ELGISLSDNQFQDVFERFKALADRKKHVYDEDIEALVDEKRATAHDRIKLVSLSVIAGTR 409
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T+K+ + DG+ A + G GPVDA + A+ IV A L Y ++AVTEG DA A
Sbjct: 410 GPQRATMKI-EMDGRVFTAEADGNGPVDAVFNAIHEIVPHDAVLELYQVHAVTEGTDAQA 468
Query: 365 TTRVLIR-GDNNYSSTNA 415
V ++ G+ + ++ A
Sbjct: 469 EVSVRLKAGERSVTARGA 486
[183][TOP]
>UniRef100_C5Q4E2 2-isopropylmalate synthase n=1 Tax=Staphylococcus aureus subsp.
aureus TCH130 RepID=C5Q4E2_STAAU
Length = 509
Score = 87.0 bits (214), Expect = 6e-16
Identities = 48/129 (37%), Positives = 78/129 (60%), Gaps = 2/129 (1%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY +D +LF +FK +A++KK V+D D+ A++ + +A++KL +Q+ + G
Sbjct: 344 LGYDIDKEAQIDLFKQFKTIADKKKSVSDRDIHAIIQGSEHEHQALYKLETLQLQYVSSG 403
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
L ++ V + D +G + S+GTG + A Y AVD I ++ L++Y +N+VTEG DA A
Sbjct: 404 LQSAVVVVKDKEGHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDYRINSVTEGTDAQAE 463
Query: 368 TRV--LIRG 388
V LI G
Sbjct: 464 VHVNLLIEG 472
[184][TOP]
>UniRef100_C1ZZQ9 2-isopropylmalate synthase n=1 Tax=Sulfurospirillum deleyianum DSM
6946 RepID=C1ZZQ9_SULDE
Length = 520
Score = 87.0 bits (214), Expect = 6e-16
Identities = 49/129 (37%), Positives = 83/129 (64%), Gaps = 1/129 (0%)
Frame = +2
Query: 2 NELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQIT-CG 178
N LGY L D +++ F RFK +A+QKK + D DL ALV+DE+ + V++L+ +Q++ C
Sbjct: 343 NSLGYELKDEEINEAFERFKILADQKKDIFDDDLRALVADEITKIPQVFELVRLQLSDCS 402
Query: 179 TLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDA 358
GL ++ V ++ +GKE ++G G +DA +K +D + L +Y ++AV++G DA
Sbjct: 403 PGGLPSAAVTIS-HEGKEITDAAIGNGTMDAIFKVIDRVCGVSGELRDYKVDAVSQGKDA 461
Query: 359 IATTRVLIR 385
+A RVL++
Sbjct: 462 MA--RVLVK 468
[185][TOP]
>UniRef100_A3WU66 2-isopropylmalate synthase n=1 Tax=Nitrobacter sp. Nb-311A
RepID=A3WU66_9BRAD
Length = 519
Score = 87.0 bits (214), Expect = 6e-16
Identities = 52/137 (37%), Positives = 77/137 (56%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L + QL + F RFKA+A++KK + D D+IALV +E+ KL + + GT
Sbjct: 350 ELGYRLAENQLQDAFVRFKALADRKKDIYDEDIIALVDEEMAATHDRIKLSSLTVIAGTH 409
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T+KL S G+ + + G GPVDA + + +V A L Y ++AVT+G DA A
Sbjct: 410 GPQRATMKLTIS-GQTRIEEAEGNGPVDAVFNCIKRLVPHEAKLELYQVHAVTQGTDAQA 468
Query: 365 TTRVLIRGDNNYSSTNA 415
V + D ++ A
Sbjct: 469 EVSVRLSQDGRAMTSKA 485
[186][TOP]
>UniRef100_A7X4N1 2-isopropylmalate synthase n=13 Tax=Staphylococcus aureus
RepID=LEU1_STAA1
Length = 509
Score = 87.0 bits (214), Expect = 6e-16
Identities = 48/129 (37%), Positives = 78/129 (60%), Gaps = 2/129 (1%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY +D +LF +FK +A++KK V+D D+ A++ + +A++KL +Q+ + G
Sbjct: 344 LGYNIDKEAQIDLFKQFKTIADKKKSVSDRDIHAIIQGSEHEHQALYKLETLQLQYVSSG 403
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
L ++ V + D +G + S+GTG + A Y AVD I ++ L++Y +N+VTEG DA A
Sbjct: 404 LQSAVVVVKDKEGHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDYRINSVTEGTDAQAE 463
Query: 368 TRV--LIRG 388
V LI G
Sbjct: 464 VHVNLLIEG 472
[187][TOP]
>UniRef100_Q2IUT4 2-isopropylmalate synthase n=1 Tax=Rhodopseudomonas palustris HaA2
RepID=LEU1_RHOP2
Length = 524
Score = 87.0 bits (214), Expect = 6e-16
Identities = 51/137 (37%), Positives = 77/137 (56%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L Q+ ++F RFKA+A++KK V D D+ ALV +++ + KL + + GT
Sbjct: 350 ELGYKLSRNQIEDVFVRFKALADRKKDVYDEDIEALVDEQLLHGQDQIKLNSLTVIAGTH 409
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T+KL D DG+ + + G GPVDA + + +V A L Y ++AVTEG DA A
Sbjct: 410 GPQRATMKL-DVDGQIRIEEAEGNGPVDAVFNCIKALVPHDAKLELYQVHAVTEGTDAQA 468
Query: 365 TTRVLIRGDNNYSSTNA 415
V + + + A
Sbjct: 469 EVSVRLSHEGRSMTARA 485
[188][TOP]
>UniRef100_A4YZ76 2-isopropylmalate synthase n=1 Tax=Bradyrhizobium sp. ORS278
RepID=LEU1_BRASO
Length = 525
Score = 87.0 bits (214), Expect = 6e-16
Identities = 50/137 (36%), Positives = 75/137 (54%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
E+G+ L Q+ + F RFKA+A++KK++ D D+ AL+ + + KLL + + GT
Sbjct: 350 EMGHKLSSNQVEDAFVRFKALADRKKQIYDEDIEALIDEGMVSAHDRIKLLSLSVIAGTR 409
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T+KL D DG + S G GPVDA + + +V A L Y ++AVTEG DA A
Sbjct: 410 GPQRATMKL-DIDGVTRIEESEGNGPVDAVFNCIKSLVPHEAKLELYQVHAVTEGTDAQA 468
Query: 365 TTRVLIRGDNNYSSTNA 415
V + D + A
Sbjct: 469 EVSVRLSQDGRSMTARA 485
[189][TOP]
>UniRef100_B2IFN7 2-isopropylmalate synthase n=1 Tax=Beijerinckia indica subsp.
