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[1][TOP]
>UniRef100_Q672H5 5-alpha-reductase n=1 Tax=Pisum sativum RepID=Q672H5_PEA
Length = 271
Score = 333 bits (854), Expect = 6e-90
Identities = 158/190 (83%), Positives = 172/190 (90%), Gaps = 1/190 (0%)
Frame = +1
Query: 28 FQKEDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALW 207
F ++DSLFNYALLTLFLIAPPTFISL FLQAPYGKHHRPGWGPNLSPPLAWFLMESP LW
Sbjct: 7 FLQDDSLFNYALLTLFLIAPPTFISLAFLQAPYGKHHRPGWGPNLSPPLAWFLMESPTLW 66
Query: 208 FTLYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTR-RKKSSLSKTPSGFPL 384
FTLYLFP G NSSNPKSIILITPFLIHYFNRTIIYP RLF+T + +KKS+LSKTPSGFP
Sbjct: 67 FTLYLFPFGNNSSNPKSIILITPFLIHYFNRTIIYPVRLFITMKTKKKSTLSKTPSGFPF 126
Query: 385 SIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLR 564
SIA MAF+FNLLNSYVQA+WVSHYK+YD+GL FW VFF G+LVF MGIN+WSDK LLR
Sbjct: 127 SIALMAFVFNLLNSYVQARWVSHYKSYDDGLFFWVVFFCGVLVFSGGMGINVWSDKELLR 186
Query: 565 LXGEGKGYMI 594
L GEGKGY++
Sbjct: 187 LKGEGKGYVV 196
[2][TOP]
>UniRef100_Q9FR36 Putative steroid reductase n=1 Tax=Glycine max RepID=Q9FR36_SOYBN
Length = 263
Score = 261 bits (667), Expect = 3e-68
Identities = 128/192 (66%), Positives = 146/192 (76%), Gaps = 1/192 (0%)
Frame = +1
Query: 22 PFFQKEDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPA 201
P + SLF+ +LLTLFLIAPPTF SLTFLQAPYGKHHRPGWGPNL PPLAW LMESP
Sbjct: 3 PEHYSDSSLFHSSLLTLFLIAPPTFFSLTFLQAPYGKHHRPGWGPNLPPPLAWLLMESPT 62
Query: 202 LWFTLYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFP 381
LW TL LFP G +S NPK+ LITPFLIHYFNRTI+YP L LT + KT GFP
Sbjct: 63 LWLTLLLFPLGLHSHNPKAQALITPFLIHYFNRTILYPLHLLLTPSK------KTTPGFP 116
Query: 382 LSIAFMAFLFNLLNSYVQAKWVSHYKN-YDNGLCFWGVFFGGLLVFFVXMGINIWSDKVL 558
LS+A MAF FN+LNSY+QA+ VSHY N YD+ FW F GLLVF + MGIN+W+D+VL
Sbjct: 117 LSVALMAFAFNVLNSYLQARTVSHYNNHYDDSGFFWFRFLCGLLVFLLGMGINVWADRVL 176
Query: 559 LRLXGEGKGYMI 594
LRL EGKGY++
Sbjct: 177 LRLKSEGKGYVV 188
[3][TOP]
>UniRef100_B9IG44 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9IG44_POPTR
Length = 257
Score = 249 bits (637), Expect = 9e-65
Identities = 119/187 (63%), Positives = 146/187 (78%), Gaps = 1/187 (0%)
Frame = +1
Query: 37 EDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTL 216
+ SLF+Y+LL+++LI PPTFISL FLQAPYGKHHRPGWGP +SPPLAW LMESP LW TL
Sbjct: 5 DQSLFHYSLLSIYLIGPPTFISLKFLQAPYGKHHRPGWGPTISPPLAWILMESPTLWLTL 64
Query: 217 YLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAF 396
LFP+G++ +NPK+IIL++PFL+HYF+RT IYP R++ SKT GFP+S+A
Sbjct: 65 LLFPYGQHFTNPKAIILMSPFLLHYFHRTCIYPLRIYRN--------SKTTGGFPVSVAV 116
Query: 397 MAFLFNLLNSYVQAKWVSHYK-NYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXG 573
MAF FNLLN+Y+QA+WVSHYK +YD GL FW FFGGL+VF M IN W+D VLL L
Sbjct: 117 MAFGFNLLNAYLQARWVSHYKSDYDGGL-FWWKFFGGLVVFVWGMRINTWADGVLLGLKR 175
Query: 574 EGKGYMI 594
EG GY +
Sbjct: 176 EGGGYKV 182
[4][TOP]
>UniRef100_B9SPE4 3-oxo-5-alpha-steroid 4-dehydrogenase, putative n=1 Tax=Ricinus
communis RepID=B9SPE4_RICCO
Length = 263
Score = 243 bits (619), Expect = 1e-62
Identities = 112/187 (59%), Positives = 144/187 (77%), Gaps = 1/187 (0%)
Frame = +1
Query: 37 EDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTL 216
+ SLF+ +LL L+LI PPTFISL FLQAPYGKH+RPGWGP +SPPLAWFLMESP LW T
Sbjct: 5 DGSLFHKSLLALYLIGPPTFISLKFLQAPYGKHNRPGWGPTISPPLAWFLMESPTLWLTF 64
Query: 217 YLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAF 396
LFP G+++SNPK+ +L+ P+L HYF+RT +YP RL+ T ++ +K SGFP+S+A
Sbjct: 65 LLFPFGQHASNPKAWVLMFPYLFHYFHRTCLYPLRLYWNTNQRN---TKITSGFPVSMAL 121
Query: 397 MAFLFNLLNSYVQAKWVSHYK-NYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXG 573
+AFLFN LN+Y+QA+WVSHYK +YD FW F+GGL+VF M N+WSD+VL+RL
Sbjct: 122 LAFLFNFLNAYLQARWVSHYKEDYDQDRWFWWRFWGGLVVFAWGMWTNVWSDRVLVRLKR 181
Query: 574 EGKGYMI 594
EG GY +
Sbjct: 182 EGDGYKV 188
[5][TOP]
>UniRef100_Q2QDF6 Steroid 5-alpha-reductase n=1 Tax=Gossypium hirsutum
RepID=Q2QDF6_GOSHI
Length = 258
Score = 233 bits (595), Expect = 7e-60
Identities = 110/184 (59%), Positives = 139/184 (75%), Gaps = 1/184 (0%)
Frame = +1
Query: 37 EDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTL 216
+ +LF+Y LLTL++IA PT+ISL FLQAPYGKH+RPGWGP +SPPLAWFLMESP LW T
Sbjct: 4 DQTLFHYCLLTLYIIALPTWISLYFLQAPYGKHNRPGWGPTISPPLAWFLMESPTLWLTF 63
Query: 217 YLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAF 396
+LFP G++ NPKS +LI+PFL HYFNRT++YP RL T + + GFP+S+AF
Sbjct: 64 FLFPSGQHFYNPKSFLLISPFLFHYFNRTVLYPLRLARNTTQTR--------GFPVSVAF 115
Query: 397 MAFLFNLLNSYVQAKWVSHYK-NYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXG 573
MAF FNLLN Y+QA+WVSHYK +Y+N FW F GLL+F V M +N+ +DKVL+ L
Sbjct: 116 MAFGFNLLNGYLQARWVSHYKDDYENEELFWWRFLAGLLIFVVGMWVNVRADKVLVGLKK 175
Query: 574 EGKG 585
+G G
Sbjct: 176 QGDG 179
[6][TOP]
>UniRef100_Q8H1T2 Steroid 5-alpha-reductase n=1 Tax=Gossypium hirsutum
RepID=Q8H1T2_GOSHI
Length = 258
Score = 233 bits (593), Expect = 1e-59
Identities = 110/184 (59%), Positives = 138/184 (75%), Gaps = 1/184 (0%)
Frame = +1
Query: 37 EDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTL 216
+ +LF+Y LLTL++IA PT+ISL FLQAPYGKH+RPGWGP +SPPLAWFLMESP LW T
Sbjct: 4 DQTLFHYCLLTLYIIALPTWISLYFLQAPYGKHNRPGWGPTISPPLAWFLMESPTLWLTF 63
Query: 217 YLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAF 396
+LFP G++ NPKS +LI+PFL HYFNRT++YP RL T + + GFP+S+AF
Sbjct: 64 FLFPSGQHFYNPKSFLLISPFLFHYFNRTVLYPLRLARNTTQTR--------GFPVSVAF 115
Query: 397 MAFLFNLLNSYVQAKWVSHYKN-YDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXG 573
MAF FNLLN Y+QA+WVSHYK+ Y N FW F GLL+F V M +N+ +DKVL+ L
Sbjct: 116 MAFGFNLLNGYLQARWVSHYKDXYXNEELFWWRFLXGLLIFVVGMWVNVXADKVLVGLKK 175
Query: 574 EGKG 585
+G G
Sbjct: 176 QGDG 179
[7][TOP]
>UniRef100_Q76EK9 Steroid 5alpha-reductase n=1 Tax=Ipomoea nil RepID=Q76EK9_IPONI
Length = 266
Score = 229 bits (584), Expect = 1e-58
Identities = 101/188 (53%), Positives = 139/188 (73%)
Frame = +1
Query: 31 QKEDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWF 210
+ + LF +++ L LIAPP +I+ F+ AP+GKH RPGWGP +SPPLAWFLMESPA+W
Sbjct: 9 ESDQWLFRHSVFVLLLIAPPVYIACRFITAPFGKHVRPGWGPTISPPLAWFLMESPAIWL 68
Query: 211 TLYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSI 390
TL LFP G++SSNP + IL+ P+L+HY +RTI+YP RL+L + ++++ +GFP+S+
Sbjct: 69 TLLLFPFGRSSSNPLAQILMAPYLLHYAHRTIVYPLRLYLNSDPRRAA-----AGFPVSV 123
Query: 391 AFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLX 570
A MAF FN+LN+Y+Q +WVSHY +Y+ G FW F G+ VF M +N+W+DKVLLRL
Sbjct: 124 ALMAFTFNILNAYLQTRWVSHYADYEGGGLFWWRFACGMAVFLAGMAVNVWADKVLLRLK 183
Query: 571 GEGKGYMI 594
EG GY I
Sbjct: 184 SEGGGYKI 191
[8][TOP]
>UniRef100_Q38944 Probable steroid reductase DET2 n=1 Tax=Arabidopsis thaliana
RepID=DET2_ARATH
Length = 262
Score = 221 bits (563), Expect = 3e-56
Identities = 104/184 (56%), Positives = 134/184 (72%), Gaps = 1/184 (0%)
Frame = +1
Query: 37 EDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTL 216
+ + F Y LLTL PPT + L FLQAPYGKH+R GWGP +SPP+AWF+MESP LW TL
Sbjct: 6 DKTFFRYCLLTLIFAGPPTAVLLKFLQAPYGKHNRTGWGPTVSPPIAWFVMESPTLWLTL 65
Query: 217 YLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAF 396
LFP G+++ NPKS++L +P+LIHYF+RTIIYP RLF +SS +GFP++IA
Sbjct: 66 LLFPFGRHALNPKSLLLFSPYLIHYFHRTIIYPLRLF------RSSFPAGKNGFPITIAA 119
Query: 397 MAFLFNLLNSYVQAKWVSHYK-NYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXG 573
+AF FNLLN Y+QA+WVSHYK +Y++G FW F G++VF M INI SD+ L+RL
Sbjct: 120 LAFTFNLLNGYIQARWVSHYKDDYEDGNWFWWRFVIGMVVFITGMYINITSDRTLVRLKK 179
Query: 574 EGKG 585
E +G
Sbjct: 180 ENRG 183
[9][TOP]
>UniRef100_A7PP01 Chromosome chr8 scaffold_23, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7PP01_VITVI
Length = 257
Score = 215 bits (547), Expect = 2e-54
Identities = 101/184 (54%), Positives = 134/184 (72%)
Frame = +1
Query: 43 SLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYL 222
+LF+ +L+ L+LIAPPTFISL FLQAPYGKHHR GWGP + P LAWFLMESP +W TL +
Sbjct: 6 TLFHNSLIALYLIAPPTFISLRFLQAPYGKHHRSGWGPTVPPSLAWFLMESPTVWLTLLI 65
Query: 223 FPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMA 402
+P G SSNP+S+ILI+ +L HY +RT+IYP L +T K+ +GFP+S+A MA
Sbjct: 66 YPLGDRSSNPRSLILISIYLFHYIHRTLIYPLHLRNSTAAKR-------NGFPVSVALMA 118
Query: 403 FLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK 582
F FNLLN+Y+QA+WVSHY NY++ FW F+ GL++F M +N+ SD L+ L +G
Sbjct: 119 FGFNLLNAYLQARWVSHYANYEDDGWFWWRFWVGLVIFLDGMLVNVRSDLALVGLKSQGG 178
Query: 583 GYMI 594
GY +
Sbjct: 179 GYKV 182
[10][TOP]
>UniRef100_A5B1R9 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5B1R9_VITVI
Length = 257
Score = 215 bits (547), Expect = 2e-54
Identities = 101/184 (54%), Positives = 134/184 (72%)
Frame = +1
Query: 43 SLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYL 222
+LF+ +L+ L+LIAPPTFISL FLQAPYGKHHR GWGP + P LAWFLMESP +W TL +
Sbjct: 6 TLFHNSLIALYLIAPPTFISLRFLQAPYGKHHRXGWGPTVPPSLAWFLMESPTVWLTLLI 65
Query: 223 FPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMA 402
+P G SSNP+S+ILI+ +L HY +RT+IYP L +T K+ +GFP+S+A MA
Sbjct: 66 YPLGDRSSNPRSLILISIYLFHYIHRTLIYPLHLRNSTAAKR-------NGFPVSVALMA 118
Query: 403 FLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK 582
F FNLLN+Y+QA+WVSHY NY++ FW F+ GL++F M +N+ SD L+ L +G
Sbjct: 119 FGFNLLNAYLQARWVSHYANYEDDGWFWWRFWVGLVIFLDGMLVNVRSDLALVGLKSQGG 178
Query: 583 GYMI 594
GY +
Sbjct: 179 GYKV 182
[11][TOP]
>UniRef100_B9I5J5 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9I5J5_POPTR
Length = 264
Score = 209 bits (531), Expect = 2e-52
Identities = 98/188 (52%), Positives = 136/188 (72%), Gaps = 2/188 (1%)
Frame = +1
Query: 37 EDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTL 216
+ S F+Y+LL +L+ PTFI+L F Q PYGKH+R GWGP + PPLAWF+MESP++ L
Sbjct: 5 DQSFFHYSLLAYYLLGLPTFIALRFFQFPYGKHNRLGWGPTIPPPLAWFIMESPSILLPL 64
Query: 217 YLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAF 396
LFP G++ +NPK+++L++P+L+HYF+RT IYP R++ +T ++ +KT GFPL +AF
Sbjct: 65 ILFPLGQHFTNPKALVLMSPYLLHYFHRTFIYPLRIYQSTSQQN---TKTTIGFPLILAF 121
Query: 397 MAFLFNLLNSYVQAKWVSHYK-NYD-NGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLX 570
FL LN+Y+QA+WVSHYK +YD +G FW FFGGL+VF M IN+W+D LL L
Sbjct: 122 NGFLTQALNTYIQARWVSHYKSDYDSDGGLFWWKFFGGLVVFLWGMRINMWADTALLVLK 181
Query: 571 GEGKGYMI 594
E GY +
Sbjct: 182 RESGGYKV 189
[12][TOP]
>UniRef100_B9MZI8 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9MZI8_POPTR
Length = 264
Score = 201 bits (512), Expect = 3e-50
Identities = 95/189 (50%), Positives = 136/189 (71%), Gaps = 3/189 (1%)
Frame = +1
Query: 37 EDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTL 216
+ SLF+Y+LLT +L+ P TF++L F Q PYG+HHR GWG +SPPLAWFL E+P++ L
Sbjct: 5 DQSLFHYSLLTFYLLGPLTFVALKFFQLPYGRHHRLGWGFTVSPPLAWFLFETPSILLPL 64
Query: 217 YLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAF 396
LFP G++ +N K+++L++P+L+HYF+RT IYP R++ +T ++ +KT S +S+
Sbjct: 65 LLFPLGQHFTNLKALLLMSPYLLHYFHRTCIYPLRVYHSTTQQN---TKTTSAVSVSMVL 121
Query: 397 MAFLFNLLNSYVQAKWVSHYK---NYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRL 567
+AF+ +LN+Y+Q +WVSHYK N D GL FW FFGGL+VF M IN+W+D VLL L
Sbjct: 122 LAFMLQVLNTYLQTRWVSHYKHDYNSDGGL-FWWKFFGGLVVFLWGMRINMWADTVLLGL 180
Query: 568 XGEGKGYMI 594
EG GY +
Sbjct: 181 KREGGGYKV 189
[13][TOP]
>UniRef100_A9NWW4 Putative uncharacterized protein n=1 Tax=Picea sitchensis
RepID=A9NWW4_PICSI
Length = 260
Score = 194 bits (492), Expect = 6e-48
Identities = 96/186 (51%), Positives = 122/186 (65%)
Frame = +1
Query: 37 EDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTL 216
+ +L+N AL + +A TFI +F++ PYG+H RPGWGP++SP LAWFLMESP LW +
Sbjct: 11 DKNLYNRALKAMLAMAVATFIPTSFIKVPYGRHSRPGWGPSISPRLAWFLMESPTLWMSA 70
Query: 217 YLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAF 396
LFPHG+ SSNP S+IL+ PFL HY +R IYP R+ S SK P+SIA
Sbjct: 71 LLFPHGRMSSNPTSLILLMPFLAHYIHRCCIYPLRI--------RSGSKP---LPISIAA 119
Query: 397 MAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGE 576
MAFLFN N+Y+Q +W+SHY NY G +F GLLVF M IN+W+D VLL L E
Sbjct: 120 MAFLFNTYNTYLQIRWISHYGNYTAGWLGSPMFIAGLLVFITGMIINLWADSVLLSLRRE 179
Query: 577 GKGYMI 594
+GY I
Sbjct: 180 NEGYKI 185
[14][TOP]
>UniRef100_Q5K2N1 Steroid 5 alpha reductase DET2 n=1 Tax=Solanum lycopersicum
RepID=Q5K2N1_SOLLC
Length = 257
Score = 182 bits (461), Expect = 2e-44
Identities = 91/190 (47%), Positives = 124/190 (65%), Gaps = 1/190 (0%)
Frame = +1
Query: 28 FQKEDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPG-WGPNLSPPLAWFLMESPAL 204
F +++LFN+ + + ++A PTFI F +PYGKH+ G +SPP+AW MESP L
Sbjct: 2 FSSDENLFNFIVFFILVMAFPTFILCQFFTSPYGKHYTSADSGTTISPPIAWAFMESPTL 61
Query: 205 WFTLYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPL 384
W T+ +F GKN +NP + +LI+P+L HY NRTIIYP RL R ++ T + FPL
Sbjct: 62 WLTIIVFRLGKNYTNPLAFLLISPYLFHYTNRTIIYPLRL-----RSRN----TKNNFPL 112
Query: 385 SIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLR 564
+IA AF+FNLLN+Y+Q++WVSHY NY FW F GL++F M +NIW+D VLL
Sbjct: 113 NIAVTAFIFNLLNAYIQSRWVSHYANYQEDDWFWVRFGIGLVIFGSGMLLNIWADGVLLG 172
Query: 565 LXGEGKGYMI 594
L +G GY I
Sbjct: 173 LKSQGGGYKI 182
[15][TOP]
>UniRef100_Q1W4D5 5-alpha-reductase n=1 Tax=Solanum chacoense RepID=Q1W4D5_SOLCH
Length = 257
Score = 179 bits (453), Expect = 2e-43
Identities = 91/190 (47%), Positives = 122/190 (64%), Gaps = 1/190 (0%)
Frame = +1
Query: 28 FQKEDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPG-WGPNLSPPLAWFLMESPAL 204
F +++LFN+ + + ++A PTFI F+ + YGKH+ G +SPP+AW MESP L
Sbjct: 2 FSSDENLFNFIVFFILVMAFPTFILCQFVTSSYGKHYTSADSGTTISPPIAWAFMESPTL 61
Query: 205 WFTLYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPL 384
W T +F GKN +NP + ILI+P+L HY NRTIIYP RL R +S T + FPL
Sbjct: 62 WLTFIVFRLGKNYTNPLAFILISPYLFHYINRTIIYPLRL-----RSRS----TKNNFPL 112
Query: 385 SIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLR 564
+IA F+FNLLN+Y+Q++WVSHY NY+ FW F GL +F M +NIW+D VLL
Sbjct: 113 NIAVTGFIFNLLNAYIQSRWVSHYANYEEDESFWVRFGIGLGLFGSGMLVNIWADGVLLG 172
Query: 565 LXGEGKGYMI 594
L +G GY I
Sbjct: 173 LKSQGGGYKI 182
[16][TOP]
>UniRef100_Q8SA55 3-oxo-5-alpha-steroid 4-dehydrogenase (Fragment) n=1 Tax=Pisum
sativum RepID=Q8SA55_PEA
Length = 72
Score = 148 bits (374), Expect = 3e-34
Identities = 66/71 (92%), Positives = 67/71 (94%)
Frame = +1
Query: 103 LTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFPHGKNSSNPKSIILITPFL 282
L FLQAPYGKHHRPGWGPNLSPPLAWFLMESP LWFTLYLFP G NSSNPKSIILITPFL
Sbjct: 1 LKFLQAPYGKHHRPGWGPNLSPPLAWFLMESPTLWFTLYLFPFGNNSSNPKSIILITPFL 60
Query: 283 IHYFNRTIIYP 315
IHYF+RTIIYP
Sbjct: 61 IHYFHRTIIYP 71
[17][TOP]
>UniRef100_Q5U9F1 3-oxo-5-alpha-steroid 4-dehydrogenase (Fragment) n=1 Tax=Humulus
lupulus RepID=Q5U9F1_HUMLU
Length = 144
Score = 131 bits (329), Expect = 5e-29
Identities = 65/130 (50%), Positives = 84/130 (64%)
Frame = +1
Query: 205 WFTLYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPL 384
W T LFP G +SS+PKS++LI+ FL+HYFNRT+ +P RL K P FP+
Sbjct: 1 WLTFLLFPFGIHSSDPKSLLLISFFLLHYFNRTVFFPLRLLR---------QKNPGDFPV 51
