Human ORFeome
Gene/Protein Characteristic Table for ORH09959
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Product ID ORH09959
Clone name on19334
IMAGE Clone ID 100011107
Vector name pENTR221
Stop codon without
Genbank Acc DQ896647
Parent Genbank Acc BC009989
Parent gene symbol SMO
Description Homo sapiens smoothened homolog (Drosophila), mRNA (cDNA clone MGC:15193 IMAGE:4127774), complete cds.
Features of the cloned ORF sequence
Description

Length: 2361 bp

Restriction map

Features of the protein sequence
Description

Length: 787 aa

Result of homology search against nr database (FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
Q99835 0 100.0 Smoothened homo...
Homo sapiens
XP_519371 0 99.0 smoothened isof...
Pan troglodytes
XP_001093150 0 98.5 similar to smoo...
Macaca mulatta
XP_001501725 0 96.0 smoothened [Equ...
Equus caballus
XP_586374 0 94.6 similar to smoo...
Bos taurus
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of homology search against ORFeome database (FASTA output, Multiple alignment)
Entry Exp ID%
on36628 4.6e-19 54.2
on24115 1.2e-18 55.0
on23043 1.3e-18 55.2
on15754 3.7e-16 57.7
on19383 3.7e-16 57.7
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)

Result of InterProScan

Search method interpro_ID From To Entry Definition
FPrintScan IPR000539 233 255 PR00489 Frizzled protein
IPR000539 262 284 PR00489 Frizzled protein
IPR000539 316 340 PR00489 Frizzled protein
IPR000539 360 383 PR00489 Frizzled protein
IPR000539 405 427 PR00489 Frizzled protein
IPR000539 448 469 PR00489 Frizzled protein
IPR000539 517 537 PR00489 Frizzled protein
HMMPfam IPR000024 64 179 PF01392 Frizzled CRD region
IPR000539 220 555 PF01534 Frizzled protein
HMMSmart IPR000024 69 183 SM00063 Frizzled CRD region
ProfileScan IPR000024 65 181 PS50038 Frizzled CRD region
IPR000832 231 493 PS50261 GPCR

Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length
SOSUI2 1 4 ARPARGPELPLLGLLLLLLLGDP 26 SECONDARY 23
2 233 YIAAFGAVTGLCTLFTLATFVAD 255 SECONDARY 23
3 263 PAVILFYVNACFFVGSIGWLAQF 285 PRIMARY 23
4 313 SCVIIFVIVYYALMAGVVWFVVL 335 PRIMARY 23
5 362 LLTWSLPFVLTVAILAVAQVDGD 384 PRIMARY 23
6 403 FVLAPIGLVLIVGGYFLIRGVMT 425 PRIMARY 23
7 449 MLRLGIFGFLAFGFVLITFSCHF 471 PRIMARY 23
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