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[1][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 343 bits (880), Expect = 5e-93
Identities = 157/189 (83%), Positives = 175/189 (92%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
ANRPKSY++RTIGWDQYPHGRWGDS NPSYGAL+DYQFMRPRA+ KKL+EEWA PLKSVE
Sbjct: 344 ANRPKSYLTRTIGWDQYPHGRWGDSRNPSYGALSDYQFMRPRARGKKLLEEWAAPLKSVE 403
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
DIYE+F+++CLGKL+++PWSELDGLQPETKIINE L KIN KGFLTINSQPAVNGEKSDS
Sbjct: 404 DIYEKFKVYCLGKLKSSPWSELDGLQPETKIINEQLGKINLKGFLTINSQPAVNGEKSDS 463
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDV 541
P+VGWGGPGGYVYQKAYLEFFCSK+KL+ALV+K K PF+TY+AVNK G W SNV TDV
Sbjct: 464 PSVGWGGPGGYVYQKAYLEFFCSKDKLNALVDKCKSFPFVTYIAVNKGGSWISNVALTDV 523
Query: 542 NAVTWGVFP 568
NAVTWGVFP
Sbjct: 524 NAVTWGVFP 532
[2][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 338 bits (866), Expect = 2e-91
Identities = 156/190 (82%), Positives = 173/190 (91%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
ANRPKSY+SRTIGWDQYPHGRWGDS NPSYGAL+DYQFMRPRA+ KKL EEWA PLKSVE
Sbjct: 347 ANRPKSYLSRTIGWDQYPHGRWGDSHNPSYGALSDYQFMRPRARGKKLFEEWASPLKSVE 406
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
DIYE+F+++CLGKL+++PWSEL+GLQPETKIINE L +IN KGFLTINSQPAVN EKSDS
Sbjct: 407 DIYEKFKVYCLGKLKSSPWSELEGLQPETKIINEQLGRINLKGFLTINSQPAVNAEKSDS 466
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDV 541
P+VGWGGPGGYVYQKAYLEFFCSKEKL+ALVE+ K P +TYMAVN+ G W SNV TDV
Sbjct: 467 PSVGWGGPGGYVYQKAYLEFFCSKEKLNALVERCKAFPLVTYMAVNRGGSWISNVALTDV 526
Query: 542 NAVTWGVFPA 571
NAVTWGVFPA
Sbjct: 527 NAVTWGVFPA 536
[3][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 333 bits (854), Expect = 5e-90
Identities = 155/190 (81%), Positives = 170/190 (89%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
ANRP+SYISRTIGWDQYPHGRW DS NPSYG LTDYQFMRPRA+DKKL +EW VPLKS+E
Sbjct: 333 ANRPRSYISRTIGWDQYPHGRWSDSCNPSYGGLTDYQFMRPRARDKKLQDEWVVPLKSIE 392
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
D+ ERF FCLGKL+++PWSELDGLQPE+KIINE L IN+KGFLTINSQPAVNGEKSDS
Sbjct: 393 DVQERFIKFCLGKLKSSPWSELDGLQPESKIINELLGNINSKGFLTINSQPAVNGEKSDS 452
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDV 541
+VGWGGPGGYVYQKAYLEFFCS+EKL+ALV+K K P LTYMAVNKEG W SNVG +V
Sbjct: 453 LSVGWGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHPSLTYMAVNKEGTWMSNVGPGEV 512
Query: 542 NAVTWGVFPA 571
NAVTWGVFPA
Sbjct: 513 NAVTWGVFPA 522
[4][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 330 bits (846), Expect = 5e-89
Identities = 154/190 (81%), Positives = 169/190 (88%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
ANRP+SYISRTIGWDQYPHGRW DS NPSYG LTDYQFMRPRA+DKKL +EW VPLKS+E
Sbjct: 333 ANRPRSYISRTIGWDQYPHGRWSDSCNPSYGGLTDYQFMRPRARDKKLQDEWVVPLKSIE 392
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
D+ ERF FCLGKL+++PWSELDGLQPE+KIINE L IN+KGFLTINSQPAVNGEKSDS
Sbjct: 393 DVQERFIKFCLGKLKSSPWSELDGLQPESKIINELLGNINSKGFLTINSQPAVNGEKSDS 452
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDV 541
+VGWGGPGGYVYQKAYLEFFCS+EKL+ALV+K K LTYMAVNKEG W SNVG +V
Sbjct: 453 LSVGWGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHTSLTYMAVNKEGTWMSNVGPGEV 512
Query: 542 NAVTWGVFPA 571
NAVTWGVFPA
Sbjct: 513 NAVTWGVFPA 522
[5][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 330 bits (846), Expect = 5e-89
Identities = 154/190 (81%), Positives = 169/190 (88%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
ANRP+SYISRTIGWDQYPHGRW DS NPSYG LTDYQFMRPRA+DKKL +EW VPLKS+E
Sbjct: 326 ANRPRSYISRTIGWDQYPHGRWSDSCNPSYGGLTDYQFMRPRARDKKLQDEWVVPLKSIE 385
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
D+ ERF FCLGKL+++PWSELDGLQPE+KIINE L IN+KGFLTINSQPAVNGEKSDS
Sbjct: 386 DVQERFIKFCLGKLKSSPWSELDGLQPESKIINELLGNINSKGFLTINSQPAVNGEKSDS 445
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDV 541
+VGWGGPGGYVYQKAYLEFFCS+EKL+ALV+K K LTYMAVNKEG W SNVG +V
Sbjct: 446 LSVGWGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHTSLTYMAVNKEGTWMSNVGPGEV 505
Query: 542 NAVTWGVFPA 571
NAVTWGVFPA
Sbjct: 506 NAVTWGVFPA 515
[6][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 324 bits (831), Expect = 3e-87
Identities = 151/189 (79%), Positives = 167/189 (88%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
ANRPKSYISRT+GW+QYP GRWGDS NPSYGAL+D+QFMRPRA+DKKL +EW VPL S E
Sbjct: 348 ANRPKSYISRTLGWEQYPQGRWGDSCNPSYGALSDHQFMRPRARDKKLHDEWVVPLSSAE 407
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
DI+E+F+ CLGKL+T+PWSELDGLQPETKIINE L KIN KGFLTINSQPAVNGEKSDS
Sbjct: 408 DIFEKFKKHCLGKLKTSPWSELDGLQPETKIINEQLGKINLKGFLTINSQPAVNGEKSDS 467
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDV 541
P+VGWGGPGGYVYQKAY+EFFCS +KL AL+EK K P LTYMAVN+ G SNVGQ DV
Sbjct: 468 PSVGWGGPGGYVYQKAYIEFFCSTDKLQALLEKCKALPQLTYMAVNRGGTLLSNVGQNDV 527
Query: 542 NAVTWGVFP 568
NAVTWGVFP
Sbjct: 528 NAVTWGVFP 536
[7][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 318 bits (814), Expect = 2e-85
Identities = 150/189 (79%), Positives = 163/189 (86%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
ANRPKSY+ RT+GWDQYPHGRWGDS NPSYGALTD+QF RPR + KKL EEWAVPLKSVE
Sbjct: 333 ANRPKSYLKRTLGWDQYPHGRWGDSRNPSYGALTDHQFTRPRGRGKKLQEEWAVPLKSVE 392
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
DI ERF FC GKL ++PWSELDGLQPETKII++ L KIN KGFLTINSQPAVNGEKSDS
Sbjct: 393 DISERFTNFCQGKLTSSPWSELDGLQPETKIIDDQLVKINQKGFLTINSQPAVNGEKSDS 452
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDV 541
PTVGWGGPGGYVYQKAYLEFFC+KEKLD L+EK K P LTY+AVNK+G SN+ V
Sbjct: 453 PTVGWGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKAFPSLTYIAVNKDGESFSNIAPNAV 512
Query: 542 NAVTWGVFP 568
NAVTWGVFP
Sbjct: 513 NAVTWGVFP 521
[8][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 316 bits (810), Expect = 7e-85
Identities = 150/189 (79%), Positives = 164/189 (86%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
ANRPKSYISRT+GWDQYPHGRWGDS NPSYGALTDYQF RPR + KKL EEWAVP+KSVE
Sbjct: 333 ANRPKSYISRTLGWDQYPHGRWGDSRNPSYGALTDYQFTRPRGRGKKLQEEWAVPVKSVE 392
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
DI ERF FC GKL ++PWSELDGLQPETKII++ L KIN KGFLTINSQPAVNGE+SDS
Sbjct: 393 DINERFMNFCQGKLTSSPWSELDGLQPETKIIDDQLVKINQKGFLTINSQPAVNGERSDS 452
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDV 541
+VGWGGPGGYVYQKAYLEFFCSKEKLD L+EK+K P LTY+AVNK+G SN+ V
Sbjct: 453 TSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIAVNKDGESFSNIPTNAV 512
Query: 542 NAVTWGVFP 568
NAVTWGVFP
Sbjct: 513 NAVTWGVFP 521
[9][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 316 bits (810), Expect = 7e-85
Identities = 150/189 (79%), Positives = 164/189 (86%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
ANRPKSYISRT+GWDQYPHGRWGDS NPSYGALTDYQF RPR + KKL EEWAVP+KSVE
Sbjct: 333 ANRPKSYISRTLGWDQYPHGRWGDSRNPSYGALTDYQFTRPRGRGKKLQEEWAVPVKSVE 392
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
DI ERF FC GKL ++PWSELDGLQPETKII++ L KIN KGFLTINSQPAVNGE+SDS
Sbjct: 393 DINERFMNFCQGKLTSSPWSELDGLQPETKIIDDQLVKINQKGFLTINSQPAVNGERSDS 452
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDV 541
+VGWGGPGGYVYQKAYLEFFCSKEKLD L+EK+K P LTY+AVNK+G SN+ V
Sbjct: 453 TSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIAVNKDGESFSNIPTNAV 512
Query: 542 NAVTWGVFP 568
NAVTWGVFP
Sbjct: 513 NAVTWGVFP 521
[10][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 316 bits (810), Expect = 7e-85
Identities = 149/189 (78%), Positives = 162/189 (85%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
ANRPKSY+ RT+GWDQYPHGRWGDS NPSYGALTD+QF RPR + KKL EEWAVPLKSVE
Sbjct: 333 ANRPKSYLKRTLGWDQYPHGRWGDSRNPSYGALTDHQFTRPRGRGKKLQEEWAVPLKSVE 392
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
DI ERF FC GKL ++PWSELDGLQPETKII++ L IN KGFLTINSQPAVNGEKSDS
Sbjct: 393 DISERFTNFCQGKLTSSPWSELDGLQPETKIIDDQLVNINQKGFLTINSQPAVNGEKSDS 452
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDV 541
PTVGWGGPGGYVYQKAYLEFFC+KEKLD L+EK K P LTY+AVNK+G SN+ V
Sbjct: 453 PTVGWGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKAFPSLTYIAVNKDGETFSNISPNAV 512
Query: 542 NAVTWGVFP 568
NAVTWGVFP
Sbjct: 513 NAVTWGVFP 521
[11][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 309 bits (791), Expect = 1e-82
Identities = 144/190 (75%), Positives = 163/190 (85%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
ANRPKSYISRT GW+ +P GRWGDS + SYGAL+D+QF RPRA+DKKL +EW VPLKSVE
Sbjct: 333 ANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVPLKSVE 392
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
DI E+F+ CLG L+++PWSELDGLQPET+IINE L K+N+KGFLTINSQP+VN E+SDS
Sbjct: 393 DIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDS 452
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDV 541
PTVGWGGP GYVYQKAYLEFFCSKEKLDA+VEK K P +TYMAVNK W SN Q DV
Sbjct: 453 PTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQADV 512
Query: 542 NAVTWGVFPA 571
NAVTWGVFPA
Sbjct: 513 NAVTWGVFPA 522
[12][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 306 bits (784), Expect = 7e-82
Identities = 145/189 (76%), Positives = 162/189 (85%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
ANRPKSYISRT GWDQYPHGRWGDS NPSYGAL D+QF RPR + KKL EEWAVPLKSV+
Sbjct: 321 ANRPKSYISRTTGWDQYPHGRWGDSRNPSYGALNDHQFTRPRGRGKKLQEEWAVPLKSVQ 380
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
DI ERF FC GKL+++PWSELDGLQPET II++ L KIN+KGFLTINSQPAVN EKS+S
Sbjct: 381 DINERFVNFCEGKLKSSPWSELDGLQPETTIIDDQLVKINSKGFLTINSQPAVNAEKSES 440
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDV 541
P+VGWGGPGGYVYQKAY+EFFC+KEKL L+EK+K P LTY+AVNKEG SN+ V
Sbjct: 441 PSVGWGGPGGYVYQKAYVEFFCAKEKLGQLIEKSKAFPSLTYIAVNKEGESISNIPANAV 500
Query: 542 NAVTWGVFP 568
NAVTWGVFP
Sbjct: 501 NAVTWGVFP 509
[13][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 306 bits (783), Expect = 9e-82
Identities = 137/190 (72%), Positives = 166/190 (87%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
ANRP+SYISRTIGW+Q+P+GRWGD+ +P+YGAL DYQF+R R++ KK++EEW VPL S+
Sbjct: 333 ANRPRSYISRTIGWEQFPNGRWGDARSPAYGALNDYQFLRRRSRSKKILEEWVVPLSSIV 392
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
DI E+F FC+GKL++NPWSELDGLQPET INE LE++N KGFLTINSQPAVNGEKSDS
Sbjct: 393 DIQEKFANFCVGKLKSNPWSELDGLQPETVKINEKLEQLNRKGFLTINSQPAVNGEKSDS 452
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDV 541
P++GWGG GYVYQKAY+EFFCS EKL+ LVEK K+ PF+TY+AVNK+G +N+G TDV
Sbjct: 453 PSIGWGGAAGYVYQKAYVEFFCSPEKLNELVEKAKNLPFVTYIAVNKKGATAANIGPTDV 512
Query: 542 NAVTWGVFPA 571
NAVTWGVFPA
Sbjct: 513 NAVTWGVFPA 522
[14][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=B9DHL6_ARATH
Length = 402
Score = 305 bits (781), Expect = 2e-81
Identities = 137/190 (72%), Positives = 161/190 (84%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
ANRPKSYISRT GW+ +PHGRWGDS + +Y L+DYQF RP+ +DKKL +EW VPLKS+E
Sbjct: 143 ANRPKSYISRTKGWNDFPHGRWGDSHSAAYSTLSDYQFARPKGRDKKLQQEWVVPLKSIE 202
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
D+ E+F+ C+G L+++PWSELDGLQPETKIINE L KIN+ GFLTINSQP+VN KSDS
Sbjct: 203 DVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDS 262
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDV 541
P +GWGGPGGYVYQKAYLEFFCSK+KLD LVEK+K P +TYMAVNK W SN G++DV
Sbjct: 263 PAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDV 322
Query: 542 NAVTWGVFPA 571
NAVTWGVFPA
Sbjct: 323 NAVTWGVFPA 332
[15][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 305 bits (781), Expect = 2e-81
Identities = 137/190 (72%), Positives = 161/190 (84%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
ANRPKSYISRT GW+ +PHGRWGDS + +Y L+DYQF RP+ +DKKL +EW VPLKS+E
Sbjct: 333 ANRPKSYISRTKGWNDFPHGRWGDSHSAAYSTLSDYQFARPKGRDKKLQQEWVVPLKSIE 392
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
D+ E+F+ C+G L+++PWSELDGLQPETKIINE L KIN+ GFLTINSQP+VN KSDS
Sbjct: 393 DVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDS 452
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDV 541
P +GWGGPGGYVYQKAYLEFFCSK+KLD LVEK+K P +TYMAVNK W SN G++DV
Sbjct: 453 PAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDV 512
Query: 542 NAVTWGVFPA 571
NAVTWGVFPA
Sbjct: 513 NAVTWGVFPA 522
[16][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 283 bits (724), Expect = 7e-75
Identities = 127/190 (66%), Positives = 156/190 (82%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
ANRP+SYISRT WD++P GRWGD+GNP+YG+ +D+QF+R + + KKL +EWAVPL S E
Sbjct: 333 ANRPRSYISRTTSWDEFPRGRWGDTGNPAYGSFSDHQFLRKKTRSKKLQKEWAVPLNSCE 392
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
D+ + F +C G L T+PWSEL+GLQPET IN+ L +NT+GFLTINSQPAVNGEKSDS
Sbjct: 393 DVNQIFAKYCQGTLSTHPWSELEGLQPETSQINDKLVALNTQGFLTINSQPAVNGEKSDS 452
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDV 541
P+VGWGGPGGYVYQKAY+EFFCS EKL A++EK K P LT++AVN +G +SN+G V
Sbjct: 453 PSVGWGGPGGYVYQKAYVEFFCSPEKLQAVIEKAKSNPSLTFIAVNAKGETQSNIGPNCV 512
Query: 542 NAVTWGVFPA 571
NAVTWGVFPA
Sbjct: 513 NAVTWGVFPA 522
[17][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 280 bits (716), Expect = 6e-74
Identities = 130/190 (68%), Positives = 151/190 (79%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
ANRP+SYISRT WD +P GRWGD+ NP+YG+ +D+QF R + + KKL +EWAVPL S E
Sbjct: 333 ANRPRSYISRTTSWDDFPRGRWGDTANPAYGSFSDHQFTRKKTRSKKLQKEWAVPLNSSE 392
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
D+ F +C G L T+PWSEL+GLQPET INE L +N GFLTINSQPAVNGEKSDS
Sbjct: 393 DVNAIFAKYCQGTLSTHPWSELEGLQPETVQINEKLVALNQGGFLTINSQPAVNGEKSDS 452
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDV 541
P+VGWGGPGGYVYQKAY+EFFCS EKL A++EK K P LTY+AVN +G KSNVG T V
Sbjct: 453 PSVGWGGPGGYVYQKAYVEFFCSPEKLQAVIEKAKTSPSLTYIAVNAKGETKSNVGPTSV 512
Query: 542 NAVTWGVFPA 571
NAVTWGVFPA
Sbjct: 513 NAVTWGVFPA 522
[18][TOP]
>UniRef100_A9P8D1 Putative uncharacterized protein n=1 Tax=Populus trichocarpa
RepID=A9P8D1_POPTR
Length = 224
Score = 265 bits (676), Expect = 2e-69
Identities = 123/151 (81%), Positives = 138/151 (91%)
Frame = +2
Query: 116 MRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEK 295
MRPRA+ KKL+EEWA PLKSVEDIYE+F+++CLGKL+++PWSELDGLQPETKIINE L K
Sbjct: 1 MRPRARGKKLLEEWAAPLKSVEDIYEKFKVYCLGKLKSSPWSELDGLQPETKIINEQLGK 60
Query: 296 INTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRP 475
IN KGFLTINSQPAVNGEKSDSP+VGWGGPGGYVYQKAYLEFFCSK+KL+ALV+K K P
Sbjct: 61 INLKGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYLEFFCSKDKLNALVDKCKSFP 120
Query: 476 FLTYMAVNKEGVWKSNVGQTDVNAVTWGVFP 568
F+TY+AVNK G W SNV TDVNAVTWGVFP
Sbjct: 121 FVTYIAVNKGGSWISNVALTDVNAVTWGVFP 151
[19][TOP]
>UniRef100_A6N158 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Oryza sativa
Indica Group RepID=A6N158_ORYSI
Length = 237
Score = 261 bits (666), Expect = 3e-68
Identities = 126/163 (77%), Positives = 139/163 (85%)
Frame = +2
Query: 80 NPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQ 259
NPSYGALTDYQF RPR + KKL EEWAVP+KSVEDI ERF FC GKL ++PWSELDGLQ
Sbjct: 2 NPSYGALTDYQFTRPRGRGKKLQEEWAVPVKSVEDINERFMNFCQGKLTSSPWSELDGLQ 61
Query: 260 PETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 439
PETKII++ L KIN KGFLTINSQPAVNGE+SDS +VGWGGPGGYVYQKAYLEFFCSKEK
Sbjct: 62 PETKIIDDQLVKINQKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEK 121
Query: 440 LDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFP 568
LD L+EK+K P LTY+AVNK+G SN+ VNAVTWGVFP
Sbjct: 122 LDQLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVFP 164
[20][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 187 bits (475), Expect = 5e-46
Identities = 95/194 (48%), Positives = 119/194 (61%), Gaps = 5/194 (2%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPR----AKDKKLIEEWAVPL 169
+NRPK+Y+ RT WD YP GRWG++ +P+YGAL+D+QFMR A+ +K W
Sbjct: 329 SNRPKAYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHSTGEARREKARAAWGAAP 388
Query: 170 KSVEDIYERFRLFCLGKLRTNPWSELDG-LQPETKIINEHLEKINTKGFLTINSQPAVNG 346
SV+D+ + F + G++ PW+ELDG L E I E L +N G+LTINSQP VNG
Sbjct: 389 ASVDDVKQVFVKYIKGEVSLLPWAELDGGLTAEAAAIREPLAALNANGYLTINSQPRVNG 448
Query: 347 EKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNV 526
SD GWGGPGGYVY KAY+EFFCS E L K P +TY+A G N+
Sbjct: 449 VASDDAVHGWGGPGGYVYGKAYVEFFCSPEAWATLRAKLDAAPSITYLATTAAGSPAGNM 508
Query: 527 GQTDVNAVTWGVFP 568
VNAVTWGVFP
Sbjct: 509 APDAVNAVTWGVFP 522
[21][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 184 bits (467), Expect = 4e-45
Identities = 91/189 (48%), Positives = 126/189 (66%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
ANR KSY++RT WD++P+GRWGD+ +P+YG + Y ++ R +++ E W P ++
Sbjct: 343 ANRAKSYVNRTETWDEFPNGRWGDARSPAYGDVDAYG-VKLRYSNEEAKEMWGAPT-CLD 400
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
D+ F+ FC G+++ PWSE + ET +I++ L K+N GFLTINSQPAV+G +SD
Sbjct: 401 DVKTLFQQFCAGQVKALPWSETP-VARETSVISDKLAKMNQLGFLTINSQPAVDGARSDD 459
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDV 541
GWG GYVYQKAYLEFF S E LDAL+ + + P +TY AVN +G ++N
Sbjct: 460 KVHGWGPKNGYVYQKAYLEFFVSPEDLDALIARIEADPQITYHAVNSQGDMRTNTNSEAP 519
Query: 542 NAVTWGVFP 568
NAVTWGVFP
Sbjct: 520 NAVTWGVFP 528
[22][TOP]
>UniRef100_A8Q9P3 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8Q9P3_MALGO
Length = 515
Score = 179 bits (455), Expect = 1e-43
Identities = 91/191 (47%), Positives = 120/191 (62%), Gaps = 2/191 (1%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRP--RAKDKKLIEEWAVPLKS 175
ANR KSYI RT WD++P+GRWGD+ +P+YG D P R ++ ++ W P +
Sbjct: 252 ANRAKSYIDRTDAWDEFPNGRWGDARSPAYG---DADVFGPYLRQTKEEALDLWGSPT-T 307
Query: 176 VEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKS 355
++D+ F FC G+L PWS+ L ET +INE L +N +GF TINSQPAV+G +S
Sbjct: 308 IQDLQSLFARFCTGELACLPWSDAP-LAKETSVINEPLRALNERGFFTINSQPAVDGARS 366
Query: 356 DSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQT 535
D P GWG GYVYQKAYLEFF S ++LD L+ + P +TY AVN +G ++N
Sbjct: 367 DDPVHGWGPKHGYVYQKAYLEFFVSPQQLDELIARFDAHPQITYHAVNAQGDMRTNTTSD 426
Query: 536 DVNAVTWGVFP 568
NAVTWG FP
Sbjct: 427 APNAVTWGCFP 437
[23][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 178 bits (451), Expect = 3e-43
Identities = 92/199 (46%), Positives = 123/199 (61%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKK--LIEEWAVPLKS 175
A+RPKSYI RT WD +P+GRWG+S +P++G LTDY ++K K L++ W L S
Sbjct: 368 ASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQMWGEELMS 427
Query: 176 VEDIYERFRLFCLG-------KLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E +YE F + G K+ PW++ D L PET ++ + LEK+N +G LTINSQP
Sbjct: 428 EESVYEVFTNYITGQTNRSGHKVMCLPWND-DPLAPETNLLKDELEKVNRRGVLTINSQP 486
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD-RPFLTYMAVNKEGV 511
+NG+ S VGWG GGYV+QKAYLEFF S E + AL++ K P + Y VN +G
Sbjct: 487 NINGKASSDAIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYQIVNVQGR 546
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N NAVTWG+FP
Sbjct: 547 NITNAHDMQPNAVTWGIFP 565
[24][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 177 bits (450), Expect = 4e-43
Identities = 95/199 (47%), Positives = 122/199 (61%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSY+ RT+ WD+YP+GRWG S +P++G L DY +++ +K +L++ W L+S
Sbjct: 352 ASRPKSYVHRTMMWDEYPNGRWGSSASPAFGELKDYHIFYLKNTSKKDELLKMWGEKLES 411
Query: 176 VEDIYERFRLFCLG-------KLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
VED+YE F F G K+ PWS D L ET I + LE IN+KG LTINSQP
Sbjct: 412 VEDVYEIFTCFVSGERNKYGYKVDALPWSN-DALALETLFIKKSLEYINSKGILTINSQP 470
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVN-KEGV 511
VN S GWGGP GYVYQKAYLEFF S E+ L+E + P + Y A++ E +
Sbjct: 471 NVNALPSTHEVFGWGGPNGYVYQKAYLEFFISAERFKTLLEVLPNFPMINYHALDLSESI 530
Query: 512 WKSNVGQTDVNAVTWGVFP 568
SN AVTWGVFP
Sbjct: 531 NVSNSDHHQPIAVTWGVFP 549
[25][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 176 bits (447), Expect = 9e-43
Identities = 96/193 (49%), Positives = 120/193 (62%), Gaps = 4/193 (2%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQF-MRPRAKDKKLIEEWAVPLKSV 178
ANR +SY+SRT WD++P+GRWGDS +P+YG L Y + A D + W P S
Sbjct: 331 ANRTRSYLSRTADWDEFPNGRWGDSRSPAYGDLDGYPVSIGITAPDAYNL--WGHPTTS- 387
Query: 179 EDIYERFRLFCLGKLRTNPWSELDGLQP---ETKIINEHLEKINTKGFLTINSQPAVNGE 349
D++ F FC G L PWS QP ET +I E L K+N G+LTINSQPAV+G
Sbjct: 388 SDLHALFARFCRGDLAKLPWST----QPPASETSLIIEQLAKMNELGYLTINSQPAVDGV 443
Query: 350 KSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVG 529
+SD GWG PGGYVYQKAYLEFF S + L L+ + + P +TY AVNK+G ++N
Sbjct: 444 RSDDKVHGWGPPGGYVYQKAYLEFFVSPDLLSPLIRRIEKDPRITYYAVNKQGDLRTNTH 503
Query: 530 QTDVNAVTWGVFP 568
NAVTWGVFP
Sbjct: 504 SESPNAVTWGVFP 516
[26][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 174 bits (442), Expect = 3e-42
Identities = 88/199 (44%), Positives = 124/199 (62%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L S