indica ATCC 9039 RepID=B2IFN7_BEII9
Length = 532
Score = 86.7 bits (213), Expect = 7e-16
Identities = 52/129 (40%), Positives = 71/129 (55%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L + L F RFK +A++KK V D DLIALV DE+ KL+ + + GT
Sbjct: 362 ELGYELGENALEEAFARFKDLADRKKIVYDEDLIALVDDEIIHAHDRIKLVALTVIAGTK 421
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G ++ + L DG E + G GP+DA + AV +V A L Y ++AVT+G DA A
Sbjct: 422 GPQSAALTLT-IDGVEQTHQATGNGPIDAIFNAVQALVPHGAVLELYQVHAVTKGTDAQA 480
Query: 365 TTRVLIRGD 391
V + D
Sbjct: 481 EVSVRLSED 489
[190][TOP]
>UniRef100_A9W659 2-isopropylmalate synthase n=1 Tax=Methylobacterium extorquens PA1
RepID=A9W659_METEP
Length = 520
Score = 86.7 bits (213), Expect = 7e-16
Identities = 53/138 (38%), Positives = 80/138 (57%), Gaps = 1/138 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG L D Q ++F RFKA+A++KK V D D+ ALV ++ KL+ + + GT
Sbjct: 350 ELGISLSDNQFQDVFERFKALADRKKHVYDEDIEALVDEKRATAHDRIKLVSLSVIAGTR 409
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T+K+ + DG+ A + G GPVDA + A+ IV A L Y ++AVTEG DA A
Sbjct: 410 GPQRATMKI-EMDGRIFTAEADGNGPVDAVFNAIHEIVPHDAVLELYQVHAVTEGTDAQA 468
Query: 365 TTRVLIR-GDNNYSSTNA 415
V ++ G+ + ++ A
Sbjct: 469 EVSVRLKAGERSVTARGA 486
[191][TOP]
>UniRef100_C7C7H0 2-isopropylmalate synthase n=2 Tax=Methylobacterium extorquens
RepID=C7C7H0_METED
Length = 520
Score = 86.7 bits (213), Expect = 7e-16
Identities = 53/138 (38%), Positives = 80/138 (57%), Gaps = 1/138 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG L D Q ++F RFKA+A++KK V D D+ ALV ++ KL+ + + GT
Sbjct: 350 ELGISLSDNQFQDVFERFKALADRKKHVYDEDIEALVDEKRATAHDRIKLVSLSVIAGTR 409
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T+K+ + DG+ A + G GPVDA + A+ IV A L Y ++AVTEG DA A
Sbjct: 410 GPQRATMKI-EMDGRIFTAEADGNGPVDAVFNAIHEIVPHDAVLELYQVHAVTEGTDAQA 468
Query: 365 TTRVLIR-GDNNYSSTNA 415
V ++ G+ + ++ A
Sbjct: 469 EVSVRLKAGERSVTARGA 486
[192][TOP]
>UniRef100_C6QIH1 2-isopropylmalate synthase n=1 Tax=Hyphomicrobium denitrificans
ATCC 51888 RepID=C6QIH1_9RHIZ
Length = 526
Score = 86.7 bits (213), Expect = 7e-16
Identities = 51/129 (39%), Positives = 74/129 (57%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L D + + F RFKA+A++KK V D D+ ALV D V K+ + + GT+
Sbjct: 357 ELGYNLGDNAMEDAFNRFKALADRKKHVYDEDIEALVDDGVAHMNDRVKVAALTVIAGTM 416
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G ++T+ L D +G+ +VG GPVDA + A+ ++ A L Y ++AVTEG DA A
Sbjct: 417 GPQSATLTL-DIEGQSKTVQAVGNGPVDATFNAIKQLLPHNARLDLYQVHAVTEGTDAQA 475
Query: 365 TTRVLIRGD 391
V + D
Sbjct: 476 EVSVRLEED 484
[193][TOP]
>UniRef100_Q138Z2 2-isopropylmalate synthase n=1 Tax=Rhodopseudomonas palustris BisB5
RepID=LEU1_RHOPS
Length = 524
Score = 86.7 bits (213), Expect = 7e-16
Identities = 49/137 (35%), Positives = 78/137 (56%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L Q+ ++F RFKA+A++KK V D D+ ALV +++ + + +L + + GT
Sbjct: 350 ELGYKLSRNQIEDVFVRFKALADRKKDVYDEDIEALVDEQLLHGQDLIRLKSLTVIAGTH 409
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T+K+ D DG+ + + G GPVDA + + +V A L Y ++AVTEG DA A
Sbjct: 410 GPQRATMKI-DVDGQLRIEEAEGNGPVDAVFNCIKALVPHDAKLELYQVHAVTEGTDAQA 468
Query: 365 TTRVLIRGDNNYSSTNA 415
V + + + A
Sbjct: 469 EVSVRLSHEGRSMTARA 485
[194][TOP]
>UniRef100_B8J4F8 2-isopropylmalate synthase n=1 Tax=Desulfovibrio desulfuricans
subsp. desulfuricans str. ATCC 27774 RepID=B8J4F8_DESDA
Length = 515
Score = 86.3 bits (212), Expect = 1e-15
Identities = 49/139 (35%), Positives = 79/139 (56%), Gaps = 1/139 (0%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQI-TCGTL 184
+GY LDD QL+ +F K +A++KK + D DL+ALV +E+++ ++L + + + T
Sbjct: 344 MGYKLDDDQLNLIFEAVKQLADRKKNLHDDDLMALVQEEIYRAPDRFRLRHVSVQSSDTG 403
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G+ + + D DGKE G GPVDA + + +V A L +Y++NA+T G DA+
Sbjct: 404 GVPPTAAVIMDVDGKESSGAGFGVGPVDALFNVIADMVGREAELEQYAINAITGGTDALG 463
Query: 365 TTRVLIRGDNNYSSTNAVT 421
V +R D YS+ T
Sbjct: 464 EVTVRLR-DGEYSAVGRGT 481
[195][TOP]
>UniRef100_A1B9A2 2-isopropylmalate synthase n=1 Tax=Paracoccus denitrificans PD1222
RepID=A1B9A2_PARDP
Length = 520
Score = 86.3 bits (212), Expect = 1e-15
Identities = 54/138 (39%), Positives = 76/138 (55%), Gaps = 1/138 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPE-AVWKLLDMQITCGT 181
+LGY L D QL ++F RFKA+A++KK V D DL+ALV D E ++ +++ CG+
Sbjct: 344 DLGYELGDNQLKDVFIRFKALADRKKEVYDDDLVALVQDAATNTEDDHLQVKHLRVVCGS 403
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
G S L G+E + G GPVDA + AV I A L Y ++AVTEG DA
Sbjct: 404 DGQSADLTMLV--GGEEQTVHAEGDGPVDACFNAVKAIWPHRARLQLYQVHAVTEGTDAQ 461
Query: 362 ATTRVLIRGDNNYSSTNA 415
AT V + + ++ A
Sbjct: 462 ATVSVRMEEEGRIATGQA 479
[196][TOP]
>UniRef100_Q2CGZ5 2-isopropylmalate synthase n=1 Tax=Oceanicola granulosus HTCC2516
RepID=Q2CGZ5_9RHOB
Length = 521
Score = 86.3 bits (212), Expect = 1e-15
Identities = 50/134 (37%), Positives = 80/134 (59%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LG+ L D QL+++F RFK +A++KK V D DL+ALV ++V +L+ +++ CGT
Sbjct: 344 DLGFDLADNQLNDVFVRFKDLADRKKEVYDEDLVALVRQNEGAEDSV-RLVSLRVVCGTG 402
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G + + + L + DG E + G GPVD+A+ A+ + L Y ++AVTEG DA A
Sbjct: 403 GPAEAEMVL-EVDGAEKSGTARGDGPVDSAFNAIKALYPHDVRLPLYQVHAVTEGTDAQA 461
Query: 365 TTRVLIRGDNNYSS 406
T V + D ++
Sbjct: 462 TVTVRLEEDGRIAT 475
[197][TOP]
>UniRef100_C2LWA8 2-isopropylmalate synthase n=1 Tax=Staphylococcus hominis SK119
RepID=C2LWA8_STAHO
Length = 510
Score = 86.3 bits (212), Expect = 1e-15
Identities = 46/131 (35%), Positives = 79/131 (60%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY ++ Q LF +FKAVA++KK V+D D+ A++ + A++++ +Q+ + G
Sbjct: 344 LGYDIEPKQQIELFKQFKAVADKKKSVSDRDIHAMIQGSEHEQNAIYQVETLQLQYVSNG 403
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
L ++ V + D G + S+GTG + A Y AVD I K+ + L++Y +++VTEG DA A
Sbjct: 404 LQSAVVVIKDKKGHIYQDSSIGTGSIVAIYNAVDSIFKKDSELIDYRIDSVTEGTDAQAE 463
Query: 368 TRVLIRGDNNY 400
V + +N +
Sbjct: 464 VHVELVIENQH 474
[198][TOP]
>UniRef100_A9HS14 2-isopropylmalate synthase n=1 Tax=Roseobacter litoralis Och 149
RepID=A9HS14_9RHOB
Length = 522
Score = 86.3 bits (212), Expect = 1e-15
Identities = 50/128 (39%), Positives = 73/128 (57%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LG+ L D QL ++F RFK +A++KK + D DLIAL+ +L+ +++ CGT G