Query: 385 SIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLR 564
+IA AF FNLLN+Y+QA+ VSHY +YD FW FF G +VF M IN+ SD+VL+R
Sbjct: 52 AIAATAFGFNLLNAYLQARSVSHYSDYDGDEWFWWRFFAGAVVFLAGMAINVASDRVLVR 111
Query: 565 LXGEGKGYMI 594
L G GY +
Sbjct: 112 LKESGGGYKV 121
[18][TOP]
>UniRef100_B6TIF9 Steroid reductase DET2 n=1 Tax=Zea mays RepID=B6TIF9_MAIZE
Length = 262
Score = 119 bits (299), Expect = 1e-25
Identities = 76/187 (40%), Positives = 102/187 (54%), Gaps = 5/187 (2%)
Frame = +1
Query: 49 FNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALW---FTLY 219
F+ LL L+LI+P T ++L F+ APYGK RPGWGP L PLAWFLMESP LW L
Sbjct: 15 FDRCLLALYLISPLTVLALRFISAPYGKLSRPGWGPVLPAPLAWFLMESPTLWLPPLVLL 74
Query: 220 LFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFM 399
+P S P + + + HY +RT+++P RL + L + P+ PL IA
Sbjct: 75 RWP-PPPLSGPLAALPAALYAFHYVHRTLVHPLRL--------ARLRRAPAPVPLLIAAC 125
Query: 400 AFLFNLLNSYVQAKWVSHY--KNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXG 573
A FN+LN+Y+QA+ + + + C GL +F M NI +DK LLRL
Sbjct: 126 ALGFNILNAYLQARSFALHAGRQASPFRC-----LAGLALFAWGMRTNIAADKELLRLKE 180
Query: 574 EGKGYMI 594
G GY I
Sbjct: 181 AGGGYKI 187
[19][TOP]
>UniRef100_A2WX21 Putative uncharacterized protein n=1 Tax=Oryza sativa Indica Group
RepID=A2WX21_ORYSI
Length = 268
Score = 119 bits (299), Expect = 1e-25
Identities = 75/195 (38%), Positives = 103/195 (52%), Gaps = 9/195 (4%)
Frame = +1
Query: 37 EDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTL 216
+D+L+ L+TL+LI+P T L F+ APYGK RPGWGP + LAWFLMESP +
Sbjct: 7 DDALYARCLVTLYLISPITVFLLRFVSAPYGKLSRPGWGPAVPAALAWFLMESPTMCLPP 66
Query: 217 YLFPHGKNSSNPKSIILITP--FLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSI 390
+ +SS ++ L+ + +HY NRT+++P RL L + P+ P+ +
Sbjct: 67 LVLSAAASSSALRAAALLPAALYALHYVNRTLVHPLRLL--------RLRRAPAPVPILV 118
Query: 391 AFMAFLFNLLNSYVQAK-WVSHYKNYDNGLCFWGV------FFGGLLVFFVXMGINIWSD 549
A AF FNLLN+YVQA+ W + GL +F M NI +D
Sbjct: 119 AAFAFGFNLLNAYVQARSWALDAAAPHSTATATATPAAVARCLVGLALFAWGMRTNIAAD 178
Query: 550 KVLLRLXGEGKGYMI 594
K LLRL GKGY I
Sbjct: 179 KALLRLKEAGKGYQI 193
[20][TOP]
>UniRef100_Q8LQ34 Os01g0851600 protein n=1 Tax=Oryza sativa Japonica Group
RepID=Q8LQ34_ORYSJ
Length = 268
Score = 117 bits (293), Expect = 7e-25
Identities = 74/195 (37%), Positives = 102/195 (52%), Gaps = 9/195 (4%)
Frame = +1
Query: 37 EDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTL 216
+D+L+ L+ L+LI+P T L F+ APYGK RPGWGP + LAWFLMESP +
Sbjct: 7 DDALYARCLVILYLISPITVFLLRFVSAPYGKLSRPGWGPAVPAALAWFLMESPTMCLPP 66
Query: 217 YLFPHGKNSSNPKSIILITP--FLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSI 390
+ +SS ++ L+ + +HY NRT+++P RL L + P+ P+ +
Sbjct: 67 LVLSAAASSSALRAAALLPAALYALHYVNRTLVHPLRLL--------RLRRAPAPVPILV 118
Query: 391 AFMAFLFNLLNSYVQAK-WVSHYKNYDNGLCFWGV------FFGGLLVFFVXMGINIWSD 549
A AF FNLLN+YVQA+ W + GL +F M NI +D
Sbjct: 119 AAFAFGFNLLNAYVQARSWALDAAAPHSTATATATPAAVARCLVGLALFAWGMRTNIAAD 178
Query: 550 KVLLRLXGEGKGYMI 594
K LLRL GKGY I
Sbjct: 179 KALLRLKEAGKGYQI 193
[21][TOP]
>UniRef100_C7J8H0 Os11g0184100 protein n=2 Tax=Oryza sativa Japonica Group
RepID=C7J8H0_ORYSJ
Length = 272
Score = 116 bits (290), Expect = 2e-24
Identities = 73/191 (38%), Positives = 99/191 (51%), Gaps = 6/191 (3%)
Frame = +1
Query: 40 DSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWF-TL 216
D L+ L+TL+L++P +L F+ APYGK RPGWGP + LAW LMESP LW L
Sbjct: 15 DVLYARCLVTLYLLSPLNVFALWFMSAPYGKLSRPGWGPTVPAALAWCLMESPTLWLPPL 74
Query: 217 YLFPHGKNSSNPKSIILITP---FLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLS 387
L + S P + I P +++HY +RT+++P RL L + P+ P+
Sbjct: 75 VLSATTTSLSTPTLRVTILPAALYMLHYVHRTLVHPLRLL--------RLRRAPAPMPIL 126
Query: 388 IAFMAFLFNLLNSYVQAK-WVSHYKNYDNGLCFW-GVFFGGLLVFFVXMGINIWSDKVLL 561
I F FNLLN+Y+QA+ W GL +F M NI +D+ LL
Sbjct: 127 IIMFGFSFNLLNAYIQARSWALDAVPPATATPLTVARCLVGLALFVWGMWTNIAADRELL 186
Query: 562 RLXGEGKGYMI 594
RL GKGY I
Sbjct: 187 RLKEAGKGYQI 197
[22][TOP]
>UniRef100_A2ZC62 Putative uncharacterized protein n=1 Tax=Oryza sativa Indica Group
RepID=A2ZC62_ORYSI
Length = 266
Score = 114 bits (286), Expect = 4e-24
Identities = 73/191 (38%), Positives = 99/191 (51%), Gaps = 6/191 (3%)
Frame = +1
Query: 40 DSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWF-TL 216
D L+ L+TL+L++P +L F+ APYGK RPGWGP + LAW LMESP LW L
Sbjct: 9 DVLYARCLVTLYLLSPLNVFALWFMSAPYGKLSRPGWGPTVPAALAWCLMESPTLWLPPL 68
Query: 217 YLFPHGKNSSNPKSIILITP---FLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLS 387
L + S P + I P +++HY +RT+++P RL L + P P+
Sbjct: 69 VLSTTTTSLSTPTLRVTILPAALYMLHYVHRTLVHPIRLL--------RLRRAPVPMPIL 120
Query: 388 IAFMAFLFNLLNSYVQAK-W-VSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLL 561
I F FNLLN+Y+QA+ W + GL +F M NI +D+ LL
Sbjct: 121 IIMFGFGFNLLNAYIQARSWALDAVPPATAAPLTVARCLVGLALFVWGMWTNIAADRELL 180
Query: 562 RLXGEGKGYMI 594
RL GKGY I
Sbjct: 181 RLKEAGKGYQI 191
[23][TOP]
>UniRef100_A9STK3 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9STK3_PHYPA
Length = 258
Score = 105 bits (262), Expect = 3e-21
Identities = 61/189 (32%), Positives = 94/189 (49%), Gaps = 3/189 (1%)
Frame = +1
Query: 37 EDSLFNYALLTLFLIAPPTFISLTF-LQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFT 213
++ + AL F +A F+ + F L APYG+H R GWG ++ W +MESPAL+
Sbjct: 7 DEEWYTIALWGYFAMAAIMFVLVNFCLSAPYGRHVRRGWGFSVPVREGWIIMESPALFVM 66
Query: 214 LYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIA 393
++ G+ +L+ +HYF+RT+++PFR + P ++
Sbjct: 67 ALVYHAGQFHLQHVPHVLLRMHQMHYFHRTLVFPFR-----------MRADGKAMPAAVV 115
Query: 394 FMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXG 573
F FN+ NSY+QA+W+SH Y + F G+ +F V NIW+D VLL L
Sbjct: 116 ASGFFFNVYNSYIQARWISHIGVYPSSWLTSPQFLLGVAIFLVGFLGNIWADNVLLNLRD 175
Query: 574 --EGKGYMI 594
E + Y I
Sbjct: 176 HKEDRSYKI 184
[24][TOP]
>UniRef100_A6L1S2 3-oxo-5-alpha-steroid 4-dehydrogenase n=2 Tax=Bacteroides
RepID=A6L1S2_BACV8
Length = 254
Score = 102 bits (254), Expect = 2e-20
Identities = 59/186 (31%), Positives = 96/186 (51%), Gaps = 5/186 (2%)
Frame = +1
Query: 49 FNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFP 228
F + LL + +A F++L +++A YG H P WG +++ L W LME+P LYL+
Sbjct: 6 FEFLLLAMSALAVIVFVALYYVRAGYGMFHTPKWGLSVNNKLGWVLMEAPVFLVMLYLWW 65
Query: 229 HGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFL 408
+ + + F +HYF R+ I+PF L K S PL+I M +
Sbjct: 66 NSSVRFDAAPFLFFLLFELHYFQRSFIFPF------------LMKGKSRMPLAIMLMGVV 113
Query: 409 FNLLNSYVQAKWVSHYKN---YDNGLCFWGVFFGGLLVFFVXMGINIWSDKVL--LRLXG 573
FN+LN +Q +W+ + Y + F+ G+++FF+ MGIN+ SD V+ LR G
Sbjct: 114 FNVLNGLMQGEWLFYLAPEGLYTDAWLSTPSFWLGVILFFIGMGINLHSDSVIRHLRKPG 173
Query: 574 EGKGYM 591
+ + Y+
Sbjct: 174 DTRHYL 179
[25][TOP]
>UniRef100_B6W0N3 Putative uncharacterized protein n=1 Tax=Bacteroides dorei DSM
17855 RepID=B6W0N3_9BACE
Length = 254
Score = 102 bits (254), Expect = 2e-20
Identities = 59/186 (31%), Positives = 96/186 (51%), Gaps = 5/186 (2%)
Frame = +1
Query: 49 FNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFP 228
F + LL + +A F++L +++A YG H P WG +++ L W LME+P LYL+
Sbjct: 6 FEFLLLAMSALAVIVFVALYYVRAGYGIFHTPKWGLSVNNKLGWVLMEAPVFLVMLYLWW 65
Query: 229 HGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFL 408
+ + + F +HYF R+ I+PF L K S PL+I M +
Sbjct: 66 NSSVRFDAAPFLFFLLFELHYFQRSFIFPF------------LMKGKSRMPLAIMLMGVV 113
Query: 409 FNLLNSYVQAKWVSHYKN---YDNGLCFWGVFFGGLLVFFVXMGINIWSDKVL--LRLXG 573
FN+LN +Q +W+ + Y + F+ G+++FF+ MGIN+ SD V+ LR G
Sbjct: 114 FNVLNGLMQGEWLFYLAPEGLYTDAWLSTPSFWFGIILFFIGMGINLHSDSVIRHLRKPG 173
Query: 574 EGKGYM 591
+ + Y+
Sbjct: 174 DTRHYL 179
[26][TOP]
>UniRef100_C3Q5N1 3-oxo-5-alpha-steroid 4-dehydrogenase n=2 Tax=Bacteroides
RepID=C3Q5N1_9BACE
Length = 254
Score = 102 bits (253), Expect = 3e-20
Identities = 58/186 (31%), Positives = 96/186 (51%), Gaps = 5/186 (2%)
Frame = +1
Query: 49 FNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFP 228
F + LL + +A F++L +++A YG H P WG +++ L W LME+P LYL+
Sbjct: 6 FEFLLLAMSALAVIVFVALYYVRAGYGMFHTPKWGLSVNNKLGWVLMEAPVFLVMLYLWW 65
Query: 229 HGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFL 408
+ + + F +HYF R+ ++PF L K S PL+I M +
Sbjct: 66 NSSVRFDAAPFLFFLLFELHYFQRSFLFPF------------LMKGKSRMPLAIMLMGVV 113
Query: 409 FNLLNSYVQAKWVSHYKN---YDNGLCFWGVFFGGLLVFFVXMGINIWSDKVL--LRLXG 573
FN+LN +Q +W+ + Y + F+ G+++FF+ MGIN+ SD V+ LR G
Sbjct: 114 FNVLNGLMQGEWLFYLAPEGLYTDAWLSTPSFWLGIILFFIGMGINLHSDSVIRHLRKPG 173
Query: 574 EGKGYM 591
+ + Y+
Sbjct: 174 DTRHYL 179
[27][TOP]
>UniRef100_A6G326 Putative membrane dehydrogenase protein n=1 Tax=Plesiocystis
pacifica SIR-1 RepID=A6G326_9DELT
Length = 256
Score = 101 bits (251), Expect = 5e-20
Identities = 62/184 (33%), Positives = 97/184 (52%), Gaps = 4/184 (2%)
Frame = +1
Query: 55 YALLTLFLI--APPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFP 228
+ L+T LI A T IS + + APYG+H WGP+L W LME+PA+ +++
Sbjct: 12 HRLVTWILIGLAVVTLISTSVMTAPYGRHTSKSWGPSLPSRWGWVLMETPAVVVFCWIYM 71
Query: 229 HGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFL 408
G++ +IL+ + HY RT ++PFR TR +K P+ + M L
Sbjct: 72 QGQHRFETVPLILLGLWQFHYVQRTYVFPFR----TRSEKR--------MPVFVCAMGAL 119
Query: 409 FNLLNSYVQAKWVSHYKNYD-NGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK- 582
F L+N+Y+ A+W+SH+ +YD L W ++ G + F IN +D +L+ L G+
Sbjct: 120 FQLINAYINARWISHWGSYDPQWLMDWRLWLGAGM-FLAGWAINFKADAMLIALREPGES 178
Query: 583 GYMI 594
GY I
Sbjct: 179 GYKI 182
[28][TOP]
>UniRef100_C6IAD5 3-oxo-5-alpha-steroid 4-dehydrogenase n=3 Tax=Bacteroides
RepID=C6IAD5_9BACE
Length = 253
Score = 99.8 bits (247), Expect = 1e-19
Identities = 61/186 (32%), Positives = 90/186 (48%), Gaps = 5/186 (2%)
Frame = +1
Query: 49 FNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFP 228
FN LL + L+A FI+L F++A YG WG +++ +AW LME+P +L+
Sbjct: 6 FNLLLLVMGLVALVVFIALYFVRAGYGMFRSRSWGISVNNKIAWILMEAPVFLVMGWLWW 65
Query: 229 HGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFL 408
H P + F +HYF R ++PF L K S P+ I M +
Sbjct: 66 HSDRRFLPVELTFFLFFQLHYFQRAFVFPF------------LMKGKSKMPVLILLMGVI 113
Query: 409 FNLLNSYVQAKWVSHY---KNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVL--LRLXG 573
FN+LN +Q +W+ + Y G F+ G L+FF MGIN SD V+ LR G
Sbjct: 114 FNILNGLMQGEWIFYLAPSDYYTPGWLLTPCFWIGTLLFFAGMGINWHSDSVIRHLRAPG 173
Query: 574 EGKGYM 591
+ + Y+
Sbjct: 174 DTRHYL 179
[29][TOP]
>UniRef100_UPI0001968E1A hypothetical protein BACCELL_00996 n=1 Tax=Bacteroides
cellulosilyticus DSM 14838 RepID=UPI0001968E1A
Length = 253
Score = 98.6 bits (244), Expect = 3e-19
Identities = 63/190 (33%), Positives = 94/190 (49%), Gaps = 5/190 (2%)
Frame = +1
Query: 37 EDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTL 216
E F L + +IA FI+L F++A YG WG +++ LAW LME+P L
Sbjct: 2 EQGTFQLFLGVMSIIALFVFIALYFVKAGYGMFRTASWGISINNKLAWMLMEAPVFIVML 61
Query: 217 YLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAF 396
L+ + ++ +I F +HYF R ++PF L K S PL+I
Sbjct: 62 LLWWNSARYNSIVPLIFFLLFQLHYFQRAFVFPF------------LLKGKSRMPLAIMM 109
Query: 397 MAFLFNLLNSYVQAKWVSHYKNYDNGLCFW---GVFFGGLLVFFVXMGINIWSDKVL--L 561
M LFNLLN ++Q +W+ + + W F G+L+FF MGIN +SD V+ L
Sbjct: 110 MGMLFNLLNGFMQGEWLFYLAPETLYMLDWLKTPQFIFGVLLFFTGMGINWYSDYVIRHL 169
Query: 562 RLXGEGKGYM 591
R G+ + Y+
Sbjct: 170 RKPGDTQHYL 179
[30][TOP]
>UniRef100_A5ZJS2 Putative uncharacterized protein n=1 Tax=Bacteroides caccae ATCC
43185 RepID=A5ZJS2_9BACE
Length = 253
Score = 98.2 bits (243), Expect = 4e-19
Identities = 65/188 (34%), Positives = 93/188 (49%), Gaps = 7/188 (3%)
Frame = +1
Query: 49 FNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFP 228
FN L + LIA FI+L F++A YG WG +S LAW LME+P +++
Sbjct: 6 FNLFLGIMSLIALIVFIALYFVKAGYGIFRTASWGVAISNKLAWILMEAPVFLVMCWMWV 65
Query: 229 HGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFL 408
H + +P ++ F IHYF R ++P L LT + K PL+I M L
Sbjct: 66 HSERRFDPVILMFFIFFQIHYFQRAFVFP--LLLTGKSK----------MPLAIMSMGIL 113
Query: 409 FNLLNSYVQAKWVSHYK-----NYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVL--LRL 567
FNLLN Y+Q +W+ H D + W F G L+FF M +N SD ++ LR
Sbjct: 114 FNLLNGYMQGQWIFHLAPEGMYGIDWFMSPW--FILGTLLFFTGMLVNWHSDYIIRHLRK 171
Query: 568 XGEGKGYM 591
G+ + Y+
Sbjct: 172 PGDTRHYL 179
[31][TOP]
>UniRef100_UPI0001B49BB9 putative membrane dehydrogenase protein n=1 Tax=Bacteroides
fragilis 3_1_12 RepID=UPI0001B49BB9
Length = 253
Score = 97.4 bits (241), Expect = 7e-19
Identities = 66/190 (34%), Positives = 91/190 (47%), Gaps = 9/190 (4%)
Frame = +1
Query: 49 FNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFP 228
FN LL + L+A FI+L F++A YG WG +++ LAW LME+P +L+
Sbjct: 6 FNLLLLIMSLVALVVFIALYFIRAGYGMFRSRSWGISVNNKLAWILMEAPVFLVMSWLWW 65
Query: 229 HGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFL 408
H P + F +HYF R ++PF L K S P+ I M L
Sbjct: 66 HSDRRFFPVELTFFLFFQLHYFQRAFVFPF------------LMKGKSKMPILILLMGVL 113
Query: 409 FNLLNSYVQAKWV-----SHYKNYDNGL--CFWGVFFGGLLVFFVXMGINIWSDKVL--L 561
FN+LN +Q +W+ S Y D L CFW G L+FF M IN SD V+ L
Sbjct: 114 FNILNGLMQGEWIFYLAPSGYYTADWLLSPCFW----IGTLLFFSGMLINWHSDSVIRNL 169
Query: 562 RLXGEGKGYM 591
R G+ + Y+
Sbjct: 170 RTSGDTRHYL 179
[32][TOP]
>UniRef100_Q8A618 3-oxo-5-alpha-steroid 4-dehydrogenase n=1 Tax=Bacteroides
thetaiotaomicron RepID=Q8A618_BACTN
Length = 253
Score = 97.4 bits (241), Expect = 7e-19
Identities = 63/186 (33%), Positives = 91/186 (48%), Gaps = 5/186 (2%)
Frame = +1
Query: 49 FNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFP 228
FN L + L A FI+L F++A YG WG +S LAW LME+P +++
Sbjct: 6 FNLFLGVMSLTALIVFIALYFVKAGYGIFRTASWGVAISNKLAWILMEAPVFLVMCWMWI 65
Query: 229 HGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFL 408
H + +P + F IHYF R ++P L LT + K PL+I M L
Sbjct: 66 HSERRFDPVILTFFVFFQIHYFQRAFVFP--LLLTGKSK----------MPLAIMSMGIL 113
Query: 409 FNLLNSYVQAKWVSHYK---NYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVL--LRLXG 573
FNLLN Y+Q +W+ + Y +G F G L+FF M +N SD ++ LR G
Sbjct: 114 FNLLNGYMQGEWIFYLSPEGMYHSGWFTSAWFIAGSLLFFAGMLMNWHSDYIIRHLRKPG 173
Query: 574 EGKGYM 591
+ + Y+
Sbjct: 174 DTRHYL 179
[33][TOP]
>UniRef100_C6IMZ3 3-oxo-5-alpha-steroid 4-dehydrogenase n=1 Tax=Bacteroides sp. 1_1_6
RepID=C6IMZ3_9BACE
Length = 253
Score = 97.4 bits (241), Expect = 7e-19
Identities = 63/186 (33%), Positives = 91/186 (48%), Gaps = 5/186 (2%)
Frame = +1
Query: 49 FNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFP 228
FN L + LIA FI+L F++A YG WG + LAW LME+P +++
Sbjct: 6 FNLFLGVMSLIALIVFIALYFVKAGYGIFRTASWGVAIPNKLAWILMEAPVFLVMCWMWM 65
Query: 229 HGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFL 408
H + +P + F IHYF R ++P L LT + K PL+I M L
Sbjct: 66 HSERRFDPVILTFFIFFQIHYFQRAFVFP--LLLTGKSK----------MPLAIMSMGIL 113
Query: 409 FNLLNSYVQAKWVSHYK---NYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVL--LRLXG 573
FNLLN Y+Q +W+ + Y +G F G L+FF M +N SD ++ LR G
Sbjct: 114 FNLLNGYMQGEWIFYLSPEGMYHSGWFTSAWFIAGSLLFFAGMLMNWHSDYIIRHLRKPG 173
Query: 574 EGKGYM 591
+ + Y+
Sbjct: 174 DTRHYL 179
[34][TOP]
