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[1][TOP]
>UniRef100_Q94AR8 3-isopropylmalate dehydratase n=1 Tax=Arabidopsis thaliana
RepID=LEUC_ARATH
Length = 509
Score = 303 bits (775), Expect = 7e-81
Identities = 145/145 (100%), Positives = 145/145 (100%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG
Sbjct: 365 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 424
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI
Sbjct: 425 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 484
Query: 171 YLASPYTAAASALTGRVADPREFLQ 97
YLASPYTAAASALTGRVADPREFLQ
Sbjct: 485 YLASPYTAAASALTGRVADPREFLQ 509
[2][TOP]
>UniRef100_C0Z3H8 AT4G13430 protein n=1 Tax=Arabidopsis thaliana RepID=C0Z3H8_ARATH
Length = 175
Score = 295 bits (756), Expect = 1e-78
Identities = 141/141 (100%), Positives = 141/141 (100%)
Frame = -3
Query: 519 DRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKTC 340
DRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKTC
Sbjct: 35 DRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKTC 94
Query: 339 AQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYLAS 160
AQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYLAS
Sbjct: 95 AQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYLAS 154
Query: 159 PYTAAASALTGRVADPREFLQ 97
PYTAAASALTGRVADPREFLQ
Sbjct: 155 PYTAAASALTGRVADPREFLQ 175
[3][TOP]
>UniRef100_UPI0001983BAD PREDICTED: similar to Os02g0125100 n=1 Tax=Vitis vinifera
RepID=UPI0001983BAD
Length = 508
Score = 287 bits (734), Expect = 4e-76
Identities = 134/145 (92%), Positives = 141/145 (97%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKIDRVYIGSCTGGKTEDF+AAAK+FHA+G+KVKVPTFLVPATQKVWMDVY+LPVPG G
Sbjct: 364 DVKIDRVYIGSCTGGKTEDFLAAAKVFHASGKKVKVPTFLVPATQKVWMDVYSLPVPGCG 423
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
GKTC+QIFEEAGCDTPASPSCGACLGGP DTYAR+NEPQVCVSTTNRNFPGRMGHKEGQI
Sbjct: 424 GKTCSQIFEEAGCDTPASPSCGACLGGPRDTYARMNEPQVCVSTTNRNFPGRMGHKEGQI 483
Query: 171 YLASPYTAAASALTGRVADPREFLQ 97
YLASPYTAAASALTG V DPREFLQ
Sbjct: 484 YLASPYTAAASALTGFVTDPREFLQ 508
[4][TOP]
>UniRef100_B9SQS5 3-isopropylmalate dehydratase, putative n=1 Tax=Ricinus communis
RepID=B9SQS5_RICCO
Length = 510
Score = 283 bits (723), Expect = 7e-75
Identities = 133/145 (91%), Positives = 140/145 (96%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKIDRVYIGSCTGGKTEDFMAAAK+F A+G+KVKVPTFLVPATQKVWMDVY+LPVPG+G
Sbjct: 366 DVKIDRVYIGSCTGGKTEDFMAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 425
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
GKTC+QIFEEAGCDTPASPSCGACLGGP DTYAR+NEP VCVSTTNRNFPGRMGHKEGQI
Sbjct: 426 GKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPMVCVSTTNRNFPGRMGHKEGQI 485
Query: 171 YLASPYTAAASALTGRVADPREFLQ 97
YLASPYTAAASALTG V DPREFLQ
Sbjct: 486 YLASPYTAAASALTGYVTDPREFLQ 510
[5][TOP]
>UniRef100_B9HSU8 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9HSU8_POPTR
Length = 462
Score = 280 bits (715), Expect = 6e-74
Identities = 132/145 (91%), Positives = 138/145 (95%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKIDRVYIGSCTGGKTEDFMA AK+F A+G+KVKVPTFLVPATQKVWMDVY LPVPG+G
Sbjct: 318 DVKIDRVYIGSCTGGKTEDFMAVAKVFLASGKKVKVPTFLVPATQKVWMDVYTLPVPGSG 377
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
GKTCAQIFEEAGCDTPASPSCGACLGGP DT+AR+NEP VCVSTTNRNFPGRMGHKEGQI
Sbjct: 378 GKTCAQIFEEAGCDTPASPSCGACLGGPKDTHARMNEPMVCVSTTNRNFPGRMGHKEGQI 437
Query: 171 YLASPYTAAASALTGRVADPREFLQ 97
YLASPYTAAASALTG V DPREFLQ
Sbjct: 438 YLASPYTAAASALTGFVTDPREFLQ 462
[6][TOP]
>UniRef100_UPI0001983576 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI0001983576
Length = 508
Score = 279 bits (713), Expect = 1e-73
Identities = 129/144 (89%), Positives = 138/144 (95%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKIDRVYIGSCTGGKTEDF+AAAK+FHA+G+KVKVPTFLVPATQKVWMDVY+LPVPG G
Sbjct: 364 DVKIDRVYIGSCTGGKTEDFLAAAKVFHASGKKVKVPTFLVPATQKVWMDVYSLPVPGCG 423
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
GKTC+QIFEEAGCDTPASP+CGAC+GGP DTYAR+NEPQVCVSTTNRNFPGRMGHKE QI
Sbjct: 424 GKTCSQIFEEAGCDTPASPTCGACMGGPRDTYARMNEPQVCVSTTNRNFPGRMGHKESQI 483
Query: 171 YLASPYTAAASALTGRVADPREFL 100
YLASPYTAAASAL G V DPREFL
Sbjct: 484 YLASPYTAAASALRGYVTDPREFL 507
[7][TOP]
>UniRef100_C5XT62 Putative uncharacterized protein Sb04g002120 n=1 Tax=Sorghum
bicolor RepID=C5XT62_SORBI
Length = 507
Score = 278 bits (711), Expect = 2e-73
Identities = 129/144 (89%), Positives = 139/144 (96%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVK+DRVYIGSCTGGKTEDF+AAAK+F A+G+KVKVPTFLVPATQKVWMDVY+LPVPG+G
Sbjct: 363 DVKVDRVYIGSCTGGKTEDFLAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 422
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
GKTC+QIFEEAGCDTPASPSCGACLGGP DTYAR+NEP VCVSTTNRNFPGRMGHKEGQI
Sbjct: 423 GKTCSQIFEEAGCDTPASPSCGACLGGPRDTYARMNEPMVCVSTTNRNFPGRMGHKEGQI 482
Query: 171 YLASPYTAAASALTGRVADPREFL 100
YLASPYTAAASALTG V DPR+FL
Sbjct: 483 YLASPYTAAASALTGYVTDPRDFL 506
[8][TOP]
>UniRef100_C4JBG7 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=C4JBG7_MAIZE
Length = 505
Score = 278 bits (711), Expect = 2e-73
Identities = 130/144 (90%), Positives = 139/144 (96%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKIDRVYIGSCTGGKTEDF+AAAK+F A+G+KVKVPTFLVPATQKVWMDVY+LPVPG+G
Sbjct: 361 DVKIDRVYIGSCTGGKTEDFLAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 420
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
GKTCAQIFEEAGCDTPASP+CGACLGGP DTYAR+NEP VCVSTTNRNFPGRMGHKEGQI
Sbjct: 421 GKTCAQIFEEAGCDTPASPNCGACLGGPRDTYARMNEPTVCVSTTNRNFPGRMGHKEGQI 480
Query: 171 YLASPYTAAASALTGRVADPREFL 100
YLASPYTAAASALTG V DPR+FL
Sbjct: 481 YLASPYTAAASALTGYVTDPRDFL 504
[9][TOP]
>UniRef100_B6U6T6 3-isopropylmalate dehydratase large subunit 2 n=1 Tax=Zea mays
RepID=B6U6T6_MAIZE
Length = 504
Score = 277 bits (708), Expect = 4e-73
Identities = 129/144 (89%), Positives = 139/144 (96%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKIDRVYIGSCTGGKTEDF+AAAKLF A+G+KVKVPTFLVPATQKVW+DVY+LPVPG+G
Sbjct: 360 DVKIDRVYIGSCTGGKTEDFLAAAKLFLASGKKVKVPTFLVPATQKVWLDVYSLPVPGSG 419
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
GKTC+QIFEEAGCDTPASP+CGACLGGP DTYAR+NEP VCVSTTNRNFPGRMGHKEGQI
Sbjct: 420 GKTCSQIFEEAGCDTPASPNCGACLGGPRDTYARMNEPTVCVSTTNRNFPGRMGHKEGQI 479
Query: 171 YLASPYTAAASALTGRVADPREFL 100
YLASPYTAAASALTG V DPR+FL
Sbjct: 480 YLASPYTAAASALTGYVTDPRDFL 503
[10][TOP]
>UniRef100_C4IZQ5 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=C4IZQ5_MAIZE
Length = 505
Score = 276 bits (707), Expect = 5e-73
Identities = 129/144 (89%), Positives = 138/144 (95%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKIDRVYIGSCTGGKTEDF+AA K+F A+G+KVKVPTFLVPATQKVWMDVY+LPVPG+G
Sbjct: 361 DVKIDRVYIGSCTGGKTEDFLAAVKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 420
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
GKTCAQIFEEAGCDTPASP+CGACLGGP DTYAR+NEP VCVSTTNRNFPGRMGHKEGQI
Sbjct: 421 GKTCAQIFEEAGCDTPASPNCGACLGGPRDTYARMNEPTVCVSTTNRNFPGRMGHKEGQI 480
Query: 171 YLASPYTAAASALTGRVADPREFL 100
YLASPYTAAASALTG V DPR+FL
Sbjct: 481 YLASPYTAAASALTGYVTDPRDFL 504
[11][TOP]
>UniRef100_Q6Z702 Os02g0125100 protein n=2 Tax=Oryza sativa RepID=Q6Z702_ORYSJ
Length = 514
Score = 276 bits (706), Expect = 7e-73
Identities = 128/144 (88%), Positives = 138/144 (95%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKIDRVYIGSCTGGKTEDF AAAK+F A+G+KVKVPTFLVPATQKVWMD+Y++PVPGAG
Sbjct: 370 DVKIDRVYIGSCTGGKTEDFFAAAKVFLASGKKVKVPTFLVPATQKVWMDIYSIPVPGAG 429
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
GKTC+QIFEEAGCDTPASPSCGACLGGP DTYAR+NEP VCVSTTNRNFPGRMGHKEGQI
Sbjct: 430 GKTCSQIFEEAGCDTPASPSCGACLGGPRDTYARMNEPMVCVSTTNRNFPGRMGHKEGQI 489
Query: 171 YLASPYTAAASALTGRVADPREFL 100
YLASP+TAAASALTG V DPR+FL
Sbjct: 490 YLASPFTAAASALTGYVTDPRDFL 513
[12][TOP]
>UniRef100_B4FG11 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=B4FG11_MAIZE
Length = 505
Score = 275 bits (704), Expect = 1e-72
Identities = 127/144 (88%), Positives = 139/144 (96%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKIDRVYIGSCTGGKTEDF+AAAK+F A+G+KVKVPTFLVPATQKVW+D+Y+LPVPG+G
Sbjct: 361 DVKIDRVYIGSCTGGKTEDFLAAAKVFLASGKKVKVPTFLVPATQKVWLDIYSLPVPGSG 420
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
GKTC+QIFEEAGCDTPASP+CGACLGGP DTYAR+NEP VCVSTTNRNFPGRMGHKEGQI
Sbjct: 421 GKTCSQIFEEAGCDTPASPNCGACLGGPRDTYARMNEPTVCVSTTNRNFPGRMGHKEGQI 480
Query: 171 YLASPYTAAASALTGRVADPREFL 100
YLASPYTAAASALTG V DPR+FL
Sbjct: 481 YLASPYTAAASALTGYVTDPRDFL 504
[13][TOP]
>UniRef100_B9SQS6 3-isopropylmalate dehydratase, putative n=1 Tax=Ricinus communis
RepID=B9SQS6_RICCO
Length = 621
Score = 273 bits (699), Expect = 4e-72
Identities = 127/145 (87%), Positives = 137/145 (94%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKIDRVYIGSCTGGKTEDF AAAK+F A+G+KVKVPTFLVPATQKVWMDVY++PVPG+G
Sbjct: 477 DVKIDRVYIGSCTGGKTEDFTAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSIPVPGSG 536
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
GKTC++IFEEAGCDTPASP C AC+GGP DTYAR+NEP VCVSTTNRNFPGRMGHKEGQI
Sbjct: 537 GKTCSRIFEEAGCDTPASPGCSACMGGPRDTYARMNEPMVCVSTTNRNFPGRMGHKEGQI 596
Query: 171 YLASPYTAAASALTGRVADPREFLQ 97
YLASPYTAAASALTG V DPREFLQ
Sbjct: 597 YLASPYTAAASALTGYVTDPREFLQ 621
[14][TOP]
>UniRef100_B9HKV5 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9HKV5_POPTR
Length = 443
Score = 271 bits (694), Expect = 2e-71
Identities = 126/145 (86%), Positives = 138/145 (95%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKIDRVYIGSCTGGKTEDFMAAAK+F A+G+KV+VPTFLVPAT KVWMD+Y LPVPG+G
Sbjct: 299 DVKIDRVYIGSCTGGKTEDFMAAAKVFLASGKKVRVPTFLVPATGKVWMDLYTLPVPGSG 358
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
GKTC+QIFEEAGCDTPA+P+CGAC+GGP DTYAR+N+P VCVSTTNRNFPGRMGHKEGQI
Sbjct: 359 GKTCSQIFEEAGCDTPANPTCGACMGGPRDTYARMNKPVVCVSTTNRNFPGRMGHKEGQI 418
Query: 171 YLASPYTAAASALTGRVADPREFLQ 97
YLASPYTAAASALTG V DPREFLQ
Sbjct: 419 YLASPYTAAASALTGFVTDPREFLQ 443
[15][TOP]
>UniRef100_C0PRG9 Putative uncharacterized protein n=1 Tax=Picea sitchensis
RepID=C0PRG9_PICSI
Length = 237
Score = 269 bits (688), Expect = 8e-71
Identities = 126/143 (88%), Positives = 134/143 (93%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KIDRVYIGSCTGGKTEDFMAAAK+ +AG+KVKVPTFLVPATQKVWMD+Y LPVPG G
Sbjct: 95 IKIDRVYIGSCTGGKTEDFMAAAKILISAGQKVKVPTFLVPATQKVWMDLYTLPVPGGNG 154
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
KTCAQIFEEAGCDTPASP+CGACLGGP DTYAR+N PQVCVSTTNRNFPGRMGHKEGQIY
Sbjct: 155 KTCAQIFEEAGCDTPASPNCGACLGGPRDTYARMNVPQVCVSTTNRNFPGRMGHKEGQIY 214
Query: 168 LASPYTAAASALTGRVADPREFL 100
LASPYTAAASALTG V DPR+FL
Sbjct: 215 LASPYTAAASALTGFVTDPRDFL 237
[16][TOP]
>UniRef100_B8LQY6 Putative uncharacterized protein n=1 Tax=Picea sitchensis
RepID=B8LQY6_PICSI
Length = 515
Score = 269 bits (688), Expect = 8e-71
Identities = 126/143 (88%), Positives = 134/143 (93%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KIDRVYIGSCTGGKTEDFMAAAK+ +AG+KVKVPTFLVPATQKVWMD+Y LPVPG G
Sbjct: 373 IKIDRVYIGSCTGGKTEDFMAAAKILISAGQKVKVPTFLVPATQKVWMDLYTLPVPGGNG 432
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
KTCAQIFEEAGCDTPASP+CGACLGGP DTYAR+N PQVCVSTTNRNFPGRMGHKEGQIY
Sbjct: 433 KTCAQIFEEAGCDTPASPNCGACLGGPRDTYARMNVPQVCVSTTNRNFPGRMGHKEGQIY 492
Query: 168 LASPYTAAASALTGRVADPREFL 100
LASPYTAAASALTG V DPR+FL
Sbjct: 493 LASPYTAAASALTGFVTDPRDFL 515
[17][TOP]
>UniRef100_A5AN38 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5AN38_VITVI
Length = 252
Score = 268 bits (686), Expect = 1e-70
Identities = 133/178 (74%), Positives = 140/178 (78%), Gaps = 33/178 (18%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKIDRVYIGSCTGGKTEDF+AAAK+FH +G+KVKVPTFLVPATQKVWMDVY+LPVPG G
Sbjct: 75 DVKIDRVYIGSCTGGKTEDFLAAAKVFHVSGKKVKVPTFLVPATQKVWMDVYSLPVPGCG 134
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQ--------------------- 235
GKTC+QIFEEAGCDTPASPSCGACLGGP DTYAR+NEPQ
Sbjct: 135 GKTCSQIFEEAGCDTPASPSCGACLGGPRDTYARMNEPQATFGCGWIPFFFGHGGCMINY 194
Query: 234 ------------VCVSTTNRNFPGRMGHKEGQIYLASPYTAAASALTGRVADPREFLQ 97
VCVSTTNRNFPGRMGHKEGQIYLASPYTAAASALTG V DPREFLQ
Sbjct: 195 LMILDLLYLHLKVCVSTTNRNFPGRMGHKEGQIYLASPYTAAASALTGFVTDPREFLQ 252
[18][TOP]
>UniRef100_B8LQ24 Putative uncharacterized protein n=1 Tax=Picea sitchensis
RepID=B8LQ24_PICSI
Length = 516
Score = 267 bits (682), Expect = 4e-70
Identities = 124/143 (86%), Positives = 134/143 (93%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KIDRVYIGSCTGGKTEDFMAAAK+ +AG+KVKVPTFLVPATQKVWMD+Y LPVPG G
Sbjct: 374 IKIDRVYIGSCTGGKTEDFMAAAKIMISAGQKVKVPTFLVPATQKVWMDLYTLPVPGGNG 433
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
KTC+QIFEEAGCDTPA+P+CGACLGGP DTYAR+N PQVCVSTTN+NFPGRMGHKEGQIY
Sbjct: 434 KTCSQIFEEAGCDTPANPNCGACLGGPRDTYARMNVPQVCVSTTNKNFPGRMGHKEGQIY 493
Query: 168 LASPYTAAASALTGRVADPREFL 100
LASPYTAAASALTG V DPREFL
Sbjct: 494 LASPYTAAASALTGFVTDPREFL 516
[19][TOP]
>UniRef100_A9TGU1 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9TGU1_PHYPA
Length = 518
Score = 266 bits (681), Expect = 5e-70
Identities = 124/144 (86%), Positives = 135/144 (93%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKIDRVYIGSCTGGKTEDF+AAA+L +G+KVKVPTFLVPATQKVWMD+Y+LPVPG
Sbjct: 375 DVKIDRVYIGSCTGGKTEDFLAAAELLAISGQKVKVPTFLVPATQKVWMDLYSLPVPGTD 434
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
GKTCA+IF++AGCDTPASPSC ACLGGP DTYAR+N+PQVCVSTTNRNFPGRMGHKEGQI
Sbjct: 435 GKTCAEIFQQAGCDTPASPSCAACLGGPRDTYARMNDPQVCVSTTNRNFPGRMGHKEGQI 494
Query: 171 YLASPYTAAASALTGRVADPREFL 100
YLASPYTAAASALTG V DPREFL
Sbjct: 495 YLASPYTAAASALTGFVTDPREFL 518
[20][TOP]
>UniRef100_B6TYJ6 3-isopropylmalate dehydratase large subunit 2 n=1 Tax=Zea mays
RepID=B6TYJ6_MAIZE
Length = 492
Score = 260 bits (664), Expect = 5e-68
Identities = 121/132 (91%), Positives = 129/132 (97%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKIDRVYIGSCTGGKTEDF+AAAK+F A+G+KVKVPTFLVPATQKVWMDVY+LPVPG+G
Sbjct: 361 DVKIDRVYIGSCTGGKTEDFLAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 420
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
GKTCAQIFEEAGCDTPASP+CGACLGGP DTYAR+NEP VCVSTTNRNFPGRMGHKEGQI
Sbjct: 421 GKTCAQIFEEAGCDTPASPNCGACLGGPRDTYARMNEPTVCVSTTNRNFPGRMGHKEGQI 480
Query: 171 YLASPYTAAASA 136
YLASPYTAAASA
Sbjct: 481 YLASPYTAAASA 492
[21][TOP]
>UniRef100_A8JG03 Isopropylmalate dehydratase, large subunit n=1 Tax=Chlamydomonas
reinhardtii RepID=A8JG03_CHLRE
Length = 487
Score = 252 bits (644), Expect = 1e-65
Identities = 117/144 (81%), Positives = 131/144 (90%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKIDRVYIGSCTGGKTEDF++AAKLF+ A R+VKVPT+LVPATQKVW DVY +PVPG
Sbjct: 344 DVKIDRVYIGSCTGGKTEDFISAAKLFYRAKRQVKVPTYLVPATQKVWADVYTMPVPGCD 403
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
GKT A+IFEE+GC TPA+PSC ACLGGP DT+AR+NEP+VCVSTTNRNFPGRMGHKEGQI
Sbjct: 404 GKTAAEIFEESGCITPAAPSCAACLGGPRDTFARMNEPEVCVSTTNRNFPGRMGHKEGQI 463
Query: 171 YLASPYTAAASALTGRVADPREFL 100
YLASPYTAAASAL G V DPRE++
Sbjct: 464 YLASPYTAAASALKGFVCDPREYM 487
[22][TOP]
>UniRef100_Q111B2 Homoaconitate hydratase family protein n=1 Tax=Trichodesmium
erythraeum IMS101 RepID=Q111B2_TRIEI
Length = 439
Score = 205 bits (521), Expect = 2e-51
Identities = 100/144 (69%), Positives = 118/144 (81%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKIDRVYIGSCTGGKT DF+ AAKL +VKVPT+LVPATQKV+ D++ +
Sbjct: 301 DVKIDRVYIGSCTGGKTSDFLHAAKLIK--DHQVKVPTYLVPATQKVYEDLFIIK---HD 355
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
GKT ++IF +AGC PA+PSC ACLGGP DT+ RLNEP++CVSTTNRNFPGRMG+K+ Q+
Sbjct: 356 GKTLSEIFLDAGCIEPAAPSCAACLGGPKDTFGRLNEPEICVSTTNRNFPGRMGNKQAQV 415
Query: 171 YLASPYTAAASALTGRVADPREFL 100
YLASPYTAAASALTG V DPREF+
Sbjct: 416 YLASPYTAAASALTGYVTDPREFM 439
[23][TOP]
>UniRef100_A7QRJ3 Chromosome chr8 scaffold_150, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7QRJ3_VITVI
Length = 424
Score = 201 bits (510), Expect = 4e-50
Identities = 91/107 (85%), Positives = 100/107 (93%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKIDRVYIGSCTGGKTEDF+AAAK+FHA+G+KVKVPTFLVPATQKVWMDVY+LPVPG G
Sbjct: 318 DVKIDRVYIGSCTGGKTEDFLAAAKVFHASGKKVKVPTFLVPATQKVWMDVYSLPVPGCG 377
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNR 211
GKTC+QIFEEAGCDTPASPSCGACLGGP DTYAR+NEPQ + N+
Sbjct: 378 GKTCSQIFEEAGCDTPASPSCGACLGGPRDTYARMNEPQASMRLYNK 424
[24][TOP]
>UniRef100_A7NXJ3 Chromosome chr5 scaffold_2, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7NXJ3_VITVI
Length = 507
Score = 197 bits (501), Expect = 4e-49
Identities = 88/99 (88%), Positives = 97/99 (97%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKIDRVYIGSCTGGKTEDF+AAAK+FHA+G+KVKVPTFLVPATQKVWMDVY+LPVPG G
Sbjct: 381 DVKIDRVYIGSCTGGKTEDFLAAAKVFHASGKKVKVPTFLVPATQKVWMDVYSLPVPGCG 440
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQ 235
GKTC+QIFEEAGCDTPASP+CGAC+GGP DTYAR+NEPQ
Sbjct: 441 GKTCSQIFEEAGCDTPASPTCGACMGGPRDTYARMNEPQ 479
[25][TOP]
>UniRef100_A9PBQ8 Putative uncharacterized protein n=1 Tax=Populus trichocarpa
RepID=A9PBQ8_POPTR
Length = 97
Score = 186 bits (472), Expect = 9e-46
Identities = 84/97 (86%), Positives = 92/97 (94%)
Frame = -3
Query: 387 MDVYALPVPGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRN 208
MD+Y LPVPG+GGKTC+QIFEEAGCDTPA+P+CGAC+GGP DTYAR+N+P VCVSTTNRN
Sbjct: 1 MDLYTLPVPGSGGKTCSQIFEEAGCDTPANPTCGACMGGPRDTYARMNKPVVCVSTTNRN 60
Query: 207 FPGRMGHKEGQIYLASPYTAAASALTGRVADPREFLQ 97
FPGRMGHKEGQIYLASPYTAAASALTG V DPREFLQ
Sbjct: 61 FPGRMGHKEGQIYLASPYTAAASALTGFVTDPREFLQ 97
[26][TOP]
>UniRef100_C4C1N1 Homoaconitate hydratase family protein/3-isopropylmalate
dehydratase, large subunit n=1 Tax=Sebaldella termitidis
ATCC 33386 RepID=C4C1N1_9FUSO
Length = 435
Score = 174 bits (440), Expect = 5e-42
Identities = 87/144 (60%), Positives = 107/144 (74%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVK+DR YIGSCTGGKT DF+AAAK+ GRKV + TF+VP+T KV + + + G
Sbjct: 294 DVKLDRAYIGSCTGGKTTDFVAAAKILK--GRKVAIETFIVPSTVKVEEALSKIIIDG-- 349
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+TC +IFE+AGC PSC ACLGGP DT+ R + +V +STTNRNFPGRMG + Q+
Sbjct: 350 -ETCMEIFEKAGCKI-GPPSCAACLGGPVDTFGRTHANEVVISTTNRNFPGRMGSMDSQV 407
Query: 171 YLASPYTAAASALTGRVADPREFL 100
YLASPYTAAASA+TG + DPREFL
Sbjct: 408 YLASPYTAAASAVTGHITDPREFL 431
[27][TOP]
>UniRef100_B4D0Q5 Aconitate hydratase domain protein n=1 Tax=Chthoniobacter flavus
Ellin428 RepID=B4D0Q5_9BACT
Length = 456
Score = 163 bits (413), Expect = 6e-39
Identities = 82/143 (57%), Positives = 99/143 (69%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
V +DR YIGSCTGGKT DF+A A++ G+ VK+ TF VPAT KV V L G
Sbjct: 318 VSLDRAYIGSCTGGKTSDFLAFARV--VKGKSVKIDTFGVPATTKV---VQELKDTQWDG 372
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
++ I E AG + SC ACLGGP DT+ R+N P C+S TNRNFPGRMGHKE Q++
Sbjct: 373 QSVWNILESAGVRMTENASCAACLGGPVDTFGRMNTPLKCISATNRNFPGRMGHKESQVF 432
Query: 168 LASPYTAAASALTGRVADPREFL 100
LASPYT AASALTG++ DPREF+
Sbjct: 433 LASPYTVAASALTGKITDPREFI 455
[28][TOP]
>UniRef100_B9XBH0 Aconitate hydratase domain protein n=1 Tax=bacterium Ellin514
RepID=B9XBH0_9BACT
Length = 455
Score = 161 bits (408), Expect = 2e-38
Identities = 79/143 (55%), Positives = 99/143 (69%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVK+DR YIGSCTGGKT DF+ A++ G++V + TF VPAT ++ V+ L G
Sbjct: 316 DVKLDRAYIGSCTGGKTSDFLEFARVLK--GKRVMIDTFGVPATPEI---VHDLQTARWG 370
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
KT QI +AG + C ACLGGP DT+ R+N P C+S TNRNFPGRMGHKE Q+
Sbjct: 371 EKTVWQILVDAGVQMTENAGCAACLGGPVDTFGRMNTPMKCISATNRNFPGRMGHKESQV 430
Query: 171 YLASPYTAAASALTGRVADPREF 103
+LASP T AASALTG++ DPRE+
Sbjct: 431 FLASPATVAASALTGKITDPREY 453
[29][TOP]
>UniRef100_A1BES2 Homoaconitate hydratase family protein n=1 Tax=Chlorobium
phaeobacteroides DSM 266 RepID=A1BES2_CHLPD
Length = 431
Score = 160 bits (405), Expect = 5e-38
Identities = 86/141 (60%), Positives = 101/141 (71%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKT 343
I R YIGSCTGGK DFM AAK+ + G+KV VPT +VPAT KV D L + G+T
Sbjct: 297 ITRSYIGSCTGGKLSDFMMAAKILN--GKKVSVPTNIVPATVKVAAD---LAIEQYEGRT 351
Query: 342 CAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYLA 163
QIFE+AGC A PSC ACLGGP+DT R + V VSTTNRNFPGRMG K+ +YLA
Sbjct: 352 LKQIFEDAGCSI-ALPSCAACLGGPSDTVGRSVDNDVVVSTTNRNFPGRMGSKKAGVYLA 410
Query: 162 SPYTAAASALTGRVADPREFL 100
SP TAAASA+TG++ DPR+FL
Sbjct: 411 SPLTAAASAITGKLTDPRDFL 431
[30][TOP]
>UniRef100_UPI00016C35D3 homoaconitate hydratase family protein n=1 Tax=Gemmata
obscuriglobus UQM 2246 RepID=UPI00016C35D3
Length = 435
Score = 157 bits (397), Expect = 4e-37
Identities = 82/142 (57%), Positives = 98/142 (69%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
K+DR YIGSCTGGK DF AAA+L + G+ VK+ TF+VPAT +V L GG+
Sbjct: 299 KLDRAYIGSCTGGKLTDFKAAAQLLN--GKTVKIDTFVVPATTEV---ARGLDTETIGGR 353
Query: 345 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
+ IF AG SC ACLGGP+DT+ RLN P C+STTNRNFPGRMGHK+ Q++L
Sbjct: 354 SLRDIFLSAGAKI-GDASCAACLGGPSDTFGRLNAPISCISTTNRNFPGRMGHKDAQVFL 412
Query: 165 ASPYTAAASALTGRVADPREFL 100
ASP T AASALTG +AD RE L
Sbjct: 413 ASPLTVAASALTGTIADCRELL 434
[31][TOP]
>UniRef100_B3E0P6 3-isopropylmalate dehydratase large subunit n=1
Tax=Methylacidiphilum infernorum V4 RepID=B3E0P6_METI4
Length = 455
Score = 157 bits (397), Expect = 4e-37
Identities = 77/143 (53%), Positives = 98/143 (68%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
VKIDR Y+GSCTGGK DF+A A + R V V TF VP+T +V ++ + + G
Sbjct: 318 VKIDRAYLGSCTGGKLSDFIAFASILK--NRTVSVETFAVPSTPEVVDQLHKIEIEG--- 372
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
K+ EAG +PSC ACLGGP DT+ R+N+P VC+S+TNRNFPGRMG K Q+Y
Sbjct: 373 KSIWDTLREAGVQITENPSCAACLGGPMDTFGRVNKPLVCISSTNRNFPGRMGDKSSQVY 432
Query: 168 LASPYTAAASALTGRVADPREFL 100
LASP T A+SA+TG++ DPREFL
Sbjct: 433 LASPLTVASSAITGKITDPREFL 455
[32][TOP]
>UniRef100_B4SDL0 Homoaconitate hydratase family protein n=1 Tax=Pelodictyon
phaeoclathratiforme BU-1 RepID=B4SDL0_PELPB
Length = 431
Score = 154 bits (389), Expect = 4e-36
Identities = 86/142 (60%), Positives = 98/142 (69%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
KI + YIGSCTGGK DFM AAK+ G KV V T +VPAT KV D L G+
Sbjct: 296 KITKSYIGSCTGGKLTDFMMAAKILK--GHKVSVTTNIVPATVKVARD---LECELYDGQ 350
Query: 345 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
+ QIFE+AGC T A PSC ACLGGPADT R + V VSTTNRNFPGRMG K +YL
Sbjct: 351 SLKQIFEDAGC-TIALPSCAACLGGPADTVGRSVDNDVVVSTTNRNFPGRMGSKHAGVYL 409
Query: 165 ASPYTAAASALTGRVADPREFL 100
ASP TAAASA+TG++ DPR+FL
Sbjct: 410 ASPLTAAASAITGKLTDPRDFL 431
[33][TOP]
>UniRef100_Q3APC5 3-isopropylmalate dehydratase n=1 Tax=Chlorobium chlorochromatii
CaD3 RepID=Q3APC5_CHLCH
Length = 431
Score = 154 bits (388), Expect = 5e-36
Identities = 84/142 (59%), Positives = 98/142 (69%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
KI + YIGSCTGGK DFM AAK+ G+KV V T +VPAT V +L GK
Sbjct: 296 KITKSYIGSCTGGKLSDFMMAAKILK--GQKVTVTTTIVPATTLV---ARSLETEQYDGK 350
Query: 345 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
+ QIFEEAGC+ A PSC ACLGGPADT R + + VSTTNRNFPGRMG K +YL
Sbjct: 351 SLKQIFEEAGCNV-ALPSCAACLGGPADTVGRSVDNDLVVSTTNRNFPGRMGSKHAGVYL 409
Query: 165 ASPYTAAASALTGRVADPREFL 100
ASP TAAASA+TG++ DPR+FL
Sbjct: 410 ASPLTAAASAITGKLTDPRDFL 431
[34][TOP]
>UniRef100_B3EHN8 Homoaconitate hydratase family protein n=1 Tax=Chlorobium limicola
DSM 245 RepID=B3EHN8_CHLL2
Length = 431
Score = 154 bits (388), Expect = 5e-36
Identities = 85/142 (59%), Positives = 98/142 (69%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
KI + YIGSCTGGK DFM AAK+ G++V VPT +VPAT V AL G
Sbjct: 296 KITKSYIGSCTGGKLTDFMLAAKILK--GKQVTVPTNIVPATVLV---ARALECETWEGV 350
Query: 345 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
T +IFE+AGC A PSC ACLGGPADT R + V VSTTNRNFPGRMG K+ +YL
Sbjct: 351 TLKKIFEDAGCSI-ALPSCAACLGGPADTVGRSADQDVVVSTTNRNFPGRMGSKKADVYL 409
Query: 165 ASPYTAAASALTGRVADPREFL 100
ASP TAAASA+TG++ DPREFL
Sbjct: 410 ASPLTAAASAVTGKLTDPREFL 431
[35][TOP]
>UniRef100_A4SFC8 Homoaconitate hydratase family protein n=1 Tax=Chlorobium
phaeovibrioides DSM 265 RepID=A4SFC8_PROVI
Length = 431
Score = 153 bits (386), Expect = 8e-36
Identities = 82/142 (57%), Positives = 98/142 (69%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
KI + YIGSCTGGK DF AAK+ +G++V VPT +VPAT KV D L GK
Sbjct: 296 KITKSYIGSCTGGKLADFKLAAKIL--SGKRVSVPTNIVPATVKVAHD---LETELYNGK 350
Query: 345 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
+ IFE+AGC A PSC ACLGGP DT R + V VSTTNRNFPGRMG K+ ++YL
Sbjct: 351 SLKSIFEDAGCSI-ALPSCAACLGGPTDTVGRSVDRDVVVSTTNRNFPGRMGSKQAEVYL 409
Query: 165 ASPYTAAASALTGRVADPREFL 100
ASP TAAASA+TG++ DPR +L
Sbjct: 410 ASPLTAAASAITGKLTDPRNYL 431
[36][TOP]
>UniRef100_B4S6N0 Homoaconitate hydratase family protein n=1 Tax=Prosthecochloris
aestuarii DSM 271 RepID=B4S6N0_PROA2
Length = 432
Score = 150 bits (380), Expect = 4e-35
Identities = 79/142 (55%), Positives = 100/142 (70%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
+I + YIGSCTGGK DF AAK+ + G++V + T +VPAT +V +L GK
Sbjct: 296 RITKSYIGSCTGGKLSDFKMAAKILN--GQQVSIQTNIVPATVEV---AKSLETEQYEGK 350
Query: 345 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
+ ++ E+AGC T A PSC ACLGGPADT+ R + + VSTTNRNFPGRMG K+ +YL
