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[1][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 350 bits (897), Expect = 6e-95
Identities = 159/191 (83%), Positives = 177/191 (92%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FWANRPKSY++RTIGWDQYPHGRWGDS NPSYGAL+DYQFMRPRA+ KKL+EEWA PLKS
Sbjct: 342 FWANRPKSYLTRTIGWDQYPHGRWGDSRNPSYGALSDYQFMRPRARGKKLLEEWAAPLKS 401
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
VEDIYE+F+++CLGKL+++PWSELDGLQPETKIINE L KIN KGFLTINSQPAVNGEKS
Sbjct: 402 VEDIYEKFKVYCLGKLKSSPWSELDGLQPETKIINEQLGKINLKGFLTINSQPAVNGEKS 461
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
DSP+VGWGGPGGYVYQKAYLEFFCSK+KL+ALV+K K PF+TY+AVNK G W SNV T
Sbjct: 462 DSPSVGWGGPGGYVYQKAYLEFFCSKDKLNALVDKCKSFPFVTYIAVNKGGSWISNVALT 521
Query: 541 DVNAVTWGVFP 573
DVNAVTWGVFP
Sbjct: 522 DVNAVTWGVFP 532
[2][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 344 bits (883), Expect = 2e-93
Identities = 158/192 (82%), Positives = 175/192 (91%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FWANRPKSY+SRTIGWDQYPHGRWGDS NPSYGAL+DYQFMRPRA+ KKL EEWA PLKS
Sbjct: 345 FWANRPKSYLSRTIGWDQYPHGRWGDSHNPSYGALSDYQFMRPRARGKKLFEEWASPLKS 404
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
VEDIYE+F+++CLGKL+++PWSEL+GLQPETKIINE L +IN KGFLTINSQPAVN EKS
Sbjct: 405 VEDIYEKFKVYCLGKLKSSPWSELEGLQPETKIINEQLGRINLKGFLTINSQPAVNAEKS 464
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
DSP+VGWGGPGGYVYQKAYLEFFCSKEKL+ALVE+ K P +TYMAVN+ G W SNV T
Sbjct: 465 DSPSVGWGGPGGYVYQKAYLEFFCSKEKLNALVERCKAFPLVTYMAVNRGGSWISNVALT 524
Query: 541 DVNAVTWGVFPA 576
DVNAVTWGVFPA
Sbjct: 525 DVNAVTWGVFPA 536
[3][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 340 bits (871), Expect = 6e-92
Identities = 157/192 (81%), Positives = 172/192 (89%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FWANRP+SYISRTIGWDQYPHGRW DS NPSYG LTDYQFMRPRA+DKKL +EW VPLKS
Sbjct: 331 FWANRPRSYISRTIGWDQYPHGRWSDSCNPSYGGLTDYQFMRPRARDKKLQDEWVVPLKS 390
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+ED+ ERF FCLGKL+++PWSELDGLQPE+KIINE L IN+KGFLTINSQPAVNGEKS
Sbjct: 391 IEDVQERFIKFCLGKLKSSPWSELDGLQPESKIINELLGNINSKGFLTINSQPAVNGEKS 450
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
DS +VGWGGPGGYVYQKAYLEFFCS+EKL+ALV+K K P LTYMAVNKEG W SNVG
Sbjct: 451 DSLSVGWGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHPSLTYMAVNKEGTWMSNVGPG 510
Query: 541 DVNAVTWGVFPA 576
+VNAVTWGVFPA
Sbjct: 511 EVNAVTWGVFPA 522
[4][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 337 bits (863), Expect = 5e-91
Identities = 156/192 (81%), Positives = 171/192 (89%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FWANRP+SYISRTIGWDQYPHGRW DS NPSYG LTDYQFMRPRA+DKKL +EW VPLKS
Sbjct: 331 FWANRPRSYISRTIGWDQYPHGRWSDSCNPSYGGLTDYQFMRPRARDKKLQDEWVVPLKS 390
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+ED+ ERF FCLGKL+++PWSELDGLQPE+KIINE L IN+KGFLTINSQPAVNGEKS
Sbjct: 391 IEDVQERFIKFCLGKLKSSPWSELDGLQPESKIINELLGNINSKGFLTINSQPAVNGEKS 450
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
DS +VGWGGPGGYVYQKAYLEFFCS+EKL+ALV+K K LTYMAVNKEG W SNVG
Sbjct: 451 DSLSVGWGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHTSLTYMAVNKEGTWMSNVGPG 510
Query: 541 DVNAVTWGVFPA 576
+VNAVTWGVFPA
Sbjct: 511 EVNAVTWGVFPA 522
[5][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 337 bits (863), Expect = 5e-91
Identities = 156/192 (81%), Positives = 171/192 (89%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FWANRP+SYISRTIGWDQYPHGRW DS NPSYG LTDYQFMRPRA+DKKL +EW VPLKS
Sbjct: 324 FWANRPRSYISRTIGWDQYPHGRWSDSCNPSYGGLTDYQFMRPRARDKKLQDEWVVPLKS 383
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+ED+ ERF FCLGKL+++PWSELDGLQPE+KIINE L IN+KGFLTINSQPAVNGEKS
Sbjct: 384 IEDVQERFIKFCLGKLKSSPWSELDGLQPESKIINELLGNINSKGFLTINSQPAVNGEKS 443
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
DS +VGWGGPGGYVYQKAYLEFFCS+EKL+ALV+K K LTYMAVNKEG W SNVG
Sbjct: 444 DSLSVGWGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHTSLTYMAVNKEGTWMSNVGPG 503
Query: 541 DVNAVTWGVFPA 576
+VNAVTWGVFPA
Sbjct: 504 EVNAVTWGVFPA 515
[6][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 331 bits (848), Expect = 3e-89
Identities = 153/191 (80%), Positives = 169/191 (88%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FWANRPKSYISRT+GW+QYP GRWGDS NPSYGAL+D+QFMRPRA+DKKL +EW VPL S
Sbjct: 346 FWANRPKSYISRTLGWEQYPQGRWGDSCNPSYGALSDHQFMRPRARDKKLHDEWVVPLSS 405
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
EDI+E+F+ CLGKL+T+PWSELDGLQPETKIINE L KIN KGFLTINSQPAVNGEKS
Sbjct: 406 AEDIFEKFKKHCLGKLKTSPWSELDGLQPETKIINEQLGKINLKGFLTINSQPAVNGEKS 465
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
DSP+VGWGGPGGYVYQKAY+EFFCS +KL AL+EK K P LTYMAVN+ G SNVGQ
Sbjct: 466 DSPSVGWGGPGGYVYQKAYIEFFCSTDKLQALLEKCKALPQLTYMAVNRGGTLLSNVGQN 525
Query: 541 DVNAVTWGVFP 573
DVNAVTWGVFP
Sbjct: 526 DVNAVTWGVFP 536
[7][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 324 bits (831), Expect = 3e-87
Identities = 152/191 (79%), Positives = 165/191 (86%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FWANRPKSY+ RT+GWDQYPHGRWGDS NPSYGALTD+QF RPR + KKL EEWAVPLKS
Sbjct: 331 FWANRPKSYLKRTLGWDQYPHGRWGDSRNPSYGALTDHQFTRPRGRGKKLQEEWAVPLKS 390
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
VEDI ERF FC GKL ++PWSELDGLQPETKII++ L KIN KGFLTINSQPAVNGEKS
Sbjct: 391 VEDISERFTNFCQGKLTSSPWSELDGLQPETKIIDDQLVKINQKGFLTINSQPAVNGEKS 450
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
DSPTVGWGGPGGYVYQKAYLEFFC+KEKLD L+EK K P LTY+AVNK+G SN+
Sbjct: 451 DSPTVGWGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKAFPSLTYIAVNKDGESFSNIAPN 510
Query: 541 DVNAVTWGVFP 573
VNAVTWGVFP
Sbjct: 511 AVNAVTWGVFP 521
[8][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 323 bits (827), Expect = 8e-87
Identities = 152/191 (79%), Positives = 166/191 (86%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FWANRPKSYISRT+GWDQYPHGRWGDS NPSYGALTDYQF RPR + KKL EEWAVP+KS
Sbjct: 331 FWANRPKSYISRTLGWDQYPHGRWGDSRNPSYGALTDYQFTRPRGRGKKLQEEWAVPVKS 390
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
VEDI ERF FC GKL ++PWSELDGLQPETKII++ L KIN KGFLTINSQPAVNGE+S
Sbjct: 391 VEDINERFMNFCQGKLTSSPWSELDGLQPETKIIDDQLVKINQKGFLTINSQPAVNGERS 450
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
DS +VGWGGPGGYVYQKAYLEFFCSKEKLD L+EK+K P LTY+AVNK+G SN+
Sbjct: 451 DSTSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIAVNKDGESFSNIPTN 510
Query: 541 DVNAVTWGVFP 573
VNAVTWGVFP
Sbjct: 511 AVNAVTWGVFP 521
[9][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 323 bits (827), Expect = 8e-87
Identities = 152/191 (79%), Positives = 166/191 (86%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FWANRPKSYISRT+GWDQYPHGRWGDS NPSYGALTDYQF RPR + KKL EEWAVP+KS
Sbjct: 331 FWANRPKSYISRTLGWDQYPHGRWGDSRNPSYGALTDYQFTRPRGRGKKLQEEWAVPVKS 390
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
VEDI ERF FC GKL ++PWSELDGLQPETKII++ L KIN KGFLTINSQPAVNGE+S
Sbjct: 391 VEDINERFMNFCQGKLTSSPWSELDGLQPETKIIDDQLVKINQKGFLTINSQPAVNGERS 450
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
DS +VGWGGPGGYVYQKAYLEFFCSKEKLD L+EK+K P LTY+AVNK+G SN+
Sbjct: 451 DSTSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIAVNKDGESFSNIPTN 510
Query: 541 DVNAVTWGVFP 573
VNAVTWGVFP
Sbjct: 511 AVNAVTWGVFP 521
[10][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 323 bits (827), Expect = 8e-87
Identities = 151/191 (79%), Positives = 164/191 (85%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FWANRPKSY+ RT+GWDQYPHGRWGDS NPSYGALTD+QF RPR + KKL EEWAVPLKS
Sbjct: 331 FWANRPKSYLKRTLGWDQYPHGRWGDSRNPSYGALTDHQFTRPRGRGKKLQEEWAVPLKS 390
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
VEDI ERF FC GKL ++PWSELDGLQPETKII++ L IN KGFLTINSQPAVNGEKS
Sbjct: 391 VEDISERFTNFCQGKLTSSPWSELDGLQPETKIIDDQLVNINQKGFLTINSQPAVNGEKS 450
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
DSPTVGWGGPGGYVYQKAYLEFFC+KEKLD L+EK K P LTY+AVNK+G SN+
Sbjct: 451 DSPTVGWGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKAFPSLTYIAVNKDGETFSNISPN 510
Query: 541 DVNAVTWGVFP 573
VNAVTWGVFP
Sbjct: 511 AVNAVTWGVFP 521
[11][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 315 bits (808), Expect = 1e-84
Identities = 146/192 (76%), Positives = 165/192 (85%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FWANRPKSYISRT GW+ +P GRWGDS + SYGAL+D+QF RPRA+DKKL +EW VPLKS
Sbjct: 331 FWANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKS 390
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
VEDI E+F+ CLG L+++PWSELDGLQPET+IINE L K+N+KGFLTINSQP+VN E+S
Sbjct: 391 VEDIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERS 450
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
DSPTVGWGGP GYVYQKAYLEFFCSKEKLDA+VEK K P +TYMAVNK W SN Q
Sbjct: 451 DSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQA 510
Query: 541 DVNAVTWGVFPA 576
DVNAVTWGVFPA
Sbjct: 511 DVNAVTWGVFPA 522
[12][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 313 bits (801), Expect = 8e-84
Identities = 147/191 (76%), Positives = 164/191 (85%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FWANRPKSYISRT GWDQYPHGRWGDS NPSYGAL D+QF RPR + KKL EEWAVPLKS
Sbjct: 319 FWANRPKSYISRTTGWDQYPHGRWGDSRNPSYGALNDHQFTRPRGRGKKLQEEWAVPLKS 378
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
V+DI ERF FC GKL+++PWSELDGLQPET II++ L KIN+KGFLTINSQPAVN EKS
Sbjct: 379 VQDINERFVNFCEGKLKSSPWSELDGLQPETTIIDDQLVKINSKGFLTINSQPAVNAEKS 438
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
+SP+VGWGGPGGYVYQKAY+EFFC+KEKL L+EK+K P LTY+AVNKEG SN+
Sbjct: 439 ESPSVGWGGPGGYVYQKAYVEFFCAKEKLGQLIEKSKAFPSLTYIAVNKEGESISNIPAN 498
Query: 541 DVNAVTWGVFP 573
VNAVTWGVFP
Sbjct: 499 AVNAVTWGVFP 509
[13][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 312 bits (800), Expect = 1e-83
Identities = 139/192 (72%), Positives = 168/192 (87%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FWANRP+SYISRTIGW+Q+P+GRWGD+ +P+YGAL DYQF+R R++ KK++EEW VPL S
Sbjct: 331 FWANRPRSYISRTIGWEQFPNGRWGDARSPAYGALNDYQFLRRRSRSKKILEEWVVPLSS 390
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+ DI E+F FC+GKL++NPWSELDGLQPET INE LE++N KGFLTINSQPAVNGEKS
Sbjct: 391 IVDIQEKFANFCVGKLKSNPWSELDGLQPETVKINEKLEQLNRKGFLTINSQPAVNGEKS 450
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
DSP++GWGG GYVYQKAY+EFFCS EKL+ LVEK K+ PF+TY+AVNK+G +N+G T
Sbjct: 451 DSPSIGWGGAAGYVYQKAYVEFFCSPEKLNELVEKAKNLPFVTYIAVNKKGATAANIGPT 510
Query: 541 DVNAVTWGVFPA 576
DVNAVTWGVFPA
Sbjct: 511 DVNAVTWGVFPA 522
[14][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=B9DHL6_ARATH
Length = 402
Score = 311 bits (798), Expect = 2e-83
Identities = 139/192 (72%), Positives = 163/192 (84%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FWANRPKSYISRT GW+ +PHGRWGDS + +Y L+DYQF RP+ +DKKL +EW VPLKS
Sbjct: 141 FWANRPKSYISRTKGWNDFPHGRWGDSHSAAYSTLSDYQFARPKGRDKKLQQEWVVPLKS 200
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+ED+ E+F+ C+G L+++PWSELDGLQPETKIINE L KIN+ GFLTINSQP+VN KS
Sbjct: 201 IEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKS 260
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
DSP +GWGGPGGYVYQKAYLEFFCSK+KLD LVEK+K P +TYMAVNK W SN G++
Sbjct: 261 DSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGES 320
Query: 541 DVNAVTWGVFPA 576
DVNAVTWGVFPA
Sbjct: 321 DVNAVTWGVFPA 332
[15][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 311 bits (798), Expect = 2e-83
Identities = 139/192 (72%), Positives = 163/192 (84%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FWANRPKSYISRT GW+ +PHGRWGDS + +Y L+DYQF RP+ +DKKL +EW VPLKS
Sbjct: 331 FWANRPKSYISRTKGWNDFPHGRWGDSHSAAYSTLSDYQFARPKGRDKKLQQEWVVPLKS 390
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+ED+ E+F+ C+G L+++PWSELDGLQPETKIINE L KIN+ GFLTINSQP+VN KS
Sbjct: 391 IEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKS 450
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
DSP +GWGGPGGYVYQKAYLEFFCSK+KLD LVEK+K P +TYMAVNK W SN G++
Sbjct: 451 DSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGES 510
Query: 541 DVNAVTWGVFPA 576
DVNAVTWGVFPA
Sbjct: 511 DVNAVTWGVFPA 522
[16][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 290 bits (741), Expect = 7e-77
Identities = 129/192 (67%), Positives = 158/192 (82%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FWANRP+SYISRT WD++P GRWGD+GNP+YG+ +D+QF+R + + KKL +EWAVPL S
Sbjct: 331 FWANRPRSYISRTTSWDEFPRGRWGDTGNPAYGSFSDHQFLRKKTRSKKLQKEWAVPLNS 390
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
ED+ + F +C G L T+PWSEL+GLQPET IN+ L +NT+GFLTINSQPAVNGEKS
Sbjct: 391 CEDVNQIFAKYCQGTLSTHPWSELEGLQPETSQINDKLVALNTQGFLTINSQPAVNGEKS 450
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
DSP+VGWGGPGGYVYQKAY+EFFCS EKL A++EK K P LT++AVN +G +SN+G
Sbjct: 451 DSPSVGWGGPGGYVYQKAYVEFFCSPEKLQAVIEKAKSNPSLTFIAVNAKGETQSNIGPN 510
Query: 541 DVNAVTWGVFPA 576
VNAVTWGVFPA
Sbjct: 511 CVNAVTWGVFPA 522
[17][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 286 bits (733), Expect = 6e-76
Identities = 132/192 (68%), Positives = 153/192 (79%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FWANRP+SYISRT WD +P GRWGD+ NP+YG+ +D+QF R + + KKL +EWAVPL S
Sbjct: 331 FWANRPRSYISRTTSWDDFPRGRWGDTANPAYGSFSDHQFTRKKTRSKKLQKEWAVPLNS 390
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
ED+ F +C G L T+PWSEL+GLQPET INE L +N GFLTINSQPAVNGEKS
Sbjct: 391 SEDVNAIFAKYCQGTLSTHPWSELEGLQPETVQINEKLVALNQGGFLTINSQPAVNGEKS 450
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
DSP+VGWGGPGGYVYQKAY+EFFCS EKL A++EK K P LTY+AVN +G KSNVG T
Sbjct: 451 DSPSVGWGGPGGYVYQKAYVEFFCSPEKLQAVIEKAKTSPSLTYIAVNAKGETKSNVGPT 510
Query: 541 DVNAVTWGVFPA 576
VNAVTWGVFPA
Sbjct: 511 SVNAVTWGVFPA 522
[18][TOP]
>UniRef100_A9P8D1 Putative uncharacterized protein n=1 Tax=Populus trichocarpa
RepID=A9P8D1_POPTR
Length = 224
Score = 265 bits (676), Expect = 2e-69
Identities = 123/151 (81%), Positives = 138/151 (91%)
Frame = +1
Query: 121 MRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEK 300
MRPRA+ KKL+EEWA PLKSVEDIYE+F+++CLGKL+++PWSELDGLQPETKIINE L K
Sbjct: 1 MRPRARGKKLLEEWAAPLKSVEDIYEKFKVYCLGKLKSSPWSELDGLQPETKIINEQLGK 60
Query: 301 INTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRP 480
IN KGFLTINSQPAVNGEKSDSP+VGWGGPGGYVYQKAYLEFFCSK+KL+ALV+K K P
Sbjct: 61 INLKGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYLEFFCSKDKLNALVDKCKSFP 120
Query: 481 FLTYMAVNKEGVWKSNVGQTDVNAVTWGVFP 573
F+TY+AVNK G W SNV TDVNAVTWGVFP
Sbjct: 121 FVTYIAVNKGGSWISNVALTDVNAVTWGVFP 151
[19][TOP]
>UniRef100_A6N158 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Oryza sativa
Indica Group RepID=A6N158_ORYSI
Length = 237
Score = 261 bits (666), Expect = 4e-68
Identities = 126/163 (77%), Positives = 139/163 (85%)
Frame = +1
Query: 85 NPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQ 264
NPSYGALTDYQF RPR + KKL EEWAVP+KSVEDI ERF FC GKL ++PWSELDGLQ
Sbjct: 2 NPSYGALTDYQFTRPRGRGKKLQEEWAVPVKSVEDINERFMNFCQGKLTSSPWSELDGLQ 61
Query: 265 PETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 444
PETKII++ L KIN KGFLTINSQPAVNGE+SDS +VGWGGPGGYVYQKAYLEFFCSKEK
Sbjct: 62 PETKIIDDQLVKINQKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEK 121
Query: 445 LDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFP 573
LD L+EK+K P LTY+AVNK+G SN+ VNAVTWGVFP
Sbjct: 122 LDQLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVFP 164
[20][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 194 bits (492), Expect = 5e-48
Identities = 97/196 (49%), Positives = 121/196 (61%), Gaps = 5/196 (2%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPR----AKDKKLIEEWAV 168
FW+NRPK+Y+ RT WD YP GRWG++ +P+YGAL+D+QFMR A+ +K W
Sbjct: 327 FWSNRPKAYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHSTGEARREKARAAWGA 386
Query: 169 PLKSVEDIYERFRLFCLGKLRTNPWSELDG-LQPETKIINEHLEKINTKGFLTINSQPAV 345
SV+D+ + F + G++ PW+ELDG L E I E L +N G+LTINSQP V
Sbjct: 387 APASVDDVKQVFVKYIKGEVSLLPWAELDGGLTAEAAAIREPLAALNANGYLTINSQPRV 446
Query: 346 NGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKS 525
NG SD GWGGPGGYVY KAY+EFFCS E L K P +TY+A G
Sbjct: 447 NGVASDDAVHGWGGPGGYVYGKAYVEFFCSPEAWATLRAKLDAAPSITYLATTAAGSPAG 506
Query: 526 NVGQTDVNAVTWGVFP 573
N+ VNAVTWGVFP
Sbjct: 507 NMAPDAVNAVTWGVFP 522
[21][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 191 bits (484), Expect = 5e-47
Identities = 93/191 (48%), Positives = 128/191 (67%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FWANR KSY++RT WD++P+GRWGD+ +P+YG + Y ++ R +++ E W P
Sbjct: 341 FWANRAKSYVNRTETWDEFPNGRWGDARSPAYGDVDAYG-VKLRYSNEEAKEMWGAPT-C 398
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
++D+ F+ FC G+++ PWSE + ET +I++ L K+N GFLTINSQPAV+G +S
Sbjct: 399 LDDVKTLFQQFCAGQVKALPWSETP-VARETSVISDKLAKMNQLGFLTINSQPAVDGARS 457
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
D GWG GYVYQKAYLEFF S E LDAL+ + + P +TY AVN +G ++N
Sbjct: 458 DDKVHGWGPKNGYVYQKAYLEFFVSPEDLDALIARIEADPQITYHAVNSQGDMRTNTNSE 517
Query: 541 DVNAVTWGVFP 573
NAVTWGVFP
Sbjct: 518 APNAVTWGVFP 528
[22][TOP]
>UniRef100_A8Q9P3 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8Q9P3_MALGO
Length = 515
Score = 186 bits (472), Expect = 1e-45
Identities = 93/193 (48%), Positives = 122/193 (63%), Gaps = 2/193 (1%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRP--RAKDKKLIEEWAVPL 174
FWANR KSYI RT WD++P+GRWGD+ +P+YG D P R ++ ++ W P
Sbjct: 250 FWANRAKSYIDRTDAWDEFPNGRWGDARSPAYG---DADVFGPYLRQTKEEALDLWGSPT 306
Query: 175 KSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGE 354
+++D+ F FC G+L PWS+ L ET +INE L +N +GF TINSQPAV+G
Sbjct: 307 -TIQDLQSLFARFCTGELACLPWSDAP-LAKETSVINEPLRALNERGFFTINSQPAVDGA 364
Query: 355 KSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVG 534
+SD P GWG GYVYQKAYLEFF S ++LD L+ + P +TY AVN +G ++N
Sbjct: 365 RSDDPVHGWGPKHGYVYQKAYLEFFVSPQQLDELIARFDAHPQITYHAVNAQGDMRTNTT 424
Query: 535 QTDVNAVTWGVFP 573
NAVTWG FP
Sbjct: 425 SDAPNAVTWGCFP 437
[23][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 184 bits (468), Expect = 3e-45
Identities = 94/201 (46%), Positives = 125/201 (62%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKK--LIEEWAVPL 174
FWA+RPKSYI RT WD +P+GRWG+S +P++G LTDY ++K K L++ W L
Sbjct: 366 FWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQMWGEEL 425
Query: 175 KSVEDIYERFRLFCLG-------KLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E +YE F + G K+ PW++ D L PET ++ + LEK+N +G LTINS
Sbjct: 426 MSEESVYEVFTNYITGQTNRSGHKVMCLPWND-DPLAPETNLLKDELEKVNRRGVLTINS 484
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD-RPFLTYMAVNKE 510
QP +NG+ S VGWG GGYV+QKAYLEFF S E + AL++ K P + Y VN +
Sbjct: 485 QPNINGKASSDAIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYQIVNVQ 544
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N NAVTWG+FP
Sbjct: 545 GRNITNAHDMQPNAVTWGIFP 565
[24][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 184 bits (467), Expect = 4e-45
Identities = 97/201 (48%), Positives = 124/201 (61%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSY+ RT+ WD+YP+GRWG S +P++G L DY +++ +K +L++ W L
Sbjct: 350 FWASRPKSYVHRTMMWDEYPNGRWGSSASPAFGELKDYHIFYLKNTSKKDELLKMWGEKL 409
Query: 175 KSVEDIYERFRLFCLG-------KLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINS 333
+SVED+YE F F G K+ PWS D L ET I + LE IN+KG LTINS
Sbjct: 410 ESVEDVYEIFTCFVSGERNKYGYKVDALPWSN-DALALETLFIKKSLEYINSKGILTINS 468
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVN-KE 510
QP VN S GWGGP GYVYQKAYLEFF S E+ L+E + P + Y A++ E
Sbjct: 469 QPNVNALPSTHEVFGWGGPNGYVYQKAYLEFFISAERFKTLLEVLPNFPMINYHALDLSE 528
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
+ SN AVTWGVFP
Sbjct: 529 SINVSNSDHHQPIAVTWGVFP 549
[25][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 183 bits (464), Expect = 9e-45
Identities = 98/195 (50%), Positives = 122/195 (62%), Gaps = 4/195 (2%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQF-MRPRAKDKKLIEEWAVPLK 177
FWANR +SY+SRT WD++P+GRWGDS +P+YG L Y + A D + W P
Sbjct: 329 FWANRTRSYLSRTADWDEFPNGRWGDSRSPAYGDLDGYPVSIGITAPDAYNL--WGHPTT 386
Query: 178 SVEDIYERFRLFCLGKLRTNPWSELDGLQP---ETKIINEHLEKINTKGFLTINSQPAVN 348
S D++ F FC G L PWS QP ET +I E L K+N G+LTINSQPAV+
Sbjct: 387 S-SDLHALFARFCRGDLAKLPWST----QPPASETSLIIEQLAKMNELGYLTINSQPAVD 441
Query: 349 GEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSN 528
G +SD GWG PGGYVYQKAYLEFF S + L L+ + + P +TY AVNK+G ++N
Sbjct: 442 GVRSDDKVHGWGPPGGYVYQKAYLEFFVSPDLLSPLIRRIEKDPRITYYAVNKQGDLRTN 501
Query: 529 VGQTDVNAVTWGVFP 573
NAVTWGVFP
Sbjct: 502 THSESPNAVTWGVFP 516
[26][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 181 bits (459), Expect = 4e-44
Identities = 90/201 (44%), Positives = 126/201 (62%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L
Sbjct: 360 FWASRPKSYIHRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGQEL 419