Sbjct: 362 ASRPKSYIHRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGQELNS 421
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F + G+ N PW++ D L PET ++ L+K+N +G LTINSQP
Sbjct: 422 EESVFEVFTYYISGEPNPNGHKVNCLPWND-DPLAPETNLLKNELQKVNKRGILTINSQP 480
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD-RPFLTYMAVNKEGV 511
VNG+ S P VGWG GYV+QKAYLEFF S E + AL++ K P + Y VN G
Sbjct: 481 NVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEMVSALIKVLKRYEPRVNYHIVNVHGQ 540
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N NAVTWG+FP
Sbjct: 541 NITNAADLQPNAVTWGIFP 559
[27][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 173 bits (439), Expect = 7e-42
Identities = 90/199 (45%), Positives = 124/199 (62%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSY+ RT WD++P+GRWG S +P++G L DY +++P AK ++L++ W L
Sbjct: 357 ASRPKSYVYRTQEWDEFPNGRWGSSESPAFGELNDYYLFYLKPNAKKEELLDMWGHELTC 416
Query: 176 VEDIYERFRLFCLGK-------LRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
++D+ + F + GK +R PW++ D L ET IN+ L +IN++G LTINSQP
Sbjct: 417 LQDVCDVFTNYITGKESKNGKKVRKIPWND-DDLAAETSFINDKLARINSRGVLTINSQP 475
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVW 514
VN S P VGWG PGGYV+QKAYLEFF S+E + AL + P + Y + EG
Sbjct: 476 NVNAAPSTDPVVGWGTPGGYVFQKAYLEFFTSRENVQALFKVLPKYPNVNYHIIKFEGDD 535
Query: 515 K-SNVGQTDVNAVTWGVFP 568
+N Q AVTWGVFP
Sbjct: 536 DYTNCDQQQPIAVTWGVFP 554
[28][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 172 bits (436), Expect = 2e-41
Identities = 87/199 (43%), Positives = 124/199 (62%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L S
Sbjct: 362 ASRPKSYIHRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGQELSS 421
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F + G+ N PW++ D L PET ++ L+K+N +G LTINSQP
Sbjct: 422 EESVFEVFTYYISGEPNPNGHKVTCLPWND-DPLAPETNLLKSELQKVNKRGILTINSQP 480
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD-RPFLTYMAVNKEGV 511
VNG+ S P VGWG GYV+QKAYLEFF S E + AL++ K P + Y VN G
Sbjct: 481 NVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEMVTALIKVLKRYEPRVNYHIVNVHGQ 540
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N +AVTWG+FP
Sbjct: 541 NITNAADLQPSAVTWGIFP 559
[29][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 171 bits (434), Expect = 3e-41
Identities = 85/200 (42%), Positives = 122/200 (61%), Gaps = 11/200 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
++RPKSYI RT WD++P+GRWG+S PS+ L+D+ +++ + +++ ++ W L
Sbjct: 346 SSRPKSYIHRTSNWDEFPNGRWGNSSAPSFAELSDHHLFYLKSKESEEERLKMWGEKLDC 405
Query: 176 VEDIYERFRLFCLGKLRTNPWSEL--------DGLQPETKIINEHLEKINTKGFLTINSQ 331
+ED+Y F+ + GK N W D LQPET ++++ L +IN GFLT NSQ
Sbjct: 406 IEDVYHVFQCYLSGK--KNKWGYKVKSLPLNDDELQPETSLLSDQLYRINGHGFLTTNSQ 463
Query: 332 PAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGV 511
PAVN S GWGG GGY+YQKAYLEFF K+ +D L+E D P + Y ++ G
Sbjct: 464 PAVNAALSTDERFGWGGAGGYIYQKAYLEFFMHKKNVDFLLEVLNDNPRVNYHIIDSHGC 523
Query: 512 W-KSNVGQTDVNAVTWGVFP 568
+ K+N + AVTWGVFP
Sbjct: 524 YDKTNADRYSPIAVTWGVFP 543
[30][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 171 bits (434), Expect = 3e-41
Identities = 88/188 (46%), Positives = 121/188 (64%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR +SY++RT WD++P+GRWGDS +P++G L Y + + +++ I+ W PL S++D
Sbjct: 327 NRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDSYG-IGLKGTNEQNIKLWGTPL-SIKD 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ + F + GKL + PWSE T I N+ ++ +N +GFLTINSQPAVNG KS P
Sbjct: 385 LSDLFVRYMEGKLESLPWSEQPITGEATSIRNDLID-LNRRGFLTINSQPAVNGAKSSDP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
T GWG GYVYQKAYLE S E + ++ + + P TY AVNK+G K+N N
Sbjct: 444 TFGWGPRNGYVYQKAYLEVLVSPEYIAEIITRIERDPEFTYYAVNKDGDLKTNAPNEGPN 503
Query: 545 AVTWGVFP 568
AVTWGVFP
Sbjct: 504 AVTWGVFP 511
[31][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 171 bits (432), Expect = 5e-41
Identities = 86/199 (43%), Positives = 127/199 (63%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L S
Sbjct: 391 ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTS 450
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F L+ G+ N PW++ + L ET ++ E L ++N +G LTINSQP
Sbjct: 451 EESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINSQP 509
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGV 511
+NG+ S P VGWG GGYV+QKAYLEFF S+E +AL++ K + Y VN +G
Sbjct: 510 NINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGE 569
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N + NAVTWG+FP
Sbjct: 570 NITNAPELQPNAVTWGIFP 588
[32][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform 4
n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 171 bits (432), Expect = 5e-41
Identities = 86/199 (43%), Positives = 127/199 (63%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L S
Sbjct: 409 ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTS 468
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F L+ G+ N PW++ + L ET ++ E L ++N +G LTINSQP
Sbjct: 469 EESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINSQP 527
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGV 511
+NG+ S P VGWG GGYV+QKAYLEFF S+E +AL++ K + Y VN +G
Sbjct: 528 NINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGE 587
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N + NAVTWG+FP
Sbjct: 588 NITNAPELQPNAVTWGIFP 606
[33][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 171 bits (432), Expect = 5e-41
Identities = 86/199 (43%), Positives = 127/199 (63%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L S
Sbjct: 368 ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTS 427
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F L+ G+ N PW++ + L ET ++ E L ++N +G LTINSQP
Sbjct: 428 EESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINSQP 486
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGV 511
+NG+ S P VGWG GGYV+QKAYLEFF S+E +AL++ K + Y VN +G
Sbjct: 487 NINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGE 546
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N + NAVTWG+FP
Sbjct: 547 NITNAPELQPNAVTWGIFP 565
[34][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 170 bits (430), Expect = 8e-41
Identities = 87/198 (43%), Positives = 120/198 (60%), Gaps = 10/198 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKK--LIEEWAVPLKS 175
++RPKSYI RT WD +P+GRWG+S +P++G L DY ++K K L++ W L S
Sbjct: 372 SSRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALLQMWGEELLS 431
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F + + + PW++ + L PET ++ + LEK+N +G LTINSQP
Sbjct: 432 EESVFEVFTCYITAQTNRSGQKVLCLPWND-EPLAPETNLLKDELEKVNRRGVLTINSQP 490
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD-RPFLTYMAVNKEGV 511
+NG+ S P VGWG GGYVYQKAYLEFF S E + AL++ K P + Y VN G
Sbjct: 491 NINGKPSTDPIVGWGPAGGYVYQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGR 550
Query: 512 WKSNVGQTDVNAVTWGVF 565
+N NAVTWG+F
Sbjct: 551 NLTNAPDMQPNAVTWGIF 568
[35][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 170 bits (430), Expect = 8e-41
Identities = 87/198 (43%), Positives = 120/198 (60%), Gaps = 10/198 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKK--LIEEWAVPLKS 175
++RPKSYI RT WD +P+GRWG+S +P++G L DY ++K K L++ W L S
Sbjct: 372 SSRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALLQMWGEELLS 431
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F + + + PW++ + L PET ++ + LEK+N +G LTINSQP
Sbjct: 432 EESVFEVFTCYITAQTNRSGQKVLCLPWND-EPLAPETNLLKDELEKVNRRGVLTINSQP 490
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD-RPFLTYMAVNKEGV 511
+NG+ S P VGWG GGYVYQKAYLEFF S E + AL++ K P + Y VN G
Sbjct: 491 NINGKPSTDPIVGWGPAGGYVYQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGR 550
Query: 512 WKSNVGQTDVNAVTWGVF 565
+N NAVTWG+F
Sbjct: 551 NLTNAPDMQPNAVTWGIF 568
[36][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 169 bits (429), Expect = 1e-40
Identities = 86/199 (43%), Positives = 126/199 (63%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ + L++ W L S
Sbjct: 391 ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEELTS 450
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F L+ G+ N PW++ + L ET ++ E L ++N +G LTINSQP
Sbjct: 451 EESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINSQP 509
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGV 511
+NG+ S P VGWG GGYV+QKAYLEFF S+E +AL++ K + Y VN +G
Sbjct: 510 NINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGE 569
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N + NAVTWG+FP
Sbjct: 570 NITNAPELQPNAVTWGIFP 588
[37][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 169 bits (429), Expect = 1e-40
Identities = 86/199 (43%), Positives = 126/199 (63%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ + L++ W L S
Sbjct: 409 ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEELTS 468
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F L+ G+ N PW++ + L ET ++ E L ++N +G LTINSQP
Sbjct: 469 EESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINSQP 527
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGV 511
+NG+ S P VGWG GGYV+QKAYLEFF S+E +AL++ K + Y VN +G
Sbjct: 528 NINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGE 587
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N + NAVTWG+FP
Sbjct: 588 NITNAPELQPNAVTWGIFP 606
[38][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 169 bits (429), Expect = 1e-40
Identities = 86/199 (43%), Positives = 126/199 (63%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ + L++ W L S
Sbjct: 368 ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEELTS 427
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F L+ G+ N PW++ + L ET ++ E L ++N +G LTINSQP
Sbjct: 428 EESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINSQP 486
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGV 511
+NG+ S P VGWG GGYV+QKAYLEFF S+E +AL++ K + Y VN +G
Sbjct: 487 NINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGE 546
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N + NAVTWG+FP
Sbjct: 547 NITNAPELQPNAVTWGIFP 565
[39][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 169 bits (428), Expect = 1e-40
Identities = 86/199 (43%), Positives = 123/199 (61%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSYI RT WD +P+GRWG+S +P++G L DY +++ ++ ++L++ W L
Sbjct: 370 ASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTG 429
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F + G+ N PW++ D L ET ++ + LEK+N +G LTINSQP
Sbjct: 430 EESVFEVFTCYITGEPNKNGYKVTCMPWND-DPLATETNLLKDQLEKVNRRGILTINSQP 488
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGV 511
+NG+ S P VGWG GGYV+QKAYLEFF S E + AL++ K + Y VN +G
Sbjct: 489 NINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVQGQ 548
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N NAVTWG+FP
Sbjct: 549 NITNAPDLQPNAVTWGIFP 567
[40][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 169 bits (427), Expect = 2e-40
Identities = 93/190 (48%), Positives = 115/190 (60%), Gaps = 1/190 (0%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ-FMRPRAKDKKLIEEWAVPLKSV 178
ANR KSYISRT WD+YP+GR+GDS +P+YG L Y +++ KD ++ W P S
Sbjct: 327 ANRTKSYISRTENWDEYPNGRFGDSRSPAYGELDGYGVWIKQTVKDA--LKLWGHPT-SF 383
Query: 179 EDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSD 358
DI F FC KL PWS+ Q ET +I E L +N GFLTINSQPAVN +SD
Sbjct: 384 ADIASLFSRFCTKKLSALPWSDQAPSQ-ETSVIAEQLATMNEFGFLTINSQPAVNSARSD 442
Query: 359 SPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTD 538
P GWG GYVYQKAYLEFF + L+ L+ + +TY +NK G ++N
Sbjct: 443 DPVFGWGPSNGYVYQKAYLEFFVNPTLLNLLLTHIERDSNITYYVINKRGDLRTNTHSDG 502
Query: 539 VNAVTWGVFP 568
NAVTWGVFP
Sbjct: 503 PNAVTWGVFP 512
[41][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 168 bits (426), Expect = 2e-40
Identities = 87/199 (43%), Positives = 123/199 (61%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKK--LIEEWAVPLKS 175
A+RPKSYI RT WD++P+GRWG+S +P++G L DY ++K + L++ W L S
Sbjct: 362 ASRPKSYIYRTQAWDEFPNGRWGNSSSPAFGELKDYYLFCLKSKTPRTELLKMWGEELTS 421
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F + G+ N PW++ + L ET ++ E L K+N +G LTINSQP
Sbjct: 422 EESVFEVFTYYLSGEPNQNGYKVTCLPWND-EPLAAETSLMKEELLKVNQRGILTINSQP 480
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGV 511
+NG+ S P VGWG GGYV+QKAYLEFF S E ++AL++ K + Y VN +G
Sbjct: 481 NINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSETVEALLQVLKKYELRVNYHIVNVKGE 540
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N + NAVTWG+FP
Sbjct: 541 NITNAPELQPNAVTWGIFP 559
[42][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 168 bits (426), Expect = 2e-40
Identities = 85/199 (42%), Positives = 126/199 (63%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L S
Sbjct: 398 ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTS 457
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
++E F L+ G+ N PW++ + L ET ++ E L ++N +G LTINSQP
Sbjct: 458 EASVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINSQP 516
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGV 511
+NG+ S P VGWG GGYV+QKAYLEFF S+E +AL++ K + Y VN +G
Sbjct: 517 NINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGE 576
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N + NAVTWG+FP
Sbjct: 577 NITNAPELQPNAVTWGIFP 595
[43][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 168 bits (426), Expect = 2e-40
Identities = 90/189 (47%), Positives = 114/189 (60%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
ANR KSYISRT WD+YP+GR+GDS +P+YG + Y + K+ L + W P ++E
Sbjct: 287 ANRTKSYISRTENWDEYPNGRFGDSRSPAYGEIDGYGTAIKQTKENAL-KLWGYPT-TLE 344
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
++ F FC G+L PWS+ ET II L K+N GFLTINSQPAVNG +SD
Sbjct: 345 EVSVLFAKFCKGELDALPWSD-SAPSKETSIIATQLAKMNELGFLTINSQPAVNGARSDD 403
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDV 541
GWG GYVYQKAYLEFF L L++ + +TY +NK G ++N
Sbjct: 404 KIFGWGPSNGYVYQKAYLEFFVDPALLQLLLKHLERDTNITYHVINKRGDLQTNTHSEGP 463
Query: 542 NAVTWGVFP 568
NAVTWGVFP
Sbjct: 464 NAVTWGVFP 472
[44][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 167 bits (424), Expect = 4e-40
Identities = 84/199 (42%), Positives = 127/199 (63%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSYI RT GWD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L S
Sbjct: 373 ASRPKSYIYRTQGWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTS 432
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F + G+ + PW++ + L ET ++ E L ++N G LTINSQP
Sbjct: 433 EESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINSQP 491
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGV 511
+NG+ S P VGWG GGYV+QKAYLEFF S+E ++AL++ K + Y V+ +G
Sbjct: 492 NINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGE 551
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N + NAVTWG+FP
Sbjct: 552 NITNAPELQPNAVTWGIFP 570
[45][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 167 bits (424), Expect = 4e-40
Identities = 84/199 (42%), Positives = 127/199 (63%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSYI RT GWD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L S
Sbjct: 408 ASRPKSYIYRTQGWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTS 467
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F + G+ + PW++ + L ET ++ E L ++N G LTINSQP
Sbjct: 468 EESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINSQP 526
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGV 511
+NG+ S P VGWG GGYV+QKAYLEFF S+E ++AL++ K + Y V+ +G
Sbjct: 527 NINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGE 586
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N + NAVTWG+FP
Sbjct: 587 NITNAPELQPNAVTWGIFP 605
[46][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 167 bits (424), Expect = 4e-40
Identities = 85/188 (45%), Positives = 117/188 (62%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR +SY++RT WD++P+GRWGDS +P++G L Y + + +++ ++ W P+ + D
Sbjct: 327 NRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDSYG-IGLKGTNEQNVKLWGSPM-CIRD 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ + F + GKL + PWSE + E I L +N +GFLTINSQPAVNG KS P
Sbjct: 385 LSDLFVRYMEGKLDSLPWSE-QAITTEAGPIRSDLIDLNRRGFLTINSQPAVNGAKSSDP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG GYVYQKAYLE F S E + ++ + + P TY AVNK+G K+N N
Sbjct: 444 VFGWGPRNGYVYQKAYLEVFVSPEYISEIITRLERDPEFTYYAVNKDGDLKTNAPNEGPN 503
Query: 545 AVTWGVFP 568
AVTWGVFP
Sbjct: 504 AVTWGVFP 511
[47][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 167 bits (422), Expect = 7e-40
Identities = 84/199 (42%), Positives = 126/199 (63%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L S
Sbjct: 367 ATRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTS 426
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F + G+ N PW++ + L ET ++ E L ++N +G LTINSQP
Sbjct: 427 EESVFEVFAHYLSGEPNQNGYKVTCLPWND-EPLAAETSLMKEELLRVNRQGVLTINSQP 485
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGV 511
+NG+ S P VGWG GGYV+QKAYLEFF S+E ++AL++ K + Y V+ +G
Sbjct: 486 NINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGE 545
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N + NAVTWG+FP
Sbjct: 546 NITNAPELQPNAVTWGIFP 564
[48][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 167 bits (422), Expect = 7e-40
Identities = 85/199 (42%), Positives = 124/199 (62%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQF--MRPRAKDKKLIEEWAVPLKS 175
A+RPKSYI RT WD++P+GRWG+S +P++G L +Y ++ ++ ++L++ W L S
Sbjct: 365 ASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKNYYLFCLKSKSPREELLKMWGQELTS 424
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F + G+ N PW++ + L ET ++ E L+K+N +G LTINSQP
Sbjct: 425 EESVFEVFAYYLSGEPNQNGYKVTCLPWND-EPLAAETSLLKEELQKVNRRGILTINSQP 483
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGV 511
+NG+ S P VGWG GGYV+QKAYLEFF S E + AL++ K + Y VN +G
Sbjct: 484 NINGKPSADPVVGWGPSGGYVFQKAYLEFFTSSETVAALLKVLKKYELRVNYHIVNVKGE 543
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N NAVTWG+FP
Sbjct: 544 NITNAPDMQPNAVTWGIFP 562
[49][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 166 bits (421), Expect = 9e-40
Identities = 89/198 (44%), Positives = 118/198 (59%), Gaps = 11/198 (5%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKSV 178
+RPKSYI RT GWD++P+GRWGDS +P++G L DY F+R R KL W L S
Sbjct: 342 DRPKSYIHRTQGWDEFPNGRWGDSASPAFGELKDYHLFFLRSRTAKDKLRSLWGKELTSE 401
Query: 179 EDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQPA 337
D+++ F+ F G + N PW++ DGL PET +++ L + N G LTINSQP
Sbjct: 402 ADVWKVFKHFITGAVNENGVKVTETPWND-DGLSPETNVLSSTLSRYNELGVLTINSQPN 460
Query: 338 VNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDAL-VEKTKDRPFLTYMAVNKEGVW 514
VN S P GWG GGY+ QKAYLEFF +K +AL K P + Y +NK G
Sbjct: 461 VNAVPSTHPIYGWGDKGGYISQKAYLEFFINKHYAEALKTVLPKYHPRVNYHMINKCGTT 520
Query: 515 -KSNVGQTDVNAVTWGVF 565
+N +++ NAVTWG+F
Sbjct: 521 DHTNADRSNPNAVTWGIF 538
[50][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 166 bits (421), Expect = 9e-40
Identities = 83/199 (41%), Positives = 127/199 (63%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L S
Sbjct: 367 ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTS 426
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E +++ F + G+ N PW++ + L ET ++ E L ++N +G LTINSQP
Sbjct: 427 EESVFQVFAHYLSGEPNQNGYKVTCLPWND-EPLAAETSLMKEELLRVNRRGILTINSQP 485
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGV 511
+NG+ S P VGWG GGYV+QKAYLEFF S+E ++AL++ K + Y V+ +G
Sbjct: 486 NINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGE 545
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N + NAVTWG+FP
Sbjct: 546 NITNAPELQPNAVTWGIFP 564
[51][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
RepID=UPI0000E814FF
Length = 508
Score = 166 bits (420), Expect = 1e-39
Identities = 87/200 (43%), Positives = 120/200 (60%), Gaps = 11/200 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKD---KKLIEEWAVPLK 172
A+RPKSYI RT WD +P+GRWG+S +P++G L DY ++K ++L++ W L
Sbjct: 226 ASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKPSPREELLKMWGEELT 285
Query: 173 SVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQ 331
E ++E F + G+ N PW++ D L ET ++ E LEK+N +G LTINSQ
Sbjct: 286 GEESVFEVFTCYITGEPNKNGHRVTCMPWND-DPLATETSLLKEQLEKVNRRGILTINSQ 344
Query: 332 PAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEG 508
P +NG+ S P GWG GGYV+QKAYLEFF S E + AL++ K + Y VN +G
Sbjct: 345 PNINGKPSTDPIFGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYELRVNYHIVNVKG 404
Query: 509 VWKSNVGQTDVNAVTWGVFP 568
+N NAVTWG+FP
Sbjct: 405 QNITNAPDLQPNAVTWGIFP 424
[52][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Canis lupus familiaris RepID=UPI00005A03BF