>UniRef100_B3C5P0 Putative uncharacterized protein n=1 Tax=Bacteroides intestinalis
DSM 17393 RepID=B3C5P0_9BACE
Length = 253
Score = 95.5 bits (236), Expect = 3e-18
Identities = 63/190 (33%), Positives = 92/190 (48%), Gaps = 5/190 (2%)
Frame = +1
Query: 37 EDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTL 216
E F L + +IA FI+L F++A YG WG +++ LAW LME+P L
Sbjct: 2 EQGTFLLFLGAMSIIALFVFIALYFVKAGYGMFRTASWGISINNKLAWMLMEAPVFIVML 61
Query: 217 YLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAF 396
L+ + ++ +I F +HYF R ++PF L K S PL I
Sbjct: 62 LLWWNSARYNSIAPLIFFLLFQLHYFQRAFVFPF------------LLKGKSRMPLVIMM 109
Query: 397 MAFLFNLLNSYVQAKWVSHYKN---YDNGLCFWGVFFGGLLVFFVXMGINIWSDKVL--L 561
M LFNLLN ++Q +W+ + Y F G+L+FF MGIN +SD V+ L
Sbjct: 110 MGMLFNLLNGFMQGEWLFYLAPETLYPPEWLMTPQFIIGVLLFFTGMGINWYSDYVIRHL 169
Query: 562 RLXGEGKGYM 591
R G+ + Y+
Sbjct: 170 RKPGDTRHYL 179
[35][TOP]
>UniRef100_UPI000197B035 hypothetical protein BACCOPRO_01851 n=1 Tax=Bacteroides coprophilus
DSM 18228 RepID=UPI000197B035
Length = 254
Score = 94.7 bits (234), Expect = 5e-18
Identities = 59/190 (31%), Positives = 91/190 (47%), Gaps = 5/190 (2%)
Frame = +1
Query: 37 EDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTL 216
E+SL+ + ++A FI+L ++QA YG WG ++ W LME PA +F L
Sbjct: 2 EESLYQVLCYIMPILAIVVFIALFYIQAGYGIFQNKHWGISIPNRWGWVLMECPAFFFML 61
Query: 217 YLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAF 396
YL+ + P + F HY R+ I+P L + S P++I
Sbjct: 62 YLWISSPSRLQPTLLTFFILFETHYLQRSFIFPL------------LMRGKSRMPIAIML 109
Query: 397 MAFLFNLLNSYVQAKWVSHYKNYDNGLCFW---GVFFGGLLVFFVXMGINIWSDKVL--L 561
M LFNL+N ++ + + H + + W F GGLL+F MGIN+ SD V+ L
Sbjct: 110 MGILFNLINGFMIGEDLFHLASAERYSTSWMSSPTFIGGLLLFISGMGINLHSDHVIRHL 169
Query: 562 RLXGEGKGYM 591
R G+ + Y+
Sbjct: 170 RKPGDTRHYL 179
[36][TOP]
>UniRef100_UPI000180B706 PREDICTED: similar to steroid-5-alpha-reductase, alpha polypeptide
1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
n=1 Tax=Ciona intestinalis RepID=UPI000180B706
Length = 268
Score = 92.8 bits (229), Expect = 2e-17
Identities = 61/169 (36%), Positives = 88/169 (52%), Gaps = 3/169 (1%)
Frame = +1
Query: 97 ISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTL--YLFPHGKNSSNPKSIILI 270
I ++ + APYG++ WG ++ LAWFL E PA + Y N S P ++IL+
Sbjct: 39 IIVSGINAPYGRYTSSSWGLPINSKLAWFLQELPAFLIPVFSYFTMTSSNVSTP-ALILL 97
Query: 271 TPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVS 450
+ FL+HYFNRT IY ++ R K + P+ I MA F + N Y+Q+ ++
Sbjct: 98 SVFLLHYFNRTFIYSQKI----RGGKPT--------PILIFLMAMFFCICNGYMQSVFLL 145
Query: 451 HYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEG-KGYMI 594
NY F F GL++FF+ M IN+ D +L L EG KGY I
Sbjct: 146 QISNYREEYLFEWNFVVGLILFFLGMYINLECDSILRNLRKEGEKGYKI 194
[37][TOP]
>UniRef100_C9KSH5 3-oxo-5-alpha-steroid 4-dehydrogenase family protein n=1
Tax=Bacteroides finegoldii DSM 17565 RepID=C9KSH5_9BACE
Length = 259
Score = 92.4 bits (228), Expect = 2e-17
Identities = 61/190 (32%), Positives = 94/190 (49%), Gaps = 8/190 (4%)
Frame = +1
Query: 46 LFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLF 225
+FN L+ + +A F++L F++A YG WG ++ AW LME+P + YL+
Sbjct: 7 IFNCFLIAMSFLALLVFVALYFVKAGYGVFRTKSWGISIPNKTAWVLMEAPVFFVLFYLW 66
Query: 226 PHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAF 405
+N + +I F +HYF R+ I+PF L K S PL+I M
Sbjct: 67 ITSENPFSIPVLIFFLLFELHYFQRSFIFPF------------LMKGKSRMPLTIVGMGV 114
Query: 406 LFNLLNSYVQAKWVSHYKNYDNGLC-FWGVFFG-----GLLVFFVXMGINIWSDKVL--L 561
+FN+LN +QA + + D W F G+L+FF+ MGIN+ SD V+ L
Sbjct: 115 VFNVLNGIMQALGLFYLPVTDTVYSGGWHYFVSPHAILGMLLFFLGMGINLHSDYVIRHL 174
Query: 562 RLXGEGKGYM 591
R G+ + Y+
Sbjct: 175 RQPGDTRHYL 184
[38][TOP]
>UniRef100_C3QWW3 3-oxo-5-alpha-steroid 4-dehydrogenase n=2 Tax=Bacteroides
RepID=C3QWW3_9BACE
Length = 253
Score = 92.4 bits (228), Expect = 2e-17
Identities = 64/186 (34%), Positives = 86/186 (46%), Gaps = 5/186 (2%)
Frame = +1
Query: 49 FNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFP 228
FN L + LIA FI+L F++A YG WG +S LAW LME+P ++
Sbjct: 6 FNLFLGVMSLIALFVFIALYFVKAGYGIFRTASWGVAISNKLAWILMEAPVFVVMCVMWI 65
Query: 229 HGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFL 408
+ + P F IHYF R I+P L K S PL+I M L
Sbjct: 66 YSERRFEPVIFTFFLFFQIHYFQRAFIFPL------------LLKGKSKMPLAIMSMGVL 113
Query: 409 FNLLNSYVQAKWVSHY---KNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVL--LRLXG 573
FNLLN Y+Q KW+ + Y G F G L+FF M +N SD ++ LR G
Sbjct: 114 FNLLNGYMQGKWIFYLAPETMYQAGWFTSPWFIIGTLLFFAGMLLNWQSDYIIRHLRKPG 173
Query: 574 EGKGYM 591
+ + Y+
Sbjct: 174 DTRHYL 179
[39][TOP]
>UniRef100_C9KVK0 3-oxo-5-alpha-steroid 4-dehydrogenase family protein n=1
Tax=Bacteroides finegoldii DSM 17565 RepID=C9KVK0_9BACE
Length = 253
Score = 91.7 bits (226), Expect = 4e-17
Identities = 60/186 (32%), Positives = 87/186 (46%), Gaps = 5/186 (2%)
Frame = +1
Query: 49 FNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFP 228
FN L + LIA F++L F++A YG WG +S LAW LME+P ++
Sbjct: 6 FNLFLGVMSLIALIVFVALYFVKAGYGIFRTSSWGAAISNKLAWILMEAPVFLVMCVMWM 65
Query: 229 HGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFL 408
+ + P + F +HYF R I+P L K S PL+I M L
Sbjct: 66 YSERRFEPVILTFFLFFQLHYFQRAFIFPL------------LLKGKSKMPLAIMSMGIL 113
Query: 409 FNLLNSYVQAKWVSHY---KNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVL--LRLXG 573
FNLLN Y+Q +W+ + Y + F G L+FF M +N SD ++ LR G
Sbjct: 114 FNLLNGYMQGEWIFYLAPATMYQSDWFTSPYFIIGTLLFFTGMLVNWSSDYIIRHLRKPG 173
Query: 574 EGKGYM 591
+ + Y+
Sbjct: 174 DTRHYL 179
[40][TOP]
>UniRef100_C3QFT7 3-oxo-5-alpha-steroid 4-dehydrogenase n=1 Tax=Bacteroides sp. D1
RepID=C3QFT7_9BACE
Length = 253
Score = 90.5 bits (223), Expect = 9e-17
Identities = 63/186 (33%), Positives = 86/186 (46%), Gaps = 5/186 (2%)
Frame = +1
Query: 49 FNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFP 228
FN L + LIA FI+L F++A YG WG +S LAW LME+P ++
Sbjct: 6 FNLFLGVMSLIALFVFIALYFVKAGYGIFRTASWGVAISNKLAWILMEAPVFVVMCVMWI 65
Query: 229 HGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFL 408
+ + F IHYF R I+P L K S PL+I M L
Sbjct: 66 YSERRFESVIFTFFLFFQIHYFQRAFIFPL------------LLKGKSKMPLAIMSMGVL 113
Query: 409 FNLLNSYVQAKWVSHY---KNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVL--LRLXG 573
FNLLN Y+Q KW+ + Y +G F G L+FF M +N SD ++ LR G
Sbjct: 114 FNLLNGYMQGKWIFYLAPETMYQSGWFTSPWFIIGTLLFFAGMLLNWQSDYIIRHLRKPG 173
Query: 574 EGKGYM 591
+ + Y+
Sbjct: 174 DTRHYL 179
[41][TOP]
>UniRef100_A2DKX3 3-oxo-5-alpha-steroid 4-dehydrogenase family protein n=1
Tax=Trichomonas vaginalis G3 RepID=A2DKX3_TRIVA
Length = 241
Score = 90.5 bits (223), Expect = 9e-17
Identities = 61/171 (35%), Positives = 79/171 (46%), Gaps = 5/171 (2%)
Frame = +1
Query: 94 FISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFPHGKNSSNPKSIILIT 273
FI+L F+ A YGK WGP +S LAW LME P + L+ + +
Sbjct: 9 FIALYFINAGYGKFASRSWGPAISNKLAWILMECPVFFVLCILWFFSERRFKLIYLTFFI 68
Query: 274 PFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWV-- 447
F IHYF R+ I+PF L K S P+ I M FN+ N Y+Q W+
Sbjct: 69 IFQIHYFQRSFIFPF------------LIKGKSYMPILIMVMGATFNVCNGYIQGCWLFY 116
Query: 448 -SHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVL--LRLXGEGKGYM 591
S Y N + F G L+FF M INI SD V+ LR G+ K Y+
Sbjct: 117 TSPEGYYTNEWFYTPQFIIGTLIFFTGMFINIHSDHVIRNLRKPGDTKHYL 167
[42][TOP]
>UniRef100_A2DFR5 3-oxo-5-alpha-steroid 4-dehydrogenase family protein n=1
Tax=Trichomonas vaginalis G3 RepID=A2DFR5_TRIVA
Length = 259
Score = 88.2 bits (217), Expect = 4e-16
Identities = 60/182 (32%), Positives = 82/182 (45%), Gaps = 5/182 (2%)
Frame = +1
Query: 61 LLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFPHGKN 240
+ T+ +I FI+L F+ A YGK WGP + +AW LME P + L+ +
Sbjct: 16 MATMSIIGVFVFIALYFINAGYGKFASRSWGPAIPNKIAWILMECPVFFVLCILWYFSER 75
Query: 241 SSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLL 420
+ F IHYF R+ I+PF L K S P+ I M FN+
Sbjct: 76 RFKLIYLAFFIIFQIHYFQRSFIFPF------------LLKGKSYMPILIMLMGATFNVC 123
Query: 421 NSYVQAKWV---SHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVL--LRLXGEGKG 585
N Y+Q W+ S Y N F G ++FF M INI SD V+ LR G+ K
Sbjct: 124 NGYIQGCWLFYASPEGYYTNEWFCTPQFIIGTIIFFTGMFINIHSDHVIRNLRKPGDTKH 183
Query: 586 YM 591
Y+
Sbjct: 184 YL 185
[43][TOP]
>UniRef100_B9A122 5alpha-reductase type1 n=1 Tax=Rana rugosa RepID=B9A122_RANRU
Length = 255
Score = 87.4 bits (215), Expect = 8e-16
Identities = 56/187 (29%), Positives = 92/187 (49%), Gaps = 1/187 (0%)
Frame = +1
Query: 37 EDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTL 216
E L + L + L+ +F L ++ PYG++ +GP + LAWF+ E P+L +
Sbjct: 8 EARLLDLLSLLMVLMGLLSFALLRCIRVPYGRYASSAFGPPVPVRLAWFIQELPSLVVPV 67
Query: 217 YLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAF 396
Y + P +++L+ F+ HY +RT+I+PF L + PL
Sbjct: 68 YYVSFHPDLPTP-ALLLMGLFICHYMHRTLIFPF------------LIRGGKPTPLVPFA 114
Query: 397 MAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGE 576
+AF+F N Y+Q+ ++ + + G + F GL +FF M INI+SD +L L
Sbjct: 115 LAFIFCCYNGYLQSSYLCKHSTFHPGWTYDPRFIAGLALFFCGMSINIYSDHILRNLRKP 174
Query: 577 GK-GYMI 594
G+ GY I
Sbjct: 175 GESGYKI 181
[44][TOP]
>UniRef100_Q6DF23 Steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5
alpha-steroid delta 4-dehydrogenase alpha 1) n=1
Tax=Xenopus (Silurana) tropicalis RepID=Q6DF23_XENTR
Length = 257
Score = 87.0 bits (214), Expect = 1e-15
Identities = 54/187 (28%), Positives = 94/187 (50%), Gaps = 1/187 (0%)
Frame = +1
Query: 37 EDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTL 216
E L N + + L+ +++SL +++ PYG++ +GP + LAWF+ E P+L +L
Sbjct: 10 EAQLLNLLAMFMALMGLVSYVSLQYIRMPYGRYADSAFGPPVPVRLAWFVQEVPSLSVSL 69
Query: 217 YLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAF 396
+ + S +L+ F+ HY RT+I+PF L + P +
Sbjct: 70 FFYLRQTEFSIANQ-VLMGAFICHYTQRTLIFPF------------LIRGGKPTPFASFA 116
Query: 397 MAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGE 576
+AF+F N Y+Q+ ++ + Y + F G+++FF M INI+SD++L L
Sbjct: 117 LAFIFCCYNGYLQSSYLCSHAAYASDWIHDPRFITGIMLFFCGMFINIYSDRILRNLRKP 176
Query: 577 GK-GYMI 594
G+ GY I
Sbjct: 177 GEMGYKI 183
[45][TOP]
>UniRef100_B7BCT4 Putative uncharacterized protein n=1 Tax=Parabacteroides johnsonii
DSM 18315 RepID=B7BCT4_9PORP
Length = 253
Score = 87.0 bits (214), Expect = 1e-15
Identities = 57/186 (30%), Positives = 81/186 (43%), Gaps = 5/186 (2%)
Frame = +1
Query: 49 FNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFP 228
F L+ + IA FI+L F++A YG WG + +AW ME+P L+
Sbjct: 6 FTLFLIVMAAIAAIVFIALYFVEAGYGMLFDKKWGFPIPNKIAWICMEAPVFIVMFLLWN 65
Query: 229 HGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFL 408
+ ++ F +HYF R+ I+P L K S P I M
Sbjct: 66 GSERQFEAVPFLIFLFFELHYFQRSFIFPL------------LIKGKSKMPAGIMLMGIT 113
Query: 409 FNLLNSYVQAKWVSHYKNYDNGLCFW---GVFFGGLLVFFVXMGINIWSDKVL--LRLXG 573
FNLLN Y+Q +W+ H D W F G ++FF M INI SD ++ LR G
Sbjct: 114 FNLLNGYMQGEWIFHLAPQDMYTESWLYSPQFITGTILFFTGMAINIQSDHIVRHLRKPG 173
Query: 574 EGKGYM 591
+ Y+
Sbjct: 174 DTNHYL 179
[46][TOP]
>UniRef100_A4GI04 Putative uncharacterized protein n=1 Tax=uncultured marine
bacterium EB0_39H12 RepID=A4GI04_9BACT
Length = 252
Score = 85.5 bits (210), Expect = 3e-15
Identities = 55/187 (29%), Positives = 91/187 (48%), Gaps = 1/187 (0%)
Frame = +1
Query: 37 EDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTL 216
ED+ +++ L F +A FI L + APYG+H + G LS W +MESPA++ L
Sbjct: 4 EDTYYSFLFLWAF-VALIVFIVLFYKDAPYGRHLKQGSSFTLSSRAGWIIMESPAVFGIL 62
Query: 217 YLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAF 396
+ +L +L+HY +RT ++P R L ++ + +
Sbjct: 63 IFLYMFYQTIGITETLLCCIWLLHYIHRTFVWPLRAKLRGKQ-----------MGVGVMS 111
Query: 397 MAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRL-XG 573
MA LFN++N +Q W+ Y + +F G+++F + M INI SD +L+ L
Sbjct: 112 MALLFNVVNITLQCIWIFILGEYTDQWLLSPLFIVGIIIFLLGMLINIKSDNILMNLRKS 171
Query: 574 EGKGYMI 594
G+GY +
Sbjct: 172 GGRGYHV 178
[47][TOP]
>UniRef100_C4LVC4 Steroid 5-alpha reductase, putative n=1 Tax=Entamoeba histolytica
HM-1:IMSS RepID=C4LVC4_ENTHI
Length = 252
Score = 85.5 bits (210), Expect = 3e-15
Identities = 56/183 (30%), Positives = 88/183 (48%), Gaps = 2/183 (1%)
Frame = +1
Query: 40 DSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLY 219
+S++ LL + ++ F+ L ++ A YG WG ++ + W +ME ++ L
Sbjct: 4 ESIYYLFLLVMVILGFIVFVLLHYVTAGYGMFQTDKWGVTINNRIGWCIMEIVSMIGMLI 63
Query: 220 LFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFM 399
+ + I LI F+IHYF R+II+P R+ P+ I M
Sbjct: 64 FYVYSSVDEIVPIISLIL-FVIHYFRRSIIFPLRM------------SKGGKMPIIIMLM 110
Query: 400 AFLFNLLNSYVQAKWVS--HYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXG 573
+FNL N YVQA W+ H +Y G + G+LVFFV M IN+ SD+++ L
Sbjct: 111 GMVFNLCNCYVQAGWLFLYHPPHYYLGWFNTPQCYFGVLVFFVGMAINVHSDEIIRNLRK 170
Query: 574 EGK 582
EG+
Sbjct: 171 EGE 173
[48][TOP]
>UniRef100_A7AKP3 Putative uncharacterized protein n=1 Tax=Parabacteroides merdae
ATCC 43184 RepID=A7AKP3_9PORP
Length = 253
Score = 85.1 bits (209), Expect = 4e-15
Identities = 56/186 (30%), Positives = 81/186 (43%), Gaps = 5/186 (2%)
Frame = +1
Query: 49 FNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFP 228
F L+ + IA FI+L F++A YG WG + +AW ME+P L+
Sbjct: 6 FTLFLIVMAAIAAIVFIALYFVEAGYGMLFDKKWGLPIPNKIAWICMEAPVFIVMFLLWN 65
Query: 229 HGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFL 408
+ ++ F +HYF R+ I+P L K S P I M
Sbjct: 66 GSERQFETVPFLIFLFFELHYFQRSFIFPL------------LIKGKSKMPAGIMLMGIT 113
Query: 409 FNLLNSYVQAKWVSHYKNYDNGLCFW---GVFFGGLLVFFVXMGINIWSDKVL--LRLXG 573
FNLLN Y+Q +W+ + D W F G ++FF M INI SD ++ LR G
Sbjct: 114 FNLLNGYMQGEWIFYLAPQDMYTKSWLHSPQFIVGTILFFTGMAINIQSDHIVRHLRKPG 173
Query: 574 EGKGYM 591
+ Y+
Sbjct: 174 DTNHYL 179
[49][TOP]
>UniRef100_A5D8N5 LOC100049757 protein n=1 Tax=Xenopus laevis RepID=A5D8N5_XENLA
Length = 257
Score = 84.7 bits (208), Expect = 5e-15
Identities = 50/187 (26%), Positives = 93/187 (49%), Gaps = 1/187 (0%)
Frame = +1
Query: 37 EDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTL 216
E N + + L+ ++ L +++ PYG++ +GP + LAWF+ E P+L+ +
Sbjct: 10 ERQFLNLLAMFMALMGLVSYAMLQYIRMPYGRYATSVFGPPVPVRLAWFVQEVPSLFIPV 69
Query: 217 YLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAF 396
+ + ++ + +L+ + HY RT+++PF L + P +
Sbjct: 70 FFYLR-QSELGIANQVLMGALICHYIQRTLVFPF------------LIRGGKPTPFASFA 116
Query: 397 MAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGE 576
+AF+F N Y+Q+ ++ HY Y + F G+++FF M INI+SD++L L
Sbjct: 117 LAFIFCCYNGYMQSSYLCHYAFYASDWIHDPCFITGIMLFFCGMFINIYSDRILRNLRKP 176
Query: 577 GK-GYMI 594
G+ GY I
Sbjct: 177 GETGYKI 183
[50][TOP]
>UniRef100_A2F2U6 3-oxo-5-alpha-steroid 4-dehydrogenase family protein n=1
Tax=Trichomonas vaginalis G3 RepID=A2F2U6_TRIVA
Length = 270
Score = 84.3 bits (207), Expect = 6e-15
Identities = 57/176 (32%), Positives = 76/176 (43%), Gaps = 3/176 (1%)
Frame = +1
Query: 61 LLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFPHGKN 240
+ T+ +I FI+L F+ A YGK WGP + LAW LME P L+ +
Sbjct: 16 MATMSIIGVFVFIALYFINAGYGKFASRSWGPAIPNKLAWILMECPVFIVLCILWYFSER 75