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F + G+ N PW++ D L PET ++ L+K+N +G LTINS
Sbjct: 420 NSEESVFEVFTYYISGEPNPNGHKVNCLPWND-DPLAPETNLLKNELQKVNKRGILTINS 478
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD-RPFLTYMAVNKE 510
QP VNG+ S P VGWG GYV+QKAYLEFF S E + AL++ K P + Y VN
Sbjct: 479 QPNVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEMVSALIKVLKRYEPRVNYHIVNVH 538
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N NAVTWG+FP
Sbjct: 539 GQNITNAADLQPNAVTWGIFP 559
[27][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 180 bits (456), Expect = 8e-44
Identities = 92/201 (45%), Positives = 126/201 (62%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSY+ RT WD++P+GRWG S +P++G L DY +++P AK ++L++ W L
Sbjct: 355 FWASRPKSYVYRTQEWDEFPNGRWGSSESPAFGELNDYYLFYLKPNAKKEELLDMWGHEL 414
Query: 175 KSVEDIYERFRLFCLGK-------LRTNPWSELDGLQPETKIINEHLEKINTKGFLTINS 333
++D+ + F + GK +R PW++ D L ET IN+ L +IN++G LTINS
Sbjct: 415 TCLQDVCDVFTNYITGKESKNGKKVRKIPWND-DDLAAETSFINDKLARINSRGVLTINS 473
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEG 513
QP VN S P VGWG PGGYV+QKAYLEFF S+E + AL + P + Y + EG
Sbjct: 474 QPNVNAAPSTDPVVGWGTPGGYVFQKAYLEFFTSRENVQALFKVLPKYPNVNYHIIKFEG 533
Query: 514 VWK-SNVGQTDVNAVTWGVFP 573
+N Q AVTWGVFP
Sbjct: 534 DDDYTNCDQQQPIAVTWGVFP 554
[28][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 179 bits (453), Expect = 2e-43
Identities = 89/201 (44%), Positives = 126/201 (62%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L
Sbjct: 360 FWASRPKSYIHRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGQEL 419
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F + G+ N PW++ D L PET ++ L+K+N +G LTINS
Sbjct: 420 SSEESVFEVFTYYISGEPNPNGHKVTCLPWND-DPLAPETNLLKSELQKVNKRGILTINS 478
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD-RPFLTYMAVNKE 510
QP VNG+ S P VGWG GYV+QKAYLEFF S E + AL++ K P + Y VN
Sbjct: 479 QPNVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEMVTALIKVLKRYEPRVNYHIVNVH 538
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N +AVTWG+FP
Sbjct: 539 GQNITNAADLQPSAVTWGIFP 559
[29][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 178 bits (451), Expect = 3e-43
Identities = 87/202 (43%), Positives = 124/202 (61%), Gaps = 11/202 (5%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FW++RPKSYI RT WD++P+GRWG+S PS+ L+D+ +++ + +++ ++ W L
Sbjct: 344 FWSSRPKSYIHRTSNWDEFPNGRWGNSSAPSFAELSDHHLFYLKSKESEEERLKMWGEKL 403
Query: 175 KSVEDIYERFRLFCLGKLRTNPWSEL--------DGLQPETKIINEHLEKINTKGFLTIN 330
+ED+Y F+ + GK N W D LQPET ++++ L +IN GFLT N
Sbjct: 404 DCIEDVYHVFQCYLSGK--KNKWGYKVKSLPLNDDELQPETSLLSDQLYRINGHGFLTTN 461
Query: 331 SQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKE 510
SQPAVN S GWGG GGY+YQKAYLEFF K+ +D L+E D P + Y ++
Sbjct: 462 SQPAVNAALSTDERFGWGGAGGYIYQKAYLEFFMHKKNVDFLLEVLNDNPRVNYHIIDSH 521
Query: 511 GVW-KSNVGQTDVNAVTWGVFP 573
G + K+N + AVTWGVFP
Sbjct: 522 GCYDKTNADRYSPIAVTWGVFP 543
[30][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 177 bits (450), Expect = 4e-43
Identities = 90/191 (47%), Positives = 123/191 (64%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR +SY++RT WD++P+GRWGDS +P++G L Y + + +++ I+ W PL S
Sbjct: 324 FWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDSYG-IGLKGTNEQNIKLWGTPL-S 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
++D+ + F + GKL + PWSE T I N+ ++ +N +GFLTINSQPAVNG KS
Sbjct: 382 IKDLSDLFVRYMEGKLESLPWSEQPITGEATSIRNDLID-LNRRGFLTINSQPAVNGAKS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
PT GWG GYVYQKAYLE S E + ++ + + P TY AVNK+G K+N
Sbjct: 441 SDPTFGWGPRNGYVYQKAYLEVLVSPEYIAEIITRIERDPEFTYYAVNKDGDLKTNAPNE 500
Query: 541 DVNAVTWGVFP 573
NAVTWGVFP
Sbjct: 501 GPNAVTWGVFP 511
[31][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 177 bits (449), Expect = 5e-43
Identities = 88/201 (43%), Positives = 129/201 (64%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L
Sbjct: 389 FWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEEL 448
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F L+ G+ N PW++ + L ET ++ E L ++N +G LTINS
Sbjct: 449 TSEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINS 507
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKE 510
QP +NG+ S P VGWG GGYV+QKAYLEFF S+E +AL++ K + Y VN +
Sbjct: 508 QPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVK 567
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N + NAVTWG+FP
Sbjct: 568 GENITNAPELQPNAVTWGIFP 588
[32][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform 4
n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 177 bits (449), Expect = 5e-43
Identities = 88/201 (43%), Positives = 129/201 (64%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L
Sbjct: 407 FWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEEL 466
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F L+ G+ N PW++ + L ET ++ E L ++N +G LTINS
Sbjct: 467 TSEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINS 525
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKE 510
QP +NG+ S P VGWG GGYV+QKAYLEFF S+E +AL++ K + Y VN +
Sbjct: 526 QPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVK 585
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N + NAVTWG+FP
Sbjct: 586 GENITNAPELQPNAVTWGIFP 606
[33][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 177 bits (449), Expect = 5e-43
Identities = 88/201 (43%), Positives = 129/201 (64%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L
Sbjct: 366 FWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEEL 425
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F L+ G+ N PW++ + L ET ++ E L ++N +G LTINS
Sbjct: 426 TSEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINS 484
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKE 510
QP +NG+ S P VGWG GGYV+QKAYLEFF S+E +AL++ K + Y VN +
Sbjct: 485 QPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVK 544
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N + NAVTWG+FP
Sbjct: 545 GENITNAPELQPNAVTWGIFP 565
[34][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 176 bits (447), Expect = 9e-43
Identities = 89/200 (44%), Positives = 122/200 (61%), Gaps = 10/200 (5%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKK--LIEEWAVPL 174
FW++RPKSYI RT WD +P+GRWG+S +P++G L DY ++K K L++ W L
Sbjct: 370 FWSSRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALLQMWGEEL 429
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F + + + PW++ + L PET ++ + LEK+N +G LTINS
Sbjct: 430 LSEESVFEVFTCYITAQTNRSGQKVLCLPWND-EPLAPETNLLKDELEKVNRRGVLTINS 488
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD-RPFLTYMAVNKE 510
QP +NG+ S P VGWG GGYVYQKAYLEFF S E + AL++ K P + Y VN
Sbjct: 489 QPNINGKPSTDPIVGWGPAGGYVYQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVH 548
Query: 511 GVWKSNVGQTDVNAVTWGVF 570
G +N NAVTWG+F
Sbjct: 549 GRNLTNAPDMQPNAVTWGIF 568
[35][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 176 bits (447), Expect = 9e-43
Identities = 89/200 (44%), Positives = 122/200 (61%), Gaps = 10/200 (5%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKK--LIEEWAVPL 174
FW++RPKSYI RT WD +P+GRWG+S +P++G L DY ++K K L++ W L
Sbjct: 370 FWSSRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALLQMWGEEL 429
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F + + + PW++ + L PET ++ + LEK+N +G LTINS
Sbjct: 430 LSEESVFEVFTCYITAQTNRSGQKVLCLPWND-EPLAPETNLLKDELEKVNRRGVLTINS 488
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD-RPFLTYMAVNKE 510
QP +NG+ S P VGWG GGYVYQKAYLEFF S E + AL++ K P + Y VN
Sbjct: 489 QPNINGKPSTDPIVGWGPAGGYVYQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVH 548
Query: 511 GVWKSNVGQTDVNAVTWGVF 570
G +N NAVTWG+F
Sbjct: 549 GRNLTNAPDMQPNAVTWGIF 568
[36][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 176 bits (446), Expect = 1e-42
Identities = 88/201 (43%), Positives = 128/201 (63%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ + L++ W L
Sbjct: 389 FWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEEL 448
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F L+ G+ N PW++ + L ET ++ E L ++N +G LTINS
Sbjct: 449 TSEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINS 507
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKE 510
QP +NG+ S P VGWG GGYV+QKAYLEFF S+E +AL++ K + Y VN +
Sbjct: 508 QPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVK 567
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N + NAVTWG+FP
Sbjct: 568 GENITNAPELQPNAVTWGIFP 588
[37][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 176 bits (446), Expect = 1e-42
Identities = 88/201 (43%), Positives = 128/201 (63%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ + L++ W L
Sbjct: 407 FWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEEL 466
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F L+ G+ N PW++ + L ET ++ E L ++N +G LTINS
Sbjct: 467 TSEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINS 525
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKE 510
QP +NG+ S P VGWG GGYV+QKAYLEFF S+E +AL++ K + Y VN +
Sbjct: 526 QPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVK 585
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N + NAVTWG+FP
Sbjct: 586 GENITNAPELQPNAVTWGIFP 606
[38][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 176 bits (446), Expect = 1e-42
Identities = 88/201 (43%), Positives = 128/201 (63%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ + L++ W L
Sbjct: 366 FWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEEL 425
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F L+ G+ N PW++ + L ET ++ E L ++N +G LTINS
Sbjct: 426 TSEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINS 484
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKE 510
QP +NG+ S P VGWG GGYV+QKAYLEFF S+E +AL++ K + Y VN +
Sbjct: 485 QPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVK 544
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N + NAVTWG+FP
Sbjct: 545 GENITNAPELQPNAVTWGIFP 565
[39][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 176 bits (445), Expect = 2e-42
Identities = 88/201 (43%), Positives = 125/201 (62%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSYI RT WD +P+GRWG+S +P++G L DY +++ ++ ++L++ W L
Sbjct: 368 FWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEEL 427
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
E ++E F + G+ N PW++ D L ET ++ + LEK+N +G LTINS
Sbjct: 428 TGEESVFEVFTCYITGEPNKNGYKVTCMPWND-DPLATETNLLKDQLEKVNRRGILTINS 486
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKE 510
QP +NG+ S P VGWG GGYV+QKAYLEFF S E + AL++ K + Y VN +
Sbjct: 487 QPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVQ 546
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N NAVTWG+FP
Sbjct: 547 GQNITNAPDLQPNAVTWGIFP 567
[40][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 175 bits (444), Expect = 2e-42
Identities = 95/192 (49%), Positives = 117/192 (60%), Gaps = 1/192 (0%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ-FMRPRAKDKKLIEEWAVPLK 177
FWANR KSYISRT WD+YP+GR+GDS +P+YG L Y +++ KD ++ W P
Sbjct: 325 FWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELDGYGVWIKQTVKDA--LKLWGHPT- 381
Query: 178 SVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEK 357
S DI F FC KL PWS+ Q ET +I E L +N GFLTINSQPAVN +
Sbjct: 382 SFADIASLFSRFCTKKLSALPWSDQAPSQ-ETSVIAEQLATMNEFGFLTINSQPAVNSAR 440
Query: 358 SDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQ 537
SD P GWG GYVYQKAYLEFF + L+ L+ + +TY +NK G ++N
Sbjct: 441 SDDPVFGWGPSNGYVYQKAYLEFFVNPTLLNLLLTHIERDSNITYYVINKRGDLRTNTHS 500
Query: 538 TDVNAVTWGVFP 573
NAVTWGVFP
Sbjct: 501 DGPNAVTWGVFP 512
[41][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 175 bits (443), Expect = 3e-42
Identities = 89/201 (44%), Positives = 125/201 (62%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKK--LIEEWAVPL 174
FWA+RPKSYI RT WD++P+GRWG+S +P++G L DY ++K + L++ W L
Sbjct: 360 FWASRPKSYIYRTQAWDEFPNGRWGNSSSPAFGELKDYYLFCLKSKTPRTELLKMWGEEL 419
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F + G+ N PW++ + L ET ++ E L K+N +G LTINS
Sbjct: 420 TSEESVFEVFTYYLSGEPNQNGYKVTCLPWND-EPLAAETSLMKEELLKVNQRGILTINS 478
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKE 510
QP +NG+ S P VGWG GGYV+QKAYLEFF S E ++AL++ K + Y VN +
Sbjct: 479 QPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSETVEALLQVLKKYELRVNYHIVNVK 538
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N + NAVTWG+FP
Sbjct: 539 GENITNAPELQPNAVTWGIFP 559
[42][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 175 bits (443), Expect = 3e-42
Identities = 87/201 (43%), Positives = 128/201 (63%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L
Sbjct: 396 FWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEEL 455
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S ++E F L+ G+ N PW++ + L ET ++ E L ++N +G LTINS
Sbjct: 456 TSEASVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINS 514
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKE 510
QP +NG+ S P VGWG GGYV+QKAYLEFF S+E +AL++ K + Y VN +
Sbjct: 515 QPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVK 574
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N + NAVTWG+FP
Sbjct: 575 GENITNAPELQPNAVTWGIFP 595
[43][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 175 bits (443), Expect = 3e-42
Identities = 92/191 (48%), Positives = 116/191 (60%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FWANR KSYISRT WD+YP+GR+GDS +P+YG + Y + K+ L + W P +
Sbjct: 285 FWANRTKSYISRTENWDEYPNGRFGDSRSPAYGEIDGYGTAIKQTKENAL-KLWGYPT-T 342
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+E++ F FC G+L PWS+ ET II L K+N GFLTINSQPAVNG +S
Sbjct: 343 LEEVSVLFAKFCKGELDALPWSD-SAPSKETSIIATQLAKMNELGFLTINSQPAVNGARS 401
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
D GWG GYVYQKAYLEFF L L++ + +TY +NK G ++N
Sbjct: 402 DDKIFGWGPSNGYVYQKAYLEFFVDPALLQLLLKHLERDTNITYHVINKRGDLQTNTHSE 461
Query: 541 DVNAVTWGVFP 573
NAVTWGVFP
Sbjct: 462 GPNAVTWGVFP 472
[44][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 174 bits (441), Expect = 4e-42
Identities = 86/201 (42%), Positives = 129/201 (64%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSYI RT GWD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L
Sbjct: 371 FWASRPKSYIYRTQGWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEEL 430
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F + G+ + PW++ + L ET ++ E L ++N G LTINS
Sbjct: 431 TSEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINS 489
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKE 510
QP +NG+ S P VGWG GGYV+QKAYLEFF S+E ++AL++ K + Y V+ +
Sbjct: 490 QPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVK 549
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N + NAVTWG+FP
Sbjct: 550 GENITNAPELQPNAVTWGIFP 570
[45][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 174 bits (441), Expect = 4e-42
Identities = 86/201 (42%), Positives = 129/201 (64%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSYI RT GWD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L
Sbjct: 406 FWASRPKSYIYRTQGWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEEL 465
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F + G+ + PW++ + L ET ++ E L ++N G LTINS
Sbjct: 466 TSEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINS 524
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKE 510
QP +NG+ S P VGWG GGYV+QKAYLEFF S+E ++AL++ K + Y V+ +
Sbjct: 525 QPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVK 584
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N + NAVTWG+FP
Sbjct: 585 GENITNAPELQPNAVTWGIFP 605
[46][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 174 bits (440), Expect = 6e-42
Identities = 87/191 (45%), Positives = 119/191 (62%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR +SY++RT WD++P+GRWGDS +P++G L Y + + +++ ++ W P+
Sbjct: 324 FWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDSYG-IGLKGTNEQNVKLWGSPM-C 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+ D+ + F + GKL + PWSE + E I L +N +GFLTINSQPAVNG KS
Sbjct: 382 IRDLSDLFVRYMEGKLDSLPWSE-QAITTEAGPIRSDLIDLNRRGFLTINSQPAVNGAKS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG GYVYQKAYLE F S E + ++ + + P TY AVNK+G K+N
Sbjct: 441 SDPVFGWGPRNGYVYQKAYLEVFVSPEYISEIITRLERDPEFTYYAVNKDGDLKTNAPNE 500
Query: 541 DVNAVTWGVFP 573
NAVTWGVFP
Sbjct: 501 GPNAVTWGVFP 511
[47][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 173 bits (439), Expect = 8e-42
Identities = 86/201 (42%), Positives = 128/201 (63%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L
Sbjct: 365 FWATRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEEL 424
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F + G+ N PW++ + L ET ++ E L ++N +G LTINS
Sbjct: 425 TSEESVFEVFAHYLSGEPNQNGYKVTCLPWND-EPLAAETSLMKEELLRVNRQGVLTINS 483
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKE 510
QP +NG+ S P VGWG GGYV+QKAYLEFF S+E ++AL++ K + Y V+ +
Sbjct: 484 QPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVK 543
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N + NAVTWG+FP
Sbjct: 544 GENITNAPELQPNAVTWGIFP 564
[48][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 173 bits (439), Expect = 8e-42
Identities = 87/201 (43%), Positives = 126/201 (62%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQF--MRPRAKDKKLIEEWAVPL 174
FWA+RPKSYI RT WD++P+GRWG+S +P++G L +Y ++ ++ ++L++ W L
Sbjct: 363 FWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKNYYLFCLKSKSPREELLKMWGQEL 422
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F + G+ N PW++ + L ET ++ E L+K+N +G LTINS
Sbjct: 423 TSEESVFEVFAYYLSGEPNQNGYKVTCLPWND-EPLAAETSLLKEELQKVNRRGILTINS 481
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKE 510
QP +NG+ S P VGWG GGYV+QKAYLEFF S E + AL++ K + Y VN +
Sbjct: 482 QPNINGKPSADPVVGWGPSGGYVFQKAYLEFFTSSETVAALLKVLKKYELRVNYHIVNVK 541
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N NAVTWG+FP
Sbjct: 542 GENITNAPDMQPNAVTWGIFP 562
[49][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 173 bits (438), Expect = 1e-41
Identities = 91/201 (45%), Positives = 120/201 (59%), Gaps = 11/201 (5%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FW +RPKSYI RT GWD++P+GRWGDS +P++G L DY F+R R KL W L
Sbjct: 339 FWCDRPKSYIHRTQGWDEFPNGRWGDSASPAFGELKDYHLFFLRSRTAKDKLRSLWGKEL 398
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S D+++ F+ F G + N PW++ DGL PET +++ L + N G LTINS
Sbjct: 399 TSEADVWKVFKHFITGAVNENGVKVTETPWND-DGLSPETNVLSSTLSRYNELGVLTINS 457
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDAL-VEKTKDRPFLTYMAVNKE 510
QP VN S P GWG GGY+ QKAYLEFF +K +AL K P + Y +NK
Sbjct: 458 QPNVNAVPSTHPIYGWGDKGGYISQKAYLEFFINKHYAEALKTVLPKYHPRVNYHMINKC 517
Query: 511 GVW-KSNVGQTDVNAVTWGVF 570
G +N +++ NAVTWG+F
Sbjct: 518 GTTDHTNADRSNPNAVTWGIF 538
[50][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 173 bits (438), Expect = 1e-41
Identities = 85/201 (42%), Positives = 129/201 (64%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L
Sbjct: 365 FWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEEL 424
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E +++ F + G+ N PW++ + L ET ++ E L ++N +G LTINS
Sbjct: 425 TSEESVFQVFAHYLSGEPNQNGYKVTCLPWND-EPLAAETSLMKEELLRVNRRGILTINS 483
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKE 510
QP +NG+ S P VGWG GGYV+QKAYLEFF S+E ++AL++ K + Y V+ +
Sbjct: 484 QPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVK 543
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N + NAVTWG+FP
Sbjct: 544 GENITNAPELQPNAVTWGIFP 564
[51][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
RepID=UPI0000E814FF
Length = 508
Score = 172 bits (437), Expect = 1e-41
Identities = 89/202 (44%), Positives = 122/202 (60%), Gaps = 11/202 (5%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKD---KKLIEEWAVP 171
FWA+RPKSYI RT WD +P+GRWG+S +P++G L DY ++K ++L++ W
Sbjct: 224 FWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKPSPREELLKMWGEE 283
Query: 172 LKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTIN 330
L E ++E F + G+ N PW++ D L ET ++ E LEK+N +G LTIN
Sbjct: 284 LTGEESVFEVFTCYITGEPNKNGHRVTCMPWND-DPLATETSLLKEQLEKVNRRGILTIN 342
Query: 331 SQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNK 507
SQP +NG+ S P GWG GGYV+QKAYLEFF S E + AL++ K + Y VN
Sbjct: 343 SQPNINGKPSTDPIFGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYELRVNYHIVNV 402
Query: 508 EGVWKSNVGQTDVNAVTWGVFP 573
+G +N NAVTWG+FP
Sbjct: 403 KGQNITNAPDLQPNAVTWGIFP 424
[52][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Canis lupus familiaris RepID=UPI00005A03BF
Length = 780
Score = 172 bits (435), Expect = 2e-41