Sbjct: 351 SIRKVLEDAGC-TIAQPSCAACLGGPADTFGRSEDNDLVVSTTNRNFPGRMGSKKAGVYL 409
Query: 165 ASPYTAAASALTGRVADPREFL 100
ASP TAAASA+TGR+ DPREFL
Sbjct: 410 ASPLTAAASAITGRLTDPREFL 431
[37][TOP]
>UniRef100_Q3B597 3-isopropylmalate dehydratase n=1 Tax=Chlorobium luteolum DSM 273
RepID=Q3B597_PELLD
Length = 431
Score = 150 bits (379), Expect = 5e-35
Identities = 82/141 (58%), Positives = 98/141 (69%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKT 343
I + YIGSCTGGK DF AA++ + GRKV V T +VPAT +V D L GKT
Sbjct: 297 ITKSYIGSCTGGKLTDFKMAARILN--GRKVAVTTNIVPATVQVARD---LEQEMHEGKT 351
Query: 342 CAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYLA 163
QIF EAGC+ A PSC ACLGGPADT R + + VSTTNRNFPGRMG K ++YLA
Sbjct: 352 LKQIFMEAGCNI-ALPSCAACLGGPADTVGRSVDRDIVVSTTNRNFPGRMGSKNAEVYLA 410
Query: 162 SPYTAAASALTGRVADPREFL 100
SP TAAASA+TG++ DPR+F+
Sbjct: 411 SPLTAAASAITGKLTDPRDFI 431
[38][TOP]
>UniRef100_Q0YQD5 Homoaconitate hydratase family protein:3-isopropylmalate
dehydratase, prokaryotic n=1 Tax=Chlorobium ferrooxidans
DSM 13031 RepID=Q0YQD5_9CHLB
Length = 431
Score = 148 bits (373), Expect = 3e-34
Identities = 82/142 (57%), Positives = 96/142 (67%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
KI + YIGSCTGGK DF+ AAK+ G+KV V T +VPAT V AL G
Sbjct: 296 KITKSYIGSCTGGKLTDFVMAAKILK--GKKVSVTTNIVPATVLV---ARALETERFEGV 350
Query: 345 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
T QIFE+AGC A PSC ACLGGP+DT R + + VSTTNRNFPGRMG K +YL
Sbjct: 351 TLKQIFEDAGCSI-ALPSCAACLGGPSDTVGRSVDNDLVVSTTNRNFPGRMGSKHAGVYL 409
Query: 165 ASPYTAAASALTGRVADPREFL 100
ASP TAAASA+TG++ DPR+FL
Sbjct: 410 ASPLTAAASAVTGKLTDPRDFL 431
[39][TOP]
>UniRef100_C1ZRL8 Homoaconitate hydratase family protein/3-isopropylmalate
dehydratase, large subunit n=1 Tax=Rhodothermus marinus
DSM 4252 RepID=C1ZRL8_RHOMR
Length = 432
Score = 148 bits (373), Expect = 3e-34
Identities = 76/142 (53%), Positives = 97/142 (68%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
K+DR YIGSCTGGK EDF+AAA++ G++V++ TF+VPA+ V ++ + G
Sbjct: 296 KLDRAYIGSCTGGKLEDFIAAARILK--GQEVRIDTFVVPASTYVEQQLHHYKIDGV--- 350
Query: 345 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
+ IF AGC SCGACLGGP DT+ R + +V +STTNRNFPGRMG K+ +YL
Sbjct: 351 SLYDIFVNAGCKI-GHASCGACLGGPPDTFGRTHGTEVVISTTNRNFPGRMGSKQASVYL 409
Query: 165 ASPYTAAASALTGRVADPREFL 100
ASP T AASALTG + DPRE L
Sbjct: 410 ASPLTVAASALTGVITDPREVL 431
[40][TOP]
>UniRef100_Q8KER8 3-isopropylmalate dehydratase, large subunit, putative n=1
Tax=Chlorobaculum tepidum RepID=Q8KER8_CHLTE
Length = 431
Score = 145 bits (365), Expect = 2e-33
Identities = 81/141 (57%), Positives = 94/141 (66%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKT 343
I + YIGSCTGGK DF AAK+ G+KV V T +VPAT V L G+T
Sbjct: 297 ITKSYIGSCTGGKLTDFKLAAKILK--GKKVAVTTNIVPATVLV---ASQLETEMYDGQT 351
Query: 342 CAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYLA 163
IFEEAGC+ A PSC ACLGGP+DT R + V VSTTNRNFPGRMG K +YLA
Sbjct: 352 LRHIFEEAGCNI-ALPSCAACLGGPSDTVGRSVDNDVVVSTTNRNFPGRMGSKFASVYLA 410
Query: 162 SPYTAAASALTGRVADPREFL 100
SP TAAASA+TG++ DPR+FL
Sbjct: 411 SPLTAAASAITGKLTDPRDFL 431
[41][TOP]
>UniRef100_A6DRT0 3-isopropylmalate dehydratase n=1 Tax=Lentisphaera araneosa
HTCC2155 RepID=A6DRT0_9BACT
Length = 433
Score = 145 bits (365), Expect = 2e-33
Identities = 76/142 (53%), Positives = 96/142 (67%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKT 343
+ R YIGSCTGGKTEDF AAA++ + G+KV + TF+VP+T V D+ L KT
Sbjct: 297 LTRAYIGSCTGGKTEDFAAAAEIMY--GQKVAMDTFVVPSTTFVEKDLNTLKFKD---KT 351
Query: 342 CAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYLA 163
+IF EAGC P C ACLGGP DT+ R + ++ VSTTNRNFPGRMG + ++YLA
Sbjct: 352 YMEIFLEAGCRI-GPPGCAACLGGPEDTFGRTHAEEIVVSTTNRNFPGRMGSMQAKVYLA 410
Query: 162 SPYTAAASALTGRVADPREFLQ 97
SPY AAASALTG + P +L+
Sbjct: 411 SPYVAAASALTGVITKPDSYLE 432
[42][TOP]
>UniRef100_B3EKV4 Homoaconitate hydratase family protein n=1 Tax=Chlorobium
phaeobacteroides BS1 RepID=B3EKV4_CHLPB
Length = 432
Score = 143 bits (361), Expect = 7e-33
Identities = 79/143 (55%), Positives = 97/143 (67%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
KI + YIGSCTGGK DF+ AAK+ G V VPT +VPAT +V +L G+
Sbjct: 296 KITKSYIGSCTGGKLIDFVMAAKVLK--GNTVSVPTNIVPATVEV---AQSLTTEEFDGQ 350
Query: 345 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
I +EAGC T A PSC ACLGGP+DT+ R + + VSTTNRNFPGRMG K+ + L
Sbjct: 351 PIITILKEAGC-TIAPPSCAACLGGPSDTFGRSVDNDLVVSTTNRNFPGRMGSKKAGVCL 409
Query: 165 ASPYTAAASALTGRVADPREFLQ 97
ASP TAAASA+TG++ DPREFL+
Sbjct: 410 ASPLTAAASAITGKLTDPREFLR 432
[43][TOP]
>UniRef100_B3QM97 Homoaconitate hydratase family protein n=1 Tax=Chlorobaculum parvum
NCIB 8327 RepID=B3QM97_CHLP8
Length = 431
Score = 143 bits (360), Expect = 9e-33
Identities = 81/141 (57%), Positives = 94/141 (66%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKT 343
I + YIGSCTGGK DF AAK+ G+KV V T +VPAT V L G+T
Sbjct: 297 ITKSYIGSCTGGKITDFRLAAKILK--GKKVAVTTNIVPATVLV---ASQLENEMYDGQT 351
Query: 342 CAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYLA 163
IFEEAGC+ A PSC ACLGGP+DT R + V VSTTNRNFPGRMG K +YLA
Sbjct: 352 LRHIFEEAGCNI-ALPSCAACLGGPSDTVGRSVDNDVVVSTTNRNFPGRMGSKMAGVYLA 410
Query: 162 SPYTAAASALTGRVADPREFL 100
SP TAAASA+TG++ DPR+FL
Sbjct: 411 SPLTAAASAVTGKLTDPRDFL 431
[44][TOP]
>UniRef100_B3QSN7 Homoaconitate hydratase family protein n=1 Tax=Chloroherpeton
thalassium ATCC 35110 RepID=B3QSN7_CHLT3
Length = 431
Score = 142 bits (358), Expect = 1e-32
Identities = 74/142 (52%), Positives = 95/142 (66%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
K+ + Y+GSCTGGK DF AAK+ H G+ VKVPTF+VP + V + + G
Sbjct: 296 KLTKCYLGSCTGGKLTDFEFAAKVLH--GQTVKVPTFVVPGSTLVAKQLTEKTIDGM--- 350
Query: 345 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
T +IFE+AGC A SC ACLGGPADT R ++ +STTNRNFPGRMG K+ ++YL
Sbjct: 351 TYMEIFEKAGCII-AESSCAACLGGPADTVGRSSDGDTVISTTNRNFPGRMGSKKSEVYL 409
Query: 165 ASPYTAAASALTGRVADPREFL 100
ASP T AASA+ G + DPR+F+
Sbjct: 410 ASPLTVAASAVNGVITDPRDFV 431
[45][TOP]
>UniRef100_B2VKF3 3-isopropylmalate dehydratase large subunit n=1 Tax=Erwinia
tasmaniensis RepID=B2VKF3_ERWT9
Length = 436
Score = 141 bits (355), Expect = 3e-32
Identities = 71/140 (50%), Positives = 94/140 (67%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
+V I + YIGSCTGGK DF+AAA++ GRKV VPTF VPAT++V+ + + + G
Sbjct: 294 NVAISQAYIGSCTGGKLADFIAAARVIK--GRKVVVPTFAVPATKEVFHGLISTDIDG-- 349
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
++ +I +AG + C AC GGPADT+ R+N+P +STTNRNF GRMGHK I
Sbjct: 350 -QSVYRILCDAGVQLSSESGCAACCGGPADTFGRVNQPISVISTTNRNFVGRMGHKRANI 408
Query: 171 YLASPYTAAASALTGRVADP 112
YLASPY AA+A+TG + P
Sbjct: 409 YLASPYAVAAAAVTGEITHP 428
[46][TOP]
>UniRef100_Q6B920 3-isopropylmalate dehydratase large subunit n=1 Tax=Gracilaria
tenuistipitata var. liui RepID=Q6B920_GRATL
Length = 439
Score = 137 bits (344), Expect = 6e-31
Identities = 69/143 (48%), Positives = 90/143 (62%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
KIDR YIGSCTGGK+ DF AAAK+ KV + TF VPAT++V+ D+ +
Sbjct: 301 KIDRAYIGSCTGGKSSDFYAAAKILK--NHKVSIDTFGVPATREVFYDIINQKIDDI--- 355
Query: 345 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
+ +I AG PSC AC GGP DT+ R+N +STTNRNF GRMG K QIYL
Sbjct: 356 SVYEILVNAGVHMTTEPSCAACCGGPIDTFGRVNNTMSVISTTNRNFSGRMGAKSAQIYL 415
Query: 165 ASPYTAAASALTGRVADPREFLQ 97
SPY+ A++A+ G + +P+ FL+
Sbjct: 416 GSPYSVASTAIAGHITNPKIFLK 438
[47][TOP]
>UniRef100_A0RXN9 3-isopropylmalate dehydratase large subunit n=1 Tax=Cenarchaeum
symbiosum RepID=A0RXN9_CENSY
Length = 429
Score = 118 bits (295), Expect = 3e-25
Identities = 66/141 (46%), Positives = 87/141 (61%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
V++D+ YIGSCTG K ED AAA++ GRKV++ T ++PA ++ + G
Sbjct: 301 VELDKAYIGSCTGAKMEDLEAAARILK--GRKVRIRTEVLPAAISIYRKAVERGLVG--- 355
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
IF +AG T P+CGAC G L + +VC+STTNRNFPGRMG E Q Y
Sbjct: 356 -----IFLDAGA-TVGPPTCGACCGAHMGV---LGKGEVCISTTNRNFPGRMGDIESQTY 406
Query: 168 LASPYTAAASALTGRVADPRE 106
LASP AAASA+TG++ DPR+
Sbjct: 407 LASPLVAAASAVTGKITDPRD 427
[48][TOP]
>UniRef100_B3TBB7 Putative aconitase family (Aconitate hydratase) n=1 Tax=uncultured
marine crenarchaeote HF4000_APKG8O8 RepID=B3TBB7_9ARCH
Length = 423
Score = 117 bits (293), Expect = 5e-25
Identities = 67/141 (47%), Positives = 87/141 (61%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
++ID+ YIGSCTG K ED +A A++ GRKVKV T +VPA ++ A
Sbjct: 296 IEIDKSYIGSCTGAKYEDLVAVARILK--GRKVKVRTEVVPAAISIYKK--------ASE 345
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+IF +AG A P+CGAC G A+ +VCVSTTNRNFPGRMGH + + Y
Sbjct: 346 NGLDKIFLDAGAVIGA-PTCGACCGAHMGVLAK---DEVCVSTTNRNFPGRMGHVDSKTY 401
Query: 168 LASPYTAAASALTGRVADPRE 106
L SP AAASA+TG++ DPR+
Sbjct: 402 LTSPLVAAASAVTGKLTDPRD 422
[49][TOP]
>UniRef100_B3TAM8 Putative aconitase family (Aconitate hydratase) n=1 Tax=uncultured
marine crenarchaeote HF4000_APKG8G2 RepID=B3TAM8_9ARCH
Length = 423
Score = 116 bits (291), Expect = 9e-25
Identities = 65/141 (46%), Positives = 85/141 (60%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+++D+ YIGSCTG K ED A AK+ G+KVK+ T ++PA ++ A
Sbjct: 296 IELDKSYIGSCTGAKYEDLEAVAKILK--GKKVKIRTEILPAAISIYKK--------ATE 345
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
QIF +AG P+CGAC G A+ +VCVSTTNRNFPGRMGH E + Y
Sbjct: 346 NGLTQIFIDAGA-VVGPPTCGACCGAHMGVLAK---DEVCVSTTNRNFPGRMGHVESKTY 401
Query: 168 LASPYTAAASALTGRVADPRE 106
L SP AAASA+TG++ DPR+
Sbjct: 402 LTSPLVAAASAVTGKLTDPRD 422
[50][TOP]
>UniRef100_B3T9D1 Putative aconitase family (Aconitate hydratase) n=1 Tax=uncultured
marine crenarchaeote HF4000_APKG6J21 RepID=B3T9D1_9ARCH
Length = 423
Score = 116 bits (291), Expect = 9e-25
Identities = 65/141 (46%), Positives = 85/141 (60%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+++D+ YIGSCTG K ED A AK+ G+KVK+ T ++PA ++ A
Sbjct: 296 IELDKSYIGSCTGAKYEDLEAVAKILK--GKKVKIRTEILPAAISIYKK--------ATE 345
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
QIF +AG P+CGAC G A+ +VCVSTTNRNFPGRMGH E + Y
Sbjct: 346 NGLTQIFIDAGA-VVGPPTCGACCGAHMGVLAK---DEVCVSTTNRNFPGRMGHVESKTY 401
Query: 168 LASPYTAAASALTGRVADPRE 106
L SP AAASA+TG++ DPR+
Sbjct: 402 LTSPLVAAASAVTGKLTDPRD 422
[51][TOP]
>UniRef100_B3T8D2 Putative aconitase family (Aconitate hydratase) n=1 Tax=uncultured
marine crenarchaeote HF4000_APKG5E24 RepID=B3T8D2_9ARCH
Length = 423
Score = 116 bits (291), Expect = 9e-25
Identities = 65/141 (46%), Positives = 85/141 (60%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+++D+ YIGSCTG K ED A AK+ G+KVK+ T ++PA ++ A
Sbjct: 296 IELDKSYIGSCTGAKYEDLEAVAKILK--GKKVKIRTEILPAAISIYKK--------ATE 345
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
QIF +AG P+CGAC G A+ +VCVSTTNRNFPGRMGH E + Y
Sbjct: 346 NGLTQIFIDAGA-VVGPPTCGACCGAHMGVLAK---DEVCVSTTNRNFPGRMGHVESKTY 401
Query: 168 LASPYTAAASALTGRVADPRE 106
L SP AAASA+TG++ DPR+
Sbjct: 402 LTSPLVAAASAVTGKLTDPRD 422
[52][TOP]
>UniRef100_C0EDN6 Putative uncharacterized protein n=1 Tax=Clostridium methylpentosum
DSM 5476 RepID=C0EDN6_9CLOT
Length = 421
Score = 115 bits (287), Expect = 3e-24
Identities = 63/144 (43%), Positives = 85/144 (59%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKID+V IGSCT G+ D AAK+ V ++PATQK++++ L
Sbjct: 289 DVKIDQVVIGSCTNGRLSDIAVAAKILEGKQVAKHVRAIVIPATQKIYLEALKLGY---- 344
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ F +AGC ++P+CG CLGG A + VSTTNRNF GRMGH E ++
Sbjct: 345 ----LETFVKAGC-VVSTPTCGPCLGGHMGILAA---GERAVSTTNRNFVGRMGHVESEV 396
Query: 171 YLASPYTAAASALTGRVADPREFL 100
YLASP AAASA+TG+++ P E +
Sbjct: 397 YLASPEVAAASAVTGKISSPEEIM 420
[53][TOP]
>UniRef100_A9A5B7 3-isopropylmalate dehydratase n=1 Tax=Nitrosopumilus maritimus SCM1
RepID=A9A5B7_NITMS
Length = 422
Score = 115 bits (287), Expect = 3e-24
Identities = 64/141 (45%), Positives = 87/141 (61%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
V++D+ YIGSCTG K ED AAAK+ G+ VK+ T ++PA+ ++ A
Sbjct: 295 VELDKSYIGSCTGAKYEDLEAAAKILK--GKTVKIRTEILPASISIYKR--------AME 344
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
IF +AG T P+CGAC G A+ ++C+STTNRNFPGRMGH E + Y
Sbjct: 345 NGLLTIFLDAGV-TVGPPTCGACCGAHMGVLAK---NEICISTTNRNFPGRMGHVESETY 400
Query: 168 LASPYTAAASALTGRVADPRE 106
L+SP AAASA+TG++ DPR+
Sbjct: 401 LSSPMVAAASAVTGKITDPRD 421
[54][TOP]
>UniRef100_C4ZBK5 3-isopropylmalate dehydratase, large subunit n=1 Tax=Eubacterium
rectale ATCC 33656 RepID=C4ZBK5_EUBR3
Length = 420
Score = 114 bits (285), Expect = 4e-24
Identities = 65/146 (44%), Positives = 92/146 (63%), Gaps = 2/146 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
DVKID+V IGSCT G+ +D AAK+ G+KV + ++PATQK+++
Sbjct: 289 DVKIDQVVIGSCTNGRMDDLRIAAKILE--GKKVADGIRVIVIPATQKIYLQ-------- 338
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
A + + F EAG ++P+CG CLGG A E + CVSTTNRNF GRMGH +
Sbjct: 339 AMEEGLLKTFIEAGAIV-STPTCGPCLGGYMGVLA---EGERCVSTTNRNFVGRMGHVDS 394
Query: 177 QIYLASPYTAAASALTGRVADPREFL 100
++YLASP AAASA+TG+++ P++ +
Sbjct: 395 EVYLASPAVAAASAITGKISGPKDVM 420
[55][TOP]
>UniRef100_C7GFH7 3-isopropylmalate dehydratase, large subunit n=1 Tax=Roseburia
intestinalis L1-82 RepID=C7GFH7_9FIRM
Length = 420
Score = 113 bits (283), Expect = 7e-24
Identities = 67/144 (46%), Positives = 90/144 (62%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
D+KID+V IGSCT G+ +D AA + G+KV + ++PATQK+++D
Sbjct: 289 DIKIDQVVIGSCTNGRMDDLRVAASILK--GKKVAKGLRVIVIPATQKIYLD-------- 338
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
A + + F EAG ++P+CG CLGG A E + CVSTTNRNF GRMGH E
Sbjct: 339 AMEEGLLKTFIEAGA-VVSTPTCGPCLGGYMGILA---EHERCVSTTNRNFVGRMGHVES 394
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
+IYLASP AAASA+TG+++ P E
Sbjct: 395 EIYLASPAVAAASAITGKLSGPDE 418
[56][TOP]
>UniRef100_UPI0001966B48 hypothetical protein SUBVAR_01587 n=1 Tax=Subdoligranulum variabile
DSM 15176 RepID=UPI0001966B48
Length = 419
Score = 113 bits (282), Expect = 1e-23
Identities = 63/142 (44%), Positives = 84/142 (59%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
D+KID++ IGSCT G+ ED AA ++ V ++PAT V+ +
Sbjct: 289 DIKIDQIVIGSCTNGRIEDMQAAYEILKGKHIAKGVRGIIIPATMAVYKECIL------- 341
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ + F +AGC ++P+CG CLGG A + CVSTTNRNF GRMGH + ++
Sbjct: 342 -RGYTEAFIDAGCIV-STPTCGPCLGGYMGILAA---GERCVSTTNRNFVGRMGHVDSEV 396
Query: 171 YLASPYTAAASALTGRVADPRE 106
YLASP TAAASALTG + DPRE
Sbjct: 397 YLASPATAAASALTGYITDPRE 418
[57][TOP]
>UniRef100_C3WDK0 Homoaconitate hydratase n=1 Tax=Fusobacterium mortiferum ATCC 9817
RepID=C3WDK0_FUSMR
Length = 424
Score = 113 bits (282), Expect = 1e-23
Identities = 68/151 (45%), Positives = 91/151 (60%), Gaps = 7/151 (4%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPGA 355
VKID+ YIGSCTGG+ D AA + GRK+ V + PA+++VW
Sbjct: 291 VKIDQAYIGSCTGGRYNDLKLAADILK--GRKIAEGVRLLISPASKEVW----------- 337
Query: 354 GGKTCA-----QIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMG 190
+ CA Q EAG AS SCGACLG + + E +VC+S+TNRNF GRMG
Sbjct: 338 --ERCAKDGILQTLSEAGATVLAS-SCGACLGIHSGA---IGEGEVCISSTNRNFIGRMG 391
Query: 189 HKEGQIYLASPYTAAASALTGRVADPREFLQ 97
K+G++YLASP + AA+ALTG + DPR+F++
Sbjct: 392 SKKGEVYLASPLSVAAAALTGYIVDPRKFIE 422
[58][TOP]
>UniRef100_C7II84 3-isopropylmalate dehydratase, large subunit n=1 Tax=Clostridium
papyrosolvens DSM 2782 RepID=C7II84_9CLOT
Length = 419
Score = 112 bits (281), Expect = 1e-23
Identities = 63/142 (44%), Positives = 83/142 (58%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
D+KID+V IGSCT G+ ED AA++ V ++PATQK+W A
Sbjct: 289 DIKIDQVVIGSCTNGRIEDMRIAAQILKGQKVSDNVRCIIIPATQKIWKQ--------AM 340
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ IF +AG ++P+CG CLGG A+ + V+TTNRNF GRMGH E ++
Sbjct: 341 NEGLFDIFIDAGAAV-STPTCGPCLGGHMGILAK---GERAVATTNRNFVGRMGHPESEV 396
Query: 171 YLASPYTAAASALTGRVADPRE 106
YLASP AAASA+ GR+A P E
Sbjct: 397 YLASPAVAAASAIAGRIAGPDE 418
[59][TOP]
>UniRef100_C4FRW1 Putative uncharacterized protein n=1 Tax=Veillonella dispar ATCC
17748 RepID=C4FRW1_9FIRM
Length = 419
Score = 112 bits (280), Expect = 2e-23
Identities = 69/144 (47%), Positives = 89/144 (61%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
D+KID+V IGSCT G+ ED +AAA++F GRKV V ++P +Q DVY +
Sbjct: 289 DIKIDQVIIGSCTNGRYEDLVAAAEIFK--GRKVAPFVRCIVIPGSQ----DVYDQAMKD 342
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
IF +A C ++P+CG CLGG A E + VSTTNRNF GRMGH +
Sbjct: 343 G----LLDIFIQADCAV-STPTCGPCLGGYMGIMA---EGERTVSTTNRNFRGRMGHVDS 394
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
++YLASPY AAASA+ GR+A P E
Sbjct: 395 EVYLASPYVAAASAVLGRIAGPEE 418
[60][TOP]
>UniRef100_C0V4R3 3-isopropylmalate dehydratase, large subunit n=1 Tax=Veillonella
parvula DSM 2008 RepID=C0V4R3_9FIRM
Length = 419
Score = 112 bits (280), Expect = 2e-23
Identities = 69/144 (47%), Positives = 89/144 (61%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
D+KID+V IGSCT G+ ED +AAA++F GRKV V ++P +Q DVY +
Sbjct: 289 DIKIDQVIIGSCTNGRYEDLVAAAEIFK--GRKVAPFVRCIVIPGSQ----DVYDQAMKD 342
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
IF +A C ++P+CG CLGG A E + VSTTNRNF GRMGH +
Sbjct: 343 G----LLDIFIQADCAV-STPTCGPCLGGYMGIMA---EGERTVSTTNRNFRGRMGHVDS 394
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
++YLASPY AAASA+ GR+A P E
Sbjct: 395 EVYLASPYVAAASAVLGRIAGPEE 418
[61][TOP]
>UniRef100_C6PQI2 3-isopropylmalate dehydratase, large subunit n=1 Tax=Clostridium
carboxidivorans P7 RepID=C6PQI2_9CLOT
Length = 421
Score = 112 bits (279), Expect = 2e-23
Identities = 61/142 (42%), Positives = 86/142 (60%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
+V ID+ IGSCT G+ ED AAAK+F +V + PATQK++++
Sbjct: 289 EVFIDQAVIGSCTNGRIEDLRAAAKVFKGNKVNKRVRAIIFPATQKIYLEALR------- 341
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ +IF EAG ++P+CG CLGG A+ + ++TTNRNF GRMGH E ++
Sbjct: 342 -EGLLEIFIEAGA-VVSTPTCGPCLGGHMGILAK---GERAIATTNRNFVGRMGHPESEV 396
Query: 171 YLASPYTAAASALTGRVADPRE 106
YLASP AAASA+TG+++ P E
Sbjct: 397 YLASPAVAAASAITGKISSPEE 418
[62][TOP]
>UniRef100_C6LJ75 3-isopropylmalate dehydratase, large subunit n=1 Tax=Bryantella
formatexigens DSM 14469 RepID=C6LJ75_9FIRM
Length = 422
Score = 112 bits (279), Expect = 2e-23
Identities = 67/144 (46%), Positives = 88/144 (61%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
DV ID+ IGSCT G+ +D AAK+ GRKVK V ++PATQKV++
Sbjct: 290 DVVIDQAVIGSCTNGRIDDLRCAAKILE--GRKVKKGVRCIVIPATQKVYLQ-------- 339
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
A + + F EAG ++P+CG CLGG A E + C+STTNRNF GRMGH
Sbjct: 340 AMEEGLLKTFIEAGA-VVSTPTCGPCLGGYMGILA---EGERCISTTNRNFVGRMGHVNS 395
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
++YLASP AAASA+TG+++ P E
Sbjct: 396 EVYLASPAVAAASAVTGKISAPAE 419
[63][TOP]
>UniRef100_C0FYL9 Putative uncharacterized protein n=1 Tax=Roseburia inulinivorans
DSM 16841 RepID=C0FYL9_9FIRM
Length = 436
Score = 111 bits (278), Expect = 3e-23
Identities = 65/146 (44%), Positives = 90/146 (61%), Gaps = 2/146 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
DVKID+V IGSCT G+ +D AA + G+KVK + ++PATQK+++
Sbjct: 305 DVKIDQVVIGSCTNGRMDDLRIAASVLK--GKKVKKGLRVIVIPATQKIYLQ-------- 354
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
A + + F EAG ++P+CG CLGG A + CVSTTNRNF GRMGH +
Sbjct: 355 AMEEGLLRTFIEAGA-VVSTPTCGPCLGGYMGILAA---GERCVSTTNRNFVGRMGHVDS 410
Query: 177 QIYLASPYTAAASALTGRVADPREFL 100
++YLASP AAASA+TG+++ P E +
Sbjct: 411 EVYLASPAVAAASAITGKISSPEEVM 436
[64][TOP]
>UniRef100_C7H4B6 3-isopropylmalate dehydratase, large subunit n=1
Tax=Faecalibacterium prausnitzii A2-165
RepID=C7H4B6_9FIRM
Length = 419
Score = 111 bits (277), Expect = 4e-23
Identities = 63/141 (44%), Positives = 83/141 (58%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
D++ID+V IGSCT G+ ED AA + V ++PAT V+ +
Sbjct: 289 DIRIDQVVIGSCTNGRLEDMEAAYNILKGKHIAKGVRGIIIPATMAVYKECIL------- 341
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ + F +AGC ++P+CG CLGG A E + CVSTTNRNF GRMGH + ++
Sbjct: 342 -RGWTEAFIDAGCIV-STPTCGPCLGGYMGILA---EGERCVSTTNRNFVGRMGHVKSEV 396
Query: 171 YLASPYTAAASALTGRVADPR 109
YLASP TAAASALTG + DPR
Sbjct: 397 YLASPATAAASALTGYITDPR 417
[65][TOP]
>UniRef100_A8UWH6 3-isopropylmalate dehydratase n=1 Tax=Hydrogenivirga sp. 128-5-R1-1
RepID=A8UWH6_9AQUI
Length = 432
Score = 111 bits (277), Expect = 4e-23
Identities = 64/149 (42%), Positives = 89/149 (59%), Gaps = 5/149 (3%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAA---GRKVK--VPTFLVPATQKVWMDVYALPV 364
+ +D+ +IGSCT G+ ED AAK+F +A G+KV V ++PA++ V+M
Sbjct: 289 INVDQAFIGSCTNGRIEDLRIAAKVFESALKQGKKVHPYVRCIVIPASKNVYMQ------ 342
Query: 363 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 184
A + IF EAGC S +CG CLGG A E + C+ST+NRNFPGRMGH
Sbjct: 343 --AMKEGLIDIFMEAGCAVSTS-TCGPCLGGHMGVLA---EGERCISTSNRNFPGRMGHP 396
Query: 183 EGQIYLASPYTAAASALTGRVADPREFLQ 97
+ + YLA+P AASA+ GR+A P E ++
Sbjct: 397 KSESYLANPAVVAASAVLGRIAHPEEVVR 425
[66][TOP]
>UniRef100_B8I4G0 3-isopropylmalate dehydratase, large subunit n=1 Tax=Clostridium
cellulolyticum H10 RepID=B8I4G0_CLOCE
Length = 419
Score = 110 bits (275), Expect = 6e-23
Identities = 66/144 (45%), Positives = 85/144 (59%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
D+KID+V IGSCT G+ ED AA + GRKV V ++PATQK+W
Sbjct: 289 DIKIDQVVIGSCTNGRIEDMRIAAGVLK--GRKVSDNVRCIIIPATQKIWKQ-------- 338
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
A + IF +AG ++P+CG CLGG A+ + V+TTNRNF GRMGH E
Sbjct: 339 AMNEGLFDIFIDAGAAV-STPTCGPCLGGHMGILAK---GERAVATTNRNFVGRMGHPES 394
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
++YLA P AAASA+ GR+A P E
Sbjct: 395 EVYLAGPAVAAASAVAGRIAGPDE 418
[67][TOP]
>UniRef100_A0B7A3 3-isopropylmalate dehydratase, large subunit n=1 Tax=Methanosaeta
thermophila PT RepID=A0B7A3_METTP
Length = 382
Score = 110 bits (275), Expect = 6e-23
Identities = 58/141 (41%), Positives = 91/141 (64%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+++D+V+IG+CT G+ ED AA++ G++VK+ T ++PA++++++ GA
Sbjct: 256 IEVDQVFIGTCTNGRLEDLEMAARI--VKGKRVKIRTLVIPASREIYL--------GALR 305
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ EAG P CG CLG L + +VC+ST+NRNFPGRMG + G++Y
Sbjct: 306 SGVIETLVEAGAMI-GPPGCGPCLGAHMGV---LGDGEVCLSTSNRNFPGRMG-RNGKVY 360
Query: 168 LASPYTAAASALTGRVADPRE 106
LASP TAAA+A+TG++ DPR+
Sbjct: 361 LASPATAAATAITGKITDPRD 381
[68][TOP]
>UniRef100_A6TTR7 3-isopropylmalate dehydratase, large subunit n=1 Tax=Alkaliphilus
metalliredigens QYMF RepID=A6TTR7_ALKMQ
Length = 420
Score = 110 bits (274), Expect = 8e-23
Identities = 60/144 (41%), Positives = 87/144 (60%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKID+V IGSCT G+ +D AAK+ V + PATQK+++D A
Sbjct: 289 DVKIDQVVIGSCTNGRIQDLRMAAKVMEGKQVAKGVRVIVFPATQKIYLD--------AM 340
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ + F +AG ++P+CG CLGG A+ + ++TTNRNF GRMGH E ++
Sbjct: 341 KEGLLETFIKAGA-VVSTPTCGPCLGGHMGVLAK---GERAIATTNRNFVGRMGHPESEV 396
Query: 171 YLASPYTAAASALTGRVADPREFL 100
YLASP AAASA+TG++ +P++ +
Sbjct: 397 YLASPAVAAASAITGKITNPKDIV 420
[69][TOP]
>UniRef100_C0CLF7 Putative uncharacterized protein n=1 Tax=Blautia hydrogenotrophica
DSM 10507 RepID=C0CLF7_9FIRM
Length = 422
Score = 110 bits (274), Expect = 8e-23
Identities = 65/144 (45%), Positives = 89/144 (61%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
DV ID+ IGSCT G+ ED AA++ GRKVK + ++PATQ +++
Sbjct: 290 DVVIDQSVIGSCTNGRMEDLRIAAEILK--GRKVKKGIRCIVIPATQAIYLQ-------- 339
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
A + +IF EAG ++P+CG CLGG A E + C+STTNRNF GRMGH +
Sbjct: 340 AMKEGLLEIFIEAGA-VVSTPTCGPCLGGYMGILA---EGERCISTTNRNFVGRMGHVDS 395
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
++YLASP AAASA+TG+++ P E
Sbjct: 396 EVYLASPAVAAASAVTGKISAPAE 419
[70][TOP]
>UniRef100_A8S7H1 Putative uncharacterized protein n=1 Tax=Faecalibacterium
prausnitzii M21/2 RepID=A8S7H1_9FIRM
Length = 419
Score = 110 bits (274), Expect = 8e-23
Identities = 66/141 (46%), Positives = 83/141 (58%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
D+KID+V IGSCT G+ ED AA + V ++PAT V+ +
Sbjct: 289 DIKIDQVVIGSCTNGRLEDMEAAYNILKGKHIAKGVRGIIIPATMAVYKECILR------ 342
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
G T A F +AGC ++P+CG CLGG A + CVSTTNRNF GRMGH + ++
Sbjct: 343 GWTTA--FIDAGCIV-STPTCGPCLGGYMGILAA---GERCVSTTNRNFVGRMGHVDSEV 396
Query: 171 YLASPYTAAASALTGRVADPR 109
YLASP TAAASALTG + DPR
Sbjct: 397 YLASPATAAASALTGYITDPR 417
[71][TOP]
>UniRef100_A3DHI4 3-isopropylmalate dehydratase large subunit n=3 Tax=Clostridium
thermocellum RepID=LEUC_CLOTH
Length = 419
Score = 110 bits (274), Expect = 8e-23
Identities = 66/144 (45%), Positives = 86/144 (59%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
++KID+V IGSCT G+ ED AA++ GRKV V ++PATQK+W
Sbjct: 289 NIKIDQVVIGSCTNGRIEDLRVAAEVLK--GRKVHKDVRCIIIPATQKIWKQ-------- 338
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
A + IF +AG ++P+CG CLGG A+ + V+TTNRNF GRMGH E
Sbjct: 339 AMNEGLFDIFIDAGAAV-STPTCGPCLGGHMGILAK---GERAVATTNRNFVGRMGHPES 394
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
+IYLASP AAASA+ GR+ P E
Sbjct: 395 EIYLASPAVAAASAVLGRIGSPDE 418
[72][TOP]
>UniRef100_Q3ZZK0 Homoaconitate hydratase family protein n=1 Tax=Dehalococcoides sp.