Length = 780
Score = 165 bits (418), Expect = 2e-39
Identities = 84/199 (42%), Positives = 126/199 (63%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L S
Sbjct: 493 ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTS 552
Query: 176 VEDIYERFRLFCLG-------KLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F + G K+ PW++ + L ET ++ E L ++N +G LTINSQP
Sbjct: 553 EESVFEVFARYLSGEPNQHGYKVTCLPWND-EPLAAETSLMKEELLRVNRQGILTINSQP 611
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGV 511
+NG+ S P VGWG GGYV+QKAYLEFF S+E + AL++ K + Y V+ +G
Sbjct: 612 NINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGE 671
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N + NAVTWG+FP
Sbjct: 672 NITNAPELQPNAVTWGIFP 690
[53][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 165 bits (418), Expect = 2e-39
Identities = 84/199 (42%), Positives = 126/199 (63%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L S
Sbjct: 409 ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTS 468
Query: 176 VEDIYERFRLFCLG-------KLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F + G K+ PW++ + L ET ++ E L ++N +G LTINSQP
Sbjct: 469 EESVFEVFARYLSGEPNQHGYKVTCLPWND-EPLAAETSLMKEELLRVNRQGILTINSQP 527
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGV 511
+NG+ S P VGWG GGYV+QKAYLEFF S+E + AL++ K + Y V+ +G
Sbjct: 528 NINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGE 587
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N + NAVTWG+FP
Sbjct: 588 NITNAPELQPNAVTWGIFP 606
[54][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 165 bits (417), Expect = 3e-39
Identities = 86/188 (45%), Positives = 117/188 (62%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR KSY++RT WD++P+GRWGDS +P++G L Y + + +++ I+ W P KS++D
Sbjct: 327 NRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDAYG-IGLKGSNEQNIKLWGQP-KSIKD 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
I E F + + + PWSE + E II L ++N +GFLTINSQPAV+G KS P
Sbjct: 385 IAELFVSYLENGIESLPWSEAP-ISSEADIIKSDLIELNRRGFLTINSQPAVDGVKSSDP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG GYVYQKAYLE + + + LV + + P LTY AV K G ++N N
Sbjct: 444 VYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQHDPDLTYYAVKKTGDLQTNAQSDGPN 503
Query: 545 AVTWGVFP 568
AVTWGVFP
Sbjct: 504 AVTWGVFP 511
[55][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 165 bits (417), Expect = 3e-39
Identities = 83/199 (41%), Positives = 126/199 (63%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L S
Sbjct: 367 ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTS 426
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E +++ F G+ N PW++ + L ET ++ E L ++N +G LTINSQP
Sbjct: 427 EESVFQVFAHHLSGEPNQNGYKVTCLPWND-EPLAAETSLMKEELLRVNRRGILTINSQP 485
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGV 511
+NG+ S P VGWG GGYV+QKAYLEFF S+E ++AL++ K + Y V+ +G
Sbjct: 486 NINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGE 545
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N + NAVTWG+FP
Sbjct: 546 NITNAPELQPNAVTWGIFP 564
[56][TOP]
>UniRef100_UPI0000ECA34F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Gallus
gallus RepID=UPI0000ECA34F
Length = 640
Score = 164 bits (414), Expect = 6e-39
Identities = 86/200 (43%), Positives = 119/200 (59%), Gaps = 11/200 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAK---DKKLIEEWAVPLK 172
A+RPKSYI RT WD +P+GRWG+S +P++G L DY ++ ++L++ W L
Sbjct: 358 ASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSSLPPREELLKMWGEELT 417
Query: 173 SVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQ 331
E ++E F + G+ N PW++ D L ET ++ E LEK+N +G LTINSQ
Sbjct: 418 GEESVFEVFTCYITGEPNKNGHRVTCMPWND-DPLATETSLLKEQLEKVNRRGILTINSQ 476
Query: 332 PAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEG 508
P +NG+ S P GWG GGYV+QKAYLEFF S E + AL++ K + Y VN +G
Sbjct: 477 PNINGKPSTDPIFGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYELRVNYHIVNVKG 536
Query: 509 VWKSNVGQTDVNAVTWGVFP 568
+N NAVTWG+FP
Sbjct: 537 QNITNAPDLQPNAVTWGIFP 556
[57][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 163 bits (413), Expect = 8e-39
Identities = 83/199 (41%), Positives = 123/199 (61%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSY+ RT WD++P+GRWG+S P++ +D+ ++R +AK +++++ W L
Sbjct: 313 ASRPKSYLYRTSDWDEFPNGRWGNSSAPAFRDFSDHHLFYLRSKAKKEQMLKMWGQQLND 372
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
V+D++E F+ + G+ N PW++ + L ET I E L N+ G L+INSQP
Sbjct: 373 VQDVFEVFKCYISGEKNENGVKVTSLPWND-EELALETSFIKEKLIHFNSNGILSINSQP 431
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNK-EGV 511
+VN S P +GWGG GGY+YQKAYLEFF S E + L+++ K+ P + Y VN + V
Sbjct: 432 SVNAASSTDPLLGWGGEGGYIYQKAYLEFFASPEVVYILLQELKNYPQVNYHVVNNHDTV 491
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N AVTWGVFP
Sbjct: 492 DITNCDSQTPVAVTWGVFP 510
[58][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 163 bits (413), Expect = 8e-39
Identities = 86/187 (45%), Positives = 115/187 (61%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR SYI+RT WD+YP+GRW D+ +P++G L Y +R + +++ I+ W P KS++D
Sbjct: 328 NRNASYIARTADWDEYPNGRWTDARSPAFGELNAYG-VRLKGTNEQNIKLWGAP-KSIKD 385
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ + F + GK+ PWS+ + PET I L +N +GFLTINSQPAVNG KS P
Sbjct: 386 LSDIFVRYLNGKVERLPWSD-SAVTPETSDIQNELLDLNKRGFLTINSQPAVNGVKSTDP 444
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG GYVYQKAYLE E +D L+ + + P LTY VNK G K+ N
Sbjct: 445 VHGWGPRNGYVYQKAYLELLVPPEHVDELLRRIEKNPDLTYYCVNKTGELKAR-SDEGPN 503
Query: 545 AVTWGVF 565
AVTWG+F
Sbjct: 504 AVTWGIF 510
[59][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 163 bits (412), Expect = 1e-38
Identities = 85/188 (45%), Positives = 114/188 (60%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR KSY+ RT WD++P+GRWGDS +P++G L Y + + ++W P K+++D
Sbjct: 327 NRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGSNEANR-KKWGEP-KAIQD 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
I E F + K+ + PWSE L E I + L ++N +G LTINSQPAVNG KS P
Sbjct: 385 IAELFVSYLNNKIESLPWSE-SPLTTEADEIRDDLIELNKRGLLTINSQPAVNGVKSSHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG GYVYQK+YLE D ++ + ++ P LTY AV K+G +SNV N
Sbjct: 444 IHGWGPDNGYVYQKSYLELLVHPGVFDKMISRIENHPDLTYYAVTKDGELRSNVTSDGPN 503
Query: 545 AVTWGVFP 568
AVTWGVFP
Sbjct: 504 AVTWGVFP 511
[60][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 163 bits (412), Expect = 1e-38
Identities = 90/194 (46%), Positives = 116/194 (59%), Gaps = 5/194 (2%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTD----YQFMRPRAKDKKLIEEWAVPL 169
ANRPKSY+ RT WD++P+GRWGDS +P++G L++ Y F D++ + + P
Sbjct: 362 ANRPKSYVLRTEDWDEFPNGRWGDSTSPAFGELSNFSHYYSFSLGSEDDQRNMLG-SNPT 420
Query: 170 KSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGE 349
KS ED+YE F L+ GK+ PW E LQPE+ +I L +N GFLTINSQP+VN
Sbjct: 421 KS-EDVYEVFALYIEGKIPHIPWCEAT-LQPESFLIQTKLAALNRAGFLTINSQPSVNAA 478
Query: 350 KSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEG-VWKSNV 526
S + GWGGPGGY+YQKAY E FCS E + LV K + AVN G +
Sbjct: 479 LSTHESFGWGGPGGYIYQKAYCECFCSPENMRCLVNMVKQNQSMNVYAVNNAGNCIQEGT 538
Query: 527 GQTDVNAVTWGVFP 568
V A+TWGVFP
Sbjct: 539 ELGGVTALTWGVFP 552
[61][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 162 bits (411), Expect = 1e-38
Identities = 82/199 (41%), Positives = 125/199 (62%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L S
Sbjct: 408 ASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTS 467
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F + G+ + PW++ + L ET ++ E L ++N G LTINSQP
Sbjct: 468 EESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINSQP 526
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGV 511
+N + S P VGWG GGYV+QKAYLEFF S+E ++AL++ K + Y V+ +G
Sbjct: 527 NINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGE 586
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N + NAVTWG+FP
Sbjct: 587 NITNAPELQPNAVTWGIFP 605
[62][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 162 bits (411), Expect = 1e-38
Identities = 82/199 (41%), Positives = 125/199 (62%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L S
Sbjct: 408 ASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTS 467
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F + G+ + PW++ + L ET ++ E L ++N G LTINSQP
Sbjct: 468 EESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINSQP 526
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGV 511
+N + S P VGWG GGYV+QKAYLEFF S+E ++AL++ K + Y V+ +G
Sbjct: 527 NINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGE 586
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N + NAVTWG+FP
Sbjct: 587 NITNAPELQPNAVTWGIFP 605
[63][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 162 bits (411), Expect = 1e-38
Identities = 82/199 (41%), Positives = 125/199 (62%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L S
Sbjct: 408 ASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTS 467
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F + G+ + PW++ + L ET ++ E L ++N G LTINSQP
Sbjct: 468 EESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINSQP 526
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGV 511
+N + S P VGWG GGYV+QKAYLEFF S+E ++AL++ K + Y V+ +G
Sbjct: 527 NINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGE 586
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N + NAVTWG+FP
Sbjct: 587 NITNAPELQPNAVTWGIFP 605
[64][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 162 bits (411), Expect = 1e-38
Identities = 82/199 (41%), Positives = 125/199 (62%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L S
Sbjct: 367 ASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTS 426
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F + G+ + PW++ + L ET ++ E L ++N G LTINSQP
Sbjct: 427 EESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINSQP 485
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGV 511
+N + S P VGWG GGYV+QKAYLEFF S+E ++AL++ K + Y V+ +G
Sbjct: 486 NINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGE 545
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N + NAVTWG+FP
Sbjct: 546 NITNAPELQPNAVTWGIFP 564
[65][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 162 bits (409), Expect = 2e-38
Identities = 84/187 (44%), Positives = 118/187 (63%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
+R +SY++RT WD++P+GRW DS +P++G L Y + + +++ I+ W P KSV+D
Sbjct: 327 HRHQSYVARTQSWDEFPNGRWTDSRSPAFGELDVYG-IGLKGTNEQNIKLWGEP-KSVKD 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ + F F GKL PWSE + E+ II + L +N +GFLTINSQPA+NG KS P
Sbjct: 385 LSDIFIRFLEGKLDRLPWSE-SAITQESDIIKDDLIALNNRGFLTINSQPAINGAKSSHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG GYVYQKAYLE S +D ++ + + P LTY +NK G ++N T N
Sbjct: 444 IYGWGPKNGYVYQKAYLELLISPTLIDEVIRRIETNPDLTYHCINKNGELRTNSSDTP-N 502
Query: 545 AVTWGVF 565
AVTWG+F
Sbjct: 503 AVTWGIF 509
[66][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 159 bits (402), Expect = 1e-37
Identities = 82/188 (43%), Positives = 120/188 (63%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR +SY++RT WD++P+GRWGDS +P++G L Y + R +K++E W P K+V+D
Sbjct: 327 NRKQSYVARTQDWDEFPNGRWGDSRSPAFGELETYGVLL-RQSPQKVLELWGEP-KTVDD 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ + GKL + PWS++ + E + I + ++N +G LTINSQPAVNG KS P
Sbjct: 385 LKTLLVNYLNGKLASLPWSDVP-ISNEIETIKPQILELNNRGILTINSQPAVNGAKSTHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG GYVYQKAYLE + E + LV+K +++ +T+ AVNK G ++N N
Sbjct: 444 VHGWGPKNGYVYQKAYLELLVTPEVAEKLVKKLENQSEITFYAVNKTGNLQTN-APGGPN 502
Query: 545 AVTWGVFP 568
AVTWG++P
Sbjct: 503 AVTWGIYP 510
[67][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 158 bits (400), Expect = 2e-37
Identities = 82/187 (43%), Positives = 109/187 (58%)
Frame = +2
Query: 8 RPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDI 187
R +SY+SRT WD+ PHGRWGDS +P++G ++ R K++ W P KS +I
Sbjct: 331 RNESYVSRTDQWDELPHGRWGDSRSPAFGEFDAIRYGL-RMSPKEITTSWGSP-KSYSEI 388
Query: 188 YERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPT 367
+ F +C K+ + PWS+L + E +I + L +N FLTINSQPA+NGEKS P
Sbjct: 389 GDLFARYCEKKISSLPWSDLP-ISDEADLIRDQLLSMNRNAFLTINSQPALNGEKSSHPV 447
Query: 368 VGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVNA 547
GWG P GYV+QK Y+EFF L+ L E K ++Y NK G +N NA
Sbjct: 448 FGWGPPNGYVFQKPYVEFFVHPSLLNELKETVKKLNSVSYFVTNKNGDLDTNSQYEIPNA 507
Query: 548 VTWGVFP 568
VTWGVFP
Sbjct: 508 VTWGVFP 514
[68][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 158 bits (399), Expect = 3e-37
Identities = 85/187 (45%), Positives = 115/187 (61%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR SY++RT WD+YP+GRW DS +P++G L Y + + +++ I+ W P KS++D
Sbjct: 327 NRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDAYG-VGLKGTNEQNIKLWGEP-KSIKD 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
I + F F GKL PWS+ + E I E L K+N +GFLTINSQPAVNG KS P
Sbjct: 385 ISDIFVNFLTGKLDRLPWSD-SPITTEAHEIQEDLLKLNQRGFLTINSQPAVNGVKSSHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG G+VYQKAYLE +D L+ + + LTY A NK+G K+N + N
Sbjct: 444 VYGWGPKNGFVYQKAYLELLVPSNLIDELITRIEKNDDLTYHATNKKGELKTNT-RDSPN 502
Query: 545 AVTWGVF 565
A+TWG+F
Sbjct: 503 ALTWGIF 509
[69][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 157 bits (397), Expect = 5e-37
Identities = 85/204 (41%), Positives = 117/204 (57%), Gaps = 16/204 (7%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQF---------------MRPRAKDK 139
NRP+SYI+RT WD++P+GRWGD +P++G L+DY D
Sbjct: 327 NRPRSYIARTGSWDEFPNGRWGDYRSPAFGDLSDYHLGGVTPPPGGSANNNTTTTTTGDS 386
Query: 140 KLIEE-WAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFL 316
++ + +S +D+Y F +C G ++ PW++ L E++ I E L +N GFL
Sbjct: 387 VVVPNIYGDSPQSEQDVYNVFASYCSGNIKRLPWND-SPLSLESENIKEQLVFLNKNGFL 445
Query: 317 TINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAV 496
TINSQPA+NG S GWGG G VY+KAY+EFF S E L+E K P +TY AV
Sbjct: 446 TINSQPAINGLPSTDKQHGWGGKNGIVYKKAYIEFFASPENTLKLIEYFKKCPMITYHAV 505
Query: 497 NKEGVWKSNVGQTDVNAVTWGVFP 568
N++G K+N T NAVTWG+FP
Sbjct: 506 NRKGDSKTNTKGT--NAVTWGIFP 527
[70][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 156 bits (395), Expect = 9e-37
Identities = 83/188 (44%), Positives = 111/188 (59%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR KSYI+RT WD++P+GRWGDS +P++G L Y + + ++W P ++V+D
Sbjct: 327 NRNKSYITRTQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGSNELNR-KKWGEP-QTVKD 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
I F + +L PWSE + E ++I + L +N +G +TINSQPAVNG KS P
Sbjct: 385 IANLFVRYLNQELEYLPWSEAP-ISSEAELIKDDLIALNNRGLITINSQPAVNGVKSTHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG GYVYQKAYLE S E + + +D P +TY AV K G +N N
Sbjct: 444 VHGWGPANGYVYQKAYLELLVSPELFPEIKRRIEDHPDITYYAVTKSGNLHTNAPSEGPN 503
Query: 545 AVTWGVFP 568
AVTWGVFP
Sbjct: 504 AVTWGVFP 511
[71][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 156 bits (395), Expect = 9e-37
Identities = 82/187 (43%), Positives = 114/187 (60%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR SYI+RT WD+YP+GRW D+ +P++G L Y +R + +++ I+ W P KS++D
Sbjct: 328 NRNASYIARTADWDEYPNGRWTDARSPAFGELNAYG-VRLKGTNEQNIKLWGAP-KSIKD 385
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ + F + GKL PWS+ + ET I L +N +GFLTINSQPAVNG KS P
Sbjct: 386 LSDIFLRYLNGKLERLPWSD-SSVTLETSDIQNELLDLNKRGFLTINSQPAVNGVKSTDP 444
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG G+VYQKAYLE E ++ L+ + + P LTY +NK G ++ N
Sbjct: 445 VHGWGPRNGFVYQKAYLELLVPPEHVEELLRRIEKNPDLTYYCINKTGELRAR-SDEGPN 503
Query: 545 AVTWGVF 565
AVTWG+F
Sbjct: 504 AVTWGIF 510
[72][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 155 bits (392), Expect = 2e-36
Identities = 82/187 (43%), Positives = 114/187 (60%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
+R +SY++RT WD++P+GRW DS +P++G L Y + + +++ I+ W P KS++D
Sbjct: 327 HRHQSYVARTQTWDEFPNGRWTDSRSPAFGELDVYG-IGLKGTNEQNIKLWGEP-KSIKD 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ F F KL PWSE + ET II + L +N +GFLTINSQPA+NG S P
Sbjct: 385 LSSIFVRFLEAKLDRLPWSE-SSITEETDIIKQDLIDLNNRGFLTINSQPAINGASSSHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG GYVYQKAYLE E +D ++ + + LTY A NK G K+N + N
Sbjct: 444 VYGWGPKNGYVYQKAYLELLIPPEIIDEVITRIQKNADLTYYATNKNGELKTNTSDSP-N 502
Query: 545 AVTWGVF 565
AVTWG+F
Sbjct: 503 AVTWGIF 509
[73][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 155 bits (391), Expect = 3e-36
Identities = 83/187 (44%), Positives = 116/187 (62%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
+R +SY++RT WD+YP+GRW DS +P++G L Y + + +++ I+ W P KS+++
Sbjct: 327 HRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYG-IGLKGTNEQNIKLWGEP-KSLKE 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ E F F G L PWSE + ET+II L +N KGFLTINSQPA++G S P
Sbjct: 385 LSEIFIRFLNGSLDRLPWSE-GAVTEETEIIKSDLLDLNRKGFLTINSQPAIDGMPSSHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG GYVYQKAYLE S +D ++ + + LTY VNK+G K+N + N
Sbjct: 444 IYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNSDLTYYCVNKKGELKTNTTDSP-N 502
Query: 545 AVTWGVF 565
AVTWG+F
Sbjct: 503 AVTWGIF 509
[74][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 155 bits (391), Expect = 3e-36
Identities = 83/187 (44%), Positives = 116/187 (62%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
+R +SY++RT WD+YP+GRW DS +P++G L Y + + +++ I+ W P KS+++
Sbjct: 327 HRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYG-IGLKGTNEQNIKLWGEP-KSLKE 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ E F F G L PWSE + ET+II L +N KGFLTINSQPA++G S P
Sbjct: 385 LSEIFIRFLNGSLDRLPWSE-GAVTEETEIIKSDLLDLNRKGFLTINSQPAIDGMPSSHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG GYVYQKAYLE S +D ++ + + LTY VNK+G K+N + N
Sbjct: 444 IYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNSDLTYYCVNKKGELKTNTTDSP-N 502
Query: 545 AVTWGVF 565
AVTWG+F
Sbjct: 503 AVTWGIF 509
[75][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 154 bits (390), Expect = 3e-36
Identities = 78/176 (44%), Positives = 112/176 (63%), Gaps = 10/176 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKS 175
A+RPKSYI RT WD++P+GRWG+S +P++G L DY +++ ++ ++L++ W L S
Sbjct: 362 ASRPKSYIHRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGQELSS 421
Query: 176 VEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F + G+ N PW++ D L PET ++ L+K+N +G LTINSQP
Sbjct: 422 EESVFEVFTYYISGEPNPNGHKVTCLPWND-DPLAPETNLLKSELQKVNKRGILTINSQP 480
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD-RPFLTYMAVN 499
VNG+ S P VGWG GYV+QKAYLEFF S E + AL++ K P + Y VN
Sbjct: 481 NVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEMVTALIKVLKRYEPRVNYHIVN 536
[76][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 154 bits (390), Expect = 3e-36
Identities = 86/190 (45%), Positives = 110/190 (57%), Gaps = 2/190 (1%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQF--MRPRAKDKKLIEEWAVPLKSV 178
NR KSY+ RT WD++P+GRWGDS +P++G L Y + +++K E KSV
Sbjct: 322 NRNKSYVMRTQDWDEFPNGRWGDSRSPAFGELDAYGIGLLGTNEQNRKKFGE----PKSV 377
Query: 179 EDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSD 358
+DI F + ++ T PWSE L E + I + L +N +G +TINSQPAVNG +S
Sbjct: 378 KDIATLFVRYVQKEVDTLPWSE-SPLDAEAEQIRDDLIDLNLRGLITINSQPAVNGVRST 436
Query: 359 SPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTD 538
P GWG P GYVYQKAYLE + L E+ D P LTY AV K G +N
Sbjct: 437 HPIHGWGPPNGYVYQKAYLELLVHPAIFEQLKERIHDHPDLTYYAVTKSGNLHTNATYEG 496
Query: 539 VNAVTWGVFP 568
NAVTWGVFP
Sbjct: 497 PNAVTWGVFP 506
[77][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 154 bits (390), Expect = 3e-36
Identities = 81/197 (41%), Positives = 115/197 (58%), Gaps = 9/197 (4%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR SYI+RT WD++P+GRWGDS +P++G + R KK + W P ++++D
Sbjct: 331 NRKYSYITRTATWDEFPNGRWGDSRSPAFGDIDLCASELLRQSPKKAYDLWGTP-QTLKD 389
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ + G+L++ PWS+ + +T ++ E+L +N KGFLT+NSQPA+N KS
Sbjct: 390 FSDIIVSYLQGELKSLPWSD-GPIGEDTSVMVENLINLNHKGFLTMNSQPALNAVKSSEK 448
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALV---------EKTKDRPFLTYMAVNKEGVWK 517
GWG GYVYQK YLEFFC K+ L L+ E ++Y AV+K G
Sbjct: 449 VYGWGPKNGYVYQKQYLEFFCPKDLLPKLLHTIDSYNKSEGDASSSIISYYAVDKNGNLS 508
Query: 518 SNVGQTDVNAVTWGVFP 568
+N D+NAVTWGVFP
Sbjct: 509 TNCKDDDINAVTWGVFP 525
[78][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 154 bits (388), Expect = 6e-36
Identities = 80/197 (40%), Positives = 117/197 (59%), Gaps = 9/197 (4%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
+R SYISRT WD++P+GRWGDS +P++G + R KK E W +P +S+ D
Sbjct: 331 HRKYSYISRTATWDEFPNGRWGDSRSPAFGDIDLCASELLRQSPKKAFELWGLP-QSLAD 389