Identities = 86/201 (42%), Positives = 128/201 (63%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L
Sbjct: 491 FWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEEL 550
Query: 175 KSVEDIYERFRLFCLG-------KLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F + G K+ PW++ + L ET ++ E L ++N +G LTINS
Sbjct: 551 TSEESVFEVFARYLSGEPNQHGYKVTCLPWND-EPLAAETSLMKEELLRVNRQGILTINS 609
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKE 510
QP +NG+ S P VGWG GGYV+QKAYLEFF S+E + AL++ K + Y V+ +
Sbjct: 610 QPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVK 669
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N + NAVTWG+FP
Sbjct: 670 GENITNAPELQPNAVTWGIFP 690
[53][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 172 bits (435), Expect = 2e-41
Identities = 86/201 (42%), Positives = 128/201 (63%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L
Sbjct: 407 FWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEEL 466
Query: 175 KSVEDIYERFRLFCLG-------KLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F + G K+ PW++ + L ET ++ E L ++N +G LTINS
Sbjct: 467 TSEESVFEVFARYLSGEPNQHGYKVTCLPWND-EPLAAETSLMKEELLRVNRQGILTINS 525
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKE 510
QP +NG+ S P VGWG GGYV+QKAYLEFF S+E + AL++ K + Y V+ +
Sbjct: 526 QPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVK 585
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N + NAVTWG+FP
Sbjct: 586 GENITNAPELQPNAVTWGIFP 606
[54][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 171 bits (434), Expect = 3e-41
Identities = 85/201 (42%), Positives = 128/201 (63%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L
Sbjct: 365 FWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEEL 424
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E +++ F G+ N PW++ + L ET ++ E L ++N +G LTINS
Sbjct: 425 TSEESVFQVFAHHLSGEPNQNGYKVTCLPWND-EPLAAETSLMKEELLRVNRRGILTINS 483
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKE 510
QP +NG+ S P VGWG GGYV+QKAYLEFF S+E ++AL++ K + Y V+ +
Sbjct: 484 QPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVK 543
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N + NAVTWG+FP
Sbjct: 544 GENITNAPELQPNAVTWGIFP 564
[55][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 171 bits (433), Expect = 4e-41
Identities = 88/191 (46%), Positives = 119/191 (62%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR KSY++RT WD++P+GRWGDS +P++G L Y + + +++ I+ W P KS
Sbjct: 324 FWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDAYG-IGLKGSNEQNIKLWGQP-KS 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
++DI E F + + + PWSE + E II L ++N +GFLTINSQPAV+G KS
Sbjct: 382 IKDIAELFVSYLENGIESLPWSEAP-ISSEADIIKSDLIELNRRGFLTINSQPAVDGVKS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG GYVYQKAYLE + + + LV + + P LTY AV K G ++N
Sbjct: 441 SDPVYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQHDPDLTYYAVKKTGDLQTNAQSD 500
Query: 541 DVNAVTWGVFP 573
NAVTWGVFP
Sbjct: 501 GPNAVTWGVFP 511
[56][TOP]
>UniRef100_UPI0000ECA34F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Gallus
gallus RepID=UPI0000ECA34F
Length = 640
Score = 170 bits (431), Expect = 6e-41
Identities = 88/202 (43%), Positives = 121/202 (59%), Gaps = 11/202 (5%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAK---DKKLIEEWAVP 171
FWA+RPKSYI RT WD +P+GRWG+S +P++G L DY ++ ++L++ W
Sbjct: 356 FWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSSLPPREELLKMWGEE 415
Query: 172 LKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTIN 330
L E ++E F + G+ N PW++ D L ET ++ E LEK+N +G LTIN
Sbjct: 416 LTGEESVFEVFTCYITGEPNKNGHRVTCMPWND-DPLATETSLLKEQLEKVNRRGILTIN 474
Query: 331 SQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNK 507
SQP +NG+ S P GWG GGYV+QKAYLEFF S E + AL++ K + Y VN
Sbjct: 475 SQPNINGKPSTDPIFGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYELRVNYHIVNV 534
Query: 508 EGVWKSNVGQTDVNAVTWGVFP 573
+G +N NAVTWG+FP
Sbjct: 535 KGQNITNAPDLQPNAVTWGIFP 556
[57][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 170 bits (430), Expect = 8e-41
Identities = 85/201 (42%), Positives = 125/201 (62%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSY+ RT WD++P+GRWG+S P++ +D+ ++R +AK +++++ W L
Sbjct: 311 FWASRPKSYLYRTSDWDEFPNGRWGNSSAPAFRDFSDHHLFYLRSKAKKEQMLKMWGQQL 370
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
V+D++E F+ + G+ N PW++ + L ET I E L N+ G L+INS
Sbjct: 371 NDVQDVFEVFKCYISGEKNENGVKVTSLPWND-EELALETSFIKEKLIHFNSNGILSINS 429
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNK-E 510
QP+VN S P +GWGG GGY+YQKAYLEFF S E + L+++ K+ P + Y VN +
Sbjct: 430 QPSVNAASSTDPLLGWGGEGGYIYQKAYLEFFASPEVVYILLQELKNYPQVNYHVVNNHD 489
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
V +N AVTWGVFP
Sbjct: 490 TVDITNCDSQTPVAVTWGVFP 510
[58][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 169 bits (429), Expect = 1e-40
Identities = 88/190 (46%), Positives = 117/190 (61%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR SYI+RT WD+YP+GRW D+ +P++G L Y +R + +++ I+ W P KS
Sbjct: 325 FWRNRNASYIARTADWDEYPNGRWTDARSPAFGELNAYG-VRLKGTNEQNIKLWGAP-KS 382
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
++D+ + F + GK+ PWS+ + PET I L +N +GFLTINSQPAVNG KS
Sbjct: 383 IKDLSDIFVRYLNGKVERLPWSD-SAVTPETSDIQNELLDLNKRGFLTINSQPAVNGVKS 441
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG GYVYQKAYLE E +D L+ + + P LTY VNK G K+
Sbjct: 442 TDPVHGWGPRNGYVYQKAYLELLVPPEHVDELLRRIEKNPDLTYYCVNKTGELKAR-SDE 500
Query: 541 DVNAVTWGVF 570
NAVTWG+F
Sbjct: 501 GPNAVTWGIF 510
[59][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 169 bits (428), Expect = 1e-40
Identities = 87/191 (45%), Positives = 116/191 (60%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR KSY+ RT WD++P+GRWGDS +P++G L Y + + ++W P K+
Sbjct: 324 FWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGSNEANR-KKWGEP-KA 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
++DI E F + K+ + PWSE L E I + L ++N +G LTINSQPAVNG KS
Sbjct: 382 IQDIAELFVSYLNNKIESLPWSE-SPLTTEADEIRDDLIELNKRGLLTINSQPAVNGVKS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG GYVYQK+YLE D ++ + ++ P LTY AV K+G +SNV
Sbjct: 441 SHPIHGWGPDNGYVYQKSYLELLVHPGVFDKMISRIENHPDLTYYAVTKDGELRSNVTSD 500
Query: 541 DVNAVTWGVFP 573
NAVTWGVFP
Sbjct: 501 GPNAVTWGVFP 511
[60][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 169 bits (428), Expect = 1e-40
Identities = 84/201 (41%), Positives = 127/201 (63%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L
Sbjct: 406 FWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEEL 465
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F + G+ + PW++ + L ET ++ E L ++N G LTINS
Sbjct: 466 TSEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINS 524
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKE 510
QP +N + S P VGWG GGYV+QKAYLEFF S+E ++AL++ K + Y V+ +
Sbjct: 525 QPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVK 584
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N + NAVTWG+FP
Sbjct: 585 GENITNAPELQPNAVTWGIFP 605
[61][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 169 bits (428), Expect = 1e-40
Identities = 84/201 (41%), Positives = 127/201 (63%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L
Sbjct: 406 FWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEEL 465
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F + G+ + PW++ + L ET ++ E L ++N G LTINS
Sbjct: 466 TSEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINS 524
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKE 510
QP +N + S P VGWG GGYV+QKAYLEFF S+E ++AL++ K + Y V+ +
Sbjct: 525 QPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVK 584
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N + NAVTWG+FP
Sbjct: 585 GENITNAPELQPNAVTWGIFP 605
[62][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 169 bits (428), Expect = 1e-40
Identities = 84/201 (41%), Positives = 127/201 (63%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L
Sbjct: 406 FWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEEL 465
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F + G+ + PW++ + L ET ++ E L ++N G LTINS
Sbjct: 466 TSEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINS 524
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKE 510
QP +N + S P VGWG GGYV+QKAYLEFF S+E ++AL++ K + Y V+ +
Sbjct: 525 QPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVK 584
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N + NAVTWG+FP
Sbjct: 585 GENITNAPELQPNAVTWGIFP 605
[63][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 169 bits (428), Expect = 1e-40
Identities = 84/201 (41%), Positives = 127/201 (63%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L
Sbjct: 365 FWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEEL 424
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F + G+ + PW++ + L ET ++ E L ++N G LTINS
Sbjct: 425 TSEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINS 483
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKE 510
QP +N + S P VGWG GGYV+QKAYLEFF S+E ++AL++ K + Y V+ +
Sbjct: 484 QPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVK 543
Query: 511 GVWKSNVGQTDVNAVTWGVFP 573
G +N + NAVTWG+FP
Sbjct: 544 GENITNAPELQPNAVTWGIFP 564
[64][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 168 bits (425), Expect = 3e-40
Identities = 86/190 (45%), Positives = 120/190 (63%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW +R +SY++RT WD++P+GRW DS +P++G L Y + + +++ I+ W P KS
Sbjct: 324 FWRHRHQSYVARTQSWDEFPNGRWTDSRSPAFGELDVYG-IGLKGTNEQNIKLWGEP-KS 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
V+D+ + F F GKL PWSE + E+ II + L +N +GFLTINSQPA+NG KS
Sbjct: 382 VKDLSDIFIRFLEGKLDRLPWSE-SAITQESDIIKDDLIALNNRGFLTINSQPAINGAKS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG GYVYQKAYLE S +D ++ + + P LTY +NK G ++N T
Sbjct: 441 SHPIYGWGPKNGYVYQKAYLELLISPTLIDEVIRRIETNPDLTYHCINKNGELRTNSSDT 500
Query: 541 DVNAVTWGVF 570
NAVTWG+F
Sbjct: 501 P-NAVTWGIF 509
[65][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 167 bits (423), Expect = 5e-40
Identities = 91/195 (46%), Positives = 117/195 (60%), Gaps = 5/195 (2%)
Frame = +1
Query: 4 WANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTD----YQFMRPRAKDKKLIEEWAVP 171
WANRPKSY+ RT WD++P+GRWGDS +P++G L++ Y F D++ + + P
Sbjct: 361 WANRPKSYVLRTEDWDEFPNGRWGDSTSPAFGELSNFSHYYSFSLGSEDDQRNMLG-SNP 419
Query: 172 LKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNG 351
KS ED+YE F L+ GK+ PW E LQPE+ +I L +N GFLTINSQP+VN
Sbjct: 420 TKS-EDVYEVFALYIEGKIPHIPWCEAT-LQPESFLIQTKLAALNRAGFLTINSQPSVNA 477
Query: 352 EKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEG-VWKSN 528
S + GWGGPGGY+YQKAY E FCS E + LV K + AVN G +
Sbjct: 478 ALSTHESFGWGGPGGYIYQKAYCECFCSPENMRCLVNMVKQNQSMNVYAVNNAGNCIQEG 537
Query: 529 VGQTDVNAVTWGVFP 573
V A+TWGVFP
Sbjct: 538 TELGGVTALTWGVFP 552
[66][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 165 bits (418), Expect = 2e-39
Identities = 84/191 (43%), Positives = 122/191 (63%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR +SY++RT WD++P+GRWGDS +P++G L Y + R +K++E W P K+
Sbjct: 324 FWKNRKQSYVARTQDWDEFPNGRWGDSRSPAFGELETYGVLL-RQSPQKVLELWGEP-KT 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
V+D+ + GKL + PWS++ + E + I + ++N +G LTINSQPAVNG KS
Sbjct: 382 VDDLKTLLVNYLNGKLASLPWSDVP-ISNEIETIKPQILELNNRGILTINSQPAVNGAKS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG GYVYQKAYLE + E + LV+K +++ +T+ AVNK G ++N
Sbjct: 441 THPVHGWGPKNGYVYQKAYLELLVTPEVAEKLVKKLENQSEITFYAVNKTGNLQTN-APG 499
Query: 541 DVNAVTWGVFP 573
NAVTWG++P
Sbjct: 500 GPNAVTWGIYP 510
[67][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 164 bits (416), Expect = 3e-39
Identities = 84/191 (43%), Positives = 111/191 (58%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW R +SY+SRT WD+ PHGRWGDS +P++G ++ R K++ W P KS
Sbjct: 327 FWRTRNESYVSRTDQWDELPHGRWGDSRSPAFGEFDAIRYGL-RMSPKEITTSWGSP-KS 384
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+I + F +C K+ + PWS+L + E +I + L +N FLTINSQPA+NGEKS
Sbjct: 385 YSEIGDLFARYCEKKISSLPWSDLP-ISDEADLIRDQLLSMNRNAFLTINSQPALNGEKS 443
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG P GYV+QK Y+EFF L+ L E K ++Y NK G +N
Sbjct: 444 SHPVFGWGPPNGYVFQKPYVEFFVHPSLLNELKETVKKLNSVSYFVTNKNGDLDTNSQYE 503
Query: 541 DVNAVTWGVFP 573
NAVTWGVFP
Sbjct: 504 IPNAVTWGVFP 514
[68][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 164 bits (415), Expect = 5e-39
Identities = 87/190 (45%), Positives = 117/190 (61%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR SY++RT WD+YP+GRW DS +P++G L Y + + +++ I+ W P KS
Sbjct: 324 FWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDAYG-VGLKGTNEQNIKLWGEP-KS 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
++DI + F F GKL PWS+ + E I E L K+N +GFLTINSQPAVNG KS
Sbjct: 382 IKDISDIFVNFLTGKLDRLPWSD-SPITTEAHEIQEDLLKLNQRGFLTINSQPAVNGVKS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG G+VYQKAYLE +D L+ + + LTY A NK+G K+N +
Sbjct: 441 SHPVYGWGPKNGFVYQKAYLELLVPSNLIDELITRIEKNDDLTYHATNKKGELKTNT-RD 499
Query: 541 DVNAVTWGVF 570
NA+TWG+F
Sbjct: 500 SPNALTWGIF 509
[69][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 163 bits (413), Expect = 8e-39
Identities = 87/207 (42%), Positives = 119/207 (57%), Gaps = 16/207 (7%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQF---------------MRPRA 135
FW NRP+SYI+RT WD++P+GRWGD +P++G L+DY
Sbjct: 324 FWQNRPRSYIARTGSWDEFPNGRWGDYRSPAFGDLSDYHLGGVTPPPGGSANNNTTTTTT 383
Query: 136 KDKKLIEE-WAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTK 312
D ++ + +S +D+Y F +C G ++ PW++ L E++ I E L +N
Sbjct: 384 GDSVVVPNIYGDSPQSEQDVYNVFASYCSGNIKRLPWND-SPLSLESENIKEQLVFLNKN 442
Query: 313 GFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTY 492
GFLTINSQPA+NG S GWGG G VY+KAY+EFF S E L+E K P +TY
Sbjct: 443 GFLTINSQPAINGLPSTDKQHGWGGKNGIVYKKAYIEFFASPENTLKLIEYFKKCPMITY 502
Query: 493 MAVNKEGVWKSNVGQTDVNAVTWGVFP 573
AVN++G K+N T NAVTWG+FP
Sbjct: 503 HAVNRKGDSKTNTKGT--NAVTWGIFP 527
[70][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 162 bits (411), Expect = 1e-38
Identities = 85/191 (44%), Positives = 113/191 (59%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR KSYI+RT WD++P+GRWGDS +P++G L Y + + ++W P ++
Sbjct: 324 FWRNRNKSYITRTQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGSNELNR-KKWGEP-QT 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
V+DI F + +L PWSE + E ++I + L +N +G +TINSQPAVNG KS
Sbjct: 382 VKDIANLFVRYLNQELEYLPWSEAP-ISSEAELIKDDLIALNNRGLITINSQPAVNGVKS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG GYVYQKAYLE S E + + +D P +TY AV K G +N
Sbjct: 441 THPVHGWGPANGYVYQKAYLELLVSPELFPEIKRRIEDHPDITYYAVTKSGNLHTNAPSE 500
Query: 541 DVNAVTWGVFP 573
NAVTWGVFP
Sbjct: 501 GPNAVTWGVFP 511
[71][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 162 bits (411), Expect = 1e-38
Identities = 84/190 (44%), Positives = 116/190 (61%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR SYI+RT WD+YP+GRW D+ +P++G L Y +R + +++ I+ W P KS
Sbjct: 325 FWRNRNASYIARTADWDEYPNGRWTDARSPAFGELNAYG-VRLKGTNEQNIKLWGAP-KS 382
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
++D+ + F + GKL PWS+ + ET I L +N +GFLTINSQPAVNG KS
Sbjct: 383 IKDLSDIFLRYLNGKLERLPWSD-SSVTLETSDIQNELLDLNKRGFLTINSQPAVNGVKS 441
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG G+VYQKAYLE E ++ L+ + + P LTY +NK G ++
Sbjct: 442 TDPVHGWGPRNGFVYQKAYLELLVPPEHVEELLRRIEKNPDLTYYCINKTGELRAR-SDE 500
Query: 541 DVNAVTWGVF 570
NAVTWG+F
Sbjct: 501 GPNAVTWGIF 510
[72][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 161 bits (408), Expect = 3e-38
Identities = 84/190 (44%), Positives = 116/190 (61%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW +R +SY++RT WD++P+GRW DS +P++G L Y + + +++ I+ W P KS
Sbjct: 324 FWRHRHQSYVARTQTWDEFPNGRWTDSRSPAFGELDVYG-IGLKGTNEQNIKLWGEP-KS 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
++D+ F F KL PWSE + ET II + L +N +GFLTINSQPA+NG S
Sbjct: 382 IKDLSSIFVRFLEAKLDRLPWSE-SSITEETDIIKQDLIDLNNRGFLTINSQPAINGASS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG GYVYQKAYLE E +D ++ + + LTY A NK G K+N +
Sbjct: 441 SHPVYGWGPKNGYVYQKAYLELLIPPEIIDEVITRIQKNADLTYYATNKNGELKTNTSDS 500
Query: 541 DVNAVTWGVF 570
NAVTWG+F
Sbjct: 501 P-NAVTWGIF 509
[73][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 161 bits (407), Expect = 4e-38
Identities = 80/178 (44%), Positives = 114/178 (64%), Gaps = 10/178 (5%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FWA+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L
Sbjct: 360 FWASRPKSYIHRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGQEL 419
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F + G+ N PW++ D L PET ++ L+K+N +G LTINS
Sbjct: 420 SSEESVFEVFTYYISGEPNPNGHKVTCLPWND-DPLAPETNLLKSELQKVNKRGILTINS 478
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD-RPFLTYMAVN 504
QP VNG+ S P VGWG GYV+QKAYLEFF S E + AL++ K P + Y VN
Sbjct: 479 QPNVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEMVTALIKVLKRYEPRVNYHIVN 536
[74][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 161 bits (407), Expect = 4e-38
Identities = 85/190 (44%), Positives = 118/190 (62%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW +R +SY++RT WD+YP+GRW DS +P++G L Y + + +++ I+ W P KS
Sbjct: 324 FWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYG-IGLKGTNEQNIKLWGEP-KS 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
++++ E F F G L PWSE + ET+II L +N KGFLTINSQPA++G S
Sbjct: 382 LKELSEIFIRFLNGSLDRLPWSE-GAVTEETEIIKSDLLDLNRKGFLTINSQPAIDGMPS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG GYVYQKAYLE S +D ++ + + LTY VNK+G K+N +
Sbjct: 441 SHPIYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNSDLTYYCVNKKGELKTNTTDS 500
Query: 541 DVNAVTWGVF 570
NAVTWG+F
Sbjct: 501 P-NAVTWGIF 509
[75][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 161 bits (407), Expect = 4e-38
Identities = 85/190 (44%), Positives = 118/190 (62%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW +R +SY++RT WD+YP+GRW DS +P++G L Y + + +++ I+ W P KS
Sbjct: 324 FWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYG-IGLKGTNEQNIKLWGEP-KS 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
++++ E F F G L PWSE + ET+II L +N KGFLTINSQPA++G S
Sbjct: 382 LKELSEIFIRFLNGSLDRLPWSE-GAVTEETEIIKSDLLDLNRKGFLTINSQPAIDGMPS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG GYVYQKAYLE S +D ++ + + LTY VNK+G K+N +
Sbjct: 441 SHPIYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNSDLTYYCVNKKGELKTNTTDS 500
Query: 541 DVNAVTWGVF 570
NAVTWG+F
Sbjct: 501 P-NAVTWGIF 509
[76][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 160 bits (406), Expect = 5e-38
Identities = 88/193 (45%), Positives = 112/193 (58%), Gaps = 2/193 (1%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQF--MRPRAKDKKLIEEWAVPL 174
FW NR KSY+ RT WD++P+GRWGDS +P++G L Y + +++K E
Sbjct: 319 FWRNRNKSYVMRTQDWDEFPNGRWGDSRSPAFGELDAYGIGLLGTNEQNRKKFGE----P 374
Query: 175 KSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGE 354
KSV+DI F + ++ T PWSE L E + I + L +N +G +TINSQPAVNG
Sbjct: 375 KSVKDIATLFVRYVQKEVDTLPWSE-SPLDAEAEQIRDDLIDLNLRGLITINSQPAVNGV 433
Query: 355 KSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVG 534
+S P GWG P GYVYQKAYLE + L E+ D P LTY AV K G +N
Sbjct: 434 RSTHPIHGWGPPNGYVYQKAYLELLVHPAIFEQLKERIHDHPDLTYYAVTKSGNLHTNAT 493
Query: 535 QTDVNAVTWGVFP 573
NAVTWGVFP
Sbjct: 494 YEGPNAVTWGVFP 506
[77][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 160 bits (406), Expect = 5e-38
Identities = 83/200 (41%), Positives = 117/200 (58%), Gaps = 9/200 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR SYI+RT WD++P+GRWGDS +P++G + R KK + W P ++
Sbjct: 328 FWQNRKYSYITRTATWDEFPNGRWGDSRSPAFGDIDLCASELLRQSPKKAYDLWGTP-QT 386
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
++D + + G+L++ PWS+ + +T ++ E+L +N KGFLT+NSQPA+N KS
Sbjct: 387 LKDFSDIIVSYLQGELKSLPWSD-GPIGEDTSVMVENLINLNHKGFLTMNSQPALNAVKS 445
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALV---------EKTKDRPFLTYMAVNKEG 513
GWG GYVYQK YLEFFC K+ L L+ E ++Y AV+K G
Sbjct: 446 SEKVYGWGPKNGYVYQKQYLEFFCPKDLLPKLLHTIDSYNKSEGDASSSIISYYAVDKNG 505
Query: 514 VWKSNVGQTDVNAVTWGVFP 573
+N D+NAVTWGVFP
Sbjct: 506 NLSTNCKDDDINAVTWGVFP 525
[78][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 160 bits (404), Expect = 9e-38
Identities = 82/200 (41%), Positives = 119/200 (59%), Gaps = 9/200 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW +R SYISRT WD++P+GRWGDS +P++G + R KK E W +P +S
Sbjct: 328 FWQHRKYSYISRTATWDEFPNGRWGDSRSPAFGDIDLCASELLRQSPKKAFELWGLP-QS 386
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+ D+ + G L++ PWS+ + +T++I + L +N GF T+NSQPA+N KS
Sbjct: 387 LADLSGIIINYLKGDLKSLPWSD-GPVGDDTRVIVDDLIYLNQHGFFTMNSQPALNAVKS 445