CBDB1 RepID=Q3ZZK0_DEHSC
Length = 417
Score = 109 bits (273), Expect = 1e-22
Identities = 60/142 (42%), Positives = 85/142 (59%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
K+D+V+IG+CTGG+ +D AA +F R + + PA+QK++++ L
Sbjct: 288 KLDQVFIGTCTGGRLDDLAVAAAIFKNRKRHPQTRLIVTPASQKIYLEAIRLGY------ 341
Query: 345 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
+I +AG + P CGACLG L + +VC+ST NRNF GRMG+ EG IYL
Sbjct: 342 --IEILVQAGANI-MPPGCGACLGVHQGV---LGDGEVCLSTANRNFKGRMGNPEGFIYL 395
Query: 165 ASPYTAAASALTGRVADPREFL 100
AS TAAASA+ G ++DPRE +
Sbjct: 396 ASAATAAASAIKGEISDPREVM 417
[73][TOP]
>UniRef100_A5FS15 3-isopropylmalate dehydratase, large subunit n=1
Tax=Dehalococcoides sp. BAV1 RepID=A5FS15_DEHSB
Length = 431
Score = 109 bits (273), Expect = 1e-22
Identities = 60/142 (42%), Positives = 85/142 (59%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
K+D+V+IG+CTGG+ +D AA +F R + + PA+QK++++ L
Sbjct: 302 KLDQVFIGTCTGGRLDDLAVAAAIFKNRKRHPQTRLIVTPASQKIYLEAIRLGY------ 355
Query: 345 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
+I +AG + P CGACLG L + +VC+ST NRNF GRMG+ EG IYL
Sbjct: 356 --IEILVQAGANI-MPPGCGACLGVHQGV---LGDGEVCLSTANRNFKGRMGNPEGFIYL 409
Query: 165 ASPYTAAASALTGRVADPREFL 100
AS TAAASA+ G ++DPRE +
Sbjct: 410 ASAATAAASAIKGEISDPREVM 431
[74][TOP]
>UniRef100_Q0QLE2 2,3-dimethylmalate dehydratase large subunit n=1 Tax=Eubacterium
barkeri RepID=Q0QLE2_EUBBA
Length = 420
Score = 109 bits (273), Expect = 1e-22
Identities = 66/141 (46%), Positives = 84/141 (59%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
V ID+V IGSCT G+ ED AA + K V ++PAT K+++D AG
Sbjct: 291 VTIDQVVIGSCTNGRFEDLKRAADILRGKHVKKGVRMLVIPATHKIYLDAME-----AG- 344
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ F EAG T ++P+CG CLGG A E + CVSTTNRNF GRMGH + ++Y
Sbjct: 345 --YLREFIEAGA-TISTPTCGPCLGGYMGILA---EGERCVSTTNRNFVGRMGHVDSEVY 398
Query: 168 LASPYTAAASALTGRVADPRE 106
LASP AAASA+ GR+A P E
Sbjct: 399 LASPEVAAASAILGRIATPDE 419
[75][TOP]
>UniRef100_C0FIT9 Putative uncharacterized protein n=1 Tax=Clostridium sp. M62/1
RepID=C0FIT9_9CLOT
Length = 278
Score = 109 bits (272), Expect = 1e-22
Identities = 65/146 (44%), Positives = 88/146 (60%), Gaps = 2/146 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
DV ID+V IGSCT G+ ED AA++ GRKVK V ++PATQ +++
Sbjct: 146 DVAIDQVVIGSCTNGRLEDMRIAAEILK--GRKVKKGVRCIVIPATQAIYLQCIK----- 198
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
+ + F EAG ++P+CG CLGG A + CVSTTNRNF GRMGH +
Sbjct: 199 ---EGLMETFIEAGA-VVSTPTCGPCLGGYMGILAA---GERCVSTTNRNFVGRMGHVDS 251
Query: 177 QIYLASPYTAAASALTGRVADPREFL 100
++YLASP AAASA+TG+++ P E +
Sbjct: 252 EVYLASPAVAAASAVTGKISSPCEIM 277
[76][TOP]
>UniRef100_Q8TVF2 3-isopropylmalate dehydratase large subunit 1 n=1 Tax=Methanopyrus
kandleri RepID=LEUC1_METKA
Length = 418
Score = 109 bits (272), Expect = 1e-22
Identities = 60/143 (41%), Positives = 84/143 (58%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+ ID+V+IGSCT G+ ED AA++ V ++PA+++V+ V
Sbjct: 288 IAIDQVFIGSCTNGRYEDLKVAAEVLEGEEVHDDVRLIVIPASREVYHRTLKDGV----- 342
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
++ EAG P+CG CLGG A E + CV+T+NRNFPGRMGH+E ++Y
Sbjct: 343 ---LEVLHEAGA-LICPPNCGPCLGGHMGVLA---EGERCVATSNRNFPGRMGHRESEVY 395
Query: 168 LASPYTAAASALTGRVADPREFL 100
LASP TAAASA+ G + DPR +L
Sbjct: 396 LASPATAAASAIEGEITDPRPYL 418
[77][TOP]
>UniRef100_UPI000196B289 hypothetical protein CATMIT_00953 n=1 Tax=Catenibacterium mitsuokai
DSM 15897 RepID=UPI000196B289
Length = 425
Score = 108 bits (271), Expect = 2e-22
Identities = 66/144 (45%), Positives = 85/144 (59%), Gaps = 2/144 (1%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKV--KVPTFLVPATQKVWMDVYALPVPGA 355
+ ID+V IGSCT G+ ED AA + G+KV V +VPATQK+++ +
Sbjct: 292 IYIDQVVIGSCTNGRMEDLRKAAAILK--GKKVADNVRVMVVPATQKIYLQCILEGI--- 346
Query: 354 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 175
+ F EAGC +PSCG C+GG A+ + CVSTTNRNF GRMG E
Sbjct: 347 -----LETFVEAGCAVN-TPSCGPCMGGHMGVLAK---GEKCVSTTNRNFVGRMGDVESL 397
Query: 174 IYLASPYTAAASALTGRVADPREF 103
IYLASP TAAASA+ G +A+P +F
Sbjct: 398 IYLASPETAAASAIAGYIANPEKF 421
[78][TOP]
>UniRef100_C6E531 Homoaconitate hydratase family protein n=1 Tax=Geobacter sp. M21
RepID=C6E531_GEOSM
Length = 427
Score = 108 bits (271), Expect = 2e-22
Identities = 65/143 (45%), Positives = 86/143 (60%), Gaps = 1/143 (0%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
++D+VY+GSCT G+ ED AA++ V L PAT +++ D A +
Sbjct: 299 QVDQVYLGSCTNGRLEDLRVAAQILKGKKIASHVRAILSPATPQIYKDAVA--------E 350
Query: 345 TCAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
QIF +AG C T +P+CGACLG A E +VC STTNRNF GRMG K G ++
Sbjct: 351 GLIQIFMDAGFCVT--NPTCGACLGMSNGVLA---EGEVCASTTNRNFMGRMG-KGGMVH 404
Query: 168 LASPYTAAASALTGRVADPREFL 100
L SP TAAASA+ G++ADPR +L
Sbjct: 405 LLSPATAAASAIEGKIADPRNYL 427
[79][TOP]
>UniRef100_B9KB94 3-isopropylmalate dehydratase large subunit 2 n=1 Tax=Thermotoga
neapolitana DSM 4359 RepID=B9KB94_THENN
Length = 417
Score = 108 bits (271), Expect = 2e-22
Identities = 60/141 (42%), Positives = 82/141 (58%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KID+V IGSCT G+ ED AA++ V ++P +QKV+
Sbjct: 288 IKIDQVVIGSCTNGRIEDLRLAAQILKGRTVSPNVRCIIIPGSQKVYKQALK-------- 339
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ IF +AGC ++P+CG CLGG A E ++ VSTTNRNF GRMGH +++
Sbjct: 340 EGLIDIFLDAGCAV-STPTCGPCLGGHMGVLA---EGEIAVSTTNRNFVGRMGHPNSKVF 395
Query: 168 LASPYTAAASALTGRVADPRE 106
LASP AAASA+ G +ADPR+
Sbjct: 396 LASPAVAAASAVKGYIADPRK 416
[80][TOP]
>UniRef100_C4GAI7 Putative uncharacterized protein n=1 Tax=Shuttleworthia satelles
DSM 14600 RepID=C4GAI7_9FIRM
Length = 434
Score = 108 bits (271), Expect = 2e-22
Identities = 66/146 (45%), Positives = 90/146 (61%), Gaps = 2/146 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKV--KVPTFLVPATQKVWMDVYALPVPG 358
D+ ID+V IGSCT G+ D AAA++ GRKV +V T ++PATQ++++D
Sbjct: 303 DIAIDQVVIGSCTNGRLSDLKAAAEILK--GRKVADRVRTIIIPATQQIYLDAMQ----- 355
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
AG + F EAG ++P+CG CLGG A + CVSTTNRNF GRMG
Sbjct: 356 AG---YLKTFIEAGA-VVSTPTCGPCLGGYMGILAA---GERCVSTTNRNFVGRMGDVTS 408
Query: 177 QIYLASPYTAAASALTGRVADPREFL 100
++YLASP AAASA+TGR++ P + +
Sbjct: 409 EVYLASPAVAAASAVTGRISGPADLI 434
[81][TOP]
>UniRef100_B0PBC0 Putative uncharacterized protein n=1 Tax=Anaerotruncus colihominis
DSM 17241 RepID=B0PBC0_9FIRM
Length = 419
Score = 108 bits (271), Expect = 2e-22
Identities = 65/142 (45%), Positives = 89/142 (62%), Gaps = 2/142 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
DV+ID+V IGSCT G+ D AAA+L +G+KV V ++P TQ+++ +
Sbjct: 289 DVRIDQVVIGSCTNGRIGDLAAAARLM--SGKKVADGVRCIVIPGTQQIYREAIH----- 341
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
AG F +AGC ++P+CG CLGG A E + CV+TTNRNF GRMGH +
Sbjct: 342 AG---YIDTFLDAGCAV-STPTCGPCLGGYMGILA---EGERCVATTNRNFVGRMGHVKS 394
Query: 177 QIYLASPYTAAASALTGRVADP 112
++YLASP AAASA+ G++ADP
Sbjct: 395 EVYLASPAVAAASAIRGKIADP 416
[82][TOP]
>UniRef100_B5EHU2 3-isopropylmalate dehydratase large subunit n=1 Tax=Geobacter
bemidjiensis Bem RepID=LEUC_GEOBB
Length = 427
Score = 108 bits (271), Expect = 2e-22
Identities = 65/143 (45%), Positives = 86/143 (60%), Gaps = 1/143 (0%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
++D+VY+GSCT G+ ED AA++ V L PAT +++ D A +
Sbjct: 299 QVDQVYLGSCTNGRLEDLRVAAQILKGKKIASHVRAILSPATPQIYKDAVA--------E 350
Query: 345 TCAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
QIF +AG C T +P+CGACLG A E +VC STTNRNF GRMG K G ++
Sbjct: 351 GLIQIFMDAGFCVT--NPTCGACLGMSNGVLA---EGEVCASTTNRNFMGRMG-KGGMVH 404
Query: 168 LASPYTAAASALTGRVADPREFL 100
L SP TAAASA+ G++ADPR +L
Sbjct: 405 LLSPATAAASAIEGKIADPRNYL 427
[83][TOP]
>UniRef100_Q3Z9A7 Homoaconitate hydratase family protein n=1 Tax=Dehalococcoides
ethenogenes 195 RepID=Q3Z9A7_DEHE1
Length = 417
Score = 108 bits (270), Expect = 2e-22
Identities = 60/142 (42%), Positives = 84/142 (59%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
K+D+V+IG+CTGG+ +D AA +F + + PA+QKV+++ L
Sbjct: 288 KLDQVFIGTCTGGRLDDLAVAAAIFKNRRHHPQTRLIVTPASQKVYLEAIRLGY------ 341
Query: 345 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
+I +AG + P CGACLG L + +VC+ST NRNF GRMG+ EG IYL
Sbjct: 342 --IEILVQAGANV-MPPGCGACLGVHQGV---LGDGEVCLSTANRNFKGRMGNPEGFIYL 395
Query: 165 ASPYTAAASALTGRVADPREFL 100
AS TAAASA+ G ++DPRE +
Sbjct: 396 ASAATAAASAIKGEISDPREVM 417
[84][TOP]
>UniRef100_B9E370 Putative uncharacterized protein n=1 Tax=Clostridium kluyveri NBRC
12016 RepID=B9E370_CLOK1
Length = 426
Score = 108 bits (270), Expect = 2e-22
Identities = 64/144 (44%), Positives = 88/144 (61%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
++KID+V IGSCT G+ D AAK+ GRKV V T + PATQ +++
Sbjct: 295 EIKIDQVVIGSCTNGRIGDLRVAAKVLK--GRKVNSNVRTIIFPATQSIYLQ-------- 344
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
A + +IF E+G ++P+CG CLGG A+ + V+TTNRNF GRMGH E
Sbjct: 345 AMKEGLLEIFIESGA-VVSTPTCGPCLGGHMGILAK---GERAVATTNRNFTGRMGHVES 400
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
++YLASP AAASA+TG+++ P E
Sbjct: 401 EVYLASPAVAAASAVTGKISSPEE 424
[85][TOP]
>UniRef100_C1QEQ6 3-isopropylmalate dehydratase large subunit n=1 Tax=Brachyspira
murdochii DSM 12563 RepID=C1QEQ6_9SPIR
Length = 201
Score = 108 bits (270), Expect = 2e-22
Identities = 61/141 (43%), Positives = 81/141 (57%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
D+K+D+V IGSCT G+ D AA + V ++PATQKV+ + L
Sbjct: 73 DIKVDQVVIGSCTNGRLSDMATAANILKGKKIAKNVRCIIIPATQKVYKECIKLGY---- 128
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
IF +AGC ++P+CG CLGG A +V V+TTNRNF GRMG K ++
Sbjct: 129 ----MDIFIDAGCAV-STPTCGPCLGGYMGILAH---DEVAVTTTNRNFVGRMGDKTSKV 180
Query: 171 YLASPYTAAASALTGRVADPR 109
YLASP TAA SALTG + +P+
Sbjct: 181 YLASPATAAYSALTGYITEPK 201
[86][TOP]
>UniRef100_A5MZ75 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
kluyveri DSM 555 RepID=LEUC_CLOK5
Length = 420
Score = 108 bits (270), Expect = 2e-22
Identities = 64/144 (44%), Positives = 88/144 (61%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
++KID+V IGSCT G+ D AAK+ GRKV V T + PATQ +++
Sbjct: 289 EIKIDQVVIGSCTNGRIGDLRVAAKVLK--GRKVNSNVRTIIFPATQSIYLQ-------- 338
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
A + +IF E+G ++P+CG CLGG A+ + V+TTNRNF GRMGH E
Sbjct: 339 AMKEGLLEIFIESGA-VVSTPTCGPCLGGHMGILAK---GERAVATTNRNFTGRMGHVES 394
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
++YLASP AAASA+TG+++ P E
Sbjct: 395 EVYLASPAVAAASAVTGKISSPEE 418
[87][TOP]
>UniRef100_O67078 3-isopropylmalate dehydratase large subunit n=1 Tax=Aquifex
aeolicus RepID=LEUC_AQUAE
Length = 432
Score = 108 bits (270), Expect = 2e-22
Identities = 63/149 (42%), Positives = 87/149 (58%), Gaps = 5/149 (3%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAA---GRKVK--VPTFLVPATQKVWMDVYALPV 364
+ ID+ +IGSCT G+ ED AAK+F AA G+KV V ++PA++ ++
Sbjct: 289 ITIDQAFIGSCTNGRIEDLRVAAKVFEAALKQGKKVHPYVRCIVIPASKAIYKQALK--- 345
Query: 363 PGAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHK 184
+ IF EAGC S +CG CLGG A E + C+ST+NRNFPGRMGH
Sbjct: 346 -----EGLIDIFMEAGCVVSTS-TCGPCLGGHMGVLA---EGERCISTSNRNFPGRMGHP 396
Query: 183 EGQIYLASPYTAAASALTGRVADPREFLQ 97
+ + YLA+P AASA+ GR+A P E ++
Sbjct: 397 KSESYLANPAVVAASAIMGRIAHPDEVVK 425
[88][TOP]
>UniRef100_C4EWE6 3-isopropylmalate dehydratase, large subunit n=1
Tax=Thermanaerovibrio acidaminovorans DSM 6589
RepID=C4EWE6_9BACT
Length = 417
Score = 108 bits (269), Expect = 3e-22
Identities = 65/142 (45%), Positives = 82/142 (57%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DV+I +V+IGSCT G+ ED AAK+ V L+PA+++ D+ A G
Sbjct: 286 DVEIHQVFIGSCTNGRIEDLRQAAKVLKGRRLHPSVRGVLIPASRR---DMAAAMQEGL- 341
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
++F EAG +PSCG CLGG A E +VCVST NRNF GRMGH Q+
Sbjct: 342 ----MEVFMEAGFSI-CTPSCGPCLGGHLGILA---EGEVCVSTGNRNFTGRMGHPRSQV 393
Query: 171 YLASPYTAAASALTGRVADPRE 106
YLASP AAAS + GR+ DP E
Sbjct: 394 YLASPAVAAASGVMGRIWDPSE 415
[89][TOP]
>UniRef100_A8CU07 Homoaconitate hydratase family protein n=1 Tax=Dehalococcoides sp.