Sbjct: 348 LGFELGDNQLKDVFVRFKELADRKKEIYDDDLIALMRTATDPENDRIQLVSLRVVCGTDG 407
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
+ + L + DG E G GPVDA++ A+ +V A L Y ++AVTEG DA AT
Sbjct: 408 PQQADLVL-NIDGVEESTTQTGDGPVDASFNAIKALVAHSARLQLYQVHAVTEGTDAQAT 466
Query: 368 TRVLIRGD 391
V + D
Sbjct: 467 VSVRMEED 474
[199][TOP]
>UniRef100_Q3AEQ5 2-isopropylmalate synthase n=1 Tax=Carboxydothermus
hydrogenoformans Z-2901 RepID=LEU1_CARHZ
Length = 509
Score = 86.3 bits (212), Expect = 1e-15
Identities = 50/127 (39%), Positives = 77/127 (60%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L + QL+ F +FKA+A++KK VTD DL A++ +E+ + + L I+ G+
Sbjct: 342 ELGYELTEEQLNEAFVKFKALADKKKEVTDQDLEAMMEEEIRKVPETYTLDYFHISTGST 401
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
+ T+TV L +G++ + G GPVDA YKA++ I L +YS+NAVT G DA+
Sbjct: 402 IIPTATVGLI-KEGEKLEDAATGDGPVDAIYKAINKITGLTPVLEQYSINAVTSGEDALG 460
Query: 365 TTRVLIR 385
V ++
Sbjct: 461 EVVVKLK 467
[200][TOP]
>UniRef100_Q67KX4 2-isopropylmalate synthase n=1 Tax=Symbiobacterium thermophilum
RepID=Q67KX4_SYMTH
Length = 523
Score = 85.9 bits (211), Expect = 1e-15
Identities = 48/135 (35%), Positives = 77/135 (57%), Gaps = 2/135 (1%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEA--VWKLLDMQITCGT 181
LGY L D ++ + F RFK +A++K+ +TD DL+A+V DE V +L Q+ G
Sbjct: 344 LGYQLTDAEIDSAFRRFKELADRKRTITDHDLMAIVGDEQAHRTVTEVCRLESFQVVAGN 403
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
++T++V+L +G+ + G GP+ A Y A+D + LL+Y +NAVTEG DA+
Sbjct: 404 ERIATASVRLV-REGEVVQEAASGDGPISALYHAIDRAARFEGQLLDYRLNAVTEGEDAL 462
Query: 362 ATTRVLIRGDNNYSS 406
V +R + +S
Sbjct: 463 GEVTVRVRAGDRVAS 477
[201][TOP]
>UniRef100_C6PQI3 2-isopropylmalate synthase n=1 Tax=Clostridium carboxidivorans P7
RepID=C6PQI3_9CLOT
Length = 514
Score = 85.9 bits (211), Expect = 1e-15
Identities = 54/140 (38%), Positives = 78/140 (55%), Gaps = 1/140 (0%)
Frame = +2
Query: 5 ELGYV-LDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGT 181
ELGY L +++ F +FK +A++KK V+D D+ ALV E FQ ++KL QI+ G
Sbjct: 343 ELGYANLSMDKINEAFIKFKDLADKKKSVSDEDIEALVIQEAFQIPELFKLEYFQISSGN 402
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
L+TSTVKL D K A S+G GPVDA +KA++ + L Y + A+ G DA+
Sbjct: 403 STLATSTVKLGFEDKKLEEA-SLGDGPVDATFKAIEKAIGIDVILKNYFLKAIGSGKDAL 461
Query: 362 ATTRVLIRGDNNYSSTNAVT 421
+ I DN S ++
Sbjct: 462 GEVTLKIEKDNRIYSGKGIS 481
[202][TOP]
>UniRef100_B6AN22 2-isopropylmalate synthase AA and pyruvate n=1 Tax=Leptospirillum
sp. Group II '5-way CG' RepID=B6AN22_9BACT
Length = 532
Score = 85.9 bits (211), Expect = 1e-15
Identities = 50/128 (39%), Positives = 72/128 (56%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
+GY LD + +F RFK +A+QKK + + DL L+++E Q + L + ++ GT
Sbjct: 351 MGYSLDGEEFERVFSRFKKLADQKKELYEEDLEVLLTEEESQTRDRFVLKRLHVSGGTEI 410
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
T+TV L + DG EH +G GPVDA Y+ V I A L+ YS+ A+T G DA+
Sbjct: 411 PPTATVVL-ERDGVEHRMAGLGDGPVDAIYRTVSKITATNARLVSYSVKAITGGTDALGE 469
Query: 368 TRVLIRGD 391
V I GD
Sbjct: 470 VTVRIEGD 477
[203][TOP]
>UniRef100_A3SVG7 2-Isopropylmalate synthase n=1 Tax=Sulfitobacter sp. NAS-14.1
RepID=A3SVG7_9RHOB
Length = 523
Score = 85.9 bits (211), Expect = 1e-15
Identities = 51/128 (39%), Positives = 70/128 (54%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY L D QL ++F RFK +A++KK + D DLIAL+ L M + CGT G
Sbjct: 348 LGYELGDNQLKDVFVRFKELADRKKEIYDDDLIALMRTATDPESDRIVLNSMTVVCGTEG 407
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
+ + L+ DG E G GPVDA++ + +V+ A L Y ++AVTEG DA AT
Sbjct: 408 PQKAEMSLS-VDGTETSTSQTGDGPVDASFNCIKALVEHTARLQLYQVHAVTEGTDAQAT 466
Query: 368 TRVLIRGD 391
V + D
Sbjct: 467 VSVRLEED 474
[204][TOP]
>UniRef100_A3EQC8 2-isopropylmalate synthase n=1 Tax=Leptospirillum rubarum
RepID=A3EQC8_9BACT
Length = 532
Score = 85.9 bits (211), Expect = 1e-15
Identities = 50/128 (39%), Positives = 72/128 (56%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
+GY LD + +F RFK +A+QKK + + DL L+++E Q + L + ++ GT
Sbjct: 351 MGYSLDGEEFERVFSRFKKLADQKKELYEEDLEVLLTEEESQTRDRFVLKRLHVSGGTEI 410
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
T+TV L + DG EH +G GPVDA Y+ V I A L+ YS+ A+T G DA+
Sbjct: 411 PPTATVVL-ERDGVEHRMAGLGDGPVDAIYRTVSKITATNARLVSYSVKAITGGTDALGE 469
Query: 368 TRVLIRGD 391
V I GD
Sbjct: 470 VTVRIEGD 477
[205][TOP]
>UniRef100_Q4L7U0 2-isopropylmalate synthase n=1 Tax=Staphylococcus haemolyticus
JCSC1435 RepID=LEU1_STAHJ
Length = 510
Score = 85.9 bits (211), Expect = 1e-15
Identities = 44/123 (35%), Positives = 75/123 (60%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY ++ + LF +FKA+A++KK VTD D+ A++ + A++++ +Q+ + G
Sbjct: 344 LGYDIEPQNQAELFKQFKAIADKKKSVTDRDIHAIIQGTEHEQNAIYQVDTLQLQFVSNG 403
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
L ++ V + D +G + S+GTG + A Y AVD I K + L++Y +++VTEG DA A
Sbjct: 404 LQSAVVVIKDKNGNIYQDSSIGTGSIVAIYNAVDRIFKHKSELIDYRIDSVTEGTDAQAE 463
Query: 368 TRV 376
V
Sbjct: 464 VHV 466
[206][TOP]
>UniRef100_B1ZDN3 2-isopropylmalate synthase n=1 Tax=Methylobacterium populi BJ001
RepID=LEU1_METPB
Length = 520
Score = 85.9 bits (211), Expect = 1e-15
Identities = 52/138 (37%), Positives = 79/138 (57%), Gaps = 1/138 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG L D Q ++F RFK +A++KK V D D+ ALV +++ KLL + + GT
Sbjct: 350 ELGISLSDNQFQDVFERFKDLADRKKHVYDEDIEALVDEKLATAHDRIKLLSLSVIAGTR 409
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T+K+ + DG+ + G GPVDA + A+ IV A L Y ++AVTEG DA A
Sbjct: 410 GPQRATMKI-EMDGRTFTEEADGNGPVDAVFNAIHEIVPHDAVLELYQVHAVTEGTDAQA 468
Query: 365 TTRVLIR-GDNNYSSTNA 415
V ++ G+ + ++ A
Sbjct: 469 EVSVRLKAGERSVTARGA 486
[207][TOP]
>UniRef100_C0QPV4 2-isopropylmalate synthase n=1 Tax=Persephonella marina EX-H1
RepID=C0QPV4_PERMH
Length = 514
Score = 85.5 bits (210), Expect = 2e-15
Identities = 47/127 (37%), Positives = 78/127 (61%), Gaps = 1/127 (0%)
Frame = +2
Query: 5 ELGYV-LDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGT 181
ELGY L + ++ LF +FKA+A++KK V D D+ AL+ DE+F+ KL+ + G
Sbjct: 343 ELGYRNLSEEEVDKLFRKFKALADKKKEVFDEDIEALIFDELFRTYEEVKLVYFHVLSGN 402
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
+ +STVK+ + DGKE A + G GP+D+A KA++ + L +YS+ +++ G DA+