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD---------RPFLTYMAVNKEG 513
GWG GYVYQK YLEFFC K+ + L+++ ++ F++Y AV+K+G
Sbjct: 446 SEKVFGWGPKNGYVYQKQYLEFFCHKDVVSKLLDQVEEFNIKGAESSSAFISYYAVDKDG 505
Query: 514 VWKSNVGQTDVNAVTWGVFP 573
+N D+NAVTWGVFP
Sbjct: 506 NLSTNCKDDDINAVTWGVFP 525
[79][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 159 bits (403), Expect = 1e-37
Identities = 84/190 (44%), Positives = 116/190 (61%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW +R +SY++RT WD++P+GRW DS +P++G L Y + + +++ I+ W P KS
Sbjct: 324 FWRHRHQSYVARTQTWDEFPNGRWTDSRSPAFGELDVYG-IGLKGTNEQNIKLWGEP-KS 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
++D+ F F G L PWSE + ET I + L +N +GFLTINSQPAVNG S
Sbjct: 382 IKDLSAIFIRFLEGGLDRLPWSE-SPITEETDDIKQDLIDLNNRGFLTINSQPAVNGMSS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG GYVYQKAYLE E + ++ + + P LTY A+NK G K+N +
Sbjct: 441 SHPVYGWGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNPDLTYYAINKNGELKTNTSDS 500
Query: 541 DVNAVTWGVF 570
NAVTWG+F
Sbjct: 501 P-NAVTWGIF 509
[80][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 159 bits (403), Expect = 1e-37
Identities = 83/190 (43%), Positives = 118/190 (62%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW +R +SY++RT WD+YP+GRW DS +P++G L Y + + +++ I+ W P KS
Sbjct: 324 FWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYG-IGLKGTNEQNIQLWGKP-KS 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
++++ E F F GKL PWSE + ET II L +N++GFLTINSQPA++G S
Sbjct: 382 LKELSEIFIRFLNGKLDRLPWSE-GAVTEETDIIKRDLLDLNSRGFLTINSQPAIDGVHS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG GYVYQKAYLE S ++ ++ + + LTY VNK G ++N +
Sbjct: 441 SHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVNKTGELRTNTSDS 500
Query: 541 DVNAVTWGVF 570
NAVTWG+F
Sbjct: 501 P-NAVTWGIF 509
[81][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 159 bits (402), Expect = 1e-37
Identities = 87/202 (43%), Positives = 118/202 (58%), Gaps = 11/202 (5%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVP--L 174
FW NR SYISRT WD++P+GRWGDS +P++G + + R KK + W P L
Sbjct: 328 FWQNRKYSYISRTSTWDEFPNGRWGDSRSPAFGDIDLFATDLLRQSPKKAFDLWGHPGTL 387
Query: 175 KSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGE 354
K DI F GKL + PWS+ + +++II ++L +N KGF T+NSQP++N
Sbjct: 388 KQFSDIIISF---LSGKLNSLPWSD-SAIGQDSEIIVDNLIALNKKGFFTLNSQPSLNAI 443
Query: 355 KSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEK---------TKDRPFLTYMAVNK 507
KS+ GWG GYVYQK YLEFF K+ + AL+ + + LTY AV++
Sbjct: 444 KSNDKVYGWGPKNGYVYQKQYLEFFVHKDIIPALLHQIDNYNRGQGDSNSSVLTYYAVDQ 503
Query: 508 EGVWKSNVGQTDVNAVTWGVFP 573
+G SN D+NAVTWGVFP
Sbjct: 504 KGKLFSNTKDDDINAVTWGVFP 525
[82][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 159 bits (402), Expect = 1e-37
Identities = 83/190 (43%), Positives = 118/190 (62%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW +R +SY++RT WD+YP+GRW DS +P++G L Y + + +++ I+ W P KS
Sbjct: 324 FWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYG-IGLKGTNEQNIQLWGKP-KS 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
++++ E F F GKL PWSE + ET II L +N++GFLTINSQPA++G S
Sbjct: 382 LKELSEIFIHFLNGKLDRLPWSE-GAVTEETDIIKRDLLDLNSRGFLTINSQPAIDGVHS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG GYVYQKAYLE S ++ ++ + + LTY VNK G ++N +
Sbjct: 441 SHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVNKTGELRTNTSDS 500
Query: 541 DVNAVTWGVF 570
NAVTWG+F
Sbjct: 501 P-NAVTWGIF 509
[83][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 159 bits (402), Expect = 1e-37
Identities = 87/202 (43%), Positives = 118/202 (58%), Gaps = 11/202 (5%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVP--L 174
FW NR SYISRT WD++P+GRWGDS +P++G + + R KK + W P L
Sbjct: 328 FWQNRKYSYISRTSTWDEFPNGRWGDSRSPAFGDIDLFATDLLRQSPKKAFDLWGHPGTL 387
Query: 175 KSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGE 354
K DI F GKL + PWS+ + +++II ++L +N KGF T+NSQP++N
Sbjct: 388 KQFSDIIISF---LSGKLNSLPWSD-SAIGQDSEIIVDNLIALNKKGFFTLNSQPSLNAI 443
Query: 355 KSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEK---------TKDRPFLTYMAVNK 507
KS+ GWG GYVYQK YLEFF K+ + AL+ + + LTY AV++
Sbjct: 444 KSNDKVYGWGPKNGYVYQKQYLEFFVHKDIIPALLHQIDNYNRGQGDSNSSVLTYYAVDQ 503
Query: 508 EGVWKSNVGQTDVNAVTWGVFP 573
+G SN D+NAVTWGVFP
Sbjct: 504 KGKLFSNTKDDDINAVTWGVFP 525
[84][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 159 bits (402), Expect = 1e-37
Identities = 81/191 (42%), Positives = 113/191 (59%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR KSY++RT WD++P+GRWGDS +P++G L Y ++ ++W P
Sbjct: 324 FWRNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGTNEQNR-QKWGEPT-C 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+ DI F + ++ PWSE + E +I ++L +N +G +T+NSQPAVNG KS
Sbjct: 382 IRDIANLFVRYLKKEIEYLPWSEAP-VAEEADLIKDYLLDLNKRGLITVNSQPAVNGVKS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG GYVYQKAYLE S E + ++ ++ P LTY AV K G+ ++N
Sbjct: 441 THPVHGWGPSKGYVYQKAYLELLVSPEVYPEIKKRIENHPDLTYHAVTKSGMLETNAPSD 500
Query: 541 DVNAVTWGVFP 573
NAVTWGVFP
Sbjct: 501 APNAVTWGVFP 511
[85][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 159 bits (401), Expect = 2e-37
Identities = 82/200 (41%), Positives = 118/200 (59%), Gaps = 9/200 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW +R SYISRT WD++P+GRWGDS +P++G + R KK E W +P +S
Sbjct: 328 FWQHRKYSYISRTATWDEFPNGRWGDSRSPAFGDIDLCASELLRQSPKKAFELWGLP-QS 386
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+ ++ + G L++ PWS+ + +TK+I + L +N GF T+NSQPA+N KS
Sbjct: 387 LAELSGIIINYLKGDLKSLPWSD-GPVGDDTKVIVDDLIYLNQHGFFTMNSQPALNAVKS 445
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD---------RPFLTYMAVNKEG 513
GWG GYVYQK YLEFFC K+ + L++ ++ F++Y AV+K+G
Sbjct: 446 SEKVFGWGPKNGYVYQKQYLEFFCHKDVVSKLLDHVEEFNVKGAESSSAFISYYAVDKDG 505
Query: 514 VWKSNVGQTDVNAVTWGVFP 573
+N D+NAVTWGVFP
Sbjct: 506 NLSTNCKDDDINAVTWGVFP 525
[86][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 159 bits (401), Expect = 2e-37
Identities = 84/190 (44%), Positives = 115/190 (60%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW +R +SY++RT WD++P+GRW DS +P++G L Y + + +++ I+ W P KS
Sbjct: 324 FWRHRHQSYVARTQTWDEFPNGRWTDSRSPAFGELDVYG-IGLKGTNEQNIKLWGEP-KS 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
++D+ F F G L PWSE + ET I L +N +GFLTINSQPAVNG S
Sbjct: 382 IKDLSAIFIRFLEGGLDRLPWSE-SPITEETDDIKHDLIDLNNRGFLTINSQPAVNGMSS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG GYVYQKAYLE E + ++ + + P LTY A+NK G K+N +
Sbjct: 441 SHPVYGWGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNPDLTYYAINKNGELKTNTSDS 500
Query: 541 DVNAVTWGVF 570
NAVTWG+F
Sbjct: 501 P-NAVTWGIF 509
[87][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 159 bits (401), Expect = 2e-37
Identities = 83/190 (43%), Positives = 118/190 (62%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW +R +SY++RT WD+YP+GRW DS +P++G L Y + + +++ I+ W P KS
Sbjct: 324 FWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYG-IGLKGTNEQNIQLWGKP-KS 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
++++ E F F GKL PWSE + ET II L +N++GFLTINSQPA++G S
Sbjct: 382 LKELSEIFIRFLNGKLDRLPWSE-GAVTEETDIIKRDLLDLNSRGFLTINSQPAIDGVHS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG GYVYQKAYLE S ++ ++ + + LTY VNK G ++N +
Sbjct: 441 SHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVNKTGELRTNTTDS 500
Query: 541 DVNAVTWGVF 570
NAVTWG+F
Sbjct: 501 P-NAVTWGIF 509
[88][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 159 bits (401), Expect = 2e-37
Identities = 82/190 (43%), Positives = 118/190 (62%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW +R +SY++RT WD+YP+GRW DS +P++G L Y + + +++ I+ W P KS
Sbjct: 324 FWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYG-VGLKGTNEQNIKLWGEP-KS 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
++++ E F F G L PWSE + ET ++ L +N +GFLTINSQPA++G S
Sbjct: 382 LKELSEIFVRFLNGNLDRLPWSE-GAVTEETDVLKLDLLDLNRRGFLTINSQPAIDGMPS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG GYVYQKAYLE S +D ++ + + P LTY VNK+G ++N +
Sbjct: 441 SHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKKGELRTNTTDS 500
Query: 541 DVNAVTWGVF 570
NAVTWG+F
Sbjct: 501 P-NAVTWGIF 509
[89][TOP]
>UniRef100_UPI000151BABB hypothetical protein PGUG_04648 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151BABB
Length = 355
Score = 158 bits (400), Expect = 3e-37
Identities = 83/199 (41%), Positives = 119/199 (59%), Gaps = 8/199 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR SYISRT WD++P+GRWGDS +P++G + + R K+ + W P +S
Sbjct: 68 FWQNRKYSYISRTSTWDEFPNGRWGDSRSPAFGDIDLFAADLLRQSPKRAFDLWGCP-QS 126
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+D+ + L++ PWS+ + +T II + L +N +GFLT+NSQP++N KS
Sbjct: 127 FKDLSNLVVSYLKNDLKSLPWSD-GPIGEDTAIIVDKLISLNQRGFLTMNSQPSLNCVKS 185
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKE---KLDALVEKTKDR-----PFLTYMAVNKEGV 516
+ GWG GYV+QK YLEFFC ++ KL +EK ++ FLTY A +K G
Sbjct: 186 NDKVYGWGPKNGYVFQKQYLEFFCHRDIFPKLLESIEKFNEKGGESCSFLTYYAADKNGE 245
Query: 517 WKSNVGQTDVNAVTWGVFP 573
+N + D+NAVTWGVFP
Sbjct: 246 LNTNTKEDDINAVTWGVFP 264
[90][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 158 bits (400), Expect = 3e-37
Identities = 83/190 (43%), Positives = 116/190 (61%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR SYI+RT WD++P+GRW DS +P++G L Y + + +++ I+ W P KS
Sbjct: 324 FWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDSYG-IGLKGTNEQNIQLWGEP-KS 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
++D+ F + GKL PWS+ + E K I +L ++N +G LTINSQPAVNG KS
Sbjct: 382 IKDLSRLFVRYLEGKLSRLPWSDTP-ISSEAKAIKPNLIELNNRGILTINSQPAVNGAKS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG G+VYQKAYLE LD L+ + + LTY AV+K G ++N +
Sbjct: 441 SHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIEGNEDLTYHAVSKNGELRTNTHDS 500
Query: 541 DVNAVTWGVF 570
NA+TWG+F
Sbjct: 501 P-NALTWGIF 509
[91][TOP]
>UniRef100_A5DMZ7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DMZ7_PICGU
Length = 355
Score = 158 bits (400), Expect = 3e-37
Identities = 83/199 (41%), Positives = 119/199 (59%), Gaps = 8/199 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR SYISRT WD++P+GRWGDS +P++G + + R K+ + W P +S
Sbjct: 68 FWQNRKYSYISRTSTWDEFPNGRWGDSRSPAFGDIDLFAADLLRQSPKRAFDLWGCP-QS 126
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+D+ + L++ PWS+ + +T II + L +N +GFLT+NSQP++N KS
Sbjct: 127 FKDLSNLVVSYLKNDLKSLPWSD-GPIGEDTAIIVDKLISLNQRGFLTMNSQPSLNCVKS 185
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKE---KLDALVEKTKDR-----PFLTYMAVNKEGV 516
+ GWG GYV+QK YLEFFC ++ KL +EK ++ FLTY A +K G
Sbjct: 186 NDKVYGWGPKNGYVFQKQYLEFFCHRDIFPKLLESIEKFNEKGGESCSFLTYYAADKNGE 245
Query: 517 WKSNVGQTDVNAVTWGVFP 573
+N + D+NAVTWGVFP
Sbjct: 246 LNTNTKEDDINAVTWGVFP 264
[92][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 158 bits (400), Expect = 3e-37
Identities = 84/190 (44%), Positives = 117/190 (61%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR SYI+RT WD++P+GRW DS +P++G L Y + + +++ I+ W P KS
Sbjct: 324 FWRNRNSSYIARTQIWDEFPNGRWTDSRSPAFGELDAYG-IGLKGTNEQNIKLWGEP-KS 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+ DI + F + GKL PWS+ + E I E+L ++N +G LT+NSQPAVNG +S
Sbjct: 382 IRDISQIFVRYVEGKLERLPWSD-SPISAEANAIKENLIELNGRGLLTVNSQPAVNGVRS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG G+VYQKAYLE F LD L+ + + LTY AV KEG ++N +
Sbjct: 441 SHPVYGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNDDLTYHAVAKEGELRTNT-RD 499
Query: 541 DVNAVTWGVF 570
NA+TWG+F
Sbjct: 500 SPNALTWGIF 509
[93][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 158 bits (399), Expect = 3e-37
Identities = 81/191 (42%), Positives = 114/191 (59%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR KSY+ RT WD++P+GRWGDS +P++G L Y + ++W P K+
Sbjct: 324 FWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGTNEANR-KKWGEP-KT 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
V+DI + F + ++ + PWSE L E I + L ++N +G LT+NSQPAVNG KS
Sbjct: 382 VQDIAQLFVRYLRNEIDSLPWSE-SPLTSEADEIRDDLVELNKRGLLTVNSQPAVNGVKS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
GWG GYVYQK+YLE + + ++ + ++ P LT+ AV K+G +SN
Sbjct: 441 SHAVHGWGPSNGYVYQKSYLELLVHPDVFNDMIGRIENHPDLTFYAVTKDGELRSNAPSD 500
Query: 541 DVNAVTWGVFP 573
NAVTWGVFP
Sbjct: 501 CPNAVTWGVFP 511
[94][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 158 bits (399), Expect = 3e-37
Identities = 83/190 (43%), Positives = 117/190 (61%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW +R +SY++RT WD+YP+GRW DS +P++G L Y + + +++ I+ W P KS
Sbjct: 310 FWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYG-IGLKGTNEQNIKLWGEP-KS 367
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
++++ E F F G L PWSE + ET +I L +N +GFLTINSQPA++G S
Sbjct: 368 LKELSEIFVRFLNGNLDRLPWSE-GAVTEETDVIKLDLLDLNRRGFLTINSQPAIDGMPS 426
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG GYVYQKAYLE S +D ++ + + P LTY VNK G ++N +
Sbjct: 427 SHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKIGELRTNTTDS 486
Query: 541 DVNAVTWGVF 570
NAVTWG+F
Sbjct: 487 P-NAVTWGIF 495
[95][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 157 bits (398), Expect = 4e-37
Identities = 82/191 (42%), Positives = 112/191 (58%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR KSY++RT WD++P+GRWGDS +P++G L Y + ++ ++W P S
Sbjct: 324 FWRNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDAYGVGLTGSNEQNR-KKWGEPT-S 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
++DI F + ++ PWSE + E +I + L ++N +G +T+NSQPAVNG KS
Sbjct: 382 IKDIANLFVRYLNKEIEYLPWSEAP-VAEEADLIKDDLIELNNRGLITVNSQPAVNGVKS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG GYVYQKAYLE S E + + + P LTY AV K G +N
Sbjct: 441 THPIHGWGPANGYVYQKAYLEMLISPELFPQIKSRIESHPDLTYHAVTKSGNLHTNAQFE 500
Query: 541 DVNAVTWGVFP 573
NAVTWGVFP
Sbjct: 501 GPNAVTWGVFP 511
[96][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6H337_AJECH
Length = 524
Score = 157 bits (397), Expect = 6e-37
Identities = 82/190 (43%), Positives = 117/190 (61%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW +R +SY++RT WD+YP+GRW DS +P++G L Y + + +++ I+ W P KS
Sbjct: 215 FWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYG-IGLKGTNEQNIKLWGEP-KS 272
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
++++ E F F G L PWSE + ET ++ L +N +GFLTINSQPA++G S
Sbjct: 273 LKELSEIFVRFLNGNLDRLPWSE-GAVTEETDVLKLDLLDLNRRGFLTINSQPAIDGMPS 331
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG GYVYQKAYLE S +D ++ + + P LTY VNK G ++N +
Sbjct: 332 SHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKIGELRTNTTDS 391
Query: 541 DVNAVTWGVF 570
NAVTWG+F
Sbjct: 392 P-NAVTWGIF 400
[97][TOP]
>UniRef100_Q8MQE7 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis elegans
RepID=Q8MQE7_CAEEL
Length = 642
Score = 156 bits (395), Expect = 1e-36
Identities = 88/206 (42%), Positives = 124/206 (60%), Gaps = 15/206 (7%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMR---PRAKDKKLIEEWAVP 171
+W+ RP+SYI+RT WDQ+P+GRWG+S +P++G ++ Y R D +L +
Sbjct: 359 YWSFRPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLSNLTTVRNADDRLAM-FGAN 417
Query: 172 LKSVEDIYERFRLFCLG-------KLRTNPWSELD-GLQPETKIINEHLEKINTKGFLTI 327
++S ED+ F + K+ PW+E + G+QPET +I+E L N G LT+
Sbjct: 418 IESFEDVKRVFINYITQAPNADGVKVTVLPWTEAETGVQPETSLISEQLVWCNENGILTV 477
Query: 328 NSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF---LTYMA 498
NSQP+VNG S P VGWG PGGY YQKAYLE F + E D L++ +R F + Y A
Sbjct: 478 NSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSDKLIQ-IIEREFPVRVNYHA 536
Query: 499 VNKEGVW-KSNVGQTDVNAVTWGVFP 573
+NK+ + K+N +T AVTWGVFP
Sbjct: 537 INKDSTFDKTNSEETTPIAVTWGVFP 562
[98][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S5W8_NEMVE
Length = 619
Score = 156 bits (395), Expect = 1e-36
Identities = 85/201 (42%), Positives = 113/201 (56%), Gaps = 10/201 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRA--KDKKLIEEWAVPL 174
FWA+RP+SY+ RT W+ P+GRWG+S + S+G L DY KD +L+ W L
Sbjct: 340 FWASRPRSYLIRTSNWEDMPNGRWGNSSSASFGDLKDYHLFLTGTSRKDSELLSMWGREL 399
Query: 175 KSVEDIYERFRLFCLG-------KLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S +D+++ F + G K+ PWS+ + L PET + E L N G LTINS
Sbjct: 400 NSEQDVFDIFVCYLTGRDNKQGFKVTELPWSDGE-LAPETIPLVEKLVHANQNGILTINS 458
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEG 513
QP++N S+ P GWG PGGYV+QKAYLEFF +E L + KD + + VN G
Sbjct: 459 QPSLNAVPSEDPNHGWGKPGGYVFQKAYLEFFAREEIALELYHQLKDGTRINFHLVNSSG 518
Query: 514 VWK-SNVGQTDVNAVTWGVFP 573
+N NAVTWGVFP
Sbjct: 519 ESDFTNANMYSPNAVTWGVFP 539
[99][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 156 bits (395), Expect = 1e-36
Identities = 82/190 (43%), Positives = 117/190 (61%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR SYI+RT WD++P+GRW DS +P++G L Y + + +++ I+ W P KS
Sbjct: 324 FWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDAYG-IGLKGTNEQNIKLWGEP-KS 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+ DI + F + GKL PWS+ + E I ++L ++N++G LT+NSQPAVNG +S
Sbjct: 382 IRDITQIFVRYLEGKLDRLPWSD-SPISGEANAIKDNLVQLNSRGLLTVNSQPAVNGVRS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG G+VYQKAYLE F LD L+ + + P LTY AV K ++N +
Sbjct: 441 SHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLTYHAVAKNRELRTNT-RD 499
Query: 541 DVNAVTWGVF 570
NA+TWG+F
Sbjct: 500 SPNALTWGIF 509
[100][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 156 bits (395), Expect = 1e-36
Identities = 82/190 (43%), Positives = 117/190 (61%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR SYI+RT WD++P+GRW DS +P++G L Y + + +++ I+ W P KS
Sbjct: 324 FWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDAYG-IGLKGTNEQNIKLWGEP-KS 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+ DI + F + GKL PWS+ + E I ++L ++N++G LT+NSQPAVNG +S
Sbjct: 382 IRDITQIFVRYLEGKLDRLPWSD-SPISGEANAIKDNLVQLNSRGLLTVNSQPAVNGVRS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG G+VYQKAYLE F LD L+ + + P LTY AV K ++N +
Sbjct: 441 SHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLTYHAVAKNRELRTNT-RD 499
Query: 541 DVNAVTWGVF 570
NA+TWG+F
Sbjct: 500 SPNALTWGIF 509
[101][TOP]
>UniRef100_Q17693 Probable methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis
elegans RepID=MTHR_CAEEL
Length = 663
Score = 156 bits (395), Expect = 1e-36
Identities = 88/206 (42%), Positives = 124/206 (60%), Gaps = 15/206 (7%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMR---PRAKDKKLIEEWAVP 171
+W+ RP+SYI+RT WDQ+P+GRWG+S +P++G ++ Y R D +L +
Sbjct: 380 YWSFRPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLSNLTTVRNADDRLAM-FGAN 438
Query: 172 LKSVEDIYERFRLFCLG-------KLRTNPWSELD-GLQPETKIINEHLEKINTKGFLTI 327
++S ED+ F + K+ PW+E + G+QPET +I+E L N G LT+
Sbjct: 439 IESFEDVKRVFINYITQAPNADGVKVTVLPWTEAETGVQPETSLISEQLVWCNENGILTV 498
Query: 328 NSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF---LTYMA 498
NSQP+VNG S P VGWG PGGY YQKAYLE F + E D L++ +R F + Y A
Sbjct: 499 NSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSDKLIQ-IIEREFPVRVNYHA 557
Query: 499 VNKEGVW-KSNVGQTDVNAVTWGVFP 573
+NK+ + K+N +T AVTWGVFP
Sbjct: 558 INKDSTFDKTNSEETTPIAVTWGVFP 583
[102][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 156 bits (394), Expect = 1e-36
Identities = 83/202 (41%), Positives = 116/202 (57%), Gaps = 11/202 (5%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVP--L 174
FW NR SY+SRT WD++P+GRWGDS +P++G + R K+ E W P L
Sbjct: 329 FWQNRKYSYVSRTATWDEFPNGRWGDSRSPAFGDIDLCASELLRQSPKRAYELWGTPGSL 388
Query: 175 KSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGE 354
K + DI + G L++ PWS+ + +TK+I + L ++N +G LT+NSQPA+N
Sbjct: 389 KELSDIVISY---LKGDLKSLPWSD-GSVGDDTKVIVDDLVELNKRGLLTMNSQPALNSI 444
Query: 355 KSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD---------RPFLTYMAVNK 507
KS GWG GYVYQK YLEFFC K+ + L++ D ++Y AV+
Sbjct: 445 KSSEKIFGWGPKNGYVYQKQYLEFFCHKDIIVKLLQTIDDYNNNQGDASSAIISYYAVDL 504
Query: 508 EGVWKSNVGQTDVNAVTWGVFP 573
+G +N D+NAVTWGVFP
Sbjct: 505 KGNLTTNCNDDDINAVTWGVFP 526
[103][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 156 bits (394), Expect = 1e-36
Identities = 81/190 (42%), Positives = 117/190 (61%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR SYI+RT WD++P+GRW DS +P++G L Y + + +++ I+ W P KS
Sbjct: 324 FWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDAYG-IGLKGTNEQNIKLWGEP-KS 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+ D+ + F + GKL PWS+ + E I ++L ++N++G LT+NSQPAVNG +S
Sbjct: 382 IRDVTQIFVRYLEGKLDRLPWSD-SPISGEANAIKDNLVQLNSRGLLTVNSQPAVNGVRS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG G+VYQKAYLE F LD L+ + + P LTY AV K ++N +
Sbjct: 441 SHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLTYHAVAKNRELRTNT-RD 499
Query: 541 DVNAVTWGVF 570
NA+TWG+F
Sbjct: 500 SPNALTWGIF 509