Query: 241 SSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLL 420
+ F IHYF R+ I+PF L K S P+ I M FN+
Sbjct: 76 RFQLIYLTFFIIFQIHYFQRSFIFPF------------LLKGKSYMPILIMLMGATFNVC 123
Query: 421 NSYVQAKWVSHYK---NYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEG 579
N Y+Q W+ + Y N F G ++FF M INI SD V+ L G
Sbjct: 124 NGYIQGCWLFYTAPEGYYTNEWFCTPQFIIGTIIFFTGMFINIHSDHVIRNLRKPG 179
[51][TOP]
>UniRef100_B7GEG4 De-etiolated 2 like protein (Fragment) n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7GEG4_PHATR
Length = 242
Score = 82.4 bits (202), Expect = 2e-14
Identities = 58/178 (32%), Positives = 82/178 (46%), Gaps = 12/178 (6%)
Frame = +1
Query: 97 ISLTFLQAPYGKHHRPGW--GPNLSPPLAWFLMESPAL-WFTLYL--------FPHGKNS 243
+ L + +PYGK R W GP+L WFL E+P L W + L PH
Sbjct: 1 VLLFVIPSPYGKTLRTDWYLGPHLPARACWFLFETPNLIWCAVGLGQRMASRQSPHAAPG 60
Query: 244 SNP-KSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLL 420
P + IL+ F +HY RTI+YP R+ TT+ + P +A +A F +
Sbjct: 61 WPPWPNFILLVLFTLHYTQRTILYPLRM--TTQSQP---------IPALVAALAIFFTTI 109
Query: 421 NSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGKGYMI 594
N Y+Q + + + G VF G+ +F IN+ SD L RL +GKGY I
Sbjct: 110 NGYLQVSGLLEFHHLPPGYGTNPVFGAGVCLFLYGASINLQSDATLRRLKAQGKGYQI 167
[52][TOP]
>UniRef100_A5HL61 Steroid-5-alpha-reductase alpha polypeptide 1 (Fragment) n=1
Tax=Oryzias latipes RepID=A5HL61_ORYLA
Length = 288
Score = 82.0 bits (201), Expect = 3e-14
Identities = 62/183 (33%), Positives = 88/183 (48%), Gaps = 4/183 (2%)
Frame = +1
Query: 58 ALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFPHG- 234
A L LF+ A T +SL F PYG++ +G ++ LAW + E P+L LYL
Sbjct: 47 AYLMLFM-AVCTLVSLRFENVPYGRYASSKYGFPVNVKLAWCVQELPSLLIPLYLTVSAT 105
Query: 235 --KNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFL 408
K S P + LI F+ HY R IIYPF L + G P +A L
Sbjct: 106 SVKTSVLPNQL-LIAMFVCHYIQRAIIYPF------------LIRGGKGTPFVSFALALL 152
Query: 409 FNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK-G 585
F L N Y+Q +++SHY +Y +F G +++ V +N+ SD +L L G+ G
Sbjct: 153 FCLYNGYMQVRYLSHYADYRPHWVTHPLFILGSVLWLVGWLLNLHSDHILRNLRKPGETG 212
Query: 586 YMI 594
Y I
Sbjct: 213 YKI 215
[53][TOP]
>UniRef100_C8PQD5 3-oxo-5-alpha-steroid 4-dehydrogenase 1 n=1 Tax=Treponema vincentii
ATCC 35580 RepID=C8PQD5_9SPIO
Length = 243
Score = 82.0 bits (201), Expect = 3e-14
Identities = 60/181 (33%), Positives = 83/181 (45%), Gaps = 5/181 (2%)
Frame = +1
Query: 61 LLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFPHGKN 240
+L L LI F +L F+ A YGK WG + + AW LME P L + L
Sbjct: 1 MLVLGLIC---FFALYFIPAGYGKLIDKKWGFSFNNKAAWMLMECPTLIVMISLLSILDY 57
Query: 241 SSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLL 420
+ P I+L++ FL HY RT+I+P L K S PLSI M LFN +
Sbjct: 58 AHKPVRIVLVSFFLAHYIQRTLIFPM------------LLKGNSKMPLSIVSMGMLFNTI 105
Query: 421 NSYVQAKWVSHYKNYDNGLCFWGV---FFGGLLVFFVXMGINIWSDKVL--LRLXGEGKG 585
N+++ W+ ++ + W F G +F M INI SD + LR G+ K
Sbjct: 106 NAFLIGLWIFYFSPAEMYSVRWFADPRFIVGAALFCAGMFINIQSDSYIRSLRSNGDSKH 165
Query: 586 Y 588
Y
Sbjct: 166 Y 166
[54][TOP]
>UniRef100_C8PMQ9 3-oxo-5-alpha-steroid 4-dehydrogenase 1 n=1 Tax=Treponema vincentii
ATCC 35580 RepID=C8PMQ9_9SPIO
Length = 255
Score = 82.0 bits (201), Expect = 3e-14
Identities = 59/170 (34%), Positives = 79/170 (46%), Gaps = 5/170 (2%)
Frame = +1
Query: 94 FISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFPHGKNSSNPKSIILIT 273
F +L F+ A YGK WG + + AW LME P L L L + P I+L++
Sbjct: 21 FFALYFIPAGYGKLIDKKWGFSFNNKAAWMLMECPTLIVMLSLLFTLDYAHKPVRIVLVS 80
Query: 274 PFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSH 453
FL HY RT+I+P L K S PLSI M LFN +N+++ W+ +
Sbjct: 81 FFLAHYIQRTLIFPM------------LLKGNSKMPLSIVSMGMLFNTINAFLIGLWIFY 128
Query: 454 Y---KNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVL--LRLXGEGKGY 588
+ + Y G F G + F M INI SD + LR GE K Y
Sbjct: 129 FSPAEMYSVGWFGDPRFILGAVFFCAGMFINIQSDSYIRSLRTHGESKHY 178
[55][TOP]
>UniRef100_Q08C19 Steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5
alpha-steroid delta 4-dehydrogenase alpha 1) n=1
Tax=Danio rerio RepID=Q08C19_DANRE
Length = 265
Score = 81.3 bits (199), Expect = 5e-14
Identities = 59/198 (29%), Positives = 100/198 (50%), Gaps = 8/198 (4%)
Frame = +1
Query: 25 FFQKEDSLF-----NYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLM 189
F +E+ L+ +Y ++ + LI TF++L F PYG++ +G ++ LAWF+
Sbjct: 9 FSSEEEELYVLDCLSYLMMAMALI---TFVALLFEHVPYGRYASSRFGFPVNVKLAWFVQ 65
Query: 190 ESPA--LWFTLYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSK 363
E P+ L +L L+ + + +L+ F+ HY R++IYPF + R KS+
Sbjct: 66 ELPSFLLPLSLALWSSSSKIIHLPNQLLLLMFVCHYMQRSLIYPFLI----RGGKST--- 118
Query: 364 TPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIW 543
P +AF+F + N Y+Q +++SHY +Y F G ++F+ IN+
Sbjct: 119 -----PFISLVLAFVFCIYNGYLQGRYLSHYADYPADWVTHPCFIIGSCMWFLGWIINMH 173
Query: 544 SDKVLLRLXGEGK-GYMI 594
SD +L L G+ GY I
Sbjct: 174 SDHILRNLRKPGETGYKI 191
[56][TOP]
>UniRef100_Q73J79 3-oxo-5-alpha-steroid 4-dehydrogenase family protein n=1
Tax=Treponema denticola RepID=Q73J79_TREDE
Length = 257
Score = 80.9 bits (198), Expect = 7e-14
Identities = 58/181 (32%), Positives = 80/181 (44%), Gaps = 3/181 (1%)
Frame = +1
Query: 46 LFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLF 225
+FN + LF + F+ L F+ A YGK WG + + +AWFLME P L + L
Sbjct: 7 IFNITQIVLFGVGLICFVVLFFVPAGYGKMINKKWGFSFNNKIAWFLMEVPTLITMIVLM 66
Query: 226 PHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAF 405
N II+ F++HY R I+PF L K S P+ I M
Sbjct: 67 CVWAKPENFVRIIIGLFFVLHYAQRVFIFPF------------LLKGKSKMPILIVLMGI 114
Query: 406 LFNLLNSYVQAKW---VSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGE 576
FN +N+++ W +S Y + F G LVF + M INI SDK + L
Sbjct: 115 TFNTINAFLIGAWLFYLSPKTMYPISWLYDPRFIIGALVFLLGMAINIDSDKYIRSLRKP 174
Query: 577 G 579
G
Sbjct: 175 G 175
[57][TOP]
>UniRef100_B0EQD7 3-oxo-5-alpha-steroid 4-dehydrogenase, putative n=1 Tax=Entamoeba
dispar SAW760 RepID=B0EQD7_ENTDI
Length = 252
Score = 80.9 bits (198), Expect = 7e-14
Identities = 54/188 (28%), Positives = 88/188 (46%), Gaps = 7/188 (3%)
Frame = +1
Query: 40 DSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLY 219
++++ LL + +I FI L ++ YG WG ++ + W +ME ++ +
Sbjct: 4 ENIYYLFLLIMLIIGFIVFILLHYITVGYGMFQNNKWGLTINNKIGWCVMEIVSMIGIII 63
Query: 220 LFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFM 399
+ + + I LI F+IHYF R+II+P R+ P+ I M
Sbjct: 64 FYIYSSMNEIIPMISLIL-FIIHYFRRSIIFPLRI------------SKGGKMPIIIMLM 110
Query: 400 AFLFNLLNSYVQAKWVSHY-------KNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVL 558
LFNL N Y QA W+ Y + ++ C++ GLL FF+ M INI SD+++
Sbjct: 111 GMLFNLCNCYAQAGWLFFYHPPYYYLRWFNTPQCYF-----GLLFFFIGMVINIHSDEII 165
Query: 559 LRLXGEGK 582
L EG+
Sbjct: 166 RSLRKEGE 173
[58][TOP]
>UniRef100_A5PMI4 Novel protein similar to vertebrate steroid-5-alpha-reductase,
alpha polypeptide 1 (3-oxo-5 alpha-steroid delta
4-dehydrogenase alpha 1) (SRD5A1) n=1 Tax=Danio rerio
RepID=A5PMI4_DANRE
Length = 265
Score = 80.5 bits (197), Expect = 9e-14
Identities = 58/198 (29%), Positives = 99/198 (50%), Gaps = 8/198 (4%)
Frame = +1
Query: 25 FFQKEDSLF-----NYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLM 189
F +E+ L+ +Y ++ + LI TF++L F PYG++ +G ++ LAWF+
Sbjct: 9 FSSEEEELYVLDCLSYLMMAMALI---TFVALLFEHVPYGRYASSRFGFPVNVKLAWFVQ 65
Query: 190 ESPALWF--TLYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSK 363
E P+ +L L+ + + +L+ F+ HY R++IYPF + R KS+
Sbjct: 66 ELPSFLLPSSLALWSSSSKIIHLPNQLLLLMFVCHYMQRSLIYPFLI----RGGKST--- 118
Query: 364 TPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIW 543
P +AF+F + N Y+Q +++SHY +Y F G ++F+ IN+
Sbjct: 119 -----PFISLVLAFVFCIYNGYLQGRYLSHYADYPADWVTHPCFIIGSCMWFLGWIINMH 173
Query: 544 SDKVLLRLXGEGK-GYMI 594
SD +L L G+ GY I
Sbjct: 174 SDHILRNLRKPGETGYKI 191
[59][TOP]
>UniRef100_A7RP43 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
RepID=A7RP43_NEMVE
Length = 231
Score = 79.7 bits (195), Expect = 2e-13
Identities = 56/172 (32%), Positives = 81/172 (47%), Gaps = 8/172 (4%)
Frame = +1
Query: 103 LTFLQAPYGKHH------RPGWGPNLSPPLAWFLMESPALWFTLY-LFPHGKNSSNPKSI 261
L L+A YG++ R GWG N AWF E+P L +Y + G+ NP S+
Sbjct: 1 LQCLKAEYGRYFNSKSEARWGWGVNAK--FAWFTQETPMLALPVYYMLSTGRLGWNPNSV 58
Query: 262 ILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAK 441
+L + +IHYF R IY F+L K P+S+ M ++ L N Y+ +
Sbjct: 59 LL-SFIIIHYFRRVFIYSFQL------------KGGKPTPISLWLMCIVYTLTNGYIHGR 105
Query: 442 WVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK-GYMI 594
+ + Y YD F G L+FF + +NI SD +L L G+ GY I
Sbjct: 106 YFTEYAKYDKKWLSDPRFLCGTLMFFTGLFLNIQSDNILTSLRKPGEVGYKI 157
[60][TOP]
>UniRef100_B0NUH3 Putative uncharacterized protein n=1 Tax=Bacteroides stercoris ATCC
43183 RepID=B0NUH3_BACSE
Length = 256
Score = 79.3 bits (194), Expect = 2e-13
Identities = 57/188 (30%), Positives = 89/188 (47%), Gaps = 7/188 (3%)
Frame = +1
Query: 49 FNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFP 228
F+ L + +IA FI+L F++A YG WG ++S AW LME+P +L+
Sbjct: 6 FHLFLGVMCVIALFVFIALYFVKAGYGMFRTASWGYSISNKAAWVLMEAPVFIVMFWLWG 65
Query: 229 HGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFL 408
+ F +HYF R+ I+PF L K S P++I M +
Sbjct: 66 RSGAGFAVPVYLFFLLFQLHYFQRSFIFPF------------LLKGKSRMPVTIMMMGIV 113
Query: 409 FNLLNSYVQAKWVSHYKN---YDNGLCFW--GVFFGGLLVFFVXMGINIWSDKVL--LRL 567
FN+LN +QA + ++ + Y G + + GLL+FF M IN+ +D V+ LR
Sbjct: 114 FNVLNGMMQAGGLFYFASEGMYSGGWTYLLKTHAWSGLLLFFAGMLINLHADHVIRHLRK 173
Query: 568 XGEGKGYM 591
G+ Y+
Sbjct: 174 PGDTNHYL 181
[61][TOP]
>UniRef100_UPI00016E946B UPI00016E946B related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E946B
Length = 267
Score = 78.2 bits (191), Expect = 5e-13
Identities = 54/195 (27%), Positives = 92/195 (47%), Gaps = 5/195 (2%)
Frame = +1
Query: 25 FFQKEDSLFNYALLTLFLI--APPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESP 198
F +++ L+ L F++ A F++L F PYG++ +G ++ +AWF+ E P
Sbjct: 9 FSSEKEELYILDCLAYFMVFMAACCFVTLLFENVPYGRYSTSKYGFPVNAKVAWFIQELP 68
Query: 199 ALW--FTLYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPS 372
A F+L ++ +S + +LI + HY R +IYPF L +
Sbjct: 69 AFLVPFSLLVWTSSARTSLLPNQLLIAMYFCHYVQRALIYPF------------LIRGGK 116
Query: 373 GFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDK 552
P +AF+F + N Y+Q +++SHY Y F G +++F +N+ SD
Sbjct: 117 PTPFVSFALAFVFCVYNGYMQIRYLSHYAVYPAHWFTHPCFITGSVLWFTGWLVNVHSDH 176
Query: 553 VLLRLXGEGK-GYMI 594
+L L G+ GY I
Sbjct: 177 ILRNLRQPGESGYKI 191
[62][TOP]
>UniRef100_B3JQR4 Putative uncharacterized protein n=1 Tax=Bacteroides coprocola DSM
17136 RepID=B3JQR4_9BACE
Length = 257
Score = 78.2 bits (191), Expect = 5e-13
Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 8/189 (4%)
Frame = +1
Query: 49 FNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFP 228
+ + L + + F++L F++A YG WG +L LAW LME+PA L+ +
Sbjct: 6 YQFLLYAMSVAGAVVFVALYFVRAGYGMFRTSSWGISLPNKLAWMLMEAPAFVVMLWGWL 65
Query: 229 HGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFL 408
+ FL+HYF R+ ++P L + S P++I M +
Sbjct: 66 SSDIDVFAPQFVFACLFLLHYFQRSFVFPL------------LMRGKSRMPVAIVAMGIV 113
Query: 409 FNLLNSYVQAKWVSHYKN----YDNGLCFWGVFFG--GLLVFFVXMGINIWSDKVL--LR 564
FN+LN + Y + Y G +W F GL +F M IN+ SD V+ LR
Sbjct: 114 FNILNGMLLITSFFSYPSAEDLYAEGCGYWMHSFPWIGLALFIAGMSINLHSDYVIRHLR 173
Query: 565 LXGEGKGYM 591
G+ K Y+
Sbjct: 174 KSGDTKHYL 182
[63][TOP]
>UniRef100_UPI00016E946A UPI00016E946A related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E946A
Length = 254
Score = 77.4 bits (189), Expect = 8e-13
Identities = 51/177 (28%), Positives = 84/177 (47%), Gaps = 3/177 (1%)
Frame = +1
Query: 73 FLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALW--FTLYLFPHGKNSS 246
F +A F++L F PYG++ +G ++ +AWF+ E PA F+L ++ +S
Sbjct: 14 FFMAACCFVTLLFENVPYGRYSTSKYGFPVNAKVAWFIQELPAFLVPFSLLVWTSSARTS 73
Query: 247 NPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNS 426
+ +LI + HY R +IYPF L + P +AF+F + N
Sbjct: 74 LLPNQLLIAMYFCHYVQRALIYPF------------LIRGGKPTPFVSFALAFVFCVYNG 121
Query: 427 YVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK-GYMI 594
Y+Q +++SHY Y F G +++F +N+ SD +L L G+ GY I
Sbjct: 122 YMQIRYLSHYAVYPAHWFTHPCFITGSVLWFTGWLVNVHSDHILRNLRQPGESGYKI 178
[64][TOP]
>UniRef100_B7AD31 Putative uncharacterized protein n=1 Tax=Bacteroides eggerthii DSM
20697 RepID=B7AD31_9BACE
Length = 256
Score = 77.0 bits (188), Expect = 1e-12
Identities = 51/173 (29%), Positives = 81/173 (46%), Gaps = 7/173 (4%)
Frame = +1
Query: 94 FISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFPHGKNSSNPKSIILIT 273
FI+L F++A YG WG +++ LAW LME+P +L+ + +
Sbjct: 21 FIALYFIKAGYGMFRTASWGYSINNKLAWVLMEAPVFIVMFWLWGRSGVGFSVPVYLFFL 80
Query: 274 PFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSH 453
F +HYF R+ ++PF L K S P++I M +FN+LN +QA + +
Sbjct: 81 LFQLHYFQRSFVFPF------------LLKGKSRMPVAIMAMGIVFNVLNGMMQAGGLFY 128
Query: 454 YKNYDNGLCFWGVFFG-----GLLVFFVXMGINIWSDKVL--LRLXGEGKGYM 591
+ W G+L+FF M IN+ SD V+ LR G+ + Y+
Sbjct: 129 FAPEGLYAGGWAYLLKPHALLGVLLFFAGMFINLHSDHVIRHLRKPGDTRHYL 181
[65][TOP]
>UniRef100_UPI00016E9239 UPI00016E9239 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E9239
Length = 217
Score = 76.6 bits (187), Expect = 1e-12
Identities = 53/192 (27%), Positives = 91/192 (47%), Gaps = 5/192 (2%)
Frame = +1
Query: 34 KEDSLFNYALLTLFLI--APPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALW 207
+++ L+ L F++ A F++L F PYG++ +G ++ +AWF+ E PA
Sbjct: 2 EKEELYILDCLAYFMVFMAACCFVTLLFENVPYGRYSTSKYGFPVNAKVAWFIQELPAFL 61
Query: 208 --FTLYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFP 381
F+L ++ +S + +LI + HY R +IYPF L + P
Sbjct: 62 VPFSLLVWTSSARTSLLPNQLLIAMYFCHYVQRALIYPF------------LIRGGKPTP 109
Query: 382 LSIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLL 561
+AF+F + N Y+Q +++SHY Y F G +++F +N+ SD +L
Sbjct: 110 FVSFALAFVFCVYNGYMQIRYLSHYAVYPAHWFTHPCFITGSVLWFTGWLVNVHSDHILR 169
Query: 562 RLXGEGK-GYMI 594
L G+ GY I
Sbjct: 170 NLRQPGESGYKI 181
[66][TOP]
>UniRef100_B5XCB5 3-oxo-5-alpha-steroid 4-dehydrogenase 2 n=1 Tax=Salmo salar
RepID=B5XCB5_SALSA
Length = 253
Score = 76.6 bits (187), Expect = 1e-12
Identities = 53/161 (32%), Positives = 76/161 (47%), Gaps = 2/161 (1%)
Frame = +1
Query: 106 TFLQAPYGKHHRPGWGPNLSPP--LAWFLMESPALWFTLYLFPHGKNSSNPKSIILITPF 279
T Q PYG++ P + P LAWFL E P+ + L + +L+ F
Sbjct: 27 TRFQTPYGRYVTSDGTPGRTCPAKLAWFLQELPSFLVPMLLLLSTDTQPSLGKDLLLWTF 86
Query: 280 LIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYK 459
+HYF RT IY L T+ + S PL I F A +F +N ++Q ++ H
Sbjct: 87 CLHYFQRTFIYS----LLTKGRPS---------PLYIVFSAVVFCSVNGFLQGHYMLHCA 133
Query: 460 NYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK 582
YD+ + GLL+FF+ M INI SD +LL L G+
Sbjct: 134 TYDDAWQTDIRLYTGLLMFFLGMAINIHSDHILLNLRKPGE 174
[67][TOP]
>UniRef100_C9K4Z4 5alpha-reductase I n=1 Tax=Branchiostoma belcheri
RepID=C9K4Z4_BRABE
Length = 263
Score = 76.3 bits (186), Expect = 2e-12