Sbjct: 403 SAIPSSTVKI-EKDGKEITATACGDGPIDSALKAIEKALGMTGRLKDYSIRSLSAGKDAM 461
Query: 362 ATTRVLI 382
R ++
Sbjct: 462 GEVRTVV 468
[208][TOP]
>UniRef100_A3SGB0 2-Isopropylmalate synthase n=1 Tax=Sulfitobacter sp. EE-36
RepID=A3SGB0_9RHOB
Length = 523
Score = 85.5 bits (210), Expect = 2e-15
Identities = 52/128 (40%), Positives = 68/128 (53%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY L D QL ++F RFK +A++KK + D DLIAL+ L M + CGT G
Sbjct: 348 LGYELGDNQLKDVFVRFKELADRKKEIYDDDLIALMRTATDPESDRIVLGSMTVVCGTEG 407
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
+ + L DG E G GPVDAA+ + +V A L Y ++AVTEG DA AT
Sbjct: 408 PQKAEMSLT-VDGAETSTSQTGDGPVDAAFNCIKALVDHSARLQLYQVHAVTEGTDAQAT 466
Query: 368 TRVLIRGD 391
V + D
Sbjct: 467 VSVRLEED 474
[209][TOP]
>UniRef100_Q3A3A9 2-isopropylmalate synthase n=1 Tax=Pelobacter carbinolicus DSM 2380
RepID=Q3A3A9_PELCD
Length = 513
Score = 85.1 bits (209), Expect = 2e-15
Identities = 46/118 (38%), Positives = 69/118 (58%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L L F RFKA+A+QKK + D DL A+V+DE+ + +KL+ M + G+
Sbjct: 346 ELGYDLSKEDLDRAFTRFKALADQKKEIFDEDLDAIVADEIIRIPEKYKLVQMVTSSGSF 405
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDA 358
+TV + + DG+ A +G GPVDA +K + + A LL +++ A+T G DA
Sbjct: 406 AAPIATVAM-EIDGEIKKAAMMGGGPVDATFKTIKKLTDSKADLLSFTVGAITGGTDA 462
[210][TOP]
>UniRef100_Q2W1F9 Isopropylmalate/homocitrate/citramalate synthase n=1
Tax=Magnetospirillum magneticum AMB-1 RepID=Q2W1F9_MAGSA
Length = 544
Score = 85.1 bits (209), Expect = 2e-15
Identities = 48/129 (37%), Positives = 69/129 (53%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L D + + F RFK +A++KK V D D++ALV D V + KL+ +++ CGT
Sbjct: 374 ELGYELGDNAIEDAFTRFKDLADRKKDVFDEDIVALVDDAVVRGNDRVKLVSLEVLCGTK 433
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
S DG+ + G GPVDA + A+ + A L Y ++AVT+G DA A
Sbjct: 434 HQPPSATLELSVDGEVKGVRATGDGPVDATFNAIKALFPHEARLQLYQVSAVTQGTDAQA 493
Query: 365 TTRVLIRGD 391
V + D
Sbjct: 494 EVTVRLEED 502
[211][TOP]
>UniRef100_B2ULC1 2-isopropylmalate synthase n=1 Tax=Akkermansia muciniphila ATCC
BAA-835 RepID=B2ULC1_AKKM8
Length = 518
Score = 85.1 bits (209), Expect = 2e-15
Identities = 48/124 (38%), Positives = 71/124 (57%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LG+VL + +++ +F RFK V + KK V D DL A+V D + +W+L +Q G+
Sbjct: 345 QLGHVLTEEEVNTVFERFKKVGDSKKFVYDDDLSAIVDDSLHASTGLWELDFLQFVAGSH 404
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L +GK+ S G G VDA KA++ I + TL YS+NA +EG DA+
Sbjct: 405 ARPTATVGLL-KEGKKFEDSSTGNGAVDAVIKAIERITRRKGTLKGYSVNAASEGKDALG 463
Query: 365 TTRV 376
V
Sbjct: 464 EVTV 467
[212][TOP]
>UniRef100_B0UKW3 2-isopropylmalate synthase n=1 Tax=Methylobacterium sp. 4-46
RepID=B0UKW3_METS4
Length = 519
Score = 85.1 bits (209), Expect = 2e-15
Identities = 51/138 (36%), Positives = 79/138 (57%), Gaps = 1/138 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
E+GY L D Q + F RFKA+A++KK V D D+ ALV + + +L+ + + GT
Sbjct: 349 EMGYRLSDNQFQDAFERFKALADRKKNVYDEDIEALVDENLATAHDRIRLVSLTVIAGTR 408
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T++L D +G+ + G GPVDA + A+ +V A L Y ++AVTEG DA A
Sbjct: 409 GPQRATMRL-DIEGRLATEEADGNGPVDAVFNAIHALVPHEAKLELYDVHAVTEGTDAQA 467
Query: 365 TTRVLIR-GDNNYSSTNA 415
V +R G+ + ++ A
Sbjct: 468 EVSVRLRQGERSVTARGA 485
[213][TOP]
>UniRef100_A8LPL9 2-isopropylmalate synthase n=1 Tax=Dinoroseobacter shibae DFL 12
RepID=A8LPL9_DINSH
Length = 525
Score = 85.1 bits (209), Expect = 2e-15
Identities = 52/138 (37%), Positives = 77/138 (55%), Gaps = 1/138 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQP-EAVWKLLDMQITCGT 181
+LGY L D QL ++F RFKA+A++KK + D DL+AL+S+ P + +++ CGT
Sbjct: 347 DLGYELADNQLKDVFVRFKALADRKKEIYDEDLVALMSESSSDPARERLSVKFLRVICGT 406
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
++ + L+ DG + + G GPVDA + AV + A L Y ++AVTEG DA
Sbjct: 407 EAPQSADLTLS-IDGVDKQVTAQGDGPVDATFNAVKALFPHTARLQLYQVHAVTEGTDAQ 465
Query: 362 ATTRVLIRGDNNYSSTNA 415
AT V + D S A
Sbjct: 466 ATVTVRMEEDGRIVSGQA 483
[214][TOP]
>UniRef100_A3V1U0 2-isopropylmalate synthase n=1 Tax=Loktanella vestfoldensis SKA53
RepID=A3V1U0_9RHOB
Length = 518
Score = 85.1 bits (209), Expect = 2e-15
Identities = 53/134 (39%), Positives = 76/134 (56%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L D QL+++F RFK +A++KK V D DL+ALV + + KL +++ CGT
Sbjct: 343 ELGFDLADNQLNDVFVRFKDLADRKKEVFDDDLMALVYQNDSGEDRI-KLKSLRVICGTE 401
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G + + L D DG + + G GPVDA + AV + A L Y + AVTEG DA A
Sbjct: 402 GPQQADMVL-DIDGTDVKTSATGDGPVDATFNAVKALFPHGARLQLYQVQAVTEGTDAQA 460
Query: 365 TTRVLIRGDNNYSS 406
T V + D ++
Sbjct: 461 TVMVRLDEDGRIAT 474
[215][TOP]
>UniRef100_A5EP79 2-isopropylmalate synthase n=1 Tax=Bradyrhizobium sp. BTAi1
RepID=LEU1_BRASB
Length = 523
Score = 85.1 bits (209), Expect = 2e-15
Identities = 50/137 (36%), Positives = 74/137 (54%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
E+G+ L Q+ + F RFKA+A++KK + D D+ AL+ + + KLL + + GT
Sbjct: 350 EMGHKLAGNQVEDAFVRFKALADRKKHIYDEDIEALIDEGMVSAHDRIKLLSLSVIAGTR 409
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T+KL D DG + S G GPVDA + + +V A L Y ++AVTEG DA A
Sbjct: 410 GPQRATMKL-DVDGVTKIEESEGNGPVDAVFNCIKSLVPHEAKLELYQVHAVTEGTDAQA 468
Query: 365 TTRVLIRGDNNYSSTNA 415
V + D + A
Sbjct: 469 EVSVRLSQDGRSMTARA 485
[216][TOP]
>UniRef100_C8WI89 2-isopropylmalate synthase n=1 Tax=Eggerthella lenta DSM 2243
RepID=C8WI89_9ACTN
Length = 510
Score = 84.7 bits (208), Expect = 3e-15
Identities = 47/126 (37%), Positives = 74/126 (58%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY L+ L ++ F +A++KK V D DL +LV++ A++ L +Q++ G
Sbjct: 344 ELGYELEGEALDQVYEAFLNLADKKKEVYDEDLESLVNERDRNESALYALEGVQVSTGFP 403
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+TV L ++ + AC GTGP+DA YKAV+ IV+ L E+S+ +VT GIDA+
Sbjct: 404 LTPTATVTLRNAADQVVTACEYGTGPIDAVYKAVNKIVQVDNELTEFSVQSVTRGIDALG 463
Query: 365 TTRVLI 382
+ +
Sbjct: 464 EVTIRV 469
[217][TOP]
>UniRef100_B9CVH3 2-isopropylmalate synthase n=1 Tax=Staphylococcus capitis SK14
RepID=B9CVH3_STACP
Length = 511
Score = 84.7 bits (208), Expect = 3e-15
Identities = 42/123 (34%), Positives = 74/123 (60%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY + NLF +FK VA++KK V+D D+ A++ + A+++L ++Q+ + G