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ + G L++ PWS+ + +T++I + L +N GF T+NSQPA+N KS
Sbjct: 390 LSGIIINYLKGDLKSLPWSD-GPVGDDTRVIVDDLIYLNQHGFFTMNSQPALNAVKSSEK 448
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD---------RPFLTYMAVNKEGVWK 517
GWG GYVYQK YLEFFC K+ + L+++ ++ F++Y AV+K+G
Sbjct: 449 VFGWGPKNGYVYQKQYLEFFCHKDVVSKLLDQVEEFNIKGAESSSAFISYYAVDKDGNLS 508
Query: 518 SNVGQTDVNAVTWGVFP 568
+N D+NAVTWGVFP
Sbjct: 509 TNCKDDDINAVTWGVFP 525
[79][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 153 bits (387), Expect = 8e-36
Identities = 82/187 (43%), Positives = 114/187 (60%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
+R +SY++RT WD++P+GRW DS +P++G L Y + + +++ I+ W P KS++D
Sbjct: 327 HRHQSYVARTQTWDEFPNGRWTDSRSPAFGELDVYG-IGLKGTNEQNIKLWGEP-KSIKD 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ F F G L PWSE + ET I + L +N +GFLTINSQPAVNG S P
Sbjct: 385 LSAIFIRFLEGGLDRLPWSE-SPITEETDDIKQDLIDLNNRGFLTINSQPAVNGMSSSHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG GYVYQKAYLE E + ++ + + P LTY A+NK G K+N + N
Sbjct: 444 VYGWGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNPDLTYYAINKNGELKTNTSDSP-N 502
Query: 545 AVTWGVF 565
AVTWG+F
Sbjct: 503 AVTWGIF 509
[80][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 153 bits (387), Expect = 8e-36
Identities = 81/187 (43%), Positives = 116/187 (62%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
+R +SY++RT WD+YP+GRW DS +P++G L Y + + +++ I+ W P KS+++
Sbjct: 327 HRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYG-IGLKGTNEQNIQLWGKP-KSLKE 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ E F F GKL PWSE + ET II L +N++GFLTINSQPA++G S P
Sbjct: 385 LSEIFIRFLNGKLDRLPWSE-GAVTEETDIIKRDLLDLNSRGFLTINSQPAIDGVHSSHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG GYVYQKAYLE S ++ ++ + + LTY VNK G ++N + N
Sbjct: 444 VYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVNKTGELRTNTSDSP-N 502
Query: 545 AVTWGVF 565
AVTWG+F
Sbjct: 503 AVTWGIF 509
[81][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 153 bits (386), Expect = 1e-35
Identities = 85/199 (42%), Positives = 116/199 (58%), Gaps = 11/199 (5%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVP--LKSV 178
NR SYISRT WD++P+GRWGDS +P++G + + R KK + W P LK
Sbjct: 331 NRKYSYISRTSTWDEFPNGRWGDSRSPAFGDIDLFATDLLRQSPKKAFDLWGHPGTLKQF 390
Query: 179 EDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSD 358
DI F GKL + PWS+ + +++II ++L +N KGF T+NSQP++N KS+
Sbjct: 391 SDIIISF---LSGKLNSLPWSD-SAIGQDSEIIVDNLIALNKKGFFTLNSQPSLNAIKSN 446
Query: 359 SPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEK---------TKDRPFLTYMAVNKEGV 511
GWG GYVYQK YLEFF K+ + AL+ + + LTY AV+++G
Sbjct: 447 DKVYGWGPKNGYVYQKQYLEFFVHKDIIPALLHQIDNYNRGQGDSNSSVLTYYAVDQKGK 506
Query: 512 WKSNVGQTDVNAVTWGVFP 568
SN D+NAVTWGVFP
Sbjct: 507 LFSNTKDDDINAVTWGVFP 525
[82][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 153 bits (386), Expect = 1e-35
Identities = 81/187 (43%), Positives = 116/187 (62%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
+R +SY++RT WD+YP+GRW DS +P++G L Y + + +++ I+ W P KS+++
Sbjct: 327 HRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYG-IGLKGTNEQNIQLWGKP-KSLKE 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ E F F GKL PWSE + ET II L +N++GFLTINSQPA++G S P
Sbjct: 385 LSEIFIHFLNGKLDRLPWSE-GAVTEETDIIKRDLLDLNSRGFLTINSQPAIDGVHSSHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG GYVYQKAYLE S ++ ++ + + LTY VNK G ++N + N
Sbjct: 444 VYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVNKTGELRTNTSDSP-N 502
Query: 545 AVTWGVF 565
AVTWG+F
Sbjct: 503 AVTWGIF 509
[83][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 153 bits (386), Expect = 1e-35
Identities = 85/199 (42%), Positives = 116/199 (58%), Gaps = 11/199 (5%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVP--LKSV 178
NR SYISRT WD++P+GRWGDS +P++G + + R KK + W P LK
Sbjct: 331 NRKYSYISRTSTWDEFPNGRWGDSRSPAFGDIDLFATDLLRQSPKKAFDLWGHPGTLKQF 390
Query: 179 EDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSD 358
DI F GKL + PWS+ + +++II ++L +N KGF T+NSQP++N KS+
Sbjct: 391 SDIIISF---LSGKLNSLPWSD-SAIGQDSEIIVDNLIALNKKGFFTLNSQPSLNAIKSN 446
Query: 359 SPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEK---------TKDRPFLTYMAVNKEGV 511
GWG GYVYQK YLEFF K+ + AL+ + + LTY AV+++G
Sbjct: 447 DKVYGWGPKNGYVYQKQYLEFFVHKDIIPALLHQIDNYNRGQGDSNSSVLTYYAVDQKGK 506
Query: 512 WKSNVGQTDVNAVTWGVFP 568
SN D+NAVTWGVFP
Sbjct: 507 LFSNTKDDDINAVTWGVFP 525
[84][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 153 bits (386), Expect = 1e-35
Identities = 79/188 (42%), Positives = 111/188 (59%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR KSY++RT WD++P+GRWGDS +P++G L Y ++ ++W P + D
Sbjct: 327 NRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGTNEQNR-QKWGEPT-CIRD 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
I F + ++ PWSE + E +I ++L +N +G +T+NSQPAVNG KS P
Sbjct: 385 IANLFVRYLKKEIEYLPWSEAP-VAEEADLIKDYLLDLNKRGLITVNSQPAVNGVKSTHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG GYVYQKAYLE S E + ++ ++ P LTY AV K G+ ++N N
Sbjct: 444 VHGWGPSKGYVYQKAYLELLVSPEVYPEIKKRIENHPDLTYHAVTKSGMLETNAPSDAPN 503
Query: 545 AVTWGVFP 568
AVTWGVFP
Sbjct: 504 AVTWGVFP 511
[85][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 152 bits (385), Expect = 1e-35
Identities = 80/197 (40%), Positives = 116/197 (58%), Gaps = 9/197 (4%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
+R SYISRT WD++P+GRWGDS +P++G + R KK E W +P +S+ +
Sbjct: 331 HRKYSYISRTATWDEFPNGRWGDSRSPAFGDIDLCASELLRQSPKKAFELWGLP-QSLAE 389
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ + G L++ PWS+ + +TK+I + L +N GF T+NSQPA+N KS
Sbjct: 390 LSGIIINYLKGDLKSLPWSD-GPVGDDTKVIVDDLIYLNQHGFFTMNSQPALNAVKSSEK 448
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD---------RPFLTYMAVNKEGVWK 517
GWG GYVYQK YLEFFC K+ + L++ ++ F++Y AV+K+G
Sbjct: 449 VFGWGPKNGYVYQKQYLEFFCHKDVVSKLLDHVEEFNVKGAESSSAFISYYAVDKDGNLS 508
Query: 518 SNVGQTDVNAVTWGVFP 568
+N D+NAVTWGVFP
Sbjct: 509 TNCKDDDINAVTWGVFP 525
[86][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 152 bits (385), Expect = 1e-35
Identities = 82/187 (43%), Positives = 113/187 (60%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
+R +SY++RT WD++P+GRW DS +P++G L Y + + +++ I+ W P KS++D
Sbjct: 327 HRHQSYVARTQTWDEFPNGRWTDSRSPAFGELDVYG-IGLKGTNEQNIKLWGEP-KSIKD 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ F F G L PWSE + ET I L +N +GFLTINSQPAVNG S P
Sbjct: 385 LSAIFIRFLEGGLDRLPWSE-SPITEETDDIKHDLIDLNNRGFLTINSQPAVNGMSSSHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG GYVYQKAYLE E + ++ + + P LTY A+NK G K+N + N
Sbjct: 444 VYGWGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNPDLTYYAINKNGELKTNTSDSP-N 502
Query: 545 AVTWGVF 565
AVTWG+F
Sbjct: 503 AVTWGIF 509
[87][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 152 bits (385), Expect = 1e-35
Identities = 81/187 (43%), Positives = 116/187 (62%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
+R +SY++RT WD+YP+GRW DS +P++G L Y + + +++ I+ W P KS+++
Sbjct: 327 HRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYG-IGLKGTNEQNIQLWGKP-KSLKE 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ E F F GKL PWSE + ET II L +N++GFLTINSQPA++G S P
Sbjct: 385 LSEIFIRFLNGKLDRLPWSE-GAVTEETDIIKRDLLDLNSRGFLTINSQPAIDGVHSSHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG GYVYQKAYLE S ++ ++ + + LTY VNK G ++N + N
Sbjct: 444 VYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVNKTGELRTNTTDSP-N 502
Query: 545 AVTWGVF 565
AVTWG+F
Sbjct: 503 AVTWGIF 509
[88][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 152 bits (385), Expect = 1e-35
Identities = 80/187 (42%), Positives = 116/187 (62%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
+R +SY++RT WD+YP+GRW DS +P++G L Y + + +++ I+ W P KS+++
Sbjct: 327 HRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYG-VGLKGTNEQNIKLWGEP-KSLKE 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ E F F G L PWSE + ET ++ L +N +GFLTINSQPA++G S P
Sbjct: 385 LSEIFVRFLNGNLDRLPWSE-GAVTEETDVLKLDLLDLNRRGFLTINSQPAIDGMPSSHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG GYVYQKAYLE S +D ++ + + P LTY VNK+G ++N + N
Sbjct: 444 VYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKKGELRTNTTDSP-N 502
Query: 545 AVTWGVF 565
AVTWG+F
Sbjct: 503 AVTWGIF 509
[89][TOP]
>UniRef100_UPI000151BABB hypothetical protein PGUG_04648 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151BABB
Length = 355
Score = 152 bits (384), Expect = 2e-35
Identities = 81/196 (41%), Positives = 117/196 (59%), Gaps = 8/196 (4%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR SYISRT WD++P+GRWGDS +P++G + + R K+ + W P +S +D
Sbjct: 71 NRKYSYISRTSTWDEFPNGRWGDSRSPAFGDIDLFAADLLRQSPKRAFDLWGCP-QSFKD 129
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ + L++ PWS+ + +T II + L +N +GFLT+NSQP++N KS+
Sbjct: 130 LSNLVVSYLKNDLKSLPWSD-GPIGEDTAIIVDKLISLNQRGFLTMNSQPSLNCVKSNDK 188
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKE---KLDALVEKTKDR-----PFLTYMAVNKEGVWKS 520
GWG GYV+QK YLEFFC ++ KL +EK ++ FLTY A +K G +
Sbjct: 189 VYGWGPKNGYVFQKQYLEFFCHRDIFPKLLESIEKFNEKGGESCSFLTYYAADKNGELNT 248
Query: 521 NVGQTDVNAVTWGVFP 568
N + D+NAVTWGVFP
Sbjct: 249 NTKEDDINAVTWGVFP 264
[90][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 152 bits (384), Expect = 2e-35
Identities = 81/187 (43%), Positives = 114/187 (60%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR SYI+RT WD++P+GRW DS +P++G L Y + + +++ I+ W P KS++D
Sbjct: 327 NRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDSYG-IGLKGTNEQNIQLWGEP-KSIKD 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ F + GKL PWS+ + E K I +L ++N +G LTINSQPAVNG KS P
Sbjct: 385 LSRLFVRYLEGKLSRLPWSDTP-ISSEAKAIKPNLIELNNRGILTINSQPAVNGAKSSHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG G+VYQKAYLE LD L+ + + LTY AV+K G ++N + N
Sbjct: 444 VYGWGPKNGFVYQKAYLELLIPPYLLDELIARIEGNEDLTYHAVSKNGELRTNTHDSP-N 502
Query: 545 AVTWGVF 565
A+TWG+F
Sbjct: 503 ALTWGIF 509
[91][TOP]
>UniRef100_A5DMZ7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DMZ7_PICGU
Length = 355
Score = 152 bits (384), Expect = 2e-35
Identities = 81/196 (41%), Positives = 117/196 (59%), Gaps = 8/196 (4%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR SYISRT WD++P+GRWGDS +P++G + + R K+ + W P +S +D
Sbjct: 71 NRKYSYISRTSTWDEFPNGRWGDSRSPAFGDIDLFAADLLRQSPKRAFDLWGCP-QSFKD 129
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ + L++ PWS+ + +T II + L +N +GFLT+NSQP++N KS+
Sbjct: 130 LSNLVVSYLKNDLKSLPWSD-GPIGEDTAIIVDKLISLNQRGFLTMNSQPSLNCVKSNDK 188
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKE---KLDALVEKTKDR-----PFLTYMAVNKEGVWKS 520
GWG GYV+QK YLEFFC ++ KL +EK ++ FLTY A +K G +
Sbjct: 189 VYGWGPKNGYVFQKQYLEFFCHRDIFPKLLESIEKFNEKGGESCSFLTYYAADKNGELNT 248
Query: 521 NVGQTDVNAVTWGVFP 568
N + D+NAVTWGVFP
Sbjct: 249 NTKEDDINAVTWGVFP 264
[92][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 152 bits (384), Expect = 2e-35
Identities = 82/187 (43%), Positives = 115/187 (61%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR SYI+RT WD++P+GRW DS +P++G L Y + + +++ I+ W P KS+ D
Sbjct: 327 NRNSSYIARTQIWDEFPNGRWTDSRSPAFGELDAYG-IGLKGTNEQNIKLWGEP-KSIRD 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
I + F + GKL PWS+ + E I E+L ++N +G LT+NSQPAVNG +S P
Sbjct: 385 ISQIFVRYVEGKLERLPWSD-SPISAEANAIKENLIELNGRGLLTVNSQPAVNGVRSSHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG G+VYQKAYLE F LD L+ + + LTY AV KEG ++N + N
Sbjct: 444 VYGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNDDLTYHAVAKEGELRTNT-RDSPN 502
Query: 545 AVTWGVF 565
A+TWG+F
Sbjct: 503 ALTWGIF 509
[93][TOP]
>UniRef100_Q8MQE7 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis elegans
RepID=Q8MQE7_CAEEL
Length = 642
Score = 152 bits (383), Expect = 2e-35
Identities = 87/202 (43%), Positives = 121/202 (59%), Gaps = 15/202 (7%)
Frame = +2
Query: 8 RPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMR---PRAKDKKLIEEWAVPLKSV 178
RP+SYI+RT WDQ+P+GRWG+S +P++G ++ Y R D +L + ++S
Sbjct: 363 RPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLSNLTTVRNADDRLAM-FGANIESF 421
Query: 179 EDIYERFRLFCLG-------KLRTNPWSELD-GLQPETKIINEHLEKINTKGFLTINSQP 334
ED+ F + K+ PW+E + G+QPET +I+E L N G LT+NSQP
Sbjct: 422 EDVKRVFINYITQAPNADGVKVTVLPWTEAETGVQPETSLISEQLVWCNENGILTVNSQP 481
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF---LTYMAVNKE 505
+VNG S P VGWG PGGY YQKAYLE F + E D L++ +R F + Y A+NK+
Sbjct: 482 SVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSDKLIQ-IIEREFPVRVNYHAINKD 540
Query: 506 GVW-KSNVGQTDVNAVTWGVFP 568
+ K+N +T AVTWGVFP
Sbjct: 541 STFDKTNSEETTPIAVTWGVFP 562
[94][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 152 bits (383), Expect = 2e-35
Identities = 79/188 (42%), Positives = 112/188 (59%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR KSY+ RT WD++P+GRWGDS +P++G L Y + ++W P K+V+D
Sbjct: 327 NRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGTNEANR-KKWGEP-KTVQD 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
I + F + ++ + PWSE L E I + L ++N +G LT+NSQPAVNG KS
Sbjct: 385 IAQLFVRYLRNEIDSLPWSE-SPLTSEADEIRDDLVELNKRGLLTVNSQPAVNGVKSSHA 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG GYVYQK+YLE + + ++ + ++ P LT+ AV K+G +SN N
Sbjct: 444 VHGWGPSNGYVYQKSYLELLVHPDVFNDMIGRIENHPDLTFYAVTKDGELRSNAPSDCPN 503
Query: 545 AVTWGVFP 568
AVTWGVFP
Sbjct: 504 AVTWGVFP 511
[95][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 152 bits (383), Expect = 2e-35
Identities = 81/187 (43%), Positives = 115/187 (61%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
+R +SY++RT WD+YP+GRW DS +P++G L Y + + +++ I+ W P KS+++
Sbjct: 313 HRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYG-IGLKGTNEQNIKLWGEP-KSLKE 370
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ E F F G L PWSE + ET +I L +N +GFLTINSQPA++G S P
Sbjct: 371 LSEIFVRFLNGNLDRLPWSE-GAVTEETDVIKLDLLDLNRRGFLTINSQPAIDGMPSSHP 429
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG GYVYQKAYLE S +D ++ + + P LTY VNK G ++N + N
Sbjct: 430 VYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKIGELRTNTTDSP-N 488
Query: 545 AVTWGVF 565
AVTWG+F
Sbjct: 489 AVTWGIF 495
[96][TOP]
>UniRef100_Q17693 Probable methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis
elegans RepID=MTHR_CAEEL
Length = 663
Score = 152 bits (383), Expect = 2e-35
Identities = 87/202 (43%), Positives = 121/202 (59%), Gaps = 15/202 (7%)
Frame = +2
Query: 8 RPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMR---PRAKDKKLIEEWAVPLKSV 178
RP+SYI+RT WDQ+P+GRWG+S +P++G ++ Y R D +L + ++S
Sbjct: 384 RPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLSNLTTVRNADDRLAM-FGANIESF 442
Query: 179 EDIYERFRLFCLG-------KLRTNPWSELD-GLQPETKIINEHLEKINTKGFLTINSQP 334
ED+ F + K+ PW+E + G+QPET +I+E L N G LT+NSQP
Sbjct: 443 EDVKRVFINYITQAPNADGVKVTVLPWTEAETGVQPETSLISEQLVWCNENGILTVNSQP 502
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF---LTYMAVNKE 505
+VNG S P VGWG PGGY YQKAYLE F + E D L++ +R F + Y A+NK+
Sbjct: 503 SVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSDKLIQ-IIEREFPVRVNYHAINKD 561
Query: 506 GVW-KSNVGQTDVNAVTWGVFP 568
+ K+N +T AVTWGVFP
Sbjct: 562 STFDKTNSEETTPIAVTWGVFP 583
[97][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 151 bits (382), Expect = 3e-35
Identities = 80/188 (42%), Positives = 110/188 (58%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR KSY++RT WD++P+GRWGDS +P++G L Y + ++ ++W P S++D
Sbjct: 327 NRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDAYGVGLTGSNEQNR-KKWGEPT-SIKD 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
I F + ++ PWSE + E +I + L ++N +G +T+NSQPAVNG KS P
Sbjct: 385 IANLFVRYLNKEIEYLPWSEAP-VAEEADLIKDDLIELNNRGLITVNSQPAVNGVKSTHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG GYVYQKAYLE S E + + + P LTY AV K G +N N
Sbjct: 444 IHGWGPANGYVYQKAYLEMLISPELFPQIKSRIESHPDLTYHAVTKSGNLHTNAQFEGPN 503
Query: 545 AVTWGVFP 568
AVTWGVFP
Sbjct: 504 AVTWGVFP 511
[98][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6H337_AJECH
Length = 524
Score = 151 bits (381), Expect = 4e-35
Identities = 80/187 (42%), Positives = 115/187 (61%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
+R +SY++RT WD+YP+GRW DS +P++G L Y + + +++ I+ W P KS+++
Sbjct: 218 HRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYG-IGLKGTNEQNIKLWGEP-KSLKE 275
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ E F F G L PWSE + ET ++ L +N +GFLTINSQPA++G S P
Sbjct: 276 LSEIFVRFLNGNLDRLPWSE-GAVTEETDVLKLDLLDLNRRGFLTINSQPAIDGMPSSHP 334
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG GYVYQKAYLE S +D ++ + + P LTY VNK G ++N + N
Sbjct: 335 VYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKIGELRTNTTDSP-N 393
Query: 545 AVTWGVF 565
AVTWG+F
Sbjct: 394 AVTWGIF 400
[99][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 150 bits (379), Expect = 7e-35
Identities = 80/187 (42%), Positives = 115/187 (61%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR SYI+RT WD++P+GRW DS +P++G L Y + + +++ I+ W P KS+ D
Sbjct: 327 NRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDAYG-IGLKGTNEQNIKLWGEP-KSIRD 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
I + F + GKL PWS+ + E I ++L ++N++G LT+NSQPAVNG +S P
Sbjct: 385 ITQIFVRYLEGKLDRLPWSD-SPISGEANAIKDNLVQLNSRGLLTVNSQPAVNGVRSSHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG G+VYQKAYLE F LD L+ + + P LTY AV K ++N + N
Sbjct: 444 VFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLTYHAVAKNRELRTNT-RDSPN 502
Query: 545 AVTWGVF 565
A+TWG+F
Sbjct: 503 ALTWGIF 509
[100][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 150 bits (379), Expect = 7e-35
Identities = 80/187 (42%), Positives = 115/187 (61%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR SYI+RT WD++P+GRW DS +P++G L Y + + +++ I+ W P KS+ D
Sbjct: 327 NRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDAYG-IGLKGTNEQNIKLWGEP-KSIRD 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
I + F + GKL PWS+ + E I ++L ++N++G LT+NSQPAVNG +S P
Sbjct: 385 ITQIFVRYLEGKLDRLPWSD-SPISGEANAIKDNLVQLNSRGLLTVNSQPAVNGVRSSHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG G+VYQKAYLE F LD L+ + + P LTY AV K ++N + N
Sbjct: 444 VFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLTYHAVAKNRELRTNT-RDSPN 502
Query: 545 AVTWGVF 565
A+TWG+F
Sbjct: 503 ALTWGIF 509
[101][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 150 bits (378), Expect = 9e-35
Identities = 84/194 (43%), Positives = 111/194 (57%), Gaps = 5/194 (2%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ----FMRPRAKDKKLIEEWAVPL 169
+NRPKSY+ RT WD++P+GRWGDS +P++G L+D F +D++ +
Sbjct: 323 SNRPKSYVMRTDDWDEFPNGRWGDSTSPAFGELSDLSHFCSFTLGSDEDRRAMLGHNPQA 382
Query: 170 KSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGE 349
+S D+YE F + G + PW E LQPE+ +I L K+N GFLT+NSQP V+G
Sbjct: 383 ES--DVYEVFARYVEGSVPHIPWCETP-LQPESFLIQPQLAKLNRYGFLTVNSQPPVDGL 439
Query: 350 KSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEG-VWKSNV 526
S GWGG GG VYQKAY E F S K + L + D P L AVN G + V
Sbjct: 440 PSCHKVFGWGGKGGRVYQKAYFECFVSPSKANRLTQMVTDHPSLNMYAVNNAGQELRVGV 499
Query: 527 GQTDVNAVTWGVFP 568
+ V A+TWGVFP
Sbjct: 500 EEGGVTALTWGVFP 513
[102][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S5W8_NEMVE
Length = 619
Score = 150 bits (378), Expect = 9e-35
Identities = 83/199 (41%), Positives = 111/199 (55%), Gaps = 10/199 (5%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRA--KDKKLIEEWAVPLKS 175
A+RP+SY+ RT W+ P+GRWG+S + S+G L DY KD +L+ W L S
Sbjct: 342 ASRPRSYLIRTSNWEDMPNGRWGNSSSASFGDLKDYHLFLTGTSRKDSELLSMWGRELNS 401
Query: 176 VEDIYERFRLFCLG-------KLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
+D+++ F + G K+ PWS+ + L PET + E L N G LTINSQP
Sbjct: 402 EQDVFDIFVCYLTGRDNKQGFKVTELPWSDGE-LAPETIPLVEKLVHANQNGILTINSQP 460
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVW 514
++N S+ P GWG PGGYV+QKAYLEFF +E L + KD + + VN G
Sbjct: 461 SLNAVPSEDPNHGWGKPGGYVFQKAYLEFFAREEIALELYHQLKDGTRINFHLVNSSGES 520
Query: 515 K-SNVGQTDVNAVTWGVFP 568
+N NAVTWGVFP
Sbjct: 521 DFTNANMYSPNAVTWGVFP 539
[103][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 150 bits (378), Expect = 9e-35
Identities = 81/199 (40%), Positives = 114/199 (57%), Gaps = 11/199 (5%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVP--LKSV 178
NR SY+SRT WD++P+GRWGDS +P++G + R K+ E W P LK +
Sbjct: 332 NRKYSYVSRTATWDEFPNGRWGDSRSPAFGDIDLCASELLRQSPKRAYELWGTPGSLKEL 391
Query: 179 EDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSD 358
DI + G L++ PWS+ + +TK+I + L ++N +G LT+NSQPA+N KS
Sbjct: 392 SDIVISY---LKGDLKSLPWSD-GSVGDDTKVIVDDLVELNKRGLLTMNSQPALNSIKSS 447
Query: 359 SPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD---------RPFLTYMAVNKEGV 511