Identities = 58/191 (30%), Positives = 91/191 (47%), Gaps = 5/191 (2%)
Frame = +1
Query: 37 EDSLFNYALLTLFLIAPPTFISLTFLQ-APYGKHHRPGWGPNLSPP-LAWFLMESPALWF 210
E +L +Y + ++ PTF+ L F+ A YG++ P P +AW + E PA
Sbjct: 11 ELALLDYLAYGMIGVSIPTFLLLMFVTTALYGRNSTQFIVPGFLPARVAWLVQELPAFGV 70
Query: 211 T--LYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPL 384
L L + + +L+ +++HYFNR++I+P L + PL
Sbjct: 71 PCLLLLATSADRLAYLPNRVLLAMYMVHYFNRSLIFPM------------LIRGGKPTPL 118
Query: 385 SIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLR 564
+A +F + N Y+QA+++S Y Y +G F G+L+F M INI SD VL
Sbjct: 119 VPFLLALMFCVYNGYLQARYLSQYAQYPDGWLMDPRFIVGILMFAAGMAINIHSDHVLRS 178
Query: 565 LXGEGK-GYMI 594
L G+ GY I
Sbjct: 179 LRKPGETGYKI 189
[68][TOP]
>UniRef100_UPI00017B2649 UPI00017B2649 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B2649
Length = 261
Score = 75.9 bits (185), Expect = 2e-12
Identities = 57/160 (35%), Positives = 72/160 (45%), Gaps = 4/160 (2%)
Frame = +1
Query: 115 QAPYGKHHRPGWGPNLSP-PLAWFLMESPALWFTLYLFPHGKNSSNPKSIILITPFLIHY 291
Q YG+H RP P PLAWFL E PA L L +S +L+ F+ HY
Sbjct: 35 QLSYGRHMRPTPLLRTVPAPLAWFLQEMPAFLIPLLLTLTPHQASGTGKRLLLGTFVTHY 94
Query: 292 FNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYDN 471
F RT IY FLT R FPL++ F L+ ++Q ++ H YD
Sbjct: 95 FQRTFIYS---FLTRGRP----------FPLNVMVAGAFFCSLSGFLQGHYLLHCAQYDQ 141
Query: 472 GLCFWGVFF---GGLLVFFVXMGINIWSDKVLLRLXGEGK 582
W F GLL+F+ M INI SD VL L G+
Sbjct: 142 ---HWTAGFRCRTGLLLFYTGMAINIHSDSVLRNLREPGE 178
[69][TOP]
>UniRef100_Q20344 Protein F42F12.3, partially confirmed by transcript evidence n=1
Tax=Caenorhabditis elegans RepID=Q20344_CAEEL
Length = 243
Score = 75.9 bits (185), Expect = 2e-12
Identities = 58/163 (35%), Positives = 82/163 (50%), Gaps = 2/163 (1%)
Frame = +1
Query: 112 LQAPYGKH-HRPGWGPNLSPPLAWFLMESPALWFTLYLFPHGKNSSNPKSIILITPFLIH 288
L A YG++ ++ WG N P LAWF+ ESPA + Y G +S+ IL FL+H
Sbjct: 27 LTAGYGRYTNQAQWGIN--PKLAWFIQESPAFFIPFYFLFGGLSSTGR---ILNCIFLVH 81
Query: 289 YFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYD 468
YF R +IYPFR+ TT+ PL I A F N +Q W S+Y+ +
Sbjct: 82 YFYRALIYPFRIRSTTKS------------PLLIVAAAVAFCTYNGTLQGVWNSYYQ-LE 128
Query: 469 NGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK-GYMI 594
L + + G +++F M IN SD +L+ L G+ GY I
Sbjct: 129 EELTYRHLI--GSILYFSGMFINHKSDNILMTLRKPGETGYKI 169
[70][TOP]
>UniRef100_C7T2J7 Steroid 5 alpha-reductase 1 n=1 Tax=Mesocricetus auratus
RepID=C7T2J7_MESAU
Length = 255
Score = 75.5 bits (184), Expect = 3e-12
Identities = 54/176 (30%), Positives = 82/176 (46%), Gaps = 3/176 (1%)
Frame = +1
Query: 76 LIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLF--PHGKNSSN 249
L+A + LT + +PYG++ G L AWFL E P++ + LY + P +
Sbjct: 18 LLAFVVLVFLTLVGSPYGRYSAQHPGLQLPARPAWFLQELPSMAWPLYEYTRPAAARLGS 77
Query: 250 PKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSY 429
+ +L+ FLIHY RT+I+P L + P+ A LF N Y
Sbjct: 78 MPNRVLLAMFLIHYVQRTLIFPV------------LIRGGKPTPMFSFAAAVLFCTFNGY 125
Query: 430 VQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK-GYMI 594
+Q++++S + Y F G ++FV M INI SD +L L G+ GY I
Sbjct: 126 LQSRYLSQFAVYTEDWVAHPCFLTGFTMWFVGMVINIHSDHILRNLRKPGETGYKI 181
[71][TOP]
>UniRef100_Q4RQ00 Chromosome 17 SCAF15006, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4RQ00_TETNG
Length = 224
Score = 74.7 bits (182), Expect = 5e-12
Identities = 56/157 (35%), Positives = 71/157 (45%), Gaps = 4/157 (2%)
Frame = +1
Query: 124 YGKHHRPGWGPNLSP-PLAWFLMESPALWFTLYLFPHGKNSSNPKSIILITPFLIHYFNR 300
YG+H RP P PLAWFL E PA L L +S +L+ F+ HYF R
Sbjct: 1 YGRHMRPTPLLRTVPAPLAWFLQEMPAFLIPLLLTLTPHQASGTGKRLLLGTFVTHYFQR 60
Query: 301 TIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLC 480
T IY FLT R FPL++ F L+ ++Q ++ H YD
Sbjct: 61 TFIYS---FLTRGRP----------FPLNVMVAGAFFCSLSGFLQGHYLLHCAQYDQ--- 104
Query: 481 FWGVFF---GGLLVFFVXMGINIWSDKVLLRLXGEGK 582
W F GLL+F+ M INI SD VL L G+
Sbjct: 105 HWTAGFRCRTGLLLFYTGMAINIHSDSVLRNLREPGE 141
[72][TOP]
>UniRef100_Q8BUR8 Putative uncharacterized protein n=1 Tax=Mus musculus
RepID=Q8BUR8_MOUSE
Length = 217
Score = 74.7 bits (182), Expect = 5e-12
Identities = 53/170 (31%), Positives = 82/170 (48%), Gaps = 3/170 (1%)
Frame = +1
Query: 94 FISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLY--LFPHGKNSSNPKSIIL 267
F+ L + + YG++ G + AWFL E P++ + LY + P N + +L
Sbjct: 24 FVGLQMVGSSYGRYSSQWSGRRVPARPAWFLQELPSMAWPLYECIRPAAARLGNLPNRVL 83
Query: 268 ITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWV 447
+ FLIHY RT+++P + R K +L L +AFLF LN Y+Q++++
Sbjct: 84 LAMFLIHYVQRTLVFPVLI----RGGKPTL--------LFTFVLAFLFCTLNGYLQSRYL 131
Query: 448 SHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK-GYMI 594
S + Y F G ++ V M INI SD +L L G+ GY I
Sbjct: 132 SQFAVYAEDWVTHPCFLTGFALWLVGMVINIHSDHILRNLRKPGETGYKI 181
[73][TOP]
>UniRef100_Q68FF9 3-oxo-5-alpha-steroid 4-dehydrogenase 1 n=1 Tax=Mus musculus
RepID=S5A1_MOUSE
Length = 255
Score = 74.7 bits (182), Expect = 5e-12
Identities = 53/170 (31%), Positives = 82/170 (48%), Gaps = 3/170 (1%)
Frame = +1
Query: 94 FISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLY--LFPHGKNSSNPKSIIL 267
F+ L + + YG++ G + AWFL E P++ + LY + P N + +L
Sbjct: 24 FVGLQMVGSSYGRYSSQWSGRRVPARPAWFLQELPSMAWPLYECIRPAAARLGNLPNRVL 83
Query: 268 ITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWV 447
+ FLIHY RT+++P + R K +L L +AFLF LN Y+Q++++
Sbjct: 84 LAMFLIHYVQRTLVFPVLI----RGGKPTL--------LFTFVLAFLFCTLNGYLQSRYL 131
Query: 448 SHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK-GYMI 594
S + Y F G ++ V M INI SD +L L G+ GY I
Sbjct: 132 SQFAVYAEDWVTHPCFLTGFALWLVGMVINIHSDHILRNLRKPGETGYKI 181
[74][TOP]
>UniRef100_UPI0000501F93 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.99.5) (Steroid 5-
alpha-reductase 1) (SR type 1). n=1 Tax=Rattus
norvegicus RepID=UPI0000501F93
Length = 214
Score = 74.3 bits (181), Expect = 7e-12
Identities = 55/173 (31%), Positives = 85/173 (49%), Gaps = 5/173 (2%)
Frame = +1
Query: 91 TFISLTFLQAPYGKHHRPGWGPNLSPPL--AWFLMESPALWFTLYLF--PHGKNSSNPKS 258
+ + L + +PYG++ P W P + P AWF+ E P++ + LY + P N +
Sbjct: 23 SIVGLRSVGSPYGRYS-PQW-PGIRVPARPAWFIQELPSMAWPLYEYIRPAAARLGNLPN 80
Query: 259 IILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQA 438
+L+ FLIHY RT+++P + R K +L T +AFLF N YVQ+
Sbjct: 81 RVLLAMFLIHYVQRTLVFPVLI----RGGKPTLLVT--------FVLAFLFCTFNGYVQS 128
Query: 439 KWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK-GYMI 594
+++S + Y F G ++ V M INI SD +L L G+ GY I
Sbjct: 129 RYLSQFAVYAEDWVTHPCFLTGFALWLVGMVINIHSDHILRNLRKPGETGYKI 181
[75][TOP]
>UniRef100_UPI0000501F92 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.99.5) (Steroid 5-
alpha-reductase 1) (SR type 1). n=1 Tax=Rattus
norvegicus RepID=UPI0000501F92
Length = 258
Score = 74.3 bits (181), Expect = 7e-12
Identities = 55/173 (31%), Positives = 85/173 (49%), Gaps = 5/173 (2%)
Frame = +1
Query: 91 TFISLTFLQAPYGKHHRPGWGPNLSPPL--AWFLMESPALWFTLYLF--PHGKNSSNPKS 258
+ + L + +PYG++ P W P + P AWF+ E P++ + LY + P N +
Sbjct: 26 SIVGLRSVGSPYGRYS-PQW-PGIRVPARPAWFIQELPSMAWPLYEYIRPAAARLGNLPN 83
Query: 259 IILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQA 438
+L+ FLIHY RT+++P + R K +L T +AFLF N YVQ+
Sbjct: 84 RVLLAMFLIHYVQRTLVFPVLI----RGGKPTLLVT--------FVLAFLFCTFNGYVQS 131
Query: 439 KWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK-GYMI 594
+++S + Y F G ++ V M INI SD +L L G+ GY I
Sbjct: 132 RYLSQFAVYAEDWVTHPCFLTGFALWLVGMVINIHSDHILRNLRKPGETGYKI 184
[76][TOP]
>UniRef100_P24008-2 Isoform Short of 3-oxo-5-alpha-steroid 4-dehydrogenase 1 n=1
Tax=Rattus norvegicus RepID=P24008-2
Length = 255
Score = 74.3 bits (181), Expect = 7e-12
Identities = 55/173 (31%), Positives = 85/173 (49%), Gaps = 5/173 (2%)
Frame = +1
Query: 91 TFISLTFLQAPYGKHHRPGWGPNLSPPL--AWFLMESPALWFTLYLF--PHGKNSSNPKS 258
+ + L + +PYG++ P W P + P AWF+ E P++ + LY + P N +
Sbjct: 23 SIVGLRSVGSPYGRYS-PQW-PGIRVPARPAWFIQELPSMAWPLYEYIRPAAARLGNLPN 80
Query: 259 IILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQA 438
+L+ FLIHY RT+++P + R K +L T +AFLF N YVQ+
Sbjct: 81 RVLLAMFLIHYVQRTLVFPVLI----RGGKPTLLVT--------FVLAFLFCTFNGYVQS 128
Query: 439 KWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK-GYMI 594
+++S + Y F G ++ V M INI SD +L L G+ GY I
Sbjct: 129 RYLSQFAVYAEDWVTHPCFLTGFALWLVGMVINIHSDHILRNLRKPGETGYKI 181
[77][TOP]
>UniRef100_P24008 3-oxo-5-alpha-steroid 4-dehydrogenase 1 n=1 Tax=Rattus norvegicus
RepID=S5A1_RAT
Length = 259
Score = 74.3 bits (181), Expect = 7e-12
Identities = 55/173 (31%), Positives = 85/173 (49%), Gaps = 5/173 (2%)
Frame = +1
Query: 91 TFISLTFLQAPYGKHHRPGWGPNLSPPL--AWFLMESPALWFTLYLF--PHGKNSSNPKS 258
+ + L + +PYG++ P W P + P AWF+ E P++ + LY + P N +
Sbjct: 27 SIVGLRSVGSPYGRYS-PQW-PGIRVPARPAWFIQELPSMAWPLYEYIRPAAARLGNLPN 84
Query: 259 IILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQA 438
+L+ FLIHY RT+++P + R K +L T +AFLF N YVQ+
Sbjct: 85 RVLLAMFLIHYVQRTLVFPVLI----RGGKPTLLVT--------FVLAFLFCTFNGYVQS 132
Query: 439 KWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK-GYMI 594
+++S + Y F G ++ V M INI SD +L L G+ GY I
Sbjct: 133 RYLSQFAVYAEDWVTHPCFLTGFALWLVGMVINIHSDHILRNLRKPGETGYKI 185
[78][TOP]
>UniRef100_B9EL81 3-oxo-5-alpha-steroid 4-dehydrogenase 2 n=1 Tax=Salmo salar
RepID=B9EL81_SALSA
Length = 253
Score = 73.9 bits (180), Expect = 9e-12
Identities = 55/184 (29%), Positives = 84/184 (45%), Gaps = 2/184 (1%)
Frame = +1
Query: 37 EDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPP--LAWFLMESPALWF 210
++++ +Y + A + T Q PYG++ P + P LAWFL E P+
Sbjct: 4 KENVIHYLSWGFIVGAVAYLLQQTRTQTPYGRYVTLDGTPGRTCPAKLAWFLQELPSFLV 63
Query: 211 TLYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSI 390
+ L + +L+ F +HYF RT IY L T+ + S PL I
Sbjct: 64 PMLLLLSTDTQPSLGKDLLLWTFCLHYFQRTFIYS----LLTKGRPS---------PLYI 110
Query: 391 AFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLX 570
F A +F +N ++Q ++ H YD+ GLL+FF+ M INI SD +LL L
Sbjct: 111 VFSAVVFCSVNGFLQGHYMLHCATYDDAWQTDIRLGTGLLMFFLGMAINIHSDHILLNLR 170
Query: 571 GEGK 582
G+
Sbjct: 171 KPGE 174
[79][TOP]
>UniRef100_Q14C33 Srd5a1 protein n=1 Tax=Mus musculus RepID=Q14C33_MOUSE
Length = 209
Score = 73.9 bits (180), Expect = 9e-12
Identities = 53/170 (31%), Positives = 81/170 (47%), Gaps = 3/170 (1%)
Frame = +1
Query: 94 FISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLY--LFPHGKNSSNPKSIIL 267
F+ L + + YG++ G + AWFL E P++ + LY + P N + +L
Sbjct: 24 FVGLQMVGSSYGRYSSQWSGRRVPARPAWFLQELPSMAWPLYECIRPAAARLGNLPNRVL 83
Query: 268 ITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWV 447
+ FLIHY RT+++P + R K +L L +AFLF LN Y+Q++++
Sbjct: 84 LAMFLIHYVQRTLVFPVLI----RGGKPTL--------LFTFVLAFLFCTLNGYLQSRYL 131
Query: 448 SHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEG-KGYMI 594
S + Y F G ++ V M INI SD +L L G GY I
Sbjct: 132 SQFAVYAEDWITHPCFLTGFALWLVGMVINIHSDHILRNLRKPGDTGYKI 181
[80][TOP]
>UniRef100_A7V280 Putative uncharacterized protein n=1 Tax=Bacteroides uniformis ATCC
8492 RepID=A7V280_BACUN
Length = 256
Score = 73.9 bits (180), Expect = 9e-12
Identities = 54/188 (28%), Positives = 81/188 (43%), Gaps = 7/188 (3%)
Frame = +1
Query: 49 FNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFP 228
F L + +A FI+L F++A YG WG +++ LAW LME+P L+
Sbjct: 6 FQIFLWVMSAVALVVFIALYFVKAGYGMFRTASWGISINNKLAWVLMEAPVFIVMFGLWG 65
Query: 229 HGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFL 408
F +HY R I+PF L K S P++I M +
Sbjct: 66 KSGAGFAVPVYFFFLLFQLHYLQRAFIFPF------------LLKGKSRMPVAIMAMGIV 113
Query: 409 FNLLNSYVQAKWVSHYKNYDNGLCFWGVFFG-----GLLVFFVXMGINIWSDKVL--LRL 567
FNLLN +QA + ++ W G+++FF M +N+ SD V+ LR
Sbjct: 114 FNLLNGMMQAGGLFYFAPEGLYADGWAYLLKPHALLGIILFFAGMFVNLHSDYVIRHLRR 173
Query: 568 XGEGKGYM 591
G+ K Y+
Sbjct: 174 PGDTKHYL 181
[81][TOP]
>UniRef100_UPI0001869A4F hypothetical protein BRAFLDRAFT_116313 n=1 Tax=Branchiostoma
floridae RepID=UPI0001869A4F
Length = 263
Score = 73.6 bits (179), Expect = 1e-11
Identities = 57/188 (30%), Positives = 88/188 (46%), Gaps = 5/188 (2%)
Frame = +1
Query: 46 LFNYALLTLFLIAPPTFISLTFLQ-APYGKHHRPGWGPNLSPP-LAWFLMESPALWFT-- 213
L +Y + ++ PT LTF+ A YG++ P P +AW + E PA
Sbjct: 14 LLDYLAYGMIAVSIPTCFLLTFVTTALYGRNSTQFIVPGFLPARVAWVIQELPAFVVPCL 73
Query: 214 LYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIA 393
L L + +L+ +++HYF+R++I+P L + PL
Sbjct: 74 LLLTTQADRIGYLPNRLLLALYMVHYFHRSLIFPM------------LIRGGKPTPLVPF 121
Query: 394 FMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXG 573
+A LF + N Y+QA+++S Y Y +G F G+L+F V M INI SD +L L
Sbjct: 122 LLALLFCVYNGYMQARYLSQYARYPDGWLTDPRFIVGILMFAVGMAINIHSDHILRNLRK 181
Query: 574 EGK-GYMI 594
G+ GY I
Sbjct: 182 PGETGYKI 189
[82][TOP]
>UniRef100_B5D4A5 Putative uncharacterized protein n=1 Tax=Bacteroides plebeius DSM
17135 RepID=B5D4A5_9BACE
Length = 306
Score = 73.6 bits (179), Expect = 1e-11
Identities = 54/191 (28%), Positives = 95/191 (49%), Gaps = 10/191 (5%)
Frame = +1
Query: 49 FNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPA-LWFTLYLF 225
+ L L +A F++L F++A YG WG ++ + W LMESP+ + L+ +
Sbjct: 57 YQIMLYVLSFLAVIVFVALYFVKAGYGMFRTRSWGWSVPNKVGWVLMESPSFVVMGLWAW 116
Query: 226 PHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAF 405
G + P++ + + F++HYF R+ ++P L K S PL+I M
Sbjct: 117 KAGVEAYTPQA-VFVGLFMLHYFQRSFVFPL------------LMKGKSRMPLAIMAMGI 163
Query: 406 LFNLLNSYVQAKWVSHYK-----NYDNGLCFW--GVFFGGLLVFFVXMGINIWSDKVL-- 558
LFN++N+ + A S + Y++ FW + + G +FF+ M IN+ +D V+
Sbjct: 164 LFNVINATLLA--ASFFSCALPGKYESA-TFWTNPLPWVGAAIFFIGMAINLHADHVIRN 220
Query: 559 LRLXGEGKGYM 591
LR G+ + Y+
Sbjct: 221 LRKPGDTRHYL 231
[83][TOP]
>UniRef100_C3YKJ9 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
RepID=C3YKJ9_BRAFL
Length = 263
Score = 73.6 bits (179), Expect = 1e-11
Identities = 57/188 (30%), Positives = 88/188 (46%), Gaps = 5/188 (2%)
Frame = +1
Query: 46 LFNYALLTLFLIAPPTFISLTFLQ-APYGKHHRPGWGPNLSPP-LAWFLMESPALWFT-- 213
L +Y + ++ PT LTF+ A YG++ P P +AW + E PA
Sbjct: 14 LLDYLAYGMIAVSIPTCFLLTFVTTALYGRNSTQFIVPGFLPARVAWVIQELPAFVVPCL 73
Query: 214 LYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIA 393
L L + +L+ +++HYF+R++I+P L + PL
Sbjct: 74 LLLTTQADRIGYLPNRLLLALYMVHYFHRSLIFPM------------LIRGGKPTPLVPF 121
Query: 394 FMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXG 573
+A LF + N Y+QA+++S Y Y +G F G+L+F V M INI SD +L L
Sbjct: 122 LLALLFCVYNGYMQARYLSQYARYPDGWLTDPRFIVGILMFAVGMAINIHSDHILRNLRK 181
Query: 574 EGK-GYMI 594
G+ GY I
Sbjct: 182 PGETGYKI 189
[84][TOP]
>UniRef100_A9UPT2 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9UPT2_MONBE
Length = 257
Score = 73.2 bits (178), Expect = 1e-11
Identities = 55/193 (28%), Positives = 94/193 (48%), Gaps = 7/193 (3%)
Frame = +1
Query: 37 EDSLFNYALLTLFLIAPPTFISL-TFLQAPYGKH---HRPGWGPNLSPPLAWFLMESPAL 204
E L + L + + PT I+L + +A YG++ ++ +G N++ LAW + ESP L
Sbjct: 3 ERDLVEWLALAVAVTGVPTVIALLSGARAAYGRYVDDNKGLYGFNMNGKLAWIIQESPCL 62
Query: 205 W--FTLYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGF 378