VS RepID=A8CU07_9CHLR
Length = 417
Score = 108 bits (269), Expect = 3e-22
Identities = 60/142 (42%), Positives = 84/142 (59%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
K+D+V+IG+CTGG+ +D AA +F + + PA+QKV+++ L
Sbjct: 288 KLDQVFIGTCTGGRLDDLAVAAAIFKNRRHHPQTRLIVTPASQKVYLEAIRLGY------ 341
Query: 345 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
+I +AG + P CGACLG L + +VC+ST NRNF GRMG+ EG IYL
Sbjct: 342 --IEILVQAGANI-MPPGCGACLGVHQGV---LGDGEVCLSTANRNFKGRMGNPEGFIYL 395
Query: 165 ASPYTAAASALTGRVADPREFL 100
AS TAAASA+ G ++DPRE +
Sbjct: 396 ASAATAAASAIKGEISDPREVM 417
[90][TOP]
>UniRef100_C9L6F6 3-isopropylmalate dehydratase, large subunit n=1 Tax=Blautia
hansenii DSM 20583 RepID=C9L6F6_RUMHA
Length = 425
Score = 107 bits (268), Expect = 4e-22
Identities = 60/142 (42%), Positives = 84/142 (59%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DV I + IGSCT G+ +D AA++ K V ++PATQK+++
Sbjct: 293 DVIIQQSVIGSCTNGRIDDLRCAAQILKNRKVKKGVRCIIIPATQKIYLQALE------- 345
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ +IF EAG ++P+CG CLGG A E + C+STTNRNF GRMGH + ++
Sbjct: 346 -EGLLKIFIEAGA-VVSTPTCGPCLGGYMGILA---EGERCISTTNRNFVGRMGHVKSEV 400
Query: 171 YLASPYTAAASALTGRVADPRE 106
YLASP AAASA+TG+++ P E
Sbjct: 401 YLASPAVAAASAITGKISSPEE 422
[91][TOP]
>UniRef100_C6ML86 Homoaconitate hydratase family protein n=1 Tax=Geobacter sp. M18
RepID=C6ML86_9DELT
Length = 427
Score = 107 bits (268), Expect = 4e-22
Identities = 65/142 (45%), Positives = 86/142 (60%), Gaps = 1/142 (0%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKT 343
+D+VY+GSCT G+ ED AA++ V L PAT +++ D A +
Sbjct: 300 VDQVYLGSCTNGRLEDLRVAAQILKGKKIASNVRGILSPATPQIYKDAVA--------EG 351
Query: 342 CAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
QIF +AG C T +P+CGACLG A E +VC STTNRNF GRMG K G ++L
Sbjct: 352 LIQIFMDAGFCVT--NPTCGACLGMSNGVLA---EGEVCASTTNRNFMGRMG-KGGMVHL 405
Query: 165 ASPYTAAASALTGRVADPREFL 100
SP TAAASA+ G++ADPR++L
Sbjct: 406 LSPATAAASAIEGKLADPRKYL 427
[92][TOP]
>UniRef100_A6BFK8 Putative uncharacterized protein n=1 Tax=Dorea longicatena DSM
13814 RepID=A6BFK8_9FIRM
Length = 424
Score = 107 bits (268), Expect = 4e-22
Identities = 62/141 (43%), Positives = 80/141 (56%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KID+V IGSCT G+ ED AA + V +VPATQK++
Sbjct: 292 IKIDQVVIGSCTNGRMEDMRKAAAILQGHTVHPDVRVMVVPATQKIYKQCIR-------- 343
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ +IF +AGC +PSCG C+GG A + CVSTTNRNF GRMGH + IY
Sbjct: 344 EGLLEIFVDAGCAVN-TPSCGPCMGGHMGVMAA---GEKCVSTTNRNFVGRMGHVDSLIY 399
Query: 168 LASPYTAAASALTGRVADPRE 106
LASP AAASA+ G +A+P +
Sbjct: 400 LASPEVAAASAIAGYIANPEK 420
[93][TOP]
>UniRef100_A8AB09 3-isopropylmalate dehydratase, large subunit n=1 Tax=Ignicoccus
hospitalis KIN4/I RepID=A8AB09_IGNH4
Length = 419
Score = 107 bits (268), Expect = 4e-22
Identities = 64/143 (44%), Positives = 86/143 (60%), Gaps = 2/143 (1%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPGAGG 349
ID+ +IGSCT G+ EDF+ AAK+ GRKV V +PA+ K +M + +
Sbjct: 291 IDQAFIGSCTNGRYEDFVEAAKILK--GRKVAPGVRCIAIPASLKQYMRLLKEGI----- 343
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
I EAGC A +CG CLGG L +V +S++NRNF GRMGH E ++Y
Sbjct: 344 ---IDILTEAGCFV-AHSTCGPCLGGHLGV---LGPGEVAISSSNRNFKGRMGHPESKVY 396
Query: 168 LASPYTAAASALTGRVADPREFL 100
LASP T AASA+ G++ADPR++L
Sbjct: 397 LASPATVAASAVEGKIADPRKYL 419
[94][TOP]
>UniRef100_A5IJM1 3-isopropylmalate dehydratase, large subunit n=2 Tax=Thermotogaceae
RepID=A5IJM1_THEP1
Length = 417
Score = 107 bits (267), Expect = 5e-22
Identities = 59/141 (41%), Positives = 81/141 (57%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KID+ IGSCT G+ ED AA++ V ++P +QKV+
Sbjct: 288 IKIDQAVIGSCTNGRIEDLRLAAQILKGRTVSPDVRCIIIPGSQKVYKQALK-------- 339
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ IF +AGC ++P+CG CLGG A E +V +STTNRNF GRMGH +++
Sbjct: 340 EGLIDIFIDAGCAV-STPTCGPCLGGHMGVLA---EGEVAISTTNRNFVGRMGHPNSKVF 395
Query: 168 LASPYTAAASALTGRVADPRE 106
LASP AAASA+ G +ADPR+
Sbjct: 396 LASPAVAAASAIKGYIADPRK 416
[95][TOP]
>UniRef100_A7H0L8 3-isopropylmalate dehydratase large subunit n=1 Tax=Campylobacter
curvus 525.92 RepID=LEUC_CAMC5
Length = 421
Score = 107 bits (267), Expect = 5e-22
Identities = 65/144 (45%), Positives = 86/144 (59%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLV--PATQKVWMDVYALPVPG 358
D+ ID+ +IGSCT G+ D AA++ GRKV T L+ PATQK+ +
Sbjct: 291 DIAIDQAFIGSCTNGRLSDLRIAAEILK--GRKVSRKTRLIITPATQKIAL--------A 340
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
A + IF EAG ++P+CGACLGG L + CVSTTNRNF GRMG +
Sbjct: 341 AQKEGLMDIFVEAGA-VVSNPTCGACLGGYMGI---LGAGERCVSTTNRNFVGRMGDRTS 396
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
++YLA+ AAASA+ G++ADPRE
Sbjct: 397 EVYLANSAVAAASAIAGKIADPRE 420
[96][TOP]
>UniRef100_Q9WZ24 3-isopropylmalate dehydratase large subunit 2 n=2 Tax=Thermotoga
RepID=LEUC2_THEMA
Length = 417
Score = 107 bits (267), Expect = 5e-22
Identities = 59/141 (41%), Positives = 81/141 (57%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KID+ IGSCT G+ ED AA++ V ++P +QKV+
Sbjct: 288 IKIDQAVIGSCTNGRIEDLRLAAQILKGRTVSPDVRCIIIPGSQKVYKQALK-------- 339
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ IF +AGC ++P+CG CLGG A E +V +STTNRNF GRMGH +++
Sbjct: 340 EGLIDIFIDAGCAV-STPTCGPCLGGHMGVLA---EGEVAISTTNRNFVGRMGHPNSKVF 395
Query: 168 LASPYTAAASALTGRVADPRE 106
LASP AAASA+ G +ADPR+
Sbjct: 396 LASPAVAAASAIKGYIADPRK 416
[97][TOP]
>UniRef100_C7I822 3-isopropylmalate dehydratase, large subunit n=1 Tax=Thermotoga
naphthophila RKU-10 RepID=C7I822_9THEM
Length = 417
Score = 107 bits (266), Expect = 7e-22
Identities = 58/141 (41%), Positives = 81/141 (57%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KID+ IGSCT G+ ED AA++ V ++P +QKV+
Sbjct: 288 IKIDQAVIGSCTNGRIEDLRLAAQILKGRTVSPDVRCIIIPGSQKVYKQALK-------- 339
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ +F +AGC ++P+CG CLGG A E +V +STTNRNF GRMGH +++
Sbjct: 340 EGLIDVFIDAGCAV-STPTCGPCLGGHMGVLA---EGEVAISTTNRNFVGRMGHPNSKVF 395
Query: 168 LASPYTAAASALTGRVADPRE 106
LASP AAASA+ G +ADPR+
Sbjct: 396 LASPAVAAASAIKGYIADPRK 416
[98][TOP]
>UniRef100_C4G1B4 Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC
49176 RepID=C4G1B4_ABIDE
Length = 421
Score = 107 bits (266), Expect = 7e-22
Identities = 62/144 (43%), Positives = 86/144 (59%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
D+KID+V IGSCT G+ D AA++ G+KV + ++PATQ+V++
Sbjct: 289 DIKIDQVVIGSCTNGRISDIRVAAEVMK--GKKVAPGIRVIVIPATQEVYLTSLK----- 341
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
+ F +AGC ++P+CG CLGG A + VSTTNRNF GRMGH E
Sbjct: 342 ---EGLITTFVQAGCIV-STPTCGPCLGGHMGVLAA---GERAVSTTNRNFVGRMGHTES 394
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
++YLASP AAASA+TG+++ P E
Sbjct: 395 EVYLASPAVAAASAITGKISSPEE 418
[99][TOP]
>UniRef100_C0WAT0 3-isopropylmalate dehydratase n=1 Tax=Acidaminococcus sp. D21
RepID=C0WAT0_9FIRM
Length = 418
Score = 107 bits (266), Expect = 7e-22
Identities = 60/142 (42%), Positives = 82/142 (57%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
D+ ID+V IGSCT G+ ED AAK+ V ++P +Q+V+ + A
Sbjct: 287 DIPIDQVVIGSCTNGRLEDLAIAAKILEGRTVHPDVRCIVIPGSQEVYKE--------AM 338
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
K F +AGC ++P+CG CLGG A + CVSTTNRNF GRMGH + ++
Sbjct: 339 KKGYIDTFIDAGC-VVSTPTCGPCLGGYMGILAA---GERCVSTTNRNFRGRMGHVDSEV 394
Query: 171 YLASPYTAAASALTGRVADPRE 106
YLA P AAASA+ G++A P+E
Sbjct: 395 YLAGPQVAAASAILGKIAAPKE 416
[100][TOP]
>UniRef100_C0D3T2 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
DSM 15981 RepID=C0D3T2_9CLOT
Length = 446
Score = 107 bits (266), Expect = 7e-22
Identities = 64/144 (44%), Positives = 88/144 (61%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKV--KVPTFLVPATQKVWMDVYALPVPG 358
DVKID+ IGSCT G+ +D AA++ GRKV V ++PATQ +++
Sbjct: 315 DVKIDQSVIGSCTNGRIDDMRVAAEILK--GRKVAKNVRCIVIPATQAIYLQ-------- 364
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
A + +IF EAG ++P+CG CLGG A + C+STTNRNF GRMGH +
Sbjct: 365 AMREGLLEIFVEAGAIV-STPTCGPCLGGYMGILAA---GERCISTTNRNFVGRMGHVDS 420
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
++YLASP AAASA+TG+++ P E
Sbjct: 421 EVYLASPAVAAASAVTGKISCPCE 444
[101][TOP]
>UniRef100_Q8PZT3 3-isopropylmalate dehydratase large subunit 1 n=1
Tax=Methanosarcina mazei RepID=LEUC1_METMA
Length = 391
Score = 107 bits (266), Expect = 7e-22
Identities = 65/139 (46%), Positives = 84/139 (60%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKT 343
+D+V+IG+CT G+ ED AA + G+KV V T ++PA++ + A
Sbjct: 267 VDQVFIGTCTNGRLEDLEVAASVLK--GKKVTVRTIIIPASRSTLL--------AAIKNG 316
Query: 342 CAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYLA 163
+I +AG T A+P CG CLG L E +VCVST NRNF GRMG K+G IYLA
Sbjct: 317 TMEILLKAGV-TLATPGCGPCLGAHQGV---LGEGEVCVSTANRNFKGRMG-KDGFIYLA 371
Query: 162 SPYTAAASALTGRVADPRE 106
SP TAAASALTG + DPR+
Sbjct: 372 SPATAAASALTGEITDPRK 390
[102][TOP]
>UniRef100_B5CQV8 Putative uncharacterized protein n=1 Tax=Ruminococcus lactaris ATCC
29176 RepID=B5CQV8_9FIRM
Length = 424
Score = 106 bits (265), Expect = 9e-22
Identities = 61/141 (43%), Positives = 80/141 (56%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KID+V IGSCT G+ ED AA + V ++PATQK++ +
Sbjct: 292 IKIDQVVIGSCTNGRMEDLRKAAAILKGHTVHPDVRVMVIPATQKIYKECIK-------- 343
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ IF +AGC +PSCG C+GG A + CVSTTNRNF GRMGH + IY
Sbjct: 344 EGLLDIFVDAGCAVN-TPSCGPCMGGHMGVMAA---GEKCVSTTNRNFVGRMGHVDSLIY 399
Query: 168 LASPYTAAASALTGRVADPRE 106
LASP AAASA+ G +A+P +
Sbjct: 400 LASPEVAAASAIAGCIANPEK 420
[103][TOP]
>UniRef100_A5KNQ3 Putative uncharacterized protein n=1 Tax=Ruminococcus torques ATCC
27756 RepID=A5KNQ3_9FIRM
Length = 451
Score = 106 bits (265), Expect = 9e-22
Identities = 63/141 (44%), Positives = 79/141 (56%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
VKID+V IGSCT G+ ED AA + V +VPATQK++
Sbjct: 299 VKIDQVVIGSCTNGRMEDMRKAAAILKGHTVHPDVRVMVVPATQKIYKQCIK-------- 350
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ IF +AGC +PSCG C+GG A + CVSTTNRNF GRMGH + IY
Sbjct: 351 EGLLDIFVDAGCAVN-TPSCGPCMGGHMGVMAA---GEKCVSTTNRNFVGRMGHVDSLIY 406
Query: 168 LASPYTAAASALTGRVADPRE 106
LASP AAASA+ G +A+P +
Sbjct: 407 LASPEVAAASAIKGYIANPEK 427
[104][TOP]
>UniRef100_Q12TV2 Homoaconitase large subunit n=1 Tax=Methanococcoides burtonii DSM
6242 RepID=Q12TV2_METBU
Length = 413
Score = 106 bits (265), Expect = 9e-22
Identities = 62/139 (44%), Positives = 85/139 (61%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
K+D+V+IG+CT G+ ED AA++ G +V V T ++PA++ + ++ A
Sbjct: 288 KVDQVFIGTCTNGRLEDLEVAAEILK--GEQVAVRTIVIPASRSIMLE--------AVRN 337
Query: 345 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
A+ +AG T SP CG CLGG + E +VC+ST NRNF GRMG K G IYL
Sbjct: 338 GTAETLLDAGV-TLGSPGCGPCLGGHMGV---IGEGEVCISTANRNFRGRMG-KGGFIYL 392
Query: 165 ASPYTAAASALTGRVADPR 109
+SP TAAASA+TG + DPR
Sbjct: 393 SSPATAAASAITGEITDPR 411
[105][TOP]
>UniRef100_B5YEF5 3-isopropylmalate dehydratase, large subunit n=1 Tax=Dictyoglomus
thermophilum H-6-12 RepID=B5YEF5_DICT6
Length = 424
Score = 106 bits (264), Expect = 1e-21
Identities = 63/143 (44%), Positives = 81/143 (56%), Gaps = 1/143 (0%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
D+ ID+VYIGSCT G+ ED AAK+ V + PAT ++M
Sbjct: 290 DIYIDQVYIGSCTNGRIEDLRIAAKILKGHKVHKDVRLIITPATPNIYMQALK------- 342
Query: 351 GKTCAQIFEEAGCD-TPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 175
+ +IF EAG TP PSCG CLGG A E + V+TTNRNF GRMGH + +
Sbjct: 343 -EGLIEIFLEAGASITP--PSCGPCLGGHLGVLA---EGEKAVATTNRNFVGRMGHPKSE 396
Query: 174 IYLASPYTAAASALTGRVADPRE 106
+YL++P AAASA+ GR+A P E
Sbjct: 397 VYLSNPAVAAASAILGRIAAPWE 419
[106][TOP]
>UniRef100_C9LTJ0 3-isopropylmalate dehydratase, large subunit n=1 Tax=Selenomonas
sputigena ATCC 35185 RepID=C9LTJ0_9FIRM
Length = 420
Score = 106 bits (264), Expect = 1e-21
Identities = 60/141 (42%), Positives = 80/141 (56%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KID+V IGSCT G+ ED +A L V ++P +Q V+ + L
Sbjct: 290 IKIDQVVIGSCTNGRLEDLEISAGLLKGHEVHPDVRCIVIPGSQAVYQEAMHLGY----- 344
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+F +AGC A+P+CG CLGG L + CVSTTNRNF GRMGH + ++Y
Sbjct: 345 ---IDVFIDAGCAV-AAPTCGPCLGGYMGI---LTAGERCVSTTNRNFRGRMGHVDSEVY 397
Query: 168 LASPYTAAASALTGRVADPRE 106
LA P+ AAASA+ GR+A P E
Sbjct: 398 LAGPHVAAASAILGRIAAPEE 418
[107][TOP]
>UniRef100_C0BZF9 Putative uncharacterized protein n=1 Tax=Clostridium hylemonae DSM
15053 RepID=C0BZF9_9CLOT
Length = 431
Score = 106 bits (264), Expect = 1e-21
Identities = 61/141 (43%), Positives = 80/141 (56%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
V+ID+V IGSCT G+ ED AA + V ++PATQK++ +
Sbjct: 299 VRIDQVVIGSCTNGRMEDMRRAAAVLKGHKVHPDVRAMIIPATQKIYKQCIS-------- 350
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ IF +AGC +PSCG C+GG A + CVSTTNRNF GRMGH + IY
Sbjct: 351 EGLVDIFIDAGCAFN-TPSCGPCMGGHMGVLAA---GEKCVSTTNRNFVGRMGHVDSLIY 406
Query: 168 LASPYTAAASALTGRVADPRE 106
LASP AAASA+ G +A+P +
Sbjct: 407 LASPEVAAASAIAGHIANPEK 427
[108][TOP]
>UniRef100_B1C4Q4 Putative uncharacterized protein n=1 Tax=Clostridium spiroforme DSM
1552 RepID=B1C4Q4_9FIRM
Length = 424
Score = 106 bits (264), Expect = 1e-21
Identities = 65/143 (45%), Positives = 84/143 (58%), Gaps = 2/143 (1%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKV--KVPTFLVPATQKVWMDVYALPVPGA 355
+ ID+V IGSCT G+ D AA + G+KV V +VPATQK+++
Sbjct: 292 IYIDQVVIGSCTNGRISDLRKAAAILK--GKKVARNVRVMVVPATQKIFLQCIV------ 343
Query: 354 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 175
+ A+IF EAGC +PSCG C+GG A+ + CVSTTNRNF GRMG E
Sbjct: 344 --EGLAEIFVEAGCAFN-TPSCGPCMGGHMGVMAK---GEKCVSTTNRNFVGRMGDTEAL 397
Query: 174 IYLASPYTAAASALTGRVADPRE 106
IYLASP AAASA+ G +A+P +
Sbjct: 398 IYLASPEVAAASAIAGYIANPEK 420
[109][TOP]
>UniRef100_B0NJ74 Putative uncharacterized protein n=1 Tax=Clostridium scindens ATCC
35704 RepID=B0NJ74_EUBSP
Length = 424
Score = 106 bits (264), Expect = 1e-21
Identities = 65/143 (45%), Positives = 83/143 (58%), Gaps = 2/143 (1%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPGA 355
+KID+V IGSCT G+ ED AA + GRKV V ++PATQK++
Sbjct: 292 IKIDQVVIGSCTNGRMEDMRRAAAVLK--GRKVHPDVRVMVIPATQKIYKQCIK------ 343
Query: 354 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 175
+ IF +AGC +PSCG C+GG A + CVSTTNRNF GRMGH +
Sbjct: 344 --EGLVDIFIDAGCAFN-TPSCGPCMGGHMGVLAA---GEKCVSTTNRNFVGRMGHVDSL 397
Query: 174 IYLASPYTAAASALTGRVADPRE 106
IYLASP AAASA+ G +A+P +
Sbjct: 398 IYLASPEVAAASAIAGCIANPEK 420
[110][TOP]
>UniRef100_A0RMG7 3-isopropylmalate dehydratase large subunit n=1 Tax=Campylobacter
fetus subsp. fetus 82-40 RepID=LEUC_CAMFF
Length = 421
Score = 106 bits (264), Expect = 1e-21
Identities = 64/143 (44%), Positives = 87/143 (60%), Gaps = 2/143 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLV--PATQKVWMDVYALPVPG 358
D+KID+V+IGSCT G+ D AA++ G++V T L+ PATQK+ +
Sbjct: 291 DLKIDQVFIGSCTNGRLSDLRIAARILK--GKRVAKHTRLIITPATQKIAL--------A 340
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
A + IF EAG ++P+CGACLGG L + CVSTTNRNF GRMG +
Sbjct: 341 AQKEGLMDIFVEAGA-VVSNPTCGACLGGYMGI---LGAGERCVSTTNRNFVGRMGDRTS 396
Query: 177 QIYLASPYTAAASALTGRVADPR 109
++YLA+ AAASA+ G++ADPR
Sbjct: 397 EVYLANSAVAAASAIAGKIADPR 419
[111][TOP]
>UniRef100_C0CTF8 Putative uncharacterized protein (Fragment) n=1 Tax=Clostridium
asparagiforme DSM 15981 RepID=C0CTF8_9CLOT
Length = 134
Score = 105 bits (263), Expect = 2e-21
Identities = 65/143 (45%), Positives = 85/143 (59%), Gaps = 2/143 (1%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLV--PATQKVWMDVYALPVPGA 355
V+I + YIGSCTGG+ D AA+L GRK+ L+ PA+++++ +
Sbjct: 5 VRIHQAYIGSCTGGRYHDLKMAAELLR--GRKIAPGLRLLVSPASREIYNQCLREGI--- 59
Query: 354 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 175
++ EAG AS SCGACLG + T A + +VC+STTNRNF GRMG K
Sbjct: 60 -----LEVLAEAGATVLAS-SCGACLGIHSGTLA---DGEVCISTTNRNFIGRMGSKTSS 110
Query: 174 IYLASPYTAAASALTGRVADPRE 106
+YLASP T AASALTG + DPRE
Sbjct: 111 VYLASPVTVAASALTGHITDPRE 133
[112][TOP]
>UniRef100_A4J182 3-isopropylmalate dehydratase, large subunit n=1
Tax=Desulfotomaculum reducens MI-1 RepID=A4J182_DESRM
Length = 418
Score = 105 bits (262), Expect = 2e-21
Identities = 58/143 (40%), Positives = 85/143 (59%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
V ID+ IGSCT G+ ED AA++ +V ++P TQ+++ A
Sbjct: 288 VDIDQAVIGSCTNGRMEDLRLAAEILKGKKVHQQVRLIVIPGTQEIYRQ--------AMR 339
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ +IF +AG ++P+CG CLGG A+ + C++TTNRNF GRMGH E ++Y
Sbjct: 340 EGLFEIFLDAGA-VVSTPTCGPCLGGHMGILAK---GERCIATTNRNFVGRMGHAESEVY 395
Query: 168 LASPYTAAASALTGRVADPREFL 100
LA+P AAASA+TGR++ P+E L
Sbjct: 396 LANPAVAAASAITGRISHPQEVL 418
[113][TOP]
>UniRef100_C8PKG7 3-isopropylmalate dehydratase large subunit n=1 Tax=Campylobacter
gracilis RM3268 RepID=C8PKG7_9PROT
Length = 421
Score = 105 bits (262), Expect = 2e-21
Identities = 64/144 (44%), Positives = 87/144 (60%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLV--PATQKVWMDVYALPVPG 358
D+ +D+V+IGSCT G+ D AA++ GRKV T L+ PATQK+ +
Sbjct: 291 DIAVDQVFIGSCTNGRLSDLRIAAQILK--GRKVARKTRLIITPATQKIAL--------A 340
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
A + IF EAG ++P+CGACLGG L + CVSTTNRNF GRMG +
Sbjct: 341 AQKEGLWDIFVEAGA-VVSNPTCGACLGGYMGI---LGVGERCVSTTNRNFVGRMGDRTS 396
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
++YLA+ AAASA+ G++ADPR+
Sbjct: 397 EVYLANSAVAAASAVAGKIADPRD 420
[114][TOP]
>UniRef100_C3RJS7 Putative uncharacterized protein n=1 Tax=Mollicutes bacterium D7
RepID=C3RJS7_9MOLU
Length = 422
Score = 105 bits (262), Expect = 2e-21
Identities = 62/141 (43%), Positives = 80/141 (56%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+ ID+V IGSCT G+ D AA + V +VPATQK+++
Sbjct: 290 IMIDQVVIGSCTNGRLSDLRKAAAILKGKQVAKNVRVMVVPATQKIFVQCIH-------- 341
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ A+IF EAGC +PSCG C+GG A+ + CVSTTNRNF GRMG E IY
Sbjct: 342 EGLAEIFVEAGCAFN-TPSCGPCMGGHMGVMAK---GEKCVSTTNRNFVGRMGDTEALIY 397
Query: 168 LASPYTAAASALTGRVADPRE 106
LASP AAASA+ G +A+P +
Sbjct: 398 LASPEVAAASAIAGYIANPEK 418
[115][TOP]
>UniRef100_B9D2G7 3-isopropylmalate dehydratase, large subunit n=1 Tax=Campylobacter
rectus RM3267 RepID=B9D2G7_WOLRE
Length = 424
Score = 105 bits (262), Expect = 2e-21
Identities = 64/144 (44%), Positives = 86/144 (59%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLV--PATQKVWMDVYALPVPG 358
D+ ID+ +IGSCT G+ D AA++ GRKV T L+ PATQK+ +
Sbjct: 294 DIAIDQAFIGSCTNGRLSDLRIAAEILK--GRKVARKTRLIITPATQKIALQ-------- 343
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
A + IF EAG ++P+CGACLGG L + CVSTTNRNF GRMG +
Sbjct: 344 AQKEGLMDIFAEAGA-VVSNPTCGACLGGYMGI---LGVGERCVSTTNRNFVGRMGDRTS 399
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
++YLA+ AAASA+ G++ADPR+
Sbjct: 400 EVYLANSAVAAASAVVGKIADPRD 423
[116][TOP]
>UniRef100_B0N943 Putative uncharacterized protein n=1 Tax=Clostridium ramosum DSM
1402 RepID=B0N943_9FIRM
Length = 424
Score = 105 bits (262), Expect = 2e-21
Identities = 62/141 (43%), Positives = 80/141 (56%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+ ID+V IGSCT G+ D AA + V +VPATQK+++
Sbjct: 292 IMIDQVVIGSCTNGRLSDLRKAAAILKGKQVAKNVRVMVVPATQKIFVQCIH-------- 343
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ A+IF EAGC +PSCG C+GG A+ + CVSTTNRNF GRMG E IY
Sbjct: 344 EGLAEIFVEAGCAFN-TPSCGPCMGGHMGVMAK---GEKCVSTTNRNFVGRMGDTEALIY 399
Query: 168 LASPYTAAASALTGRVADPRE 106
LASP AAASA+ G +A+P +
Sbjct: 400 LASPEVAAASAIAGYIANPEK 420
[117][TOP]
>UniRef100_B0G7V2 Putative uncharacterized protein n=1 Tax=Dorea formicigenerans ATCC
27755 RepID=B0G7V2_9FIRM
Length = 425
Score = 105 bits (262), Expect = 2e-21
Identities = 61/141 (43%), Positives = 79/141 (56%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KID+V IGSCT G+ ED AA + V ++PATQK++
Sbjct: 292 IKIDQVVIGSCTNGRMEDMRKAAAILKGHKVHEDVRVMVIPATQKIYKQCIH-------- 343
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ IF +AGC +PSCG C+GG A + CVSTTNRNF GRMGH + IY
Sbjct: 344 EGLMDIFVDAGCAVN-TPSCGPCMGGHMGVMAA---GEKCVSTTNRNFVGRMGHVDSLIY 399
Query: 168 LASPYTAAASALTGRVADPRE 106
LASP AAASA+ G +A+P +
Sbjct: 400 LASPEVAAASAIAGCIANPEK 420
[118][TOP]
>UniRef100_A7B6Z9 Putative uncharacterized protein n=1 Tax=Ruminococcus gnavus ATCC
29149 RepID=A7B6Z9_RUMGN
Length = 425
Score = 105 bits (262), Expect = 2e-21
Identities = 61/139 (43%), Positives = 78/139 (56%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KID+V IGSCT G+ ED AA + V ++PATQK++
Sbjct: 292 IKIDQVVIGSCTNGRMEDMRKAAAILKGHTVHPDVRVMVIPATQKIYKQCIK-------- 343
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ IF +AGC +PSCG C+GG A + CVSTTNRNF GRMGH + IY
Sbjct: 344 EGLLDIFVDAGCAVN-TPSCGPCMGGHMGVMAA---GERCVSTTNRNFVGRMGHVDSLIY 399
Query: 168 LASPYTAAASALTGRVADP 112
LASP AAASA+ G +A+P
Sbjct: 400 LASPEVAAASAIAGYIANP 418
[119][TOP]
>UniRef100_B1L3C3 Homoaconitate hydratase family protein n=1 Tax=Candidatus
Korarchaeum cryptofilum OPF8 RepID=B1L3C3_KORCO
Length = 384
Score = 105 bits (262), Expect = 2e-21
Identities = 60/143 (41%), Positives = 86/143 (60%), Gaps = 2/143 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
D +ID+ +IGSCTGG+ +D AA++ GR+VK V ++PA+++++++ +
Sbjct: 253 DAEIDQAFIGSCTGGRLKDLEVAARILR--GRRVKEGVRLIVIPASRRIYLEALRRGI-- 308
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
I E+G T PSCG CLG A E +V +ST+NRNF GRMGH E
Sbjct: 309 ------IDILIESGA-TIGPPSCGPCLGAHLGVLA---EGEVAISTSNRNFRGRMGHPES 358
Query: 177 QIYLASPYTAAASALTGRVADPR 109
++YLAS T AASA+ GR+ DPR
Sbjct: 359 RVYLASAATVAASAVEGRIVDPR 381
[120][TOP]
>UniRef100_Q74BX5 3-isopropylmalate dehydratase large subunit n=1 Tax=Geobacter
sulfurreducens RepID=LEUC_GEOSL
Length = 427
Score = 105 bits (262), Expect = 2e-21
Identities = 64/142 (45%), Positives = 85/142 (59%), Gaps = 1/142 (0%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKT 343
+D+VY+GSCT G+ ED AA++ V L PAT K++ D A +
Sbjct: 300 VDQVYLGSCTNGRLEDLRIAARILKGKKIAPTVRGILSPATPKIYQD--------AMREG 351
Query: 342 CAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
IF EAG C T +P+CGACLG A E +VC STTNRNF GRMG K G ++L
Sbjct: 352 LIDIFMEAGFCVT--NPTCGACLGMSNGVLA---EGEVCASTTNRNFMGRMG-KGGMVHL 405
Query: 165 ASPYTAAASALTGRVADPREFL 100
SP T+AA+A+ G++ADPR++L
Sbjct: 406 MSPATSAATAIEGKIADPRKYL 427
[121][TOP]
>UniRef100_O28084 3-isopropylmalate dehydratase large subunit 2 n=1 Tax=Archaeoglobus
fulgidus RepID=LEUC2_ARCFU
Length = 416
Score = 105 bits (262), Expect = 2e-21
Identities = 63/144 (43%), Positives = 89/144 (61%), Gaps = 2/144 (1%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPGAG 352
++++VYIG+CT G+ D AA++ GRKVK V +VPA+++V++ A
Sbjct: 287 EVNQVYIGTCTNGRLSDLEVAARILK--GRKVKEGVRLIVVPASRRVYLQ--------AL 336
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
K ++F EAG +P CG C+G A + +VC+ST NRNF GRMG+ +I
Sbjct: 337 DKGLIRVFVEAG-GMVLNPGCGPCVGIHQGILA---DGEVCISTQNRNFKGRMGNPNAEI 392
Query: 171 YLASPYTAAASALTGRVADPREFL 100
+LASP TAAASA+ G +ADPREFL
Sbjct: 393 FLASPATAAASAVKGYIADPREFL 416
[122][TOP]
>UniRef100_Q6ALT9 Probable 3-isopropylmalate dehydratase, large subunit n=1
Tax=Desulfotalea psychrophila RepID=Q6ALT9_DESPS
Length = 427
Score = 105 bits (261), Expect = 3e-21
Identities = 61/142 (42%), Positives = 84/142 (59%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
K+D++YIGSCT G+ ED AAA + V + PAT K +Y++ + +
Sbjct: 299 KVDQIYIGSCTNGRIEDLRAAASILKGRTLATGVRGIVTPATPK----IYSMALE----E 350
Query: 345 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
+IF +AG +P+CGACLG + A E +VC STTNRNF GRMG K G ++L
Sbjct: 351 GIIKIFMDAGF-CVLNPTCGACLGMSSGVLA---EGEVCASTTNRNFNGRMG-KGGMVHL 405
Query: 165 ASPYTAAASALTGRVADPREFL 100
SPY+A A+TG + DPR+FL
Sbjct: 406 MSPYSATVGAVTGTITDPRQFL 427
[123][TOP]
>UniRef100_C0R088 3-isopropylmalate dehydratase large subunit n=1 Tax=Brachyspira
hyodysenteriae WA1 RepID=C0R088_BRAHW
Length = 415
Score = 105 bits (261), Expect = 3e-21
Identities = 62/143 (43%), Positives = 85/143 (59%), Gaps = 2/143 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
++K+D+V IGSCT G+ D AA + G+KV V ++PATQKV+ + L
Sbjct: 287 NIKVDQVVIGSCTNGRLSDMATAANILK--GKKVAKGVRCIVIPATQKVYKECIKLGY-- 342
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
IF +AGC ++P+CG CLGG A +V V+TTNRNF GRMG K
Sbjct: 343 ------MDIFIDAGCAV-STPTCGPCLGGYMGILAH---DEVAVTTTNRNFVGRMGDKTS 392
Query: 177 QIYLASPYTAAASALTGRVADPR 109
++YLASP TAA SA+TG + +P+
Sbjct: 393 KVYLASPATAAYSAITGYITEPK 415
[124][TOP]
>UniRef100_C6RH21 3-isopropylmalate dehydratase, large subunit n=1 Tax=Campylobacter
showae RM3277 RepID=C6RH21_9PROT
Length = 424
Score = 105 bits (261), Expect = 3e-21
Identities = 64/144 (44%), Positives = 86/144 (59%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLV--PATQKVWMDVYALPVPG 358
D+ ID+ +IGSCT G+ D AA++ GRKV T L+ PATQK+ +
Sbjct: 294 DIAIDQAFIGSCTNGRLSDLRIAAEILK--GRKVARKTRLIITPATQKIALQ-------- 343
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
A + IF EAG ++P+CGACLGG L + CVSTTNRNF GRMG +
Sbjct: 344 AQKEGLMDIFAEAGA-VVSNPTCGACLGGYMGI---LGVGERCVSTTNRNFVGRMGDRTS 399
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
++YLA+ AAASA+ G++ADPR+
Sbjct: 400 EVYLANSAVAAASAVMGKIADPRD 423
[125][TOP]
>UniRef100_C2A003 3-isopropylmalate dehydratase, large subunit n=1
Tax=Sulfurospirillum deleyianum DSM 6946
RepID=C2A003_SULDE
Length = 421
Score = 105 bits (261), Expect = 3e-21
Identities = 65/143 (45%), Positives = 87/143 (60%), Gaps = 2/143 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLV--PATQKVWMDVYALPVPG 358
D+ ID+V+IGSCT G+ ED AA + GRKV T L+ PATQK+ +
Sbjct: 291 DLAIDQVFIGSCTNGRLEDLRIAASILK--GRKVARKTRLIITPATQKISLQ-------- 340
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
A + +IF EAG ++P+CGACLGG L + + CV+TTNRNF GRMG +
Sbjct: 341 AQKEGLVEIFIEAGA-VFSNPTCGACLGGYMGI---LGKNERCVATTNRNFVGRMGDRTS 396
Query: 177 QIYLASPYTAAASALTGRVADPR 109
+IYLA+ AAASA+ G++ DPR
Sbjct: 397 EIYLANSAVAAASAVMGKITDPR 419
[126][TOP]
>UniRef100_A6Q5L6 3-isopropylmalate dehydratase large subunit n=1 Tax=Nitratiruptor
sp. SB155-2 RepID=LEUC_NITSB
Length = 421
Score = 105 bits (261), Expect = 3e-21
Identities = 64/144 (44%), Positives = 88/144 (61%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLV--PATQKVWMDVYALPVPG 358
D+K+D+V+IGSCT G+ D AA++ GRKV T ++ PATQK+ +
Sbjct: 291 DLKVDQVFIGSCTNGRLSDIAIAAEILK--GRKVARHTRMIVTPATQKILKE-------- 340
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
A + I +AG ++P+CGACLGG A + + CVSTTNRNF GRMG +
Sbjct: 341 AEKRGYIDILIDAGA-VVSNPTCGACLGGYMGILA---DNERCVSTTNRNFVGRMGARTS 396
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
+IYLA+ AAASA+ G++ADPRE
Sbjct: 397 EIYLANSAVAAASAVAGKIADPRE 420
[127][TOP]
>UniRef100_A5G7U4 3-isopropylmalate dehydratase large subunit n=1 Tax=Geobacter
uraniireducens Rf4 RepID=LEUC_GEOUR
Length = 427
Score = 105 bits (261), Expect = 3e-21
Identities = 65/142 (45%), Positives = 85/142 (59%), Gaps = 1/142 (0%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKT 343
+D+VY+GSCT G+ ED AA++ V L PAT KV+ D A +
Sbjct: 300 VDQVYLGSCTNGRLEDLRVAAEILKGKKIAPTVRAILSPATPKVYSD--------ALHEG 351
Query: 342 CAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
IF EAG C T +P+CGACLG A E +VC STTNRNF GRMG K G ++L
Sbjct: 352 LIDIFMEAGFCVT--NPTCGACLGMSNGVLA---EGEVCASTTNRNFMGRMG-KGGMVHL 405
Query: 165 ASPYTAAASALTGRVADPREFL 100
SP T+AA+A+ G++ADPR++L
Sbjct: 406 MSPATSAATAIEGKMADPRKYL 427
[128][TOP]
>UniRef100_Q39W70 3-isopropylmalate dehydratase large subunit n=1 Tax=Geobacter
metallireducens GS-15 RepID=LEUC_GEOMG
Length = 427
Score = 105 bits (261), Expect = 3e-21
Identities = 64/142 (45%), Positives = 84/142 (59%), Gaps = 1/142 (0%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKT 343
+D+VY+GSCT G+ ED AA++ V L PAT K++ D A +
Sbjct: 300 VDQVYLGSCTNGRLEDLRIAARILKGKKIAPSVRGILSPATPKIYKDAMA--------EG 351
Query: 342 CAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
IF EAG C T +P+CGACLG A E +VC STTNRNF GRMG K G ++L
Sbjct: 352 LIDIFMEAGFCVT--NPTCGACLGMSNGVLA---EGEVCASTTNRNFMGRMG-KGGMVHL 405
Query: 165 ASPYTAAASALTGRVADPREFL 100
SP T+AA+A+ G +ADPR++L
Sbjct: 406 MSPATSAATAIEGVIADPRKYL 427
[129][TOP]
>UniRef100_B8E2X0 3-isopropylmalate dehydratase, large subunit n=1 Tax=Dictyoglomus
turgidum DSM 6724 RepID=B8E2X0_DICTD
Length = 424
Score = 104 bits (260), Expect = 3e-21
Identities = 63/143 (44%), Positives = 80/143 (55%), Gaps = 1/143 (0%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
D+ ID+VYIGSCT G+ ED AAK+ V + PAT V+M
Sbjct: 290 DIYIDQVYIGSCTNGRIEDLRLAAKILKGHKVHKDVRLIVTPATPNVYMQALK------- 342
Query: 351 GKTCAQIFEEAGCD-TPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 175
+ +IF E G TP PSCG CLGG A E + V+TTNRNF GRMGH + +
Sbjct: 343 -EGLIEIFLEVGASITP--PSCGPCLGGHLGVLA---EGEKAVATTNRNFVGRMGHPKSE 396
Query: 174 IYLASPYTAAASALTGRVADPRE 106
+YL++P AAASA+ GR+A P E
Sbjct: 397 VYLSNPAVAAASAILGRIAAPWE 419
[130][TOP]
>UniRef100_C4ETQ1 3-isopropylmalate dehydratase, large subunit n=1
Tax=Thermanaerovibrio acidaminovorans DSM 6589
RepID=C4ETQ1_9BACT
Length = 420
Score = 104 bits (260), Expect = 3e-21
Identities = 60/142 (42%), Positives = 83/142 (58%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
+I + +IGSCT G+ ED AA + GR+V V T ++PA+ +V+ A +
Sbjct: 293 QIHQAFIGSCTNGRIEDLREAATILK--GRQVAVRTIVIPASWRVYRQ--------AMEE 342
Query: 345 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
+ F +AGC ++P CG C+G A + C+ST NRNF GRMG+K+ IYL
Sbjct: 343 GLLETFLDAGC-VISNPGCGPCMGNHQGILA---PGETCISTANRNFKGRMGNKDSFIYL 398
Query: 165 ASPYTAAASALTGRVADPREFL 100
ASP T AASA+ G +ADPRE L
Sbjct: 399 ASPLTVAASAVAGEIADPREVL 420
[131][TOP]
>UniRef100_B1QZX5 3-isopropylmalate dehydratase, large subunit n=2 Tax=Clostridium
butyricum RepID=B1QZX5_CLOBU
Length = 419
Score = 104 bits (260), Expect = 3e-21
Identities = 58/140 (41%), Positives = 79/140 (56%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKID+V IGSCT G+ D A + + ++P TQK+++ +
Sbjct: 289 DVKIDQVVIGSCTNGRISDLRVARDILKGKKVDKTIRCIVIPGTQKIYLQALEEGI---- 344
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ EAG ++P+CG CLGG A+ + CVSTTNRNF GRMGH E ++
Sbjct: 345 ----IKDLIEAGAIV-STPTCGPCLGGHMGILAK---DERCVSTTNRNFVGRMGHVESEV 396
Query: 171 YLASPYTAAASALTGRVADP 112
YLASP AAASA+TG++ DP
Sbjct: 397 YLASPAVAAASAITGKITDP 416
[132][TOP]
>UniRef100_A5ZAM9 Putative uncharacterized protein n=1 Tax=Eubacterium ventriosum
ATCC 27560 RepID=A5ZAM9_9FIRM
Length = 421
Score = 104 bits (260), Expect = 3e-21
Identities = 60/142 (42%), Positives = 81/142 (57%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DVKID+V IGSCT G+ ED AAK+ V + PATQ +++ +
Sbjct: 289 DVKIDQVVIGSCTNGRIEDMRTAAKILEGREVAKGVRCIVFPATQAIYLQCIEEGI---- 344
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
F +AGC ++P+CG CLGG A+ + V+TTNRNF GRMG E ++
Sbjct: 345 ----MTTFIKAGCAV-STPTCGPCLGGHMGILAK---GERAVATTNRNFVGRMGDPESEV 396
Query: 171 YLASPYTAAASALTGRVADPRE 106
YLASP AAASA+TG+++ P E
Sbjct: 397 YLASPAVAAASAITGKISGPEE 418
[133][TOP]
>UniRef100_A6Q6J8 3-isopropylmalate dehydratase large subunit n=1 Tax=Sulfurovum sp.