GWG GYVYQK YLEFFC K+ + L++ D ++Y AV+ +G
Sbjct: 448 EKIFGWGPKNGYVYQKQYLEFFCHKDIIVKLLQTIDDYNNNQGDASSAIISYYAVDLKGN 507
Query: 512 WKSNVGQTDVNAVTWGVFP 568
+N D+NAVTWGVFP
Sbjct: 508 LTTNCNDDDINAVTWGVFP 526
[104][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 150 bits (378), Expect = 9e-35
Identities = 79/187 (42%), Positives = 115/187 (61%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR SYI+RT WD++P+GRW DS +P++G L Y + + +++ I+ W P KS+ D
Sbjct: 327 NRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDAYG-IGLKGTNEQNIKLWGEP-KSIRD 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ + F + GKL PWS+ + E I ++L ++N++G LT+NSQPAVNG +S P
Sbjct: 385 VTQIFVRYLEGKLDRLPWSD-SPISGEANAIKDNLVQLNSRGLLTVNSQPAVNGVRSSHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG G+VYQKAYLE F LD L+ + + P LTY AV K ++N + N
Sbjct: 444 VFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLTYHAVAKNRELRTNT-RDSPN 502
Query: 545 AVTWGVF 565
A+TWG+F
Sbjct: 503 ALTWGIF 509
[105][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 149 bits (377), Expect = 1e-34
Identities = 81/187 (43%), Positives = 113/187 (60%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR SYI+RT WD++P+GRW DS +P++G L Y + + +++ I+ W P S+ D
Sbjct: 327 NRNSSYIARTAIWDEFPNGRWTDSRSPAFGELELYG-VGLKGTNEQNIKLWGEP-NSLRD 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ E F F G L PWS+ + PET I + L ++N +GF TINSQPAVNG KS P
Sbjct: 385 LAEVFVRFLEGNLDRLPWSD-SPITPETSAIKDALVELNRRGFFTINSQPAVNGVKSSHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG G+VYQKAYLE +D L+ + + LTY AV K+G ++N + N
Sbjct: 444 VFGWGPKNGFVYQKAYLELLVPPYVIDELIARIEANEDLTYHAVTKKGELRTNT-RDSPN 502
Query: 545 AVTWGVF 565
A+TWG+F
Sbjct: 503 ALTWGIF 509
[106][TOP]
>UniRef100_UPI0000123E6B Hypothetical protein CBG12960 n=1 Tax=Caenorhabditis briggsae AF16
RepID=UPI0000123E6B
Length = 662
Score = 147 bits (371), Expect = 6e-34
Identities = 84/201 (41%), Positives = 122/201 (60%), Gaps = 14/201 (6%)
Frame = +2
Query: 8 RPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRP---RAKDKKLIEEWAVPLKSV 178
RP+SYI+RT WDQ+P+GRWG+S +P++G ++ Y R D +L + ++S+
Sbjct: 385 RPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLSNLTTLRNGDDRL-SMFGENIESI 443
Query: 179 EDIYERFRLFCLG-------KLRTNPWSELD-GLQPETKIINEHLEKINTKGFLTINSQP 334
ED+ F + K+ PW+E + G+QPET +I+E L N G LT+NSQP
Sbjct: 444 EDVKRVFINYITQTPNVSGKKVTVLPWTEAETGVQPETSLISEQLVWCNENGILTVNSQP 503
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVE-KTKDRPF-LTYMAVNKEG 508
+VNG S P VGWG PGGY YQKAYLE F + E + L++ ++ P + Y A++K+
Sbjct: 504 SVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSEKLIDIIEREYPVRVNYHAIDKDS 563
Query: 509 VW-KSNVGQTDVNAVTWGVFP 568
+ K+N +T AVTWGVFP
Sbjct: 564 SFDKTNSEETTPIAVTWGVFP 584
[107][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 146 bits (369), Expect = 1e-33
Identities = 78/197 (39%), Positives = 114/197 (57%), Gaps = 9/197 (4%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR SY++RT WD++P+GRWGDS +P++G + R K+ E W +P +++ D
Sbjct: 331 NRKYSYVTRTATWDEFPNGRWGDSRSPAFGDIDLCASELLRQSPKRAQELWGLP-QTISD 389
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
I + G+L + PW + + +T II +HL ++N +T+NSQP++N +S
Sbjct: 390 ITGLVISYLKGQLNSLPWFD-GAIGEDTNIILDHLIELNENSLITLNSQPSLNSVRSSDK 448
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKE----KLDALVEKTKDR-----PFLTYMAVNKEGVWK 517
GWG GYVYQK YLEFFC K+ LD + + K++ ++Y AVNK G
Sbjct: 449 VFGWGPKNGYVYQKQYLEFFCHKDVVARLLDHIDQYNKNQGDSTSAVISYYAVNKNGNLI 508
Query: 518 SNVGQTDVNAVTWGVFP 568
SN D+NAVTWGVFP
Sbjct: 509 SNCQDDDINAVTWGVFP 525
[108][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 146 bits (368), Expect = 1e-33
Identities = 81/187 (43%), Positives = 109/187 (58%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR SYI+RT WD++P+GRW DS +P++G L Y + + +++ I+ W P KS+ D
Sbjct: 327 NRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDSYG-IGLKGTNEQNIKLWGEP-KSLRD 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ F F GKL PWS+ + E I L +N KG TINSQPAVNG KS P
Sbjct: 385 LTHIFVNFLEGKLARLPWSDTP-ITTEANAIKTSLIDLNQKGLFTINSQPAVNGVKSSHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG GYVYQKAYLE +D L+ + + LTY AV+K G ++N + N
Sbjct: 444 VYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNGDLTYHAVSKTGELRTNT-RDSPN 502
Query: 545 AVTWGVF 565
A+TWG+F
Sbjct: 503 ALTWGIF 509
[109][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 145 bits (367), Expect = 2e-33
Identities = 78/187 (41%), Positives = 111/187 (59%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR SYI+RT WD++P+GRW DS +P++G L Y + + +++ I+ W P KS+ D
Sbjct: 327 NRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDSYG-IGLKGTNEQNIKLWGEP-KSIRD 384
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ F F G+L PWS+ + E I + L ++N +G TINSQPAVNG +S P
Sbjct: 385 LAHIFVKFMQGELARLPWSDTP-ISGEANAIKDKLIELNKRGLFTINSQPAVNGARSSHP 443
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVN 544
GWG G+VYQKAYLE LD L+ + + LTY AV+K G ++N + N
Sbjct: 444 VYGWGPKNGFVYQKAYLELLVPPYLLDELIARIEKNEDLTYHAVSKTGELRTNT-RDSPN 502
Query: 545 AVTWGVF 565
A+TWG+F
Sbjct: 503 ALTWGIF 509
[110][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
RepID=A8PV87_BRUMA
Length = 656
Score = 144 bits (364), Expect = 4e-33
Identities = 81/199 (40%), Positives = 113/199 (56%), Gaps = 12/199 (6%)
Frame = +2
Query: 8 RPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQ--FMRPRAKDKKLIEEWAVPLKSVE 181
RPKSY+ RT WD++P+GRWG+S +P++ L DY +++ + + + + L+++
Sbjct: 383 RPKSYVFRTREWDEFPNGRWGNSSSPAFNDLKDYYLFYLKGQPTRDEQLRMYGERLETLA 442
Query: 182 DIYERFRLFCLGKLRTN-------PWSEL-DGLQPETKIINEHLEKINTKGFLTINSQPA 337
DI + F F + N PW+E DG++ ET +I + L N+ GFLTINSQP+
Sbjct: 443 DIQKVFVNFITQNINENGVKVSQLPWNEQHDGIRAETSLIKDQLLWCNSNGFLTINSQPS 502
Query: 338 VNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGV-- 511
+NG S P VGWG PGGY YQKAYLEFF S+ + L L VN +
Sbjct: 503 INGAPSTDPFVGWGKPGGYCYQKAYLEFFTSQANAEVLWSLLPSYSRLNCHIVNHDATID 562
Query: 512 WKSNVGQTDVNAVTWGVFP 568
W +N T AVTWGVFP
Sbjct: 563 W-TNTETTMPIAVTWGVFP 580
[111][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 144 bits (364), Expect = 4e-33
Identities = 77/197 (39%), Positives = 114/197 (57%), Gaps = 8/197 (4%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
+NR +YISRT WD++P+GRWGDS +P++G + R K+ +E W P +S++
Sbjct: 323 SNRKFTYISRTSNWDEFPNGRWGDSRSPAFGEVDLCDGDLIRHSPKRAVELWGKP-QSID 381
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
D+ + F + G L + PWS+ + E ++ + L +N +G LTINSQP VNG S+
Sbjct: 382 DVIDLFVRYLQGNLSSLPWSDGE-TSKEINVLLDDLLALNRQGILTINSQPCVNGLPSNH 440
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDR--------PFLTYMAVNKEGVWK 517
GWG G+VYQK YLEFF + L L+ ++ LT+ AVN +G
Sbjct: 441 NVHGWGPSNGFVYQKQYLEFFIPAKFLTKLISNIEELNKSYSSNFNTLTFYAVNAQGELI 500
Query: 518 SNVGQTDVNAVTWGVFP 568
+N + D+NAVTWG+FP
Sbjct: 501 TNSKEDDINAVTWGIFP 517
[112][TOP]
>UniRef100_A8XGR9 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis briggsae
RepID=A8XGR9_CAEBR
Length = 724
Score = 143 bits (361), Expect = 8e-33
Identities = 83/211 (39%), Positives = 123/211 (58%), Gaps = 24/211 (11%)
Frame = +2
Query: 8 RPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRP---RAKDKKLIEEWAVPLKSV 178
RP+SYI+RT WDQ+P+GRWG+S +P++G ++ Y R D +L + ++S+
Sbjct: 435 RPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLSNLTTLRNGDDRL-SMFGENIESI 493
Query: 179 EDIYERFRLFCLG-------KLRTNPWSELD-GLQPETKIINEHLEKINTKGFLTINSQP 334
ED+ F + K+ PW+E + G+QPET +I+E L N G LT+NSQP
Sbjct: 494 EDVKRVFINYITQTPNVSGKKVTVLPWTEAETGVQPETSLISEQLVWCNENGILTVNSQP 553
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVE-KTKDRPF-LTYMAVNKE- 505
+VNG S P VGWG PGGY YQKAYLE F + E + L++ ++ P + Y A++K+
Sbjct: 554 SVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSEKLIDIIEREYPVRVNYHAIDKDV 613
Query: 506 ----------GVWKSNVGQTDVNAVTWGVFP 568
++++N +T AVTWGVFP
Sbjct: 614 SYILNSHDSMQIFRTNSEETTPIAVTWGVFP 644
[113][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 143 bits (361), Expect = 8e-33
Identities = 76/194 (39%), Positives = 113/194 (58%), Gaps = 6/194 (3%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR SYISRT GWD++P+GRWGDS +P++G + R K+ E W P +++ D
Sbjct: 333 NRKYSYISRTSGWDEFPNGRWGDSRSPAFGDIDLSASELLRQSPKRAYELWGCP-QTLND 391
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ + + +++ PWS+ + +T ++ + L +N KG T+NSQPA++ +S+
Sbjct: 392 LSDIIVSYLNNEVKALPWSD-GPIGEDTTVLKDALIALNRKGLFTLNSQPALSAVRSNDK 450
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVE-----KTKDR-PFLTYMAVNKEGVWKSNV 526
GWG G+VYQK YLEF K+KL L++ KD +TY AV+K G +N
Sbjct: 451 LYGWGPKNGFVYQKQYLEFLVRKDKLKELLDIVEKHNAKDTYGLITYYAVDKSGNLHTNS 510
Query: 527 GQTDVNAVTWGVFP 568
D+NAVTWGVFP
Sbjct: 511 KNDDINAVTWGVFP 524
[114][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 143 bits (360), Expect = 1e-32
Identities = 77/190 (40%), Positives = 113/190 (59%), Gaps = 3/190 (1%)
Frame = +2
Query: 8 RPKSYISRTIGW--DQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
RP SY++RT W D++P+GR+GDS +P++G L R KK +E W+ P K++E
Sbjct: 337 RPYSYVARTSQWAMDEFPNGRFGDSSSPAFGDLDLCGSTLIRQSGKKSLELWSTP-KTIE 395
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
D+ + + G+++ PWS+ L E I +HL +N K +TINSQP +NG +S+
Sbjct: 396 DVSQLVISYLTGQIKCLPWSDTS-LDEEIDPILDHLLDLNRKMIITINSQPQINGIRSNH 454
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAV-NKEGVWKSNVGQTD 538
GWG GYVYQK YLEF EK++ L ++ LTY AV NK+ + ++ +
Sbjct: 455 KVHGWGPKDGYVYQKQYLEFLLPNEKVEKLEKQLAGNEMLTYFAVDNKDNLKSNHPDGSK 514
Query: 539 VNAVTWGVFP 568
NAVTWG+FP
Sbjct: 515 ANAVTWGIFP 524
[115][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 140 bits (354), Expect = 5e-32
Identities = 78/190 (41%), Positives = 109/190 (57%), Gaps = 3/190 (1%)
Frame = +2
Query: 8 RPKSYISRTIGW--DQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
RP SY++RT W D++P+GR+GDS +P++G L R K +E W+ P S+
Sbjct: 337 RPYSYVARTSQWAVDEFPNGRFGDSSSPAFGDLDLCGSDLIRQSANKCLELWSTPT-SIN 395
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
D+ + G L+ PWS++ + E I HL ++N +TINSQP VNG +S+
Sbjct: 396 DVAFLVINYLNGNLKCLPWSDIT-INDEINPIKAHLIELNQHSIITINSQPQVNGIRSND 454
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSN-VGQTD 538
GWG GYVYQK YLEF K KL L++ K+ FLTY A++ +G SN +
Sbjct: 455 KIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSK 514
Query: 539 VNAVTWGVFP 568
NAVTWG+FP
Sbjct: 515 SNAVTWGIFP 524
[116][TOP]
>UniRef100_B5VIK4 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VIK4_YEAS6
Length = 411
Score = 140 bits (354), Expect = 5e-32
Identities = 78/190 (41%), Positives = 109/190 (57%), Gaps = 3/190 (1%)
Frame = +2
Query: 8 RPKSYISRTIGW--DQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
RP SY++RT W D++P+GR+GDS +P++G L R K +E W+ P S+
Sbjct: 148 RPYSYVARTSQWAVDEFPNGRFGDSSSPAFGDLDLCGSDLIRQSANKCLELWSTPT-SIN 206
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
D+ + G L+ PWS++ + E I HL ++N +TINSQP VNG +S+
Sbjct: 207 DVAFLVINYLNGNLKCLPWSDIP-INDEINPIKAHLIELNQHSIITINSQPQVNGIRSND 265
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSN-VGQTD 538
GWG GYVYQK YLEF K KL L++ K+ FLTY A++ +G SN +
Sbjct: 266 KIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSK 325
Query: 539 VNAVTWGVFP 568
NAVTWG+FP
Sbjct: 326 SNAVTWGIFP 335
[117][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 140 bits (354), Expect = 5e-32
Identities = 78/190 (41%), Positives = 109/190 (57%), Gaps = 3/190 (1%)
Frame = +2
Query: 8 RPKSYISRTIGW--DQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
RP SY++RT W D++P+GR+GDS +P++G L R K +E W+ P S+
Sbjct: 337 RPYSYVARTSQWAVDEFPNGRFGDSSSPAFGDLDLCGSDLIRQSANKCLELWSTPT-SIN 395
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
D+ + G L+ PWS++ + E I HL ++N +TINSQP VNG +S+
Sbjct: 396 DVAFLVINYLNGNLKCLPWSDIP-INDEINPIKAHLIELNQHSIITINSQPQVNGIRSND 454
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSN-VGQTD 538
GWG GYVYQK YLEF K KL L++ K+ FLTY A++ +G SN +
Sbjct: 455 KIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSK 514
Query: 539 VNAVTWGVFP 568
NAVTWG+FP
Sbjct: 515 SNAVTWGIFP 524
[118][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 140 bits (354), Expect = 5e-32
Identities = 78/190 (41%), Positives = 109/190 (57%), Gaps = 3/190 (1%)
Frame = +2
Query: 8 RPKSYISRTIGW--DQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
RP SY++RT W D++P+GR+GDS +P++G L R K +E W+ P S+
Sbjct: 337 RPYSYVARTSQWAVDEFPNGRFGDSSSPAFGDLDLCGSDLIRQSANKCLELWSTPT-SIN 395
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
D+ + G L+ PWS++ + E I HL ++N +TINSQP VNG +S+
Sbjct: 396 DVAFLVINYLNGNLKCLPWSDIP-INDEINPIKAHLIELNQHSIITINSQPQVNGIRSND 454
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSN-VGQTD 538
GWG GYVYQK YLEF K KL L++ K+ FLTY A++ +G SN +
Sbjct: 455 KIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSK 514
Query: 539 VNAVTWGVFP 568
NAVTWG+FP
Sbjct: 515 SNAVTWGIFP 524
[119][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 139 bits (350), Expect = 2e-31
Identities = 83/190 (43%), Positives = 108/190 (56%), Gaps = 3/190 (1%)
Frame = +2
Query: 8 RPKSYISRTIGW--DQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
RP SY++RT W D++P+GR+GDS +P++G L R KK +E W+ P S+E
Sbjct: 336 RPYSYVARTSQWSVDEFPNGRFGDSSSPAFGDLDLCGASLIRQSGKKSLELWSAP-NSME 394
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
DI + + G+L+ PWS+ L E I L +N K +TINSQP +NG KS
Sbjct: 395 DIAQLVINYLRGELKYLPWSDTS-LNHEVDDILPELVTLNQKLIITINSQPQLNGVKSSH 453
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSN-VGQTD 538
P GWG GYVYQK YLEF KEKL L + + LTY AV+ G +N T
Sbjct: 454 PVHGWGPRDGYVYQKMYLEFLLPKEKLSKLHDCLVNDVMLTYFAVDHNGNLTTNHQDGTR 513
Query: 539 VNAVTWGVFP 568
NAVTWG+FP
Sbjct: 514 ANAVTWGIFP 523
[120][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 137 bits (346), Expect = 4e-31
Identities = 77/188 (40%), Positives = 113/188 (60%), Gaps = 1/188 (0%)
Frame = +2
Query: 8 RPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDI 187
R +S+ISRT WD++P+GRWGDS +P++G D + + D ++ W P +++ D+
Sbjct: 336 RSQSFISRTEQWDEFPNGRWGDSRSPAFGEF-DPKHHGLKQTDAEIRALWGSP-ENIRDL 393
Query: 188 YERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPT 367
F +C KL PWS++ L E+ II + L ++N +G LTINSQP V S P
Sbjct: 394 GNVFAAYCERKLACLPWSDIP-LSGESAIIADKLAELNRQGILTINSQPPVCAAPSTDPL 452
Query: 368 VGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDV-N 544
GWG GYV+QKAYLEFF +++ +L+E + Y + EG ++N G+ DV +
Sbjct: 453 FGWGPAHGYVFQKAYLEFFMHPDQVKSLLEVIPSFKTVQYYITDYEGSLETN-GELDVPS 511
Query: 545 AVTWGVFP 568
AVTWGVFP
Sbjct: 512 AVTWGVFP 519
[121][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 137 bits (345), Expect = 6e-31
Identities = 81/191 (42%), Positives = 111/191 (58%), Gaps = 4/191 (2%)
Frame = +2
Query: 8 RPKSYISRTIGW--DQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
RP SY++RT W D++P+GR+GDS +P+YG L R KK IE W+ P ++++
Sbjct: 339 RPYSYVARTSLWNEDEFPNGRFGDSSSPAYGDLDLCGHSLIRQSVKKSIELWSTP-QTLD 397
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
D+ + GKL+ PWS++ L E I +HL +N TINSQP VNG+ S
Sbjct: 398 DMSNLVTSYLEGKLKCLPWSDVP-LNHEVDDILKHLIDLNKHHIFTINSQPKVNGKPSTD 456
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDR-PFLTYMAVNKEGVWKSNVGQ-T 535
P VGWG GYVYQK YLEF +EKL E ++ LTY A++ + +N + +
Sbjct: 457 PVVGWGPTKGYVYQKEYLEFLLPREKLPLFQEICQEHSDHLTYFAIDSQDNLATNHPEDS 516
Query: 536 DVNAVTWGVFP 568
NAVTWGVFP
Sbjct: 517 RANAVTWGVFP 527
[122][TOP]
>UniRef100_A7TRT4 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TRT4_VANPO
Length = 645
Score = 135 bits (340), Expect = 2e-30
Identities = 75/187 (40%), Positives = 106/187 (56%), Gaps = 5/187 (2%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKD--KKLIEEWAVPLKSVEDIYER 196
+ R WD++P+GR+GDS +P+YG + Y P K KK + W P KSV D+
Sbjct: 392 LGRNATWDEFPNGRFGDSRSPAYGEIDGYG---PTLKVGIKKAYDLWGTP-KSVIDLKSV 447
Query: 197 FRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGW 376
F + G + PW +L GL PET +I E L ++N +G+LT+ SQPA N S GW
Sbjct: 448 FIKYLEGSISALPWCDL-GLSPETALIQEELIQLNQRGYLTLASQPATNASPSTDKIFGW 506
Query: 377 GGPGGYVYQKAYLEFFCSKEKLDALVEKTKD---RPFLTYMAVNKEGVWKSNVGQTDVNA 547
G GYVYQKA++E F K++ +A+V+ D R +Y + G ++SN+ N
Sbjct: 507 GPKNGYVYQKAFVEMFILKKQWEAIVKPKLDHYPRGKFSYYVGDSSGSFESNLETNSSNV 566
Query: 548 VTWGVFP 568
VTWGVFP
Sbjct: 567 VTWGVFP 573
[123][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 134 bits (336), Expect = 6e-30
Identities = 80/196 (40%), Positives = 104/196 (53%), Gaps = 9/196 (4%)
Frame = +2
Query: 8 RPKSYISRTIGW--DQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
RP SY++RT W D++P+GR+GDS +P++G L R ++ +E W+ P K
Sbjct: 335 RPYSYVARTSQWTADEFPNGRFGDSSSPAFGDLDLLGSTSIRQSPQRALELWSTPTK-FS 393
Query: 182 DIYERFRLFCLGKLRTNPWS------ELDGLQPETKIINEHLEKINTKGFLTINSQPAVN 343
DI + GKL+ PW E+D P+ +N+H+ LT+NSQP VN
Sbjct: 394 DIAALVIDYLHGKLKCLPWCDVALNHEVDTTMPQLLDLNKHM-------ILTLNSQPRVN 446
Query: 344 GEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSN 523
G S VGWG GYVYQK YLEF K KL L + D P LTY AV+ SN
Sbjct: 447 GASSADKIVGWGPNNGYVYQKQYLEFLLPKSKLSQLRDFVNDMPSLTYFAVDSADELHSN 506
Query: 524 -VGQTDVNAVTWGVFP 568
T NAVTWG+FP
Sbjct: 507 HPDDTAANAVTWGIFP 522
[124][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 133 bits (334), Expect = 1e-29
Identities = 80/191 (41%), Positives = 107/191 (56%), Gaps = 4/191 (2%)
Frame = +2
Query: 8 RPKSYISRTIGW--DQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
RP SY++RT W D++P+GR+GDS +P+YG L R ++ +E W+ P +++
Sbjct: 338 RPYSYVARTSQWSADEFPNGRFGDSSSPAYGDLDLCGHTVLRQTYQRSLELWSTP-RTLL 396
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
D+ + G L+ PWS++ L E + + L ++N LTINSQP VNG S
Sbjct: 397 DLAALVISYLKGDLKCLPWSDVP-LHQEADALLDSLIRLNEHLVLTINSQPKVNGAPSAD 455
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDAL-VEKTKDRPFLTYMAVNKEGVWKSN-VGQT 535
P VGWG GYVYQK YLEF K L A T D P LTY AV+ + SN T
Sbjct: 456 PIVGWGPANGYVYQKQYLEFLLPKHHLPAFHAALTADFPTLTYFAVDADDNLASNHPDDT 515
Query: 536 DVNAVTWGVFP 568
NAVTWG+FP
Sbjct: 516 QANAVTWGIFP 526
[125][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 132 bits (331), Expect = 2e-29
Identities = 65/144 (45%), Positives = 90/144 (62%), Gaps = 9/144 (6%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKK--LIEEWAVPLKS 175
A+RPKSYI RT WD +P+GRWG+S +P++G L DY ++K K L++ W L S
Sbjct: 372 ASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALLQMWGEELLS 431
Query: 176 VEDIYERFRLF-------CLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
E ++E F + C K+ PW++ + L ET ++ + LEK+N +G LTINSQP
Sbjct: 432 EESVFEVFTFYITAQSNRCGQKVLCLPWND-EPLAQETNLLKDELEKVNRRGVLTINSQP 490
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQK 406
+NG+ S P VGWG GGYVYQK
Sbjct: 491 NINGKPSTDPIVGWGPAGGYVYQK 514
[126][TOP]
>UniRef100_C9S7I3 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S7I3_9PEZI
Length = 312
Score = 132 bits (331), Expect = 2e-29
Identities = 77/187 (41%), Positives = 100/187 (53%)
Frame = +2
Query: 8 RPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDI 187
R KSYI RT WD++P+GRWGDS +P++G L Y ++ I++W P ++V+DI
Sbjct: 51 RNKSYILRTQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGTNEQN-IKKWGEP-QTVQDI 108
Query: 188 YERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPT 367
L TN E I E L +N +G +TINSQPAVNG KS
Sbjct: 109 AT------LESPLTN----------EADPIREDLIALNKRGIITINSQPAVNGVKSSHAV 152
Query: 368 VGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVNA 547
GWG GYVYQK+YLE + ++ + + P +TY AV K G K N NA
Sbjct: 153 HGWGPKNGYVYQKSYLEMLVHPDLYPEIISRIEKHPDMTYYAVTKSGNLKYNAPSDGPNA 212
Query: 548 VTWGVFP 568
VTWGVFP
Sbjct: 213 VTWGVFP 219
[127][TOP]
>UniRef100_B6JY06 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6JY06_SCHJY
Length = 626
Score = 131 bits (329), Expect = 4e-29
Identities = 70/182 (38%), Positives = 102/182 (56%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 202
+ R WD Y +GR+GD +P+YG + Y A ++ L + W P+ +DI F+
Sbjct: 376 LGREATWDDYTNGRFGDPRSPAYGNIDGYGPSLHFAPEESL-KLWGYPVDE-DDITNIFK 433
Query: 203 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 382
LG+ PW + ++ ETK I + L K+ K + T+ SQPAVN S GWG
Sbjct: 434 RHVLGETTAIPWID-QPVEAETKTIGDKLAKLIEKKWWTVGSQPAVNAAPSSHAIFGWGP 492
Query: 383 PGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGV 562
GG+V+QKA++E F S +AL ++ D P +TY+A N +G +K+N NAVTWGV
Sbjct: 493 RGGWVFQKAFVEMFMSTMDFEALAQRLHDNPQITYLAGNNKGEFKTNASLDSANAVTWGV 552
Query: 563 FP 568
FP
Sbjct: 553 FP 554
[128][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 130 bits (326), Expect = 9e-29
Identities = 75/196 (38%), Positives = 112/196 (57%), Gaps = 8/196 (4%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALT-DYQFMRPRAKDKKLIEE---WAVPLK 172
NR KS+I RT WD++P+GR G+ + +YG +++ ++K + W +