+ F H +N + +L F+ HY +RT+++P LFL +
Sbjct: 63 FMGFLNLWNCHANVITNKPNALLFAFFIFHYVHRTLVFP--LFLKGKDT----------- 109
Query: 379 PLSIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVL 558
P+ I MAF F +N Y+Q W++ + YD+ F G+++ + + +N+ SD L
Sbjct: 110 PVLIMLMAFFFCTINGYIQTAWLTRVQAYDDAYATSPRFIIGMVLAGLGLFVNLHSDYTL 169
Query: 559 LRLXGEG-KGYMI 594
+ L G K Y I
Sbjct: 170 IYLRKPGEKDYKI 182
[85][TOP]
>UniRef100_A8WMD6 Putative uncharacterized protein n=1 Tax=Caenorhabditis briggsae
RepID=A8WMD6_CAEBR
Length = 248
Score = 73.2 bits (178), Expect = 1e-11
Identities = 58/189 (30%), Positives = 89/189 (47%), Gaps = 2/189 (1%)
Frame = +1
Query: 34 KEDSLFNYALLTLFLIAPPTFISLTF-LQAPYGKHHRPGWGPNLSPPLAWFLMESPALWF 210
+E+++ A L + A F +L F L A YG++ +SP LAWF+ E+P+ +
Sbjct: 5 EEETILTMAWL-MIASAIVVFAALRFGLTAGYGRYTNTA-RLGISPRLAWFIQEAPSFFI 62
Query: 211 TLYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSI 390
Y +G ++S L FL+HYFNR I+P ++ TT PL I
Sbjct: 63 PFYYLFNGTSNSGH---YLTRVFLLHYFNRVFIFPLKIRSTTVS------------PLYI 107
Query: 391 AFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLX 570
A F N ++Q W + Y+ + L + G L+FF M IN +D++L L
Sbjct: 108 MLSAIFFCCYNGFMQGYWNAFYQPEEGALT--ARHYIGSLLFFYGMYINHKADRILFNLR 165
Query: 571 GEGK-GYMI 594
G+ GY I
Sbjct: 166 APGETGYKI 174
[86][TOP]
>UniRef100_B3S6K7 Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens
RepID=B3S6K7_TRIAD
Length = 239
Score = 72.0 bits (175), Expect = 3e-11
Identities = 48/148 (32%), Positives = 75/148 (50%), Gaps = 2/148 (1%)
Frame = +1
Query: 31 QKEDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWF 210
Q+ D L N A+ +F + T SL FL APYG++ R G+G ++ L WF+ E P+L
Sbjct: 22 QELDLLRNLAI-GMFGLGACTLPSLMFLTAPYGRYTRDGFGYTINGKLMWFIQEMPSLLI 80
Query: 211 TLYLF--PHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPL 384
+ + N + IL+ FL+HY RT+I+PF L R K + P
Sbjct: 81 PIIMLFEDDADQIHNLPNRILLGQFLLHYTQRTLIFPFLL----RGGKPT--------PA 128
Query: 385 SIAFMAFLFNLLNSYVQAKWVSHYKNYD 468
+ MA F + N Y+Q ++++ + YD
Sbjct: 129 MVGLMATCFCIYNGYLQGRYLTAFAVYD 156
[87][TOP]
>UniRef100_Q14C32 Srd5a1 protein n=1 Tax=Mus musculus RepID=Q14C32_MOUSE
Length = 209
Score = 71.6 bits (174), Expect = 4e-11
Identities = 52/170 (30%), Positives = 80/170 (47%), Gaps = 3/170 (1%)
Frame = +1
Query: 94 FISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLY--LFPHGKNSSNPKSIIL 267
F+ L + + YG++ G + AWFL E P++ + LY + P N + +L
Sbjct: 24 FVGLQMVGSSYGRYSSQWSGRRVPARPAWFLQELPSMAWPLYECIRPAAARLGNLPNRVL 83
Query: 268 ITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWV 447
+ FLIHY RT+++P + R K +L L +AFLF LN Y+Q++++
Sbjct: 84 LAMFLIHYVQRTLVFPVLI----RGGKPTL--------LFTFVLAFLFCTLNGYLQSRYL 131
Query: 448 SHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEG-KGYMI 594
S + Y G ++ V M INI SD +L L G GY I
Sbjct: 132 SQFAVYAEDWITHPCLLTGFALWLVGMVINIHSDHILRNLRKPGDTGYKI 181
[88][TOP]
>UniRef100_UPI0000ECCE6E 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.99.5) (Steroid 5-
alpha-reductase 1) (SR type 1) (S5AR). n=1 Tax=Gallus
gallus RepID=UPI0000ECCE6E
Length = 257
Score = 70.1 bits (170), Expect = 1e-10
Identities = 57/192 (29%), Positives = 89/192 (46%), Gaps = 1/192 (0%)
Frame = +1
Query: 22 PFFQKEDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPA 201
P Q+ L +Y L+ L ++ + L F+ PYG++ +G L AW L E PA
Sbjct: 8 PREQRLLELLSYGLVALGAVSA---LLLRFIPMPYGRYSSRRFGWLLPARPAWLLQELPA 64
Query: 202 LWFTLYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFP 381
L L L P +++L F++HY +R +I+PF + R+ K + P
Sbjct: 65 LLVPLALAACIPVWRLPNAVLLGC-FILHYVHRALIFPFLI----RQGKPT--------P 111
Query: 382 LSIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLL 561
+A LF + N Y+Q + +S Y Y + F G + + + M INI SD +L
Sbjct: 112 FFTFLLALLFCIYNGYLQGRSLSTYAEYPSDWLKHPCFIAGFMGWLIGMAINIHSDHILR 171
Query: 562 RLXGEGK-GYMI 594
L G+ GY I
Sbjct: 172 NLRKPGETGYKI 183
[89][TOP]
>UniRef100_UPI00016E9469 UPI00016E9469 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E9469
Length = 265
Score = 69.3 bits (168), Expect = 2e-10
Identities = 48/169 (28%), Positives = 78/169 (46%), Gaps = 3/169 (1%)
Frame = +1
Query: 97 ISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALW--FTLYLFPHGKNSSNPKSIILI 270
I L PYG++ +G ++ +AWF+ E PA F+L ++ +S + +LI
Sbjct: 33 IRLRRQNVPYGRYSTSKYGFPVNAKVAWFIQELPAFLVPFSLLVWTSSARTSLLPNQLLI 92
Query: 271 TPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVS 450
+ HY R +IYPF L + P +AF+F + N Y+Q +++S
Sbjct: 93 AMYFCHYVQRALIYPF------------LIRGGKPTPFVSFALAFVFCVYNGYMQIRYLS 140
Query: 451 HYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK-GYMI 594
HY Y F G +++F +N+ SD +L L G+ GY I
Sbjct: 141 HYAVYPAHWFTHPCFITGSVLWFTGWLVNVHSDHILRNLRQPGESGYKI 189
[90][TOP]
>UniRef100_Q566V2 Zgc:112455 n=1 Tax=Danio rerio RepID=Q566V2_DANRE
Length = 217
Score = 69.3 bits (168), Expect = 2e-10
Identities = 48/164 (29%), Positives = 71/164 (43%), Gaps = 1/164 (0%)
Frame = +1
Query: 94 FISLTFLQAPYGKHHRPGWGPNLSPP-LAWFLMESPALWFTLYLFPHGKNSSNPKSIILI 270
FI L A YG++ + P LAWFL E PAL L L + +++
Sbjct: 9 FICLMKSHAAYGRYVDTSGSSMMVPARLAWFLQEIPALLVPLLLMVTTDGNHGTGKHLML 68
Query: 271 TPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVS 450
F +HYF R+ IY SL +P +I + +N ++QA ++
Sbjct: 69 WTFCLHYFQRSCIY-------------SLLTKGRPYPFNIMLTGVVVCSINGFLQAHYLL 115
Query: 451 HYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK 582
H + N GL++FF+ MGINI SD +L L G+
Sbjct: 116 HCATFHNTWFSDACLLTGLIIFFLGMGINIHSDHILRNLRNPGE 159
[91][TOP]
>UniRef100_B6KVL0 3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2, putative n=1
Tax=Toxoplasma gondii ME49 RepID=B6KVL0_TOXGO
Length = 324
Score = 69.3 bits (168), Expect = 2e-10
Identities = 49/177 (27%), Positives = 85/177 (48%), Gaps = 18/177 (10%)
Frame = +1
Query: 91 TFISLTFLQAPYGKHHRPG----WGPNLSPPLAWFLMESPALWFTLYLFPHGK-NSSNPK 255
T + F++AP+GK WGP++ +AW + E P+ + + + + P
Sbjct: 60 TVVGQIFIRAPWGKFRNDAKSRVWGPSVPCAVAWMIQECPSFFIPFSVLVGTEWLAGRPI 119
Query: 256 SIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQ 435
+ IL+ F HY +R+++YP RL++ TR +++ PL I+ MA LF N +Q
Sbjct: 120 NKILLVLFTTHYAHRSLVYPARLYVHTRYQEN------QSMPLGISAMAVLFCTYNGMIQ 173
Query: 436 AKWVSHYKNYDNGL------------CFWGV-FFGGLLVFFVXMGINIWSDKVLLRL 567
+ W + +Y + L C + G+ VF M +NI SD +L++L
Sbjct: 174 S-WSAISFDYSSELDPFLAPRASVDDCSAALRLISGVCVFLWGMSVNIRSDYILMKL 229
[92][TOP]
>UniRef100_UPI000194C171 PREDICTED: similar to 3-oxo-5 alpha-steroid 4-dehydrogenase 2 n=1
Tax=Taeniopygia guttata RepID=UPI000194C171
Length = 255
Score = 68.6 bits (166), Expect = 4e-10
Identities = 54/157 (34%), Positives = 69/157 (43%), Gaps = 4/157 (2%)
Frame = +1
Query: 124 YGKHHRPGWGPN--LSPPLAWFLMESPALWF-TLYLFPHGKNSSNPKSI-ILITPFLIHY 291
YGKH P L AWFL E P+ L L P +L F HY
Sbjct: 33 YGKHEERPCPPRGRLPARCAWFLQELPSFLVPALLLALRSPPRLEPLGCRLLCCLFCWHY 92
Query: 292 FNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYDN 471
F RT IYPF TR + FPL + F LF + N ++Q ++ + Y N
Sbjct: 93 FYRTFIYPF----FTRGRP---------FPLQLLFFGMLFCIYNGFLQGYYLIYCAEYPN 139
Query: 472 GLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK 582
C F GLL+F + MGINI SD +L +L G+
Sbjct: 140 NWCTDIRFTSGLLLFLLGMGINIHSDLLLRQLRKPGE 176
[93][TOP]
>UniRef100_Q28891 3-oxo-5-alpha-steroid 4-dehydrogenase 1 n=1 Tax=Macaca fascicularis
RepID=S5A1_MACFA
Length = 263
Score = 68.2 bits (165), Expect = 5e-10
Identities = 50/163 (30%), Positives = 75/163 (46%), Gaps = 6/163 (3%)
Frame = +1
Query: 124 YGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFPHGKNSSNPK-----SIILITPFLIH 288
YG+H P + + AW + E P+L LY + + S P+ + IL+ FL+H
Sbjct: 42 YGRHASPSFRVRVPARAAWVVQELPSLALPLYQYA---SESAPRLRSAPNCILLAMFLVH 98
Query: 289 YFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYD 468
Y +R +IYPF L + PL MA +F N Y+Q++++SH+ Y
Sbjct: 99 YGHRCLIYPF------------LMRGGKPMPLLACTMAIMFCTFNGYLQSRYLSHWAVYA 146
Query: 469 NGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEG-KGYMI 594
+ F G ++ M INI SD +L L G GY I
Sbjct: 147 DDWVTDPRFLIGFGLWLAGMLINIHSDHILRNLRKPGDTGYKI 189
[94][TOP]
>UniRef100_UPI000056CE95 hypothetical protein LOC550388 n=1 Tax=Danio rerio
RepID=UPI000056CE95
Length = 217
Score = 67.4 bits (163), Expect = 8e-10
Identities = 47/164 (28%), Positives = 71/164 (43%), Gaps = 1/164 (0%)
Frame = +1
Query: 94 FISLTFLQAPYGKHHRPGWGPNLSPP-LAWFLMESPALWFTLYLFPHGKNSSNPKSIILI 270
FI L A YG++ + P LAWFL E PAL L L + +++
Sbjct: 9 FICLMKSHAAYGRYVDTSGSSMMVPARLAWFLQEIPALLVPLLLMMTTDGNHGTGKHLML 68
Query: 271 TPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVS 450
F +HYF R+ IY SL +P +I + +N ++QA ++
Sbjct: 69 WTFCLHYFQRSCIY-------------SLLTKGRPYPFNIMLTGVVVCSINGFLQAHYLL 115
Query: 451 HYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK 582
H + + GL++FF+ MGINI SD +L L G+
Sbjct: 116 HCATFHSTWFSDACLLTGLIIFFLGMGINIHSDHILRNLRNPGE 159
[95][TOP]
>UniRef100_Q24HG9 3-oxo-5-alpha-steroid 4-dehydrogenase family protein n=1
Tax=Tetrahymena thermophila SB210 RepID=Q24HG9_TETTH
Length = 266
Score = 67.0 bits (162), Expect = 1e-09
Identities = 54/177 (30%), Positives = 79/177 (44%), Gaps = 15/177 (8%)
Frame = +1
Query: 109 FLQAPYGKHHRPGWGPNLSPPLAWFLMESPAL----WFTLYLFPHGKNSSNPKSIILITP 276
++ YGK + + NL ++WF E P L WF + + N + +++ P
Sbjct: 34 YIPINYGKQLKSFFNFNLGK-MSWFFFEVPNLIIAGWFMT------QYTDNLVNYVMLLP 86
Query: 277 FLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWV-SH 453
F+IHY NR+IIYP +L P+ + A F NSY+QAK + S
Sbjct: 87 FIIHYINRSIIYPM-----------TLQNNTKPIPIEVCLFATSFTTCNSYLQAKSILSV 135
Query: 454 YKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRL----------XGEGKGYMI 594
++ + L W V G L+F M INI SD+ L L GE K Y+I
Sbjct: 136 QESKFSDLFKWNVLL-GYLIFIFGMYINIKSDRYLQSLKKNLSTANSKTGEKKNYVI 191
[96][TOP]
>UniRef100_UPI0000E800BE PREDICTED: similar to 3-oxo-5 alpha-steroid 4-dehydrogenase 2 n=1
Tax=Gallus gallus RepID=UPI0000E800BE
Length = 255
Score = 65.9 bits (159), Expect = 2e-09
Identities = 55/164 (33%), Positives = 73/164 (44%), Gaps = 6/164 (3%)
Frame = +1
Query: 109 FLQAP--YGKHHRPGWGPN--LSPPLAWFLMESPALWF-TLYLFPHGKNSSNPKSI-ILI 270
+L+ P YGKH P L AWF+ E P+ L L P +L
Sbjct: 26 YLRVPSRYGKHEERLCRPRGRLPARCAWFVQELPSFLVPALLLALRSPPRLEPLGCRLLC 85
Query: 271 TPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVS 450
F HYF RT IYPF TR + FPL + F LF + N ++Q ++
Sbjct: 86 CLFCWHYFYRTFIYPF----FTRGRP---------FPLQLLFFGTLFCVYNGFLQGYYLI 132
Query: 451 HYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK 582
+ Y N C F GLL+F + MGINI SD +L +L G+
Sbjct: 133 YCAEYPNDWCTDIRFTSGLLLFLLGMGINIHSDLLLRQLRKPGE 176
[97][TOP]
>UniRef100_UPI0000ECC85C 3-oxo-5-alpha-steroid 4-dehydrogenase 2 (EC 1.3.99.5) (Steroid 5-
alpha-reductase 2) (SR type 2) (5 alpha-SR2) (Type II
5-alpha reductase). n=1 Tax=Gallus gallus
RepID=UPI0000ECC85C
Length = 257
Score = 65.9 bits (159), Expect = 2e-09
Identities = 55/164 (33%), Positives = 73/164 (44%), Gaps = 6/164 (3%)
Frame = +1
Query: 109 FLQAP--YGKHHRPGWGPN--LSPPLAWFLMESPALWF-TLYLFPHGKNSSNPKSI-ILI 270
+L+ P YGKH P L AWF+ E P+ L L P +L
Sbjct: 28 YLRVPSRYGKHEERLCRPRGRLPARCAWFVQELPSFLVPALLLALRSPPRLEPLGCRLLC 87
Query: 271 TPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVS 450
F HYF RT IYPF TR + FPL + F LF + N ++Q ++
Sbjct: 88 CLFCWHYFYRTFIYPF----FTRGRP---------FPLQLLFFGTLFCVYNGFLQGYYLI 134
Query: 451 HYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK 582
+ Y N C F GLL+F + MGINI SD +L +L G+
Sbjct: 135 YCAEYPNDWCTDIRFTSGLLLFLLGMGINIHSDLLLRQLRKPGE 178
[98][TOP]
>UniRef100_B0MXH1 Putative uncharacterized protein n=1 Tax=Alistipes putredinis DSM
17216 RepID=B0MXH1_9BACT
Length = 253
Score = 65.9 bits (159), Expect = 2e-09
Identities = 50/185 (27%), Positives = 79/185 (42%), Gaps = 4/185 (2%)
Frame = +1
Query: 49 FNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFP 228
FN L+ + L+A +I+L + +A YG +G + + W LME P L+
Sbjct: 5 FNIFLIVMALLALAVYIALHYFEAGYGYLFNRKYGFPIPNRIGWVLMECPVFIAMTVLWL 64
Query: 229 HGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFL 408
+ + L+ F HY R I+P L + S P I M L
Sbjct: 65 LSDRTWEAAPLALLILFQGHYLQRAFIFPL------------LIRGNSKMPAGIVGMGML 112
Query: 409 FNLLNSYVQAKWVSHYK--NYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVL--LRLXGE 576
FN LN+ +Q W+ + +Y G F+ G +F M IN+ SD ++ LR G+
Sbjct: 113 FNTLNALMQGGWIFYISPADYYEGWFSKPYFYIGAALFVAGMVINLHSDYIIRHLRKPGD 172
Query: 577 GKGYM 591
+ Y+
Sbjct: 173 TRHYI 177
[99][TOP]
>UniRef100_Q19605 Protein F19H6.4, partially confirmed by transcript evidence n=1
Tax=Caenorhabditis elegans RepID=Q19605_CAEEL
Length = 243
Score = 65.9 bits (159), Expect = 2e-09
Identities = 56/171 (32%), Positives = 81/171 (47%), Gaps = 4/171 (2%)
Frame = +1
Query: 94 FISLTF-LQAPYGKH-HRPGWGPNLSPPLAWFLMESPALWFTLYLFPHGKNSSNPKSIIL 267
F++LT A YG++ R +G N P LAWF+ E+PA + LY G ++S + L
Sbjct: 20 FLALTRGFTAGYGRYADRSKYGIN--PKLAWFIQEAPAFFIPLYYLRRGPSNSGYE---L 74
Query: 268 ITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWV 447
FL HYF R +IYP R+ TT+ P++I A F N ++Q W
Sbjct: 75 NAAFLFHYFFRALIYPCRIRSTTKS------------PVAIVAAATFFCAYNGFLQGYWN 122
Query: 448 SHYKNYDNGLCFWGV-FFGGLLVFFVXMGINIWSDKVLLRLXGE-GKGYMI 594
+ Y+ + W G L++ M IN SD +L L + G GY I
Sbjct: 123 AFYQPEEP----WTTRKLVGSLMYCTGMYINHKSDTILRELRADGGTGYKI 169
[100][TOP]
>UniRef100_UPI00005A5669 PREDICTED: similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1
(Steroid 5-alpha-reductase 1) (SR type 1) (S5AR) n=1
Tax=Canis lupus familiaris RepID=UPI00005A5669
Length = 255
Score = 65.5 bits (158), Expect = 3e-09
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 3/160 (1%)
Frame = +1
Query: 124 YGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFPH--GKNSSNPKSIILITPFLIHYFN 297
YG++ PG + AW L E P+L L++ + + IL+ FL+HY
Sbjct: 34 YGRYASPGAAFGVPARAAWALQELPSLAVPLWVCARTAAERLRRAPNRILLAMFLLHYAQ 93
Query: 298 RTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYDNGL 477
R++I+PF L + PL +AF F + N Y+Q++++S Y Y +
Sbjct: 94 RSLIFPF------------LIRGGKPMPLYTCVLAFTFCVYNGYLQSRYLSQYAVYADDW 141
Query: 478 CFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK-GYMI 594
F G ++ + M INI SD +L L G+ GY I
Sbjct: 142 VTDPRFLVGFCLWLIGMLINIHSDHILRNLRKPGETGYKI 181
[101][TOP]
>UniRef100_UPI0000EB09A9 Prostatic steroid 5-alpha-reductase type I n=1 Tax=Canis lupus
familiaris RepID=UPI0000EB09A9
Length = 253
Score = 65.5 bits (158), Expect = 3e-09
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 3/160 (1%)
Frame = +1
Query: 124 YGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFPH--GKNSSNPKSIILITPFLIHYFN 297
YG++ PG + AW L E P+L L++ + + IL+ FL+HY
Sbjct: 32 YGRYASPGAAFGVPARAAWALQELPSLAVPLWVCARTAAERLRRAPNRILLAMFLLHYAQ 91
Query: 298 RTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYDNGL 477
R++I+PF L + PL +AF F + N Y+Q++++S Y Y +
Sbjct: 92 RSLIFPF------------LIRGGKPMPLYTCVLAFTFCVYNGYLQSRYLSQYAVYADDW 139
Query: 478 CFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK-GYMI 594
F G ++ + M INI SD +L L G+ GY I
Sbjct: 140 VTDPRFLVGFCLWLIGMLINIHSDHILRNLRKPGETGYKI 179