NBC37-1 RepID=LEUC_SULNB
Length = 426
Score = 104 bits (260), Expect = 3e-21
Identities = 64/144 (44%), Positives = 87/144 (60%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLV--PATQKVWMDVYALPVPG 358
D+KID+V IGSCT G+ ED AA++ G++V T ++ PATQK+ M
Sbjct: 296 DLKIDQVMIGSCTNGRIEDLRIAAEIMK--GKRVAKHTRMIVTPATQKILMQ-------- 345
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
A + I EAG ++P+CGACLGG L + + CV+TTNRNF GRMG +
Sbjct: 346 AQHEGLMDILIEAGA-VVSNPTCGACLGGYMGI---LGDGERCVATTNRNFVGRMGARTS 401
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
+IYLA+ AAASA+ G++ DPRE
Sbjct: 402 EIYLANSAVAAASAIAGKIVDPRE 425
[134][TOP]
>UniRef100_Q1IZK5 3-isopropylmalate dehydratase large subunit n=1 Tax=Deinococcus
geothermalis DSM 11300 RepID=Q1IZK5_DEIGD
Length = 431
Score = 104 bits (259), Expect = 4e-21
Identities = 62/144 (43%), Positives = 81/144 (56%), Gaps = 2/144 (1%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPGA 355
+ I Y+GSCT G+ D A++ GR+V V +VPATQ +W A
Sbjct: 291 IPITHAYVGSCTNGRIGDLRDVARILK--GRRVADGVQMIVVPATQAIWKQ--------A 340
Query: 354 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 175
+ +IF EAG + PSCGACLG + L VC+S++NRNF GRMG Q
Sbjct: 341 AQEGLLEIFVEAGASV-SYPSCGACLGMHSGV---LGPGDVCISSSNRNFVGRMGDPSAQ 396
Query: 174 IYLASPYTAAASALTGRVADPREF 103
IYLASP T AASA+ G ++DPRE+
Sbjct: 397 IYLASPATVAASAVAGYISDPREY 420
[135][TOP]
>UniRef100_A1ALN5 3-isopropylmalate dehydratase, large subunit n=1 Tax=Pelobacter
propionicus DSM 2379 RepID=A1ALN5_PELPD
Length = 427
Score = 104 bits (259), Expect = 4e-21
Identities = 65/143 (45%), Positives = 85/143 (59%), Gaps = 1/143 (0%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
K+D++Y+GSCT G+ ED AA + V L PAT KV+ + A +
Sbjct: 299 KVDQIYLGSCTNGRLEDLRIAAGILKGKKLAPHVRGILSPATPKVYQE--------ALKE 350
Query: 345 TCAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+IF EAG C T +P+CGACLG A E +VC +TTNRNF GRMG K G ++
Sbjct: 351 GLMEIFMEAGFCIT--NPTCGACLGMSNGVLA---EGEVCAATTNRNFMGRMG-KGGMVH 404
Query: 168 LASPYTAAASALTGRVADPREFL 100
L SP TAAASA+ G +ADPR++L
Sbjct: 405 LMSPATAAASAIEGVIADPRKYL 427
[136][TOP]
>UniRef100_A6LPX4 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
beijerinckii NCIMB 8052 RepID=LEUC_CLOB8
Length = 419
Score = 104 bits (259), Expect = 4e-21
Identities = 62/142 (43%), Positives = 82/142 (57%), Gaps = 2/142 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
DV ID+V IGSCT G+ D A + G+KVK + ++P TQK+++ +
Sbjct: 289 DVAIDQVVIGSCTNGRISDLRMARDILK--GKKVKKGIRCIVIPGTQKIYLQAIKEGI-- 344
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
EAG ++P+CG CLGG A+ + CVSTTNRNF GRMGH E
Sbjct: 345 ------VTDLVEAGAAF-STPTCGPCLGGHMGILAK---GERCVSTTNRNFVGRMGHVES 394
Query: 177 QIYLASPYTAAASALTGRVADP 112
++YLASP AAASALTG++ DP
Sbjct: 395 EVYLASPAVAAASALTGKITDP 416
[137][TOP]
>UniRef100_C1CVE2 Putative 3-isopropylmalate dehydratase, large subunit
(Isopropylmalate isomerase) (Alpha-IPM isomerase) n=1
Tax=Deinococcus deserti VCD115 RepID=C1CVE2_DEIDV
Length = 426
Score = 103 bits (258), Expect = 6e-21
Identities = 61/144 (42%), Positives = 81/144 (56%), Gaps = 2/144 (1%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPGA 355
+ + Y+GSCT G+ D A++ GRKV V +VPATQ +W A
Sbjct: 291 IAVTHAYVGSCTNGRIGDLREVARILK--GRKVADGVQMIVVPATQAIWKQ--------A 340
Query: 354 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 175
+ +IF +AG + PSCGACLG + L VC+S++NRNF GRMG Q
Sbjct: 341 AQEGLMEIFVDAGASV-SYPSCGACLGMHSGV---LGPDDVCISSSNRNFVGRMGDPTAQ 396
Query: 174 IYLASPYTAAASALTGRVADPREF 103
IYLASP T AASA+ G ++DPRE+
Sbjct: 397 IYLASPATVAASAVAGFISDPREY 420
[138][TOP]
>UniRef100_B9M5E2 Homoaconitate hydratase family protein n=1 Tax=Geobacter sp. FRC-32
RepID=B9M5E2_GEOSF
Length = 427
Score = 103 bits (258), Expect = 6e-21
Identities = 63/142 (44%), Positives = 84/142 (59%), Gaps = 1/142 (0%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKT 343
+D+VY+GSCT G+ ED AA + V L PAT K++ D A +
Sbjct: 300 VDQVYLGSCTNGRLEDLRIAAAILKGKKIASSVRAILSPATPKIYSD--------ALNEG 351
Query: 342 CAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
IF +AG C T +P+CGACLG A E +VC STTNRNF GRMG K G ++L
Sbjct: 352 LIAIFMDAGFCVT--NPTCGACLGMSNGVLA---EGEVCASTTNRNFMGRMG-KGGMVHL 405
Query: 165 ASPYTAAASALTGRVADPREFL 100
SP T+AA+A+ G++ADPR++L
Sbjct: 406 MSPATSAATAIEGKIADPRKYL 427
[139][TOP]
>UniRef100_Q9RTI6 3-isopropylmalate dehydratase large subunit 2 n=1 Tax=Deinococcus
radiodurans RepID=LEUC2_DEIRA
Length = 431
Score = 103 bits (258), Expect = 6e-21
Identities = 60/144 (41%), Positives = 81/144 (56%), Gaps = 2/144 (1%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPGA 355
+++ Y+GSCT G+ D A++ GRKV V +VPATQ +W A
Sbjct: 291 IRVTHAYVGSCTNGRITDLRDVARILK--GRKVAQDVQMIVVPATQAIWKQ--------A 340
Query: 354 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 175
+ +IF +AG + PSCGACLG + L +C+S++NRNF GRMG Q
Sbjct: 341 AQEGLLEIFVDAGASV-SYPSCGACLGMHSGV---LGPDDICISSSNRNFVGRMGDPSAQ 396
Query: 174 IYLASPYTAAASALTGRVADPREF 103
IYLASP T AASA+ G +ADPR +
Sbjct: 397 IYLASPATVAASAVEGFIADPRRY 420
[140][TOP]
>UniRef100_B6FST2 Putative uncharacterized protein n=1 Tax=Clostridium nexile DSM
1787 RepID=B6FST2_9CLOT
Length = 438
Score = 103 bits (257), Expect = 8e-21
Identities = 60/141 (42%), Positives = 79/141 (56%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KID+V IGSCT G+ ED AA + V ++PATQK+++
Sbjct: 306 IKIDQVVIGSCTNGRMEDMRRAAAVLKGHKVHPDVRVMVIPATQKIYLQCIE-------- 357
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ F E+GC +PSCG C+GG A + CVSTTNRNF GRMGH + IY
Sbjct: 358 EGLVTTFIESGCAFN-TPSCGPCMGGHMGVMAA---GEKCVSTTNRNFVGRMGHVDSLIY 413
Query: 168 LASPYTAAASALTGRVADPRE 106
LASP AAASA+ G +A+P +
Sbjct: 414 LASPEVAAASAIAGCIANPEK 434
[141][TOP]
>UniRef100_A8EQZ0 3-isopropylmalate dehydratase large subunit n=1 Tax=Arcobacter
butzleri RM4018 RepID=LEUC_ARCB4
Length = 426
Score = 103 bits (257), Expect = 8e-21
Identities = 61/143 (42%), Positives = 85/143 (59%), Gaps = 2/143 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
++K+D+V+IGSCT G+ DF AA++ AG+KV V L P TQK+ + L
Sbjct: 296 NIKVDQVFIGSCTNGRLSDFKIAAEIL--AGQKVARHVRLILTPGTQKILREATKLGY-- 351
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
+AG ++P+CGACLGG L + +VC+STTNRNF GRMG +
Sbjct: 352 ------IDTLVDAGA-VVSNPTCGACLGGYMGI---LGDNEVCISTTNRNFVGRMGSRSS 401
Query: 177 QIYLASPYTAAASALTGRVADPR 109
+IYLA+ AAASA++G + DPR
Sbjct: 402 KIYLANSAVAAASAISGYITDPR 424
[142][TOP]
>UniRef100_UPI00016C5FE1 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
difficile QCD-97b34 RepID=UPI00016C5FE1
Length = 425
Score = 103 bits (256), Expect = 1e-20
Identities = 61/146 (41%), Positives = 84/146 (57%), Gaps = 2/146 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
D+KID+V IGSCT G+ D A++ G+KV V + P TQKV+++
Sbjct: 294 DIKIDQVVIGSCTNGRISDLEVVAEIMK--GKKVADGVRVMIFPGTQKVYLEAIE----- 346
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
K F EAG ++P+CG CLGG A + +STTNRNF GRMGH +
Sbjct: 347 ---KGYITTFIEAGAAV-STPTCGPCLGGHMGILAA---GEKSISTTNRNFVGRMGHVDS 399
Query: 177 QIYLASPYTAAASALTGRVADPREFL 100
++YLASP AAASA+TG+++ P E +
Sbjct: 400 EVYLASPAVAAASAITGKISKPSEII 425
[143][TOP]
>UniRef100_UPI00006DC4EC hypothetical protein CdifQ_04001012 n=1 Tax=Clostridium difficile
QCD-32g58 RepID=UPI00006DC4EC
Length = 191
Score = 103 bits (256), Expect = 1e-20
Identities = 61/146 (41%), Positives = 84/146 (57%), Gaps = 2/146 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
D+KID+V IGSCT G+ D A++ G+KV V + P TQKV+++
Sbjct: 60 DIKIDQVVIGSCTNGRISDLEVVAEIMK--GKKVADGVRVMIFPGTQKVYLEAIE----- 112
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
K F EAG ++P+CG CLGG A + +STTNRNF GRMGH +
Sbjct: 113 ---KGYITTFIEAGAAV-STPTCGPCLGGHMGILAA---GEKSISTTNRNFVGRMGHVDS 165
Query: 177 QIYLASPYTAAASALTGRVADPREFL 100
++YLASP AAASA+TG+++ P E +
Sbjct: 166 EVYLASPAVAAASAITGKISKPSEII 191
[144][TOP]
>UniRef100_C5CJ10 Homoaconitate hydratase family protein n=1 Tax=Kosmotoga olearia
TBF 19.5.1 RepID=C5CJ10_KOSOT
Length = 417
Score = 103 bits (256), Expect = 1e-20
Identities = 56/143 (39%), Positives = 86/143 (60%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KID+V+IG+CT G+ ED AA + + V ++PA+++V++
Sbjct: 286 IKIDQVFIGTCTNGRLEDLRVAASILKGREKHPDVRLIVIPASKEVYLKALE-------- 337
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ +IF E+G T +P CG C+G L + + +ST NRNF GRMG+ + +I+
Sbjct: 338 EGLIKIFVESGA-TVLAPGCGPCVGVHQGV---LGDGERVLSTQNRNFKGRMGNPKAEIF 393
Query: 168 LASPYTAAASALTGRVADPREFL 100
LASP TAAASA+TG++ DPR+FL
Sbjct: 394 LASPATAAASAITGKITDPRKFL 416
[145][TOP]
>UniRef100_C9XME3 3-isopropylmalate dehydratase large subunit n=2 Tax=Clostridium
difficile RepID=C9XME3_CLODI
Length = 364
Score = 103 bits (256), Expect = 1e-20
Identities = 61/146 (41%), Positives = 84/146 (57%), Gaps = 2/146 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
D+KID+V IGSCT G+ D A++ G+KV V + P TQKV+++
Sbjct: 233 DIKIDQVVIGSCTNGRISDLEVVAEIMK--GKKVADGVRVMIFPGTQKVYLEAIE----- 285
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
K F EAG ++P+CG CLGG A + +STTNRNF GRMGH +
Sbjct: 286 ---KGYITTFIEAGAAV-STPTCGPCLGGHMGILAA---GEKSISTTNRNFVGRMGHVDS 338
Query: 177 QIYLASPYTAAASALTGRVADPREFL 100
++YLASP AAASA+TG+++ P E +
Sbjct: 339 EVYLASPAVAAASAITGKISKPSEII 364
[146][TOP]
>UniRef100_B1C9W1 Putative uncharacterized protein n=1 Tax=Anaerofustis
stercorihominis DSM 17244 RepID=B1C9W1_9FIRM
Length = 424
Score = 103 bits (256), Expect = 1e-20
Identities = 60/148 (40%), Positives = 83/148 (56%), Gaps = 4/148 (2%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDV----YALPVP 361
V ID+ IGSCT G+ ED AA + KV T ++PATQK+++D Y +
Sbjct: 290 VYIDQAVIGSCTNGRLEDIKMAADILRGKQVDKKVRTIVIPATQKIYLDSIKLGYVEDIV 349
Query: 360 GAGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKE 181
AG IF ++P+CG CLGG A + +STTNRNF GRMGH +
Sbjct: 350 NAGA-----IF--------STPTCGPCLGGHMGILAA---GEKAISTTNRNFVGRMGHVD 393
Query: 180 GQIYLASPYTAAASALTGRVADPREFLQ 97
++YL+SP AAASA+ G +ADP + ++
Sbjct: 394 SEVYLSSPAVAAASAIAGYIADPEKVMK 421
[147][TOP]
>UniRef100_Q0W1Q4 3-isopropylmalate dehydratase, large subunit n=1 Tax=uncultured
methanogenic archaeon RC-I RepID=Q0W1Q4_UNCMA
Length = 414
Score = 103 bits (256), Expect = 1e-20
Identities = 59/145 (40%), Positives = 81/145 (55%), Gaps = 4/145 (2%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVY----ALPVPGA 355
+D+V IGSCT G+ ED AA + GRKV+ T ++PA++ V +D A + A
Sbjct: 289 VDQVLIGSCTNGRYEDLAGAAAILK--GRKVRCRTLIIPASRSVMLDAVQTGVAADLLAA 346
Query: 354 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 175
G C +P CG CLGG A E + C++TTNRNF GRMG K
Sbjct: 347 GATIC-------------NPGCGPCLGGHMGVLA---EGEACLATTNRNFRGRMG-KGAD 389
Query: 174 IYLASPYTAAASALTGRVADPREFL 100
+YL SP TAAA+A+ G++ DPR ++
Sbjct: 390 VYLGSPLTAAATAINGKITDPRRYI 414
[148][TOP]
>UniRef100_Q18AJ2 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
difficile 630 RepID=LEUC_CLOD6
Length = 425
Score = 103 bits (256), Expect = 1e-20
Identities = 61/146 (41%), Positives = 84/146 (57%), Gaps = 2/146 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
D+KID+V IGSCT G+ D A++ G+KV V + P TQKV+++
Sbjct: 294 DIKIDQVVIGSCTNGRISDLEVVAEIMK--GKKVADGVRVMIFPGTQKVYLEAIE----- 346
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
K F EAG ++P+CG CLGG A + +STTNRNF GRMGH +
Sbjct: 347 ---KGYITTFIEAGAAV-STPTCGPCLGGHMGILAA---GEKSISTTNRNFVGRMGHVDS 399
Query: 177 QIYLASPYTAAASALTGRVADPREFL 100
++YLASP AAASA+TG+++ P E +
Sbjct: 400 EVYLASPAVAAASAITGKISKPSEII 425
[149][TOP]
>UniRef100_C8QZ84 Homoaconitate hydratase family protein n=1 Tax=Desulfurivibrio
alkaliphilus AHT2 RepID=C8QZ84_9DELT
Length = 428
Score = 102 bits (255), Expect = 1e-20
Identities = 65/144 (45%), Positives = 85/144 (59%), Gaps = 1/144 (0%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
V +D++YIGSCT G+ ED AAK+ +V L PAT KV+ A
Sbjct: 298 VPVDQIYIGSCTNGRIEDLREAAKVLKGRRIADQVRGILSPATPKVYNQ--------AME 349
Query: 348 KTCAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ +IF+EAG C T +P+CGACLG A E +VC STTNRNF GRMG K G +
Sbjct: 350 EGLLKIFQEAGFCVT--NPTCGACLGMSNGVLA---EGEVCASTTNRNFNGRMG-KGGIV 403
Query: 171 YLASPYTAAASALTGRVADPREFL 100
+L SP +AAA+A+ G++ DPR L
Sbjct: 404 HLMSPLSAAAAAVAGKITDPRPLL 427
[150][TOP]
>UniRef100_C5UT24 3-isopropylmalate dehydratase, large subunit n=1 Tax=Clostridium
botulinum E1 str. 'BoNT E Beluga' RepID=C5UT24_CLOBO
Length = 419
Score = 102 bits (255), Expect = 1e-20
Identities = 61/141 (43%), Positives = 82/141 (58%), Gaps = 2/141 (1%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPGA 355
V ID+V IGSCT G+ D A + G+KVK + ++P TQK+++ +
Sbjct: 290 VDIDQVVIGSCTNGRISDLRIARDILK--GKKVKKGIRCIVIPGTQKIYLQALEEGI--- 344
Query: 354 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 175
+ EAG ++P+CG CLGG A+ + CVSTTNRNF GRMGH E +
Sbjct: 345 -----IKDLIEAGA-VVSTPTCGPCLGGHMGILAK---GERCVSTTNRNFVGRMGHVESE 395
Query: 174 IYLASPYTAAASALTGRVADP 112
+YLASP AAASALTG++ DP
Sbjct: 396 VYLASPAVAAASALTGKITDP 416
[151][TOP]
>UniRef100_B2UYH6 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
botulinum E3 str. Alaska E43 RepID=LEUC_CLOBA
Length = 419
Score = 102 bits (255), Expect = 1e-20
Identities = 61/141 (43%), Positives = 82/141 (58%), Gaps = 2/141 (1%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPGA 355
V ID+V IGSCT G+ D A + G+KVK + ++P TQK+++ +
Sbjct: 290 VNIDQVVIGSCTNGRISDLRIARGILK--GKKVKKGIRCIVIPGTQKIYLQALEEGI--- 344
Query: 354 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 175
+ EAG ++P+CG CLGG A+ + CVSTTNRNF GRMGH E +
Sbjct: 345 -----IKDLIEAGA-VVSTPTCGPCLGGHMGILAK---GERCVSTTNRNFVGRMGHVESE 395
Query: 174 IYLASPYTAAASALTGRVADP 112
+YLASP AAASALTG++ DP
Sbjct: 396 VYLASPAVAAASALTGKITDP 416
[152][TOP]
>UniRef100_UPI00016C08CB 3-isopropylmalate dehydratase, large subunit n=1 Tax=Epulopiscium
sp. 'N.t. morphotype B' RepID=UPI00016C08CB
Length = 421
Score = 102 bits (254), Expect = 2e-20
Identities = 60/144 (41%), Positives = 85/144 (59%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
++KID+V IGSCT G+ ED A+ + G+KV V + P TQ++++D A +
Sbjct: 289 EIKIDQVVIGSCTNGRLEDLRMASDILK--GKKVAKGVRAIVFPGTQQIYLDALAEGI-- 344
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
+AGC ++P+CG CLGG A+ + VSTTNRNF GRMGH E
Sbjct: 345 ------VTNLVKAGC-VMSTPTCGPCLGGHMGILAK---GEKAVSTTNRNFVGRMGHIES 394
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
++YLASP AAASA+TG + +P +
Sbjct: 395 EVYLASPAVAAASAITGYITNPEK 418
[153][TOP]
>UniRef100_A5D4W1 3-isopropylmalate dehydratase large subunit n=1 Tax=Pelotomaculum
thermopropionicum SI RepID=A5D4W1_PELTS
Length = 420
Score = 102 bits (254), Expect = 2e-20
Identities = 60/144 (41%), Positives = 85/144 (59%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKV--KVPTFLVPATQKVWMDVYALPVPG 358
+++ID+V IGSCT G+ ED AA++ GRKV V + P T K+++
Sbjct: 289 NIEIDQVVIGSCTNGRMEDLREAARVLK--GRKVHKNVRLIIFPGTPKIYLQALR----- 341
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
+ + F EAG ++P+CG CLGG + AR + CV+TTNRNF GRMGH E
Sbjct: 342 ---EGLIETFVEAG-GVVSTPTCGPCLGGHSGILAR---GERCVATTNRNFVGRMGHPES 394
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
++YL++P AAASA+ GR+ P E
Sbjct: 395 EVYLSNPAVAAASAVLGRIGGPWE 418
[154][TOP]
>UniRef100_C1TNL5 3-isopropylmalate dehydratase, large subunit n=1
Tax=Dethiosulfovibrio peptidovorans DSM 11002
RepID=C1TNL5_9BACT
Length = 419
Score = 102 bits (254), Expect = 2e-20
Identities = 59/142 (41%), Positives = 80/142 (56%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
D +I +V+IGSCT G+ ED AAA + V ++PA+ +V+
Sbjct: 287 DTEIQQVFIGSCTNGRLEDMAAAASVLEGKKVHPSVRCIVIPASYEVYNACLE------- 339
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
K + F EAG +P+CG CLGG A E + CVST+NRNF GRMGH + ++
Sbjct: 340 -KGYIRTFTEAGAAV-CTPTCGPCLGGHMGILA---EGERCVSTSNRNFVGRMGHPKSEV 394
Query: 171 YLASPYTAAASALTGRVADPRE 106
YLASP TAA SA+ G +ADP +
Sbjct: 395 YLASPVTAAWSAVKGHIADPAQ 416
[155][TOP]
>UniRef100_A8RZ58 Putative uncharacterized protein n=1 Tax=Clostridium bolteae ATCC
BAA-613 RepID=A8RZ58_9CLOT
Length = 420
Score = 102 bits (254), Expect = 2e-20
Identities = 60/142 (42%), Positives = 85/142 (59%), Gaps = 2/142 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
+VK+D+ IGSCT G+ ED AA++ GRK+ V ++PATQ +++
Sbjct: 289 EVKVDQAVIGSCTNGRIEDMRIAAEVLK--GRKIAKGVRCIVIPATQSIYLQ-------- 338
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
A + +IF EAG ++P+CG CLGG A + C+STTNRNF GRMGH +
Sbjct: 339 AMKEGLLEIFIEAGA-VVSTPTCGPCLGGYMGILAA---GERCISTTNRNFVGRMGHVDS 394
Query: 177 QIYLASPYTAAASALTGRVADP 112
++YLASP AAASA+ G++ P
Sbjct: 395 EVYLASPAVAAASAVAGKIICP 416
[156][TOP]
>UniRef100_A7VIP8 Putative uncharacterized protein n=1 Tax=Clostridium sp. L2-50
RepID=A7VIP8_9CLOT
Length = 441
Score = 102 bits (254), Expect = 2e-20
Identities = 58/142 (40%), Positives = 80/142 (56%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
D+KID+V IGSCT G+ D AA + V ++P TQ+V++
Sbjct: 309 DIKIDQVVIGSCTNGRISDMRIAADIIKGRQVAPGVRVIVIPGTQEVYLQCIE------- 361
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ IF +AG ++P+CG CLGG A + VSTTNRNF GRMGH + ++
Sbjct: 362 -EGLMTIFVKAGA-VVSTPTCGPCLGGHMGVMAA---GERAVSTTNRNFVGRMGHVDSEV 416
Query: 171 YLASPYTAAASALTGRVADPRE 106
YLASP AAASA+TG+++ P E
Sbjct: 417 YLASPAVAAASAITGKISSPEE 438
[157][TOP]
>UniRef100_Q46B45 3-isopropylmalate dehydratase, large subunit n=1 Tax=Methanosarcina
barkeri str. Fusaro RepID=Q46B45_METBF
Length = 413
Score = 102 bits (254), Expect = 2e-20
Identities = 64/138 (46%), Positives = 81/138 (58%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKT 343
ID+V+IG+CT G+ ED AA + G+KV V T ++PA++ + A
Sbjct: 289 IDQVFIGTCTNGRLEDLEVAAAILK--GKKVAVRTIVIPASRTTLL--------AAIENG 338
Query: 342 CAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYLA 163
+I +AG T A+P CG CLG L E +VC+ST NRNF GRMG K G IYLA
Sbjct: 339 TMEILLKAGI-TLATPGCGPCLGAHQGV---LGEGEVCLSTANRNFKGRMG-KSGFIYLA 393
Query: 162 SPYTAAASALTGRVADPR 109
SP TAAASAL G + DPR
Sbjct: 394 SPATAAASALAGEITDPR 411
[158][TOP]
>UniRef100_A9KT79 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
phytofermentans ISDg RepID=LEUC_CLOPH
Length = 421
Score = 102 bits (254), Expect = 2e-20
Identities = 61/144 (42%), Positives = 84/144 (58%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
+V+ID+V IGSCT G+ D AAK+ GRKV + + PATQ +++
Sbjct: 289 EVRIDQVVIGSCTNGRIGDLRIAAKVLE--GRKVAKGMRAIVFPATQAIYLQAIE----- 341
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
+ Q F +AGC ++P+CG CLGG A + STTNRNF GRMGH E
Sbjct: 342 ---EGLIQTFIKAGC-VVSTPTCGPCLGGHMGILAA---GERAASTTNRNFVGRMGHVES 394
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
++YL SP AAASA+TG++++P E
Sbjct: 395 EVYLCSPAVAAASAVTGKISEPSE 418
[159][TOP]
>UniRef100_B2TIQ9 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
botulinum B str. Eklund 17B RepID=LEUC_CLOBB
Length = 419
Score = 102 bits (254), Expect = 2e-20
Identities = 60/142 (42%), Positives = 82/142 (57%), Gaps = 2/142 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
D+ ID+V IGSCT G+ D A + G+KVK + ++P TQ +++ +
Sbjct: 289 DIDIDQVVIGSCTNGRISDLRIARDILK--GKKVKKGIRCIVIPGTQNIYLQALEEGI-- 344
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
+ EAG ++P+CG CLGG A+ + CVSTTNRNF GRMGH E
Sbjct: 345 ------IKDLIEAGV-VVSTPTCGPCLGGHMGILAK---GERCVSTTNRNFVGRMGHVES 394
Query: 177 QIYLASPYTAAASALTGRVADP 112
++YLASP AAASALTG++ DP
Sbjct: 395 EVYLASPAVAAASALTGKITDP 416
[160][TOP]
>UniRef100_A7HZP6 3-isopropylmalate dehydratase large subunit n=1 Tax=Campylobacter
hominis ATCC BAA-381 RepID=LEUC_CAMHC
Length = 419
Score = 102 bits (254), Expect = 2e-20
Identities = 61/143 (42%), Positives = 85/143 (59%), Gaps = 2/143 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLV--PATQKVWMDVYALPVPG 358
++KID+ +IGSCT G+ D AA++ G+KV T L+ PATQK++
Sbjct: 290 ELKIDQAFIGSCTNGRLSDLRIAAEILK--GKKVAKKTRLIITPATQKIYK--------A 339
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
A + IF +AG ++P+CGACLGG L + CVSTTNRNF GRMG +
Sbjct: 340 AEHEGLIDIFIDAGA-VVSNPTCGACLGGYMGI---LGANERCVSTTNRNFVGRMGDRTS 395
Query: 177 QIYLASPYTAAASALTGRVADPR 109
++YLA+ AASA+TG++ DPR
Sbjct: 396 EVYLANSAVVAASAITGKITDPR 418
[161][TOP]
>UniRef100_Q9UZ07 3-isopropylmalate dehydratase large subunit 1 n=1 Tax=Pyrococcus
abyssi RepID=LEUC1_PYRAB
Length = 423
Score = 102 bits (254), Expect = 2e-20
Identities = 61/147 (41%), Positives = 85/147 (57%), Gaps = 2/147 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
++KID+V+IGSCT G+ ED AA++ G+KV V ++P + V+