Sbjct: 344 LGYDISTEDQINLFKQFKEVADKKKSVSDRDIHAIIRGSEHEQRAIYQLENLQLQYVSKG 403
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
L ++ V + D +GK + S+GTG + + Y A+D I + L++Y ++++TEG DA A
Sbjct: 404 LQSAVVVIKDKNGKTYQDSSIGTGSIVSIYNAIDRIFQRKTELIDYRIDSITEGADAQAE 463
Query: 368 TRV 376
V
Sbjct: 464 VHV 466
[218][TOP]
>UniRef100_B6AXP6 2-isopropylmalate synthase n=1 Tax=Rhodobacterales bacterium
HTCC2083 RepID=B6AXP6_9RHOB
Length = 529
Score = 84.7 bits (208), Expect = 3e-15
Identities = 48/123 (39%), Positives = 70/123 (56%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LG+ L D QL ++F RFK +A++KK + D DL+AL++ KL +++ CGT G
Sbjct: 353 LGFELGDNQLKDVFVRFKELADRKKEIFDDDLVALMNTASDPESERLKLTSLRVVCGTDG 412
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
+ +++ DG E + G GPVDA + AV + A L Y ++AVTEG DA AT
Sbjct: 413 PQEAVMRML-VDGVEKSTTATGDGPVDATFNAVKALFAHEARLQLYQVHAVTEGTDAQAT 471
Query: 368 TRV 376
V
Sbjct: 472 VSV 474
[219][TOP]
>UniRef100_B8I1T7 2-isopropylmalate synthase n=1 Tax=Clostridium cellulolyticum H10
RepID=LEU1_CLOCE
Length = 508
Score = 84.7 bits (208), Expect = 3e-15
Identities = 51/131 (38%), Positives = 75/131 (57%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
E+GY L D ++ F +FK +A++KK VTD D+ ALV + + PE ++ + QI G
Sbjct: 343 EMGYSLSDEEVKTAFAKFKDLADKKKVVTDKDIEALVDENIAVPE-IFVIDSFQINSGNK 401
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
+STSTV + D + + G GPVDAA+ AV+ A L+ Y + AVTEG DA+
Sbjct: 402 MISTSTVSVR-KDEEIITEAATGDGPVDAAFNAVERATGVNAELVHYRIKAVTEGKDALG 460
Query: 365 TTRVLIRGDNN 397
V I +N+
Sbjct: 461 EVTVKISNNNS 471
[220][TOP]
>UniRef100_Q89GB0 2-isopropylmalate synthase n=1 Tax=Bradyrhizobium japonicum
RepID=LEU1_BRAJA
Length = 520
Score = 84.7 bits (208), Expect = 3e-15
Identities = 51/137 (37%), Positives = 74/137 (54%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
E+GY L QL + F R KA+A++KK + D D+ ALV +E+ KL + + GT
Sbjct: 350 EMGYKLGPNQLEDAFTRMKALADRKKDIYDEDIEALVDEEMAASHDRIKLTSLTVIAGTH 409
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T+KL D DG+ + + G GPVDA + + +V A L Y ++AVTEG DA A
Sbjct: 410 GPQRATMKL-DVDGQIKIEEAEGNGPVDAVFNCIKRLVPHEAKLELYQVHAVTEGTDAQA 468
Query: 365 TTRVLIRGDNNYSSTNA 415
V + D + A
Sbjct: 469 EVSVRLSHDGRSMTARA 485
[221][TOP]
>UniRef100_C0R089 2-isopropylmalate synthase n=1 Tax=Brachyspira hyodysenteriae WA1
RepID=C0R089_BRAHW
Length = 498
Score = 84.3 bits (207), Expect = 4e-15
Identities = 49/138 (35%), Positives = 73/138 (52%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY +DD L + F FKA+A++KK VTD+D+ AL+ ++ L + G
Sbjct: 343 LGYDIDDKALEDKFIEFKALADKKKIVTDSDIEALLIGNNDSDNPIYTLNGFVVNDGNSI 402
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
S +TV + D+ G GP+DAA+ A+D I A L+ YS+NA+TEG DA+
Sbjct: 403 SSLATVSIMDNQNNVVEGIGKGNGPIDAAFGAIDSITSNKAKLVNYSINAITEGEDALGE 462
Query: 368 TRVLIRGDNNYSSTNAVT 421
V + D+ AV+
Sbjct: 463 VIVKLASDDKTVIGRAVS 480
[222][TOP]
>UniRef100_C5QLP3 2-isopropylmalate synthase n=1 Tax=Staphylococcus epidermidis
M23864:W1 RepID=C5QLP3_STAEP
Length = 510
Score = 84.3 bits (207), Expect = 4e-15
Identities = 44/123 (35%), Positives = 74/123 (60%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY + LF +FK VA++KK V+D D+ A++ + A+++L ++Q+ + G
Sbjct: 344 LGYDISPEDQIALFKQFKEVADKKKAVSDRDIHAIIQGSEHEQNAIYQLENLQLQYVSKG 403
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
L ++ V + D++G+ + S+GTG + A Y AVD I K L++Y +++VTEG DA A
Sbjct: 404 LQSAVVVIKDNNGQTYQDSSIGTGSIVAIYNAVDRIFKRQTELIDYRIDSVTEGTDAQAE 463
Query: 368 TRV 376
V
Sbjct: 464 VHV 466
[223][TOP]
>UniRef100_A4IRH8 2-isopropylmalate synthase n=2 Tax=Geobacillus RepID=LEU1_GEOTN
Length = 515
Score = 84.3 bits (207), Expect = 4e-15
Identities = 48/128 (37%), Positives = 74/128 (57%), Gaps = 1/128 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQP-EAVWKLLDMQITCGT 181
ELGY L + +++ LF RFK +A++KK VTD DLIAL+ +E F + ++L +Q+ GT
Sbjct: 342 ELGYTLSEEEINQLFVRFKELADKKKDVTDDDLIALIFEEKFDHFKDFYQLSSIQVQYGT 401
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
+ T+ V L D G + G G V+A Y ++ + TLL+Y + +V G DA+
Sbjct: 402 NQIPTAVVVLKDGKGNTIQEAATGAGSVEALYNTLERCFQTAVTLLDYRIESVGGGRDAL 461
Query: 362 ATTRVLIR 385
A V +R
Sbjct: 462 AQVFVKVR 469
[224][TOP]
>UniRef100_C0Z9C8 2-isopropylmalate synthase n=1 Tax=Brevibacillus brevis NBRC 100599
RepID=LEU1_BREBN
Length = 512
Score = 84.0 bits (206), Expect = 5e-15
Identities = 41/130 (31%), Positives = 77/130 (59%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LGY L+ +++ F FK + ++KK +TD D++ALV ++ + ++L +Q+ G +
Sbjct: 342 DLGYHLEQEEVNAAFAAFKVLCDKKKEITDDDILALVDSKMVRGPEAFQLESVQLAYGNI 401
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
+ T++V+L +DG + G G VD+ YKA+D E +L++Y + +VT G DA+
Sbjct: 402 SVPTASVRLVRADGSVCEEAACGNGSVDSIYKAIDRATGEEVSLVDYKILSVTHGQDALG 461
Query: 365 TTRVLIRGDN 394
V ++ D+
Sbjct: 462 EVFVRLQQDD 471
[225][TOP]
>UniRef100_A6DDK1 2-ISOPROPYLMALATE SYNTHASE n=1 Tax=Caminibacter mediatlanticus TB-2
RepID=A6DDK1_9PROT
Length = 515
Score = 83.6 bits (205), Expect = 6e-15
Identities = 42/130 (32%), Positives = 79/130 (60%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LG+ + + +L+ +F +FK +A++KK + D D++A++ D + V++L+ +Q++ + G
Sbjct: 342 LGFEVSEDELNEIFTKFKKLADKKKEIYDEDILAIMYDSTDKTPKVYELVSLQLSDCSDG 401
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
L ++ K+ D KE + +VG G +DA +K +D I L++Y + AV+EG DA+A
Sbjct: 402 LPSAAAKIRYED-KEFIDAAVGEGTIDAVFKVIDRISGISGKLMDYKVEAVSEGKDALAK 460
Query: 368 TRVLIRGDNN 397
V + D N
Sbjct: 461 VMVKVIFDEN 470
[226][TOP]
>UniRef100_A3TTT5 2-isopropylmalate synthase n=1 Tax=Oceanicola batsensis HTCC2597
RepID=A3TTT5_9RHOB
Length = 523
Score = 83.6 bits (205), Expect = 6e-15
Identities = 54/128 (42%), Positives = 72/128 (56%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LG L QL+++F RFK +A++KK V + DL LV D + +L D+++ CGT G
Sbjct: 348 LGIDLGQNQLNDVFVRFKDLADRKKEVYEDDLWTLVRDAEDETPDRLELKDLKVICGTGG 407
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
S V L DGKE A + G GPVDA + AV I A L Y ++AVT+G DA AT
Sbjct: 408 QSAEMVMLV--DGKETRAETSGDGPVDACFNAVKEIFPHQAKLELYQVHAVTQGTDAQAT 465
Query: 368 TRVLIRGD 391
V + D
Sbjct: 466 VSVRLNED 473
[227][TOP]
>UniRef100_B9XB18 2-isopropylmalate synthase n=1 Tax=bacterium Ellin514