[102][TOP]
>UniRef100_C7T2J8 Steroid 5 alpha-reductase 2 n=1 Tax=Mesocricetus auratus
RepID=C7T2J8_MESAU
Length = 254
Score = 65.5 bits (158), Expect = 3e-09
Identities = 58/197 (29%), Positives = 87/197 (44%), Gaps = 7/197 (3%)
Frame = +1
Query: 13 HQNPFFQKEDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRP-GWGPNLSPPLAWFLM 189
HQ P +L LTL+L P + YGKH + GP L +AWFL
Sbjct: 6 HQGPVLAGSATLATIGALTLYLGKPTS----------YGKHSQSVSSGPLLPARVAWFLQ 55
Query: 190 ESPALWFTLYLFPHGKNSSNPKSI------ILITPFLIHYFNRTIIYPFRLFLTTRRKKS 351
E P+ ++ P G + +S+ +L+ F HYF+RT IY L TR +
Sbjct: 56 ELPS-----FVVPVGMLAWQSRSLFGQPGNVLLGLFSAHYFHRTFIYS----LLTRGRP- 105
Query: 352 SLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMG 531
FP+ + A F + N ++QA ++ + Y F G+ +F + MG
Sbjct: 106 --------FPVMLFLRAIAFCIGNGFLQAYYLIYCAEYPKEWYTDVRFSVGVFLFILGMG 157
Query: 532 INIWSDKVLLRLXGEGK 582
INI SD +L +L G+
Sbjct: 158 INIHSDYLLRQLRKPGE 174
[103][TOP]
>UniRef100_A5PJS2 3-oxo-5-alpha-steroid 4-dehydrogenase 1 n=2 Tax=Bos taurus
RepID=S5A1_BOVIN
Length = 257
Score = 65.1 bits (157), Expect = 4e-09
Identities = 48/172 (27%), Positives = 78/172 (45%), Gaps = 5/172 (2%)
Frame = +1
Query: 94 FISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFPHG----KNSSNPKSI 261
++ L + +PYG++ G L AW + E P+L L + + +
Sbjct: 24 YVLLKLVGSPYGRYASSGSAFGLPARAAWTVQELPSLALPLLACAGAGAPAERLNRWPNC 83
Query: 262 ILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAK 441
IL+ FL+HY R++++PF L + PL +AF+F N Y+Q++
Sbjct: 84 ILLAMFLVHYAQRSLVFPF------------LIRGGKPMPLYAFLLAFIFCTYNGYLQSR 131
Query: 442 WVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK-GYMI 594
++S Y Y + F G ++ + M INI SD VL L G+ GY I
Sbjct: 132 YLSQYAVYADDWLSDPRFLTGSALWLIGMLINIHSDHVLRNLRKPGETGYKI 183
[104][TOP]
>UniRef100_B9Q3D4 3-oxo-5-alpha-steroid 4-dehydrogenase, putative n=2 Tax=Toxoplasma
gondii RepID=B9Q3D4_TOXGO
Length = 389
Score = 65.1 bits (157), Expect = 4e-09
Identities = 51/195 (26%), Positives = 86/195 (44%), Gaps = 36/195 (18%)
Frame = +1
Query: 91 TFISLTFLQAPYGKHHRPG----WGPNLSPPLAWFLMESPALWFTLYLFPHGK-NSSNPK 255
T + F++AP+GK WGP++ +AW + E P+ + + + + P
Sbjct: 60 TVVGQIFIRAPWGKFRNDAKSRVWGPSVPCAVAWMIQECPSFFIPFSVLVGTEWLAGRPI 119
Query: 256 SIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQ 435
+ IL+ F HY +R+++YP RL++ TR +++ PL I+ MA LF N +Q
Sbjct: 120 NKILLVLFTTHYAHRSLVYPARLYVHTRYQEN------QSMPLGISAMAVLFCTYNGMIQ 173
Query: 436 AKWVSHYKNYDNG----LCFWGV---------------------------FFGGLLVFFV 522
+ W + +Y + L F GV G+ VF
Sbjct: 174 S-WSAISFDYSSEVRGVLYFCGVIKKCVGMQLDPFLAPRASVDDCSAALRLISGVCVFLW 232
Query: 523 XMGINIWSDKVLLRL 567
M +NI SD +L++L
Sbjct: 233 GMSVNIRSDYILMKL 247
[105][TOP]
>UniRef100_UPI0000509D99 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5
alpha-steroid delta 4-dehydrogenase alpha 2) n=1
Tax=Xenopus (Silurana) tropicalis RepID=UPI0000509D99
Length = 239
Score = 64.7 bits (156), Expect = 5e-09
Identities = 52/174 (29%), Positives = 74/174 (42%), Gaps = 3/174 (1%)
Frame = +1
Query: 55 YALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPN---LSPPLAWFLMESPALWFTLYLF 225
Y L L +I+ I A YGKH G N + WF+ E P+ + +
Sbjct: 10 YMSLCLAIISVLFLIRQFTYPAAYGKHVATGKKQNGFMVPAKYGWFIQELPSFLVPVVVI 69
Query: 226 PHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAF 405
+ + ++ +L F HYF RT IY TR + S PL I MA
Sbjct: 70 LYRQQCNSLGCKMLSFMFCGHYFQRTFIYS----AFTRGRPS---------PLRIVLMAV 116
Query: 406 LFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRL 567
+F N ++Q + + Y C F G+L+F + MGINI SD +L RL
Sbjct: 117 VFCTYNGFLQGHCLVYVAEYPKDWCMDLRFISGVLIFCLGMGINIHSDHILRRL 170
[106][TOP]
>UniRef100_UPI000069D99C 3-oxo-5-alpha-steroid 4-dehydrogenase 2 (EC 1.3.99.5) (Steroid 5-
alpha-reductase 2) (SR type 2) (5 alpha-SR2) (Type II
5-alpha reductase). n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069D99C
Length = 233
Score = 64.7 bits (156), Expect = 5e-09
Identities = 52/174 (29%), Positives = 74/174 (42%), Gaps = 3/174 (1%)
Frame = +1
Query: 55 YALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPN---LSPPLAWFLMESPALWFTLYLF 225
Y L L +I+ I A YGKH G N + WF+ E P+ + +
Sbjct: 10 YMSLCLAIISVLFLIRQFTYPAAYGKHVATGKKQNGFMVPAKYGWFIQELPSFLVPVVVI 69
Query: 226 PHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAF 405
+ + ++ +L F HYF RT IY TR + S PL I MA
Sbjct: 70 LYRQQCNSLGCKMLSFMFCGHYFQRTFIYS----AFTRGRPS---------PLRIVLMAV 116
Query: 406 LFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRL 567
+F N ++Q + + Y C F G+L+F + MGINI SD +L RL
Sbjct: 117 VFCTYNGFLQGHCLVYVAEYPKDWCMDLRFISGVLIFCLGMGINIHSDHILRRL 170
[107][TOP]
>UniRef100_P18405 3-oxo-5-alpha-steroid 4-dehydrogenase 1 n=1 Tax=Homo sapiens
RepID=S5A1_HUMAN
Length = 259
Score = 64.3 bits (155), Expect = 7e-09
Identities = 50/163 (30%), Positives = 73/163 (44%), Gaps = 6/163 (3%)
Frame = +1
Query: 124 YGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFPHGKNSSNPK-----SIILITPFLIH 288
YG+H P + AW + E P+L LY + + S P+ + IL+ FL+H
Sbjct: 38 YGRHALPSHRLRVPARAAWVVQELPSLALPLYQYA---SESAPRLRSAPNCILLAMFLVH 94
Query: 289 YFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYD 468
Y +R +IYPF L + PL MA +F N Y+Q++++SH Y
Sbjct: 95 YGHRCLIYPF------------LMRGGKPMPLLACTMAIMFCTCNGYLQSRYLSHCAVYA 142
Query: 469 NGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEG-KGYMI 594
+ F G ++ M INI SD +L L G GY I
Sbjct: 143 DDWVTDPRFLIGFGLWLTGMLINIHSDHILRNLRKPGDTGYKI 185
[108][TOP]
>UniRef100_UPI000180C678 PREDICTED: similar to steroid 5 alpha-reductase 1 n=1 Tax=Ciona
intestinalis RepID=UPI000180C678
Length = 258
Score = 63.5 bits (153), Expect = 1e-08
Identities = 45/159 (28%), Positives = 74/159 (46%), Gaps = 2/159 (1%)
Frame = +1
Query: 124 YGKHHRPGWGPNLSPPLAWFLMESPALWF-TLYLFPHGKNSSNPKSIILITPFLIHYFNR 300
YGKH + + LAW + E P+ + L + G + N ++++I+ F HYF R
Sbjct: 37 YGKHTKKSKF-TVDARLAWVIQECPSFFLPVLVTYSVGVENINFSNLLIISAFAFHYFQR 95
Query: 301 TIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLC 480
+ IYP +++ + PL I FM+F F +N Y +K+ + + +
Sbjct: 96 SFIYPM-----------LMNRMSTPLPLRIVFMSFTFTFINGYAISKYEAAHVSLPENWI 144
Query: 481 FWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK-GYMI 594
F G+L++ + INI SD VL L + GY I
Sbjct: 145 NSFQFLTGMLMWASGLLINIHSDHVLRNLRKPNEVGYKI 183
[109][TOP]
>UniRef100_A0BR98 Chromosome undetermined scaffold_122, whole genome shotgun sequence
n=1 Tax=Paramecium tetraurelia RepID=A0BR98_PARTE
Length = 245
Score = 63.5 bits (153), Expect = 1e-08
Identities = 53/181 (29%), Positives = 78/181 (43%), Gaps = 4/181 (2%)
Frame = +1
Query: 46 LFNYALLTLFLIAPPTFISLT--FLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLY 219
+F++ +++ +I + + T L+ YGKH L P + W L E P L + +Y
Sbjct: 1 MFDFQFISVIIILGFSLAAWTADLLKIGYGKHLSHYMKLTLPPRIGWILYECPNLIWFVY 60
Query: 220 LFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFM 399
P N I+L F+ HYFNR IIYP R LS P+ +
Sbjct: 61 FLPAISLDFNRLPILL---FVTHYFNRVIIYPLR-----------LSPLARPIPVEVVAS 106
Query: 400 AFLFNLLNSYVQAKWVSHYKNYDNGLCF--WGVFFGGLLVFFVXMGINIWSDKVLLRLXG 573
A LF N Y+Q ++ + N D L + G+L+F M NI D +L L
Sbjct: 107 AILFTTCNGYIQ---ITTHLNRDLQLYLPDYLRILVGILIFIYGMTSNIKCDNILRGLKK 163
Query: 574 E 576
E
Sbjct: 164 E 164
[110][TOP]
>UniRef100_B2HRW9 Conserved hypothetical membrane protein n=1 Tax=Mycobacterium
marinum M RepID=B2HRW9_MYCMM
Length = 263
Score = 63.2 bits (152), Expect = 2e-08
Identities = 41/178 (23%), Positives = 76/178 (42%), Gaps = 2/178 (1%)
Frame = +1
Query: 40 DSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLY 219
++ ++ L +A I F+Q+PYG+ G NL+P L W+LME PA
Sbjct: 7 NTTYDTVLTIALAVAALVIIGGLFMQSPYGRFGATAGGVNLNPKLGWWLMEIPATVVFAI 66
Query: 220 LFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFM 399
+ G + ++L +L+HY NR +P + ++ S F +S+
Sbjct: 67 FYLTGPQRFDAAPLVLAAIWLLHYGNRGWFFPLSIRQVPGKR--------SSFNISVLAA 118
Query: 400 AFLFNLLNSYVQAKWVSHYKNYDNGLCFW--GVFFGGLLVFFVXMGINIWSDKVLLRL 567
+ ++ Y+ + SH + G + F G LV+ + +WS+ ++ L
Sbjct: 119 GMVITSMHGYLNGAFFSHDYRHQYGTKWLTDPRFLLGTLVYLAGFVLLVWSESIVRNL 176
[111][TOP]
>UniRef100_C3YJH5 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
RepID=C3YJH5_BRAFL
Length = 256
Score = 62.0 bits (149), Expect = 3e-08
Identities = 55/191 (28%), Positives = 84/191 (43%), Gaps = 4/191 (2%)
Frame = +1
Query: 34 KEDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHH-RPGWGPNLSPPLAWFLMESP--AL 204
+E L N A + L L P FI++ A YG++ + W L AW E P A+
Sbjct: 6 EEAFLDNLAYVMLGLSVPVFFITVFVKVAEYGRYTVKSSWA--LPARTAWLFQELPSFAV 63
Query: 205 WFTLYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPL 384
L LF + + +L+ F+ HYF RT I+ S L + P
Sbjct: 64 PVLLVLFGRAGRMTQLPNQVLLAMFVAHYFQRTFIF------------SLLIRGGKQTPF 111
Query: 385 SIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLR 564
I AF+F N Y+Q ++++ + +Y + G+ +F V M IN+ +D VL
Sbjct: 112 HIFRDAFVFCTYNGYLQGRYLAEFAHYPDTWLSEPRCIVGVAMFLVGMAINLHADHVLRN 171
Query: 565 LXGEGK-GYMI 594
L G+ GY I
Sbjct: 172 LRKPGETGYKI 182
[112][TOP]
>UniRef100_C5XPV1 Putative uncharacterized protein Sb03g040050 n=1 Tax=Sorghum
bicolor RepID=C5XPV1_SORBI
Length = 202
Score = 61.6 bits (148), Expect = 4e-08
Identities = 48/140 (34%), Positives = 67/140 (47%), Gaps = 4/140 (2%)
Frame = +1
Query: 187 MESPALWFT--LYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLS 360
MESP LW + L S P + + + HY +RT+++P RL + L
Sbjct: 1 MESPTLWLPPLVLLRSPPPRLSGPLAALPAALYAFHYVHRTLVHPLRL--------ACLR 52
Query: 361 KTPSGFPLSIAFMAFLFNLLNSYVQAKWVSHY--KNYDNGLCFWGVFFGGLLVFFVXMGI 534
+ + PL IA AF F+LLN+YVQA+ + + + C GL +F M
Sbjct: 53 RATAPVPLLIAACAFGFSLLNAYVQARSFALHAGRPASPARC-----LAGLALFAWGMRT 107
Query: 535 NIWSDKVLLRLXGEGKGYMI 594
NI +DK LLRL G GY I
Sbjct: 108 NIAADKELLRLKEAGGGYKI 127
[113][TOP]
>UniRef100_UPI00016DFBD2 UPI00016DFBD2 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFBD2
Length = 259
Score = 61.2 bits (147), Expect = 6e-08
Identities = 50/157 (31%), Positives = 69/157 (43%)
Frame = +1
Query: 112 LQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFPHGKNSSNPKSIILITPFLIHY 291
+ A YG++ P GP LAWFL E PA L L + S+ L FL+HY
Sbjct: 39 IPAQYGRYS-PAEGPTFPAKLAWFLQEVPAFLVPLVLLLQSPETGARASVSLFA-FLLHY 96
Query: 292 FNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYDN 471
F+R+ I+ LT R P+ I A LF LN ++Q + H + ++
Sbjct: 97 FHRSFIF---ASLTQGRP----------VPVEIVLFAALFCCLNGFLQGHHLLHCTSDED 143
Query: 472 GLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK 582
G L+F V M INI SD +L L G+
Sbjct: 144 TWPPRAHKAVGFLLFLVGMTINIHSDHILRNLRKPGE 180
[114][TOP]
>UniRef100_Q566Z4 Novel protein (Zgc:112208) n=1 Tax=Danio rerio RepID=Q566Z4_DANRE
Length = 252
Score = 61.2 bits (147), Expect = 6e-08
Identities = 48/158 (30%), Positives = 68/158 (43%), Gaps = 2/158 (1%)
Frame = +1
Query: 115 QAPYGKHHRPGWGPNLSPPL--AWFLMESPALWFTLYLFPHGKNSSNPKSIILITPFLIH 288
Q YG++ P L P WF+ E P+ + LF ++ IL F +H
Sbjct: 30 QTAYGRYVDTK-SPGLMVPARAGWFIQELPSFLVPVLLFFATESLPGVGKHILFWTFCLH 88
Query: 289 YFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYD 468
YF RT +Y L T+ + S PL I A +F +N ++Q ++ H Y
Sbjct: 89 YFQRTFVYS----LLTKGRPS---------PLHIVVSAVVFCSINGFLQGHYMLHCTQYS 135
Query: 469 NGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK 582
+ F GLLVF M INI SD +L L G+
Sbjct: 136 SDWLTDTRFITGLLVFLCGMAINIHSDYILRNLRKPGE 173
[115][TOP]
>UniRef100_Q504D5 Zgc:112208 n=1 Tax=Danio rerio RepID=Q504D5_DANRE
Length = 252
Score = 61.2 bits (147), Expect = 6e-08
Identities = 48/158 (30%), Positives = 68/158 (43%), Gaps = 2/158 (1%)
Frame = +1
Query: 115 QAPYGKHHRPGWGPNLSPPL--AWFLMESPALWFTLYLFPHGKNSSNPKSIILITPFLIH 288
Q YG++ P L P WF+ E P+ + LF ++ IL F +H
Sbjct: 30 QTAYGRYVDTK-SPGLMVPARAGWFIQELPSFLVPVLLFFATESLPGVGKHILFWTFCLH 88
Query: 289 YFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYD 468
YF RT +Y L T+ + S PL I A +F +N ++Q ++ H Y
Sbjct: 89 YFQRTFVYS----LLTKGRPS---------PLHIVVSAVVFCSINGFLQGHYMLHCTQYS 135
Query: 469 NGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK 582
+ F GLLVF M INI SD +L L G+
Sbjct: 136 SDWLTDTRFITGLLVFLCGMAINIHSDYILRNLRKPGE 173
[116][TOP]
>UniRef100_A2ZZM0 Putative uncharacterized protein n=1 Tax=Oryza sativa Japonica
Group RepID=A2ZZM0_ORYSJ
Length = 256
Score = 61.2 bits (147), Expect = 6e-08
Identities = 48/144 (33%), Positives = 67/144 (46%), Gaps = 9/144 (6%)
Frame = +1
Query: 190 ESPALWFTLYLFPHGKNSSNPKSIILITPFL--IHYFNRTIIYPFRLFLTTRRKKSSLSK 363
ESP + + +SS ++ L+ L +HY NRT+++P RL L +
Sbjct: 46 ESPTMCLPPLVLSAAASSSALRAAALLPGALYALHYVNRTLVHPLRLL--------RLRR 97
Query: 364 TPSGFPLSIAFMAFLFNLLNSYVQAK-WVSHYKNYDNGLCFWGV------FFGGLLVFFV 522
P+ P+ +A AF FNLLN+YVQA+ W + GL +F
Sbjct: 98 APAPVPILVAAFAFGFNLLNAYVQARSWALDAAAPHSTATATATPAAVARCLVGLALFAW 157
Query: 523 XMGINIWSDKVLLRLXGEGKGYMI 594
M NI +DK LLRL GKGY I
Sbjct: 158 GMRTNIAADKALLRLKEAGKGYQI 181
[117][TOP]
>UniRef100_C5LSN2 3-oxo-5-alpha-steroid 4-dehydrogenase, putative n=1 Tax=Perkinsus
marinus ATCC 50983 RepID=C5LSN2_9ALVE
Length = 264
Score = 61.2 bits (147), Expect = 6e-08
Identities = 49/185 (26%), Positives = 81/185 (43%), Gaps = 3/185 (1%)
Frame = +1
Query: 22 PFFQKEDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGP---NLSPPLAWFLME 192
P+ + + +YAL+ F A F+ + A YGK G+G + P + WF E
Sbjct: 7 PWIIQATRVVSYALIVGF--AAVLFVGFFGVTAAYGKMIESGYGSYSFKIDPRIGWFFQE 64
Query: 193 SPALWFTLYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPS 372
P+L + + I L++ ++HYF R+IIYP + + + RK
Sbjct: 65 LPSLLLPFLCLISEWSDLHSLQIALLSMLILHYFQRSIIYP--MLMQSHRKT-------- 114
Query: 373 GFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDK 552
P+SI AF F NS +Q+ W+ N V G ++ + + +N+ SD
Sbjct: 115 --PISIVLSAFAFCCTNSCLQSIWIRCMLNPSQISTVQLVV--GTSLYAIGLLVNLQSDY 170
Query: 553 VLLRL 567
+L L
Sbjct: 171 ILRHL 175
[118][TOP]
>UniRef100_C0PCQ2 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=C0PCQ2_MAIZE
Length = 202
Score = 60.8 bits (146), Expect = 8e-08
Identities = 48/141 (34%), Positives = 68/141 (48%), Gaps = 5/141 (3%)
Frame = +1
Query: 187 MESPALWF---TLYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSL 357
MESP LW L +P S P + + + HY +RT+++P RL + L
Sbjct: 1 MESPTLWLPPLVLLRWPPPP-LSGPLAALPAALYAFHYVHRTLVHPLRL--------ARL 51
Query: 358 SKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSHY--KNYDNGLCFWGVFFGGLLVFFVXMG 531
+ P+ PL IA A FN+LN+Y+QA+ + + + C GL +F M
Sbjct: 52 RRAPAPVPLLIAACALGFNILNAYLQARSFALHAGRQASPFRC-----LAGLALFAWGMR 106
Query: 532 INIWSDKVLLRLXGEGKGYMI 594
NI +DK LLRL G GY I
Sbjct: 107 TNIAADKELLRLKEAGGGYKI 127
[119][TOP]
>UniRef100_UPI00019258E2 PREDICTED: similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1 n=1
Tax=Hydra magnipapillata RepID=UPI00019258E2
Length = 279
Score = 60.5 bits (145), Expect = 1e-07
Identities = 56/195 (28%), Positives = 87/195 (44%), Gaps = 7/195 (3%)
Frame = +1
Query: 19 NPFFQKEDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPG--WGPNLSPPLAWFLME 192
N F Q+E + N ++F FI+ +L APYG++ G + +SP WFL E
Sbjct: 20 NLFMQREQEILNSVTTSIFTGGFIVFITTLWLPAPYGRYSYTGKLFLLPISPRFGWFLQE 79