Sbjct: 291 NIKIDQVFIGSCTNGRIEDLRMAAEILE--GQKVAKWVRLIVIPCSPTVYWKALK----- 343
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
+ +IF EAG P+CG CLGG A + VSTTNRNF GRMGH +
Sbjct: 344 ---EGLIEIFLEAGA-VIGPPTCGPCLGGHMGVLA---SGERAVSTTNRNFVGRMGHPKS 396
Query: 177 QIYLASPYTAAASALTGRVADPREFLQ 97
++YLA+PY AAASA+ GR+A P E ++
Sbjct: 397 EVYLANPYVAAASAVLGRIASPEEVVK 423
[162][TOP]
>UniRef100_B3E9Z6 Homoaconitate hydratase family protein n=1 Tax=Geobacter lovleyi SZ
RepID=B3E9Z6_GEOLS
Length = 427
Score = 102 bits (253), Expect = 2e-20
Identities = 62/145 (42%), Positives = 86/145 (59%), Gaps = 1/145 (0%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
D ++D++Y+GSCT G+ ED AA++ V L PAT K++ D A
Sbjct: 297 DSRVDQIYLGSCTNGRLEDLRIAAQILKGNKLAEHVRGILSPATPKIYRD--------AM 348
Query: 351 GKTCAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 175
+ IF +AG C T + +CGACLG A + +VC STTNRNF GRMG K G
Sbjct: 349 KEGLIDIFLDAGFCVT--NSTCGACLGMSNGVLA---DGEVCASTTNRNFNGRMG-KGGM 402
Query: 174 IYLASPYTAAASALTGRVADPREFL 100
++L SP TAAA+A+ G++ADPR++L
Sbjct: 403 VHLMSPATAAATAIEGKIADPRKYL 427
[163][TOP]
>UniRef100_C5ZZ28 3-isopropylmalate dehydratase, large subunit n=1 Tax=Helicobacter
canadensis MIT 98-5491 RepID=C5ZZ28_9HELI
Length = 421
Score = 102 bits (253), Expect = 2e-20
Identities = 57/142 (40%), Positives = 82/142 (57%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
D+KID+V+IGSCT G+ D A+++ V + P TQ+++ + Y L
Sbjct: 292 DLKIDQVFIGSCTNGRLADLKIASEILKGKKVHKDVRLIVTPGTQQIYKEAYQLGY---- 347
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
I E+G ++P+CGACLGG L + + CVSTTNRNF GRMG + ++
Sbjct: 348 ----IDILLESGA-LISNPTCGACLGGYMGI---LGDNERCVSTTNRNFVGRMGARSSEV 399
Query: 171 YLASPYTAAASALTGRVADPRE 106
YLA+ AA SA+ G++ADPRE
Sbjct: 400 YLANSAVAAMSAIKGQIADPRE 421
[164][TOP]
>UniRef100_C5F2A2 3-isopropylmalate dehydratase large subunit n=1 Tax=Helicobacter
pullorum MIT 98-5489 RepID=C5F2A2_9HELI
Length = 422
Score = 102 bits (253), Expect = 2e-20
Identities = 57/142 (40%), Positives = 81/142 (57%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
D+KID+V+IGSCT G+ D A+++ V + P TQ ++ + + L
Sbjct: 292 DLKIDQVFIGSCTNGRLSDLKIASEILKGKKVHQDVRLIITPGTQNIYKEAHKLGY---- 347
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
I EAG ++P+CGACLGG L + + CVSTTNRNF GRMG + ++
Sbjct: 348 ----IDILLEAGA-LISNPTCGACLGGYMGI---LGDNERCVSTTNRNFVGRMGARNSEV 399
Query: 171 YLASPYTAAASALTGRVADPRE 106
YLA+ AA SA+ G++ADPRE
Sbjct: 400 YLANSAVAAISAIKGKIADPRE 421
[165][TOP]
>UniRef100_A8SZ55 Putative uncharacterized protein n=1 Tax=Coprococcus eutactus ATCC
27759 RepID=A8SZ55_9FIRM
Length = 461
Score = 102 bits (253), Expect = 2e-20
Identities = 61/144 (42%), Positives = 83/144 (57%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
D+KID+V IGSCT G+ D AA + GRKV V ++P TQ +++
Sbjct: 329 DIKIDQVVIGSCTNGRISDMRIAADIIK--GRKVADGVRVIVIPGTQDIYLQCIE----- 381
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
+ IF +AG ++P+CG CLGG A + VSTTNRNF GRMGH +
Sbjct: 382 ---EGLMTIFVKAGA-VVSTPTCGPCLGGHMGVMAA---GERAVSTTNRNFVGRMGHVDS 434
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
++YLASP AAASA+TG+++ P E
Sbjct: 435 EVYLASPAVAAASAITGKISSPDE 458
[166][TOP]
>UniRef100_B4U7U5 3-isopropylmalate dehydratase large subunit n=1
Tax=Hydrogenobaculum sp. Y04AAS1 RepID=LEUC_HYDS0
Length = 424
Score = 102 bits (253), Expect = 2e-20
Identities = 60/143 (41%), Positives = 83/143 (58%), Gaps = 2/143 (1%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPT--FLVPATQKVWMDVYALPVPGA 355
+ ID+ +IGSCT G+ ED AA + G+KV T ++PA++ V++ A
Sbjct: 289 ITIDQAFIGSCTNGRIEDLRIAASILK--GKKVHPYTRCVVIPASKNVYLQ--------A 338
Query: 354 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 175
+ IF EAGC S +CG CLGG A+ + C+ST+NRNFPGRMGH + +
Sbjct: 339 LHEGLVDIFIEAGCAVSTS-TCGPCLGGHMGILAK---GERCISTSNRNFPGRMGHPQSE 394
Query: 174 IYLASPYTAAASALTGRVADPRE 106
YLA+P AASA+ GR+A P E
Sbjct: 395 AYLANPAVVAASAVLGRIAHPEE 417
[167][TOP]
>UniRef100_Q97EE0 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
acetobutylicum RepID=LEUC_CLOAB
Length = 422
Score = 102 bits (253), Expect = 2e-20
Identities = 57/144 (39%), Positives = 81/144 (56%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
+V +D+V IGSCT G+ ED AA + K + + P TQ ++++ A
Sbjct: 291 EVNVDQVVIGSCTNGRMEDLRIAASILKGKKIKKGIRLIVFPGTQNIYLE--------AM 342
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ + F EAG ++P+CG CLGG A E + +STTNRNF GRMGH + ++
Sbjct: 343 EEGLVRTFIEAG-GIVSTPTCGPCLGGHMGILA---EGERAISTTNRNFVGRMGHPKSEV 398
Query: 171 YLASPYTAAASALTGRVADPREFL 100
YLASP AAASA+ G++ P E L
Sbjct: 399 YLASPAVAAASAIAGKIVSPEEVL 422
[168][TOP]
>UniRef100_Q8U2A1 3-isopropylmalate dehydratase large subunit 1 n=1 Tax=Pyrococcus
furiosus RepID=LEUC1_PYRFU
Length = 424
Score = 102 bits (253), Expect = 2e-20
Identities = 63/147 (42%), Positives = 85/147 (57%), Gaps = 2/147 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
++KID+V IGSCT G+ ED AA++ G+KV V ++P + V+
Sbjct: 292 NIKIDQVVIGSCTNGRLEDLRMAAEVLE--GQKVAPWVRLIILPCSPTVYFK-------- 341
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
A + +IF EAG P+CG CLGG A + VSTTNRNF GRMGH +
Sbjct: 342 AMKEGLLEIFLEAGA-VIGPPTCGPCLGGHMGILA---SGERAVSTTNRNFVGRMGHPKS 397
Query: 177 QIYLASPYTAAASALTGRVADPREFLQ 97
++YLASPY AAASA+ GR+A P E ++
Sbjct: 398 EVYLASPYVAAASAILGRIASPEEVVK 424
[169][TOP]
>UniRef100_C5EK99 3-isopropylmalate dehydratase n=1 Tax=Clostridiales bacterium
1_7_47FAA RepID=C5EK99_9FIRM
Length = 419
Score = 101 bits (252), Expect = 3e-20
Identities = 58/144 (40%), Positives = 79/144 (54%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
++K+++ YIGSCTGG+ ED AA++ +VPA+ +V +
Sbjct: 288 EMKLNQGYIGSCTGGREEDIAVAARIVKGRHIPPYSRLVVVPASSEVMLSCME------- 340
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
K Q AG T +P CGACLG A + C+S+TNRNFPGRMG + I
Sbjct: 341 -KGYIQDLMNAGA-TITTPGCGACLGAHEGIIA---PGETCISSTNRNFPGRMGSNQASI 395
Query: 171 YLASPYTAAASALTGRVADPREFL 100
YLASP T AAS + GR+ DPR++L
Sbjct: 396 YLASPATVAASIINGRITDPRDYL 419
[170][TOP]
>UniRef100_Q2RG98 3-isopropylmalate dehydratase large subunit n=1 Tax=Moorella
thermoacetica ATCC 39073 RepID=LEUC_MOOTA
Length = 421
Score = 101 bits (252), Expect = 3e-20
Identities = 57/145 (39%), Positives = 83/145 (57%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
++KID+V IGSCT G+ ED AA++ +V ++P TQ+++ A
Sbjct: 289 EIKIDQVVIGSCTNGRLEDLRVAAQILKGQKVHPEVRLIVIPGTQQIYAAALA------- 341
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ F EAG ++P+CG CLGG A+ + ++TTNRNF GRMGH E ++
Sbjct: 342 -EGLIATFIEAGAAV-STPTCGPCLGGHMGILAK---GERALATTNRNFVGRMGHPESEV 396
Query: 171 YLASPYTAAASALTGRVADPREFLQ 97
YLA P AAASA+ GR+A P E ++
Sbjct: 397 YLAGPAVAAASAVKGRIAAPEEVVK 421
[171][TOP]
>UniRef100_A7ZFP0 3-isopropylmalate dehydratase large subunit n=1 Tax=Campylobacter
concisus 13826 RepID=LEUC_CAMC1
Length = 421
Score = 101 bits (252), Expect = 3e-20
Identities = 62/144 (43%), Positives = 84/144 (58%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLV--PATQKVWMDVYALPVPG 358
D+ ID+ +IGSCT G+ D AA++ G+KV T L+ PATQK+
Sbjct: 291 DLAIDQAFIGSCTNGRLSDLRIAAQILK--GKKVARKTRLIITPATQKI--------ARA 340
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
A + IF EAG ++P+CGACLGG L + C+STTNRNF GRMG +
Sbjct: 341 AEKEGLIDIFIEAGA-VVSNPTCGACLGGYMGI---LGANERCISTTNRNFVGRMGDRTS 396
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
+IYLA+ AASA+ G++ADPR+
Sbjct: 397 EIYLANSAVVAASAIAGKIADPRD 420
[172][TOP]
>UniRef100_C9KK15 Homoaconitate hydratase n=1 Tax=Mitsuokella multacida DSM 20544
RepID=C9KK15_9FIRM
Length = 423
Score = 101 bits (251), Expect = 4e-20
Identities = 63/143 (44%), Positives = 83/143 (58%), Gaps = 2/143 (1%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPT--FLVPATQKVWMDVYALPVPGAGG 349
+D+ Y+GSCTGG+TEDF AAK+ AG+ + T +VPA++ V + A
Sbjct: 288 VDQAYLGSCTGGRTEDFAVAAKIL--AGQHIPAGTRMVMVPASKAVLAECLA-------- 337
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
K Q AG AS C ACLG A +VC+S+TNRNFPGRMG +G+IY
Sbjct: 338 KGYIQTLLAAGATLTAS-GCAACLGIHQGLLAA---DEVCLSSTNRNFPGRMGSVKGRIY 393
Query: 168 LASPYTAAASALTGRVADPREFL 100
L SP + AA+A G V DPR++L
Sbjct: 394 LGSPASVAAAARNGVVTDPRQYL 416
[173][TOP]
>UniRef100_B0A9M7 Putative uncharacterized protein n=1 Tax=Clostridium bartlettii DSM
16795 RepID=B0A9M7_9CLOT
Length = 429
Score = 101 bits (251), Expect = 4e-20
Identities = 61/144 (42%), Positives = 81/144 (56%), Gaps = 2/144 (1%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPG 358
D+KID+V IGSCT G+ ED AA++ G+KV V + P TQ ++++
Sbjct: 294 DIKIDQVVIGSCTNGRIEDMRIAAEIMR--GKKVADDVRCIVFPGTQAIYLEAIEK---- 347
Query: 357 AGGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEG 178
G + A TP +CG CLGG A + VSTTNRNF GRMGH E
Sbjct: 348 --GYITDMVLAGAAISTP---TCGPCLGGHMGILAA---GERAVSTTNRNFVGRMGHTES 399
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
++YLASP AAASA+TG+++ P E
Sbjct: 400 EVYLASPAVAAASAITGKISSPSE 423
[174][TOP]
>UniRef100_A7VNU8 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
RepID=A7VNU8_9CLOT
Length = 428
Score = 101 bits (251), Expect = 4e-20
Identities = 60/141 (42%), Positives = 78/141 (55%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
VKID+V IGSCT G+ D AA L V + P TQ +++D A
Sbjct: 290 VKIDQVVIGSCTNGRLSDLRIAANLLKGKKVAKNVRCIVFPGTQTIYLD--------AMR 341
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ + F +AG ++P+CG CLGG A + VSTTNRNF GRMGH + ++Y
Sbjct: 342 EGLVEAFIQAGA-VVSTPTCGPCLGGHMGILAA---GERAVSTTNRNFVGRMGHVDSEVY 397
Query: 168 LASPYTAAASALTGRVADPRE 106
LASP AAASA+TG + DP E
Sbjct: 398 LASPAVAAASAVTGYITDPAE 418
[175][TOP]
>UniRef100_A1HRB9 Homoaconitate hydratase family protein n=1 Tax=Thermosinus
carboxydivorans Nor1 RepID=A1HRB9_9FIRM
Length = 420
Score = 101 bits (251), Expect = 4e-20
Identities = 63/143 (44%), Positives = 80/143 (55%), Gaps = 2/143 (1%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPGAGG 349
I + YIGSCTGG+ D AAA++ GRKV V + PA+ ++W A
Sbjct: 292 IHQAYIGSCTGGRYNDLAAAARVLK--GRKVANGVRLLVSPASHEIWRQ--------AAA 341
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
I EAG A P+CG C+G + A + + C+S+TNRNF GRMG K IY
Sbjct: 342 DGILSILAEAGAIILA-PTCGVCVGLHSGLLA---DGEYCISSTNRNFIGRMGSKNAGIY 397
Query: 168 LASPYTAAASALTGRVADPREFL 100
LASP AASA+TG + DPREFL
Sbjct: 398 LASPMAVAASAITGVITDPREFL 420
[176][TOP]
>UniRef100_B8CX22 3-isopropylmalate dehydratase large subunit n=1 Tax=Halothermothrix
orenii H 168 RepID=LEUC_HALOH
Length = 420
Score = 101 bits (251), Expect = 4e-20
Identities = 58/144 (40%), Positives = 79/144 (54%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
D+KID+ IGSCT G+ ED AA + V ++P TQ ++
Sbjct: 289 DIKIDQAVIGSCTNGRMEDLRIAAGILKEKQVHHDVRCIVIPGTQDIYKQALK------- 341
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ +IF EAG ++P+CG CLGG AR + ++TTNRNF GRMGH E ++
Sbjct: 342 -EGLIEIFIEAGAAV-STPTCGPCLGGHMGILAR---GEKAIATTNRNFVGRMGHPESEV 396
Query: 171 YLASPYTAAASALTGRVADPREFL 100
YLA+P AAASA+ G +A P E L
Sbjct: 397 YLANPAVAAASAIKGYIAHPEEVL 420
[177][TOP]
>UniRef100_C9RAX0 3-isopropylmalate dehydratase, large subunit n=1 Tax=Ammonifex
degensii KC4 RepID=C9RAX0_9THEO
Length = 421
Score = 100 bits (250), Expect = 5e-20
Identities = 61/146 (41%), Positives = 86/146 (58%), Gaps = 2/146 (1%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPGA 355
+ ID+V IGSCT G+ ED AA++ G+KV V ++P TQ+++
Sbjct: 289 ITIDQVVIGSCTNGRLEDLRVAAQVLK--GKKVHPYVRLIVIPGTQEIYRQALR------ 340
Query: 354 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 175
+ +IF EAG ++P+CG CLGG A+ + V+TTNRNF GRMGH E +
Sbjct: 341 --EGLIEIFLEAG-GAVSTPTCGPCLGGHMGVLAK---GERAVATTNRNFVGRMGHPESE 394
Query: 174 IYLASPYTAAASALTGRVADPREFLQ 97
+YLASP AAASA+ GR+A P E ++
Sbjct: 395 VYLASPAVAAASAVLGRLAHPDEVVK 420
[178][TOP]
>UniRef100_B0MLF2 Putative uncharacterized protein n=1 Tax=Eubacterium siraeum DSM
15702 RepID=B0MLF2_9FIRM
Length = 418
Score = 100 bits (250), Expect = 5e-20
Identities = 56/137 (40%), Positives = 78/137 (56%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
D+KID+ IGSCT G+ D AA++ V ++P TQKV++
Sbjct: 290 DIKIDQAVIGSCTNGRISDMRIAAEILKGKHIAKGVRCIVIPGTQKVYLQCIK------- 342
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ A+IF AGC ++P+CG CLGG A + +STTNRNF GRMGH + ++
Sbjct: 343 -EGLAEIFVNAGC-VLSTPTCGPCLGGHMGILAA---GERAISTTNRNFVGRMGHVDSEV 397
Query: 171 YLASPYTAAASALTGRV 121
YLASP AAASA+ G++
Sbjct: 398 YLASPAVAAASAIAGKI 414
[179][TOP]
>UniRef100_A4WMI6 3-isopropylmalate dehydratase large subunit n=1 Tax=Pyrobaculum
arsenaticum DSM 13514 RepID=LEUC_PYRAR
Length = 415
Score = 100 bits (250), Expect = 5e-20
Identities = 57/144 (39%), Positives = 83/144 (57%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
V++D+V+IGSCT G+ D AA++ GR+VK +PA+ +V+ L
Sbjct: 285 VEVDQVFIGSCTNGRLRDIATAARILK--GRRVKTRCIAIPASYEVFKTAMKLGY----- 337
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ EAGC +CG CLGG + +V ++T+NRNF GR+GH E +IY
Sbjct: 338 ---IDVLTEAGCVVTYG-TCGPCLGGH---FGVAGPGEVHLTTSNRNFKGRVGHPEAKIY 390
Query: 168 LASPYTAAASALTGRVADPREFLQ 97
LA+P AAA+A GR+ADPR +L+
Sbjct: 391 LANPAVAAATAAEGRIADPRPYLK 414
[180][TOP]
>UniRef100_Q2KVM0 3-isopropylmalate dehydratase large subunit n=1 Tax=Bordetella
avium 197N RepID=Q2KVM0_BORA1
Length = 422
Score = 100 bits (249), Expect = 6e-20
Identities = 61/144 (42%), Positives = 77/144 (53%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
DV + YIG+CTG K ED AAA + + + PA+Q+ A V
Sbjct: 291 DVPLQVAYIGACTGAKLEDLRAAASVLRGRRLAAGMRLMVAPASQQDQRQAEAEGV---- 346
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
Q EAG D A+ SCGAC G + + +STT RNF GRMG + Q+
Sbjct: 347 ----MQALREAGADVLAT-SCGACAGYGGS----IPDGASVISTTARNFKGRMGSETAQV 397
Query: 171 YLASPYTAAASALTGRVADPREFL 100
YLASPYT AASA+ GR+ADPREF+
Sbjct: 398 YLASPYTVAASAVAGRIADPREFM 421
[181][TOP]
>UniRef100_A6DDD6 3-ISOPROPYLMALATE DEHYDRATASE, LARGE SUBUNIT n=1 Tax=Caminibacter
mediatlanticus TB-2 RepID=A6DDD6_9PROT
Length = 425
Score = 100 bits (249), Expect = 6e-20
Identities = 57/142 (40%), Positives = 80/142 (56%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
D++I +VYIGSCT G D AA + +V + PATQ+++ A
Sbjct: 295 DIEIHQVYIGSCTNGTLSDLRTAANILKGKRVHKRVRLIVTPATQRIYKQ--------AE 346
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ +AG A+P+CGACLGG L + + CV+TTNRNF GRMG + +I
Sbjct: 347 HEGIIDTLIDAGA-VVANPTCGACLGGYMGI---LGDGERCVATTNRNFRGRMGSRSSEI 402
Query: 171 YLASPYTAAASALTGRVADPRE 106
YL++ AAASA+ G++ADPRE
Sbjct: 403 YLSNSAVAAASAIAGKIADPRE 424
[182][TOP]
>UniRef100_A4XJ48 3-isopropylmalate dehydratase large subunit n=1
Tax=Caldicellulosiruptor saccharolyticus DSM 8903
RepID=LEUC_CALS8
Length = 429
Score = 100 bits (249), Expect = 6e-20
Identities = 60/143 (41%), Positives = 82/143 (57%), Gaps = 2/143 (1%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPGA 355
+ ID+V IGSCT G+ ED AAK+ GRKVK + + PATQ ++
Sbjct: 293 IYIDQVVIGSCTNGRIEDLRIAAKILK--GRKVKKGLRCIIFPATQNIYKQALK------ 344
Query: 354 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 175
+ +IF +AGC ++P+CG CLGG A E + ++TTNRNF GRMGH +
Sbjct: 345 --EGLIEIFIDAGC-VVSTPTCGPCLGGHMGILA---EGERALATTNRNFVGRMGHPNSE 398
Query: 174 IYLASPYTAAASALTGRVADPRE 106
+YL+SP AAASA+ G + P E
Sbjct: 399 VYLSSPAIAAASAVLGYIGSPEE 421
[183][TOP]
>UniRef100_Q8TLF1 3-isopropylmalate dehydratase large subunit 1 n=1
Tax=Methanosarcina acetivorans RepID=LEUC1_METAC
Length = 424
Score = 100 bits (249), Expect = 6e-20
Identities = 63/138 (45%), Positives = 81/138 (58%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKT 343
+D+V+IG+CT G+ ED AA + G++V V T ++PA++ + A
Sbjct: 300 VDQVFIGTCTNGRLEDLEVAAAVLK--GKQVAVRTIVIPASRTTLL--------AAIENG 349
Query: 342 CAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYLA 163
+ +AG T A+P CG CLG L E +VCVST NRNF GRMG K G IYLA
Sbjct: 350 TMETLLKAGV-TLATPGCGPCLGAHQGV---LGEGEVCVSTANRNFKGRMG-KGGFIYLA 404
Query: 162 SPYTAAASALTGRVADPR 109
SP TAAASALTG + DPR
Sbjct: 405 SPATAAASALTGEITDPR 422
[184][TOP]
>UniRef100_B5IEF0 Homoaconitate hydratase family protein n=1 Tax=Aciduliprofundum
boonei T469 RepID=B5IEF0_9EURY
Length = 418
Score = 100 bits (248), Expect = 8e-20
Identities = 56/143 (39%), Positives = 79/143 (55%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+++++V++G+CT G+ ED AA++ V + PA+ VW + A
Sbjct: 288 IEVNQVFLGTCTNGRVEDLEVAARILKGNKVNKNVRMLVFPASWDVWRE--------ANE 339
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
K + EAG +P CG CLG A A + + C+ST NRNF GRMG+ +IY
Sbjct: 340 KGILRTLAEAGA-VIMNPGCGPCLGAHAGVLA---DGEKCLSTANRNFKGRMGNPNAEIY 395
Query: 168 LASPYTAAASALTGRVADPREFL 100
L SP TAAA+AL G +ADPRE L
Sbjct: 396 LGSPATAAATALKGYIADPREVL 418
[185][TOP]
>UniRef100_B5ICW8 Homoaconitate hydratase family protein n=1 Tax=Aciduliprofundum
boonei T469 RepID=B5ICW8_9EURY
Length = 419
Score = 100 bits (248), Expect = 8e-20
Identities = 56/144 (38%), Positives = 83/144 (57%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
+++ID+VYIG+CT G+ ED AAK+ K ++PA+++V++
Sbjct: 288 NIRIDQVYIGTCTNGRIEDLRVAAKILDGNKVNKKTRLIVIPASRRVYIQALK------- 340
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ + F EAG SP CG C+G A + + +ST NRNF GRMG+ +I
Sbjct: 341 -EGLLEKFVEAGAAIE-SPGCGPCVGIHKGVLA---DGERVLSTQNRNFKGRMGNPNAEI 395
Query: 171 YLASPYTAAASALTGRVADPREFL 100
YL SP TAAA+A+ G++ADPRE+L
Sbjct: 396 YLGSPATAAATAIEGKIADPREYL 419
[186][TOP]
>UniRef100_B5IBC4 Homoaconitate hydratase family protein n=1 Tax=Aciduliprofundum
boonei T469 RepID=B5IBC4_9EURY
Length = 419
Score = 100 bits (248), Expect = 8e-20
Identities = 56/144 (38%), Positives = 83/144 (57%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
+++ID+VYIG+CT G+ ED AAK+ K ++PA+++V++
Sbjct: 288 NIRIDQVYIGTCTNGRIEDLRVAAKILDGNKVNKKTRLIVIPASRRVYIQALK------- 340
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ + F EAG SP CG C+G A + + +ST NRNF GRMG+ +I
Sbjct: 341 -EGLLEKFVEAGAAIE-SPGCGPCVGIHKGVLA---DGERVLSTQNRNFKGRMGNPNAEI 395
Query: 171 YLASPYTAAASALTGRVADPREFL 100
YL SP TAAA+A+ G++ADPRE+L
Sbjct: 396 YLGSPATAAATAIEGKIADPREYL 419
[187][TOP]
>UniRef100_Q7M9Z9 3-isopropylmalate dehydratase large subunit n=1 Tax=Wolinella
succinogenes RepID=LEUC_WOLSU
Length = 422
Score = 100 bits (248), Expect = 8e-20
Identities = 56/142 (39%), Positives = 80/142 (56%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
D+KID+ +IGSCT G+ D AA++ V + P TQ+++ D +
Sbjct: 292 DLKIDQAFIGSCTNGRLSDLRIAAQILKGKRVHPDVRLIITPGTQQIYKDAHQ------- 344
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ EAG ++P+CGACLGG L + + CVSTTNRNF GRMG + ++
Sbjct: 345 -EGLIDTLLEAGA-LISNPTCGACLGGYMGI---LGDNERCVSTTNRNFVGRMGARSSEV 399
Query: 171 YLASPYTAAASALTGRVADPRE 106
YLA+ AAASAL G++ DPR+
Sbjct: 400 YLANSAVAAASALKGKITDPRK 421
[188][TOP]
>UniRef100_B5YKE0 3-isopropylmalate dehydratase large subunit n=1
Tax=Thermodesulfovibrio yellowstonii DSM 11347
RepID=LEUC_THEYD
Length = 421
Score = 100 bits (248), Expect = 8e-20
Identities = 59/143 (41%), Positives = 83/143 (58%), Gaps = 2/143 (1%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKV--KVPTFLVPATQKVWMDVYALPVPGA 355
+KID+V IGSCT G+ ED AA + GRKV +V ++PATQK++M
Sbjct: 290 IKIDQVVIGSCTNGRLEDLREAAMVLK--GRKVHPEVRMIIIPATQKIYMQALK------ 341
Query: 354 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 175
+ +IF +A + P+CG CLGG A+ + ++TTNRNF GRMGH E +
Sbjct: 342 --EGLIEIFIDAQA-VVSPPTCGPCLGGHMGILAK---GERAIATTNRNFVGRMGHPESE 395
Query: 174 IYLASPYTAAASALTGRVADPRE 106
+YL++P AAAS + GR+ P E
Sbjct: 396 VYLSNPAVAAASGVLGRIGTPEE 418
[189][TOP]
>UniRef100_B2V844 3-isopropylmalate dehydratase large subunit n=1
Tax=Sulfurihydrogenibium sp. YO3AOP1 RepID=LEUC_SULSY
Length = 431
Score = 100 bits (248), Expect = 8e-20
Identities = 57/139 (41%), Positives = 81/139 (58%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKT 343
ID+V+IGSCT G+ D AA + + +V ++PA+ +++ A +
Sbjct: 292 IDQVFIGSCTNGRLSDLRIAAAILKSKKVHPEVRCIVIPASDQIYKQ--------ALHEG 343
Query: 342 CAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYLA 163
+I +AGC S +CG CLGG A E +VC+ST+NRNF GRMGH + Q+YL+
Sbjct: 344 IIEILADAGCLISTS-TCGPCLGGHMGILA---EGEVCLSTSNRNFVGRMGHPKSQVYLS 399
Query: 162 SPYTAAASALTGRVADPRE 106
SP AAASA+ GR+A P E
Sbjct: 400 SPAVAAASAVLGRIAHPDE 418
[190][TOP]
>UniRef100_Q8ZW41 3-isopropylmalate dehydratase large subunit n=1 Tax=Pyrobaculum
aerophilum RepID=LEUC_PYRAE
Length = 415
Score = 100 bits (248), Expect = 8e-20
Identities = 57/144 (39%), Positives = 83/144 (57%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