RepID=B9XB18_9BACT
Length = 524
Score = 83.2 bits (204), Expect = 8e-15
Identities = 47/145 (32%), Positives = 77/145 (53%), Gaps = 6/145 (4%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LG+ +++ + +F RFK + ++KK V D DL ALV ++ + W L + +T G+
Sbjct: 349 LGFKMNEADVQAIFARFKEIGDKKKFVYDDDLAALVEGQITEVPETWSLEYLNVTSGSQT 408
Query: 188 LSTSTVKLADSDGKEH------VACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEG 349
+ T+TV+L K+ +G GPVDA KA+D + K L++YS+ AV++G
Sbjct: 409 VPTATVRLKRVSKKDKGEPEVLQDAGIGDGPVDATLKAIDRLAKTRGRLMDYSLRAVSQG 468
Query: 350 IDAIATTRVLIRGDNNYSSTNAVTG 424
DA+ V + N+ VTG
Sbjct: 469 KDALGEVTVKV----NFDGGELVTG 489
[228][TOP]
>UniRef100_B6WXT0 Putative uncharacterized protein n=1 Tax=Desulfovibrio piger ATCC
29098 RepID=B6WXT0_9DELT
Length = 515
Score = 83.2 bits (204), Expect = 8e-15
Identities = 49/128 (38%), Positives = 75/128 (58%), Gaps = 2/128 (1%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL- 184
LGY LDD QL +F KA+A++KK + D DL+ALV +EV++ +++L + +
Sbjct: 344 LGYSLDDDQLQIVFEAVKALADRKKTLHDDDLMALVQEEVYRMPDLYRLRHVSVQSSDAG 403
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAV-DLIVKEPATLLEYSMNAVTEGIDAI 361
G+ + L D DG E G GPVDA + + D++ +EP L +Y++NAVT G DA+
Sbjct: 404 GVPPTAAVLMDVDGMEKSGAGFGVGPVDAIFNVINDMLGREP-QLEQYAVNAVTGGTDAL 462
Query: 362 ATTRVLIR 385
V +R
Sbjct: 463 GEVTVRLR 470
[229][TOP]
>UniRef100_A4U0T7 2-isopropylmalate synthase n=1 Tax=Magnetospirillum gryphiswaldense
RepID=A4U0T7_9PROT
Length = 514
Score = 83.2 bits (204), Expect = 8e-15
Identities = 46/129 (35%), Positives = 69/129 (53%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LGY L D + + F RFK VA++KK V D D++ALV + VF+ + +++ CGT
Sbjct: 344 QLGYDLGDNAIEDAFARFKDVADRKKEVFDEDIVALVDEAVFRDNERIRFKGLEVLCGTR 403
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
+ DG+ + G GPVDA + A+ + A LL Y ++AVT+G DA A
Sbjct: 404 HNPPKAELELEIDGELKSVKATGDGPVDATFNAIKALCPHEARLLLYQVHAVTQGTDAQA 463
Query: 365 TTRVLIRGD 391
V + D
Sbjct: 464 EVTVRLEED 472
[230][TOP]
>UniRef100_B1I1Y1 2-isopropylmalate synthase n=1 Tax=Candidatus Desulforudis
audaxviator MP104C RepID=LEU1_DESAP
Length = 509
Score = 83.2 bits (204), Expect = 8e-15
Identities = 47/132 (35%), Positives = 77/132 (58%), Gaps = 1/132 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L + +L+ F RFK +A+ KK++TD DL A++ + + Q A ++L + + GT
Sbjct: 343 ELGFELHEEELNRAFVRFKELADSKKQITDEDLEAILDETIRQVPATYELDYLHVFSGTT 402
Query: 185 GLSTSTV-KLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
T+ + L D + AC G GPVDA YKA++ +L+ Y ++AVT G DA+
Sbjct: 403 VKPTAVIGLLIDGQFVQEAAC--GNGPVDATYKAIEKATGRKYSLVSYVIDAVTGGTDAL 460
Query: 362 ATTRVLIRGDNN 397
A + +R D++
Sbjct: 461 ANVTLKMRDDDH 472
[231][TOP]
>UniRef100_D0D9X1 2-isopropylmalate synthase n=1 Tax=Citreicella sp. SE45
RepID=D0D9X1_9RHOB
Length = 522
Score = 82.8 bits (203), Expect = 1e-14
Identities = 48/135 (35%), Positives = 80/135 (59%), Gaps = 1/135 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVF-QPEAVWKLLDMQITCGT 181
+LG + D QL ++F RFK +A++KK V D D++ALV+ + + +++ +++ CGT
Sbjct: 346 DLGVEVGDNQLKDIFVRFKDLADRKKEVFDEDILALVTAAMTTEGTDHLEIVSLKVICGT 405
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
G + + +++ + G+E A G GPVDA +KAV + A L Y ++AVTEG DA
Sbjct: 406 AGQAEAVLEM-EVGGEERSADEYGDGPVDATFKAVRKLYPNKARLQLYQVHAVTEGTDAQ 464
Query: 362 ATTRVLIRGDNNYSS 406
AT V + D ++
Sbjct: 465 ATVSVRLEEDGKIAT 479
[232][TOP]
>UniRef100_B9R0E4 2-isopropylmalate synthase n=1 Tax=Labrenzia alexandrii DFL-11
RepID=B9R0E4_9RHOB
Length = 518
Score = 82.8 bits (203), Expect = 1e-14
Identities = 50/134 (37%), Positives = 73/134 (54%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELG+ L D L + F RFK +A++KK V D D+ ALV DE+ K++ + + GT
Sbjct: 348 ELGFELGDNALQDAFRRFKDLADRKKHVYDEDIEALVEDEINILGESTKVIALTVIAGTG 407
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G + + + D DG+ + G GPVDA + A+ I ATL Y ++AVTEG DA A
Sbjct: 408 GPQKAILTM-DVDGQHVTKEATGDGPVDATFNAIKAISPHEATLSLYQVHAVTEGTDAQA 466
Query: 365 TTRVLIRGDNNYSS 406
V + D ++
Sbjct: 467 EVSVRLEADGRIAT 480
[233][TOP]
>UniRef100_Q8RL85 2-isopropylmalate synthase n=1 Tax=Geobacillus stearothermophilus
RepID=LEU1_BACST
Length = 515
Score = 82.8 bits (203), Expect = 1e-14
Identities = 48/128 (37%), Positives = 74/128 (57%), Gaps = 1/128 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQP-EAVWKLLDMQITCGT 181
ELGY L D +++ LF RFK +A++KK +TD DLIAL+ +E F + ++L +Q+ GT
Sbjct: 342 ELGYTLSDEEINQLFVRFKELADKKKDITDDDLIALIFEEKFDHFKDFYQLSSIQVQYGT 401
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
+ T+ V L G E + G+G V A Y ++ + TLL+Y + +V G DA+
Sbjct: 402 NQIPTAVVVLKYGKGNEIQEAATGSGSVYALYNTLERCFQTEVTLLDYRIESVGGGRDAL 461
Query: 362 ATTRVLIR 385
A V +R
Sbjct: 462 AQVFVKVR 469
[234][TOP]
>UniRef100_B6R018 2-isopropylmalate synthase n=1 Tax=Pseudovibrio sp. JE062
RepID=B6R018_9RHOB
Length = 518
Score = 82.4 bits (202), Expect = 1e-14
Identities = 51/136 (37%), Positives = 74/136 (54%)
Frame = +2
Query: 2 NELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGT 181
+ELGY L D L F RFK +A++KK V D D+ ALV D++ K++ + + GT
Sbjct: 346 SELGYELGDNALQEAFRRFKDLADRKKNVYDEDIEALVEDQITIESESVKVIALTVIAGT 405
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
G + + + D +GK + G GPVDA + A+ I AT+ Y ++AVTEG DA
Sbjct: 406 GGPQKAILTM-DVNGKHETREATGDGPVDATFNAIKAIWPHDATMSLYQVHAVTEGTDAQ 464
Query: 362 ATTRVLIRGDNNYSST 409
A V + DN +T
Sbjct: 465 AEVSVRLE-DNGKIAT 479
[235][TOP]
>UniRef100_Q3SHE7 2-isopropylmalate synthase n=1 Tax=Thiobacillus denitrificans ATCC
25259 RepID=LEU1_THIDA
Length = 511
Score = 82.4 bits (202), Expect = 1e-14
Identities = 54/131 (41%), Positives = 73/131 (55%), Gaps = 2/131 (1%)
Frame = +2
Query: 5 ELGYVLDDGQLSNL-FWRFKAVAEQKKRVTDADLIALVSDEVFQPEAV-WKLLDMQITCG 178
ELG VLD + N F RFK +A++K+ + D DL ALVSDE + E +KLL M++ C
Sbjct: 343 ELGIVLDSEEALNAAFARFKDLADKKREIFDEDLQALVSDEGYATEDERFKLLSMKV-CS 401
Query: 179 TLGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDA 358
G + DG E A G+GPVDA +KA++ +V A LL YS+N +T G DA
Sbjct: 402 ETGEVPRAQLVFTDDGAEKQASGEGSGPVDATFKALESVVHSGADLLLYSVNNITSGTDA 461
Query: 359 IATTRVLIRGD 391
V + D
Sbjct: 462 QGEVTVRLAQD 472
[236][TOP]
>UniRef100_B8DM91 2-isopropylmalate synthase n=1 Tax=Desulfovibrio vulgaris str.