[104][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 155 bits (393), Expect = 2e-36
Identities = 83/190 (43%), Positives = 115/190 (60%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR SYI+RT WD++P+GRW DS +P++G L Y + + +++ I+ W P S
Sbjct: 324 FWRNRNSSYIARTAIWDEFPNGRWTDSRSPAFGELELYG-VGLKGTNEQNIKLWGEP-NS 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+ D+ E F F G L PWS+ + PET I + L ++N +GF TINSQPAVNG KS
Sbjct: 382 LRDLAEVFVRFLEGNLDRLPWSD-SPITPETSAIKDALVELNRRGFFTINSQPAVNGVKS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG G+VYQKAYLE +D L+ + + LTY AV K+G ++N +
Sbjct: 441 SHPVFGWGPKNGFVYQKAYLELLVPPYVIDELIARIEANEDLTYHAVTKKGELRTNT-RD 499
Query: 541 DVNAVTWGVF 570
NA+TWG+F
Sbjct: 500 SPNALTWGIF 509
[105][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 154 bits (389), Expect = 5e-36
Identities = 85/195 (43%), Positives = 112/195 (57%), Gaps = 5/195 (2%)
Frame = +1
Query: 4 WANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ----FMRPRAKDKKLIEEWAVP 171
W+NRPKSY+ RT WD++P+GRWGDS +P++G L+D F +D++ +
Sbjct: 322 WSNRPKSYVMRTDDWDEFPNGRWGDSTSPAFGELSDLSHFCSFTLGSDEDRRAMLGHNPQ 381
Query: 172 LKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNG 351
+S D+YE F + G + PW E LQPE+ +I L K+N GFLT+NSQP V+G
Sbjct: 382 AES--DVYEVFARYVEGSVPHIPWCETP-LQPESFLIQPQLAKLNRYGFLTVNSQPPVDG 438
Query: 352 EKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEG-VWKSN 528
S GWGG GG VYQKAY E F S K + L + D P L AVN G +
Sbjct: 439 LPSCHKVFGWGGKGGRVYQKAYFECFVSPSKANRLTQMVTDHPSLNMYAVNNAGQELRVG 498
Query: 529 VGQTDVNAVTWGVFP 573
V + V A+TWGVFP
Sbjct: 499 VEEGGVTALTWGVFP 513
[106][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 152 bits (385), Expect = 1e-35
Identities = 80/200 (40%), Positives = 116/200 (58%), Gaps = 9/200 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR SY++RT WD++P+GRWGDS +P++G + R K+ E W +P ++
Sbjct: 328 FWQNRKYSYVTRTATWDEFPNGRWGDSRSPAFGDIDLCASELLRQSPKRAQELWGLP-QT 386
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+ DI + G+L + PW + + +T II +HL ++N +T+NSQP++N +S
Sbjct: 387 ISDITGLVISYLKGQLNSLPWFD-GAIGEDTNIILDHLIELNENSLITLNSQPSLNSVRS 445
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKE----KLDALVEKTKDR-----PFLTYMAVNKEG 513
GWG GYVYQK YLEFFC K+ LD + + K++ ++Y AVNK G
Sbjct: 446 SDKVFGWGPKNGYVYQKQYLEFFCHKDVVARLLDHIDQYNKNQGDSTSAVISYYAVNKNG 505
Query: 514 VWKSNVGQTDVNAVTWGVFP 573
SN D+NAVTWGVFP
Sbjct: 506 NLISNCQDDDINAVTWGVFP 525
[107][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 152 bits (384), Expect = 2e-35
Identities = 83/190 (43%), Positives = 111/190 (58%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR SYI+RT WD++P+GRW DS +P++G L Y + + +++ I+ W P KS
Sbjct: 324 FWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDSYG-IGLKGTNEQNIKLWGEP-KS 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+ D+ F F GKL PWS+ + E I L +N KG TINSQPAVNG KS
Sbjct: 382 LRDLTHIFVNFLEGKLARLPWSDTP-ITTEANAIKTSLIDLNQKGLFTINSQPAVNGVKS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG GYVYQKAYLE +D L+ + + LTY AV+K G ++N +
Sbjct: 441 SHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNGDLTYHAVSKTGELRTNT-RD 499
Query: 541 DVNAVTWGVF 570
NA+TWG+F
Sbjct: 500 SPNALTWGIF 509
[108][TOP]
>UniRef100_UPI0000123E6B Hypothetical protein CBG12960 n=1 Tax=Caenorhabditis briggsae AF16
RepID=UPI0000123E6B
Length = 662
Score = 152 bits (383), Expect = 2e-35
Identities = 85/205 (41%), Positives = 125/205 (60%), Gaps = 14/205 (6%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRP---RAKDKKLIEEWAVP 171
+W+ RP+SYI+RT WDQ+P+GRWG+S +P++G ++ Y R D +L +
Sbjct: 381 YWSFRPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLSNLTTLRNGDDRL-SMFGEN 439
Query: 172 LKSVEDIYERFRLFCLG-------KLRTNPWSELD-GLQPETKIINEHLEKINTKGFLTI 327
++S+ED+ F + K+ PW+E + G+QPET +I+E L N G LT+
Sbjct: 440 IESIEDVKRVFINYITQTPNVSGKKVTVLPWTEAETGVQPETSLISEQLVWCNENGILTV 499
Query: 328 NSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVE-KTKDRPF-LTYMAV 501
NSQP+VNG S P VGWG PGGY YQKAYLE F + E + L++ ++ P + Y A+
Sbjct: 500 NSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSEKLIDIIEREYPVRVNYHAI 559
Query: 502 NKEGVW-KSNVGQTDVNAVTWGVFP 573
+K+ + K+N +T AVTWGVFP
Sbjct: 560 DKDSSFDKTNSEETTPIAVTWGVFP 584
[109][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 152 bits (383), Expect = 2e-35
Identities = 80/190 (42%), Positives = 113/190 (59%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR SYI+RT WD++P+GRW DS +P++G L Y + + +++ I+ W P KS
Sbjct: 324 FWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDSYG-IGLKGTNEQNIKLWGEP-KS 381
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+ D+ F F G+L PWS+ + E I + L ++N +G TINSQPAVNG +S
Sbjct: 382 IRDLAHIFVKFMQGELARLPWSDTP-ISGEANAIKDKLIELNKRGLFTINSQPAVNGARS 440
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG G+VYQKAYLE LD L+ + + LTY AV+K G ++N +
Sbjct: 441 SHPVYGWGPKNGFVYQKAYLELLVPPYLLDELIARIEKNEDLTYHAVSKTGELRTNT-RD 499
Query: 541 DVNAVTWGVF 570
NA+TWG+F
Sbjct: 500 SPNALTWGIF 509
[110][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 151 bits (381), Expect = 4e-35
Identities = 79/199 (39%), Positives = 116/199 (58%), Gaps = 8/199 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW+NR +YISRT WD++P+GRWGDS +P++G + R K+ +E W P +S
Sbjct: 321 FWSNRKFTYISRTSNWDEFPNGRWGDSRSPAFGEVDLCDGDLIRHSPKRAVELWGKP-QS 379
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
++D+ + F + G L + PWS+ + E ++ + L +N +G LTINSQP VNG S
Sbjct: 380 IDDVIDLFVRYLQGNLSSLPWSDGE-TSKEINVLLDDLLALNRQGILTINSQPCVNGLPS 438
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDR--------PFLTYMAVNKEGV 516
+ GWG G+VYQK YLEFF + L L+ ++ LT+ AVN +G
Sbjct: 439 NHNVHGWGPSNGFVYQKQYLEFFIPAKFLTKLISNIEELNKSYSSNFNTLTFYAVNAQGE 498
Query: 517 WKSNVGQTDVNAVTWGVFP 573
+N + D+NAVTWG+FP
Sbjct: 499 LITNSKEDDINAVTWGIFP 517
[111][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
RepID=A8PV87_BRUMA
Length = 656
Score = 150 bits (380), Expect = 5e-35
Identities = 83/203 (40%), Positives = 116/203 (57%), Gaps = 12/203 (5%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPL 174
FW+ RPKSY+ RT WD++P+GRWG+S +P++ L DY +++ + + + + L
Sbjct: 379 FWSMRPKSYVFRTREWDEFPNGRWGNSSSPAFNDLKDYYLFYLKGQPTRDEQLRMYGERL 438
Query: 175 KSVEDIYERFRLFCLGKLRTN-------PWSEL-DGLQPETKIINEHLEKINTKGFLTIN 330
+++ DI + F F + N PW+E DG++ ET +I + L N+ GFLTIN
Sbjct: 439 ETLADIQKVFVNFITQNINENGVKVSQLPWNEQHDGIRAETSLIKDQLLWCNSNGFLTIN 498
Query: 331 SQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKE 510
SQP++NG S P VGWG PGGY YQKAYLEFF S+ + L L VN +
Sbjct: 499 SQPSINGAPSTDPFVGWGKPGGYCYQKAYLEFFTSQANAEVLWSLLPSYSRLNCHIVNHD 558
Query: 511 GV--WKSNVGQTDVNAVTWGVFP 573
W +N T AVTWGVFP
Sbjct: 559 ATIDW-TNTETTMPIAVTWGVFP 580
[112][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 149 bits (377), Expect = 1e-34
Identities = 78/197 (39%), Positives = 115/197 (58%), Gaps = 6/197 (3%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR SYISRT GWD++P+GRWGDS +P++G + R K+ E W P ++
Sbjct: 330 FWQNRKYSYISRTSGWDEFPNGRWGDSRSPAFGDIDLSASELLRQSPKRAYELWGCP-QT 388
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+ D+ + + +++ PWS+ + +T ++ + L +N KG T+NSQPA++ +S
Sbjct: 389 LNDLSDIIVSYLNNEVKALPWSD-GPIGEDTTVLKDALIALNRKGLFTLNSQPALSAVRS 447
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVE-----KTKDR-PFLTYMAVNKEGVWK 522
+ GWG G+VYQK YLEF K+KL L++ KD +TY AV+K G
Sbjct: 448 NDKLYGWGPKNGFVYQKQYLEFLVRKDKLKELLDIVEKHNAKDTYGLITYYAVDKSGNLH 507
Query: 523 SNVGQTDVNAVTWGVFP 573
+N D+NAVTWGVFP
Sbjct: 508 TNSKNDDINAVTWGVFP 524
[113][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 149 bits (376), Expect = 2e-34
Identities = 79/194 (40%), Positives = 115/194 (59%), Gaps = 3/194 (1%)
Frame = +1
Query: 1 FWANRPKSYISRTIGW--DQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPL 174
FW RP SY++RT W D++P+GR+GDS +P++G L R KK +E W+ P
Sbjct: 333 FWKRRPYSYVARTSQWAMDEFPNGRFGDSSSPAFGDLDLCGSTLIRQSGKKSLELWSTP- 391
Query: 175 KSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGE 354
K++ED+ + + G+++ PWS+ L E I +HL +N K +TINSQP +NG
Sbjct: 392 KTIEDVSQLVISYLTGQIKCLPWSDTS-LDEEIDPILDHLLDLNRKMIITINSQPQINGI 450
Query: 355 KSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAV-NKEGVWKSNV 531
+S+ GWG GYVYQK YLEF EK++ L ++ LTY AV NK+ + ++
Sbjct: 451 RSNHKVHGWGPKDGYVYQKQYLEFLLPNEKVEKLEKQLAGNEMLTYFAVDNKDNLKSNHP 510
Query: 532 GQTDVNAVTWGVFP 573
+ NAVTWG+FP
Sbjct: 511 DGSKANAVTWGIFP 524
[114][TOP]
>UniRef100_A8XGR9 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis briggsae
RepID=A8XGR9_CAEBR
Length = 724
Score = 148 bits (373), Expect = 3e-34
Identities = 84/215 (39%), Positives = 126/215 (58%), Gaps = 24/215 (11%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRP---RAKDKKLIEEWAVP 171
+W+ RP+SYI+RT WDQ+P+GRWG+S +P++G ++ Y R D +L +
Sbjct: 431 YWSFRPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLSNLTTLRNGDDRL-SMFGEN 489
Query: 172 LKSVEDIYERFRLFCLG-------KLRTNPWSELD-GLQPETKIINEHLEKINTKGFLTI 327
++S+ED+ F + K+ PW+E + G+QPET +I+E L N G LT+
Sbjct: 490 IESIEDVKRVFINYITQTPNVSGKKVTVLPWTEAETGVQPETSLISEQLVWCNENGILTV 549
Query: 328 NSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVE-KTKDRPF-LTYMAV 501
NSQP+VNG S P VGWG PGGY YQKAYLE F + E + L++ ++ P + Y A+
Sbjct: 550 NSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSEKLIDIIEREYPVRVNYHAI 609
Query: 502 NKE-----------GVWKSNVGQTDVNAVTWGVFP 573
+K+ ++++N +T AVTWGVFP
Sbjct: 610 DKDVSYILNSHDSMQIFRTNSEETTPIAVTWGVFP 644
[115][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 147 bits (370), Expect = 8e-34
Identities = 80/194 (41%), Positives = 111/194 (57%), Gaps = 3/194 (1%)
Frame = +1
Query: 1 FWANRPKSYISRTIGW--DQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPL 174
FW RP SY++RT W D++P+GR+GDS +P++G L R K +E W+ P
Sbjct: 333 FWKRRPYSYVARTSQWAVDEFPNGRFGDSSSPAFGDLDLCGSDLIRQSANKCLELWSTPT 392
Query: 175 KSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGE 354
S+ D+ + G L+ PWS++ + E I HL ++N +TINSQP VNG
Sbjct: 393 -SINDVAFLVINYLNGNLKCLPWSDIT-INDEINPIKAHLIELNQHSIITINSQPQVNGI 450
Query: 355 KSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSN-V 531
+S+ GWG GYVYQK YLEF K KL L++ K+ FLTY A++ +G SN
Sbjct: 451 RSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHP 510
Query: 532 GQTDVNAVTWGVFP 573
+ NAVTWG+FP
Sbjct: 511 DNSKSNAVTWGIFP 524
[116][TOP]
>UniRef100_B5VIK4 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VIK4_YEAS6
Length = 411
Score = 147 bits (370), Expect = 8e-34
Identities = 80/194 (41%), Positives = 111/194 (57%), Gaps = 3/194 (1%)
Frame = +1
Query: 1 FWANRPKSYISRTIGW--DQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPL 174
FW RP SY++RT W D++P+GR+GDS +P++G L R K +E W+ P
Sbjct: 144 FWKRRPYSYVARTSQWAVDEFPNGRFGDSSSPAFGDLDLCGSDLIRQSANKCLELWSTPT 203
Query: 175 KSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGE 354
S+ D+ + G L+ PWS++ + E I HL ++N +TINSQP VNG
Sbjct: 204 -SINDVAFLVINYLNGNLKCLPWSDIP-INDEINPIKAHLIELNQHSIITINSQPQVNGI 261
Query: 355 KSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSN-V 531
+S+ GWG GYVYQK YLEF K KL L++ K+ FLTY A++ +G SN
Sbjct: 262 RSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHP 321
Query: 532 GQTDVNAVTWGVFP 573
+ NAVTWG+FP
Sbjct: 322 DNSKSNAVTWGIFP 335
[117][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 147 bits (370), Expect = 8e-34
Identities = 80/194 (41%), Positives = 111/194 (57%), Gaps = 3/194 (1%)
Frame = +1
Query: 1 FWANRPKSYISRTIGW--DQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPL 174
FW RP SY++RT W D++P+GR+GDS +P++G L R K +E W+ P
Sbjct: 333 FWKRRPYSYVARTSQWAVDEFPNGRFGDSSSPAFGDLDLCGSDLIRQSANKCLELWSTPT 392
Query: 175 KSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGE 354
S+ D+ + G L+ PWS++ + E I HL ++N +TINSQP VNG
Sbjct: 393 -SINDVAFLVINYLNGNLKCLPWSDIP-INDEINPIKAHLIELNQHSIITINSQPQVNGI 450
Query: 355 KSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSN-V 531
+S+ GWG GYVYQK YLEF K KL L++ K+ FLTY A++ +G SN
Sbjct: 451 RSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHP 510
Query: 532 GQTDVNAVTWGVFP 573
+ NAVTWG+FP
Sbjct: 511 DNSKSNAVTWGIFP 524
[118][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 147 bits (370), Expect = 8e-34
Identities = 80/194 (41%), Positives = 111/194 (57%), Gaps = 3/194 (1%)
Frame = +1
Query: 1 FWANRPKSYISRTIGW--DQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPL 174
FW RP SY++RT W D++P+GR+GDS +P++G L R K +E W+ P
Sbjct: 333 FWKRRPYSYVARTSQWAVDEFPNGRFGDSSSPAFGDLDLCGSDLIRQSANKCLELWSTPT 392
Query: 175 KSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGE 354
S+ D+ + G L+ PWS++ + E I HL ++N +TINSQP VNG
Sbjct: 393 -SINDVAFLVINYLNGNLKCLPWSDIP-INDEINPIKAHLIELNQHSIITINSQPQVNGI 450
Query: 355 KSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSN-V 531
+S+ GWG GYVYQK YLEF K KL L++ K+ FLTY A++ +G SN
Sbjct: 451 RSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHP 510
Query: 532 GQTDVNAVTWGVFP 573
+ NAVTWG+FP
Sbjct: 511 DNSKSNAVTWGIFP 524
[119][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 145 bits (366), Expect = 2e-33
Identities = 85/194 (43%), Positives = 110/194 (56%), Gaps = 3/194 (1%)
Frame = +1
Query: 1 FWANRPKSYISRTIGW--DQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPL 174
FW RP SY++RT W D++P+GR+GDS +P++G L R KK +E W+ P
Sbjct: 332 FWQRRPYSYVARTSQWSVDEFPNGRFGDSSSPAFGDLDLCGASLIRQSGKKSLELWSAP- 390
Query: 175 KSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGE 354
S+EDI + + G+L+ PWS+ L E I L +N K +TINSQP +NG
Sbjct: 391 NSMEDIAQLVINYLRGELKYLPWSDTS-LNHEVDDILPELVTLNQKLIITINSQPQLNGV 449
Query: 355 KSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSN-V 531
KS P GWG GYVYQK YLEF KEKL L + + LTY AV+ G +N
Sbjct: 450 KSSHPVHGWGPRDGYVYQKMYLEFLLPKEKLSKLHDCLVNDVMLTYFAVDHNGNLTTNHQ 509
Query: 532 GQTDVNAVTWGVFP 573
T NAVTWG+FP
Sbjct: 510 DGTRANAVTWGIFP 523
[120][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 144 bits (362), Expect = 6e-33
Identities = 79/192 (41%), Positives = 115/192 (59%), Gaps = 1/192 (0%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW R +S+ISRT WD++P+GRWGDS +P++G D + + D ++ W P ++
Sbjct: 332 FWKTRSQSFISRTEQWDEFPNGRWGDSRSPAFGEF-DPKHHGLKQTDAEIRALWGSP-EN 389
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
+ D+ F +C KL PWS++ L E+ II + L ++N +G LTINSQP V S
Sbjct: 390 IRDLGNVFAAYCERKLACLPWSDIP-LSGESAIIADKLAELNRQGILTINSQPPVCAAPS 448
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
P GWG GYV+QKAYLEFF +++ +L+E + Y + EG ++N G+
Sbjct: 449 TDPLFGWGPAHGYVFQKAYLEFFMHPDQVKSLLEVIPSFKTVQYYITDYEGSLETN-GEL 507
Query: 541 DV-NAVTWGVFP 573
DV +AVTWGVFP
Sbjct: 508 DVPSAVTWGVFP 519
[121][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 143 bits (361), Expect = 8e-33
Identities = 83/195 (42%), Positives = 113/195 (57%), Gaps = 4/195 (2%)
Frame = +1
Query: 1 FWANRPKSYISRTIGW--DQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPL 174
FW RP SY++RT W D++P+GR+GDS +P+YG L R KK IE W+ P
Sbjct: 335 FWQKRPYSYVARTSLWNEDEFPNGRFGDSSSPAYGDLDLCGHSLIRQSVKKSIELWSTP- 393
Query: 175 KSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGE 354
++++D+ + GKL+ PWS++ L E I +HL +N TINSQP VNG+
Sbjct: 394 QTLDDMSNLVTSYLEGKLKCLPWSDVP-LNHEVDDILKHLIDLNKHHIFTINSQPKVNGK 452
Query: 355 KSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDR-PFLTYMAVNKEGVWKSNV 531
S P VGWG GYVYQK YLEF +EKL E ++ LTY A++ + +N
Sbjct: 453 PSTDPVVGWGPTKGYVYQKEYLEFLLPREKLPLFQEICQEHSDHLTYFAIDSQDNLATNH 512
Query: 532 GQ-TDVNAVTWGVFP 573
+ + NAVTWGVFP
Sbjct: 513 PEDSRANAVTWGVFP 527
[122][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 140 bits (352), Expect = 9e-32
Identities = 82/200 (41%), Positives = 106/200 (53%), Gaps = 9/200 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGW--DQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPL 174
FW RP SY++RT W D++P+GR+GDS +P++G L R ++ +E W+ P
Sbjct: 331 FWQKRPYSYVARTSQWTADEFPNGRFGDSSSPAFGDLDLLGSTSIRQSPQRALELWSTPT 390
Query: 175 KSVEDIYERFRLFCLGKLRTNPWS------ELDGLQPETKIINEHLEKINTKGFLTINSQ 336
K DI + GKL+ PW E+D P+ +N+H+ LT+NSQ
Sbjct: 391 K-FSDIAALVIDYLHGKLKCLPWCDVALNHEVDTTMPQLLDLNKHM-------ILTLNSQ 442
Query: 337 PAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGV 516
P VNG S VGWG GYVYQK YLEF K KL L + D P LTY AV+
Sbjct: 443 PRVNGASSADKIVGWGPNNGYVYQKQYLEFLLPKSKLSQLRDFVNDMPSLTYFAVDSADE 502
Query: 517 WKSN-VGQTDVNAVTWGVFP 573
SN T NAVTWG+FP
Sbjct: 503 LHSNHPDDTAANAVTWGIFP 522
[123][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 139 bits (350), Expect = 2e-31
Identities = 82/195 (42%), Positives = 109/195 (55%), Gaps = 4/195 (2%)
Frame = +1
Query: 1 FWANRPKSYISRTIGW--DQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPL 174
FW RP SY++RT W D++P+GR+GDS +P+YG L R ++ +E W+ P
Sbjct: 334 FWQRRPYSYVARTSQWSADEFPNGRFGDSSSPAYGDLDLCGHTVLRQTYQRSLELWSTP- 392
Query: 175 KSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGE 354
+++ D+ + G L+ PWS++ L E + + L ++N LTINSQP VNG
Sbjct: 393 RTLLDLAALVISYLKGDLKCLPWSDVP-LHQEADALLDSLIRLNEHLVLTINSQPKVNGA 451
Query: 355 KSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDAL-VEKTKDRPFLTYMAVNKEGVWKSN- 528
S P VGWG GYVYQK YLEF K L A T D P LTY AV+ + SN
Sbjct: 452 PSADPIVGWGPANGYVYQKQYLEFLLPKHHLPAFHAALTADFPTLTYFAVDADDNLASNH 511
Query: 529 VGQTDVNAVTWGVFP 573
T NAVTWG+FP
Sbjct: 512 PDDTQANAVTWGIFP 526
[124][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 138 bits (348), Expect = 3e-31
Identities = 67/146 (45%), Positives = 92/146 (63%), Gaps = 9/146 (6%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKK--LIEEWAVPL 174
FWA+RPKSYI RT WD +P+GRWG+S +P++G L DY ++K K L++ W L
Sbjct: 370 FWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALLQMWGEEL 429
Query: 175 KSVEDIYERFRLF-------CLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINS 333
S E ++E F + C K+ PW++ + L ET ++ + LEK+N +G LTINS
Sbjct: 430 LSEESVFEVFTFYITAQSNRCGQKVLCLPWND-EPLAQETNLLKDELEKVNRRGVLTINS 488
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQK 411
QP +NG+ S P VGWG GGYVYQK
Sbjct: 489 QPNINGKPSTDPIVGWGPAGGYVYQK 514
[125][TOP]
>UniRef100_C9S7I3 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S7I3_9PEZI
Length = 312
Score = 138 bits (347), Expect = 3e-31
Identities = 79/191 (41%), Positives = 102/191 (53%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW R KSYI RT WD++P+GRWGDS +P++G L Y ++ I++W P ++
Sbjct: 47 FWKGRNKSYILRTQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGTNEQN-IKKWGEP-QT 104
Query: 181 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 360
V+DI L TN E I E L +N +G +TINSQPAVNG KS
Sbjct: 105 VQDIAT------LESPLTN----------EADPIREDLIALNKRGIITINSQPAVNGVKS 148
Query: 361 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 540
GWG GYVYQK+YLE + ++ + + P +TY AV K G K N
Sbjct: 149 SHAVHGWGPKNGYVYQKSYLEMLVHPDLYPEIISRIEKHPDMTYYAVTKSGNLKYNAPSD 208
Query: 541 DVNAVTWGVFP 573
NAVTWGVFP
Sbjct: 209 GPNAVTWGVFP 219
[126][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 136 bits (342), Expect = 1e-30
Identities = 77/199 (38%), Positives = 114/199 (57%), Gaps = 8/199 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALT-DYQFMRPRAKDKKLIEE---WAV 168
FW NR KS+I RT WD++P+GR G+ + +YG +++ ++K + W
Sbjct: 302 FWRNRQKSFIQRTSSWDEFPNGRLGNQASAAYGDFELNFRSYSKETQEKVAADRRRMWGD 361
Query: 169 PLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVN 348
+ + + + F F G+++ PW + ET I + L ++N LTINSQP VN
Sbjct: 362 HVPNGDHVRRVFTDFIKGEVKRLPWCTEPPTE-ETLFIQKQLIRLNQCNMLTINSQPRVN 420
Query: 349 GEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF--LTYMAVNKEG-VW 519
G S P VGWG GG+VYQKAY+EFFC + +L+ L+ + + ++YMAV +G
Sbjct: 421 GALSTDPYVGWGPAGGFVYQKAYVEFFCPEGQLEQLIRGIEAEKYDSISYMAVTADGSKV 480
Query: 520 KSNV-GQTDVNAVTWGVFP 573
+SN+ Q VNAVTWGVFP
Sbjct: 481 RSNIPPQGQVNAVTWGVFP 499
[127][TOP]
>UniRef100_A7TRT4 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TRT4_VANPO
Length = 645
Score = 135 bits (340), Expect = 2e-30
Identities = 75/187 (40%), Positives = 106/187 (56%), Gaps = 5/187 (2%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKD--KKLIEEWAVPLKSVEDIYER 201
+ R WD++P+GR+GDS +P+YG + Y P K KK + W P KSV D+
Sbjct: 392 LGRNATWDEFPNGRFGDSRSPAYGEIDGYG---PTLKVGIKKAYDLWGTP-KSVIDLKSV 447
Query: 202 FRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGW 381
F + G + PW +L GL PET +I E L ++N +G+LT+ SQPA N S GW
Sbjct: 448 FIKYLEGSISALPWCDL-GLSPETALIQEELIQLNQRGYLTLASQPATNASPSTDKIFGW 506
Query: 382 GGPGGYVYQKAYLEFFCSKEKLDALVEKTKD---RPFLTYMAVNKEGVWKSNVGQTDVNA 552
G GYVYQKA++E F K++ +A+V+ D R +Y + G ++SN+ N
Sbjct: 507 GPKNGYVYQKAFVEMFILKKQWEAIVKPKLDHYPRGKFSYYVGDSSGSFESNLETNSSNV 566
Query: 553 VTWGVFP 573
VTWGVFP
Sbjct: 567 VTWGVFP 573
[128][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TTE9_VANPO
Length = 612
Score = 131 bits (330), Expect = 3e-29
Identities = 79/199 (39%), Positives = 111/199 (55%), Gaps = 8/199 (4%)