Sbjct: 305 NRQKSFIQRTSSWDEFPNGRLGNQASAAYGDFELNFRSYSKETQEKVAADRRRMWGDHVP 364
Query: 173 SVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEK 352
+ + + F F G+++ PW + ET I + L ++N LTINSQP VNG
Sbjct: 365 NGDHVRRVFTDFIKGEVKRLPWCTEPPTE-ETLFIQKQLIRLNQCNMLTINSQPRVNGAL 423
Query: 353 SDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF--LTYMAVNKEG-VWKSN 523
S P VGWG GG+VYQKAY+EFFC + +L+ L+ + + ++YMAV +G +SN
Sbjct: 424 STDPYVGWGPAGGFVYQKAYVEFFCPEGQLEQLIRGIEAEKYDSISYMAVTADGSKVRSN 483
Query: 524 V-GQTDVNAVTWGVFP 568
+ Q VNAVTWGVFP
Sbjct: 484 IPPQGQVNAVTWGVFP 499
[129][TOP]
>UniRef100_Q752W6 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q752W6_ASHGO
Length = 635
Score = 129 bits (324), Expect = 2e-28
Identities = 70/184 (38%), Positives = 102/184 (55%), Gaps = 2/184 (1%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 202
+ R WD++P+GR+GDS +P+YG + Y + +KK + W P ++ DI F
Sbjct: 383 LGRDATWDEFPNGRFGDSRSPAYGEIDGYG-PSLKVSNKKAYQIWGYP-STLNDIKSLFI 440
Query: 203 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 382
+ G + PW +L GL PET +I E L +N +GFLT+ SQPA N S GWG
Sbjct: 441 GYLEGSIEALPWCDL-GLSPETALIQEELIGLNQRGFLTLASQPATNSTPSADKIFGWGP 499
Query: 383 PGGYVYQKAYLEFFCSKEKLDALVEKTKDRP--FLTYMAVNKEGVWKSNVGQTDVNAVTW 556
PGG VYQKA++E F K + +A ++ + P +Y + G + SN+ + VTW
Sbjct: 500 PGGVVYQKAFVELFVEKARWEAELKPRLEGPDSKFSYYFGDSAGSFASNMAPESSSVVTW 559
Query: 557 GVFP 568
GVFP
Sbjct: 560 GVFP 563
[130][TOP]
>UniRef100_Q5A5S8 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5A5S8_CANAL
Length = 640
Score = 129 bits (324), Expect = 2e-28
Identities = 71/191 (37%), Positives = 106/191 (55%), Gaps = 5/191 (2%)
Frame = +2
Query: 14 KSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYE 193
K + + WD +P+GR+GDS +P+YG + Y + +W P +S+ D+ +
Sbjct: 380 KGALGKDAIWDDFPNGRFGDSNSPAYGEIDGYGPTLKIHTPAEASTKWGTP-ESIADLTQ 438
Query: 194 RFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVG 373
F + GK+ PW++ L PET +I E L ++N KG+ ++ SQPAVNG KS G
Sbjct: 439 VFINYLSGKVDVVPWAD-SSLSPETALIQEELFQLNEKGWFSVASQPAVNGCKSTDNIFG 497
Query: 374 WGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVG-----QTD 538
WG G +YQK+++E F KE L+ K + +TY NK+G KSN+ +
Sbjct: 498 WGPRNGIIYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVGNKDGEIKSNLPIGPNVKLS 557
Query: 539 VNAVTWGVFPA 571
NAVTWGVFP+
Sbjct: 558 KNAVTWGVFPS 568
[131][TOP]
>UniRef100_C4YKV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=C4YKV3_CANAL
Length = 640
Score = 129 bits (324), Expect = 2e-28
Identities = 71/191 (37%), Positives = 106/191 (55%), Gaps = 5/191 (2%)
Frame = +2
Query: 14 KSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYE 193
K + + WD +P+GR+GDS +P+YG + Y + +W P +S+ D+ +
Sbjct: 380 KGALGKDAIWDDFPNGRFGDSNSPAYGEIDGYGPTLKIHTPAEASTKWGTP-ESIADLTQ 438
Query: 194 RFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVG 373
F + GK+ PW++ L PET +I E L ++N KG+ ++ SQPAVNG KS G
Sbjct: 439 VFINYLSGKVDVVPWAD-SSLSPETALIQEELFQLNEKGWFSVASQPAVNGCKSTDNIFG 497
Query: 374 WGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVG-----QTD 538
WG G +YQK+++E F KE L+ K + +TY NK+G KSN+ +
Sbjct: 498 WGPRNGIIYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVGNKDGEIKSNLPIGPNVKLS 557
Query: 539 VNAVTWGVFPA 571
NAVTWGVFP+
Sbjct: 558 KNAVTWGVFPS 568
[132][TOP]
>UniRef100_Q6FNS2 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FNS2_CANGA
Length = 645
Score = 129 bits (323), Expect = 2e-28
Identities = 67/191 (35%), Positives = 108/191 (56%), Gaps = 3/191 (1%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
+R + R WD++P+GR+GDS +P+YG + Y + +K+ E W P S+ D
Sbjct: 386 SRGSGVLGRDATWDEFPNGRFGDSRSPAYGEIDGYG-PSLKVSNKRAYELWGSPT-SIRD 443
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ F + G +++ PW +L GL PET +I E L ++N +G+LT+ SQP N S
Sbjct: 444 LKAVFVKYLEGSIQSLPWCDL-GLSPETALIQEELIQLNYRGYLTLASQPCTNASSSTDK 502
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD---RPFLTYMAVNKEGVWKSNVGQT 535
GWG G+VYQKA++E F +++ +++ D R +Y A + +G +++N+
Sbjct: 503 IFGWGPSKGHVYQKAFIEMFVHRQQWKTILKPKLDYYGRRKFSYYAGDSKGSFETNLDPH 562
Query: 536 DVNAVTWGVFP 568
N VTWGVFP
Sbjct: 563 SSNVVTWGVFP 573
[133][TOP]
>UniRef100_B2WHR5 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WHR5_PYRTR
Length = 653
Score = 128 bits (322), Expect = 3e-28
Identities = 69/181 (38%), Positives = 99/181 (54%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 202
+ R WD +P+GRWGD+ +P++G + Y + ++ W P++ +DI FR
Sbjct: 404 LGREATWDDFPNGRWGDARSPAFGEIDGYG-PTLHVSTPQALKLWGYPVEK-KDISTLFR 461
Query: 203 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 382
G L PWSE GL PET I+ L +N KG+ T+ SQPAVNG KS P GWG
Sbjct: 462 RHIEGDLEAIPWSE-QGLSPETSTISAQLLALNAKGWWTVASQPAVNGVKSTDPIFGWGP 520
Query: 383 PGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGV 562
GYV+QK ++EFF + A K + +T+ A N G ++++ + VN VTWG
Sbjct: 521 KNGYVFQKPFVEFFIPAAEFQAFKPKLQAHDQVTWFAGNAAGAFEAS-QEDGVNPVTWGT 579
Query: 563 F 565
F
Sbjct: 580 F 580
[134][TOP]
>UniRef100_B2B6X0 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B6X0_PODAN
Length = 691
Score = 128 bits (322), Expect = 3e-28
Identities = 72/195 (36%), Positives = 106/195 (54%), Gaps = 13/195 (6%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 202
+ R WD +P+GRWGD+ +P+YG + Y + + + W P ++ EDI F
Sbjct: 428 LGREATWDDFPNGRWGDARSPAYGQIDGYG-VSLHVTVAQALRIWGTP-RTTEDINNVFI 485
Query: 203 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 382
G+L T PWSE +G PET I + L K+N+KG+ ++ SQPAVNG +S PT GWG
Sbjct: 486 RHLKGELTTIPWSE-EGFSPETDKIRDQLIKLNSKGWWSLASQPAVNGLRSSDPTFGWGP 544
Query: 383 PGGYVYQKAYLEFFCSKEKLDALVEKTKD---RPFLTYMAVNKEGVWKSN---------- 523
G+V+QKA++EFF L +K + + + + A+N G + S+
Sbjct: 545 ANGFVFQKAFVEFFIPSADWKVLEQKLRHPDLKDDVCFYAINAAGDFVSSDTAGSLEAEG 604
Query: 524 VGQTDVNAVTWGVFP 568
+ NAVTWGVFP
Sbjct: 605 EKEASTNAVTWGVFP 619
[135][TOP]
>UniRef100_Q6CR34 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CR34_KLULA
Length = 649
Score = 128 bits (321), Expect = 4e-28
Identities = 71/187 (37%), Positives = 111/187 (59%), Gaps = 5/187 (2%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAK--DKKLIEEWAVPLKSVEDIYER 196
+ R + WD++P+GR+GDS +P+YG + Y P K + E W P+ S+EDI
Sbjct: 397 LGRNVTWDEFPNGRFGDSRSPAYGEIDGYG---PSLKVCNSTAYELWDHPV-SLEDIKNI 452
Query: 197 FRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGW 376
F + G ++ PWS+L GL ET I E L ++N +G+L++ SQPA NG +S GW
Sbjct: 453 FIRYLEGSMKALPWSDL-GLSAETAFIQEELIELNQRGYLSLASQPATNGSQSTDNIFGW 511
Query: 377 GGPGGYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSNVGQTDVNA 547
G G +YQKA++E F KE+ + +++ ++K+ F Y+ + G +++N+ NA
Sbjct: 512 GPANGLIYQKAFVEIFVRKEEWNQVLKPKIESKNGEFSYYLG-DYTGYFETNLQPKSSNA 570
Query: 548 VTWGVFP 568
VTWGVFP
Sbjct: 571 VTWGVFP 577
[136][TOP]
>UniRef100_Q0UB79 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UB79_PHANO
Length = 543
Score = 128 bits (321), Expect = 4e-28
Identities = 69/181 (38%), Positives = 99/181 (54%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 202
+ R WD +P+GRWGD+ +P++G + Y + ++ W P+ +DI FR
Sbjct: 294 LGREATWDDFPNGRWGDARSPAFGEIDGYG-PTLHVSTTQALKLWGHPVDK-QDISALFR 351
Query: 203 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 382
G+L PWSE GL PET I + L +N KG+ T+ SQPAVNG +S P GWG
Sbjct: 352 KHLEGELEALPWSE-QGLSPETSTIAKQLLALNAKGWWTVASQPAVNGVRSTDPVFGWGP 410
Query: 383 PGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGV 562
GYV+QK ++EFF + AL + +TY A N G ++++ + VN VTWG
Sbjct: 411 KNGYVFQKPFVEFFLPAAEFHALRTRLDAHDQVTYFAGNANGDFEAS-SEESVNPVTWGT 469
Query: 563 F 565
F
Sbjct: 470 F 470
[137][TOP]
>UniRef100_Q6CEM7 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CEM7_YARLI
Length = 625
Score = 127 bits (319), Expect = 6e-28
Identities = 71/185 (38%), Positives = 102/185 (55%), Gaps = 3/185 (1%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 202
+ R WD +P+GR+GDS +P++G + Y + +E W P+ D+ + F
Sbjct: 373 VGREAVWDDFPNGRFGDSSSPAFGEIDGYG-PSIHVPPARALELWGYPVDDA-DLSKLFA 430
Query: 203 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 382
+GKL PWS+ L PET +I E L ++N KG T+ SQPA N KSD GWG
Sbjct: 431 DTIVGKLPFMPWSD-QTLSPETMLIQEQLMELNQKGIWTVASQPACNALKSDDNIFGWGP 489
Query: 383 PGGYVYQKAYLEFFCSKE---KLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVT 553
GGYV+QK++ EFF S E KL L++ +D ++Y + + +NV + N VT
Sbjct: 490 KGGYVFQKSFAEFFISPEQWKKLKPLLDAQED--LVSYYVAKSDKLVDTNVSERASNGVT 547
Query: 554 WGVFP 568
WGVFP
Sbjct: 548 WGVFP 552
[138][TOP]
>UniRef100_C5DPF1 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5DPF1_ZYGRC
Length = 650
Score = 127 bits (318), Expect = 8e-28
Identities = 70/186 (37%), Positives = 106/186 (56%), Gaps = 5/186 (2%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 202
+ R WD++P+GR+GD+ +P++G + Y + +KK E W P K+++D+ F
Sbjct: 396 LGRDATWDEFPNGRFGDTRSPAFGEIDGYG-PTLKVSNKKAYELWGQP-KTIQDLQIIFI 453
Query: 203 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 382
+ G + PW +L GL PET +I E L ++N +GFLT+ SQPA NG S + GWG
Sbjct: 454 KYLEGSIDALPWCDL-GLSPETALIQEELIQLNERGFLTLASQPATNGSPSTNKIFGWGP 512
Query: 383 PGGYVYQKAYLEFFCSKE-----KLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVNA 547
G VYQKA++E F K + +E+ R LTY A + +G +++N+ N
Sbjct: 513 AYGVVYQKAFIEMFVPKNIWENGNMKKAIEQ-YGRAKLTYYANDSQGNFETNLESNSSNV 571
Query: 548 VTWGVF 565
VTWGVF
Sbjct: 572 VTWGVF 577
[139][TOP]
>UniRef100_Q6BM19 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=Q6BM19_DEBHA
Length = 642
Score = 125 bits (315), Expect = 2e-27
Identities = 71/195 (36%), Positives = 106/195 (54%), Gaps = 9/195 (4%)
Frame = +2
Query: 14 KSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYE 193
K + + WD +P+GR+GDS +P+YG + Y ++ I +W P +SV +I +
Sbjct: 377 KGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPTLKIYSPEEAIHKWGAP-ESVNEIIK 435
Query: 194 RFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVG 373
F + GK+ + PW + L PET +I E L ++N KG+ ++ SQPAVNG S G
Sbjct: 436 VFVSYLSGKIDSLPWVDA-ALSPETALIQEELFEVNNKGWFSLASQPAVNGCLSSDKIFG 494
Query: 374 WGGPGGYVYQKAYLEFFCSKE----KLDALVEKTKDRPFLTYMAVNKEGVWKSNVG---- 529
WG G +YQKA++E F K+ KL ++K D +TY + EG SN+
Sbjct: 495 WGPGNGIIYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTITYYCGDAEGRLTSNLNIDQE 554
Query: 530 -QTDVNAVTWGVFPA 571
NA+TWGVFP+
Sbjct: 555 HYNSKNAITWGVFPS 569
[140][TOP]
>UniRef100_UPI00003BE162 hypothetical protein DEHA0F09867g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE162
Length = 642
Score = 125 bits (314), Expect = 2e-27
Identities = 71/194 (36%), Positives = 105/194 (54%), Gaps = 9/194 (4%)
Frame = +2
Query: 14 KSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYE 193
K + + WD +P+GR+GDS +P+YG + Y ++ I +W P +SV +I +
Sbjct: 377 KGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPTLKIYSPEEAIHKWGAP-ESVNEIIK 435
Query: 194 RFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVG 373
F + GK+ + PW + L PET +I E L ++N KG+ ++ SQPAVNG S G
Sbjct: 436 VFVSYLSGKIDSLPWVDA-ALSPETALIQEELFEVNNKGWFSLASQPAVNGCLSSDKIFG 494
Query: 374 WGGPGGYVYQKAYLEFFCSKE----KLDALVEKTKDRPFLTYMAVNKEGVWKSNVG---- 529
WG G +YQKA++E F K+ KL ++K D +TY + EG SN+
Sbjct: 495 WGPGNGIIYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTITYYCGDAEGRLTSNLNIDQE 554
Query: 530 -QTDVNAVTWGVFP 568
NA+TWGVFP
Sbjct: 555 HYNSKNAITWGVFP 568
[141][TOP]
>UniRef100_B9WCV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WCV3_CANDC
Length = 640
Score = 125 bits (314), Expect = 2e-27
Identities = 68/191 (35%), Positives = 106/191 (55%), Gaps = 5/191 (2%)
Frame = +2
Query: 14 KSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYE 193
K + + WD +P+GR+GDS +P+YG + Y ++ +W P +S+ D+
Sbjct: 380 KGALGKDAIWDDFPNGRFGDSNSPAYGEIDGYGPTLKIHTPEEASTKWGTP-ESLADLTR 438
Query: 194 RFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVG 373
F + GK+ PW++ L PET +I E L ++N KG+ ++ SQPA+NG KS G
Sbjct: 439 VFINYLSGKVDVIPWAD-SSLSPETALIQEELFQLNEKGWFSVASQPAINGCKSTDNIFG 497
Query: 374 WGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNV-----GQTD 538
WG G +YQK+++E F KE L+ K + +TY +K+G +SN+ +
Sbjct: 498 WGPRNGTIYQKSFIELFMPKEDWTKLLLKIELDKTVTYYVGDKDGEIRSNLPIGPNAKLS 557
Query: 539 VNAVTWGVFPA 571
NAVTWGVFP+
Sbjct: 558 KNAVTWGVFPS 568
[142][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TTE9_VANPO
Length = 612
Score = 125 bits (314), Expect = 2e-27
Identities = 77/196 (39%), Positives = 109/196 (55%), Gaps = 8/196 (4%)
Frame = +2
Query: 5 NRPKSYISRTIGW--DQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSV 178
+RP SY++RT W D++P+GR+GDS +P++G L R ++ +E WA+P S+
Sbjct: 330 SRPYSYVARTSQWAADEFPNGRFGDSSSPAFGDLDLCGSTLLRQSAQRSLELWAMP-SSI 388
Query: 179 EDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFL-TINSQPAVNGEKS 355
D+ + G+LR PWS+ + E +I L +N + + TINSQP VNG +S
Sbjct: 389 RDVAMLVVAYLQGELRCLPWSDTP-VSSEVDVIRRQLIALNEQQLIVTINSQPQVNGLRS 447
Query: 356 DSPTVGWGGPGGYVYQKAYLEFFCSK---EKLDALVEKTKD-RPFLTYMAVNKEGVWKSN 523
+ GWG GYVYQK YLEF + E+L + KT + LTY+A + G W SN
Sbjct: 448 NVKGFGWGPSDGYVYQKQYLEFLLPRARFERLQQELSKTNETTSSLTYLAADSHGGWWSN 507
Query: 524 VGQ-TDVNAVTWGVFP 568
AVTWGVFP
Sbjct: 508 QPDGAKATAVTWGVFP 523
[143][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 124 bits (312), Expect = 4e-27
Identities = 74/193 (38%), Positives = 106/193 (54%), Gaps = 5/193 (2%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALT-DYQFMRPRAKDKKLIEEWAVPLKSVE 181
NR KS+I RT WD++P+GR G+ + +YG +++ +DK +
Sbjct: 305 NRQKSFIQRTSSWDEFPNGRLGNQASAAYGDFELNFRSYSKETQDKVFTD---------- 354
Query: 182 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDS 361
F G+++ PW + ET I + L ++N LTINSQP VNG S
Sbjct: 355 --------FIKGEVKRLPWCTEPPTE-ETLFIQKQLIRLNQCNMLTINSQPRVNGALSTD 405
Query: 362 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF--LTYMAVNKEG-VWKSNV-G 529
P VGWG GG+VYQKAY+EFFC + +L+ L+ + + ++YMAV +G +SN+
Sbjct: 406 PYVGWGPAGGFVYQKAYVEFFCPEGQLEQLIRGIEAEKYDSISYMAVTADGSKVRSNIPP 465
Query: 530 QTDVNAVTWGVFP 568
Q VNAVTWGVFP
Sbjct: 466 QGQVNAVTWGVFP 478
[144][TOP]
>UniRef100_A3LW82 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LW82_PICST
Length = 635
Score = 124 bits (311), Expect = 5e-27
Identities = 71/195 (36%), Positives = 108/195 (55%), Gaps = 9/195 (4%)
Frame = +2
Query: 14 KSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYE 193
K + + WD +P+GR+GDS +P+YG + Y A ++ I +W P +SV DI +
Sbjct: 372 KGALGKEAIWDDFPNGRFGDSNSPAYGEIDGYGPSLKVASPEEAIAKWGSP-ESVGDIAK 430
Query: 194 RFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVG 373
F + GK+ PW++ L ET +I E L +N +G+ ++ SQPAVNG KS G
Sbjct: 431 VFMGYLSGKIDILPWTD-SSLSAETTLIQEELFDLNDRGWFSLASQPAVNGCKSTDRIFG 489
Query: 374 WGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF----LTYMAVNKEGVWKSNV----- 526
WG G VYQKA++E F KE+ ++ ++ + F +TY + EG +SN+
Sbjct: 490 WGPKNGIVYQKAFVEIFVPKEQWESELKSSLKPHFEEKTITYYVGDAEGNIESNLFVGPD 549
Query: 527 GQTDVNAVTWGVFPA 571
NA+TWGVFP+
Sbjct: 550 AHNSKNAITWGVFPS 564
[145][TOP]
>UniRef100_C7GU28 Met12p n=2 Tax=Saccharomyces cerevisiae RepID=C7GU28_YEAS2
Length = 657
Score = 122 bits (307), Expect = 1e-26
Identities = 67/185 (36%), Positives = 105/185 (56%), Gaps = 3/185 (1%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 202
+ R WD++P+GR+GDS +P+YG + Y +K K L E W +P K++ D+ + F
Sbjct: 402 LGRDATWDEFPNGRFGDSRSPAYGEIDGYGPSIKVSKSKAL-ELWGIP-KTIGDLKDIFI 459
Query: 203 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 382
+ G PWS+L GL ET +I E L ++N +G+LT+ SQPA N S GWG
Sbjct: 460 KYLEGSTDAIPWSDL-GLSAETALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGP 518
Query: 383 PGGYVYQKAYLEFFCSKEKLDALVEKTKD---RPFLTYMAVNKEGVWKSNVGQTDVNAVT 553
G +YQKA++E F +++ + ++ D R +Y A + G +++N+ + VT
Sbjct: 519 AKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVT 578
Query: 554 WGVFP 568
WGVFP
Sbjct: 579 WGVFP 583
[146][TOP]
>UniRef100_B5VTD9 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VTD9_YEAS6
Length = 657
Score = 122 bits (307), Expect = 1e-26
Identities = 67/185 (36%), Positives = 105/185 (56%), Gaps = 3/185 (1%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 202
+ R WD++P+GR+GDS +P+YG + Y +K K L E W +P K++ D+ + F
Sbjct: 402 LGRDATWDEFPNGRFGDSRSPAYGEIDGYGPSIKVSKSKAL-ELWGIP-KTIGDLKDIFI 459
Query: 203 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 382
+ G PWS+L GL ET +I E L ++N +G+LT+ SQPA N S GWG
Sbjct: 460 KYLEGSTDAIPWSDL-GLSAETALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGP 518
Query: 383 PGGYVYQKAYLEFFCSKEKLDALVEKTKD---RPFLTYMAVNKEGVWKSNVGQTDVNAVT 553
G +YQKA++E F +++ + ++ D R +Y A + G +++N+ + VT
Sbjct: 519 AKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVT 578
Query: 554 WGVFP 568
WGVFP
Sbjct: 579 WGVFP 583
[147][TOP]
>UniRef100_B3LL40 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LL40_YEAS1
Length = 657
Score = 122 bits (307), Expect = 1e-26
Identities = 67/185 (36%), Positives = 105/185 (56%), Gaps = 3/185 (1%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 202
+ R WD++P+GR+GDS +P+YG + Y +K K L E W +P K++ D+ + F
Sbjct: 402 LGRDATWDEFPNGRFGDSRSPAYGEIDGYGPSIKVSKSKAL-ELWGIP-KTIGDLKDIFI 459
Query: 203 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 382
+ G PWS+L GL ET +I E L ++N +G+LT+ SQPA N S GWG
Sbjct: 460 KYLEGSTDAIPWSDL-GLSAETALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGP 518
Query: 383 PGGYVYQKAYLEFFCSKEKLDALVEKTKD---RPFLTYMAVNKEGVWKSNVGQTDVNAVT 553
G +YQKA++E F +++ + ++ D R +Y A + G +++N+ + VT
Sbjct: 519 AKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVT 578
Query: 554 WGVFP 568
WGVFP
Sbjct: 579 WGVFP 583
[148][TOP]
>UniRef100_A5DE00 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DE00_PICGU
Length = 642
Score = 122 bits (307), Expect = 1e-26
Identities = 69/195 (35%), Positives = 106/195 (54%), Gaps = 9/195 (4%)
Frame = +2
Query: 14 KSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYE 193
K + + WD +P+GR+GDS +P+YG + Y ++ I +W P +S +DI +
Sbjct: 379 KGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPSLKIHSPQEAIAKWGTP-ESTKDISK 437
Query: 194 RFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVG 373
F + GK+ PW + L ET +I E L ++N KG+ ++ SQP+VNG +S G
Sbjct: 438 VFLNYLSGKINILPWVDAP-LSAETALIQEELFELNDKGWFSLASQPSVNGARSSDKIFG 496
Query: 374 WGGPGGYVYQKAYLEFFCSKE----KLDALVEKTKDRPFLTYMAVNKEGVWKSNV----- 526
WG G+V+QK+++E F KE KL ++ D +TY A + G +SN+
Sbjct: 497 WGPSNGFVFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDITYYAGDSSGKIQSNLPVGPD 556
Query: 527 GQTDVNAVTWGVFPA 571
NAVTWGVFP+
Sbjct: 557 SHNSKNAVTWGVFPS 571
[149][TOP]
>UniRef100_P46151 Methylenetetrahydrofolate reductase 1 n=1 Tax=Saccharomyces
cerevisiae RepID=MTHR1_YEAST
Length = 657
Score = 122 bits (307), Expect = 1e-26
Identities = 67/185 (36%), Positives = 105/185 (56%), Gaps = 3/185 (1%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 202
+ R WD++P+GR+GDS +P+YG + Y +K K L E W +P K++ D+ + F
Sbjct: 402 LGRDATWDEFPNGRFGDSRSPAYGEIDGYGPSIKVSKSKAL-ELWGIP-KTIGDLKDIFI 459
Query: 203 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 382
+ G PWS+L GL ET +I E L ++N +G+LT+ SQPA N S GWG
Sbjct: 460 KYLEGSTDAIPWSDL-GLSAETALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGP 518
Query: 383 PGGYVYQKAYLEFFCSKEKLDALVEKTKD---RPFLTYMAVNKEGVWKSNVGQTDVNAVT 553
G +YQKA++E F +++ + ++ D R +Y A + G +++N+ + VT
Sbjct: 519 AKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVT 578
Query: 554 WGVFP 568
WGVFP
Sbjct: 579 WGVFP 583
[150][TOP]
>UniRef100_UPI000151A866 hypothetical protein PGUG_01501 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151A866
Length = 642
Score = 122 bits (306), Expect = 2e-26
Identities = 69/194 (35%), Positives = 105/194 (54%), Gaps = 9/194 (4%)
Frame = +2
Query: 14 KSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYE 193
K + + WD +P+GR+GDS +P+YG + Y ++ I +W P +S +DI +
Sbjct: 379 KGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPSLKIHSPQEAIAKWGTP-ESTKDISK 437
Query: 194 RFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVG 373
F + GK+ PW + L ET +I E L ++N KG+ ++ SQP+VNG +S G
Sbjct: 438 VFLNYLSGKINILPWVDAP-LSAETALIQEELFELNDKGWFSLASQPSVNGARSSDKIFG 496
Query: 374 WGGPGGYVYQKAYLEFFCSKE----KLDALVEKTKDRPFLTYMAVNKEGVWKSNV----- 526
WG G+V+QK+++E F KE KL ++ D +TY A + G +SN+
Sbjct: 497 WGPSNGFVFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDITYYAGDSSGKIQSNLPVGPD 556
Query: 527 GQTDVNAVTWGVFP 568
NAVTWGVFP
Sbjct: 557 SHNSKNAVTWGVFP 570
[151][TOP]
>UniRef100_C5DIA7 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5DIA7_LACTC
Length = 660
Score = 121 bits (304), Expect = 3e-26
Identities = 68/179 (37%), Positives = 101/179 (56%), Gaps = 3/179 (1%)
Frame = +2
Query: 41 WDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGK 220
WD++ +GR+GDS +P++G + Y + KK E W P S +DI F + G
Sbjct: 414 WDEFTNGRFGDSRSPAFGEIDGYG-PSLKVSSKKAYEIWGQP-SSTDDIKTLFIRYLEGS 471