'Miyazaki F' RepID=LEU1_DESVM
Length = 514
Score = 82.4 bits (202), Expect = 1e-14
Identities = 42/128 (32%), Positives = 72/128 (56%)
Frame = +2
Query: 2 NELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGT 181
+ELGY L++ QL +F K +A++KK++ D D+ ALV +EV++ +++L+++ + C
Sbjct: 345 DELGYRLEEAQLVTVFEAVKKLADKKKQIYDEDIEALVLEEVYRLPDLYRLVNLSVQCSD 404
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
G+ + + D G+ A G GP+DA + + IV L YS+ A+T G DA
Sbjct: 405 TGMPPTAAVVMDVMGEVKRAAGFGVGPIDAVFNVIGEIVGRAPVLERYSVTAITGGTDAQ 464
Query: 362 ATTRVLIR 385
V +R
Sbjct: 465 GEVTVRLR 472
[237][TOP]
>UniRef100_Q0C523 2-isopropylmalate synthase n=1 Tax=Hyphomonas neptunium ATCC 15444
RepID=Q0C523_HYPNA
Length = 519
Score = 82.0 bits (201), Expect = 2e-14
Identities = 47/129 (36%), Positives = 74/129 (57%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
+GY ++ L++ F RFK +A++KK V D D+IALV +++ +++ GT G
Sbjct: 355 MGYFIEGDALNDAFKRFKDLADRKKHVFDDDIIALVDEQLAAEGERIAFKRLRVVAGTEG 414
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIAT 367
T+ + L DG+E + + G GPVDA + A+ +V A L Y ++AVT G DA AT
Sbjct: 415 PQTAEIDLV-IDGEEKYSIARGNGPVDAVFNAIRQLVPHQAILELYQVHAVTGGTDAQAT 473
Query: 368 TRVLIRGDN 394
V + GD+
Sbjct: 474 VSVRLNGDD 482
[238][TOP]
>UniRef100_Q1K340 2-isopropylmalate synthase n=1 Tax=Desulfuromonas acetoxidans DSM
684 RepID=Q1K340_DESAC
Length = 512
Score = 82.0 bits (201), Expect = 2e-14
Identities = 45/117 (38%), Positives = 69/117 (58%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTLG 187
LGY L + F RFKA+A+ KK + D DL A+V+DE+ + +KLL M ++ G+
Sbjct: 347 LGYDLSKEDIEKAFVRFKALADVKKEIFDEDLDAIVADEIIRVPERYKLLQMNVSSGSFA 406
Query: 188 LSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDA 358
T+TV++ + DG+ +G GPVDA +KA+ + LL +S+ A+T G DA
Sbjct: 407 APTATVQM-EVDGEICKTAVIGDGPVDATFKAIKDLSGCDVRLLHFSVGAITGGTDA 462
[239][TOP]
>UniRef100_C7ILY9 2-isopropylmalate synthase n=1 Tax=Clostridium papyrosolvens DSM
2782 RepID=C7ILY9_9CLOT
Length = 508
Score = 82.0 bits (201), Expect = 2e-14
Identities = 49/126 (38%), Positives = 72/126 (57%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
E+GY L D ++ F +FK +A++KK VTD D+ ALV + + PE ++ + QI G
Sbjct: 343 EMGYSLSDEEVKTAFAKFKDLADKKKVVTDKDIEALVDENIAVPE-IFVIDSFQINSGNK 401
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
+STSTV + D + + G GPVDAA+ A++ A L+ Y + AVTEG DA+
Sbjct: 402 MISTSTVSI-KKDEEIITEAATGDGPVDAAFNAIERATGVNAELVHYRIKAVTEGKDALG 460
Query: 365 TTRVLI 382
V I
Sbjct: 461 EVTVKI 466
[240][TOP]
>UniRef100_C2BZ04 2-isopropylmalate synthase n=1 Tax=Listeria grayi DSM 20601
RepID=C2BZ04_LISGR
Length = 512
Score = 82.0 bits (201), Expect = 2e-14
Identities = 44/130 (33%), Positives = 75/130 (57%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
ELGY + + S LF RFK +A+ KK+VT+ D+ ALV E + + ++L MQI T
Sbjct: 342 ELGYEITADEQSRLFKRFKQLADAKKQVTEEDIHALVLGESQEADKPFELEHMQIQYVTN 401
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G+ + +++ D+ GK + G+G ++A Y A++ + + TL +Y + +++ G DA A
Sbjct: 402 GIQAAVLRIKDATGKIAEDAATGSGSIEAIYNAINRLTNQTVTLSDYRIQSISAGQDAQA 461
Query: 365 TTRVLIRGDN 394
V+I N
Sbjct: 462 EVHVIIETTN 471
[241][TOP]
>UniRef100_C1SHN1 2-isopropylmalate synthase n=1 Tax=Denitrovibrio acetiphilus DSM
12809 RepID=C1SHN1_9BACT
Length = 519
Score = 82.0 bits (201), Expect = 2e-14
Identities = 41/118 (34%), Positives = 67/118 (56%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LGY +++ + + F FK +A++KK V D D+ +++ ++ + + + + I G
Sbjct: 345 DLGYEIENDAMQSAFDEFKILADKKKEVFDEDIESIIFNQAKDEQFAYVMESVNILSGDT 404
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDA 358
+ T+T+KLAD DG E V S G GPVDA KA++ I L Y + A+T G DA
Sbjct: 405 AIPTATIKLADKDGNEFVDASTGDGPVDAVMKAIERIAGVGGKLKSYQIKALTAGKDA 462
[242][TOP]
>UniRef100_A5D4W0 2-isopropylmalate synthase n=1 Tax=Pelotomaculum thermopropionicum
SI RepID=LEU1_PELTS
Length = 505
Score = 82.0 bits (201), Expect = 2e-14
Identities = 49/130 (37%), Positives = 73/130 (56%), Gaps = 1/130 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
E+GY L D +L++ F RFK +A++K +TD DL A++ +E+ + L + I+ GT
Sbjct: 343 EMGYNLSDEELNSAFERFKKLADKKMEITDEDLEAIIEEEMRLVPHTYTLEYLHISSGTT 402
Query: 185 GLSTSTVKL-ADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAI 361
+ T+TV L D E AC G GPVDA KA+D I T+ + +NAVT G DA+
Sbjct: 403 VVPTATVGLKRDGQLMEEAAC--GNGPVDAICKAIDKITGLNCTMTSWGINAVTAGKDAL 460
Query: 362 ATTRVLIRGD 391
+ + D
Sbjct: 461 GDVSLKVTAD 470
[243][TOP]
>UniRef100_B1M239 2-isopropylmalate synthase n=1 Tax=Methylobacterium radiotolerans
JCM 2831 RepID=B1M239_METRJ
Length = 521
Score = 81.6 bits (200), Expect = 2e-14
Identities = 49/138 (35%), Positives = 77/138 (55%), Gaps = 1/138 (0%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LG L D Q + F RFKA+A++KK V D D+ ALV + + +L+ + + GT
Sbjct: 351 DLGLHLSDNQFQDAFDRFKALADRKKHVYDEDIEALVDENLATAHDRIRLVSLSVIAGTR 410