Frame = +1
Query: 1 FWANRPKSYISRTIGW--DQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPL 174
FW +RP SY++RT W D++P+GR+GDS +P++G L R ++ +E WA+P
Sbjct: 327 FWKSRPYSYVARTSQWAADEFPNGRFGDSSSPAFGDLDLCGSTLLRQSAQRSLELWAMP- 385
Query: 175 KSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFL-TINSQPAVNG 351
S+ D+ + G+LR PWS+ + E +I L +N + + TINSQP VNG
Sbjct: 386 SSIRDVAMLVVAYLQGELRCLPWSDTP-VSSEVDVIRRQLIALNEQQLIVTINSQPQVNG 444
Query: 352 EKSDSPTVGWGGPGGYVYQKAYLEFFCSK---EKLDALVEKTKD-RPFLTYMAVNKEGVW 519
+S+ GWG GYVYQK YLEF + E+L + KT + LTY+A + G W
Sbjct: 445 LRSNVKGFGWGPSDGYVYQKQYLEFLLPRARFERLQQELSKTNETTSSLTYLAADSHGGW 504
Query: 520 KSNVGQ-TDVNAVTWGVFP 573
SN AVTWGVFP
Sbjct: 505 WSNQPDGAKATAVTWGVFP 523
[129][TOP]
>UniRef100_B6JY06 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6JY06_SCHJY
Length = 626
Score = 131 bits (329), Expect = 4e-29
Identities = 70/182 (38%), Positives = 102/182 (56%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 207
+ R WD Y +GR+GD +P+YG + Y A ++ L + W P+ +DI F+
Sbjct: 376 LGREATWDDYTNGRFGDPRSPAYGNIDGYGPSLHFAPEESL-KLWGYPVDE-DDITNIFK 433
Query: 208 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 387
LG+ PW + ++ ETK I + L K+ K + T+ SQPAVN S GWG
Sbjct: 434 RHVLGETTAIPWID-QPVEAETKTIGDKLAKLIEKKWWTVGSQPAVNAAPSSHAIFGWGP 492
Query: 388 PGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGV 567
GG+V+QKA++E F S +AL ++ D P +TY+A N +G +K+N NAVTWGV
Sbjct: 493 RGGWVFQKAFVEMFMSTMDFEALAQRLHDNPQITYLAGNNKGEFKTNASLDSANAVTWGV 552
Query: 568 FP 573
FP
Sbjct: 553 FP 554
[130][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 130 bits (328), Expect = 6e-29
Identities = 76/196 (38%), Positives = 108/196 (55%), Gaps = 5/196 (2%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALT-DYQFMRPRAKDKKLIEEWAVPLK 177
FW NR KS+I RT WD++P+GR G+ + +YG +++ +DK +
Sbjct: 302 FWRNRQKSFIQRTSSWDEFPNGRLGNQASAAYGDFELNFRSYSKETQDKVFTD------- 354
Query: 178 SVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEK 357
F G+++ PW + ET I + L ++N LTINSQP VNG
Sbjct: 355 -----------FIKGEVKRLPWCTEPPTE-ETLFIQKQLIRLNQCNMLTINSQPRVNGAL 402
Query: 358 SDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF--LTYMAVNKEG-VWKSN 528
S P VGWG GG+VYQKAY+EFFC + +L+ L+ + + ++YMAV +G +SN
Sbjct: 403 STDPYVGWGPAGGFVYQKAYVEFFCPEGQLEQLIRGIEAEKYDSISYMAVTADGSKVRSN 462
Query: 529 V-GQTDVNAVTWGVFP 573
+ Q VNAVTWGVFP
Sbjct: 463 IPPQGQVNAVTWGVFP 478
[131][TOP]
>UniRef100_Q752W6 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q752W6_ASHGO
Length = 635
Score = 129 bits (324), Expect = 2e-28
Identities = 70/184 (38%), Positives = 102/184 (55%), Gaps = 2/184 (1%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 207
+ R WD++P+GR+GDS +P+YG + Y + +KK + W P ++ DI F
Sbjct: 383 LGRDATWDEFPNGRFGDSRSPAYGEIDGYG-PSLKVSNKKAYQIWGYP-STLNDIKSLFI 440
Query: 208 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 387
+ G + PW +L GL PET +I E L +N +GFLT+ SQPA N S GWG
Sbjct: 441 GYLEGSIEALPWCDL-GLSPETALIQEELIGLNQRGFLTLASQPATNSTPSADKIFGWGP 499
Query: 388 PGGYVYQKAYLEFFCSKEKLDALVEKTKDRP--FLTYMAVNKEGVWKSNVGQTDVNAVTW 561
PGG VYQKA++E F K + +A ++ + P +Y + G + SN+ + VTW
Sbjct: 500 PGGVVYQKAFVELFVEKARWEAELKPRLEGPDSKFSYYFGDSAGSFASNMAPESSSVVTW 559
Query: 562 GVFP 573
GVFP
Sbjct: 560 GVFP 563
[132][TOP]
>UniRef100_Q5A5S8 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5A5S8_CANAL
Length = 640
Score = 129 bits (324), Expect = 2e-28
Identities = 71/191 (37%), Positives = 106/191 (55%), Gaps = 5/191 (2%)
Frame = +1
Query: 19 KSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYE 198
K + + WD +P+GR+GDS +P+YG + Y + +W P +S+ D+ +
Sbjct: 380 KGALGKDAIWDDFPNGRFGDSNSPAYGEIDGYGPTLKIHTPAEASTKWGTP-ESIADLTQ 438
Query: 199 RFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVG 378
F + GK+ PW++ L PET +I E L ++N KG+ ++ SQPAVNG KS G
Sbjct: 439 VFINYLSGKVDVVPWAD-SSLSPETALIQEELFQLNEKGWFSVASQPAVNGCKSTDNIFG 497
Query: 379 WGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVG-----QTD 543
WG G +YQK+++E F KE L+ K + +TY NK+G KSN+ +
Sbjct: 498 WGPRNGIIYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVGNKDGEIKSNLPIGPNVKLS 557
Query: 544 VNAVTWGVFPA 576
NAVTWGVFP+
Sbjct: 558 KNAVTWGVFPS 568
[133][TOP]
>UniRef100_C4YKV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=C4YKV3_CANAL
Length = 640
Score = 129 bits (324), Expect = 2e-28
Identities = 71/191 (37%), Positives = 106/191 (55%), Gaps = 5/191 (2%)
Frame = +1
Query: 19 KSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYE 198
K + + WD +P+GR+GDS +P+YG + Y + +W P +S+ D+ +
Sbjct: 380 KGALGKDAIWDDFPNGRFGDSNSPAYGEIDGYGPTLKIHTPAEASTKWGTP-ESIADLTQ 438
Query: 199 RFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVG 378
F + GK+ PW++ L PET +I E L ++N KG+ ++ SQPAVNG KS G
Sbjct: 439 VFINYLSGKVDVVPWAD-SSLSPETALIQEELFQLNEKGWFSVASQPAVNGCKSTDNIFG 497
Query: 379 WGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVG-----QTD 543
WG G +YQK+++E F KE L+ K + +TY NK+G KSN+ +
Sbjct: 498 WGPRNGIIYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVGNKDGEIKSNLPIGPNVKLS 557
Query: 544 VNAVTWGVFPA 576
NAVTWGVFP+
Sbjct: 558 KNAVTWGVFPS 568
[134][TOP]
>UniRef100_Q6FNS2 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FNS2_CANGA
Length = 645
Score = 129 bits (323), Expect = 2e-28
Identities = 67/191 (35%), Positives = 108/191 (56%), Gaps = 3/191 (1%)
Frame = +1
Query: 10 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 189
+R + R WD++P+GR+GDS +P+YG + Y + +K+ E W P S+ D
Sbjct: 386 SRGSGVLGRDATWDEFPNGRFGDSRSPAYGEIDGYG-PSLKVSNKRAYELWGSPT-SIRD 443
Query: 190 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 369
+ F + G +++ PW +L GL PET +I E L ++N +G+LT+ SQP N S
Sbjct: 444 LKAVFVKYLEGSIQSLPWCDL-GLSPETALIQEELIQLNYRGYLTLASQPCTNASSSTDK 502
Query: 370 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD---RPFLTYMAVNKEGVWKSNVGQT 540
GWG G+VYQKA++E F +++ +++ D R +Y A + +G +++N+
Sbjct: 503 IFGWGPSKGHVYQKAFIEMFVHRQQWKTILKPKLDYYGRRKFSYYAGDSKGSFETNLDPH 562
Query: 541 DVNAVTWGVFP 573
N VTWGVFP
Sbjct: 563 SSNVVTWGVFP 573
[135][TOP]
>UniRef100_B2WHR5 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WHR5_PYRTR
Length = 653
Score = 128 bits (322), Expect = 3e-28
Identities = 69/181 (38%), Positives = 99/181 (54%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 207
+ R WD +P+GRWGD+ +P++G + Y + ++ W P++ +DI FR
Sbjct: 404 LGREATWDDFPNGRWGDARSPAFGEIDGYG-PTLHVSTPQALKLWGYPVEK-KDISTLFR 461
Query: 208 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 387
G L PWSE GL PET I+ L +N KG+ T+ SQPAVNG KS P GWG
Sbjct: 462 RHIEGDLEAIPWSE-QGLSPETSTISAQLLALNAKGWWTVASQPAVNGVKSTDPIFGWGP 520
Query: 388 PGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGV 567
GYV+QK ++EFF + A K + +T+ A N G ++++ + VN VTWG
Sbjct: 521 KNGYVFQKPFVEFFIPAAEFQAFKPKLQAHDQVTWFAGNAAGAFEAS-QEDGVNPVTWGT 579
Query: 568 F 570
F
Sbjct: 580 F 580
[136][TOP]
>UniRef100_B2B6X0 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B6X0_PODAN
Length = 691
Score = 128 bits (322), Expect = 3e-28
Identities = 72/195 (36%), Positives = 106/195 (54%), Gaps = 13/195 (6%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 207
+ R WD +P+GRWGD+ +P+YG + Y + + + W P ++ EDI F
Sbjct: 428 LGREATWDDFPNGRWGDARSPAYGQIDGYG-VSLHVTVAQALRIWGTP-RTTEDINNVFI 485
Query: 208 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 387
G+L T PWSE +G PET I + L K+N+KG+ ++ SQPAVNG +S PT GWG
Sbjct: 486 RHLKGELTTIPWSE-EGFSPETDKIRDQLIKLNSKGWWSLASQPAVNGLRSSDPTFGWGP 544
Query: 388 PGGYVYQKAYLEFFCSKEKLDALVEKTKD---RPFLTYMAVNKEGVWKSN---------- 528
G+V+QKA++EFF L +K + + + + A+N G + S+
Sbjct: 545 ANGFVFQKAFVEFFIPSADWKVLEQKLRHPDLKDDVCFYAINAAGDFVSSDTAGSLEAEG 604
Query: 529 VGQTDVNAVTWGVFP 573
+ NAVTWGVFP
Sbjct: 605 EKEASTNAVTWGVFP 619
[137][TOP]
>UniRef100_Q6CR34 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CR34_KLULA
Length = 649
Score = 128 bits (321), Expect = 4e-28
Identities = 71/187 (37%), Positives = 111/187 (59%), Gaps = 5/187 (2%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAK--DKKLIEEWAVPLKSVEDIYER 201
+ R + WD++P+GR+GDS +P+YG + Y P K + E W P+ S+EDI
Sbjct: 397 LGRNVTWDEFPNGRFGDSRSPAYGEIDGYG---PSLKVCNSTAYELWDHPV-SLEDIKNI 452
Query: 202 FRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGW 381
F + G ++ PWS+L GL ET I E L ++N +G+L++ SQPA NG +S GW
Sbjct: 453 FIRYLEGSMKALPWSDL-GLSAETAFIQEELIELNQRGYLSLASQPATNGSQSTDNIFGW 511
Query: 382 GGPGGYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSNVGQTDVNA 552
G G +YQKA++E F KE+ + +++ ++K+ F Y+ + G +++N+ NA
Sbjct: 512 GPANGLIYQKAFVEIFVRKEEWNQVLKPKIESKNGEFSYYLG-DYTGYFETNLQPKSSNA 570
Query: 553 VTWGVFP 573
VTWGVFP
Sbjct: 571 VTWGVFP 577
[138][TOP]
>UniRef100_Q0UB79 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UB79_PHANO
Length = 543
Score = 128 bits (321), Expect = 4e-28
Identities = 69/181 (38%), Positives = 99/181 (54%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 207
+ R WD +P+GRWGD+ +P++G + Y + ++ W P+ +DI FR
Sbjct: 294 LGREATWDDFPNGRWGDARSPAFGEIDGYG-PTLHVSTTQALKLWGHPVDK-QDISALFR 351
Query: 208 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 387
G+L PWSE GL PET I + L +N KG+ T+ SQPAVNG +S P GWG
Sbjct: 352 KHLEGELEALPWSE-QGLSPETSTIAKQLLALNAKGWWTVASQPAVNGVRSTDPVFGWGP 410
Query: 388 PGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGV 567
GYV+QK ++EFF + AL + +TY A N G ++++ + VN VTWG
Sbjct: 411 KNGYVFQKPFVEFFLPAAEFHALRTRLDAHDQVTYFAGNANGDFEAS-SEESVNPVTWGT 469
Query: 568 F 570
F
Sbjct: 470 F 470
[139][TOP]
>UniRef100_Q6CEM7 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CEM7_YARLI
Length = 625
Score = 127 bits (319), Expect = 6e-28
Identities = 71/185 (38%), Positives = 102/185 (55%), Gaps = 3/185 (1%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 207
+ R WD +P+GR+GDS +P++G + Y + +E W P+ D+ + F
Sbjct: 373 VGREAVWDDFPNGRFGDSSSPAFGEIDGYG-PSIHVPPARALELWGYPVDDA-DLSKLFA 430
Query: 208 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 387
+GKL PWS+ L PET +I E L ++N KG T+ SQPA N KSD GWG
Sbjct: 431 DTIVGKLPFMPWSD-QTLSPETMLIQEQLMELNQKGIWTVASQPACNALKSDDNIFGWGP 489
Query: 388 PGGYVYQKAYLEFFCSKE---KLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVT 558
GGYV+QK++ EFF S E KL L++ +D ++Y + + +NV + N VT
Sbjct: 490 KGGYVFQKSFAEFFISPEQWKKLKPLLDAQED--LVSYYVAKSDKLVDTNVSERASNGVT 547
Query: 559 WGVFP 573
WGVFP
Sbjct: 548 WGVFP 552
[140][TOP]
>UniRef100_C5DPF1 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5DPF1_ZYGRC
Length = 650
Score = 127 bits (318), Expect = 8e-28
Identities = 70/186 (37%), Positives = 106/186 (56%), Gaps = 5/186 (2%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 207
+ R WD++P+GR+GD+ +P++G + Y + +KK E W P K+++D+ F
Sbjct: 396 LGRDATWDEFPNGRFGDTRSPAFGEIDGYG-PTLKVSNKKAYELWGQP-KTIQDLQIIFI 453
Query: 208 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 387
+ G + PW +L GL PET +I E L ++N +GFLT+ SQPA NG S + GWG
Sbjct: 454 KYLEGSIDALPWCDL-GLSPETALIQEELIQLNERGFLTLASQPATNGSPSTNKIFGWGP 512
Query: 388 PGGYVYQKAYLEFFCSKE-----KLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVNA 552
G VYQKA++E F K + +E+ R LTY A + +G +++N+ N
Sbjct: 513 AYGVVYQKAFIEMFVPKNIWENGNMKKAIEQ-YGRAKLTYYANDSQGNFETNLESNSSNV 571
Query: 553 VTWGVF 570
VTWGVF
Sbjct: 572 VTWGVF 577
[141][TOP]
>UniRef100_Q6BM19 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=Q6BM19_DEBHA
Length = 642
Score = 125 bits (315), Expect = 2e-27
Identities = 71/195 (36%), Positives = 106/195 (54%), Gaps = 9/195 (4%)
Frame = +1
Query: 19 KSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYE 198
K + + WD +P+GR+GDS +P+YG + Y ++ I +W P +SV +I +
Sbjct: 377 KGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPTLKIYSPEEAIHKWGAP-ESVNEIIK 435
Query: 199 RFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVG 378
F + GK+ + PW + L PET +I E L ++N KG+ ++ SQPAVNG S G
Sbjct: 436 VFVSYLSGKIDSLPWVDA-ALSPETALIQEELFEVNNKGWFSLASQPAVNGCLSSDKIFG 494
Query: 379 WGGPGGYVYQKAYLEFFCSKE----KLDALVEKTKDRPFLTYMAVNKEGVWKSNVG---- 534
WG G +YQKA++E F K+ KL ++K D +TY + EG SN+
Sbjct: 495 WGPGNGIIYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTITYYCGDAEGRLTSNLNIDQE 554
Query: 535 -QTDVNAVTWGVFPA 576
NA+TWGVFP+
Sbjct: 555 HYNSKNAITWGVFPS 569
[142][TOP]
>UniRef100_UPI00003BE162 hypothetical protein DEHA0F09867g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE162
Length = 642
Score = 125 bits (314), Expect = 2e-27
Identities = 71/194 (36%), Positives = 105/194 (54%), Gaps = 9/194 (4%)
Frame = +1
Query: 19 KSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYE 198
K + + WD +P+GR+GDS +P+YG + Y ++ I +W P +SV +I +
Sbjct: 377 KGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPTLKIYSPEEAIHKWGAP-ESVNEIIK 435
Query: 199 RFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVG 378
F + GK+ + PW + L PET +I E L ++N KG+ ++ SQPAVNG S G
Sbjct: 436 VFVSYLSGKIDSLPWVDA-ALSPETALIQEELFEVNNKGWFSLASQPAVNGCLSSDKIFG 494
Query: 379 WGGPGGYVYQKAYLEFFCSKE----KLDALVEKTKDRPFLTYMAVNKEGVWKSNVG---- 534
WG G +YQKA++E F K+ KL ++K D +TY + EG SN+
Sbjct: 495 WGPGNGIIYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTITYYCGDAEGRLTSNLNIDQE 554
Query: 535 -QTDVNAVTWGVFP 573
NA+TWGVFP
Sbjct: 555 HYNSKNAITWGVFP 568
[143][TOP]
>UniRef100_B9WCV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WCV3_CANDC
Length = 640
Score = 125 bits (314), Expect = 2e-27
Identities = 68/191 (35%), Positives = 106/191 (55%), Gaps = 5/191 (2%)
Frame = +1
Query: 19 KSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYE 198
K + + WD +P+GR+GDS +P+YG + Y ++ +W P +S+ D+
Sbjct: 380 KGALGKDAIWDDFPNGRFGDSNSPAYGEIDGYGPTLKIHTPEEASTKWGTP-ESLADLTR 438
Query: 199 RFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVG 378
F + GK+ PW++ L PET +I E L ++N KG+ ++ SQPA+NG KS G
Sbjct: 439 VFINYLSGKVDVIPWAD-SSLSPETALIQEELFQLNEKGWFSVASQPAINGCKSTDNIFG 497
Query: 379 WGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNV-----GQTD 543
WG G +YQK+++E F KE L+ K + +TY +K+G +SN+ +
Sbjct: 498 WGPRNGTIYQKSFIELFMPKEDWTKLLLKIELDKTVTYYVGDKDGEIRSNLPIGPNAKLS 557
Query: 544 VNAVTWGVFPA 576
NAVTWGVFP+
Sbjct: 558 KNAVTWGVFPS 568
[144][TOP]
>UniRef100_A3LW82 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LW82_PICST
Length = 635
Score = 124 bits (311), Expect = 5e-27
Identities = 71/195 (36%), Positives = 108/195 (55%), Gaps = 9/195 (4%)
Frame = +1
Query: 19 KSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYE 198
K + + WD +P+GR+GDS +P+YG + Y A ++ I +W P +SV DI +
Sbjct: 372 KGALGKEAIWDDFPNGRFGDSNSPAYGEIDGYGPSLKVASPEEAIAKWGSP-ESVGDIAK 430
Query: 199 RFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVG 378
F + GK+ PW++ L ET +I E L +N +G+ ++ SQPAVNG KS G
Sbjct: 431 VFMGYLSGKIDILPWTD-SSLSAETTLIQEELFDLNDRGWFSLASQPAVNGCKSTDRIFG 489
Query: 379 WGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF----LTYMAVNKEGVWKSNV----- 531
WG G VYQKA++E F KE+ ++ ++ + F +TY + EG +SN+
Sbjct: 490 WGPKNGIVYQKAFVEIFVPKEQWESELKSSLKPHFEEKTITYYVGDAEGNIESNLFVGPD 549
Query: 532 GQTDVNAVTWGVFPA 576
NA+TWGVFP+
Sbjct: 550 AHNSKNAITWGVFPS 564
[145][TOP]
>UniRef100_C7GU28 Met12p n=2 Tax=Saccharomyces cerevisiae RepID=C7GU28_YEAS2
Length = 657
Score = 122 bits (307), Expect = 2e-26
Identities = 67/185 (36%), Positives = 105/185 (56%), Gaps = 3/185 (1%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 207
+ R WD++P+GR+GDS +P+YG + Y +K K L E W +P K++ D+ + F
Sbjct: 402 LGRDATWDEFPNGRFGDSRSPAYGEIDGYGPSIKVSKSKAL-ELWGIP-KTIGDLKDIFI 459
Query: 208 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 387
+ G PWS+L GL ET +I E L ++N +G+LT+ SQPA N S GWG
Sbjct: 460 KYLEGSTDAIPWSDL-GLSAETALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGP 518
Query: 388 PGGYVYQKAYLEFFCSKEKLDALVEKTKD---RPFLTYMAVNKEGVWKSNVGQTDVNAVT 558
G +YQKA++E F +++ + ++ D R +Y A + G +++N+ + VT
Sbjct: 519 AKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVT 578
Query: 559 WGVFP 573
WGVFP
Sbjct: 579 WGVFP 583
[146][TOP]
>UniRef100_B5VTD9 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VTD9_YEAS6
Length = 657
Score = 122 bits (307), Expect = 2e-26
Identities = 67/185 (36%), Positives = 105/185 (56%), Gaps = 3/185 (1%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 207
+ R WD++P+GR+GDS +P+YG + Y +K K L E W +P K++ D+ + F
Sbjct: 402 LGRDATWDEFPNGRFGDSRSPAYGEIDGYGPSIKVSKSKAL-ELWGIP-KTIGDLKDIFI 459
Query: 208 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 387
+ G PWS+L GL ET +I E L ++N +G+LT+ SQPA N S GWG
Sbjct: 460 KYLEGSTDAIPWSDL-GLSAETALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGP 518
Query: 388 PGGYVYQKAYLEFFCSKEKLDALVEKTKD---RPFLTYMAVNKEGVWKSNVGQTDVNAVT 558
G +YQKA++E F +++ + ++ D R +Y A + G +++N+ + VT
Sbjct: 519 AKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVT 578
Query: 559 WGVFP 573
WGVFP
Sbjct: 579 WGVFP 583
[147][TOP]
>UniRef100_B3LL40 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LL40_YEAS1
Length = 657
Score = 122 bits (307), Expect = 2e-26
Identities = 67/185 (36%), Positives = 105/185 (56%), Gaps = 3/185 (1%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 207
+ R WD++P+GR+GDS +P+YG + Y +K K L E W +P K++ D+ + F
Sbjct: 402 LGRDATWDEFPNGRFGDSRSPAYGEIDGYGPSIKVSKSKAL-ELWGIP-KTIGDLKDIFI 459
Query: 208 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 387
+ G PWS+L GL ET +I E L ++N +G+LT+ SQPA N S GWG
Sbjct: 460 KYLEGSTDAIPWSDL-GLSAETALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGP 518
Query: 388 PGGYVYQKAYLEFFCSKEKLDALVEKTKD---RPFLTYMAVNKEGVWKSNVGQTDVNAVT 558
G +YQKA++E F +++ + ++ D R +Y A + G +++N+ + VT
Sbjct: 519 AKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVT 578
Query: 559 WGVFP 573
WGVFP
Sbjct: 579 WGVFP 583
[148][TOP]
>UniRef100_A5DE00 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DE00_PICGU
Length = 642
Score = 122 bits (307), Expect = 2e-26
Identities = 69/195 (35%), Positives = 106/195 (54%), Gaps = 9/195 (4%)
Frame = +1
Query: 19 KSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYE 198
K + + WD +P+GR+GDS +P+YG + Y ++ I +W P +S +DI +
Sbjct: 379 KGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPSLKIHSPQEAIAKWGTP-ESTKDISK 437
Query: 199 RFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVG 378
F + GK+ PW + L ET +I E L ++N KG+ ++ SQP+VNG +S G
Sbjct: 438 VFLNYLSGKINILPWVDAP-LSAETALIQEELFELNDKGWFSLASQPSVNGARSSDKIFG 496
Query: 379 WGGPGGYVYQKAYLEFFCSKE----KLDALVEKTKDRPFLTYMAVNKEGVWKSNV----- 531
WG G+V+QK+++E F KE KL ++ D +TY A + G +SN+
Sbjct: 497 WGPSNGFVFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDITYYAGDSSGKIQSNLPVGPD 556
Query: 532 GQTDVNAVTWGVFPA 576
NAVTWGVFP+
Sbjct: 557 SHNSKNAVTWGVFPS 571
[149][TOP]
>UniRef100_P46151 Methylenetetrahydrofolate reductase 1 n=1 Tax=Saccharomyces
cerevisiae RepID=MTHR1_YEAST
Length = 657
Score = 122 bits (307), Expect = 2e-26
Identities = 67/185 (36%), Positives = 105/185 (56%), Gaps = 3/185 (1%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 207
+ R WD++P+GR+GDS +P+YG + Y +K K L E W +P K++ D+ + F
Sbjct: 402 LGRDATWDEFPNGRFGDSRSPAYGEIDGYGPSIKVSKSKAL-ELWGIP-KTIGDLKDIFI 459
Query: 208 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 387
+ G PWS+L GL ET +I E L ++N +G+LT+ SQPA N S GWG
Sbjct: 460 KYLEGSTDAIPWSDL-GLSAETALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGP 518
Query: 388 PGGYVYQKAYLEFFCSKEKLDALVEKTKD---RPFLTYMAVNKEGVWKSNVGQTDVNAVT 558
G +YQKA++E F +++ + ++ D R +Y A + G +++N+ + VT
Sbjct: 519 AKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVT 578
Query: 559 WGVFP 573
WGVFP
Sbjct: 579 WGVFP 583
[150][TOP]
>UniRef100_UPI000151A866 hypothetical protein PGUG_01501 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151A866
Length = 642
Score = 122 bits (306), Expect = 2e-26
Identities = 69/194 (35%), Positives = 105/194 (54%), Gaps = 9/194 (4%)
Frame = +1
Query: 19 KSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYE 198
K + + WD +P+GR+GDS +P+YG + Y ++ I +W P +S +DI +
Sbjct: 379 KGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPSLKIHSPQEAIAKWGTP-ESTKDISK 437
Query: 199 RFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVG 378
F + GK+ PW + L ET +I E L ++N KG+ ++ SQP+VNG +S G
Sbjct: 438 VFLNYLSGKINILPWVDAP-LSAETALIQEELFELNDKGWFSLASQPSVNGARSSDKIFG 496
Query: 379 WGGPGGYVYQKAYLEFFCSKE----KLDALVEKTKDRPFLTYMAVNKEGVWKSNV----- 531
WG G+V+QK+++E F KE KL ++ D +TY A + G +SN+
Sbjct: 497 WGPSNGFVFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDITYYAGDSSGKIQSNLPVGPD 556
Query: 532 GQTDVNAVTWGVFP 573
NAVTWGVFP
Sbjct: 557 SHNSKNAVTWGVFP 570
[151][TOP]
>UniRef100_C5DIA7 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5DIA7_LACTC
Length = 660
Score = 121 bits (304), Expect = 3e-26
Identities = 68/179 (37%), Positives = 101/179 (56%), Gaps = 3/179 (1%)
Frame = +1
Query: 46 WDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGK 225