Query: 221 LRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVY 400
L PWS+L GL ET +I E L ++N +G+L++ SQPA N S GWG PGGYVY
Sbjct: 472 LEALPWSDL-GLSAETALIQEELIQLNERGYLSLASQPATNSTPSTDKIFGWGPPGGYVY 530
Query: 401 QKAYLEFFCSKEKLDALVEKTKDRPF---LTYMAVNKEGVWKSNVGQTDVNAVTWGVFP 568
QK+++E F K++ + L K K P ++Y + + +N+ + + VTWGVFP
Sbjct: 531 QKSFVEMFVHKQQWE-LEIKPKLEPLGSKVSYYVGDSAETFYTNLDSSCSSVVTWGVFP 588
[152][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri NRRL
181 RepID=A1CZX0_NEOFI
Length = 716
Score = 120 bits (301), Expect = 7e-26
Identities = 76/206 (36%), Positives = 108/206 (52%), Gaps = 25/206 (12%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEE--WAVPLKSVEDIYER 196
+ R WD +P+GRWGD+ +P++G + Y P + W P+ S EDI
Sbjct: 428 LGREATWDDFPNGRWGDARSPAFGEIDGYG---PSLHVSGAVARRIWGYPV-SREDISAL 483
Query: 197 FRLFCLGKLRTNPWSE------LDGLQPETKIINEHLEK-INTKGFLTINSQPAVNGEKS 355
FR G L PWSE GL ET++I L K I++KG+ T+ SQPAVNG +S
Sbjct: 484 FRRHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLIDSKGWWTLASQPAVNGVRS 543
Query: 356 DSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSN 523
D PT GWG PG G+V+QK ++EFFC + +++ L + A N +G ++S+
Sbjct: 544 DDPTFGWGPPGEGFVFQKPFVEFFCPSKDFQTVLKPLFAKHGHEKLAWFATNVKGEFESS 603
Query: 524 ------------VGQTDVNAVTWGVF 565
+ +VNAVTWGVF
Sbjct: 604 LPADPAHADTIEMNPNNVNAVTWGVF 629
[153][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 120 bits (300), Expect = 1e-25
Identities = 68/182 (37%), Positives = 109/182 (59%), Gaps = 6/182 (3%)
Frame = +2
Query: 41 WDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLG- 217
WD++P+GR+ D +P+YG + + + + ++EW VP+ S D+ F +
Sbjct: 380 WDEFPNGRFTDVRSPAYGEIDGWG-SGLKITAAQALKEWGVPV-STSDLSALFTAYLHSD 437
Query: 218 -KLRTNPWSELDGLQPETKIINEHLEKINTKGFL--TINSQPAVNGEKSDSPTVGWGGPG 388
K T P+ +L L PE+ +I HL +N+ T+ SQPAV+ KS+ VGWG G
Sbjct: 438 PKHLTTPFCDLP-LSPESHMILPHLLALNSANVQHWTVGSQPAVDAAKSEDEVVGWGPRG 496
Query: 389 GYVYQKAYLEFFCSKEKLDALVEKT--KDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGV 562
GYV+QKA++EFF ++++++ L EK + + +T A N++G +K+N + VNAVTWGV
Sbjct: 497 GYVFQKAFVEFFVTEDEVNRLKEKVEREGKGLITMYAANRKGDFKTNTDKDSVNAVTWGV 556
Query: 563 FP 568
FP
Sbjct: 557 FP 558
[154][TOP]
>UniRef100_A7E9M9 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7E9M9_SCLS1
Length = 663
Score = 119 bits (299), Expect = 1e-25
Identities = 73/188 (38%), Positives = 102/188 (54%), Gaps = 6/188 (3%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 202
+ R WD +P+GRWGD+ +P+YG + Y + + I+ W P S DI + F
Sbjct: 409 LGREATWDDFPNGRWGDARSPAYGEIDGYG-VSLHMSINQAIKLWGHP-SSRADITDIFI 466
Query: 203 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 382
G+L PWSE +GL ET I + L +N KG+ T+ SQPAVNG KS GWG
Sbjct: 467 RHLEGQLTAIPWSE-EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGVKSTDSIFGWGP 525
Query: 383 PGGYVYQKAYLEFFCSKEKLDALVEKTKD---RPFLTYMAVNKEGVWKSN---VGQTDVN 544
G+V+QKA++E F +AL K R +++ A N +G + S+ +G T N
Sbjct: 526 KNGFVFQKAFVELFLPTSDWEALQAKLTSPALRDTVSFYASNAKGDFISSDEAIGST--N 583
Query: 545 AVTWGVFP 568
AVTWG FP
Sbjct: 584 AVTWGAFP 591
[155][TOP]
>UniRef100_A4RH85 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RH85_MAGGR
Length = 662
Score = 119 bits (298), Expect = 2e-25
Identities = 71/205 (34%), Positives = 106/205 (51%), Gaps = 23/205 (11%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 202
+ R WD YP+GRWGD+ +P+YG + Y + + ++ W P +VED+ F
Sbjct: 389 LGREATWDDYPNGRWGDARSPAYGEIDGYG-VSLHMSGTQAVQLWGRPA-TVEDVSNIFM 446
Query: 203 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 382
G L PWSE + ET+ I + L +N++G+ T+ SQPAVNG +S+ T GWG
Sbjct: 447 RHLRGALPAIPWSE-EEFNAETETIRDTLLALNSRGWWTVASQPAVNGLRSNDRTFGWGP 505
Query: 383 PGGYVYQKAYLEFFCSKEKLDALVEK-TKDRPFLTYMAVNKEGVWKSNVGQTD------- 538
G+V+QKA++E F + AL EK ++ + + A N +G ++S+ G D
Sbjct: 506 QNGFVFQKAFVEMFLPSKDWKALREKLLSEKDVVCFYASNAKGDFESSDGGGDAPDGAPT 565
Query: 539 ---------------VNAVTWGVFP 568
NAVTWGVFP
Sbjct: 566 GNGFADEQPLPSGSSTNAVTWGVFP 590
[156][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 119 bits (297), Expect = 2e-25
Identities = 71/203 (34%), Positives = 111/203 (54%), Gaps = 14/203 (6%)
Frame = +2
Query: 2 ANRPKSY-ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSV 178
A SY + T WD++P+GR+GDS +P++G + Y + + + + W P+ S+
Sbjct: 413 ARTSSSYQVPETSTWDEFPNGRYGDSRSPAFGEMDGYG-VSLKVPPQDALRIWGHPV-SL 470
Query: 179 EDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINT----------KGFLTINS 328
DI F + K+ PW + L ET I +HL +N KG+ ++ S
Sbjct: 471 TDISRIFGFYLEEKISCIPWCDAP-LMNETLQIRDHLLTLNRLAENASQSAGKGWWSVGS 529
Query: 329 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCS---KEKLDALVEKTKDRPFLTYMAVN 499
QPAV+G S P VG+G PGG+V+QK+++E F S K++L A ++ +TY A N
Sbjct: 530 QPAVDGAPSTDPIVGFGPPGGFVFQKSFVELFVSSSDKDRLVARIDALGASAPITYFAGN 589
Query: 500 KEGVWKSNVGQTDVNAVTWGVFP 568
+G ++SN+G + N VTW VFP
Sbjct: 590 AKGDFQSNLGDEEANTVTWAVFP 612
[157][TOP]
>UniRef100_C9S8T9 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S8T9_9PEZI
Length = 670
Score = 119 bits (297), Expect = 2e-25
Identities = 72/194 (37%), Positives = 100/194 (51%), Gaps = 12/194 (6%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 202
+ R WD +P+GRWGD+ +P+YG + Y + + + W P SV DI F
Sbjct: 408 LGREATWDDFPNGRWGDARSPAYGEIDGYG-VSLHMSVTQAVRLWGHPKSSV-DISTLFI 465
Query: 203 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 382
G+L PWSE +GL PET II E L ++NT+G+ T+ SQPAVNG S T GWG
Sbjct: 466 KHIRGELSAIPWSE-EGLSPETNIIQEQLIELNTRGWWTVASQPAVNGVPSRDATFGWGP 524
Query: 383 PGGYVYQKAYLEFFCSKEKLDALVEK---TKDRPFLTYMAVNKEGVWKSN---------V 526
G+V+QKA++E F L E+ + + + A N G + ++
Sbjct: 525 SHGFVFQKAFVELFLPAADWKVLSERLTGPEVEGTVCFYACNGNGDFATSDDSGGLVRTA 584
Query: 527 GQTDVNAVTWGVFP 568
NAVTWGVFP
Sbjct: 585 VPASTNAVTWGVFP 598
[158][TOP]
>UniRef100_A2QUJ5 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QUJ5_ASPNC
Length = 699
Score = 119 bits (297), Expect = 2e-25
Identities = 78/206 (37%), Positives = 111/206 (53%), Gaps = 25/206 (12%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDY-QFMRPRAKDKKLIEEWAVPLKSVEDIYERF 199
+ R WD +P+GRWGD+ +P++G + Y + A + I W P+ EDI F
Sbjct: 410 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVSAATARRI--WGYPVTR-EDISTLF 466
Query: 200 RLFCLGKLRTNPWSE------LDGLQPETKIIN-EHLEKINTKGFLTINSQPAVNGEKSD 358
R G+L PWSE +GL ET II E L I+ KG+ T+ SQPA+NG +SD
Sbjct: 467 RRHVSGELHMVPWSEGGAEEDSNGLNAETAIIQPELLTLIDKKGWWTLASQPAINGVRSD 526
Query: 359 SPTVGWGGPG-GYVYQKAYLEFFC-SKEKLDAL--VEKTKDRPFLTYMAVNKEGVWKS-- 520
P GWG PG G+V+QK ++EFFC +K+ L L + + L + A N +G ++S
Sbjct: 527 DPVFGWGPPGEGFVFQKPFVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNVKGDFESSL 586
Query: 521 -----------NVGQTDVNAVTWGVF 565
++ +VNAVTWGVF
Sbjct: 587 PGPNTDDPDPIDINPANVNAVTWGVF 612
[159][TOP]
>UniRef100_UPI000023F2EE hypothetical protein FG07127.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023F2EE
Length = 672
Score = 118 bits (296), Expect = 3e-25
Identities = 70/195 (35%), Positives = 109/195 (55%), Gaps = 13/195 (6%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 202
+ R WD +P+GR+GD+ +P+YG + Y + + ++ W P K+ +DI + F
Sbjct: 409 LGREATWDDFPNGRFGDARSPAYGEIDGYG-VSLHMSVTQAVKLWDYP-KTRQDINDLFV 466
Query: 203 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 382
G+L PWSE + L+ E+ I HL ++N KG+ T+ SQPAVNG +S T GWG
Sbjct: 467 KHIQGELSAIPWSE-EELRAESSTIKPHLLQLNGKGWWTVASQPAVNGLRSSDATFGWGP 525
Query: 383 PGGYVYQKAYLEFFCSK---EKLDALVEKTKDRPFLTYMAVNKEGVW-KSNVG------- 529
P G+V+QK+++EFF E L A + ++ + ++ + A N G + S++G
Sbjct: 526 PNGFVFQKSFVEFFIPANEWEILKAKLVSSELQDYVCFYASNARGDYVSSDIGGHVDGST 585
Query: 530 --QTDVNAVTWGVFP 568
NAVTWGVFP
Sbjct: 586 EASPSTNAVTWGVFP 600
[160][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 118 bits (296), Expect = 3e-25
Identities = 76/206 (36%), Positives = 107/206 (51%), Gaps = 25/206 (12%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEE--WAVPLKSVEDIYER 196
+ R WD +P+GRWGD+ +P++G + Y P + W P+ S EDI
Sbjct: 401 LGREATWDDFPNGRWGDARSPAFGEIDGYG---PSLHVSGAVARRIWGYPV-SREDISAL 456
Query: 197 FRLFCLGKLRTNPWSE------LDGLQPETKIINEHLEK-INTKGFLTINSQPAVNGEKS 355
FR G L PWSE GL ET++I L K I+ KG+ T+ SQPAVNG +S
Sbjct: 457 FRRHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRS 516
Query: 356 DSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSN 523
D PT GWG PG G+V+QK ++EFFC + +++ L + A N +G ++S+
Sbjct: 517 DDPTFGWGPPGEGFVFQKPFVEFFCPSKDFRTVLKPLFAKHGHEKLAWFATNVKGEFESS 576
Query: 524 ------------VGQTDVNAVTWGVF 565
+ +VNAVTWGVF
Sbjct: 577 LPADPAHADTIEMNPNNVNAVTWGVF 602
[161][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR2_SCHPO
Length = 641
Score = 118 bits (296), Expect = 3e-25
Identities = 65/184 (35%), Positives = 100/184 (54%), Gaps = 2/184 (1%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDY--QFMRPRAKDKKLIEEWAVPLKSVEDIYER 196
+ R WD + +GR+GD +P+YG + Y P ++ KL W P+ DI
Sbjct: 389 LGRQANWDDFTNGRFGDPRSPAYGEIDGYGPTLHFPPSEALKL---WGYPVDE-SDITSL 444
Query: 197 FRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGW 376
F+ + + PW + + ++ ETK I ++L K+N + T+ SQPAVNG S P GW
Sbjct: 445 FQKHIMSDISAIPWID-EPVEVETKTIAKYLLKLNGNSWWTVGSQPAVNGAPSADPVFGW 503
Query: 377 GGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTW 556
G GG V+QKA++E F + + L + K D P +TY A N + + +N + +AVTW
Sbjct: 504 GPKGGRVFQKAFVECFVNGKDLKDFITKWHDNPQVTYYAGNNKSEFLTNAPKDGASAVTW 563
Query: 557 GVFP 568
GV+P
Sbjct: 564 GVYP 567
[162][TOP]
>UniRef100_Q7S2B6 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S2B6_NEUCR
Length = 681
Score = 118 bits (295), Expect = 4e-25
Identities = 71/207 (34%), Positives = 105/207 (50%), Gaps = 25/207 (12%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 202
+ R WD +P+GRWGD+ +P+YG + Y + + ++ W P K+ EDI + F
Sbjct: 406 LGREATWDDFPNGRWGDARSPAYGQIDGYG-VSLHVTVPQALQLWGSP-KTTEDINKIFI 463
Query: 203 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 382
G+L PWSE +G ET+ I ++L ++N++G+ ++ SQPAVNG +SD T GWG
Sbjct: 464 RHLKGELSAIPWSE-EGFNDETEAIRDNLIELNSRGWWSLASQPAVNGLRSDDGTFGWGP 522
Query: 383 PGGYVYQKAYLEFFCSKEKLDALVEKTKDRP-----------------------FLTYMA 493
G+V+QKA++EFF L K K F MA
Sbjct: 523 ENGFVFQKAFVEFFIPSADWRVLEAKLKQPDMKDTVCFFATNAAGDFVSTDTINFRARMA 582
Query: 494 VNKEGVWKSN--VGQTDVNAVTWGVFP 568
EG +++ + NAVTWGVFP
Sbjct: 583 AEAEGTAEADHRPHEPSTNAVTWGVFP 609
[163][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 118 bits (295), Expect = 4e-25
Identities = 76/206 (36%), Positives = 107/206 (51%), Gaps = 25/206 (12%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEE--WAVPLKSVEDIYER 196
+ R WD +P+GRWGD+ +P++G + Y P + W P+ S EDI
Sbjct: 401 LGREATWDDFPNGRWGDARSPAFGEIDGYG---PSLHVSGAVARRIWGYPV-SREDISAL 456
Query: 197 FRLFCLGKLRTNPWSE------LDGLQPETKIINEHLEK-INTKGFLTINSQPAVNGEKS 355
FR G L PWSE GL ET++I L K I+ KG+ T+ SQPAVNG +S
Sbjct: 457 FRHHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRS 516
Query: 356 DSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSN 523
D PT GWG PG G+V+QK ++EFFC + +++ L + A N +G ++S+
Sbjct: 517 DDPTFGWGPPGEGFVFQKPFVEFFCPSKDFRTVLKPLFAKHGHEKLAWFATNVKGEFESS 576
Query: 524 ------------VGQTDVNAVTWGVF 565
+ +VNAVTWGVF
Sbjct: 577 LPADPAHADTIEMNPNNVNAVTWGVF 602
[164][TOP]
>UniRef100_A1C4Z1 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C4Z1_ASPCL
Length = 690
Score = 118 bits (295), Expect = 4e-25
Identities = 74/206 (35%), Positives = 109/206 (52%), Gaps = 25/206 (12%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEE--WAVPLKSVEDIYER 196
+ R WD +P+GRWGD+ +P++G + Y P + W P+ S +DI
Sbjct: 402 LGREATWDDFPNGRWGDARSPAFGEIDGYG---PSLHVSPTVARRVWGYPV-SRDDISTL 457
Query: 197 FRLFCLGKLRTNPWSE------LDGLQPETKIINEHLEK-INTKGFLTINSQPAVNGEKS 355
FR G+L PWSE GL ET++I L K I+ KG+ T+ SQPAVNG +S
Sbjct: 458 FRRHVSGELYIVPWSEGGAEENTSGLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRS 517
Query: 356 DSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSN 523
D+ T GWG PG G+V+QK ++EFFC + + +++ L + A N +G ++S+
Sbjct: 518 DNSTFGWGPPGEGFVFQKPFVEFFCPSKDFETVLKPLFANHGHEKLAWFATNAKGEFQSS 577
Query: 524 V------------GQTDVNAVTWGVF 565
+ +VNAVTWGVF
Sbjct: 578 LPAETADSDALEPNPDNVNAVTWGVF 603
[165][TOP]
>UniRef100_C7YTQ6 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YTQ6_NECH7
Length = 674
Score = 117 bits (294), Expect = 5e-25
Identities = 71/195 (36%), Positives = 103/195 (52%), Gaps = 13/195 (6%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 202
+ R WD +P+GR+GD+ +P+YG + Y + + ++ W P K+ +DI + F
Sbjct: 411 LGREATWDDFPNGRFGDARSPAYGEIDGYG-VSLHMSITQAVKLWGHP-KTRQDINDLFV 468
Query: 203 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 382
G+L PWSE + L E+ I HL ++N KG+ T+ SQPAVNG +S T GWG
Sbjct: 469 KHIQGQLSAIPWSE-EELLAESSTIQPHLLRLNQKGWWTVASQPAVNGLRSSDGTFGWGP 527
Query: 383 PGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF---LTYMAVNKEG--VWKSNVGQTD--- 538
P G+V+QK+++EFF + L EK + + A N +G V G D
Sbjct: 528 PNGFVFQKSFVEFFIPSSEWSVLKEKLNSSELCDSVCFYAGNAKGDFVSSDKGGHVDGSS 587
Query: 539 -----VNAVTWGVFP 568
NAVTWGVFP
Sbjct: 588 GAGPSTNAVTWGVFP 602
[166][TOP]
>UniRef100_C8V780 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5AU15] n=2 Tax=Emericella
nidulans RepID=C8V780_EMENI
Length = 684
Score = 117 bits (293), Expect = 6e-25
Identities = 78/208 (37%), Positives = 108/208 (51%), Gaps = 27/208 (12%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQ---FMRPRAKDKKLIEEWAVPLKSVEDIYE 193
+ R WD +P+GRWGD+ +P++G + Y + P + W P+ S +DI +
Sbjct: 397 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVAPSVAHRI----WGYPV-STDDISK 451
Query: 194 RFRLFCLGKLRTNPWSE------LDGLQPETKIIN-EHLEKINTKGFLTINSQPAVNGEK 352
FR G L PWSE GL ET+ I E L I+ KG+ T+ SQPAVNG +
Sbjct: 452 LFRRHVSGDLHMVPWSEGGAEENTSGLNAETETIRPELLALIDKKGWWTLASQPAVNGVR 511
Query: 353 SDSPTVGWGGPG-GYVYQKAYLEFFCS----KEKLDALVEKTKDRPFLTYMAVNKEGVWK 517
SD P GWG PG G+V+QK ++EFFC K L L++K L + A N G ++
Sbjct: 512 SDDPIFGWGPPGEGFVFQKPFVEFFCPASDFKTTLKPLLQK-HGHEKLAWFATNAAGDFE 570
Query: 518 SN------------VGQTDVNAVTWGVF 565
S+ + +VNAVTWGVF
Sbjct: 571 SSLPAETSDTEPVEMNPNNVNAVTWGVF 598
[167][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NEV2_COPC7
Length = 617
Score = 117 bits (293), Expect = 6e-25
Identities = 63/179 (35%), Positives = 101/179 (56%), Gaps = 3/179 (1%)
Frame = +2
Query: 41 WDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDK-KLIEEWAVPLKSVEDIYERFRLFCLG 217
WD +P+GR+GD +P++G + + + +++W P K+ +D+ F
Sbjct: 363 WDDFPNGRFGDFKSPAFGNQDPWGGPGGLGISRAEALQQWGYP-KTFDDLTRIFLAHLHS 421
Query: 218 KLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYV 397
++ P+S + L PE+ I HLE++ +G+ T+ SQPAV+G S T GWG GYV
Sbjct: 422 EIPITPFSPTE-LCPESITILPHLERLTKRGWWTVGSQPAVDGISSSDETFGWGPRAGYV 480
Query: 398 YQKAYLEFFCSKEKLDALVEKTKDR--PFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFP 568
+QK ++EFFC ++A+ ++ K R ++ Y N G +SNV + NAVTWGVFP
Sbjct: 481 FQKGFVEFFCDFHDVEAIEQRIKQRGAGWVHYFMANNNGECRSNVPEDGRNAVTWGVFP 539
[168][TOP]
>UniRef100_A7QB32 Chromosome chr5 scaffold_72, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7QB32_VITVI
Length = 170
Score = 117 bits (292), Expect = 8e-25
Identities = 67/143 (46%), Positives = 84/143 (58%), Gaps = 1/143 (0%)
Frame = +2
Query: 74 SGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDG 253
S NPSYGAL DYQFMRP A DKKL EEW VPLKSVEDI +RF FC GKL+ PW E +G
Sbjct: 3 SCNPSYGALIDYQFMRPHACDKKLQEEWVVPLKSVEDIQKRFMKFCRGKLKNGPWKEFEG 62
Query: 254 LQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGY-VYQKAYLEFFCS 430
LQP+TKII+E + IN KG P + WGG G ++ K ++ + S
Sbjct: 63 LQPDTKIIDEPIGNINLKGKWGKIGLP-----------IWWGGVGQVGMFTKRLMQSYPS 111
Query: 431 KEKLDALVEKTKDRPFLTYMAVN 499
+ L+E+ + FL + N
Sbjct: 112 R----ILLEEVQSSYFLVSLVDN 130
[169][TOP]
>UniRef100_C5M548 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M548_CANTT
Length = 633
Score = 115 bits (289), Expect = 2e-24
Identities = 65/191 (34%), Positives = 101/191 (52%), Gaps = 5/191 (2%)
Frame = +2
Query: 14 KSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYE 193
K + + WD +P+GR+GDS +P+YG + Y + +W P ++ +D+ +
Sbjct: 373 KGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPTLKIHSPAEAEIKWGSP-ETTKDLAQ 431
Query: 194 RFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVG 373
F + GK+ PW++ L PET +I E L ++N KG+ ++ SQPA N KS G
Sbjct: 432 IFIDYLSGKIDVIPWAD-QALSPETALIQEELFQLNEKGWFSVASQPAANACKSTDNIFG 490
Query: 374 WGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVG-----QTD 538
WG G VYQKA++E F K+ + L + +TY A +K ++ V +
Sbjct: 491 WGPRNGVVYQKAFVELFMPKDDWNKLKPLVEASDSITYYAADKTNKIEAKVPAGHDIKLT 550
Query: 539 VNAVTWGVFPA 571
NAVTWGVFP+
Sbjct: 551 KNAVTWGVFPS 561
[170][TOP]
>UniRef100_C4R2L4 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2L4_PICPG
Length = 596
Score = 115 bits (289), Expect = 2e-24
Identities = 63/178 (35%), Positives = 100/178 (56%), Gaps = 2/178 (1%)
Frame = +2
Query: 41 WDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGK 220
WD +P+GR+GDS +P+YG + Y + + + W P+ ++DI + F + +
Sbjct: 349 WDDFPNGRYGDSRSPAYGEIDGYG-PSLKVSSSRAYKLWGYPV-DLDDITKIFIAYLSNR 406
Query: 221 LRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVY 400
+ PWSEL GL PET +I E L ++N K TI+SQP+ NG KS GWG GYVY
Sbjct: 407 ITALPWSEL-GLNPETGLIQEELIQLNEKHMFTISSQPSANGVKSTDKLFGWGPSEGYVY 465
Query: 401 QKAYLEFFCSKEKL-DALVEKTKDRPFLTYMAVNKEGVWKSNVG-QTDVNAVTWGVFP 568
QKA++E F +K++ + ++ + +T+ + + +N+ N+VTWG FP
Sbjct: 466 QKAFVEVFINKKQWNEEILPNLQGHKSVTWYLGDCNNAFDTNIKIPLSSNSVTWGCFP 523
[171][TOP]
>UniRef100_C1H0K0 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1H0K0_PARBA
Length = 713
Score = 115 bits (289), Expect = 2e-24
Identities = 75/212 (35%), Positives = 109/212 (51%), Gaps = 31/212 (14%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDY-QFMRPRAKDKKLIEEWAVPLKSVEDIYERF 199
+ R WD +P+GRWGD+ +P++G + Y + A + + W P S EDI + F
Sbjct: 409 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVNANVARQL--WGYPT-SKEDINKLF 465
Query: 200 RLFCLGKLRTNPWSE------LDGLQPETKIINEHL-EKINTKGFLTINSQPAVNGEKSD 358
G+L PWSE GL ET I E L + I+ +G+ T+ SQPAVNG +SD
Sbjct: 466 HCHVSGELHIVPWSEGGSAEDSGGLNAETATIREELLQLIDGRGWWTLASQPAVNGVRSD 525
Query: 359 SPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSN- 523
P GWG G G+V+QKA++EFFCS + + +++ K + L++ A N G ++S+
Sbjct: 526 HPIFGWGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQSSS 585
Query: 524 ------------------VGQTDVNAVTWGVF 565
VNAVTWGVF
Sbjct: 586 SFTGITGLDDAVPDYNGAASSNGVNAVTWGVF 617
[172][TOP]
>UniRef100_C1GJU2 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1GJU2_PARBD
Length = 712
Score = 115 bits (288), Expect = 2e-24
Identities = 75/212 (35%), Positives = 109/212 (51%), Gaps = 31/212 (14%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDY-QFMRPRAKDKKLIEEWAVPLKSVEDIYERF 199
+ R WD +P+GRWGD+ +P++G + Y + A + + W P S EDI + F
Sbjct: 409 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVNANVARQL--WGYPT-SREDINKLF 465
Query: 200 RLFCLGKLRTNPWSE------LDGLQPETKIINEHL-EKINTKGFLTINSQPAVNGEKSD 358
G+L PWSE GL ET I E L + I+ +G+ T+ SQPAVNG +SD
Sbjct: 466 HCHVSGELHIVPWSEGGSAEDSGGLNAETATIREELLQLIDGRGWWTLASQPAVNGVRSD 525
Query: 359 SPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSN- 523
P GWG G G+V+QKA++EFFCS + + +++ K + L++ A N G ++S+
Sbjct: 526 HPIFGWGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQSSS 585
Query: 524 ------------------VGQTDVNAVTWGVF 565
VNAVTWGVF
Sbjct: 586 SFTGTTGLDDAVPDYNGAASSNGVNAVTWGVF 617
[173][TOP]
>UniRef100_C0S8C4 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0S8C4_PARBP
Length = 712
Score = 115 bits (288), Expect = 2e-24
Identities = 75/212 (35%), Positives = 109/212 (51%), Gaps = 31/212 (14%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDY-QFMRPRAKDKKLIEEWAVPLKSVEDIYERF 199
+ R WD +P+GRWGD+ +P++G + Y + A + + W P S EDI + F
Sbjct: 409 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVNANVARQL--WGYPT-SREDINKLF 465
Query: 200 RLFCLGKLRTNPWSE------LDGLQPETKIINEHL-EKINTKGFLTINSQPAVNGEKSD 358
G+L PWSE GL ET I E L + I+ +G+ T+ SQPAVNG +SD
Sbjct: 466 HCHVSGELHIVPWSEGGSAEDSGGLNAETATIREELLQLIDGRGWWTLASQPAVNGVRSD 525
Query: 359 SPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSN- 523
P GWG G G+V+QKA++EFFCS + + +++ K + L++ A N G ++S+
Sbjct: 526 HPIFGWGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQSSS 585
Query: 524 ------------------VGQTDVNAVTWGVF 565
VNAVTWGVF
Sbjct: 586 SFTGTTGLDDAVPDYSGAASSNGVNAVTWGVF 617
[174][TOP]
>UniRef100_A6RQJ7 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6RQJ7_BOTFB
Length = 663
Score = 114 bits (285), Expect = 5e-24
Identities = 72/188 (38%), Positives = 99/188 (52%), Gaps = 6/188 (3%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 202
+ R WD +P+GRWGD+ +P+YG + Y + + I+ W P S DI + F