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T+++AD G + + G GPVDA + A+ +V A L Y ++AVT G DA A
Sbjct: 411 GPQRATLRIADETG-TRIEEADGNGPVDAVFNAISALVPHQAQLELYQVHAVTGGTDAQA 469
Query: 365 TTRVLIR-GDNNYSSTNA 415
V +R G+ + ++ A
Sbjct: 470 EVSVRLRDGERSVTARGA 487
[244][TOP]
>UniRef100_Q0F2J9 2-isopropylmalate synthase n=1 Tax=Mariprofundus ferrooxydans PV-1
RepID=Q0F2J9_9PROT
Length = 514
Score = 81.6 bits (200), Expect = 2e-14
Identities = 48/118 (40%), Positives = 70/118 (59%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LG LD +L +F RFK +A++KK + D DL+AL+S + KL+ + GT
Sbjct: 344 QLGVELDGERLIEVFNRFKLLADKKKDIFDEDLMALLSGDGGVESERVKLVSLHTASGTS 403
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDA 358
+ V L D +G EH A + G GPVDAA+KA+ +V+ LL Y++NA+T G DA
Sbjct: 404 DAPVAAVVL-DIEGVEHKATAEGDGPVDAAFKAIQSLVEPNGKLLLYAVNAITAGTDA 460
[245][TOP]
>UniRef100_A3SI82 2-isopropylmalate synthase n=1 Tax=Roseovarius nubinhibens ISM
RepID=A3SI82_9RHOB
Length = 519
Score = 81.6 bits (200), Expect = 2e-14
Identities = 52/124 (41%), Positives = 76/124 (61%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LG + D QL ++F RFK +A++KK V D D++ALVS + +L+++++ CGT
Sbjct: 346 DLGIEVGDNQLKDIFVRFKDLADRKKEVYDDDILALVS-VTGETSNHLELINLKVICGT- 403
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G + + +++ D G+E A G GPVDA +KAV I A L Y +NAVTEG DA A
Sbjct: 404 GPAEAVLEM-DVGGEEKSATCQGDGPVDATFKAVREIWPNDAKLQLYQVNAVTEGTDAQA 462
Query: 365 TTRV 376
T V
Sbjct: 463 TVSV 466
[246][TOP]
>UniRef100_B8CX21 2-isopropylmalate synthase n=1 Tax=Halothermothrix orenii H 168
RepID=LEU1_HALOH
Length = 515
Score = 81.6 bits (200), Expect = 2e-14
Identities = 51/142 (35%), Positives = 82/142 (57%), Gaps = 3/142 (2%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LGY +DD +F FK +A++KK +T ++ AL+ + + V++L + + G
Sbjct: 342 KLGYDIDDETFEEIFIEFKKLADKKKNITHVEIEALIDNHYHTFDKVYELDYLSVNTGNK 401
Query: 185 GLSTSTVKLADSDGK-EHVACSVGTGPVDAAYKAVDLIVK-EPATLLEYSMNAVTEGIDA 358
L T+T+KL + E ACS G GPVDA ++A++ IV + L+ Y +NAVTEG DA
Sbjct: 402 VLPTATIKLKKENNIIEKAACS-GDGPVDAIFQAINEIVGIDDIKLISYHINAVTEGKDA 460
Query: 359 IATTRVLIR-GDNNYSSTNAVT 421
+ V + DN Y+ +A+T
Sbjct: 461 LGEVIVKTKIEDNTYTGHSAMT 482
[247][TOP]
>UniRef100_UPI0001788F2D 2-isopropylmalate synthase n=1 Tax=Geobacillus sp. Y412MC10
RepID=UPI0001788F2D
Length = 512
Score = 81.3 bits (199), Expect = 3e-14
Identities = 44/126 (34%), Positives = 72/126 (57%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LGY L + Q+++ F +FK +A++KK V+D DL+AL+ +++ V+KL + + G
Sbjct: 342 DLGYELTEEQVNDAFAKFKVLADKKKEVSDEDLLALLEEKLIDTPEVFKLETIFVAYGNE 401
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
T+ V++A D G G VDA Y A+D + E TL +YS+ +VT G DA
Sbjct: 402 STPTARVRIATEDQTIEEEAE-GNGSVDAIYNAIDKVTGEEVTLADYSIKSVTHGKDAQG 460
Query: 365 TTRVLI 382
V++
Sbjct: 461 EVHVVL 466
[248][TOP]
>UniRef100_Q0BS32 2-isopropylmalate synthase n=1 Tax=Granulibacter bethesdensis
CGDNIH1 RepID=Q0BS32_GRABC
Length = 527
Score = 81.3 bits (199), Expect = 3e-14
Identities = 51/131 (38%), Positives = 79/131 (60%), Gaps = 1/131 (0%)
Frame = +2
Query: 8 LGY-VLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
LGY L + L++ F RFK VA++KK + D D++ALV DEV + + + +++ G+
Sbjct: 358 LGYGELGENALNDAFRRFKEVADRKKVIYDDDIVALVDDEVNRSHERIRFVSVEVRAGSR 417
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
G +T+ V+L + DG+ A + G GPVDA + A+ +I L YS+ AVT+G DA A
Sbjct: 418 GPATAAVEL-EVDGELKQADAQGDGPVDAIFNAIGIIFTHDVELKLYSVGAVTDGADAQA 476
Query: 365 TTRVLIRGDNN 397
RV +R + N
Sbjct: 477 --RVTVRLEEN 485
[249][TOP]
>UniRef100_Q01UL9 2-isopropylmalate synthase n=1 Tax=Candidatus Solibacter usitatus
Ellin6076 RepID=Q01UL9_SOLUE
Length = 509
Score = 81.3 bits (199), Expect = 3e-14
Identities = 45/124 (36%), Positives = 70/124 (56%)
Frame = +2
Query: 5 ELGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALVSDEVFQPEAVWKLLDMQITCGTL 184
+LGY L D +L + RF +VA++K+ V D DLIA++ DE+ AV++L + I GT
Sbjct: 341 KLGYELSDLELDQAYRRFLSVADKKQEVFDEDLIAILRDEIHPLPAVYELQYLHIYSGTS 400
Query: 185 GLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDAIA 364
+ T+TV+L S G ++G GPVDA +A+ + A L Y + VT G +A+
Sbjct: 401 AIPTATVRLLVS-GDTREGAAIGDGPVDAVCRAISQVTATAAKLQRYEIRGVTSGTEAMG 459
Query: 365 TTRV 376
+
Sbjct: 460 EVTI 463
[250][TOP]
>UniRef100_A7HBI1 2-isopropylmalate synthase n=1 Tax=Anaeromyxobacter sp. Fw109-5
RepID=A7HBI1_ANADF
Length = 522
Score = 81.3 bits (199), Expect = 3e-14
Identities = 46/119 (38%), Positives = 68/119 (57%), Gaps = 2/119 (1%)
Frame = +2
Query: 8 LGYVLDDGQLSNLFWRFKAVAEQKKRVTDADLIALV--SDEVFQPEAVWKLLDMQITCGT 181
LGY LDD + +F FK +A++KK + DAD+ ALV + Q W+L + T GT
Sbjct: 346 LGYGLDDPTIDKVFQDFKVLADKKKDIYDADIEALVVHGQILAQGGRAWELDALSTTSGT 405
Query: 182 LGLSTSTVKLADSDGKEHVACSVGTGPVDAAYKAVDLIVKEPATLLEYSMNAVTEGIDA 358
L ++V L DG++H + G GPVDA Y+A++ I P L +Y + +V+ G DA
Sbjct: 406 GTLPVASVALRSRDGEQHRDAATGDGPVDAVYRAIEKITGIPVKLRDYQIVSVSTGEDA 464