WD++ +GR+GDS +P++G + Y + KK E W P S +DI F + G
Sbjct: 414 WDEFTNGRFGDSRSPAFGEIDGYG-PSLKVSSKKAYEIWGQP-SSTDDIKTLFIRYLEGS 471
Query: 226 LRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVY 405
L PWS+L GL ET +I E L ++N +G+L++ SQPA N S GWG PGGYVY
Sbjct: 472 LEALPWSDL-GLSAETALIQEELIQLNERGYLSLASQPATNSTPSTDKIFGWGPPGGYVY 530
Query: 406 QKAYLEFFCSKEKLDALVEKTKDRPF---LTYMAVNKEGVWKSNVGQTDVNAVTWGVFP 573
QK+++E F K++ + L K K P ++Y + + +N+ + + VTWGVFP
Sbjct: 531 QKSFVEMFVHKQQWE-LEIKPKLEPLGSKVSYYVGDSAETFYTNLDSSCSSVVTWGVFP 588
[152][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri NRRL
181 RepID=A1CZX0_NEOFI
Length = 716
Score = 120 bits (301), Expect = 8e-26
Identities = 76/206 (36%), Positives = 108/206 (52%), Gaps = 25/206 (12%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEE--WAVPLKSVEDIYER 201
+ R WD +P+GRWGD+ +P++G + Y P + W P+ S EDI
Sbjct: 428 LGREATWDDFPNGRWGDARSPAFGEIDGYG---PSLHVSGAVARRIWGYPV-SREDISAL 483
Query: 202 FRLFCLGKLRTNPWSE------LDGLQPETKIINEHLEK-INTKGFLTINSQPAVNGEKS 360
FR G L PWSE GL ET++I L K I++KG+ T+ SQPAVNG +S
Sbjct: 484 FRRHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLIDSKGWWTLASQPAVNGVRS 543
Query: 361 DSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSN 528
D PT GWG PG G+V+QK ++EFFC + +++ L + A N +G ++S+
Sbjct: 544 DDPTFGWGPPGEGFVFQKPFVEFFCPSKDFQTVLKPLFAKHGHEKLAWFATNVKGEFESS 603
Query: 529 ------------VGQTDVNAVTWGVF 570
+ +VNAVTWGVF
Sbjct: 604 LPADPAHADTIEMNPNNVNAVTWGVF 629
[153][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 120 bits (300), Expect = 1e-25
Identities = 68/182 (37%), Positives = 109/182 (59%), Gaps = 6/182 (3%)
Frame = +1
Query: 46 WDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLG- 222
WD++P+GR+ D +P+YG + + + + ++EW VP+ S D+ F +
Sbjct: 380 WDEFPNGRFTDVRSPAYGEIDGWG-SGLKITAAQALKEWGVPV-STSDLSALFTAYLHSD 437
Query: 223 -KLRTNPWSELDGLQPETKIINEHLEKINTKGFL--TINSQPAVNGEKSDSPTVGWGGPG 393
K T P+ +L L PE+ +I HL +N+ T+ SQPAV+ KS+ VGWG G
Sbjct: 438 PKHLTTPFCDLP-LSPESHMILPHLLALNSANVQHWTVGSQPAVDAAKSEDEVVGWGPRG 496
Query: 394 GYVYQKAYLEFFCSKEKLDALVEKT--KDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGV 567
GYV+QKA++EFF ++++++ L EK + + +T A N++G +K+N + VNAVTWGV
Sbjct: 497 GYVFQKAFVEFFVTEDEVNRLKEKVEREGKGLITMYAANRKGDFKTNTDKDSVNAVTWGV 556
Query: 568 FP 573
FP
Sbjct: 557 FP 558
[154][TOP]
>UniRef100_A7E9M9 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7E9M9_SCLS1
Length = 663
Score = 119 bits (299), Expect = 1e-25
Identities = 73/188 (38%), Positives = 102/188 (54%), Gaps = 6/188 (3%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 207
+ R WD +P+GRWGD+ +P+YG + Y + + I+ W P S DI + F
Sbjct: 409 LGREATWDDFPNGRWGDARSPAYGEIDGYG-VSLHMSINQAIKLWGHP-SSRADITDIFI 466
Query: 208 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 387
G+L PWSE +GL ET I + L +N KG+ T+ SQPAVNG KS GWG
Sbjct: 467 RHLEGQLTAIPWSE-EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGVKSTDSIFGWGP 525
Query: 388 PGGYVYQKAYLEFFCSKEKLDALVEKTKD---RPFLTYMAVNKEGVWKSN---VGQTDVN 549
G+V+QKA++E F +AL K R +++ A N +G + S+ +G T N
Sbjct: 526 KNGFVFQKAFVELFLPTSDWEALQAKLTSPALRDTVSFYASNAKGDFISSDEAIGST--N 583
Query: 550 AVTWGVFP 573
AVTWG FP
Sbjct: 584 AVTWGAFP 591
[155][TOP]
>UniRef100_A4RH85 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RH85_MAGGR
Length = 662
Score = 119 bits (298), Expect = 2e-25
Identities = 71/205 (34%), Positives = 106/205 (51%), Gaps = 23/205 (11%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 207
+ R WD YP+GRWGD+ +P+YG + Y + + ++ W P +VED+ F
Sbjct: 389 LGREATWDDYPNGRWGDARSPAYGEIDGYG-VSLHMSGTQAVQLWGRPA-TVEDVSNIFM 446
Query: 208 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 387
G L PWSE + ET+ I + L +N++G+ T+ SQPAVNG +S+ T GWG
Sbjct: 447 RHLRGALPAIPWSE-EEFNAETETIRDTLLALNSRGWWTVASQPAVNGLRSNDRTFGWGP 505
Query: 388 PGGYVYQKAYLEFFCSKEKLDALVEK-TKDRPFLTYMAVNKEGVWKSNVGQTD------- 543
G+V+QKA++E F + AL EK ++ + + A N +G ++S+ G D
Sbjct: 506 QNGFVFQKAFVEMFLPSKDWKALREKLLSEKDVVCFYASNAKGDFESSDGGGDAPDGAPT 565
Query: 544 ---------------VNAVTWGVFP 573
NAVTWGVFP
Sbjct: 566 GNGFADEQPLPSGSSTNAVTWGVFP 590
[156][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 119 bits (297), Expect = 2e-25
Identities = 71/203 (34%), Positives = 111/203 (54%), Gaps = 14/203 (6%)
Frame = +1
Query: 7 ANRPKSY-ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSV 183
A SY + T WD++P+GR+GDS +P++G + Y + + + + W P+ S+
Sbjct: 413 ARTSSSYQVPETSTWDEFPNGRYGDSRSPAFGEMDGYG-VSLKVPPQDALRIWGHPV-SL 470
Query: 184 EDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINT----------KGFLTINS 333
DI F + K+ PW + L ET I +HL +N KG+ ++ S
Sbjct: 471 TDISRIFGFYLEEKISCIPWCDAP-LMNETLQIRDHLLTLNRLAENASQSAGKGWWSVGS 529
Query: 334 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCS---KEKLDALVEKTKDRPFLTYMAVN 504
QPAV+G S P VG+G PGG+V+QK+++E F S K++L A ++ +TY A N
Sbjct: 530 QPAVDGAPSTDPIVGFGPPGGFVFQKSFVELFVSSSDKDRLVARIDALGASAPITYFAGN 589
Query: 505 KEGVWKSNVGQTDVNAVTWGVFP 573
+G ++SN+G + N VTW VFP
Sbjct: 590 AKGDFQSNLGDEEANTVTWAVFP 612
[157][TOP]
>UniRef100_C9S8T9 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S8T9_9PEZI
Length = 670
Score = 119 bits (297), Expect = 2e-25
Identities = 72/194 (37%), Positives = 100/194 (51%), Gaps = 12/194 (6%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 207
+ R WD +P+GRWGD+ +P+YG + Y + + + W P SV DI F
Sbjct: 408 LGREATWDDFPNGRWGDARSPAYGEIDGYG-VSLHMSVTQAVRLWGHPKSSV-DISTLFI 465
Query: 208 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 387
G+L PWSE +GL PET II E L ++NT+G+ T+ SQPAVNG S T GWG
Sbjct: 466 KHIRGELSAIPWSE-EGLSPETNIIQEQLIELNTRGWWTVASQPAVNGVPSRDATFGWGP 524
Query: 388 PGGYVYQKAYLEFFCSKEKLDALVEK---TKDRPFLTYMAVNKEGVWKSN---------V 531
G+V+QKA++E F L E+ + + + A N G + ++
Sbjct: 525 SHGFVFQKAFVELFLPAADWKVLSERLTGPEVEGTVCFYACNGNGDFATSDDSGGLVRTA 584
Query: 532 GQTDVNAVTWGVFP 573
NAVTWGVFP
Sbjct: 585 VPASTNAVTWGVFP 598
[158][TOP]
>UniRef100_A2QUJ5 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QUJ5_ASPNC
Length = 699
Score = 119 bits (297), Expect = 2e-25
Identities = 78/206 (37%), Positives = 111/206 (53%), Gaps = 25/206 (12%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDY-QFMRPRAKDKKLIEEWAVPLKSVEDIYERF 204
+ R WD +P+GRWGD+ +P++G + Y + A + I W P+ EDI F
Sbjct: 410 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVSAATARRI--WGYPVTR-EDISTLF 466
Query: 205 RLFCLGKLRTNPWSE------LDGLQPETKIIN-EHLEKINTKGFLTINSQPAVNGEKSD 363
R G+L PWSE +GL ET II E L I+ KG+ T+ SQPA+NG +SD
Sbjct: 467 RRHVSGELHMVPWSEGGAEEDSNGLNAETAIIQPELLTLIDKKGWWTLASQPAINGVRSD 526
Query: 364 SPTVGWGGPG-GYVYQKAYLEFFC-SKEKLDAL--VEKTKDRPFLTYMAVNKEGVWKS-- 525
P GWG PG G+V+QK ++EFFC +K+ L L + + L + A N +G ++S
Sbjct: 527 DPVFGWGPPGEGFVFQKPFVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNVKGDFESSL 586
Query: 526 -----------NVGQTDVNAVTWGVF 570
++ +VNAVTWGVF
Sbjct: 587 PGPNTDDPDPIDINPANVNAVTWGVF 612
[159][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR2_SCHPO
Length = 641
Score = 119 bits (297), Expect = 2e-25
Identities = 66/193 (34%), Positives = 102/193 (52%), Gaps = 2/193 (1%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDY--QFMRPRAKDKKLIEEWAVPL 174
F + + R WD + +GR+GD +P+YG + Y P ++ KL W P+
Sbjct: 380 FSVSEGSGVLGRQANWDDFTNGRFGDPRSPAYGEIDGYGPTLHFPPSEALKL---WGYPV 436
Query: 175 KSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGE 354
DI F+ + + PW + + ++ ETK I ++L K+N + T+ SQPAVNG
Sbjct: 437 DE-SDITSLFQKHIMSDISAIPWID-EPVEVETKTIAKYLLKLNGNSWWTVGSQPAVNGA 494
Query: 355 KSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVG 534
S P GWG GG V+QKA++E F + + L + K D P +TY A N + + +N
Sbjct: 495 PSADPVFGWGPKGGRVFQKAFVECFVNGKDLKDFITKWHDNPQVTYYAGNNKSEFLTNAP 554
Query: 535 QTDVNAVTWGVFP 573
+ +AVTWGV+P
Sbjct: 555 KDGASAVTWGVYP 567
[160][TOP]
>UniRef100_UPI000023F2EE hypothetical protein FG07127.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023F2EE
Length = 672
Score = 118 bits (296), Expect = 3e-25
Identities = 70/195 (35%), Positives = 109/195 (55%), Gaps = 13/195 (6%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 207
+ R WD +P+GR+GD+ +P+YG + Y + + ++ W P K+ +DI + F
Sbjct: 409 LGREATWDDFPNGRFGDARSPAYGEIDGYG-VSLHMSVTQAVKLWDYP-KTRQDINDLFV 466
Query: 208 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 387
G+L PWSE + L+ E+ I HL ++N KG+ T+ SQPAVNG +S T GWG
Sbjct: 467 KHIQGELSAIPWSE-EELRAESSTIKPHLLQLNGKGWWTVASQPAVNGLRSSDATFGWGP 525
Query: 388 PGGYVYQKAYLEFFCSK---EKLDALVEKTKDRPFLTYMAVNKEGVW-KSNVG------- 534
P G+V+QK+++EFF E L A + ++ + ++ + A N G + S++G
Sbjct: 526 PNGFVFQKSFVEFFIPANEWEILKAKLVSSELQDYVCFYASNARGDYVSSDIGGHVDGST 585
Query: 535 --QTDVNAVTWGVFP 573
NAVTWGVFP
Sbjct: 586 EASPSTNAVTWGVFP 600
[161][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 118 bits (296), Expect = 3e-25
Identities = 76/206 (36%), Positives = 107/206 (51%), Gaps = 25/206 (12%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEE--WAVPLKSVEDIYER 201
+ R WD +P+GRWGD+ +P++G + Y P + W P+ S EDI
Sbjct: 401 LGREATWDDFPNGRWGDARSPAFGEIDGYG---PSLHVSGAVARRIWGYPV-SREDISAL 456
Query: 202 FRLFCLGKLRTNPWSE------LDGLQPETKIINEHLEK-INTKGFLTINSQPAVNGEKS 360
FR G L PWSE GL ET++I L K I+ KG+ T+ SQPAVNG +S
Sbjct: 457 FRRHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRS 516
Query: 361 DSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSN 528
D PT GWG PG G+V+QK ++EFFC + +++ L + A N +G ++S+
Sbjct: 517 DDPTFGWGPPGEGFVFQKPFVEFFCPSKDFRTVLKPLFAKHGHEKLAWFATNVKGEFESS 576
Query: 529 ------------VGQTDVNAVTWGVF 570
+ +VNAVTWGVF
Sbjct: 577 LPADPAHADTIEMNPNNVNAVTWGVF 602
[162][TOP]
>UniRef100_Q7S2B6 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S2B6_NEUCR
Length = 681
Score = 118 bits (295), Expect = 4e-25
Identities = 71/207 (34%), Positives = 105/207 (50%), Gaps = 25/207 (12%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 207
+ R WD +P+GRWGD+ +P+YG + Y + + ++ W P K+ EDI + F
Sbjct: 406 LGREATWDDFPNGRWGDARSPAYGQIDGYG-VSLHVTVPQALQLWGSP-KTTEDINKIFI 463
Query: 208 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 387
G+L PWSE +G ET+ I ++L ++N++G+ ++ SQPAVNG +SD T GWG
Sbjct: 464 RHLKGELSAIPWSE-EGFNDETEAIRDNLIELNSRGWWSLASQPAVNGLRSDDGTFGWGP 522
Query: 388 PGGYVYQKAYLEFFCSKEKLDALVEKTKDRP-----------------------FLTYMA 498
G+V+QKA++EFF L K K F MA
Sbjct: 523 ENGFVFQKAFVEFFIPSADWRVLEAKLKQPDMKDTVCFFATNAAGDFVSTDTINFRARMA 582
Query: 499 VNKEGVWKSN--VGQTDVNAVTWGVFP 573
EG +++ + NAVTWGVFP
Sbjct: 583 AEAEGTAEADHRPHEPSTNAVTWGVFP 609
[163][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 118 bits (295), Expect = 4e-25
Identities = 76/206 (36%), Positives = 107/206 (51%), Gaps = 25/206 (12%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEE--WAVPLKSVEDIYER 201
+ R WD +P+GRWGD+ +P++G + Y P + W P+ S EDI
Sbjct: 401 LGREATWDDFPNGRWGDARSPAFGEIDGYG---PSLHVSGAVARRIWGYPV-SREDISAL 456
Query: 202 FRLFCLGKLRTNPWSE------LDGLQPETKIINEHLEK-INTKGFLTINSQPAVNGEKS 360
FR G L PWSE GL ET++I L K I+ KG+ T+ SQPAVNG +S
Sbjct: 457 FRHHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRS 516
Query: 361 DSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSN 528
D PT GWG PG G+V+QK ++EFFC + +++ L + A N +G ++S+
Sbjct: 517 DDPTFGWGPPGEGFVFQKPFVEFFCPSKDFRTVLKPLFAKHGHEKLAWFATNVKGEFESS 576
Query: 529 ------------VGQTDVNAVTWGVF 570
+ +VNAVTWGVF
Sbjct: 577 LPADPAHADTIEMNPNNVNAVTWGVF 602
[164][TOP]
>UniRef100_A1C4Z1 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C4Z1_ASPCL
Length = 690
Score = 118 bits (295), Expect = 4e-25
Identities = 74/206 (35%), Positives = 109/206 (52%), Gaps = 25/206 (12%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEE--WAVPLKSVEDIYER 201
+ R WD +P+GRWGD+ +P++G + Y P + W P+ S +DI
Sbjct: 402 LGREATWDDFPNGRWGDARSPAFGEIDGYG---PSLHVSPTVARRVWGYPV-SRDDISTL 457
Query: 202 FRLFCLGKLRTNPWSE------LDGLQPETKIINEHLEK-INTKGFLTINSQPAVNGEKS 360
FR G+L PWSE GL ET++I L K I+ KG+ T+ SQPAVNG +S
Sbjct: 458 FRRHVSGELYIVPWSEGGAEENTSGLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRS 517
Query: 361 DSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSN 528
D+ T GWG PG G+V+QK ++EFFC + + +++ L + A N +G ++S+
Sbjct: 518 DNSTFGWGPPGEGFVFQKPFVEFFCPSKDFETVLKPLFANHGHEKLAWFATNAKGEFQSS 577
Query: 529 V------------GQTDVNAVTWGVF 570
+ +VNAVTWGVF
Sbjct: 578 LPAETADSDALEPNPDNVNAVTWGVF 603
[165][TOP]
>UniRef100_C7YTQ6 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YTQ6_NECH7
Length = 674
Score = 117 bits (294), Expect = 5e-25
Identities = 71/195 (36%), Positives = 103/195 (52%), Gaps = 13/195 (6%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 207
+ R WD +P+GR+GD+ +P+YG + Y + + ++ W P K+ +DI + F
Sbjct: 411 LGREATWDDFPNGRFGDARSPAYGEIDGYG-VSLHMSITQAVKLWGHP-KTRQDINDLFV 468
Query: 208 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 387
G+L PWSE + L E+ I HL ++N KG+ T+ SQPAVNG +S T GWG
Sbjct: 469 KHIQGQLSAIPWSE-EELLAESSTIQPHLLRLNQKGWWTVASQPAVNGLRSSDGTFGWGP 527
Query: 388 PGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF---LTYMAVNKEG--VWKSNVGQTD--- 543
P G+V+QK+++EFF + L EK + + A N +G V G D
Sbjct: 528 PNGFVFQKSFVEFFIPSSEWSVLKEKLNSSELCDSVCFYAGNAKGDFVSSDKGGHVDGSS 587
Query: 544 -----VNAVTWGVFP 573
NAVTWGVFP
Sbjct: 588 GAGPSTNAVTWGVFP 602
[166][TOP]
>UniRef100_C8V780 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5AU15] n=2 Tax=Emericella
nidulans RepID=C8V780_EMENI
Length = 684
Score = 117 bits (293), Expect = 6e-25
Identities = 78/208 (37%), Positives = 108/208 (51%), Gaps = 27/208 (12%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQ---FMRPRAKDKKLIEEWAVPLKSVEDIYE 198
+ R WD +P+GRWGD+ +P++G + Y + P + W P+ S +DI +
Sbjct: 397 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVAPSVAHRI----WGYPV-STDDISK 451
Query: 199 RFRLFCLGKLRTNPWSE------LDGLQPETKIIN-EHLEKINTKGFLTINSQPAVNGEK 357
FR G L PWSE GL ET+ I E L I+ KG+ T+ SQPAVNG +
Sbjct: 452 LFRRHVSGDLHMVPWSEGGAEENTSGLNAETETIRPELLALIDKKGWWTLASQPAVNGVR 511
Query: 358 SDSPTVGWGGPG-GYVYQKAYLEFFCS----KEKLDALVEKTKDRPFLTYMAVNKEGVWK 522
SD P GWG PG G+V+QK ++EFFC K L L++K L + A N G ++
Sbjct: 512 SDDPIFGWGPPGEGFVFQKPFVEFFCPASDFKTTLKPLLQK-HGHEKLAWFATNAAGDFE 570
Query: 523 SN------------VGQTDVNAVTWGVF 570
S+ + +VNAVTWGVF
Sbjct: 571 SSLPAETSDTEPVEMNPNNVNAVTWGVF 598
[167][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NEV2_COPC7
Length = 617
Score = 117 bits (293), Expect = 6e-25
Identities = 63/179 (35%), Positives = 101/179 (56%), Gaps = 3/179 (1%)
Frame = +1
Query: 46 WDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDK-KLIEEWAVPLKSVEDIYERFRLFCLG 222
WD +P+GR+GD +P++G + + + +++W P K+ +D+ F
Sbjct: 363 WDDFPNGRFGDFKSPAFGNQDPWGGPGGLGISRAEALQQWGYP-KTFDDLTRIFLAHLHS 421
Query: 223 KLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYV 402
++ P+S + L PE+ I HLE++ +G+ T+ SQPAV+G S T GWG GYV
Sbjct: 422 EIPITPFSPTE-LCPESITILPHLERLTKRGWWTVGSQPAVDGISSSDETFGWGPRAGYV 480
Query: 403 YQKAYLEFFCSKEKLDALVEKTKDR--PFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFP 573
+QK ++EFFC ++A+ ++ K R ++ Y N G +SNV + NAVTWGVFP
Sbjct: 481 FQKGFVEFFCDFHDVEAIEQRIKQRGAGWVHYFMANNNGECRSNVPEDGRNAVTWGVFP 539
[168][TOP]
>UniRef100_A7QB32 Chromosome chr5 scaffold_72, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7QB32_VITVI
Length = 170
Score = 117 bits (292), Expect = 8e-25
Identities = 67/143 (46%), Positives = 84/143 (58%), Gaps = 1/143 (0%)
Frame = +1
Query: 79 SGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDG 258
S NPSYGAL DYQFMRP A DKKL EEW VPLKSVEDI +RF FC GKL+ PW E +G
Sbjct: 3 SCNPSYGALIDYQFMRPHACDKKLQEEWVVPLKSVEDIQKRFMKFCRGKLKNGPWKEFEG 62
Query: 259 LQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGY-VYQKAYLEFFCS 435
LQP+TKII+E + IN KG P + WGG G ++ K ++ + S
Sbjct: 63 LQPDTKIIDEPIGNINLKGKWGKIGLP-----------IWWGGVGQVGMFTKRLMQSYPS 111
Query: 436 KEKLDALVEKTKDRPFLTYMAVN 504
+ L+E+ + FL + N
Sbjct: 112 R----ILLEEVQSSYFLVSLVDN 130
[169][TOP]
>UniRef100_C5M548 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M548_CANTT
Length = 633
Score = 115 bits (289), Expect = 2e-24
Identities = 65/191 (34%), Positives = 101/191 (52%), Gaps = 5/191 (2%)
Frame = +1
Query: 19 KSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYE 198
K + + WD +P+GR+GDS +P+YG + Y + +W P ++ +D+ +
Sbjct: 373 KGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPTLKIHSPAEAEIKWGSP-ETTKDLAQ 431
Query: 199 RFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVG 378
F + GK+ PW++ L PET +I E L ++N KG+ ++ SQPA N KS G
Sbjct: 432 IFIDYLSGKIDVIPWAD-QALSPETALIQEELFQLNEKGWFSVASQPAANACKSTDNIFG 490
Query: 379 WGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVG-----QTD 543
WG G VYQKA++E F K+ + L + +TY A +K ++ V +
Sbjct: 491 WGPRNGVVYQKAFVELFMPKDDWNKLKPLVEASDSITYYAADKTNKIEAKVPAGHDIKLT 550
Query: 544 VNAVTWGVFPA 576
NAVTWGVFP+
Sbjct: 551 KNAVTWGVFPS 561
[170][TOP]
>UniRef100_C4R2L4 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2L4_PICPG
Length = 596
Score = 115 bits (289), Expect = 2e-24
Identities = 63/178 (35%), Positives = 100/178 (56%), Gaps = 2/178 (1%)
Frame = +1
Query: 46 WDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGK 225
WD +P+GR+GDS +P+YG + Y + + + W P+ ++DI + F + +
Sbjct: 349 WDDFPNGRYGDSRSPAYGEIDGYG-PSLKVSSSRAYKLWGYPV-DLDDITKIFIAYLSNR 406
Query: 226 LRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVY 405
+ PWSEL GL PET +I E L ++N K TI+SQP+ NG KS GWG GYVY
Sbjct: 407 ITALPWSEL-GLNPETGLIQEELIQLNEKHMFTISSQPSANGVKSTDKLFGWGPSEGYVY 465
Query: 406 QKAYLEFFCSKEKL-DALVEKTKDRPFLTYMAVNKEGVWKSNVG-QTDVNAVTWGVFP 573
QKA++E F +K++ + ++ + +T+ + + +N+ N+VTWG FP
Sbjct: 466 QKAFVEVFINKKQWNEEILPNLQGHKSVTWYLGDCNNAFDTNIKIPLSSNSVTWGCFP 523
[171][TOP]
>UniRef100_C1H0K0 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1H0K0_PARBA
Length = 713
Score = 115 bits (289), Expect = 2e-24
Identities = 75/212 (35%), Positives = 109/212 (51%), Gaps = 31/212 (14%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDY-QFMRPRAKDKKLIEEWAVPLKSVEDIYERF 204
+ R WD +P+GRWGD+ +P++G + Y + A + + W P S EDI + F
Sbjct: 409 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVNANVARQL--WGYPT-SKEDINKLF 465
Query: 205 RLFCLGKLRTNPWSE------LDGLQPETKIINEHL-EKINTKGFLTINSQPAVNGEKSD 363
G+L PWSE GL ET I E L + I+ +G+ T+ SQPAVNG +SD
Sbjct: 466 HCHVSGELHIVPWSEGGSAEDSGGLNAETATIREELLQLIDGRGWWTLASQPAVNGVRSD 525
Query: 364 SPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSN- 528
P GWG G G+V+QKA++EFFCS + + +++ K + L++ A N G ++S+
Sbjct: 526 HPIFGWGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQSSS 585
Query: 529 ------------------VGQTDVNAVTWGVF 570
VNAVTWGVF
Sbjct: 586 SFTGITGLDDAVPDYNGAASSNGVNAVTWGVF 617
[172][TOP]
>UniRef100_C1GJU2 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1GJU2_PARBD
Length = 712
Score = 115 bits (288), Expect = 2e-24
Identities = 75/212 (35%), Positives = 109/212 (51%), Gaps = 31/212 (14%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDY-QFMRPRAKDKKLIEEWAVPLKSVEDIYERF 204
+ R WD +P+GRWGD+ +P++G + Y + A + + W P S EDI + F
Sbjct: 409 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVNANVARQL--WGYPT-SREDINKLF 465
Query: 205 RLFCLGKLRTNPWSE------LDGLQPETKIINEHL-EKINTKGFLTINSQPAVNGEKSD 363
G+L PWSE GL ET I E L + I+ +G+ T+ SQPAVNG +SD
Sbjct: 466 HCHVSGELHIVPWSEGGSAEDSGGLNAETATIREELLQLIDGRGWWTLASQPAVNGVRSD 525
Query: 364 SPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSN- 528
P GWG G G+V+QKA++EFFCS + + +++ K + L++ A N G ++S+
Sbjct: 526 HPIFGWGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQSSS 585
Query: 529 ------------------VGQTDVNAVTWGVF 570
VNAVTWGVF
Sbjct: 586 SFTGTTGLDDAVPDYNGAASSNGVNAVTWGVF 617
[173][TOP]
>UniRef100_C0S8C4 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0S8C4_PARBP
Length = 712
Score = 115 bits (288), Expect = 2e-24
Identities = 75/212 (35%), Positives = 109/212 (51%), Gaps = 31/212 (14%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDY-QFMRPRAKDKKLIEEWAVPLKSVEDIYERF 204
+ R WD +P+GRWGD+ +P++G + Y + A + + W P S EDI + F
Sbjct: 409 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVNANVARQL--WGYPT-SREDINKLF 465
Query: 205 RLFCLGKLRTNPWSE------LDGLQPETKIINEHL-EKINTKGFLTINSQPAVNGEKSD 363
G+L PWSE GL ET I E L + I+ +G+ T+ SQPAVNG +SD
Sbjct: 466 HCHVSGELHIVPWSEGGSAEDSGGLNAETATIREELLQLIDGRGWWTLASQPAVNGVRSD 525
Query: 364 SPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSN- 528
P GWG G G+V+QKA++EFFCS + + +++ K + L++ A N G ++S+
Sbjct: 526 HPIFGWGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQSSS 585
Query: 529 ------------------VGQTDVNAVTWGVF 570
VNAVTWGVF
Sbjct: 586 SFTGTTGLDDAVPDYSGAASSNGVNAVTWGVF 617
[174][TOP]
>UniRef100_A6RQJ7 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6RQJ7_BOTFB
Length = 663
Score = 114 bits (285), Expect = 5e-24
Identities = 72/188 (38%), Positives = 99/188 (52%), Gaps = 6/188 (3%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 207