Sbjct: 409 LGREATWDDFPNGRWGDARSPAYGEIDGYG-VSLHMSINQAIKLWGHP-SSRADITDIFI 466
Query: 203 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGG 382
G+L PWSE +GL ET I + L +N KG+ T+ SQPAVNG KS GWG
Sbjct: 467 RHLEGQLTAIPWSE-EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGLKSSDSIFGWGP 525
Query: 383 PGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF---LTYMAVNKEGVWKSN---VGQTDVN 544
G+V+QKA++E F L K +++ A N +G + S+ VG T N
Sbjct: 526 KNGFVFQKAFVELFIPVADWKTLHAKLTSPDLCDTVSFYASNAKGDFISSDEAVGST--N 583
Query: 545 AVTWGVFP 568
AVTWG FP
Sbjct: 584 AVTWGAFP 591
[175][TOP]
>UniRef100_A5DZ35 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DZ35_LODEL
Length = 622
Score = 114 bits (285), Expect = 5e-24
Identities = 65/193 (33%), Positives = 104/193 (53%), Gaps = 5/193 (2%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
+R K + + WD +P+GR+GDS +P+YG + Y + I +W P ++++
Sbjct: 362 SRGKGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPSLKIHNASEAIAKWGSPT-NIKE 420
Query: 185 IYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSP 364
+ + F + GK+ PW++ L PET +I E L ++N KG+ ++ SQPAVNG +S+
Sbjct: 421 LGQVFVDYLSGKIDVVPWADTS-LSPETALIQEELFELNQKGWFSVASQPAVNGCRSNDN 479
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEG-----VWKSNVG 529
GWG G VYQK+++E F + L + D TY +K G ++ +
Sbjct: 480 VFGWGPGNGVVYQKSFVELFIPAKDWKELKPRLDDA--TTYYVGDKSGRIELSLFTNEST 537
Query: 530 QTDVNAVTWGVFP 568
+ NAVTWGVFP
Sbjct: 538 RHLKNAVTWGVFP 550
[176][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 114 bits (284), Expect = 7e-24
Identities = 65/180 (36%), Positives = 103/180 (57%), Gaps = 4/180 (2%)
Frame = +2
Query: 41 WDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGK 220
WD +P+GR+GD +P++G + D ++ +W P KS++D+ + F K
Sbjct: 351 WDDFPNGRFGDFKSPAFGNQDLWGGSGISGSD--VLAQWNNP-KSLDDLTQIFLGHLHAK 407
Query: 221 LRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVY 400
+ T P+S L E+ +I HLE++ + + T+ SQPAV+G S VGWG GGYV+
Sbjct: 408 ILTTPFSPTP-LSSESLMILPHLERLTRRSWWTVGSQPAVDGVSSGDKVVGWGPRGGYVF 466
Query: 401 QKAYLEFFCSKEKLDALVEKTK--DRPFLTYMAVN--KEGVWKSNVGQTDVNAVTWGVFP 568
QK ++EFFC ++ +D + + + ++ Y A N +G +SNV + NAVTWGVFP
Sbjct: 467 QKGFVEFFCEEKDMDVIERRVERNGHGWVHYFAGNYKADGECRSNVPEGGRNAVTWGVFP 526
[177][TOP]
>UniRef100_Q0CE17 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CE17_ASPTN
Length = 696
Score = 113 bits (283), Expect = 9e-24
Identities = 76/207 (36%), Positives = 109/207 (52%), Gaps = 26/207 (12%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQ---FMRPRAKDKKLIEEWAVPLKSVEDIYE 193
+ R WD +P+GRWGD+ +P++G + Y + P + W P+ +DI
Sbjct: 409 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTPSVAHRI----WGYPVTR-DDINT 463
Query: 194 RFRLFCLGKLRTNPWSE------LDGLQPETKIIN-EHLEKINTKGFLTINSQPAVNGEK 352
FR G+L PWSE GL PET+ I E L+ I+ KG+ T+ SQPAVNG +
Sbjct: 464 LFRRHVSGELHMVPWSEGGAEEGSGGLNPETETIRPELLQLIDGKGWWTLASQPAVNGVR 523
Query: 353 SDSPTVGWGGP-GGYVYQKAYLEFFC-SKEKLDAL--VEKTKDRPFLTYMAVNKEGVWKS 520
SD P GWG P G+V+QK ++EFFC +K+ AL + + L + A N G ++S
Sbjct: 524 SDDPIFGWGPPREGFVFQKPFVEFFCPTKDYQTALKPMLQKHGHEKLAWFATNANGDFES 583
Query: 521 N------------VGQTDVNAVTWGVF 565
+ + +VNAVTWGVF
Sbjct: 584 SLPAQTSDADPIEMNPNNVNAVTWGVF 610
[178][TOP]
>UniRef100_Q2UA39 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus oryzae
RepID=Q2UA39_ASPOR
Length = 690
Score = 112 bits (281), Expect = 2e-23
Identities = 72/206 (34%), Positives = 108/206 (52%), Gaps = 25/206 (12%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDY--QFMRPRAKDKKLIEEWAVPLKSVEDIYER 196
+ R WD +P+GRWGD+ +P++G + Y P A ++ W P+ S EDI
Sbjct: 401 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVPPAVAHRI---WGFPV-SHEDISAL 456
Query: 197 FRLFCLGKLRTNPWSE------LDGLQPETKIIN-EHLEKINTKGFLTINSQPAVNGEKS 355
F G+L PWSE GL ET++I E L+ I+ G+ T+ SQPAVNG +S
Sbjct: 457 FHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPELLQLIDGNGWWTLASQPAVNGVRS 516
Query: 356 DSPTVGWGGP-GGYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSN 523
D P GWG P G+V+QK ++EFFC + ++++ + L + A N +G ++S+
Sbjct: 517 DDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLLQKHGHEKLAWFAANVKGDFESS 576
Query: 524 ------------VGQTDVNAVTWGVF 565
+ +VN VTWGVF
Sbjct: 577 LPAQTSDADPIEMNPNNVNCVTWGVF 602
[179][TOP]
>UniRef100_B8NQE8 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus flavus
NRRL3357 RepID=B8NQE8_ASPFN
Length = 738
Score = 112 bits (281), Expect = 2e-23
Identities = 72/206 (34%), Positives = 108/206 (52%), Gaps = 25/206 (12%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDY--QFMRPRAKDKKLIEEWAVPLKSVEDIYER 196
+ R WD +P+GRWGD+ +P++G + Y P A ++ W P+ S EDI
Sbjct: 449 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVPPAVAHRI---WGFPV-SHEDISAL 504
Query: 197 FRLFCLGKLRTNPWSE------LDGLQPETKIIN-EHLEKINTKGFLTINSQPAVNGEKS 355
F G+L PWSE GL ET++I E L+ I+ G+ T+ SQPAVNG +S
Sbjct: 505 FHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPELLQLIDGNGWWTLASQPAVNGVRS 564
Query: 356 DSPTVGWGGP-GGYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSN 523
D P GWG P G+V+QK ++EFFC + ++++ + L + A N +G ++S+
Sbjct: 565 DDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLLQKHGHEKLAWFAANVKGDFESS 624
Query: 524 ------------VGQTDVNAVTWGVF 565
+ +VN VTWGVF
Sbjct: 625 LPAQTSDADPIEMNPNNVNCVTWGVF 650
[180][TOP]
>UniRef100_Q1DT03 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DT03_COCIM
Length = 711
Score = 112 bits (280), Expect = 2e-23
Identities = 78/218 (35%), Positives = 107/218 (49%), Gaps = 37/218 (16%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDY-QFMRPRAKDKKLIEEWAVPLKSVEDIYERF 199
+ R WD +P+GRWGD+ +P++G + Y + A + + W P EDI F
Sbjct: 407 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTANVARRL--WGYPTTR-EDINNIF 463
Query: 200 RLFCLGKLRTNPWSE------LDGLQPETKIINEHL-EKINTKGFLTINSQPAVNGEKSD 358
R G L PWSE GL PET I +L I +G+ TI SQPAV+G +SD
Sbjct: 464 RQHVSGGLHAVPWSEGGAAEETGGLSPETITIRPYLLSLIEKRGWWTIASQPAVSGVRSD 523
Query: 359 SPTVGWGGPG-GYVYQKAYLEFFCSKE----KLDALVEKTKDRPFLTYMAVNKEGVWKSN 523
P GWG PG G+V+QKA++EFFCSK+ L L+++ F + A N G ++S+
Sbjct: 524 HPIFGWGPPGEGFVFQKAFVEFFCSKDDYRSHLKPLLQRYGHDEF-AWFATNAAGDFESS 582
Query: 524 VGQT------------------------DVNAVTWGVF 565
+ VNAVTWGVF
Sbjct: 583 TSSSIPVPTGPVDAVFDDMDSFPSSNSGGVNAVTWGVF 620
[181][TOP]
>UniRef100_C4Y9Q4 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y9Q4_CLAL4
Length = 601
Score = 112 bits (280), Expect = 2e-23
Identities = 62/182 (34%), Positives = 102/182 (56%), Gaps = 5/182 (2%)
Frame = +2
Query: 41 WDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGK 220
WD +P+GR+GD+ +P+YG + Y + + + + W P +SV D+ F + K
Sbjct: 352 WDDFPNGRFGDASSPAYGEIDGYG-PSLKLEPPEAVAVWGTP-QSVADVSRVFIDYLSAK 409
Query: 221 LRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVY 400
+ + PW + L PET +I E L ++N++G T+ SQPAV+ S +GWG G ++
Sbjct: 410 ISSLPWVSTE-LSPETALIQEQLFELNSRGLFTLASQPAVDSCPSSDSILGWGPRNGRIF 468
Query: 401 QKAYLEFFCSK---EKLDALVEKTKDRPFLTYMAVNKEGVWKSNV--GQTDVNAVTWGVF 565
QK+++EFF K E+L L++K +TY N +G +N+ + A+TWGVF
Sbjct: 469 QKSFVEFFVPKTEWERLLRLMDKDISDKTITYFCGNSKGEITTNMPHKSSQRTAITWGVF 528
Query: 566 PA 571
P+
Sbjct: 529 PS 530
[182][TOP]
>UniRef100_C4JM22 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii 1704
RepID=C4JM22_UNCRE
Length = 709
Score = 112 bits (280), Expect = 2e-23
Identities = 77/218 (35%), Positives = 110/218 (50%), Gaps = 37/218 (16%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDY-QFMRPRAKDKKLIEEWAVPLKSVEDIYERF 199
+ R WD +P+GRWGD+ +P++G + Y + A + + W P S EDI + F
Sbjct: 405 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTANVARRL--WGFPT-SREDINQIF 461
Query: 200 RLFCLGKLRTNPWSE------LDGLQPETKIINEHL-EKINTKGFLTINSQPAVNGEKSD 358
R G L PWSE GL PET I +L + I+ +G+ T+ SQPAVNG +SD
Sbjct: 462 RRHVSGALHAVPWSEGGAAEESGGLNPETATIRPYLLDLIDKRGWWTLASQPAVNGVRSD 521
Query: 359 SPTVGWGGPG-GYVYQKAYLEFFCS----KEKLDALVEKTKDRPFLTYMAVNKEGVWKSN 523
T GWG PG G+V+QKA++EFFCS + L L+++ F + A N G ++++
Sbjct: 522 DTTFGWGPPGEGFVFQKAFVEFFCSSNDYRSYLKPLLQRYGHDEF-AWFATNAAGDFEAS 580
Query: 524 VGQT------------------------DVNAVTWGVF 565
+ VNAVTWGVF
Sbjct: 581 TPPSAHSPTEPVDAGFEDPSSPAASNPGGVNAVTWGVF 618
[183][TOP]
>UniRef100_C5P4Q4 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5P4Q4_COCP7
Length = 711
Score = 111 bits (278), Expect = 3e-23
Identities = 77/218 (35%), Positives = 107/218 (49%), Gaps = 37/218 (16%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDY-QFMRPRAKDKKLIEEWAVPLKSVEDIYERF 199
+ R WD +P+GRWGD+ +P++G + Y + A + + W P EDI F
Sbjct: 407 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTANVARRL--WGYPTTR-EDINNIF 463
Query: 200 RLFCLGKLRTNPWSE------LDGLQPETKIINEHL-EKINTKGFLTINSQPAVNGEKSD 358
R G L PWSE GL PET I +L I +G+ T+ SQPAV+G +SD
Sbjct: 464 RQHVSGGLHAVPWSEGGAAEETGGLSPETITIRPYLLSLIEKRGWWTLASQPAVSGVRSD 523
Query: 359 SPTVGWGGPG-GYVYQKAYLEFFCSKE----KLDALVEKTKDRPFLTYMAVNKEGVWKSN 523
P GWG PG G+V+QKA++EFFCSK+ L L+++ F + A N G ++S+
Sbjct: 524 HPIFGWGPPGEGFVFQKAFVEFFCSKDDYRSHLKPLLQRYGHDEF-AWFATNAAGDFESS 582
Query: 524 VGQT------------------------DVNAVTWGVF 565
+ VNAVTWGVF
Sbjct: 583 TSSSIPVPTGPVDAVFDDMDSFPSSNSGGVNAVTWGVF 620
[184][TOP]
>UniRef100_C5GI01 Methylenetetrahydrofolate reductase n=2 Tax=Ajellomyces dermatitidis
RepID=C5GI01_AJEDR
Length = 713
Score = 111 bits (278), Expect = 3e-23
Identities = 76/217 (35%), Positives = 107/217 (49%), Gaps = 36/217 (16%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDY--QFMRPRAKDKKLIEEWAVPLKSVEDIYER 196
+ R WD +P+GRWGD+ +P++G + Y A ++L W P EDI
Sbjct: 406 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTPAVARRL---WGYPTTK-EDINTI 461
Query: 197 FRLFCLGKLRTNPWSE-----LDGLQPETKII-NEHLEKINTKGFLTINSQPAVNGEKSD 358
F+ G L PWSE GL ET I +E L+ IN +G+ T+ SQPAVNG ++D
Sbjct: 462 FQRHVSGDLHIVPWSEGGTQDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRND 521
Query: 359 SPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSN- 523
P GWG G G+V+QKA++EFFC+ L +++ + L + A N G ++S+
Sbjct: 522 HPIFGWGPRGEGFVFQKAFVEFFCTAHDLKTILKPIFENHGHDELAWFATNAAGDFESSS 581
Query: 524 -----------------------VGQTDVNAVTWGVF 565
G T VNAVTWGVF
Sbjct: 582 PPTDDSANDYSGPVDVYLDSNATAGGTGVNAVTWGVF 618
[185][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 108 bits (271), Expect = 2e-22
Identities = 77/218 (35%), Positives = 110/218 (50%), Gaps = 37/218 (16%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDY-QFMRPRAKDKKLIEEWAVPLKSVEDIYERF 199
+ R WD +P+GRWGD+ +P++G + Y + A+ + + W P S EDI F
Sbjct: 367 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTARVARKL--WGTP-TSREDISNIF 423
Query: 200 RLFCLGKLRTNPWS-----ELDGLQPETKII-NEHLEKINTKGFLTINSQPAVNGEKSDS 361
R G+L PWS E GL PET I E L+ + +G+ T+ SQP+VNG ++D
Sbjct: 424 RRLLSGELHAVPWSEGGAGEEGGLNPETATIRTELLKLVEGRGWWTLASQPSVNGVRNDH 483
Query: 362 PTVGWGGPG-GYVYQKAYLEFFCSKE----KLDALVEKTKDRPFLTYMAVNKEGVWKSNV 526
P GWG G G+V+QKA++EFFC + KL L+ F + A+N +G ++S+
Sbjct: 484 PIFGWGPRGEGFVFQKAFVEFFCPGDDFHSKLKPLLNSYGHDEF-AWFAMNAKGDFQSST 542
Query: 527 G----------------QTD---------VNAVTWGVF 565
TD VNAVTWGVF
Sbjct: 543 SPEPPASPPTDSTEPLFDTDPLTDMDNGSVNAVTWGVF 580
[186][TOP]
>UniRef100_C0NTN2 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NTN2_AJECG
Length = 713
Score = 107 bits (266), Expect = 8e-22
Identities = 72/217 (33%), Positives = 106/217 (48%), Gaps = 36/217 (16%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDY--QFMRPRAKDKKLIEEWAVPLKSVEDIYER 196
+ R WD +P+GRWGD+ +P++G + Y A ++L W P +DI
Sbjct: 406 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVNAAVARRL---WGYPTTK-QDINNI 461
Query: 197 FRLFCLGKLRTNPWSE-----LDGLQPETKII-NEHLEKINTKGFLTINSQPAVNGEKSD 358
F+ G+L PWSE GL ET I +E L+ IN +G+ T+ SQPAVNG ++D
Sbjct: 462 FQRHVSGELHLVPWSEGGAQDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRND 521
Query: 359 SPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKS-- 520
P GWG G G+V+QKA++EFFC +++++ ++ + A N G + S
Sbjct: 522 HPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNAAGDFMSSS 581
Query: 521 ----------------------NVGQTDVNAVTWGVF 565
+ G T V AVTWGVF
Sbjct: 582 PATDATTEDSSGPVDVFLDSNVSPGNTGVTAVTWGVF 618
[187][TOP]
>UniRef100_B6HK87 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6HK87_PENCW
Length = 691
Score = 107 bits (266), Expect = 8e-22
Identities = 71/207 (34%), Positives = 108/207 (52%), Gaps = 26/207 (12%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDY-QFMRPRAKDKKLIEEWAVPLKSVEDIYERF 199
+ R WD +P+GRWGD+ +P++G + Y + A + + W P+ S +D+ F
Sbjct: 400 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTANTARRL--WGHPVDS-KDMSAIF 456
Query: 200 RLFCLGKLRTNPWSE------LDGLQPETKIIN-EHLEKINTKGFLTINSQPAVNGEKSD 358
R G+L PWSE +GL ET++I E L+ I+ +G+ T+ SQPAVNG +D
Sbjct: 457 RRHVSGELHMVPWSEGGAEEDGEGLNAETELIRPELLKLIDGRGWWTLASQPAVNGVHND 516
Query: 359 SPTVGWGGP-GGYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKSNV 526
P GWG G+V+QK ++EFFCS +++ LT+ A N +G ++S++
Sbjct: 517 HPIFGWGPQREGFVFQKPFVEFFCSSNDYTNILKPLFAKHGHDKLTWFATNVKGDFESSL 576
Query: 527 --------------GQTDVNAVTWGVF 565
VNAVTWGVF
Sbjct: 577 PAQPADMDLDDLGSNPESVNAVTWGVF 603
[188][TOP]
>UniRef100_C6HED8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6HED8_AJECH
Length = 713
Score = 106 bits (265), Expect = 1e-21
Identities = 72/217 (33%), Positives = 106/217 (48%), Gaps = 36/217 (16%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDY--QFMRPRAKDKKLIEEWAVPLKSVEDIYER 196
+ R WD +P+GRWGD+ +P++G + Y A ++L W P +DI
Sbjct: 406 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVNAAVARRL---WGYPTTK-QDINNI 461
Query: 197 FRLFCLGKLRTNPWSE-----LDGLQPETKII-NEHLEKINTKGFLTINSQPAVNGEKSD 358
F+ G+L PWSE GL ET I +E L+ IN +G+ T+ SQPAVNG ++D
Sbjct: 462 FQRHVSGELHLVPWSEGGAQDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRND 521
Query: 359 SPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKS-- 520
P GWG G G+V+QKA++EFFC +++++ ++ + A N G + S
Sbjct: 522 HPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNVAGDFMSSS 581
Query: 521 ----------------------NVGQTDVNAVTWGVF 565
+ G T V AVTWGVF
Sbjct: 582 PATDATTEDSSGPVDVFLDSNVSPGNTGVTAVTWGVF 618
[189][TOP]
>UniRef100_A6QT35 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6QT35_AJECN
Length = 712
Score = 106 bits (264), Expect = 1e-21
Identities = 72/217 (33%), Positives = 105/217 (48%), Gaps = 36/217 (16%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDY--QFMRPRAKDKKLIEEWAVPLKSVEDIYER 196
+ R WD +P+GRWGD+ +P++G + Y A ++L W P +DI
Sbjct: 405 LGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVNAAVARRL---WGYPTTK-QDINNI 460
Query: 197 FRLFCLGKLRTNPWSE-----LDGLQPETKII-NEHLEKINTKGFLTINSQPAVNGEKSD 358
F+ G+L PWSE GL ET I +E L IN +G+ T+ SQPAVNG ++D
Sbjct: 461 FQRHVSGELHLVPWSEGGAQDTGGLNAETATIRDELLHLINGRGWWTLASQPAVNGVRND 520
Query: 359 SPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVNKEGVWKS-- 520
P GWG G G+V+QKA++EFFC +++++ ++ + A N G + S
Sbjct: 521 HPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNAAGDFMSSS 580
Query: 521 ----------------------NVGQTDVNAVTWGVF 565
+ G T V AVTWGVF
Sbjct: 581 PATDAATEDFSGPVDVFLDSNVSPGNTGVTAVTWGVF 617
[190][TOP]
>UniRef100_Q3EAG8 Methylenetetrahydrofolate reductase n=1 Tax=Arabidopsis thaliana
RepID=Q3EAG8_ARATH
Length = 407
Score = 105 bits (262), Expect = 2e-21
Identities = 44/65 (67%), Positives = 54/65 (83%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
ANRPKSYISRT GW+ +PHGRWGDS + +Y L+DYQF RP+ +DKKL +EW VPLKS+E
Sbjct: 333 ANRPKSYISRTKGWNDFPHGRWGDSHSAAYSTLSDYQFARPKGRDKKLQQEWVVPLKSIE 392
Query: 182 DIYER 196
D+ ER
Sbjct: 393 DVQER 397
[191][TOP]
>UniRef100_Q9SE60-2 Isoform 2 of Methylenetetrahydrofolate reductase 1 n=1
Tax=Arabidopsis thaliana RepID=Q9SE60-2
Length = 421
Score = 103 bits (257), Expect = 9e-21
Identities = 43/64 (67%), Positives = 53/64 (82%)
Frame = +2
Query: 2 ANRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVE 181
ANRPKSYISRT GW+ +PHGRWGDS + +Y L+DYQF RP+ +DKKL +EW VPLKS+E
Sbjct: 333 ANRPKSYISRTKGWNDFPHGRWGDSHSAAYSTLSDYQFARPKGRDKKLQQEWVVPLKSIE 392
Query: 182 DIYE 193
D+ E
Sbjct: 393 DVQE 396
[192][TOP]
>UniRef100_B6QFH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QFH8_PENMQ
Length = 710
Score = 103 bits (256), Expect = 1e-20
Identities = 64/155 (41%), Positives = 84/155 (54%), Gaps = 8/155 (5%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDY-QFMRPRAKDKKLIEEWAVPLKSVEDIYERF 199
+ R WD +P+GRWGDS +P++G + Y + A K E W P+ EDI F
Sbjct: 409 LGREATWDDFPNGRWGDSRSPAFGEIDGYGPSLHVNATVAK--ELWGFPVTR-EDIGTLF 465
Query: 200 RLFCLGKLRTNPWSELDG-----LQPETKIINEHL-EKINTKGFLTINSQPAVNGEKSDS 361
R G+L PWSE L ET+II L + I K + T+ SQPAVNG +SD
Sbjct: 466 RKHVSGELYIVPWSEGGAAEDANLNAETQIIKPQLLQIIEKKNWWTLASQPAVNGVRSDH 525
Query: 362 PTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVEKT 463
P GWG PG G+V+QKA++EFFC V+ T
Sbjct: 526 PVFGWGPPGEGFVFQKAFVEFFCPNADYQNKVKPT 560
[193][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 101 bits (252), Expect = 4e-20
Identities = 59/190 (31%), Positives = 102/190 (53%), Gaps = 8/190 (4%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFR 202
IS ++ WD++P+GR+ D+ +P++G + Y + ++ + W P+ +DI F
Sbjct: 329 ISGSVTWDEFPNGRYTDARSPAFGEMDGYG-ANLKVPPEEAVRLWGTPVDE-DDISSIFS 386
Query: 203 LFCLGKLRTNPWSELDGLQPETKIINEHLEKINT------KGFLTINSQPAVNGEKSDSP 364
F G+L PW ++ + ET + L +N+ K + T+ SQPAV+G S P
Sbjct: 387 RFVDGRLACMPWCDIP-VWDETMQLLPALLHLNSPPSAGGKAWWTVGSQPAVDGCDSTDP 445
Query: 365 TVGWGGPGGYVYQKAYLEFFCSKEKLDALVE--KTKDRPFLTYMAVNKEGVWKSNVGQTD 538
T G+G GGY++QKA++E F ++ +ALV+ + P + +++N+
Sbjct: 446 TFGFGPQGGYIFQKAFVELFMNENDKNALVQMIQGSSTPVTYFAGKCDPTTFETNLTTNG 505
Query: 539 VNAVTWGVFP 568
+N VTWGVFP
Sbjct: 506 LNTVTWGVFP 515
[194][TOP]
>UniRef100_B8MDD4 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8MDD4_TALSN
Length = 713
Score = 100 bits (250), Expect = 6e-20
Identities = 62/155 (40%), Positives = 83/155 (53%), Gaps = 8/155 (5%)
Frame = +2
Query: 23 ISRTIGWDQYPHGRWGDSGNPSYGALTDY-QFMRPRAKDKKLIEEWAVPLKSVEDIYERF 199
+ R WD +P+GRWGDS +P++G + Y + A K + W P+ EDI F
Sbjct: 411 LGREATWDDFPNGRWGDSRSPAFGEIDGYGPSLHVNATVAKQL--WGFPVTR-EDIGALF 467
Query: 200 RLFCLGKLRTNPWSELDG-----LQPETKIINEHL-EKINTKGFLTINSQPAVNGEKSDS 361
R G+L PWSE L ET+ I L + I K + T+ SQPAVNG +SD
Sbjct: 468 RKHVSGELYIVPWSEGGAAEDANLNAETETIKPQLLQIIEKKNWWTLASQPAVNGVRSDH 527
Query: 362 PTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVEKT 463
P GWG PG G+V+QKA++EFFC V+ T
Sbjct: 528 PVFGWGPPGEGFVFQKAFVEFFCPSSDYQNKVKPT 562
[195][TOP]
>UniRef100_Q2HBA5 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2HBA5_CHAGB
Length = 643
Score = 92.0 bits (227), Expect = 3e-17
Identities = 58/138 (42%), Positives = 75/138 (54%)
Frame = +2
Query: 155 WAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTKGFLTINSQP 334
W P+ S DI F G+L+T PWSE + ET I + L +N+KG+ T+ SQP
Sbjct: 453 WGAPV-SPPDISAIFIRHLRGELQTIPWSE-ESFSAETDKIRDQLVALNSKGWWTLASQP 510
Query: 335 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVW 514
AVNG +S PT GWG G+V+QKA++EFF AL EK +RP EG
Sbjct: 511 AVNGLRSSDPTFGWGPQNGFVFQKAFVEFFLPLADWAAL-EKRLNRP-------EMEG-- 560
Query: 515 KSNVGQTDVNAVTWGVFP 568
+ NAV+WGVFP
Sbjct: 561 -RREREASTNAVSWGVFP 577
[196][TOP]
>UniRef100_A7S359 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
RepID=A7S359_NEMVE
Length = 102
Score = 90.9 bits (224), Expect = 6e-17
Identities = 44/89 (49%), Positives = 58/89 (65%)
Frame = +2
Query: 233 PWSELDGLQPETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAY 412
PW++ + L ET I E L N+ G L+INSQP+VN S P +GWGG GGY+YQKAY
Sbjct: 5 PWND-EELALETSFIKEKLIHFNSNGILSINSQPSVNAASSTDPLLGWGGEGGYIYQKAY 63
Query: 413 LEFFCSKEKLDALVEKTKDRPFLTYMAVN 499
LEFF S E + L+++ K+ P + Y VN
Sbjct: 64 LEFFASPEVVYILLQELKNYPQVNYHVVN 92
[197][TOP]
>UniRef100_Q497H7 Mthfr protein (Fragment) n=2 Tax=Mus musculus RepID=Q497H7_MOUSE
Length = 166
Score = 71.6 bits (174), Expect = 4e-11
Identities = 35/73 (47%), Positives = 47/73 (64%), Gaps = 1/73 (1%)
Frame = +2
Query: 353 SDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGVWKSNVG 529
S P VGWG GGYV+QKAYLEFF S+E ++AL++ K + Y V+ +G +N
Sbjct: 4 SSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAP 63
Query: 530 QTDVNAVTWGVFP 568
+ NAVTWG+FP
Sbjct: 64 ELQPNAVTWGIFP 76
[198][TOP]
>UniRef100_A6SLU6 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6SLU6_BOTFB
Length = 390
Score = 60.8 bits (146), Expect = 7e-08
Identities = 29/65 (44%), Positives = 45/65 (69%)
Frame = +2
Query: 5 NRPKSYISRTIGWDQYPHGRWGDSGNPSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVED 184
NR KSY++RT WD++P+GRWGDS +P++G L Y + + +++ I+ W P KS++D
Sbjct: 327 NRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDAYG-IGLKGSNEQNIKLWGQP-KSIKD 384
Query: 185 IYERF 199
I E F
Sbjct: 385 IAELF 389