V++D+V+IGSCT G+ D AAK+ GR+VK +PA+ +V+ L
Sbjct: 285 VEVDQVFIGSCTNGRLSDIAVAAKILK--GRRVKSRCIAIPASYEVFRRAMKLGY----- 337
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ EAGC +CG CLGG + +V V+T+NRNF GR+GH + +IY
Sbjct: 338 ---IDVLTEAGCVVTYG-TCGPCLGGH---FGVAGPGEVVVTTSNRNFRGRVGHPDAKIY 390
Query: 168 LASPYTAAASALTGRVADPREFLQ 97
LA+P AAA+A G++ADPR +L+
Sbjct: 391 LANPAVAAATAAEGKIADPRPYLR 414
[191][TOP]
>UniRef100_C1DUH4 3-isopropylmalate dehydratase, large subunit n=1
Tax=Sulfurihydrogenibium azorense Az-Fu1
RepID=C1DUH4_SULAA
Length = 431
Score = 99.8 bits (247), Expect = 1e-19
Identities = 57/139 (41%), Positives = 80/139 (57%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKT 343
ID+V+IGSCT G+ D AA + +V ++PA+ +++ A +
Sbjct: 292 IDQVFIGSCTNGRLSDLRIAAAILKGKKVHPEVRCIVIPASDQIYKQ--------ALHEG 343
Query: 342 CAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYLA 163
+I +AGC S +CG CLGG A E +VC+ST+NRNF GRMGH + Q+YL+
Sbjct: 344 IIEILADAGCLISTS-TCGPCLGGHMGILA---EGEVCLSTSNRNFVGRMGHPKSQVYLS 399
Query: 162 SPYTAAASALTGRVADPRE 106
SP AAASA+ GR+A P E
Sbjct: 400 SPAVAAASAVLGRIAHPDE 418
[192][TOP]
>UniRef100_Q24XT4 3-isopropylmalate dehydratase large subunit n=2
Tax=Desulfitobacterium hafniense RepID=LEUC_DESHY
Length = 421
Score = 99.8 bits (247), Expect = 1e-19
Identities = 57/143 (39%), Positives = 80/143 (55%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KID+V IGSCT G+ ED AA++ V ++P TQ ++ A
Sbjct: 291 IKIDQVVIGSCTNGRLEDMQVAAQILKGQKVHGDVRLIVIPGTQDIYKQ--------AMQ 342
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ IF +AG ++P+CG CLGG A+ + +STTNRNF GRMGH E ++Y
Sbjct: 343 EGLIDIFIDAGA-VVSTPTCGPCLGGYMGILAK---GERALSTTNRNFVGRMGHPESEVY 398
Query: 168 LASPYTAAASALTGRVADPREFL 100
L+ P AAASA+TG ++ P E L
Sbjct: 399 LSGPAVAAASAVTGEISHPEEVL 421
[193][TOP]
>UniRef100_B1I1Y2 3-isopropylmalate dehydratase, large subunit n=1 Tax=Candidatus
Desulforudis audaxviator MP104C RepID=B1I1Y2_DESAP
Length = 420
Score = 99.8 bits (247), Expect = 1e-19
Identities = 58/141 (41%), Positives = 80/141 (56%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
V+ID+V IGSCT G+ ED AA++ V ++P TQ+++ A
Sbjct: 290 VEIDQVVIGSCTNGRMEDLRLAARVLERRRVHAGVRLIVIPGTQEIYRQ--------AME 341
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ IF +AG ++P+CG CLGG AR + V+TTNRNF GRMGH E ++Y
Sbjct: 342 EGLLAIFIQAGAAV-STPTCGPCLGGHMGVLAR---GERAVATTNRNFVGRMGHPESEVY 397
Query: 168 LASPYTAAASALTGRVADPRE 106
L +P AAASA+ GR+A P E
Sbjct: 398 LTNPAVAAASAVLGRIAHPGE 418
[194][TOP]
>UniRef100_A9BGP4 3-isopropylmalate dehydratase, large subunit n=1 Tax=Petrotoga
mobilis SJ95 RepID=A9BGP4_PETMO
Length = 419
Score = 99.8 bits (247), Expect = 1e-19
Identities = 56/144 (38%), Positives = 79/144 (54%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KID+ IGSCT G+ ED AA + V + P TQ ++M
Sbjct: 288 IKIDQSVIGSCTNGRIEDLRIAAHVLKGHKVNSDVRCIIFPGTQDIYMQALK-------- 339
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ +IF EAG ++P+CG CLGG A+ + +STTNRNF GRMGH E ++Y
Sbjct: 340 EGLIEIFIEAGAAV-STPTCGPCLGGHMGVLAK---GEKAISTTNRNFVGRMGHPESEVY 395
Query: 168 LASPYTAAASALTGRVADPREFLQ 97
L++P AAASA+TG + P E ++
Sbjct: 396 LSNPAVAAASAITGYITHPEEVIR 419
[195][TOP]
>UniRef100_A6TSE5 3-isopropylmalate dehydratase n=1 Tax=Alkaliphilus metalliredigens
QYMF RepID=A6TSE5_ALKMQ
Length = 425
Score = 99.8 bits (247), Expect = 1e-19
Identities = 59/146 (40%), Positives = 85/146 (58%), Gaps = 1/146 (0%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
+VK+D+V+IG+CTGG+ ED AA++ ++PA+++V + A
Sbjct: 285 EVKVDQVFIGTCTGGRLEDIEVAARIIKNNKIHRDTRLLVIPASKEV--------LEKAI 336
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEP-QVCVSTTNRNFPGRMGHKEGQ 175
K +AG T SP CG CLG T+ L P +VC +T++RNFPGRMG E
Sbjct: 337 EKGYMTTLIKAGA-TFTSPGCGPCLG----THQGLLAPGEVCATTSSRNFPGRMGSTEAD 391
Query: 174 IYLASPYTAAASALTGRVADPREFLQ 97
IYL SP TAAA A+TG++ DPR +++
Sbjct: 392 IYLVSPATAAAIAITGKITDPRGYIE 417
[196][TOP]
>UniRef100_B5IER5 Homoaconitate hydratase family protein n=1 Tax=Aciduliprofundum
boonei T469 RepID=B5IER5_9EURY
Length = 418
Score = 99.8 bits (247), Expect = 1e-19
Identities = 56/143 (39%), Positives = 79/143 (55%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+++++V++G+CT G+ ED AA++ V + PA+ VW + A
Sbjct: 288 IEVNQVFLGTCTNGRVEDLEIAARILKGKKVNKNVRMLVFPASWDVWRE--------ADE 339
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
K + EAG +P CG CLG A A + + C+ST NRNF GRMG+ +IY
Sbjct: 340 KGILRTLAEAGA-VIMNPGCGPCLGAHAGVLA---DGEKCLSTANRNFKGRMGNPNAEIY 395
Query: 168 LASPYTAAASALTGRVADPREFL 100
L SP TAAA+AL G +ADPRE L
Sbjct: 396 LGSPATAAATALKGYIADPREVL 418
[197][TOP]
>UniRef100_B9L6Y8 3-isopropylmalate dehydratase large subunit n=1 Tax=Nautilia
profundicola AmH RepID=LEUC_NAUPA
Length = 425
Score = 99.8 bits (247), Expect = 1e-19
Identities = 56/142 (39%), Positives = 82/142 (57%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
D++ID+VYIGSCT G D AA++ +V + PATQ+++ A
Sbjct: 295 DIEIDQVYIGSCTNGTLSDLRIAAEILKGKRVHRRVRLIVTPATQRIYKQ--------AE 346
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ I +AG A+P+CGACLGG L + + V+TTNRNF GRMG + ++
Sbjct: 347 HEGILDILIDAGA-VVANPTCGACLGGYMGI---LGDGERAVATTNRNFRGRMGSRSSEV 402
Query: 171 YLASPYTAAASALTGRVADPRE 106
YL++ AAASA+ G++ADPR+
Sbjct: 403 YLSNSAVAAASAIAGKIADPRD 424
[198][TOP]
>UniRef100_B9L0Y1 3-isopropylmalate dehydratase, large subunit n=1
Tax=Thermomicrobium roseum DSM 5159 RepID=B9L0Y1_THERP
Length = 422
Score = 99.4 bits (246), Expect = 1e-19
Identities = 61/142 (42%), Positives = 79/142 (55%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
D+ ID+V IGSCT G+ D AA++ +V ++P +Q+V A
Sbjct: 291 DLPIDQVVIGSCTNGRLSDLRIAAEILKGRQVHPRVRCIVIPGSQEV--------AKQAT 342
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ IF EAG S +CG CLGG A+ + CVSTTNRNF GRMGH+E ++
Sbjct: 343 REGLVDIFLEAGAVFSVS-TCGPCLGGYMGVLAK---GERCVSTTNRNFRGRMGHRESEV 398
Query: 171 YLASPYTAAASALTGRVADPRE 106
LASP AAASA+ GRVA P E
Sbjct: 399 ILASPAVAAASAVLGRVASPFE 420
[199][TOP]
>UniRef100_C4FI11 3-isopropylmalate dehydratase, large subunit n=1
Tax=Sulfurihydrogenibium yellowstonense SS-5
RepID=C4FI11_9AQUI
Length = 431
Score = 99.4 bits (246), Expect = 1e-19
Identities = 57/139 (41%), Positives = 79/139 (56%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKT 343
ID+V+IGSCT G+ D AA + +V ++PA+ +++ A +
Sbjct: 292 IDQVFIGSCTNGRLSDLRIAAAILKGKKVHPEVRCIVIPASDQIYKQ--------ALHEG 343
Query: 342 CAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYLA 163
+I EAGC S +CG CLGG A E +VC+ST+NRNF GRMGH + Q+YL+
Sbjct: 344 IIEILAEAGCLISTS-TCGPCLGGHMGILA---EGEVCLSTSNRNFVGRMGHPKSQVYLS 399
Query: 162 SPYTAAASALTGRVADPRE 106
SP AAASA+ GR+ P E
Sbjct: 400 SPAVAAASAVLGRIVHPDE 418
[200][TOP]
>UniRef100_B9MLV4 3-isopropylmalate dehydratase large subunit n=1 Tax=Anaerocellum
thermophilum DSM 6725 RepID=LEUC_ANATD
Length = 429
Score = 99.4 bits (246), Expect = 1e-19
Identities = 59/143 (41%), Positives = 82/143 (57%), Gaps = 2/143 (1%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPGA 355
+ ID+V IGSCT G+ ED AAK+ GRKVK + + PATQ ++
Sbjct: 293 IYIDQVVIGSCTNGRIEDLRIAAKILK--GRKVKKGLRCIIFPATQNIYKQALK------ 344
Query: 354 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 175
+ +IF +AGC ++P+CG CLGG A + + ++TTNRNF GRMGH +
Sbjct: 345 --EGFIEIFIDAGC-VVSTPTCGPCLGGHMGILA---DGEKALATTNRNFVGRMGHPNSE 398
Query: 174 IYLASPYTAAASALTGRVADPRE 106
+YL+SP AAASA+ G + P E
Sbjct: 399 VYLSSPAIAAASAVLGYIGSPEE 421
[201][TOP]
>UniRef100_B1L9K1 3-isopropylmalate dehydratase n=1 Tax=Thermotoga sp. RQ2
RepID=B1L9K1_THESQ
Length = 418
Score = 99.0 bits (245), Expect = 2e-19
Identities = 57/143 (39%), Positives = 80/143 (55%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KID+V+IG+CT G+ +D A K+ G+ V + PA++KV+MD
Sbjct: 288 IKIDQVFIGTCTNGRLQDLEIALKILEKHGKHPDVRLIVGPASRKVYMDALE-------- 339
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
K + F E G P CG C+G L + + +ST NRNF GRMG+ +IY
Sbjct: 340 KGIIKKFVELGAAV-IPPGCGPCVGIHMGV---LGDGERVLSTQNRNFKGRMGNPNAEIY 395
Query: 168 LASPYTAAASALTGRVADPREFL 100
LASP TAAA+A+TG + DPR F+
Sbjct: 396 LASPATAAATAVTGYITDPRRFI 418
[202][TOP]
>UniRef100_C7IAQ1 3-isopropylmalate dehydratase n=1 Tax=Thermotoga naphthophila
RKU-10 RepID=C7IAQ1_9THEM
Length = 418
Score = 99.0 bits (245), Expect = 2e-19
Identities = 57/143 (39%), Positives = 80/143 (55%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KID+V+IG+CT G+ +D A K+ G+ V + PA++KV+MD
Sbjct: 288 IKIDQVFIGTCTNGRLQDLEIALKILEKHGKHPDVRLIVGPASRKVYMDALE-------- 339
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
K + F E G P CG C+G L + + +ST NRNF GRMG+ +IY
Sbjct: 340 KGIIKKFVELGAAV-IPPGCGPCVGIHMGV---LGDGERVLSTQNRNFKGRMGNPNAEIY 395
Query: 168 LASPYTAAASALTGRVADPREFL 100
LASP TAAA+A+TG + DPR F+
Sbjct: 396 LASPATAAATAVTGYITDPRRFI 418
[203][TOP]
>UniRef100_A5IKB8 3-isopropylmalate dehydratase, large subunit n=2 Tax=Thermotogaceae
RepID=A5IKB8_THEP1
Length = 418
Score = 99.0 bits (245), Expect = 2e-19
Identities = 57/143 (39%), Positives = 80/143 (55%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KID+V+IG+CT G+ +D A K+ G+ V + PA++KV+MD
Sbjct: 288 IKIDQVFIGTCTNGRLQDLEIALKILEKHGKHPDVRLIVGPASRKVYMDALE-------- 339
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
K + F E G P CG C+G L + + +ST NRNF GRMG+ +IY
Sbjct: 340 KGIIKKFVELGAAV-IPPGCGPCVGIHMGV---LGDGERVLSTQNRNFKGRMGNPNAEIY 395
Query: 168 LASPYTAAASALTGRVADPREFL 100
LASP TAAA+A+TG + DPR F+
Sbjct: 396 LASPATAAATAVTGYITDPRRFI 418
[204][TOP]
>UniRef100_B1H0A6 3-isopropylmalate dehydratase large subunit n=1 Tax=uncultured
Termite group 1 bacterium phylotype Rs-D17
RepID=LEUC_UNCTG
Length = 420
Score = 99.0 bits (245), Expect = 2e-19
Identities = 62/141 (43%), Positives = 80/141 (56%), Gaps = 2/141 (1%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPGAGG 349
ID+V IGSCT G+ ED AA + G+KV V T ++PAT +V+ A
Sbjct: 292 IDQVVIGSCTNGRIEDLRVAASIIKK-GKKVNSNVRTLIIPATPEVYSQ--------ALD 342
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ +IF +AG A P+CG CLGG A + C STTNRNF GRMGH E Q++
Sbjct: 343 EGLLRIFMDAGAIISA-PTCGPCLGGHMGILA---SGEKCASTTNRNFRGRMGHVESQLF 398
Query: 168 LASPYTAAASALTGRVADPRE 106
L +P AAASA+ G +A P E
Sbjct: 399 LVNPAVAAASAIKGYIASPDE 419
[205][TOP]
>UniRef100_A1RVH3 3-isopropylmalate dehydratase large subunit n=1 Tax=Pyrobaculum
islandicum DSM 4184 RepID=LEUC_PYRIL
Length = 414
Score = 99.0 bits (245), Expect = 2e-19
Identities = 56/143 (39%), Positives = 81/143 (56%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
V++D+V+IGSCT G+ DF AA++ +VK +PA+ ++ L
Sbjct: 285 VEVDQVFIGSCTNGRLSDFEIAARILRRG--RVKSRCIAIPASYTIFRKALELGY----- 337
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
I +AGC +CG CLGG + +V VST+NRNF GRMGH + ++Y
Sbjct: 338 ---IDILTKAGCVVTYG-TCGPCLGGH---FGVAGPGEVVVSTSNRNFKGRMGHPDSKVY 390
Query: 168 LASPYTAAASALTGRVADPREFL 100
LA+P TAAA+AL G++ DPR +L
Sbjct: 391 LANPATAAAAALEGKIVDPRPYL 413
[206][TOP]
>UniRef100_B2KBD7 3-isopropylmalate dehydratase large subunit n=1 Tax=Elusimicrobium
minutum Pei191 RepID=LEUC_ELUMP
Length = 418
Score = 99.0 bits (245), Expect = 2e-19
Identities = 56/145 (38%), Positives = 84/145 (57%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
D+K+++V+IG+CT G+ ED AA++ TF+ PA++ V + A
Sbjct: 286 DIKVNQVFIGTCTNGRIEDLRIAAEILKDKKVNPGTRTFITPASRDVML--------AAL 337
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ +IF +AG +P CG C+G L + +VC++T NRNF GRMG+ +G I
Sbjct: 338 KEGLIEIFVKAGASVQ-TPGCGPCVGVHGGI---LGDGEVCLATQNRNFQGRMGNTKGFI 393
Query: 171 YLASPYTAAASALTGRVADPREFLQ 97
YL+SP AA SAL G ++DPRE L+
Sbjct: 394 YLSSPAVAAYSALKGYISDPREILK 418
[207][TOP]
>UniRef100_Q9WYC7 3-isopropylmalate dehydratase large subunit 1 n=1 Tax=Thermotoga
maritima RepID=LEUC1_THEMA
Length = 418
Score = 99.0 bits (245), Expect = 2e-19
Identities = 57/143 (39%), Positives = 80/143 (55%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KID+V+IG+CT G+ +D A K+ G+ V + PA++KV+MD
Sbjct: 288 IKIDQVFIGTCTNGRLQDLEIALKILEKHGKHPDVRLIVGPASRKVYMDALE-------- 339
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
K + F E G P CG C+G L + + +ST NRNF GRMG+ +IY
Sbjct: 340 KGIIKKFVELGAAV-IPPGCGPCVGIHMGV---LGDGERVLSTQNRNFKGRMGNPNAEIY 395
Query: 168 LASPYTAAASALTGRVADPREFL 100
LASP TAAA+A+TG + DPR F+
Sbjct: 396 LASPATAAATAVTGYITDPRRFI 418
[208][TOP]
>UniRef100_Q1Q122 Similar to 3-isopropylmalate dehydratase, large subunit n=1
Tax=Candidatus Kuenenia stuttgartiensis
RepID=Q1Q122_9BACT
Length = 437
Score = 98.6 bits (244), Expect = 2e-19
Identities = 55/141 (39%), Positives = 79/141 (56%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KID+V IGSCT G+ D AAK+ + ++PATQ+++
Sbjct: 297 IKIDQVVIGSCTNGRISDLRIAAKILKGKKAHPSLRLIIIPATQEIYKQALK-------- 348
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ +IF +A ++P+CG CLGG A E + ++TTNRNF GRMGH + +IY
Sbjct: 349 EGLIEIFIDAEA-VVSTPTCGPCLGGHMGILA---EGERALTTTNRNFVGRMGHPKSEIY 404
Query: 168 LASPYTAAASALTGRVADPRE 106
L SP AAASA+TG++ P E
Sbjct: 405 LCSPAVAAASAITGKITPPSE 425
[209][TOP]
>UniRef100_Q1NU24 Cis-homoaconitase:3-isopropylmalate dehydratase, prokaryotic n=1
Tax=delta proteobacterium MLMS-1 RepID=Q1NU24_9DELT
Length = 428
Score = 98.6 bits (244), Expect = 2e-19
Identities = 65/144 (45%), Positives = 85/144 (59%), Gaps = 3/144 (2%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKV--KVPTFLVPATQKVWMDVYALPVPGAGG 349
+D++YIGSCT G+ ED AA++ GRK+ +V L PAT KV A
Sbjct: 300 VDQIYIGSCTNGRIEDLREAARIL--KGRKISEQVRGILAPATPKV--------AAQALE 349
Query: 348 KTCAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ +IF EAG C T +P+CGACLG A E ++C STTNRNF GRMG K G +
Sbjct: 350 EGILKIFMEAGFCVT--NPTCGACLGMSNGVLA---EGEICASTTNRNFNGRMG-KGGIV 403
Query: 171 YLASPYTAAASALTGRVADPREFL 100
+L SP +AAA+A+ G + DPR L
Sbjct: 404 HLMSPLSAAAAAVAGHITDPRPLL 427
[210][TOP]
>UniRef100_Q1NII2 Cis-homoaconitase:3-isopropylmalate dehydratase, prokaryotic n=1
Tax=delta proteobacterium MLMS-1 RepID=Q1NII2_9DELT
Length = 428
Score = 98.6 bits (244), Expect = 2e-19
Identities = 65/144 (45%), Positives = 85/144 (59%), Gaps = 3/144 (2%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKV--KVPTFLVPATQKVWMDVYALPVPGAGG 349
+D++YIGSCT G+ ED AA++ GRK+ +V L PAT KV A
Sbjct: 300 VDQIYIGSCTNGRIEDLREAARIL--KGRKISEQVRGILAPATPKV--------AAQALE 349
Query: 348 KTCAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ +IF EAG C T +P+CGACLG A E ++C STTNRNF GRMG K G +
Sbjct: 350 EGILKIFMEAGFCVT--NPTCGACLGMSNGVLA---EGEICASTTNRNFNGRMG-KGGIV 403
Query: 171 YLASPYTAAASALTGRVADPREFL 100
+L SP +AAA+A+ G + DPR L
Sbjct: 404 HLMSPLSAAAAAVAGHITDPRPLL 427
[211][TOP]
>UniRef100_A8ABG2 3-isopropylmalate dehydratase n=1 Tax=Ignicoccus hospitalis KIN4/I
RepID=A8ABG2_IGNH4
Length = 429
Score = 98.6 bits (244), Expect = 2e-19
Identities = 57/146 (39%), Positives = 86/146 (58%), Gaps = 2/146 (1%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPT--FLVPATQKVWMDVYALPVPGA 355
+++D+V+IGSCT G+ ED AA++ G+KV T ++ A++ V++
Sbjct: 290 IEVDQVFIGSCTNGRLEDVAVAARILK--GKKVAPNTRCIVITASRNVYLQALK------ 341
Query: 354 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 175
K + EAGC +CG C+G Y L +V + TTNRNF GR GH+ +
Sbjct: 342 --KGYVDVLTEAGCLVTFG-TCGPCVGAH---YGVLGPNEVGLFTTNRNFRGRSGHRTSK 395
Query: 174 IYLASPYTAAASALTGRVADPREFLQ 97
+YLASP TAAASA+ G++ADPR++L+
Sbjct: 396 VYLASPATAAASAVEGKIADPRKYLK 421
[212][TOP]
>UniRef100_B0TCR2 3-isopropylmalate dehydratase large subunit n=1 Tax=Heliobacterium
modesticaldum Ice1 RepID=LEUC_HELMI
Length = 420
Score = 98.6 bits (244), Expect = 2e-19
Identities = 56/141 (39%), Positives = 76/141 (53%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
V+ID+V IGSCT G+ ED AAK+ V + P TQ ++
Sbjct: 290 VEIDQVVIGSCTNGRIEDLRMAAKILQGKKVHKNVRCIIFPGTQAIYKQAIK-------- 341
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ IF +AG ++P+CG CLGG A+ + ++TTNRNF GRMGH E ++Y
Sbjct: 342 EGLIDIFIDAGAAV-STPTCGPCLGGHMGILAK---GERALATTNRNFVGRMGHPESEVY 397
Query: 168 LASPYTAAASALTGRVADPRE 106
L P AAASA+ GR+ PRE
Sbjct: 398 LCGPNVAAASAIAGRIVHPRE 418
[213][TOP]
>UniRef100_C0QS35 3-isopropylmalate dehydratase, large subunit n=1 Tax=Persephonella
marina EX-H1 RepID=C0QS35_PERMH
Length = 428
Score = 98.2 bits (243), Expect = 3e-19
Identities = 60/141 (42%), Positives = 81/141 (57%), Gaps = 2/141 (1%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPGAGG 349
I++V+IGSCT G+ D AA + GRKV V ++PA+ +++ A
Sbjct: 292 INQVFIGSCTNGRMSDLRIAAHILK--GRKVHPDVRCIVIPASDRIYKQ--------ALH 341
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ +I +AGC S +CG CLGG A E +VCVST+NRNF GRMGH ++Y
Sbjct: 342 EGILEILADAGCLISTS-TCGPCLGGHMGILA---EGEVCVSTSNRNFTGRMGHPNSEVY 397
Query: 168 LASPYTAAASALTGRVADPRE 106
LA P AAASA+ GR+A P E
Sbjct: 398 LAGPAVAAASAVLGRIAHPDE 418
[214][TOP]
>UniRef100_C9KJM7 3-isopropylmalate dehydratase, large subunit n=2 Tax=Mitsuokella
multacida DSM 20544 RepID=C9KJM7_9FIRM
Length = 420
Score = 98.2 bits (243), Expect = 3e-19
Identities = 55/141 (39%), Positives = 78/141 (55%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
++ID+V IGSCT G+ ED AA + +V ++P + ++ +
Sbjct: 290 IEIDQVIIGSCTNGRLEDMEIAASILKGHKVADRVRCIVIPGSPAIYKESMK-------- 341
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ F +AGC ++P+CG CLGG A + CVSTTNRNF GRMGH + ++Y
Sbjct: 342 RGYIDTFIDAGCAV-STPTCGPCLGGYMGIMAA---GERCVSTTNRNFRGRMGHVDSEVY 397
Query: 168 LASPYTAAASALTGRVADPRE 106
LA P AAASA+ GR+A P E
Sbjct: 398 LAGPQVAAASAILGRIATPEE 418
[215][TOP]
>UniRef100_B1L5I9 3-isopropylmalate dehydratase n=1 Tax=Candidatus Korarchaeum
cryptofilum OPF8 RepID=B1L5I9_KORCO
Length = 413
Score = 98.2 bits (243), Expect = 3e-19
Identities = 58/148 (39%), Positives = 82/148 (55%), Gaps = 6/148 (4%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
++D V+IGSC+GG+ EDF+ A+++ K V VPA+++V M +
Sbjct: 283 EVDLVFIGSCSGGRFEDFLLASRIMRGRKLKEGVRCITVPASKEVQMKLI--------DS 334
Query: 345 TCAQIFEEAGCDTPASPSCGACLG------GPADTYARLNEPQVCVSTTNRNFPGRMGHK 184
+ E GC T P+CG C+G GP +T VST+ RNFPGRMG
Sbjct: 335 GLMRSLLEFGC-TVGPPTCGPCIGAHMGLAGPGETV---------VSTSTRNFPGRMGSP 384
Query: 183 EGQIYLASPYTAAASALTGRVADPREFL 100
+ ++YLASP TAAASA+ G++ DP FL
Sbjct: 385 DSRVYLASPLTAAASAVEGKLTDPGRFL 412
[216][TOP]
>UniRef100_B8J825 3-isopropylmalate dehydratase large subunit n=1
Tax=Anaeromyxobacter dehalogenans 2CP-1 RepID=LEUC_ANAD2
Length = 480
Score = 98.2 bits (243), Expect = 3e-19
Identities = 62/143 (43%), Positives = 80/143 (55%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
K+D V+IGSCT G+ ED AA++ GRKV+ T +VP + +V D A +
Sbjct: 351 KVDVVFIGSCTNGRIEDMREAARVLK--GRKVRTRTLVVPGSHRVKKDAEAEGID----- 403
Query: 345 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
+I EAG + P C C+ D L Q CVST+NRNF GR G G+ L
Sbjct: 404 ---RIVREAGAEW-REPGCSMCIAMNGDN---LQAGQYCVSTSNRNFEGRQG-PGGRTLL 455
Query: 165 ASPYTAAASALTGRVADPREFLQ 97
ASP TAAA+A+TG VADPR L+
Sbjct: 456 ASPLTAAAAAVTGAVADPRRVLE 478
[217][TOP]
>UniRef100_Q1K341 Homoaconitate hydratase family protein n=1 Tax=Desulfuromonas
acetoxidans DSM 684 RepID=Q1K341_DESAC
Length = 427
Score = 97.8 bits (242), Expect = 4e-19
Identities = 60/139 (43%), Positives = 81/139 (58%), Gaps = 1/139 (0%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKT 343
+D++YIG+CT G+ ED AA + V + PAT K++ D A +
Sbjct: 300 VDQIYIGTCTNGRIEDLREAAAILKGRRIADTVRGIVSPATPKIFRDALA--------EG 351
Query: 342 CAQIFEEAG-CDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
QIF +AG C T +P+CGACLG A E +VC ST+NRNF GRMG K G ++L
Sbjct: 352 IIQIFMDAGFCVT--NPTCGACLGMSNGVLA---EGEVCASTSNRNFNGRMG-KGGMVHL 405
Query: 165 ASPYTAAASALTGRVADPR 109
SP TAAA+A+TG++ D R
Sbjct: 406 MSPATAAATAITGKITDAR 424
[218][TOP]
>UniRef100_C9RD99 3-isopropylmalate dehydratase n=1 Tax=Ammonifex degensii KC4
RepID=C9RD99_9THEO
Length = 418
Score = 97.8 bits (242), Expect = 4e-19
Identities = 60/145 (41%), Positives = 84/145 (57%), Gaps = 2/145 (1%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKV--KVPTFLVPATQKVWMDVYALPVPGAG 352
KID+ +IG+CT G+ ED AA++ AGRK+ +V + PA++KV++ A
Sbjct: 288 KIDQAFIGTCTNGRLEDLRVAARIL--AGRKIHPRVRLVVAPASRKVYLQ--------AM 337
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ EAG +P CG C+G A + +V VST NRNF GRMG+ + +I
Sbjct: 338 REGILATLVEAGAAV-VTPGCGPCVGTHNGVPA---DGEVVVSTANRNFKGRMGNAKAEI 393
Query: 171 YLASPYTAAASALTGRVADPREFLQ 97
YLASP T AASA+ G + DPR FL+
Sbjct: 394 YLASPATVAASAIAGEITDPRLFLK 418
[219][TOP]
>UniRef100_C1I927 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium sp.