Query: 193 SPALWFTLYLFPHG--KNSSNPKSIILITP---FLIHYFNRTIIYPFRLFLTTRRKKSSL 357
PA + NS S + +T F++HY RT Y + + KSS
Sbjct: 80 LPAFLVPCIVIGSSCLSNSQYKFSRLQLTVLGCFVLHYLIRTFYYSYNI----NGGKSS- 134
Query: 358 SKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGIN 537
PL +A F +N Y+Q++ + K+ + VF G+L+F V + IN
Sbjct: 135 -------PLIGYLLAGSFCFINGYIQSRGMLLSKSTLDDNLTRVVF--GILIFLVGLAIN 185
Query: 538 IWSDKVLLRLXGEGK 582
+ SD +L L G+
Sbjct: 186 VHSDFLLSNLRQPGE 200
[120][TOP]
>UniRef100_B1MCC7 Putative steroid dehydrogenase n=1 Tax=Mycobacterium abscessus ATCC
19977 RepID=B1MCC7_MYCA9
Length = 263
Score = 59.7 bits (143), Expect = 2e-07
Identities = 42/178 (23%), Positives = 75/178 (42%), Gaps = 2/178 (1%)
Frame = +1
Query: 40 DSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLY 219
+S+++ L F A + F Q+ YG+ G NL+P L W+LME PA L
Sbjct: 7 NSIYDTVLTAAFAFAAFVIVGGFFAQSSYGRFSTTKLGLNLNPKLGWWLMEIPATVVFLV 66
Query: 220 LFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFM 399
+ G + ++L +++HY NR +P + ++ S F +S+ M
Sbjct: 67 CYLTGPHRLETAPLVLAAIWMLHYANRGWFFPLAIRQVPGKR--------STFNVSVVVM 118
Query: 400 AFLFNLLNSYVQAKWVSH--YKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRL 567
L ++ Y+ SH + Y + F GL V+ + + S+ ++ L
Sbjct: 119 GMLVTSMHGYLNGTLFSHDFFGQYSDAWLHDPRFLLGLAVYLCGFTLLLSSESIVRNL 176
[121][TOP]
>UniRef100_UPI000155F881 PREDICTED: similar to steroid 5-alpha-reductase 2 n=1 Tax=Equus
caballus RepID=UPI000155F881
Length = 254
Score = 58.2 bits (139), Expect = 5e-07
Identities = 55/197 (27%), Positives = 83/197 (42%), Gaps = 8/197 (4%)
Frame = +1
Query: 16 QNPFFQKEDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPL--AWFLM 189
Q+P +L L L+L P + YGK+ + P AWFL
Sbjct: 7 QSPVLAGSATLAALGALVLYLAKP----------SGYGKYSESVMPAAIRLPARAAWFLQ 56
Query: 190 ESPALWFTLYLFPHGKNSSNPKSI------ILITPFLIHYFNRTIIYPFRLFLTTRRKKS 351
E P+ + P G + P+SI +L+ F HYF+RT +Y FLT R
Sbjct: 57 ELPS-----FAVPAGILARQPRSIFGQPATVLLGLFCAHYFHRTFVYS---FLTRGRP-- 106
Query: 352 SLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMG 531
FP++ F F+F + N +Q ++ + Y F G+ +F + MG
Sbjct: 107 --------FPVAFLFRGFVFCVGNGLLQGYYLVYCAEYPAEWYTDLRFSVGVFLFLLGMG 158
Query: 532 INIWSDKVLLRLXGEGK 582
INI SD +L +L G+
Sbjct: 159 INIHSDYILRQLRKPGE 175
[122][TOP]
>UniRef100_A0PSV6 Conserved hypothetical membrane protein n=1 Tax=Mycobacterium
ulcerans Agy99 RepID=A0PSV6_MYCUA
Length = 250
Score = 58.2 bits (139), Expect = 5e-07
Identities = 39/165 (23%), Positives = 70/165 (42%), Gaps = 2/165 (1%)
Frame = +1
Query: 79 IAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFPHGKNSSNPKS 258
+A I F+Q+PYG+ G NL+P L W+LME A + G +
Sbjct: 7 VAALVIIGGLFMQSPYGRFGATAGGVNLNPKLGWWLMEILATVVFAIFYLTGPQRFDAAP 66
Query: 259 IILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQA 438
++L +L+HY NR +P + ++ S F +S+ + ++ Y+
Sbjct: 67 LVLAAIWLLHYGNRGWFFPLSIRQVPGKR--------SSFNISVLAAGMVITSMHGYLNG 118
Query: 439 KWVSHYKNYDNGLCFW--GVFFGGLLVFFVXMGINIWSDKVLLRL 567
+ SH + G + F G LV+ + +WS+ ++ L
Sbjct: 119 AFFSHDYRHQYGTKWLTDPRFLLGTLVYLAGFVLLVWSESIVRNL 163
[123][TOP]
>UniRef100_UPI00017B4CF9 UPI00017B4CF9 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B4CF9
Length = 228
Score = 57.4 bits (137), Expect = 8e-07
Identities = 56/163 (34%), Positives = 72/163 (44%), Gaps = 11/163 (6%)
Frame = +1
Query: 121 PYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLF---PHGKNSSNPKSIILITP----- 276
PYG++ G G LAWFL E PA L L P + S S P
Sbjct: 2 PYGRYSSAG-GYACPAKLAWFLQEVPAFLVPLVLLLLSPESGSGSGSWSWSWSWPRLSLF 60
Query: 277 -FLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSH 453
F++HYF+R++I+ LT R PL I A +F LN ++Q + H
Sbjct: 61 AFMLHYFHRSVIF---AALTRGRP----------VPLPIVLYAAIFCSLNGFLQGHHLLH 107
Query: 454 YKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVL--LRLXGE 576
+ + L V G L+F V MGINI SD VL LR GE
Sbjct: 108 CTSAEAQL-RRAVCAAGFLLFLVGMGINIHSDHVLRSLRRPGE 149
[124][TOP]
>UniRef100_Q5YR21 Putative steroid dehydrogenase n=1 Tax=Nocardia farcinica
RepID=Q5YR21_NOCFA
Length = 263
Score = 57.4 bits (137), Expect = 8e-07
Identities = 38/131 (29%), Positives = 57/131 (43%), Gaps = 1/131 (0%)
Frame = +1
Query: 73 FLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFPHGKNSSNP 252
F A + F Q+PYG+ G NLSP L W+LME PA F G + P
Sbjct: 18 FAFAAFVIVGGLFAQSPYGRFAPASLGFNLSPKLGWWLMELPATVVFAVFFLTGPDRFEP 77
Query: 253 KSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYV 432
++L +L+HY NR +P + ++ S F +S+ L+ Y+
Sbjct: 78 VPLVLAGIWLLHYANRGWFFPLAIRQVPDKR--------STFNVSVLAAGMFVTTLHGYL 129
Query: 433 QAKWVSH-YKN 462
+ SH YK+
Sbjct: 130 NGAFFSHDYKH 140
[125][TOP]
>UniRef100_C1N6D8 Predicted protein n=1 Tax=Micromonas pusilla CCMP1545
RepID=C1N6D8_9CHLO
Length = 276
Score = 57.4 bits (137), Expect = 8e-07
Identities = 52/190 (27%), Positives = 69/190 (36%), Gaps = 27/190 (14%)
Frame = +1
Query: 91 TFISLTFLQAPYGKHHRPGWGPNLSPPLAWFLMESPALWFTLYLFPHGKNSSNPKSII-- 264
TF L F+ APYGK R GWG + L WF+ E P+ F G N ++
Sbjct: 20 TFPFLFFVSAPYGKLVRDGWGGRVDGRLGWFIQEIPSPIVLTVAFLRGANEVATDDLLTF 79
Query: 265 --------------LITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMA 402
+ + IHY NR + YP L++T S + MA
Sbjct: 80 PDAPTLPPSALTRACVAAWWIHYLNRAVRYP-------------LTRTMSDTTAPVVAMA 126
Query: 403 FLFNLLNSYVQAKWVSHYKNYD--NGLCFWGVFFGGLLVFFVXMG---------INIWSD 549
FNL A W+S YD L G +F V +G +N+ SD
Sbjct: 127 IAFNL-----GAFWLSRRSPYDRVRALAHGGAHLNDPSLFVVALGGALFLGGAALNVASD 181
Query: 550 KVLLRLXGEG 579
L L G
Sbjct: 182 STLRALRRGG 191
[126][TOP]
>UniRef100_A8J5A3 Predicted protein n=1 Tax=Chlamydomonas reinhardtii
RepID=A8J5A3_CHLRE
Length = 237
Score = 57.4 bits (137), Expect = 8e-07
Identities = 49/174 (28%), Positives = 81/174 (46%), Gaps = 3/174 (1%)
Frame = +1
Query: 82 APPTFISLTF-LQAPYGKHHRPGWGPNLSPPLAWFLMESPAL-WFTLYLFPHGKNSSNPK 255
A P F++L + APYG++ R GWG L+ +AW E P+L F + LF S+
Sbjct: 5 AVPVFLALIAGITAPYGRYVRSGWGIFLNARVAWLTQEIPSLIVFVVMLFLQHPLSAR-- 62
Query: 256 SIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQ 435
+L F HY R+I++PF + + PLS+ M+F+F + N ++Q
Sbjct: 63 -TVLSGAFCAHYVYRSIVFPF------------IIRGGKPTPLSVWAMSFVFCIWNGFIQ 109
Query: 436 AKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEGK-GYMI 594
+ D + V G + F + + + +D +L+ L G+ GY I
Sbjct: 110 GWCFARQMTSDTPVWNPRVMVGLAVWLFGWLNV-MRADLILINLRKPGESGYKI 162
[127][TOP]
>UniRef100_UPI0001866A73 hypothetical protein BRAFLDRAFT_115450 n=1 Tax=Branchiostoma
floridae RepID=UPI0001866A73
Length = 285
Score = 57.0 bits (136), Expect = 1e-06
Identities = 57/208 (27%), Positives = 87/208 (41%), Gaps = 21/208 (10%)
Frame = +1
Query: 34 KEDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHH-RPGWGPNLSPPLAWFLMESP--AL 204
+E L A + L L P FI++ F A YG++ + W L AW E P A+
Sbjct: 20 EEAFLDKLAYVMLGLSVPVFFITVFFKVAEYGRYTVKSSWA--LPARTAWLFQELPSFAV 77
Query: 205 WFTLYLFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPL 384
L LF + + +L+ F+ HYF RT I+ S L + P
Sbjct: 78 PVLLVLFGRAVRMTQLPNQVLLAMFVAHYFQRTFIF------------SLLIRGGKQTPF 125
Query: 385 SIAFMAFLFNLLNSYVQAKWVSHYKNY-----------------DNGLCFWGVFFGGLLV 513
I AF+F N Y+Q ++++ + +Y D+ L + G+ +
Sbjct: 126 HIFRDAFVFCTYNGYLQGRYLAEFAHYPDTWLSEPRCIVACSYSDDELVY--NLVAGVAM 183
Query: 514 FFVXMGINIWSDKVLLRLXGEGK-GYMI 594
F V M IN+ +D VL L G+ GY I
Sbjct: 184 FLVGMAINLHADHVLRNLRKPGETGYKI 211
[128][TOP]
>UniRef100_UPI0000D9D39A PREDICTED: steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5
alpha-steroid delta 4-dehydrogenase alpha 2) n=1
Tax=Macaca mulatta RepID=UPI0000D9D39A
Length = 254
Score = 56.2 bits (134), Expect = 2e-06
Identities = 51/198 (25%), Positives = 82/198 (41%), Gaps = 9/198 (4%)
Frame = +1
Query: 16 QNPFFQKEDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHH---RPGWGPNLSPPLAWFL 186
Q+P +L L L++ P + YGKH +P L AWFL
Sbjct: 7 QSPVLAGSATLVALGALVLYVAKP----------SGYGKHTESLKPA-ATRLPARAAWFL 55
Query: 187 MESPALWFTLYLFPHGKNSSNPKSI------ILITPFLIHYFNRTIIYPFRLFLTTRRKK 348
E P+ + P G + P S+ +L+ F +HYF+RT +Y
Sbjct: 56 QELPS-----FAVPAGILARQPLSLFGPPGTVLLGLFCVHYFHRTFVY------------ 98
Query: 349 SSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXM 528
SL +P + F F N ++Q+ ++ + Y +G F G+ +F + M
Sbjct: 99 -SLLNRGRPYPAVLIFRGIAFCAGNGFLQSYYLIYCAEYPDGWYTDIRFCLGVFLFILGM 157
Query: 529 GINIWSDKVLLRLXGEGK 582
G+NI SD +L +L G+
Sbjct: 158 GVNIHSDYILRQLRKPGE 175
[129][TOP]
>UniRef100_B8CE08 3-oxo-5-alpha-steroid 4-dehydrogenase 1-like protein (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8CE08_THAPS
Length = 180
Score = 56.2 bits (134), Expect = 2e-06
Identities = 34/108 (31%), Positives = 56/108 (51%)
Frame = +1
Query: 256 SIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQ 435
+I+L++ F +HY NR I+YP R ++ PL + A + LN Y+Q
Sbjct: 1 NILLLSLFAMHYINRAIVYPLR-----------MNPNCQPVPLVVTLSAMMVTTLNGYLQ 49
Query: 436 AKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEG 579
+ ++ + + +N C+ G+ L+FF+ MG+NI SD VL L G
Sbjct: 50 SFYLVNVEK-ENLQCWLGI-----LIFFIGMGVNIHSDGVLRNLRRYG 91
[130][TOP]
>UniRef100_B2B0K1 Predicted CDS Pa_3_5730 n=1 Tax=Podospora anserina
RepID=B2B0K1_PODAN
Length = 295
Score = 56.2 bits (134), Expect = 2e-06
Identities = 53/181 (29%), Positives = 77/181 (42%), Gaps = 12/181 (6%)
Frame = +1
Query: 52 NYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGP-NLSPPLAWFLMESPALWFTLYLF- 225
NY L+ P F SL + YG P NL LAW MESP LY F
Sbjct: 19 NYDLILSLWKWFPAFASLQWATTWYGMGKTSLPSPLNLPGRLAWLTMESPGFLTLLYTFF 78
Query: 226 ---PHGKNSSNP-KSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIA 393
P + P ++ +L F+IHY R I++P L + + LSI
Sbjct: 79 RLPPQLSVTDLPWQNSVLAGLFVIHYSYRAILFPL------------LQPSMAPMHLSIW 126
Query: 394 FMAFLFNLLNSYVQAKWVSHY-----KNYDNGLCFWGVFFG-GLLVFFVXMGINIWSDKV 555
AF F ++N + W+ Y +++DN L F + F G+ +F+V + N + D
Sbjct: 127 ASAFSFQVINGLMLGSWLGGYGPTSQEDWDNLLPFGTLQFSVGIAIFYVGLAANYYHDDE 186
Query: 556 L 558
L
Sbjct: 187 L 187
[131][TOP]
>UniRef100_Q28892 3-oxo-5-alpha-steroid 4-dehydrogenase 2 n=1 Tax=Macaca fascicularis
RepID=S5A2_MACFA
Length = 254
Score = 56.2 bits (134), Expect = 2e-06
Identities = 51/198 (25%), Positives = 82/198 (41%), Gaps = 9/198 (4%)
Frame = +1
Query: 16 QNPFFQKEDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHH---RPGWGPNLSPPLAWFL 186
Q+P +L L L++ P + YGKH +P L AWFL
Sbjct: 7 QSPVLAGSATLVALGALVLYVAKP----------SGYGKHTESLKPA-ATRLPARAAWFL 55
Query: 187 MESPALWFTLYLFPHGKNSSNPKSI------ILITPFLIHYFNRTIIYPFRLFLTTRRKK 348
E P+ + P G + P S+ +L+ F +HYF+RT +Y
Sbjct: 56 QELPS-----FAVPAGILARQPLSLFGPPGTVLLGLFCVHYFHRTFVY------------ 98
Query: 349 SSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXM 528
SL +P + F F N ++Q+ ++ + Y +G F G+ +F + M
Sbjct: 99 -SLLNRGRPYPAVLIFRGIAFCAGNGFLQSYYLIYCAEYPDGWYTDIRFCLGVFLFILGM 157
Query: 529 GINIWSDKVLLRLXGEGK 582
G+NI SD +L +L G+
Sbjct: 158 GVNIHSDYILRQLRKPGE 175
[132][TOP]
>UniRef100_P31214 3-oxo-5-alpha-steroid 4-dehydrogenase 2 n=1 Tax=Rattus norvegicus
RepID=S5A2_RAT
Length = 254
Score = 55.5 bits (132), Expect = 3e-06
Identities = 56/193 (29%), Positives = 77/193 (39%), Gaps = 3/193 (1%)
Frame = +1
Query: 13 HQNPFFQKEDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRP--GWGPNLSPPLAWFL 186
HQ P +L L L L P A YGKH P L +AWFL
Sbjct: 6 HQVPVLAGSATLATMGTLILCLGKP----------ASYGKHTESVSSGVPFLPARIAWFL 55
Query: 187 MESPALWFTLYLFPHGKNSS-NPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSK 363
E P+ ++ + S P +L+ F HYF+RT IY L TR +
Sbjct: 56 QELPSFVVSVGMLAWQPRSLFGPPGNVLLALFSAHYFHRTFIYS----LLTRGRP----- 106
Query: 364 TPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIW 543
FP + A F + N +QA ++ + Y F G+ +F + MGINI
Sbjct: 107 ----FPAVLFLRATAFCIGNGLLQAYYLVYCAEYPEEWYTDVRFSFGVFLFILGMGINIH 162
Query: 544 SDKVLLRLXGEGK 582
SD L +L G+
Sbjct: 163 SDYTLRQLRKPGE 175
[133][TOP]
>UniRef100_UPI0000D9B3A3 PREDICTED: similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1
(Steroid 5-alpha-reductase 1) (SR type 1) (S5AR) isoform
1 n=1 Tax=Macaca mulatta RepID=UPI0000D9B3A3
Length = 215
Score = 54.7 bits (130), Expect = 5e-06
Identities = 40/126 (31%), Positives = 60/126 (47%), Gaps = 1/126 (0%)
Frame = +1
Query: 220 LFPHGKNSSNPKSIILITPFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFM 399
+FP +++ N IL+ FL+HY +R +IYPF L + PL M
Sbjct: 31 VFPRLRSAPN---CILLAMFLVHYGHRCLIYPF------------LMRGGKPMPLLACTM 75
Query: 400 AFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLLRLXGEG 579
A +F N Y+Q++++SH+ Y + F G ++ M INI SD +L L G
Sbjct: 76 AIMFCTFNGYLQSRYLSHWAVYADDWVTDPRFLIGFGLWLAGMLINIHSDHILRNLRKPG 135
Query: 580 -KGYMI 594
GY I
Sbjct: 136 DTGYKI 141
[134][TOP]
>UniRef100_A8XFC5 Putative uncharacterized protein n=1 Tax=Caenorhabditis briggsae
RepID=A8XFC5_CAEBR
Length = 254
Score = 54.7 bits (130), Expect = 5e-06
Identities = 44/157 (28%), Positives = 70/157 (44%), Gaps = 2/157 (1%)
Frame = +1
Query: 97 ISLTFLQAPYGKHHRPGWGPNLSPP-LAWFLMESPALWFTLYLFPHGKNSSNPKSIILIT 273
+S T A YG++ P ++ P LAW ESPA + Y + ++ + L
Sbjct: 24 LSNTGKPAEYGRYSNPSPSKSMIPAKLAWMTQESPAFFIPFYFYWTDQHLTE-YGKFLTC 82
Query: 274 PFLIHYFNRTIIYPFRLFLTTRRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSH 453
FL +Y RT YP L ++ + P I M FLF + N ++Q W ++
Sbjct: 83 VFLFYYAYRTFAYPL------------LIRSKNETPFEIVLMKFLFCIFNGFIQGSWNAY 130
Query: 454 YK-NYDNGLCFWGVFFGGLLVFFVXMGINIWSDKVLL 561
Y+ D + VFF G+ +F + I+ SD L+
Sbjct: 131 YQPEIDKFHPRFFVFF-GIWLFVIGFIIHCISDLHLI 166
[135][TOP]
>UniRef100_O18765 3-oxo-5-alpha-steroid 4-dehydrogenase 2 n=1 Tax=Sus scrofa
RepID=S5A2_PIG
Length = 254
Score = 54.3 bits (129), Expect = 7e-06
Identities = 42/142 (29%), Positives = 66/142 (46%), Gaps = 6/142 (4%)
Frame = +1
Query: 175 AWFLMESPALWFTLYLFPHGKNSSNPKSI------ILITPFLIHYFNRTIIYPFRLFLTT 336
AWFL E P+ ++ P G + P+S+ +L+ F HYF+RT +Y L T
Sbjct: 52 AWFLQELPS-----FVVPAGILAGQPRSLFGPPATVLLGLFCAHYFHRTFVYS----LLT 102
Query: 337 RRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVF 516
R + FP+ F F+F + N +Q ++ + Y F G+ +F
Sbjct: 103 RGRP---------FPVVFLFRGFVFCMGNGLLQGYYLVYCAEYPAEWYTDIRFSLGVFLF 153
Query: 517 FVXMGINIWSDKVLLRLXGEGK 582
+ MGINI SD +L +L G+
Sbjct: 154 ILGMGINIHSDYILRQLRKPGE 175
[136][TOP]
>UniRef100_UPI00005BF517 PREDICTED: similar to steroid 5-alpha-reductase 2 n=1 Tax=Bos
taurus RepID=UPI00005BF517
Length = 254
Score = 53.9 bits (128), Expect = 9e-06
Identities = 55/202 (27%), Positives = 82/202 (40%), Gaps = 13/202 (6%)
Frame = +1
Query: 16 QNPFFQKEDSLFNYALLTLFLIAPPTFISLTFLQAPYGKHHRPGWGPNLSPPL------- 174
Q+P +L L L+L P + YGK+ NL P
Sbjct: 7 QSPVLAGSATLAALGALVLYLAEP----------SGYGKYSE-----NLMPVAIRLPARA 51
Query: 175 AWFLMESPALWFTLYLFPHGKNSSNPKSI------ILITPFLIHYFNRTIIYPFRLFLTT 336
AWFL E P+ + P G + P S+ +L+ F HYF+RT +Y L T
Sbjct: 52 AWFLQELPS-----FAVPAGILAGQPSSLLGPPATVLLGLFCAHYFHRTFVYS----LLT 102
Query: 337 RRKKSSLSKTPSGFPLSIAFMAFLFNLLNSYVQAKWVSHYKNYDNGLCFWGVFFGGLLVF 516
R + FP+ F F+F + N +Q ++ + Y F G+ +F
Sbjct: 103 RGRP---------FPVVFLFRGFVFCMGNGLLQGYYLVYCAEYPAEWYTDIRFSLGIFLF 153
Query: 517 FVXMGINIWSDKVLLRLXGEGK 582
+ MGINI SD +L +L G+
Sbjct: 154 ILGMGINIHSDYILRQLRKPGE 175