+ R WD +P+GRWGD+ +P+YG + Y + + I+ W P S DI + F
Sbjct: 409 LGREATWDDFPNGRWGDARSPAYGEIDGYG-VSLHMSINQAIKLWGHP-SSRADITDIFI 466
Query: 208 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 387
G+L PWSE +GL ET I + L +N KG+ T+ SQPAVNG KS GWG
Sbjct: 467 RHLEGQLTAIPWSE-EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGLKSSDSIFGWGP 525
Query: 388 PGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF---LTYMAVNKEGVWKSN---VGQTDVN 549
G+V+QKA++E F L K +++ A N +G + S+ VG T N
Sbjct: 526 KNGFVFQKAFVELFIPVADWKTLHAKLTSPDLCDTVSFYASNAKGDFISSDEAVGST--N 583
Query: 550 AVTWGVFP 573
AVTWG FP
Sbjct: 584 AVTWGAFP 591
[175][TOP]
>UniRef100_A5DZ35 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DZ35_LODEL
Length = 622
Score = 114 bits (285), Expect = 5e-24
Identities = 65/193 (33%), Positives = 104/193 (53%), Gaps = 5/193 (2%)
Frame = +1
Query: 10 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 189
+R K + + WD +P+GR+GDS +P+YG + Y + I +W P ++++
Sbjct: 362 SRGKGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPSLKIHNASEAIAKWGSPT-NIKE 420
Query: 190 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 369
+ + F + GK+ PW++ L PET +I E L ++N KG+ ++ SQPAVNG +S+
Sbjct: 421 LGQVFVDYLSGKIDVVPWADTS-LSPETALIQEELFELNQKGWFSVASQPAVNGCRSNDN 479
Query: 370 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEG-----VWKSNVG 534
GWG G VYQK+++E F + L + D TY +K G ++ +
Sbjct: 480 VFGWGPGNGVVYQKSFVELFIPAKDWKELKPRLDDA--TTYYVGDKSGRIELSLFTNEST 537
Query: 535 QTDVNAVTWGVFP 573
+ NAVTWGVFP
Sbjct: 538 RHLKNAVTWGVFP 550
[176][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 114 bits (284), Expect = 7e-24
Identities = 65/180 (36%), Positives = 103/180 (57%), Gaps = 4/180 (2%)
Frame = +1
Query: 46 WDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGK 225
WD +P+GR+GD +P++G + D ++ +W P KS++D+ + F K
Sbjct: 351 WDDFPNGRFGDFKSPAFGNQDLWGGSGISGSD--VLAQWNNP-KSLDDLTQIFLGHLHAK 407
Query: 226 LRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVY 405
+ T P+S L E+ +I HLE++ + + T+ SQPAV+G S VGWG GGYV+
Sbjct: 408 ILTTPFSPTP-LSSESLMILPHLERLTRRSWWTVGSQPAVDGVSSGDKVVGWGPRGGYVF 466
Query: 406 QKAYLEFFCSKEKLDALVEKTK--DRPFLTYMAVN--KEGVWKSNVGQTDVNAVTWGVFP 573
QK ++EFFC ++ +D + + + ++ Y A N +G +SNV + NAVTWGVFP
Sbjct: 467 QKGFVEFFCEEKDMDVIERRVERNGHGWVHYFAGNYKADGECRSNVPEGGRNAVTWGVFP 526
[177][TOP]
>UniRef100_Q0CE17 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CE17_ASPTN
Length = 696
Score = 113 bits (283), Expect = 9e-24
Identities = 76/207 (36%), Positives = 109/207 (52%), Gaps = 26/207 (12%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQ---FMRPRAKDKKLIEEWAVPLKSVEDIYE 198
+ R WD +P+GRWGD+ +P++G + Y + P + W P+ +DI
Sbjct: 409 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTPSVAHRI----WGYPVTR-DDINT 463
Query: 199 RFRLFCLGKLRTNPWSE------LDGLQPETKIIN-EHLEKINTKGFLTINSQPAVNGEK 357
FR G+L PWSE GL PET+ I E L+ I+ KG+ T+ SQPAVNG +
Sbjct: 464 LFRRHVSGELHMVPWSEGGAEEGSGGLNPETETIRPELLQLIDGKGWWTLASQPAVNGVR 523
Query: 358 SDSPTVGWGGP-GGYVYQKAYLEFFC-SKEKLDAL--VEKTKDRPFLTYMAVNKEGVWKS 525
SD P GWG P G+V+QK ++EFFC +K+ AL + + L + A N G ++S
Sbjct: 524 SDDPIFGWGPPREGFVFQKPFVEFFCPTKDYQTALKPMLQKHGHEKLAWFATNANGDFES 583
Query: 526 N------------VGQTDVNAVTWGVF 570
+ + +VNAVTWGVF
Sbjct: 584 SLPAQTSDADPIEMNPNNVNAVTWGVF 610
[178][TOP]
>UniRef100_Q2UA39 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus oryzae
RepID=Q2UA39_ASPOR
Length = 690
Score = 112 bits (281), Expect = 2e-23
Identities = 72/206 (34%), Positives = 108/206 (52%), Gaps = 25/206 (12%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDY--QFMRPRAKDKKLIEEWAVPLKSVEDIYER 201
+ R WD +P+GRWGD+ +P++G + Y P A ++ W P+ S EDI
Sbjct: 401 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVPPAVAHRI---WGFPV-SHEDISAL 456
Query: 202 FRLFCLGKLRTNPWSE------LDGLQPETKIIN-EHLEKINTKGFLTINSQPAVNGEKS 360
F G+L PWSE GL ET++I E L+ I+ G+ T+ SQPAVNG +S
Sbjct: 457 FHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPELLQLIDGNGWWTLASQPAVNGVRS 516
Query: 361 DSPTVGWGGP-GGYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSN 528
D P GWG P G+V+QK ++EFFC + ++++ + L + A N +G ++S+
Sbjct: 517 DDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLLQKHGHEKLAWFAANVKGDFESS 576
Query: 529 ------------VGQTDVNAVTWGVF 570
+ +VN VTWGVF
Sbjct: 577 LPAQTSDADPIEMNPNNVNCVTWGVF 602
[179][TOP]
>UniRef100_B8NQE8 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus flavus
NRRL3357 RepID=B8NQE8_ASPFN
Length = 738
Score = 112 bits (281), Expect = 2e-23
Identities = 72/206 (34%), Positives = 108/206 (52%), Gaps = 25/206 (12%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDY--QFMRPRAKDKKLIEEWAVPLKSVEDIYER 201
+ R WD +P+GRWGD+ +P++G + Y P A ++ W P+ S EDI
Sbjct: 449 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVPPAVAHRI---WGFPV-SHEDISAL 504
Query: 202 FRLFCLGKLRTNPWSE------LDGLQPETKIIN-EHLEKINTKGFLTINSQPAVNGEKS 360
F G+L PWSE GL ET++I E L+ I+ G+ T+ SQPAVNG +S
Sbjct: 505 FHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPELLQLIDGNGWWTLASQPAVNGVRS 564
Query: 361 DSPTVGWGGP-GGYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSN 528
D P GWG P G+V+QK ++EFFC + ++++ + L + A N +G ++S+
Sbjct: 565 DDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLLQKHGHEKLAWFAANVKGDFESS 624
Query: 529 ------------VGQTDVNAVTWGVF 570
+ +VN VTWGVF
Sbjct: 625 LPAQTSDADPIEMNPNNVNCVTWGVF 650
[180][TOP]
>UniRef100_Q1DT03 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DT03_COCIM
Length = 711
Score = 112 bits (280), Expect = 2e-23
Identities = 78/218 (35%), Positives = 107/218 (49%), Gaps = 37/218 (16%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDY-QFMRPRAKDKKLIEEWAVPLKSVEDIYERF 204
+ R WD +P+GRWGD+ +P++G + Y + A + + W P EDI F
Sbjct: 407 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTANVARRL--WGYPTTR-EDINNIF 463
Query: 205 RLFCLGKLRTNPWSE------LDGLQPETKIINEHL-EKINTKGFLTINSQPAVNGEKSD 363
R G L PWSE GL PET I +L I +G+ TI SQPAV+G +SD
Sbjct: 464 RQHVSGGLHAVPWSEGGAAEETGGLSPETITIRPYLLSLIEKRGWWTIASQPAVSGVRSD 523
Query: 364 SPTVGWGGPG-GYVYQKAYLEFFCSKE----KLDALVEKTKDRPFLTYMAVNKEGVWKSN 528
P GWG PG G+V+QKA++EFFCSK+ L L+++ F + A N G ++S+
Sbjct: 524 HPIFGWGPPGEGFVFQKAFVEFFCSKDDYRSHLKPLLQRYGHDEF-AWFATNAAGDFESS 582
Query: 529 VGQT------------------------DVNAVTWGVF 570
+ VNAVTWGVF
Sbjct: 583 TSSSIPVPTGPVDAVFDDMDSFPSSNSGGVNAVTWGVF 620
[181][TOP]
>UniRef100_C4Y9Q4 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y9Q4_CLAL4
Length = 601
Score = 112 bits (280), Expect = 2e-23
Identities = 62/182 (34%), Positives = 102/182 (56%), Gaps = 5/182 (2%)
Frame = +1
Query: 46 WDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGK 225
WD +P+GR+GD+ +P+YG + Y + + + + W P +SV D+ F + K
Sbjct: 352 WDDFPNGRFGDASSPAYGEIDGYG-PSLKLEPPEAVAVWGTP-QSVADVSRVFIDYLSAK 409
Query: 226 LRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVY 405
+ + PW + L PET +I E L ++N++G T+ SQPAV+ S +GWG G ++
Sbjct: 410 ISSLPWVSTE-LSPETALIQEQLFELNSRGLFTLASQPAVDSCPSSDSILGWGPRNGRIF 468
Query: 406 QKAYLEFFCSK---EKLDALVEKTKDRPFLTYMAVNKEGVWKSNV--GQTDVNAVTWGVF 570
QK+++EFF K E+L L++K +TY N +G +N+ + A+TWGVF
Sbjct: 469 QKSFVEFFVPKTEWERLLRLMDKDISDKTITYFCGNSKGEITTNMPHKSSQRTAITWGVF 528
Query: 571 PA 576
P+
Sbjct: 529 PS 530
[182][TOP]
>UniRef100_C4JM22 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii 1704
RepID=C4JM22_UNCRE
Length = 709
Score = 112 bits (280), Expect = 2e-23
Identities = 77/218 (35%), Positives = 110/218 (50%), Gaps = 37/218 (16%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDY-QFMRPRAKDKKLIEEWAVPLKSVEDIYERF 204
+ R WD +P+GRWGD+ +P++G + Y + A + + W P S EDI + F
Sbjct: 405 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTANVARRL--WGFPT-SREDINQIF 461
Query: 205 RLFCLGKLRTNPWSE------LDGLQPETKIINEHL-EKINTKGFLTINSQPAVNGEKSD 363
R G L PWSE GL PET I +L + I+ +G+ T+ SQPAVNG +SD
Sbjct: 462 RRHVSGALHAVPWSEGGAAEESGGLNPETATIRPYLLDLIDKRGWWTLASQPAVNGVRSD 521
Query: 364 SPTVGWGGPG-GYVYQKAYLEFFCS----KEKLDALVEKTKDRPFLTYMAVNKEGVWKSN 528
T GWG PG G+V+QKA++EFFCS + L L+++ F + A N G ++++
Sbjct: 522 DTTFGWGPPGEGFVFQKAFVEFFCSSNDYRSYLKPLLQRYGHDEF-AWFATNAAGDFEAS 580
Query: 529 VGQT------------------------DVNAVTWGVF 570
+ VNAVTWGVF
Sbjct: 581 TPPSAHSPTEPVDAGFEDPSSPAASNPGGVNAVTWGVF 618
[183][TOP]
>UniRef100_Q3EAG8 Methylenetetrahydrofolate reductase n=1 Tax=Arabidopsis thaliana
RepID=Q3EAG8_ARATH
Length = 407
Score = 112 bits (279), Expect = 3e-23
Identities = 46/67 (68%), Positives = 56/67 (83%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FWANRPKSYISRT GW+ +PHGRWGDS + +Y L+DYQF RP+ +DKKL +EW VPLKS
Sbjct: 331 FWANRPKSYISRTKGWNDFPHGRWGDSHSAAYSTLSDYQFARPKGRDKKLQQEWVVPLKS 390
Query: 181 VEDIYER 201
+ED+ ER
Sbjct: 391 IEDVQER 397
[184][TOP]
>UniRef100_C5P4Q4 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5P4Q4_COCP7
Length = 711
Score = 111 bits (278), Expect = 4e-23
Identities = 77/218 (35%), Positives = 107/218 (49%), Gaps = 37/218 (16%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDY-QFMRPRAKDKKLIEEWAVPLKSVEDIYERF 204
+ R WD +P+GRWGD+ +P++G + Y + A + + W P EDI F
Sbjct: 407 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTANVARRL--WGYPTTR-EDINNIF 463
Query: 205 RLFCLGKLRTNPWSE------LDGLQPETKIINEHL-EKINTKGFLTINSQPAVNGEKSD 363
R G L PWSE GL PET I +L I +G+ T+ SQPAV+G +SD
Sbjct: 464 RQHVSGGLHAVPWSEGGAAEETGGLSPETITIRPYLLSLIEKRGWWTLASQPAVSGVRSD 523
Query: 364 SPTVGWGGPG-GYVYQKAYLEFFCSKE----KLDALVEKTKDRPFLTYMAVNKEGVWKSN 528
P GWG PG G+V+QKA++EFFCSK+ L L+++ F + A N G ++S+
Sbjct: 524 HPIFGWGPPGEGFVFQKAFVEFFCSKDDYRSHLKPLLQRYGHDEF-AWFATNAAGDFESS 582
Query: 529 VGQT------------------------DVNAVTWGVF 570
+ VNAVTWGVF
Sbjct: 583 TSSSIPVPTGPVDAVFDDMDSFPSSNSGGVNAVTWGVF 620
[185][TOP]
>UniRef100_C5GI01 Methylenetetrahydrofolate reductase n=2 Tax=Ajellomyces dermatitidis
RepID=C5GI01_AJEDR
Length = 713
Score = 111 bits (278), Expect = 4e-23
Identities = 76/217 (35%), Positives = 107/217 (49%), Gaps = 36/217 (16%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDY--QFMRPRAKDKKLIEEWAVPLKSVEDIYER 201
+ R WD +P+GRWGD+ +P++G + Y A ++L W P EDI
Sbjct: 406 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTPAVARRL---WGYPTTK-EDINTI 461
Query: 202 FRLFCLGKLRTNPWSE-----LDGLQPETKII-NEHLEKINTKGFLTINSQPAVNGEKSD 363
F+ G L PWSE GL ET I +E L+ IN +G+ T+ SQPAVNG ++D
Sbjct: 462 FQRHVSGDLHIVPWSEGGTQDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRND 521
Query: 364 SPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSN- 528
P GWG G G+V+QKA++EFFC+ L +++ + L + A N G ++S+
Sbjct: 522 HPIFGWGPRGEGFVFQKAFVEFFCTAHDLKTILKPIFENHGHDELAWFATNAAGDFESSS 581
Query: 529 -----------------------VGQTDVNAVTWGVF 570
G T VNAVTWGVF
Sbjct: 582 PPTDDSANDYSGPVDVYLDSNATAGGTGVNAVTWGVF 618
[186][TOP]
>UniRef100_Q9SE60-2 Isoform 2 of Methylenetetrahydrofolate reductase 1 n=1
Tax=Arabidopsis thaliana RepID=Q9SE60-2
Length = 421
Score = 110 bits (274), Expect = 1e-22
Identities = 45/66 (68%), Positives = 55/66 (83%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FWANRPKSYISRT GW+ +PHGRWGDS + +Y L+DYQF RP+ +DKKL +EW VPLKS
Sbjct: 331 FWANRPKSYISRTKGWNDFPHGRWGDSHSAAYSTLSDYQFARPKGRDKKLQQEWVVPLKS 390
Query: 181 VEDIYE 198
+ED+ E
Sbjct: 391 IEDVQE 396
[187][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 108 bits (271), Expect = 2e-22
Identities = 77/218 (35%), Positives = 110/218 (50%), Gaps = 37/218 (16%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDY-QFMRPRAKDKKLIEEWAVPLKSVEDIYERF 204
+ R WD +P+GRWGD+ +P++G + Y + A+ + + W P S EDI F
Sbjct: 367 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTARVARKL--WGTP-TSREDISNIF 423
Query: 205 RLFCLGKLRTNPWS-----ELDGLQPETKII-NEHLEKINTKGFLTINSQPAVNGEKSDS 366
R G+L PWS E GL PET I E L+ + +G+ T+ SQP+VNG ++D
Sbjct: 424 RRLLSGELHAVPWSEGGAGEEGGLNPETATIRTELLKLVEGRGWWTLASQPSVNGVRNDH 483
Query: 367 PTVGWGGPG-GYVYQKAYLEFFCSKE----KLDALVEKTKDRPFLTYMAVNKEGVWKSNV 531
P GWG G G+V+QKA++EFFC + KL L+ F + A+N +G ++S+
Sbjct: 484 PIFGWGPRGEGFVFQKAFVEFFCPGDDFHSKLKPLLNSYGHDEF-AWFAMNAKGDFQSST 542
Query: 532 G----------------QTD---------VNAVTWGVF 570
TD VNAVTWGVF
Sbjct: 543 SPEPPASPPTDSTEPLFDTDPLTDMDNGSVNAVTWGVF 580
[188][TOP]
>UniRef100_C0NTN2 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NTN2_AJECG
Length = 713
Score = 107 bits (266), Expect = 9e-22
Identities = 72/217 (33%), Positives = 106/217 (48%), Gaps = 36/217 (16%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDY--QFMRPRAKDKKLIEEWAVPLKSVEDIYER 201
+ R WD +P+GRWGD+ +P++G + Y A ++L W P +DI
Sbjct: 406 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVNAAVARRL---WGYPTTK-QDINNI 461
Query: 202 FRLFCLGKLRTNPWSE-----LDGLQPETKII-NEHLEKINTKGFLTINSQPAVNGEKSD 363
F+ G+L PWSE GL ET I +E L+ IN +G+ T+ SQPAVNG ++D
Sbjct: 462 FQRHVSGELHLVPWSEGGAQDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRND 521
Query: 364 SPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKS-- 525
P GWG G G+V+QKA++EFFC +++++ ++ + A N G + S
Sbjct: 522 HPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNAAGDFMSSS 581
Query: 526 ----------------------NVGQTDVNAVTWGVF 570
+ G T V AVTWGVF
Sbjct: 582 PATDATTEDSSGPVDVFLDSNVSPGNTGVTAVTWGVF 618
[189][TOP]
>UniRef100_B6HK87 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6HK87_PENCW
Length = 691
Score = 107 bits (266), Expect = 9e-22
Identities = 71/207 (34%), Positives = 108/207 (52%), Gaps = 26/207 (12%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDY-QFMRPRAKDKKLIEEWAVPLKSVEDIYERF 204
+ R WD +P+GRWGD+ +P++G + Y + A + + W P+ S +D+ F
Sbjct: 400 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTANTARRL--WGHPVDS-KDMSAIF 456
Query: 205 RLFCLGKLRTNPWSE------LDGLQPETKIIN-EHLEKINTKGFLTINSQPAVNGEKSD 363
R G+L PWSE +GL ET++I E L+ I+ +G+ T+ SQPAVNG +D
Sbjct: 457 RRHVSGELHMVPWSEGGAEEDGEGLNAETELIRPELLKLIDGRGWWTLASQPAVNGVHND 516
Query: 364 SPTVGWGGP-GGYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSNV 531
P GWG G+V+QK ++EFFCS +++ LT+ A N +G ++S++
Sbjct: 517 HPIFGWGPQREGFVFQKPFVEFFCSSNDYTNILKPLFAKHGHDKLTWFATNVKGDFESSL 576
Query: 532 --------------GQTDVNAVTWGVF 570
VNAVTWGVF
Sbjct: 577 PAQPADMDLDDLGSNPESVNAVTWGVF 603
[190][TOP]
>UniRef100_C6HED8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6HED8_AJECH
Length = 713
Score = 106 bits (265), Expect = 1e-21
Identities = 72/217 (33%), Positives = 106/217 (48%), Gaps = 36/217 (16%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDY--QFMRPRAKDKKLIEEWAVPLKSVEDIYER 201
+ R WD +P+GRWGD+ +P++G + Y A ++L W P +DI
Sbjct: 406 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVNAAVARRL---WGYPTTK-QDINNI 461
Query: 202 FRLFCLGKLRTNPWSE-----LDGLQPETKII-NEHLEKINTKGFLTINSQPAVNGEKSD 363
F+ G+L PWSE GL ET I +E L+ IN +G+ T+ SQPAVNG ++D
Sbjct: 462 FQRHVSGELHLVPWSEGGAQDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRND 521
Query: 364 SPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKS-- 525
P GWG G G+V+QKA++EFFC +++++ ++ + A N G + S
Sbjct: 522 HPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNVAGDFMSSS 581
Query: 526 ----------------------NVGQTDVNAVTWGVF 570
+ G T V AVTWGVF
Sbjct: 582 PATDATTEDSSGPVDVFLDSNVSPGNTGVTAVTWGVF 618
[191][TOP]
>UniRef100_A6QT35 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6QT35_AJECN
Length = 712
Score = 106 bits (264), Expect = 1e-21
Identities = 72/217 (33%), Positives = 105/217 (48%), Gaps = 36/217 (16%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDY--QFMRPRAKDKKLIEEWAVPLKSVEDIYER 201
+ R WD +P+GRWGD+ +P++G + Y A ++L W P +DI
Sbjct: 405 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVNAAVARRL---WGYPTTK-QDINNI 460
Query: 202 FRLFCLGKLRTNPWSE-----LDGLQPETKII-NEHLEKINTKGFLTINSQPAVNGEKSD 363
F+ G+L PWSE GL ET I +E L IN +G+ T+ SQPAVNG ++D
Sbjct: 461 FQRHVSGELHLVPWSEGGAQDTGGLNAETATIRDELLHLINGRGWWTLASQPAVNGVRND 520
Query: 364 SPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKS-- 525
P GWG G G+V+QKA++EFFC +++++ ++ + A N G + S
Sbjct: 521 HPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNAAGDFMSSS 580
Query: 526 ----------------------NVGQTDVNAVTWGVF 570
+ G T V AVTWGVF
Sbjct: 581 PATDAATEDFSGPVDVFLDSNVSPGNTGVTAVTWGVF 617
[192][TOP]
>UniRef100_B6QFH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QFH8_PENMQ
Length = 710
Score = 103 bits (256), Expect = 1e-20
Identities = 64/155 (41%), Positives = 84/155 (54%), Gaps = 8/155 (5%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDY-QFMRPRAKDKKLIEEWAVPLKSVEDIYERF 204
+ R WD +P+GRWGDS +P++G + Y + A K E W P+ EDI F
Sbjct: 409 LGREATWDDFPNGRWGDSRSPAFGEIDGYGPSLHVNATVAK--ELWGFPVTR-EDIGTLF 465
Query: 205 RLFCLGKLRTNPWSELDG-----LQPETKIINEHL-EKINTKGFLTINSQPAVNGEKSDS 366
R G+L PWSE L ET+II L + I K + T+ SQPAVNG +SD
Sbjct: 466 RKHVSGELYIVPWSEGGAAEDANLNAETQIIKPQLLQIIEKKNWWTLASQPAVNGVRSDH 525
Query: 367 PTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVEKT 468
P GWG PG G+V+QKA++EFFC V+ T
Sbjct: 526 PVFGWGPPGEGFVFQKAFVEFFCPNADYQNKVKPT 560
[193][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 101 bits (252), Expect = 4e-20
Identities = 59/190 (31%), Positives = 102/190 (53%), Gaps = 8/190 (4%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 207
IS ++ WD++P+GR+ D+ +P++G + Y + ++ + W P+ +DI F
Sbjct: 329 ISGSVTWDEFPNGRYTDARSPAFGEMDGYG-ANLKVPPEEAVRLWGTPVDE-DDISSIFS 386
Query: 208 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINT------KGFLTINSQPAVNGEKSDSP 369
F G+L PW ++ + ET + L +N+ K + T+ SQPAV+G S P
Sbjct: 387 RFVDGRLACMPWCDIP-VWDETMQLLPALLHLNSPPSAGGKAWWTVGSQPAVDGCDSTDP 445
Query: 370 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVE--KTKDRPFLTYMAVNKEGVWKSNVGQTD 543
T G+G GGY++QKA++E F ++ +ALV+ + P + +++N+
Sbjct: 446 TFGFGPQGGYIFQKAFVELFMNENDKNALVQMIQGSSTPVTYFAGKCDPTTFETNLTTNG 505
Query: 544 VNAVTWGVFP 573
+N VTWGVFP
Sbjct: 506 LNTVTWGVFP 515
[194][TOP]
>UniRef100_B8MDD4 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8MDD4_TALSN
Length = 713
Score = 100 bits (250), Expect = 6e-20
Identities = 62/155 (40%), Positives = 83/155 (53%), Gaps = 8/155 (5%)
Frame = +1
Query: 28 ISRTIGWDQYPHGRWGDSGNPSYGALTDY-QFMRPRAKDKKLIEEWAVPLKSVEDIYERF 204
+ R WD +P+GRWGDS +P++G + Y + A K + W P+ EDI F
Sbjct: 411 LGREATWDDFPNGRWGDSRSPAFGEIDGYGPSLHVNATVAKQL--WGFPVTR-EDIGALF 467
Query: 205 RLFCLGKLRTNPWSELDG-----LQPETKIINEHL-EKINTKGFLTINSQPAVNGEKSDS 366
R G+L PWSE L ET+ I L + I K + T+ SQPAVNG +SD
Sbjct: 468 RKHVSGELYIVPWSEGGAAEDANLNAETETIKPQLLQIIEKKNWWTLASQPAVNGVRSDH 527
Query: 367 PTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVEKT 468
P GWG PG G+V+QKA++EFFC V+ T
Sbjct: 528 PVFGWGPPGEGFVFQKAFVEFFCPSSDYQNKVKPT 562
[195][TOP]
>UniRef100_Q2HBA5 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2HBA5_CHAGB
Length = 643
Score = 92.0 bits (227), Expect = 3e-17
Identities = 58/138 (42%), Positives = 75/138 (54%)
Frame = +1
Query: 160 WAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQP 339
W P+ S DI F G+L+T PWSE + ET I + L +N+KG+ T+ SQP
Sbjct: 453 WGAPV-SPPDISAIFIRHLRGELQTIPWSE-ESFSAETDKIRDQLVALNSKGWWTLASQP 510
Query: 340 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVW 519
AVNG +S PT GWG G+V+QKA++EFF AL EK +RP EG
Sbjct: 511 AVNGLRSSDPTFGWGPQNGFVFQKAFVEFFLPLADWAAL-EKRLNRP-------EMEG-- 560
Query: 520 KSNVGQTDVNAVTWGVFP 573
+ NAV+WGVFP
Sbjct: 561 -RREREASTNAVSWGVFP 577
[196][TOP]
>UniRef100_A7S359 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
RepID=A7S359_NEMVE
Length = 102
Score = 90.9 bits (224), Expect = 6e-17
Identities = 44/89 (49%), Positives = 58/89 (65%)
Frame = +1
Query: 238 PWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAY 417
PW++ + L ET I E L N+ G L+INSQP+VN S P +GWGG GGY+YQKAY
Sbjct: 5 PWND-EELALETSFIKEKLIHFNSNGILSINSQPSVNAASSTDPLLGWGGEGGYIYQKAY 63
Query: 418 LEFFCSKEKLDALVEKTKDRPFLTYMAVN 504
LEFF S E + L+++ K+ P + Y VN
Sbjct: 64 LEFFASPEVVYILLQELKNYPQVNYHVVN 92
[197][TOP]
>UniRef100_Q497H7 Mthfr protein (Fragment) n=2 Tax=Mus musculus RepID=Q497H7_MOUSE
Length = 166
Score = 71.6 bits (174), Expect = 4e-11
Identities = 35/73 (47%), Positives = 47/73 (64%), Gaps = 1/73 (1%)
Frame = +1
Query: 358 SDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGVWKSNVG 534
S P VGWG GGYV+QKAYLEFF S+E ++AL++ K + Y V+ +G +N
Sbjct: 4 SSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAP 63
Query: 535 QTDVNAVTWGVFP 573
+ NAVTWG+FP
Sbjct: 64 ELQPNAVTWGIFP 76
[198][TOP]
>UniRef100_A6SLU6 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6SLU6_BOTFB
Length = 390
Score = 67.0 bits (162), Expect = 1e-09
Identities = 31/68 (45%), Positives = 47/68 (69%)
Frame = +1
Query: 1 FWANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKS 180
FW NR KSY++RT WD++P+GRWGDS +P++G L Y + + +++ I+ W P KS
Sbjct: 324 FWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDAYG-IGLKGSNEQNIKLWGQP-KS 381
Query: 181 VEDIYERF 204
++DI E F
Sbjct: 382 IKDIAELF 389