7_2_43FAA RepID=C1I927_9CLOT
Length = 424
Score = 97.8 bits (242), Expect = 4e-19
Identities = 56/142 (39%), Positives = 78/142 (54%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
+V +D+V IGSCT G+ D A + K V + P TQK+++ +
Sbjct: 289 EVAVDQVVIGSCTNGRISDLRVARDILKNKKVKKGVRCIVFPGTQKIYLQALEEGI---- 344
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ EAG ++P+CG CLGG A+ + +STTNRNF GRMGH E ++
Sbjct: 345 ----IKDLVEAGA-VVSTPTCGPCLGGHMGILAK---GERAISTTNRNFVGRMGHVESEV 396
Query: 171 YLASPYTAAASALTGRVADPRE 106
YLASP AAASALTG++ +P E
Sbjct: 397 YLASPAVAAASALTGKITNPEE 418
[220][TOP]
>UniRef100_Q3AEQ4 3-isopropylmalate dehydratase, large subunit n=1
Tax=Carboxydothermus hydrogenoformans Z-2901
RepID=Q3AEQ4_CARHZ
Length = 421
Score = 97.4 bits (241), Expect = 5e-19
Identities = 59/141 (41%), Positives = 79/141 (56%), Gaps = 2/141 (1%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPGAGG 349
ID+V IGSCT G+ ED AA + G+KVK V ++P +Q V+
Sbjct: 293 IDQVVIGSCTNGRIEDLRVAAAILK--GKKVKDYVRCIIIPGSQSVYRQALK-------- 342
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ IF EAG ++P+CG CLGG A+ + V+TTNRNF GRMGH E ++Y
Sbjct: 343 EGLIDIFLEAGAAV-STPTCGPCLGGHMGILAK---GERAVATTNRNFVGRMGHVESEVY 398
Query: 168 LASPYTAAASALTGRVADPRE 106
LA P AAASA+ G++ P E
Sbjct: 399 LAGPAVAAASAIAGKIVHPEE 419
[221][TOP]
>UniRef100_C5EHB8 3-isopropylmalate dehydratase n=1 Tax=Clostridiales bacterium
1_7_47FAA RepID=C5EHB8_9FIRM
Length = 438
Score = 97.4 bits (241), Expect = 5e-19
Identities = 65/142 (45%), Positives = 80/142 (56%), Gaps = 2/142 (1%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPGAG 352
KID VYIGSCT G ED AA++ G+KV + +VPAT KV+ D A AG
Sbjct: 297 KIDEVYIGSCTNGSLEDMRIAAEIME--GKKVPDDLRVIVVPATNKVFKDAIA-----AG 349
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ F EAGC + P CG C G P Y + + + +ST NRNF GR G K+
Sbjct: 350 ---YIRTFIEAGC-VISHPCCGLCCGMP---YGLMYDDERILSTANRNFIGRQGTKKTLS 402
Query: 171 YLASPYTAAASALTGRVADPRE 106
YL+SP AAA+AL G V DPRE
Sbjct: 403 YLSSPAVAAATALAGVVTDPRE 424
[222][TOP]
>UniRef100_C4V4K3 3-isopropylmalate dehydratase n=1 Tax=Selenomonas flueggei ATCC
43531 RepID=C4V4K3_9FIRM
Length = 420
Score = 97.4 bits (241), Expect = 5e-19
Identities = 57/141 (40%), Positives = 78/141 (55%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+ ID+V IGSCT G+ ED AA + +V ++P + V+ +
Sbjct: 290 IAIDQVVIGSCTNGRLEDMEIAASILKGHKVHERVRCIVIPGSPYVYEESMK-------- 341
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ IF EAG ++P+CG CLGG A + CVSTTNRNF GRMGH + ++Y
Sbjct: 342 RGYLAIFMEAGAAI-STPTCGPCLGGYMGILAA---GERCVSTTNRNFRGRMGHVDSEVY 397
Query: 168 LASPYTAAASALTGRVADPRE 106
LA P+ AAASA+ GR+A P E
Sbjct: 398 LAGPHVAAASAILGRIAAPEE 418
[223][TOP]
>UniRef100_B6BGP4 3-isopropylmalate dehydratase large subunit n=1
Tax=Campylobacterales bacterium GD 1 RepID=B6BGP4_9PROT
Length = 419
Score = 97.4 bits (241), Expect = 5e-19
Identities = 56/140 (40%), Positives = 77/140 (55%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KID+ +IGSCT G+ D AA++ V + P TQK+ + Y L
Sbjct: 292 IKIDQAFIGSCTNGRLGDLKTAAEILDGKKVHEDVRLIVTPGTQKILKEAYRLGY----- 346
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
I +AG ++P+CGACLGG L + +V VSTTNRNF GRMG + ++Y
Sbjct: 347 ---MDIIIDAG-GVVSNPTCGACLGGYMGI---LGDNEVAVSTTNRNFVGRMGSRSSKVY 399
Query: 168 LASPYTAAASALTGRVADPR 109
LA+ AA SA+TG + DPR
Sbjct: 400 LANSAVAAISAITGYITDPR 419
[224][TOP]
>UniRef100_C8SB74 Homoaconitate hydratase family protein n=1 Tax=Ferroglobus placidus
DSM 10642 RepID=C8SB74_FERPL
Length = 419
Score = 97.4 bits (241), Expect = 5e-19
Identities = 57/141 (40%), Positives = 79/141 (56%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
VKID+V+IGSCT G+ ED AA++ V ++PA++ +
Sbjct: 290 VKIDQVFIGSCTNGRYEDLKVAAEILKGEKVAKGVRLIVIPASRSHYKRALK-------- 341
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ IF EAG PSCG C+GG ++ + +V +ST+NRNF GR G EG+IY
Sbjct: 342 EGLIDIFVEAGAIVEF-PSCGPCMGG---SFGLIASKEVSLSTSNRNFIGRQGSPEGEIY 397
Query: 168 LASPYTAAASALTGRVADPRE 106
L SP TAAASA+ G + DPR+
Sbjct: 398 LCSPATAAASAIYGEITDPRK 418
[225][TOP]
>UniRef100_B4UAN0 3-isopropylmalate dehydratase large subunit n=1
Tax=Anaeromyxobacter sp. K RepID=LEUC_ANASK
Length = 480
Score = 97.4 bits (241), Expect = 5e-19
Identities = 61/143 (42%), Positives = 80/143 (55%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
K+D V+IGSCT G+ ED AA++ GRKV+ T +VP + +V D A +
Sbjct: 351 KVDVVFIGSCTNGRIEDMREAARVLK--GRKVRTRTLVVPGSHRVKKDAEAEGID----- 403
Query: 345 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
+I EAG + P C C+ D + Q CVST+NRNF GR G G+ L
Sbjct: 404 ---RIVREAGAEW-REPGCSMCIAMNGDN---IQAGQYCVSTSNRNFEGRQG-PGGRTLL 455
Query: 165 ASPYTAAASALTGRVADPREFLQ 97
ASP TAAA+A+TG VADPR L+
Sbjct: 456 ASPLTAAAAAVTGAVADPRRVLE 478
[226][TOP]
>UniRef100_B9KC23 3-isopropylmalate dehydratase large subunit 1 n=1 Tax=Thermotoga
neapolitana DSM 4359 RepID=B9KC23_THENN
Length = 420
Score = 97.1 bits (240), Expect = 7e-19
Identities = 56/143 (39%), Positives = 80/143 (55%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+KID+V+IG+CT G+ +D A ++ G+ V + PA++KV+MD
Sbjct: 290 IKIDQVFIGTCTNGRLQDLEIALRILEKHGKHPDVRLIVGPASRKVYMDALE-------- 341
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
K + F E G P CG C+G L + + +ST NRNF GRMG+ +IY
Sbjct: 342 KGIIKRFVELGAAI-IPPGCGPCVGIHMGV---LGDGERVLSTQNRNFKGRMGNPNAEIY 397
Query: 168 LASPYTAAASALTGRVADPREFL 100
LASP TAAA+A+ G +ADPR F+
Sbjct: 398 LASPATAAATAVAGYIADPRRFI 420
[227][TOP]
>UniRef100_C3XG48 3-isopropylmalate dehydratase large subunit n=1 Tax=Helicobacter
bilis ATCC 43879 RepID=C3XG48_9HELI
Length = 420
Score = 97.1 bits (240), Expect = 7e-19
Identities = 55/144 (38%), Positives = 81/144 (56%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
++KID+V IGSCT G+ D AA + ++PATQ ++++
Sbjct: 289 EIKIDQVVIGSCTNGRLSDMEVAANILKDKTIAKNTRCIIIPATQNIYLECI-------- 340
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ + F +AG ++P+CG CLGG A NE CVSTTNRNF GRMGH ++
Sbjct: 341 NRGYLETFIKAGA-VVSTPTCGPCLGGHMGILAA-NEK--CVSTTNRNFVGRMGHTTSEV 396
Query: 171 YLASPYTAAASALTGRVADPREFL 100
YL+SP AAASA+ G ++ P++ +
Sbjct: 397 YLSSPEVAAASAVRGILSSPQDII 420
[228][TOP]
>UniRef100_A3MWJ4 3-isopropylmalate dehydratase large subunit n=1 Tax=Pyrobaculum
calidifontis JCM 11548 RepID=LEUC_PYRCJ
Length = 413
Score = 97.1 bits (240), Expect = 7e-19
Identities = 53/143 (37%), Positives = 81/143 (56%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+++D+V+IGSCT G+ D AAK+ +VK +PA+ V+ L
Sbjct: 285 IEVDQVFIGSCTNGRLSDIEVAAKILRHG--RVKARCIAIPASYDVFRRAMELGY----- 337
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ +AGC +CG CLGG + +V ++T+NRNF GR+GH + ++Y
Sbjct: 338 ---VDVLTKAGCVVTYG-TCGPCLGGH---FGVAGPGEVVLTTSNRNFKGRVGHPDSKVY 390
Query: 168 LASPYTAAASALTGRVADPREFL 100
LA+P AAA+ALTGR+ DPR++L
Sbjct: 391 LANPAVAAATALTGRITDPRQYL 413
[229][TOP]
>UniRef100_UPI0001979722 3-isopropylmalate dehydratase large subunit n=1 Tax=Helicobacter
cinaedi CCUG 18818 RepID=UPI0001979722
Length = 420
Score = 96.7 bits (239), Expect = 9e-19
Identities = 55/144 (38%), Positives = 81/144 (56%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
++KID+V IGSCT G+ D AA + ++PATQ ++++
Sbjct: 289 EIKIDQVVIGSCTNGRLSDMEVAANILKDKTIAKNTRCIIIPATQNIYLECI-------- 340
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ + F +AG ++P+CG CLGG A NE CVSTTNRNF GRMGH ++
Sbjct: 341 NRGYLETFIKAGA-VVSTPTCGPCLGGHMGILAA-NEK--CVSTTNRNFVGRMGHTTSEV 396
Query: 171 YLASPYTAAASALTGRVADPREFL 100
YL+SP AAASA+ G ++ P++ +
Sbjct: 397 YLSSPEVAAASAVRGILSSPQDVM 420
[230][TOP]
>UniRef100_B0PCM1 Putative uncharacterized protein n=1 Tax=Anaerotruncus colihominis
DSM 17241 RepID=B0PCM1_9FIRM
Length = 396
Score = 96.7 bits (239), Expect = 9e-19
Identities = 58/140 (41%), Positives = 76/140 (54%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
VK+ +V +GSCT G+ D AK F V T +VPA++ V ++ A
Sbjct: 266 VKVTQVVVGSCTNGRINDMEQVAKAFEGKHVHPDVNTLIVPASRDVLEEMEA-------- 317
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ +I +AG T +P CG C G +E V VSTTNRNFPGRMG + IY
Sbjct: 318 RGWCKIIRDAGA-TVLNPGCGPCFGAHEGL---TSERDVVVSTTNRNFPGRMGSMKANIY 373
Query: 168 LASPYTAAASALTGRVADPR 109
LASP TAAA+AL GR+ P+
Sbjct: 374 LASPATAAATALAGRITVPK 393
[231][TOP]
>UniRef100_Q2IJC2 3-isopropylmalate dehydratase large subunit n=1
Tax=Anaeromyxobacter dehalogenans 2CP-C RepID=LEUC_ANADE
Length = 480
Score = 96.7 bits (239), Expect = 9e-19
Identities = 60/143 (41%), Positives = 80/143 (55%)
Frame = -3
Query: 525 KIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGK 346
K+D V+IGSCT G+ ED AA++ GRKV+ T +VP + +V D A +
Sbjct: 351 KVDVVFIGSCTNGRIEDMREAARVLK--GRKVRTRTLVVPGSHRVKKDAEAEGID----- 403
Query: 345 TCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYL 166
++ EAG + P C C+ D + Q CVST+NRNF GR G G+ L
Sbjct: 404 ---RVVREAGAEW-REPGCSMCIAMNGDD---IRAGQYCVSTSNRNFEGRQG-PGGRTLL 455
Query: 165 ASPYTAAASALTGRVADPREFLQ 97
ASP TAAA+A+TG VADPR L+
Sbjct: 456 ASPLTAAAAAVTGAVADPRRVLE 478
[232][TOP]
>UniRef100_A2SR25 3-isopropylmalate dehydratase, large subunit n=1
Tax=Methanocorpusculum labreanum Z RepID=A2SR25_METLZ
Length = 392
Score = 96.3 bits (238), Expect = 1e-18
Identities = 58/139 (41%), Positives = 79/139 (56%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKT 343
+D+V+IGSCT G+ EDF AA++ V +VPA++ +M V +
Sbjct: 265 VDQVFIGSCTNGRYEDFAEAAEVLGDNVFSEDVRVIMVPASKAEYMKVLKAGL------- 317
Query: 342 CAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYLA 163
+ F EAG A P CG C+GG + L +V +ST+NRNF GR G E +YL+
Sbjct: 318 -IEKFVEAGALVEA-PCCGPCMGG---AFGLLAPGEVSLSTSNRNFRGRQGSTESFVYLS 372
Query: 162 SPYTAAASALTGRVADPRE 106
SP TAAASA+TG + DPRE
Sbjct: 373 SPATAAASAITGVITDPRE 391
[233][TOP]
>UniRef100_A0B7V1 3-isopropylmalate dehydratase, large subunit n=1 Tax=Methanosaeta
thermophila PT RepID=A0B7V1_METTP
Length = 423
Score = 96.3 bits (238), Expect = 1e-18
Identities = 54/141 (38%), Positives = 80/141 (56%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
VKID++++GSCT G+ ED AA++ V ++PA++K +M +
Sbjct: 294 VKIDQIFLGSCTNGRFEDLKLAAEVMGDEPVARGVRMIVIPASRKEYMRALRAGL----- 348
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ F EAG SP CG C+GG ++ + +V +ST+NRNF GR G +G++Y
Sbjct: 349 ---IEKFMEAGAIVE-SPCCGPCMGG---SFGLIGPGEVSLSTSNRNFVGRQGSPKGEVY 401
Query: 168 LASPYTAAASALTGRVADPRE 106
L SP A ASA+TG + DPRE
Sbjct: 402 LCSPAVAGASAITGEITDPRE 422
[234][TOP]
>UniRef100_B5IBY4 Homoaconitate hydratase family protein n=1 Tax=Aciduliprofundum
boonei T469 RepID=B5IBY4_9EURY
Length = 409
Score = 96.3 bits (238), Expect = 1e-18
Identities = 57/140 (40%), Positives = 83/140 (59%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
++ID +IGSCT G+ ED +AAAK+ G+K+KVP + P T+++W+ +
Sbjct: 286 MEIDGAFIGSCTNGRYEDLVAAAKIL--KGKKLKVPLTITPTTREIWLRLMK-------- 335
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ +IF EAG +P CG C A+ L +V +STTNRN+PG+ G G++Y
Sbjct: 336 EGIWEIFAEAGA-VLTNPGCGGC----AEGMPGLIGDEVYLSTTNRNYPGKQG--PGKLY 388
Query: 168 LASPYTAAASALTGRVADPR 109
L SP AAASA+ G+V PR
Sbjct: 389 LVSPVIAAASAVEGKVTVPR 408
[235][TOP]
>UniRef100_B5I9M1 Homoaconitate hydratase family protein n=1 Tax=Aciduliprofundum
boonei T469 RepID=B5I9M1_9EURY
Length = 409
Score = 96.3 bits (238), Expect = 1e-18
Identities = 57/140 (40%), Positives = 83/140 (59%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
++ID +IGSCT G+ ED +AAAK+ G+K+KVP + P T+++W+ +
Sbjct: 286 MEIDGAFIGSCTNGRYEDLVAAAKIL--KGKKLKVPLTITPTTREIWLRLMK-------- 335
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ +IF EAG +P CG C A+ L +V +STTNRN+PG+ G G++Y
Sbjct: 336 EGIWEIFAEAGA-VLTNPGCGGC----AEGMPGLIGDEVYLSTTNRNYPGKQG--PGKLY 388
Query: 168 LASPYTAAASALTGRVADPR 109
L SP AAASA+ G+V PR
Sbjct: 389 LVSPVIAAASAVEGKVTVPR 408
[236][TOP]
>UniRef100_Q0AV21 3-isopropylmalate dehydratase, large subunit n=1 Tax=Syntrophomonas
wolfei subsp. wolfei str. Goettingen RepID=Q0AV21_SYNWW
Length = 419
Score = 95.9 bits (237), Expect = 2e-18
Identities = 54/141 (38%), Positives = 78/141 (55%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
V +D+V IGSCT G+ ED A L ++ + P T++++++
Sbjct: 290 VSLDQVVIGSCTNGRIEDMEITASLLKGQKVHPEIRVIIFPGTREIYLEALR-------- 341
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ + F EAG ++P+CG CLGG AR + ++TTNRNF GRMGH E ++Y
Sbjct: 342 RGYIETFIEAGA-VVSTPTCGPCLGGHMGILAR---GEKALATTNRNFVGRMGHPESEVY 397
Query: 168 LASPYTAAASALTGRVADPRE 106
LASP AAASA+ GR+ P E
Sbjct: 398 LASPAVAAASAVKGRITAPWE 418
[237][TOP]
>UniRef100_C4CHB6 3-isopropylmalate dehydratase, large subunit n=1 Tax=Sphaerobacter
thermophilus DSM 20745 RepID=C4CHB6_9CHLR
Length = 418
Score = 95.9 bits (237), Expect = 2e-18
Identities = 60/140 (42%), Positives = 75/140 (53%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
D+ I +V IGSCT G+ D AK+ V ++P +Q+V A
Sbjct: 287 DMPIHQVVIGSCTNGRISDLREVAKILKGRQVHPNVRCIVIPGSQEV--------AKQAT 338
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ A IF EAG S +CG CLGG A+ + CVSTTNRNF GRMGH+E +I
Sbjct: 339 REGLADIFLEAGAIFSTS-TCGPCLGGYMGVLAK---GERCVSTTNRNFRGRMGHREAEI 394
Query: 171 YLASPYTAAASALTGRVADP 112
LA P AAASA+ GRVA P
Sbjct: 395 ILAGPQVAAASAVLGRVASP 414
[238][TOP]
>UniRef100_C2KW91 3-isopropylmalate dehydratase n=1 Tax=Oribacterium sinus F0268
RepID=C2KW91_9FIRM
Length = 421
Score = 95.9 bits (237), Expect = 2e-18
Identities = 60/144 (41%), Positives = 83/144 (57%), Gaps = 3/144 (2%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKV--KVPTFLVPATQKVWMDVYALPVPGA 355
+ ID+ IGSCT G+ D AA++ A GRK+ V ++PATQK++++ A
Sbjct: 290 ISIDQAVIGSCTNGRLSDIKVAAEI--ARGRKIAENVRCIVIPATQKIYLE--------A 339
Query: 354 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEP-QVCVSTTNRNFPGRMGHKEG 178
K + EAG ++P+CG CLGG Y + P + C+STTNRNF GRMG
Sbjct: 340 MEKGYIKDLIEAGA-VVSTPTCGPCLGG----YMGILAPNERCISTTNRNFVGRMGDASS 394
Query: 177 QIYLASPYTAAASALTGRVADPRE 106
+IYLASP A ASA+ G +A P +
Sbjct: 395 EIYLASPEVAMASAVLGYIASPSD 418
[239][TOP]
>UniRef100_A1HUD1 Homoaconitate hydratase family protein n=1 Tax=Thermosinus
carboxydivorans Nor1 RepID=A1HUD1_9FIRM
Length = 419
Score = 95.9 bits (237), Expect = 2e-18
Identities = 60/143 (41%), Positives = 85/143 (59%), Gaps = 2/143 (1%)
Frame = -3
Query: 522 IDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVK--VPTFLVPATQKVWMDVYALPVPGAGG 349
I + Y+GSCT G+ D + AAK+ GRKV V + PA++ ++ A
Sbjct: 291 IHQAYLGSCTNGRYPDLVEAAKILK--GRKVHPDVRLLVSPASRSIYHR--------AVR 340
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ +I +AG A PSCGACLG + AR + +S+TNRNF GRMGHKE +I+
Sbjct: 341 EGIIEILSDAGAMILA-PSCGACLGLHSGILAR---GERAISSTNRNFVGRMGHKEAEIF 396
Query: 168 LASPYTAAASALTGRVADPREFL 100
LASP + AA+A+ G++ DPR+FL
Sbjct: 397 LASPASVAAAAIEGKITDPRKFL 419
[240][TOP]
>UniRef100_A1HLS2 3-isopropylmalate dehydratase, large subunit n=1 Tax=Thermosinus
carboxydivorans Nor1 RepID=A1HLS2_9FIRM
Length = 420
Score = 95.9 bits (237), Expect = 2e-18
Identities = 56/142 (39%), Positives = 79/142 (55%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
D+ ID+V IGSCT G+ ED AA + +V ++P +Q V+++ A
Sbjct: 288 DIAIDQVVIGSCTNGRLEDLAQAAAILEGKTVHPRVRAIVIPGSQAVYLE--------AM 339
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ + F AG ++P+CG CLGG A + V+TTNRNF GRMGH + ++
Sbjct: 340 QRGYIETFIRAGA-VVSTPTCGPCLGGYMGILAA---GERAVATTNRNFRGRMGHVDSEV 395
Query: 171 YLASPYTAAASALTGRVADPRE 106
YLA P AAASA+ GR+A P E
Sbjct: 396 YLAGPAVAAASAVLGRIAAPWE 417
[241][TOP]
>UniRef100_C8SBC1 Homoaconitate hydratase family protein n=1 Tax=Ferroglobus placidus
DSM 10642 RepID=C8SBC1_FERPL
Length = 427
Score = 95.9 bits (237), Expect = 2e-18
Identities = 57/145 (39%), Positives = 84/145 (57%), Gaps = 2/145 (1%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLV--PATQKVWMDVYALPVPGA 355
VK+D+V++G+CT G+ D A++ GRKV L+ PA+++V+M
Sbjct: 297 VKVDQVFVGTCTNGRLSDLEVVARILK--GRKVHKDVRLLVGPASREVYMKALERGY--- 351
Query: 354 GGKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQ 175
+I + G P P CG C+G A + +VC+ST NRNF GRMG+ +
Sbjct: 352 ----IQEIIKAGGVILP--PGCGPCVGIHLGILA---DGEVCLSTQNRNFKGRMGNPNAE 402
Query: 174 IYLASPYTAAASALTGRVADPREFL 100
IYL+SP TAAASA+ G++ADPR++L
Sbjct: 403 IYLSSPATAAASAIEGKIADPRKYL 427
[242][TOP]
>UniRef100_C3XJX6 3-isopropylmalate dehydratase large subunit n=1 Tax=Helicobacter
winghamensis ATCC BAA-430 RepID=C3XJX6_9HELI
Length = 422
Score = 95.5 bits (236), Expect = 2e-18
Identities = 53/141 (37%), Positives = 79/141 (56%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
++KID+ +IGSCT G+ D A+++ V + P TQ+++ D + L
Sbjct: 292 NLKIDQAFIGSCTNGRLSDLKIASEILKGKKVHKDVRLIITPGTQQIYKDAHKLGY---- 347
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
I +AG ++P+CGACLGG L + + CVSTTNRNF GRMG + ++
Sbjct: 348 ----IDILLDAGA-LISNPTCGACLGGYMGI---LGDNERCVSTTNRNFIGRMGARNSEV 399
Query: 171 YLASPYTAAASALTGRVADPR 109
YLA+ A SA+ G++ADPR
Sbjct: 400 YLANSAVVAISAIKGKIADPR 420
[243][TOP]
>UniRef100_Q7VH31 3-isopropylmalate dehydratase large subunit n=1 Tax=Helicobacter
hepaticus RepID=LEUC_HELHP
Length = 420
Score = 95.5 bits (236), Expect = 2e-18
Identities = 55/142 (38%), Positives = 81/142 (57%)
Frame = -3
Query: 531 DVKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAG 352
++KID+V IGSCT G+ D AA++ ++PATQ ++++
Sbjct: 289 EIKIDQVVIGSCTNGRLSDMAVAAEILKDKTIAKNTRCIIIPATQNIYLECI-------- 340
Query: 351 GKTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQI 172
+ + F +AG ++P+CG CLGG A NE CVSTTNRNF GRMGH ++
Sbjct: 341 NRGYLETFIKAGA-VVSTPTCGPCLGGHMGILAA-NEK--CVSTTNRNFVGRMGHITSEV 396
Query: 171 YLASPYTAAASALTGRVADPRE 106
YL+SP AAASA+ G ++ P++
Sbjct: 397 YLSSPEVAAASAVRGILSAPQD 418
[244][TOP]
>UniRef100_Q703X6 3-isopropylmalate dehydratase large subunit n=1 Tax=Thermoproteus
tenax RepID=Q703X6_THETE
Length = 415
Score = 95.1 bits (235), Expect = 3e-18
Identities = 55/143 (38%), Positives = 81/143 (56%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
V++D+V+IGSCT G+ D AAA++ + K +PA+ V+ AG
Sbjct: 287 VEVDQVFIGSCTNGRLSDIEAAARILKRG--RAKARCIAIPASYSVFRQALE-----AG- 338
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ +AGC +CG C+GG + L + VST+NRNF GRMG + ++Y
Sbjct: 339 --YIDVLTKAGCVVTYG-TCGPCIGGH---FGVLGPGETAVSTSNRNFVGRMGANDSKVY 392
Query: 168 LASPYTAAASALTGRVADPREFL 100
LA+ YTAAA+AL GR+ DPR++L
Sbjct: 393 LANAYTAAAAALEGRIVDPRKYL 415
[245][TOP]
>UniRef100_B0K0Y2 3-isopropylmalate dehydratase large subunit n=4
Tax=Thermoanaerobacter RepID=LEUC_THEPX
Length = 418
Score = 95.1 bits (235), Expect = 3e-18
Identities = 55/141 (39%), Positives = 78/141 (55%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
VKID+V IGSCT G+ D A K+ V + PATQ+++++
Sbjct: 288 VKIDQVVIGSCTNGRLSDMEIAYKILKGKKVHPDVRLLIFPATQEIYLECVK-------- 339
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ + F +AG ++P+CG CLGG AR + ++TTNRNF GRMGH E ++Y
Sbjct: 340 RGYIEEFIKAGAAV-STPTCGPCLGGHMGILAR---GERALATTNRNFVGRMGHPESEVY 395
Query: 168 LASPYTAAASALTGRVADPRE 106
L+SP AAASA+ G + P E
Sbjct: 396 LSSPAVAAASAIAGYIVSPEE 416
[246][TOP]
>UniRef100_Q3Z894 3-isopropylmalate dehydratase, large subunit n=1
Tax=Dehalococcoides ethenogenes 195 RepID=Q3Z894_DEHE1
Length = 416
Score = 94.7 bits (234), Expect = 4e-18
Identities = 55/141 (39%), Positives = 80/141 (56%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+K+D+V IGSCT G+ ED +AKL + T ++P +Q+V++D AG
Sbjct: 287 IKVDQVIIGSCTNGRLEDLAISAKLLEGNKVSPDLRTIVIPGSQQVYLDALK-----AG- 340
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ F AG ++P+CG CLGG A + C++TTNRNF GRMG + ++Y
Sbjct: 341 --YIETFINAGVAV-STPTCGPCLGGHMGILAA---GERCLATTNRNFVGRMGSPKSEVY 394
Query: 168 LASPYTAAASALTGRVADPRE 106
LA P AAA+A+ G +A P E
Sbjct: 395 LAGPAVAAATAIKGYIAHPDE 415
[247][TOP]
>UniRef100_C6PJB4 3-isopropylmalate dehydratase, large subunit n=1
Tax=Thermoanaerobacter italicus Ab9 RepID=C6PJB4_9THEO
Length = 418
Score = 94.7 bits (234), Expect = 4e-18
Identities = 55/141 (39%), Positives = 78/141 (55%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
VKID+V IGSCT G+ D A K+ V + PATQ+++++
Sbjct: 288 VKIDQVVIGSCTNGRLSDMEIAYKILKGKKVHPDVRLLIFPATQEIYLECVK-------- 339
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ + F +AG ++P+CG CLGG AR + ++TTNRNF GRMGH E ++Y
Sbjct: 340 RGYIEEFIKAGAAI-STPTCGPCLGGHMGILAR---GERALATTNRNFVGRMGHPESEVY 395
Query: 168 LASPYTAAASALTGRVADPRE 106
L+SP AAASA+ G + P E
Sbjct: 396 LSSPAVAAASAIAGYIVSPEE 416
[248][TOP]
>UniRef100_A8RTF7 Putative uncharacterized protein n=1 Tax=Clostridium bolteae ATCC
BAA-613 RepID=A8RTF7_9CLOT
Length = 432
Score = 94.7 bits (234), Expect = 4e-18
Identities = 54/139 (38%), Positives = 77/139 (55%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
V+ID+ ++G+CTGG+ ED AA++ V ++PA+ +V + A
Sbjct: 286 VRIDQAFVGACTGGRVEDIGEAARILKGRTIAPHVRMVVIPASAEVLKECIA-------- 337
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
K +AG T ++P CG CL A +VCV+T+NRNFPGRMG ++ +Y
Sbjct: 338 KGFLDTLIDAGA-TISAPGCGPCLSAHQGVLAA---GEVCVTTSNRNFPGRMGSRDSAVY 393
Query: 168 LASPYTAAASALTGRVADP 112
LASP T A SALTG + DP
Sbjct: 394 LASPATVAMSALTGYLTDP 412
[249][TOP]
>UniRef100_A8CP51 3-isopropylmalate dehydratase, large subunit n=1
Tax=Dehalococcoides sp. VS RepID=A8CP51_9CHLR
Length = 416
Score = 94.7 bits (234), Expect = 4e-18
Identities = 55/141 (39%), Positives = 80/141 (56%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
+K+D+V IGSCT G+ ED +AKL + T ++P +Q+V++D AG
Sbjct: 287 IKVDQVIIGSCTNGRLEDLAISAKLLEVNKVNPDLRTIVIPGSQQVYLDALK-----AG- 340
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ F AG ++P+CG CLGG A + C++TTNRNF GRMG + ++Y
Sbjct: 341 --YIETFINAGVAV-STPTCGPCLGGHMGILAA---GERCLATTNRNFVGRMGSPKSEVY 394
Query: 168 LASPYTAAASALTGRVADPRE 106
LA P AAA+A+ G +A P E
Sbjct: 395 LAGPAVAAATAIKGYIAHPDE 415
[250][TOP]
>UniRef100_B1YD98 3-isopropylmalate dehydratase large subunit n=1 Tax=Thermoproteus
neutrophilus V24Sta RepID=LEUC_THENV
Length = 415
Score = 94.7 bits (234), Expect = 4e-18
Identities = 53/143 (37%), Positives = 80/143 (55%)
Frame = -3
Query: 528 VKIDRVYIGSCTGGKTEDFMAAAKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGG 349
V++D+V+IGSCT G+ DF AA++ + K +PA+ V+ L
Sbjct: 285 VEVDQVFIGSCTNGRLSDFEVAARVLKRG--RAKARCIAIPASYAVFRRAMELGY----- 337
Query: 348 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 169
+ +AGC +CG CLGG + +V V+T+NRNF GR+GH + ++Y
Sbjct: 338 ---IDVLTKAGCVVTYG-TCGPCLGGH---FGVAGPGEVVVTTSNRNFKGRVGHPDSKVY 390
Query: 168 LASPYTAAASALTGRVADPREFL 100
LA+P TAAA+AL G++ DPR +L
Sbjct: 391 LANPATAAAAALEGKIVDPRPYL 413